LOCUS       DARBDN010000001       124238 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000001 DARBDN010000000
VERSION     DARBDN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 124238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 124238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..124238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.001"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(333..3044)
                     /locus_tag="SCH06_000001"
     CDS             complement(333..3044)
                     /locus_tag="SCH06_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076613.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLPQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(3054..3755)
                     /locus_tag="SCH06_000002"
     CDS             complement(3054..3755)
                     /locus_tag="SCH06_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076614.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            3941..4540
                     /locus_tag="SCH06_000003"
     CDS             3941..4540
                     /locus_tag="SCH06_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEG1076615.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTIKKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            4621..5634
                     /locus_tag="SCH06_000004"
     CDS             4621..5634
                     /locus_tag="SCH06_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEG1076616.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            5742..6659
                     /gene="rbsK"
                     /locus_tag="SCH06_000005"
     CDS             5742..6659
                     /gene="rbsK"
                     /locus_tag="SCH06_000005"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEG1076617.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            6687..7082
                     /gene="rbsD"
                     /locus_tag="SCH06_000006"
     CDS             6687..7082
                     /gene="rbsD"
                     /locus_tag="SCH06_000006"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEG1076618.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            7082..8455
                     /locus_tag="SCH06_000007"
     CDS             7082..8455
                     /locus_tag="SCH06_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1076619.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            8812..10956
                     /locus_tag="SCH06_000008"
     CDS             8812..10956
                     /locus_tag="SCH06_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEG1076620.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(11008..12048)
                     /locus_tag="SCH06_000009"
     CDS             complement(11008..12048)
                     /locus_tag="SCH06_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEG1076621.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMGNGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(12325..14127)
                     /locus_tag="SCH06_000010"
     CDS             complement(12325..14127)
                     /locus_tag="SCH06_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076622.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIILGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(14141..14893)
                     /locus_tag="SCH06_000011"
     CDS             complement(14141..14893)
                     /locus_tag="SCH06_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076623.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(14902..15264)
                     /locus_tag="SCH06_000012"
     CDS             complement(14902..15264)
                     /locus_tag="SCH06_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEG1076624.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(15440..16312)
                     /locus_tag="SCH06_000013"
     CDS             complement(15440..16312)
                     /locus_tag="SCH06_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEG1076625.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(16338..16850)
                     /locus_tag="SCH06_000014"
     CDS             complement(16338..16850)
                     /locus_tag="SCH06_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HEG1076626.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQARGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            complement(16988..17779)
                     /locus_tag="SCH06_000015"
     CDS             complement(16988..17779)
                     /locus_tag="SCH06_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEG1076627.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(17834..18442)
                     /locus_tag="SCH06_000016"
     CDS             complement(17834..18442)
                     /locus_tag="SCH06_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEG1076628.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(18435..18752)
                     /locus_tag="SCH06_000017"
     CDS             complement(18435..18752)
                     /locus_tag="SCH06_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEG1076629.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(18908..19636)
                     /locus_tag="SCH06_000018"
     CDS             complement(18908..19636)
                     /locus_tag="SCH06_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HEG1076630.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            19795..20676
                     /locus_tag="SCH06_000019"
     CDS             19795..20676
                     /locus_tag="SCH06_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1076631.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARNFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(20913..21956)
                     /locus_tag="SCH06_000020"
     CDS             complement(20913..21956)
                     /locus_tag="SCH06_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1076632.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIG
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(21959..22627)
                     /locus_tag="SCH06_000021"
     CDS             complement(21959..22627)
                     /locus_tag="SCH06_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1076633.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            22769..25105
                     /locus_tag="SCH06_000022"
     CDS             22769..25105
                     /locus_tag="SCH06_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1076634.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(25220..25531)
                     /locus_tag="SCH06_000023"
     CDS             complement(25220..25531)
                     /locus_tag="SCH06_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076635.1"
                     /translation="MKKMKESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            25712..27187
                     /locus_tag="SCH06_000024"
     CDS             25712..27187
                     /locus_tag="SCH06_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HEG1076636.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            27234..27818
                     /locus_tag="SCH06_000025"
     CDS             27234..27818
                     /locus_tag="SCH06_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HEG1076637.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            27820..28239
                     /locus_tag="SCH06_000026"
     CDS             27820..28239
                     /locus_tag="SCH06_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HEG1076638.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKTL"
     gene            complement(28520..28804)
                     /locus_tag="SCH06_000027"
     CDS             complement(28520..28804)
                     /locus_tag="SCH06_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HEG1076639.1"
                     /translation="MREIYSFESKIYASEVDKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNMPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(29156..29866)
                     /locus_tag="SCH06_000028"
     CDS             complement(29156..29866)
                     /locus_tag="SCH06_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HEG1076640.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(29863..31335)
                     /locus_tag="SCH06_000029"
     CDS             complement(29863..31335)
                     /locus_tag="SCH06_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEG1076641.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            31473..31946
                     /locus_tag="SCH06_000030"
     CDS             31473..31946
                     /locus_tag="SCH06_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEG1076642.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(32099..32650)
                     /locus_tag="SCH06_000031"
     CDS             complement(32099..32650)
                     /locus_tag="SCH06_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEG1076643.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            32755..33285
                     /locus_tag="SCH06_000032"
     CDS             32755..33285
                     /locus_tag="SCH06_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HEG1076644.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(33768..34211)
                     /locus_tag="SCH06_000033"
     CDS             complement(33768..34211)
                     /locus_tag="SCH06_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1076645.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(34227..35387)
                     /locus_tag="SCH06_000034"
     CDS             complement(34227..35387)
                     /locus_tag="SCH06_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEG1076646.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKKQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            35894..37594
                     /locus_tag="SCH06_000035"
     CDS             35894..37594
                     /locus_tag="SCH06_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076647.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQKKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(37696..38529)
                     /locus_tag="SCH06_000036"
     CDS             complement(37696..38529)
                     /locus_tag="SCH06_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEG1076648.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCQVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(38833..40998)
                     /locus_tag="SCH06_000037"
     CDS             complement(38833..40998)
                     /locus_tag="SCH06_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1076649.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            41258..43552
                     /locus_tag="SCH06_000038"
     CDS             41258..43552
                     /locus_tag="SCH06_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEG1076650.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGFPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            43545..44210
                     /gene="pgmB"
                     /locus_tag="SCH06_000039"
     CDS             43545..44210
                     /gene="pgmB"
                     /locus_tag="SCH06_000039"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEG1076651.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKCH
                     DHG"
     gene            44203..45210
                     /locus_tag="SCH06_000040"
     CDS             44203..45210
                     /locus_tag="SCH06_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEG1076652.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            45232..46251
                     /locus_tag="SCH06_000041"
     CDS             45232..46251
                     /locus_tag="SCH06_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1076653.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(46532..47899)
                     /gene="nhaC"
                     /locus_tag="SCH06_000042"
     CDS             complement(46532..47899)
                     /gene="nhaC"
                     /locus_tag="SCH06_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEG1076654.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFVFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(48009..49430)
                     /locus_tag="SCH06_000043"
     CDS             complement(48009..49430)
                     /locus_tag="SCH06_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1076655.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(49673..51550)
                     /gene="tdc"
                     /locus_tag="SCH06_000044"
     CDS             complement(49673..51550)
                     /gene="tdc"
                     /locus_tag="SCH06_000044"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEG1076656.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(51841..53097)
                     /locus_tag="SCH06_000045"
     CDS             complement(51841..53097)
                     /locus_tag="SCH06_000045"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEG1076657.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(53209..53414)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            53677..54978
                     /locus_tag="SCH06_000046"
     CDS             53677..54978
                     /locus_tag="SCH06_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEG1076658.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(55047..55646)
                     /locus_tag="SCH06_000047"
     CDS             complement(55047..55646)
                     /locus_tag="SCH06_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1076659.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            55900..56781
                     /locus_tag="SCH06_000048"
     CDS             55900..56781
                     /locus_tag="SCH06_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076660.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTVVEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            56794..58404
                     /locus_tag="SCH06_000049"
     CDS             56794..58404
                     /locus_tag="SCH06_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HEG1076661.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(58481..59140)
                     /locus_tag="SCH06_000050"
     CDS             complement(58481..59140)
                     /locus_tag="SCH06_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEG1076662.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(59423..60088)
                     /locus_tag="SCH06_000051"
     CDS             complement(59423..60088)
                     /locus_tag="SCH06_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HEG1076663.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(60235..60840)
                     /gene="dhaL"
                     /locus_tag="SCH06_000052"
     CDS             complement(60235..60840)
                     /gene="dhaL"
                     /locus_tag="SCH06_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEG1076664.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(60868..61878)
                     /gene="dhaK"
                     /locus_tag="SCH06_000053"
     CDS             complement(60868..61878)
                     /gene="dhaK"
                     /locus_tag="SCH06_000053"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEG1076665.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(61853..62299)
                     /gene="dhaM"
                     /locus_tag="SCH06_000054"
     CDS             complement(61853..62299)
                     /gene="dhaM"
                     /locus_tag="SCH06_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEG1076666.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            62402..62722
                     /locus_tag="SCH06_000055"
     CDS             62402..62722
                     /locus_tag="SCH06_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HEG1076667.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(62834..63703)
                     /locus_tag="SCH06_000056"
     CDS             complement(62834..63703)
                     /locus_tag="SCH06_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1076668.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(63799..65102)
                     /locus_tag="SCH06_000057"
                     /pseudo
     CDS             complement(63799..65102)
                     /locus_tag="SCH06_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(65099..65608)
                     /locus_tag="SCH06_000058"
     CDS             complement(65099..65608)
                     /locus_tag="SCH06_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076669.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(65783..67918)
                     /locus_tag="SCH06_000059"
     CDS             complement(65783..67918)
                     /locus_tag="SCH06_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1076670.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(68001..69656)
                     /locus_tag="SCH06_000060"
     CDS             complement(68001..69656)
                     /locus_tag="SCH06_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEG1076671.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(69658..69972)
                     /locus_tag="SCH06_000061"
     CDS             complement(69658..69972)
                     /locus_tag="SCH06_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEG1076672.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            70142..70402
                     /locus_tag="SCH06_000062"
     CDS             70142..70402
                     /locus_tag="SCH06_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEG1076673.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            70416..70730
                     /locus_tag="SCH06_000063"
     CDS             70416..70730
                     /locus_tag="SCH06_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HEG1076674.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(71460..72014)
                     /locus_tag="SCH06_000064"
     CDS             complement(71460..72014)
                     /locus_tag="SCH06_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEG1076675.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(72140..74068)
                     /locus_tag="SCH06_000065"
     CDS             complement(72140..74068)
                     /locus_tag="SCH06_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEG1076676.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(74374..75090)
                     /locus_tag="SCH06_000066"
     CDS             complement(74374..75090)
                     /locus_tag="SCH06_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEG1076677.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(75091..76914)
                     /gene="glpO"
                     /locus_tag="SCH06_000067"
     CDS             complement(75091..76914)
                     /gene="glpO"
                     /locus_tag="SCH06_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEG1076678.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(76928..78424)
                     /gene="glpK"
                     /locus_tag="SCH06_000068"
     CDS             complement(76928..78424)
                     /gene="glpK"
                     /locus_tag="SCH06_000068"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEG1076679.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(78560..80020)
                     /locus_tag="SCH06_000069"
     CDS             complement(78560..80020)
                     /locus_tag="SCH06_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076680.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(80010..81305)
                     /locus_tag="SCH06_000070"
     CDS             complement(80010..81305)
                     /locus_tag="SCH06_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEG1076681.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(81637..82314)
                     /locus_tag="SCH06_000071"
     CDS             complement(81637..82314)
                     /locus_tag="SCH06_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HEG1076682.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(82344..83435)
                     /locus_tag="SCH06_000072"
     CDS             complement(82344..83435)
                     /locus_tag="SCH06_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEG1076683.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(83536..83970)
                     /locus_tag="SCH06_000073"
     CDS             complement(83536..83970)
                     /locus_tag="SCH06_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1076684.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(84554..86011)
                     /gene="ascB"
                     /locus_tag="SCH06_000074"
     CDS             complement(84554..86011)
                     /gene="ascB"
                     /locus_tag="SCH06_000074"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEG1076685.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(86008..87903)
                     /locus_tag="SCH06_000075"
     CDS             complement(86008..87903)
                     /locus_tag="SCH06_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1076686.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(87961..89736)
                     /locus_tag="SCH06_000076"
     CDS             complement(87961..89736)
                     /locus_tag="SCH06_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEG1076687.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(89786..91282)
                     /locus_tag="SCH06_000077"
     CDS             complement(89786..91282)
                     /locus_tag="SCH06_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1076688.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(91476..93098)
                     /locus_tag="SCH06_000078"
     CDS             complement(91476..93098)
                     /locus_tag="SCH06_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEG1076689.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(93547..94860)
                     /locus_tag="SCH06_000079"
     CDS             complement(93547..94860)
                     /locus_tag="SCH06_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEG1076690.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGIAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(95105..95329)
                     /locus_tag="SCH06_000080"
     CDS             complement(95105..95329)
                     /locus_tag="SCH06_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076691.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(95349..95771)
                     /locus_tag="SCH06_000081"
     CDS             complement(95349..95771)
                     /locus_tag="SCH06_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEG1076692.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(95915..96625)
                     /locus_tag="SCH06_000082"
     CDS             complement(95915..96625)
                     /locus_tag="SCH06_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076693.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(96643..97140)
                     /locus_tag="SCH06_000083"
     CDS             complement(96643..97140)
                     /locus_tag="SCH06_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1076694.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(97177..97629)
                     /locus_tag="SCH06_000084"
     CDS             complement(97177..97629)
                     /locus_tag="SCH06_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1076695.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(97764..98369)
                     /locus_tag="SCH06_000085"
     CDS             complement(97764..98369)
                     /locus_tag="SCH06_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEG1076696.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(98819..99439)
                     /locus_tag="SCH06_000086"
     CDS             complement(98819..99439)
                     /locus_tag="SCH06_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1076697.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLCQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(99441..100310)
                     /locus_tag="SCH06_000087"
     CDS             complement(99441..100310)
                     /locus_tag="SCH06_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HEG1076698.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(100333..100740)
                     /locus_tag="SCH06_000088"
     CDS             complement(100333..100740)
                     /locus_tag="SCH06_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEG1076699.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(100759..102048)
                     /locus_tag="SCH06_000089"
     CDS             complement(100759..102048)
                     /locus_tag="SCH06_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1076700.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(102075..102377)
                     /locus_tag="SCH06_000090"
     CDS             complement(102075..102377)
                     /locus_tag="SCH06_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1076701.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(102402..104495)
                     /locus_tag="SCH06_000091"
     CDS             complement(102402..104495)
                     /locus_tag="SCH06_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEG1076702.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKVFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(104984..105748)
                     /locus_tag="SCH06_000092"
     CDS             complement(104984..105748)
                     /locus_tag="SCH06_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HEG1076703.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(105859..106728)
                     /gene="mdcB"
                     /locus_tag="SCH06_000093"
     CDS             complement(105859..106728)
                     /gene="mdcB"
                     /locus_tag="SCH06_000093"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HEG1076704.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(106753..107829)
                     /locus_tag="SCH06_000094"
     CDS             complement(106753..107829)
                     /locus_tag="SCH06_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEG1076705.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(107853..108446)
                     /locus_tag="SCH06_000095"
     CDS             complement(107853..108446)
                     /locus_tag="SCH06_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HEG1076706.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(108450..110126)
                     /gene="mdcD"
                     /locus_tag="SCH06_000096"
     CDS             complement(108450..110126)
                     /gene="mdcD"
                     /locus_tag="SCH06_000096"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HEG1076707.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(110116..110415)
                     /locus_tag="SCH06_000097"
     CDS             complement(110116..110415)
                     /locus_tag="SCH06_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HEG1076708.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(110517..112163)
                     /gene="mdcA"
                     /locus_tag="SCH06_000098"
     CDS             complement(110517..112163)
                     /gene="mdcA"
                     /locus_tag="SCH06_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HEG1076709.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(112170..113081)
                     /locus_tag="SCH06_000099"
     CDS             complement(112170..113081)
                     /locus_tag="SCH06_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEG1076710.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            113201..114058
                     /locus_tag="SCH06_000100"
     CDS             113201..114058
                     /locus_tag="SCH06_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1076711.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(114245..114607)
                     /locus_tag="SCH06_000101"
     CDS             complement(114245..114607)
                     /locus_tag="SCH06_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEG1076712.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            114953..116392
                     /locus_tag="SCH06_000102"
     CDS             114953..116392
                     /locus_tag="SCH06_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076713.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(116399..118951)
                     /locus_tag="SCH06_000103"
     CDS             complement(116399..118951)
                     /locus_tag="SCH06_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEG1076714.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(119065..120396)
                     /locus_tag="SCH06_000104"
     CDS             complement(119065..120396)
                     /locus_tag="SCH06_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1076715.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(120362..121840)
                     /locus_tag="SCH06_000105"
     CDS             complement(120362..121840)
                     /locus_tag="SCH06_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1076716.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITLLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(122145..123980)
                     /gene="tdc"
                     /locus_tag="SCH06_000106"
     CDS             complement(122145..123980)
                     /gene="tdc"
                     /locus_tag="SCH06_000106"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEG1076717.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        36523 a        26016 c        21725 g        39974 t
ORIGIN      
        1 attattataa ctgaacagaa agcgtttgta aaatttatct ttatacattc taagaggtct
       61 gttgcccaat aaaaaacaag agatcagaca tgtatttgtc tatcctcttg tttaaaatag
      121 caaaatattc ttgtttcttc tataaatggt gttcaaaagc ttttatctac ggcaatcagt
      181 cttctcaaat gtaaaacatg aggagctaat tttatttgag tattcttttt gctcgatgca
      241 ggacggcttt tttacaacct ctgattcatg gtgttcaatt agcagctgac cctcgttatt
      301 agctcaaaac gctgatttca caacctctgt ttttattcat tcgatttcaa cgcatcaatc
      361 atatcgatat gctttaattt gaaatgggta acaatcatca caataaccgt aaatacgata
      421 gttaatcctg ctgataagac ataagcccac catgtgatca ctaatggaaa gatgacattc
      481 tccatagacg cttgttgcaa gatgaagtca gtcaatatat atcctacacc aaatcctccg
      541 atgattccta aaagagtaaa gatgatattt tctcgaacaa tgtacatcgt gacttcttta
      601 tcaaaaaatc caaggacttt tattgtagat aattcgcgta cacgctcgga aatattgata
      661 ttagttagat tatacaagac gataaaagcc agcagtcctg ataatacgac aaagattaag
      721 acaaccgagt ctaagttcgc cattgattct tcttgcgttt cgatttgttt ggacatgaaa
      781 gacgtatttg tcacagcgtc tgtggcaagc agtttctcgg aaagcatttc ttcttctttt
      841 gttgtcatct tatctgtacg cagcaaaaat gcattatcca tcatcgattg atcagtaact
      901 gaagcataat attcagggga catataaata aagctaccta gatagttttt cacgatttct
      961 tttacttcga ctttccattc tttttgatct tcatcataaa gcgaaatatg atctcctgta
     1021 gataagtcaa atagttctgc tactttttgc gtaatagcga ttcctgtttt aggcaaggag
     1081 cgtgggttct cttcaagatc agttaaatgg ataaaacgat ccaaatcagc tgttttactt
     1141 ggtacgatca ctgtcagact ttgcgaagca tgtccttttt ttctcaattc tacggtttga
     1201 gtatgaatag ctaggatctc atttactttt tcttgcttct gcagcatatc cgctgctttt
     1261 tgacgactat cttccgtgga tgaatccaat gtaacgattg cttgatagtc aatgatcggt
     1321 ccaaattgtt tggctgaaac agaacttaga gaatctttca atcccacgcc tgcaaccatc
     1381 agcccggcac atccagcaat tccgataatc gccataagca ttcttgactt atatcggaag
     1441 agatttcggt aactgatttt ttgattaaag ctaaggcgtg accacagcgg agtgatgtat
     1501 tcaagaaaaa tgcgtttccc tggcttcggt gctttcggtt gaagcaatgc agcaggccgt
     1561 tctcttaaat ctttgaataa aacgatcatt gcagcgccaa atgcggcaat gaagaatgcg
     1621 gcagctgctt gtaaaatcgg cggccagtca taaaaaataa gcgcactccc aatatcatac
     1681 cgctcgttag acagctcaaa aatgatcctt ggcaaaagat tcgttcctaa tatcgttcct
     1741 aaaacaatac ctatccctga ggctagactt gcatagattg catatttttt tgcgatttca
     1801 actttcgtat aacctaacgc ctttaatgtc ccgatttccc tgcggttttc ttctaccata
     1861 cgtgtcattg tcgtaaaggt gatcaatgcg gcaataaaga aaaagaaaac aggaaaaaca
     1921 ttggcaatcg cagcgatacg atcagacaga tcaccaaatt cttgaaaacc gacattttct
     1981 gaacgttcat tgtataggta tgatggttta gttaaatttt caattttttc tgcatttcga
     2041 ttcaattctt cctctgcaga ggccagttca cgttctttct caactaattg cctttcttgt
     2101 tcagcaagtt gagcttcttg ttgaggtaat gtttgaacag cgattgttcg ttgcgcttca
     2161 ggaagctgct ggatagttgc tgactgttgc gctaactgtt ttttagcatc ttctaaccgt
     2221 gttcttgctt gcgttgtttg tgctttgcca tccgctattt tttgctgtgc cggttctaat
     2281 tcttcgttgg ccgatttttt cagctcttct aagcgttctt cgggtcgatc ttgtaaatac
     2341 ttttctgcct tttcttgatt ttgctccatt ttatctttgt aagctttgct gtacgtattc
     2401 aaattcttta cgtttgtaaa atcaagatat aagacagaat aaatatctgt tttaaaaacg
     2461 gattcaggta aatagacaaa ataatcgacg ctaccatttc cgacgttcgc gtatcctctc
     2521 tccaaattgt tgatgaacaa tggagaacgg acaaagcccg tgatggtata ctctttttct
     2581 ttcaattcat ctgaatcaat ctgataaata tcaccgattt tatacccttc atcttccgct
     2641 ttttcatcca atacaagctg gtttggtttt tccgggagtt ttccatcagt taattgtagc
     2701 ttgttctgct tgttattttt gttataagaa aatatttgaa tcacttcgtt tttgccagta
     2761 ttggaataat agatctgttt tcctgtttct acttttgcat ctgggatctt ttctgcttga
     2821 gcaatatctt tttgtgtcaa gccaccagta gaaacgattt gcaaatcaga aagtcctgct
     2881 gtaccaacat agtgatccat cgttttttgc atgacaggtc cagcagtttt gacacctaca
     2941 aataaaagtg ttcctagcat gacaataagg atgattgcaa tgaatcgtcc tttagattgc
     3001 cgaatttcgc gaaaacctgc tttaagatat gttcttgttt tcataaaatc cccctaccat
     3061 acaatctcat caatggatga aggatgatca tttaattcaa cagaccttac tttagcatca
     3121 ttaatgtgaa tgactctatc agcgatgggc gctaaagcag aattatgtgt aatgatcaaa
     3181 acggtattgc cgtgttgtct gctagcgttt tgcaataatt tcaatacttg cttgcccgtt
     3241 tcaaaatcca gcgcgcctgt cggttcatca cataaaagaa gtttgggatt tttagctagt
     3301 gcacgagcaa ttgaaaccct ctgctgttcg cctcctgata attgggacgg aaagttattc
     3361 aatcgatgag ctaggcccac ttgcctcaat acctctacag gatcaagcgc atcaggagaa
     3421 acttccgttg ccaattccac attttctttt gctgttagat taggaacgag attgtagaat
     3481 tggaaaacga accctacatc tgttcgtcgg taagcagtaa gctgtttatc tgaaaattgc
     3541 gcaatatctg tgtcatcaat aatgatctga ccttcatcag gtgtatccat cccacctaaa
     3601 atattaagaa tcgttgactt tcctgctcca cttggaccaa gtataatcac taattcgcct
     3661 ttttcaattg aaaaagaaat atcgtcattt gctgtaatgg tcgtttctcc cattttgtat
     3721 cgtttgtatt cattttttac ttcgacatac ttcactctga ttcctccatt ttcacgatat
     3781 ttctcgctat atctatgcat cgaatgcgtt ttctcacact tatttatttt accactgaat
     3841 ttctctagac taaagaaagg aatcctttaa tttagttgac aaataaacga tttatgattt
     3901 acttacataa aaaacattgt tatttgaaag aaggaacatc atgaatgatt taaaggaaaa
     3961 tatgattttt gatttatcaa aaactgcttt tgtcgcgatc gacatgcaaa aagagatcgt
     4021 aaataacggt acactctctc cacacactgc agcatctatt ctgacaaaca atgatttgtt
     4081 agtaagaaca ttgaaacgta ccgctgcctt gaaagtttta gtgaacgtag acatctccac
     4141 tttcccttat ttgagtcaac aaactgatat gggtggaatg actgcttctg tacctccaga
     4201 attcactgat ttacttttga aggattcttt gaaagataca gataatatgt tgactatcaa
     4261 aaaatacaat ccaagtgctt tttttggtac ttctcttgat cttcaacttc gccggcgtgg
     4321 aatcgaaact atcattttaa gcggtgtagc gacaacaaac ggtgtatatg ctactgcatt
     4381 agatgccttt caacacgggt accatatcgt gcttgctgaa gatgcttgca gtgatcgtga
     4441 caaagaatcc catcaattgt tcataaaaaa gatatttccg aaaactgcac gagtacgctc
     4501 aacgaaacaa ataatcgaag ctatccaaca aagcaaataa gtactggcac acgtgatttt
     4561 catttacttc tttttgattt catgggaaaa taaccacagg atttagatag gagtatgaac
     4621 atggtgaaaa aaaagatcac aatcaaagaa gtcgctaaac tttccggcgt ttcaatcaca
     4681 actgtctcct tgatattaaa tggaaatacg gagaaattca gtccgaaaac tgttcagaaa
     4741 gttttagctg ccaaagaaga attaggctat cagcctgact attttgctag acaaatgatt
     4801 accaaggaaa cgaaaacaat tggtgtactc gttcctgata tcacgaatcc attcttcagt
     4861 acactgatgc gaggaattga ggatatcttg tataagcaga atttcgtcac gatattatgt
     4921 aatgctgatt ctgatcatca aaaagaaatc gaatatctag ccgagctcac acgtcgaggt
     4981 gtggatggat tcattatcgc gacttctgct gtctctacag atgcaatcaa cgaaaatttg
     5041 aaaaaacaag gccggccctt cattgttttg gatcagaaaa aatctgaagg atttagtgat
     5101 gccgtacgaa cagacgattt tcgcggtggt tacctagcgg gcatgcactt gcttagtcta
     5161 ggacatcaaa cgatcgccct tgtctatcct gaaaatccac cggaaaatgt ccacgctcgg
     5221 attgaggggt ttaaatctgc tcttgatgtt taccaaatcc ctcacgacca actgatcctc
     5281 ttacctacac agttctcaaa acaaggtggc taccagatca cagcagaact tcttgattct
     5341 gctgcaactg gtgtgtttgc tttaaatgat gaattagctt ttggattata tcgcggatta
     5401 gaggaagctg gaaaaagcat ccctgaagac tacagcatta ttggctatga taatatagat
     5461 atgtgcgagt atatcaagcc gaaactgaca acgatcgcac aaccaatctt cgaattggga
     5521 caaacatctg ccaagttatt gttagatcgg atccaattcc cagaaaaaga atgggaagaa
     5581 aaaagattac ctgtacgatt agaaaaaaga ttttcaactg cacccttgaa atagctttca
     5641 aggtgtgcta tatttttatc gaactattaa aacgttttac taaaacgttt taaaaaataa
     5701 ttttcccatc aaaataaatg agatagttgg aggtttgtaa aatgaacacg gttacagtaa
     5761 ttggaagtat taatatggac actacccttc gtttaaccaa catgcccaag ccaggcgaaa
     5821 cgatgcatgc gcatgagatt tttcacgctg gcggaggtaa aggtgccaac caagcagtgg
     5881 cagccaaacg ttcaggcgca cggacatctt ttattggagg cgttggggct gacagcgaag
     5941 gacaacagtt attagatcta ctgacaaaag aaaacatcga tacatctggg atagctgaaa
     6001 tccaaggcgc cacaaccgga caagcaatga ttatggtaga cgcagcagga gaaaatagta
     6061 tcttgatcca tgcaggggca aataatgctt tccatgaaca agaagtccta aaaaacaagc
     6121 aactgattac aaacagtgac tttattattg ctcagtttga aagtagctta gatgcgacga
     6181 tcctagcttt ttctattgca aaagacgcag gaaaaacaac gatcctgaat cctgcaccag
     6241 ctcgtgaaac gattcctact gaactacttg aaaagacaga tatcattata ccaaatgaaa
     6301 cagaaacaga aatcattaca ggaatcagag tgacagatca taacagtttg gtcgcagcag
     6361 ccgaaaaact ccatgaatta ggtattggaa cagtaatcat tacactaggc agtgccggcg
     6421 ctttctatca tacagaaaaa gaacacggta tcgtccctgc ttttaaagtg gatgccgttg
     6481 acacaacagc cgcaggtgat acatttattg gcgcattaag cagcacactt cagccagacc
     6541 ttagtaactt gaaagaagcg atcctttatg gaaatctagc ctcttctgtt gctgtgcagt
     6601 cttatggtgc gcaaccttct atcccttacc gcgaagcttt agaacaatca gcagtctaaa
     6661 attaacaatg agaggaagaa acaaacatga aaaaaggaaa agtaatcaat tcagatattt
     6721 cacgagtaat cgcacaaatg gggcactttg ataaattaag tatcggggat gcaggcatgc
     6781 ctgtcccctt tggtactgaa aaaatagatt tggctgtctc aaacggtctt ccaagttttt
     6841 tatctgtttt agaaaacgtt ttagaagaac ttgaggtaca atcgattgaa ttggcggaag
     6901 aaataaagac aatgaacccg gaaatattgg aaaaaatcaa attattgtta ccagatacac
     6961 cgattagctt tatcccacat gaagaaatga aaaaagagtt gaataactgt catgcattta
     7021 ttcgtacagg cgaaatgaca ccttacgcca atattatatt agtgagtgga gtggtcttct
     7081 aatggaaacg acaatgaatc ctgaacagat ggtactgtcc gagcagattc atatgctgat
     7141 tgaacagttg ggaggaaaag acaatattga ttctgtcctt ccatgtgcga ctcggcttcg
     7201 tatcaaattg aaaaaacagc cagtagccaa tgcagaaaaa ttaaaacagc aaatcccttc
     7261 cattaagtat ttcattttac tcgatagata tgcagaaata atcatggatc agggattggc
     7321 tcctgcttac aaggaattga cgcgtcaaat cgatcattca gctccgaaag aaaagctaaa
     7381 tccgatcgaa aaactatttg gtttgatatc ggaaatcttt acgccgatca ttccgctgtt
     7441 tgccggttct ggtatattaa aaggtctggt tgttttagcg actacgattg gctggcttag
     7501 tgaaacaagc ggaacttatc atattttgtc tgctgcgtcg aatgccgtct tttattttct
     7561 gccaatcttt cttgcttttt ctgctgccaa aacgtttaaa gtgaatggat atattgcggc
     7621 tgtcattgct gcagcactga ttgaaccgaa tctgacctct ttactttcag acagtggcaa
     7681 agcagctact gattttctgg ggattcctgt agtactgatg cagtatacgt ctactgtcat
     7741 gccggcgatt ttaggtattt tcttttattc ttttgttgaa aaattcctca aaaaatatat
     7801 tcgcgaaaat atgcaattag tatttgtacc tttactttca ttagttatca cggttccttt
     7861 gacgttaatg gtattcgggc ctgcgggtgt ttaccttggc gaaggtttag ctgccgcaat
     7921 tacttggatg atggatatta acggaccgat cagtggcgca atcatcgctg gtggttggaa
     7981 tattttggta atatttggta tccaatgggc tgtaaaccct gtcatgatca gtaatatctc
     8041 tgcttatggg ttcgaccgaa tcgttccgtt gacaggagca gccaattttg gaatggctgg
     8101 tgcagcttta ggtgtatttc tgcgaagtaa acgttcaaaa acccgttcga tctccggttc
     8161 tgcttttgct tcgattttac ttgcgggagt gaccgaacca actgtttacg gaattgcgat
     8221 cccattgaaa aaaccatttg ttgctgcttg cattggtgca gctgctggtg gagctgtaat
     8281 gggatttgcc caagtgaaag cgatcgcttt tgtatttggt agtctgacca cattgcctgc
     8341 attcatttcc ggtacttttt tctggtactt agcaggactg gctgttagtc tagtcgtagc
     8401 aatgatcact actctcgtta gcgggtttga tgaagaccta atgtcttatg aatagttaat
     8461 gaaaaagact gaagtatgag atgtttatca catatttcag tctttttctt tttaggatca
     8521 ttatttttat aaatttttgt gatactttcc aaactttggt ataatttaca tatgcataac
     8581 catttttatc cccacttgtt tatccccaaa caaaggtggt ctatgcaata aaatgaacgt
     8641 caaagaaaaa cgaatgaatg ctcgttgctt atttacaaat tgttttattt agaatacaca
     8701 gacagattta tgaaaagaaa aagcttttcg acacgattat ctgttccaaa aaatgtctaa
     8761 tgaatgctga ataagacaga aaatcaatga aaggaaaagg actagtttat tatgaaaaat
     8821 aaaaaaacga tacgtttgct agctgctact tggctgattg ctccgtctgt tttgtcgacc
     8881 aataccgtat ttgccgtaga taatcaaata gctgatcaaa cagtcacaac agatacgact
     8941 acatccagct cagctactag tgaaacaacg gattctttta cagaagaccc aactggaaca
     9001 actaactcaa caacaggatc gaccgagcca actgaaattg atccggctga tccatcagaa
     9061 aatgaaaagc cagccgagac atattccctt acaattgctc cttctttgat tggtaagatc
     9121 caactgactg cttcgacagc ggattcccct gaacagcaac ctttggatat tacggaaagt
     9181 ggaacggtag aaggtttatt agcggaaacg aaggtaactt acactattac gccagctgaa
     9241 ggtgaacaaa ttgcttcagt cgctgttaat ggtgccaaag aagtaaatta tgatgcaaag
     9301 acctttacag taggtacgaa caatttatct attactgcag aatttaaagc tggaccggat
     9361 acttcaacag agaaaccaac tgatcctagt gaagaagtcc ctagtacacc agatccggaa
     9421 acgccaaaca aaccagatgt gggtaataac aacaataata atggttcaaa taattcaaac
     9481 aataataaca ataattcgaa cagcgggaat tcttcgaatc aaacaaaccc atctggatcg
     9541 aataacaatg gaaatactca gagagaacca aaccatccaa acaatggttc atcgaatggc
     9601 ggaacgaaca atgcttcatc tcgtccaaat acagcaaatc aaagcggtat agagaatcca
     9661 tcttctgctt cttctgattt tgttgtaaaa tcaccaattg atgctgtatt gcctacaaat
     9721 acaacgaatg tccaacaagc aatcgttcga gaagcattca agcatcttgg aaaaccatat
     9781 gtatggggag caaaaggtcc aaatactttt gactgttctg gtttgactta ttacgtatat
     9841 atgaaagcaa ccggtcatta tatcggtggc tggacaggcg aacagcaata tgcaggtacg
     9901 cagattccag taagtcaggc ccaacctggc gatctcgtct tctggggacc ttcttccggt
     9961 gttactcacc atgtaggtat ctatattggg aacggacaat ttatccatgc gcctcaacca
    10021 ggagataaag ttcgagtaac ttctatttca gatttcacgc ctgattttgc tgtccgagta
    10081 aacttagcag gtttacctgc tgcttcaggt tcgctgacag gcggctcatc tattttagat
    10141 ggattagatg gctcgttcca tttcagtcaa aaccaaacaa ctgatcagtt cttgaaaaag
    10201 attgcagatg atgcacagga aatcgggcaa aaagaaggaa tctacgcatc agtcatgatg
    10261 gctcaagcta tccttgaaag tggatctgga aacagcttat tatcaagcga accaaatcat
    10321 aacctttttg gtatcaaagg atcatataaa ggaagcagcg tgaccttcaa tacacttgaa
    10381 caagatagtt ccggacaaag ctaccaaatc cgcgcacaat tccgtaaata tccttcttac
    10441 aaggaaagtt tggaagacta tgccgacttg atcaaaaatg gactgactgg caatcctgat
    10501 ttctacaaac caacttggaa gtcggaaaca aaagactaca aagaagcaac caaatatttg
    10561 gaaggacgtt atgctacaga tcgccaatat tcacaaaaat tgaacgcgat catcgaagcg
    10621 tacgacctga caaaatatga tgaaccgaaa aaagaagcag caacaactga agaagcaaac
    10681 gctgaaatcc tcaatatgtc taagcgattc gatgtgccaa tcaaatggac aacagatggc
    10741 gtgccaatca caggattaga attttcaacg ataaaacgcg tcaacaacgc ttcttccatc
    10801 ttccgtgtcg cttcaatctg ggatttgtgg aacaatttta cggcaagaca gataccagaa
    10861 acaactactc gtacagttaa agctgcaact gttcctgtac taaccttgtt aagtttagac
    10921 aaatcattct ggcttgatct gcctttaaag aaatagaata aattaaaaag gggatgtgac
    10981 actgtcacac tcccttttta atttattcta tttctttata tttattttgt attccgttac
    11041 aaactcgcgt acttggttag gttccagagt gacatctcca aaactttcaa gtcgctccgc
    11101 tcctggcagt tcttgagtct caaatgtgat accgccatga tttactaatt tattcccgcg
    11161 catttccggt ccatcttctc caaaatttgc tgtaaaaatc acgattcctg aagcatctgt
    11221 ttttacttgg atcgatactt tttcatctgg gcttgtcaat tccgcagcat ttagtaaacc
    11281 agattgtttt ttcaacaaaa atggatgatc gatgccgccc actatcattg attggcgaaa
    11341 atcactggca aagacctcac ctaatttttt aggacgttgg aagtcaaatg ctgtgccact
    11401 tactgaaact acttctcctg taggcgttgt atctttattg agcgtagcaa ataatcggct
    11461 attcaaccaa agtatatgtt cgtcgattga ctgtgctgga tcaccggtta aattgaaata
    11521 gacatgattt gtaggattga atactgtttt gcggtcactg atcccttgga ccgtcactcg
    11581 ccatgtatca tcgttcgtca gcgtataccg tacttctaca tctaaagttc caggaaatcc
    11641 gtttcccata tctgggctag tctgatagaa aatgaccgat gcttcgtttt caccattgat
    11701 gactgtataa tgccactgct tggcttcaaa gctaggtgca ccaccatgta aacaatgacc
    11761 agtgtccggg tctgttttta cttcgaacgt ttcatcatct aatttgaatg tgccattcgt
    11821 aatccgtcca gccatacgtc cgattgaagc accgatataa gggtcttttt ctagatattc
    11881 ttttgcttca tcaaaaccta agatcaactc tcgtttttca ttatcgatta ttgtttgaaa
    11941 atgaacaacc cgtgccccaa gatcactgac agacaaagat gtcccatttt gattcgtgat
    12001 cgtaatcaag tgatagtttt cgccaaaatt ttgttcattg atttccatgt tccttgcacc
    12061 ctcttttctt tcatttgcac tgattccagt atacatggaa accgttttct taacagctta
    12121 ttccgtgagt aacgagaaaa aatttactat attctaataa aagaccgtga aaaaaaggtt
    12181 gtgacaaaaa tattgtcaca acctcttttt ccgaacaaac ggtgttcaaa agcttgcatc
    12241 tgcggtaata agcccaacca aacgaaaaat atgaggagct atttttgctt ggctgttctt
    12301 attacttgat gcaggacagc tttttcacaa tctctttttc aatacgattc cagtatataa
    12361 ccatgtcgtc agtacatagt agatgaaata caatacgaag aagatcgtaa acggaaccca
    12421 aatatctttg tatggatttt gcatgaatag accaaacatt tgtaatccga ataagacatg
    12481 gactacacct aagattcctg gtgctaagaa taacacgcct acttctctac ggatcgattg
    12541 tttaagcaac ccgcgtcgtg ttcctatctt ttcaagcatt tcataacgag caatgtcact
    12601 cttgcttcct gacaagatct tgaacatcaa acagctagca agcatggtca agaaagctaa
    12661 acctaggaag aatcccataa attcaaaacc agagaataga ccattataca cttcatacat
    12721 ttcatatttc tggttgctgt actctacttt ttgcaaagat ggattgttca ttttattttg
    12781 agcaacaagt gtttcgattg gtttcaggtt tgcttggaag tcttttacct gaactagctg
    12841 taaagtggat tgtggcaagt tcagttgatc aaattctgat tgactgacta ccttgatttc
    12901 tttttcttgc tgttccggca attcatagct tcgaagttcc tcttgtacag tcagttcatt
    12961 cattttttta gcaggaactt tttctttcgt gatcttcggc ggtgttccat cttcatgttt
    13021 tatcatgatc aatggttgag ccgcaaattc acttgcatta tagtaaatcg ttcccgcatc
    13081 ttctttttga gtataagaag cagaaagtgt tggtgaaagt tctttgattt tttgctgatc
    13141 ttctgcccga ggattattca tcactagatc atatccagaa ttgttttctg tcaagtctgc
    13201 aatttcattt ttaaaaccta atcctaccgt caaagcgccc agtgccaagg caaacagcat
    13261 agcgaccatt gagagcattt gtgtatattc acgaatacga aagtttaact gtgacaatgt
    13321 gaaattgttc aattttttca atgaaatctg ttctgatttc tttagtaatg ataaaaagaa
    13381 aatgatcaca gaatggaaaa tgaaataagt tcctaatatg atcgtaacta aggctacccc
    13441 tataccaaag acttgatagg tccccacgtg tttcatcata tagtaaccgc agcctagaaa
    13501 agcaattccc agtactactt caaggaaaaa caagaattta tgctgcttga ttcttgttgg
    13561 tgtctgatcc gcacgaatca atgctaaaat cggttttttg acaatcgaaa aagcattgac
    13621 aacagcagct aataaaaaca aaacagcaaa aaacaaaaca gtgatcaaca acccgtgaat
    13681 actaaaaggt gtaaaatgcg aaatattgag atctaactga tccactaata atcggtggac
    13741 gatacttgtc aatcctacac cgacagctga acccactaaa gtagctgcga tccctactaa
    13801 gaatgtttca gaaaaaatca tctgtgcgat ttttctgcct tttgctccca gcatcataaa
    13861 cattgcatag tctttttgcc gcatcgtcat caaaaaggaa tttgcatata aaatataaac
    13921 gaatgtgatg atccctagta aaacagaacc gaatcggaaa atgataactg tagccgcaac
    13981 gatcgtatta cttttcaaaa aagcttcgtt gcttgccatt gattcaaaca tgtaaaaaat
    14041 agcagatgcc ataactaatc ctgagaataa caccaagtag tctcttaaac ggctcttgat
    14101 cccagtaagt gataatttcc aaagcatagt caatctcccc ctactgttcc aagtttccaa
    14161 gaatagatag tatttctcga tagaaggaat cacggctttg atctccacgt ttcacttctt
    14221 gatggatacc gccatccttg atgaataaaa tacgttggca ataacttgca gaaaacggat
    14281 catgcgtcac aagaagaatc gatacatgat cttttgtatt caattcgtcc atcgtatcta
    14341 aaagatcccg ggcacttttg gaatccagcg cacctgtagg ctcatcccct aatagaatcg
    14401 ttggttgtgt gatcaatgca cgtgcggcgg cgacccgttg tttttgtcca ccggaaatct
    14461 cagaaggata gctttccaaa atatgagaga tggataaacg ttctgcaatt ttttggacac
    14521 gttgcttgat ttcttttggt ctgacgcctt gtaaagaaag aggaacagcg atattttctt
    14581 gtgctgtcaa gctttctaat aaattgaaat cttggaaaat aaagccaatc tcattcgcac
    14641 gaaaatctgc tagttgattt ccttttaatg tggtcacatc tttttgattg attcggatat
    14701 gcccatctgt tggtttatct aatgtggata aaatattcaa aagtgtcgac ttaccagaac
    14761 cagaagcgcc catgatccca ataaattcgc ctttttctac atcgaagctg atgccgctta
    14821 atgcttgcgt ctttttctca ttgttttttc cgtatacttt tgttacattc tgtacttcga
    14881 ctattttgtt catttctttc cctacccttt aattagtttt tccagtgctg ttttcggcac
    14941 gtcttttttt tcgacttctt catacgaagt gacaccttta tttttgttcc aggtgatttt
    15001 taaatatgct cctttacgaa gcggtcgagt caattgtccc ttgaagtcca gttctttttc
    15061 cttaccctct ttcgtatagc caggcaggat atatctatag ttgactgttt cttgtccaga
    15121 gtctgatttt gaaactgttt ttgtaccatc tgtcgtaatt tgtacatagt attcttctcc
    15181 acccataact acgtaatctg cgattttcac ccctgcaagt accacaacga tgaaaacaag
    15241 tagaccgatc agaagttttt tcactttttc cccttctctc ttactttata tactgattat
    15301 agaaaaaagc gaacaattct gccttcgaat caactatcat tcttctttca attttgtcat
    15361 tttctttaaa acaactaaaa aaagagttca agacaataat ccgtcctaaa ctccttcttc
    15421 ctatcttaca aaaagtatgt cacttacggt ctttcatgtc gcctgtattg ataacaggtt
    15481 gcgttccttt gtctgtaatg attgagacaa gtaaattatt gatcaattgg actttccgat
    15541 catcggtgaa attgatttct tgtccatctt cgatttgctc taaggccatt tgagtgattg
    15601 tgacagctcc ttcaacaatg gtttgtcgag cagacaaaat ggcttttgct tgttgacgtt
    15661 ggagcatggc actagcgatt tctgttgcat aggctaaatg gttcaagcgt gtttcgatta
    15721 cttcgacacc tgctactgct aaacgctctt gcagctcttt ttgcaactcg tcagacactg
    15781 ccgtcgtgtt tcctcgaagc gtcaaatcat tctcattgaa tgtatcatac gggtattggc
    15841 tagcgatatg ccgaatggct gtctcacttt ggatttctac aaaatcttga taatacgcta
    15901 catcgaataa tgcctttgct gtatcaacga ctttaaagac tactactgct gagatttcga
    15961 tggggtttcc atccaaatca ttgactttta aaacagaact attgaaattc cgaactttca
    16021 acgaaacagt cattttttgt gccaaaggta tcgtaaggaa aaagccattt tctcgaatcg
    16081 tacctaaata ttgtccaaaa aacaaaatta cttttgcttg attaggactg actacagttg
    16141 ccgaacttaa caacaataac gtgatcaacc aaagaaaaat acttaaaaaa agtgcccaaa
    16201 ctttcgcttg ccacatacct aaatagaaga aaaacaatcc aactaaagct aatacgacca
    16261 atccgacaat ccctgcataa ccattgatat aaaatgctct tttttctctc atgctacttc
    16321 ctgcgctcct ttatccttca ataaatatct aatgttactt ttttaatttt ttttcgaata
    16381 cgcgccatta caccttctag ttctaactct ttgtcttcag tgatgtacca accccttgcc
    16441 tgtgtccctc cggctgcctg cggtaaataa tccaattttg ttcgaaccca gtgcttttct
    16501 tctgtaaaat agtcttctac caagacctct agatccatcc ctgctgaaag aggcaaatct
    16561 tcccgaacag atttaaagat aaatcgttcc ttcttcccat catacttcaa tattcctgta
    16621 tcgataatcg gtaaagaata ataatccagc tctttcttca ccgtcaataa atgtttgaaa
    16681 acttcatggt acacttgctc taattggcga ccttctgaat tgttcgggta attaaccatc
    16741 actttttctt tgtctggatc atagaaggtt tggcttagtt gagtgatata agtatgtaat
    16801 ctttccattt ctgtttttaa cttttctctt tgaccttctt ctaccttcat atactctttc
    16861 accctgtttt ctttttagat attttctttc ttattttact atagttatgt gcgttaagcg
    16921 atgaaaaaca gcaaagattg gaaggatctt tgctgttttt tcttaaaata tccagttgag
    16981 tacaggatca atctgtttca ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt
    17041 tagcagtgat ctttagcttt ttctgtcctt gttctaacaa agtatttgtt attggctggt
    17101 agtctttttc aatataagat tcaccagacg tttggatagt atagccactg ttttccatct
    17161 catgcaaaga taaattgcca ccgtttagga tgacttttcc ttctttgctg atcaaactgt
    17221 cttctagatg gaagttgctg ttttcacctg tgacgatcaa gttatccaca ttggcctcat
    17281 ctaatcgaag tgagcctaat tcatctttcg cagttattgt tcctcctgta aattcattga
    17341 acgataccca gccatcatgt gtcttagtat tcactttttt gattgatact tcgttgatat
    17401 caattgcact attattccct tcgattgtca attcagataa ttcatgatct gcagggacaa
    17461 caatagtgat ttgtgcactt gtgtcttcta aactaatgat tgcacctgtt gattttttga
    17521 ctgcattcac agtcaacacg ccatttttct cctttatttc tggcttttct gtcttatcat
    17581 aagtcgtttt tatctcaaaa tccaatccgc gtatgaccga aactgtttga ttttctgcat
    17641 ggatgacgat tttgtttgca tccttgattt tttttgtctc agtaaccata tcgatcaacc
    17701 gaggaccatt atcccaagtc agactctttt gagcgcctaa tgtataagtt gcacctgcta
    17761 ggaggccacc agtaagcatc agaccaatac cggtaatcaa aaaatgtttc aatctcaatt
    17821 tatgtgtcct ccttcaaacg cccgctgaat gcagatctct ttttgtaata aaacgtcgtc
    17881 ccatccattt aacaaagttc atcatgacat aaaaaagccc ttttgttcct ttcagcaaca
    17941 gtggcgaaat aaatactgcg cttcctgtgg cgaacagacc gacaccgata aagaataatc
    18001 cactcagaat cgattgtcca aacacactga ttcctgagat gatcatgaat aggccaacac
    18061 ctaagatact gatacataaa acatagatac taaaaatgag cgctagtaaa gcaaccaata
    18121 gtcccccaat aaccaatata aaccccagtg ctagtggaat gaggacagga gaagcaaata
    18181 aaccgataat gattaaccaa atcaggcgaa tttgtctttt tggatttttc actaactcgt
    18241 tttctgcttg ttcttcttct gaaaagtaac tgatttttaa ttttaaggca aactgctttg
    18301 gtgtaccata ttcatcaatg atctgatcta atgtttttcc agaatctaaa aaatattcct
    18361 cataatactg gatcaaatca aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa
    18421 cttcattcaa atattcattc atttgtgctc tcctccaata accggtctaa agaatctcga
    18481 aaaacaatcc attcatcaat aatttcttct aaatgacgac ttcccattgg tgtcaacgag
    18541 taatatcgac ggtttctgcc ttcaaaaggt tcatcatagg tctcaagata tccttctttt
    18601 ttcaatcttc tcaaaaccgg atatagtgta gattcactga cagagagact ttcttgtacg
    18661 atttttgtta aggcataccc atacatatct tccttgctta atgctgctag cacagtacca
    18721 tcaagaagaa cagttggaat ctggatgtgc attacgtcac cttctattct caagtgtaat
    18781 attttatttc aatctatatt atacaacata taatatagtt tcaaaatcag tttgtcaaat
    18841 acaaaaaaac tgactaaaag atttgatcct ttttagtcag caaaaaatgg cttctctttg
    18901 atttttatta taacagtggc ataatccaat ttgtccacat ccagctcagt ggcatgataa
    18961 cgatcattgc aggtatcatg tcagctactg ggaacatttt cacgttgatc attctaaaac
    19021 cggtagcgac catcaagaat ccgccgcaag ctttaaaatc taagatcatg tctggtgtag
    19081 tcaatggata aataaatttt gccaataaga acaaaatata aaaaataatg aattggggaa
    19141 ttgctatcac agaaacgaca taccctaaat tacacgcaaa aatagctgct gtgaaaaaat
    19201 caaggacaga tttagaaatc aaaatcgtac tgtctcctgt catcccagaa tctaaacttc
    19261 catagatccc cgtaccactt gcacaaaata gaacaatgac cgtcactaat gtgctgataa
    19321 attcatcgtg ggtcatacca agcttttcac tagggaagat tttagaaata ggtacttgca
    19381 tcagcgcagc ccccttattt atcccattac ctaaatgaac aatcagacca atcgctgttc
    19441 ctatcactaa agcaaaaata acagccggca tatttttcat cggcgcaatg gaatagattc
    19501 ccatccccat cgaacacaca ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta
    19561 atttatttcc tactaatccg ccaattagtc cgccaagcaa aacggaacct acattgatca
    19621 aaactccagt tggcatcaaa aaactcctct ctttttctac gaagcgaaaa aaatcagaaa
    19681 aatttctgta attattgctt tcgctgcaag aaagattgta acagacagag aagattacac
    19741 caattcattt tttgtgttaa agtattcttt attggaataa gtaggaggaa tatgatggat
    19801 atccataaat tcgaagtttt tcttgattta gccgaaacaa tgaatttcac caaaactgct
    19861 gatcgacaat tcaccaccca aggaaatatt tctaaacaga ttctttcgtt agaaacagaa
    19921 ttagacgtca aattattcga acgcgcccat agaaaaatcg aattgaccga agctggaagc
    19981 ttattgctcc catatgtaaa aaatgtcgta gaacaatacc atgctatgca agaagtgctt
    20041 gaaacctata cgaaagacaa caatctttca ttaaatatct taacgatacc gacaatgatc
    20101 aattataaag gtttttccaa aatcaccgag tttttgaaac gccatcctga atttacagtc
    20161 cagttgaaag aagtggaaag tgtcgaatta acttacaatg acgccaatga acatagtgac
    20221 acgatccact ttgctagaaa tttccaggcc ccaccaagtt cgattgagtg gttgcctact
    20281 gaaacagacg attttgtagc agttctacct aaaaatcatc ctttagctag taaaaagaaa
    20341 ttggatctaa gcgaactgaa aaaggagaac tttttgctcc ttggccccac tacgaacttg
    20401 tatcaacctg tactagatct gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa
    20461 ggagcaagaa tcgacttgat catcaatatg attgcaaatg acatggggat tgctattgtt
    20521 atggaaaaaa cagtcaagaa tctattaaaa gaaaatactg tgattctccc tatttctcca
    20581 acaacagaga gttatcttgc atttactcgt aaagtcggtg agcattcttt ggcttcagat
    20641 acattttggg agtatttaaa tcaagaagaa aactaagccc tacattttct gtccatctat
    20701 ccacccaaaa aaagagagcg acgcatgact ttcgctctct ttcttgcatc atgtccttgt
    20761 ttcaatgaca cctctaacat ttctcgtagt tcaataagaa agcagcgatt tttatgccaa
    20821 aagaaccgta agaacatttc cctaatcaca aaaaaacgac taaaaacccc taaaaacctt
    20881 caatagaatt tttaggggtt ttattctttt tcctattgtt tacttaaccg tatcattgct
    20941 gtcgttccta ctccttcgat actgctataa tcaatacgtc catcatgcag ttctagaatt
    21001 tttttaacca gtgaaagtcc tagcccattc ccagaaattt gacgacttgt atctccttga
    21061 taaaattttt caaacattcg atctctggtc tcttcattca ttcctacacc tgaatcggtc
    21121 acttccagtc caatctctgt ggctgtctca aatagtttga tatgaatctg tccattgatt
    21181 tgattgtact ttatggcgtt atccatgata ttcagccaca cttggtacaa aaactcttca
    21241 ttgcctgtgt aatttactgc agcaagttcg atatccaatt ctagctgttc tttctcccat
    21301 ttaggctgca aaaaaacgat tacttctctg atttgttcat ctaatcgata ctctttcttt
    21361 tccagttgga tacgctggtt ttccagtttg ttcaatttta agatgttctc tgttaattgt
    21421 gaaagctgcg tgatactttc gataatccga tataaaaata tttggcgttc ttcgtcagag
    21481 agatttgggg cttgtaacaa ttgaacatat ccttggattg ttgctagtgg tgttttgaat
    21541 tcatgggata cactggacac aaagtcattc ctcagtgtct cgatactatt gagttcttgg
    21601 accataacgt tgaaatcttt atacagttgc tgtacttctg ctactttctg ctgttcatcc
    21661 attcgaatcg aaaaatctcc cgttgctacc agactcatat ttgtccctag cgcactgatt
    21721 ggatgcagga tacgccgccc aacaaaaatc gatattcctg tacccacgac catactgaac
    21781 cccgcaaaga cgaataacgg gtataacgtt ggttttccag ccgattcagc aggcgagata
    21841 gaatgtcgag acaataagaa aataaaaccg agaaaacaca gcagtgtcac taagatcgaa
    21901 atgaagacaa tactagcaaa atagatccat aattgtgaaa atagcttttt tttcatcttt
    21961 aaataaccgc cttatagcct agtccccgta ctgtgatgat ttgaaaatct tccgtctttt
    22021 caaaacgggt ccttaaacgt ttgatatgta catcgatcgt tcgttcttct gtattcgtat
    22081 ctaatcccca aatatcatcc atcaactgtt ggcgagtgaa gatcttgttg ggataagaca
    22141 gtaatttata cagaagcaga aattcttttt gaggcagaat caacgaatgc tgatcttgta
    22201 acactgtata agcatctagc tctaattttg tttgtccgat tatcaagcta ctgctgtaat
    22261 tgatctttga acgtcgaagc aatgcttcca cacgtaggat catctcattg acatcgatgg
    22321 gttttgtcat ataatcatct gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg
    22381 cctttgccgt aatcattaga acaggtgtgt caaatctggt gctacgtaat gagtctagca
    22441 agtcatagcc atccattttc ggcatcatga tatctgtaat gattaattct atacgtgtcg
    22501 cttctagttt tttcagcgca tcctctccat tcaatgcggt gatgactgaa aagcccgctc
    22561 gttccaacac agaacggtaa agcaactgta attgcggatc atcttctact actaaaatac
    22621 gattcattga tctccctctg ttttttgaaa aatttctaga ttttttcttg tagttcatct
    22681 tcagttaaca tttatttcgt atactacgat cattgttctg atatacttat tagtataccg
    22741 aatatttcaa tacgggagaa gggtgattat gcttcaatta aaagatataa aaaaatatta
    22801 taaagtcggc gaaaccacca ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa
    22861 agaattcgta gcgattttag gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat
    22921 tggtggacta gataattatg attccggtga tatggtaatc aacggaaagt ctactaaaga
    22981 ctttaaggac agtgactggg atgcctaccg aaacaactct atcggtttca tttttcaaag
    23041 ttacaacttg attggtcatc taggcattat tgaaaacgtt gaacttggga tgacattaag
    23101 tggtgtttct aaagacgaaa aacgaaaacg ggcagaagat gcattgcacc gagtcggctt
    23161 gacagatcat atgcataaaa agccaaatca gttatctggt ggacaaatgc agcgagtggc
    23221 catcgctcga gcactagcca atgacccaga tatccttttg tgcgatgaac caaccggagc
    23281 gttagataca gaaacaagta tccagatcat ggaattgatc caagagttat cgaaagaaaa
    23341 attagtgatc atggtcacac ataatcctga actggcccat caatacgcag atcggatcat
    23401 tgaattttct gatggtaaga tcttaacaga ttcccatcct cacatcgaac gaccaaaaga
    23461 tgatcaattt aacttacgca gaacaaagat gagtttttgg acagcgttaa agctttcctt
    23521 caacaatatc cgaacaaaaa aaggacgtac tttcttgacc tcctttgctt ccagtattgg
    23581 gatcatcgga atcgcgatcg ttctgtccct ttcttctgga ttccaaaaac aaatcgataa
    23641 cacgcaagct gaaacgatgg cgaaatttcc gattactatt tctaaggtaa cgactaacca
    23701 gactcgtgac gatgccggat tgggtgcaag caaagcggat tatccagaca gcaaaacgat
    23761 tactgcaaaa gtcagcgaag aagataaagc acagcacacg aataagattg atcaaacata
    23821 cgtcgattac gtaacagaca tcgatcctaa cttaagtaat aatatcggat ttacccgtac
    23881 tacaggaatc aatcttttac gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa
    23941 tcaaaatcct gatacggaat ctctttcttt atctagtacg atgtcagcaa tgacaggtgt
    24001 gggagtgtca agtttcccta cacagcttga cactagcaaa gaaaactttt taaaagacaa
    24061 ttattcttta cttgccggaa gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga
    24121 cggcaataat aatactaata tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga
    24181 cgaaaaactt gattttgatg atatcgttgg tacaacattc aaattagtaa acaacaatac
    24241 ttactataca aaacttccaa ctgggaattt tatccctaat acagattatg atgcgatgta
    24301 tcagaatgct tctgatgaat tgaagatctc ggggatccta cgcgtgaaat cttcttctac
    24361 aatgaatctc ttatctccag gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa
    24421 cgaaaacaaa gaatcagaaa tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac
    24481 tactgaaaaa gttgacgaaa atgccaaaca aacattgctt agttatttag gtggagacag
    24541 cttgccttca agtatcatga tttatccgaa caattttgaa gacaaagaaa agatcttgga
    24601 ttatctagat gattacaata aaggcaaatc agatgaagat aaaatcattt atactgattt
    24661 agctggaacg atgactgaac tgactggcgg attgatggat gctatcactt atgtccttat
    24721 tgcttttgca gggatctctt tagtaacaag tatgatcatg atcagtatca ttacttatac
    24781 atctgtgatt gaacggacaa aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa
    24841 agacatcact cgcgtatttg acgcagaaac gtgtatttta ggtatttctt ctgggatatt
    24901 aggtgtgttt attgcatggc tagctacgtt ccctatcaat agcatcttat acaacatgac
    24961 ggatctaaaa aatgttgctc aactaaatcc tgtccatgcg attattctag tgatcgtctc
    25021 tactatattg acgatgcttg gcggtcatct tcctgcacga atggcagcga aaaaagacgc
    25081 cgctatcgct ttgcgtgcag aataaggttg tgacaaccac atttagattt gagtcataag
    25141 agcgctgaaa tagtagaaaa cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc
    25201 tgtttttttt aattattttt tataattctg gtatactttt ctttcctttg taccacaact
    25261 cttctggcgt atacctgtct tttccattta tgaatactgt tccatctgct tcaatcgtta
    25321 cttcagtccc aatccacata ttacgagaaa gtgcgagaag attttttctt tttcctcttc
    25381 ctttttttcc aaattgcaag gcatcggtta tctcttctgt ccaatgagat ttcacgtatt
    25441 ttacttctcc gttttcaaat gtaactttca aaatattcgc tatattttcc acttttactg
    25501 ctttaggaaa tgactccttc atttttttca ctttccttcc tccaacacta agtatgcgct
    25561 ttcttttagt gataagtata tcatagttta ttctattatc aaaaaaacgc atccattcca
    25621 ttgtagaata ctttaccgaa caagttgaat tgttttcctc tttttcacct tttactatag
    25681 ataggtaaag acaactaagg aggaatctct catgacagat caaccgtatg atttaagaaa
    25741 agtcatcgaa gaactaaaaa cacttccagg tcaatatcac gaaacagata ttgaaatcga
    25801 tcctgaagca gaattatctg gtgtttaccg ttatatcggt gctggcggta cagtaaaacg
    25861 tccgactcaa gaaggaccag ctatgacttt caacaatatc aaaggtttcc ccggcacacg
    25921 tgtgaacatc ggaacaatgg ctagtcgtaa acgtgtaggt gaaattttgc accatgatta
    25981 tcgaacactt ggtcgtttct tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt
    26041 agacaaagca gacgctccag cacaagaagt cgttcatcta gctaccgatg cagacttcga
    26101 tattcgcaac attttgcctg cacctacaaa tactcctgaa gatgctggtc catacatcac
    26161 aatgggtgta gtcttaggat cagatccaga aaaaacaatg agcgatgtaa cgatccatcg
    26221 tatggttcta gaagataaag atacgatcgg tatgtacatc atgcctggcg gacgccacat
    26281 tggtcacttc caaaaacaat tcgaagcctt gaataaacca atgcctatca ctatcaatat
    26341 tggtttagat ccagcaattg ccattggcac gactttcgaa ccacctacca ctccacttgg
    26401 ctacaatgaa ctatggtgtg caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg
    26461 tatagcagtc gatgaagtgg gtattgctcg tgctgaattc atcattgaag cagaaatcat
    26521 gccaaatgaa acaatgcaag aagatatcaa cacgaactca ggaaaagcaa tgccagaatt
    26581 tcctggctat actggggatg ctaatccagc tgtacaagta gtgaaagtca aagcagttac
    26641 tcaccgaaaa gacaatccaa tcatgcaaac aacgattggt cccagtgaag aacacgtatc
    26701 tatggccggt attcctacag aagcaagtat tcttgccttg gtcgataaag ctattccagg
    26761 aaaagtagta aatgtctaca atcctcctgc aggtggtggt aaattgatga ccatcatgca
    26821 aatccgtaaa gaaaacgaag cggatgaagg tattcagcgt caagcagcta ttcttgcttt
    26881 atcagccttc aaagaattga agacagtcat tttagtcgat gaagatgttg atattttcga
    26941 catgaacgat gtagtttgga ctttcaacac tcgtttccaa ggagataaag atatcatcgt
    27001 gatcccagga atgaggaacc atccattgga cccatcagaa ttaccagaat ataatcctgg
    27061 ctctattcgt ttccgtggga tgagtgcaaa aactatcttt gacggtacag ttcctttcga
    27121 tatgaaagaa cattttgtac gtgcaaaatt ccaagaagta gaagattggg aaaaatattt
    27181 gaaataatga atgatctgca actgttttga catcataaaa aggagtgcgg aaaatggaac
    27241 aattggcaca acggaagaaa aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt
    27301 atgccatcaa cctagtgaag aaactaaaag aatatccgat gatagaaaca cacggaatca
    27361 tcagtccatg ggcaaaacag aacttaaagc tggaatccga cttatcacta actgaattcg
    27421 aaagcctgtt tgattaccat tattcaaaca aagatttagg tgctgctgtc gccagcggat
    27481 catttttgac cgatggaatg atcatcgtac cggcaagtat gaaaacagtc gcaggtatct
    27541 ctgttggttt aggcgacaac ctgattgcac gtgctgctga tgtaacaatg aaggagcaac
    27601 gaaagttagt cattgttcct cgtgaaacgc cattaaatgc cattcacttg gaaaacttga
    27661 ctaaattagc acgactaggt gtgcaaatca taccaccaat tcctgctttt tataatcagc
    27721 ctcaaacgat ccaagatctt gttaatcacc atacaatgaa acttttggat caatttggaa
    27781 ttgtaaatga gcattcaaaa cgttggcagg gtgattaata tggaaaaaga aacgatagtt
    27841 gaagtaacca aactaggttt cacgatccaa gctgctgtta aagtaatcgg taaagactta
    27901 ttgatcactt taacaggcgg agatacacca catatcggaa cagtcactac attttctcgt
    27961 gatacagaga tgcaaactgt acgtttccct agccacgatg gtcggttcca taaagacgat
    28021 gtcttagccg aaaaaatagc tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc
    28081 acttccggta tccatgttga ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg
    28141 tcagaagagt taggttacaa gattttagat tggttggaaa aaatagattt ccatatcaaa
    28201 gaaccagttt attataaaga tggtgaaaaa acattatgaa agaagaggtt gtgaaatcag
    28261 cgttatgacc tgagtatgag agaaaaaaat ggaaaaatag cttctcatat tttgccgttt
    28321 ttgagctaat accgagggac agctgattga acgccgttta tcaagaggtt gtgataaagc
    28381 cgcttcgttt cgagtagtaa gaaaaatttt gtaaacatgg gtttccacat ttttgcataa
    28441 atttgactta ctaccgagaa actggctttt gaacaccgtt tatcaagagg ttgtgacacg
    28501 tcttttgtca caacctcttt tatttttgct tcactgtaac tgctacaata tcaccgattt
    28561 cttttccgat gtttttacga atatcttttc gtagtccaag gatgtagcag actgaaccat
    28621 ctggattttt cacgcccata ttcacgatac tgccttcata cggcatattg tcaaaagttg
    28681 cttggacttt aactcttcca gcaccgaatt cttttcttat atcatacgga aaaataatat
    28741 atgccccgcc cttgtcgact tcggaagcat agatttttga ttcaaaagaa taaatttccc
    28801 tcattttatt tctcctattt tttacatcta gtatagcata gcaaaaaaaa gaaggaactg
    28861 tgacaaaagt cttgtcgcag ttcctttttt cgaataaacg gtgttctcct gccaactcct
    28921 cggtcacaag tcacaatagt caacaaacat gagaagctgt tttttgaaat tgctccttgt
    28981 gactcagagt taaacggcag gctcacaacc tcttccttaa acggtgttca aaagcttgca
    29041 tctacggcac taagcccaat cagatgaaaa atatggagtg ctatttttat ctgattgttc
    29101 ttactgcttg atgcagagca gctttttcac aacctcctac atggtgttca aaatattatt
    29161 cgccttttgc ttctttcact aattttgcga atgcttgttg ttggaattca gcagctaagg
    29221 ctttcgtacg ttgttcttgc tctgctttgc tcatttttgg attttcagtc attgctttta
    29281 ccataccgtc ttgaacataa gcttttgctt cactttccat cgtactttgc tgtttcttca
    29341 ctaattcagc taacttggct gcttggtccg tacttaattc tacccatgtc tctgggattt
    29401 tgaatgtatt cactcggctg tcatattcgt gattgttatc agcaatattg aaccagaatt
    29461 tatacatgtc gtttttgtat tcccaataag tagttttcgt cactttttca gcatcgccgt
    29521 ctgtcttttc tactttattt gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt
    29581 tttcatttgt tcggtaaaga tacacttttt cttttccatt ccctaaagct ttatacaaaa
    29641 gcatatctgc tccttgggaa tcagcactgg aaacaatttt ttctgttttt gtttccgtta
    29701 ctttttccat tccaaagtga ttggacaaat tagcgacgat caaacttagt gaagcgacga
    29761 agattagtcc gaaaatcaaa gataaaaagg tttgccatgt ttttttagcg aacacgttcg
    29821 ttaaagcaaa agcaagcaag ctgacaatca aaactccaat aatcatgcat tatcccccgc
    29881 tttcattaga acaggttctt ttttcttcaa taaaaaggca ataataaagc caagaatccc
    29941 aaagatgatc gctacgataa acgcggcatg gtaacctgac agtgtggcat tgattgcctg
    30001 atctttataa gctaatggcg tattatccaa tacagatttg cttgggatat ttgcttttgt
    30061 cacattcgtc aacacactga tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa
    30121 tgtattattt accgctgtcc catgactgat caagttattt ggcaatgcat tcataccaga
    30181 agtcgttacc ggcatcatga ccatggagat cccaaacata cggatcgcat aaaggatcac
    30241 gatatataaa actggagtcg tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa
    30301 aatgaacatc cctgtgatgg ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt
    30361 cacaggcatc atagccccca tgatcaatgc acccggcaac aacatcaagc cagaatggaa
    30421 tgctgattct ccacgaatat tttgaatata caatggtacg accatttctg cccctaccat
    30481 cgccatattt gttacaccag ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac
    30541 acgaagttcc aagaatggat gttccaaatg taattgacgc catgagaaca aggcgatgaa
    30601 aatcacacca acaactaaga aaccaattac tttcaagctt ccccagccgt catctcctac
    30661 actagaaaat ccgtaaagta aactaccgaa tccaatcgtt gataaaatag cggataaaat
    30721 atcaatgcta ggatttgaca atggaataac acttttcatt aggaagaatg ctaaaaccaa
    30781 gacaagaaca acgattggca gtaccatacc aaacaagtca cgccaatggt agttatcaat
    30841 gatataacca gataatgtag ggcctaaagc aggagcaagt ccaataacga tccctgacat
    30901 ccccattgct gatcctcttt tttctggcgg gaaaatagat agcatgatat tttgcaataa
    30961 tggcatcgat actcccacgc cgcaagcttg gatcaagcga ccgattagta atgtactaaa
    31021 attaggtgct gtaaagcaag taatcgttcc gatcaaaaag atcgtcatgg cagaaagata
    31081 taaatttctt gaactgaatt tattgatcag ccatgctgtt attgggatca tgatcccgtt
    31141 gactagcaag aaaccagtcg ttaaccattg cacatcagac gctgaaatat cgaaagcttt
    31201 catcaatgta ggaaaagctg tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc
    31261 aattaataag acaacaacta aaagtgtccg attatatggt tttccgtaaa tatctacggg
    31321 ttggttgtta ctcatatttc tccttctttc tgaatttttt ctgaaactac tagaatactt
    31381 tagtcctaaa ttcgctattt gtcaacctac ttgacacata agttaatacg gatataatta
    31441 agggaagcaa gaggacaaaa ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt
    31501 tggaaaatga tcaattggtt gttggcatca gtgaattaag tgatatcgta ggtgtgtctc
    31561 cacgtcaatt aaggtattgg gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga
    31621 attgtcctag aaaatatcgt ttacctacag tcataaaagt agaactgatc aaaaaatatt
    31681 tagatgacgg atttactttg tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa
    31741 tgcaccatgt ccgtaaagtt ttttcaaaag caatcaaaga tatcgaattg atcgacgaac
    31801 gctatacgat tttacaaatc ggtaacttca aagaagagaa tgctaagatg tacatcattc
    31861 atgacaacga gacagacgaa ttaacttaca agctccttcc tgtcgatgaa aaagctgact
    31921 acgaacagtt gttaaaagaa ctctaaacgc cactaatctc ctaagtacca agctttttaa
    31981 taagtagatg ctacataaat acttgaaaaa aggcctgttt gaacataaga atatccgaac
    32041 ggtgatctgc gtttctttca tatagaaagg aattctccat cactgttcgg atattttttt
    32101 atttttttcg gttactttct tctaatacat ctgttagcca atttgcatat tctgtttccc
    32161 gattgatcgc atgcgctaaa atcaggtagt gtccgtaatt ttcatgtttt tctttttcag
    32221 taggaaagat cgtttttttt cgctctaata gatgaagtcg tttttcttca tgaaggtcac
    32281 gctgctgctg aataatttct actaatgccg gatcattcac gtctttgacg aaatacaatt
    32341 tcagaacaaa ttcgtctcga ttaaccggta gttcattggt tggtgtatga atccactctg
    32401 ccaattgttc cttcccttct tctgttaatt cataaacttt cttttccaat ttttcacctg
    32461 tgatctctac ttgatgctga atgattcctt gctcttccat ttttgcaagt tcaggataaa
    32521 tctgactatg ttttgcttgc caaaattctc ctatttcatt tttgaacgat tgattcaatt
    32581 catatcctgt catcttcttc ttacttaata accctaacaa aatatatcga agtgtatttt
    32641 ttcttgccat cagttttccc tccttgacaa atctttaaat ccattctatc ataaatgagt
    32701 aatcgaaaac atgtagttta ttacatgttt taatttataa ggagatgctt aaacatgaaa
    32761 gaatttaaag aattggaaga ttttattgga actcacttta tctatacgta tgacaatggt
    32821 tgggaatatg aatggtatgc caaaaatgac catactgttg attaccgtat ccatggcgga
    32881 atggtcaaag gccgttgggt aaaagaccaa gaagctgata tcgttaaatt gacggacggc
    32941 gtattcaaaa tcacttggac agagccaaca gggacagacg tggcattgga ctttatgcca
    33001 aatgaaaaga aacttcacgg aatgatcttt ttccctaaat gggttgaaga acatccagaa
    33061 atcactgtta ctttccaaaa cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat
    33121 gaaacttatc caaaattact tgttcctgaa tttgctacga tcacttatat gggtgatgca
    33181 ggtatagaca atgaagatgt tattagcgaa gaaccatacg atggaatgcc agatgatatc
    33241 cgtagcggaa aatacttcga tgaaaattat aaacgagtaa aataaggttg tgaaagagag
    33301 gttgtgaaat cagcgttctg acctgagtat tagagaaaga aacggaaaaa tagttcctca
    33361 tgttttgccg ttttttgagc taataccgag ggtcagctga ttgaacaccg tttatcaaga
    33421 ggttgtgaaa tcagcgttat gctttgagta ataagaacgc tagttagaaa atagcttttc
    33481 atattttcta ggctagtggg cttattaccg agaagcagcc gtttgaacac cgtttatcaa
    33541 gaggttgtga aatcagcgtt ttgacctgag tattagagaa acaaatggaa aaatagttcc
    33601 tcatattttg ccgttttttg agctaatacc gagggtcagc tgattgaaca ccgtttatca
    33661 aagattgtaa caactgcata ttcacacagt taaattagtg acttcaaaat gaaataatgc
    33721 tcccagcaaa aaattaggct gggagcatta tttcgttatt ctgttcatca aaaatcagcg
    33781 ttttgattcc atttcatcac aagttcctcc tcatttactg cttcatcttt ttgctgtgtt
    33841 tgaattgtaa aaccttgtga aagatagaaa tgaatagctg attgattttt ttgatagact
    33901 gtcaaagtca gtgttttatt ggtttctttt atttttttca ttagttgcgt accgattctt
    33961 tgttgccggt attccctttt cacaaagatt cctgcgataa actgatcaat caccccagca
    34021 aaaccaataa tttcttgatc tatttctgct aagtaaatca ctgcatctgg taaagctttc
    34081 ctaacagatt ctacttgatt ctcccaataa gttgatggaa tgaattcatg agaatccaag
    34141 ttagcatgca gccaaatcga tagaacagat tccagttctt tggcagacaa ttttgttgtt
    34201 gtgcggatca ttttttctct ccttacttat tcattgattt taaaataaaa accatttttt
    34261 tgaagctctt ttacaagttt tcgcccctca aaaaagtata tcttctcttg ttttactttt
    34321 ctaataccaa aagaaacagc aactttagga tcatcagctg aaacgattcg ataagttcca
    34381 ccaggcaatt gatccagctt gactttccca tgatggtcgc tttgtactga aaacggcaca
    34441 ccatttctag taagtgtttt tttcttatgt ttcaaaatga atgaactacc atttaccggt
    34501 ttccctgacg aatcactaat aataaatgaa aaatcaagca cttttttact taatctatac
    34561 tgatagatta gtcgtccgat aaacactaac agtatgacta cagctattat cgttcctgca
    34621 agaataaacc attgccgcat ggttctttcc tgatttcctt ttccttcttc tttttttacc
    34681 gattcgttat aaggaatccg atgtcctgtc actagcaaac gatgcgtgtt gatcatatac
    34741 ggcgtacatg taagcaaggt aactaagtct tctccttctg aaatcgttag aacagacgtg
    34801 tcatctggca gtaccacttg tatattttta acttgataag ccaatttctc ccccaaaaca
    34861 gtcaaaataa acgtgtctcc gttttctaaa cgatctaatt cggtaaataa ccgtcgatta
    34921 ggtaaaccgc tgtgagcaga gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag
    34981 gttccttgca agacgcctgc tccattttca aggatcctac cattgagccg atcataaagt
    35041 gaaatattta attggatctt aggtatattg atacttccga tcagccattc ctctaattgg
    35101 ctggatgttg tactttcatt tctgttcttt tcattgaaag gatcagtacc aggattgaat
    35161 ccttggtcag ttaatcgttg ttttttctcc tccattttct ttcgctgcac ttcaatttca
    35221 gctgcggtcc gtttttgtac ttgttcgata cgtttttgat caataaaact atttaaagaa
    35281 tccacataaa atggatataa agcgatcagt aaccctacga cgatacatat taataaaaac
    35341 aaacgaaaca aaagtcgacg agactgtttt tgcttactct gcttcacatg tgtcctccct
    35401 tgcaagtttt tttgttcttt cttttattat atgggttcag gaaaaaaata gaaaatgaaa
    35461 gccgatgagg ttgtgaaaaa gctgtcctgc atcaagtaat aagtacagcc caaaaaaata
    35521 gctactcata ttttttgttg ggttgggctt attaccgcag atgcaagctt ttgaacaccg
    35581 tttaaggaag aggttgtgaa aactgcgtta tgctttgagt aataagagcg ctagtcagaa
    35641 aacagcttct catattttct aggctagtga gcttattacc gagaagcagc tgattgaaca
    35701 ccgtttaccg agaggtcatg aaaaagctac tttgtttcga gtattaagaa aaattctgtt
    35761 tcaaaacaag gagatgcaac aaaacttatg tcgcatcctc tctccttaga actttcactt
    35821 atgtttttct tgtaaaattc ataaatattt tcatgaattt tctaatttct tgcctacctc
    35881 tcgcatagga tatatgatga atttatctaa agtttgcaaa ggagttcgac aattgaaaaa
    35941 atatggccca tttttagcaa tttttttcat tgctttggca tttctcatgc ctcatttatt
    36001 cacacataaa ctaattttgg gtgctgatgc cccattccat tacaatcggt tctatgatgc
    36061 cgcgcaacaa attaaatatg gggatttcca ttattttcct tccctttatg gattccagca
    36121 aagtggcagg atcgtgaatg ccgtttacgg cccatttttc gcttatttac aaggattgat
    36181 cgtgttgctt gcaggtagct ggtttcatta tcagattctt tcaaatttca ttctttatct
    36241 tatttcagga ttttctatgc tgattttact gagatatgtc aatgttcgaa attgggtaag
    36301 tgtaccagta gccgttttat tcatgagtac gtattctatt caatactggt ctatcaacca
    36361 aggattcact agctggggga cttgttttta tcctttatgt atgatcccta ttgctgattt
    36421 cgtccttcat aaaaagttcc ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca
    36481 gatccattta ctgtcttcga tcatgttagc tttgatgtat atcccttttt atctttatta
    36541 cttttttaac cagactgaaa aaggaaaagc actgcttcaa ctgattaagt cggtcttgct
    36601 ttattttgtt ctgacagcaa atatttgggc aggattagct attgtttaca gtgggaataa
    36661 gattcttcct ccctttgtta acagagaaat gagtcaaaag gcgatagatc tggatggcag
    36721 ttattggctc cattacccta aggcctttcc tatattgata ttatcaggtt ttttgctttt
    36781 tattttcttt caacaaaaga acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt
    36841 tttctttttt ctttctacta gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc
    36901 ttttattagt ttgatccagt ttccatttcg atttttcgtg ccatttacgc tattgcttct
    36961 actttacctt gccctttcac tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag
    37021 tatatttggc attcttattt tttcagcaca gacgatccag aacttatacc agcatctgga
    37081 aaagtgggaa aatgaaacat ttgtcagtcg acatacttat ctattcgata cgccggaaga
    37141 agcaaggaaa acattcttca gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac
    37201 cacacctgac tatctgccaa tctataagga gacaaaagac aataaatacg accggtataa
    37261 cgaagaaata ctagaaaacg aaacaacttt tataaaaaca catccaggcg gtcttttgac
    37321 aatcaagtgg aaaaacactg gggacaaaac tgttcatatc cctgttatcg tctacgatcg
    37381 gactgtgcta cagcaaaatg gaaaaacatt gactgattat gaagtaacag atatcgggac
    37441 cccaatcgtg aagcagaaaa aaggaatcaa cgagctcacg cttcattatc aaacgccaat
    37501 ctatttctat ttcattcttt ctcttacttt gattggctgg tttaccttgc tatgtttatt
    37561 tatttatcat agatacaagc ttttacgtgc ttaggcaaaa gggataaata catccgatca
    37621 aaaaactctc caaacggtat aatcgtttgg agagttttat tttaatcagt ttttttatgt
    37681 tatatgttat attttttatt cgttcacatc taattcgatt tccaccccgt agtgatcact
    37741 gatgattgga ctatcgatcc catcaaaaat ccgttgatat tttttaacct gcattccttc
    37801 agggacgaaa ataaaatcta tacgcaattt ttctgtattt tgttcccaac catctatttt
    37861 cttttccaca gtagctgctt ttcctttttc attcgcgaca acatacgaat cttgaagaag
    37921 aaggcaactt tctcttacag tataataacc ttgagagtct actggattat tgaaatcacc
    37981 taggaaaaaa agtggtacgc gagtttccaa aaagtagttt tccaagtttt tccactcaaa
    38041 ataaaagcca ctttttttat ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc
    38101 ctgatcatct atctttgttt tcccaatcaa gatcttgcgt gtctgataat cttctttctt
    38161 ttgagattgg gagacggtaa ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt
    38221 tccttcttca tatttatcat aaccgatgtg gctcatttcc caactccaaa aatactcttt
    38281 tccgtgttcc tttaaaagct gaactaaacg gtaggcaaaa ttatctttac ggataggtac
    38341 ttgattcttt acctgacaga acttcattag cttcgcaggt tctacttctt cagattccag
    38401 taattggttg atttcttgta aagcaatcac ttcataatct tctaacagga tcttatctgc
    38461 taattcttgc aattttttct ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat
    38521 gaatttcatt ggttttctcc ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt
    38581 tgtcacaacc tctccagcaa atagtgttct cctgctaact cctcagtaat aagctcaatg
    38641 gaccaggagc tattttttgt ttggctgttt ttatcacttg gtgcagggca gctttttcac
    38701 gacctctcca ctaaacagta ttcaaactgc tgcttctcgg taataagccc aaccaaacga
    38761 aaaataggag gagctatttt tgtttggctg ttcttatgac ttgatgcagg acagcttttt
    38821 cacaacctct ccttacattt taatggagcc gatcacttta ccagctgtca ctgtacctaa
    38881 ttgcttgatc actacttctt ctactttatc gtttgtaaat acgatcatga tcgttggatc
    38941 tttttcttcg ttttggatca catcaagatc catctcagct aatttcgttc ctgttcctac
    39001 ttcttggcct tctttgacag caatctcaaa agctggctga ttcatttgga ctgtatcgat
    39061 tcccatatgg atcaaaactt cgataccatc tttcgtttcc agcccaattg catgtttgct
    39121 agggaaaata cttgtcactt ttccagcgat cggcgcaaca acttctcttg atgttggaat
    39181 aacagcaaag ccgtcaccca tcattttttg tgagaatacc ggatctttta cttcagataa
    39241 aggaatcact tctccagaag ctgcggaaac tagttcttgt tctataccta agtattgctt
    39301 actacctgct tgtccatttc ctgtagaaac catttctggc tctggaatct ctgctcctga
    39361 ttgcagcaga tcttcgatat ctgatttcaa gacatctgct tttggtccat aaactgcttg
    39421 gactccattg tctttgacga tcaatcccat cgcccctgct cgtttccagg cttcttcagt
    39481 ccctactttt tctcgatcat ttacacttac gcgtaaccga gtcatacaag catcgacatc
    39541 tttgatattt tcttttcctc ccagcaaatg aatgatctgg accacttgct gatctgctgt
    39601 tcctgttccg ctgttagata caacggtttc ttcactgtca ttgtcgtaat ttccgttacg
    39661 tcccggtgta gcaaagttga attttttgat caagaaattt gctaagaaat acgtaacaac
    39721 accaaaagcg atcacacaca acacgaagtt gataagatct ccacctagac ccgctttgat
    39781 agctaacggt gtccgagtca gcaattcgat attcccaaat gaatggaccc gcaatggcaa
    39841 gatatctgcc atcgcaaatg cagccccttg gatcactgaa taaatgacat ataatggcac
    39901 agcagcaaac ataaacatga actccaatgg ttctgttaca cctgttagaa agacagccaa
    39961 cgctgctgaa aaatacattg atttatatct tgctttctta tcaggatcga cattacgata
    40021 catcgcaaaa gccattccca tcaagatacc tgaagaacca atcatttgtc ctactttgaa
    40081 acgagccggc gtccagttat gcaacacaaa ctcatattgc gacatatccc ctgcaccttt
    40141 aagattcact aaatcagtgg cccaagccaa ccataacgga tcttgcccaa atacttgtgt
    40201 ccccgcctgt gcgcctgata aaatctcata cgatccgcca agctgtgtat agttgatagg
    40261 aatcgtcagc atatgatgca atccaaatgg caatagtaaa cgttctaatg ttccaaataa
    40321 aaacggtgct agaatcggtg cgctttcttg tgattctgca atccataaac caaaattatt
    40381 gattccagcc tgtacgtttg gccacaccac agcaagaatc aatgccacga ttgttgacca
    40441 taagataaca acaaacggaa caaagcgctt tccattgaaa aatgacaaag catccggcaa
    40501 ttttctataa ttatagtact tattataagc cattgccccg acaaatccag cgatgatccc
    40561 tacgaatact cccatattca aagctggtgc ttccaataca cttgtaaaaa atcctttaac
    40621 catgatcttc gtaccgaaca gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact
    40681 tgtgacacca aagatagccc cagtgatccg attgattaaa ataaatgaga tcccagctgc
    40741 aaatgctccg cctgctcttt cttttgccca acttcctcct attgctaaag caaataaaat
    40801 atgaagatta ccaataattg cccaaccaat attttcaatt actccgcccg ttgtgacaag
    40861 cggcgtccaa tcaggattga tcaagggaat tgatttccct atactgatca tcaacccagc
    40921 tgccggcata actgctacca caaccattaa agcctttcca aatttttgcc aaaactcaaa
    40981 actaaatatc tttttcattc cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt
    41041 atagcgtgcg ttttcttttt tgtaaatgct ttatttttta tttttctgtc tataccattc
    41101 tataaaacct ataatacgtg tgttcccttc tataattttc tcctaaaaat ttattttttt
    41161 aagctttttt ctatgaaata ttttcttttg tctattgact tgtgcaatcg gttgcgttta
    41221 ttatgaacgt ataaaacagc tcattaggag gagaaaaatg aaacagatca aacgactatt
    41281 tgctattgat ccatggaaaa tcagcacgac acaattagat aaaaaaaatc ttcgactgca
    41341 agaatcttta acaagtattg gaaacggtta tatggggatg cgcgggaact ttgaagaaac
    41401 ttactcaggg gaccaccatc aaggtactta tttggcgggt gtctggtatc ccgataagac
    41461 acgtgtcggc tggtggaaaa atggttatcc agaatacttt ggaaaagtga tcaacgcctt
    41521 gaactttatc gcgatagata tttcgatcaa cgatcagctg atcgacttgg cttctttgga
    41581 accagaagac ttttactggg aattagatat gaaaaatggt gtattatctc gtacattcac
    41641 aatcactact tctactaata aagtacgcat ttccttcgaa cgttttctga gcattgtcaa
    41701 aaaagaatca gcttatatct atttaactat agaaatgctt gaaggtagcg gaacagtcaa
    41761 actcgtatca aaattggatg gaaatgttca aaacgaagac agcaactatg atgaacattt
    41821 ttggaatgag attgatcgtg gaactataga agaaatcggc tatttgacga ctaaaactat
    41881 tccaaacaac tttgggattg aacaatttac tgttactgca gcaatgcgcc atttcgttaa
    41941 tggaaaatca gtcatccctg actatcacga agatacttta gcattacatg gttgcttgtc
    42001 tgcagaatta tctcaaggtg agacatggtc agtggaaaaa gaaattatcg ttcttactag
    42061 tagagatatt ccagaagcgc agcaagcaga aaaagctgtc tcagaattaa cgaaccagac
    42121 aaacaattat atccaagcaa aagaagagca aacagcggct tgggcagaac gatggaagct
    42181 tgccgatgtg gtcatcgaag gagacgaaga agcacaacaa ggtattcgat tcaatttgtt
    42241 ccaactattc tctacttact acggcgaaga tgaacgattg aatatcggcc ccaaaggatt
    42301 cacaggagaa aaatacggcg gagccactta ctgggataca gaagcgtatg ctgtccctct
    42361 ttatcttgct ttagccaaac ctgaagtaac taagaatctg ctgaaatatc ggcataatca
    42421 actgccgcaa gcaatccaca acgctcagca acaaggatta aaaggcgcgc tttatcctat
    42481 ggtcaccttc actggtgtcg aatgccataa cgagtgggaa atcacattcg aggagattca
    42541 ccgaaatggc gcgattgcct atgcaatcta caattatacg aattacaccg gcgatacgga
    42601 atatttgaaa aatgaaggac tggaagtttt agcagaaatc gcacgcttct gggcagaccg
    42661 tgtccatttt tcaaaacgag caaataaata catgatccac ggtgtgaccg gcccaaacga
    42721 atatgagaac aatatcaata acaattggta tacaaatacg atcgcagctt gggtcttgcg
    42781 ttacacgcga gaaaattatt taacttatca aaaagaagct gctatcacta tcagcgaaga
    42841 agaactagcc aaatggaaag atatcgcaga gaacatgtac ttcccagttg acgaagaatt
    42901 aggaatcttt gtccagcatg acacattctt agataaagat ctcatgcctg tatccgatat
    42961 tcccacaagc gatcttcctc tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg
    43021 cttcatcaag caggcagatg tactacaggg gatttatttc ttcaatgata cttttacaaa
    43081 agaagaaaag caaaaaaact ttgatttcta tgaaccaatg actgtccatg agtcttccct
    43141 ttcgccaagt atccattcga ttttagcagc agaattagga atggaaagca aagctgtaga
    43201 aatgtaccag cgaacagctc gcttggattt ggataattac aataacgaca cagaagacgg
    43261 cttgcacatc acttccatga ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat
    43321 gaaaactgcc catgatcagt tgagattcgc accatttctg ccaaaaactt ggaaagctta
    43381 ttctttccat atcaattatc gcggacgttt attgttcatc tcagtcacag atgaacaagt
    43441 tactttcgag ttattagaag gttttcctct agaaatttac gtctatgaac agtcttattc
    43501 tttagcggat cgtctagaaa taacgctaag aaaggaggaa gcaaatgttt aaaggggtat
    43561 tgtttgattt agacggtgtc attaccgata ctgctgaatt ccattatcgt gcttggcgaa
    43621 agcttggtca ggaaatcggc attacgatcg accacacatt caacgaacag ctaaaaggcg
    43681 tcagccgaga agactcactc tctttgcttt tagcttatgg cggaaaagaa cactcttttt
    43741 caaaggaaga atttgcagaa ttagcgaaaa gaaaaaacga ttattattta gagatgatcc
    43801 agacgatcga accaaaagat gtcttccccg gggtcgtgcc tttactggat tctttaaaag
    43861 aagaaaaaat caagattgct cttgcttctg caagtaaaaa cgggccattc ctacttgaaa
    43921 aaatgggtct tacaccttac tttgatgcta ttgccgaccc ggcagaagca acaaacggaa
    43981 aacctgcgcc agatatcttc ctccttgcag caaaagctgt cggactaaaa gcagaagaat
    44041 gtatcgggat cgaagacgcg caagccggta tccaagccat cctctcaagt ggcgctcaac
    44101 caattggcgt gggacgtgct gaagaccttg gagaggagat cccgcttgtc cctgatacga
    44161 cttttcttac gatcgattac ttgaaagaaa agtgtcatga ccatggataa tccagagatc
    44221 tccgtcgtac cagttccaga gactgaaata aagaaaatca cattgaagaa cgactactta
    44281 gaagtcgttc ttctcaatta cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa
    44341 ggaaaatcag aaaatgtttt attgtcttac gatcgtttcg aagatgttct aacagacaaa
    44401 agcttttttg gagcaactgt cggacctgta gccggaagga tccgggatgc ttcttggggt
    44461 gagcatagat tggagaaaaa ctgcggatca caccatatcc acggtggcac gaaaggctgg
    44521 tctttccaat tttgggaagt agaagttttc aaaactccat catcaatagg tgtggtcttt
    44581 tacttaaaag atgaattttc tacctatcca ggaccaatca ctgctacgat cacttaccgt
    44641 ttaacaaaaa acgaattaga gatgacaacc tctgctagta gccttgttga aaccatctgc
    44701 aatccgacca accatgccta cttcaacctt tcaggaaatg gaacaagaga catctatgaa
    44761 catcagttaa cggtcttttt agatggtgtg cttgaattag atcaagaaaa actgcctact
    44821 ggaaattgga caaaaaaaga aaaactgcca atcgacttta gaaaatcccc aacactgcaa
    44881 gagatccttg catgttatcc agatggacta gatgatgtat ttcttttgca tcatcctagg
    44941 ctttccaaaa cttccttaca attattcgag aagcattctg gtcgccaaat gactatagca
    45001 acttctaata aaagtatggt attattttct acgactggat tcgaagctga tttctctgtc
    45061 aatggaaaac agatgcattc aaactacgga ttagcaatcg aaccgcaaga aatccctgat
    45121 atcgttcatt tccccaaatt tggatcgatc aacctccatc ctggtcaaga acggatcagt
    45181 cagacgattt atcggttctc tgcacaataa caagagaaag gtgtttttat catggctatt
    45241 accgtaaaag atgtggcgaa aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc
    45301 aacgatcatc ctagtatttc cgagacaaca aagaagaaag tccgaaaaat tatggatgaa
    45361 ctaggttatg ttcctaacat gactgcccgc aatctaggaa aacgcatttc cagtgccatc
    45421 ggcgtaatct taccccctct tgattcaaaa gagcggatcg gtaacccatt ttatcttgag
    45481 atcatggaag caatcaacga agaagcgcgg aattatgata tgactacagc aatcgctact
    45541 gctaaaaatt ttgaattgct gttagagaac gtccagcgta tgcatttaca aaaacaagta
    45601 gatggtttta ttctagtgta ttcagatagt caagatcctg tcattgatta tttataccaa
    45661 aaccacatcc ctttcacttt gatcggacag ccttatcatc atgagaacga aatcgtttat
    45721 gtagataatg ataaccagct tctaggtaaa caagcaacag aatttttgat ccagaatgga
    45781 cataagaata tcctgtttgt gacaaacacg actcatgaaa gtttgtattt cgaacgatat
    45841 ttcggttatc aaaaagcaat gatgatggct ggtcttcctg cgttatccag tgtagtacta
    45901 gagcatccgg aggattatct gtcctttgag aaaacgttga aagaaaacga agccacagca
    45961 ttggtggtca ttgacgatat cttcgccctt cgcacgatgc agttggcgca aatgtacggc
    46021 tatgtcattc cagagacact ctccgtcatt agcttcaaca actcgatctt ctcaacatta
    46081 acacaccctt accttacaag tatcgatatc gatatctccg aattaggacg tgtcgctatg
    46141 caaaagctgc gcgaattgat ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct
    46201 catcgcttga tcaaaagaga gacagtcgtt cctttagaaa acccatacta aatagctgac
    46261 tcactaaata cgctgaccat ttatcctatg gtcagctttt tatgtaaaag aagatactac
    46321 ttctaacaca ttgtttatct gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt
    46381 ctcacgctct aaacacgtat aaacggcgga agcagaagca actccttcgg aaataagctg
    46441 aaattcacaa aaatttaaaa agcaattttc ttgagtttct tcttatttct tggagttaaa
    46501 cgcttctgtc ccagcctctt ttttccttcc ttcaattttt tacacgtcga cgattcaata
    46561 aaaaaccgcc taatattgta aagacaggtg caagaatcga gaaaaagacg aatggcaagt
    46621 aatgcaacgc gctaactttc atcgttccca taatgaatgt gccgctgact ccccacggta
    46681 cgagagaatt gacggtcgca cctgaatccg ctagtgttcg tgtcaaatag gtttttgata
    46741 agccaacgtc atcaaaagaa cgcttgaatg tttctcctgg aagaatgatg gacagatact
    46801 gttctccaac gatcagattg attccgatac agctcaaggc agtaaacccg actaaacgag
    46861 aaggtcggtc catcttttct tttaattctt gaacgatggt atcaacgatc agatatttga
    46921 tcagtaaccc acctaatgcc aatgcaagta aaatcaaact agcagaacct aacatactca
    46981 tgatcccgcc tcgagaaagc agttcatcta gctttggatc aggtgtattt gcgacataac
    47041 cattcatcaa gatgtctgct gcttttccga ccgtcaaact tttctcatgg ataaaagaaa
    47101 gaacgagagc agctgtcgat cccgctagta atgtagggat agccggaatt tttttgattg
    47161 cccccccaaa taaaataact agtggaatca atgtccaagg agagatccaa aagctcgctt
    47221 tcatgttttg gatcatttca ttgatactag ctagatcggc tgaatgactg ttatgtccta
    47281 atatcgtata aaaaatcaac gaaaggacga atgctgggaa atccgtataa cgcataccag
    47341 cgatatgttc gaatagatta actcctccaa tacccgctgc caagttggtc gtatctgata
    47401 aaggcgagca gttattccct aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat
    47461 cattgaatcc aagtaaatga ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg
    47521 taaatgaact gccgacagtc actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa
    47581 agaaacgcac agaaacaagt ttaaatccat aaaccataat cgtagggatg gttccagata
    47641 aaatccatga agcaactaag acaccaatca aaagaaaaat caggattgga atgatccctg
    47701 gagtgattcc tttgatgatc ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc
    47761 cataaaacaa caaacacatg aaagctgcaa ggatcgggat atgtggcgag agctggaatc
    47821 cgatgatcag tactcctagg agtgccaaca acacgatcaa tacagcgata ctttctttta
    47881 aagaaatatt tttattcatc gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa
    47941 aaactattca cttggcagga cctcctacta aatcagcgac aaaacgtcgg ctgaaagact
    48001 tatttttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
    48061 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
    48121 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
    48181 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
    48241 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
    48301 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
    48361 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
    48421 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
    48481 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
    48541 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
    48601 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
    48661 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
    48721 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
    48781 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
    48841 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
    48901 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
    48961 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
    49021 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
    49081 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
    49141 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
    49201 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
    49261 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
    49321 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
    49381 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
    49441 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
    49501 caattcagcg aatatttgag gggattcttt gagtctattg cttgaagggt ttcttcaaag
    49561 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
    49621 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
    49681 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
    49741 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
    49801 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
    49861 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
    49921 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
    49981 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
    50041 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
    50101 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
    50161 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
    50221 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
    50281 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
    50341 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
    50401 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
    50461 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
    50521 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
    50581 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
    50641 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
    50701 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
    50761 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
    50821 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
    50881 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
    50941 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
    51001 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
    51061 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
    51121 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
    51181 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
    51241 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
    51301 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
    51361 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
    51421 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
    51481 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
    51541 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
    51601 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
    51661 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
    51721 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
    51781 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
    51841 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
    51901 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
    51961 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
    52021 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
    52081 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
    52141 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
    52201 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
    52261 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
    52321 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
    52381 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
    52441 tgggatcgtt aaaccgaacg cttctacttc tggtccttct aattttcgga ttaggtctaa
    52501 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
    52561 tttatgcaga tgcaaaaagt cgatagattg cagaatttgg taagtaaact ctgtaaatga
    52621 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
    52681 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
    52741 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
    52801 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
    52861 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
    52921 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
    52981 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
    53041 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
    53101 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
    53161 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
    53221 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
    53281 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
    53341 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
    53401 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
    53461 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
    53521 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
    53581 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
    53641 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
    53701 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
    53761 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
    53821 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
    53881 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
    53941 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
    54001 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
    54061 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
    54121 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt taaatgattt gatccaaaaa
    54181 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
    54241 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
    54301 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
    54361 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
    54421 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
    54481 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
    54541 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
    54601 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
    54661 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
    54721 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
    54781 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
    54841 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
    54901 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
    54961 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
    55021 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
    55081 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
    55141 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
    55201 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
    55261 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
    55321 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
    55381 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
    55441 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
    55501 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
    55561 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
    55621 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
    55681 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
    55741 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
    55801 aaaataataa aaaaagtttt ataaaaaggt ataaaacctt tttattaaac tatttaatct
    55861 tgtttagtat atatttttag aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc
    55921 acacatttga aaaagagctt tggtcgtttc gaagctttaa aagatgtctc tttcaccgta
    55981 cattcaggtg aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc cacgacgatt
    56041 cggacacttt tagggattat aaaaaaagac ggcggaacgg caacgatttt tgggcaagat
    56101 gtatgggaag atagtttatc tatccatgaa cgtctttctt atgttccagg cgatatctct
    56161 ttgtggggaa atttgactgg aggagcgatc atcgatctct tcatgaagct tcatggaaaa
    56221 gggagtgctc aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc taagaaaaaa
    56281 gcaaaaaact attcaaaagg aaatcgccaa aaagtgggct tgattgctgc tttggctgtt
    56341 gattcggatc tctatttatt tgatgagcct acttctggtt tagatccttt gatggaaacg
    56401 attttccaag aagaagttga aaaattgaaa gaacagggca aatccatcct actttcttct
    56461 catattctca gtgaagtcga gcgactagcg gataaagtcg tgatcatacg cgaaggaaca
    56521 gtcgtagaag aaggaacact cgatgaattg cgtcatttga ctcgttcgac catcactata
    56581 gaaacagaag cagagaatag tcacttagca caattgaacg gtgtccatga ctttgtgcaa
    56641 aaaggtcacc tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat tttagctgaa
    56701 gcgtccaaat taggtgtgaa aaaatttgaa tctattccac cgactcttga ggatttattc
    56761 atgagacatt atgaaggatg aggaggaagc gaaatgactg ataaattttc acgctggtcc
    56821 accctttttt ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg gctagtcggt
    56881 gtcactgctt tttctggtgg ttttgtccct gcgtttgaag aattgacttc cggacaagga
    56941 ttagctggat tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt cggaccaact
    57001 ccagcttcga atgctgctga gtatacttta ggagcgatgt atgcaaatga aatgttgctt
    57061 ttttgcagtt tgtttgctgc tgtgatctct gttttacacg tggtgagcca aacgagaaaa
    57121 aaagaagaac ttggtctgat tgaacttatt cgttcctttc gagtcggacg tcaagcaaac
    57181 tctttagctg tcatcgctga aagtattctg atcaatttgc ttttagcaat atcgatcagc
    57241 tgtacgatga tttttttcca agcagattcg atcactgcag aaggtgcttg gctttttggg
    57301 ctatctgtag gtagtatggg gattttgggg agtgccgttg cactgtttgc tgcacaactg
    57361 atgccaagtt cagccagttc gaatggtctg tctttagcgt ttttaggtgg actttacctt
    57421 ctacgagcaa taacagatgt agctgattcc tccctttcga tgtggaatcc tttaggctgg
    57481 tcttatttga cctatccatt tacaactaac aactggattc ctttgcttta tttgtttttg
    57541 ttcagtctaa tcttgataat cagttcattt gttttagagg aacatcgaga tttgaacacc
    57601 ggctatatcc ccgaacgtga aggaaaaccg tatgctaaac gttctctttt atccttgcgt
    57661 ggtttattat tctatctaaa taaagggatg acaatcagtt ggcttatcac ttttggtttg
    57721 atgggggcgg catacggctc tatctacggg aatatgcaac agtttttaga aagtaacgac
    57781 ttaatgaaac agatgtttat ccaatctggc gtctcaattg aaaaaaactt tacaagcacg
    57841 atcatggtcg tcttgatttg tctagctgct attttaccaa ttgctagcat caatcgttta
    57901 tttacagaag aaacccacgg acgtatgaat cagctgttcg caacaaaaat ttctaggaac
    57961 caactttatt ggaccaatat gttactagct attctatttg ctatattggc aatcctgatt
    58021 agttctggtg cactagggct ttctgctttg gcttcgatga aggatgcgaa agacatggat
    58081 ctattgatgt ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt gtttatcgga
    58141 attagtggct ttctattcgg atggcttcct cgaatgggta aacttgctta tatctactta
    58201 gcttactcct ttgcactcaa ttactttggc ggaattttgg atttaccaga atggttttcc
    58261 aaaacagctg tccctagctg ggttccacgg atgccaaacg attcttttga tctttccgtg
    58321 ttccttacgt tatcatgtat cagccttgca ctgttcgtcc ttggttctat tggttatagg
    58381 cgaagagact tactagaagg ataataaaaa agcatgtaca atttcatgct agcctccaaa
    58441 tctgggtcaa aaatccaaca tttggaggtc atttttttat ttacaagtct tctaactgct
    58501 ctttatcaat gatccagact tctcgattct ttctttttac ataaccattc tcctctaata
    58561 atttaaattt tctagataaa gtttcggggg tcgtaccgat aaatgcagca agttctttca
    58621 ttttcattgg caggaaaaag tgatccttcc ctgtcgcttt agctaagtca agcagataga
    58681 cagcgactcg ttcttctact ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg
    58741 ttaatttctc aacgttgatt gctaaaagtt tcagactaag ggcgggataa tgcagtaaga
    58801 gttccgagaa atctttttgt ctcaatatgc aaatttccgt tttttctagt gcttcgccaa
    58861 ataaagactc atttggaacg cctagcaact ggctctctcc ctcatatccg cccggctcta
    58921 ttactcgtaa aagctgttcc tttccgctag cagataattg atacactttc atactgccgg
    58981 aggccacgat cactaattga ggttctccat tcggcgcaag aatctgttct cctttttcca
    59041 catagtgatg tttgacaagt gcgtgtactt tttcttgatc ttgctgtact aagtgattga
    59101 acaaaggaac aaatgaaaca cataaatgat catgactcat aatctctcct ccttctaaac
    59161 agctatttct aataaagaaa cataacttcc cttattccaa ctgataattt tcttttatca
    59221 tagcataaac gtcaagcgaa ccagatacca gcaaatagag tggatttctt tttgtccctt
    59281 gctttatttt ccttcttttg agaccttaag taattgattc ctatcaattt tttaaatatt
    59341 tactttttga ataatcaaaa acaaaccttc actcgcaagc cgagagtaag gtttgttttt
    59401 cgcattgctt atttcgtgtt gtctattgaa atttttccgc acctagcttt tgatatagtg
    59461 gtgctagttc ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt tcttgcggat
    59521 agaagaatag tttacccatt tgaaaggttc ggtctctcat cgcttttttc aactcttctt
    59581 gtttctttgt atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg
    59641 gttgcggcca tatgtaataa tccttgatat cgactgtttt gctccactct ttcagtatcg
    59701 caagcaactg gttatacgct gcaatgctac catatcgttc ttcgctttta taatgttggt
    59761 acatcaaata gatttggtat tgtttttgat tcaacaaaac tgctagacag gcattctcgt
    59821 cttgacgaga ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc cagccattcg
    59881 tccagctttc gattttaggt ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct
    59941 ggagctgaat ctctttccat ttttgccagt gttctttata ttctttcttg atttgttcaa
    60001 tcttatctgt tggatggctc tctttgagct gtttgaatgc gtagattggt cgatcaaaca
    60061 actgataatc tgattttcca agttccattg tttcgcctct ttccgttatc ttttgtattc
    60121 tacctgaatt ttgcgatatg gacaaataga ggttgtgaaa aagctgttct gcatcaagtc
    60181 ataagaacag ccaaacaaaa aactgcgatg agcatcaccg cagttttatt gaacttaagg
    60241 ttgattgatc acatctaaaa gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc
    60301 gatatgtccg attgcacgct ctcctagata ggaagctcgt ccttttttag ctaccaagac
    60361 tttggtgtgt tcttttgcct ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc
    60421 ctctgtgact ggcagccaaa catctaacat cgttttatcg tcagcttctg cctttcctcg
    60481 gctttgaata cccgctgttc cctgctcgat cacttcgcct aatttttctt gagaatcaat
    60541 agaatcgacc tcttttgtcg ctttcatcat gttcatgaat gcagatccgt ataacggacc
    60601 agaagcccca ccgactttcg atatcatcgc catagagaat actttgaatg tatcgctgat
    60661 tgtttcagga tgatcggctt gaaaagcttc ttcataagct gaaacccctc ttcccatgtt
    60721 atttccatgg tctccatcgc caatcggggt atctagatca ctgagatatt gtttgttctg
    60781 attgattgcc tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat
    60841 attatcaccc ttttatcttg agatttttta ccatgaaatc gtctgtacat tgctttctaa
    60901 agaatctttc cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc
    60961 tagtgaggtc ataaaattac cgacttttcg gaaaactaca ttgacgcctc tttcttccaa
    61021 cagagctaaa acatcattca tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc
    61081 gttgactagt acacctgctt cttttggtaa attcgagtaa tcatctaaaa tcttagtaac
    61141 aagttccttt gccagtactt tagaaggctg catcttttct cgacgatagc ctggctcacc
    61201 gtggatacca acaccatact cgatctcatc ttctcctagt tcgaatcctg gtttccctac
    61261 ttctggtaca gttgctgctc gaagcgctag accgatcgtc ttagttgcct gtacgacctt
    61321 ttctcccagt tctttcaact cagctaggga agcaccgttt cttgctgcat cgcccacgat
    61381 tttgtgtaca aggacagtac ctgcaactcc gcgttttcca gcagtatacg tactattttc
    61441 aacggcgata tcatcatcta cgatcacact ttctacttca atatcgtcca tagcagctaa
    61501 ttcctttgcc atatcgaagt tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac
    61561 tccttttcca ctatccgctt ccttaatagc cgtctgaatc tgatctggag ttggagaagt
    61621 aaacacatca ccaagcaccg ctgcacttaa catcccttcc cctacaaacc cggcatggga
    61681 tggttcatgt ccgcttcctc caccagaaac caaaccaact tgttccgctt tctgattctt
    61741 ggctacaaca cgggaagatt ctacacgatg aacaagttct ggatagcttt ttactaatcc
    61801 ttccagcatt tcttcgacaa tattgcttgg atcattcatg atttttttca atttattccc
    61861 atcctttctt tccggcattt tgtgcttctg ttaagatttg ctgagtatca tctgttatac
    61921 cggcagtgat ggctgctgca aaagctcctt ccactaaagg cgcatccacc agatgataac
    61981 gttgctgctg ctcttcttcc aacatgtctt ttgccagttc cgagttcaat accgcgctac
    62041 cgatatccgc aaaaacaaaa taactagctg catcgcttga ttcattgact gcttctacga
    62101 ttttcatcgg gtctgatccg atctcgccat ttattccgcc gagagaaaaa atttgcacct
    62161 cttcggattt ttgcatctgc tcaatcattt ctttaatacc atctgttact ttttgactat
    62221 gagaaataag caaaatactt tttttcacaa gaatcttcct ttcttttaca tagttgctaa
    62281 cgattggttt cgctttcatt aatgaacaat tcaagtatat aataaatttc taattttggg
    62341 aagatatgtg tagtgcttct tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg
    62401 aatgattaca acaacaacga acagtgtaga gggaaaagcc gtagtagctt ataaagggat
    62461 cgtttttggt gaggtcatta ctgggatcca tgcatttaaa gacttggagg cggggttgcg
    62521 aaatatcttt ggcggccgct caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga
    62581 agcacttgcc gaaatggccg aacgtgcaaa agcattagga gctgatgcga tcattggcgt
    62641 aaaaatggac tatgaagtat taggcagcga caatggcatg ctgatggtca catgtagtgg
    62701 aacagctgtc tccacgagat aagtagggga catctgtttt aataactaaa gagagatggg
    62761 acatgtagtg gcactcaaga attagatttt tcagtctaac ttcgaggtac tctaccttcc
    62821 catcctctct tttttatttc tttttgcgga tgattccgta agctgctgcg actaacacac
    62881 ccgcccctgc taaggaataa ctgacagaag ctgttttttc atttgttttt ggcaaagtct
    62941 gacttgttga tttggatggc tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg
    63001 tcactgattt ttctcctgcc gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta
    63061 agtcagcttt ttttgcttca aaatcattag caactgtttg tgcttcgctg atctttccgt
    63121 ggattgcttg actggccgct gtgatatccg cttgagtttg acttagcttt ccagaagctg
    63181 tttgagcaac ctgatttaat tgctgattga attcttttgc ttgttggatc ttcccgtcaa
    63241 gatctgtttg gacagcttcc gcttttgctt tcgcttcggc aagctttttc tcaagttgtg
    63301 cacggtcatt tcccacttta tttttaagat cagctaaatc ttgatcgatt gctgcttggt
    63361 cttctttcaa tttgtttttt gcagcttcta atgcttcttc gagttctttt cttttatttt
    63421 ccaagtcttg caaatgatcg atttggtcag aagaggtaga actatttatt gatgtatctt
    63481 ctgaagatga aatcgtttct cctgaattat ctgtcggtac attggaagtc atttctgttt
    63541 ccgaggcacc gttttcagca ccagaagagc ttatagttgt tgaaggttct gtttgagcag
    63601 gttcagaagt ttccgcaaaa gctgtctgtc ccaataagaa aatactggaa acagcaattg
    63661 gccagattaa cggcttcatt ctttttttca tcacttttcc catccttact actttttaac
    63721 taatttctta ttataagcaa aaatgtttgg aagaaccata aacacaacag gctgtttgtc
    63781 taaaaaacgg tgcatctttt atttttttgt acgttccggg cttttccatg tcccgcttcc
    63841 ataacctaaa atcgttttga ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac
    63901 tatccagaac aaaagcatat atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg
    63961 atcatctaca atcagcgaag ctagcaactg gaaaaatcct gcgaccattt caaagcagat
    64021 gaacacaaaa ctgaatgtaa aagtaatata aatctgttcg tagtttcctt gatatacata
    64081 atgcccgatt aatccagcaa aaagaactac ggaaatacaa aagaatattg accagacaat
    64141 actcaatgtt tgatcaatga agatgatcgt tcttccaata tgtttaaaag gatggagcat
    64201 cacttttttg aaattcgtca gccagacttc tgttccacct tttgcccaac gttttctttg
    64261 tcgatatagc atcttcaacg tcacaggtac ttccatgaaa aagataatct caggagcaaa
    64321 aacagataac cagtcattta actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg
    64381 atcttgtctg aatccgccca catcgatcaa ggcttctttt cgatacatcg tatttgctcc
    64441 actgtacgca taaagaccac cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat
    64501 acttgagaat tcaaccgttt gagattttgc aatcaatttg gtacgatttt ggacatccat
    64561 atttgcagtg accgcagcaa tatgtcttgc accagggcga atgaaataat tcacatacct
    64621 aatcagtgca tctggctccg gtaccgtgtc tgcatcattg cttaaaatca atttcccttt
    64681 tgcaaaggca agtccgatat taaacgcgtg ggcttttcct ttattttttt cgatccgaac
    64741 cacacgaaga ttagcgtatt ttttcatcag tctagctaat atttctggtg tttggtccgt
    64801 tgaaccatcg tctgtcacta atacctcata gttgtgataa ttcaatttcg tcatcaaata
    64861 ctcgattgta tcttcgatca caatttcttc attatgggct ggcaccatga tcgtgatgaa
    64921 cggttcgaca ctcaagggaa catctaccca ttctttttgc ttatgtttgt ataaaaacac
    64981 ataacaccag acaccaataa accatacaaa tccgcctaaa atcggataag aaacgagaaa
    65041 aaatacataa tagacaaaca agtatctaag aataaattac ctgtatgggt gattgagatc
    65101 atttcagttc caccccattt tctttataca aatctgcaat gaatgtcgta tctagatttt
    65161 tctcttcgga gacagaataa aaacggaccg tttctctctc ttcttttgtt ccaaaacgtt
    65221 ccgtatacac ttcttcaagt aattcttgtc tttttttcaa tttttcatct tcatattcaa
    65281 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
    65341 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
    65401 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
    65461 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
    65521 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
    65581 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
    65641 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
    65701 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
    65761 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
    65821 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
    65881 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
    65941 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
    66001 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
    66061 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
    66121 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
    66181 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
    66241 agtcgtcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
    66301 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
    66361 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
    66421 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
    66481 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
    66541 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
    66601 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
    66661 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
    66721 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
    66781 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
    66841 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
    66901 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
    66961 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
    67021 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
    67081 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
    67141 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
    67201 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
    67261 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
    67321 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
    67381 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
    67441 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
    67501 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
    67561 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
    67621 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
    67681 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
    67741 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
    67801 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
    67861 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
    67921 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
    67981 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
    68041 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
    68101 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
    68161 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
    68221 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
    68281 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
    68341 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
    68401 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
    68461 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
    68521 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
    68581 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
    68641 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
    68701 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
    68761 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
    68821 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
    68881 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
    68941 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
    69001 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
    69061 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
    69121 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
    69181 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
    69241 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
    69301 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
    69361 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
    69421 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
    69481 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
    69541 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
    69601 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
    69661 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
    69721 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
    69781 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
    69841 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
    69901 tggattttcc aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
    69961 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
    70021 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
    70081 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
    70141 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
    70201 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
    70261 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
    70321 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
    70381 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
    70441 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
    70501 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
    70561 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
    70621 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
    70681 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
    70741 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
    70801 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc
    70861 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
    70921 tttgaacacc gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa
    70981 aaaaacggga aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
    71041 tgattgaaca ccgtttaagg aagagattgt gaaaaagtcg cttagtttcg agtattaaga
    71101 aaaattttgt gaaaatggat ttctacattt ttgcataaat ttggcttaat accgagaaac
    71161 tggcttttga ataccgttta aggaagaggt tgtaaaatca gcggtttgac ctgagtatta
    71221 gagaaacaaa cggaaaaata gctgctcata ttttgccgtt ttttgagcta ataccgaagg
    71281 tcagctgatt gaacaccgtt taccaagagg ttgtgagcct accatttaac tccgaatcac
    71341 aagaaataat ttcaaaaaca acttctcctg tttttggttt ggttggctta ttatcgagaa
    71401 gtagctactg ggagtctatt tatcaaaaaa aggaatgcga cataggtcac accccttttt
    71461 tattttcttt gaaacatctt tcggtactcg acagcataca agacaaaaga ttgtaaaaga
    71521 ccgtaagtga tgacggcaaa aatgactctc acccacagcg ttggtaattc tgggaaaagc
    71581 agcaaaagga tcatgccaac atagatgaca gcagtcgcta ctttgccata ccacttcgct
    71641 ccacttaatt tgatattttt agatagcccg attaatccag ctacaaacat aaagccttct
    71701 tttatcaaga atagaccaaa caacagccaa agccacggtc gataccatgc catagacaaa
    71761 atcagaaaaa gttgtgtcaa tttatctgca aacggatcaa gcaccttccc taagtctgtt
    71821 acctgattat atctccgagc aatgaccccg tctagataat cagacaaacc tgagacaaca
    71881 atgaccgctc ctgctatata aaatgactgt ctcagcacaa aataaagata aatcggcagc
    71941 aaaaaaatac ggaatatcga taaaagattc ggaatcgttt gtatttcttt acgccagtct
    72001 gtgcttaatt tcattttatc gccctacctc ctcagcactc ttttcttttt attttagctt
    72061 acacggggaa taaaaccaat gatttcactg tttttatttt tctttacagc cactgatatt
    72121 atgagctaat ttgagataat cacttgctgt tttcatcgtt tactcttctt tcttcctgtc
    72181 gtttgcgcat ttcttttact agtactttat gagctttttt tgatcctcgc tctaggtcac
    72241 gctgccgttt acgtgtttta taatcgataa acagactgtc taaatcgtaa cctgtcgggt
    72301 acagatcttc tgctgaacgc accagacgaa cacgctgacg aggcacgtgg attatttttt
    72361 tgtctaaata tacatcaatc gtatcttcac ctatatcttc ataaactaac gcttcttttt
    72421 ggtattcatt gacaaatatc cgatcacctt ttgcaaagag ctggcgttct tttttattct
    72481 ccttcctatt tgtaactgct gtcttaggaa gaaattcttt tttctgtgtc cgataggctt
    72541 tttccgccaa gtaacgctct gcttgatgga tcaatttcat cgacatatcc attttatgag
    72601 caatccacaa agcttggctt tctcctgttt ctccaacccg caactgatat ttaggacgaa
    72661 gtgcttcccg atcgaaagcc atagcagccg gcacaaaatc ttcatgatct ccggcgaatt
    72721 tcttgatttc tccataatgg gtcgtggcaa tgatcaatgc cccttgctca tacatagatt
    72781 ccatgattgc gatcgctagt gcagcccctt catttggctc tgttccactg ccaatctcat
    72841 ctaaaagtac caacgtattc ctttttatct ttttcaaaat agcagcgatg ttttgcatat
    72901 gaccagaaaa tgtactcaac gcattttcta aattttggtg gtcaccgaca tcgacgaaaa
    72961 tctcatcaaa gacagcaagc tctgtccctt cttttgccgg aacttgcata ccgaacatcg
    73021 ccatcaaagt caataaaccg actgtcttca acacgactgt tttgcctccg gcatttgctc
    73081 cggtgataat caagcctcga tagtctttac cgatttcaac atccaatggt accgcatgct
    73141 caggtaaaaa tggatgtctg ccttgcttga taatgatatg ttccgattta ttgattctag
    73201 gtgtgcttcc attgatttct cggctaaatt ttgcccgagc aaagatgata tctaacaccg
    73261 tgatcgtttc gatcaataaa tcgatcactt cttcgttttc tgcgatagca ccagtcaatg
    73321 ccgccaggac ttgatattct tcactgattt cttcagcttt taacaactga tagtgttcat
    73381 tcaatttaga aatcacagtt ggttcaataa aaaccgtcgt tcttttattt gattcatcga
    73441 taatcgttcc atctatttta tttttatagc tggctttgat aggaatcgta tagtattcgc
    73501 ctttttgaac aatcattgct tcttggatca tttctttgtt tttcggatga cgcaagaatt
    73561 tcagtaattt tgactggatt tctttttcga ttagttgtaa ttgtttgcgt actttacgca
    73621 aattacgtga cgcgtcgtca ctgactttat tattttttat tttctggtca atcaactctt
    73681 ctacatttat caaatcagga agatgtttgc tataagcaaa caacaagggt gtctggtatt
    73741 gattcttatc aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc gcatattcga
    73801 tcaaatcggt tggctgcaga atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc
    73861 tcggcaaccc cataaatgga acatgctgac tgctttctaa gatcaagcgt gcttctcttg
    73921 tttcttcttg acgatccaag acagtttgta ggtttgtcga gaccgtcata tcgctgattc
    73981 gttttttgct atagtttcca attgctcttg cttggatttc ctttttgatc cgatcaaatt
    74041 gtaattgact aatcatttcg ttgtccatat tctctccttt tcttgaagag atacctgtcc
    74101 caaaataaat aagggcctag agataaataa aaggatagaa cacagcttaa aaaagtcatg
    74161 tcctatcctt attagaatac aaagatattg ttttcctgac aggtaccgtt tcataagcac
    74221 accaaataaa ctttgtttat tggctattcg acttactgat tagataccag ctacactcac
    74281 aaaacatacc ccattcttct aggtcttatt tattttccac ttaactatag caagacacat
    74341 tttggttgtc aaactttagt atgttttata gatttacacc attaatgaat agacacctac
    74401 cgcgataatt gctccgatca ttggacctgc gattggtacc catgaatatg cccaatctga
    74461 agttccttta ttagctattg gcaataccgc atgtgctaat cgaggaccaa agtcccgagc
    74521 agggttgatt gcatatcctg ttggccctcc taatgaaaga ccgatggcta agatcaatcc
    74581 acctacagcg aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc
    74641 aagaactaat acaaatgtac caattaattc tgtgatcaca tttgctggat aattccgtat
    74701 agcaggacct gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg cattccaatg
    74761 tggcaaataa gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat
    74821 gatgaaagga acgacaagat tccaactaat tgcccctgtc atcgccatag ctagagagac
    74881 tgcaggattc aaatgagctg ggcccatgaa tccagaaata tagacagcca ttgttacagc
    74941 gagtccccaa ccaaatgcga tgacaatcca gccagaagcc tgtgctttac ttttgtttaa
    75001 attcacagcc gcacacacac catctccaag caaaactagg atcagtgtcc caataaactc
    75061 tcccatgatt tgagtcatat cactgttcat ttatttctcc ccctttagtt cccgcagatc
    75121 tgattctgca atcaatgctt ctaaacgttt agtctgttgc gccttctcct cttctgtcca
    75181 ttcaaaatat ccagcaattg catcgatcac aggttgcttg atctcatcaa gctgatctcg
    75241 ttcaaacaac agatgatttg tacgacgaat gagataatcg cctggggcca aaaccatttc
    75301 ttcttctaaa ccataacgta accgagctga ctcagcgaga ctcaaaccag gataaggtgc
    75361 catttctttt gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat cagcgatata
    75421 agtagcatct tcttcctcta aaccggctgc tactccttct tttgctaatt ctgtcactgt
    75481 ttcttctaat ttagttggat cgaagtttcc acctgaaatc tgatattttt tagagtcgat
    75541 ttctttcgtc tctattccgt attcttcttt taataattgg cgtatcaatc gcaaagctcc
    75601 ttctgccatc ttacggtaat cggtgatttt cccaccagat aaagtcagca aaccatctgg
    75661 ttctctttct aaagaactac ctctggaaat cgtagaaggt gctttttcat cacggctgtt
    75721 ttccaaatgg ttcaacacgt cttctacttc agcacgagaa actttgtttt ccttatattc
    75781 acttactgta tcgacaactt tattgaagct cttgtctgaa atcgatccat tatctccacc
    75841 attgtaatca gaaccagaat taccaatcaa cagtggacga agtcctgccc agcttgcttc
    75901 gatatcattc aatgtgatat ttgcttctgg atagcgatga ttgatcacat ccaatagata
    75961 atctacatct tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt
    76021 cgtaccaaag taagtcttgt tttctcttgg aatagcaaaa accatccgcc catcttgctt
    76081 tcctgtatcg aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta caactaaatg
    76141 gatcccttta gttggacgca ttttaggaga gactggacgc gtaaaattca agtttcgtac
    76201 tttatctacc caaggaccac tcgtattgat cactaatttt gctttgattt cgatcacttc
    76261 atctgtcagc aggtcacgag ctttgacgcc aacgatttga tcgccatcat ataaaaagcc
    76321 aaccgctttc attttactta ctagataagc cccatcttcg gcagcctttt tgatattatc
    76381 aatcactaaa cgggcatcat tgttgcggaa atctagatag acacccgcgc cttttagccc
    76441 ttcttttttc aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg tataattctc
    76501 atatttggtt cctgtcacat ttgccagttt gtcataaagg tccattgcta ctttgaccga
    76561 gaacatattg aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg
    76621 ttttgggatg tgtggggcaa tactttgtac gactgcacgt tcaccaactg tgtcagctac
    76681 tacttccaca tcaaatgtct tcagataacg aataccgcca tgaacaagtt tggtcgagcg
    76741 agaggaagtc ccttctgcaa aatcctgcat ttcgatcaat cctgttttga ttcctgatgc
    76801 tgctgactgg actgccacac cggcaccagt gattccgcca ccgatgatca acagatccaa
    76861 ttcttcttgc tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat
    76921 ttcctcctta ttcaaatgct tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt
    76981 tttctcggcg ctcttcctcc atttgaactt caaatagctt gccagcttca taaaattcgc
    77041 ggatctcgtc tgtatctttc caataaccga cagctaatcc tgctaaaaat gctgccccta
    77101 gcgccgttgt ttccaagttt tctgctcgtt ggatcggtac attcaagata tctgtttgga
    77161 attgcatcag atattcattg tttgctgcac cgccatctac tttcaataca ggaatcttga
    77221 ttccagtgtc atcttgcatc gtatcgatga tatctctcac ttgataagca atcgactgta
    77281 aagtagcttt aatgatatct tcttttgtcg taccacgtgt caagccaaac atagcccctc
    77341 gtgctgcctg atcccaataa ggagcaccta gcccaacgaa tgcaggaaca acataaacct
    77401 catcttcgct tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt tgcaacattt
    77461 gaagtccatc tctcagccat tgaatcgaag aaccagccac aaaaatactt ccttctaaag
    77521 catagtaaac ctttccattt atgccgtaac caattgtcgt caataaatta tttttggata
    77581 attgcggttt ttcaccggta ttcatgacaa taaatgaacc tgtaccataa gtattcttga
    77641 ccatgcctgg ttcgaatgcc atttgtccga ataatgcggc ttgctggtct cctgccatcc
    77701 ctgaaattgg tgcttcgctt ccataaaaat gataaccttg cgtataacca taaacttctg
    77761 agttagaagt gacttttggt aacatcactc gaggaatatt tagtaaatct aaaatctcct
    77821 gatcccaatc tagctgatgg atattgaaca acatcgtccg actggcattc gagtaatcag
    77881 taacatgtgc ttgtccatcg gtcagtttcc atactaacca agaatcgatc gttccaaaca
    77941 tcaattcgcc tttttcagct cgttcttgcg cgccttctac atgatcaaga atccagcgta
    78001 tcttcgttgc tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt
    78061 gatagccttc attttttaag ttatctgcaa ttccagctga ctgtctggat tgccaaacaa
    78121 ctgcatgata gattggacgt cctgtatctt tttcccatat tactgttgtt tcacgctggt
    78181 tcgttatgcc aatcccagca atctgatttg gtttgatccc tgattcgatg aacgctccgg
    78241 caataactga ctgtacagaa ttccagattt catttgcatc atgttccacc caactttctt
    78301 gcgggaaata ttgcgtgaac tctttttgag aactgccgat gtgtcttcct ttcttgtcaa
    78361 agataattgc tcgtgagcta gttgtacctt ggtcaatcgc catgatatac gttgattctg
    78421 tcattgtgat tccctccatt atatgcaaac gctttcttta actactctta tcatactact
    78481 gttttaaaaa aagaaactgt caaaatttta ttcttttttt ctttttttga cagtttttta
    78541 ttatgaagct attttttaat caattctttt cttttttcag cgtctctatt cttcttttca
    78601 atcgaataat gtcgtaaggt gacgcaaatt ctgacagata atattcacac tgttttttgt
    78661 ttctctggca aaatgtgatc accaaatcat attctttacc ttcttcataa cttccaatct
    78721 caataccgcc gattcccctc agttctctga tcagatattg ttgaaaagca atacgataaa
    78781 tcggcagact ttctaaatcg attccaatca ctactggttt tgcaatataa aaatcgatca
    78841 tcaaaagaac attggcatac tggatcatca ggtaactaag ctcactatct tcagctcttt
    78901 tcctcggcaa ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt gttaaggaat
    78961 gcccgagcat tttctgctgc tgttccaaaa gccgatcacg ctcatagact tcgatctttc
    79021 caacaaagaa aaaccattca ttgttgatct gggaaatttg gtagcctact gccttttctt
    79081 ctttgatttt caaacgacga ggacgataat gccataacat cgtttcccga atgtaagtat
    79141 ctaaaacagc ggttggtaac tttttgctcc gtgtcaaatc atactgataa aatatttctt
    79201 cgtctactat cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg tatacattca
    79261 gttctgctgc tgttcgacta agatgcatca cgatgattgg atcgattgct tgataaagcc
    79321 ggtccgactg atagagtaat ttcttttctt tcaaagttgc gtacgtactt ttttcattca
    79381 atagtctttt tttcgtaatc ccgagccagc aagcaatctg tgcttctgct gatgccgtaa
    79441 acgttgtttc taatacacgg tccaatccta gaatgaacgg tcttttttct ggtgtatttt
    79501 gcaaaaaaag cggtcgctga tcttccggga tatattggaa tagttcataa taaaaatatc
    79561 gtatctgtag ctcttctccg tataattgac cgtttttgat ttgtaatcca aattcctcta
    79621 agagctggtt caattctttg atctttcgaa aaacagaaga ctcactgata ttaaacgctg
    79681 tcgctaatcg aacgatggat acttgctgat gttctaataa atagacgagc atcttaaact
    79741 tcaagctttc ctgcaataaa aacaatagaa ttttttccaa acttacatct tcgtccaaca
    79801 caagcagcgc ctgatactca tttcgctgta cttctacttt tttttccatc attcggccaa
    79861 tcaattcaat atcttccaaa tattgatcaa acgaggcttt tgacagttgg acatgctctc
    79921 tcaaaccatt gatagaggct gttccccctt gcagaacaag gtttcgcaaa atcaggatct
    79981 gtaactgctc ttttctttct aataatgctt caatcttcat aggcagtatt cgccaccttt
    80041 gaccacacca tatctggcac acggtattct ggctggaaaa atagctcatg ttcttctaac
    80101 tgttcaaacg tccatccttc ttctactgca attgtcagtt ggtcaagaag gtggaacatc
    80161 tcttttttgc tttggagctg tgctccaaga atcttttttt cagaatcaaa tagaaatttg
    80221 agtttaactt tgctttgatt tattgctgta agcttgtagt ctacgtatcc tgtttcaatt
    80281 ttttggggat aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca
    80341 aaccactgat tgccgactgg acgataggtt ccctgatcct ttgtctgtga gccactaatt
    80401 gtcttgctga catttcgtgc tgtacggaca gcgttattta ctagagaaac atacattttt
    80461 tcatttgttg gacgaaaagt tacttggatc gcatcgccaa tcgcataaac gtctttttga
    80521 gacgtttgca agtagtcatc tacccagatc gttccatcat cattcaatgt taattgttct
    80581 tcccacatct gattgtcggg gcgagaatga ttagccagca aaacaagatc atagttctcc
    80641 tttctttttt ccgtctctac aatagcggtt tcattttcgg tcaaagacac aacttgttct
    80701 tctaaaaaaa gtgaaagccc ttgatttttc atttccttta ctaacggttc tgtcatttca
    80761 ggatctagat aacgaaaaag aattgacttt cggctttcgt aaagatggat ttgttttttt
    80821 cttgatgcca acccttcagc tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt
    80881 ttctttgcat tcatgatctt ttgctgaaga gccgttacgt tttgtatctt tttaactggg
    80941 tgaataagcg ttgattctgc agaaatattt cgaaactttt gatttgaacc agtcgctaga
    81001 atcaaacgat caaaatccaa tttttttcct cctgctaaaa cgactttttt ttctttcaat
    81061 cctattactg tcttttctgt gtaaacatgg attcgatagc ggtcagtcag ttcttctttc
    81121 gtgatccaag aaagttgttt ttcactggta acctttcctt ttaatatcaa attgaacccg
    81181 ctgggaatcc atcctaactt cgattgcttt tcaatcaaat atatttcact tgttggcatc
    81241 aattggcgaa gataaatagc cgcatgaatc cctgcaaacg acccgccgac aattacaatg
    81301 ttcatctgca ttcctctttc ttataaggtg ttctactgct aacttctcaa tcagaaaaca
    81361 cagtattcat aactcgcttt caaccttatg atacatagcg atgcagcaga atcaaccctc
    81421 tccatcatac cgtgttctag gtctgcttct caataatgta ctagtggacc taattgaaga
    81481 gtatcatttc tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct
    81541 tttacgtacc tctgtccaaa taggaaacag aaaagaacga aaagacgagt tttagcgtgt
    81601 gtaatgtaat agttagaata gacacatcat ttatttttaa ttctttaatg cttcaacaac
    81661 tgcttcgcct aattgatgag cagattgagg attttgccct gtaagaagcc gcccatcaat
    81721 ttgaaccact tctgaaaaag ctgctccaga ctgatagttt gctccttttt ctttcaaagc
    81781 atcttctgct aagaatggta cttcattcgt tgtaccattt gcttcctctt cttcattact
    81841 gaacccagtc actgtacgtc cagctaaaat agattttcca gactcatctg taactggcaa
    81901 caatcctaca acaccgtgac aaacagctga gaccagccct tcatttcgat agatttgtga
    81961 agcgactttc ccaagatcta ttgcttctgg aaaatcccac attgttccgt ggccaccagc
    82021 ataataaacc gctgcataat catttgcatc cacatcatca ggacgtaagg tatttcccaa
    82081 ggcccgattt ctgaaatctt catcttcata ataggcccaa tcgatttcat ccatattcaa
    82141 aacactttgc ggttctaaag gtacatatcc gcctttagga ctgacaaaat ctgcatcgat
    82201 cccatttttt actaatacat cataaaaatg agtcagttca cttaaccaca aacctgtagg
    82261 acgctcgatc ttttcgtact tttctacatt tgttaatacg atcaatactt tcattttccc
    82321 atcctctttc tataaaaatt gcgttattga taacgtgctt tcaagaaatt atataatggg
    82381 cttggcaaat aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca
    82441 cggttttcca ataatttctc tgcccagtca ggatcgacga tcatttgctg tccaattgct
    82501 gcaagttctg catatttcaa tacctgctct acatcttcgc gattgcggat cccaccgaca
    82561 ccaactaaag ggatctttcc ttgaatcgtg ttatggacca cttcaagaat cgatttatcg
    82621 ttgtatttat cagaacgagc tattcgatca tacatattta atgaaacatg cagataatct
    82681 agttttgact cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt
    82741 gtttcatatt cttctggtga gaaacgatac cctacgatga atggtttttt agcatattgt
    82801 tcaaccgctg agaaaaccgt tgttaataat tcttcaataa aacgataacg attttccaag
    82861 ctaccgcccc attgatcctc tcgtctattc gaatgcggag agaaaaattg ttggatcaaa
    82921 tacgtatttg ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg
    82981 gctttgccaa atgcttggat tgtttcaacg atttcttctt cactcattgc tcgtggtgtt
    83041 tccgcatcag gacgttttgc tgcaactgca cttgcagata caggctgttc tccagataaa
    83101 gttgctcgac ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct
    83161 ccttggattg ctttcgctag ctcacttaat cgaggaatca tttcatcatg agcgatgctg
    83221 agttcacctg gccagccttt tccgatatct tggacatttg cagcaccagt aataacagca
    83281 ccaagacctt tagaacgttg tttataataa gtgatctcat cttcggtgat cactccattg
    83341 aaaaagctga gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa ttgaactcct
    83401 gaaggtaaag taattgattg atcaaattgt gacattgtca ttcctcccat aattcgctct
    83461 gattaaccta tcgagaatca tctatcatta aaccactcga ttagttgtac atgcaactaa
    83521 tttgcttaaa aaattttatt ttttttgtaa cttatctgtt gcatcattca ttgtctgggc
    83581 taattcttta cttgcttcat ttcccaaaac tgctttgtat gactgatgaa gttcttccca
    83641 gctaccatcg acttccttag caaattggcg tccttgttct gtaagataaa ctaatgacaa
    83701 gcgaccttcg ctaactgttt tgacgtatcc tttatattct aatttttcaa caaaacgagc
    83761 aatcgttgat ggggcggaat agagcatttg tgcaatatct ttttgtggta ttccatcttt
    83821 ttcttttaat atcaataaaa taaaaccata agttggtgcc agacctgtcc ttctaaacgc
    83881 ttcatcagct aatttattca acatgcgatc tagctttttc acgctaaaga aaagacattc
    83941 atctaacgct ttttcaattg gcttttccat ttcatcccct ccattggcgt acatatcata
    84001 gtatgatttt tattttttgt caaaaaacac ggaataatgt ccgcctcctc tgtctagatt
    84061 tgaaaaaaag aagtagccat cttcaaagaa tttcggcttg ttttcgacaa aactccttct
    84121 ggaacaccgt gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt
    84181 ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgaa aaactggctt
    84241 ttgaacaccg tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca
    84301 gccaaacaaa aatagttcct catattttgt cgttttttga gctaatgccg atggtcagct
    84361 gattgtacac cgtttattga gaggtcgtga gcctgccgtt gaactccgag tcacaaggag
    84421 caatttcaaa aaacagcttc tcatgtttta tgactatggt gacttgtgat cgaggagttg
    84481 gcaggagaat actgtttatt cgtaaagaag gggctgtgac aagacttttg tcacagtccc
    84541 ttatttcctt ttattatagg atttcgccat ttgattggat gacttgtctg taccaatcaa
    84601 atgatttttt ctttaaccgt ttctttgtgc cattcccttc gtcatcttga tcaacataga
    84661 tatatccata acgttttgac atttgtgaag tagaagcgct gacgatatca atgcagcccc
    84721 acgacgtata accaaataaa tctactccat ctttgatagc ttccttcatc tgctcaatat
    84781 gctgtttcaa atagtcaatg cggtaatcgt cttgaacggt tccatcttct tctactttgt
    84841 ctatagctcc gagtccgttt tcagctatga acagtggttt ttgataccta tcatataatt
    84901 gattcaaagc aattctcaaa cccttaggat caatctgcca gccccattca cttgatggaa
    84961 gatacggatt tttaattcct ccagttatta agtttccttg gaccccttcc caattttctg
    85021 gatgagcact gactgcacta gacatgtagt agctaaaaga aacaaaatca acagggtagg
    85081 ctgctaagat ttcttcatca cctacttcta tttttaagtt gacacctttt tcttcaaaca
    85141 ttcgttgcgt atacgctgga taatatcctc ttgcttgaac atcactaaag aacaaagaag
    85201 ttctttgctg ctcaattgtt ttttgaatat catccggatc acaagaatac ggaacaagaa
    85261 gctgatagct gatcatacaa ccgacttgtg aacctttgat aatttcatga caagcttttg
    85321 tagctaaagc acttgctata aactgatggt gtgcaccttg gtatttcgct tgttccaaat
    85381 ggggatggtt ttcttcaatt actcctacgc taacaaaagg gtgatgtttt acacagttga
    85441 tctcattgaa agtcatccaa tattttactt tatttttata gcgtttgaat actgtttcag
    85501 cgaaacgaac gtaaaactga ataagctttc gattaggcca tccaccatat tctgtaacca
    85561 aatataacgg catttcataa tgggaaagag aaacgactgg ctcaatccca tattttagac
    85621 attcgtcaaa cacttgatca taaaaaaata atcccgcttc attgggtgtt tcttcatcac
    85681 catgaggaaa aattcttgtc catgcgatag acatccgata gcatttaaaa cccatttcag
    85741 caaataaacg gatgtcttct ttaaagtgat gatagaaatc atttccgtgt cttttaggat
    85801 aataatactt gctgttggga tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc
    85861 attgatctgt ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag
    85921 ataatccttt ttcatctaca tcccatgcac cttcacattg attggccgct gtcgctccgc
    85981 cccataaaaa tccttctgga aattttttca tatcgatccc cctaaacttg ctagttttct
    86041 tgtttgatta tttttcttat gactagtaat gatatttttg aatctactac tatttgtaac
    86101 aataaccatt gtggtcggat catatccctc tttgattaat tcttgcaaat ctacttccat
    86161 caataaatcg cctttacgta ctttttttcc atcagatact gcactttgaa agtatttgcc
    86221 atttaaattc actgtatcaa taccgatatg gatcagtatc tctgctcctt cttcactgac
    86281 taccccaatt gcatgtttcg ttggaaaaac tgttgaaact tccccgttta caggactgta
    86341 gatttttccg tccgttggaa tgatcgcaaa cccttctcct aaagatccac tagcaaatgt
    86401 tggatcgttt acttcagata aatcaattat ttcacctgct gcaggagtac ttaacactat
    86461 atcctttgag gattcttctt cgatttcatc cttgtagccg aaaagaaaag ttagcataca
    86521 ggaactgatc atcgctaaga aataactagc aactagccaa acaaatcctt caccaatata
    86581 aatcgggaaa gacaaaatac ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc
    86641 agctactcca ccaaatatag ctccacatat acaagcaatg taaaatggtc gtttatattt
    86701 aagagtcaca ccataaacag caggttcagt gattccaaat aatgctgtga taaatgcaga
    86761 taaagataaa ctttttactt tcttattttt cgttttcaaa aataccccaa gtactgctcc
    86821 tgcttgcgca gctacggcag tcatacatgc tggacctagc gtatcacgac cgtagaaaga
    86881 aagattgttg gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg
    86941 ccaaaatccg ccgataacag caccagataa aacagggcta aagttataaa cagctaaata
    87001 tccagctgca atcagctgac ttgcataatc tgcaattgga cctacaacta ataaagtaat
    87061 tgggaccatc acgatgatac aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa
    87121 gcttttgcga atcttaggct caatataaga aagaacccat acagctaaaa ttgctggaat
    87181 aaccgtactt gtataccttg ctagaatcac gggcatccct agaaatcgca aggttatgct
    87241 atcactatat gcactgacaa tcgtaggata aacgagagct gctgcaataa ccatagcgat
    87301 gaaacgatct gtattgaact tttttgcagc agtatatgcc aaaaatatag gcaagaaata
    87361 gaaaaatgca tcagctgctg cattcaaaat gatataagtt cctgattcag tagttaataa
    87421 attcaaactc gtacataagg cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc
    87481 taaagtcggg gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa tgcctttttt
    87541 ctcagttcct ctctttccac tagatgcatc atcttctagt ttcatttgtt tggataatac
    87601 gtcatacact tcatttactg catttcctac tacgacttga aacattcctc cagcttcgac
    87661 tacagtgatc acaccttcta gttgctctac cttctcctta tctgccttct tattatcttt
    87721 tagggtaaag cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc
    87781 gacaaatcgg acaatatctt tcgctaattg tgaatagtcc atttttactt cccccttgtt
    87841 aattaatgcc gtagcaatcc ttcttacaag ataagtatag ttcttagaaa acggtttctc
    87901 cattcaatta gtacccctta taatagcgaa cgaaactgta caatagtgtg tatggtttac
    87961 ttagccgagc aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc
    88021 aaaggagaca aaaaaaacac gcttgatctt cctttgctga tgtataagtg gtatctcaag
    88081 ctgatactct gtgatttttg tttctacttg gcttttgata agacagcaca acaaagtctc
    88141 ggcatttaac ggaagcataa ctaggtcaga actaggagag attagttgct gaatggaatc
    88201 tatcttttta tggattttta tttgattttc ttctttgtag taatgatcaa gcagttttgt
    88261 tttctttttt tcttcaacta tggtcagctt ttcacgcaaa atctgataaa tctcccaaga
    88321 ttcaaactca tctagaacac taggtagata aatcaaatca tcccactcaa aaataagctc
    88381 ttgctcagta gtcaaaattg catcatattc cgttattttg tttgattgat ttttgaaaag
    88441 atacactggt tctatccggc attctttgat ccacatgttc atactttgtt gaatctgttt
    88501 ttttagtgta ttcaaaatac taattggctg gttactaaca atcagtatct ccccttgttt
    88561 tcgaaaagga ttcaacgctt cggcaagata caaaacaaaa taagcgcttt cagctaaatt
    88621 gggacgtaat tgaaaatgta ttgggaagaa acgccgaatt aaataaattt ctaaaggata
    88681 acgggagatg atcttttgta caaaatgatt catggtatta tgtccggcat ccatcctcgt
    88741 tttcatttgt ttgatatggg ttagcaaaaa ttctgtttca tggaacaata acgaaacagg
    88801 aagatctaaa aaacgaataa tcgtttgctc aaatgctctt agattcttct ctatttcttt
    88861 gtttttttca tcattaatca tcaaataatt taactctaat agtcgatttt caattgcttg
    88921 tttttcttga ttggaaaaag aatagggtag ttctgatgat aacttttttg tgagggtctc
    88981 taccatcgga ataaataatg tatacctgtt tgttttttct aaaagttctt ctcttcgaag
    89041 aatggtcaaa acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa caatataatt
    89101 atatgatata agaacctctt ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat
    89161 tgtactgatt tgttgaggca accttgcgtg ttggatcacc gtttctgttc caacaagaga
    89221 taagaaaatt ctttttgaat tttcttcagc aatgattttt agtccttttg tcgacgaaac
    89281 ttccagttct aatttaggat tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga
    89341 tacggctgtt tttgaaagaa agaaaatgtc tgctatcttt tgcatactga catacccttt
    89401 ttgaaacaat aagtacgtca caatagttga agctcggaaa tccatgctgg aatagatttt
    89461 atgtttcgtc acctcttgta tgatttgctg tttagtttca gattcaattg attctaaaaa
    89521 ataacctgaa cgtttatttg actggataat gattttcttc tcgtagatag caagcatatt
    89581 tttgatttca gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta attcttcgct
    89641 tgttatccaa tgattcttat ttcttaatac tacaagaatt tggagttgtc gtttatttaa
    89701 gtccatttgc ttacacctcc tctttgttat aaacatacag gaaaaacctc tcaaatgaca
    89761 atagtcactt gcagaggttt aaaaatcatt tgaagaaaga tctatattca aggtttttac
    89821 cattagactg gataatttgt ttataatatt caaaactatc ttttttcaat ctcctaaagc
    89881 ttccgctccc atcattttgt ctatccacat aaataaagcc atatcgcttc ctcatttccc
    89941 ctgttcctgc cgatacgata tcgattggtc cccaccataa gtaaccaatg atttggcaac
    90001 catcttttat tgcctcagca atttcctgaa gatgtatttt tagatactca caacgttttg
    90061 gatcgtggat tcgattcaat tcatctggtg cttcatctag tccaatgcca ttttcaacta
    90121 tgaataatgg taattcataa cggtctgtca attcattcat gacataacga aaccctagag
    90181 gatcaattgg ccaactccaa ggttcgggag atttttcctt caaaaaggga ttatcgaaac
    90241 catttgctcc gccagtatct acgcgcattt ctgcttcttt tttatagaca gcgctacgat
    90301 aataactaaa tgcaatataa tctgccgtgt tagcttgcaa gcactgttcg tctccatcta
    90361 acattactgg tgcacagtct tcttccttcc atgtcctgta aatataagct ggataatgcc
    90421 ctcggcacat gacatcggag aaaaaccatg aattgcgttt aaattgcagt gaaccaaata
    90481 cattctctgg atcacagtca tatgcataag tcgctaatgc agaaaagcta cacataatac
    90541 ccatcttagc atttggatcg attttcttta ataattgagt agcacgggcg ttcgctagaa
    90601 acatatgatg acaggcttga taaatcactt tttttgttag tgtagcaatg ggttcaagtt
    90661 tatctctagc agggaatgta accaatccag cagctgcata aggcatacga aaagcattat
    90721 tgatctcatt aaaggtcatc caatatttca ctttcccttg gtagcgttca aagacggtct
    90781 gcgcataaaa ttcaaaaaag tcgattaatt ttcgattttg ccacccccca tactctccta
    90841 ccaatgctaa gggggtttca taatgactaa gagtaattac tggctcgata tcatatcgat
    90901 ttaatgtatt gattagtctg tcataaaata cgagaccagc ctcatttggc ttctgttcgt
    90961 ctcctcttgg aaatattcgt gcccatgaga tgcttgttcg aaaagctttt aaacctaact
    91021 ccttcagtaa acgaatatcc tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa
    91081 gataatggag tgattcgtct aaagcaatct cccaaatctt tttttcttca ttccactgaa
    91141 tactaggatg ctggttcatg atcccgataa gcgtatctgt cacattaggt aatttgccgt
    91201 cttccaacca tgcaccttca cattgattag cagctactgc tccgccccat aaaaaatttt
    91261 ctggaaatat ttcctgatcc ataactatct ctcctcgcta tcaacaattt cttacttgaa
    91321 gtatagctcg attcatcaaa acaagatatt ctaactattt cggcagaaga gaagaaaaaa
    91381 attgaatgct actcttcatt tttaatattt atatataaca aatacataag acgatccccg
    91441 aaagaaaaca ctcgttaacc atctaagcaa acgatttatt ttacttccaa cacaaatgct
    91501 tcataaggtc gtaaatcaac tttgccgtct ggtaactgtt tcagaggata atttgacaca
    91561 ataaccctta aagcttcacg tggaacagtg aacgtctgct tttcactgga catattacaa
    91621 ataacgagcc attgctggtc ttcatatatg cgagaatagg caaagacatg ctcaggcgtc
    91681 ttttccacta attcatagtc tccccagacg atgatgtcat gttttctacg caaatcgatc
    91741 aatttcttgt acatataaaa aacagaatct tgatctgcta acgcttcttc tgcattgatt
    91801 tctttataat ttggattgac tcgaagccat ggaattccag tagtaaaccc agcatgttca
    91861 cgggcgttcc attgcatagg cgtcctagca ttgtctcttc ctttcgcatt gattgattcc
    91921 aagatttcct cttttgtaaa tccagaagaa atcctttcgt tatacatatt gattgtctca
    91981 atatcttttg cttccgcgat atcatcgatt gggcaattcg tcatgcctaa ctcttctcct
    92041 tgatagatat aaggggtgcc tttcatcata tggagcaaga tagcaaacat cttggcactt
    92101 tcttttcgat acacatcgtc atttccccaa cgagaaacaa ttcgcggaag atcgtgatta
    92161 ttccaaaata aactattcca tccttcatca cctaaagatg tttgccattt ggataatact
    92221 tttttcagtt cagagatact caagggtttc aaatcccatt tgtctttgcc ttcttgctga
    92281 tctaatccta tgtgttcgaa ttggaagacc atggataatt catttctttt aggattggaa
    92341 taaagtttag cgatttcggt agttgctccc catgtttcgc caacagtcat cagatttttg
    92401 tcaccaaaag ttgcttgatt catttcctga agatactcat gcagtttagg tccattactt
    92461 gtgatttctt tatccggttc tttgccaatc atatcgatca cgtccatacg aaagccccca
    92521 atacctttat cgatccagaa attcatcatt tgataaatct cttggcgaac ctgtttattt
    92581 ttccaattca aatcaggttg acgcttgcta tacaagtgca gaaaatattg ccccgttttt
    92641 tcatccaact gccaagcaga accactgaat attgagcgca atctattagg ctcttttcca
    92701 ttgaccggat cacgccaaat ataatagtcc cgataaggat tttctttatt tttacgggcc
    92761 tcaatgaacc acggatgttc atcagaagta tgattcacca ccagatccat gatgatacgg
    92821 atatttcttt tctttgcttc ttcaatcagt tcttccattt cttccatcgt accgaattct
    92881 gccatgattg cttgataatt actgatatca tacccattgt catcattcgg agactcgtat
    92941 actggagaaa gccaaattgc atcaatacct aaatacgcca gataatccaa cctggaaata
    93001 atcccccgca aatctccaat accatcttga tttgaatctt gaaaacttct tggatagatt
    93061 tgataaacaa ctgaatggtg ccaccatttt tgttccatga ttttcctcct ataaatggat
    93121 gtttctattt tttgcttaat catttatttt agtctctctc actaaaaatt gtaacgcttt
    93181 caaatagcta ttgcaccttg ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa
    93241 ttccctcaac tgttttttga aaggattgat ttatgcaggg aagaatgctg atttcacaac
    93301 ttctttataa acggtgttca ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat
    93361 atgaggaact attttttcgt ttttttctct aatactcagg ccagaacact gatttcacaa
    93421 cctctttata aacggtgttc actcagctgt ccctcggtat tagctcaaaa aacggcaaaa
    93481 tataagaaac tattttttcg tttttttctc taatactcag gccagaacgc tgatttcaca
    93541 acctctttat ttcacattca atatccacat gaatcccaca aatacaaaga acagaccata
    93601 catgattgga gatacttctt ttcctctttt agctgctaac atggtaattg gatagaagat
    93661 aaaacctaat gcaatcccat ctgaaatact ataagtcaaa ggcatgccga tcaagatcaa
    93721 gaatgaaggg atcgcaatct ctaagtttcc ccattcgatt tgtcgcaaag attgtgccat
    93781 caatactcct accataatca atgctggtgc agttacttgt gaagtaacaa ctgatagtaa
    93841 tggagaaaag aacaagccta acaagaagaa aatccctgta gtaatagctg tgatacctga
    93901 acgtcctcca acggcgatac cagctgatga ttctacaaat gcaccaacag gagaagtacc
    93961 aaataaggaa cccgcaagca tagctgttga atcagaagct aaagctttcc ctacacgagg
    94021 catcttgttg tctttcatga aacctgcttg gtttgctaat ccaactaaag ttcctgctgt
    94081 atcaaagaaa gtcacaagca agaatgtcag cactacgacc cacatttgaa gagaattgat
    94141 gtcccctaca tgttttaatg caactaaaaa tgttggtttc aaacttggtg ctgcggcaac
    94201 aatttcagaa ggcattggaa tcaaacctgt gaccagacct aaaatcgttg tagctgctat
    94261 cccgatgaag atgccacctg gtacacgccg aacaagcaag atagcagtta cgactaatcc
    94321 aaaaatcgtc aaccaagtag aaccaacgtt gagtgatcct aatcctacta atgtagattc
    94381 attcgaaacg atgatcccac cttcgctcag accaaggaaa gcgataaata gaccgatacc
    94441 gccagaaatc gcatatttca aatctgctgg gatcgcatca atgatcattt cccgcagctt
    94501 gaagattgtg atcaaaataa aaatcaaaga agcaacgaat acgccggcta atgctgtttc
    94561 ccatggaatc cccattccta aacaaacaga ataagcaaaa aaagcattga tcccaagagc
    94621 aggtgccgtt ccaattggat aacgggctaa tacccccatt aaaacacagc cgatcgcact
    94681 ggctaatgca gtcgcagtaa acactgctcc ttcatccatt ccagaagcac ctaatacagt
    94741 tggatttaca aataagatat aagccattga gataaatgtt gtaaatcctg ccagtacctc
    94801 acgttttacc gtggtgttca atttttctat ttcgaagtag gaaagtattt tttccttcat
    94861 cttccatccc cctaaatccg aacattataa ataaagtccg ttaaaatttc gatttattaa
    94921 taaaacaacg tgttttatca tatactaaaa caaaacataa gtaaacaaaa aattcggatt
    94981 ttaagcaaaa tccgaacgtt ccatctgatt aaatcccttt atctcaaagt tcatgaacat
    95041 tcactttgga ttacaagaat ttctttattg tgttaataaa gtttcttcat tctagtctca
    95101 aaaatcaata gtgtgatttg attttaccat ttcgtttctg ttcttctttg atgaattctt
    95161 ttgtatcgac aggattcaga ttatttagtc cgccaaaacc tgtatcgacc atttttcccc
    95221 agccttttgt cttctttttt cctgatttga gattctttgc tcgaagcttc tcactatgtt
    95281 ttgctcgccg atacttcaaa taaccttcta atcttcccat tagatccact gtttttcctc
    95341 ctttttattc aatcagacga ctcagctttt cctataacaa aataattgcc ttcagggtca
    95401 gaaaaattga aagtcaagat gccattgtta tctgtgattt ctcctggttc ttccatgttc
    95461 tcgtagatag tttcaaattc atccgtaaaa aatactaaag aaggcggtgg tcctaatacc
    95521 tctggtgaaa acttctgcac aaatactttt gggaatacgc ctaattctaa ttcttttgag
    95581 atgctgagta caatactctt aaattcttct ggcaattcga ttgtttcaga aatttctgca
    95641 ccaatttttt ctacaaagaa tcggcaaatc atctctacgt cattgacata aagcatcaca
    95701 cgtgtttttt gtatcatcat ttgacccttc tttctatttg attttctttc ctgtctataa
    95761 actgattcca ttatatcacg aaagcgcaaa caccttgtgt ttgatactat tcaagaaaaa
    95821 taaagcaata gtttctagga ttgctttcct ccacaaactt tttttacaaa aaaaaaaaac
    95881 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    95941 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    96001 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    96061 ccgctgcttg tgtttcttcc gtcagcattg ttctttgggc ttcacgccag ttgagacagc
    96121 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    96181 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    96241 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    96301 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    96361 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    96421 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    96481 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    96541 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    96601 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    96661 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    96721 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    96781 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    96841 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    96901 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    96961 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    97021 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    97081 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    97141 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    97201 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    97261 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    97321 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    97381 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    97441 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    97501 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    97561 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    97621 ttcagccatt tcatcccacc tttattttgt ttgtaagact agtttacctc tttttgttgc
    97681 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    97741 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    97801 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    97861 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    97921 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    97981 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    98041 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    98101 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    98161 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    98221 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    98281 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    98341 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    98401 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    98461 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    98521 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    98581 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    98641 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    98701 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    98761 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    98821 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    98881 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    98941 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    99001 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    99061 gatcacgttt gtaccgacgt tgacataaca cttcaaagtc tgctgttagg cgaatcgtga
    99121 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    99181 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    99241 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    99301 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    99361 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    99421 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    99481 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    99541 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    99601 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    99661 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    99721 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    99781 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    99841 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    99901 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    99961 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
   100021 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
   100081 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
   100141 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
   100201 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
   100261 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
   100321 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
   100381 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
   100441 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
   100501 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
   100561 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
   100621 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
   100681 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
   100741 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
   100801 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgatgaatc ccatcgaatt
   100861 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
   100921 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
   100981 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
   101041 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
   101101 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
   101161 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
   101221 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
   101281 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
   101341 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
   101401 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
   101461 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
   101521 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
   101581 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
   101641 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
   101701 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
   101761 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
   101821 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
   101881 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
   101941 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
   102001 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt ttttaccctc
   102061 ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat tttttcttca
   102121 atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg atcaactgcg
   102181 aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg tttcatggaa
   102241 actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt gttcaaaaca
   102301 tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca tacgaataaa
   102361 atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc aactactgaa
   102421 aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc caacttctct
   102481 tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta ggagtctact
   102541 gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa atcgattggt
   102601 tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg tcgggcatgg
   102661 gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac tgcacgaatc
   102721 atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct agcagctagt
   102781 tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct gtccgtcaaa
   102841 atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt tgtttcgaat
   102901 aatttttcta acttgccata gatgattcga tctactcggc caccactttc tttcatgaca
   102961 tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa ccgctgtagt
   103021 tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt taaaatcgga
   103081 tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa aaccagattg
   103141 acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt aatctcgatc
   103201 tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat cccatggtta
   103261 cagacaacga ctgatttata aacataattc aagtctcgct tgattacact ggcgatcgtc
   103321 gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc aattacttct
   103381 tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt tgttcggatg
   103441 ttttctttca atggattcat gacttggata tgattcttga ttcttacaat cagtgcagcc
   103501 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
   103561 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
   103621 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
   103681 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
   103741 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
   103801 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
   103861 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
   103921 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
   103981 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
   104041 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
   104101 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
   104161 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
   104221 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
   104281 gcttgctttt ccttttccag cttcaacaaa aaaactttgt tgcgaattgt acggatctcc
   104341 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
   104401 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
   104461 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
   104521 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
   104581 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
   104641 atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg tgaaaaagct
   104701 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt tttcgtttgg
   104761 ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag gttgtgacag
   104821 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca tattttacaa
   104881 aatcgtgcct tattgccgat aggctatctc tggcacactg tttattcaga aaaaggagct
   104941 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
   105001 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
   105061 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
   105121 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
   105181 gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca ccgtctgctt
   105241 tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa cagcttctgg
   105301 ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc ttttggattt
   105361 ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat atctccgctt
   105421 tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc cctcctactg
   105481 acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct gtacctggac
   105541 cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg cccccatatg
   105601 aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct ccaccatgac
   105661 cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc actaacaaaa
   105721 tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat tacaaaaaac
   105781 tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata aactgttttt
   105841 ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg tgtcggcagt
   105901 ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg cgcttcctcc
   105961 aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac gatttggtaa
   106021 agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt tctgatcact
   106081 gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca tatgcatttg
   106141 tttctgtaca tatgaatcat tatctagctc cttagctgct tggattgcaa gcctgatatg
   106201 cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt gcttcaccct
   106261 atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag caagcttgct
   106321 gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt tttgtgcaat
   106381 gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga tgccatttgt
   106441 agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt ctcttaactc
   106501 ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag gagttagcgt
   106561 cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg catccagtgc
   106621 atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt cctctaccaa
   106681 cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga cactcactcc
   106741 ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga tatgaagtaa
   106801 ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa tcatgactcc
   106861 tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga aaacaaatac
   106921 attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg gcaattttgg
   106981 cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga tgactaaact
   107041 gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt ctcctggatg
   107101 tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta agaaaagata
   107161 acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg ctaccccata
   107221 aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat aaggcccagt
   107281 caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg aaccaatcaa
   107341 tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa caaaaaacgg
   107401 catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg ctccatcacc
   107461 tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt gttggactgc
   107521 tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta gttcaaaaaa
   107581 cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca tattataaac
   107641 aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg taccaagaaa
   107701 agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg tttgcatcat
   107761 aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga tttttttgtt
   107821 ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt taatttaggt
   107881 ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc ttttagtgaa
   107941 aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc aggatgcgat
   108001 tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa atcaaaatca
   108061 ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct gccgccgatt
   108121 ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata aacaggataa
   108181 tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg atgaatgact
   108241 tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc aggtccacgt
   108301 aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt tccgaacatc
   108361 ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg tttatcaaaa
   108421 aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc cattttggca
   108481 cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt gtatcgattt
   108541 gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat tgcttcgatg
   108601 actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag gaaatgatag
   108661 atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac tttttcagca
   108721 gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc tttagacatc
   108781 gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg taatccatgt
   108841 gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg atgtccagct
   108901 tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat accgatcaat
   108961 tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat tggccgtttc
   109021 acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat gcggaaacct
   109081 tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg atcaggtacg
   109141 attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata cacagtacta
   109201 atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta accaacactt
   109261 gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt tgcttgatgg
   109321 ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc taaagaatca
   109381 agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg ttcgtccatt
   109441 gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc atcaatgatt
   109501 tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt gtcactagaa
   109561 tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa accgactctc
   109621 gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat accgccaaat
   109681 gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag agcaatgatt
   109741 acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa acgaacacca
   109801 cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc ttctaacaca
   109861 tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc accttggaat
   109921 tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg gctgacaacg
   109981 atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc gatgatttga
   110041 tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg ttctctggcg
   110101 tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg tcaatcgtag
   110161 gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg aaattggata
   110221 acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat cgcttcctgt
   110281 acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt ccaaatctcc
   110341 tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg gatatttata
   110401 agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac gttctgctta
   110461 ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg ccaattttat
   110521 gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc gatcaaatca
   110581 tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat gcctagatct
   110641 tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt cgtgctagtc
   110701 attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc ttcttttgtt
   110761 tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt atcttcgcta
   110821 taaatcatca ctggtgcatt ggctaagcct gcttgttttt gaacagctag tgcatctaat
   110881 tcttcgacaa agactggttt tttatttgaa ccatatgttt caaccatttg aacaactaat
   110941 ttttggcctt tccctaatgg atcatcattg tcgcgaagtg attgccatgc tggtgtagaa
   111001 tgacgacgac cgccaggatt atgtcccatg ttaggcgcac cgccaaaacc agataaacgt
   111061 ccttttgtta cggtagaaga gtttccttcg taatctaatt gcaaggttga accgataaac
   111121 atatcgatgg catattgtcc tgcagcttgt gataatgttc ggttactgcg catcgtgccg
   111181 tctttaccga caaaaaagac atctgggcga gcagcaatat atttttccat accaacttcg
   111241 ccaccaaaac tatggatgct ttcaacccaa cctgattcga tggctggaat catcgttgga
   111301 tgtgggttca atacccagtt cttcgcgatt ttccctttta accctagtga ttcaccataa
   111361 gttggcagta acaattcgat agctgctgta ttgaatccaa taccgtgatt caaagattgt
   111421 acgccgtgtt ctgcgtagat tcctttgatt gccatcattg ccattagaat ttgcaattct
   111481 gtgatgtttt gaggatctcg tgtgaataaa gcttctaatt gataaggttt atctgctttc
   111541 acgacaacgt ctacccagtc accagggata tctacacgtg gtaaagaatc gacaacttcg
   111601 ttgacttgaa cgatcacgat accatctttg aaagctgcag cttcgatgat tgttggtgtt
   111661 tcttccgtat tgaaacctgt gtacaagttg ccgtctttat ctgctttatc tgcagctact
   111721 aaaacaacat ttggaatcaa atcgatgaat aagcgtccat aaagttccaa ataagtatgg
   111781 atatcaccta atttcattgt gccgtcttca atcatttggg cgacacgcaa gctttgtgca
   111841 ccagcataag agaaatcgat cttgcttgcg attccttttt caaaaatatt caaatgttct
   111901 ggtcgtgaga tactagacat gatcaaatgc agatcattca ctttttctgc atctactttt
   111961 tcaagacttt ctgaaagaaa acttgcttgt ttttgattgt cgccttctaa tacaactttg
   112021 tcgccgggag caatcagttt ttccattact tctacgattt tttcagtttc tacatacttg
   112081 ccattgagca agttgctgat tttttccaat cgctgcgctt ttttttcgcg tttagaagcc
   112141 cagttgcggt ttggtttttc cataattagt catctccatt tttgatatag aaacgtggcg
   112201 tcatcaatac catgttggtc tagattgatc gtacggatcc ctttatctac accaaatttt
   112261 gtatgaatca gctttgtcaa agtattgccg gggggaaatt caatcgtcag atccattcct
   112321 aattcttttg ccaagtccat catttggttc cactgcacag ggaaagctag gttttccaac
   112381 aaatctttac gaatctcttc tgcgtcctga gtggctcttc catccgtatt ttttatatac
   112441 aaacatctag catcagatag atggacagac tgcatatacg gcttgaattt cttgaccgta
   112501 tcattcatca agagacagtg agatggcaca gggactttca gcagcttcgc tgtttgcgct
   112561 tggtgccgtt tggcttctgc caacgtaacg gataaacctt cgatactccc agataacgta
   112621 tgttgcatcg gacaattttc atttgacaga taaactggat ggtcaggatc aaatgttttt
   112681 gctacaattt cctcagcttc gcttctcgtc acacctacta ctacgcccat tgcataaccg
   112741 cttggataag cttctttcat taagactgcg cggtgataga ctagttccgc tgcattctca
   112801 aatctcaaag atcgacaagc aacagctgca caaaaagcac caatcgaatg tcctgctgca
   112861 atatcaggct gaataccgtt tttttccatt tcatctaaat aaaatactgc ttttgtcagt
   112921 aatgctagct ggataaaaac cgtatcttga tagttttctt ctttatcaac taaccgatac
   112981 cccgtcacat tttctaaacg ttccatgtac atttcaggga tatccgctaa catccctaac
   113041 ttctgactgc cttgtccagg aaataagaaa cctgtactca tgagcctcgc ctcctcagca
   113101 cttacttttt ccactgctat cttagtcaat ttctgctata ataaaaaatg ccaaaaaaag
   113161 aaaaaaccat aacaaaaagg tatggatggg atggataatt atgaaattgc ttcatctgca
   113221 gtattttaaa aaagtattcg aaacaaaaaa tgttacccaa gcagccaaag aattatttat
   113281 ttctcaacct gccttgagcc gtgcgatcaa acatttggaa aacgaattag gtgtcccttt
   113341 gttttaccat agcggcagaa acattgagac gaccgtttat gcagaagaat tttatccata
   113401 tgcagtcaag acattagaca cattagaaga aggaatcaaa ttattgtctt cggtcaatga
   113461 gaagatcgtt acttccgtca tattgtattt agaggtagcc tctgtttcta ttccgaactt
   113521 ggtccgaatt tttatggaaa agcatcctga tatccaatta acgatcatgc aacatcattt
   113581 accagatgat attaccgatc ctgtactgta catcacttcg gagatgaagc ctggcatgac
   113641 caatattcct atcatgaaag aacctgttta tgtcgccatt cctaagaaac atcctcttgc
   113701 taaaaaagaa catctgcaat tagaagatat ccaacgcacc cccatcttga tgctgtcaaa
   113761 gagcaacgcc ttccgtcata cactggatgc agcacttgaa gcgaaaagta tcgaattgac
   113821 gatcagttcg acgacagatg atcctgcgac attacgttct attgtcaagc aaggattagc
   113881 tgttagcttt ttcccaaaag tttcttggtc ttacgataaa aatgatcctt tcgtcttgcg
   113941 ggaaatcaaa gatttgccct tgacacgaac aatttattta tcttctagct tcacagaaga
   114001 tcatcctttg atcaaaatga ttgcaaaaac gatgcgggaa ttttatttag gaaaataaaa
   114061 aaaaaagagc tgggacaaaa ttcttgtcgc agctcttttt tcgaacaaac ggtgttccag
   114121 aagtaatttc ttagaaaata agccgaaatt tcccaaaaat ttgagaagca attttcgtaa
   114181 attccttctt atttcttgaa gctaaacatt tctgtcacaa cctcttctct attgtcctag
   114241 acattcattg cgttgattta aaacttccat caatcaaatc tgctagttca tctagctttt
   114301 ctattttacg tagatcaata gagatccaat gttctttatt catgtgatag gctggaaaat
   114361 acccctcttt tcctcgcaaa attccgccaa gttcaggatc gaccttcaaa tcaagaatat
   114421 tgatgatcct atggtcactt gcatcatcat agattttttc ttctggaaca gacatcagga
   114481 ccccaaacca ttttttgctt ttttgatgtc tgaatacgca ataatcagga aattttttaa
   114541 aaatatattc tggagacaaa ttgtatgttt cattgatgtg atcgattagt tcttttttcg
   114601 ttagcatctg cttccatctc tttcttattg attcgcttta ttcaaagata ccacgtaaga
   114661 atagaaaaat gaatacaagt agttgctaat caaatacttc gatatttttc ttttttatca
   114721 actcttaaat gttcaatccg cctgtgttgg tcttgctacc atctactatt aaaatgttta
   114781 ttattgtttg cccacctatt ttttgatttt agtggtatca tttttcaagt tcatgatgaa
   114841 attcttatca tcagtaaatg ctccagaaaa ataaacaatg attgaaaaat cagttgaaac
   114901 ttgaccaccg tttattttct ccgtattctt agaatagaag ggagtctgat tgatgtattc
   114961 actaatgaaa aaaatcatta ccgaaaaaga tattcgacgt catgtttctt tagtagaaca
   115021 attgctgaat catacaaaga taaccgtaaa tgaattagct gaaatcatag ggacaaccga
   115081 acgaacgatt ttttctgacc ttcaatctat tcgctctcag ctgcccgaag gctgggacat
   115141 catcagcgat caagcaggaa tcagtttgca aaaccagcaa aatttattaa caaatgacct
   115201 ttgggagatt tttttcaaac aatcagtcag tgtcgaactg ctgaaaaatc tgctttttac
   115261 aaaaaaagtt gctgtccctg attttctagc cgaccatggg ctttcttatg ggacattgaa
   115321 aagacatgtg actaaaatca atcagcgttt agcaagttac gacttgcaga tcgatttgac
   115381 gaaatataca gcttgtattc ttggaaaaga gcgtgcgatt cgtacttttt atcatcgatt
   115441 gctgattcct ttcactcata acaactattt tttcgaggat tattcgatcc atgaatccca
   115501 ttattttcaa tttttaagaa acctcagtca aactgaacta gcggttgaaa cagaagagat
   115561 tttcggaaca tgttggttct ttatcaatac gatccgtata aaagcgaatt gccgattaga
   115621 ttcttctatc cataccaaca gcacactctc ctccctgtat gactctgcat tgaaaaaatt
   115681 gtatttaacg gaaggtattt atcttaaaga cactgagctt tcttttgctt ctttctgctt
   115741 tctggaaagt tggaattaca acaataacta tggacaagaa accgctcgct gcctgcatca
   115801 ttctccattt ttagaggtcc tcgaaacgtt tgtagaggaa ctagcttcag agctgtctct
   115861 tgatcaacta aaaaaaacat ctctgactga taacttggct ctcctcatat taaaatatca
   115921 tgaatcgccg atattgattg aagcattgga ccgtcaatac catcgttttt tagaaacata
   115981 tgatcagcaa tatgcacact tgtatcaaca gaaagagaat ttactgaacg atctaaaaaa
   116041 agaaatagaa atcaatgaac caaattactt tctccaactc ttgtctctac tgatccaaca
   116101 aacgattttt tctatcaaac cgaatttgtt caatgtctat tttattttcc aaggagaacc
   116161 ttcatggaag gcgttcttgc agcaggaatt aaaagattac ttaggaaaac gtgtctgctt
   116221 cttacctatc gaactaaccg atctttccac tatttctttt gaaaaaacag atatcttgat
   116281 ttccaatttc cctctagatt ctctagatat ccctattgta tacatttctt ctattccaac
   116341 gaaaaatgag ctcaatcgtt tgactgaact cactttcaaa acttttttat agtaacggct
   116401 agcgactgta ttctctagct gttttttctt ttttgcgaaa cagtttgttc atgatccctt
   116461 tttctatttc tacaactaag aatagaagaa tcacatttgc tccaatcaat aactgttgtg
   116521 tcatcgttaa acttactgta ccgatcagct gctggccgac tggtagaaaa ataaccatcc
   116581 cttgcaataa agcaaggata cctaatgaaa gaaaaagcgc tttgttttgc aaaagacctt
   116641 ggttcaatga cggcttggac aactctctgc aattgatcat gtaaacagct tgagctaaga
   116701 cgatattttg cagaagaatg gtttgctgta agctttgccc ttcaaactgc atagccaata
   116761 aataggcagg aaccatgatc agtagggaga catagatgat ccgaaacaaa tgataaccag
   116821 ataggattcc ttgctttgga tctcttggtg ggcgcttcat gatttctgga tctggcgact
   116881 cgaaccctag tgcataagat aaagtgattg tcgttaccat attgacccat aaaatctgta
   116941 ctggggacaa aggtagcggg cgattcagca taagtgccca aatcaagatc aatccttgag
   117001 ctaatgcagt tggcaagaag aaattgatgg ttttttgcaa attatccaaa atccgccggc
   117061 cctcttttac ggcttttgca atcgtatgga aattatcatc tcctaaaacc atatcagctg
   117121 cctgtttgct tacttcacta cctttgattc ccatagcaat tcctacatcg gatcttttca
   117181 aagcaggtgc atcatttacg ccgtctccgg tcattccgac gatttctcca tttttctgca
   117241 aagctttaac aattcgcagt ttatgttctg gtgtcgttcg agcaaagaca tcgactattg
   117301 gcacttgctg aatcaactct tcatcagaca taagatccaa atcgatccct tctaaaactt
   117361 tggcagtatg ttttaagcca atttgttccg caatcgcttt tgctgtgtct ttgtgatccc
   117421 ctgtaatcat tttcactgag atccctgctt gttggcattc ctttacagct ttgactgcac
   117481 tttcttttgg cggatcgatc aatccggcga tccctgcaaa agttaattgg gttaaagtct
   117541 catgcgtgag ttcctgtttc gaatctactt ttttataagc aaatcctaaa acacgctgac
   117601 cttttctcgc aaattctgca gctgtctgac tccatgcttc ttgttctgca gaagaaagag
   117661 ttgatttagc aaataatact tctggtgcac ctttgacgta aatcaccgct cctttttcct
   117721 ccgcatgcat cgttgccata tatttgtatt cagaactgaa cggaatcttt gcttctattt
   117781 ttttcaaagg tagattggct gtttctgtgt gtcgaatcag cgcaacttct gtcggattgc
   117841 cacttaaatt ttctgttttc tgttcttctt ttgtttttaa ttcctgacag tttttcataa
   117901 tggacaacac gcaggcttct tcttttgcag ctacatccac aactgtcatt tcattttttg
   117961 tcaatgttcc tgtcttatct gaacagatca ctgtcataga acctaatgtt tctaccgaag
   118021 gaagtccttt gatgatcgcc ttttcttttg ccatttcatg tactccaacg gatagaatca
   118081 tggtcaaaac agctggcaat ccttcgggta ccattgacac caccaaagca atcgtagccg
   118141 aaagaaggat atgccaatcc ataccatatc gaaatgtcgt aaaaataact aagaataggc
   118201 tcaaacaaag aatgccttga aaaatttgtt tgtttaatcg gttgattttt ttaatcagag
   118261 gcgtcgtttg ttgttcgacc gattgcaatg cttgattgat tttaccgatt tctgtcgtgt
   118321 ttcctgtttc tacaacgaca ccgactgcag aaccagattg tacaagcgtt cctgaaaaag
   118381 ccatattttt ctggtcgccg atcgattctt cttctgtcaa aacggcatga cttttttcag
   118441 atgcttctga ttctcccgtc aaaatcgatt cttccactaa taaatcatgt gcttcgatta
   118501 atcggatatc tgctggaacg acatctccgg cacgtaagac aatgacatct ccttttacca
   118561 gttctttcgc agggattttt tcttgcatcc cgtttgatag tactatcgct tcttgtccca
   118621 tcagctgctt caaaccattc aatgattctt ccgcttttct ttcttgccag taactaacga
   118681 gtccattgac gatcactacg aataaaataa tacttccttc aatatattca ctagaagcaa
   118741 atttcaaaaa agaggcaatg atcaacacga tcatcagcag atcagtaaaa tgctttgcta
   118801 tttttttcca tcgttttgtc tgctgccttg cttttatttc attatatcct tgatcagtca
   118861 ggcgtttctg tcgttcttct tgcgacaagc cttctgttga tgtttgatag tttttcaata
   118921 catcttctac cgtcaatctg taccagttca tcctatcccc tcctgtttaa ttgatactgt
   118981 tattatacgc agggaagttt tttcaggcgt atcgattatt tcaggggggt ctgaaataat
   119041 tcgttttgca aaatgtatct gggcctaact gatatttcta ttgcttattc ttttatatac
   119101 aaaatttaag aatacaaacc agataaccaa taaaaaagga ataaagcgtg tcgtgctttc
   119161 gaataacaag ctgaaagcaa ttgaagtaaa aaacaccaac aaagcaagat ctttatatct
   119221 ttgtgtagtg ttccgtttct tttctttaat aaattgaaca tgtgcacaca agatcgaaga
   119281 ccacacaaat agaaaacaac tcgttgtcat gcctgccaaa agctgaaaaa acaatcgact
   119341 atcagctaca aaaaaatgta gacaaagacc ggcaaaaaat aacattcctg taattaaaat
   119401 accgtgtaaa ggtacgcctt tcttagaaag cgcacaaaac caatggggca aacttttttc
   119461 ttttgctgtt tgatataaaa tcctgctagt actgtagact gcactatttg ctgaggacaa
   119521 agaagcaacc aaaatcatta gattgacaat tgctgctccg ccttggcaat ggatcacttg
   119581 cagcatagtc actaaaggac tttcttttaa atctaaacaa tgccatggaa caacaaataa
   119641 aatcgacaaa atcgttccta tatagaaaaa gagaatacgc caaggcagac agttgattgc
   119701 ttttttcaaa ttcttttgcg gatcacttgt ctcgccaacg gttaagccga tcatttcaat
   119761 tccagcaaaa ctgaataaaa ccataggaaa tgagactacc attccagcaa agccaaacgg
   119821 tagtaattca tcgatctgtc caaaattttc tttgattccg atagactggg tatgaaaatc
   119881 tgagacactc aatcctatac ccaataagat aaaaaggaaa atccccaaga tcttgatgat
   119941 tgagaaaaaa gattccaatt caccaaacca cttgactgca acaaggttga ctgccattaa
   120001 gatcattagt gcgctacctc cgcttatcaa agctggtaca tgtacaaacc agaaatggat
   120061 atacaatcct attgctgtta attccgcaag tccagctcca agccagcaaa gccaataagt
   120121 ccaattgaca aaaaatgccc actttttgcc taaataatag tcaacgaaat cactgataga
   120181 gttaaatgta ctatttgcta aaaataaatc acccatggcc cgcatcaaac cataaatagc
   120241 caaaccgcat atcaaataaa cgagaataac agctggccct gctgatgcaa ttgcctttgc
   120301 tgaacctaaa aataatcctg ttccaattgc gccacctaat gcgattaact ggatatttcg
   120361 attagttaga gtccgtttca ttgccggttt ttccatcaag ttcacctttt tctttttcaa
   120421 gcagcatggc gacttcctgt tcccaagaag gtttctttat tttttcaata cagagtggta
   120481 ctacaaacaa aatgacactg atggctgtga ctgcaattag attgatccat gttccagctt
   120541 tcatcgtcag tccgacagaa aatccgattg ccgcaaataa aacaataacg acagtccaaa
   120601 ctccaagatt gctctttttc tctttttttc caattctaaa tggtcgattc aactttgcat
   120661 gtgtataacg caatctcaaa actgcgatcc ccatgatgac atagacgata cagtagataa
   120721 cagtagttga atttacgagc atcaaaaatg cttgattgac gccaggaatc agcaaataaa
   120781 aaagtgcaaa gattgagata atgacagact gagtcaaaat aacggatttg gatacgtcaa
   120841 attgattcgt cttccaaaaa ttgaattttg gtggatacgc accttttcta gcactttctg
   120901 tcactgtctt tgctggtcct gaggcccaag cagataattg gactgctaca ccaatgaaga
   120961 caagtaaact aaacagattc acaataagat gtggcaaacc aagaatttgg caataaatcg
   121021 aaatagattg cgcgatatta ttcaattcca tttgtccttt tggtacgaca tttgctacaa
   121081 ctaaagcatt caaaatattg acgaaaaata taaaaattaa cgcggcaaat actccgcgaa
   121141 tatacgtttt aactggattt tccaatcgag tgatatacac agaggacatt tcgataccag
   121201 taaaaataaa catgatcggc gcaaaataaa caaatgagga tgcagtcgta gtatctggta
   121261 ttaatttgtc ccatgaaaaa ctgcctaatg ttccggttgg tacgatccca actttgatcc
   121321 acgcagcaaa ccctaataag agcatcatcg tcaaaggcac gtacaatcct aaccaaacac
   121381 cgacttttcc gccgattttt gccatatcaa atttcaaatt caaaagagtg atgatccaat
   121441 aaacgactaa aatgacaact aatgtaaatt tgctgttcaa accaagcggc acattatcga
   121501 taatattacc aaacaacgga gcgagtgctg aagcgaccat caccatccca ggaaacattt
   121561 ggacccataa cagccatgag acaacgaacc cccatttttt tcctagagca ttcgataccc
   121621 aaagttctgg accacctttt tggggaaaca ttccagcaaa ttcaccagag atcaatgaga
   121681 ttggaaaagc gtacaataat actgcaacca gcatgtaaaa aatcatcgtc cagctcgttg
   121741 ctgctacatc tggaatattt cgtacacttg ctacaagggc gcaggtcatt ccgataaagg
   121801 tcatggtcgt gatttgcttt gatgaaccag tatctttcat ctttattcct tctttcaata
   121861 gcgacatatg tttttgtttt cttttatttt tgttcaagaa cagaaatgac aaggtttcat
   121921 cgattcagta caaaacccag tatcaccgaa acatccattg aacgatctta gtgaactggg
   121981 tttgatacat gaaacgaacg atccaactta tagaacgttt tataaaaaag aatatcttgg
   122041 cgaggaatat atgaaaaaca gggggaaata caattgtttt gatgaagcaa ataattgtct
   122101 gttctccata tgtctcttgt tattctttca cacaaaaatc agttctattg gatgatttcg
   122161 tttagtttct tttccattgc tttggcgatt ttttttgtat aaaaattgaa aattcgatca
   122221 tcattcaaat aaggagtcat gatagccgca cgtagcagag tgattttctg ttcttttttc
   122281 cattcttctt tcgttagacc cattctttca acaaaacgaa tcggagaatc accgtaatct
   122341 tcttgtgtaa atgtagtatg agaagtaata aaccgttcac cataaacatc gccatccata
   122401 taagaagacc gatcgaacat tttttcattt aattcattga tagcgttcaa atctgtacag
   122461 ccttgttctt tgaataccca attgaccata ttaaaatcag gatgattcaa tggatagact
   122521 tcgattgttt ttcctttaac agtaaaagtc agatgatcga gaaattctct gaatctttga
   122581 gctgcctcga ttgaagcccc aatcaattga ccatatccgg tcacattcaa tggcaataca
   122641 cgatgtgctg tccagactgc ggcggcggtt gctccagctt ttgatccttc caaaatataa
   122701 gctcctaaca tatctggagc ctttactgat ttttcaaaca catatggcgc gaaataagaa
   122761 atgatatttc tcatattttt atgtttgatt acgattcctc cagcagcata agggacatag
   122821 cccatcttat gaggatctat cgtgacagaa tccgcttctg aaatagctct gaacccttca
   122881 tatacctctt tgtcaatcgt tacgcagtgg tggaaaacat gatgttcttc aaagaattca
   122941 gctaaggaag catacggcac aaattctcct gcttcgttta gaaacagtga acgcgcatag
   123001 ccgccatatg cggcatcaac atgtaaatag aaatagatcc cttcatcttt taacctttct
   123061 cttaattgga cgattttatc tacactgtct acttgacctt cttctgtcgt tcctacgaca
   123121 gcaaccacac ctagaattgg gattttttgt ccagctaatt cacgaattgt tttttccaaa
   123181 gcattaatat ccattcgata atcctcttga actgggatag caaccatctg atctaagccg
   123241 actccgcaaa tatctaacgc cttcatccaa gaatagtgtt ttgtttgagg gaccagccat
   123301 ttccctaatc tttggatatt ttttccgcta cgggaagaag ctgctttgac ctcatccatt
   123361 tcttcgtccg taaagctttc ggtcatttcc aaaatttctt caacagataa attcaaaagt
   123421 tcccactcag acattttttt cactttttca ggcagcactt ccttgacagc taaaggaatc
   123481 gatttgatgc aacgggcgta ccataatcct tcaagattag caatagaacc atctgctgca
   123541 atgtgtcccc atccgtctgt catattgaat aatgaagcaa aatcctgtcc tacttctgct
   123601 tccatttgcg aagttgccat agaagattcc aatgcaacat tatttgggtt ccacagcatc
   123661 gcatagttgt aagctaataa agcaggcatc aatgtttcag cattcatttg tccccagtaa
   123721 cggcctgctg aatgccatgg gatcgatcct gcgcgtaatc gctgactgac ttcatccaag
   123781 acctctatca tatggtcgcg ggtggctaga taatctggag tgagcttatc tccttcgcta
   123841 attgcaggca tatctgaagg aatataattt tctctccatc caagatgttc atctaccatc
   123901 ttgttcaaca acattttata aactggtcca ttttcagctt tgtcgcctat aaagacggcc
   123961 ttgatatcca tatctttcat ttttcttccc tccatatttt gttggtcaat gtcttgcaga
   124021 tacatgtgtt tatctgtaac acctcttcac tatagcgcca aaaatgagaa attttttttt
   124081 ataacatcaa atccacgtag atttttacaa acaaaaataa ataaagtcgg atttttctga
   124141 taattcaacg caaaaaagcg aacaattttt caataaatca gtcttctaaa atagataacc
   124201 taaaaaaagc gaacaaacaa ataaaatgac tgtccttc
//
LOCUS       DARBDN010000002        89654 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000002 DARBDN010000000
VERSION     DARBDN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 89654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.002"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(553..2166)
                     /locus_tag="SCH06_000107"
     CDS             complement(553..2166)
                     /locus_tag="SCH06_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEG1076718.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="SCH06_000108"
     CDS             complement(2307..3215)
                     /locus_tag="SCH06_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1076719.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3398..4522
                     /locus_tag="SCH06_000109"
     CDS             3398..4522
                     /locus_tag="SCH06_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEG1076720.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4749..5666
                     /locus_tag="SCH06_000110"
     CDS             4749..5666
                     /locus_tag="SCH06_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1076721.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5659..6492
                     /locus_tag="SCH06_000111"
     CDS             5659..6492
                     /locus_tag="SCH06_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1076722.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6575..7693
                     /locus_tag="SCH06_000112"
     CDS             6575..7693
                     /locus_tag="SCH06_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEG1076723.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7687..9585
                     /locus_tag="SCH06_000113"
     CDS             7687..9585
                     /locus_tag="SCH06_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HEG1076724.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9579..10802
                     /locus_tag="SCH06_000114"
     CDS             9579..10802
                     /locus_tag="SCH06_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEG1076725.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10888..12822)
                     /locus_tag="SCH06_000115"
     CDS             complement(10888..12822)
                     /locus_tag="SCH06_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEG1076726.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13048..13704
                     /locus_tag="SCH06_000116"
     CDS             13048..13704
                     /locus_tag="SCH06_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEG1076727.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13778..14131)
                     /locus_tag="SCH06_000117"
     CDS             complement(13778..14131)
                     /locus_tag="SCH06_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEG1076728.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14323..15252
                     /locus_tag="SCH06_000118"
     CDS             14323..15252
                     /locus_tag="SCH06_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEG1076729.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15263..16099
                     /locus_tag="SCH06_000119"
     CDS             15263..16099
                     /locus_tag="SCH06_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEG1076730.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16347..17123
                     /locus_tag="SCH06_000120"
     CDS             16347..17123
                     /locus_tag="SCH06_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1076731.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17299..18042
                     /locus_tag="SCH06_000121"
     CDS             17299..18042
                     /locus_tag="SCH06_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076732.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18035..19615
                     /locus_tag="SCH06_000122"
     CDS             18035..19615
                     /locus_tag="SCH06_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEG1076733.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19866..20345)
                     /locus_tag="SCH06_000123"
     CDS             complement(19866..20345)
                     /locus_tag="SCH06_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEG1076734.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20361..21113)
                     /locus_tag="SCH06_000124"
     CDS             complement(20361..21113)
                     /locus_tag="SCH06_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEG1076735.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21230..21300
                     /locus_tag="SCH06_000125"
     tRNA            21230..21300
                     /locus_tag="SCH06_000125"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21262..21264,aa:Gly,seq:ccc)
     gene            21661..22386
                     /locus_tag="SCH06_000126"
     CDS             21661..22386
                     /locus_tag="SCH06_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEG1076736.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22641..22907
                     /locus_tag="SCH06_000127"
     CDS             22641..22907
                     /locus_tag="SCH06_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEG1076737.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22904..23335
                     /gene="ruvX"
                     /locus_tag="SCH06_000128"
     CDS             22904..23335
                     /gene="ruvX"
                     /locus_tag="SCH06_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEG1076738.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23360..23665
                     /locus_tag="SCH06_000129"
     CDS             23360..23665
                     /locus_tag="SCH06_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEG1076739.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23746..24891)
                     /locus_tag="SCH06_000130"
     CDS             complement(23746..24891)
                     /locus_tag="SCH06_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1076740.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24952..25599)
                     /locus_tag="SCH06_000131"
     CDS             complement(24952..25599)
                     /locus_tag="SCH06_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1076741.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25793..26086
                     /locus_tag="SCH06_000132"
     CDS             25793..26086
                     /locus_tag="SCH06_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076742.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26130..26441
                     /locus_tag="SCH06_000133"
     CDS             26130..26441
                     /locus_tag="SCH06_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076743.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26438..27062
                     /locus_tag="SCH06_000134"
                     /pseudo
     CDS             26438..27062
                     /locus_tag="SCH06_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27203..27361
                     /locus_tag="SCH06_000135"
     CDS             27203..27361
                     /locus_tag="SCH06_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076744.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27362..27724
                     /locus_tag="SCH06_000136"
     CDS             27362..27724
                     /locus_tag="SCH06_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076745.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27761..28609
                     /locus_tag="SCH06_000137"
     CDS             27761..28609
                     /locus_tag="SCH06_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEG1076746.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28599..30074
                     /locus_tag="SCH06_000138"
     CDS             28599..30074
                     /locus_tag="SCH06_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEG1076747.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30340..30747
                     /locus_tag="SCH06_000139"
     CDS             30340..30747
                     /locus_tag="SCH06_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HEG1076748.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30750..30965
                     /locus_tag="SCH06_000140"
     CDS             30750..30965
                     /locus_tag="SCH06_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076749.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30969..31349
                     /locus_tag="SCH06_000141"
     CDS             30969..31349
                     /locus_tag="SCH06_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEG1076750.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31483..31638
                     /locus_tag="SCH06_000142"
     CDS             31483..31638
                     /locus_tag="SCH06_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEG1076751.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31707..32180
                     /locus_tag="SCH06_000143"
     CDS             31707..32180
                     /locus_tag="SCH06_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEG1076752.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32177..33871
                     /locus_tag="SCH06_000144"
     CDS             32177..33871
                     /locus_tag="SCH06_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEG1076753.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33837..34022
                     /locus_tag="SCH06_000145"
     CDS             33837..34022
                     /locus_tag="SCH06_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076754.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34026..35201
                     /locus_tag="SCH06_000146"
     CDS             34026..35201
                     /locus_tag="SCH06_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEG1076755.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35194..36717
                     /locus_tag="SCH06_000147"
     CDS             35194..36717
                     /locus_tag="SCH06_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEG1076756.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36773..37057
                     /locus_tag="SCH06_000148"
     CDS             36773..37057
                     /locus_tag="SCH06_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEG1076757.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37044..37379
                     /locus_tag="SCH06_000149"
     CDS             37044..37379
                     /locus_tag="SCH06_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEG1076758.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37674..38300
                     /locus_tag="SCH06_000150"
     CDS             37674..38300
                     /locus_tag="SCH06_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076759.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39042..39879
                     /locus_tag="SCH06_000151"
                     /pseudo
     CDS             39042..39879
                     /locus_tag="SCH06_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
     gene            39944..40378
                     /locus_tag="SCH06_000152"
     CDS             39944..40378
                     /locus_tag="SCH06_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1076760.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40446..41768)
                     /locus_tag="SCH06_000153"
     CDS             complement(40446..41768)
                     /locus_tag="SCH06_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEG1076761.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41922..43562)
                     /locus_tag="SCH06_000154"
     CDS             complement(41922..43562)
                     /locus_tag="SCH06_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HEG1076762.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43892..44362
                     /locus_tag="SCH06_000155"
     CDS             43892..44362
                     /locus_tag="SCH06_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HEG1076763.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44991..46094
                     /locus_tag="SCH06_000156"
     CDS             44991..46094
                     /locus_tag="SCH06_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEG1076764.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46378..47058
                     /locus_tag="SCH06_000157"
     CDS             46378..47058
                     /locus_tag="SCH06_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEG1076765.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47148..48182
                     /locus_tag="SCH06_000158"
     CDS             47148..48182
                     /locus_tag="SCH06_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEG1076766.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48196..48531
                     /locus_tag="SCH06_000159"
     CDS             48196..48531
                     /locus_tag="SCH06_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076767.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48515..50995
                     /locus_tag="SCH06_000160"
     CDS             48515..50995
                     /locus_tag="SCH06_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076768.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            51051..52610
                     /locus_tag="SCH06_000161"
     CDS             51051..52610
                     /locus_tag="SCH06_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076769.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52607..53971
                     /locus_tag="SCH06_000162"
     CDS             52607..53971
                     /locus_tag="SCH06_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEG1076770.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54142..55212
                     /locus_tag="SCH06_000163"
     CDS             54142..55212
                     /locus_tag="SCH06_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076771.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55227..55895
                     /locus_tag="SCH06_000164"
     CDS             55227..55895
                     /locus_tag="SCH06_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076772.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55915..56493
                     /locus_tag="SCH06_000165"
     CDS             55915..56493
                     /locus_tag="SCH06_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1076773.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56896..57807
                     /locus_tag="SCH06_000166"
     CDS             56896..57807
                     /locus_tag="SCH06_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEG1076774.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58063..58980)
                     /locus_tag="SCH06_000167"
     CDS             complement(58063..58980)
                     /locus_tag="SCH06_000167"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEG1076775.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59182..59619
                     /gene="zapA"
                     /locus_tag="SCH06_000168"
     CDS             59182..59619
                     /gene="zapA"
                     /locus_tag="SCH06_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEG1076776.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59677..60224
                     /locus_tag="SCH06_000169"
                     /pseudo
     CDS             59677..60224
                     /locus_tag="SCH06_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            60339..62699
                     /locus_tag="SCH06_000170"
     CDS             60339..62699
                     /locus_tag="SCH06_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEG1076777.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62786..63100
                     /gene="trxA"
                     /locus_tag="SCH06_000171"
     CDS             62786..63100
                     /gene="trxA"
                     /locus_tag="SCH06_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEG1076778.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63282..65060
                     /gene="uvrC"
                     /locus_tag="SCH06_000172"
     CDS             63282..65060
                     /gene="uvrC"
                     /locus_tag="SCH06_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEG1076779.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIERLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65205..66104
                     /locus_tag="SCH06_000173"
     CDS             65205..66104
                     /locus_tag="SCH06_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076780.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66097..67359
                     /locus_tag="SCH06_000174"
     CDS             66097..67359
                     /locus_tag="SCH06_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076781.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67522..69420
                     /locus_tag="SCH06_000175"
     CDS             67522..69420
                     /locus_tag="SCH06_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HEG1076782.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69719..70438)
                     /locus_tag="SCH06_000176"
     CDS             complement(69719..70438)
                     /locus_tag="SCH06_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEG1076783.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70775..71107
                     /locus_tag="SCH06_000177"
     CDS             70775..71107
                     /locus_tag="SCH06_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076784.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71094..73097
                     /locus_tag="SCH06_000178"
     CDS             71094..73097
                     /locus_tag="SCH06_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEG1076785.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73116..73586
                     /locus_tag="SCH06_000179"
     CDS             73116..73586
                     /locus_tag="SCH06_000179"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEG1076786.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73607..74191
                     /locus_tag="SCH06_000180"
     CDS             73607..74191
                     /locus_tag="SCH06_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEG1076787.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74206..75192
                     /locus_tag="SCH06_000181"
     CDS             74206..75192
                     /locus_tag="SCH06_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEG1076788.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75182..75493
                     /locus_tag="SCH06_000182"
     CDS             75182..75493
                     /locus_tag="SCH06_000182"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEG1076789.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75515..77296
                     /locus_tag="SCH06_000183"
     CDS             75515..77296
                     /locus_tag="SCH06_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEG1076790.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77289..78665
                     /locus_tag="SCH06_000184"
     CDS             77289..78665
                     /locus_tag="SCH06_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEG1076791.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78672..79307
                     /locus_tag="SCH06_000185"
     CDS             78672..79307
                     /locus_tag="SCH06_000185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEG1076792.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79337..80692
                     /locus_tag="SCH06_000186"
     CDS             79337..80692
                     /locus_tag="SCH06_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HEG1076793.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80884..82278)
                     /locus_tag="SCH06_000187"
     CDS             complement(80884..82278)
                     /locus_tag="SCH06_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEG1076794.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82370..83341
                     /locus_tag="SCH06_000188"
     CDS             82370..83341
                     /locus_tag="SCH06_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HEG1076795.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83338..84120
                     /locus_tag="SCH06_000189"
     CDS             83338..84120
                     /locus_tag="SCH06_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HEG1076796.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(84289..84660)
                     /locus_tag="SCH06_000190"
     CDS             complement(84289..84660)
                     /locus_tag="SCH06_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1076797.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84794..85237
                     /locus_tag="SCH06_000191"
     CDS             84794..85237
                     /locus_tag="SCH06_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEG1076798.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85280..86089)
                     /gene="yidA"
                     /locus_tag="SCH06_000192"
     CDS             complement(85280..86089)
                     /gene="yidA"
                     /locus_tag="SCH06_000192"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEG1076799.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86108..87475)
                     /locus_tag="SCH06_000193"
     CDS             complement(86108..87475)
                     /locus_tag="SCH06_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEG1076800.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87459..88289)
                     /locus_tag="SCH06_000194"
     CDS             complement(87459..88289)
                     /locus_tag="SCH06_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEG1076801.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88452..88889
                     /locus_tag="SCH06_000195"
     CDS             88452..88889
                     /locus_tag="SCH06_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEG1076802.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88965..89585
                     /locus_tag="SCH06_000196"
     CDS             88965..89585
                     /locus_tag="SCH06_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEG1076803.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
BASE COUNT        29552 a        15170 c        18472 g        26460 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 aatatttttt tatataaata tttgtgttac taattccgtt aatatacata agtgaaagcg
     3361 ttttatataa gaacttgaaa agaaagaagg gatagacatg aaaaaaagat acaaattggt
     3421 gatagctttg ctaaacatta ccctattatt cagcttaagt gcatgtggaa aaactaacga
     3481 agaagtaaca gcaaacatcg cagatccaat gataaaaaaa gccactacat tagaagtata
     3541 tgtcgcaaac ggcaaactga caaactatgt tgaaaatgct gcaaaaatct ataaccgcaa
     3601 aactggagca aatattgact taaaaattgt gaatgtagct tcgggaacag caacagtaca
     3661 aatgatcacc ccaaaattgg taacacacga agatatgccg gatattatct ccatggcaga
     3721 cacttcagca gcaggtgtgc tggaaaaatt tcaagatgct ttttatagtg ctgatgaata
     3781 tggattttat gacaaatatg gcgatcagtt ttatgatcaa aaattgaata ttttgcgtca
     3841 acaaacgagt aatgaaacga ttattccttg ggctagtgat tttaccccag cactttgtta
     3901 ttatcaacca aaaaaatttg ctgaaatagg tgtagatttt gaagaaatca gttcttggga
     3961 agaatatatc caggtggcaa aagcattaaa agaaaaaact ggtagttttg gaattgcctt
     4021 gccagaatct ggggaccaag aattgtttat caacatgcta gcccagcaga atcaatcttt
     4081 gcttgatgaa gaaggaaata tccgtctgaa tactaaagaa gcgaaacatg ctgcaaagtt
     4141 aatcaaagaa atgatcgact cagatattgt acatttctac ggtgcacaag atgctgagaa
     4201 agcatttcaa gaatctgcaa tgtttgttgc tggcggctgg tatgctacga atatgtcttt
     4261 gaattttcct gatgcatctg acaaatggcg catggctcca ctgattcctt tttcaaaaga
     4321 aaatccagga aaaggtgcag tatcaggagg atcaagtttt tatgtcccta aagatgccaa
     4381 aaatccacaa gtggcacaac aatttcttac atttatgctg acagatgaag aatgcttagc
     4441 caacgcactg gagctgggcg tggctacatc taactcattg gcctatcaaa cagaagcagc
     4501 tgagaaaaag tttgactact aaggaggaca aaaatactat gaactattga ataaaatcaa
     4561 tgaaaataca tcaaatactg ttttaccagc cacttattca gatgctacgt cttatttgac
     4621 taccgctgca tataactatt ggcaaacagg tgattttgaa aattcatatc taaaagaagc
     4681 agaaaatttt gctcataagt acggcgtaaa attaactggt gattaaaaaa tattaggagg
     4741 acttaacgat gatgcaatct tcgttaccaa gcaagacaat aaagaacagc aagaaaaaag
     4801 caacagatac gtctcataaa aaaagtgctt atggattggt cacacctttt gttattttct
     4861 ttattgtgac gattttgatt cccatcatta tctcgtttgc ttttagtttt atgaaaattg
     4921 gctactcatt tgaatttgtt ggatttgaca attatctagc tatcttccga gatccattgt
     4981 ttattaaatc ttacacgaat gttttgatta tcatggcagg atcaattcca ataacgatgc
     5041 tattagctat ttactttgct gttttattga attcagcaca gttaaaagga aaaggatttt
     5101 ttagaactgt ctattatatt ccaaccatta catcaacggt ggctgtagct tccgtattca
     5161 tgactttttt caatccgact gggttattca atggattttt gaatgcgcta ggaattaacg
     5221 gtgtacagtg gttaacaaat cctttttgga tacgaatatc aatgatcatc acgatgattt
     5281 ggcttagtgt aggatataac actattttat ttttagctgg tcttcaaggg atttctaaag
     5341 agatatacga aagtgctgaa atagatggag catcgaaatt tcggcaattc tttttattaa
     5401 cgatccccat gctaaagcca atcattttaa tggccacagt tttagccact atcaatggct
     5461 tgggtaattt caatatccca aatatattct ttgggacttc caatggacca gaaaattcag
     5521 ctttggtcgt aggagtcaat ttatataaaa caagttttga aatggttgat tttggaaaag
     5581 cctctgctat tgcctggacg atggtgtttg tatctgttat attatcggct attcaattta
     5641 aattcggagg tgataaaaat gactaaacaa aagatacaaa gcagaatttt tacgtacgtc
     5701 attattgtgt ttggtgcctt aatatttttg atgccatatt tatatatgat tgtagcttca
     5761 acgcaaagta atcaagaaat tttaagtggc ggaatcaatt tcaagtttgg ggatatgcta
     5821 ttaaaaaact ggcaagccat catggcgaga tataattatc ccttgattat ttggaattcg
     5881 attgttattg ctgtaatcag tacagtttta gctacagcca gttctacaat ggcgggttat
     5941 gcattagcaa agtatcgttt tatggggaat aaactgttgt tcaatacagt tatgctatct
     6001 aggatggtgc ctttttttac cacattgatt cctttatttt acattatgag tcgtttagga
     6061 ttatcgaata cttatgcagg tgtgatcatc ccttcgattg ccagtacaac ttcagtgttt
     6121 atgatgcgac aatatagcag tcaatttcct acagcactga tggaggctgc cagaatcgat
     6181 ggtgccaatg agtgggtgat ttttacgaaa atcgctgtac cgattttatc acctacgatt
     6241 attactagtg gtttacttat ctttatggga agttggaatc aatatctatt tccattagtc
     6301 atgctttcag ataaagataa atatacggtt cccttaatta tcaaaaatat gacggtttct
     6361 agtacaggtg agccaattaa ttatggcgca attatgctaa ttttagcaac ttcagtgatc
     6421 ccaatggtct tgatttatgt gtgggcgcag tctaaattta aggagaatga cattggagct
     6481 gcaaataagt aaaaaaaata acgaatgtta accatctagt tcgttctagg agcaactcca
     6541 cattcataaa aattaaaaga atggcgggat atccatgaat gaacagacga aggaatggtc
     6601 aagaaaaatt ttgaatgtag cttctgaaaa gatagatgcg gaattagaca gaatggggaa
     6661 taaaattcca tatatttctt acaacggaaa atatacagac gtaataaagg acagaggaat
     6721 cgactggtgg accaatggtt tttggagtgg tattttatgg cagctctttc acaagacaaa
     6781 acgagaaaag ttcaaagagg cagcaataca acaagaacaa ttattagaat ctgccctgta
     6841 ccatttttca gacgttcatc atgatgtagg ttttttattc ttaccatcgg ctattgcaca
     6901 ttatcaacag tctcaaaaca aacatagtcg acaactaggg ttacatgcag ctacggtact
     6961 tgctggacgc tataatattt cagggaacta tttagtagca tggaatgacc ataaacctgg
     7021 ttggatgatt attgatagta tgatgaattt accattactg tattgggctt cgagggaaac
     7081 tggtgatccg aggttctcta aaattgctcg gcagcatgca gatacaacag ctaagtatct
     7141 agtgaggaaa gatggatcaa ccgggcatat cgcagaattt gatgcagaat cagggaaata
     7201 tattcggtta cttggcgggc aaggatacaa tgagaattct tgttggagca gaggaaatgc
     7261 atgggcttta tatggattcg cgttaagtta tcgttacaca aaaaatccgt actatctagc
     7321 tatagcagaa aagatagcag taaattttat tcagaaaatc gaaaaaactg gttatattcc
     7381 tctcattgat tttgctgtaa aagattcgaa tattgatacc agtgctggag tatgcgctgc
     7441 atgcggtctt ctggaattag caggatatgt ttcctctgta cgatcaaaaa tgtatcatga
     7501 agctgctatc aatatactcc aaaagacaga aaagcactat gcaaattgga atatggatga
     7561 agatgggatc attggaggcg gagcagaagc ataccataga gaactgactt ataatgtgcc
     7621 actgatctat tctgattatt tttttattga aggcttactt cgattagaac agtcggaatt
     7681 agctatttgg tagtaaaaag aggagaaaat acaatgaaac atccagtacc actattaagg
     7741 accagacagg attactttga cttatttaaa aagataaatc aaccactcca gccgttttat
     7801 cgagcaagtg gcgcacaaat tgattatata catcaagggg taggatatgg aaataaaatt
     7861 gcaggaatgg aaggattctc tcgggtttta tggggagcgg ggcccgcaat tgaccaatta
     7921 gatgaacgat ggttgaaatt aattctatca ggaataaaag ctggaacaga tccttcccat
     7981 cccgattatt ggggagaaat acatgaaaga gaccagcgta tggtagaaat gcccgcaatg
     8041 ttattagcgt tatatcatca tgaacaatta ttatggaaaa aattagatac aggagaaaaa
     8101 agccagatta ttcattggtt ctcgcaaatt tttgaatatg aatgtgcaga tggtaattgg
     8161 caatttttta agataattgt cggaacaatt atccaaaaat ttggttatcc agttaaagaa
     8221 tcagcactga aagaagcatt tgataatata gaaaattgtt atcttcaaaa tggctggtat
     8281 cgagacagtt caagaggtcg ccaagattat tataatcctt ttgcatttca ttattatggt
     8341 ttgatttata gcgtactaga accagaaaag cccattagcc agatatataa gaaccgagct
     8401 attgattttt ctagagacta tattcatttt tttgcggaag atggtgcaaa tgtgcctttt
     8461 ggtcgaagca tgatttatcg ttttgcagtt tcaagctttt ggtcagctat gttgtgggcc
     8521 gatcttttgc cttttaaatt aggtgaaatc aaggggttag tcaatcggaa tataagatgg
     8581 tggatgcaaa aagaaatatt tgatgaaaaa ggtatcctga atattggtta tacctaccct
     8641 caattgacat tgactgaacc ctataatagt acgttatctc cattatggct gaataagatt
     8701 tttttattgt tggcgctacc tgaagaccat gagtattgga cggctaaaga aatgcctatg
     8761 cctattcgtg aaggaactaa acttctttca gaagccaatt tgctcataca acatgataat
     8821 ggacatacat tttttttgaa tgcgggacaa ttagggccaa atttccatac attgaccaat
     8881 gaaaaatatt taaaatttgc ttattctagt caatttggtt tttcgatacc gcgagcgaat
     8941 caattgaaag cagaaatggc aatggattca atgctaggga ttcagcgagc ggacacatat
     9001 atcacgacca gttttaagaa tgagagcatc aaaacctatg gacagttcat cgttcgaaat
     9061 aatgtacgag acattgtatg taagaaagag gtacttgcct ctacatggga acctacttta
     9121 caggcaaaaa tcagaacttg gcttattcct tttgaaggct ggcagattcg cgtacacaaa
     9181 gtagaattag atacagaata tgttctatat gagacagggt ttgctattga atgttctcct
     9241 gagaaagaag gaataatcat agaagaagac aaggaaaact atagggtgag tgaagctggc
     9301 ttttcaggta ttatctgttt aagtgacgat actattaaac gaaaatccac agctattatg
     9361 ggtttgccca atacaaactt gatgacatgg gaaaacactt ttattcctgg attagagggt
     9421 acatttggaa aaggaaccca ttggctcgga acaggagtgg ttgctcatca agatcgggat
     9481 tatagtttag aagtatggaa caatcgtccc aaaattgatt ttgatgggac aaccgggcta
     9541 actatccaaa ataaaaacaa taaaaaaaga ctaaaattat gctaaaggct ggtggggaaa
     9601 tgcttgataa agtgatgttt gaagagataa tacatccaga aaaatggata aatgaatgtt
     9661 ataaagaatt aatggaaaaa gaatggaata atgagatcga gcgttgtcgc agacacacgg
     9721 agaggttaat caaacgtatc agtaacagtc agtatcaatt cccaagcgag tgtcctataa
     9781 aaggacgtta tccattaaga gacaatattg gttggacaga aggattttgg acaggaatta
     9841 attggttgtt atttgagaag acgggtgatc ctttatttca acaaacagct gaaaaagcag
     9901 atatagattt tatccacagg attgactgtc aaattatcac taatcatcac gatcttggtt
     9961 ttttgtattc tttatcaacc gtagcagatt ataaaataac gggaaatcga aaaatgaagg
    10021 aagcttcaat tgatgctgca gaaacattac ttcagcgttt ttgggagaag gcaggagtta
    10081 tacaagcttg gggagatcct agtgatcctt cacaacaagg tagaatgatc atggattgtt
    10141 gcatgaatct tccattattg tattgggcga gtgaagaaac tggaaatcaa aaatataaaa
    10201 aagctgctca ggctcatatt caaaatgcag cagattattt agtaagagaa gatggttcaa
    10261 cttatcatac attttatatg gatgtcaaag atggaaaacc aagatatgga agtacgcatc
    10321 aaggttatag tgataattcc tgttgggcta gaggccaagc atgggggatt tacggttttg
    10381 cattaagtta tcgttatttg aaagaacaaa aatattttga tttaagcaaa atattagcca
    10441 attattttat gaatcggttg ccagaagata ccatttgtta ttgggatttg atctttgatg
    10501 attctagcag agaagaaaaa gatacatcta gtatggtgat catggtttgt ggattattag
    10561 aattaataga atcaggtcta ttagacaaaa cagaaaagaa cttataccag tctgctgttt
    10621 ggaaaattat gcgacaattg aaagaaagat atgctacaac ggaagaagaa gatggctttt
    10681 taacacagtc tgtttataat aagcccaaaa ataatggggt aaatacacct tgtatttggg
    10741 gtgattacta ttatttagaa gctttagtga gaatgactag taattggtct tcttattggt
    10801 gaaaaaggta aatatggaat ttttgtttga taaaataaaa aaagaaaaac caaaacagca
    10861 tgaatggttt ctgttttggt tttttcgtta attttcatat tcttctaatt ccaagcttag
    10921 ttcttcccat tccgtcaatt ttgtttcttg atcttgtcta gcagcttcta aatcttggtt
    10981 cagctcattg agttttacgt gatcttccag gttttctggc gcgaccattt cttgttccaa
    11041 ctgatcgatc cattcatcga tccgcgccat ttcttcttca acctgagtaa tttttcgttg
    11101 aaggctacgg ataagctttt gctgttcttt gctttggtaa taatcagatt tgttcgtggg
    11161 agcaggagca gattctggct catcttgtgc caacaattcg gcgatttctt cttcttcctg
    11221 ctttttctct aaataataat catagtctcc tagatagact ttgctgccat tttcagagag
    11281 ttcgacgact tttgtcgcga tccgattgat gaaatatcgg tcatgggaaa caaaaagcag
    11341 tgtgccgtca taatcgatca atgcattttc taatacttct ttgttgtcaa tatctaaatg
    11401 gtttgttggt tcatccaaaa tcaaaaaatt ttctttgttc atcgctaact tggctaaagc
    11461 aacccgtgct ttttcaccgc cacttagcag agggattggt ttttctacat cttcgccaga
    11521 aaataagaaa gcacctaaag cacttcggat ctctttttct ggagtggtag gatgctcatc
    11581 ccacaattct gctaggatcg tcttgtttgt atgcagatca gcttgacctt gatcgtaata
    11641 gccgatggtg acatttgtcc ctagcgtttc ttttccacgg ataaaaggga tctggtgaat
    11701 gattgatttc agcaacgtcg atttcccgat accattcgga cctactagag caatcgcttc
    11761 ttgacgacgg atatctagat tgattggttc agataaggtg acattatcat atccgatagc
    11821 ggcatcttcg atttgcaaga ctacatttcc agaaggcttt tctatactga atagaaagtt
    11881 tgcttgtttt tcatcccctt gaggacgatc cagccggtcc attttttcta atgtctttct
    11941 gcggctttgc gctcgttttg tggtagaggc gcgaacaagg ttccgagcaa cgaagtcttc
    12001 taatttatgg atttctgttt gctgcttttc ataagccttc cattcacttg ctaactgttc
    12061 tgctttcaaa tctagatatt tcgaatagtt acctttgtaa tggcgcattt ttcttctgct
    12121 taattcatag acttcattga ctactttatc taaaaaataa cggtcatggg aaacaatcaa
    12181 taatgcacca gtatagcttt gcagataatt ctcaagccag gaaagtgtct cgatatctaa
    12241 atggttcgtt ggttcatcta gaatcaaaat gtcagggtgt tgcaaaagca tgcgagctaa
    12301 agctaaacgt gtgcgctgtc cgcctgataa agtatcgatt ttctgatcat aaaatgaaga
    12361 atcgaattta aacccatgca atacggaacg aatttcattt tcataaccat agccgtttcg
    12421 atctgaaaaa tcgtgttgca gccggtcgta ttcttttaaa taagaactat aagcaggtgt
    12481 gtctggcgta ccttcgctaa tgaaaatctc tagctcgcgc atccgctctt ccatttgtct
    12541 aacttgttca aaagctttca gcatctcgtt ccaaactgtt tcattggaat caagtcctgt
    12601 gtcctgagcg aggtatccga gagtcgctgt tttattttta gcgatctttc cttcatcagg
    12661 tgcttcaatt ccagcaatga tctttaataa agtcgatttt ccagcgccat ttctgccaac
    12721 taaagcgaca cgagcgcctg tactgatttc taaatgtatg ttttcaaata agacttctgc
    12781 accaaaatgg cgagcaatct gattggcttg taataatatc atggaatcct cttttctact
    12841 ttgtgaattc tcctcaaata aaaaactatt tttcaattag tagtctacca taaattccat
    12901 tatactgcga gatttgcaga aatgataaat aaatgaataa agaataaaat ttcacaatat
    12961 ctgagcaatg gaattgattt tttcctataa atactgctat gatggagaaa tcaaagatgt
    13021 aattagacaa tacgtggagg tcatttcgtg aaagatcata ttattccaaa ggcgacagct
    13081 aaaagactgc ctttgtatta tcgctattta aggattttaa ataatgctgg aaagaaaaaa
    13141 gtgtcttcaa ctgaattaag tgaagccgtt caagtagata gtgcaacgat ccgtcgagat
    13201 ttttcttatt ttggcgaatt aggaaaacgt gggtatggtt atgatgtaga agatcttatg
    13261 cacttttttg caaagacatt aaacgacgat caattgacaa atgttgcgct gatcggtgta
    13321 gggaacttgg gaagtgcttt actaaaatac aaattccatc aaagtaatag catacgtatc
    13381 agttgtgctt ttgatgtgaa tgaggaaatc gttgggcgca tcgtagacgg tatccccgtt
    13441 tatccaatgg aagatatgtc agaacaaatc aagatccaac aaatcgaagt agcaatttta
    13501 acgatacccg ctgaaagagc acaagaagta gtcaatcagt taacggaagc aggaatcaaa
    13561 ggaatcttga actttaccgc tgctcgattg aatgctccgt cagatgtatt gatccaaaat
    13621 gttgatttga cgaatgaatt gcaaaccttg atctatttct tgcattctga cgcaaatgcg
    13681 cattccgaaa atacagcaga ataaaaataa aaagcgattg aacaaatgaa ggcaaaactt
    13741 tcacttgttc aatcgctttt ttctgtttgg acaacgatta ttttgttcgg aagatttctt
    13801 cataagaaag ggaatcatct tctgctgtca gttcatctag tagataacgg atttttttaa
    13861 agtcgatgaa ccgtgcttgc cgaaagactt cttttccttg atgaaaaatc aggacaactg
    13921 gcgcagtcag cacttcaaat ttactagcta cttctggtgt ttcaaatgca tccaaatgaa
    13981 gtgccggaat atcataatgt gtgagaagtt cctctagtcg tggacgaaca gcgtgacaaa
    14041 cactgcaatt aggcatcgaa agataaatga cggcaacgga tgactgttgc agtatgtctt
    14101 gaacttcagt caagttagtg gtttgtttca tttttattct cccttttatg atagaagtga
    14161 tatgtatgag accttaattt aatgggaata acagaaaaag tcaattgaag tgctttggta
    14221 aaaaataaga gttgtgtaaa aatttacaga gcaacttgtt ttttttgaat aaaagcgtat
    14281 atttgcaaag cgaatgaact agaaataaaa aggaggaaac tcatgttttc ttttattcca
    14341 aattcggttt tgcagatgag tacgattttc ttatcgatcg ttattgaagc attacctttc
    14401 gtattattag gctgtcttat ctcaggcgcc ttacaagtat ttttgacccc agaacgtgtg
    14461 aagagatggc ttcctgaaaa tcgtatcttc tctattttta ctggttcgat cttaggattt
    14521 ttctttcctt catgtgaatg cggcatcgta ccgatcgttc atcaatttgt taaaaaaggc
    14581 gtaccagttc acacagcgtt tgcttttatg ctgactgctc cgatcatcaa tccaatcgtg
    14641 attttttcca cttttatcgc atttggcaat tcttggcaga tggcaagctg gcgggtgata
    14701 ggcagctttt ttgttgccct tgtgattggt gtctggcttg cctattttca aaaagacgct
    14761 gtattgaaag aaaaaatcac gtctaaagta gcagaaaatc accatcatca tgtccatgaa
    14821 gaagaacaaa gtgagaagaa tgaaccaaaa aatcagctga tccatcaaac tgggcatgtg
    14881 ttgacacatt caatcgacga attttttgat acaggtcgtt atttgatcat tggcggatta
    14941 atcgcagctg cgatgcagac ttatttacca actagaatta tgctaacgct cggctcaaca
    15001 aagattttag ccattatcat catgctgtta ttggccttta cgatgtctct ttgctcagaa
    15061 gcagatgcgt ttataggatc ttctttgtta agtctgttcg gcacagcacc tgtagctgcc
    15121 tttttggtct ttggcccaat ggtcgatatc aaaaatctac tgatgatgaa acgatatttt
    15181 acaggacgct ttattttatc gctgatcgga ctgattgccc ttagcgttat tggattcaca
    15241 ttatttattt aggagggaaa atatgctgcg gtttttgatt ttatctgggt atttcgaatt
    15301 gatgatgtac ttgcaagttt ctggcaaact cgatcaatat atcaatgtcc attatcgcta
    15361 cttagctatt ctttcaatga ttttatctgc tcttttggct ttagttcagc tgtatttgtg
    15421 ggtcaaaaac ggaaaagcag aagaaaaggc acacgagcac gatcatgacc atgggttgtc
    15481 aaaaccttat caacgtggaa tcgcttatgt actgctagct ttgccagtaa tcgtggggac
    15541 gttgtttcca acagttagtc tcgacactac gatcgtagaa gccaaaggat ttaatttccc
    15601 agtaagtaaa gaatcagtag gggatccgga gatgcagaca caatacttaa agccggatac
    15661 cagtatttat ttcaacaaat cagactactt agaccaaatg aatgagttga aagaaaagta
    15721 tggggataag caaactatca agatcacaga tgaaaactat ttagaagtta tggagctaat
    15781 ttataattac cctagcgaat tcattggcaa aaaaatcagc tatgaaggat ttgtttacca
    15841 aacaccgaac gatagcaata cagatatctt cttgttccga ttcggcatta tccattgtgt
    15901 ggcagattca ggagtctttg gtttgttgac gcatatgccg gaaggagtaa cggttaaaaa
    15961 tgatgaatgg tataaaatag aaggaaccat ccaatcagac tattatcaac cattcaagcg
    16021 tgaaatccca tctgtagttg ttacaaacgc tgagaaagtc tctgctccga aaaatcagta
    16081 tgtgtatcgt tctttttaaa agaacaaaat aaataaacat agctcagaca gctgacacgc
    16141 aaggacgtcg gttgtctggc tttttttgca tgatgtattc atttgtttga tatttatttt
    16201 agaagcagca tcctgaaagt atttgatatc ggtttcaaag gtgttggaaa agattgtgaa
    16261 gagaattaca atttattcct aacatgtatg ttgaaaagtt gtatgaaatg attttgatag
    16321 taaaatatcg agtggaggta ctttttatgg taacgcgtat atttattttg gatgatagtt
    16381 tggtttttga aaaaatgcta gtagaaattt tggaagaatc cagaatttta ttaagtcctt
    16441 ggaaatttga gatcgttcag ggattgaacg ttatacaatt tgttgaattc attaaaaata
    16501 atgaaatcta ttcctcagat atttttttcc tagacatcga tttgaacgcc tattatagcg
    16561 gtatcgaact aggcgaaatg cttagagaaa agaatgaaaa gtgtaaaatt gtttatctaa
    16621 cgtctcatcc gaataaagca ataactgtta ttaatcgaaa gattacgcct agtggttatt
    16681 tgataaaaga attcacttat gaaaaaaata aaaaaagcat ccaaagttac ttattgaaag
    16741 aaaaagaaaa ctatcctgtt caacatgcta cgaaaaaaag gtggacaact gtccgttatg
    16801 gtaatagcga tcactatatc cattacgatg aaatccttta tctaatgagc atgccaggtt
    16861 ataaaaataa aataggccta gtattgaaag atgaagagat tctcgtaaac ggcacaatta
    16921 aaaaatataa aaaatcactc gaatatgagt atttatgtaa agatttaaaa gcttatatca
    16981 ttaatactga aaacattaca tctattagca gagtaaacga aatagtaaca tttgcaaatg
    17041 gagaacaact agagatggga aagagaagta ttgataaact aaagaatttt atgcaagaaa
    17101 agatagaaaa tgaatcattt taaagaaaac aaagactcat atcttacctg ttagaagagt
    17161 gttttcctgt agaagagaac aacccaagta gcagcctagt cgtttctatc cttttttgtt
    17221 atgcactctt tttgacattt actccaccaa taacgaaggg tacaataaaa agtaataaca
    17281 aacaaaagga gtacagaaat gattgaattc atcaatgtaa gtaaaagtta cgggaaaaaa
    17341 caagcattaa aagacttgtc tctctcgata agacaagggg aaatttttgg atttttagga
    17401 cataatggtg ccggaaaatc aactacgatt aaaagtttag ttagtattat tgaaccatca
    17461 tcgggaacga ttttagtaga tggaatgaaa ttgacggaaa atcgattgag tatcaaacaa
    17521 aaaatcggtt atgtgcctga ttccccagat atttttttac aattgacggc tggagaatat
    17581 tgggacttga tttcagctgc ctatgaatta gacacacaaa aaaaagaaaa gcgtttagca
    17641 gaattgacag cgctttttga tatgtatagt catcaaaatg aaacaatcgc aagtttttca
    17701 catggaatgc gtcaaaaaac gattttgatc ggcacgttgc tgccagatcc agatatttgg
    17761 gtattggatg aacctttgca aggacttgat cctcaagcag catttgattt gaaagaaatg
    17821 atgaaggctc atgccgcaaa aggaaaaaca gtcatttttt ctacacatgt attggatacc
    17881 gcacaacagt tatgcgataa actggctatt ttgaagaaag gtgaattgat ttatcagggg
    17941 gcagttagtg aattattgaa tggctcacct gatgaaacgc tagaaaagat ttatttgaaa
    18001 atggctggaa ggcaagcgac aggagatgga ccgtatgtat aagcgacaat tattagaatt
    18061 aattcgagtt aatcttttat atgttaatcc acagctcacg aataaagcaa gagagaaagg
    18121 aaaaaaggga aagcgattaa ctatctatct tttgtctcaa aatctttttt cagggctgat
    18181 ttttttactg atttacggat ttgctatgtt tgctatgaac tttgttaaat tgccaggttt
    18241 ctttacttat tacgtggcac tttttggtat gttaggttta actcaaagta tatcagtcat
    18301 ttataatatc ttttttgaag gaaatgacct gcaagtattt ttgcctctgc cttttggaca
    18361 agaacaggtt ttttcagcaa agattttggt agttgctttg accatcattc cttttgtttt
    18421 tccgcttcta gtcatgttta ttttaaccgg atggcgagct gatctaggga ttttgcttac
    18481 tatcattatc tcaatccttt tgttttctct atttttgatt attctttttt gtctggctag
    18541 tttgattgtt tttggtttgg ctcgaacagc agtgtttaaa aaacatagaa aaacagtttc
    18601 tagtatcttg cttggcagct cgatgctgat cgcatttgct ggaatcatgt ggatgaatca
    18661 tcaaacgggg actattgaaa atgagttaac agatcggcat ccgatttcga tattattgcc
    18721 attctatgat gctgccagtc agccactttc tcaacaaggt ttattgggtt ggggaatact
    18781 agctatcacg gctctgggat ttttccttgc tgtaaaacag ctgatagtac caaagcttac
    18841 agagcaactg actgattcaa acagtgagtt caaaataaaa agaacccata aaaagaacca
    18901 aaatgtgcat cagcttttat ttagttacaa tgctcaatta gtaaaagaac ctaatttgat
    18961 tatgcaagtt ctttcttctt ccttgttaac tccaatcatt tttattcttg cttttgccct
    19021 aggaggcgaa ataaaattaa ctgatttaga taataagtta atcggtgttg ttttcctggt
    19081 agggatcgca ttggctttct taacagttaa tcagacttct tttatcagca atcttatttc
    19141 tttggatcaa gaaaattttc tgtttatccg ttctttgcca atctctatga accaatattt
    19201 aaaagaaaag ttcagattcg gatggatatt gcagagtttt ttaactggtg ggatcgcatt
    19261 attaagcgga ctgtcttttc agctgccttt gttttttatc cctagcttgc tatttggttc
    19321 tttattcggc tgctacttat tgtcactacg ttatttcgct agagattatc ggttgctgct
    19381 gctgaactgg accaatatta accaattatt taacagaggt tcaggaagtt tgggtttagt
    19441 cgcaactatg atgggttcat tgatcatcag tattattctt atcgtcttat acggaatgtt
    19501 ggctttgttt tatccatttt ggttagtgaa tattcctgtg atcggtttag ttctaatact
    19561 ttccgctcta tggatcgttt attatcaacg aacgttttgg aaaaaatttg aataaagaag
    19621 aggggccgtg acaaaaatca tgtcgcagcc ccttttttac agatagaggg tgttcaaaag
    19681 tcagtttctc agtattaagt caattttatg taaaaatgtg agaagctatt tttacaaaac
    19741 tttttttaat actcataatt acttcttatt gctcctgcgg ttacttgtcg caatgtttgt
    19801 gagatatttt gtcatcgctc aaggctgaac gtctctttca caaccttttc tttgttacac
    19861 ttcgtttatt taaaaagccg tttttttcgt ttcatcatga ttgcgtcacg ctttactttg
    19921 aaattacgga tgttatggtt aaagacttct gataatacaa gacctaaagc gattgctcca
    19981 gcaatcataa ttgcttggac cgcataatga gccgcttctc gataggattc agtaacgaga
    20041 tttcgaaccg cttgataagc taaaccacca gggactagag gaaccatccc gggaatattg
    20101 aaaatcgtta cgggcatttt caaacgttta gagaaaagat cgctgatgaa tgctactcct
    20161 aaagaaccaa gcaatgaacc aaaagcagca gatccgccta tttgaacaca gatccagtag
    20221 atcatccagc caaaagcacc agaaagacca caacaaatca atgaacgcct aggtacattt
    20281 gtaataacgg caaatgccgc agtcgctaaa aaactaaaag aaaactgaat aaatatcgtc
    20341 cccatacttg tgttcctttc ctaataaaaa agctggaaaa taaaagcaat cgcaaaaccg
    20401 atcatcgtag cagtcatcat cgcttctgtt ccgcgagaaa ctcctgagac ataatgtcca
    20461 gctagcaaat cacggatagc gttcgtaatt tgaactccag gaactaaagg catcacacat
    20521 ccgataatga ttagatcctg attgcttcct aagccaaaac gtacgctgta gatagcggct
    20581 atgccaatca ataaagaaga taaaaattcc gataaaaatt tgattctaaa aaatttcaaa
    20641 ctatatagat aagctgcgta tcccaatcct ccaatgacta aagtcacagg taaatcggtc
    20701 atctttccgc caaataacac cataattgtt ccactgatca ctgccgcgct aacgatttgc
    20761 aaccagacag gaaagaaaga acggtctcgg tcgattgctt gcagttcgca gtaaagttct
    20821 tctaatgtta gctctgaagc aacatattta cgtgaaagat catttacttt tactactttt
    20881 tctaaattaa tcgaacggtt ggtaatttgt tccattcgga tggtcgaggt acgatcaaga
    20941 ccaataaaga gaccggtttg agtgacatag ctgaccaaac ggaaatttcc agaagctaaa
    21001 gcaattcgac tcatcgtatc ttctacccga tacatctccg cattgctttc catcatgatt
    21061 ttcccagcga gtaaacaagt gtccagcaac agatctaatt cttttcccgt catagcatct
    21121 tctccaataa ttgattgatt agttttattt tactacaaaa cataccagaa gcgtaaagaa
    21181 taaaaaaact tgaggaagga ataaaagagg cgtatactgt ttttgtattg cgggtgtagt
    21241 ttagtggtaa aatcccagct tcccaagctg atgtcgcggg ttcgattccc gtcacccgct
    21301 taaaataggt tgtgaaaaag ctgctctgca acaagtaata agaacagcca agcaaaaaca
    21361 acttcttatg tttttaactt ggatggactt attaccgcag atgcaagctt ttgcgcaccg
    21421 tttaccaagc ggttgtgaaa tcagtgtatt gtcttgagta tgaagaaaat ttttgaataa
    21481 taataaatac cttacagata gagtggtgac tgattagaga cgaggaatcc gtctcttttt
    21541 tgtattttta agccatctta aaacaggttt tattttttgc tgtttctatt tctttctagt
    21601 atttatttat aggggaacat atgttaagat ttagggagct gttagtaaag gagtaaagaa
    21661 atgagcaaaa aaacaaccaa ggcgatcgtg gggatcgtcg ctgctgtgat tgcaggggca
    21721 ttcggtgttt ccaccacaca aaaagattca gatatctttc agcagattac aactattttt
    21781 gattccacac cacaagcttc tcaagtagcg gatgtgccag aatatgatgg aaaacatcaa
    21841 gaaatagaaa tcaatgggaa tcagccggaa tttacaaaag aggatcttag cctttccaaa
    21901 ggaacatggg aaagctattc aaatattgat aaattgaaca gagtaggaca agccaatgct
    21961 atgcttggaa aagatttgtt ccctactgaa aagagagagc ctttgtatat tgacccgaca
    22021 ggttggaaac aaaagaaatt aagtgacggg caatggttat ataatcgcag ccatttaatt
    22081 ggtttccagc tgactggtca aaataacaac attaaaaact tgatgacagg gacacgttcg
    22141 ttgaatgctc catacatgct tgctcacgaa aatgatattg cggcatatat caaagaaaca
    22201 aatcatcatg tacgctaccg tgtcactcct cattttgagg ggaatgaact ggtagccagg
    22261 ggagtgcaat tggaagcaga aagcattgaa gacaaaaaaa ttgaattcaa tgtctttatc
    22321 tacaatgttc aagatggcta cacgatcaat tatgagacag gacaagcaac aaaaacaaaa
    22381 aattagtagc agctattcga attttttatg aatattatga aaaaattgtg taaaaacata
    22441 cattcaaaga aatatagcgt atactttatg aaaagagtac ttttgataaa gctacagaaa
    22501 aaaggaaaaa aacatacaaa tagtgtttct taatttattc ggaagtttgg aatatttgtt
    22561 tgtagttttc cctttcttcg agtaaaataa ggttgtagaa ggtaagctgg aattaccttg
    22621 cgggaaagag gtgtagaatc atgggtttta cagatgaaac cgtacgtttt ggttttgacg
    22681 atagtcgcaa aaaagaagtg agcgaaacat tagcgattgt ttatcgggct ttggaagaaa
    22741 aaggctacaa tccaatcaat cagattgtcg gctacttgct ttctggagac ccggcctaca
    22801 ttcctcgtta tcgtgatgct cgaaatttga ttcgccgtca cgaacgcgat gagatcatgg
    22861 aagtaattgt caaggactac ctctcaaatc atggagtgaa tttatgagag taatgggctt
    22921 ggatgtcggt tctaagacag taggtgttgc tatcagtgac ccctttggct ggacagctca
    22981 aggagtagag atcattcgga tcaatgaagc agaagaagag tttggctttg atcggttgaa
    23041 ggaattagta gcacaatatg aagtagaccg gtttgtagtt ggattaccta aaaatatgaa
    23101 caattccatc ggaccaaggg cagaagcttc catgtcatac ggagaaaaga tcaaagaact
    23161 attctccttg ccagttgatt atcaagatga acgattaacc actgttcagg cagaacgtat
    23221 gctagtagag caggcaaata cttcaagagc caaacgaaaa aaagtcatcg ataaattagc
    23281 agctgtgatg atcttacaaa attatttaga cggctcaggt aagcaattat tttaataata
    23341 aaagaaaaga ggtaatctta tgacagaaca taaccattcc cacgaccatg aaggacacga
    23401 acacatcaca ttggtggatg accaaggaaa tgaaacatta tatgaaatcc tactaacagt
    23461 tgacggacaa gaagaatttg gacgtaacta tgttctttta tatcctgctg gtgtttcaga
    23521 agatgaagat gtagaattac aagcttatgc atacatcgaa aacgaagatg gaacagaagg
    23581 cgagttagaa caaatcgaaa cagacgcaga atgggacatg attgaagaag tattcaatac
    23641 attcatggcg gaagaagaag aatagactat aaagctagga gaaaccttga tatgataggg
    23701 tttctccttt ttttattttt tactgtatgc catattgtat gccatctagt caatatttaa
    23761 gtgttgtact aatttttcaa cagtcttttc tttcgtttct tttgccaagt gaccgtaaca
    23821 atcgatcgtc tgactaattt ttgtatgccg taatctagtt tgaacttcta ccatagtagc
    23881 tccagcgtcc aagagcattg aagcatgagt gtgtcttgct acatgcacac cgagaaatgg
    23941 aaccatagct ttttcacaaa tagtaatcaa tcttgcataa atagcgtggt gtgtgattag
    24001 ttctttatag ataccacaaa aaatcatagt cggatcagtt acaccaagtg tcagcatata
    24061 tttccgctga ttaatctgcc atttttttaa tatagaaatt gttctttcat ctagtggaag
    24121 aaccccagca ctacaatcag ttttaggatc actgatttta tagccatttt tggattggct
    24181 tagtgtttta ttgatggtga ccgtattttc ttgaaaatca atgtctgacc aattcaatgc
    24241 aagggcttca ctgatcctaa ccccgctata aaagagaaag cgtagtaacg ttttatcaaa
    24301 gtcgtttcga taagtttcag gtttgctgtt taggtaatca aacaaggtga tcagttgttc
    24361 tttactgtaa actttgacct tttctttatg cttagtggtg gttcttttag gcattaatac
    24421 gttgtctagt ggattagtct caataatccc aagattgata gcgtagctaa aaatacgctt
    24481 agaagttgaa tgaagtacct tgtattggtc agtagtttca gcccagctat ttacaatttg
    24541 ttgggctttt tttaccgtga cttcattcac acgaagattt ccatattttg gaagaatcca
    24601 ctttctaaac ttgatttcag ttttcatgaa ggtggcttct cggacagtgg ttttatatgt
    24661 ttctagccac aagtcataaa cttctttaaa cgtttcgttg ttcgcttttt taataccgtt
    24721 tttatcgtag tccacttgca agcgtgacaa ggcaagctgg gcttcttttt ttgttttgta
    24781 acctcgtcta cgaaccttat caggtttgcc agtcattttg ttcattccaa gataggcttc
    24841 atagagccaa aatttacctt ttttagtttc atattgcttg aatgttgcca taatagtttt
    24901 ccctccatag tgtagcaagc cgtgggggcg gttggaggag gcagtttatt attattttga
    24961 atagtgttta tttagctcag taacaagagc tgtgaactct tttagaagat cattttcata
    25021 aaattcttga tactcttttt tctcatctgt atttttttct gaatcattaa ttaatgagtc
    25081 atatcgtaaa agcgtattta gaagagctgc gagataagca attggggtac tcccgtcagg
    25141 aaattcaatt cgagatcctg ttttaagata ttttattgcg tttgttaaat aaatcttctg
    25201 tgagacagtc aggttatctt cttcgatgtt attgatagca ttagaaagat tagaatcaat
    25261 tatagagtta tttttttcaa tagttttttt caattgcttt tcaagcacat ttcgcttaat
    25321 ttcgggcatc atatgcatat ctcttaatgt ataagatccg tttaatagat aggtagtgga
    25381 tacatctaat acctttgaaa gttgtttaag cctggtgtta ttgggaagat tatagccatt
    25441 ttcccaatta ctaacggcac ctttactggc cggtggggat aatttacctc caagttgttc
    25501 cattgagagt cccttttcaa ttctagccag tctaattctt tgtcctgtct ccactgcttc
    25561 ggggtatttt tttctagcca cattttcacc accattcata tattttctct actatatcac
    25621 gatttaaata tgtgtgaaac ataaaagttc aaaaaagtat gttaaaattc ttgcaaatga
    25681 aaaggtatga tggtatattg agtttataag aggtatagaa atgtattcaa gagcctcttg
    25741 cattttttta aaatctttgt atagaaatgt atgctaacga ggggggataa atatggaatt
    25801 aaaaattgac aaactcacgc ttgatgatcc agcttttaaa attattgacg atcgagttgt
    25861 tcaacaagta gagcaaactc aaggaacgtt actttcatta ttagaaaaaa agtaccagtt
    25921 tccaaaatat atgaacaagg cacaagctgc taagtatatg aacgtttcat acaatactat
    25981 gatgcagaaa tatgttccta acggtttaaa gttgattata gttgatggag tcgtaagaat
    26041 ttcacaagat gaatgtgatc gctttatgga agaataccaa aaataaacgc aagccgtggg
    26101 ggcaaaggga ttaataggag gaaataataa tggaatcgac acaaaataaa gcaatcgaaa
    26161 aagtattatc aacaattctt acagaagaca cagcggcaga attagcaaac ttggaaggca
    26221 aagcgctaga agaaacgttt gaatgtttgt acgaacaaat ggactatcaa aaattgctac
    26281 cacaagaacc aacggtaagc ggagtattgc gtggcttgaa cgatttagta caagcagagt
    26341 ttaaagaacg actttctatt gaagagtatc aagaaatttt gtatcagcaa gttgagttgt
    26401 tagcgagctt gctagggctt gaactggagg acgttgaatg aaaactgaaa tttggaacgg
    26461 acacattata agatttgtcg atattaatga tgaatggtgg gcagtggcga aagatgttgc
    26521 ggaagcgtta ggtcttaaac aggttactag agccattcac tctttgccta aagatggggt
    26581 tactactagt aaggtcatcg attcattggg cagaacacaa gatgtaaaca tcatcaacga
    26641 aaaaaaatat ttaccgcatg gcattcaaaa gccgtaaaaa agaagccgag gcatttcaag
    26701 actggatttt cgacatcatc aaagaactac gccagtccac aggacttgaa ggctttcaag
    26761 tattccgcat gctagacaaa gaacaccaaa aagaagcaat gactaaatta agccacgcta
    26821 ttactgaacc aaaaccagta gactacatta aagcgaatgt gatagccaat aaagctgtat
    26881 caactattta tggtcattcc aaaatggtaa aaaagaaaga tatgactcct gaaatgttgg
    26941 ttgatcgtga acctatttta gatgagacag tagaattaat gactgttaaa gaaaaatatg
    27001 ggttgcagtt ttcagtgagt gagaaaattt ataatcgttc tgctgaattg cagacaactt
    27061 aggagcatta acatgatcga gaacaaagaa aaagccttat ccataacagt cttggcggac
    27121 aggataaagg caacttaatt gggataaaac ccgatattct ttgttccgat tataccatat
    27181 taaaaaatcg gagggaacca ttatgaaacg aaacttaatt ataggaagca ttttaatcgg
    27241 cggaattttc ggcttattac cattaattgc aaaaatagct atctttgcag gattagcgtt
    27301 atatctcttc actgcttatg acgagtacga ctatcaatta agaactggag ggcataagta
    27361 gatgtacaaa acaaaactat taaaccaact cgatagcctt gaattagagg aaattaatca
    27421 agggatcgct gaactagaaa ataatatcgg gaaaacctac tttggaaatt cattcaatga
    27481 aaaactaaca gttttgtatg tactcaaaaa acatgcagaa cacaaaataa tttgtcgaga
    27541 aatcaacgag ctaaaaaatc agattttaac cgcatggtta aacattactg atatgcaaga
    27601 agcaagggtg aaaacattta atacatgggt aaagtatcag aatcaattaa aaggtgctga
    27661 atttgttcgg gatgggttga aatacgaact tgagcagttg aagctcatgg aggtgtctga
    27721 atgatttata ccagtatttt gaaaaaggag gagaggttta ttggcaaata attatcaagc
    27781 agcaacggaa ttacaaaagt cgggatggtc aatttatccc ttatctcctg gaactaaaat
    27841 tccaataaaa ggctctagtg gttggaatga tgcaactaac gattctaatc aaattaatga
    27901 atggtggacg gaagatgcaa ctagaaatat tgggttaatg cttgaagatc atcaaatggt
    27961 ggtagttgac ctagatcaac attctgaaac acgaaacggc gttgagaatt ataaaaaact
    28021 tgcttcaatg tatgatccat ttccttctac ttatacggaa atcacaccag gtaaaggaat
    28081 ccatttcttc tttaaaattc ctgatggtgt aattatccaa caagaaacag gtgcatttgc
    28141 tgatatcttc gggcgtgatg ataaaggtaa aagtttaagc gggattgata ttatcactaa
    28201 aggagttcca atagcgccaa ctatgattat ttcaagaagt gttgggagag catatgaacc
    28261 tattgaaaac gtatctctaa ataatattgc accagctccc gattggctag tgaacctact
    28321 gctaaaaaaa ccgcaagaaa taaagactca ataccgaccc gtagcaaaaa cagggacagc
    28381 aaaaaaatta gatatgattg ttcaaggcgc tggcgaaggt agtagaaacg atcatttaac
    28441 taagttatgc ggttggttac tatggcacgg tgtagataat caaactttag cagaattgat
    28501 ttatacagca aatgcgtaca atgaaccacc gctaaaagat aaagaagtga atcaaattat
    28561 tcgatcgatg attaaaaaag atttgagggg gaaagctcat ggctcataag cataaattag
    28621 atagtatttt agactttccc gaagccagcg agcgtgaaga caatatcatt gaattgaaaa
    28681 cctggatgtc acgattaaga tgcaataaag acgatcagat taaaagtaac agtgttgtga
    28741 atgcagaatt gattttaacc aatgatagca atttagctgg aacaattgct tataacgaat
    28801 ttagcggata cattcaccta ttaaaagatt ctccttggat caatcgtacc gctggagaat
    28861 gggaagacag ttttgaggat gccttaacgg catatattga agaaaactac aatgtagttt
    28921 ttgatgacaa caaaatacac aaagcagtag taaatgtggc tagaaagaat gttttcaacc
    28981 cagtaaaaga acgtatcgaa aaagttaaat gggatcaaca gcctagactg gaaacactgt
    29041 ttattgacct tttaggggta gacgacaacc tttacacacg agaagtaaca aaacgttgga
    29101 tagtcggatc agtcgcacgt atctataaac caggaataaa gtttgagatc gttccagttt
    29161 tggatggacc gcaagggatt ggtaagagta ccgttccagc attactttac acggatgatt
    29221 ttttcaccga ttcattagat tcgctaggtg aaaagaaaga tgattatatg cagcttcaag
    29281 gcaatgtaat tattgaactt ggagaattat cttcaatgaa caaaactaaa attgaacaga
    29341 taaaaaactt catcagtgcc aagatcgata aaattagacc tccttatggt cggaatgtca
    29401 tagcttgggc aaggcaatgt gtatttattg gaacgtcgaa tgatgggcag tatttgaaag
    29461 atgatacagg aaaccgccgt ttttatcctt tgccttgtaa gaataagcca aagatgaatc
    29521 cgtttaaaac aaaggatgaa tattttcttc aagtgttagc tgaagcaaag gtgctttttg
    29581 ataaaggaca acgaatctat tttagtcccg atgaagataa agaagtctta gaaattgcaa
    29641 aagactatca agaggatgcc aagatggaga atccaattaa agaagcaatc actaaatatt
    29701 tggaaatgga aatcccgtat aaatgggaag aagctccagc gtgggcgaga cgttcttatt
    29761 atcagaacta tcctgacagt aaatgtaatg agaaaaattt acagcatttc tataatggag
    29821 ctactatgca acaagagttt tatttagttg atagcgtact caccgctgat attttggaag
    29881 ctgtttttga taaacaagca aaggatttat tgaatggtcg atcagatgca gaaactaaaa
    29941 agattgcctt gattattagc agtattcctg gttgggaacg gaagcaactg ccaaaaagaa
    30001 ataaacgacg aggattttac aataagtcaa atgcctatga aaataaaaat cgagctggaa
    30061 agtacaaaaa gtaacgggta gtaacgggtc agtaacacct agcccgttac tagtttaccc
    30121 ttactgcccc aagggataca gcaatttggt aacggggtaa caccttattt ccttaaaact
    30181 tttgaaatag ttagctaata tgctggggaa taatgttact ggattttacc cgttacctgt
    30241 taccaaaacg ctagaaccct tgtccccgtt gggattgagt ggtaacgggt acctgttacg
    30301 taggtgttac cacgtgttac gaatcaagga ggaaagtaaa tgctcaatat tatttcaaca
    30361 aacaaagcac cgaactttca atatacagat gaaatggatc ggtttctaat gaacacgctg
    30421 gcatttagtg tgggattggt aacagaagat tattccacat ttgatccaga agtattaaag
    30481 ataatggaag aagaacctga ttggctgcag gagtcagtag cgtggtgtca atcgctagta
    30541 gtgggatcat tggtagatag tggcaactat gatgatacag gtgagctaat ggatgaattt
    30601 aattgtctgc ttaacctata tgatcgagcg agacaacgag agcttacatc gaatgaggat
    30661 aatttgtttt taaacatcca tgataagttc ttggctttgc tactaacaga tgatgaattg
    30721 ataactaatt tattggaggt agaataatta tgcatatgga aagtattaga tacttcgatg
    30781 gtgagaaaca cattgagtat tcaaacactc aagaagatgt agactttatt agttttgagg
    30841 aagataaaat cactaaagtt aattttaaag acggaacgtg cttgaagata gtttcgcctt
    30901 atattgaata caaatcaaaa tgggaacaag atgattctga cgaacgagat cgctttggtt
    30961 ggtaatctat ggcagttaaa aaacaatgta atcatgctgg atgtaaaaca ttgattgatt
    31021 ataggcagaa gtattgtggg aagcataaag caaagcaaac ggcaattaag cgtgaagaaa
    31081 gaaagcaaag cgaaggtaaa tattttcaat tctatcaaag tagaacatgg cgaaaggctt
    31141 catacttgta tcggttaaat catccagtat gtgaggattg cctagaagaa ggcttgataa
    31201 ggaaagctga tgttgtagat cacaaaattg aactaaaaga tgattggaat agacggttag
    31261 atgaaactaa ttttcgttct ttatgccatg cacaccataa ttccaagaca gccaatgaaa
    31321 gacaaagacg agaaaagagt accctttgag ttaagggggc atagtgtgaa acttactgac
    31381 aatcgatgcc tactcatttt ggtacaaata accgttgtga aaaggcataa gggtaattac
    31441 aaataacgat tacacttgta atcacaagtg aaaaagtata taatgaaagt aggagattta
    31501 ttgaaaaata caattgttat tactgataaa acagggaaac agcgcaccat tgagttacct
    31561 cattttggtc aagtgaccat tcaaatgcag aacggaaaaa tcatttatat agataaatta
    31621 gataaagaaa aattctgatc gaaaaacgaa ggaatgtgag cttaattgct tacgttcctt
    31681 tttcttttgt ctgaaaggag gacaacatgg gacaccctaa aatattacac gatacaaaag
    31741 gcaatatatc aagtgaagaa aaagcaatcc gtgtggacgc tagagaagaa ttgttcaagc
    31801 agcaaccatt aataaatatc acgccccctg actggatggc agcgagcgct agaagtgaat
    31861 ggaatcgtat cgtaccaaca ttaaaaaaag attatccatt gagtgaagca gattatggtt
    31921 cattggtagc ctattgttta gcctttgctc gaatgaaaac agccgaagcc gagataagaa
    31981 aatcaggtac gtttatcaca tgcgaaaacg gagtaaagaa agccaatcca gcggttcggg
    32041 ttcaatcaca agctatgagt gatttgaaaa aacaagccac ctcactaggt atgaccttag
    32101 aatcacgatc aaaactagct ttgaacaagg ttaaaaatga tgaacccgaa gacccgttca
    32161 aagagttgat gaattcatga atgattacat tgagaaagtc ctatcaggta agctgattgc
    32221 acccaagaaa attatccaag cgtgtgagcg tcatataagc gatttggagc gttctaagtc
    32281 agatagcttc ccttatgtgt tcgatgaaga acaagccacc aaagcgatta aattcattga
    32341 gttgctacca tctacggacg gtaaagcaat caagatgtta ggatttcaaa aattcattct
    32401 aggcagtctt tatggctggc gtactaaaga agggaattac aggcgattca atcgagcgtt
    32461 taccagtatg agccgtaaga atgggaaaac gtatatcgca agtggcatgg ctgccaatgc
    32521 gttgattatg gaacaagaac cagcagaagc aaggcaagta ttgtttgtaa gtaacgcttt
    32581 gaaacaagct aaattgggct atgatatgct gtctaattca cttagaaacg tggtcaagtc
    32641 tagtaagttt ttaagaccac aactgaaaat tatgaactct aagattcagc acttgccctc
    32701 taattcgttc gctatggcac tggctagtga aaccagcacg ctagatgggt ttgcaccaac
    32761 aaccgcaatt cttgacgagt ggcacgaagc aaaaactcgt aaaacgtaca acgtcattaa
    32821 gtcaggaatg acccaacaaa agaacggctt attgtgtgtt attagtaccg ctgggcttga
    32881 tttaaacgtt cctatgtacg aggaatactt attgttagat cgtgtgctaa aaggcgaaga
    32941 acaagccgac aggtacttta tagcgatatg ggaattggac gatcccgaag aaattcacga
    33001 tcaagagaaa tggatcaaag ccaatccgat ttttgaaagt gaagaaatca aaaaagtaat
    33061 gattccaacc attcaagatg atgtgaacct tgctttgaaa caaaataacc ttaattctgt
    33121 attggtgaaa aacttcaatt tatggagaca agcgagtgag gacagctata tgattgctga
    33181 agactggcag gcaaccgaag tagaaccaca agatattaca ggcaagcccg tttatatcgg
    33241 agtggattta tctaaaacag atgatttaac tagcgtttca tggatcgtac cgctagataa
    33301 cggcgaactt tattgtgatt cacatagctt tgtagccacc aaatatgggc ttcaagacaa
    33361 agaaaagcgc gacggtttgc cttatcgaga actagaaaaa gctggtgagt gttccattac
    33421 tcaattagaa agtggaatcg tggactatga ccaagtattt cagtttattc aagatttgat
    33481 tcaagaaaat gatttggaat gtatggggat ttgttatgac ccgtataacg ctaattcgct
    33541 tatcagtaaa gctgaaaaag ccaactaccc aatgttagaa gtaagacaag gaacgattac
    33601 tctaaacgtt ccgacccgaa cttttagaga acaagtttat gaaggcaacg ttattcacaa
    33661 taaaaatacg attctcaccc atgcagtgaa caacgctatt ttaaaaacgg ataacaacgg
    33721 cattcagatt aataaatcaa agaacagtaa caaaattgat ccaatagctg cattaatcaa
    33781 tgcctatgtg tttgcaatgg attacttcac cacaacggaa ggagcgaaag cagacaatga
    33841 attttataca agtgaagaat tttctttcta attacattca taccgttctt ttacttcttg
    33901 gattggtgtg tgtgttggtt gctatcacct tactaacaaa tgtctactat ggcttgttag
    33961 cgctgggcat agtgcttatt ggggtagcgg tcatgctaaa tacagaacag aagggaggtt
    34021 aaaagatggc attttttaaa gcgagacaaa atacaacggg agatcctttc ctacaacatg
    34081 tggtatcaat ccaatcggat gattacacca ccagctttac aagcgttcgt gcattaagaa
    34141 atagtgatgt gtttgcagcc gttcgaatta ttgctagtga tattgcttca agtccgattc
    34201 aattggtcaa aaacaatatg ccacaagctg ataatgaact ggtgaagtta ctaaacgaga
    34261 aacctaattc agaaatggat ggttggcatt taaagtttgc tttggcggtc aatatgttgc
    34321 taaacggtaa tagctttgca gagattaaac gcaacggtga aaaggtagaa gaaattcact
    34381 tattacctaa ctcaagtgta acggttactc aattagataa tggtacgttg tcttatcaga
    34441 ttggtgataa aaaaagacgt gtgaagtcta gcgatatttt gcacttcaaa tatttcaccc
    34501 aagatggttt aacaggatta ccaccacttt atgcgttacg tgatgaactg aaaattcaac
    34561 aagctggcaa ccgcacattg cacaatttct ttactcgtgg tgtcagtggg tcaggtattt
    34621 tgaaggttca taagtcagat ttagacggat cagcaaagaa cgcaattcgt gaaaagtttg
    34681 aagaagccaa cggttcaagt agtggagata atgctcttag aacgatcatt cttgatgaaa
    34741 caatggacta caaaacatta gaaataaaca ccgatgtttt gaagcttatc aattccaatg
    34801 attggaacac aaaacaaatt gccaaggcgt ttggtgtacc gattgagcgt ttaggcgttg
    34861 aaaatgaaca ttctagcacc gttcaaagta atctccagta tatccaaagt acgctgattc
    34921 attactttaa tgtgtttgtg agtgaattag atacgaaact tgaaaccaat atccgcttta
    34981 attccgatca gttactagag actgatcctg aaacaaaagt aaaaaatgta ttggatcagg
    35041 tcaaagggtc acttctcacg attaatgagg ggcggtcgaa aatggggcta ccccccatgg
    35101 atggtggcga tcgtttacta gcaagtttga actttacgta tttagatacg ttggagaaat
    35161 atcaattaaa agaacaggaa ggagttacac cagttgaata atgaagaaga aaaggaaaaa
    35221 cggctgacag aagaagctga gctaacagcc gattctccca aagtagagaa agaaaatgaa
    35281 aaacaaccaa cagacggcaa aactatttca ggctatgcgt tgaaattcgg gcaaccgtca
    35341 aaagatttag gcggctttgt agaagtgatt acacccgaag cattaaaaga ggtggattta
    35401 tcaaatgtgt tcttattata tggacacgat tattcaaagc cactagctag tgtcaaagca
    35461 ggtacgttga aattgaatgt cgatgataca ggattacatt ttgaagcaga gctaaccgac
    35521 acgacctatt caaatgatgt gtatgagaat atctcaaaag gggttgttga ttctatgtcc
    35581 tttgggttcg tgcttggatt agattcattc gacaaaaaag aagatggcac aattgaacga
    35641 tcaatagata aaatcaaagc acttaatgaa attagtgtcg tgaccgttcc cgcttatgat
    35701 tcatcaaatg tccaagtaaa taagcgttct tacgaatcgt ttatgagtaa caaccaagca
    35761 aaacaaacaa acaatagctt agaatccact tctaaagcac aaaaggagag taataacatg
    35821 gaaaaaactt taatcgataa cgaaaaaaca gaattgcgtg ggtatgaaga atatatccgt
    35881 tcacaaggcg aagtgcgtga tggagtcact actgtaaatg cagcggcagt tgttcccgaa
    35941 gaagtaatcg gtgaagtctt tgatttgaaa cgttcaaatt ataacttagc tcaatatgca
    36001 acagtaaaaa cagtatcaaa tggacaaggt aaatatccag tagcaactaa ccaacaagca
    36061 gtgttagcaa caaaagctga acttgctgaa attggtgata ttgacgctga aatgtttact
    36121 tcagttgatt ataaagtaga aactcgtgct ggtaagattg ccttatcaaa tgaggttgtg
    36181 gaagattcag cagtgaatat tgtacaagag gtcaaagatc agttagcgaa attggtagaa
    36241 aacactgaca ataagcatat catggattta ttaaaaacat tcactaagaa aacggctgct
    36301 acgttggacg atttgaaaca actatacaat gtggcattag acccagcatt aaataaaatg
    36361 gtaattctaa accaaagcgg atattaccac ctagatacat tgaaagattc agatggacgt
    36421 tacattttac aacccgatgt gacagcacct agtggtaaat cattattcgg tatgccagta
    36481 gtattgattg cagatacatt gtttgccaat cctaaagctg gaacattccc tatgattatg
    36541 ggggatattg cacaatctat ctttgttgct cgtagaaatc aagtaacgac tcaatgggaa
    36601 aaattcgatt actactcaca aggacttgca gtgatcgttc gcaacgatta taagaaaatt
    36661 gatcaaaatg cttcagtgta tattgagttt acgccagttg taacaccaaa agtatagaaa
    36721 aatattgggc ggcggtttat cccactgcct ttttttcatt aggagagata aaatggtaat
    36781 tttggatagc ataaaaaaaa gtatgcggat cgatcacact attgatgatg actttattca
    36841 acaattgatt gatacagcag gcgaatatat aaaaagtgct attgatagta gcgcaacgga
    36901 taaagatatg gataattatc agcaatttga tttggcggtg tcattactta ctcaacattg
    36961 gtatttgaac cgtcaagaag ccagcagcga acggatacca gtaacggtac aagcattagt
    37021 acaacaaatg agaggtgctt attatgccaa tcattaagaa tgtaaatgaa ttgactgaga
    37081 gagtcaagtt taaaaagaca aaacgggtaa aagatgaaga tgggcagatg gtggatagtg
    37141 aagaaactgt atttgaatgt tgggctaatg tgcgttcaca aatgctaaaa gacgtgcttg
    37201 ctagtgtagg taccattctt gaaggaacgt tgacgtttat tattcgatac gatcaagatt
    37261 atgaactaac aaacgatatg aaagtagctt ggaaaaacaa gagttataaa attatttcaa
    37321 tcaatgaagg aacggcgttt aaagattata caacgatcat agctaaacag atttcttaga
    37381 atgattacac ttgtaaacgt tgtgggtatt tagtataatt aaggtagtaa atgaagggtt
    37441 agctgcctga attttgcaag acttagctag tcgaaatcta ttgttggact gaaaattgta
    37501 ggtgtggttg caaacatgct ggactaagaa agatgataga tgatgaacgt tcaattttaa
    37561 tacaggcatg ctaggactga ttggatggtt ttggcaagct gattgtgtag aaatcaaaga
    37621 acacgtctgt tgtggacgtg ttttttttgt tataattcaa aagaggtgat ttaatggaca
    37681 aagcagagtt tacaaatttt tattggaagt attatctaca tttagaaaat gagtttatta
    37741 ataccacaga ttttgtgatg ctcgatgaga ataatttcaa aacattctct attgaatatc
    37801 aaaaactact actagcgatt ggttcggagt gtgagattat tttcaaagaa ctttgcggat
    37861 ttgatagcag tagcaataaa agcataactg attttaaagc tgttattaaa tctagcgaat
    37921 taatgtgttt ggataatggt gttagggtta tgaattcttt aacattgact tcactaaaac
    37981 cttttggaga tgggtggcct gaagatacac cagattggtg gaaaatatat aacagagtaa
    38041 aacatggtcg ttcttcaaat tataaggaag caaatttgga aaatgtgttg tatgctttag
    38101 caagtctata tttattagag gaatatttgc ataagaaagt aatactagaa ggtgaagtag
    38161 actttataag tccagagtca aatctattta cgttatcttg ggaaagaaaa cattcgtcga
    38221 tgcaaaaagt gacgtttgaa aaagtggatt caaattatgt agctccactc attgatttta
    38281 aagaacaaga agaaatttaa aaacccccac ggcttattga agtttttgta tgccatattg
    38341 tatgccattt ggtttaaatc gcttgaaaaa tagtgataga taactctaat tcatttagtc
    38401 ataaacgctg ttttgataac ctttatagtt ctttgatatg ggtttctcat tcatggcgga
    38461 agaagaagaa tagaacaaaa gaatgaatta ataagatata aaaaaaggga ttgtgacaaa
    38521 cgtcttgtca caatcccttt ttccaaataa acgatgttca atcagctgcc cctcggcatt
    38581 cgctcgaaaa acggcgaaat atgaagaact attttgccat ttgtttctct aataatcagg
    38641 tcaaaacgtt gacttcacag tctcttcctt aaacggtgtt ctcctgccaa ctcctcggtc
    38701 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
    38761 ggagctgaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc ttgcatctgc
    38821 ggtaataagt tcaaccaaac gaaaattatg aggagctatt tttgtttggc tgttcttatt
    38881 acttgatgca ggacagcttt ttcacaacct cttttcgttt agcactaaat ttccttaaaa
    38941 agtagaaaag ctttcgaagc ctcgtttgtt tcttttactg tataataaaa gaaaagagta
    39001 acaatcgcta aaagatataa acaagagaaa ggaaatacaa gatgattggt ctgatttatt
    39061 ttgtggtgat cgttctggcg aacacagttg gcgctatttc cgggatgggt ggaggcgtgt
    39121 tgatcaaacc gattcttgat cttatcggcg cccattctgt tgcagggatt tctttttact
    39181 caacagttgc ggtattcacg atgtccattg tttcgactgt gcgacaagta tcaagcggga
    39241 aatcactgaa ttggcagatt gtcggttggg tatctagtgg agctgttgtt ggaggagtag
    39301 tcggcaacat tgtattcgaa gtttttttac agttatttga aaacgagaag catgtgcagc
    39361 tgatccaaat ttttttgacg gtattgacct tggtttttgc gttcttctac accaagcatc
    39421 atcagccaaa atttcatttg acgtcatgga cttggtacct tatatgtggg gggggttctg
    39481 ggctttttag ctagtttttt aggtattggt ggtggaccag tcaatgtttc tttgttgatg
    39541 ctgatgtttg cattgccaat aaaagaagca acactatatt ctctatctac gattttcttt
    39601 tctcaactgg caaaattggt aacgattgct ttaacaagta gctttatgcg ctttgattta
    39661 tctatgttgt tttatgttat ccccgctgct gttattggag gtttgtgggg agcaagattt
    39721 agcagggttt tgtctccaaa aaaagtgacc tttatttttc aagtaattgt cctcgtggtt
    39781 cttttggtca attgttacaa tgcctttgtc atcttacaaa cattaggaga atctagacta
    39841 acgcaagtca aaatcactga aacatattgt tctaaatgaa aaaaagagta tactatgata
    39901 aaaaaattca ttttaaaaaa tcagaaattg gctggtgatt tggatgttac gggaaatgcg
    39961 tttagaagat gcagaagcac tacgtgaaat caatgcggat caattagggt atgatatacc
    40021 attaaccgtt acggtgagac aaatgaagaa actgctgaag gagccagaga aaaatttttt
    40081 cttggtttat gaagatccta cttctaaaaa agcagctggc tatgtacaag cggagtccta
    40141 tgaatcgatt tttagcgatc caatgttcaa tattatggca cttgctgtgt ctaaatatgc
    40201 tgaaaaaaga ggcatcggaa aggctttgat gactggcgta gaagaagaag cgaaaaaacg
    40261 aggaataacg acaataaggc ttaattctgc agaatacaga gtagaagcac accaatttta
    40321 tgaacacatc ggttatcatt ccgataaaat gcaaaaaaga tttttgaaaa tcctgtaaat
    40381 ctttatcaaa aaaatacccg atcaccaagc cgatacttga tgatcaggta tttttgtttt
    40441 tttgactaag aaagtaattg catcaagaaa ccagagatga tcaaaacgat ggcaccacca
    40501 agtcgattgc ccatttgagc aaaagcaata agttccatcc gattagctgc agataagacg
    40561 gctacatttc ctgttccgcc catcgagttg ttgcataagc cagcagtaat agttgattca
    40621 attggatata aaccaaacaa acgaccgaca aatcctgaaa caactgaaat cgcgataaca
    40681 cttgtcagac ataagacaac aaattgccat gtcaaagcag aagctaatac attcagattc
    40741 agcaacgcaa taccgatacc ggcaagaaca gctgctgtca agtttttgac aatcaagtta
    40801 ttgaacatga tagctgcatc ttcataatac tctggtaata ggttggcgat tttacagatg
    40861 acaacgataa taatcataaa tgcgtaagca tggactttag gaacaaaata gttaccaatt
    40921 tgtcctaaga tgaagaaagt caatgatacc atcaaaccaa cacctaactg tggaatggaa
    40981 ggtttcacag ttcgaggttt tccatcgcca agatcgcctt tttccattaa tttaccattg
    41041 ccgttgaatt ttggcattga ttgtccagca cgagcaacta atgctgcacc gatgatagct
    41101 aagacatttg tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga agcatccgta
    41161 cctaaaacat ttgcataaat cgttgataaa ggaacggctc cggctccaac accaccagcc
    41221 atcgcaggta atgagatgta taaaacggaa tttgcaaaac catttccgat aagcatgccc
    41281 acgagtccta cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg aataaaacga
    41341 acagaagctt tcatcaatag attacggttc ataccaagga tgctaccagt aatcaaggca
    41401 gcaatataaa agtcccaaaa gcccatattg ctgacaaagt tttctgtgga tttcactaca
    41461 tattcaggta agatcccaaa tgtagcaatc gcagcagaag cgaagatcgc aaaaacggaa
    41521 ccaccaccca aataactttt gacgataggg atttttgtcc cgataaaatg aaataaatta
    41581 ccgaaaataa ccaaaactgc gattggtcca atcatattcg tcggtaattt ccctaaagcc
    41641 attgcaatga tcaggacaag gaccatgatc aaataaagtg gcaaacttac gccggtgatt
    41701 tttgtggacc aaaaaccttc ttttttcttt tcctcaactg cagttgcagt tgttgttttt
    41761 tgtgccattt ttacagatcc tttcttattc tgtatcatat gaaaaaagcc aaagaaaagc
    41821 gacaaaagag caggagttgg ctggccgctg ttttgccgca gtcgcttttt tctttttaga
    41881 cgtcatacaa agtttctgta tgttctttta ctataacgat cttaatcttc taaagattta
    41941 tattcaggaa cccatttagc agattcaact gcttctttga tatccgtgat ttcttcacga
    42001 ttcaagtttt gtgcgacaac tgattttgcg acagtttcag caatcgtttg agaaaattca
    42061 gtgatttttg ctactggagg caagatagct gctcctggtt ttgttacatc aacgattccg
    42121 cctaatgctc gactagcttg agaaatgatt tcagcattta ctcgtgtagc tgttgaagca
    42181 atcaaaccaa gtcctaaacc tgggtacatc aaagcattat ttgcttgacc gatttggtaa
    42241 gttacaccat tatattcaac atcagcagca gggatacctg ttccaactaa tgcttttccg
    42301 tccgtccatt ctattaaatc ttttgctttt gcttctgcca attttgttgg attagacaaa
    42361 ggcatgatga tcggacgtgg tgtatgagca gccatttctt tcacgatttc ttcagtgaat
    42421 gctccaggtt gggtagaagt accaatcatg attgtcggat ggatcgcttt tacaactgct
    42481 tctaagtttg tcaattcatc agcattagtg aaatctgagc gtttgcgagc gaatgggatt
    42541 tgaccaggag tcaatccttc tgtatcttca aacaataaac cttgtttatc tacttgatag
    42601 aaatgttggc gtgcttcttc ttcaggtaca ccttgacgga tcatctcatc taaaaggatg
    42661 tttgcgatac ccacaccagc agtaccagca ccaaatgtca aaattatttg atctttcaat
    42721 tgttcaccgg atatattcaa tccgcctaat acacctgcta ggacaacaat tcctgtacct
    42781 tggatatcgt cgttgaaagt agtgatttga tcttcgtatt tttctaagat cgctgcagca
    42841 tttcctcgtc caaaatcttc ccaatgcaat aacaattctg ggaataattc ggtagctgat
    42901 tgaacgaatt gatcgatgaa ttcatagtaa gtttcgcctt ctacacgagc atgacgattg
    42961 cctaagtata agggattatt caataattct tcattattag taccagcgtc gatcgataca
    43021 ggcaaaactt gtgctggatt aataccagca gcagcagtat agaccatcaa tttgccgata
    43081 gcgatgtcaa caccgttcac accccagtcg cccataccta agattccttc tgcatcagtc
    43141 acaacaatca aacgaatgtc tcgtccatct gccgcgttct tcaaacttgc tttgatgttt
    43201 tctggttcgt cgattgaaag aaatgcagca tcttgcggtt tcaagaaaat ttcgttgtat
    43261 tgttcgattg aatccgcaac gacaggatca taaacgacag gcatgaattc aactaaatgt
    43321 tcgcccatca atttataaaa caatgtccga ttcgtattga atagattcat taagaagata
    43381 cgtttttcca aatctgtttg tttgcttaag tattgaccat aagcttgaac agattgttgt
    43441 tccagtgttt ggacagtact tggaagcata ccagtgattc catattttgc ccgttcttct
    43501 tttgtaaaag ctgttccttt atttagaaaa ggattattta ataagtttaa ccctgtaagc
    43561 atgaatgatt cctcctaagt tttaatacaa acgaagtata gaagtcagat gatgatatag
    43621 tcaaaaagag caggtatgat aaattttatt tatatgtaat atagccaaaa gaaatcaaaa
    43681 tagcagtatt tgttcttttt atatcgacaa tccttgcttg aatactatgc gtatctctta
    43741 tatgctagag aaagaaaagt agaagaataa gggatagatg gaatggataa ataggatttc
    43801 tgaggaaaaa agcacatgat agcgttgata ggagtcacct atgtcaggtg ataaaaatac
    43861 ataagtagaa aattaagagg aggaagagaa aatgaaagaa gttcaattga ttagaaaaag
    43921 cgaactatca gaaggcggtt gcaatgcatg tggcgtagta gaagcgacaa gctatacatt
    43981 aaaattagat tccaatcaag caataatctc tgaactgaca gtaggcggtc ttgtggacag
    44041 tctggcgctt gctgaaggtt ttactggaga agatatttat gagatgtttt cagaagtccg
    44101 tcagttaaaa aaaggagaaa aatgcataga ggttcatcat gagagcccga atgtgaggtt
    44161 caaacgtggt gataatgaga tgatcttcaa gaatcatgtg tctgatcaca ctgaactata
    44221 tgaaatcgtg aatcaaatac tgtctgggat ttttgaatta ggaccttatg agttcaagga
    44281 agaaaacggt aatccaaaat taaatgaaga atggcaagaa acgattgaaa cacaaagaaa
    44341 caatccacac ttatttcaat agtcttccac agtatttcgt aaaaatgttg atgaaaaaga
    44401 aacaccgtga atcagaggtc gtgaaaaacc tgccctgcat caagtaataa gaacagccaa
    44461 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagtttt
    44521 tgaacaccgt ttaaggaaga gactgtgaag tcaacgttct gacctgagta ttagagagac
    44581 aaatggcaaa atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg
    44641 attgaacacc gttttatcga gaggttgtga aaaagtcgct tagtttcgag tagtaagaaa
    44701 aattttgtga aaatggcttt ccacattttt gcataaattt gacttaatac cgagaaaatg
    44761 gcttttgaac accgtttatt caaaaaaagg gactttgaca ctacttttgt caaagtccca
    44821 tcggtttttt atctattttt attacaatca tttcttccag agtagtgaca tctggaatgg
    44881 ctgaaatgta aacagattat ttgcctgtat caatgtcgaa gagtaatata aaaagtgtaa
    44941 acgctatcat attgttcatc attcaaattt tatagagaga aggcattgag atggaaaaaa
    45001 catatcaagc aggtacaaat gaaggaatag tagattttat caatatggaa gatttagaaa
    45061 tcgcggcttc acaagtgatt ccagctggtg gttatggtta catcagcagt ggtgctggcg
    45121 acttatttac ttatcaagaa aatgaacggg cattcaatca tcgtttgatt attcctcatg
    45181 tattaagaga tgtagaatta cccgatacaa ctacacattt tgacgaagaa atgctgactg
    45241 caccaatcat catggcacca gttgctgctc atggattagc tcatgtgaag gcggagaaag
    45301 cttctgcaaa aggtgtagca gattttggga cgatctatac agcaagttct tacgcttctt
    45361 gtactttaga agagataaga gaagcaggcg gggagaaagc accgcaatgg tttcaatttt
    45421 atatgagcaa agataatgga atcaatttgg atattcttga agtggccaag cgtaatggag
    45481 caaaagcaat cgtattgaca gcggatgcaa cagttggcgg aaaccgtgaa acagaccgca
    45541 gaaacgggtt taccttcccg ctgccaatgc cgatcgttca ggcttatcaa tcaggagtag
    45601 gccaaacgat ggatgctgta tataaatctt ccaaacaaaa acttagtcca aaagatgtag
    45661 aatttatcgc tgctcattct gatttgccag tctacgtgaa aggtgttcaa tcagaagaag
    45721 atgtctatcg atcattagaa tctggtgctg gtggaatttg ggtatctaac catggtggcc
    45781 gtcaattaga tggggggcct gctgcgtttg attcgttgca atatgtggca gaagcagtag
    45841 ataaacgtgt accaatcgtg tttgacagcg gtgtacgacg tggacaacat gttttcaaag
    45901 caatcgcatc aggtgccgat cttgttgcta ttggcagacc cgttatttat ggattgtctt
    45961 taggaggaag tacaggagtc catcaagtgt ttgatttctt taaaacagaa ttggaaatgg
    46021 tcatgcaatt agctggaaca caaacagtag aagatatcaa aaaaataaaa ttgcgtgaga
    46081 atcgttttat ttaagaaata aatgacgaaa aaaataggag tgcggcagat gatgccgtac
    46141 tcctattttt atagttcaag gatgtcacta atagaataat ttgaaacgaa aaaataaaat
    46201 tgaaatattt tttcatactt aataaaaaag gaagaatatt catgtaaacg attttattgt
    46261 ttttttctct tttatacaaa aagggtcata atttcaagta agcggatgaa ttcatgagga
    46321 ttttttgcat actgtctcta ctatacttag gtcactaaga aaaaggagtg atttattatg
    46381 aaaaagaaca tgattgggac attattactt tcaacacttc ttctaggcgg cttggcaaca
    46441 ccagcttttg ctgagggtca agcgacttca aaaggagata ttacctttac tgaaccaaca
    46501 aataccgttg agcctcttaa ccctactgat ccttcaaaac cagtagagcc agcagatccg
    46561 gaaaatccag caactggcca gacaggttct ttaacattgg atgtagttcc tgaattgcca
    46621 tttggtacac acgagattga aagcggaaca aaaacgtatc aagtagacgc ttcaaaaaac
    46681 gatacacctt atctccaagt atcagatcgt cgaggtgtag gtgcagatgg ccaagcacaa
    46741 gggtggaacg tgacagtttc ggtttcagat tttgtaaacg gttcacaagt tttgcaaggc
    46801 gctgaattag attttggaac atccactgtt aaaagtacgt cagataacga atccactgga
    46861 ccaactagtc aaactgtaac tgggttgagt aaagcaagtg cagcgacacc aatatttaca
    46921 gcagcaaaag atcaaggtct gggaacatgg ctttctgttt atgatccagc aaatatcaca
    46981 ctgaaagtgc cgaaagcagc agctggaaca ttcacggctg atttgacttg gaacctcgtg
    47041 gctggcccag tagcatagag tatgaaataa attcaacaaa ctgcggtgaa aatactatag
    47101 gtgaaggatt ttttaccgca gttgttgttg aaaggatgtg gtggacaatg aatcaaagta
    47161 aacgactgtt tgtttcgttt ttttctattt taagtctatt tttcattttt ccgtcaatca
    47221 gccaagcaaa ggattcagca ggagactttg gaatcaaacc ggtatttcca gagaaccaaa
    47281 tagataaagc aatcggttat tttgatttat tagtggcacc ggaacaaaat cagacactag
    47341 aagtaattat cagcaattct tcagatgaag aacgaacatt tgaggtctct gtcaatccgg
    47401 cggtaacgag tgatggtgga acgatcgatt atagtcaaaa aaacccaacg ttagatgaga
    47461 cattgccgtt tgatgtccgt gacgttttgc tcattgcgaa aaaggaaatc aatgtatcag
    47521 cacatgcaga aacaactata cctatagaag tgaaaatccc agcaaaaagc tttaagggac
    47581 gtgtattagc gggtattcat gtttcaccta aagaagaagc tgaaacagaa aatgctacag
    47641 aaggagcaca aatcaaaaat cgtattgctt ataatctcgc agtcgtttta caagaaagtc
    47701 aagagacgat agaaccggat ctgaaacttt tatcaggaga tttggacgag gtcaacgcaa
    47761 agccaactgt tcagcttcgt ttccaaaatc ctcagcctag gattatcagc aatttgatat
    47821 ttacgagcaa gatcttttat gaaaatcagc tttatattga aaatacgtct aatgaatttt
    47881 tagttgcacc aaattcgaat tttcacttga atcttgattt agctggtgat aaagcaaaag
    47941 ccggcgatta ccgcgcagaa atcatagcaa aatcaggcga cagtaatgaa tggcgattta
    48001 cacaaaactt tacgatcaaa aaagaaaaag cacaaaaagt aaatgaaaat tccgtttttg
    48061 cagtacaaga acaatctttc ccatggcttt atgcaggatt ggttgctgca gttctagtgt
    48121 tatggttgat tttgctgttt ttgtgggtcc acaagaaaaa gaaaaaagga gaaacaacat
    48181 gatgaggtga tttcgttgaa aacatcgatc ttattgggag ggattattgc aagtttgctg
    48241 ttcttcagct ggcaagagcc agtccaagca gataccaaaa gttcaggtac gattacattt
    48301 tatgatctaa gtccagttcc gcatccaagt ggttcagtca atggcgcatc aaaacagcag
    48361 acacagctac cgatttataa agaatctaat caacatggcg tattcccgga gacgaatgaa
    48421 gaaaagatcc gttttcttta tttgatcatt ggtatagaat tatggcttct tgcgtggttg
    48481 ttgttatgga gaagaaagga aaaggaggat gaacatgttg ctacaaaata aattttcatt
    48541 ttttcgctcc ttctttttta cttcgctttt tgttttaagt atatttatct tttcaccttc
    48601 ggcagaagct gttggagcaa cgcctcctgc catttcttat gatccataca cgtatgaaaa
    48661 tatcgtacct ccaaatggtg gacgtagtgc agtcaatggc gggaagcttg tccaactaac
    48721 tggggctaac caattgccta aattgactgc tacttatttg aacgatggtt caaatgatcc
    48781 ttggaaaggt ggcacggtcc gttttcattg ggaaagccat gtgaaactaa caaatgtact
    48841 tgatttggtg aatatcactg cacaaggatt tgcatttgtg gcgatcatca atttgccgga
    48901 acatgtatca agcagtgatg tattaaaagc aattgactgg aacaacgcct acttgtatat
    48961 tgccggtgcc cccatcaagg ttactagcgg tagtttatta tcagcaggaa gccatacctt
    49021 gcgttttggg atggggtcgt gggatacaaa tactctattg gcagatatta ttgctattat
    49081 tacgcgaggc gaattcaacg tggacgatat cccgcttcaa tttgatgtta cagctaatgt
    49141 cgcgaagatg acagaaaacg gagataaata tgatacgagt ccaaacaaaa ttttgaccaa
    49201 gggtaaatta caaccttcta tgtctaaaaa ggccgttttt tctgttgatt tttatgattc
    49261 gaataatatt atccaagatc gtatgttcaa ttcgatttta gctccagctg caggtagatt
    49321 ttatcctaaa ttaactggcg gaaacttgaa tccaggagca tatgcatttt ctgcaagtgc
    49381 agagataaat acgtggaata gttacatctc aacaagtgat tcaacaggaa aatataatac
    49441 atttgctgat accacagaat acgtggatgg aaataaccag aaccttccag gctctaccaa
    49501 tagtcggaca ttgacgatgg ggctgactga aggacgtttt gatcagttgc catttagtcg
    49561 ctttgatcgc gtagtcaact attttacagg aaaaaacgtt acacaaggag caatactgac
    49621 tcatactcca gcaagcacaa gtggattgaa tcagacagcc aatatcgtgt acagtgggaa
    49681 agatgcgcaa ggcggattgc tttctcctgt tgctttaaag gtattggagc agtacaagct
    49741 agacggaacg gttttaccaa caaacttaac agccgatagt cagtggggaa agctcctttc
    49801 ttctgcatcg taccaagtca cggccaattg gtcagcaact gaactaaaaa agggttcgat
    49861 ccattacagg ctttattcga aaggaaccca aaaattagcg acaggatgga cagatcaact
    49921 tttccaaacg atccaatcaa ataacggggg tgtaaataca gctacttcta cactacctgc
    49981 attggcttca gggcaatatt attttgatta tcgcttggtg gacgatgtac ttactaacat
    50041 gtatccgtct tttgcgtaca aatggcagtc tgaacaagct ggaatcacca ctcttcctca
    50101 aataacagtg gctaattttc catctgtgag tgcagatagt cagctaaaaa accttagcag
    50161 acaacctgag acaggagatc ccctgtctgc tctatcagga gatacgattc aagaaaatgt
    50221 gacattcacg ttaacaaaat ctggggatgc gataaccgac aaaaaaatca cgatctcact
    50281 tcctgaaaat actacttata tcaatggttc cttaaaatta aatggtacaa ctatcgcaga
    50341 taccggcatt caacaaggag tttctgtccc agcagatcta ttgagcaaaa taggagatac
    50401 cattcatctt acttacaact atcaattaaa tactgtagat acttctgtac aatccgtcag
    50461 catactgaca aaggcagctg tactttccag caatattaca ttagcagatg gtgctaagct
    50521 tcctaaccca gttgtccaaa catctgctaa aacaattctt gtccccaaac aagaattaac
    50581 attagttaat gtaccagatg attttacatt tggtaacgat ctccccaaac cgttgaagac
    50641 aagttattat gaagcaaaag gcgatttttc ttttgatgtg cgggatactc ggcttccaag
    50701 cacgtctcct tggcaactga cagggacatt gacttcttta tttaagaatg atcaaggtca
    50761 agaattaagc ggaacaaaat tatacttcaa tcattctgga tcaaaacaat tgattcagca
    50821 aggtcaaaac acgttgattt atgagagtga tggaacagct aaaggagagg ttctcgttga
    50881 ctttcccgat accgatggtt tactcttaga ggtaaatagc agtacgaatg ctcaacctgg
    50941 cgcaacgtat caaggcatgg tcacatggga actgacagct gggccaacca gctaagtgat
    51001 tagaatttgt atggatctgt gataactgtc acagatcctc tttttcaagg atgagaagga
    51061 aacttctgct gttaaaatca gaaatgcttg gaggagtgga cttggaactt ttcagtttgc
    51121 ttgaaaaaaa tgaacaacgg caaatcaaac ttttccaact tttattagag gaaaaaggag
    51181 agatttccgt taataacgta cttacccgct tatcagttga tcgggctacc ttgaaagaag
    51241 atctgtttta tttacaagct aacttggaaa atatcaaaca attggaaatt gttatccaag
    51301 aagggaatat tttattaatc agacatggaa atatagcagc agtcgatgtt tattatcatt
    51361 gctacttgcg ctattctaca aaatatcaga tacttcttta tctgttggaa aatggctcat
    51421 ttgatcggca gaaacttgtc atggaactta atatcagttc ggctactttg tctcgcagag
    51481 tgaaggaatt aaatgattct ttaaatgagt ttcatctgaa aataaaaagc gggcggctga
    51541 ccggtccaga aagtcaaatt tgttattttt atttccaatt attttggttt ggacgtcctt
    51601 atcttgaaaa caaaaaagaa tacagtgatt tatcaggaaa cactttttta gatctgctgc
    51661 aaaaagagtt tagttttact attacagaag aaggacgatt gaaatttgaa atatggcttt
    51721 ccattatgaa gaagcgaatg cgctgtacga aaaaatccaa accagattat agcaatcttc
    51781 ctgttggatt gtttcaaacg acacaatttt tattggacct ccatacattt ttgacccgtt
    51841 acttctttca atatgccttt ccttggaatc aaaatgaaac gttggttttt tatcttttca
    51901 tgatcagtaa ctttacatta gatacacata actcgcatgt ccaggagttt ttgataagcg
    51961 aaaaatacaa agacgacgta gtagctcaat tgaatcgaac gtttaaacaa tcgatagaag
    52021 aatatttctc tttttatgtt tttccagaag agatttcgca aaagattgcg ttgacagtga
    52081 tgcaaaatca cgctcatttt gcctatttta gaggatggat gaatattttt ggccaagaag
    52141 gattaaaaca gcggttaact gaagtagaag ataaacaatt cctggtttta tgtgaaagat
    52201 tggtcagaca aacatttgct attgttgatt ttactgaagt agacgaggaa aatgcccgct
    52261 ttgaattatt tgctcgctat gcatctattt tgcggacgct gatcaagcag ttagaattac
    52321 gtctgcaaat tgcttatgat cttccttatg aaaggctaat ggcggatatc gtgaaagaaa
    52381 tcatccagga acaattgctg aatacgatca aatatgattt agtcgaatac gagaaagaaa
    52441 agcagtatga tatcattttg actagccaat tgaaagagta cccgtcacag aagtccgcta
    52501 aagtttttgt attcactagc aacgaatata attatgattt cccctatttg aaccaatttt
    52561 taaaagaatg ttatttagaa aaattgaatt taaggatgaa taaaacatga aaatcgtgat
    52621 cattggtgct tcccatgcag gcatcacagc tgccctaaat ctaagaaaac ttcaaccgaa
    52681 agcagaagtt ttactgatcg atgaagatca taaagatgga ctaggctatg tttcaaatgg
    52741 aatcaacctt tatttaaaag gaaagatacg tagtttagct gaagttgccc ataacatgcg
    52801 gactcttcaa gaaagtgggg caaaactgat caccgaatgg agagtaactg aacttgatcc
    52861 agacaaacat cagctcatcc tcgcatccaa agaaggaaaa aacgagacca taacctatga
    52921 taaattaatc gtagcaacag gttcctctcc tgtcaccttg tataaacaaa ttgaagctga
    52981 aaatgtctac acctataaaa atctagtgca atctaagcaa gtacttgccg ctttaaaaga
    53041 agcaaaagaa gtagtgatct tcggtgctgg ttatattgga ttggaattag cagatgcttt
    53101 gagaaataaa ggatacatta ttcatctagt tgattatatg ccgaatgttt tatcaagata
    53161 tttcgataag gatatgatca acagttttca aaatcagctg caaactaagc aaatcaattt
    53221 ttatccaaat gaattcttga tcgattggaa aaaatcagaa gagaaagtag tatccgtaca
    53281 acttctatct caagcaataa aggcagatat ggtcattttt tctgcccaaa ctcgtcctaa
    53341 tacgacattg ttaaaagaaa aagtggcttt gtatgaggat gagactgtga tagtcaatga
    53401 atatctgcag acaagtgatc cggacatcta tgcgattgga gatatcgtcc cagtcagttt
    53461 tgacaaaaat aaacggcatc tctttttacc tttagttact cgagctgtac atatggcaag
    53521 agcagtagcg ctaactttga gtggtcagcc aaccgcttac gacctcagac aaaagataac
    53581 agcagcagtc attatagact actttttagg aactgtaggg ctgacagaag atgaagcgcc
    53641 attcttggaa caaaataccg gttcgtgttc aggagaattt gatctatttc cacaatacga
    53701 tgaagaaaac aaaacagtaa atgcaaagct gatctaccat ccggatacat tagaaataat
    53761 tggcggacag ctgataagcc aagaattctt attatcagat ttgaacctgc ttgcggatat
    53821 cgtgaaacac aaaactacga ttccacagct agcagttgag gattttggat ttctgtctga
    53881 acacacctct cgttttcact acctcaatga gttagctttt aaagtactag ctaagagagc
    53941 aaatagcaat agagtagata aaagactgtg agaaatatca cggtctttta ttgtgtgggg
    54001 atataataaa tattaatcaa tcgagaataa aaaattcata taatgaaata gcggaagaat
    54061 tttttgagca taatattcgc caaaaattta tcaagtgata aaattgttgt ataaaatgat
    54121 tatttcagga ggaggagtta aatgttttta gcattaaatg aaattatgca ttcaaagtta
    54181 cgttatgcgt tagttgcagg ggtgatgttt ttgatcgcct acctggtatt ttttttgact
    54241 gggttagctt atggcttagc tcaagataat cgaacagcag tcgacaagtg ggaggcagat
    54301 tcgattgtgc tttcgaaaga tgcaaattca aatctaggga tgtccatgat tactaagaag
    54361 atagcagaag aagtcgaagg tgggaaagtg gcgtatcttg cccagacacc tggagtcgtg
    54421 actagtaaag acagtacaga agaaggaaaa atcaatgtta gcttcttcgg tatcgataaa
    54481 aatcaattca tcatgcccaa tcttgttgaa ggaaaagctt ttgataacga tgatgaggca
    54541 gtaggcgata ttagtttgaa agaagaatat ggtctagccg taggagatac agttaagtta
    54601 tctggtagtg acaagacgtt taaactaact ggctttacgg atcatgccaa attcaatgtc
    54661 tcaccagttc tctatacaac catcaatgct taccaagaga tccgcttcga aaaagaagat
    54721 acaagtgaaa atgcacggat taacgcaata gttgtcagag gtaaaatcag taatttacct
    54781 gaagatttag aacagatcaa aatttctaaa ttcatcaatg aattacctgg atataatgcg
    54841 caagtattga cttttggatt tatgatcgga tttttgatcg ttattgcggc tattgtgatc
    54901 gggattttca tttatgtact gacgatgcaa aagattaata tctttggtgt aatgaaagca
    54961 caagggatca caggaggatt tattgcgcgt tctgtagtgg cacaaacatt cattttatca
    55021 tttgttggta ttcttcttgg tctattagga acagtgggaa catcccttgt tctacctgat
    55081 gcggttccat tccaaagcaa ttggctgttt tttggcgtca ttagcttgtt gatgctggta
    55141 gtagctgtgt taggcgcact attttctgtt cggacaatcg taaaaatcga tccgttgaag
    55201 gcaattggat aagaaggagg aagagcatga aagcaataga atttaaagaa gtagaaaaaa
    55261 gtttccaaga tggcgaccaa gtagttaaag cattgaaaga aacaaccatg agtatcgata
    55321 aaggggaatt tgttgcaatc atcggtcctt ctggttcagg taaaagtact tttttgactt
    55381 tggcaggcgg attgcagacg cctagcagtg gctctgtatt tatcaatgat caagaattca
    55441 gtaatcaaaa agaaagtgaa cgcgttaaac tacgttttaa agaaattggc tttattttgc
    55501 aagcttccaa tctggttcct tttctgacag taaaaaagca gttattatta gtagataaga
    55561 tcaaacatga acatcgtcaa aaagaagcaa aagaattatt tgagcagctt ggcgtggata
    55621 agttgatcaa caagtatcca gaagaactat ctggtggaga acggcaaagg gtcgcaatcg
    55681 ctcgtgcatt gtacaatgat ccgtccatta ttctagcaga tgaaccaact gctagtttgg
    55741 attcagaaaa ggcacgagaa gtagtcgata tcttggcaaa agaatcaaaa gacaaaaata
    55801 aagcaacgat catggttact cacgatacac ggctgattga caaatgcgat agaatattta
    55861 tgatggaaga tggtgtattg aaagaaaaag aataaccaaa aagcaggtgg aaaaatggtc
    55921 catcgataca acaaagatac acagcaaaaa attttgaaag aagcgactga cttgtttatg
    55981 tccaagggat atctcggcac ttcaacaaga gagatcgcac aaaaagttgg gatcacccaa
    56041 cccaatctct atcattattt cggtgataaa gaaaaactat atacggcagt tttagaaaac
    56101 cacttaaaag atgttggaaa agctttgaga gaaatcgttc aaacaagcga aacgggattt
    56161 caagtaacct tgacaaaaat ggcgcagttt ttgattgaga cacatctggt cgatttgttt
    56221 ctgatgcttc acgatcttga aagcaatctt tcaaaggaaa caagagatca tcttttcttt
    56281 ctatggaaga aaaattatcg tgaacctttt gaagaaatct tttcagcaaa ccaatctgtg
    56341 ctaagaaatg ggatttcaaa agaaatcgca gcaaggcatt ttttcttagt gttagcacct
    56401 tacatcactc ggtcgaaaag acctgtggaa gaaccgctaa atgtggcgca attgatcgat
    56461 ttatatttga atggtgtatt aggagaagcg taaagctgtt atatagggag aaaaatagtt
    56521 aggtgaagaa gcaagatatg acgaagatcg ttatatcttg ttttttttat ataggtagtt
    56581 tttcataaat acaaatttgt tattctctca tgattatcag ggtatatttt tatttattat
    56641 gtcggtgttc caggaagtgt tttaatttaa taacgaagaa attaattgtt tgtagaatga
    56701 aggaaactat ttattgggta gatgaatcac cacgaatagt caaaaggaga tttcaggata
    56761 tgccaaaaat gaaaaaaatc attttagcag taatgttatt ttctacggtt atatctttta
    56821 cagccccttt tttgcgtact taagctgatt ttaagttttg acccttagtc tggatctacg
    56881 aggtgagagt caagaatgaa aaaaataatt ggagcttttg tatttgcaat cattatcatt
    56941 attatctgtt ttcaaataga tgtttttggt caaaaaaaga tagttggaca aacggtcagc
    57001 agtacgaaca gtacggttac aaagacaaag gaatcatttg atgatacaga acaagagaca
    57061 ttaatcaaaa tcggaaaaaa tgaccgtaca ctatatacag atgactcgct aactacccca
    57121 cttgcaacta taaacggcgg agagctggcg gagtttcttt ctgaaacaaa aaatgcttat
    57181 cagatcaaga caaatgatgg ctatactgga tatttagccc tcgaagatgg aaccaaagtc
    57241 acaaagaata tacaaacaaa accggaagag ctatctgatg cagtgattgt attagatcct
    57301 gggcatggcg gaaatgatac tggggcatta agcaatgatg aacaaacaga agaaaaagat
    57361 ataacattaa gtacagccat aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt
    57421 tatttgaccc atactacaga tgaattagta cagcttggag atatatgcga ctacagtgaa
    57481 gaaaaaaagg cagatgtctt tatcagttta cacgcagact ctacggaata tgcgaatgaa
    57541 gcaactggaa tcacgacata ttattactat ggacaagagg aaacattagc acagacaatt
    57601 gctgactcct tcactgatct gcctctggat tcaagaggaa tctccactgg gaactatcaa
    57661 gttcttcgag aaaatcttca accttctatt ttaatcgaga tgggttatat gaataatgat
    57721 agtgatttaa aggaattagt aacagacagt tatcagcagc agattgctgc aagtttgaca
    57781 caagcattga ccacttattt tcagtaataa ataagcccag ccaaacaaaa atagctcctc
    57841 atatttttcg tttggccggg cttattatcg cagatgcaag cttttgaaca ccgtttaagg
    57901 aagaggttgt gagcctgccg tttaactccg cgtcacaagg agcaatttca aaaaacagct
    57961 tctcatgttt gatgactatt gtgacttgtg accgaggagt tggcatgaga acaccgttta
    58021 ttcggaacaa gggactgtga catgactttt gtcacagttc cattattttt ttagcagctt
    58081 caaagctttt tctgtattgg caaaatgaag tttggcatat ttttcaagca taggcatgcc
    58141 gcctttctcc aatagttttg ccgctacttg gtcagatttc gttccagctc ctgatggaag
    58201 ggtgattcca gcttcagctg atgctttgtg taactcttcc aaaaagctgg cacgactgat
    58261 gatagaagca gcagcaacag ctaaatgata ttgttctcct ttagtaacga agtacagttt
    58321 ttcttgtaat tgattttttt ctaaacgcgc atatttttta aaatttgctt ccggcgtaaa
    58381 ctgatcgatc aaaatcgctt ctggtttttc tggctcgatt ttttttagca gcaaatggat
    58441 cgcttgattg tgcaaagcga ctttcatccg aacggcattg tattttggtt ggatctcatt
    58501 gtatttttct ggagataaga caagcagttt ataggggatg gtttttttta agatgtcagc
    58561 aagctggatg atttggctat cttttaactc ttttgaatct ctaacaccaa gtttacgtaa
    58621 ttctgcaagc tgatcacgtt tcacataagc agcacatact gttagcggac caaaatagct
    58681 gccatttccg acctcatcac tacctaaaac ggataattga ctgatatttt ttggcaaaga
    58741 agaggctgtt tttgctggct tggcttgttt atcctgtgcc tccccccatt tatcagcttc
    58801 tattgctgca ttcgtacctt gaaacatcac ttttccggat gtataagcgg taatggtcgt
    58861 cccgtctttt tttgcagcaa agctagtata aggaatctgt ttatttaaca aataagagcg
    58921 atagtatgct ttcatttgac taagttggtc gtttgttgct ttgataatga cgttgctcat
    58981 aaaattctcc tcgtttttat acataaaact ataccgcaac tcacgacttt tcgttttcta
    59041 agagattgcg agacatagca tttttttaaa gtttatcata taatagttaa gtatgtgaaa
    59101 aatatttgtg gagaacggtg aaagaaccaa cttcatggta cactaaataa aactttcatc
    59161 aaataggagg aaatgattcg tatggcgcac gaaaaaacac gctacaaagc agtgattgcc
    59221 aaccaaacat atactattat cggacgggaa accaagcatc atatggatat cgtaacgaag
    59281 ctgatcaatg aacagttagc agaattgaaa caattatcac cacaaatgga taatgaacaa
    59341 gcagcaatct tgatggctgt caatgcgctt tcggatcaat tgaagaaaca agaaagaatc
    59401 ttggagctgg aagaagaaac agcagaatta aagaaaaaaa tgatcaaatt tacagagctt
    59461 gaaaatcgtg tgaaacgcat tgaagcaatc gagaacgaag ctcgggaagt attgaaagaa
    59521 aatggtcaag cagatcatac cattaaaaat catgtggaag cacaacagat tttaaacgag
    59581 aaacgaaaag gacaaattaa acaaaaatct tctaattaag atccttttat caaaataaga
    59641 aaaatttaaa aaagttagaa gagaaaggaa cgtagcatgc tgagtttgct gattttattt
    59701 ttattgctaa ttgcgttttt ttctggagca cgtcgcgggt ttgctttgca aatcatattc
    59761 gcgattggat atgtattgtc atttattgct gcccagcatt tttacaaacc attagcaagt
    59821 catttggaat tatacattcc atacccagct gtcaccccaa catcaaagtt agcatttttt
    59881 gatcaggtat ttgcttttca cctagatgaa gctttttatg caggaactgc ttttctgatt
    59941 attttgctaa ttggctggct gcttacccga tttgtggggg tttttgtcca tggattgacg
    60001 tatgtgccga tcttgagaca ggtagactgg attgcaggag gcatcctgtc actaatcatg
    60061 gcttacgtta ctatattttt gattttgcag ttacttgcct ttgttccatt agtgtggtcc
    60121 aaaatcaatt cggcgagcat agtttcgctc gttttatcgt tgagagaacg ccatttctta
    60181 ccaacaagat gtatgagctt tgggtaacga atattttgaa ttaaggaaaa tagtgctgga
    60241 aaatatttcg ttttttgtac agagtagttt atttaagaag gctgcgtagc gtatgtccgg
    60301 cacagctctt ttttcatagt gaaagataag gtgataaaat gaataaccga atccttgaaa
    60361 cattggaatt tgaaaaagtc aaacagatgg tcagacaatt tgtagtgact gcacaaggaa
    60421 aagaagaact ggcagaattg gtaccagtga gtgagaaaca aacgatcaca aactggcttc
    60481 aagaaactga ggatggattg aaagtgcaac gtctgcgagg cgggatccct atacctaaac
    60541 ttgaaaatat ccgtccccat atgaaacgga tcgagatcgg agcagacttg aatggagtgg
    60601 agcttgcaca agtttccaga gtattgtcta cgacaagcga attgaatcgt ttcattgatg
    60661 atctttctga cagtgaaatc gaatttgcac gtttgtatat gtgggcagat cagttagtca
    60721 cgatccctgt tttgagccgc cgtttaaagg aagcaatcga tgaagacgga cgcgtgactg
    60781 atgacgcttc tcctgagtta aagagcataa gacagaacat tcggcgaagt gaacaagctg
    60841 ttcgtgaaca gttagatggg atcgtccgtg ggaaaaatgc aaagtattta agtgatgcga
    60901 tcatcaccat gcgaaatgac cgctacgtta tcccagtcaa acaagaatac cgcggtgtat
    60961 ttggcggtgt agtccacgat caaagtgctt caggacagac tttatttatt gaaccaaaac
    61021 aagtggtgga tttgaataat cgtttgcgtc aataccaaat cgctgaacga aatgagattc
    61081 aacgtatttt aagtgaactt tctgctgaac ttgttcccca tcgtcaagaa atcatccaca
    61141 atgcttatgt gattggtaaa atggatctga tgaatgcaaa agcacgattt ggtaaagaag
    61201 taaaagccat cgtgccggga atcagtgaag acaatcatgt cgtcttgaaa caagcaagac
    61261 atccactgat cgatcaggaa aaagtagttt ctaatgacat cacaatcgga aaagactatc
    61321 aagccatcgt cattacagga cctaacacag gtgggaaaac gatcacgttg aagactttag
    61381 gtctgttaca actgatgggg caagcaggat taccgattcc tgcaggtgaa gaaagtcaaa
    61441 tcggtatttt tgaggaagta tttgcggata taggagacga acagtcgatt gagcaaagtc
    61501 tatcgacctt ttcttctcat atgacgaaca ctgtagatat tttatcaaaa gtcaatgaaa
    61561 aaagtctggt attatttgac gagctcggtg caggaacaga tccgcaagaa ggtgctgctc
    61621 tagcaatcgc aatcttagat gatcttggta aaaagtctgc ttatgtgatg gcaacaacgc
    61681 attatcctga attgaaagtt tatggataca atcgggcaaa tacgattaat gccagcatgg
    61741 agttcgatgt ggatacacta agtccaacgt atcgtttgct gattggcgtt cctggacgaa
    61801 gcaatgcgtt tgaaatctct agccgattag gtcttgatac agaagttatt gatgaagcga
    61861 agcagttgat gaatgatgag agccaagatt taaacgaaat gatcacagat ttagagaatc
    61921 gccggaaaat ggcagagacc gaatatctgg aaatgcgtca ttttgtttct gaggcacaag
    61981 aacttcacga tgatttgaaa gaagcttaca gctatttctt tgaagaacgt gaaaaagaaa
    62041 tggaaaaagc aaagaaaaaa gcaaacgaag tcgtgtcaga ggcggaagaa aaagcagaaa
    62101 aaatcattgc tgatattcgt aaaatgcaac agcagattgg gcaaggaaat gtgaaagagc
    62161 atcagttgat cgatgcaaag acccaattag caaatctaca tcaagaagaa actttgaaga
    62221 aaaataaagt attgaagaag gcgaaagaac aaaaaacgtt gaaaccggga gacgaagtgt
    62281 tggttacgac ttacggccaa agagggacgc ttttacgtaa aaacgggaat cagtggcaag
    62341 tagaaatcgg tatattaaaa atgaatgtgt ccgaagacga gctgacgcct gttgctcctc
    62401 aaaaagagcc gacacaacga gttatccatg ctgtacgatc tgaatctagt agtcacgtgc
    62461 cgaatcaatt ggaccttcga ggaaaacgat acgaagaagc gctaagtgag gtagatcaat
    62521 atttggattc tgccattcta gctggttatc ctcaagtgac tattgtccac ggaaaaggaa
    62581 caggcgcact tcgcaaggga attactgatt atcttaaaaa ccatcggagc gtcaaaagct
    62641 ttgagtttgc accggcaaac caaggcggaa atggtgcgac aattgttaaa tttaagtaaa
    62701 gcttactaaa ggtaagcaga tggttcgcta tccaagtata gaaatgctat actaatcata
    62761 gattttaaaa atggaggtct ttgatatgtc acaagtaatt acagataaga catttaatga
    62821 agaaacagat aaaggacttg tattgattga tttttgggca acttggtgtg gtccatgtcg
    62881 tatgcaagca ccgattttgg atcagttgga acaagaatat gatgaagaag aattcagaat
    62941 tgctaaaatg gatgtggatg aaaatccaga aactcctcaa caattcggta tcatgagcat
    63001 tccaacatta atgttgaaaa aagatggtca agtagtagaa aaagctgttg gtgttcattc
    63061 aaaagaacaa ctacgtcaaa tgatcgatca atatttataa aaacttacag caaaaataag
    63121 ctgagggtgg gactgaatcc agttccgtcc tcggtttttt tgcggttgag ttaaggttat
    63181 tcaaattaat attttttgag tataattacg ttgtcaggct ggattgtttt tttgacagac
    63241 atgctataat aactttaatt gaatatgaag gggagtacca gatgaacgaa cgaatcaaaa
    63301 acaaattagc tttacttcct gatcagcccg gctgttactt gatgaaagat aaaaatggaa
    63361 cgatcattta tgtcggcaaa gccaaaatat taaaaaatcg tgtccgctca tattttactg
    63421 gcagccataa tacgaaaacg gaacggcttg ttagtgaaat cgaagacttt gaatacatcg
    63481 ttacagaatc gaatatcgaa gcattgctct tagagatcaa tctgataaag aaaaatgatc
    63541 ctaaatacaa cattatgtta aaggatgata aaacctatcc tttccttaag ataacgaatg
    63601 aaaaatatcc ccgtttggtg attactcgta aagtactaaa agacaaagca ctgtattttg
    63661 gaccatatcc cgatgtcggt gcggcgaatg agacaaagaa gatcctcgat cgattatttc
    63721 ctctgagaaa atgcaaacct agtcagacga aggagccttg tctttactat catttgggac
    63781 aatgtctgtg tccttattat ttcgacgtag atccgaaagt ctatacgaaa atcgttgatg
    63841 aagtgaaaaa gtttttaaac ggaggacacg aaaaaatcga gtcagagatc catcagaaaa
    63901 tggaaaaagc tgctgaaaac atggagtttg aaaaagctgc agaataccga gaccagatcc
    63961 gtgccattga gacaatcatg actcgccaaa aaatgacaaa tactgattta ctggatcgag
    64021 atgtatttgg ttatgcgatt gacaaaggat ggatgtgtgt ccaagtgttt ttcgtaagac
    64081 aaggaaagct aattgaacga gatgtttcaa tgtttccttt ctataacgaa gcagaagaag
    64141 atttcttgac ttacctcggt cagttttatc aggaaaatga gcatttcatt cctaaagaag
    64201 tcttgattcc tgatacgatc gacaagccca gtgtagaagc tttgttagct acgaaagtgc
    64261 tgcaaccaaa acgaggagaa aagaaaaaat tagttgaatt ggcgaataag aatgcctcag
    64321 ttgctttgaa tgaacggttt gatctgattg ccagaaaaca ggaacggacg atcggagcag
    64381 ttgaacgttt aggaaacgcg atgaatatcc cgaccccaat acgtatcgag tcttttgata
    64441 actctaatat catggggacg aatcctgtgg ctgcgatggt cgtattcatt gatggaaaac
    64501 cggcaagaaa agaatatcgg aaatataaaa taaaaacagt caacggaccg gatgattatg
    64561 catcaatgag agaagtcatc tatcgcagat attcacgagt gattcgcgaa gggttgcctt
    64621 tacctgattt gatcttgatc gatggaggaa aaggacaagt agatgtggca aaagatgtct
    64681 tagaaaatca attaggaatc gatattccta ttgctggcat ggcaaaaaac gataaacata
    64741 aaacaaatga gttgctattc ggtatagatt tggctgtagt accgcttgag cgaaattcac
    64801 cagagttttt cttactccag cgaatccaag atgaagtcca tcgattcgca atcactttcc
    64861 atcggcagct acgcagtaaa aacagttttg cttcccgatt agatgaaatt gaaaggttag
    64921 gaccaaaacg aaaaaaaatg ctgcttaaag agttcaaatc gttgaaaaat atcacagcag
    64981 ccacgacaga agaattacaa gaaatcggac tgccgaaaaa tgtcgcacaa aacgtatttg
    65041 ataaattaca tcaggaatga ggaaagggca ctttacaaag aaagtaaagt gtcctatcat
    65101 tttatgtaca acaaaaagag cgtttacgtt ttgttggtaa ataataaatc gcttacgtct
    65161 ggtgtctaag gatatatgtg atttcttgaa gaaggagtga agaaatgtta gaagtcaagg
    65221 atcttgttaa aacttttggg aactacacag ctgtcgatca tgtctctttc caaatccccg
    65281 atggaaaaat catggggcta attggccaaa acggggctgg gaagacaacg acttttcgtt
    65341 tgatcttgga ttttttgaca caagaccaag gagaagtgtt atggaatggc catcatcttg
    65401 gggagaaaga ttatgatgtc atcggttatc ttccggagga acggggactt tatccgaaag
    65461 taacgattca agaccaactg ctttattttg cagaacttag agggaaatca agaaaagaga
    65521 ttgaaccaaa aatcgatttt tggatggaaa aatttcaggt aaaagggaaa aagacggata
    65581 aagtaaaatc tttgtctaaa ggaaatcagc aaaaagtcca gctgatcgcc acgttaatcc
    65641 atgaacctaa attgatcatt ttggatgagc cattcagcgg gttagatccg gtaaatgctg
    65701 aattgctaaa agatggaata ttggaattga aaaaacatgg ttcatgtgtc attttttcta
    65761 gccacaatat ggataatgta gaaaaaatct gcgatcattt gatcatgttg cgaaacggaa
    65821 aaatggtttt gaatggaaaa gtacatgaga ttcgtgaatc atttggccgt acgaagttat
    65881 tcttggaatc tggtttaagc caacaggaag tagaagaaat cgaaggcgtg aaaaaagtga
    65941 tccttcatga agacaatacg ttagagatta ccttagaaga tcctgaagct gggaaagaaa
    66001 tctttactcg tgcgactcag ttcggctaca ttcctatgtt taaccagcaa ccgccaactt
    66061 tggaagagat tttcaaattg aaagcaggtg aaatcgatgc gtaagttttg gattattacc
    66121 aaagatgtct atttaaaaaa tgttaagtcg atttctttct tgatcatgat attagtccct
    66181 tttatcatgc tgggtatcat ttatgtagca ggaaactttg ctcaacaaaa tagtgatgtc
    66241 aataaaatcg gcgtattggc tgataatgag caaatcagtc agcaaatgag ccaagtcaaa
    66301 acagatgatt ttgagttcaa agcagttgat tctgaagaaa aagcacaaaa agagctttcg
    66361 gaagaaaaaa tcgatgcgta tttagtagtc tcaactgaga atgataagat aaatgggatg
    66421 ctttatagcg aaaattcatt aggacaaagt acacaactac tgatacaaca acaactgact
    66481 ggcttgcaat cgatgcttcg agcaagtcaa ttaggcattt caccagaaga agtagctagc
    66541 ttgagccaac aagcaagttt gactcgacaa aaagtcaatt ttgattcaaa aggaaaaatg
    66601 acagttggag aagataactc gacagtccaa tatgtcgtaa gttatgtagc aacgattgtc
    66661 ttgttcatta ttattttgac gtatgcgcag atcattgcac aagagatcgc ttctgaaaaa
    66721 ggcacgcgga tcatggaagt gatcctgtcc agtacgactg cacaaaagca tttttacgga
    66781 aaactaacag gtgttttact tgttgcatta acgcaaatgg cattatacgg tattattttt
    66841 ggtataggat acagtcaatt caaagatatg gaaatggtca aaaatatatt agacggtatc
    66901 tcattggata acttgattgg accattcttg tggtattctc ttctattcat gatctttggc
    66961 attttgattt tttctgtttt agcagcttta tgtggctctt tggtcaacaa agcagaagat
    67021 acagcaaaag caattttgcc agtgacttat ctatctctag gcggatatat gcttggattg
    67081 atactaggag cttcagatcc aaacaatatc gttattcgga tcacttcgta tattccattc
    67141 ttatcttcat atattatgcc ggttcgctta gcaaatgaga cagtcggtat gggtggagca
    67201 ttgatttcct tgttggtact tgtagccgta acattcttat tgatgatctt gtctgcaaac
    67261 atgtacaaat cgaatgtact cgtgtatagc gaaggcggat tatggagttc attgaaacaa
    67321 tcgatttcaa ttatgagaaa tgaacgaaaa aaagcataaa atatagaaaa atatagaagg
    67381 aagctggaca tttattgttc ccagcttctt ttttgtatag acctatttct atttttttat
    67441 tatattggat atatatattc attgaaaata gagcataaca actttataat gttgagtata
    67501 ccaatttttg gaggcgtttt aatggaccgc tatttagatt tactttcaga gaagttccct
    67561 acaacggaag atgtcatcac ggaaatcatc aatctcgaag caattttgca gcttccaaaa
    67621 ggaacagagt tatttttgag cgatatacat ggcgaatttc ctgcttttga tcatattctg
    67681 cgtatcggtt caggaaatct taaagaaaag atcaaagacc ttttctctga acaaatgacg
    67741 gaaacggaga tcagccaatt cactattttt acggcttatc cagaatatgt gttgacgact
    67801 gattggtaca aaaaacaaga taaatcccag ctgatccatc gtttgatcga tcttttacgg
    67861 tttacgacag tcaaatacac tcgatcaaaa gttcgaaaag gattgccgaa agaatatagc
    67921 tatatcattg aggaactctt gtatatcgat gatcgtatca acgggaaaaa agactatgta
    67981 aaaaaaatca ttgaacaact tgtcttgatg aaggaagaag aaaaattttt aacaaaactt
    68041 gcgcagacga tccaaaaatc tgtcatcgat catttgcata tcgtgggtga tatttttgat
    68101 cgaggaactc aagcagccaa agtaatggat cgaatcatgg atttttcctc tgtagatatc
    68161 cagtggggga atcatgatat tttgtggatt ggtgcgtatt gcggctctga ggcatgttta
    68221 ttgacgcttt tacggattgc cgcacgctac aactatttat ttgaattaga gaaagaatat
    68281 ggattaaatt tacgtccatt attttctttt gcccatcaaa cctatcagaa gaatccagta
    68341 tttaccccta aaaacaggaa agatctatct gaaagagagc aagaagaatt agaaaagatc
    68401 catcaagcac tttctatcct ccaattcaaa tcagaacatc agttgttgaa tcgacgacct
    68461 gaatttaaaa tggacgatcg taaattgttg gaaaaaatca actatgagga atcaacgatc
    68521 gttttagaag gtcagctcta tgagttgaaa gggacttgtt ttcaaacgat ccagccagat
    68581 gatcctaaaa aattcttgga agaggaacaa aaagtgatcg atagtttgat gtattcattc
    68641 cagcactcgt taagaatgca aaaacacatg acgtttttga tcgaaaaagg gggaatgtat
    68701 ctcacgaaca atcagcatgt actgttccat ggctgtatac ctgtagatga aaaggggcag
    68761 ctcttagcat ttgaattaga ccaatcttat cgcggaaaag aactgctggg attttttgaa
    68821 aaacagataa ctgaaagcgc aaaagatttg actgcaaatg aagatttggc gaccgatttg
    68881 atttggtatg cgtggagcgg gccattttcg cctttattcg gcaagagtaa aatggcaact
    68941 tttgagcgct attttctcac agagcctcat acgcacgtcg aaaaaagcaa tccctattat
    69001 cacttgcgag atgaagagtg gttcagtgaa aaaattttgg cagaattcga tgcaaaagaa
    69061 gaaggttcag caatcatcaa tggacacacg ccagtaaaag taaaaaaagg agagtcaccg
    69121 atcaaagcaa acggaaaagc atttgttatt gacggaggtc tatccaaagc ttatcaaaaa
    69181 acaaccggga ttgctggcta ctcattacta tgcaattctt acggtttcca aatcgtgaca
    69241 cattatccgt tcttgcctat tgaacaacaa tttgcaaaaa aatctgatca aacgaatgta
    69301 aaaaaagtga tcgagcagca gctcccacgc aaacttaatc ggaatacgac aaaaggaatg
    69361 gaattacagc aacagattac tcaactccaa aggctgttgg attatcgaaa ggacgattga
    69421 gaaaaatgct agccaacatt gctcaataga ctaaaaagcg actgcaacaa aaggcgtgtc
    69481 gcagtctcct tcggaattag ctcaaaaaac ggtaaaatat tagaagctat ttttctgttt
    69541 atttctctaa tactcaggtc agggcgctga tttcacgacc tcttccttaa acggtgttct
    69601 cctgccaact cctcggtcac aagtcacaat atccaacaaa catgagaagc tgttttttga
    69661 aattgctcct tgtgactcag agttgaacgg caggctcacg acctaatcag aaaaacgatt
    69721 aaaattcatt cacaaagaaa tcgaataaac gctgttcaga tgaatctaca cgatgagaaa
    69781 gttccggatg ccattggaca ccaaggattt tgtgcatatt atctttactt tggactgctt
    69841 caatgagtcc atcgttggaa aaggcgatgg cttttaacaa aggagaaaga tctttgactg
    69901 cctgatgatg ataggaattc acaaagtatg aatcagggag aaggtcactt aataaactgt
    69961 ccgaaacgat tttgacttcg tgagttgcaa actgcggggc agtgggctgt tgttcgtgtt
    70021 ttacggacca ttttggatat aatgaaagat cttgataaag tgttccctcc aacacgacat
    70081 tcaatagttg aagtcctcgg cagactgcaa aaatcggttt tctttgtttc aatgcttcca
    70141 agatcaatgc ctgttcgaat tggtctcgtt gaatatttgt ttccgtcagt tttggatgag
    70201 ggtcttccat gtaaagttgc ggactaacat cctgaccgcc tgcaagaatg agtttgtcga
    70261 ttttctcaat tagttgaggc gctgaatctg gagacatgac tggcagaata agaggtaatc
    70321 cttgagcatc taaaactgca tccacaaatc cctgcggtgt atagcttact tgatttcctt
    70381 ggaaagtatc tgtcgctcga atcagttgat tcccggcaat gccgatgatt ggtttcattt
    70441 ttattccccc taaagtagac taattgtaac aaggatttaa aaaaatttaa actatgtaag
    70501 acttgcccct atacttatct gttcttgctg tgttactatc tgtaaagaga attttcgtgt
    70561 gaaattcatg acgatagttg aaaatattgc ttaatttgtt ataataaaaa gtaagcagaa
    70621 ataaaaaggt tgggcgtaag cttcaaggat ctagttcttc aaggggtgag aaggacattt
    70681 tattgaaggg gcctgcctat actaagttat ctttagaggt acatactttc aatgaaaaaa
    70741 gaaagcatgt acctcttttt taaatcgaaa ggaagtgaag caagtgttag aagctttgga
    70801 acaaatccga aaagcagaag aagaaaatga gaagcgtgct cgaaccctac ggcagcagtt
    70861 gaagacctat gcagaagaaa aagagcaaga attggagata atccaaacga acagtcggca
    70921 acagctgaaa cagttggtag aagaaaaaga acaattcgaa aagcaagaat tagaaaaaga
    70981 aaaaatgaaa ttgaaagcag aagcagacaa ggtgcaagca actttgaaag accaatatca
    71041 aaagcatcag agtcaagcaa tcggtgcaat cattgaaagg gtgaaagaaa cttatggccg
    71101 tcactaagat ggaaaaagtg accctcattt cagataaaag aaatcaggag aggattttac
    71161 aagcagtaca aggaatccaa aatgttgaaa tccgggatct gtatcaaaat agaacaaaca
    71221 accagtgggt agaaaaatat tttccagata ccacgattat tgataaagaa gcaaaattaa
    71281 gcgctttagg caatcggctg aaagacatcc aagaagctat ccaattcata caacaccacg
    71341 gcgatagccg tcaaaagaaa ctccatttga aacgtcaaga actttcctta caagacttgg
    71401 aagcaaatta ttccgaagaa aatttcatga ataaattaga agaagtcctt gatttaaaag
    71461 aaaagtggga acagctaact gaaaaacgtg atcgtttaga agaagaggaa gaatggcttc
    71521 ttcattggca acagctggat attgctccaa gtatgtatgc aagtaagacg accatttttg
    71581 agatggggac tgtgagtgca gcaaattttg aaagtttcaa ggaagaacta agtaagcttg
    71641 atgacgttta tatggaagaa atagattata cgccaaaaca agtttatctt tcgtatgttg
    71701 ctttaaaaaa atcagttgct gctatagaag aaattgctgg gaaatacggg ttcaataaag
    71761 aaacgtatcc ttatgaacaa aatcctaaag aaaaattgca agaaaccaaa cagcaattat
    71821 ccattgttca cgagcagcaa aaaaagataa cgacagcgtt aggtcagtgc agcggctata
    71881 tccaagaatt tgaatgggta gaagaagtca cacttgccgt tgcagaacgg gaaaaagtaa
    71941 aagaacggtt tatccatgcc acttatctga tcgttttgca aggttgggta gatgcagaag
    72001 aaaaacagaa tttgatgcat gtgttaaacg aaactgtatc agaagaagat atatacgtta
    72061 gtttcgaaac accaaactca gaagagattc agcaggaagt ccctactaaa ttgaaaaacc
    72121 atccgcttat cgaacctttt gaattgctga ctgaaatgta cagtctgcca aaatatgaag
    72181 aagtagatcc aacgccttgg atgacaccat tttatcttgt cttcttcggg atgatggtcg
    72241 cagatgttgg ttacggattg ctgatgctca ttgggacaat actagctcaa aaactatttg
    72301 ttttaccccg cgggatgaaa cgtttcgtaa aattctttga gattctctcg gtaccatcga
    72361 tcatctgggg attgatctac agttcatttt tcggacaggc attaccaaaa gaactatttg
    72421 gtatccgctt gcctttccca atcctatcta cgacggatga cgtcaatacg attttgattt
    72481 tatccgtgat tttcggtctg atacagatct tggttggatt attcgtggca gcaaaggaaa
    72541 atatcaggag gaaagattac ttgagtgctg tcagtgatgg ttttgcctgg caagggatcc
    72601 tgattgggat cgttattgca ttgattggtg tcatgttgat aaaaaataca gcatttgttt
    72661 atcttggcgc ggggctatcg atcattgctg ctttatgtat cttaatcgtg ccgattatcc
    72721 aatcgccgtc taaagtcaag ggtgctgcca aaggagcgta taatctttac ggattgactg
    72781 gttatatcgg tgatttagtc agttatacac gtttgatggc actaggtatt tcaggcggaa
    72841 gtattggcgc ggcattcaat atgctagttg ctttcatgcc gccagccgct cgattcagtg
    72901 tagggatcct tttgatcatc gctttacacg cactgaatat gtttttgaca ctgttaagtg
    72961 cctatgtcca tggtgcacga ttgcagtatg tcgaattttt tggaaaattt tatacaggag
    73021 gcggacgtgc ctttgacccg ctgaaaacgg cggaaaaata cgtcaacatc aatcataaga
    73081 aaaaaaacaa taaataattg gaggattttt atacaatgat ggattactta attagtcaaa
    73141 atggtggaat ggtatttgca gtattagcga tggcaacagc gacgattttt tcagggattg
    73201 gttcagctaa aggtgttgga atgacaggtg aggcagcagc agcgttaaca acaagtcaac
    73261 ccgaaaaatt cggacaggct ttgattctgc aattgcttcc aggtacgcaa gggttgtatg
    73321 gattcgttat cgcctttttg atttttatca acttaggaaa tgatatgtca gttgtacaag
    73381 gattgaactt tctaggcgct tctctgccga ttgcttttac aggtttgttt tcaggtatcg
    73441 cccaagggaa agttgcagca gcaggtatcc aaattttagc gaaaaaacct gaacatgcta
    73501 caaaaggaat catttttgct gcgatggttg aaacatatgc gattttaggt ttcgttattt
    73561 ccttcctatt agtattgaat gcctaagcat aaaggaggaa aagcagatga acgccattga
    73621 aaaaatcatc tctcagatga atgaagcagc agagcaagaa agagcggcgt tagagcaaga
    73681 agagcgaatg aagatcgatc aaaactttga acaaaaacgt acgcaaatcg aaacagaaca
    73741 tcaaaaacaa aaagaaaaac aaatcgaatt acttgaaaaa aaataccgtc agcttaggaa
    73801 tcgccaacaa gtagaagtac gacaagaaaa tttgaatgcg aagcaggaat ttttacgacg
    73861 attgtttgca gatgcaatag ctgaaatgga gaattgggat gaatctgaac aaatccagtt
    73921 tatcaaaaat tcattgtatt cattaccttt gacaggcaaa gtaacattca ttgctggaga
    73981 aaaatcagca gcttatcttt ctcagacatt gctggatgaa tggaacaatg aacttccctt
    74041 tatgatggtt ttaagtgatg aaactgttgc tgatcaagcg ggttttctga taaacgatca
    74101 aggagttcag tataattttc ttttcagcag ccttgtacaa gatatccaag gaacgatgag
    74161 ttttgagatt gccaatcaat tattcgaata aggagggatc agtgtatgga ataccacgaa
    74221 ctaaatccct tgattcgcgg aagagagctt gaacttttgt ccaatgagac atttgaacgg
    74281 atgattcaaa caaattctgt cgaagcactt ggtgaaatat tgaaatccac gatttacagt
    74341 ccatatattt atgacggata tgaatatgac ttcgaacaga atcttttaaa ggagcagagc
    74401 cgtctatttc gctggttaaa ggaatcagca ccggagcctg aaatcgtttg gatctatacg
    74461 atgcgctata ctttccataa tctgaaggtt ttgacaaaag ccgagatgac aaatcaaaat
    74521 ctggaccatt tgtatatcga cgatggattt tattcattag aaaccttgaa ggatgccatt
    74581 catacgcaag tttcaaatga actccctgaa agcattatgg acagtatacg agaagtacgt
    74641 gattattttg aagagtctac cattcttcag ggaattgacg tgatttatga tcgacagttt
    74701 ttgacagagc agcgacggct tgccgataag ctaggatatc aagaattgct gacagaagtc
    74761 attgctttta ttgacttgac caatatcaca acgatggctc gaggaatatt gcagaaaaga
    74821 acatatgggt tcatgacgac ggtactttcc agctcgggaa gtatcgaaaa agaagtattt
    74881 ttgaactttg tagataaaga tatggaagat tacacgaatt ttctattaga gacagattat
    74941 gctgattttc tgcgccctgt catccgtgag ggaaatcttg atctcgtaaa gcttgaacag
    75001 ttgaaagatg attatctaag ttcattgtat caagaagcac aaacccaggc tttcggacca
    75061 ctgccactac tagccttttt gaacgcaaaa gaggtagaaa gcaaaaacct tcgtttactg
    75121 gttatcggca aaagaagcca tttcgaacca gaaacaatca gaaagcgggt gagacaagtc
    75181 tatgacgcat aagatcggtg tagttggcga caaagattct gttttgccat tcaaattgtt
    75241 tggctttgat gttcgttatg gtacaaccaa gcaaaccgtt cgtcaggcaa ttgaagaaat
    75301 ggcaaagaat gagtatggcg tgatttatgt cacagagcaa tgtgcagcat tgagcccaga
    75361 aacgatcgaa cgttacaagg aacaaatgat acctgctatc gtattgattc ccaatcatca
    75421 aggatcatta gggatagggc tggaagaaat tcaaaaaaac gtagaaaaag cagtaggtca
    75481 aaatatctta tagtatgaaa aggagataga aattttgcaa attggaaaaa tcataaaagt
    75541 ctccggacct cttgtaatgg ctgagaacat gtctgatgcc agtatccaag acatgtgtct
    75601 agtgggagat ctaggagtta tcggagaaat tatcgagatg cgtggcgatg tggcgtctat
    75661 tcaagtatat gaagagactt ctggaattgg tccaggcgaa ccggttcgct ctactggtga
    75721 agctttatct gttgaattag gaccagggat catttcacaa atgtttgacg gaatccaacg
    75781 gccattagat acctttatgg aaatcacaca aagtaatttc ttagggcgcg gagttcaatt
    75841 gcccgcattg gaccatgaga aaaaatggtg gttcgaacca acagtagaag ccggagaaac
    75901 ggtgagtgct ggagatgtta tcgggatcgt agaagaaaca aaagttataa aacataaaat
    75961 catggtgcca aatgggataa aaggaacgat caaaacaatc gaaaaaggtt cattcactat
    76021 tgatgaaaca gtatgtgtca ttgaaaccga aaatggtgac aaaaatttga cgatgcttca
    76081 aaaatggcca gtaagacgta gtcggccaat caaagaaaaa ttaaacccgg atgcacccat
    76141 gatcactgga cagcgagtga ttgatacatt cttcccagtg acaaaaggag gagcagcagc
    76201 tgtacctggt ccttttggtg cagggaaaac agtcgttcag catcaaattg caaaatgggc
    76261 cgatgtggac atggttgtct atgtgggatg tggcgagcgt ggaaatgaga tgacggatgt
    76321 tttaaatgaa ttccctgaat tgattgaccc taatacagga gaatcgttga tggaacgtac
    76381 ggtattgatt gctaatacat caaacatgcc agtagcagct cgagaagctt ctatctatac
    76441 gggaatcaca attgcggaat atttccgtga catgggttat gacgttgcta tcatggcaga
    76501 ctccacttca cgatgggcag aagcacttcg tgagatgagc ggacgtttgg aagaaatgcc
    76561 tggtgatgaa ggttatccag cttatcttgg ttcacggctt gcggaatact atgaacgatc
    76621 tggaagagtc attgcattag gatcagaagg tcgcgaagga agtataaccg caatcagtgc
    76681 tgtatccccg tctggagggg atatttcgga accagtcaca caaaatacat tgcgggtcgt
    76741 aaaagtattc tggggtcttg attccagttt agcccaaaaa agacattttc cttcgatcga
    76801 ttggatacaa agctattctc tttattcaac agaagtaggg aagtatatgg atcatatcct
    76861 tcaagctgac tgggcatcca tggtcaccga gggcatgcgt attttgcagg aagaacagca
    76921 gctgaatgaa atcgtgcgtt tggtagggat tgattccctt tcagataatg accgtctgac
    76981 attagaagtg gcaaaatcca ttcgtgaaga ttatttgcag caaaatgctt ttgatgatgt
    77041 cgatacattc acttcaagag agaaacaatt caaaatgttg aagatgatct tgacctttgg
    77101 tgaagaagga cgccgtgcgt tgtcgttagg tgcttattta agtgagatca tggacggtac
    77161 cgtatcgatt cgtgaaagga tcggacgaag caaatatatc ccggaaacag aattagaaaa
    77221 actagatcaa attattggtg aaatcaagca aacgatgcaa acgatcgttt cagaaggagg
    77281 catgagcaat gattaaagaa tatcgtacga tcggtgaagt cgtcggtcca ttgatggcgg
    77341 ttgaaaaagt tgctggtgtc aaatatgaag aattaatcga agtccgtatg caaaatggcg
    77401 agattcgtcg tggacaagta ttggaagtcc aagaagataa agcaatggtc caaatattcg
    77461 aaggaacaag tggtatcaat ttacgtgact cttctgtacg atttttaggc catcctttag
    77521 aactaggtgt atcggaagac atgatcggtc gagtattcga tggtttggga cgaccgaaag
    77581 ataacggacc agagatcctg cctgaaaagc atttggatat taacggagaa gtaatcaatc
    77641 cagtagctcg ggattatcca gatgagttta tccaaacagg tatctctgca atcgatcatt
    77701 tgaatacatt agttcgtggg caaaaattac cagtattttc tggctctggt cttcctcata
    77761 aagaattagc tgctcagatc gcgcgacaag caacggtact cgattcatca gatgatttcg
    77821 ccgtagtctt tgctgctatt ggaatcactt ttgaagaagc tgaatttttc atggaagatt
    77881 ttcgtcaaac gggcgcaatc gaccgttctg tcatgtttat gaatttagca aacgaccctg
    77941 caatcgaacg tatcgctact cctcgtatgg ctttgactgc tgcagaatat cttgcttatg
    78001 aaaagggaat gcatgttttg gttatcatga cagacatgac caactatgca gaggcattgc
    78061 gagagatttc tgcagcacgg cgagaagttc caggaagaag aggatatcct gggtatcttt
    78121 acacgaactt agctacttta ttcgaacgag caggaagaat ccgcggacta aaaggatcgg
    78181 ttactcaaat tccgattcta acaatgccag aagacgataa aactcatcca atccctgact
    78241 tgactggtta tattacagaa ggacagatca tcttgactag agagctttac aagagtggga
    78301 ttcagccacc aattgatgta ctcccgtctc tttcgcggtt aaaagataag ggaactggac
    78361 ccggaaagac aagagaagac catgcagcta cgatgaatca gctttttgca gcctatgcac
    78421 aaggaaaaca ggcaaaagaa ttagccgtag ttttaggtga atctgcttta tctgatgtag
    78481 acaagatcta tgcgaagttt gctgagcggt ttgaaaaaga atatgtcaat caaggattct
    78541 acacgaaccg ttcgattact gaaacacttg atctagggtg ggaactgcta tcgatgttgc
    78601 caagaaccga attaaaacga atcaaagacg acatgctgga caaatatctg ccagaaggga
    78661 agtgagttct gatggcacga ttgaatgtga atccgacccg catggaattg actcgattga
    78721 aaaaacagtt gacaactgcc acaagagggc ataaattatt aaaagataag caagatgaac
    78781 tgatgcgtca attcatcctg ttgattcgaa agaacaacca gctgcgtcaa gaaatggaag
    78841 agtctatgac agaagcaatg tctgattttg tattggcaaa tgcttcgatc acggaacctt
    78901 tcatcgaaga attatttgtt ttgccggcgg aaaacgttga tttgtctatc gtagacaaaa
    78961 atatcatgag tgtaaaagta cctgtgatga attttgaata tgatgaacag ctgacagaca
    79021 cacctttgga atacgggtat ttgaattcca gtgccgaact ggatcggtca atcgatcggt
    79081 ttactaccct gcttccaaaa cttttggaac tgacagaaat cgaaaaaact tgtcaactga
    79141 tggcgagtga aatcgaaaag acacgtcggc gagtcaatgc attagaatat atgacgatcc
    79201 ctcaattaga agaaacgatc tattatattc gtatgaagct ggaagaaaac gagcgcgcag
    79261 aagtaacaag gttgatcaaa gtaaaaaata tgggtaccac tgactaagtg gtatcttttt
    79321 ttaaaagagg aaaacgatga ttaaacaaag caaacaaata aagaaacgtt tgccggctgt
    79381 tcagcttctc gcattaggat tttttctcct gattttagtt ggcggcggcc tacttaccct
    79441 accatttttt agtaatagtg ggcatgggac aaattttatc gatgcgcttt tcactgcaac
    79501 ttctgctgtc tgtgtaacgg gattgacaac attgaataca gcagagcatt ggaacagtgc
    79561 tggtcaattt ttgatcatgc ttttgattga gatcggcggt cttggtttta tgatggttcc
    79621 gattctatgc tttgcattga taaagaagaa agtcagtctc agcacacgta ttatattaaa
    79681 agaagcgctg aatctagaag aagtatcagg tgtgatgaag ctcatgcttt acatcctaaa
    79741 attggccttt gttatccaat tgattggtac ggttgcttta tcttttgtat ttgtgcctga
    79801 atttggctgg ttgaaaggta tctggtacag tttgttccat gcaatctcta gtttttgtaa
    79861 tgcagggttt gatttgttag gagacagttt agccaatcac cagcaaaatg tttatttgat
    79921 catggtggta tctgctttga tcatttctgg tgggttaggc ttcatcgtat ggcgtgattt
    79981 actggaatat catcagaaaa agaagatgac gattcattca aaaatcgcat taaccgttac
    80041 aggtaccctt ttattaggcg gattcgttgt gttctttttc acagagcgca atggggcaac
    80101 gctagtggaa gggaatatgt ttcaacgatt ggcaaacacc ttttttatga gtgtgacacc
    80161 tagaacggct ggatattatt cagttgatta cctccatatg agccatgcag gtctgatttt
    80221 aacgatgttt ttgatgtaca tcggcggaac atctgggtcg acggccggcg gattgaaaac
    80281 aactacgtta ggtgtgttgc tgatccagat gcgttcgatg ttgaaaggac gtacgagagc
    80341 ggaagcattt ggccgtacca tccgacaagg cgcagtgttg cgggcactta ctttattttt
    80401 tgttacgttg acgttgtgtg tagtcgccat catgatttta tcggtgactg aaacgatacc
    80461 taaaacttct ggcatcgaat atattgcttt tgaggtcttc tctgcgtttg gtacagtagg
    80521 tcttacgatg ggattgacgc cagacttgac tgcaataggg aaattgatca ttatagcgct
    80581 tatgtacatt ggacgagttg gtgtattgac tgtggtcttc tctctgatga caaaagcaca
    80641 aagaacacaa tcaaaataca aatatccaga agaaagtgtc atgattggat aatttcatct
    80701 tctgacagaa acctagtgat ttagtaaaat aagaaaataa aataattttt cttgcttctt
    80761 ggatacttta agtgcaaaat gttcgtttat tttttgaggc actacccgtt gttgaacctc
    80821 gggtagtgcc tcttttttat tgaaaggaat caataagatt tgattccttt atttatcaat
    80881 aggttataat tcatattttt ttattttttc ttttacgata cttagtccag aagctaaaat
    80941 ttcaaggtta ttagaggata gggaaattcg aacgaatgca tctggttgcg cacgtgtagt
    81001 aaagcgtctg gaatgataaa gtcggatacc gttagcaaga aagtcattct caattatctt
    81061 agggtcaatc tcaggatcaa ctggaagaat tcgatagtaa gggacacgat tcgttggttt
    81121 ttctactttg aaaagagaat caaaaagctg attggctctt tttgtaagac ttaatttagt
    81181 ttctaagatc ctatttgctt catttgaatg gaggatttga gtgatgactt ccacatctaa
    81241 tccagaagtt ttcacattta tattaaaaat tgcttgttct atcttgcttt ggacatgtac
    81301 tggaactaca agataagcaa ctcgcaatcc agaacaaata aattttgtca ttccagctaa
    81361 gtagattgtt tggttaggta ataaattttg gaaaggagga atgatcgtat gttgatagta
    81421 agttgttaaa aatgaatgga tatcatcttc aataacccat agaccttctt tttcaatcac
    81481 ttcggctaat tgctctcgtc ttttgtgaga gatttgaaac cctataggat tattacaaga
    81541 aggcataaga aagacaccat gaatcttctt ttttctacat tcctgaatca atatatcagg
    81601 tcgcattcct tgctcgtcaa aatcaattgg aacgatctct aaatgatata actgagccaa
    81661 ttcaatgaaa ttagcgtatg tatatcggtc tgttgctatt ctatcacctg gagagaaaag
    81721 tgcagaaagt gtgatagcca atccattttg aacaccggaa acaatagata gagattctaa
    81781 ggacggaatg actccttgag tttttaacca atttgctgca gtagtcaatt gaaaatttgt
    81841 gcctttggga tcttggtaat taagcaaacc aacaagattt gggttattac tagttgattg
    81901 aataaacggg acaacgaatt tattacattc ttcaaaagaa ctaaccagac caaaatcaat
    81961 gatatgttcg gttacttcat tggtagagat ggtgatggac tcaaagacat tgggagaaat
    82021 aaatgtgcca cttccaatat tcgtatacag caaacctttc tcaattccat atttataagc
    82081 cttgccaacg gtagtaaaat ttaaatctaa ataatcagct agctctcttt gggagggtaa
    82141 ctgagtgttt ttctgtaatt tattctttaa aatatcttgt tctaattgtt gaatcaacga
    82201 tcgataataa ggacgcttca atttttgttt gtctggtcgc caagttaacg ggtaattgtc
    82261 ataagaatta ataggcattt tctccactcc ttaaaattgt ataccataca attttaccat
    82321 tgattgtatt gattttagaa gttaatcttt tgtgaggagg gaattgtcta tgaaaattat
    82381 taattttgag gaagtagtag cttcttttag ttttgaagaa gcgattcaag taatgaaaaa
    82441 atgttttttt gattatgaaa gtggtaaaat cagccaaaat cctcgattgg tggaaatttt
    82501 acctgacgga aaaggcaaaa atatgtttgc gatgatgcct gcttatttgg gggagaacag
    82561 atattttggc acaaaagtca ttaccgcttt tccggataat catcagtatc atttaccttc
    82621 tcatttagga gagattttct tgtttgatgc tcaaaacgga ctacccaaag cattgataaa
    82681 cgcaaatgca gtcacctgga ttcgaacagc tgctgtatct gcgctggcaa cagattactt
    82741 agcaaatccg catgcagaaa cacttgcttt aattggagct ggtcaacaag cattgtcgca
    82801 tttgactgcg atttctacca ttcgtcccat cactacagtg tttgtttacg atattttaga
    82861 agaaagacga aatactttta tcgctaaagc taaaaaacag tatcctaaaa taacgtttat
    82921 aaatgcaata tcagtagaag atgcagtacg tccagcggaa atcatttgta cgttgacctc
    82981 tagtaaagag gcatttcttc aaaaagagtg ggtaagggaa gacgcacata tcaatgctgt
    83041 gggcacattt actcctgata caagagagat aagtacatcg ttgatggaaa cttctcaaat
    83101 ctatgtagat gattactcag ctgccttaac agaaagcggg gacctgctta tagccatggc
    83161 agaaggagat ttagaggaat cttgtattgt tggtacatta ggcgaattag tttctgagaa
    83221 aaaaacattt tataaaggag aatcgaggcc gacgattttc gacgcagttg gtctagctat
    83281 tgaagatctt tgttgtgcag aatatattta taacaaatta gagaaagggg ctttaaaatg
    83341 aacttagatt attacgtagt tgatgcattt gcagatgagg tgttcaaagg aaatccagca
    83401 gcggtttatg tgctagaaga atggctgcca gaaggtacga tgcaaaaaat tgccattgaa
    83461 aacaatttat ctgaaacagc atttacagtg aagaaaaacc aagaatttga gcttagatgg
    83521 tttacgccag atcgagaaat cgatctttgt ggtcacgcga cattagcaac agcatttgtt
    83581 ttatttaact attacaaaat acctgatgaa acgattaaat tttctactca aagcggtaat
    83641 ctatttgtga caagaattaa agattattat tacatggatt ttcctagtat tatgccgaaa
    83701 aaagtgccga tattgtctga atatgaagaa gcgattgggg ctaagattaa agaagcctac
    83761 ttagcacgtg atttattttt cgtattagaa gatgaaaaaa cggtggctaa attgcagcca
    83821 gattttacag ctatcaaaaa ttttgaatta ggaataggag tcatcgtgac agcagaaagt
    83881 gtgcaaaaag actttgtttc tagaaccttc tttccaaaat taacaatcaa tgaagatcca
    83941 gtatgtggat cagcacattc taatcttatt ccttattggg cagaaagaat gaataaaaca
    84001 aaattgtcag cttatcaaat gtcatcaagg ggcggggatc tagaatgtga attaaaagaa
    84061 gatcgtgtga taataggagg aaaagcagtt ttgttttcta aaggtacctc gtttatttga
    84121 tttctttcaa atgaattaaa aataaattgg tggagagtgg caaccttata gctacaatgg
    84181 ttgttaaaaa aagacgcaaa ctttttcaat ttaatgaaaa gtttgcgtct cattttaatt
    84241 attggtgttt gttttttatt caatcaagag taaaatgccc catactaact atcctcggat
    84301 gacttcgatt ttataaccat cagggtcaat gacaaagtag taagaaggcg cagtgccagg
    84361 taatcctttt aagtcagtaa tctcaagacc ggcagcttta tgttgctcgt gtaatttttc
    84421 tagatcatca gctgctatag cgatatgacc atagccgtct cctagatcat acgcaccatg
    84481 atcatagttg taagtcaact ctaattcata gtcatcccca ggaagtgtca aataaacaag
    84541 tgtaaatttg ttttctggaa aatcacggcg gcggctttct tcaaaaccaa atgccttttg
    84601 ataaaattcg attgatgctt caagatcttt cactcgaaca catgtgtgag ccattttcat
    84661 agattcatct ctccttttcc ttttactcaa tcataacaaa aagaagtaag gaaatagttg
    84721 atttgtgctt gttcatgaga aatttctcat gtaaaatgga tagaaaataa aactgttaag
    84781 gtggaaacta ttcatggata aaccaatttt tggtgaaaaa aagcaatttg ctgattatca
    84841 aacccgttat gcagcatata ttgtcataga aagagatcag cagattgcag taatcgaggc
    84901 tccaaatggt gctttttttc ttcctggcgg ggaaattgaa ggagaagaga cgaaagaaga
    84961 agcgattgtc cgtgagctga tagaagaaat gggaattgtg gcagaaattt cttcttatct
    85021 gggagaagct gatgagtatt tttactcgaa ttatcgtgca acttattatt ataatccagg
    85081 atatttcttt gttgctgatt cttggaagcg tataggagaa ccaactgaaa agaccaataa
    85141 aatttggtgg gtgagccctc aagaagcgct tgtgaaattg aaacgtggta gccaccgatg
    85201 ggcagtcgag agatggatcg aaaaaaataa aaactgaaag aaagcgagta gatcagcttt
    85261 ctctcagttt ttttatttat tacagtacat attttttgat tgcttcagct acaccgtgct
    85321 cgtcgtttga tgaagtgatg acatttgctg cttctttgac aagagaaacg gcatttccca
    85381 ttgctactcc tagaccagca tattcaatca tggataagtc gttctcgtta tctccgatag
    85441 ccatgatttc atcttgatca ataccaaggt gctgtgcgag attcgcaact gccgcacctt
    85501 tacttgcttc tttatttagt acttcgaagt aatagggcgc acttttgacc gttgtgtatt
    85561 tatcacggaa agtttgcggt aaacgcgcaa ttgctgcatc taaaatttct ggttcgtcga
    85621 tcatcatcat tttgacgatg ttcatgtctg gtgtcatttc ttcaggtgtt cgatatttta
    85681 gcggcatctt gactaaactt gcttcgtgga tcgtataagc gctgatatct cgattaggcg
    85741 tgtagatcgc tttgtcatcg atcgaatgga gatgactgcc gacacggcgt gccatcactt
    85801 cgatctctag gaaatcttca tgtgtcagtc cgtgacgggc gatgatttta cctgatttcg
    85861 tttgttgtac gagtgccccg ttataagtaa taacgtaatc attatcttga aaaaggttca
    85921 actcgtttaa ctgttcctgg acacctggta agggacggcc agtgcataaa acgatcgaaa
    85981 caccttttgc aacagcagcg gcaatcgctt cttttacttc ttttgttact tctcttttct
    86041 catttaataa agtaccatcg atgtcgatag cgactagttt gatagacata atttcctcca
    86101 atatatttta atttatttca atcaatgcgc cattacggat atggctggca aattcttgat
    86161 aagtttcgtc aaataaatca taatgatcac gcaaggacgg atcaaccatt tcttttggaa
    86221 agaaaaatcg ctcatctcct tgttcttgtc ccgctaatgc agcaacaagc tgactaacct
    86281 gtgataattc tatcaaagtt ccgtcatttc gcaaaatctc gatttgtgtg cgatgtctgc
    86341 cttgttctgg gcgataaaaa tcataaggta gatcgtagct agaattcaca gcagtgtaat
    86401 aaacaggatt atatccgacc ttttctacta acaaagtgag ttcttggact aattttgaat
    86461 cccggttgcc agaaaaagta gcagatttca gtggtttacg attcaaaaaa cgtttagcta
    86521 aatcatttaa aataggatca gcagattcag accattgagt aaagtaagtg cccaagaccc
    86581 catcatcaag tttgaggtat tcttctaaag taaagcttcc gtcaagaaat ggcagaagta
    86641 attgagaatg gagttcaaaa ctgctggcat cttcttgata caactcgtgt gcgcgatgaa
    86701 gcagatgctc caaaattact tccataccac gggaaacagg atggaagtac acttgcacat
    86761 acatttgata tcggctaacg atataatctt ccactgcatg catgccactc atggaaaaag
    86821 cgatcccgcc ttcataagga cgaatcacac gtaatattcg ggtaagatca aatgttccat
    86881 attctgttcc agtgaaataa gcatcccgaa gcaaatagtc cattcgatct gcatcgatct
    86941 gactagaaat catttggaca acttgtgggt tggggtaagt tttttggatc acactagcta
    87001 ccttttcagg aaaaccttct tctactcggt taagaatctg atacacttct gtttctggag
    87061 aagtgatgat ctctacagtg atggcttcat gattcgtatg gaagatatgt tcaaatgtat
    87121 gagagtaagg accatgaccg acatcatgca acagtgccgc acataaagtc accagccgtt
    87181 cctgatcatc ccagcctccg ttgcctattt tttcttttga aaaatttcga gaaaagatat
    87241 cgcagattcg tcttgaaatc tcataaacgc ctaatgaatg agtaaaacgg ctatgttctg
    87301 ctccgtgaaa agtgaaagaa gaagtgccta attgtttaat gcgtcgtaga cgttggactt
    87361 ctttcgaatt gatcaaatct aagattactt gatgctggac atggatatag ttatggactg
    87421 gatcacgaaa aactttttcc ataggcagca tttgatattt ataaggggtt gtcataatgt
    87481 agctccttta tgttattacg ttgttccatt ctctggattt ggttgttcca ttgctccagc
    87541 tggatttctt tttttagcca gtcggtagaa tcctgtaaat cacttgcaga atacagcttt
    87601 tcaaaagctt ttgcaaatgc ttctttgact tcttttacaa aaaggggttg gtcaagcagt
    87661 tcttcaagtg ttgccattgt agcaggatcc actgcaggat agccatttgt accaaagtct
    87721 tcttttaaag cagattgata aaatcgcttc atgacttgcc cgcgtttttc ctgattaccg
    87781 ttgacactta agtacatcat aacagaaatc ccatttttga tccgacgctg agcgataccg
    87841 gcaaattttt tgccatggat gcttaaatca taagttccag gacaataaga atgggtgatt
    87901 tcgaatgctt gtatcggtgc ctttggaaaa gcgtatttag tcaataggag catttgctcg
    87961 taagcgtcat ctatggttat tttttttgtg tcactttggg ggaaaatcaa agaaatattc
    88021 aaaattcctt catctgatac gatccctaat ccacctgaat ttctgatcac tggagcgtaa
    88081 cctgcatctt tcagtgtttg gatcccgtca cttagaaaag gagttcgaac atccttcata
    88141 cctaagatga ctgtgcagtc atattgccag aaatgtaaaa agatttgctg gtgttcttta
    88201 gaatattccg ttaatatatc tgttaatgca aaaggggaaa agtcgttttt ttgataaatg
    88261 tgctgatcta gtcgaatcgc agggttcatt caaccggctc ctttgtataa attcatattt
    88321 tctacaatat tatactctaa aatcaaagag ttgttttgga aaaaaggttt tctgtaaaaa
    88381 tggacaagtt ggttgacaaa acaaaagaaa ctaggaacaa tgtagctatg agaagtaaag
    88441 gagaatgaat aatggaatta tcacaaggaa caccgatttc aatcaaattg cgtacaaaag
    88501 taaaacagca aggggaagtg caagattttt attttgattt gaaagggcaa atggtgacaa
    88561 ttggcgatac gctgtacata cgttataaag agattcagga ggagacgggc gatgagattc
    88621 ctgtaacgat caaattagtt ccagatggtc atgtacagct gatccgtgca ggagaaatgc
    88681 ggatgcgttt gaaatttggc tataaagaac ggttagaaac atcctatcga acaccatacg
    88741 gtatgatcca gattgctact tttacgaaag aactgcatgt tagtttgaaa gaccgtccca
    88801 caggagggaa ggttcgaatc gattatgatc tgttcatggg accggaaaaa atcggcgaat
    88861 attatttgac cttggatttt acagcgtaaa tataaaagaa aagtttgatt ttttgtgtct
    88921 gattttgtat gataaggagt agactgtgaa aggacgtgtc ctgattggaa attagtgtat
    88981 ttgaaggtgc aaacaaaagc gaattatcaa tgatcgaagt agcacacgcg atcttagaac
    89041 aacgtggcga tgtcatggat ttttctgatt tagctaacca gatccaaaac tatcttggga
    89101 aatcagacag tgaaattcgt gattcactcg cacaatttta tactgacttg aatattgacg
    89161 gcagctttat ctcattaggg gataatcgtt ggggcttgcg ttcatggtat gctatcgatt
    89221 cgatcgatga agaagtaaac catggaatgg acgaagagga tgaagatact ccacgtcgcc
    89281 gtaaacgcaa gaaagtcaac gcctttatca atgatgatga agacgcgatc gattacaatg
    89341 acgatgaccc agaagataca gatctgacag aagaagatga cgatgatctg tttgatgacg
    89401 atgatgatga agatgaagaa atcgctgctt ataattctga cttgcaagaa atcggagcag
    89461 atgacccgac agatgatgaa gaagacttgc caggaaatat cgaagaagat ttaagtatca
    89521 tagacgaaga cgatgatgat gaagattatg aagaggaaga attttctgac tctgaaaaag
    89581 aataaacatt attttcttac gagaggttgt gacagagacg atcagcctat cagaataagg
    89641 aggtgtgaca cgat
//
LOCUS       DARBDN010000003        76452 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000003 DARBDN010000000
VERSION     DARBDN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.003"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            84..1142
                     /locus_tag="SCH06_000197"
     CDS             84..1142
                     /locus_tag="SCH06_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HEG1076804.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1146..2180
                     /locus_tag="SCH06_000198"
     CDS             1146..2180
                     /locus_tag="SCH06_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HEG1076805.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2282..2998)
                     /locus_tag="SCH06_000199"
     CDS             complement(2282..2998)
                     /locus_tag="SCH06_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEG1076806.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     QPLTCYELTKNGRKKLTDYC"
     gene            complement(2967..3752)
                     /locus_tag="SCH06_000200"
     CDS             complement(2967..3752)
                     /locus_tag="SCH06_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HEG1076807.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDGGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3743..4492)
                     /locus_tag="SCH06_000201"
     CDS             complement(3743..4492)
                     /locus_tag="SCH06_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEG1076808.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4790..5314
                     /locus_tag="SCH06_000202"
     CDS             4790..5314
                     /locus_tag="SCH06_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HEG1076809.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5330..6829
                     /locus_tag="SCH06_000203"
     CDS             5330..6829
                     /locus_tag="SCH06_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HEG1076810.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6917..7519)
                     /locus_tag="SCH06_000204"
     CDS             complement(6917..7519)
                     /locus_tag="SCH06_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEG1076811.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7623..8579
                     /locus_tag="SCH06_000205"
     CDS             7623..8579
                     /locus_tag="SCH06_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEG1076812.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8884..9840)
                     /locus_tag="SCH06_000206"
     CDS             complement(8884..9840)
                     /locus_tag="SCH06_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1076813.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10014..10574
                     /locus_tag="SCH06_000207"
     CDS             10014..10574
                     /locus_tag="SCH06_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076814.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10567..11391
                     /locus_tag="SCH06_000208"
     CDS             10567..11391
                     /locus_tag="SCH06_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEG1076815.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11401..12018
                     /locus_tag="SCH06_000209"
     CDS             11401..12018
                     /locus_tag="SCH06_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEG1076816.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12036..12719
                     /locus_tag="SCH06_000210"
     CDS             12036..12719
                     /locus_tag="SCH06_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEG1076817.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13402..14637
                     /locus_tag="SCH06_000211"
                     /pseudo
     CDS             13402..14637
                     /locus_tag="SCH06_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
     gene            14645..15532
                     /locus_tag="SCH06_000212"
     CDS             14645..15532
                     /locus_tag="SCH06_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1076818.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15549..16385
                     /locus_tag="SCH06_000213"
     CDS             15549..16385
                     /locus_tag="SCH06_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1076819.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16388..17011
                     /locus_tag="SCH06_000214"
     CDS             16388..17011
                     /locus_tag="SCH06_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076820.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQPDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17008..18300
                     /locus_tag="SCH06_000215"
     CDS             17008..18300
                     /locus_tag="SCH06_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1076821.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18659..18756
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18872..19453
                     /locus_tag="SCH06_000216"
     CDS             18872..19453
                     /locus_tag="SCH06_000216"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEG1076822.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19456..20763
                     /locus_tag="SCH06_000217"
     CDS             19456..20763
                     /locus_tag="SCH06_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEG1076823.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21056..21544
                     /gene="purE"
                     /locus_tag="SCH06_000218"
     CDS             21056..21544
                     /gene="purE"
                     /locus_tag="SCH06_000218"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEG1076824.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21537..22661
                     /gene="purK"
                     /locus_tag="SCH06_000219"
     CDS             21537..22661
                     /gene="purK"
                     /locus_tag="SCH06_000219"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEG1076825.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22674..23969
                     /gene="purB"
                     /locus_tag="SCH06_000220"
     CDS             22674..23969
                     /gene="purB"
                     /locus_tag="SCH06_000220"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEG1076826.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24149..24526)
                     /locus_tag="SCH06_000221"
     CDS             complement(24149..24526)
                     /locus_tag="SCH06_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076827.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            24782..25510
                     /locus_tag="SCH06_000222"
     CDS             24782..25510
                     /locus_tag="SCH06_000222"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEG1076828.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25510..25764
                     /gene="purS"
                     /locus_tag="SCH06_000223"
     CDS             25510..25764
                     /gene="purS"
                     /locus_tag="SCH06_000223"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HEG1076829.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            25766..26437
                     /gene="purQ"
                     /locus_tag="SCH06_000224"
     CDS             25766..26437
                     /gene="purQ"
                     /locus_tag="SCH06_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HEG1076830.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26438..28660
                     /gene="purL"
                     /locus_tag="SCH06_000225"
     CDS             26438..28660
                     /gene="purL"
                     /locus_tag="SCH06_000225"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HEG1076831.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28645..30084
                     /locus_tag="SCH06_000226"
     CDS             28645..30084
                     /locus_tag="SCH06_000226"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEG1076832.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30107..31159
                     /locus_tag="SCH06_000227"
     CDS             30107..31159
                     /locus_tag="SCH06_000227"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEG1076833.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31156..31734
                     /gene="purN"
                     /locus_tag="SCH06_000228"
     CDS             31156..31734
                     /gene="purN"
                     /locus_tag="SCH06_000228"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEG1076834.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31731..33266
                     /gene="purH"
                     /locus_tag="SCH06_000229"
     CDS             31731..33266
                     /gene="purH"
                     /locus_tag="SCH06_000229"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEG1076835.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33282..34556
                     /gene="purD"
                     /locus_tag="SCH06_000230"
     CDS             33282..34556
                     /gene="purD"
                     /locus_tag="SCH06_000230"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEG1076836.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34678..35592
                     /locus_tag="SCH06_000231"
     CDS             34678..35592
                     /locus_tag="SCH06_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEG1076837.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35725..37290)
                     /locus_tag="SCH06_000232"
     CDS             complement(35725..37290)
                     /locus_tag="SCH06_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEG1076838.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37283..38734)
                     /locus_tag="SCH06_000233"
     CDS             complement(37283..38734)
                     /locus_tag="SCH06_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1076839.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITA
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(38748..39764)
                     /locus_tag="SCH06_000234"
     CDS             complement(38748..39764)
                     /locus_tag="SCH06_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1076840.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            39984..41072
                     /locus_tag="SCH06_000235"
     CDS             39984..41072
                     /locus_tag="SCH06_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEG1076841.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41126..42652
                     /locus_tag="SCH06_000236"
     CDS             41126..42652
                     /locus_tag="SCH06_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEG1076842.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42654..43859
                     /locus_tag="SCH06_000237"
     CDS             42654..43859
                     /locus_tag="SCH06_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1076843.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44116..45093
                     /gene="guaC"
                     /locus_tag="SCH06_000238"
     CDS             44116..45093
                     /gene="guaC"
                     /locus_tag="SCH06_000238"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEG1076844.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45357..46781
                     /locus_tag="SCH06_000239"
     CDS             45357..46781
                     /locus_tag="SCH06_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEG1076845.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47242..48351
                     /gene="pdhA"
                     /locus_tag="SCH06_000240"
     CDS             47242..48351
                     /gene="pdhA"
                     /locus_tag="SCH06_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HEG1076846.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48354..49331
                     /locus_tag="SCH06_000241"
     CDS             48354..49331
                     /locus_tag="SCH06_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEG1076847.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49356..50999
                     /locus_tag="SCH06_000242"
     CDS             49356..50999
                     /locus_tag="SCH06_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HEG1076848.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51007..52413
                     /gene="lpdA"
                     /locus_tag="SCH06_000243"
     CDS             51007..52413
                     /gene="lpdA"
                     /locus_tag="SCH06_000243"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEG1076849.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52575..52850
                     /locus_tag="SCH06_000244"
     CDS             52575..52850
                     /locus_tag="SCH06_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEG1076850.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            52856..53623
                     /locus_tag="SCH06_000245"
     CDS             52856..53623
                     /locus_tag="SCH06_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEG1076851.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            53791..55620
                     /gene="typA"
                     /locus_tag="SCH06_000246"
     CDS             53791..55620
                     /gene="typA"
                     /locus_tag="SCH06_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEG1076852.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            55881..57653
                     /gene="recQ"
                     /locus_tag="SCH06_000247"
     CDS             55881..57653
                     /gene="recQ"
                     /locus_tag="SCH06_000247"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HEG1076853.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            57767..58069
                     /locus_tag="SCH06_000248"
     CDS             57767..58069
                     /locus_tag="SCH06_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HEG1076854.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58072..59235
                     /locus_tag="SCH06_000249"
     CDS             58072..59235
                     /locus_tag="SCH06_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEG1076855.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59261..62689
                     /locus_tag="SCH06_000250"
     CDS             59261..62689
                     /locus_tag="SCH06_000250"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HEG1076856.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            62710..63834
                     /locus_tag="SCH06_000251"
     CDS             62710..63834
                     /locus_tag="SCH06_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076857.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            63824..64261
                     /locus_tag="SCH06_000252"
     CDS             63824..64261
                     /locus_tag="SCH06_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEG1076858.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64245..64583
                     /locus_tag="SCH06_000253"
     CDS             64245..64583
                     /locus_tag="SCH06_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEG1076859.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            64702..65262
                     /gene="rsmD"
                     /locus_tag="SCH06_000254"
     CDS             64702..65262
                     /gene="rsmD"
                     /locus_tag="SCH06_000254"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEG1076860.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65259..65750
                     /gene="coaD"
                     /locus_tag="SCH06_000255"
     CDS             65259..65750
                     /gene="coaD"
                     /locus_tag="SCH06_000255"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEG1076861.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            65740..66783
                     /locus_tag="SCH06_000256"
     CDS             65740..66783
                     /locus_tag="SCH06_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEG1076862.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            66942..67670
                     /locus_tag="SCH06_000257"
     CDS             66942..67670
                     /locus_tag="SCH06_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEG1076863.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            67786..68031
                     /locus_tag="SCH06_000258"
     CDS             67786..68031
                     /locus_tag="SCH06_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEG1076864.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68028..68246
                     /locus_tag="SCH06_000259"
     CDS             68028..68246
                     /locus_tag="SCH06_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEG1076865.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68382..68921
                     /locus_tag="SCH06_000260"
     CDS             68382..68921
                     /locus_tag="SCH06_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HEG1076866.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            68914..71187
                     /locus_tag="SCH06_000261"
     CDS             68914..71187
                     /locus_tag="SCH06_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEG1076867.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            71225..72271
                     /gene="holA"
                     /locus_tag="SCH06_000262"
     CDS             71225..72271
                     /gene="holA"
                     /locus_tag="SCH06_000262"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEG1076868.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(72360..72614)
                     /locus_tag="SCH06_000263"
     CDS             complement(72360..72614)
                     /locus_tag="SCH06_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEG1076869.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(73014..73283)
                     /locus_tag="SCH06_000264"
     CDS             complement(73014..73283)
                     /locus_tag="SCH06_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076870.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(73753..74208)
                     /locus_tag="SCH06_000265"
     CDS             complement(73753..74208)
                     /locus_tag="SCH06_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HEG1076871.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(74346..76274)
                     /locus_tag="SCH06_000266"
     CDS             complement(74346..76274)
                     /locus_tag="SCH06_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEG1076872.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT        24780 a        13199 c        16595 g        21878 t
ORIGIN      
        1 ataaaattaa aaatgttaat acgtattagc aaaataaaag ctttttttat tgtgaataaa
       61 tgaacataat taggaggaga aagatgaact tatttgacat ttttcgatcg actttgacag
      121 atatgtcgat tgtcagtgca atcacttcaa cagtttttat tatattatta gggtttgttt
      181 gtagaaaaaa ggggattttt tctgaatctg ttggaaaaat tctatcgaaa gtcgtcttaa
      241 cagtggcttt gccagcactg gcatttcgag ctttcatgca agatatcaat acagaattac
      301 tgatgcaagg aatcaatgtc ttgatttggg gattagttat ttatattatt cttattctag
      361 tttcaaaacc ttttttctta agctataaag gggataagca aacaacgttg cgtgtcctga
      421 cgatctttgg ttctacgacc tttttcggaa cgcctatcgt cagtgcgatt tatggtcctg
      481 tcggcgtgat gtattcctca attttcaata ttggctaccg aatctttttg tattcttatg
      541 gatacataaa aatgagtggc ttgaagatgg aagctaaaaa tatcaaagcg atgttcgtca
      601 atccaatcat tatcgctact tttgccggcc ttttcatttg gctgttccaa gggtatctgc
      661 cacaagtgtc agttacaggt gcagaaggag agataagcca agtagcgttt ttgcgaattg
      721 accagactgc accgtggcta tttcagccga tggattattt agctggttta agttcaccat
      781 tggcgtggct agcaatcggc gcaacattag gtgaagtaag cttcaaaaaa gctgcatctg
      841 aaaaaacttc atggtattac agtctagtca aagtggtatt tgtacctgca ttgaatatcg
      901 tgattctagc agttttgacg gcaacgaata ttctaccagt caattttgaa gcactggcaa
      961 caatcgttat catgatggct acaccagctg caacagtggc agcagcctat gctatcagtt
     1021 ttgataggga ggcactttta gcctccaatg catccttact gtcaactatt tttgctgtgg
     1081 tactgacacc tgtatggatc gttgtattac aaatgattca tggcataggt ttattttcat
     1141 aagaaatgga ggaagaaagt atgagaatcg catgttacgg tgttcgtccg aacgagatag
     1201 atttttttga aaaattgaat atttaccatt atgatctcag tctttatgaa gaactgttga
     1261 cacatgacaa tatcgtgtca gcaaaggacc atgatgctgt attgttgagg ggaaattgta
     1321 tagcagatga gaccaatctt gcaaaaatgc aggaatatgg gattcgttat gtttttacac
     1381 ggactgtggg agtcaatcat atcgatctac aagcggcagc tgattttggt atgacagtag
     1441 cccgtgtacc atcgtattcg ccaaatgcga tagcagagtt atctttgact tttgccatga
     1501 tgcttttgag aaatactgcg tatacgacga tccgaacatc tttcaaagat tttcgagtgg
     1561 atgagcaaat gtttagtcgt gaaatcagaa attgcacagt agggatcata ggaacaggca
     1621 ggatagggtt gacggaagct gttttgttta agggactagg agccaaagtg atcggctacg
     1681 atattcatca gacagaagct gctaaaaaag tattgacgtt ccactcgctt gaagagttat
     1741 tagccaaaag cgatattgtc agtattcatg tacctcatat cccaggtgaa aacgatcaaa
     1801 tgatcaatga aggattttta gctcaaatga aaaaaggtag catcttgatt aatacagccc
     1861 gtggagagct tcaagataat gaagctattt taagagcttt gaaaagcaat catttagctg
     1921 gttttgcaac cgatgttttt gcaaatgaaa cagaggtttt tttccgatcc ttcaagccat
     1981 gggagacgat tccagaccct gctatccagc aattagtaga aatgtaccct agagttcttg
     2041 taaccccgca tgtaggttca aatacagatg aggcattatc aaatatgatt tcgacaagtt
     2101 tcgagaactt tcgtgaaata atagaaactg gaaaaacgaa aaatgaggta tctcttccta
     2161 aagcccgtca attaagataa gaaaacatgg atattcgtca ataaaatgtt taaaaatagt
     2221 ccaagtaaac agttgttact tctgtatact tggactattt tgtatgggat aattcgatga
     2281 ctcaacagta atctgtgagc tttttccgcc cattctttgt caattcataa caggttagcg
     2341 gctggccgat ttccaaatat ttgattcttt cgttcaatat atcttgttct actaaaaaat
     2401 tcaaatattt cttgacggat atacgtgaca gtgagctttt ttgagccagt tcttttgttg
     2461 aaaaaatagt atcttctttt agaataaatg cacttatttt ttttaaagtc agttttgaca
     2521 gacctttagg caaatcgatg aatgatggta tttcgtgaat gggagtggtg tggttgaata
     2581 cttgatcgat caatttctga tcggcttttt cagtcgtttg gattgtctga gagaaagcaa
     2641 gatacttttc gatcgccagc tgaaaacgtt gcaaagtgaa cggtttgatc aaataatcta
     2701 aggcaccgta gcggatcaca ttctttatgg tttcgatatc atctgcagca gtgatcaaaa
     2761 tcactgggat atcatttcct tgctgtctaa gccaagataa aaaatggata ccactttcgc
     2821 caggcatgta tacatcaagc agcagcagat ctgcgttttt ttgtctgaaa tatttttttc
     2881 cttcttctac atttctgaaa ctttcgatta cgttcatatt agggatgctt tccacaaaag
     2941 tacgattcaa ttctgcaacc attggatcat cttcgattat caggacattt gtcatcattt
     3001 tgatcttcct tttttggtaa ttctagatag acgattgtac cgccatttgt ttgtttggaa
     3061 aattctaaaa atccaccgtg gcgtttgacg attgaatgga tgagattcaa tccaaaccca
     3121 cgattgattc ccttcgtcga aaaacctagc gtaaatattt tttctgagat ttcttctgat
     3181 atcccgacac cgccatcgca gacggtcacg atgaatactt cagcttctgt gtcatagttt
     3241 aaatgaatcc ggacctgtcc gtttctttca tgtttttgta gcacggcttc ttttgcatta
     3301 tcaagtaagt tccctaacac ttgcaaaagt gaatggatgg agtcatccat ctccatttta
     3361 gggataaaag aatcgctttc taacagcatt tcaacagatt gttctttggc ttcgtttatt
     3421 ttgcctaata aaaaaccggc aattgcaggt actttgatca gacttgagac ttggccaatc
     3481 tcttttttat aattttgatt tagctgctgg ataaaatggg tgacttcttc atacttcttc
     3541 aaatcaatca aaccagaaat gacatgaagt ttattcatga attcatgggt ttgagctctc
     3601 atggagttta tatattgttt cgtcccccca agctcctcca ttaatttcat tacttctgat
     3661 cgatttcgta aagttgcgac tgctcctaaa aaacggtcat tgctaaaaag aggtgtaacg
     3721 ctagaaatag tttctatccc atttaaatac atggattgag tccgaacggt cgtttgatgc
     3781 tcaatcgtct ctttaaacaa aacgtcatat agattatcac tgattttttt cctacttcga
     3841 aatccaatag ctgctctgtt tggtagaaaa tgttttttgc aggtgtattg atcaagagga
     3901 tagttttatc agaagagatg gctaagattc cttcatctac ttcattttcg ataatcgttt
     3961 tttcacttaa ctgttctgct atttcttgtg gttcaagtcc aagcagtact tttttcattt
     4021 tttgggcaag aaaaacggcg cctatgatgc ctacgctaag tccaataatc aatgaaaaaa
     4081 caatcatttt ttgtccatct ttgacttgat tgtcaatcgt gttgtttgtt aagccaacac
     4141 aaactgcacc aataatctct tgatcataat aaatagggac gaaatagcgg aagccgaacc
     4201 ctaacattcc ttctttttca gagaaaaatt cttgtcctcc aatcactttt ttcacatctt
     4261 catgacttga gaaaggaaga ccgatgtaac ttgggtctgc gtgagaatat cgaatgcctt
     4321 cagggtccat gacaacgata aaatctaaat tcgatgcaat catgatttca tttgttattc
     4381 cttgaatcgc atgtgtcggg tcaccagtct gcagcttttt ttggatgagt ttatcattgg
     4441 caacgatttt agcaatgcta gagattttat ctgacacact agatcggttc atcgaaagaa
     4501 taaaattcct gatcaatatg gcagaaacaa tcaaagaaac gaatgtggag aaacaaacga
     4561 caaggatgat cgtgttctgg agctttaatg gttttttctt aaaaaaagga aacataggct
     4621 acctcgaaag aatttattgt gaaaatttta acatgaaaac aaaaatttaa caaattgtca
     4681 acgataaaca caaccttcct ataaaaaaca ccactgagtc ggtaaaagaa gctatacaga
     4741 attttcaaac attggtatga tagacgtaga aatggaagga ggcgtgtata tgataggggg
     4801 aatcgcactt gagacgattt attggtatac attgctgatt tgtgcaggat tggcagtcct
     4861 attgattatt tttggagatg tattcgattt tgatggcccg cttgatccga tgcttattat
     4921 cccttggtta actttcacaa gcttatttgg ttttctaggt gagcgtttaa cagatcaatc
     4981 atctttattt ttatttattg ctagtggagg catatcgata gtgttggtat ttttgcttaa
     5041 tttctatata ttgatgccga tgaaacatgc cgaatcaacg atgtcgtctt ctgaaaaaac
     5101 tctggaagga caagtagctg ttgtgatcac accgatccct gtacgaggta tgggagaaat
     5161 tcagttgaaa agtgttaccg gttccattag tcgtccagct tgtttttaca gcccccaaga
     5221 acagacagct gagcggggaa cgaaagtatt gatcattgag atcaaggaaa gaatctgtta
     5281 tgtcatgcct tatgaaagca tgataaaagc ttaaaggagc gtgtgttaaa tggaaatacc
     5341 agttgttttt atcgcgatcg caatcgcagc tttgatttta ctgatgttgc tgatcgtctt
     5401 tgtagcgaag taccagacag caaaaccgga tgaagcgttg atcatcagtg gaagttattt
     5461 aggaagcaaa aatgtgcaca ttgatgaaag caataacaaa atcaaaattg tgcgtggagg
     5521 tggcgcattc gtcttgccag tttttcaacg ttcgaatcgg atcagtctat tatcgagtaa
     5581 attggacgtc tccacccctg aagtgtatac cgaacaaggc gtaccggtga tgtgtgatgg
     5641 tacttcgatc atcaaaatcg gttcatctgt agaagagatt gctacagcag cagaacagtt
     5701 tttaggcaag acaagagaag aactggaaaa tgaagcaaga gaagtattag aaggacactt
     5761 gcgctcgatt cttggttcta tgactgtaga agaaatctat caaaatcgcg ataagttcag
     5821 tcaaagcgta caagaagtcg cttctgtaga ccttgcaaaa atggggttga tcatcgtttc
     5881 tttcactatc aaagaggtca gagacaaaaa cggttatctt gactctttag ggaaaccaag
     5941 aatcgcccaa gtcaaaagag atgcagatat agcagaagcg gaagctctaa aagaaacgcg
     6001 tatcaaaaaa gctcaagcag aaaaagaatc acaagcagct gaattacagc gacaaacaga
     6061 gatcgcagaa tcattaaaag aaaaagaact gaaattagca acctacaaac aagaacaaga
     6121 tgttgctaaa gcaaaagcag accaagccta caatttagaa agtgcccgag cacaacaaca
     6181 agtaatcgaa caggaaatgc agattaaaat cgtagaacgc caaaaacaaa tcgaactgga
     6241 agaaaaagaa atcacacgtc gtgaaaagca atatgattcg gaagtgaaga aaaaagcaga
     6301 tgccgatcgg tacgctaaag aacaagaagc acaagctcaa aaagtcaaag aagtgactga
     6361 agccgaagca gaacgattcc gtgtggaagc actggcagaa gcggaagcca ataagacacg
     6421 tttagctgga caagcagaag ccgaagcagc actagcaaaa ggaaaagcag aagccgaagc
     6481 aaaacaaaag atcgccaatg ccttcaagga atatggcgaa gcagctgtct tgagtatggt
     6541 tatcgatatg ctaccgcaat tgatgcgcga agcagcacag ccgctaggaa atatcgaaaa
     6601 aatctctgtt gtcgatacag gaagcagttc aggagaaacc agtggagcga accgagtgac
     6661 aaattatgcc acaaatttgc tttcttctac tcaagaaaca ctaaaagcga caacaggact
     6721 tgacttgaag gaaatcgtag agaatttgtc gacacgtggg actactagcc aagtaaatat
     6781 gtatgaagcg ccaaaagagg cagaacaaaa ctcgatgaag gaagaataaa gtagtacact
     6841 tcaccgttca atcaaaaatg gaggaagact ttttaaagtt cttctctcca tttttttatt
     6901 ttattgcaaa agaaaattag tcctcgctat ttttcttttg tttttggatc ttagcttcta
     6961 tctcttgtaa atttgttctt agcaatcgtt ctttcttttg gagttcgacc aaatcttctg
     7021 atagttcttc cttcttttct gtttcaggag gacgaagaaa gaaattgata ccgattgcaa
     7081 tgaatgtccc tataaaagta tctagtacac gttggatagc atacaaagcg gattcgcctt
     7141 gagggatgct caacgcaatc agcaacaacg tagctattgc ggaaatgata ccggaattat
     7201 tgttaatacc atctgacacg acgatcacaa taataactag aataggaagc aagatcaatt
     7261 ctaccaaaaa atcattgtga aaatagcttt tgacaaaaaa ataaatgata gctaatgtac
     7321 cacctaatgt attgccgatg atcctagact ttccaaaaga aacggttgta gtcaagtcct
     7381 gacgcaaaga aaaaacagca gataatgcag caatcatcgg gattcctcgt tgagtcaaat
     7441 gaaaaaacaa gatacataaa aaaacagcta aggcactttt gatcgtacgc atacctagtc
     7501 gaaaacggcc aaattgcata gagattctcc tttttggtct ttttactatc atacctaaac
     7561 ttttgtctga tagctagttt ttcattattc aagtataatt aaaataaaaa agggggaagt
     7621 aaatgcgtat aggaatgcga acagtcaaaa cagtgatcag tgtcttcttt tcgatggtca
     7681 cagcgggtag cttatcgctg ttgtattggc cagctgcagg gatcattgca ttattaagtg
     7741 taggaaatac caagcgctct acattgcgta cgggcatgaa tcgaatcgca gcctttatat
     7801 tagctacggc aacagcactg ttcagttttt ttgctgttgg gtatactatt tttggcttca
     7861 gtcttttttt attcctgttc atcccgcttg cctctcgctt caaattaacc gaagggatag
     7921 tagtaaattc ggttttggtc actcattatt tagtggagga aaacatgtct tggcagctga
     7981 tcggcaatga agcgggatta atggcgattg gattagtatt tgctttgctt gcaaatgttt
     8041 acatgccaga tcgtacgaag cagctgaagg aaaaccaaat acagatcgaa aaagaatttc
     8101 gaaatatttt gagacaaatg gcagaatttc ttttatcaga aaataaagaa gatgtgcaga
     8161 tcaaatgcga acatttactg acattcattc gcgaaagcca agaagatgcc agagaacatc
     8221 aagaaaacta ctggctcaga cagccgctat actacgaaac ttacttctct atgagaagag
     8281 cacaggccaa tgtgattaaa gacatgctgg aaaatctaga gagaatccag caaccagctt
     8341 attatggaaa acatatctat ggtttattga tttatactgc agaaacattt tcagagtcaa
     8401 atgatggcag acaaatttta acacgtattg aagaagttta tgtattgtat cggcaaatgc
     8461 ctctgccgac tagtcgccct gaattcgagg atcgagcaga attgttccag tttttgcagt
     8521 cttttaaaag ttttattgaa atcaaggcag aattctccca acaaaaaatc caaaaataga
     8581 ggttgtgaat tcagctaata ttcaggtcaa aaagctgatt tcacaacctc ttctttaaac
     8641 ggtgttctcc tgtcaactcc tcggtcacaa gtcacaatat tcaacaaaca tgagaagctg
     8701 ttttttgaaa ttgctccttg tgactcggag ctgaacggta ggctcacaac ctctttctta
     8761 aacggtgttc aaaagctttc ctctgcggta ataagtccag ccaaacgaaa aataggagga
     8821 gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca caacctttta
     8881 aaattacata tttttccata gaacttgcat ttgatccaag atttcgatga catcttttgt
     8941 caagaagaga gagcgattgg gcaagtcacc ttcaatcatg tgtaccatat tctttatttc
     9001 gtaattcatt gcttcagatg tattcccgct ttcgatgaat tcctttgtac catctgtaaa
     9061 taagatctcc gcacgatcag cacgcgggta atcagcaatc gtcacataac cgttctcaaa
     9121 ggcaacgata ccgacttttg gcatttttgc ctgaaaagtc aagctgacag cagcaagttc
     9181 attttctttg ttacgcaaga tagtgacgga ttgttcgtcc acgcctgttt caaaaggaac
     9241 cattgtagag gcaactactt caggttgaga gctcaaaaag aaacgagcga aagatacagc
     9301 atacgtaccg atatccaaca gagctcctcc agctaattct ggattgaaga accggttttt
     9361 agggtctggt tctttgtaac tgccgaaagg tgcttggatc atttttaaag cccccagttt
     9421 tcctgtatcc attattgagc gtaactgctg ataaagtggc atgttgaaga ttgtcatcgc
     9481 ttctgctaag atcaaattct tttcttctgc taagcgcata gcgtcagcca gttctttttt
     9541 attcatcgtg atggcttttt cacatagaac gtgtttgcct gcttccaatg ctgccaagat
     9601 atggtcgata tgctgtctat ttggtacagc aatgtacacg atgtcgattt cagcatcgtc
     9661 taacatttct tgatagcttc cgtaagcttt tggaatattg taacggtgag cgaagttttc
     9721 cgctttttct gaagttctgg aagcaactgc tgttagttcg ctcgtctctt gattgaagct
     9781 ttcggcaaac tcatgtgcga tggtaccaag accaacgatt ccccattgat attttttcat
     9841 ctgaaaacgc tccttcatag ttggattgag tttcttgtct gtctattatt ataacaaaaa
     9901 tcacgaagaa taaagaggag aggacttgaa acattaaaaa aaatgaaagc agcgatttaa
     9961 gaggtgcttt ttgatcaaaa cttaagtaga atagttaaaa ggaggggata aacgtgcatc
    10021 aagtatatat tgatcttatt atgagtgtat tattagaaca gtttgaaact gaaaaaaatt
    10081 ttttagatga atacttgctg atcagtccag aacaatggca aaaatggaaa gatggcgaga
    10141 aaaatctgcc atctgaagcg atgcagaaag taaaaaatct tttcactgat tatgaatgga
    10201 tgctaacgca aaagattttg cgtcaaacga ttatttttcc cgaaaaacga aacgttgccg
    10261 ttgcagagta caagcaaatc aaaacacgca tcgcgcaaaa atggcttagc agcaaagcag
    10321 caaaagtcga gctgatccct ttgaaaaata atcagcaggc tggtagatac cttgacttga
    10381 aagtaagtat tcaatatgat gaatggggct atgatgatat tttgaatttt cgtctgccag
    10441 cagatgttca aaaacagatc gaaggagaaa aaatcgaact tctcgattgg gtgaatgaaa
    10501 atctggaaga aacttacgtt catgaggcga atggggaacg tgaagaacaa cgaaaggatt
    10561 tttcaagtga ataaattttt aggatttgga gcagttgtga ttatgatcgc agcaatgggc
    10621 tatgttattt ttagcgatga tgattcgcat gttcaagccg gcaatcaagc agtcgaacga
    10681 acaagcacca aaacaactgc tagtaaagaa aagaacagtc aaacaaccag cagcaaggta
    10741 aaggacaaag aaacaaaaga tcgtacgtcc aaacaattgc cagatgttaa aacagacgat
    10801 tggaagctag ttttggttgg tccagatcac aaattagaaa aagaaattga tgagtctact
    10861 caattggcat cattaagtaa cggatacttg atcgacaaac gcattgctcc agaatatgaa
    10921 gcatttgcca aggctgctga agcagctgga tttccattag tgatggtctc agcttaccgg
    10981 tctgtatcat cccaacaaca agttttcgaa caaaatgtcc aagatgtgat gagtcgtcaa
    11041 ggtgtatcag aagaggaggc gacaaagatt actaaagaaa cgattacgga gccaggatac
    11101 agcgaacacc acacaggtct ggcagtcgat gtcgtcgatc aaaactggta caacagttat
    11161 ccttctactg tattggatgc aagttacgga gatcagcctg gagctaaatg gatcgcagat
    11221 aatgctgcgc agtatggatt tatcgttcgt tatccaaaag gacacgaaga tataactaag
    11281 atcacatatg aaccttggca cttacgttat gtcggtaaag aaaacgctga gtatatcacc
    11341 aaacaccaat tgacgctaga agaatatctg aatgaattaa atgaaaagta ggaattgatc
    11401 atggcgaaaa aaaagtggaa aaagcaaaag cgcaagaata tccgttggcc agcagtggtt
    11461 gccggtgtag cagtgatact cttagccttt gttttttcct tgaagaatct gtcttctcct
    11521 tttactgata atcagcaaga aaatgaagcg caatcccatc agcaatttat tgaacggctt
    11581 gttccgcatg cccaagaact acaagatggt tatggagtgc ttcctagtat cattttagga
    11641 caagctatat tagaatcaaa ttggggaaaa agtaccttgg ctagcaaata caataatctt
    11701 ttcgggatca aggcttatgg ggatcagaag aaagtaagcc tggaaacaaa ggaatttgtt
    11761 aacgaagaat ggataactat ccaaggagac ttcaaagtgt atgattcatg ggaacagtcc
    11821 atggatgacc atacacaact gttcgtccaa ggagtagatt ggaatcctgc gctgtatgaa
    11881 aaagtgatta cggccaccaa ctatcaggaa gccgcacaag cattgcaaga tgcaggttat
    11941 gcgacagacc ccggttatgc gcaaaaaatc atccaggtca tcgagacgta tcaattgaat
    12001 cagtatgacc ggagatagca aaggagaagt ggctgatggc agaacaattt acgccagaaa
    12061 tcatgacgga attgagaaaa gatatcgtaa gagtaccgga aatcatttta gaagcaagcg
    12121 ggatcaagat atttggaaaa ttgatccgtt cgatcatctt tactacggat attgcgatca
    12181 tacgtaatac aaatgcgaat gcagtaattg ctgtgtatcc ttttacacct catccagcga
    12241 ttactaaaag cattattgag gcagctgaca ttccagtttt ctccggtgta ggtggtggtt
    12301 tgacacaagg tgctcgttct tcctacatga gcatgttcgc agaagcgcaa ggttcgttag
    12361 gggtcgtttt gaacggtcct acgcctttag agacagtaaa agaagtttgt cgagtagttg
    12421 atattccagt tatcagtacg gtaacgtcga aatatacaga aatagatgaa aagttagcag
    12481 ctggtatttc gattatcaat atcagtgcag gtaaagaaac tgcagaagca gtacgccatt
    12541 ttcgtaaaaa atatcctgaa cttcctatca ttgcgacagg tggtccaacg gaagaaagta
    12601 ttgctgagac cattcaagca ggagcaaatg ccatcacata tacgccacca agtagcggag
    12661 agctttttag tcgtaaaatg gaaaaatatc gggaaactga gaaaaagaat catgaataac
    12721 aggtgagaat caaaagacga ggaagagcag atagtggctc ttcctcgtct tttgtactcc
    12781 agtactattt gttcagaatt caaaaaaaag agaaattttt ttgttttttt acctgtaatg
    12841 tacataagaa gagttaaaac cttttgttat tattagcatt ctaacaaaaa aatgtcttga
    12901 tttattgaag cgctttctat agaatgaaaa acgaataaaa actaaaaaag gcacccgaca
    12961 atttagtagc agctaaattg tcggggcttg aaaagtcagc gggaactgac caatcaagtt
    13021 gccatagtca atgcttgtgc atcgacgtgt atattgtacc taatttcata cagaattact
    13081 agttattttt ctgtttttta gggaagagcg cacacgaaga agcatgctta tttagctatg
    13141 tcaaggatat tgggcagttg tctgatatcc ttttttcttt gcgtaattat cctcccatca
    13201 ttgaagcaag aagtgttttt agcgatgaaa gaagaatcag cactatctaa tttttcttga
    13261 aagtattgag ttgttcatcc taggcagaac gataaggcaa gtcttggttt ttattcccct
    13321 tgaaaaagat cgtttaataa atatgttctg tataaaaata cagtatattg aaaaataaca
    13381 atggaagtag aggtgcagag aatgaagaaa agaatgagaa tcatcttagc tttaagtgtt
    13441 atgttattct tcttgacggc ttgtgggcaa gaagatgaca aaaaaatcac gctgaacatg
    13501 gcttggtggg gttcgcaagt ccgacacgat gcaacagtaa aagtaatcga gctttatgaa
    13561 gaaaaaaatc cccatgtgac gatcgattat gaattttatg attatgaagg atattacaca
    13621 aaattaggta cactagcagc atcagatgat atctgggaca ttttccaact gaacaatcaa
    13681 tttcctcaat acatcaatca gattgaacca ttagatgaat atgtggagca agggataatt
    13741 gatatttcta atgcagatga atcctattta gcaacgacga cttacgacgg gcaattagtt
    13801 ggactgtcta acggggtgaa ttcgtttgcg attgcttaca ataaaaatat atttgaacaa
    13861 ttaaatatcc ctgaaccagc ttcaaattgg acatgggatg aatttgaaca aatcagctat
    13921 caaatcactg aagaattagg aatctatgct atttcaagat tcgaagattt tatagctggc
    13981 tgtattattc aaataccaca agttgagaaa ggattgaatt tttataatcg ggaagatcta
    14041 tctaacagct tgggatttga aaatccagac tatctaacag attttttcca gctgcgtaaa
    14101 aatctggtag acaaaggggc ccatccagaa ccaggtggtg gagctgcaag tacgacggat
    14161 ctgtcttttc aggcggttag ggatagagaa gcggcaatgg tgtttctatc aagtaaccag
    14221 ttgacagaaa tattgtcagg ggctcctgaa gatatggaga ttcagttgat taatccacct
    14281 cgcagaaaag cagatggaga atctggtatc cctttacgtt cttcgcaaat gctgagtatg
    14341 gcaaaaagct cagcccataa agaagaagct gctaagttta ttgatttctt tcaaaacagt
    14401 gaagaagcca atgaaatttt aaaaggagaa cgtggtgtac caatcatgtc gaatattcga
    14461 gaacagctcg ctcgtgcaga tgatgcaact ttgcaagcga catttgatta tttagaaatg
    14521 atttccgata tggacaacgg cgaagtgaat gtctttgata gtgctttgaa tccggaaatt
    14581 caagaccaat acaatctttt agttgaaaaa gtcatttatg aagaagtaac agcagaagga
    14641 aggcatgaaa aaagaaaaac taaaacggtt cttggatcaa gacaatgtgg tcggttacgt
    14701 atttgcttct ccattcatcc taggatttct attgataaca gtgataccga tgatcttgtc
    14761 actttattat tcgttcaccg attatcgttt gggaaatcca gtctcatgga tcggcttgga
    14821 taattatata aagatgctga gtgatgcccg ttttttgaac tccatccgag tcacttttct
    14881 ctatgtattt gcatctgtac ctgtgaaact gatctttggt ctattgattg cttatctttt
    14941 aacgaggaat atcaaaggaa cgactttctt tcgttctttg tattatgtgc ctagtttgat
    15001 cggtggcagt atttctatcg ctctagtttg gcgggagttg ttttctaaaa acgggttagt
    15061 gaatattttc ctggaacgat taggcgcacc tgcgctttcc tggtttagcg atcaaaaact
    15121 ggtcatgatc cctcttgttt tgatgtctgc ttggcaattc ggttcggcaa tgatcatctt
    15181 tgctgcaggt atcaaagaga tcccaggctc gtattatgaa gcggcagaga tcgatggagc
    15241 gaacaaatgg cagacgtttt acaagatcac gttacctctt ctttcgccga tcattttgta
    15301 taacttggtt atgcagacaa tcgcggcgtt tatgactttt acgcaggcat ttatcattac
    15361 ccaaggtggt ccgaatgatg ccacgaactt ttatgctctt tatgtgtata accaagcttt
    15421 ttcttttaat tctatggggt atgctagtgc tatttcgtgg atcatgctgt tgattatggg
    15481 agctgtcacc tttctgattt tcaaatcatc aaaaaaatgg gtcgttgtgt gaatgagagg
    15541 aggaagaaat gaataataca gtaacgaaat ggtttcaata cggttttatt ttgctattag
    15601 gtctagtcat gatttatccg gtcttatgga tgatcgcagg ttcttttaaa acggatcaag
    15661 agattatgag tggttcgctg aatttgattc cagagacttt tcaatgggaa aattacgcaa
    15721 aaggatgggc ggggtttgct ggaatttcat tttttacttt ctttaggaat tcgtttgtca
    15781 tctctgcagt ttcgacgata gggacagttc tgagctcgac ttgtattgct tacgcattat
    15841 cgagaatcga tttcaaagga aaaagattct ggttcgtcgt catgttagta acgatgatga
    15901 ttcctgcaca agtgattttg attccgcagt ttattattta caatcggctg aatttggttg
    15961 ggacgtatgt gccgctgatt ttaccacatt tttttggaca agcatttttc atttaccaga
    16021 tcatgcaatt catggtcagc atccccaaag agttagatga atcagcgatt attgacggat
    16081 gcagcaagta tagtgtcttt accaaaatta tttttccttt gctgaaacct tcgatcatca
    16141 cgacgatcat catccagttt tattggaaat gggacgactt catgggacca ttgatttatt
    16201 taaacaagcc gagatcttac acggtatcga ttgccatcaa attatttgca gacgctggat
    16261 ctagtacgac ttacgcgagt atgtttgcga tgtctacgtt gtcgctgcta ccggtttttc
    16321 tgattttctt attcttcaat aaatatcttg tccaggggat cagtacaagc ggtctgaagg
    16381 gctgaatatg aaaaagccaa tagaagagat gtttctttac aagctcaact actatgtctg
    16441 tcggattttt ttaaccagtc ttatcagtaa tgctcttttc gctttagttc taggatgttt
    16501 gttcacttta ggattagtgc tgtctgctcg tgttgtctat ctgatttatt ttttgatgat
    16561 gtatccttct tattatctat ctgtccatta cttggcagaa aaaaaggtat gttggaggaa
    16621 agggaaaatc aaacggatgt gtttcatcat tacgttgttt cagctgtttg tcattatttt
    16681 tgcagttgat tggtatttat tagtgggaaa gattggagct tggtatctga ttccttttct
    16741 attgtgtctg ttgctttttg tatcccatag tttttttagt acgctaattg atatctgcaa
    16801 agaagataaa gcagatagtc ttgtttattt gatcaaaagg aatatctggc tgttgtcaaa
    16861 aaacgtcaag gggtttctgt ggtatttatg ccttttgtat ggactgttct ggtgtataca
    16921 gcctgatttt ttactcactg cattactgta tccagggctg ccatttgtca cagtattttg
    16981 cttaaaagaa aaggagaatg actttaaatg aagaaaaaat atgtacaagt cggacttggt
    17041 gggagagcgc gtttttttta tgaggcaatt gcctctacgt atcatcaaac ttgtgaacta
    17101 gtcggttttt gtgatgtatc tcaaacaagg atggattatg caaatcggat acttgtgaac
    17161 aagtatggac agaaaaaagt aaagacatgt atgccatcac aatttgagca actactggat
    17221 gacgtacggc cggctgaagt cattattacg tcagtagatc gaacgcatca tgattatatc
    17281 attcgtgcaa tgaaaaaagg atatgatgtt atttgcgaaa aacctctgac tatcgatgag
    17341 gaaaaagctc aagaaataat aacggtccaa aaacagacgg gaagaagcct gcgagtcact
    17401 tttaattatc gttatgcacc gtatcacacg aagataaagg aactgataga aagtgatgtg
    17461 attggtgatg tgttttctat ccacttcgaa tggctgttaa atacgcaaca cggggcagat
    17521 tatttcagaa gatggcatcg aaataagcac aatagcggcg ggcttcttgt tcataaatct
    17581 acccatcatt ttgatctagt gaatttttgg ttgaacagcc gtccccaaaa ggtatttgca
    17641 ttcggtggat taaactttta tgggatgcat aatgcggaga aacgcggagt agaaatattt
    17701 tacagtcgat gctatggaag cgaactagct aaagctgatc catttgctat agacctgtca
    17761 gccaatgagg aattgcgaga aatgtattta gaagcagaaa aagacagtgg atatattcgt
    17821 gaccgcagtg tattttccga tgatatctct attgaagata cactaggcgt aacggtcaaa
    17881 tatgaaactg gtgcgatttt gacgtattcg ctaaacgcgt atatgccgtg ggaaggattc
    17941 aatgtttctt tcaatggcag caaaggacgg atcgaaatga aagtgatcga aaagtcttac
    18001 atcaatgcag gtggagataa aaaggatgaa ggagcagccg ttcttcagtc catccatgtc
    18061 tatccgatgt tcggtgagcc atatgaggta atcgtcgaac aagaagcggg cggacatggc
    18121 ggaggagatc cgcgtttatt agatgatcta tttggtgaag aaaaagaaga agatccgtgg
    18181 aatcgggcag caactcacgt agatggtatt ttgtcgattt tgacaggaat cgcagcaaat
    18241 cattctattg cttcaggaaa agcagtagtg attgacgagc ttgtcagctt aaaagaataa
    18301 gaatagattt acggaaatta cttcccgtag tttataaaat cttgccttat tgccgatagg
    18361 ctgtcttttg aacactattt attcggaaaa aggggctatg acatgctttt tgtcatgcct
    18421 tctttttatg tgggctgctt ttttagatag gagaaaataa aaataactat ttaaacccga
    18481 acaaaaagga ataatgcatt aaaaatcatt agattttaca aaaaaataag taaaccacgt
    18541 tgtcagtttc agaaagtagt gttagactgt tttcaatatt tgaaacaaca ttttttattc
    18601 aaatatggca aactgccttc acgtgcaaaa cagttgcaag aaaatgaatt tacactatta
    18661 ttagttttac atacctactt atatatcgtc ataatatgga tgacagtttc tagccagtac
    18721 cgtaaatgct ggactataag taaaagattg gctatttcac ccttcttttc ttatgataaa
    18781 gtggagggtg tttttcttta acagaaacat agtaggtttt tgcacaaaag cggttatttc
    18841 ggtattaata aatgataaag gagcaaataa agtgaaagaa ttagttgaac gtattcaaaa
    18901 agacggacgt atattaggcg agggcgtatt aaaagtcgac agcttcgtca ctcaccaagt
    18961 agaccctgta ttgatggaac aaatgggaaa acggtttgca gaagtattta aagaacaagg
    19021 aatcacgaaa gttgtgacca ttgaagcttc tgggatcgca ccagctttat ttgctgcaag
    19081 agaattagat gttccaatga tcttcgctag aaaagcaaaa agtttgacga tggatgaaga
    19141 attattgaca gcttctgttt attcttttac gaaacaagtg acaagtacga tttctatttc
    19201 tcgtaaattt ttatcttcag aagacaaagt attgattatc gacgatttct tggcaaacgg
    19261 acaagcggca aaaggattga tcgaattatg ccagcaagct ggagcgcaag tagaaggaat
    19321 cgggatcgtc atcgaaaagt ctttccaaga tggacgtcag ttacttgaag aaatgggatt
    19381 gagagtcgtt tctcttgcgc gtattgcttc cttgacgaat ggacaagttg agtttcttga
    19441 ggaggacgca taatcgtgga aaaagaaaca caaaatggaa aagctgcggt tttagggctg
    19501 cagcatctgc tagcgatgta tgcaggagca gtagcggtgc ctcttttgat cggtacagga
    19561 ctaggcttta atcaagaaca gatgacttat ttgatttcaa ttgatatctt tatgtgtgga
    19621 ttagcgacat tattgcaatt gacagttaac cgatttttcg gaattggctt gcctgtcgtt
    19681 ttaggatgtg cgatccaagc agtagctcca ctgatcttga tcggaaccaa tgaaggagta
    19741 ggagctatct acggatctat tatcgcttct gggatctttg ttgtgttagt ttctggtgtc
    19801 ttttctaaaa ttaaaaaact attccctcct atagtaacag gaacggttat caccgttatt
    19861 ggtttgactt tgattcctgt agcaatcgag aaaatgggtg gaggtaatgc aacagcagct
    19921 gattttggtg acaaaacaaa tctgctactt gcatttgtga cgattctcct aattgtaggc
    19981 gtgcaaatgc tggcaaaagg gttcattcgt tcaatcgcgg tattgattgg tttagtcgga
    20041 ggaagcatct tagctgcttt catgggaatg attgatctga gcgcgattgg agatgcgccg
    20101 ttgttccatg ttccacaacc cttttatttt ggtaaaccaa ctttcgacgt atggtcgatt
    20161 ttactaatga tcatcatttc catggtcagc atggtagaat caacaggtgt atattttgca
    20221 cttggtgaca ttactgggaa aaatgttgga gaagaagaat tgaaaaaggg atatcgtgca
    20281 gaaggacttg ccgttatctt aggcggtatt ttcaatacat tcccttatac tggcttttct
    20341 caaaatgtcg gattggttca actttcggga atcaaaacaa gaaaacccat ctatttctct
    20401 gcattcttct tgattgtttt aggattattc cctaaaatcg gtgcgttagc acaaatcatc
    20461 cctgagccgg tacttggtgg aggaatgtta gtcatgttcg ggatggtggc agtccaagga
    20521 atccgtatgc tgttggaagt tgatttcagc aatgataaaa atctattgat tgttgctgtt
    20581 tctgttggat ttgggctggg tttcaatgtt acgccgacat tattcagtca aatgccgcaa
    20641 acattgcaaa tgttcactgg aaatggcatc gtaatgagta gcattacggc tatcatattg
    20701 aatttgatct ttaatggatt gaaaaaagat gaagaaatat tggaagaagc cttcaagaag
    20761 taatagagca aaagaaaggt tgtgaaatca gcgttttgac ctgattgtta gagaaacaaa
    20821 cggaaaaata gttcctcgta ttttgccgtt tgtttgagct aataccgagg gtcagctgat
    20881 tgaacaccgt ttatccataa aaaggaatgt gacctaactt ttgtcacatt cctttttttc
    20941 atctttaata aacacgaaca ataaaatgtt tttctttgtt aacattcgaa atttctttga
    21001 catcaaaaaa agtgattgtt aaaatatgaa tgtagaaaaa ctgggaggaa aaacaatgac
    21061 agcaaaaatc tctgtgatta tggggagtac ttcagattgg gaaacaatga aagaagcatg
    21121 tcaaatattg gatgaattcg gtgtgtctta tgaaaaaaag gtcgtttctg ctcatcgaac
    21181 cccagatttg atgtttgaat atgcacaaaa cgctcgaaaa aaaggaatca aaatcattat
    21241 tgcaggagca gggggagccg cgcatctgcc gggtatggtc gcatcaaaaa caactttgcc
    21301 ggttatcggt gtaccggtcc aatcacgaac attaaatggt ttggattcgc ttctttcgat
    21361 tgtccaaatg cctggaggag tacctgtagc tactacagca atcggaaaag cgggagcaat
    21421 taatgctgga ctacttgcga tacagatgct ttccatgtat gatttagaat tggaggctaa
    21481 attggctgaa agacgttcaa tgttggctaa aactgttata gaaagtagtg atcaacttgg
    21541 ttaaaccttt gttgcctggt tcaacgatcg ggatcgtcgg tggcggtcaa ttaggtcgta
    21601 tgatggcgat tagtgcaaaa gaaatgggct ttaaagtagg tgtgctggat cctgtgagcg
    21661 attgtccagc cgcacaagtt gcagattggc acattgaaag tgtctatgat gacacctttg
    21721 cgctgaaaga gcttgccaga agaacagatg tcattaccta tgaattcgaa aacgtcagtg
    21781 tagaggcgtt aaatgcgatt ttacccatgt catttattcc tcaagggaca gacttgcttg
    21841 cgattacgca agaccgcctg ttagaaaaat cttttttgga aacgaataac atcgtgattg
    21901 ctccttatgc aacgatcgtc agtccgacgg atatccaaga tgcgattgac gggatcggct
    21961 atccttgtgt tttgaaaacc actcgaggcg gctatgatgg caaggggcag tatgttttga
    22021 aaagtcgggc ggatctagct cctgccatgg accttttaag agaaggaacc tgtgttttag
    22081 aagcatggat cccgtttgaa aaagagattt cgatcatggt ggcaggaaat ggtcaaggag
    22141 atttcacgac ttttccggtc gtggaaaaca tccaccacaa caatattctt catgaaacga
    22201 ttgctccagc cgcgattgat caggatgtga tcgaggaggc tgagcgtatt gcccgtgtga
    22261 ttgcagaagc agtgagcctt tcaggtgttt taggggtaga aatgttttta acaaaaacag
    22321 gcgggctata tgtgaatgaa ttagctcctc gtcctcacaa ttctggacat tattctattg
    22381 aagcttgttc tatgagtcag ttcgatgccc atattcgagg tatttgtggt tggccattag
    22441 gagaaaaagt acgtttgata agcaatgcag taatggtcaa tgttttggga gaacaactgc
    22501 tggaaagcta tcgcttgatt gagaataagc cagactggca attccatttc tatggaaaaa
    22561 aacaagcaaa aaaaggtcgc aagatgggac atatcactat cttgacagaa gacatccagc
    22621 aaacgctgga agaaatcaaa caaacgaata tttgggatta gaggagaaaa aacatgttag
    22681 aacgttatac acgccctgaa atggggaata tctggacgga agagaacaaa taccgtgcgt
    22741 ggctcgaagt cgagatttta gcagatgaag cttgggcaga acttggtgaa atcccgcaag
    22801 aagatgtgaa aaaaattcgt gagcatgcat catttgatat cgatcggatc ttggaaatcg
    22861 aaaaattaac acgccatgat gtcgttgcgt ttacacgagc ggtttctgaa acattgggag
    22921 aagaaagaaa atgggtccat tatggtctaa caagtacgga tgtcgtagat actgcttatg
    22981 gctatctcat caagcaagca aatgatattt tacgggaaga cttgaaacgt tttacggaaa
    23041 tcattggcga aaaagcaaaa gaacacaaat atacagtgat gatgggtcgg acacacggtg
    23101 tccatgctga accaactact tttggattga aacttgccac atggtattca gaaatgaaac
    23161 ggaacatcga acgatttgaa catgcggcaa aaggagtaga agcaggaaaa atctcaggag
    23221 cagtgggaac gttcgcaaat atcccgccat ttattgaaga gtatgtatgt aaacaattgg
    23281 ggatccgtcc acaagaaatc tctactcaag ttctccctcg ggatctacat gctgaatatt
    23341 tctcagcgat ggcgcttatt gctacaagta ttgaacgttt tgcaacagag atacgcggat
    23401 tgcaaaaatc cgaaacacgt gaagtagaag aattttttgc gaaaggtcaa aaaggttctt
    23461 ctgctatgcc gcacaaaagg aatccgatcg gttcagaaaa tatggctggt ctagccagag
    23521 tggtgcgcgg acacatggtc actgcctatg aaaatgtcac attatggcat gaaagagata
    23581 tttctcattc ttcagcagaa cgaatcatct tgcctgatac cacgatttta ttgaattaca
    23641 tgttaaatcg ttttggcaat atcgttaaaa atctaacggt ctttcctgaa aacatgaagc
    23701 ggaatatgtc tgcaacattt ggtttgattt atagccagcg cgttatgctg aaattgatcg
    23761 ataagggaat gacaagagaa gaagcttatg atcttgttca gccaaaaact gcgtacgctt
    23821 gggacaacca agtgcagttc cgcccgctgt tagaagaaga tccaaccatc acatcggtat
    23881 tatctaaaga agaaatagac gatgcctttg attatcatca tcatttgaaa aacgttgacg
    23941 tgatattcaa acgagtaggt ttggaataaa gaagagtgag ttgcaaaatt caattaaaat
    24001 agaatagcaa aaataaccaa aaaagaagca gatccgttag cggttctgct tcttttagtt
    24061 tattatattt tcttatcaat aataggaacc tgattttaaa agcggctacc tctttaccgt
    24121 gcctctttac atacaaaaaa tagaggaatt aagcgtaaat ggcttggcta ttataactaa
    24181 aatgctggtt atggagatgt tgcagcaagt tttcgagaaa agcgtattcc atctcttgtc
    24241 cattgaataa gatctggata cgataatgat ttttgaaacg cttctgttca tgaatctgac
    24301 tgattgaaag ttcgcctttg tgttctgtct gataaagaaa agtcctttta cggcattcag
    24361 cacagcgctt ggttgctcgg cggatttttc ggaatgtata aaaactagta tctttattgc
    24421 ataaataaac gtctttgatc gacagcaaat cattatatag acaggaacgt tcttcagctg
    24481 ttaattctga taaaaaaagc tgaccttgtt ttattgcatc ttccatcggc aagtgcctcc
    24541 tcgaacccat tatccaaatt tttagttaat tctaatatac catcattaag tataaatgta
    24601 aacgcttgtt gatggtataa gattttcgtt tctgataaaa cacgaacatt aaaagaatct
    24661 aatgccttaa atgtacatat ttttgttgat ttataaaaag atgattgcta aaatttaaag
    24721 tgaaaaaacg aacaaaaaac gatgtatttg cttttaatgt aaataaaaag gagagacgta
    24781 catggagaag aaagaacttt tgtatgaagg aaaagccaaa aaaatatatc ttacttctga
    24841 tgagaacttg atttggatag aatatttaga tcaagcaact gcgttgaatg gcgcgaggaa
    24901 agaccagata agtggaaaag gagaattgaa taatcaaatc acaagtgcaa ttttccgtta
    24961 tctgactcaa agaggaataa aaaatcattt tattgaacaa ttgtctaaaa ccgaacaatt
    25021 agcaaaaaaa gtacaaatta tccctctgga agtggttatc cgaaatattg cagcaggaag
    25081 tttctcaaaa cgtctaggtg ttcccgaagg taaagaattc atcaaaccaa tcattgaatt
    25141 ctactataag gatgaccagt tggatgatcc atttatcaat gaagagcata tctatttctt
    25201 acaacttgca aaaccggaag aaatcagtga gctgaaagcc caagcgttgg ctattaatga
    25261 aattttgacc gaattatttg ctaaggtcgg tttggtttta gtagatttca agctagaatt
    25321 tggccggtcg aatggacaaa ttttgcttgc ggatgaagta acaccggata cttgccgatt
    25381 atgggatgaa cgtacgaatg aacatatgga caaagacgtt taccgcagag atctaggtga
    25441 tttgatccca gtctatcaag aagtatataa ccgtctatcg gaactaactg aagaaaagga
    25501 gcgagtatga tgtatttcgt aaaagtatat gtaacctata aagattcagt gttagatcct
    25561 caaggggagg cagtaaaaaa agcagtccat cgtatgggat atgaaacaat cgaagatatc
    25621 cgaataggaa aatactttga gatacaactt gctgatgcag aagaaccaat cgatacagtg
    25681 attgaaacga tttgtgacaa gctgcttgca aatgtaaata tggaaacata ccgatatgaa
    25741 atcaaaaaaa tggaggaagt ataacatgaa atttgcggtc atcgtttttc caggttcaaa
    25801 ttgtgacgca gatatgttat gggcagttcg cgagatcatg ggcgctgatg ccgaatttgt
    25861 acggcatgat gagtcctctt tagaaggatt tgatggggtt ttactgccgg gaggattctc
    25921 ctatggtgac tatttgagat gcggtgcgat tgctcggttt tctacaatca tggaagaagt
    25981 gattcgtttt gctgaagaag ggaaaccagt attcggtaca tgcaatggat tccagatatt
    26041 gacagaagca ggacttttgc caggtgtact gagacgaaat gagtctttgc attttatttg
    26101 caaaactgta ccattgaaag tcaaccccaa gacggccttt acttcagagt atgaagccga
    26161 cgaaataatc tatcttccag ttgctcatgg ggaaggaaat tatttctgtg acgaagaaac
    26221 acttcaagaa ctaaaaaaaa ataatcagat tgcctttact tataatgaca acatcaacgg
    26281 cagcgtggaa aacattgcag ggattacgaa caaagcaggg aatgtgttag gaatgatgcc
    26341 tcatccagaa cgtgcagtag aagacttgct aggatcagaa gatgggaaac ggttctttgc
    26401 ttccatttta aaaaacttcg gaaaggtgac cgtatagatg aaaacattga aagaaccgac
    26461 agctgaagag atcaagaaaa aaagaatcta tgccgaatgg ggattgactg atgaagaata
    26521 tcgaatgatc gaagaagata tcttaggaag aatgcctaat tatacggaaa ctggactgtt
    26581 ttctgttatg tggagcgaac attgttccta taaaaattct aaaccggttc tacgcaaatt
    26641 tcctactagt ggacctcatg tgttgcaagg ccctggagaa ggcgcaggca tcgtcgacat
    26701 cggtgatgga ctagcagttg tcttcaaagc agaaagtcac aatcatcctt cagccgtgga
    26761 gccttatgaa ggagctgcga caggagttgg cggaatcatc agagatattt tcagcatggg
    26821 ggctcgtcca attgcgttgc tagattcatt gaggttcggc gaattagata atccaagaac
    26881 gaaatattta ctagaagaag tagttgcagg tatcggcgga tacggcaatt gtatcggcat
    26941 accgactgta ggcggcgaaa ttgcatttga tccttgttat gaaggaaacc cattagtcaa
    27001 tgcaatgtgc gtaggtttga ttgaacacaa acatatccag aaagggcaag ccgctggcgt
    27061 cggtaattcg atcatgtatg taggtgcaaa aacaggtcgc gacggtatcc acggagcaac
    27121 ttttgcctca gaagaattta atcaagaaga agaacagcaa cgttctgctg tacaagtagg
    27181 cgatcctttt atggaaaagc tgctgcttga agcgtgtttg gaattaatct tgcatcattc
    27241 ggattctcta ataggtatac aggatatggg agcagcagga cttgtttcat ctagtgcgga
    27301 aatggcttca aaagctggct caggacttat attgacatta gatgaagtcc cacaaagaga
    27361 aactgggatg acaccttatg aaatgatgtt atcggaatca caagaacgga tgttgatttg
    27421 tgttaaatca ggagaggaag aaaaaatcca agaactattt cagaagtatg atctagatgc
    27481 agtcactatc ggtaaagtaa cagacgacgg gcaatatcgg ctatatcatc aaggagaaga
    27541 agtagcaaat ctgccagtcg atgcattagc tgaagatgca ccagtttatc ataaagaaat
    27601 gaaagaacca gctcgaatcg tagaatttca gcagttagct ccttatcagc cagttatcga
    27661 agaacctgga caagtattgc ttgatctgct gcagcaaccg acgattgctt caaaacgttc
    27721 aatctacgaa acttatgatt cacaagtaca aaccaataca gttgtccgtc caggaagcga
    27781 tgctgctgtg atgagggtta gagggacgaa taaagcgtta gctatgacca cagactgcaa
    27841 cgcgcgctat ctgtatttgg atccaaaaat cggaggacaa atagcagtgg cagaagctgc
    27901 tagaaatatt attgctagcg gtggtaagcc cttggcgatc accgactgcc tgaactatgg
    27961 ttctcctgat aaaccagaag ttttttggga attatcgact tcagctgacg gaattgctgc
    28021 tgcgtgtgaa acgttaggaa ctcctgttat ttcaggaaat gtctctttat ataatgaaac
    28081 ggatggtcaa gcaatctatc caacaccaat gattggtatg gtcggattga ttgaggatca
    28141 taaacatatc actactcagg aattcaaaaa atcaggggat ctaatctata tattaggtaa
    28201 gacgtttgca gattttgatg gcagtgaatt acaaaagatg cagcttggaa gaatcgaagg
    28261 tgtgatccga aactttgatc tatccattga aaagagaaac caagagttag tattgacagc
    28321 catccaaaac ggattgattg aaagtgctca tgactgttca gaaggtggct tggcaattgc
    28381 actggcagaa tcagctttca aacatcagct agggatatct gtacagtttg aattgtcctc
    28441 tgctcaatta tttgcagaaa ctcaatcaag atttgtgttg acagtcgcac cggaaaataa
    28501 gacacgattc gaagaaatga tgggagatgc tgctgtttta gcaggtaagg tgacggatga
    28561 agcgataatc gaaatttcag caactgacgg tcagatcaaa atagaaactg cagtagcaag
    28621 aaagtgctgg gaggatgcaa tcgtatgtct tatgaagtga agagtttaaa tgaagaatgc
    28681 gggatcttcg gtgtttgggg tcatccagac gccgctagtg tggcatactt cgggctccat
    28741 agtcttcagc atcgaggaca agaaggtgca ggtatcgtgt ccaatgatcg aggaaagctt
    28801 aaggggcatc gagatttggg gctgctttct gaggtattca aagatcaaag aaaattgcag
    28861 cagttaacag gagaagctgc aatcggacat gtacgttatg caacagcagg caatggaagt
    28921 gtggacaata ttcagccttt tctattcaaa tttcatgatc agtcgatcgg cttagcgcat
    28981 aatggtaact tgatcaatgc tcgttccctt agaaaagagt tagaggaaaa tggggcgatc
    29041 ttccattcta actccgatac ggagatattg atgcatttga tccgacgaag tgaagaaaca
    29101 gattttttaa ataaattaaa aagtgctttg aatgaagtca aaggtggctt tgcctattta
    29161 ttaatgacag aaacggcaat gattgccgct ttggacccaa atggttttcg tccattagca
    29221 atcggacaaa tgaaaaacgg agcatacgtg attgcctcgg aaacttgtgc attagaagtt
    29281 attggggcac gttttataag agatgtccag cctggtgaga tagtgatcat caatgacgaa
    29341 ggaatccaga ttgattgctt tacgaaggac acgcagcttt ctatttgttc gatggaatat
    29401 atctattttg ccagaccaga ttcaaacatc gcagggatca atgtgcatac tgcacggaaa
    29461 aatatgggac ggaatttagc gaaagaatcg ccagtaaaag cagatatggt cgttggcgta
    29521 cctaattctt ctttgtcagc cgcaagcggt tatgcggaag ctagtggaat cccttatgaa
    29581 atcggattag taaaaaatca atacattgcc cgaacattta tccagccaac gcctgagcta
    29641 agagagcaag gtgttcgaat gaaattatct gctgtacgag gagtagtgga aggtaaaaag
    29701 gtgattatgg tcgatgattc aattgttcgg ggtacgacaa gcagacggat cgtccatctt
    29761 ttgaaagaag caggggcaaa agaagtccat gtgaggattg cttctcctcc tttgaaatat
    29821 ccatgttttt acgggattga tattcaaacg cgtaaagaac tcattgcggc aaatcacacg
    29881 attgatgaaa tcaaagaatg tatcggtgca gattctttag gttttttaag tgaagagggt
    29941 ctgatcgaat cgatcggtct ggaaaaagat gctccgtatt caggattgtg tatggcttat
    30001 ttcaacggag attatccgac gccgttatat gactatgaag aaaaatatca ggaatcacta
    30061 aaagaaaaag tatcgttctt ttaaaagcag accaagaagg gagtatatga attcaatggc
    30121 aaatgcatac gcaaaagctg gcgtagatgt cgaagctgga tatgaagtag tagaacggat
    30181 caagaagcat gtcaaaaaaa cggaacgttt aggtatgatg ggcgctatag gaggattcgg
    30241 cggttgtttt gatttatcgg tctttcaatt aaaagagcca gtccttgtct cggggaccga
    30301 tggcgtgggg acgaaattag cagtggcaat cgaagcagac aaacacgata caatcgggat
    30361 cgactgcgta gcgatgtgtg tcaatgatat cttagcacaa ggcgcagagc cgttatattt
    30421 cttagactac ttagcaacgg ggaaaaatga tccgttacgt ttggaaaatg tagtaaaagg
    30481 tgtagcagat ggatgtgttc aaggaaatat ggcgctgatt ggcggagaaa cagctgaaat
    30541 gcctggtatg tactcaggta atgattatga tctagccgga tttgctgtag ggatagctga
    30601 aaaatctcaa ttattgacag gagaaacgat caacccagga gatgtgttgc ttggaatagc
    30661 atctagcggg attcattcaa atgggtactc tcttgttcgc aaaattttct ttgagcagca
    30721 gcagttttct ttatcatcaa aactgccaga attgaaaaaa acacttggcg aagaattgct
    30781 tgagccaacg aaaatctatg tttcttcctt gcttccgctg atcaaagaaa agaaaataaa
    30841 aggagctgca catatcactg gtggagggtt tgtagaaaat atcccgcgaa tgttaccaga
    30901 atctatggct gcacaaatca aacttggctc atggccgatt cttccaatat tcggctgttt
    30961 acaaaaatat ggtgaaattc ctgagatgga gatgtatgaa atcttcaata tgggcatcgg
    31021 tatggtcctg gcagtcgaag aatcgaaagt aaaagaaata gtacacgaaa ttgagcaagc
    31081 tggcgaaaaa gtttatgaaa tcgggaaagt gatcgccaaa gaaaaacatc gtgtggtgtt
    31141 tataggagaa gaacgatgag aatcgctgtt tttgcttctg gaaacggaag caactttcaa
    31201 gcgctagccg attatctatc gaaaaaagga ttggaatctt cgattgactg gttgttttgt
    31261 gatcagcctg aagcatatgt tttgaaacgt gcaactgcgt tgagtgtacc ggcagattgt
    31321 ttttcaccta aagaatttga ttcaaaaaaa gagtatgaag aagcaatttt gcataaattg
    31381 aaagaaaaaa agatcgattt gatcgtatta gctggatata tgcgaatcat tggaccggta
    31441 ttgctgaaaa attatgataa aagaatcatc aatatccatc cgtctctttt acctgccttc
    31501 cctggtttgc atggcatacg tgatgccttt gaagctggag taaaagaaac gggtgtcaca
    31561 attcattata tcgaccaagg tgtagatact ggaccaatca tccggcagga aaaagtgaga
    31621 attgaacagg aggacacgtt cgattcttta gaagaaaaaa tccatagagt agagcatcga
    31681 atctatccag aagtgattag tgaaattatt gaaaatggag gctatctgaa atgacaagag
    31741 cattgatcag tgtatcagat aaaactggga ttgtagcatt cgcccaaggt ttgattgaac
    31801 aaggagtaga aatcatttca acaggaggaa caaagcatgc gttggataaa gctgggatca
    31861 aaacgctttc gatcgaagaa gtgacagggt ttcctgaaat gatggatggc cgtgtcaaaa
    31921 cacttcatcc taaaatccat ggtggtcttt taggaagacg cgatctccct agccatatgg
    31981 aggcaatgga aacggaaaat atccaaccaa tcgactttgt ttgtgtcaat ttatatcctt
    32041 tcaaagaaac gattatgaaa ccagatgtcg aaatagcaga agctattgaa aacattgata
    32101 tcggtggtcc tagtatgctc cgtagtgcag caaaaaacca tgaatttgtc acctctgttg
    32161 ttgatccatc tgactatgaa gaagtacttt cagaattacg tcagtatggg catacttcac
    32221 tttctttcag acaaaaacta gcggcaaaag tctttcgtca tactgcggca tatgatgcac
    32281 tgatcgctca atacttaacg gattgggtgg aagaaaaaga accggaaaaa ttgacactta
    32341 cgtatgaacg aaaacaaacg cttcgttacg gtgaaaatag ccatcaagcc gctgcctttt
    32401 atcagtccgc tcttctggaa aaatattcga tcgcagcagc aaaacaactc catgggaaag
    32461 aactttctta taataatatc cgagatgcag atgctgcgct acggatcatg aaggaatatg
    32521 acgagccaac ggtagtcgcc ttgaaacaca tgaatccttg tggtattggg acagcatcta
    32581 cgattttaga agcgtgggaa gcagcgtatg aagcagatcc tgtttcaatc tttggtggga
    32641 tcatcgtttt gaatcgagaa gtagatctgc caacagcaga acagatgcat aagctgtttc
    32701 tagaaatcat cattgcccct tcttatacac aagaagcttt ggaattactg caaaaaaaga
    32761 aaaacatccg attactgaca gtagactttg cgcaggaaga aaatcaaaat cgagaagaaa
    32821 cggtctcagt cttaggtgga cttcttgtac aagatcaaga tctggcaata gaaaatgaag
    32881 aagagtggaa agtcgtgaca aaacgtaagc cgactccagc agaagcaaaa gcattagcgt
    32941 ttgcttggag agctgtcaaa catgtgaaat ctaatgcgat cgtactggca aacgaacgtc
    33001 agacagtagg aatcggagcc gggcagatga atcgagtcgg ttcagtaaaa attgcgattg
    33061 aacaagcgca agagaaaatg gaaggtgcag ttttagctag cgatgcttat tttccaatgg
    33121 atgattcggt tgaatatgca gccaaacatg gtataaaagc aatcattcag ccaggaggaa
    33181 gcatcaaaga ccaagattct attgatatgg cgaataaata cgatctagca atggtcttta
    33241 ctgatgttcg gcattttaga cattagagag gagtcggata aatgaacatt ttggtgatcg
    33301 gtgcaggtgg tcgtgaacat gcaataagta aaaaactttt agccagtccg aaggtggata
    33361 cggtgtattg tgcgccagga aatccgggga tgacaaaaga tggtatcaat tgtgtcgcta
    33421 tcagtgagcg agatcattca gcgttaatcc attttgttaa gaaagaggct attgattgga
    33481 gtatcgttgg tcctgaagtt cctttgttaa atgggatcgt cgatgatttt atggcggaag
    33541 gattgaaaat cttcggtccg acaaaagcag cagctctgat cgaaggttcg aaaagttttg
    33601 ctaaacaatt aatggatact tatcaaatcc cgacagctaa atccagaagt tttgaatgtt
    33661 acgaaaaagc agcagcgtat atcaaagaaa atggtgcgcc aatcgtagtg aaagcggacg
    33721 gcttagcagc tgggaaaggt gtagtcgtgg ctaccacagt gaaggaagcg ctggatgcgg
    33781 cagaacaaat gttgaaccag catcgatttg gggatagtag caaaaaaatc gtcgtagaag
    33841 agtttttggc aggagaagaa ttctcccttt tggcgtttgt ccgtaatacc aaggtgtatc
    33901 cgatggtcat ttcgcaagat cataagcggg catttgataa cgataaaggg ccaaatacag
    33961 gcggaatggg tgcttattca ccagtaccgc aaatttcaaa aaagatgatt gaaaaagctg
    34021 tggaagaagt tttaaaacca gcggctttgg gaatgaaaga actaggacgc tctttcacgg
    34081 gtgttttata tgcgggtttg attgctacga aggaaggacc aaaagtgatc gaattcaatg
    34141 cgcgtttcgg tgatcctgaa acgcaagtcg ttctttctcg gttgaagagt gactttgcgc
    34201 aagtaatcga tgatttatta gagaatcgta cagtagagtt aaagtggcag caagaaggat
    34261 acaatgtagg cgttgtggtt gcagctgccg gttaccccga agaatatgag acaggaatgg
    34321 ttctaccaga ttttctggaa gaagagcttt ctgtttacta tgctggagtt tcctcaaata
    34381 acggcaaact agttggagca ggaggacgtc tttatttagt agaagcatac ggtgagacga
    34441 tcaaagaagc acagaaaaaa atttacaccg cgttaatgga taaaacgaca gatggaacat
    34501 tttatcgtac agatattgga gaaaaagctg ccaatagcga actgatcgtg aagtaaatca
    34561 gctgcttcca tttataaaaa atacaacaaa cataatcgga agcgccgatt ttagtgaagc
    34621 cttttcataa agagtgtggt acacttttgt tgtgtatata aataaggagg agttcagatg
    34681 aaaaaaattc aattaggtac ttctgatcag aaagcagctg cagtgatctt aggctgtatg
    34741 cgtatcaaca atgcggaaga tccagtaaaa gtgattgaga cagcttatga aaacggcatt
    34801 gatttttttg accatgcaga tatttatgga aacggtgaat gtgaagaaat ctttgcagat
    34861 gctctagcaa aaacatcaat caaacgagaa gatcttttta ttcaaacaaa atgtggaatc
    34921 gttccaggtg tgatgtttga tttttctaaa aaacatatca ttgaatctgt agaaaaaagt
    34981 ttgacccgtc tgaaaatgga ttatgtggat gctttacttc ttcatcgtcc agatacattg
    35041 gtagaaccag aggaagtagc tgaagcgttt gatgaattgg aacggtcagg aaaagttcgt
    35101 tattttggcg tcagcaatca aaaaccaatg caaatcgaat tgctgaaaaa atatgttcgt
    35161 caaccattag tagctaatca gctgcaattt ggcttgaaac atactggaat gatcgatcaa
    35221 gggattcatg tcaatatgac agatgaagca agtatcgatc atgacggtag tgtacttgat
    35281 tattcccgat tgcatgatat gacgatccaa gcatggtcac cataccagta tggatttttt
    35341 gaaggtgtat ttatcgggaa cgaaaaattc cctgaattaa accaaacatt agaagaacta
    35401 gcagctaaat atcaaacgac accaactggc ttggcttctg cttggatttt acgccatcca
    35461 gccaatatgc aagtgatcgc cggtacgatg aacgtagggc gaatcaagga aatcgctcaa
    35521 gcttcagaaa ttaatatgtc tcgggaagat tggtacgaat tgtaccgtgc tgctggaaac
    35581 attttacctt aaagattgtc ataagcaggt caaaagggct ataaattaaa aagacagaat
    35641 aacttgaaag ctgttttcag cttcgagata ttctgtcttt ttttattgca aatggaaaga
    35701 gtatcattgt acggatttcg tttattagtt atttttgttt ttaaggaaaa gctgtgtccg
    35761 atattctttt ggagaaatcc cttgtttttt cttaaataaa taactgaaat agttagggtc
    35821 attataacca atttcaaaag caatatctga aatacgatag tctgattgct gcaataattt
    35881 ttttgctaat tcgattcttt gttctgtcag ataatcgatg aatgtttggt taaacgattg
    35941 agaaaaaatc gtactgaaat gagagggact taatgcaact tgttgagcga cccaagttaa
    36001 ggacatatct ggatcggtaa aattttcttt gataaaatcc aatgcatggt tcaaaattgg
    36061 ctgatatttg ttccttgaag gctgtgaggg cagagcagtt aagaaagaaa tgaacatata
    36121 aactgtcgaa cggtaaagcg agtcgtcggc gctgattgct aagcgttgac tggtggatgt
    36181 gcaatgaacc atttcttgcg ggattttctt ttctttcagg cagacatgct ggagtagctt
    36241 agtcaagaca aataaacgat ataatcgtgt tcgagttggt gtgccttgtg gtttcgtcaa
    36301 gtgttcgatg tacttagata cttcgttttt cgataatgaa gacaaatcaa gtgagaggtc
    36361 aaagtaaaag acagaatcaa ctggaagttt cgcttcttga atcaaatcct catagctgat
    36421 aatttgttct ttaagggaac tggcggtttc aagtatcatc tgcgtgatct caaaagatgc
    36481 aggtaattcg ctgattcttt ctgcgacagg accaatggcg acagaaaaat tatttttttg
    36541 tcccttttct aattcatgga ccaacgtttg ggctacctga taactggtct cgatcacatt
    36601 ttcttcaaga gaatcaacta ttaaaaattt gatgaatcga gaggaaacag cagagaagat
    36661 cacttgttga ttctccctaa ataaaaactt caaataatca ctgagatgag cgtaatcttc
    36721 aaagtctgta ctgacttggt ttgctgctaa taatacggtc atttttttcc ctgctaaaga
    36781 gcgattgaaa gattcagcaa gtttcaatgt ttcactgatc gtaagtgagc ctttgaacaa
    36841 accgttcaag aaatgatttt ttttcaattc gaaaacaaga tcagaagaag tgtgcgtttc
    36901 tttttgctgc aaatctaaag cagttactgc tttttctatt gcttgtttca attcgctact
    36961 tttaatcggt ttaagcagat aatcatctgc ctgtacctgg attgctcctt tcatataatc
    37021 gaaatcgtcg aatccactaa taaatatgag acgagtccaa ggaagtagtt tccttgcttc
    37081 ttttgaaaaa gtcaacccgt ccatgaaagg catttggata tcagtcagaa tgatgtcggg
    37141 ctgtaagtcg ataattgaag acagtgccat ctcaccatct ccagcttcgc cgacataagt
    37201 gattggataa taagaaccaa ggacagttat ttgttcccgc aagttattgc gaatgaggta
    37261 ttcgtcttcg atgataaaaa ctttatacat gtttgtttcc tccaattgtt ttgggagata
    37321 gagggatcat cagtgtgaca gttgttcctt ctcggtattt gctgtcaatc gtgataggtt
    37381 tttgatcatt tccgtaataa agaaggagac gcttgtttac gttgtaaagt ccgtagccga
    37441 tactgaaatc tgaatcgatc cctttggcta actctttacg tatttctgcc agtttttctg
    37501 cagggatgcc aatcccgttg tctataactt tgaattggat catctcatca attttgcatg
    37561 cggtaatacg aataaatcct ttgtgacgga cgtacttcgt tccatggtat acagcatttt
    37621 caatcaatgg ctgcaagatc atttttaaaa tagaaacagg aaaaagtgtt tctggtatat
    37681 cgatcttata gtcaagcata tggccgtatc ttatttttaa gatgactaga taatcattga
    37741 tatggctaat ttctttttca agaggaatcc agtcttgtcc tttgcttaaa gacgtacgaa
    37801 aaaagccgga aagtgcatgg gtcatagtca gagcttcttc aaagcagtct tgttcgatca
    37861 aagaaataat ggcatccaaa ctgttataaa taaaatgggg agtaatctga gcttgcaata
    37921 cacgaacttc actttgtgct aaatggtatt gtttcaaagc gttctcccgt aaagactggt
    37981 ttagatcttc cgccatttta ttcatgctag cggtaagtgt ttgtaattcc agtgtttccg
    38041 gcagggttaa acgaaagcca aggttccctg aagaaagttg ttctgacatc tcgatcagct
    38101 gattgatcgg ttcttggacc tttctctcta aaaagcgacg attctttttc gcatagaaaa
    38161 aaatggtact aagaactcca agttccacta ttgttaatag aatgagcgag cggacaagtg
    38221 tcgtattttt tttgcttgct aagtcgatct ccacacgaac aaaatcttgt aagatatctg
    38281 acagcagttg agtgacagaa tctacctgat tgatgatctc ttcattggta tccataaaat
    38341 cttttgccaa gatattattg atcagctcgt tttgataatc ttccagtgta tcgatcgtac
    38401 gtagcgatac atctaacgta ctaatttctt taagtgtatt tgtattattt ttgatctctc
    38461 gaatatcatt cctaagttct tctaggatat tttcctcatt gaactcatct acggttactt
    38521 ggccagaaat caagtcccac atactttcca aaactttttg atcaaccttc aaagcaattg
    38581 catctgcttt ttggatattt gcgatcgtct gttgataaat caaaagctgt tgcgaatata
    38641 acagtatgct cagtagcaaa gggataacag caaatagaag catggctttg tttgcttggg
    38701 caaaaatctg ttttatgctt aaattttttg tcatgatact tctccagtca ataatttctg
    38761 gttgggatgt tagctatatt ctgctgggaa aagacagtct cggaaataaa aatatcttta
    38821 ggtaatgttt ttcctgtttg aatatttcca aaataacgag taacggtatt ggctacatac
    38881 cagccgacat caggtttaca ctcgactaca caattgacga ttcctgagcg tagcttctcg
    38941 atcatatctt cttgtccatc aatagttaca atgatcaaat cttctccagg tttgattgat
    39001 gtttctttta tcgcagctaa agcaccgtga gtcatttcat cactatggct gtataataca
    39061 tcgatttcgg ataaatcatt tgtttctaaa tatcgtttca tctggtcttt tcctttcatc
    39121 cgaataaaat caccgacaat tcggtgaaca atagtcatcg gaggtttatg gtcgatggtt
    39181 ccatcttttt ttagggttgg tttacgattg attgattcca aaaatccttc ggagcgtagc
    39241 ttggtcggtg tggagttctc tgaaccagca agttctagga ttctgatttc ctgtttcttt
    39301 gaatttgtga agtgattgct gacaaataaa cccgcccgat ttccttctgc tttgaaactg
    39361 gggccaatgt gggtgacgaa aagctcggga tcattcgttt gaatatgtct gtcgacaagt
    39421 atgacaggga tccctgctcg ctttgcttct tttaatacag agtcccaccc ggattcttgc
    39481 aaaggagtaa aaatgatcat atccacttta taggcaatga acgtccgtat atcttggatt
    39541 tgccgttcct gattcatgta gccatttcgg tagagaactt ggtaatcttc tttttcaagc
    39601 gcagtgataa ttgattcagt atgctttttc cgccagctac tctccgttcc tgattgcgaa
    39661 aaaccaacga ctagtgggtc aggtgcttcc tttgtattag gtgtacaccc catcatttgg
    39721 taagcgatta caacaagggc taaaaaaaat aaaacacgtt tcactttaaa tcactccatc
    39781 tggatttgtt agtactatct tatcagataa aagggaaaat caaagtcaaa aggaatcaat
    39841 cgaaaaaaat ccaagaaact taaaaaaatc caagacaaaa aaagtacacc taaaaaattt
    39901 aaagtaaatc ccataaaaaa atcaatgtta acgctttctt tattagctat actcggtgta
    39961 tcaattgaaa tgggggataa aaaatgaaaa acaaatttag aaagattgtt gggactatcg
    40021 ctattttgac cgcaagcatt ctattaagtg cgtgtggcaa ttcaggatct gcagatgata
    40081 gtacggggta tgtaggaatc gctatgccga ccaaatcagc agaaagatgg atcgctgatg
    40141 ggaacaacat ggtctcggaa ttagaaaaac tgggttataa aacagatctt caatatggag
    40201 aagataaagt agaaaatcaa gtagcacaaa tagaaaatat gattacaaaa ggggtagata
    40261 cacttgtgat tgcttctatc gatggttcgg ctttaactga tgtgttagct aaagcaaaag
    40321 aagcagatat caaggtgatc gcctatgatc gtttactgat gaattcagaa aatgtcgatt
    40381 attacgcgac ttttgataat tttggagtag gtgtatcgca agcagcttat attgaagagc
    40441 acttaggatt gaaagaagga aaaggaccat tcacgattga attatttggt ggctcgcctg
    40501 acgacaacaa cgcactaatc aattacaacg gagtgatgtc tgttttacaa ccatatatgg
    40561 acaacggtca gttggtcgtg ccatctggac agacgagttt cagtcaaatc gctacgcttc
    40621 gctgggatgg ttctacggcg caagcaagga tggataatct gttaagcgca aattatactg
    40681 accaaacatt ggatgctgtt ttgtcgccat atgatccaat aagtttagga atcatttcgt
    40741 cattaaaagg cgtggggtat gggagtgaaa gtaaaccttt acctgtgatt actggacaag
    40801 atgcgacagt tgctggcgtt aaatcgatca ttgccgggga acaaacacaa acgatcttta
    40861 aagacacacg tatcttagca aaaaatacga ttgaaatgat caaagcaatc agtgatggag
    40921 aagaggttcc ggtcaatgat actgaaactt atgataatgg ggtgaaaact gtccctacgt
    40981 atttagcaaa tacagtatct gtcgataaag ataattatca agcagagctg atcgacaccg
    41041 attattataa agaatccgat ctgaaaaatt aagaggaacc aaacaaggaa ctaaagagat
    41101 ctaagtcaga gagaggataa gaattatggc ggattgtatt ttaaaaatgg cagatatcac
    41161 caaaaaattt tctggaatcc gagcgttaga ttgcgtgaat ctgatgattg aacgtgggga
    41221 aatccatgca ttgtgcggag aaaacggagc gggaaaatca acattgatga atgtcttgag
    41281 cggcttgtat ccatatggct cctatgacgg ggaaatcttt tatgatggaa agctgtgtca
    41341 atttaaagat ttgaaagata gtgaagaaaa aggcatcgtc atcattcatc aagaattagc
    41401 actaagtcct tatctttcaa taaaagagaa tatttttctc ggaaatgaac aagcagaaag
    41461 aggcgtgatt gattgggaac tgacagaaaa gaaaacatat gaactgctga ataaagtcgg
    41521 tttgtctatc gacccgaatc ttctagtatc ccagattggc gtagggcaac agcaactagt
    41581 tgaaatagct aaagcattat caaaatccgt ccgtctgttg attttggatg agcctaccgc
    41641 tgcattgaat gaagaagaaa gcgcgaattt gctgagattg atccgagagt tgaaagagca
    41701 aggtgtaacc tccatcatta tttcacataa gctgaatgaa atcgtggata tcgcagatcg
    41761 aatcaccatt ttacgggatg gacagacgat tgagacacta gaaaatgaaa tgatcagcga
    41821 agagcatatt attcgcggga tggtgggcag agatttagtt gatcgttatc ctgaaagaaa
    41881 accggatatt ggagaagttt attttaaagt agaagactgg acggtctatc accctcttga
    41941 tcacgagcga atcataaacg accacatcaa cttgcatttg aaaaaaggag agattgtagg
    42001 aatagctgga ctgatgggag cgggcagaac tgaattcgct atgagtctat ttggacattc
    42061 ttatggaagc aagatatccg gacgtatatt aaaggaaggg gcagagatat cagttaagac
    42121 cgttccttca gccattgcaa acggactcgc ttatgtctcg gaggaccgaa aatctttagg
    42181 actgaatctg ctgatggata ttcgggaaaa cgtgacgctg agcagtttgg ataaaataag
    42241 tcaaaaagga gtattagata aagaaaaaga agtaactgag gcagaaaatt tccggaaaaa
    42301 gatgcgtata aaaacaaact ccatccatca aattgtcagt agtcttagtg gtgggaatca
    42361 acaaaaagtc gttttatcca agtggctgat gacacaaccc gatattcttt ttttggatga
    42421 gccaacccgt gggatagatg ttggggcaaa atatgagatc tacacgatta tcgaagaaat
    42481 ggcagcaaat ggcaaagctg tctgtcttat ctcttctgaa cttcctgaaa tattagggat
    42541 gtgtgatcga atctatacga tgaacgaagg acgtattaca ggagaagtct cgcgagaaga
    42601 tgcagatcag gaagtcttga tgaaattaat gacgaaagaa gaggtgggtt aagttggaac
    42661 aggcaaaaaa tcttacggat aaaaaagaga aaaaactaaa tttgaaaagt agagcagctg
    42721 atctttttgg tcgctacagc atggtgatca ttttagcggg actacttatt gcgtttcaat
    42781 tgatgacgga tggtattttc tggcgtccat tgaatataac taaccttgtt ctgcaaaata
    42841 gccatatatt agtactagct gcagggatgt tattagttgt gctcttaggt catgtggatt
    42901 tgtcggtagg gtcagtgatg gcgtttgttg gtgcaattgc gggcatgatg atggtcaatc
    42961 gccaaatgaa cccgtggatg acagttatcg catgtcttgc agtaggcggg ctgatcggcg
    43021 catggcaagg tttttgggta gcttatgcag ggataccggc gtttatcgtg actttagcag
    43081 gattgctgat gtttcgtgga ctgacacaag ttgttctagg aggccaatct ctagcacctt
    43141 ttccagctgt tttccaaaaa atgtctacgg gttatttacc agacttaagc gaaggaagca
    43201 gccttcactt cttgacattg attttaggaa tgatcatcac gatcgtgtta gttgttggtc
    43261 aatggcgaac aagaaatcgt cggaaaaatc atttatttga agtggaatct ccaacagctt
    43321 tcttggtaaa ggcggtattt acagcagtcg ttgtactagg aataacttat atctttgcct
    43381 cttatcaagg gtatccgatt attttgatca ttcttggttt gatcgttgca gcatatgggt
    43441 ttttgacaaa taaaacagta gcaggtcgac agatttatgc gacgggcgga aatcgaaaag
    43501 cggctgaact atcagggatc aaaacaaagc gaatcacgtt ctgggtattc gtcaacatgg
    43561 gagtcatggc agctttagct ggattagttt tagctgctcg attgaatgcg gcaacacctc
    43621 aagcaggtac atcgatggaa ctggatgcaa tggcggcagt atattttggt ggtgcttcga
    43681 cttccggcgg cattggaaca atcatgggtg cgattgtcgg tggcttggtc atgggtgtat
    43741 tgaacaatgg catgtcgatt ttaggcgtcg gggtagactg gcagcaggca atcaaaggat
    43801 tgatcttgct tttagccgtt gtgctagact tgtataataa gaaaaaacga acaacgtagg
    43861 agaacgccgg ttattcagaa aaaagactgt gacaagacat ttgtcacagt ctttttttcg
    43921 ctaaaagcga acattcattg tttcgtttgt atagactaaa aataatatat gtttttttac
    43981 cattcgtata aattctcttt ttgctcttga tttttttgct taattgagtt aaattacata
    44041 gggcgctaaa aaaagccttg attaaattaa taatgttcgt gttttgctgg atgtgaacat
    44101 caggaggata atgtaatgaa agtatttgat tacgaagata ttcaattaat tcctaataaa
    44161 tgtatcgtaa atagccgttc tgaatgtgat acaacggtca cattaggtaa acatacattc
    44221 aaaatgccag tagtgcctgc caacatgcag acgattattg atgaaacaat cgcagaattc
    44281 ttagcggaaa atggttattt ctatatcatg catcggtttg atgaagcagc tcgaattccg
    44341 tttatcaaaa aaatgaaaaa gcgtggattg attacctcga tcagtgttgg cgtcaagaaa
    44401 gaggaatatt cctttataga gaagttggca gaagaatcgc taaatcctga ttatatcact
    44461 atcgacatcg cgcatggaca tgctaactca gttattgata tgattcagca tattaaaaaa
    44521 tatttgcctg aaacttttgt gattgccggt aatgttggta caccggaagc cgtccgtgaa
    44581 ttggaaaatg cgggcgcaga tgcaacaaaa gtcgggattg gtccaggaaa agtatgtatt
    44641 acaaaaatca agacaggctt tgggactgga ggctggcaac tggcagctct tagatggtgt
    44701 gcgaaagcag ctcgcaagcc gatcatcgct gacggtggga tcagaacaca tggcgatatt
    44761 gcaaaatctg tccgttttgg tgcgacaatg gtcatgattg gttcattgtt tgccggtcac
    44821 gaggaatctc ctggcgaaac aaaagtcgaa aatggaatcg tgtataaaga atactttggt
    44881 tctgcttcag aattccaaaa aggcgaaaaa cgaaatgttg aaggaaagaa aatctggatc
    44941 caacacaaag gatctttgaa agatacacta gtggaaatgc aacaagacct tcaatcatct
    45001 atttcttatg ctggaggaag agatctggaa gccattcgaa aagttgacta tgtcatcgtg
    45061 aaaaattcga tttttaatgg agacacaatc taaaaaataa ataaaatatt aggatgttgt
    45121 gaaaaagttg tcctgcatta agtaataaga acagccaaac aaaaatagtt ctttatatgt
    45181 tttgtttggc tggaattatt atcgcagata caagcttttg aacatcatta ttcagaataa
    45241 gggactgtga taagattttt gtcacagtcc cttatgtttt gcaaaaaaag tttttctttt
    45301 ttctcgtaaa ttcggtaaaa tcaaaagaaa aaatagacaa tagaaaagag aagcttatgt
    45361 gggaaaaagt agagaaaaaa caaggaccga tttatcgtca aattatggaa cagattatga
    45421 gagaaatcga aaacggaagg atcaatcctg gaagtcaact tgaatcagaa cgaaaactag
    45481 ggcaactttt tggtgtgaat cgttccaccg ttgtccatgc attggaagag cttagggagc
    45541 ttggggtact aacgagcaaa cgtggcagcg gatggtttgt taatcagact gaatggggga
    45601 aattcgctgt tccaagaatc gattggcggc aaatgatctc tcctcgttat gagcagacgg
    45661 actggtatga gcaaaaaata agagaagcaa agcagatcca aaaaacatcg tttcttgatt
    45721 tatacgctag cgagatgcca gatgagcttt tgccgaattt tgagtttcct tcttattctc
    45781 ttgaagaaat cttagcggaa gaaaaagaaa tggatctttt aggctatact ccgttacgta
    45841 acaaaatcaa acggtatttg gaaagtaaat ttgaattggc attttccccc aaccagcttc
    45901 ttgtgactgg tggcggtcag caagcaatct ttttgatttt acaaacgatt ctttcagctg
    45961 gagaggggat agctgtagag tcaccttctt ttttttaccg attacctctt ttcaaagctt
    46021 caggaacgcg tttatttggg ataccgatgg atgaagaagg gatcgactta gaaaaactga
    46081 aagaatcgat ccataaaaat aaattgaaag cagtgcttat caacccgaat tttcaaaacc
    46141 ctacaggaaa agtgatgagt caaaaacgac gagaaaagct agtagaattg tgtcgacagt
    46201 atcggcttcc aattattgaa gacgatgtat ttacggatct ttcatttcta aaccaagaag
    46261 aagtccttcc tatacgaacg attgatccgg ataatgtgtt atacgtcggt tcgttatcta
    46321 gggttttagg aaaaacaacg aaaatcggtt gggtgatagg acctgagact tttatctcgc
    46381 aactagctca agcgcaagaa atgatggagt tttcgatgaa tatccttaca caaatcacag
    46441 tggctaatgt atttaatgaa gcaattgatt tgaaaatgca agatgtaaga aaaaagttga
    46501 aagaaaaaag ccgactgata agcgcttggg gagattcaca atcgtttttc aagcttcatt
    46561 caattttagg tggttactat gcctggatta cttgggatgg gaaaaaacta gaccccgaac
    46621 tagcagaaaa agtagtagat atgggtcttg gaattgcacc aagtctactt tttgggcaag
    46681 atataaatgg aatcagaatc aattacagta ggctggatga aaaccaaata ccgttgtttt
    46741 attcaaagat gaaaattcta gaaaagtggt taacagaata atttcacaaa gtaaatagat
    46801 taaagaatat aacagcttgg atttaaattt caagctgttt cttttttttc ggaaaaagaa
    46861 tacgatataa agaaactaag aaaaaaccat tatttgtacg tccgttcacg atgtgtaaat
    46921 aaaataaatg tttgcaacaa aactgtataa caccaacgtt tttaaataga aacagatggt
    46981 tgtaagtttg attagaaaat agaaaaaatg cagatgaaaa ataaaacgct ttccttattg
    47041 tgattttatt cactaatgct gttaatatgc ggattggcat aatttccttt catcgtgaaa
    47101 atttgtgctt ttagcttgta tttctcataa atccatgata atttattaat gaagacggtt
    47161 aaatagtgat acagttttat tcactgtttc aatcgcagaa tgaagagatt ttcttataga
    47221 tgagagagga atgtgtgaca aatggcaaac aaaaaagcac cgatcgactt ccaagcactg
    47281 ctagatgaag tcaatgcaga tttcccagta tatcaagcac ttgatcaaga tggaaacgta
    47341 gttaacaaag atttagtacc tgatttatcc gatgatgaac tcgttgaatt aatgactcat
    47401 atggtatggt ctcgtgtatt agaccaacgt tcaacagcgc tgaaccgcca aggacgccta
    47461 ggcttttttg caccaactgc tggacaagag gcaagtcagc tggctagtgc ttacgcattt
    47521 gataaagaag atgttcttct tccaggttat cgggatgtac ctcaactagt aaaacatggt
    47581 ttacctttat ctcaagcttt tttatggtct cgaggacatg ctgcaggtaa ttcttatccg
    47641 gaagaattga aagctctacc accacaaatt atcatcggtg cacaatatgt acaagcagcc
    47701 ggtgttgcat taggtttgaa gaaacgaaac aagaaaaatg tcgtcttcac ttatactggt
    47761 gatggcggtt catcacaagg tgatttttac gaagcaatca atttcgctgg cgcttaccat
    47821 gcaaatgccg tattttatat ccaaaacaac gggtatgcga tctctacacc tcgtgaaaaa
    47881 caaactgcag caaaaacact tgcacaaaaa gctgtcgcag ctgggattcc tggtattcaa
    47941 gtcgatggaa tggatccgct tgcagtatat actgtatcta aaatggcacg ggaatgggcg
    48001 atcagtggaa atggaccagt cctaatcgaa acactgactt atcgttatgg accacataca
    48061 ctatctggtg acgatccaac ccgctaccgt acaaaagaca cagatgacga ttggcagaaa
    48121 aaagatccat tgatccgctt ccgtaaatat ttgacggaaa aaggactttg gtctgaagaa
    48181 aaagaagaac aagtcatcga agcaactaaa gaagaaatca aagcagctat tgctgaagcc
    48241 gacaaagtac caaaacaaaa ggtttcagat ttcttgaaaa acatgttcga agtatctcca
    48301 caatcaatca aagaacaaat tgcaatttat gaagcgaagg agtcgaaata atcatggcac
    48361 aaaaaacaat gatccaagca atcacagatg ccttagcact tgaactagaa aatgacgaga
    48421 atgtcgttgt ttttggtgaa gatgttggga aaaacggagg agttttccgg gcaactgaag
    48481 gattgcagga aaagttcgga gaagaccgag tattcgatac tcctttagct gaatctggaa
    48541 tcgcaggatt gagtttcggt cttgcgttag aaggatttcg tccagttcct gaaatccaat
    48601 tctttggttt tattttcgaa gcaatggacg aagtagtagc tcaaatggct cgtacaagat
    48661 atcgaatgag cggcactaga aatctaccca tcacaattcg ttcgccattt ggtggcggtg
    48721 ttcatacacc agaattgcat tcggataatt tagaaggttt gatcgctcag tctcctggta
    48781 ttcgagtagt gattccttcc aacccttatg atgcaaaagg actattgatt tcttctatta
    48841 gaagtaacga tccggttgtt ttcctagaac acatgaaact atatcgctca ttccgagaag
    48901 aagtgccgga tgaagcttac gaagttcctt tggataaagc agcagttact cgtgagggaa
    48961 cagatgtatc tattatcaca tacggagcaa tggtgcgtga agcaatcaaa gcagcagaca
    49021 atcttgcaaa agaaaatata tctgttgaaa tcattgatct tcgtacagtt gcgccattag
    49081 atgtagaaac gatcattcaa tccgtggaaa aaactggtcg cgtagttgtt gtccaagaag
    49141 cacaacgaca agcgggcgtt gccgcgcaag tagtttctga gatctcagaa cgcgctatcc
    49201 tttcattaga agccccaatc ggacgagttt ctgcacctga tacagtcttc ccatttggac
    49261 aagcagaaaa tgtctggttg ccaaatgcaa aagatatcga agacaaagta aaagaaatcg
    49321 cggaatttta agaaaagaag ggacgaaaca aagtcatggc ttatcaattt aaattgccgg
    49381 atatcggtga aggaatcgca gaaggtgaaa tcgtcaaatg gttcgtcaaa ccaggagata
    49441 cgatcaatga agatgataca ttactagaag ttcaaaatga caaatcagta gaagaaatcc
    49501 cgtcacctgt tacaggaacg gttaaaaatg tgattgttcc agaaggtacc gtagcaaatg
    49561 ttggggatgt attagtagaa atcgatgcac caggacacga agacaatgaa ggggacagtg
    49621 gtgtagccgc agaatcccaa actccagcta aaccggctgc tgaacccact gttgatacag
    49681 aatcagctgg atcgtcaagc gaaggagtct tccaatttaa gttaccggat atcggtgaag
    49741 gaatcgcaga aggtgaaatc gtcaaatggt tcgtcaaacc aggagatacg atcaatgaag
    49801 atgatacatt actagaagtt caaaatgaca aatcagtaga agaaattccg tcacctgtca
    49861 cagggacagt taaaaacgtg attgttccag aaggcactgt agcaaatgtt ggggatgtat
    49921 tagtagaaat cgatgctcct ggacacaata gtgcaccgtc aactagtgcg ccatcagctg
    49981 aagcaccaaa agaaaaagtg gaaacatcag gttcagcaag tgtcgttgaa gctgccgatc
    50041 caaataaacg tgtattggct atgccatctg ttcgtcaatt tgcccgtgaa aaagatgtag
    50101 atatctcaca agtaactgca actggaaaag gtggcagagt aacaaaagag gacatcgaaa
    50161 acttcttggc aggtggtcca agcagtgcac cagcgaaatc agaagcgcca gaagcggcag
    50221 caccgaaaga agcagctcct gcagcagaaa gcaaaccagc tgcaccagca aaaccattca
    50281 agtccaactt aggagacttg gaagaacgtg tagcaatgac gccaacacgt aaagctatcg
    50341 ctaaagcaat ggtcaacagt aagcatacag ctccacacgt gacattgcat gatgaagtag
    50401 aagtgtctaa actatgggat aatcggaaac gatttaaaga agttgctgct gcaaatggta
    50461 cgaaacttac tttcttgcca tatgtcgtga aagctttaac agcgactgtt aagaaatacc
    50521 cagtattgaa tgcatctatc gacgatgcaa accaagaaat cgtttataaa cattactaca
    50581 atatcggtat tgcaactgat acggatcacg gactatatgt accaaatgtg aaagatgcag
    50641 accgcaaagg aatgtttgct attgcagacg aaatcaatga gaaagcaaaa ttagctcatg
    50701 acggcaaact atctgcagaa gatatgcgca atggaacaat tacgatcagc aatatcggat
    50761 ctgtaggtgg cggttggttt acaccagtca tcaactatcc agaagtagct attttaggtg
    50821 taggaacgat tgcacaacaa ccaatcgtaa atgctgaagg cgaaatcgtt gtcggtcgtg
    50881 tgatgaaact gtcattaagt ttcgatcacc gtatcgtaga tggagcaact gcgcaacaag
    50941 caatgaataa tatcaaacgt cttttagctg atccagagct attaatgatg gaaggatgat
    51001 aaacaaatgg tagttggaga ttttgctgta gaattagata cagttgtaat tggtgcggga
    51061 cctggtggct atgtagctgc catccgcgct gctgaaatgg gacaaaaagt agcaatcatt
    51121 gaaagagagt atattggcgg tgtttgtttg aatgtcggct gtattccttc aaaagcactg
    51181 atagctgcag gacaccatta tcaagagtca ctagattctg aaatgtttgg agtaactagt
    51241 gaaaacgtca aactagattt tgcaaaaaca caagaatgga aagaaaacaa agttgtccat
    51301 acgttgactt ctggtgttgg tttcctatta aaaaaacata aggttgaaac aatcgaagga
    51361 gaagcgttct tcgtagatga tcacacacta cgcgtcattc atccagattc agctcaaact
    51421 tattcgttca ataacgcaat catcgcaaca ggttcccgtc caatcgagat tccaggattt
    51481 aaattcggag gacgtgtgtt agattctact ggcggattag cattgaaaga agtacctaag
    51541 aaatttgtga tcatcggtgg cggtgtgatt ggtgccgaat tgggcggagc gtacgcaaac
    51601 ttaggagcag aagtaacgat tcttgaaggc tcaccacaaa ttttaccaac ttacgaaaaa
    51661 gatctagtaa aattagtaga agatgatttc aagaaaaaag gcgtaacagt cgtaacgaat
    51721 gcaatggcga aagaagcagt cgataacggt gacagcgtga cagtgaaata tgcagtggac
    51781 gggaaagaag aatccgttac tgctgattat gtgatggtca ctgtaggtcg tcgtccgaat
    51841 acagatgata tgggcttaga acaagcgggt gtcgaagtag gagaacgagg attgatcacg
    51901 gtggataaac aaggacgtac gaacgtacct aacatctatg ccatcggtga tatcgttcca
    51961 ggggcggcat tagcacacaa agccagttat gaagcaaaaa tcgctgctga agcaatctct
    52021 ggcaaaaaag tagctgtaga ttataaagca atgccggcag tagccttcac tgatcctgaa
    52081 ttggcttctg taggtatgac gatcaaagaa gcaaaagatg ctggtatcga agcaaaagca
    52141 tataaattcc cattttcagg gaacggtcgg gcattatcgc ttggtaaaac agaaggattc
    52201 atccgtctag ttacgacgat cgaagataac gtgcttattg gcgcgcaaat cggtggagtc
    52261 ggcgcaagtg atatggtctc tgaattagct ttagcaatcg aatcaggaat gaatgctgaa
    52321 gatatcgcct tgacgattca tcctcatcca tctcttggcg aaatcgtcat ggatgcttcg
    52381 gaattagcat taggtttacc aatccatatt tgatttgaat aatacaggcg aaacgcaact
    52441 gaaaaatcag ttgcgttttg ttttttagaa ttatcaataa tattattatg taaacttaaa
    52501 aatatgacaa cttcttggtt tattaccact tcctatgcta cactgaagag gaatatgaaa
    52561 taggagagtt gaagatgcaa gaatatcagt atccacttga tttagattgg acaacagacg
    52621 aaatggtcat tgtaatgaag atgtgggaag atctggaacg tgcgaatgaa aaagggataa
    52681 acaatgaagc ttttttgaag acttatcagc agtttaaaac tgttgtcaaa tccattggtg
    52741 aggaaaaacg attgggacgg gaatttgaaa aagcttccgg ttattcttta tatcgtacag
    52801 tgcagcaagc aaaaaaaaat ccaaacaaaa ctttgagaat gaacgggtga gataaatgga
    52861 acagatgatt gatcatatca agtcctggct tgaagaagct ggtgagaaaa tcaaatcttc
    52921 tcaacaaaca ttaacaatct cgcaaaaatc aaatcgaacg gatctagtaa caaatgtcga
    52981 tcgaaacatc cagaattttc taatcgaaaa aatccattcc tttgatccag aggcgaaaat
    53041 attggcagaa gaagaagggt gtaatcaatt atcggatctc gatggaagag tctttatcat
    53101 cgatcctatt gatggcacct tgaattttgt gattgaaggg gaaaattttt gtattatgct
    53161 cgctgtttat gaatccggcg ttggaaagct tggtttcatt tatgacgtga tgagaaatga
    53221 acttttttgg ggtggaaaag gaataggcgt gtataaaaat gatgagccat tgcctagacc
    53281 agcaaataaa tccttatcgg aaggcttact tggtgtgaat agttatcttt tcggtcataa
    53341 taaatatgga atccgagaaa ttgcggaaag cagcatgggg acacgtatgt acggatgcgc
    53401 tggtcttgaa ctagtggcaa tcttgaaagg aaaccacatt gcttatattt caaaccttag
    53461 cccttgggat tatgcagcgg gaaatgtctt attggaagag tttggtatgg taacaagcgg
    53521 tctttttggt actcctttga catttgaaaa aagggaatac tatttagcag ggacttcttg
    53581 tgcatatgca gaaatcgcag accttttgaa aaaagaaggc tgaaaaaaag gtagaaatca
    53641 ttcacaaaaa tgataaaaac gagcaaaaga ttaattttct cgaaaaaatg aaaacatttt
    53701 actatatttc atgaaaaaag tctgctataa ttagcagtcg agtaaaattt gccctgtcat
    53761 aaagaaccaa taaaaaagga gttagttaca ttgaattata gaaacgatat ccgtaacgtc
    53821 gcaattattg cccacgttga ccacggaaaa acaacattag ttgatgaact attaaaacaa
    53881 tcagatacat tagacgcaca tacgcaattg caagaacgtg cgatggactc aaatgcgcta
    53941 gaaaaagaac gtggtatcac gattttagcc aaaaacacag ctgtagacta taaaggtatt
    54001 cgcgtaaaca tcatggatac tccaggacac gcggacttcg gtggcgaagt agaacggatc
    54061 atgaaaatgg ttgacggcgt tgtgttggtc gtagatgcgt atgaaggaac aatgcctcaa
    54121 acacgttttg tattgaaaaa agcactggaa caacatatca caccaatcgt tgtcgtaaac
    54181 aagattgaca aaccttctgc tcgtcctgag catgtcgtag atgaagttct tgaactattc
    54241 atcgaattag gagcagatga tgatcagtta gactttcctg tgatttatgc atctgcacta
    54301 aatggtacgt caagcttgtc agatgatcca gcagatcaag aaccaaccat ggcacctatt
    54361 tttgatacaa ttattgaaaa aatccctgct cctgtcgata acagcgacga accattacaa
    54421 ttccaagttt cattacttga ctacaacgat tatgtaggtc gtatcggaat cggacgtgta
    54481 tttagaggaa caatcaaagt aggagaccaa gtagcattaa ttaaattaga cggaacagtt
    54541 aagaaattcc gtgtaacgaa attatttggt ttctttggac taaaacgtct agagattcaa
    54601 gaagcaaaag ctggagactt gattgctgtc tcaggtatgg aagatatctt tgtcggtgaa
    54661 acagttactc ctgtggatca tcaagatgcg ttacctatcc ttcacattga cgaaccaaca
    54721 ttgcaaatga ctttcttagt taataattca ccatttgccg gtcgagaagg taaattcgta
    54781 accgctcgta agattgaaga acgtttgatg gcagaacttc aaacagatgt atccttacga
    54841 gttgaaccaa caaactctcc agatgcatgg acagtttctg gtcgtggaga attgcatttg
    54901 tctatcttga ttgaaaacat gcgccgtgag ggatacgaat tgcaagtatc tcgtccagaa
    54961 gttattgaaa aagaaatcga cggtgtaaaa tgcgaaccgt ttgaacgcgt gcaaatcgat
    55021 acaccagaag aatatatggg tagtgttatc gagtccttga gcttacgtaa aggtgaaatg
    55081 caagatatgg tccatacagg aaacggacaa atccgtttga cattcttaac acctgcccgc
    55141 ggtttgattg gttattcaac tgaattcctt tcaatgacac gtggttacgg aatcatgaac
    55201 catacttttg accaatatct gccaatgctt cctggtcaaa ttggcggacg tcaccaaggg
    55261 gcgcttgttt cgatcgatac aggaaaagca acgacttatt ctatcatgag tatcgaagaa
    55321 cgcggtacag tcttcgtaga accaggtaca gaagtatatg aaggaatgat tatcggggaa
    55381 aacagccgtg ataatgattt gactgtcaac atcacgaaag caaaacaaat gacaaacgta
    55441 cggtctgcta ctaaagacca aacatctgtc atcaaaaaac caaaacaatt gacgttggaa
    55501 gaatctttgg aattcttgaa tgatgatgaa tattgcgaag taacaccaga aagcattcgc
    55561 ttgagaaaac aaattttaga gaaaaatgct cgtgaaaaag catctaaaaa gaaaaaataa
    55621 tctgtaaaag gatgaagaga gaaaccagct tgttataaaa aatagctggt ttcttttttt
    55681 gtccaactct tttctgtgga gaagtcatct ttgtcaatgg acataaattc agaaaatacg
    55741 ccgaaagacg tttaaaagac ttttaaaaaa cttatttcta gagagttttt gtttcataat
    55801 aagataatgt ttcacgaaag gagatcaact tgtccttcga agaaaatcga agtaaaatgg
    55861 caagagaaag gagcgggaag atgaacgact tattaaaaca atactttggt tatgatgagt
    55921 ttagacctgg tcaaaaagaa attatccaga aagtcattga tcaggaaaat gtattaggaa
    55981 tcatgcctac cggaagtggg aaatcaatct gttaccagct tccagcttta ctattagatg
    56041 ggcttactgt ggttgtgtcc cctttaatct ctttgatgaa ggatcaggtg gacgcggcga
    56101 atcaattagg tatacccgcc acttttatca atagctcgtt agatggttac gaaacagcta
    56161 gacgcttcca agaaatcgat agacagcagt accgtttact ttatatcgct cctgaacgtt
    56221 ttatcatgcc ggattttatc caagcaatga agcgatggaa cgtccgtatg atcgctattg
    56281 acgaggcaca ttgtatctct cagtgggggc atgatttccg cccaagttat ttacagatgg
    56341 cgaaccagct agatcaactg ccaaatcgtc ctgtaattgt tgctttgaca gctacagcga
    56401 ctgtgcaagt agctgctgac ataaaaagac ttttaaaaat tccagaaaac aaccatattc
    56461 agactggttt tgaacgagaa aatctacgat ttcaagtaat taaagatcaa aaaaaagaac
    56521 aatatctaat cgaatattta aagatcaaca aaaatcaatc tggtatcatt tatgcagcaa
    56581 cgagaaaaga agtagaccgt ctctatcatt tgcttaaaaa attcgatttt tccgtgggta
    56641 gatatcatgg tggtctaaat gagaatgagc gaacagaaat gcaagaagcc tttttatacg
    56701 atcgcttgca gctgattgta gcgacaaatg catttggtat gggtataaat aaaagcaatg
    56761 tccgttttgt tatccattat caaattcctg gctctctaga agcatactat caggaagctg
    56821 gtcgggcggg aagagatggt ctttccagtg aagccatcct gcttttctct cctcaagata
    56881 tccaagtcca aaagtttttt atccagcagt cccaaagaga agaagggcaa aagcaaaaag
    56941 aatatgaaaa attaaaagcg atgacagaat acgtgtatat tgagtcctgt cttcagcaat
    57001 acatcctaaa ctattttggc gagacaagca gtccgtgcaa ccgttgtggt aactgtttag
    57061 atgacagaga aatagtagaa gtaacgacag aagcacagat ggttctttct tgcttaaaac
    57121 gtatgggtga gaactatggt aaacaaatgc tgatgaaagt cttagcagga tcgaaagaac
    57181 aaaagctgca agctttaggt tttggacatt tatctaccta tggactgatg aaaaaccaat
    57241 cgcaaaaaga aacgatgcag ttaattgaat atttgatatc gaatggctat cttctgacca
    57301 tcaatggtga gtatcctgtt ttgaaagtaa cagaaagagg gatacaagta ttgaaaggac
    57361 aagaatctgt ttatcgaaag gaacccaaga aagtccagca gctatcggat gaagaaaccg
    57421 atacactatt tgaagtgctg cgggaactgc gaacggatct agcatcagaa gcaggcgttc
    57481 ccccgtatgt cgtattttca gattccacat tgaaagaaat gagccgaata cgtccatcaa
    57541 gcagattgga gatgcttcag ataaaaggag ttggccaaag caagcttgat aaatatggcg
    57601 aagccttttt atctcggata aaaaatgcgg actctaacgt tctggataag tagaaagaac
    57661 gaatacgtaa aaatgaataa aaacaactgg ttaaatctgt tttttttgct ccttatgaaa
    57721 atcaaatatg ttataattaa ggaattagaa tgggaggtaa gcacagatgg attctttgtc
    57781 gaaaaaactt gcgatccaag tattaaatga tgaagcagaa cggatcaaac gattaatccg
    57841 aaatcaaaac aacagtctct gtatctcaca atgcaaagcc ttcgaagaag tggtagatac
    57901 acagatgtac ggcttttccc ggcaagtcgg ttttgctgtc cgtataggag taatcggaaa
    57961 gaacgagggc cagctgatgt taagtgagct agaacgagaa ttgaatcagt tatatagtga
    58021 ggtttaccaa gaaatttatg ataaaaaaga agttggcaag gaggaataga cttgcctaag
    58081 aaagtgaaaa aaaggcatct attagactat agcatcttga ttccctattt aattttatgt
    58141 gtattgggat tgatcatggt atatagttct acgtcgtatc tattattaga aaacggacaa
    58201 aatccgtccg catcagtcat taaccagagt attttttggg tgcttagctt gattgctatc
    58261 gcactacttt ataaaatgaa aacagatgtt ttgaaaaacc agcgtttgat catggcagcc
    58321 atcgcagttt tgacgatttt gctgctgatt gttgtgtttt ttggtaagga gatcaatggg
    58381 gcgaaaggtt ggctgcaaat tgcaggattc tcgatccaac ctgccgaata cctaaaaatc
    58441 atttctatct ggtacctgtc tctgacttta tctaaaagac aaaacagtgt acaaaaagat
    58501 tttcttggga ctgtgaaacg tccacttgca atggttatcg gacttactgc attagtcgct
    58561 attcttcccg attttggtaa tgcggcagtt atctttttga ttattttggt tctgctttta
    58621 gccagcggag tcaattatgt gtatactttg attgtaggag taggaggctt ttgtctaagt
    58681 acttttacga tctggctgat caatatcaca aacggaaaga tcttacccgg acgtttacag
    58741 tatatctata atcgatttgc tatttaccaa aatcctttct cagacgaatt aaataaaggg
    58801 catcaactag tcaacggcta ctatgccatg ttcaacggag gactatttgg caggggatta
    58861 ggtaacagta tccagaaaaa aggattttta caagaagcac aaaccgattt tatttatgca
    58921 atcgtagtgg aagaactggg agtgattatg gggattttga tattagcgtt gctattcttt
    58981 atgattgtgc gcattgtcct tgtaggtatc cgttcaaaag atccgttcaa ttcgcttttg
    59041 tgcattggga tcggcgcaat gtttttgatc caagtatttg tcaatcttgg aggaattact
    59101 ggcgttattc ctttgacagg gatcacgttc ccatttttaa gtcaaggagg ctccagtttg
    59161 ctgatgcttt cgatttgtgt cggctttgtc ctcaacatca gtgcggatga aaaacgcaag
    59221 agcttaggtt tataataaaa aaagatgtag gagtggttcg atgaaaaaag ttttagttgc
    59281 taacaggggt gaaatcgctg tacgtgtatt tcgtgcttgt acagaattag gaattaaaac
    59341 tgttggaatc tatgcagaag aagatgaata ttccgtacac cgtttcaaag cggatgaagc
    59401 atatttagta ggacaaggaa aaaaaccgat tgatgcgtat ctagatattg aagggatcat
    59461 ttctatcgcg aaagaatgcg gagctgacgc tattcatccg ggttacggtc ttttgtcgga
    59521 aaacttgaat tttgcgcaac ggtgcgaaga agaaggcatc atttttgttg gacccaaact
    59581 gcatcattta gatatttttg gagataaaat caaagcaaaa gctgcagcta tcgaagcggg
    59641 gattgcttcg attccaggca cagatggacc aatcgcttct atagacgatg ccttggagtt
    59701 tgcgaaacaa tacggttatc cgattatgat caaggcagct ctaggcggcg gcggacgcgg
    59761 catgcgtgta gctcacgatg aaaagagtgc aagagagggc tacgaacgtg cgaaaagcga
    59821 agcaaaagca gcctttggta gtgatgaagt gtatgttgaa aaatacatcg ctaatcctaa
    59881 gcatatcgaa gtacagattc tcggggatac gcatggaaac gtcatccatc tttttgaaag
    59941 agattgttct gttcagcgcc gtcaccaaaa agtagtagaa gtagcgcctt gtgtctctat
    60001 gaatgaacag caacgtcaaa aaatctgcca ggcagctgtc caattgatga aatatgtcgg
    60061 gtatgtcaac gcaggtacag tagaatttct tgttgaagga gatgattttt actttatcga
    60121 agtcaaccct cgcgtccaag tggaacatac gatcacagaa atgattacag atattgatat
    60181 cgtaacaacg caactgttga ttgctcaagg tttggatctg cataaagaaa tcggattgcc
    60241 tcagcaagaa ggaattaaat taaatggttc agccattcaa tgccgaatca ctacagaaga
    60301 cccgttgaat aactttttac cagacacagg gaaaatcgat acgtatcgtt cacctggtgg
    60361 ttttggcgta cgtctggatg tcggaaatgc ttacgcgggc tatgtagtga caccgtattt
    60421 tgattcattg ctagtaaaag tatgtacgca tggtgctacc tttgaaacag ccattcagaa
    60481 aatggaacgt tgcttgaaag aatttagaat ccgtggagtg aaaacaaaca ttccatttat
    60541 gctcaatgtc atcacacatc ctgaattcca atcaggaaat gcaaaaacaa ccttcattga
    60601 tagtacagca acattatttg aatttcctcg actacgagac cgcggaaaca aaacgatgaa
    60661 atatatcggt gaaattactg tgaatggttt tccaggtatc gaaagtggcg aaaaaccatt
    60721 ttatgaagaa ccacgtatgc ctaaagatct aatcacaaga actgattacg taacggctaa
    60781 gaatgtatta gatgcgaagg gtgccgatgc tttggtcgaa tggatcaaag gacaggaaaa
    60841 tttgttgttg acggatacga catttagaga cgcccatcaa agtctgctag caactcgtgt
    60901 tcggacaaag gatttcaagc agattgcacg tttgactgga gaaggtcttc ctgaactctt
    60961 ttcaagtgag atgtgggggg gagcaacatt tgatgtggct taccgctttt tgaatgaaga
    61021 tccttggcaa cggttgagaa aaattcgttc tttaatgcct aatacgttgc tgcaaatgct
    61081 tttcagaggt tcaaatgccg ttgggtattc taattatcct gacaatgtat tggtggaatt
    61141 tgtcaaagaa gcagcagcgc aaggaatcga tgtatttcga atctttgata gtttgaactg
    61201 gactccacaa atggaaaaaa gtatccaagc tgtacgggat actggtaaaa tcgcagaggc
    61261 agctatttgc tatactggcg atatcaacga tccaagtcgg gcaaaataca atgttcagta
    61321 ttataaagac atggcaaagg aactagaaca actgggtgcg catatcattg caatcaaaga
    61381 tatggctggg ctgcttaaac cgcaggcagc ttatcgtttg attagtgaat tgaaagaaac
    61441 gacagatctg ccaatccatc tgcatactca tgataccagc gggaatggaa tcatcactta
    61501 ttctgctgct tcaaaagcag gagtagacat cgttgacgtg gcaatgagtg caatgagtgg
    61561 gaatactagt cagcctagca tgagcagctt gtattatgca ctggtcaatg gtccacggct
    61621 gccagaaatc acgattgaaa atgcacagaa attaaaccat tattgggaag atgtgcgcat
    61681 gtattacaaa ccgtttgaaa acggcttgaa tgctcctgaa acagaagtat atatgcatga
    61741 aatgccagga ggacagtatt cgaatctaca gcaacaggca aaagctgtcg gattaggtca
    61801 tcgctgggat gaaatcaaac aaatgtatca tactgtcaac ttgatgtttg gcgatatcgt
    61861 taaagtaact ccatcatcta aagtagttgg agatatggca ctatttatgg tccaaaatga
    61921 tcttacagaa gaagatattt atgaaaaagg cgaaacacta agtttccctg aatctgttgt
    61981 gactttcttc caaggagaac tagggcaacc cgttggcgga tttcctaaaa aattgcaaaa
    62041 gattattctt aaaggcagac ctgcattgaa tgaacgtcca ggtcttttgg ctgaatcagt
    62101 cgacttcaac gaagtaaaaa aagaattggc agaaaaaatt ggctatgaac caaaacaaga
    62161 cgaagtatta agctatttga tgtatccgca agtctttttg gactatcaaa aagcatataa
    62221 tcaatttggc gatgttacat tactggacac accaacattt ttccaaggta tacgtttggg
    62281 tgaaacaatc aatgtacaaa tcgaacgcgg aaaaacgctt atcattcgtt tagatgaaat
    62341 cggagaaccc gatatcgaag ggaatcgcgt actgttcttc aatttgaatg gacaaagacg
    62401 tgaaatcact atcaaagata attcgatcat cagtacggtc caaacccgat tgaaagctga
    62461 accgacaaac cgagaacaaa ttggagcaac gatgtctggt tctgttttgg atgtattagt
    62521 gaaaaaaggc gataacgtta aaaaaggtga tacgttgatg attactgaag cgatgaaaat
    62581 ggaaacggcc atcgaagcac gttttgacgg agaagtcgca catgtatatg tgtcttcagg
    62641 agacactatt tcgtctggtg accttttgat tgaagtgact gagaaataat aagcgaaagg
    62701 tggggaaaca tgaaaagact gggtttgttt tggctgattc tgctattagt tattgtggca
    62761 ttctacatgg aaccagtctt gtttccgcca aaacttgaag tgaaggaaaa ctctgatcaa
    62821 caaatatcaa accaaatgac aacgtggaaa taccaggagc ttaaagcaac tggtttttct
    62881 acttatatcg gaaaaccgat cgatcagctg gaaaaggatt ttggccaagc ctatgatcga
    62941 ttaactagcg gatttggttt tgaaacaaga tattatgaaa ataaagctag tcatctcaca
    63001 tttgaagcga acatccaaga cagcagagtc acaactgtta aagtactgca aacagggcct
    63061 gctgatatcg cgccgtttta tttagggatg acgatgcaag atcttacgaa aatcactact
    63121 atctatacta atttcacttt tgagtaccat gatacagaag ttggaatcga actaatggaa
    63181 gaggatatga attatcgtcc gctaattgct tttgataacg acacttttgc tattttattt
    63241 tttgatcaaa caacaaacgg cctattttca gttgtgtatt tagataaaga tagtcttttg
    63301 aaactattgc catatcaagt gtttggtgaa ggccttccac attatcaagc agataaatcg
    63361 gctgattggg aatcaatcaa tcgcgttaaa gaacgaaaaa gtacgacttt attaaatatg
    63421 cttagaagag aagacgaact tcccatatac aatcaaacac ttgcctttca aaaccacagt
    63481 cagctgctac tacatgattt tttgacaagg cctgaggaaa tattgtcaga ggaacgtatg
    63541 gctgattggc aaaaatcgct aggcagtgct caaacgacag tgaaattctc actgacgaat
    63601 gatgaattgg agaagttaat cagtaaacaa aaattagaaa atactagtgg gctatttatt
    63661 catccggcga ttgacgctac tttttcgttt ttatattggt acagcgatcc ttacaaccat
    63721 gaccgtttca tggacccggg aacggattct gtaggcattg ctttttctaa agaaaatatg
    63781 ttagtcttat tgcaagaaga aaacggagaa agtagtgata gcagtgatcg ttaacgaaga
    63841 gctgtttcaa ctggaggatc aatgcctcca agtcgctgaa atgataaaaa agagtaaaac
    63901 gatggcttct tatcttgaac ataaacagtc aatggaagaa tctgcaaaag tttgccagtt
    63961 gaaagaagcg ttcttgtcta agaaagaagc atttgaaaat gtagcggcat atggtgagta
    64021 tgcacctgat tatcgtgaaa aaaaacgagc tgttcgaaaa gcaaaaagac agcttgatat
    64081 ggatgagcat gttgcagctt tccgatatag tgaaacacag ctgcaaagtc tgttggatca
    64141 aattgtccaa gtacttgccg aagaagtttc taatgaaatc aaagtagatg caggtagccc
    64201 gttttttgaa acgaaaaaac actttggatg cggaggtaat tgtcatgcaa ttagacaata
    64261 gtgaatttga aataacaaaa cgacgcgggc tgatcgtatg ggtctacagc ttaaaacaat
    64321 taaagaatct gaaaaagttc ggcttgttgc attatgtctc aagaagaatg aaatatgtcg
    64381 tgctttactt aaatgaagag acattggaag aaacagaaga acgaatccgt aaattacatt
    64441 ttgttcgaaa cgtagaacgt tcttaccgac cggatatcga aatgaatttt gccgaaaaaa
    64501 taggaaacaa aacagtatta aaagacgaag gtttcgaaat tgaagagcta aatacagaaa
    64561 tccgattagc tgaacatctt taaaaatctc ttatgagcag tttttaaata aaaaataact
    64621 tggataacga tcgatttttg atcattgtcc aagtattttt ttggtatact agtaccagta
    64681 ccatttctaa ggagtgagta gatgcggata atatcaggaa attatggcgg gcgccgttta
    64741 aaaagtttag caggggcgaa caccagacca actacagata aagtaaaaga atccatattc
    64801 aatatgattg gaccatattt tgatggagag acagtattgg atctgtttgc aggaagcggt
    64861 ggtttagcta tcgaagcagt atctagaggc tgcagtcatg cggtatgcgt agacaaaaat
    64921 taccaagcgc taaaaatcat caaagaaaac atcgaaatta cgaaagaacc agagaaattt
    64981 accacaataa aacttgatgc ggacaaagca atcgaacggc tagcagcgga gaaacaacaa
    65041 ttcgactact tgtttcttga tccgccatat gcaaaacaaa aaataatcga tcaaatccat
    65101 aaaatggaag aactgggact tttttctaaa accgcagtta tcgtatgcga aacggataaa
    65161 acagtcgaat tgccagaaac tgtggctgga ttccatcaaa taagaaaaca gatttatggc
    65221 ataacggccg taactatcta tagaaaagag ggaaatcaat gaaacgtgca ttattcccag
    65281 gaagttttga tccttttaca aaaggtcact tagatacggt ggaacgtgcg gctaaattat
    65341 tcgatgaggt agtaattggt gtttttatca atacttcaaa gaaaagtttg tttcccccag
    65401 aagaaagaat gacattgatc acaaaagctg tttctcatct tcctaatgta aaagtcatgc
    65461 atcaagaaaa tcaattgacg gtagaaacag caaaagagat tggtgcagat gcgttgatca
    65521 gaggcatacg aagtatcaaa gactttgaat atgaacgaga gattgctcag atgaatcatc
    65581 atctatatga tgaattggaa actgtcttct tattagcaaa accagaatat agtcacgtga
    65641 gttccagtat tttaaaagaa gtactgcact ttggcggaga tgtgagcagc tacttaccgc
    65701 cagtgatcaa cgaagcttta gctggaaagc gtgaatcaaa tgaaagctaa acaatggttg
    65761 aaaacagtac tgattatcat atttggaatg ttgatcattg gatttgtagt agttcccttg
    65821 ccgtattatg tagaatcacc gggagccacg atcgatctga aagaactaat tacggtcaat
    65881 gataaggaag ataaaggttc tgggtctttc tctcttacct ctgttggtat caggcaagct
    65941 acaggtttct tagctttaaa agctaaaatg accccttttg aagaattgat cagtgaagaa
    66001 gaattgactg gtggggcgac aaatgaagaa tataatcaaa tgcaacagta ttatatggat
    66061 tcttcccaaa atgcagcaat cgaacaagcg ttaaaacttg cagacaagcc ttataaaatg
    66121 gaattcaaag gcgtatatgt catgagtgta gagaaaacat cgaatttctt tggcaagctt
    66181 tcagttggag atacagtaac aaaagtagac gggaaaagct ttcaaagtac agaagcattt
    66241 atggattatg taaaaagcca aaaagttgga caaacaatcg aaatcagtta tttgcataat
    66301 ggtgaagaaa aaacagcttc tggtgatctg atcgagttac caacagataa aaaggcagga
    66361 ataggtatca cgcttactga ccataccgag atcgaatcag atacagatgt tcgtattaat
    66421 tctggctcta tcggtgggcc atcagcggga ttgatgttca ctttagaaat ctatgaacaa
    66481 gtcactggta aaaacttgcg acatggtaag caaattgcag gaactggaac gatcaacagt
    66541 gaaggagaag ttggccgaat cggaggaatc gataaaaaag tggcaagtgc ggataaagct
    66601 ggcgtagaga ttttctttgc accagatgat acgatttcag acgatgttaa gaaagaatat
    66661 cctgaaataa aaaccaacta cgaagaagca aaagctgccg ctaaaaaatt gaattcctca
    66721 atgaaaatcg taccagtaaa aacagtacaa gaagcgcttg actatctaga gaaaatgaaa
    66781 tgaaactaaa taattaaaga ggggttgtga cacgagttct gtcacaaccc ctctttttcg
    66841 tcaaaaatct tcacgataaa aataaaaaca aaagaaaaaa ttgacgtaat tagatgttga
    66901 agggacgatt ttgccagagc tcactgtttc ttcaatttta aatgaaagga gtaatgaatg
    66961 atttttactg gtcattcttt gaaaaaagaa caatgataga aaaaatcagc aagaaaatac
    67021 tagcttcacc caaattgatc atttggatgt ctatgatagt tcttatcttt tgtatcgcaa
    67081 gtggtttttt attatcaaat ttgctatttt atagagaaac agaagagact gctgcaaaag
    67141 aaatactttc ttcgtttagt tccagtggag aagatccatc agctgaagga aacgatgtag
    67201 aagaggatgc tcgtccaaag gtcatgtaca ccgatatcaa aggaagtgtg aaggagcctg
    67261 gtatctattc cttttcttca gaagaacggg tctatgatgt actaaagcgt gcaggtggat
    67321 tattagaaga agcggatagc gatcgaatca acttttctgc gaagatagaa gatcagcaag
    67381 tcctatatat ccctgctgta ggtgaagagc tgccagaaca tcttgatcag ttggcatcct
    67441 cggaaggaaa acagcctaca gcagattccg agcctcccaa aataaatatc aatacagcca
    67501 ctccatcaga acttcagcag attcctggga tcggatcagt caaagcgcaa gaaatcattc
    67561 gatttagaga agaaaacgga tccttccaga aagtggaaga cctgcaggag atttctggta
    67621 tcggtgaaaa gacagttgaa aaactaaaaa acttcgttac aattaaatag aatgattcaa
    67681 aatcgactgg cacgagcaat aaatggacgc taatggatac taagaataat ccaattctaa
    67741 gagcttggca ggacgaggag gtagtatttt tggataggaa atagcttgat tgttcgcaaa
    67801 gaaacattaa aaaaaccaat gctgaatgtc tatctccaaa ataaaatatc tgggattcat
    67861 attatgaata cggctgtcag cggcaataac agtcaagctc tacgagaacg ctttgccaaa
    67921 gatgtactta gctatacagc agataaagta tttattctca ttgggacgaa tgatctagca
    67981 gagcataaac aactttctaa agaaacgtac caaaaaatct gcagtggatg atagttcagc
    68041 tgaaaaaaga ctatagttct gatcatgctt tctttatcac gccaccagca gtcgatgaga
    68101 caaaacaaaa atatcggaat aacaagttga tcaaagaata tatctctgtt ctcacagaag
    68161 tagcaaaacg ccatgattgt gaagtatcga tttttatacg gaatttcttg aacaaatgga
    68221 ttcgaagaat ttttataatg ggctaatgga tgacggactt catttcggca gtgaagggta
    68281 ggatcttttg tcagacagga tgattcgtta tatttaaaga atattttgtt taagcaatga
    68341 gtacttttta atcaacttga aaaaacggag gaatataaaa catgttagaa aaatcttcaa
    68401 aagcatgcga tacgaataaa gaaaaagtta ctgataagtc acataatgaa cgcattcctt
    68461 gggaccagta ctttatggct caggcagtac tgttatcttt acgtagtacg tgtacacgtt
    68521 tagaagtagg agcgacactc gttcgagaaa aaaggatcat tgctggcggc tataatggag
    68581 cagtcagtgg agatgtccac tgcatagatg aagggtgtta cgtcgtggat ggacactgct
    68641 tgcgaacgat ccatgcagag atgaatgcac tcctacagtg tgcaaaactt ggtatcccga
    68701 cggaaggttc agaaatctat gtcacacatt ttccatgttt ggcctgtaca aaggctttgt
    68761 tgcaagctgg tgtgaaaggg atcaattatc tccatgacta tcgaaatgat ccttatgccc
    68821 aagcgttgat cgaacaatta ggtgtatctg tacaccaagt tgctttagac tcacagcatt
    68881 tttcaaaact tcaaaatgaa ttaacaggaa aacatgtcta gcgttttaga aaggcatgtt
    68941 cgaaatcggt tgatttttcc ggcaattacg tcgatgatta tctgtttgtt gtattacact
    69001 gacaattggg gttatcgttt gcttcttgcc ggaatttttt tatggttttc gctaaaagaa
    69061 ggacgtttta tcgcgtactt gtgtattttg tgtagcataa cggtatccat ttcttatagg
    69121 ctacaagagt attcattttt agaggaaaaa acaacatctg cgcaaattac tgtatttaca
    69181 gatacgattc gtgcaaatgg taattttttg acaatggaag gaaggttatc agagaataaa
    69241 caaaagctcc agctttctta tcaagtaaac acagaagcag aattgaaaac atggcttaac
    69301 ttccgaggaa agggaataga attgactgct gaaggcgagt tcatctctcc agcaaaaaag
    69361 cggaatcttt ataattttga ccaagaagct tacttcagga accatagaat ttctggacgg
    69421 ttccaaattc aaaagattga acagatcacc atgcaaaatc actggcgaaa ctggcttcag
    69481 agaaaaagag gatcttttat ctcctttgtc caatctgaat ttccgcaaaa aacaagtgta
    69541 tatattaatt ctttattatg gggctataaa gatgcaggat tcagagaacc agaagaaatt
    69601 tttagggaga gtggtttgct gcatctgttc agtctatcgg gtctacacat ccaattttat
    69661 ttagggtggc tgtattattt atttcgacgt atcggatggc cactacacgt cagtattatt
    69721 ccgttgagtc tactaactat ctgttatgtt tctattgcag gaagttctat ttctgttttg
    69781 cgtgctagtt tgctgttttt attgcgattg ctagtcaaat tgctgaataa gcattattcc
    69841 accatggact tatttgcagt tgtcttttgg cttcttttac tatttgatcc tcgatttctt
    69901 tttcatgcgg gtggacagct tagttttttc atgagttttt tgtttatcct gatttctttt
    69961 gatggagatt ggttgaaaaa aacggcctct cacgtcctgt ttactatgat cacgatgccg
    70021 ttgattgtat ggcattttta tgagtggcct attttaggta gtctttttac attactgatt
    70081 gcaccggtat tcaagtttct ttttcttcct ggtgtgttat ttctcacact cttcaatcgc
    70141 tggctgccgg aaactttact tttgctgata gaagagggat taatcttatt tgagcgaata
    70201 atcgattttt cttcagggtc gtctctcatt ataggacgtt tgccccttgt gctatctggg
    70261 atgtatattt tcggattact gatttgtatg gataggttga aagaacaacc tgtgaaacac
    70321 ttgttttatg ttggtctttt ttcttttatt tttttgactt tgccattttt acgcttttct
    70381 tcaacgatcg cttttatcga tgtcggtcaa ggagacagta tctttttgca aagtcctttt
    70441 cgaaaagaaa cgattttgat cgatactgga ggtcagttac actttgaaag agaaaagtgg
    70501 gcgcaaggta tgatacgtcc tcctgctgaa agaaatatcg ttccatatct aaaaggtcag
    70561 gggataagtg taatcgataa actcatcttg acacacgacg atacggatca tgtgggagaa
    70621 ttacccacgt tatctcagca ttttactatc aaaaaaattt atatcggttg gggcgctgga
    70681 cgaaatgagc cattacaaag gcatttatct gaagctcaaa aaaatggtac tgagatcatt
    70741 gaaatcaaac atggggacag gatcagcggt tattatgatc tttatgtatt gactcctttt
    70801 gaaaagggag agggaagaaa tgaagattcg attggtctat ggatggaata taacaatagg
    70861 cgctttttat ttttaggaga tttgaatcaa gcaatggaaa aacaattgct tttgatttat
    70921 cctaatctga aagccgatgt agtcaaatta ggtcatcacg gtagccgtac gtcaagtaac
    70981 acagattttc tttcccatat tgaagcaaaa catgggatta tatcctgcgg cgtaaataat
    71041 cgttatggtc acccgcacag cgaagtattg gagacactag aagaaaatca gataaaaaca
    71101 tggcgaacgg atcaacaagg aatgatcacc tatcgctggc atccagtttt tcatcctcat
    71161 gggctagtgg aaacaatgat agactagtaa ttctcatctg ctcatggtag gataattttt
    71221 gaaagtggtg agtaatttga gtatacaagc agagttacaa aaaatacgta aagaaaaact
    71281 tgcatcttgt tacttgattt taggaacaga aaagtttctc caagatcaag ttcggacaga
    71341 aattgtcaaa aaaatccaat tagagggcga agatgactta aattttttaa gttttgacat
    71401 ggaaaatgca agtttagatg aggtagtagc tgaagcagag acgttgccgt ttttcggaga
    71461 tcaacggtta gtattcgtag agaatcctta ttttttaaca ggtgaaaaag taaacaatgg
    71521 aatcgaacaa aatactgatt tattgacggc ttatttgaaa gaaccattag aatcgactgt
    71581 attagtattc tttgcgccat atgaaaagtt ggatgaacgg aaaaaagtaa cgaaacaatt
    71641 gaaaaaaaca gcaattatca tcaatgtcca acagttgaat gaaaaagaag tacgtcaata
    71701 tctgatgaat accttagaga attcctcaat caaaatggaa cgaagtgcaa ttgatttatt
    71761 cttgaggttg accgacttag atttatccaa aatgatgaga gagttacaga aattggtcct
    71821 ttatggacaa aatcaacagc aaatcacggt aagagaagta gaagaattag ttcctaaaac
    71881 gttagaacat aatatttttg acatgaccca atatatttta aaagggaaga cggaacaagc
    71941 tttgcgttta tacgaagatt tagttatgca aggggaagaa acaatcaaaa ttaatgcgat
    72001 tttgctttct caattacgtt tatttttaca gacaaaattt cttgtaaaga ttggttatca
    72061 gcaggcaaat attgctgaaa cattgaaaat ccatccatat cgtgtaaaac ttgccatgca
    72121 ggaagtaaaa aaattcgatg aacatttgct ggtacagttg tttgatcaat tagttgagat
    72181 ggattatcaa atcaaaacgg gacaaatcga aaaagaatta agttttcaac tattcgtttt
    72241 gcgcacaggg cagttgttaa gaaatcgata agaagaaaga cgagggcaaa gcatgcggga
    72301 aggtcgtttg tttttgtcct ttttttgaca aataaaaaaa tcggccgaag ccgattcttt
    72361 tatttagcga tttttttgct taaacgagat ttgtcgcggt tagctttgtt tttgtggatt
    72421 agaccttttg attcagccat atcaatagct ttaacagctt ctttatataa cgcatctacg
    72481 ttgtcagcac ctgaagctac agcatcttca aattttttga ttgcagtacg catagcgctt
    72541 gtttgagatg aatttttcac attagcgttt tcgcttgtac gaacacgttt gattgcagat
    72601 tcaatgtttg gcattagttt cacctccgat aacttaagtt cttacgcgtg ttaccgcata
    72661 attcaacatt cattattata cctaaaggca gcgtgctttg caatatgaac atgacaagtt
    72721 tttttcctta acagtctttt attaggattt tttttcagta aaaacggata gtacaagctg
    72781 aaaaaaatca aaaagacgct attgtgggag gcaatagcgt caaaccaaac tagattttta
    72841 tttatctatt taaacaaagt ttgaatggga atgtttggta ctaagttatt atataacaaa
    72901 gagaaccgtt tgcaaagttt tttttgaaaa gggatacgat tccctgttgt tctttgtttt
    72961 tctattaaga aactgcagtt attttataac cagtatcctt tgatcagtaa aggctattct
    73021 ggtgtaccga ttattttaat gtattcatcg atatttttta tcaacatttt ttttatgacc
    73081 aactggttcc gacggttcca tttgccactt acttccagca catatttatt taggggcaaa
    73141 cgtaagatat attttgccaa atagcgatct ttaagcaggc cattgatcac acggtcctca
    73201 agctgcaagt tgatcccagt cagcatcatt ggctgttctt gtaaaacgta cgtatcaatt
    73261 aaaagacctt caaaagtttc cacaagcgtc ttcctttctt ttcaaagtaa cctgaaaaca
    73321 ggcactaatt cttccatttt gatattcgtt gaagtggatg cgatcattct ttcttttgtc
    73381 cactgtaatc tagtataaca aaaaagagca gaagagccaa aaagaaaaaa gagcatcgaa
    73441 ttctatagga agtctcattg gcacggccta aattattaca aaacattgat taaaaaaagc
    73501 ccctgcatcg caggagcatc ccctatatcg ttttaatagg tcaatcaaaa agcagtatca
    73561 aacacatttt gtatcaaatc aggaaataat agataagcta agcccagaat caaaagtacc
    73621 gctagaagaa accagccgat tgttcctatg aaatacttta atttttcgaa cattgtatca
    73681 cctcgttgtc agtatatcac ggatcagtaa attgggggtg ttaagaatct cctaaaatag
    73741 acaaaatttg ttctattttc ctaaagcaaa tacttgtaag atacagtaag tgataccaga
    73801 agcaatgacc ggtccggcgg cgattcctct taagaagaca acacctaaaa tcgtgccgaa
    73861 aacaagtgca acagtgattt gtggatcaga agcaatcaat cctacaccct tggaagataa
    73921 gacagccact agcccaccgc aaaaaacagc tacccagcca ataggggatt taaaggcttc
    73981 taatagatca cgtagaccga tttctcctgt tgcgataggg attagaatag ccgctgtgat
    74041 gatcgtcacc ccaatattga ttcctttgcc ttgaagccaa gggaaaaagg aacgggaggc
    74101 tggtatgagc ttcataatca aaacaaaagc tgccgctatc atcagacttt gatttttagc
    74161 taaaattgct acaagtaaaa taattcctaa aaaaagccaa ctttccatga aatatattcc
    74221 tcactttctt cgaaacaatc ataacatgtt tttagaaagt tacaaaagta ggaattcatc
    74281 cttcaagacc tattcataag ctgttttttt cataaaataa acaaaatcat aaaaaaacac
    74341 tttgcttatt tgacagaaga cagccgcgct ttgtatagtg gacaagactt acattttttt
    74401 gaagaatcag aaagatcagg taaaggtctt agtaaacgca agccattcag aataaccaat
    74461 attgtgcttc cttcgtgtcc tacaactcca agaggtagat ttaaaaattg caggaagtta
    74521 gaagcaatca acaagagaat aacaagaatc gaaaaaataa tattttgttt gatgatccgc
    74581 cgcattttta aagatagccg atgactgtag acaaatttat ttaagtcgct tttcattaag
    74641 acgatgtctg cgatatccat agcggcatct gtcccttgcc ccatagcgac acctaaagaa
    74701 gcggctgcta aagcaggcgc atcattgact ccatcaccaa ccatcgcatt tacttggtaa
    74761 agttcattct cttttttgac tagttgtgtt ttttcttccg gagtacagct tgcatagtaa
    74821 tgttcaatcc ctacttgttc agcaatggcc tttgctgtgc cagaatggtc gccggttatc
    74881 atacttgtat ggatgttttg ggatttaaag taggaaatta cttgttgggt atttgctttt
    74941 ggaatatcta gcagacctaa aacagcaatt aactgctgat ctttagaaag ataaatcacg
    75001 gttttgcctt gattttccaa acgttcgatc atttccgcaa tctctttgct gattatcatc
    75061 gtctcaggat catatgcgtg cttgccaact ttccattgcg cacctaaata ggtagtttgt
    75121 aatccaaaac cagtaatttc ttctattggt aagtattgga tttcttcagg tattgtgcaa
    75181 tcgaaatatt gcaaaatcgc atgagcaagt ggatgcgtcg ttttttgttc catagcaaca
    75241 agaagttgtt gtgccaaatc cttttcatca aagaaaaagc tgtcagttac aactggtttt
    75301 cctttagtga gcgttcctgt tttatcaaag gcaatcgctt ttaattcaga aagcttttct
    75361 aaatggatac cgcctttgat taaaatccca ttttttgcag aatttgaaag agcagctaga
    75421 gaagctggtg tagcagatgc gacaagcgca caaggagaag ccacaactaa taataccatt
    75481 cctcgataaa agctttcatc ccaactccaa cctaggaaaa agtgggggag aaggatcatt
    75541 agaggaacag caagcaaaat caattttaca taattatttt cgattcgttc gataaatgaa
    75601 gctgtttgag ttggcgtatt ctgcgcttct tctactaatt ggataatctt agcaaagaca
    75661 gtttcggaac tcgtttttgt tactcgaatc gtgatgggat ttccttgatt cagcgttcct
    75721 gcatacatct catcgcctaa atatttttct acaggcacag attcaccgct taatgcagac
    75781 tcatcgatcg ttgcctgtgt gctttctaaa aagccatcta tcggaacagc tgctccttta
    75841 gcgacaaata ccaagttatc cacctttagt tgagaaacat ctacttcttg catttgtcca
    75901 ttttctttta ataattgggc tttttgtggt tgaagattca tcaaagcagt aatttctttt
    75961 tgacttttat tagttgtgta ttcctctaat gcaccgctta aacaaaagat gaatgtcaac
    76021 attgctcctt caaagtaatt accgatcaaa caggcaccaa tagcagctaa agccatcaat
    76081 aaatccacat tcagtgtccg atcattccac aattctttca agccttccga tgtttgttta
    76141 tatccaccga tgataatggc actgatataa aaaagtgggg tgatggtaag agagaatcgg
    76201 tcgaagataa aaccgaagat cataaataaa aggcagccga ttgttgctgc aaaagctttt
    76261 ttctgattag tcatcgttat tagacctcct tgtcaaaaca aggatagcat aataaaaatg
    76321 taattgataa taataacagc taaatgagaa cgataatggt tatcatttgg tgattaagct
    76381 tgatgttgtt tttattattt ataatgatta ttattaaaga aaataaaaaa ccagaacatt
    76441 tctcaaataa ga
//
LOCUS       DARBDN010000004        68436 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000004 DARBDN010000000
VERSION     DARBDN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68436
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.004"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..739
                     /locus_tag="SCH06_000267"
     CDS             <1..739
                     /locus_tag="SCH06_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEG1076873.1"
                     /translation="SLLIKTLERKSSSNYYEGGNEIVSKMKISEVTLDETDDFTYYKG
                     YKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGDNVLVDTILVPLPEN
                     YEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHGYLIEILKKYEITVP
                     RDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRHSLAHPNTN
                     IIGKREAKLIIGISSTVTDYISGYLDK"
     gene            806..1300
                     /locus_tag="SCH06_000268"
     CDS             806..1300
                     /locus_tag="SCH06_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEG1076874.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            1356..1994
                     /locus_tag="SCH06_000269"
     CDS             1356..1994
                     /locus_tag="SCH06_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076875.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            2066..2461
                     /locus_tag="SCH06_000270"
     CDS             2066..2461
                     /locus_tag="SCH06_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1076876.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            2445..4898
                     /locus_tag="SCH06_000271"
     CDS             2445..4898
                     /locus_tag="SCH06_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1076877.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            4895..6922
                     /locus_tag="SCH06_000272"
     CDS             4895..6922
                     /locus_tag="SCH06_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076878.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            6919..7941
                     /locus_tag="SCH06_000273"
     CDS             6919..7941
                     /locus_tag="SCH06_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEG1076879.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            7958..8887
                     /locus_tag="SCH06_000274"
     CDS             7958..8887
                     /locus_tag="SCH06_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1076880.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            9132..9248
                     /locus_tag="SCH06_000275"
     CDS             9132..9248
                     /locus_tag="SCH06_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEG1076881.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            9264..10067
                     /locus_tag="SCH06_000276"
     CDS             9264..10067
                     /locus_tag="SCH06_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEG1076882.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            10302..10538
                     /locus_tag="SCH06_000277"
     CDS             10302..10538
                     /locus_tag="SCH06_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076883.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            10545..12497
                     /locus_tag="SCH06_000278"
     CDS             10545..12497
                     /locus_tag="SCH06_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HEG1076884.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(12569..13066)
                     /gene="dfrG"
                     /locus_tag="SCH06_000279"
     CDS             complement(12569..13066)
                     /gene="dfrG"
                     /locus_tag="SCH06_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HEG1076885.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            13428..14468
                     /locus_tag="SCH06_000280"
     CDS             13428..14468
                     /locus_tag="SCH06_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEG1076886.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            14566..14754
                     /locus_tag="SCH06_000281"
     CDS             14566..14754
                     /locus_tag="SCH06_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEG1076887.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(14812..15165)
                     /locus_tag="SCH06_000282"
     CDS             complement(14812..15165)
                     /locus_tag="SCH06_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076888.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            15696..16118
                     /locus_tag="SCH06_000283"
     CDS             15696..16118
                     /locus_tag="SCH06_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEG1076889.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            16115..16345
                     /locus_tag="SCH06_000284"
     CDS             16115..16345
                     /locus_tag="SCH06_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076890.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            16843..17043
                     /locus_tag="SCH06_000285"
     CDS             16843..17043
                     /locus_tag="SCH06_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEG1076891.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            17070..18263
                     /locus_tag="SCH06_000286"
     CDS             17070..18263
                     /locus_tag="SCH06_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1076892.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(18331..19896)
                     /gene="guaA"
                     /locus_tag="SCH06_000287"
     CDS             complement(18331..19896)
                     /gene="guaA"
                     /locus_tag="SCH06_000287"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEG1076893.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(19955..20878)
                     /locus_tag="SCH06_000288"
     CDS             complement(19955..20878)
                     /locus_tag="SCH06_000288"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEG1076894.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            21074..21679
                     /locus_tag="SCH06_000289"
     CDS             21074..21679
                     /locus_tag="SCH06_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEG1076895.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            21987..23003
                     /locus_tag="SCH06_000290"
     CDS             21987..23003
                     /locus_tag="SCH06_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEG1076896.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            23144..24445
                     /locus_tag="SCH06_000291"
     CDS             23144..24445
                     /locus_tag="SCH06_000291"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEG1076897.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            24491..25153
                     /gene="deoC"
                     /locus_tag="SCH06_000292"
     CDS             24491..25153
                     /gene="deoC"
                     /locus_tag="SCH06_000292"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEG1076898.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            25174..25572
                     /locus_tag="SCH06_000293"
     CDS             25174..25572
                     /locus_tag="SCH06_000293"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEG1076899.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            25638..26720
                     /locus_tag="SCH06_000294"
     CDS             25638..26720
                     /locus_tag="SCH06_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1076900.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            26932..28494
                     /locus_tag="SCH06_000295"
     CDS             26932..28494
                     /locus_tag="SCH06_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076901.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            28487..29620
                     /locus_tag="SCH06_000296"
     CDS             28487..29620
                     /locus_tag="SCH06_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076902.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            29620..30576
                     /locus_tag="SCH06_000297"
     CDS             29620..30576
                     /locus_tag="SCH06_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1076903.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            30675..31841
                     /gene="deoB"
                     /locus_tag="SCH06_000298"
     CDS             30675..31841
                     /gene="deoB"
                     /locus_tag="SCH06_000298"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEG1076904.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            31865..32683
                     /locus_tag="SCH06_000299"
     CDS             31865..32683
                     /locus_tag="SCH06_000299"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEG1076905.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            32700..33407
                     /gene="deoD"
                     /locus_tag="SCH06_000300"
     CDS             32700..33407
                     /gene="deoD"
                     /locus_tag="SCH06_000300"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEG1076906.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(33705..34391)
                     /gene="gpmA"
                     /locus_tag="SCH06_000301"
     CDS             complement(33705..34391)
                     /gene="gpmA"
                     /locus_tag="SCH06_000301"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEG1076907.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(34563..35144)
                     /locus_tag="SCH06_000302"
     CDS             complement(34563..35144)
                     /locus_tag="SCH06_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1076908.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(35277..35960)
                     /gene="rpiA"
                     /locus_tag="SCH06_000303"
     CDS             complement(35277..35960)
                     /gene="rpiA"
                     /locus_tag="SCH06_000303"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEG1076909.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            36279..36692
                     /gene="rpsL"
                     /locus_tag="SCH06_000304"
     CDS             36279..36692
                     /gene="rpsL"
                     /locus_tag="SCH06_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEG1076910.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            36776..37246
                     /gene="rpsG"
                     /locus_tag="SCH06_000305"
     CDS             36776..37246
                     /gene="rpsG"
                     /locus_tag="SCH06_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEG1076911.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            37340..39427
                     /gene="fusA"
                     /locus_tag="SCH06_000306"
     CDS             37340..39427
                     /gene="fusA"
                     /locus_tag="SCH06_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEG1076912.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            39599..40786
                     /gene="tuf"
                     /locus_tag="SCH06_000307"
     CDS             39599..40786
                     /gene="tuf"
                     /locus_tag="SCH06_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEG1076913.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            41193..41501
                     /gene="rpsJ"
                     /locus_tag="SCH06_000308"
     CDS             41193..41501
                     /gene="rpsJ"
                     /locus_tag="SCH06_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEG1076914.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            41532..42161
                     /gene="rplC"
                     /locus_tag="SCH06_000309"
     CDS             41532..42161
                     /gene="rplC"
                     /locus_tag="SCH06_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEG1076915.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            42189..42812
                     /gene="rplD"
                     /locus_tag="SCH06_000310"
     CDS             42189..42812
                     /gene="rplD"
                     /locus_tag="SCH06_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEG1076916.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            42812..43102
                     /gene="rplW"
                     /locus_tag="SCH06_000311"
     CDS             42812..43102
                     /gene="rplW"
                     /locus_tag="SCH06_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEG1076917.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            43141..43974
                     /gene="rplB"
                     /locus_tag="SCH06_000312"
     CDS             43141..43974
                     /gene="rplB"
                     /locus_tag="SCH06_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEG1076918.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            44017..44295
                     /gene="rpsS"
                     /locus_tag="SCH06_000313"
     CDS             44017..44295
                     /gene="rpsS"
                     /locus_tag="SCH06_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEG1076919.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            44318..44665
                     /gene="rplV"
                     /locus_tag="SCH06_000314"
     CDS             44318..44665
                     /gene="rplV"
                     /locus_tag="SCH06_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEG1076920.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            44679..45335
                     /gene="rpsC"
                     /locus_tag="SCH06_000315"
     CDS             44679..45335
                     /gene="rpsC"
                     /locus_tag="SCH06_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEG1076921.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            45338..45772
                     /gene="rplP"
                     /locus_tag="SCH06_000316"
     CDS             45338..45772
                     /gene="rplP"
                     /locus_tag="SCH06_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEG1076922.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            45762..45950
                     /gene="rpmC"
                     /locus_tag="SCH06_000317"
     CDS             45762..45950
                     /gene="rpmC"
                     /locus_tag="SCH06_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEG1076923.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            45975..46241
                     /gene="rpsQ"
                     /locus_tag="SCH06_000318"
     CDS             45975..46241
                     /gene="rpsQ"
                     /locus_tag="SCH06_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEG1076924.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            46299..46667
                     /gene="rplN"
                     /locus_tag="SCH06_000319"
     CDS             46299..46667
                     /gene="rplN"
                     /locus_tag="SCH06_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEG1076925.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            46704..47012
                     /gene="rplX"
                     /locus_tag="SCH06_000320"
     CDS             46704..47012
                     /gene="rplX"
                     /locus_tag="SCH06_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEG1076926.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            47040..47579
                     /gene="rplE"
                     /locus_tag="SCH06_000321"
     CDS             47040..47579
                     /gene="rplE"
                     /locus_tag="SCH06_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEG1076927.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            47598..47783
                     /locus_tag="SCH06_000322"
     CDS             47598..47783
                     /locus_tag="SCH06_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEG1076928.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            47819..48217
                     /gene="rpsH"
                     /locus_tag="SCH06_000323"
     CDS             47819..48217
                     /gene="rpsH"
                     /locus_tag="SCH06_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEG1076929.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            48249..48785
                     /gene="rplF"
                     /locus_tag="SCH06_000324"
     CDS             48249..48785
                     /gene="rplF"
                     /locus_tag="SCH06_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEG1076930.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            48946..49302
                     /gene="rplR"
                     /locus_tag="SCH06_000325"
     CDS             48946..49302
                     /gene="rplR"
                     /locus_tag="SCH06_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEG1076931.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            49323..49823
                     /gene="rpsE"
                     /locus_tag="SCH06_000326"
     CDS             49323..49823
                     /gene="rpsE"
                     /locus_tag="SCH06_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEG1076932.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            49838..50017
                     /gene="rpmD"
                     /locus_tag="SCH06_000327"
     CDS             49838..50017
                     /gene="rpmD"
                     /locus_tag="SCH06_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEG1076933.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            50061..50501
                     /gene="rplO"
                     /locus_tag="SCH06_000328"
     CDS             50061..50501
                     /gene="rplO"
                     /locus_tag="SCH06_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEG1076934.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            50501..51796
                     /gene="secY"
                     /locus_tag="SCH06_000329"
     CDS             50501..51796
                     /gene="secY"
                     /locus_tag="SCH06_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEG1076935.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            51858..52505
                     /locus_tag="SCH06_000330"
     CDS             51858..52505
                     /locus_tag="SCH06_000330"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEG1076936.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            52696..52914
                     /gene="infA"
                     /locus_tag="SCH06_000331"
     CDS             52696..52914
                     /gene="infA"
                     /locus_tag="SCH06_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEG1076937.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            52947..53063
                     /gene="rpmJ"
                     /locus_tag="SCH06_000332"
     CDS             52947..53063
                     /gene="rpmJ"
                     /locus_tag="SCH06_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEG1076938.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            53081..53446
                     /gene="rpsM"
                     /locus_tag="SCH06_000333"
     CDS             53081..53446
                     /gene="rpsM"
                     /locus_tag="SCH06_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEG1076939.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            53474..53863
                     /gene="rpsK"
                     /locus_tag="SCH06_000334"
     CDS             53474..53863
                     /gene="rpsK"
                     /locus_tag="SCH06_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEG1076940.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            53943..54881
                     /locus_tag="SCH06_000335"
     CDS             53943..54881
                     /locus_tag="SCH06_000335"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEG1076941.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            54909..55289
                     /gene="rplQ"
                     /locus_tag="SCH06_000336"
     CDS             54909..55289
                     /gene="rplQ"
                     /locus_tag="SCH06_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEG1076942.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            55561..56400
                     /locus_tag="SCH06_000337"
     CDS             55561..56400
                     /locus_tag="SCH06_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEG1076943.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            56376..57245
                     /locus_tag="SCH06_000338"
     CDS             56376..57245
                     /locus_tag="SCH06_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEG1076944.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            57235..58032
                     /locus_tag="SCH06_000339"
     CDS             57235..58032
                     /locus_tag="SCH06_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEG1076945.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            58235..58981
                     /gene="truA"
                     /locus_tag="SCH06_000340"
     CDS             58235..58981
                     /gene="truA"
                     /locus_tag="SCH06_000340"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEG1076946.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(59314..61983)
                     /locus_tag="SCH06_000341"
     CDS             complement(59314..61983)
                     /locus_tag="SCH06_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEG1076947.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(62221..62409)
                     /locus_tag="SCH06_000342"
     CDS             complement(62221..62409)
                     /locus_tag="SCH06_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEG1076948.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            62679..63041
                     /locus_tag="SCH06_000343"
     CDS             62679..63041
                     /locus_tag="SCH06_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEG1076949.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            63093..64775
                     /locus_tag="SCH06_000344"
     CDS             63093..64775
                     /locus_tag="SCH06_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEG1076950.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            64892..66928
                     /gene="recG"
                     /locus_tag="SCH06_000345"
     CDS             64892..66928
                     /gene="recG"
                     /locus_tag="SCH06_000345"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEG1076951.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            66977..67978
                     /gene="plsX"
                     /locus_tag="SCH06_000346"
     CDS             66977..67978
                     /gene="plsX"
                     /locus_tag="SCH06_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEG1076952.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            68100..68342
                     /gene="acpP"
                     /locus_tag="SCH06_000347"
     CDS             68100..68342
                     /gene="acpP"
                     /locus_tag="SCH06_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEG1076953.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT        22456 a        12230 c        14404 g        19346 t
ORIGIN      
        1 atctctttta attaaaacat tagaaagaaa gagctcttca aattattatg aaggaggtaa
       61 cgagattgtt tctaaaatga aaatatcaga ggtaacttta gatgagactg acgattttac
      121 ttattataaa ggatataaaa agggctggaa tacgctttgc acatatctta aaataagagt
      181 tccttttgat gatttagact tttttgaaag tcataaagat ttgattaccc agacagcaag
      241 ctccatatat gataaacaag gtgataatgt attagtggat actattttag taccacttcc
      301 agagaattac gaagtaatta actttagtca gttgaaaatt agtgatgtgg tttcacaagc
      361 tattgaagac gctgagtctt ttatgagtaa tggtgaatat caacgtgcct ttgacagagt
      421 tcacactgct tttcatggat atttaattga aatactaaaa aaatatgaaa ttacagttcc
      481 tagagacgaa aatctatcta aattatatag taggatacaa caattaattg aaaaagaaat
      541 tcaacctact gaacttgctg atatagtgaa gacaacgata aggtcatcaa atggaatgat
      601 tagctctctt aatgaagcaa gaaataggca ttcacttgca caccctaata caaatattat
      661 tggaaagaga gaagcaaaac taataatagg tatttcaagt acagttacag attatattag
      721 cggatacctt gataagtagc gtcattaact gattgctact ttttttatga ctatttttat
      781 aaaaaggatg tgataagaat tggaaatgaa agtctatgtg gcaaatttag gacggtataa
      841 tgaaggtgaa ttagtcggag catggtttac tccaccaatt gatgaggaag aaatggcaga
      901 aagaatcggt ttaaatgagg actacgaaga atatgcaata catgattttg agcttccttt
      961 tgatgtggac gaatacacgc cgattagtga aatcaaccgt ctatgtgaag ccattcaaga
     1021 aatcgaaggt acacctattt ataatgaact caaagaaatt caaggcatgt ggtttagtag
     1081 cttggaagaa ttactggaaa acaaagagga tattcattgt tatagtgatt gtgattcgat
     1141 ggaagatgtc gcccgttatt acgtggaaga aacaggacag cttggtgaag tcccttccaa
     1201 tttacaaaat tatattgact accaatcttt gggacgtgat atggaaatag agggtaatta
     1261 cctagttacc tctcatgggg tatttgaata ttgtcagtaa gtttaacaat ccgtgttata
     1321 attaaattaa taaatagcac ggagaggtat aaattatggt aaatgtattt gaaaatctta
     1381 aactattaaa actagacatg aaagataaag gctgggtgat agattccttt tactttcgtt
     1441 acaaacagca aaattatatt gtacttgtta agctatttga aaaagaggaa aaagttccag
     1501 aatatgctct gttaaaacta gaatttttaa aggaaaacga tttttcagat atgctagctg
     1561 tctatgctaa ttcggtaaaa ttatatacag acacgaaaac aataagagaa tattttggta
     1621 tcgaatacag tagtaacttg ggagatgttt tatttcaatt tagccaaact cttgctcgat
     1681 ttattccgac agaagttagt gagaagaaaa atgaagacca aaaagaagcc atgtgtttct
     1741 cattaagtca aagtgattca gaagatccca gaaaaaaata ttgtttttca gttagaagaa
     1801 atcctttaaa gggaaatggt gagctgggaa aacgaagtcc ttttaatgac aataaaacga
     1861 gattgtatag acccagctta tatgaacgat tagggtcaga taccaattta agtttcagat
     1921 attcaatgaa tccagatgat gaagaaactg atgaaggtat tattgcaaaa tggacaaaaa
     1981 ataaaattga atagttaaag cattgaaaga gcaatcacct attttgattg ttctttttct
     2041 atttttacgg aaaggacgtg aagacatgaa aaaaataaga agttacacca gtatttggtc
     2101 agtagaaaaa gtgatttatg cgattaatga tttacaactc cctttcccaa ttacctttac
     2161 gcaaatgaca tggtttatcg tttctttgtt tgtcgtcata ctctttggca gtttaccacc
     2221 actttctctg attgacggag cactactcaa atacttaggg attcccattg ttctcactgg
     2281 gttcatgtgc caaaagacct ttgacggaaa gaaaccctat ggatttctaa agtctatcat
     2341 tacctatgct ctacgcccta aagtaaccta cgctggcaaa caaatacgat taaaaaaaga
     2401 aacaatgaat gaatcgatta cgattgtaag gagtgaacaa ctagatggca tatccgatta
     2461 aatatatgga agataatctc gtatttaatc atgatggcga agtattcgct tattatgaat
     2521 taattcccta taattacagt tttttaagtt ccgatgaaaa aattcaagtt catgataatt
     2581 tctgtcaatt gattgcccaa aatcgtgatg gcaagattca tgctctgcaa ctagcaaccg
     2641 aatcaagtat tcgagccaca caggaacaat cgaaaaaaga aatcactgga cgattaaaag
     2701 agatagctta cgaaaaaata gatgaacaga ccgaagcgtt aatttctatg attggtgaca
     2761 atcaagtaga ctatcgcttt tttattggtt ttaaactcta cctcaatgaa caggaagtat
     2821 ccgtaaaaaa tgttgggaaa gaaattcaaa aagcatttgc ggaattcttt catggtgtga
     2881 atcacaaatt aatgggcgat tttgtttcta tgcctatggc ggaaatcgaa cgcttttcta
     2941 agatggaaca gttgttagaa agtaaattat ccagacgctt tcagattcgt aaattggaga
     3001 aagatgattt tggttatatt attgaacatc tttacgggca aacaggtgtc ccttttgatg
     3061 actacgacta ccatttaccg aaacgatacg aagataaaaa agtgttggta aagaaatacg
     3121 atattctcaa acccactcgc tgtttaatcg aagaaaatca acgctattta cggattgaac
     3181 aggaagatac cactacttat gtggcgtatt ttacaattaa tagtattgtt ggtgaattgg
     3241 atttccctaa tagtgaaatt ttttattacc agcaacagca gtttactttc cccgttgata
     3301 ccagtatgaa tgttgaaatt gtcgccaata aaaaagcctt atctaccgtt cgcaataaaa
     3361 agaaagaact gaaagattta gatagccacg catgggaaag cgacaacgaa accagtacta
     3421 atgtggtgga cgctttagaa tctgtcgatg aattagaaag taatttagac caaaccaaag
     3481 aatctatgta caaactaagc tatgtggtac gggtatcagc aaagaatttg gacgagctga
     3541 aacaacgttg tgatgaagta aaagattttt atgatgatct gtctatcaaa ttagtacgac
     3601 cttttggcga tatgctaggc ttgcataatg aatttattcc ctcaagcaag cgatatatca
     3661 atgactatat tcaatatgtc acgtcggatt ttttggctgg tcttggtttc ggtgctacac
     3721 aaatgattgg tgaaaattct ggtatttacg tcggttacaa tctcgataca ggcagaaata
     3781 tttatctcca acctagcctt gcaagtcaag gaattaaagg ctctgtaaca aatgcattag
     3841 cgtccgcttt tattggttca ttaggtggcg gaaaatcatt ctctaacaat atgctggtct
     3901 attattcagt actctttggc ggacaggcaa ccattgttga cccaaaagct gaacgtggtg
     3961 aatggaaaga aaccttacct gatattgccc atgaaatcaa tattgttaat ctcacgagtg
     4021 agaacgacaa taaagggtta cttgaccctt atgtgatttt aaaactcccg aaagattcag
     4081 aaagccttgc cattgatatt ctcacgttct taacaggtat ttccagccga gatagcgaga
     4141 agtttcctgt cctgcgtaaa gctattcgga gtgtaactca aagcaaacaa cgagggttgt
     4201 tattggtgat tgatgaattg cgaaaagaag atacgcccat cagcaatagt attgctgacc
     4261 atatcgaaag ctttgtcgat tatgattttg cccatctgtt attcagtgat ggcagtgtca
     4321 cccaatccat tagcttggaa aaacaactca atattattca agtggcagat ttggtcttac
     4381 ccgattccaa tagctctttt gaagaataca ctaccatgga attattaagt gtggcaatgc
     4441 tgattgtcat tagtaccttt gctttagact ttatccactc tgaccgttcc atttttaaaa
     4501 ttgttgacct tgatgaggct tggagttttt tacaagtggc acaaggaaaa gctctatcta
     4561 tgcgattggt tcgagcagga cgtgccatga atgcaggggt ctatttcgtt actcaaaacg
     4621 cggacgattt actagatgaa aagatgaaga ataatattgg cttgaaattt gcctttcgtt
     4681 ccactgacct agtggaaatc aaaaagacct tagaattttt tggtgtggac aaggaagatg
     4741 aaaacaatca gaaacgctta cgtgaattag aaaatggaca atgtttagtt tcagacatct
     4801 atggtcgtgt aggggttatg cagtttcacc cgatttttga agagttgctt catgcctttg
     4861 ataccagacc gcctgtgcga aatgaggtgg aagaatgaca caaaaacaaa agaaatttct
     4921 tcactatagt tggataacgc tcctttgtgt gggcgttatt ttacttttat taggcacgct
     4981 gggcaatgca gtacaagcga caggcttagt tgatgaaacc attgatacaa gcaatgaata
     5041 ctccaagtat ggtttgaatc aatatcagct tgattattat gtggacaata gctggggctg
     5101 gcttccatgg aattggagtg atggcatagg acaatcggtg atgtatggat tgtatgccat
     5161 tactaatttt atttggacaa tttctcttta tctatcgaac gccacaggtt atttggtgaa
     5221 agaagcctat gccttagatt tcattagtca aacatcccaa gcaattggcg aaaacatgca
     5281 gacgattgca ggcattacac cgaatggctt ttccagttca gggttttatg tcggtttcct
     5341 ccttcttttt attctcattg ttggaatcta tgttgcctat acaggattgg ttaagcgaga
     5401 aacgacgaaa gtgatacgag ctgttttaaa ctttgtcgtg gtgtttattc tatcggcttc
     5461 ctttattgcg tatgcacccg attatattgc gaaaatcaat gatttttcca aagatgtcag
     5521 taccgccagt ctgaatattg ggacaaaaat tgttcttcct aacacggata gtcaagggaa
     5581 agacagtgtg gacatgatac gtgacagctt attctctgtt caagtaaagc aaccatggct
     5641 attgcttcaa tatggctcca ctgatgtaga agcgttaggg gaagaacgtg tggaaagttt
     5701 attgtctacc agtccagata caaacaatgg tgaagataga gaaaatgtag tgattgaaga
     5761 aattgaagat catgacaata cctatttaac cctaccgaag acgatttcca gattaggaac
     5821 agtcttcttt ttgtttgtat tcaatattgg tatctcgatt tttgttttcc ttctaacagg
     5881 aatcatgatt ttttcgcaag tgctatttat tattttcgct atgtttttgc caatcagttt
     5941 cctattaagt atgttgccga gttttgatgg catgggcagg catgccatta ccaagttatt
     6001 taatgtgatt atgacaaggg ctggtattac cttgattatt accgttgcct ttagtatttc
     6061 cactatgctt tattcgctgt cagcaagttc tccctttttc atgattatgt ttttacaaat
     6121 tgtgaccttt gcagggattt attttaaact gggcgattta atgagcctat tcactttaca
     6181 aagcaacgac tctcaaaaca tgggcagaca agtgtttcgc agacctcgtc aaatgatgaa
     6241 tcgacaaacc agaagatttc aacgcagtat gagtaagatt tttcgtggaa aagcagggtc
     6301 aacgaagcaa aagacaatga caacaaagca gaatcaaacc aataaagcta accatactcg
     6361 tcaaaatgaa cggactacac caaagaaaga aacagcactt tccaatgtga aaaagcaaca
     6421 aggcggtatc gggcaacgat taggtgaaaa gacagcccat gtattggaca cgaaaaatcg
     6481 tctagtcaat aaaagaaagc aggcaaaaca acagatacag gcgacaccaa cccatgtcaa
     6541 atatgccctt catcaaggaa aagagaatgt cactcataat gtaacagact ttaaacaatc
     6601 tatggcagat accaaagctc aacgcaaaca acagcgtatg aaccagcagg agcaaaaacg
     6661 aaagaacatt gctcaaaagc gtttggagct ggataaagca aaagaaaaaa gacgaaaaga
     6721 aaacccatca tctcctgttc agaataacca gcagcatgtt cgcaagcgtc agcaaaccgt
     6781 cacgcctgtt ttgtcacaaa acactaaacg tgaaaatcat cagcgaccat tgaaaaaaga
     6841 gcaaaaacaa aagacaccac cgaagcaatt caatcagagg aagctaaata aaagaacgga
     6901 taagcgagga caacaaacat gaagctaaaa ataacagtga tttgtagtgt ggtcttctct
     6961 ctcttctttt ttctcttatt attcctagtc attttctttg cagatgatac ggacagtggc
     7021 gaaaacaaca aggattcttc tattccacaa ggcggtgtga ccgtttcacc agaagtgttg
     7081 gcacaccgtc cgttgattga aaaatatggt aaggaatatg ggattgaaga ctatgtttct
     7141 tatatcttag ccattatgca agtggaatcg ggcggtacag cagaagatgt tatgcaaagt
     7201 tccgaatctt tgggtttacc gcccaacagt ttgagtaccg aagagtccat caaacaaggg
     7261 gttaaatatt tcagtgaatt attaaccagt gcagaacaac aaggagtgga tatagattct
     7321 gttatccaat cttataatta tggcggtggc tttttaaatt atgtgaggag tcatgggaaa
     7381 aaatatacct atgaattagc cgaacagttt tctaaagaga agtcgggtgg tcaaaaagca
     7441 gactatccca atcctatagc catacctgtg aatggtggtt ggcgatataa ctatggaaat
     7501 cagttttatg ttcagttggt ttcacaatac ctaaccgaca cttccccaac agaatttgat
     7561 gatgaaaccg tgcaagtcat tatggacgaa gccttgaaat acgaagggtt tccctatgtc
     7621 tttggagggg cgtcgcctac cacctctttt gattgtagtg gcttaataca atgggtgtat
     7681 gacaaagctg gcatttctct ccctcgtgtc gcccaagatc agtatgacgc tacgcaagaa
     7741 atctctatgg aagaagccca agcaggcgac cttatcttct ttcattcaac ctataatgca
     7801 ggcacatatg tgactcatgt ggcgatatat ttagagggaa atcgctttta tcatgcaggc
     7861 gacccaatcg gttatggcga cttaagcagt cgttattggc aagaccatct gattggggct
     7921 agacgtgtta ttcataacta agaaaggaat gaatcaaatg attataaaaa tcgagcgaaa
     7981 agaaaagaag gagaaaccaa agaaatctaa aaaaccgagc aagcaaagaa aagttccgat
     8041 gattaaagtt ggcacgcata agaaattaac ctttgtttta tgggttttat tgattggtag
     8101 tgtcggattt ggaatctata aaaattttac tgccattgac actcatactg tccgtgaaac
     8161 agaaatcatt aaacagcaga ttgtcgatac caaccaagta gaaagttttg tgaaatcctt
     8221 tgcgaaagac tacttttcgt ggcaacaatc ccaagaagcc attgataaac gaaatgaaaa
     8281 attgacccat tatttgacgg aagaattgca ggtattaaat gaagaaatga ttcgtaagga
     8341 tattcctact agttctagtg tgaacgatat acaggtgtgg caggtttctc aagtgaatga
     8401 gaacaccttt gaggtactgt tttctgttga acaagttatt accgaagaca aagacaagga
     8461 aactatatcg tctagctttc atgtggttgt ccatatagat gaatcagata atatggttat
     8521 tatcaaaaat ccgacaatga gtaagaaacc tcaaaaatcg gactaccaac ccaaacagct
     8581 agaaagtgac catacagtag atacagaaac gatggacgaa atcactagct ttttagaaac
     8641 gttcttccag ctctatccta ccgccacaga aaaagaattg acttactatg taagtaatca
     8701 tgtgttacct atgattaaca aggaatatgt tttcgaggaa ttggtgaatc ctatctttac
     8761 cagaaaagat aaccaagtaa tcgtgaatgt cgctgtgaaa tatttagatc aagaaacaaa
     8821 ggcaacccaa atctcgcaat ttgagttgat attagaaaaa caagataatt ggaagattgt
     8881 aaaataacaa atattggtac atgattacag atactttgta atcatgtact ctttttgata
     8941 aaaaattgga gattccttta caaatatgct cttacgtgct attatttaag tgactattta
     9001 aaaggagtta ataaatatgc ggcaaggtat tcttaaataa actgtcaatt tgatagcggg
     9061 aacaaataat tagatgtcct tttttaggag ggcttagttt tttgtaccca gtttaagaat
     9121 acctttatca tgtgattcta aagtatccag agaatatctg tatgctttgt atacctatgg
     9181 ttatgcataa aaatcccagt gataaaagta tttatcactg ggatttttat gcccttttgg
     9241 gtttttgaat ggaggaaaat cacatgaaaa ttattaatat tggagtttta gctcatgttg
     9301 atgcaggaaa aactacctta acagaaagct tattatataa cagtggagcg attacagaat
     9361 taggaagcgt ggacaaaggt acaacgagga cggataatac gcttttagaa cgtcagagag
     9421 gaattacaat tcagacagga ataacctctt ttcagtggga aaatacgaag gtgaacatca
     9481 tagacacgcc aggacatatg gatttcttag cagaagtata tcgttcatta tcagttttag
     9541 atggggcaat tctactgatt tctgcaaaag atggcgtaca agcacaaact cgtatattat
     9601 ttcatgcact taggaaaatg gggattccca caatcttttt tatcaataag attgaccaaa
     9661 atggaattga tttatcaacg gtttatcagg atattaaaga gaaactttct gccgaaattg
     9721 taatcaaaca gaaggtagaa ctgtatccta atatgtgtgt gacgaacttt accgaatctg
     9781 aacaatggga tacggtaata gagggaaacg atgacctttt agagaaatat atgtccggta
     9841 aatcattaga agcattggaa ctcgaacaag aggaaagcat aagatttcag aattgttctc
     9901 tgttccctct ttatcatgga agtgcaaaaa gtaatatagg gattgataac cttatagaag
     9961 ttattactaa taaattttat tcatcaacac atcgaggtcc gtctgaactt tgcggaaatg
    10021 ttttcaaaat tgaatataca aaaaaaagac aacgtcttgc atattaagta gttcagtttt
    10081 ggagtacaaa aagtgaaaat gtaaacctaa atgagtatca aattgcaact gaatttgata
    10141 ctcgtttttt attgttaaat caacgtttgt tgttaattta caccacaaaa tgtaagttaa
    10201 aatgtatata aaaatgcgaa cgtgaaataa ttattgtagg aatgcaaatt ggtgtgttaa
    10261 aatggttaca atttactaag caaaaagggg tgcattttcc tatgcaattt cttgagccaa
    10321 aaaataagaa cgctaagtct gtggattggg aaatatcaga gcaagtaagg gtgatagtta
    10381 agcaatacgc tgaatatgca gagcgtactg aaagcgaagc agtggatgaa ttcttattga
    10441 acattttaga cgataagaag tttattgaat ggattgccaa caagcgaagt aataagcgga
    10501 ttgttgaaaa aatgggtatc aaagatagag tgggttgata gacaatgacc aagcttaaaa
    10561 gattagccac gaaggaagat gaaattgtag atgttaaaat tccgatttca aacgaagaat
    10621 taaaagatag ggctaaacaa tatgatttat taactccaaa acgatttgca acaaggtata
    10681 acaaaatgtt gttcttgcca acgtctttta aatggaacgg ttctgaatat cccattcaat
    10741 ataattactg catcaatccg ttttgttgta attttgggaa agaacagcac aaattcaaag
    10801 atgtaaaagg gaaaccaagt cgatataaaa tgactggtag ttccaaagat aaaggtcata
    10861 aaggtatgta ctgcaatgac aatcctattg gcagaggtgt atcgcaaaac tgtacagtaa
    10921 cccctttatc taattggtct gttgttgaag aaattaaacg ccttatagaa atcaatagca
    10981 tccaagatgt tgagccagat tatcaatttc ataaagaagg ctgctcggaa gaagaatcaa
    11041 ccccattcaa tgagccgaag caattttaca aaagggggaa aagtaggggc aaatctcaac
    11101 gctatcaatg taaggcgtgt aagaagttca ctaatgttct accaaaaaga gaagaaacca
    11161 ctacttatca ccaacaaaag aacaccattc ttccaatgtt cgctaagatg gttgttggaa
    11221 gggtttcagt cagtcgtact tgtgatattt taggaattgg agttggaacc tactatcata
    11281 agctggagtg gctgtatagg cgttgtttgg agtttttaga acgatatgag acacaacccc
    11341 ttcaaacaaa gaaatttaac gagatgtggc ttaatacgga caagatgcac tactacctaa
    11401 ataacgtccg taagaaagga caaggttcaa agaaatatac ggggtttgaa gaccttaata
    11461 tgcaaacgta tatagttgta tctgctgagg tcttatcaag atatgtgttc cgttctgatg
    11521 ttgcctatga ttggaatatt tcaatggatg aattaaatga agatacaaga aaattcaaag
    11581 aagaccatct caatactttt agtcgtaaaa atgataggtt agattggtct tattatccac
    11641 aagaaccatc cgctaacgat agcgaaaata ggaatgctta tcttcacgaa ttagggaaaa
    11701 ttactaatag gagtagattt gtcgatggtt taaatgttga tgctccttat actacaactg
    11761 ctcactattg gttaattaaa caaatggtta atgccgacga atggcgaatg attagtgatg
    11821 atgacttctc tattagaaac gccttttata gagtattcac gaaagaatta aggttgagcg
    11881 atgcacatca ttttatttgc caagttaaca agacgaaaag cagaaaacaa tgcttaaaag
    11941 aattcggaca agcaaaagca gaactgctcg attggggaga tatcagagga ttcaaaacaa
    12001 agtttctacg gactttggca tctcattatc taactgaatt actaacaagt catcaattcc
    12061 acgaagaggc tattagtaaa gatggagaaa gatatcgcaa atatgccgat aaccctatca
    12121 aacatccatt agccactaag gataaaggat tttattcagt tgattgtaga acggatttat
    12181 ctgctctgga accaaacgaa atcgcaaaga tgctattaaa tgttaatgac cattcgacca
    12241 atagctttat tcaacagata agacgttata tatcatctct tgaaagacca ttaacaacag
    12301 ctcgtggtga taagaagagc tatatttacg ctaacttcaa tccgaagtat gctcaatttg
    12361 cgattacaat tctaagaact tactacaact tttgtcgccc ttttaaatca gcggataaaa
    12421 aggttttgac acctgctcaa agattaggga ttacagataa acaatttgat tggaaagata
    12481 taatttattt caaatgacaa aaagagcttg gagtaatccc aagctcttgt gctttatctt
    12541 tactgttctt cttcaattaa cgcacccgtt aactcaataa gttttttctt tcatatacat
    12601 gaaaatagta gttatacgga tttttatcat tctttatccc tttttgggca aatacctcat
    12661 tccattcctc ataattcact tctggaaaaa aagtatctcc ttcgaattca tgatgtattt
    12721 ttgtgatgta cattttctca acataaggga aaaacaaatt ataaatctgt tctcctccga
    12781 aaataaaaat ttcttcttcg tttttacata actcaaaaac atcttctatt gaatgaacaa
    12841 tttcacaacc attaaaggta aaccccttat ctctcgtcag aataatattt cttctgtcag
    12901 gtaaggctct tccgattgat tcaaggttct tcctacctaa tattatcgga tgtccctttg
    12961 tagtattttt aacatattcc cagtccttgg gaatcctcca aggaatgtca ttctctttgc
    13021 caatcactct attcttatcc atcgcagcaa tcaaagaaac tttcatttat aacacagcct
    13081 ttttaactaa tttaccatct aatttcttat ttctatcaaa aaaccttttc tcattatcct
    13141 gcccgttagt tgaataagca attttttcta taagttatat tatcataata ccacaaaatc
    13201 acaaattttc attcaattat cattttcaat tgcattttat aaatcatttt gtatgtaatt
    13261 tggtatgtaa gttaaaatga aaaaagtagt ccattttgaa gtacattttg tcattttgta
    13321 ctccaaaact gaactactta cttgcatata tacgccttta tagtggagta ctacatttac
    13381 gagattcggt tagagtatca gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa
    13441 taaatggtga attatgtaag attgatagag cttattctgg agaaattgtt attttgcaaa
    13501 atgagttttt gaagttaaat agtgttcttg gagatacaaa actattgcca cagagaaaaa
    13561 agattgaaaa tccgcaccct ctactacaaa caactgttga accgagtaaa cctgaacaga
    13621 gagaaatgtt gcttgatgcc cttttggaaa tctcagatag tgatccgctt ctacgatatt
    13681 acgtggattc tacgacacat gaaattatac tttctttctt agggaaagta caaatggaag
    13741 tgattagtgc actgttgcaa gaaaagtatc atgtggagat agaactaaaa gagcctacag
    13801 tcatttatat ggagagaccg ttaaaaaatg cagaatatac cattcacatc gaagtgccgc
    13861 caaatccttt ctgggcttcc attggtttat ctgtatcacc gcttccgttg ggaagtggaa
    13921 tgcagtatga gagctcggtt tctcttggat acttaaatca atcatttcaa aatgcagtta
    13981 tggaagggat acgctatggt tgcgaacaag gattatatgg ttggaatgtg acggattgta
    14041 aaatctgttt taagtacggt ttatactata gccctgttag tactccagca gattttcgga
    14101 tgcttactcc tattgtactg gagcaagcct ttagaaaagc tggaacagaa ttgttagagc
    14161 catatcttag ttttaaagtt tatgcaccac aggaatatct ttcacgggca tataacgatg
    14221 ctcccaaata ttgtgcaaat atcgtaaata ctcaactgaa aaataatgag gtcattatta
    14281 ttggagaaat tcctgctcga tgtattcaag attatcgcaa tgatttaact ttttttacaa
    14341 atgggcttag tgtttgttta gcagagctaa aaggatatca ggttaccact ggcgaacctg
    14401 tttgccagac ccgtcgtcta aatagtcgga tagataaagt aagatatatg ttcaataaaa
    14461 taacttagtg cgttttatgt tgttatataa atatggtttc ttattaaata agatgaaata
    14521 ttctttaata tagatttgaa ttaaagtgga aaggaggaga ttgttattat aaactacaag
    14581 tggatattgt gtcctatttg tggaaataaa acaagactac gaatacgagt ggatactata
    14641 cttaaaaatt tccctttata ctgccccaaa tgtaagaacg aaactttaat taatgttcaa
    14701 aaaatgaata taataacaat caaagagcca gacgccaaga cgcagagccg ataatttgag
    14761 aaatgaaact ctcatcttat cggctctttt tgtttatctg aattttactg actagccttc
    14821 aatatttctt gcttcattga taccttttgc tagtgcttcc attaaggata gttctttgtc
    14881 tgtaaagcta tccatgtatt tttctacctg taaccttcga gtgcttttaa tcaaattatc
    14941 tgtaggtaag aaaaattcat caatagatac atggagtaat gatacaagat catacagcac
    15001 ttgtgtactt gggtgttgtc ctttgttttc tatatttgtt aaataacgtg ggtcaatttc
    15061 aatcattgtt cccacttgtt cacgagtgag accccgtttc attcgagcct ctttaatcgc
    15121 taaaccaacg gctctaaaat cgtatttatc ttctttttta cgcatactaa atcacctcta
    15181 tacattttac tgttcctata taaccataaa caggtataga aaaacatgtt atatagttta
    15241 tgagttccta tagaacactg tggaatttat taatgcgatg aatccaattt caaatagaaa
    15301 ggtcgctgat tttatttacc tatacaactt tataaaattt agtcatactc ctagaaagta
    15361 gataaaattg gcgacttaat ggagggaaaa gtcgccatga gaaagataat ctgtcatcta
    15421 gttctcttaa ttaagttctt atcaaaaaaa cttatccacc tgtactggat agatatgacc
    15481 atcaatgtgg ttttgcagat tacatagata gaaaaatcaa agcatatgaa cagagaaaac
    15541 aatctgttta tgtgcttttt tggtcactta ataaatatct tttaggattt ctcttcattt
    15601 atgcaacaaa tcccccgttc gtgtcggggt ttagtatgaa gggagataaa gaagcacatg
    15661 ccactccctt tcacgacaga aagggggtga aaagcatgaa accatcttct tttcaagaaa
    15721 ccatagaaaa tcagtttgac tatatctgca aacaagttat tgaagatgaa cgaaaagatt
    15781 acttcaaaca tctagacaga ctatcagcaa aagaagtctc gttttctgat atagataact
    15841 accttgtcaa ctctttttct actgttgata cgtacgtcac tgatttccaa ctatttaaat
    15901 tatttggatt aagaatcaat gttgaaagtg atttattaag tgaagccctg cgtcatcttt
    15961 cagagaaaaa acggaacatt attttacttc attactttat ggatatgagt gatgtggaga
    16021 ttgcggagtt actaaatttg aatcgttcga ctgtttatcg tcatcgaata agtggactag
    16081 ccatgattaa agaattcatg aaggagtgta aagaatgaaa acagcttatc caagggttcc
    16141 cttccccctc attgtaaagg cgacagatgg cgacgtggaa gcaattaatc agattgttaa
    16201 acattatcga gggtatacct caaaacgttc attacgtcgc atgacagacg aatatggaaa
    16261 ttctcatatg gttattgatg aaaccctacg tggcagaatg gaaacgaaac tcatctctaa
    16321 gattttatcg ttcgaaatta aatagtccca ttttttcgtg gaagcgtgtc gaatcgtatc
    16381 cacgcttccc gatttgggag gtttgttatt ccatcaaagc atattgtgtg ttcagtaggt
    16441 tttgataggc taacaagcca aacgttcttt gacaaccaaa taaaggcaat cgaatacgtt
    16501 tcggtaagaa aagagctgat gaactaacac gccatgacct acaaaattag tgagcgattc
    16561 atgttagtaa ttcgaaagta atctttagca ggattgctgc catgactttc ttatcgtgat
    16621 aatgatactc ccgtatagcc atagtccgag cgttagaagc gtcacaggca atgggtacgg
    16681 ctacatgaga accatgcaga agtgaaattc ctgtgagctt tgctagagct gttcgattgc
    16741 taagatattc ttctcttgtc agtgtattat tataaaacta tttgatataa ttataggtga
    16801 atattggagt tttcctagcc tataattggg aaaggagtaa taatgataac ggtcacaaaa
    16861 aaggatttag ttgagctagg atatggaact tctttttcag cagacatcat aaaaaaagca
    16921 aaagaattga tgattacaaa agggcatatc tactatcaat ctcgaaagct agatagagtc
    16981 cctcgtgaag ctgttgaaga aattctagga attcggtttt caaatgaaaa caggtctgag
    17041 tagtttttgc acagtaagga gtaaaaacta tggttaaaga cccaataaaa aaagcaaaga
    17101 atggaaccta ttattttcgt gcaaatctag gttatgattc taaagggaaa aaaattcaaa
    17161 aatatcgtag tggattcact actaaaaaag aagcaagaga agaatattcg aaactgctat
    17221 tgatgaaacc agaagaatta agtgagaata aggataaaat gacgtttaaa cattatatct
    17281 ttgaaatttt ccttccatgg tataagacac aggtaaagct cagaacatat gaaaatcgct
    17341 taccaactat taagaagcat ttctcttatt ttgataaaat ggctgtttcc gatattgagc
    17401 ctattgatgt gcaaaattgg caactaaaat tatcaaagaa gtgtaagtct tcttatgtaa
    17461 gagctgttca aggactattt tcagttgcta tggatcgagc aattgtcctt gggataacca
    17521 ccacaaatcc atctaagatt attggcaatg tgaaaaagca aaagtctaaa attgaatttt
    17581 ggacaaaaga agaatttgaa aaagtaatct ctctaattta caaagaagat tactatcaac
    17641 actttttatt tatctctctg tggtttttat ttatgactgg aatgcgaatt ggtgaagcta
    17701 ctgccattca atgggaagat attgattttg actcaggagt actaaccatc aacaaaacac
    17761 tctattacaa gaatcaatcg aattatagat ttgttgaacc aaaaacaaag gcgagcgttc
    17821 gtcatattgt attagataaa tgcacattaa cttatttatc cgaatggaag gaagtacaac
    17881 aaaatctaat tcagacagac tttgtaatga gctataacgg tattcctacc caaaaacata
    17941 cactatcata tgctattgaa cgctatgcta agctggctgg tatccatcga atcagaatcc
    18001 atgggttacg gcattctcat gcttccttgt taatcagtat gggagaaaat ccacttatca
    18061 ttaaagatcg tctaggacac gaagatattg agacgacttt aggaacgtat ggacatcttt
    18121 atcctaacag taatttcgag gtagctaaca aattaaatgg agccatttcc tttaaagaag
    18181 caaaacaaaa ttatgatact tcaccaaaga atcaatttac tgtagactac ttgcgaaaca
    18241 aagaaatgaa aaaagtgcaa taaaagtgca gtaaaaagat aagaagagcc agaaaccctt
    18301 ggtataagag gatttctagc tctcctacaa ctattcccac tccactgttg ctggtggttt
    18361 agaagtgatg tcatacacga tacggttgac gtgggctact tcgtttacga tacgtacaga
    18421 gattttttgc aagacttccc atgggatacg ggcaaagtca gcggtcattc cgtcgattga
    18481 agttacagca cggataccga ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac
    18541 agagcggatc cctggaagaa cagtgaaata ttgccagata tcacggtcaa gtccagcagc
    18601 tgcgatttct tcacgcaaga tagcatcaga ttcgcgtacg atttctagct tgtcttcagt
    18661 gatttcgcca agaacacgaa taccaagacc aggaccaggg aatggctgac gccaaacgat
    18721 tgaatcaggc atgcctaact gagtccctaa ttcacggact tcgtctttga ataatgtgtt
    18781 taatggttcg atcaattcaa attgcatatc ttctggcagt ccacctacat tatggtgaga
    18841 tttgatcgtc tgtgctgttt ctgtaccaga ttcgataacg tcagtataca acgttccttg
    18901 tgctaggaaa gagacgcctt cttcaccagc aagttttgtt gcttcgtcat caaaaacata
    18961 tacgaattca ttcccaatga ttttacgttt ttgttctggg tcagatacac ctttcaactt
    19021 gtctaagaag cgatctcttg catcgacttt gatgatgttc aagccgaatt ttccgcctag
    19081 actttccatt acttgttccg cttcgccttt gcgtagcaga ccgtggtcaa caaagataga
    19141 tgtcaattgg tcaccgatcg ctttttgtaa aagaacccca acgacactag aatcaacgcc
    19201 acctgaaaga ccaagcaaga cttttttgtc accaacttgt tcacggattt tttctacttg
    19261 catatcgata aagttatcca ttgtccagtt accttcacag tgacaaacat caaaggcaaa
    19321 gtggcgcagc aattcgattc cgtattcgga atgacgtact tctgcatgga attggatacc
    19381 ataaaaatta cgtgttgtgt cttggataga agcaatcgga caatctttgc ttgttccgac
    19441 tgtttcaaag ccttcaggaa ctttagttac caagtcacca tggctcatcc atactgtttg
    19501 ttgttttggt gtttctttaa acaagacagc ttgatcgctt gttacttcta acaaggcttt
    19561 cccatattcg cggtttttag caggctctac ggaaccgcca agtttgtacg tgatcaattg
    19621 cataccatag caaatcccta atacaggaat acctaaattg aagatctcag gatcgatccc
    19681 aaatgcattc tcatcatata cactgtttgg tccgccagaa agaatgattc cctttggatt
    19741 catcgctttt acttcttctg cagtaatgcg gtggctcaat aattcggaaa agactccaag
    19801 atcacgaata cgtcttgtga tcaattggtt atactgacta ccgtagtcta atacgataat
    19861 cttttcaacg ttcgtcatat cggcaacgtt tgtcaaattt attaccccta tccctttaaa
    19921 ttttatctca aaatagtcaa actattttaa aatgctaata ttttcgcatg aaaatcgaat
    19981 cgatgatatg attttcagtt ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga
    20041 tatattcctg taaatttttc aaattcacat ttttccatac atcttttgcc attttaaagg
    20101 cttcttcacg atctccgata gcaaaacgat aataataatt ctctggattt tggaaagccg
    20161 tatccagtaa cgcaccaaaa cgatccaaat accatttttc gatcagcacg ggatcggcat
    20221 cgacatagac agaaaaatca aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt
    20281 gaagcgtatt gatcccctca acgatcaaga tatcaggctg ctggatcaat tcgtacttgt
    20341 ctggaatgat atcatacaca tcatgtgagt aaacaggtac ttttatctct tcctgaccag
    20401 attttacacg gttcaagaaa tcgatcagca tctccatatc ataactttca ggaaatcctt
    20461 tacggtccat gattccacgc tcttttaata tacgatttgg ataaagaaat ccgtcagtcg
    20521 tgatcagctg aacgtttctt cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg
    20581 ctgttgtact ttttccaacg gctacacttc cggcgatccc gataataaaa ggcggtactt
    20641 ctacgtattt atgaagaaat aaacctttac tcaagaacaa agattcaaat tctttcatat
    20701 aaagataaat cagatgagca agaggtacat agatatctcg aacatcctgc atggaaatgc
    20761 ggtcattcaa acttttgata ttatctagtt catcttgtgt caaaggtgct tgcccattac
    20821 gataaaattc tcgccattct tctcttgcca cacggtagta gttcattgga tcattcatat
    20881 tagcctcctg cgttctccca tcaatggaac tattttaaca caaaataaac gcaaacccca
    20941 ccacttaaga gagattgccg atctttttgt ataatcttta taatagaaag aaacggagtc
    21001 ttattcttga cttgcgcacg gatacataaa aggatagact gttgtcatga aagaaatgag
    21061 aaggatggaa gacatgacaa atcattacta ttctgaacgc ccagatacgg cgcacgattt
    21121 tgaacaatgg gcttttgagt taaaaggcag aacctttcaa tttgtaacag attctggtgt
    21181 attttcacgt gaaacagtgg attatggttc acgtgtcctg attgatgctt tcgattggga
    21241 agagttacct gatgaaggaa agatcttaga tgtgggatgc gggtatggac cgattgggtt
    21301 agctttggca tttgcgacac agcggtttgt tgaaatggtc gacattaatg aacgagcggt
    21361 aagtctagcg caaggaaacg caaagcgtaa ccaaatcgaa catgttgata tccatcaatc
    21421 gaatatctat gaagcagttc atgaagaaac ctatgcagct atcgtaagca atccgccgat
    21481 ccgtgctgga aaaaaagttg tacatgaaat tttgacaggc gcatatcctc ggttgaagaa
    21541 gggcggtaca ctgacaattg tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa
    21601 aatggaagaa acatttggta atgcagaaat cgtcacaaaa gataaaggat attatatcat
    21661 caaaagtgtg aaagaataac tagctgaaaa atagtggagc gacgaaagag tggaactggg
    21721 cgtgcatgta cgggtacgta tcagttcttt ttttgttgag aagtttttaa aaacaaagaa
    21781 ctattttttc ttcaaaaaga aatagtagga acagagtcgt tgttttttac gataaaataa
    21841 ataagataca gaacttgtat agaaggctgc caagtcggta gataaaggag gtttttatca
    21901 aaaaacatac tttccttttt tctctattct tttcttgggg gttttggtac actgataggg
    21961 aatttagata gaagggagcc aataggatga agctgaccat cagagatatc gcagaaatgg
    22021 caggcgtatc agtaacaact gtctcacaga ttttgaataa caaaggaagc agatttagtg
    22081 ataagacaag aaaaaaagtg ttgtcgatcg tgaatgaaca tcattataag cccgattatt
    22141 tcgcttcaaa tgtgatcaat cgacattcaa agaccatcgg aatgatcgtc cctgatgtca
    22201 ctgatttctt cttctccaaa ctgatcgaag gtgtagagag ctatttgaat cctttgggct
    22261 atgtgatcat gttatgcaat tctcgtcata gccaagaaaa tgagatcaag tatttacaag
    22321 agctttccca ccgctcagtg gacggaatct tgctggccac accaaatatt ttacctgaga
    22381 aatatgcatt agacagcggt ttttatcaaa aaatgccaat cattttaatc gatcgcggat
    22441 tgaatcgtcg ggataacgga cggcttatcg taaaggaata tgagggcgcc tatcaagctg
    22501 tttcgctgtt tattgaaaat ggccatacga agatcggcat gctgaaggaa accactggat
    22561 actatcaatt agaagaacgt ttcaacggat atcgtcatgc gctgaaagat catggcctgc
    22621 cttttaatgg gaaatttgtt gaacatggag agttgactgt ccaaggtgga tatactgcat
    22681 caaaaaaatt actcaaacat aaagatatca cggctatttt ttgcgggaat gatgccatgg
    22741 cgatcggatg ctatcaggcg atcgatgaat tgggcaaaaa aatcccagaa gatatctcag
    22801 tcataggatt cgatggatta aagctgtcag aatacatgat tccgcaattg acgacagtgc
    22861 agcagccaag ttttgatatt ggattttatg ctgcacgttt cctgatcgat acgatcgaat
    22921 ttcctcaaag aaaagttccg aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg
    22981 taaaagtatt gacaaagggc taactcggcg gtatattgct tatgtaagca tttacaaagg
    23041 ctagttagtg ctttttttat ttttagtaaa ccagtttact aaagtggttt acctttccta
    23101 aaaataatgt ataataccga atgaagacaa ggaggatcag gcaatgcgaa tggtggatct
    23161 gattgaaaaa aagagggatg gaaacgagct gtcgaaagag gaaatcgagt acatcgtcac
    23221 gaactatacg aatggaaaga ttccagatta tcaagtcagt gcattattga tggcaatttt
    23281 ttatcaagac atgacaaatg aagaaatcac gaacttaaca ttggcgattg ctaattctgg
    23341 tgatgtcatc gatttgagtt ctcttgaagg aataaaggta gataagcatt cgacaggtgg
    23401 cgttggtgac acgaccacat tgattttagc ccccctagta gctagtgtcg gagtgacagt
    23461 ggctaaaatg tctggacgcg gtctaggtta cacaggtggt acactagaca agctagaagc
    23521 aattcccgga tttcagatcg agctttcgga tgaagaattt gtacgcattg ttaatgaaag
    23581 taaagtagcg gtaattggtc aatcaggaaa cttggcaccg gcggacaaaa aattgtatgc
    23641 cttgcgtgac gtcacagcga ccgttgattc tcttccgctg attgccagtt cgattatgag
    23701 taaaaaaatc gcggcaggag cagatgcaat cgttttggat gtgaccactg gagacggtgc
    23761 tttcatgaag aacatcgaag atgcaagacg tctggcaaag accatgacga gcattgggaa
    23821 actggctaac cgagaaacag tggcggttat ctcagatatg tcagaacctc ttggcgaagc
    23881 tatcggaaat agtctagaag ttgtcgaggc aatcgaaaca ttacaaggaa atggtccaga
    23941 agatctagta gaaatgtgct acgccttagg aagccaaatg gttgttcttg ctggcaaagc
    24001 taagacaacc gatgaagcaa gaacgttgct tcaagaagct ctggaatcag gtaaagcgtt
    24061 agcaaaattc aaagaaatga tccaaaatca agggggagac ccagcgatcg tggaacatcc
    24121 agaacgaatt ttgactgcac gctacacaat ggagcttcct gctaaacaaa gcggagttgt
    24181 gtcaaaaatc gtggcaaatg aattaggaat tgctgcaatg atgctaggtg ctgggcgtaa
    24241 aaccaaagaa gaagatattg atcacgctgt tggattgaaa ctgcataaaa aaattggtga
    24301 cactgtgaca aaaggtgagt cactattgac gatctatagt aacgacgaag aaatcacttc
    24361 tgtcattgaa ttattatata aaaatattga aattggtgaa tcggcaatga agccaacgtt
    24421 gattcatgac atcatcacag aataaaggaa aaaagcggac tttaccgttt taaagaaaag
    24481 gggaaaagaa atggaactaa accgaatgat cgaccatact attttgaaag cagacgcatc
    24541 taaagaagct gtgatgcaaa ttatcgaaga agcaaaaaaa taccattttt attctgtctg
    24601 catcaatcca gcatgggttg cgctagcgaa agaacaatta caaggtgagc cagtagccgt
    24661 atgtacagta atcgggtttc ctctaggagc aaacacaccc gagacaaaag catttgaaac
    24721 aacagatgcc atcaataacg gtgcagatga agtcgatatg gtcatcaata tcggtgcttt
    24781 gaaatcaaag gatgatcaac aagtccaaaa agatatcgaa gcagttgttg aagcagcaaa
    24841 agatcgtgcg cttgtcaaag ttattattga aacatcgtta ttagatagag aagaaatcat
    24901 ccgagcttgc gaaatagcaa aagctgcagg cgctgatttt gtcaaaacat caactggttt
    24961 ctcaacaggc ggagcaaagg tagaggatgt ccgtttgatg cgtgaaactg taggaccaga
    25021 aatgggtgtc aaagcttccg gcggtatcca taacgaagaa gaagcaatgg caatgatcga
    25081 agctggtgct acaagaatcg gaacaagcgc aggagtagca atcgtatctg gttcaactgg
    25141 tgaaggctat taattttttc aaaggagaag ctcatggcag aactcaaaca agaatggatc
    25201 aacacagcta ttgaagcgtt agataaagcc tatgttcctt attcccattt tccggtaggc
    25261 gcttgtctcg taacggaatc aggcaagatt tatcaaggca tcaacattga gaatgcatca
    25321 tttggattaa cgaattgtgc cgagcgcaca gcttttttca aagcagtatc tgaaggagaa
    25381 aaaacattta cgcatctagt cgtagcgggg cacacccccg atcctatctc tccttgtggt
    25441 gcatgtcgac aagtaatggc agaattctgt tcccctgata tgccggttac gctagtagga
    25501 gacaatggtg tgacgaaggc aacgaccgtt cgtgcactgc tgccttatgc atttactgaa
    25561 aaagatctat aactcatgtt cattcagtca gctgactgtt gaaaaataaa acaattattt
    25621 taggaggctt tacagaaatg aaaaaagcaa aattatttgg tttaggtgct gtcgcactag
    25681 cagcagggtt atttttaggt gcatgcggca acaacggctc tactgattca tccggtggca
    25741 aaagctcatc agacacaaca actgcagcat tgatcacaga cacaggtggt gtagacgacc
    25801 gttcattcaa ccagtcagct tgggaaggac tagaaaaatg ggggaaagat caaggacttt
    25861 cacgaggaaa tgatggcttc caatatttcc aatcttcaaa tgaatcagat tacatcccaa
    25921 atattgacca agcattgaat gctggattca aaacgatttt tggtattggt tataaactaa
    25981 aaccagcgat ccaagaacaa gcaacaaaca atacaggtac gaactttgtt attatcgatg
    26041 atgtcatcga tggattagat aacgttgtat ctgcaacttt caaagacaac gaagcttctt
    26101 atcttgcagg tgttgcagca gcttatacga ctgaaacaaa cgtagtcggc tttatcggcg
    26161 gtgtaaaagg tgaagtaatc gatcgttttg atgctggatt caaagccggt gttgatgcag
    26221 gtgcgaaaga attaggaaaa gaaatcaaag tattgaatca atatgctggt gacttctctg
    26281 ctccagataa aggacgttca attgctcaag gtatgtatgc acaaaacgca gatatcatct
    26341 tccatgcttc aggcggtaca ggtaacggtg tattccaaga agcaaaatca ttgaacgaat
    26401 caggcgacaa aaaagtttgg gttatcggtg ttgaccgcga ccaatcagac gaaggcgaat
    26461 acacattaaa cggcgaaaag aaaaacttca cattgacatc tacactgaaa gcagttggaa
    26521 cagtagtaga agatttggca caaaaatcag cggacggtaa attccctggc ggcgaacaca
    26581 ctgtttatgg attgaaagaa gacggtgttg gtctaacaga aggacaactt tctgacgaag
    26641 cgaaaaaagc agttgatgaa gcaaaagaaa aaatcatttc aggtgacgta aaagttccag
    26701 aaactcctga agaaaactaa aaccatttct atagccttgt tagacacatg tttgacaagg
    26761 ctatggtttg attagaacaa gaattgttca tttatccaag ctgccttgtg acagtttgga
    26821 taagggaaca actccctgaa gtaatgtttg tttcaaaaga agaacgctca ctaagcgtga
    26881 atcttagtca atcgttgccc tagatagaaa tcgttaggat gtgaaaaaaa ggtggttcaa
    26941 gaaaatattg tcatagaaat gcagaatatt accaaagaat ttggaacatt caaggcaaat
    27001 gacaacatca atttacaagt aaaggcagga gaaattcatg cgttgcttgg agaaaacggt
    27061 gctggcaaat ctacattgat gaacgtgctt tccggattat tagagccgac atcagggaaa
    27121 attttgatgc gtgggaaaga agtaaagatc acaagtccga ccaaagccaa ccaattaggg
    27181 attgggatgg tccatcagca ctttatgctt gttgatgcct ttactgtaac agaaaacatc
    27241 gtgttgggaa gcgagcctag tcgcgcaggg atgcttgacc ataaaaaagc acgaaaagag
    27301 atccaaaaag tttctgaaca gtatggattg tcagtcaacc cagatgctta cgttcgtgat
    27361 atttcagttg gaatggaaca acgggtagaa attttaaaaa cactttaccg aggagcagat
    27421 gtactgattt ttgatgagcc gacagctgta ttgacccctc aagaaattga tgaattaatc
    27481 gtgatcatga aggaattagt caaagaaggc aagtcgatca ttttgattac gcataagtta
    27541 gatgaaatca aagcagtagc tgaccgctgt acagttatcc gccgtggaaa aggaatcggt
    27601 acagtcaacg ttaaagacgt aacctcacaa caattagccg atatgatggt tggaagaacg
    27661 gtttcattca aaacgatgaa aaaagaagcg aagcctcaag aagtcgtttt gtctattgaa
    27721 aatctagtgg tgaaagaaaa tcgtggatta gaagccgtga aaaacttgaa cttagaggtt
    27781 cgtgctggcg aagtacttgg tatcgctgga atcgatggaa acgggcagtc ggagttgatc
    27841 caagctttga ctggtttgcg aaaggcagaa agcggacata tcaagctaaa aggggaagac
    27901 atcactaata aaaaaccccg aaaaatcact gaacatggtg taggacacgt gccagaagac
    27961 cgtcataaat acgggttagt cctagatatg acattatctg aaaatatcgc actacaaacc
    28021 tatcatcaaa aaccttacag taaaaacggc atgctgaatt attcagtaat gaatgaacat
    28081 gccagagaat tgatcgaaga atatgatgtt cgaacaacga atgaacttgt tcccgcaaaa
    28141 gctttatcag gcggaaatca gcaaaaagca attatcgctc gtgaagtcga ccgagatcct
    28201 gatctgttga ttgttgcaaa tccaactcgt ggactggatg taggtgcgat cgaatttatt
    28261 cataaacgtc tgatcgaaca aagggacaaa tacaaagcag tgttactgat cagtttcgaa
    28321 ttagaagaaa ttttaaatgt ttcggatcgt attgctgtta tccatgaagg agaaattgtc
    28381 ggtatcgttg atccgaaaga aacatctgaa aatgaattag gtctattgat ggcgggctat
    28441 accttagaag aagcacgaaa agagttagaa aagggggctg gcgcacatga atgatcgcag
    28501 cgaaaaattc cgtaatttat tagtgcctgt actttcagtt gttttaggat tgatcttagg
    28561 cgcgatattg atggctgctt ttggttttca gcccatccaa ggttattctt ctatgctaga
    28621 tgcagccctt ggttcgcaaa gagggatagg tgaaacgtta aggcaagcaa cgccgttgat
    28681 ttttacagca ttaggttttt ctgtagctaa ctcagctggg tttttcaata ttgggctttc
    28741 tggacaagca ctttgcgggt ggatcgtcag tgtctgggtg gcacttgcgt ttccagatct
    28801 gccaaaagtt gttttgcttc cgttatgcgt gatcttaggt gccttagctg gtgcgatggc
    28861 agcggctgtt ccaggtttac ttcgagcatt ttttggaaca agtgaagtga tcgtaacaat
    28921 catgatgaac tatatcttat tatacgtaag cacatttgct ttacatgaag tgatgcctga
    28981 aagctatcgc tcaagtttgg actcttccaa tatgatcagt caaaatgcct cactgcggtt
    29041 accatggtta acacaagctt ttggcggctc tcgcgtaaac tcaggattat ttttagcaat
    29101 catcgcgctt attttcgttt ggctgctgat gaagaaaacg actttaggat ttgaaatccg
    29161 ttctgttgga ttgaatcctt ttgcttctga gtatgcagga atgagtagta aacgtacgat
    29221 cgttttgtcg atggtcattt ctggcgcttt ggcagggctt ggcggtgtgg ttgaaggatt
    29281 aggaacgtat caaaacttct ttgttcaaac gacttcgcta tctattggat ttgacggaat
    29341 ggctgtttcc ttgcttggtt ctggatcagc aatcggtatt cttttatcag cgatcttgtt
    29401 cagtattttg aagatcggtg gacttggcat gcagacagga gcaggtgttc cgtttgagat
    29461 cgtcaatgta tcgattgctt tgattatctt ctttgtcggg atcaacttcc tgattcgttt
    29521 cgtcatggct aaagtcttcc aagggaaaaa acaagaagag atcgttgcga caatagaatc
    29581 gaaaccaacg aatcaaaacc atgaaggggg cgaactataa tgtcgactat cgaattaatt
    29641 gccttgatcc ttacttctac actggtttat tcaacaccgc taattctaac gtcactaggc
    29701 ggaacttttt ctgaacgaag cgggatcgta aacgtagggc tagagggaat catggtcatg
    29761 ggtgctttta gttccatcgt tttcaacttg acgatgagtc catcacttgg ttctatgaca
    29821 ccatggatcg ctattttagt gggtggcgtc gtaggtatcc tattttctct gattcacgca
    29881 gtagcaacag tcagtttgcg tgctgaccat attatcagcg ggacagtaat taatctgatg
    29941 gcacctgctt taggtgtttt cttgatcaaa gcatggtatg gtaaaggtca aactgataac
    30001 atcacgcaga atctggggta tttttctttc ccaggattag cagatattcc ggtcattgga
    30061 ccaattttct ttaaaaatac attcttacct gcttattgtg ctattttgat tgctgtccta
    30121 gcttgggtga tcatcttcaa gacgaaattc ggcttgcgcc tccgttcagt tggtgaaaat
    30181 cctcaagctg ccgacacatt aggtatcaat gtatatgcta tgcgttattc aggcgtactg
    30241 atttctggct tgttaggcgg tatgggcggt gctgtttttg ctcagtcgat ttccggtaac
    30301 ttttcagctg gtacgatcgt tggacaaggg ttcatctcca tggctgctat gatctttggt
    30361 aagtggaatc ctttaggggc aatgggtgcc tcattgttct ttggttttgc tcaaagcttg
    30421 agtatcattg gcgcacaatt accagttatt tcttcgattc cgccagtatt gctgcaaatt
    30481 gctccatatt tgctgacaat cattgtgctg gttgttttct tagggaaagc ttctggtcca
    30541 aaagcaaacg ggaagaacta tatcaaatca aaataatctt ttagcgaata aaaagggtgg
    30601 gttacgggaa gtgtttttcg tctcgccctt tttgttttaa aggcaataaa aataaaaaga
    30661 aagaaggaat aatcatgttt aaacgcgtac atctgatcgt catggattca gtaggaattg
    30721 gagaagcacc agatgccgat aagttcggtg atgttggttc tgatacatta ggacacattg
    30781 cgaaagaagc aggattgaac gttccacatt tagagcagct tggtttagga acgatccgtc
    30841 ctcttgaagg tgtggaatca gtgaaagatc atcaaggcta tgcgacgaaa ttagaagaag
    30901 tttctgtagg gaaagatacg atgacaggcc actgggaaat catgggattg aatatcaaaa
    30961 ctccatttcg tgtgtttcct aatggattcc ctgatgatct gatcaaacaa atcgaagaat
    31021 tttctggccg taaagtcgta tgtaacaaac cttatagcgg aacagctgtt attgacgatt
    31081 acggtgaaca ccaaatgaaa acaggcgatt taattgtata tacttctgcc gatcctgtcc
    31141 ttcagatcgc ggcacatgaa gaaatcattc ctttagaaga attatatcgg atttgccaat
    31201 tcgttcgtga tataacaaaa gatgatccgt atatgattgg ccgaatcatt gcacgtccgt
    31261 acgtgggtga accaggagac ttcacacgaa caagcaatcg ccatgattat gcgttgaatc
    31321 cattcggaca cacagtcctt gattctttga aagaagcagg aaaggacgtg attgctgttg
    31381 gaaagatcaa cgatattttc aacggacaag gaatcactga atctgtccgc acgaaaagca
    31441 atatggatgg cgttgaccag ctgctgaaag ttatgaaaaa cgatttttca ggaatcagct
    31501 ttaccaattt agtagatttt gatgcattat acggtcatcg tcgggatgta gtcggctatg
    31561 cgcatgcgat tgaagaattt gacttacgaa ttccagaatt gcttgaagcg atggaagaag
    31621 acgacttgct aatgattaca gccgatcacg gaaacgatcc gacgtttact ggtaccgatc
    31681 atacgcgaga atatgtaccg ttattggttt acagtaaaaa aatgaaagaa caaggggcat
    31741 tgcctcaagg atattattca gatatttcag caacgattgc tgagaacttt agtgtttctt
    31801 cgactgaaaa tggcgaaagc ttcttgaaat tattaaaata atctttttaa ataggagaaa
    31861 gcaaatgacc aagttaagcg agatgttaca agaaacgacc cagtttatcc ttgataaagg
    31921 agtaaaagaa attgattttg gtttgattct aggttcagga ttaggtgaat tagcagatga
    31981 aatcgaagat gctgtaatga tttcttatga tgagatcccg ttctttcctg tttcgacagt
    32041 agttgggcat gcaggaaagc tagtttatgg gtctctggca ggcaagaaag tgttagccat
    32101 gcaagggaga ttccactact atgaaggtca ttccatgcaa acagtgacct atccagtacg
    32161 tgtgatggcc ggactagggg cccattcagt cattgtgact aatgcatgtg gtggtgtcaa
    32221 cgaatcattt gtaccaggag atttgatgct gattaccgat catatcaatt ttactggtga
    32281 aaatcctttg atcggtccga atgaagatgc aatgggccct agatttccag atatgagtca
    32341 agcttatacg cctgactatc aagcaacagc aaaagcagca gcagaaaaac taggtttgga
    32401 tcttaaagaa ggcgtatata tgggctattc tggaccaact tatgaaacgc ctgcggagat
    32461 ccgaatgtct cggacaatag gagccgatgc agtagggatg tcgactgttc cagaagtcat
    32521 cgtagcagct cacagcggat taaaagtgtt aggaatctct tgtattacca acttagcagc
    32581 aggtatgcaa gcgaatctga gccatgaaga agttgtagaa acaactcaga gagtcaaaca
    32641 atcttttaaa gcattggtta aagaaacatt gacattattg taataggagg aacaataaaa
    32701 tgagtgtgca tattgaagcg aaagaaggcg agatcgccga taagatttta cttccgggag
    32761 atcctttgcg agctaaatat attgcggaga cttttttgga agatccagtt tgttacaatc
    32821 aggtacgcgg tatgttaggc tttaccggca aatataaagg agaacgtatt tctgttcaag
    32881 gaacaggaat gggaatgcca tcagccacca tctatgccca tgaattgatc cagtcgtatg
    32941 gtgtaaagaa attgattcga gtaggtacat gcggtgcatt gtcaaaagac gtccatgttc
    33001 gtgatttagt actagcacaa ggtgcagcga ccagttcttc gatgatcgaa aaaaatttcc
    33061 aagcctttca ttttcctcca atcagtgatt tcaatctatt actgaaagca tatgagatag
    33121 ctaaagaaaa gggctatacg gttcatgtag gaaatgttct ttcggaagat tctttctaca
    33181 aagatgattt gacagagacg ttccaattag ctgaacttgg cgttttagga gtggaaatgg
    33241 aagcagcggc tctttattac ttaggcgcga aataccatgt gcagacatta agtttgatga
    33301 ccgttagcga ccatttgatc accggtgaag aaacaacagc tgcagaacgt caatctacgt
    33361 tcaatgaaat gatcgaagta ggattggaaa cagcgatagc agaataagaa ggaaatgaaa
    33421 aagctgccct gcattaagta ataagaacat ccaagcaaaa atagctcctc atgtttttga
    33481 cttggctgga cttattattg caaatgtaag cttttgaaca ccgtttacca agaggttgtg
    33541 aatctgccgt ttaactctga gtcacaagga acaatttcaa aaaacagctt ttcatgtttg
    33601 atgaatattg tgacttgtga ccgagaagtt ggcaggagaa aaccgtttat acgaaaaaag
    33661 ggactgtgac aaatcgtgtc acagtccctt ttttatagtg ttttttatag gtagtatttt
    33721 ttagcaactg ttaagtcatc atttaattca taaacaagtg gttgacctgt tggaatttca
    33781 agatccatga tgtcttcgtc agagatacct tcgatatgtt tagctagggc gcgtaatgag
    33841 ttaccatgtg cagctactaa aacagttttg ttgtctagta atgctggagc aatttcatct
    33901 tgccagaatg gcaaagcgcg ttctaatgtc actttcaagt tttctccacc aggaatatcg
    33961 cgtttgtcta acattgcgta acgacggtca tttgctgcag aaccttcgtc agtttcttcc
    34021 attaatggag gaagagtatc gtaagaacga cgccagatgt gcacttgttc gtcgccgtat
    34081 ttttcagctg tttctttttt gttcaaacct tgtaatttac catagtgacg ttcgtttaag
    34141 cgccatgatt tgatttgtgg tacccaaagt tgatctgaat attctaagat caagttacat
    34201 gttttgattg cacgagttaa aacagaagtg taagcaacat caaattcgat tccagcttct
    34261 ttgattttgc gtccgccttc ttttgcttct tcgattcctt ctggtgctag atttacatca
    34321 gcccaaccag taaattggtt caatgcattc cattcactaa gaccgtgacg agaaaaaact
    34381 aattttggca tgtttagctc tccttttaag ataggtttat atttctgaaa ttttcagttc
    34441 tgttttattg tacaattttt tggaagagat ttccatcgaa aaattagata agattctatg
    34501 agaaaacaag tagagaatat aaaaaaacga acagtgccca cgcaactgtt cgtttttagg
    34561 tattagatgc ataattgctc gatttctttt tcaggtaaat tgatatattt ataacatgtt
    34621 ccaactgaaa caccgcattt tgaagaaata aattggatcg tttctttttt ttcataatag
    34681 agacgtcgga tttttttgat cgtttttgca tcgatttttg gtcttccgcc gatttttcct
    34741 tttttacgag cttcatctaa tccaactaat gtacgttctt tgatcaatgc gcactccatg
    34801 tttgctaggt tttccattaa ttggaaatag atttttccca tttcgcgcgt atcgattcct
    34861 tcatcaagac taatcaagtg cagcccgcga tctttgaata attgcgtgag ttctgttaat
    34921 tgccgcgtag atttgcctaa tcgatgaagt tggcaaatga ctagtgcatc gccttgttgc
    34981 atgtcagcga tcactgactc caaatgaaca gcagtagaat cattttgttc cacttcatat
    35041 gtctcatgga aaatttcttg acaaccaaag tcagataatt gatcaacctg agttgttaaa
    35101 tcaacgtcat ttatggttgt gcgtgcataa ccaataattt tcatggtgat tcctttctag
    35161 cagtgatttt ctaactggat ataacagtaa aaatgtagca taaagtacgt caaaaagata
    35221 gttttttcgc aaattttccg ctgtcttttt ttattggatg atcaagcagt ttttctttat
    35281 ttacgacgga ttgcgtcaag aatctcaacg cctttttctg agccgacaac tactttagaa
    35341 accatgttta ggaaaagccc atgttctact accccaacaa gttcatctaa ataggtagct
    35401 aagctttctg gctgttcgat gacttctaga tgcagatcaa tgatgtaatg accaccatct
    35461 gtggttaaga cttctccgtt ttcgtctgta cgcaagacgg gttggaatct tttttcttca
    35521 aaaatatgaa gtagctgttg ggagccataa gggatcactt caactgggag tgggaacttc
    35581 ccaagtttat cgactaattt agaagaatca acgatccaaa tcgtttcttt tgagtacgta
    35641 gcgactattt tctcgaaaag caaagcagcg ccgccgcctt tgatcccttg aaaatcagca
    35701 ctgatttcat cagcaccgtc tattgtcaaa tcgactacgg ggacttcatc aatactcttt
    35761 aacggtattc ctaatttttc cgcttgttct tttgtcgcat ttgaagtagt aactcctgtg
    35821 atacgtaaac cttcttcacg catacggcga ccaatctctt ctaccatata ataggcggtt
    35881 gaaccggtcc cgagacctac gatcatcccg tcctttacga atttcgcggc ttcaatgcca
    35941 gctaattgtt ttaaattcat ctttgcgtcc accttttttt agtttgagca tcgtgctttc
    36001 ctcactattt tagcgtgatt tacggtaaaa agataccatt cttttttatt ccaataaagc
    36061 tttttcaaaa aaaattgcat ctcttgttga catgtttttt cattcgtgat attctaacaa
    36121 aggtgcttta tctacaggtt tctgtgaaga aacgtgctga ctgtttatca aagcatattt
    36181 gataaggatg cagacattgc atttattttt tatcacaaaa aaagaaccac ctggatgtgt
    36241 ggaactagac gcaaatcgtg ggaaggagga aacaaggaat gcctacaatt aaccaattag
    36301 tacgtaaacc tcgtaaatca aaggtggaaa aatctaattc acctgctttg aacaaaggat
    36361 ataacagctt taagaaaact caaactaacg taaactcacc tcaaaaacgt ggggtagcaa
    36421 ctcgtgtggg tacaatgaca cctaaaaaac cgaactcagc tttacgtaaa tatgcacgtg
    36481 ttcgtttgtc aaacttaatt gaagttactg cttatatccc agggattggt cataacttac
    36541 aagaacacag tgttgtatta ttacgcggtg gtcgtgtaaa agacttacca ggggtacgtt
    36601 accatatcgt tcgcggtgct ttagatactg ctggtgttaa cgaccgtaaa caaagccgtt
    36661 ctaaatacgg aactaaaaaa cctaaagctt aattttaatt attaaacaaa tgaaacttgc
    36721 ttctactata tagaagtaat tactatgaac aatatttcgg aaggaggagt tacggatgcc
    36781 acgtaaaggt cctgttgcaa aacgtgatgt tttaccagat cctatttata actcaaaatt
    36841 agtaactcgc ttgatcaacc gtgtaatggt tgacggaaaa cgcgggattg cagctaacat
    36901 tatctataat gcctttgact tgatcaaaga atctacaggt aacgatccat tagaagtgtt
    36961 tgaacaagca atgaaaaacg ttcaacctgt tcttgaagtt aaagcacgtc gtgttggggg
    37021 ttcaaactac caagtaccag ttgaagttcg ccctgaacgc cgcgttactc taggtcttcg
    37081 ttgggtagta aactacgctc gcttgcgcgg tgaacacaca atggaagaac gcttagcaaa
    37141 agaaatcatg gatgctgcaa acaacacagg tgcttctgtt aaaaaacgtg aagacactca
    37201 taaaatggct gatgccaacc gtgcgtttgc tcactatcgc tggtaagatt ctctctgttt
    37261 ggtcggcttt tataagtcga cctcagatag tgtccttatt tttagcaact agatagtaaa
    37321 gagaggagaa acaaggagaa tgaccagaga attttcttta caaaacactc gtaatatcgg
    37381 tatcatggcc cacatcgatg ctggtaaaac gactgctact gaacgtatct tgtactatac
    37441 tggtaaaatc cataaaattg gtgaaactca tgaaggagct tcacaaatgg actggatgga
    37501 acaagaacaa gaacgtggta ttacgatcac ttctgctgct actacagcac aatggaaggg
    37561 tcaccgaatc aacatcatcg acacaccagg acacgtagac ttcacagttg aagttgaacg
    37621 ttcattgcgt gtacttgatg gtgctgtaac tgttcttgat gcacaatcag gtgttgaacc
    37681 tcaaactgaa acagtttggc gtcaagcaac aacttatggt gtacctcgta tcgtatttgc
    37741 aaacaaaatg gacaagatcg gtgctgactt cttatattca gtatcaactt tacatgaccg
    37801 tttgcaagca aacgctcacc caatccaatt accaattggt gcggaagacg acttcacagg
    37861 aattatcgac cttgtaacaa tgaaggctga aatgtataca aacgatcttg gaacagagat
    37921 cgaagaaaca gaaattcctg aagaataccg cgaattagct gaagaatggc gcgaaaaatt
    37981 ggttgaagct gtagctgaaa ctgatgaaga acttactttg aaatacttag aaggtgaaga
    38041 aatcactgaa gctgagttaa aagaaggtat ccgccgcgca acagttaacg tagaattcta
    38101 cccagtacta tgtggttcag catttaagaa caaaggggtt caattactat tggacgctgt
    38161 tcttgattac ttgccatcac cgttagatat cccagctatc aaagggattg accctaaaac
    38221 tgatgaagaa gtagaacgtc ctgcagacga cagcgctcct ttctcagctt tagcatttaa
    38281 agttatgact gacccattcg taggtcgttt aactttcttc cgtgtgtact ctggtgtttt
    38341 acaatcaggt tcatacgtac aaaacgcaac aaaaggcaaa cgtgaacgtg ttggtcgtat
    38401 cctacagatg catgccaact ctcgttcaga aatctctgaa gtttacgctg gagatatcgc
    38461 tgctgctgtt ggtttgaaag acacaactac tggggacaca ctatgtgatg aaaagagtct
    38521 agttattctt gaatccatgg aattcccaga accagttatc caagtcgcta ttgaacctaa
    38581 atcaaaagct gaccaagata aaatgggtgt ggctttacaa aaactatctg aagaagatcc
    38641 tactttccgt gctgaaacaa acgtggaaac aggcgaaaca atcatcgctg gtatgggtga
    38701 acttcactta gatatcatcg ttgaccgtat gcgtcgtgaa ttcaaagttg aagctaacgt
    38761 aggtgcgcct caagtatctt accgtgaaac tttccgtgct ggcactcaag ccgaaggtaa
    38821 gtttgtacgt cagtctggtg gtaaaggtca atacggtcac gtatggattg aatttacacc
    38881 aaatgaagaa ggtgctggtt tcgaatttga aaatgcgatc gtcggtgggg ttgttcctcg
    38941 tgaatacatt ccagctgttg aaactggttt gaaagatgct atggaaaatg gtgtcttagc
    39001 tggctatcca ttagtagata tcaaagctaa actttacgat ggttcatacc atgatgtcga
    39061 ttcaaatgaa actgccttcc gtgttgctgc ttctatggca ttacgtgcag cagctaagaa
    39121 agctaatcca gtaatccttg aaccaatcat ggctgtagaa gttgttatcc ctgaagatta
    39181 tttaggtgat gttatgggtc acgtaactgc tcgtcgtgga cgtgttgaag gtatggaagc
    39241 tcgcgctggc ggccaacaag ttgttcgtgc gatggttcca cttgctgaaa tgtttggtta
    39301 tgctacaact cttcgttctg ctactcaagg tcgtggtaca tttacaatga catttgacca
    39361 ctacgaagat gtaccaaaat cagtacaaga agaaatcatt aagaaaaacg gcggaaaagc
    39421 tgaataattt cttaaaaccg gatagtcctg caaagagatt atccaaagag actatatttt
    39481 taatatagtt tcgtgtaaaa taattatcga tgatatgggc atgtggtgta ccttgtgtac
    39541 atcatatacc tatcagacaa ataaaaaata tattgtattt ttaggaggac attttaaaat
    39601 ggcaaaagaa aaatttgacc gttctaaacc acacgttaac attggtacta tcggacacgt
    39661 tgaccatggt aaaactacat taacagctgc aatcacaact gtactatcta agaaaaacgg
    39721 cggccaagct atggcttacg atcaaatcga tggtgctcca gaagaacgcg aacgcggaat
    39781 cacaatctca acagctcacg ttgagtatga aacagataca cgccactacg ctcacgttga
    39841 ctgcccagga cacgcggatt acgttaaaaa catgatcact ggtgctgctc aaatggacgg
    39901 agctatcttg gtagtttctg ctgctgacgg cccaatgcct caaactcgtg aacacatcct
    39961 attgtctcgt caagttggtg ttccttacat cgttgtattc ttgaacaaag tagacatggt
    40021 tgatgacgaa gaattactag aattagttga aatggaagtt cgtgacctat taacagaata
    40081 cgaattccct ggtgacgatg ttcctgtagt tgctggatca gctttgaaag ctctagaagg
    40141 cgacgcttca tacgaagaaa aaattcttga attaatggct gcagttgacg aatacatccc
    40201 aactccagaa cgtgacaacg acaaaccatt catgatgcca gttgaagacg tgttctcaat
    40261 tactggacgt ggtactgttg ctacaggtcg tgttgaacgt ggacaagttc gcgttggtga
    40321 cgaagttgaa gttgttggta ttgctgaaga aacttcaaaa acaacagtta ctggtgttga
    40381 aatgttccgt aaattgttag actacgctga agctggagac aacattggtg ctttactacg
    40441 tggtgttgca cgtgaagaca tccaacgtgg acaagtttta gctaaaccag gtacaatcac
    40501 acctcataca aaattctctg cagaagtata cgtgttgaca aaagaagaag gtggacgtca
    40561 tactccattc ttcactaact accgtccaca attctacttc cgtacaactg acgtaacagg
    40621 tgttgttgaa ttaccagaag gaactgaaat ggttatgcct ggcgacaacg taacaatgga
    40681 agttgaatta atccacccaa tcgctatcga aaacggtact aaattctcaa tccgtgaagg
    40741 cggacgtaca gttggtgccg gtgtcgttac agaaatcaaa gcttaattca cttaagtttt
    40801 aaagtaaagc aacatttatt cggacgtaat cgctcggaac gaaggtctta ggatctttgt
    40861 tccgagcttt tttatttatt gcaggatcag gaaaaaagac aggagtatta taaatagaag
    40921 aaacacgaaa taaaagagtc agtattttct aaatgaaact ttatgaaaac aaaatgtttt
    40981 ttacaagaaa aagccttgct ttgtgagttt atatatatta taatgacaaa ggtgcgttta
    41041 ctttagtgaa ttgcacagac gtaatcagaa tgatttcgtc ggctaagaaa cgagaggttg
    41101 cgacacgccc ggacgctttg ccacgaacga gcgtgacgga aattttcgtg gagctatgtc
    41161 tacttttcaa aataggcgaa ggagggaaca agatggcaaa acaaaaaatt cgtatccgtt
    41221 taaaagcgta tgaacaccgt attttagatc aatcagcgga taaaatcgtg gaaactgcaa
    41281 aaagaactgg agctagcgtg tctggtccaa ttccattacc aactgaacgc agtctttaca
    41341 caatcatccg tgcgactcat aaatacaaag attcacgcga acaattcgaa atgcgtacac
    41401 acaaacgtct tatcgacatt gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc
    41461 tagacttacc atctggtgta aacatcgaaa tcaaattata aaactaaaac aaaaataatg
    41521 gaggtgtact catgaccaaa ggaatcttag ggaaaaaagt gggaatgaca caaatcttca
    41581 ctgaatctgg tgaattaatt ccagtaactg ttgtagaagc tactccaaac gtagtactac
    41641 aagtgaaaac aatggaaacg gatggctacg aagctattca agttggttac caagatatgc
    41701 gtgaagtttt atcaaacaaa cctgcgaaag gtcatgttgc aaaagcaaac acggctccta
    41761 agcgcttcat tcgtgaattc aaaaatgttg agctaggaga atatgaagta ggaaaagaaa
    41821 ttacagtaga tgttttccaa gcaggagaca ttattgatgt aacaggtact acgaaaggta
    41881 aaggattcca aggggttatc aaacgccacg gacaaagccg cggaccaatg gctcacggtt
    41941 ctcgttacca tcgtcgtcct gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa
    42001 acaaacgtct tgctggccgt atgggtggca accgcgtaac tatccaaaac ttggaagttg
    42061 tacgtgtcga tgcagaaaga aatgttatct tgatcaaagg taatgttcct ggagctaaaa
    42121 aatctttaat tactatcaaa tcagctgtga aagctaaata attgtaggaa gaaaggagga
    42181 actaaggaat gccgaatgta gcattattca aacaagatgg aagccaaaac ggtgaaatca
    42241 cacttaacga agaaatcttc ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg
    42301 taatgcaacg tgcgtcatta agacaaggaa cacacgcggt taaaaaccgt agcgctgttc
    42361 gcggcggcgg acgtaaacca tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta
    42421 tccgctcacc acaatggcgt ggaggtggcg tagtctttgg accaacacca cgttcttaca
    42481 gctacaaact tcctaaaaaa gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag
    42541 ttgctgaaaa caacttggta gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag
    42601 aattcaaaca agttcttgct aacttatcta tcgactctaa agtattggtt gttctagaaa
    42661 aaggtaacga ctttgctgct ttatcagcac gtaacttacc aaacgtttct gtagtaactt
    42721 ctgataatgt gagtgtgcta gacgttgtat caaatacaaa agtgttagca acacaaactg
    42781 ctcttactca aattgaggag gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc
    42841 agtgatcact gaaaaatcaa tgcttgccat ggatgacaag aaatacactt ttgaagtgga
    42901 cactcgcgca aacaaaactt tagtaaaaca agcggtagaa gctgcttttg acgttaaagt
    42961 caaaaacgtg aacatcgtga acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg
    43021 atatacaaaa aaacgtcgca aagcgatcgt tacattgact gaagattcaa aagaaatcca
    43081 attattcgaa gctgctgaat aagcactaat agataactca ttaaattagg agggaaaaac
    43141 gtggcgatta aaaagtacaa acctacctca aatggtcgtc gtaacatgac aggttctgat
    43201 tttgctgaaa tcacaacatc aacacctgaa aaatcattgt tacaaccatt gaaaaaccat
    43261 gctggacgta acaacaacgg ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc
    43321 caatatcgcg tgatcgactt caaacgtaac aaagataacg ttgttgcaac tgttcaaacg
    43381 atcgaatatg atccaaaccg ttcagctaac atcgcgttag tacactatga agatggagtg
    43441 aaagcttaca tcttagcacc taaaggacta gaagtgggta tgaaacttgt ttcaggtcca
    43501 gaagcagata tcaaagtcgg aaatgctctt ccattagaaa acattccagt tggtactgtt
    43561 atccacaaca ttgaaatgaa acctggtaaa ggtggacaat tgatccgttc tgctggtaca
    43621 agtgctcaag tacttggtaa agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa
    43681 gttcgtatga tcttagctgc atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac
    43741 gaattaatca acatcggtaa agctggacgc tctcgttgga tgcgtaaacg cccaactgta
    43801 cgtggtagcg taatgaaccc taatgatcac ccacacggtg gtggtgaagg taaagctcct
    43861 atcggacgta aagcaccagt ttctccttgg ggtcaaccag ctcttggtta caaaactcgt
    43921 aacaaaaaag ctaaatcaga caaacttatt gttcgtcgtc gcaaaaataa ataattactt
    43981 tgaccatgtg tcgcacattt tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga
    44041 ccttttgtcg atgagcattt aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa
    44101 aaagttatca aaacttggtc acgccgttca acagttttcc caagttttgt tggatatacc
    44161 atcgcagttt atgatggacg taaacatgta ccagtttaca tccaagaaga catggtagga
    44221 cacaaattag gtgaatttgc acctacaaga acttatcgtg gacatgctgc tgacgataag
    44281 aaaacgaaac gctaatttga ggggaggata aatccaaatg gcagaacaaa tcacatcagc
    44341 taaagcaact gcaaaaacag ttcgcacttc acctcgaaaa gcccgtttag taattgacct
    44401 tatcagaggt aaaagtgtcg cagatgcaat ttcaatcttg aaattcacac caaacaaatc
    44461 tgctggaatc attgaaaaag tattgatgtc agcagttgcg aatgcagaaa ataactttga
    44521 cttagatgtt gaaaacttgg tagtaagcga agcttttgtt aacgaaggac ctacaatgaa
    44581 acgtttccgt cctcgtgcaa aaggatcagc ttctccaatc aacaaacgta caagtcatat
    44641 cacggtagtc gtatcagaaa aataaggagg gataatcagt gggtcaaaaa gtacatccaa
    44701 ttggaatgcg tgtaggcatc atccgcgact gggatgctaa atggtatgct gaaaaagagt
    44761 atgctgagtt cttacacgaa gatttaagaa tccgtaaatt tatttcaact aaacttgctg
    44821 atgctgctgt atcaacagtt gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc
    44881 acacagctaa accaggtatg gttattggta aaggcggttc tgaagtcgaa agcctaagaa
    44941 aagaattaaa caaattaact ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac
    45001 cagatctaga tgcaaaatta gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg
    45061 ctttccgtcg cgctcaaaaa caagccatcc aacgctcaat gcgtgctggc gctcaaggga
    45121 tcaaaactca agtatctggt cgtctaaacg gagcagatat cgctcgttca gaaggatact
    45181 cagaaggaac tgttcctctt catactttac gtgcggacat tgattacgca tgggaagaag
    45241 cagatacaac atacggaaaa ctaggagtta aagtgtggat ctatcgtgga gaaattcttc
    45301 caactaaaaa aaacactgag aaaggaggga aataatcatg ttagtaccta aacgtgtaaa
    45361 acaccgtcgt gaattccgcg gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc
    45421 attcggtgaa tacggtttgc aagctgttga ttcacattgg atcacaaacc gccaaatcga
    45481 agctgctcgt atcgcaatga ctcgttacat gaaacgtggt gggaaagtat ggattaaaat
    45541 tttccctcac aaatcttata ctgccaaagc aattggggta cgtatgggtt ctggtaaagg
    45601 ggcacctgaa ggatgggttg caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg
    45661 cgttcctgaa gaagtagctc gtgaagcgtt acgtctagct tctcacaaat taccaatgaa
    45721 aactaagatc gtaaaacgtg aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca
    45781 gagaattaac cactgccgaa atgcttgatc aagaaaaaca attaaaagaa gaattgttta
    45841 atcttagatt ccaattagca acaggtcaat tagaaaacac tgcacgtatt aaagaagtac
    45901 gtaaatcgat tgcacgcatc aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg
    45961 aggccattaa gcgtatgact gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg
    46021 tttcagacaa aatggataaa acaattaccg ttgctgtcga aacaaagaaa aaccacccta
    46081 tctatggcaa acgcatgaac tattctaaga aatacaaagt gcatgatgaa aacaacacag
    46141 caaaagttgg cgacatcgtg agaattatgg aaactcgtcc attatcagct acaaaacgtt
    46201 tccgtttgtt ggaagtagtc gaagaagcag ttattatcta ataacacgag attttcctat
    46261 atagattgaa tgcaaaatct gaaaggagga tacacaacgt gatccaagca gaaagtcgtt
    46321 taaaagtcgc tgataactca ggcgcacgtg aaattttgac gatcaaagtc cttggtggat
    46381 ctggtcgtaa aactgctaac atcggtgatg tgatcgttgc tacggttaaa caagcaacgc
    46441 caggtggggt tgtcaaaaaa ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag
    46501 gagctcgtcg tacagacggt tcatatatta aatttgatga aaatgctgca gtgattattc
    46561 gtgatgataa aagccctcgt ggaacacgta tctttgggcc agttgcacgt gaactacgtg
    46621 aaaacaactt catgaagatc gtttcactag caccagaagt tttataatct tgagacactt
    46681 atcaaaggag gtgcgaaaca gttatgtttg ttaaaaaagg cgataaagtt aaagttatca
    46741 ctggaaaaga caaaaacaaa gaaggcgttg tactagcagc gttcccgaaa aaagataaag
    46801 ttattgtcga aggtgtaaat gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc
    46861 aaggtggaat tgttgagatg gaagcgccaa ttcatgtttc taacgtgatg gtggttgact
    46921 ctactggtgt agctggccga gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt
    46981 ctaaaaaaac cggtgaagtt ttagataaat aaaagtttaa ggaaggaggg tcttactgaa
    47041 tgaaccgcct aaaagaaaaa tatcttaaag aagtaactcc atcattgatg gaaaaattta
    47101 actatagctc tgttatgcaa acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg
    47161 gtgatgcggt atcaaacgct aaaaacttag ataaagcagt tgaagaatta actttgatca
    47221 ctggtcaaaa accaatgatt acaaaagcta aaaaatcaat cgctggattc cgtttacgtg
    47281 aaggaatgcc aattggtgca aaagttacat tgcgcggaga aagaatgtac gaattcttag
    47341 acaaattggt ttctgtttca ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag
    47401 cctttgacgg tcgtggaaac tatactttag gtattaaaga acaattgatc ttcccagaag
    47461 tagattatga tttagtagat aaagtacgtg gtatggacat cgttattgta acaacagcaa
    47521 actctgatga agaatctcgt gagttgttga cacaattagg catgccattc caaaaataat
    47581 taaaggaggc gaactacgtg gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa
    47641 aattttcaac acaagcttat actcgttgcg aacgttgcgg acgtccacat tcagtttatc
    47701 gtaagttcca tctttgccgt atttgcttcc gcgaacttgc ctataaaggt caaattcccg
    47761 gcgtgaagaa agctagctgg taaaaagtaa attcgcataa gaaggaggta aaagatcaat
    47821 ggtcatgaca gatccaattg cagattttct aactcgtatc cgtaacgcaa acatggttaa
    47881 acatgagtct ttagaagtac ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa
    47941 acgtgaaggt ttcgttcgtg atgttgaata catcgaagat gacaaacaag gcgtgatccg
    48001 tgttttccta aaatttggta aaaacggcga acgtgttatc acaaacttaa aacgtatctc
    48061 taaaccaggt ttgcgtgctt atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt
    48121 aggtatcgca atcatttcga cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa
    48181 aaatatcggc ggcgaagtta tcgcttacgt atggtaatca agtagaatct acaaggaggt
    48241 gtctttaagt gagccgtatc ggaaataaag tcgttgttat ccctgaagga gtaacagtta
    48301 ctcaagacgg aaacaacgtt acagttaaag gaccaaaagg tgaattgact cgtacttttt
    48361 cagcagatat caaaatgaat atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca
    48421 gtaaagaaat gaaaacaatt catggaacaa ctcgtgcgaa cttcaacaac atggttgtag
    48481 gtgtcagcga aggtttccaa aaagcgttag aactaatcgg ggttgggtac cgtgcacaat
    48541 tacaaggatc aaaacttgta ttgaacgttg gttactcaca tccagtagaa atcacaccac
    48601 cagctggagt aactgttgaa gtaccagcta acacacaagt aattgttaaa ggtgcgaaca
    48661 aagaagaagt tggcgaatta gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata
    48721 aaggtaaagg tattcgttat gttggcgaat atgtacgccg taaagaaggt aaaactggta
    48781 aataatcgtt tagaaaaatt gcatagaagc cagcagcagg aaaaaggcat ttggctgaag
    48841 tttaccttca aaaaaataca tttttacttg tgccgcagct tctatttttc gaaacgtatt
    48901 tactgcttga aatagtagta caataaaaat aaagaggtga caattgtgat tacaaaacca
    48961 gataagaaca aaacacgtca aaagagacat cgtcgtgtac gtaacaatat ctctggtact
    49021 gctgagcgcc cacgcttgaa cgtttttcgt tctaacaaaa acatctacgc tcaaattatt
    49081 gatgacgtag cgggtgtaac gctagcaagt gcctctacct tggataaaga aatttcaggt
    49141 ggaacaaaaa cagaagcagc acaagctgtc ggtaaactag ttgctgaacg tgcagctgaa
    49201 aaaggcatta aagtagtagt ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa
    49261 gctttagctg aagctgctcg cgaaaatgga ctagaatttt agaagaagga ggaataccat
    49321 tcatggttta tatcgatcca aaacatttgg aattagaaga ccgcgttgtt gcaattaacc
    49381 gtgtaacaaa agttgttaaa ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg
    49441 gtgacaaaaa cggacacgta gggtttggta caggtaaagc tcaagaagtt cctgaagcaa
    49501 tccgtaaagc aattgaagat gcgaagaaaa acttagttga agtacctatg gttggttcaa
    49561 caatcccaca cgaagtaatc ggtgctttta gtggtggtag aatcctaatg aaacctgctg
    49621 tagaaggttc tggggttgct gctggtggac cagttcgtgc cgtattagaa ttagctgggg
    49681 tagcagatat cacttctaaa tctttaggct caaatacacc aatcaacgtt gttcgcgcaa
    49741 cagttgaagg tttgaaacaa ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat
    49801 cagttgaaga attaatcgga taaggaggac aacaataatg gctgaattaa aagttacttt
    49861 aaaacgcagt attatcggac gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct
    49921 tacaaagatt aacagttcag tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa
    49981 tactgtttct cacctagtgg acgttgaaga aatttaattt agaaaaatca taactagaac
    50041 attaaggagg tgccaaacct atgaaacttc atgaattaaa acctgctgaa ggttcacgcc
    50101 aagtacgtaa ccgtgttggt cgtggtactt catctggtaa cggaaaaact gccggacgcg
    50161 gacaaaaagg acaaaaagct cgttcaggcg gcggtgtgcg tttaggattt gaagggggac
    50221 aaacaccatt gttccgtcgt ttaccaaaac gaggattcac aaacgtgaac cgtaaagact
    50281 atgcagtcat taatcttgat gtattgaacc gctttgaaga cggagctgaa gtaactcctg
    50341 ttgctttagt tgaagctgga atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta
    50401 atggggaact aaacaagaaa ttaactgtga aagcagcaaa attctctaaa gcagctcaag
    50461 aagcaattga agcggctggt ggatcaatcg aggtgatcta atgtttagac tattaaaaga
    50521 tgcttttaaa gtaaaagaca ttagatcgaa aatcctattt actgtatttg tgttgtttgt
    50581 atttcgccta ggtgcacata ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct
    50641 ttcttctttg ccatttttca acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt
    50701 ttccattttc tcaatggggg tttcaccata cattactgct tctatcgtca ttcagcttct
    50761 tcaaatggac atcgtgcctc gatttgttga atggtcgaaa caaggggaag ttggtcgtaa
    50821 aaaactgaat caagcgactc gatatctgac attagtattg gcatttatcc aatctgtcgg
    50881 tatcactgct ggattcaatc aatacgctca attaggtttc gtgaataatc ctaacgtagc
    50941 aacttacgta acgatcggtt tgattctaac agccggtacg atgtttgtta cttggctagg
    51001 agaacagatc acagaaaaag gtatcggaaa tggcgtatca atgatcattt ttgcaggtat
    51061 catttctaga ttgcctgaaa gtatcagaga aatttatgaa gattacttta taaatattga
    51121 tccttcagac atatggaaat ctgctatttt tgtggccatt ttactagtag cggtcttgtt
    51181 gatcgtgaca ttcgtaacat ttttccaaca agctgaacgc aagatcccga tccaatatac
    51241 gaaacgcgta gctggcgcgc ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg
    51301 agttattcca gttatctttg ctagttcgtt tattgctacg ccaaatgctg ttttacaagc
    51361 attgagcggt agattcggtt ctgaaaactg gtacaaagtg atgatggaga tctttaacta
    51421 taatacagca cctggtgcta cgatttatac gattctgatc gttgccttca ctttcttcta
    51481 cgcctttgtt caagtaaacc ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta
    51541 tataccaagc gtacgccctg gtaaggggac tgaagagtat gtctcaagat tactgatgcg
    51601 tttaagtaca gttggtgcag tcttccttgg tttagtggca ttgcttccaa tcattgctca
    51661 aatggtttgg gatcttccac aatcaatcgg attaggcggt acaagcttac tgatcgttat
    51721 cggtgtagct ttagaaactg cgaaacagtt agaaggctta atgctgaaac gtaaatatgt
    51781 tggattcatt gagtaagaaa gcgtgttgag gtttcccctc aacacacgtt ctcacacatt
    51841 tattaggagg gaaaacaatg aacctcattt taatggggct gccaggcgca ggtaaaggaa
    51901 cacaagctga aaaaatcatt gatgcttatg gtattccgca catctcaaca ggagatatgt
    51961 tccgcgcagc gatgcaaaac gaaacagctc ttggcctgga agcaaagtct tatatggata
    52021 aaggtgcatt agttcctgat gaagtaacaa atggaatcgt gaaagagcga ctagctgaac
    52081 cagatacaga gaaaggcttc ttattagatg gctttccacg tacgctagat caagcaaaag
    52141 ctctggacgc aatgctaaaa gatttgaata aaaaaattga tgctgtcatc gatatccatg
    52201 ttggtgaaga aatcttggtc gaacgtctag ccggccgatt tatctgcagc aattgtggag
    52261 caacttacca taaaattttc aaccctacaa aagttgaaga cacatgtgat cgttgcggtg
    52321 ggcatgaatt ctatcaaaga gaagatgata aacctgagac ggttaaaaat cgtctggcta
    52381 tcaacatcaa aaatagtgaa ccaatcttgg cttattataa agaacaaggt ttgctaaaca
    52441 ctattgatgg tgctcgtgaa atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa
    52501 aatagcacga ttgcccgtag ccgacttgca ttatgcagtt actcttgtca agttcaataa
    52561 attatgatag aatatgtcag tccgacttct agagaatcct ctagatgatc cattttgaga
    52621 attttgaggt gggaactgca gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac
    52681 aaggaggtac tgtgcgtggc aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa
    52741 actttgccga atgcaatgtt taaagttgaa ctagaaaacg gacaccaagt tcttgctact
    52801 gtttcaggta aaattcgtat gcattacatc cgtatcttac ctggtgacaa agtaacggtt
    52861 gaattgtctc catacgatct taaccgtggc cgtattactt atcgctttaa ataattgtac
    52921 tccgtaaaac tacaggaggt attatcatga aagtaagacc atcagtaaaa ccaatgtgcg
    52981 aacattgtaa agtaattcgt cgtaaaggac gcgttatggt gatttgccca gcaaatccaa
    53041 aacataaaca acgtcaagga taattggagg tgctataaat atggctcgta ttgcaggagt
    53101 agatattcct cgtgataaac gtgtagtagt ttcacttact tatatctatg gtattggtaa
    53161 cactactgct aaaaagatct tagctgatgc tggtgtatct gaagatgttc gcgttcgtga
    53221 attaacgaat gaacaaacag atgctatccg tgcagaagta gataaattaa aagttgaagg
    53281 ggatcttcgt cgtgaagtga acttgaacat caaacgtttg atggaaatcg gttcttaccg
    53341 tggaatccgt catcgccgtg gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg
    53401 tactcgtaaa ggcccagctc gcgctatcgc tggcaagaaa aaataattct taagtgaagg
    53461 aggttaaaac ttcatggcag caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat
    53521 agaagcaggt attgcacata tccattctac attcaataac actatcatca tgatcactga
    53581 tactcacgga aatgcattag cgtggtcatc agctggttca ttaggtttca aaggaagcaa
    53641 aaaatcaact ccttttgccg ctcaaatggc agcagaaact gctacaaaag cagcaatgga
    53701 acacggatta aagactgttg aagtaacagt taaaggacct ggttctggac gtgaagcagc
    53761 aattcgttca ttacaagcta caggtttaga agtgactgca attcgtgacg tgactccagt
    53821 tcctcataat ggtgcccgcc ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt
    53881 gagttttatc agtaacgtca ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa
    53941 gaatgattga gttcgaaaaa ccaagaatcg caaaaattga tgaagaaaaa gattatggca
    54001 agttcatcgt tgaacctctt gaaagagggt atgggactac tttagggaat tccctacgtc
    54061 gtattttatt atcttctttg ccaggtgctg ccatcactaa tattcaaatc gatggtgtac
    54121 tgcatgaatt ctctaccatc aaaggtgtta gagaagacgt cactcaaatc atcttgaaca
    54181 ttaaaggctt agcgctgaaa atgtatggcc aagaagaaaa aacccttgaa atcgatatta
    54241 ccggacctgc tacagtaact gctggcgata ttatcgttga tagtgatgta gaaattctta
    54301 acaaagatat gtacatctgt agtgtctctg aaggagctac gttccatgct cgcttaacag
    54361 tgaaacctgg acgtggttat gttcaagcag atgaaaataa aaaagaagat atgccaattg
    54421 gcgttcttcc agtcgattca atctacacac ctgttcgtcg tgtgaactat caagttgaga
    54481 acacacgtgt tggacaccgt gaagattttg ataaattgac gatggagatt tggacagatg
    54541 gttcaattga accgttggaa gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg
    54601 atatttttgt gaacttaact gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag
    54661 aaacacaaaa agaaaaaatg ttggaaatga cgatcgaaga gttagacttg tctgttcgct
    54721 cttacaattg tttgaaacgt gcaggaatca atactgtaca agaacttaca aataaatctg
    54781 agcctgaaat gatcaaagtc cgtaacttag gacgtaaatc attagaagaa gttaaagcaa
    54841 aattgcacga cttaggttta ggtttacgta aagaagatta aaacctttta cgaaggaggg
    54901 aaaccaacgt gagttatcgt aaactaggac gcacatctag ccaacgtaaa gcgatgttgc
    54961 gtgatttaac aactgattta ttaatcaacg aacgtattgt gactactgaa gctcgtgcga
    55021 aagaagttcg ctcaactgca gaaaaaatga tcactttagg taaacgcgga gatttgcatg
    55081 cacgtcgtca agctgcggct ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg
    55141 aggacatcgt cattgaatca gctttacaaa aactgttcaa cgatattgca cctcgttacg
    55201 cagaacgtca aggcggatac acacgcattt tgaagacaga accaagacgc ggtgatggtg
    55261 caccaatggt tgtcttagaa cttgtctaaa atcacactaa taacatcact ttatagatga
    55321 ttcttttaga gtgttatgat gttggaagat atttttccga gtctagctca gcgctgctcc
    55381 tcaagcgaat atcgcttggg gagtaagcac tcatcataaa gtgttttttt ataccttcaa
    55441 ttacctgtca tgacagatat gtttgaaggc ataaaaaaac attttaagcg agaaataatt
    55501 gaaaattttg tctttttttg atagtgttag taggaacttt aggatgaaga aggagtaatc
    55561 atggagccaa ttattgaatt agaaaagata aattataaat accagccaga tgatcttcgc
    55621 cccgcattga aagatgtctc ctttacaatt gataaaggtg agtggatcgc tattattgga
    55681 cacaatggtt caggaaaatc gacacttgcc aaaacgatca atggattgct tctgccagaa
    55741 tcagggatcg tgaaagtggg aaatcaaata ttggatgaag aaaatatttg gacgatccga
    55801 cagatggttg gaatgatttt tcaaaatcca gacaatcagt ttgttggttc gacagtagaa
    55861 gatgacgttg cttttggtct tgaaaatcaa gggattccca gagaagaaat gctagtgcgt
    55921 gtgaaagatg cacttgagaa agttagaatg gctgagtttg cttcacgcga gcctgctcgt
    55981 ttatcaggag ggcaaaaaca acgtgttgcc attgccggcg tggttgcctt acgacctgat
    56041 atcattattt tagatgaagc aaccagtatg ctagatccag aaggtcgtga agaagtgatc
    56101 tctacgatca agaagatcaa agaagaaagt caattgaccg ttatatctat cactcatgat
    56161 attgatgaag cagctaatgc caatcggata ctagtgatga gacaaggcga acttgtccgt
    56221 gaaggtacac caaaagaaat tttttctgct ggtcctgaac tgatcgactt aggtctagat
    56281 ctaccatttc ctgaaaaact gaagagcgca ctgaaagaac gtggggttga tgtgcccagt
    56341 gaatatatga cagaagaaag gatggtggat tggttatgga catccgtttt gaacaagtag
    56401 acttcactta tcagccgaat acaccatttg aacaaagagc cttatttgac atcaatatga
    56461 cgatcaaaga aaacagttat actgcattag tagggcatac cggaagcggg aaatcaacct
    56521 tacttcagca tttgaatgcg cttgttaagc caacaagcgg tacagtccat attggagaac
    56581 gagatattca gccggatacg gataataaga atttaaagcc catccgaaaa aaagttggca
    56641 tcgtctttca gtttccagaa gcacagctat tcgaagaaac ggtagcaaaa gacattgctt
    56701 tcggtcctaa aaactttggt gtcagcgaag aagaagcact agtcctagca aaagaaacat
    56761 tagaacaagt tgggctggat gaaagctatt tggaacgttc gccatttgaa ctttcaggag
    56821 ggcaaatgcg tagagtagca atcgctggtg tgcttgccat gaggccggaa gtacttgtat
    56881 tggatgaacc aacggcagga cttgatcccc agggcagaaa agaaatgatg gagatgtttt
    56941 ggcgtcttca taaggaacag cagatcacta ttgtattagt tacgcattta atggatgatg
    57001 tagccaattt tgcagattat gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg
    57061 agccgcaaga ggtctttcaa aacattgaat ggctaaaaga aaaacaacta ggcgtaccta
    57121 ctgccaccga gtttgcagaa gaattaatgg ctaaagggat gaactttgct accttgcctt
    57181 tgacagctga agaattagca gacgctatcg tccattatgc tggaggaaat gcccatgatg
    57241 aataaattga tatttggtcg ttatatgcct ggagattcct tgatccatcg attggatccc
    57301 cgagctaaat tattagccag tttttatttt atcggaatca tttttttagc aaataattgg
    57361 gaaacgtacc ttttgttggc atttttcaca ttactttctg tcttcttgtc aaaagtagat
    57421 ttgaaatttt ttatccgagg cattcgccca ttgatctggc taatcctctt cactgtagct
    57481 ttgcaggtct tgtttacaag tggcggagaa acttattgga gttggggtgt tttccatatc
    57541 actgaatttg gtgtgatgaa cggcctcttt attttctgtc gattcgtgtt gatcattttt
    57601 atgtcgactc tactcacgct tactacaccg cctttggaat tatcggatgc gattgagtac
    57661 ttgcttcgtc cattgaaagc cgtacggttc ccagtccacg aaatttcatt gatgctgtcg
    57721 attgctcttc gttttgtgcc tacattgatg gacgaaacag aaaagatcat gaacgctcag
    57781 cgcgctcgcg gtgttgattt tggtgaagga aacctagttc agaaaatgaa agcagtcatt
    57841 cctttgctga ttcctttatt tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct
    57901 atggaagcaa gaggctacaa aggtggggaa ggaagaacga aatatcgtgt attgcattgg
    57961 cataatagag acacgatggt tatcattgct tttgtattat taactgtgct actgatcttt
    58021 ttaagaggat aaacgttcag tgggccgcta tctattcttt tcttgctgat ctgtttgcaa
    58081 gaaaggatgc aagcagtgta tgacaagaaa tattagggtc tgtggcagac taaggtcaca
    58141 ggcctctttc ttttatctga aaagaaagaa cgaaaaaatt ttatagaaaa atcattattc
    58201 cagataacct tttaggaaca aaggagagaa aaacatggta cgttacaaag caatcattgc
    58261 gtacgacgga acaaatttta atggattcca aaaacagcca aatgggcgta ctgttcaaga
    58321 agaagtagaa aaaacattac aaaaaatggc aaatggaaaa gaaatcacgg tctttggttc
    58381 gggaaggaca gatgccggag tacatgcgat cgggcaagta atccattttg attatccaga
    58441 ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc cagtcaccag aggatattgc
    58501 tgtaagacaa gtagaaattg tttcagaaga cttccacgca agatatttgg tcaaagaaaa
    58561 gacgtatcaa tttcgagtgg atatagggaa accacgcagt ccttttcgac gccattatgc
    58621 aagttatttt ccttacccac ttgatttgga aaaaattcag cgggcgcttc ctgatttatt
    58681 agggactcac gatttcacct ctttttgtgc atcaggaagc tcgatagagg ataaaatacg
    58741 tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa gacgaattgt tgtttacatt
    58801 taggggaaat ggcttcttgt ataagatgat acggatctta gtaggaacgc ttttgaaaat
    58861 tggcaatggc cgattgcctg aagatagtat cccagatatt attgcgaaaa aagatcgtaa
    58921 tgcagcagga cctacagcac accctgaagg actttatttg tatgaagtga aatatgaata
    58981 agaggttatg atagaagtgg tcagcttcaa gaaataagaa ggtatttacg aaaattactt
    59041 ctcaaaattt tgcaaaattt cggcttattt tcgaagaagc tacttctgga acaccgttta
    59101 agaaagaggt cgtgagcctg tcatttaact ctgagtcaca aagagcaatt tcaaaaaaca
    59161 gcttctcatc tttgatgaat atcgtgactt gtggacgagg cgttgataag tgaatcatct
    59221 ttttgttacc tattttttct gtaaccaaaa aacgatggaa cgttgttttg attgcccttg
    59281 gtgcggacag tctgaacagg ttccatcgtt tctttatttt ctacgtcttc ttctgtgtgt
    59341 gtttcgtggt tgttcttcta ttgctggatc aatcgtgcca taaaaggggc gattgcggtc
    59401 aaggtaccag acataaagaa taaacaatgc aatacatagg acaaaaagga ttgcacctat
    59461 cgtaaatcct tcaggcaagt aactgaaagt gacagtatgt ttacctgctg gaacttttat
    59521 catcaagaat gcgtctttga aattgctgac cttgactggt ttcccatcaa ttttagcttt
    59581 ccatcctttg tcataaggaa tagttgtcac caacatggaa tcttcagcgg tatttacagt
    59641 cccagaagct tttctgccag tggcttccat ttcgacacct ttttctttga tctgattcat
    59701 tgcggcttga taggctacaa catctagacc aacgacttta ggctccatga aacttatttc
    59761 tttcgtccca taaaaacttg cagtaaatgt cactgttgtc tcttgaggat aatagccaag
    59821 atcatagtat tgaccagaaa tgttgatttg cgtttttcgc gatgtaccat tgacagtgat
    59881 cgtcgcacta gaactttcta attgcgcaaa attggttggg aacaaactta agtaagcttg
    59941 tgtatttgca ggcacatgga cttcccaagt gagctctttt ggctggttat ctgctgtttc
    60001 tgagtaagtg acgccagtcg ttgtctttgt gatcgtcgta ttcaactgat tcttcaaagt
    60061 aggtgtatag aatgtaaaat actgttcatt tagaccagac aatgtattga tcaagtttgt
    60121 ctgactggtc aaattatctg tcactggctg ctcaacatca ttaacggaca acggtgcagt
    60181 aaatgctagt ggcaatgcat tgacattctg atacagtgta tagtcgccgc tttgaccagc
    60241 ttggcggaag ccatatttac tgaacgtgct ttcgttttta gaaatgttat atttgattcc
    60301 tgtaaaccca tccatcagca aagtattatt gttataacgg atattcaaat ttgtccctct
    60361 tgaacggaaa cctaatttat ccaggtaaga ggaagaatta cgatttctta tagaagaaaa
    60421 caaactgata ccactgtaac catagttgat cgaatcgttt gcagatactg gatccagatt
    60481 ttccaagcgg taaaacgagt cggaatcttt ttttgtttca tttacaagag ctttcaagtc
    60541 aggataagga tcagtatata aactgcggga agcataattc caatcatcaa gaatgccatg
    60601 gatcatactg ttcgtattga ccagtgcttc agcagacatg atcaataata acaatatact
    60661 cagatgattg aatgaaagtt ttttatgctg ataaaatccc acagcaaaag cataaatccc
    60721 taagaaaacc actgtcaata caaaggaagt catcgtcaca taggtgtagc ttccttcagg
    60781 tttgatgccc catgccaccg caaagagagc agctacgacc aaaatgattc ctaacaacag
    60841 cccaccatcg tcttgttcta tcttttccca tccttttcct gcaagcagga gcactaagaa
    60901 agagaacaga taggcataac ggaataaaaa catattcggt gcatgcatac catgccagaa
    60961 caaattcaat ggaacaagat aaaaacttgc gataagtatg gcgaaaagac tgccgtacaa
    61021 aaatttattt ttcaacggta ctttccgact ggcaaaataa aacagacaga ggactaatgg
    61081 tagcagacct gcgtaaacga acggaatcga tccgtatttt gtcgtgtcat aaacaccaat
    61141 catatttttc atgattagat ccagataaga agtcgcttct gttttcaacg tagtgatctg
    61201 actcagtgcc tcgccatttg accgaagatc cagcactgct ggcaatacaa tgatcattga
    61261 agcgccgcct gccagtaaag aagtgatacc ataaggaaca atcgtttttt tatattctga
    61321 ccagtttgtc aatagacggg cgataaaata taagaaagaa aatacgccaa tcataaaacc
    61381 catataaaaa ctggataaaa acaagagtaa ataactgata aataaaagtt tcggccgttt
    61441 aagatccata acacgatgaa tccccaaaat cactaatgga agataaacaa atgcatccag
    61501 ccacatgatg atctccgaat gtgcagtgat aaatgagatc aatgcgtaac tgacgctaag
    61561 tgcaacatgc ccccagcgag gaatcttgaa cgtacgtgca agaaaccaaa aagccaatcc
    61621 ggcacagccg accttaagca aagtcagaac atacagtgca tctggcatca tctggtttgg
    61681 aaaaaagaac accagtggcg tgaagatccc gcctagatag taagaaatta aagataaata
    61741 attcaatcct agagaagcat tccatgtata aaaaatactt tgctttccaa gaagaacatt
    61801 tcggaagctg gcatgaaaat tagaaaactg tgaaaaggca tcacttgcca aaatacttct
    61861 gctgcttcca ggatagattc cgatacttag ataaacaagt gctaaaatca aaaacggaat
    61921 caggaaacta gctgctgcgt agcgtccgtt ttctctaaag aatgacttta aatttttttt
    61981 catatttatt ttccaccaaa tttctatgaa gttgtattca gtttatcata tccttgtttt
    62041 tctctgctta aaaagagtct agttttcaca aaaaaataaa atttagaata aataacttca
    62101 taatttgttc gtataacaaa aataaacgca aaaaaagggt aggaatcaaa agtcccaccc
    62161 ttaaaaattt ttattaaata aaaaaccgtt cactatctga acggtccaag tatcattcaa
    62221 ttaaacgcgt tcaacttttc ctgatttcaa agcacgagtt gacacccaaa cttttttagg
    62281 ttttccgtcg accataacgc gaactttttg taagttaggt ttaacagtac gttttgttga
    62341 gttcatagcg tgtgaacggt tgtttccact ttttgtcttg cgacctgtaa agtaacaaac
    62401 ttttgccatg gtaatttcct cctttgcctt gatttggagc aatagaataa ttcagctcat
    62461 accagactaa catatcatat agaatgggaa tttgcaagta cattttcata gatacaattg
    62521 acaattgaga agaataattg taaattaaac aaggttatac ctgaaatttt gcaaggtttt
    62581 tgagtacttt gggtaactgc cttttatttc aagttgcgct atgataaaat atgatagaag
    62641 aaaaatggga gttttttacc cgttaaggag gctcattcat ggctgtaaaa attcaaacgt
    62701 cagctggaac cattgaaatt accaatgatg taattgcaac agttgttggt ggcgccgcga
    62761 cagatgtgtt cggtgttgta ggaatggcca gcaaaaatca aattaaagat aatattactg
    62821 agattttgcg taaagaaaat tactcaagag gagtagttgt ccgccaagaa gataatggta
    62881 ttgctgtaga tgtttatacg attatcagct atggtacgaa aatctctgaa gtttcccgca
    62941 acgtccaaga aaaagtgaaa tacaatctag aggcattatt aggcgtaact gccaattcag
    63001 ttaatgtctt tgtacaaggt gttcgtgtac tgccagacta ggcaggagac tggctggtaa
    63061 ctcagcagtc gatctgaagg aggattatct aggtgagtgt aacagaaata agtgcaagcc
    63121 agttccagga aatggtccag gcaggtgcga atcgtctgca agtaaatgca gaatacgtca
    63181 attcattaaa tgtattccct gtgccagatg gcgatacggg aacaaatatg aatctatcta
    63241 tgactagtgg agctaaggca gtagtagatt caacctcaga aaaagtagga gaattagcag
    63301 caatgctttc aaaaggattg ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc
    63361 aattgtttcg tggattttct aagcaaattc cagatgttgt ctcattaaat gcttctgatc
    63421 ttgctgcagc cttcactcat ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag
    63481 aaggaacgat tttgacagta gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa
    63541 gtactgatga tgtcgttgaa gtaatgacag ctgttgtaaa aggagcaaag cgtgctttag
    63601 ctaaaactcc agacttgctt ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc
    63661 aaggactgct gtttgtttat gagggctttt taagtgcatt gaatggagaa ttccaagcgg
    63721 atgaaacata tgaaccttct ccagcagaaa tggatgatat ggtcaatgca gaacatcatc
    63781 gcagtgtcca aggtcaaatg gcgacagaag atatccattt tggttactgt acagaaatca
    63841 tggtaaaaat cggagaagga cctacagtcg atagtacatt cgattacgaa gaattccgta
    63901 actatttaga tggtatagga gattctttac ttgtggtcaa tgatgacgag atcatcaaag
    63961 tccacgtgca tacagaaaac ccaggagaag tcttgaatta tggacaaaaa ttcggttcat
    64021 tagtcaaaat caaagtcgac aacatgcgct tgcagcatga gacgattttg gaacacgatg
    64081 aagaagtgaa cgagtttgcg aaaaaagaaa taccacgtat cccgtatggt atcgtagcga
    64141 tcgctgctgg taaaggcgtc caagagctgt ttgaaagttt aggcgctaat tatgttatca
    64201 gtggtggaca aacaatgaat ccaagtacgg aagacattgt taaagcgatt caagaagtaa
    64261 acgcagataa agtgattgtc ttgccaaaca ataagaacat cttcatggca gctgatcaag
    64321 cagcagaagt agcagatatc ccagtagcag ttgttccttc aagaacgatt tcccaaggat
    64381 tgacagctat gctttcattc aatgatcaag cttctttaga agaaaacaaa gaaacgatga
    64441 cagaaatgtt gtctagcgtt gtgagcggtc aagtcactca cgcgatcaga gatacctcaa
    64501 ttgacggtgt agagatcaaa gaaggagact ttttgggcat gatcgatgga aaaatcctga
    64561 tctctaaccc agatatcaca gcaacagcgt taagtacact agaacaaatg atcaatgagg
    64621 acacagagat cgtaacgatc ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat
    64681 ttgctgagaa actaacagaa aaacatcctg atttggaaat cgagatccac caaggagatc
    64741 agcctgtcta tccttatcta ttttctgctg aataatttct gtgtcagaat atctttctaa
    64801 cacagtattc attcataaaa ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc
    64861 ctttttttgt taaaggaggg aggaaaaatt tatgcgttct ttagatgatc caatcactat
    64921 gctggcagga gtcggagaaa aaagagcagc tagtcttgcc agcttgggca tccaaacgat
    64981 tgaagactta ctgacttatt atccttttcg ctacgaagat attcaggaaa gaaatctaaa
    65041 cgagatccag gatcaagaaa aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat
    65101 gaatcgattt ggttataaaa aaagccgatt gcaatttcgt atgatgcaag aacatgatgt
    65161 gttcaacgtt tcttttttta atcaacctta tctaaaagaa aaagtcattt tatcggagga
    65221 aatcgccgta tacggtaaat gggatgcaaa gcgtaaagcc ttgaacggga tgaagatttt
    65281 aggttctcaa acaatggatg acttttcgcc gatatatcac gtcaacaaat caattcgtca
    65341 aacgacatta gttgatctaa tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga
    65401 aaatctgcca aacaaccttg tggagaaata tcgactgctt gaccgagctt ctgctgtaag
    65461 aagtatgcat tttccaaaag accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt
    65521 tgaagagttc tttttatttc aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga
    65581 aacgaatggt ttggagatcc tttatgatgt ccaaaaattg aaacaattta ctcaaaagct
    65641 accttttgaa ctgacaaatg cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg
    65701 cagtccgcag catatgcagc gacttttgca gggagatgta ggtagcggaa aaacagtggt
    65761 tgccgcgatt gcgttatacg ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc
    65821 tacagaaatc ttggcacaac aacatatgga aagcttgcaa cagctgtttg atcccaatga
    65881 agtaaccatc gcattgatta cggggtcaac gaaagcaaaa gaacgacgtg agctccttga
    65941 aaaactagag caaggggaaa ttaacgtcgt gatcggcaca catgcattga tccaagatgg
    66001 agtcgaattt cagaatttag gtctagttat tacggatgag cagcaccgtt ttggcgtgaa
    66061 ccagcggaaa gtacttcgtg aaaaaggctg gcgaccagat gtcttattta tgacagcgac
    66121 tccgattcct agaacattag ctattacagc atatggtgag atggatgtat ctatcattga
    66181 tgaacttcca gctggacgta tcccgatcga aacacgctgg gtaagaacac ctcaattgga
    66241 cagtgtactg gattggacga aaaaagaact ggcaagagga catcaaatgt atgtcatctg
    66301 tccgctgatt gaagaatcag aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa
    66361 acttcgtgaa ctatttgcac caaaatatga agttggcttg ttacatggta aaatgaagaa
    66421 tcaggaaaaa gaagtaatca tggaagcctt caaagacaac cagatgcaga tattagtttc
    66481 gactactgta attgaagtag gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga
    66541 tgcggatcga tttggattgg cacagctgca ccaacttcgt ggacgtgttg gacgcggaag
    66601 tgatgcttcc tactgtatct tagttgctaa tcctaaaaat gaactaggtg tggaacggat
    66661 gaaaatcatg acagagacca ccaatggttt tgtactaagc gaaaaagatc tggaattacg
    66721 tggtcctggt gaagtatttg gcttccgtca atctggtctg cctcaatttg cgattgctga
    66781 cttggtgacg gatggaaatg ttttggaggt agccagagaa gaggctgcag ccctttggca
    66841 aataaaggat tggcagatgc ttcctgagta tcagccttta gcgcaaagcc tccaaataga
    66901 aaatcaggat aatcgttatt tcgattagca gactgtgcta tactttatac tgatgacgga
    66961 aaaaggagtg gaaacaatga aaattgccgt agatgcaatg ggcggagatc acgcacctca
    67021 agcaattgta gaaggcgtgg ctttagcgca gcaagatttt ccagaagtag aattcttact
    67081 ttacggaaaa gaagcagaaa tcaagaaata cttaacaaat gaaaaaaaca tcacgattat
    67141 ccatacagac gaaaaaatca atagtgatga tgagccagta aaagcaattc gacgaaaaaa
    67201 gactgcatca atggtccttg ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt
    67261 ttcagcaggg aatacaggcg cgctactagc agcagggttg ttcatcgtag gacgtatcaa
    67321 aaatatcgaa cgccctggct tgatgtctac cttgccagta gtagggaaag aaggtgccgg
    67381 tttcgatatg ctggatcttg gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata
    67441 cggtatttta ggttcttttt atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc
    67501 actcttaaac aacggaacag aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga
    67561 actccttcag aatgaaacaa gcttgaattt tattggaaac gtagaagctc gtgagctact
    67621 caatggtgtg gctgatgtag tggtcacaga tggatttaca ggcaacgctg ttttgaaatc
    67681 tattgaagga acagcaatga atatgatgaa tctattaaaa tctgctattc taaatgaagg
    67741 gatcaaagga aaaatgggcg ctatgctttt aaaagacggc ttacgttctt tgaaagcaga
    67801 aatggattat tccaaacatg gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa
    67861 aactcatgga gcaacaggcc ccgatgctgt tcgctatacg atccgccaaa tccacacaat
    67921 gcttgagaca gatgtagttg gacaattagt cgaacaattt gaaaaaagcg aagaatagta
    67981 tttggatatc tgaagcgatc cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc
    68041 agtaaaatta gccatggtgt aggtaattga caagtgtatg attcttggag gtgaaaaagt
    68101 tgactcgcga agaagtattt aacaaagtag cgaaaattat ttcaaatcat tttgagatag
    68161 ataccgataa agtgacggat gaattgaaca tcaaagatga tttaaaagct gattcaatta
    68221 gtattatgga attcgtttta gagcttgaag atgaattcgg tacggaaatt tcagatgaag
    68281 acgctgaaca aattgaaaca gtcggtggcg cagtagatta tatcagcagc catcttaaat
    68341 aatttcaaat aaaagcaaag aaggataaaa agctgcatgc agctttttat ccttcttttt
    68401 ttaatctttt tgacacgtaa aagtcatttt tctgat
//
LOCUS       DARBDN010000005        61625 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000005 DARBDN010000000
VERSION     DARBDN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.005"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="SCH06_000348"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="SCH06_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HEG1076954.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="SCH06_000349"
     CDS             complement(2944..3378)
                     /locus_tag="SCH06_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076955.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="SCH06_000350"
     CDS             complement(3395..4600)
                     /locus_tag="SCH06_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEG1076956.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="SCH06_000351"
     CDS             5294..5680
                     /locus_tag="SCH06_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEG1076957.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="SCH06_000352"
     CDS             5774..5965
                     /locus_tag="SCH06_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076958.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="SCH06_000353"
     CDS             6479..6811
                     /locus_tag="SCH06_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1076959.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="SCH06_000354"
     CDS             7107..7262
                     /locus_tag="SCH06_000354"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEG1076960.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="SCH06_000355"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="SCH06_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="SCH06_000356"
     CDS             complement(9119..10735)
                     /locus_tag="SCH06_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEG1076961.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="SCH06_000357"
     CDS             10853..11071
                     /locus_tag="SCH06_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076962.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="SCH06_000358"
     CDS             11266..11727
                     /locus_tag="SCH06_000358"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1076963.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="SCH06_000359"
     CDS             complement(11920..12159)
                     /locus_tag="SCH06_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076964.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="SCH06_000360"
     CDS             complement(12183..13706)
                     /locus_tag="SCH06_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEG1076965.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="SCH06_000361"
     CDS             complement(13724..13846)
                     /locus_tag="SCH06_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEG1076966.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="SCH06_000362"
     CDS             complement(13876..14859)
                     /locus_tag="SCH06_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEG1076967.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="SCH06_000363"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="SCH06_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEG1076968.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="SCH06_000364"
     CDS             complement(15053..15430)
                     /locus_tag="SCH06_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1076969.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="SCH06_000365"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="SCH06_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEG1076970.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="SCH06_000366"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="SCH06_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEG1076971.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="SCH06_000367"
     CDS             complement(16448..18214)
                     /locus_tag="SCH06_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1076972.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19927)
                     /locus_tag="SCH06_000368"
                     /pseudo
     CDS             complement(18174..19927)
                     /locus_tag="SCH06_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(20037..20606)
                     /locus_tag="SCH06_000369"
     CDS             complement(20037..20606)
                     /locus_tag="SCH06_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEG1076973.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20624..22039)
                     /locus_tag="SCH06_000370"
     CDS             complement(20624..22039)
                     /locus_tag="SCH06_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEG1076974.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22050..22718)
                     /locus_tag="SCH06_000371"
     CDS             complement(22050..22718)
                     /locus_tag="SCH06_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEG1076975.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22848..23432)
                     /locus_tag="SCH06_000372"
     CDS             complement(22848..23432)
                     /locus_tag="SCH06_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1076976.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23763..23996)
                     /locus_tag="SCH06_000373"
     CDS             complement(23763..23996)
                     /locus_tag="SCH06_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HEG1076977.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24011..24961)
                     /locus_tag="SCH06_000374"
     CDS             complement(24011..24961)
                     /locus_tag="SCH06_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEG1076978.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24958..25800)
                     /locus_tag="SCH06_000375"
     CDS             complement(24958..25800)
                     /locus_tag="SCH06_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEG1076979.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25802..26521)
                     /locus_tag="SCH06_000376"
     CDS             complement(25802..26521)
                     /locus_tag="SCH06_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEG1076980.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27213..27371
                     /locus_tag="SCH06_000377"
     CDS             27213..27371
                     /locus_tag="SCH06_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1076981.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27443..28669
                     /locus_tag="SCH06_000378"
     CDS             27443..28669
                     /locus_tag="SCH06_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1076982.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28757..29149)
                     /gene="rpsI"
                     /locus_tag="SCH06_000379"
     CDS             complement(28757..29149)
                     /gene="rpsI"
                     /locus_tag="SCH06_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEG1076983.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29165..29608)
                     /gene="rplM"
                     /locus_tag="SCH06_000380"
     CDS             complement(29165..29608)
                     /gene="rplM"
                     /locus_tag="SCH06_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEG1076984.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30127..30594)
                     /locus_tag="SCH06_000381"
     CDS             complement(30127..30594)
                     /locus_tag="SCH06_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEG1076985.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30714..32252)
                     /locus_tag="SCH06_000382"
     CDS             complement(30714..32252)
                     /locus_tag="SCH06_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HEG1076986.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32332..33018
                     /locus_tag="SCH06_000383"
     CDS             32332..33018
                     /locus_tag="SCH06_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEG1076987.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33219..33746)
                     /gene="msrA"
                     /locus_tag="SCH06_000384"
     CDS             complement(33219..33746)
                     /gene="msrA"
                     /locus_tag="SCH06_000384"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEG1076988.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33830..34507)
                     /gene="pgmB"
                     /locus_tag="SCH06_000385"
     CDS             complement(33830..34507)
                     /gene="pgmB"
                     /locus_tag="SCH06_000385"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEG1076989.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34504..35634)
                     /locus_tag="SCH06_000386"
     CDS             complement(34504..35634)
                     /locus_tag="SCH06_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEG1076990.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35634..37817)
                     /locus_tag="SCH06_000387"
     CDS             complement(35634..37817)
                     /locus_tag="SCH06_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEG1076991.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37814..38839)
                     /locus_tag="SCH06_000388"
     CDS             complement(37814..38839)
                     /locus_tag="SCH06_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1076992.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38884..39711)
                     /locus_tag="SCH06_000389"
     CDS             complement(38884..39711)
                     /locus_tag="SCH06_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEG1076993.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39708..40775)
                     /locus_tag="SCH06_000390"
     CDS             complement(39708..40775)
                     /locus_tag="SCH06_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HEG1076994.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40801..41637)
                     /locus_tag="SCH06_000391"
     CDS             complement(40801..41637)
                     /locus_tag="SCH06_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1076995.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41634..42503)
                     /locus_tag="SCH06_000392"
     CDS             complement(41634..42503)
                     /locus_tag="SCH06_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1076996.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42573..43856)
                     /locus_tag="SCH06_000393"
     CDS             complement(42573..43856)
                     /locus_tag="SCH06_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEG1076997.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43870..45555)
                     /locus_tag="SCH06_000394"
     CDS             complement(43870..45555)
                     /locus_tag="SCH06_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HEG1076998.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45830..46855
                     /locus_tag="SCH06_000395"
     CDS             45830..46855
                     /locus_tag="SCH06_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1076999.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47450..51124)
                     /gene="rpoC"
                     /locus_tag="SCH06_000396"
     CDS             complement(47450..51124)
                     /gene="rpoC"
                     /locus_tag="SCH06_000396"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEG1077000.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(51182..54799)
                     /gene="rpoB"
                     /locus_tag="SCH06_000397"
     CDS             complement(51182..54799)
                     /gene="rpoB"
                     /locus_tag="SCH06_000397"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEG1077001.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55527..56495
                     /locus_tag="SCH06_000398"
     CDS             55527..56495
                     /locus_tag="SCH06_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1077002.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56513..57418
                     /locus_tag="SCH06_000399"
     CDS             56513..57418
                     /locus_tag="SCH06_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077003.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57415..58221
                     /locus_tag="SCH06_000400"
     CDS             57415..58221
                     /locus_tag="SCH06_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1077004.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58357..59346
                     /locus_tag="SCH06_000401"
     CDS             58357..59346
                     /locus_tag="SCH06_000401"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HEG1077005.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59663..60187)
                     /locus_tag="SCH06_000402"
     CDS             complement(59663..60187)
                     /locus_tag="SCH06_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HEG1077006.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60474..>61625
                     /gene="scm"
                     /locus_tag="SCH06_000403"
     CDS             60474..>61625
                     /gene="scm"
                     /locus_tag="SCH06_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEG1077007.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTS"
BASE COUNT        18701 a        12372 c        10319 g        20233 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctctaaagtt aaccaagcaa
    19741 cagtttgaac cgcataactc ttagctaaat attcatctcc tacaataatt agagactgaa
    19801 gaaatttgta aatactgtaa tatccataga ctgttaatac gacagaaaaa tcagaaaata
    19861 aagtggctaa ccatccgtag tatttcattt tagggacata actaaataat tttttgtata
    19921 ctttcatttt ttcctccccc gcattcaatt tcttctctta ttcgtttaca actgttaatg
    19981 ctttccgtaa tagcgtaaat tagagatgta caaacagata aaaggtaaac tacgttctat
    20041 tttttgtatt tttttaagac ttttcttcca atcaatacac caatcataga taaacttgct
    20101 acaactaaca ctgaaatgat tccccatata cctaccgcat agtggatcat tgcatccatt
    20161 gttgcagcag attgtccttt atctatccaa tcttgacgaa aacgatctgt aaagaaccat
    20221 ataggaatcc actgtccggc agcactgcct aattgcatta gagcccaaga cgcaacttga
    20281 ggaattgctc gatcatatcc aaatacagat agaataatat cagctaagat cgccatacta
    20341 atcgaactga taaaccaagg taagtacgcc ccgcccatta acgtaaaaaa taacaataaa
    20401 acaattgtgt aaatagtaaa aattcctttt ctagggtagt tatagctaat ataaacaaat
    20461 atgattccag ataataatcc aaaaatcccg ggggatatgc tgtgaccaaa cgccccacca
    20521 atactactaa ccattattga aaaaaagtaa attactaggg aaataactgt agctaaacca
    20581 ataaaaatat aatcttttgt tttcatatat attctcctca attctatttc gttatgtcat
    20641 taaaaatctg ttctatcaaa gttgaatctt ctactctaag ttttatatct ttttttattc
    20701 caccattttt taaataaata attctattgc atgttttata aagaaattcc ggatcatgag
    20761 tagctataac tactgcaccc ttttctttta agtctttaat aaggtcagca atcctttcca
    20821 tattaatata atccaaccca cttgtaggtt catcaaatag aaataaatta gtttttgaca
    20881 atgaagctat agaaaccaat aatctttgtt tttctccacc ggataaatca aacggtaatt
    20941 gatctttcat tttataaagt tccatttttt ttaaaatttt ttcttgctga tctttactaa
    21001 ctatttcatt ccccagggct aactcgctcc tcactgattc tgtgaaaaat tggtaatcca
    21061 tttcttgcat tactaaaaac ggcgatgaca aatttttttt attttcgatt atctttcctt
    21121 tggtagggcg aataatcttc atgagtattc ttagtaaggt tgttttcccc acaccgtttt
    21181 tccctaccaa accaataaca tctccaactt tgacatcaaa atttatgtct tttagaatat
    21241 tttcataagt aatttcttca acttttaata catctgcact taccttttcg atatagggaa
    21301 cttcaatcga actattaaaa atgtcaaatt tccttaatgc gttattgttt tcagttttta
    21361 acaactgaat agttgtagtt tttacagttc tatttttaac aaatagaact tgatcaatta
    21421 attctttcaa atagtaaaaa cgatgttcag ctataacaat agtaaatcct ttatttttta
    21481 aatcacaaag taagtcagca agtttcttag tcgctttgaa gtccaaattt gaagacggtt
    21541 catccaatat aattaattta gagtttagcg ataaactaca tccaatagaa attttctgcc
    21601 gttcaccact tgatagcgaa aaaatgtttt tatctaatat atttgaaaga tctaataatt
    21661 cagctaattc attgattctt ttatccatat gctcttttgt aaatccaaag ttttccatcg
    21721 aaaatactaa ctcactcgtt gtatttgttg taaagaattg tcctctagga tcttgactta
    21781 cgtagccaat attttttgat atactttctt gtgttaagga ttgtagcgag ttattttcaa
    21841 ataaaatttc cccaaccaat tttccgtcat aaagtcttgg aataagtcca ttcattaact
    21901 ttaatagtgt ggatttccca ctcccagaag aaccagtaat caatgtaaga ctgccttttt
    21961 ttattgaaaa attaaggtca acaagcgctt gttccttaac atccttatat gaaaaagaaa
    22021 cattgttaaa ttcaaacaat tctttcacct caaatcaaaa tacttaagaa aaaaatagta
    22081 acggaaaaca ggatgatata gtctaataag ctcatgtttg ttttatagta agaacttctt
    22141 ttcacaggag attctatccc ctttgttatt gcattagcgg tcatttcttc agcaatcata
    22201 gttgcacgta taagaacggg aactaacaga aattccaaat attgcagagg ctgaaaaaaa
    22261 gacaagcgaa tgtttctcat ttttaaagat tctttaatca ttcttatttc agaacgataa
    22321 gtcggaaaga atctgatcac tactgtaata cttaacatta tttttttcgg taaatgtatt
    22381 ttttctaaag aggataataa ttcattgcta gtatagacac taaccaacaa ccatgagatc
    22441 attacgaccg gcaacattcg aaatacaata tataaggatg tcgcaaaaaa tatagtaaaa
    22501 aactctatct tgatagcatc aataattttc attactaaaa acagaactga ataaatcaag
    22561 atgaaataaa tacatgtctt tattttacga aacatcaata ctaaaactgt agcaataatg
    22621 aaacacccca cttgaaatat atttcccttt cctaaaaaaa taatgaccgg aaaaaaaata
    22681 tttaaagtaa tcaaggttaa cggattgatt tttgacactc tttcacctcc aaaaaataag
    22741 atcgcactgt tatcttaagc tgataaaaat gcaccgttat tcagataaca gtgcgatctt
    22801 atcaaaaagc ataactgaga acaattctca atgcaagctt tttttaatta actcagtaat
    22861 tcaatccacc caggaacaga aaattgatac aatcttctgg ttaatagcat agtcttttct
    22921 tttgaatagc tatgcttcaa tatatcatag aatgtagcgt agaatgagta aatgtagaag
    22981 tggatttctt cttcattaaa gactaaattt tgattgatca ttccgatagt ctttaactta
    23041 tctagacaac agactgtctt tttcgtcaca aatgatgtaa ttttttcaac aatatcttga
    23101 tatttggttc cagctgattg gaataaaatc aaatcgaata tacgtttatt ctcaaaaata
    23161 taattaataa atggatctaa ttcattgaag ttctctctcc aacttttctc tatatctata
    23221 ttttctaagt ttaagaggta tttggtaaac tcttcattat acatattaat aagcgcatta
    23281 atatgcggct gaataatttc ttcaaataac gcttccttag aagtaaaatg tttataaaaa
    23341 gcacccgtag ttacgcctgc ggtcaggcac agttgcctta tcttagtttg ctgaaatcct
    23401 tctttttcaa aatggcttag tccactttct attaactttt ggtgagttat aatataatct
    23461 ctggtttcta tgggtacttc ctcctaataa gatgaattaa ctttattatc ttacacagga
    23521 cttgaagttt caatcgttaa cgtttattac tgaactcatt ccttagagct aaactaatga
    23581 gaaagagcag aataactgat acaaaaagca atcctacaag aattaataga ctcatctaaa
    23641 tcattcacct tttctaaaat aatccgagaa agatttaaaa aaattatatc cagctattag
    23701 gataagtcct atcataatca ctccaatagc cattttctta tcctccctaa aaataaagtc
    23761 ttttacttaa aacctttttt gtaatcgtca ataaattttt tccctttatc agttaattga
    23821 aatcctatat ctaaatagtc ctcatatcta agtttagcca gcatctcact tacagatgct
    23881 ggactaacac ttagaacttt tgctaaatca ttatttttta atttcttttt tctttttgat
    23941 aattcctgaa ttgctagtaa ataaattagt atagtagtcg ttttaatttg taccatacct
    24001 accctccaaa ttatttcgaa aggccttcag caattttatc caggttccat ttcatcatcg
    24061 catagtaact atcaccatct tgtccttttt ctgcaattga atcagtaaaa atcgttgaat
    24121 agataggaat attggtatct tttgatactg ttttcattgg tctatcatcc acactgcttt
    24181 ctacgaataa ggagggaact tttgttgtgc gtaatttttc aactaagtgt tttatttgat
    24241 ctggtgttcc ttcttcttca gtgttgattt cccaaatgta agcagaaggc acattatacg
    24301 ctttcgagaa atatttaaag catccttcac ttgtaacaat cattttttta tcattcggaa
    24361 ttgaagcaaa tttagattta gcttctttgt ctagagaatc caatttttca atatacttat
    24421 ctagattttc tttatagaat tttttattat caggatcttt ttccgctaac tgtttttcaa
    24481 tatttttagc gtaaataata ccgttttcta aatttaacca agcatgagga tcttccttcc
    24541 ctttctcact ctgaccctct aagtaaataa catctatgcc atcacttgct gcaaaatagt
    24601 ctttgttttc ctctttgttc gcatttttaa ctaattttgt aaaccaagca tttcctccag
    24661 tttccaagtt aacaccgtta taaaaaatca aatctgcttt tgaagttttt tgaacatctt
    24721 caggcaaagg ttcatattcg tggggatctt tcccaatagg tacgatactg tgtaaatcaa
    24781 ttttatcttt tgctatattt tcggtaatat ctgctaaaat cgaattagta actactactt
    24841 ttaatttttc gttcgaagcc actttatctt tgtctttact atttattgaa catgccccga
    24901 atataaaaag agcaatcaaa atccccagac ttcccagtac tgctttccat tttctcatca
    24961 taacgatctc tccttctttc ttaaaaattt ttgttttggt gagattagaa aactaattac
    25021 aaataagaat gccgctgtta aaacaatact tgatcctgct gctatgttaa aactataacc
    25081 aataaacaat ccaagcaatg atgaacttgc tccgactgtt gcagaaataa atatcatagt
    25141 tttcaagcta tttgcatata aatatgctgt agctgctggt gtaattaaca ttgcaacaat
    25201 taatatagtt cccacacttt gcatagctgt tactgctact aaagttaata gaaccatcaa
    25261 tagataatga taaaaactga cattcatccc tattgctttt gccattaatg gatcaaaaga
    25321 agtgattaat aattctttaa aaaatagaac tactataacc aacactaaaa ccgaaacgcc
    25381 aattgtaatc cacttatcaa tatcttgtac agctaaaata tttccaaata aaatatgaaa
    25441 taaatccgtt gagctatttg caactcctat aaggataact cctagtgcta aaaaagaact
    25501 gaaagtaata ccaattgctg tatctccttt tattacacta ttgcttttta taaaagtaat
    25561 aatgatagaa gctaatagac caaatacaat cgcaccaata aaaaaattaa tacctaaaat
    25621 ataagaaatt gctactcctg gcaaaacagc atgagaaata gcatcaccca taagagacat
    25681 tcctcttaaa ataataaaac aacctactgt tccagaaaca atccctataa ctacagatgt
    25741 aattagagca ttctgtaaaa agtgaaagtc atacagacca ttaataaaat tttgaagcat
    25801 attattcccc ctctccaata aatatagtat ctccataggc tttttttaaa ttttcttcat
    25861 taaatacaga ttctacactt ccgtgagcaa ttagatttcg attcaaaaga ataatattat
    25921 caaaatactt ctttaccttg cttaaatcat gatgcacaat tagcactgtt tttccctgat
    25981 gtttcaattt ttttaacgta tccataatta ttcgttcact aactaagtct atccctacaa
    26041 atggttcatc taaaaatatg aaatccgcat tttgagcaag acatcttgct aaaagtacac
    26101 gttgaaattg tcctccagat aattctccta tttgatgatt agaatatttt cccatatcga
    26161 ccttttccaa agcctttgaa actctttgcc attctgcatt tttaattctt tgaaaaactt
    26221 tcattccggc atatgttccc atagatacac attcttttac ttttattgga aaagtaaaat
    26281 caatatcagc tttttgctct acatatgcaa tcttcaccag ttttttattg atatcttcat
    26341 tattaatgga gacctctccc tgatgaggga taatatttaa cattgcttta agcaatgtgg
    26401 attttccagc accatttgga ccaataatac ctgttaaagc accttcttgt atttttaaag
    26461 aaatctcgtt caatgctaaa aaatcgttat aacaaacatt aagctttttc acttctaaca
    26521 taactttctc cttctaaatg ataatgatta tcacgatcat atggtataca aaaattatat
    26581 tttagtcaac cctaaatttt atagtttaga tttttttctg ttgctgaaga ttagaatgac
    26641 aaaactattt gaaactacgc gtatagtaag tagctttcaa aatatataaa aaaggagcgt
    26701 tctcaaatga gaacatgctc ctaaaactac tttattggcg tatggaaaaa ttatacttga
    26761 agtggatagc gggttgaata agttgataag catcaaaaca tttataaaaa ttattcaaga
    26821 ctatgtctgt tccatataca aatatgaaaa tcagtaaact ccatttaact tttttcgtag
    26881 tgtgtctttt tatacatgtt tatcgttatt aatagtgaat aggaaaaaaa ctatttttga
    26941 tcattgacaa ttaaatacaa tttttgaata acgatccctg ctattcgagc tagaaactca
    27001 agtacgccat gacctgatta gcgacaaata cttagagatt tctttttgtt ctgggaaaac
    27061 aaaatgccat gacaatagca gcaaataatg atacttccgt aaggctcgcc gtaaactggg
    27121 gagaggtgaa attcctatgt gcttacccaa agcaattcaa aaatttcata actactattt
    27181 taggagatga ttttatagaa tccagagtct acctgaataa aaaacaaacc tgtgcatttc
    27241 taggaatcga taataatact ctagataagt ggattcgtat atataatttc ccagtaataa
    27301 gagttggtgg tgtagttcgc tttgacgtag aagatattaa agactttatg aatacattta
    27361 aaataacttg aaattttctt ctcgccgcat atactaaaat tagtgaaata tactgcctta
    27421 ctttttttaa ggagtgagga ttttgcctac aaagctttca aatgggaaat ataaaactaa
    27481 tctgagatat ccaaaaaggt ttaaagaaat aacaggaatt gcatcagaaa agtatcaaaa
    27541 aacatttcca aataggcaat tggcgattaa agccgaaaat gatatgaaga agaaaataga
    27601 aaaagttttg agagaggaga atgcaaactc attagaatta aaaggaaaaa taacgtttaa
    27661 aaaattttac gaatctaaat ggcttcctag atatgaatta ggtcaaacaa ttagatcaaa
    27721 caggcctcct agtgatataa ccattagtaa tacaaaagat atatttcggt tgcatatttt
    27781 acctatgttt ggtgaatacg caatgaatta tctaaatatc aatactgaga taatatcaga
    27841 tgaattaacc aaaaaatcga aagaatatgc aaatataaaa atcataaaag gatatgttcg
    27901 ttccatgttc gatattgcag aaatactaaa ttatatcgaa tttaatcgaa ctactaaaat
    27961 tattcaaagt atcactgcac ctaaaaaaaa tgctttagaa gaaaaaagaa tacaagaagg
    28021 taagcaagca ctatcatcaa aagaacttac taattggata gaagcagtaa atgatgattt
    28081 taataatcat ttacttactt ttcatgatta cacacttttt atgattaccc tgtatcttgg
    28141 tgatagaaaa agtgagactt acgctttgca atggaaatat attgattttg aaaaacaaac
    28201 ggtccgtctt aaacatactt tagataaata tcaaagaaaa aagtttacaa aaggtcgaaa
    28261 agataccgtc attcaagtac cagaagttgt aatgacattg ctaagtgaat ggaaatcggt
    28321 acaagctgat caattgttga aattaaaaat taagcaaacg ttagatcagt atctctttac
    28381 ttatactaaa ccatctggag aagtaaattg tcctgttcat gccgattacc taaactatcg
    28441 aatcaattca attaaaagaa ggcatcctga cttagttcat ttatctccac acaaactccg
    28501 tcatacttat gcaactatag ctagacaagg tggagcagat atgaatcaaa tttcaaatgc
    28561 tttaacacac tcagatattt ctacaacaaa gatatatgtg aacacaccag atatagttga
    28621 taaggctgtt tttgaagctt ttcagagagg attgaataag tgtgattgat atgtgttctt
    28681 aaatgtgttc ttaaaaacaa aagaagcact ttccaaataa ttgaaaagtg ccagaaacgt
    28741 tgatatataa aggatattaa cgttttgaga attgtgaagc tttacgtgct ttcttaagac
    28801 ctggtttttt acgttcgacc atacgtgcgt cacgagtaag taagccagca cgtttaagag
    28861 ctaaacggaa gtcaggatca acttctagca atgcacgagc gataccatga cggatagctc
    28921 ctgattgtcc agcgtatcct ccgccgttta cgttaacaaa tacgtcatat gcgccttttg
    28981 tttcagtaac agcgaaaggt tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt
    29041 cttcaacatc ttttttattt acagtaattt tgccagttcc tggtactaga cgtacgcgag
    29101 caactgcgtt tttacgacgg cctgtgccga tatattgaac ttgtgccaat gaaattccct
    29161 cctattagat taagtttgtg atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt
    29221 ctgctccacc gtatacgttc aattttgtaa attgtttgcg gcctaaagtg tttttaggaa
    29281 gcataccttt tacagaagtt tcgatcaaac gacgagaatt tttagcacgc aattcgccag
    29341 cagtgattga tttcaatcct cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg
    29401 cttttttacc tgttaatttc actttgtctg cattgatgac gatgacgaaa tcgccagtat
    29461 ccaaatgagg tgtgaaagtt ggtttatttt taccacgtag tacagatgca acaactgttg
    29521 aaagacgtcc caatggaaca tcagttgcgt ctactacata ccatttacgt tctacttcgc
    29581 ctggtttggc catatatgtt gtacgcacgt tattttcctc caatttaagt tctgatgttt
    29641 gacatacact tcgagtttcc ggggctcttt gtggggcaaa caataccatt taacatatta
    29701 cccgctaatc tagtcaatgt caacgttttt ctgcttgatt gaaaaattta tatgaaactt
    29761 tacttctttt ctttctttta tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag
    29821 aggctgtgac aaaagtcttg tcacaacccc ttattttgaa taaacggtgt tctcctgcca
    29881 actcctcggt cacaagtcac aatatccata aaacataaga agctgttttt taaaattgtt
    29941 tcttgtgact cggagctgaa cggcaggctt acaacctctt ggtaaacggt gttcaatcag
    30001 ctgaccctcg gtattagctc aaaaaacggc aaaatatgag gaactatttt gacgtttgtt
    30061 tctctaatac tcaggtcaaa acgctgattt cacaacctct ttttcggtca agttcaacaa
    30121 cagtttttac gcgtcgatct ctggcgcttt gcccaaatga gcttggatca tccagatacg
    30181 tttttctgtg gctgttttga attcgataaa gatatcttgt gttggatcgt cgccttcttc
    30241 tccagaaact tcgattcctt tttggtaaag atctgctaga taacgatagc ctgcaacaag
    30301 tgtttccaaa cgttctggaa tagtacgatc ccagcggcca atttcatcag ggatttttgt
    30361 gttatctgca aattcacgca atgtagaata aggtgaaccg tctaatgtga tcaagcgttc
    30421 ggatacttca tctaactgag cgttcaaatc atccatgaac tcatccatca ttgggtgcaa
    30481 tgtaaggaaa cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa cagacatttg
    30541 gcttagatct gcaactaatt gatttaatac ttctttggtt tgttggaatt tcatctttct
    30601 tgcctcctaa cattttctta cacttaaaat aatagtagac tttcaatgaa aagtacaaca
    30661 aaatcattta cctgagaacg attttcagtt cgctttttta tccgtaaagc caatcatttt
    30721 tcagaatcag ctaattcttc tcgcagttga gcaaattgct gataagtctg tgctaaatgc
    30781 ttttgtgtcg aaacaaataa tggatagatt ttctgatatt ttttatgatc agtttcttgt
    30841 actccaactt gctctttcaa ttctatcaat tcctgtgctt cactgatact ttggatcttt
    30901 ccgatgcttc tccagcctaa aatcacagct cctaatgcgg atgcttctgt gacagtaggg
    30961 aaaacaagcg ggtaacccag tacatcagcc atcatctgac gaaaaatcgg agattgagca
    31021 aacccgcctg tagcacggat ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc
    31081 cgataaaggt tgagacagat cccttctaga atcgccttca tcatttcttt ttctgtatgt
    31141 tgccgctgta aaccgataaa actgccaaac gcatctgcgt cccaaagcgg tgctcgctca
    31201 ccaagtaaat agggatgaaa aatcagacca ttggcacccg ctggcacaaa agcgatagcc
    31261 gaaagcagtg catcatatgg attttctcct ttttctttag cagattgaac gacttcctgt
    31321 aaaaatgtat gccctgccca atcaaagatg ccagcaccat tgctagtcgc tcctcccact
    31381 acccaatgtt tctgatccag aacataacaa aacgtctcca tttctggatg gaactgaggc
    31441 tgagtagtaa taaaacgaag tgctccgctc gttcctacgg tcaaagcggc gatcgtatca
    31501 ccaaaagcac ctaaccctag attagaaagc ggcccgtctg cccctcccaa aacaaatgat
    31561 atatcatttg gcaaacctag ttctgctgct gtttttgatg gtagacctgt tacttgatag
    31621 gtggaaggaa agacttgcgg caattgctct attcgaatgt tcaagtagtc aagcacttct
    31681 tctgcccatt ggaattcatg gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg
    31741 ctgatcagtt cgccaaacaa tctataaaag atatagtctt tgataccgac aaaataagca
    31801 gtttttttga ataattcagg ttggctgttt tgcagccact tgattttgtt caatggtgtc
    31861 attggatgaa tcggcgtccc agtctgccga taaaattctt tgccaagcac ggtatatttc
    31921 agtttttctg cttcgtccgc tgctcggtta tctgcccaag tgatcattcg agataacggt
    31981 gttttctctt catccaacaa tatcaggcca tgcatcgcag aggagaagga gacaaattga
    32041 atgattgtgt ctgaaggcaa ctgtttaatt acttctttta taacggtgca gacaccttga
    32101 aagatcaatt cctgatcttg ttctgccatc ccttgtgttt cttggatcaa agggtagcga
    32161 aaataagcgg atgctgcttc ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg
    32221 gttccgatat ctaatccgat tgaaacgttc attttttcac ctcaaatttt atgtatgtac
    32281 aaaaatttag tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt
    32341 tattttatca ttggttgctg tatcggatca tttttatgtt taaccgccca gcggattccg
    32401 ttaggtcact ctattattta tcctagatct cattgtgtca aatgctgtcg ttcgctttct
    32461 tggtatgaat tgattccgat tctctcgatc atcgtccaac gatttcgctg ccgctattgc
    32521 aggtgtcggt tgcccttcta ctatttgttg gcagaagcct tatgtggtgg tctttttgcc
    32581 tggttcttta ctttttcttc cgcaagaaat ttttcgacgt tcatatggat gctttcggct
    32641 ttgctatttt cgttgatgga tttattttac ttcatggtcc attctcacac gctattctgt
    32701 tcttgggcaa ttttatggat tttttggttg caggccggcg tcttccaatg gcaaagtgtg
    32761 ctgttaacgt ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta tctcggagct
    32821 ggcgatactc tgttgatgct ttcttggagt ggtggcttgt ctctagaaga gttgcttcag
    32881 atcttgtttc ttgctagtct gtttggaata tccgtttttt ctgtttactt tatctgtcat
    32941 aaaaaaaagt tggaaaagct gcctttcatt ccttttttga gcagtgcgtt gctgattgtc
    33001 cttcatctta ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc tctgatatat
    33061 agtgttctct taccaaatcc ttgtgacttg gagctaggcg acaggttcac aacctctcca
    33121 ctaaatggtg ttcaatcagc tgaccctcag tattagctca aaatgctggt tttacaacct
    33181 ctgatatacg gtgttccata agtagctttt tcggcttctt atttcttgac gccccaatgt
    33241 cgacgaagga aacctgcacg tccagaacct tctcgataaa gattgtaatg gagcttgttt
    33301 ttcttgtaat aatcctgatg gtaatcttct gcaggataaa attcgcttct tggttcgatt
    33361 tttgtcacga ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct
    33421 gcaatatttc gttcttcttc atcattatag tagatcactg gacgataaga atcaccgcga
    33481 tcagcgaact gtcctaatgc gtcagtcgga tcggtttgct gccaatagat ttccaccaac
    33541 tgatcataag aaataacttc tggatcatat tcgatctcta ctgcttctgt atgccctgtt
    33601 gtgcctgttg ttacttgttc ataagttgga tttggtacat gcccgccagt ataaccggat
    33661 gtcacagaaa tgatccctgg ctgctcttca aatggtttga ccatacacca aaagcatccg
    33721 cctgcgaaaa ctgctttttt tgtcatataa aatccccctt ttttctcatc ataccttgat
    33781 ttccaaaagg aggataacgt tttgcttgtg acagaaaaaa cggaaactat tatatacgtg
    33841 atacggcttc tgataaatgc caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa
    33901 tcacatattc agcagaagga agatttatgt tttcacctat tcccaataca tgcatgttac
    33961 cagccaaagc tgcttgacaa ccagcttctg aatcttcaat gaccaagcat gcatttggcg
    34021 gtacattcaa ttgctgtgct cctttgagaa aaacttctgg atcaggtttt gcttttgata
    34081 cttgcgtgcc gtcaataagg acatcaaaat aacttgtcaa attcgttttt tctaaaatga
    34141 ggcgtgcatt tttgcttgct gatcccaatc cgatcttgat gtttgttttt ttcaagtact
    34201 caagaacagc tattgcacca ggcaaaacgg atgtttcatc cattttttga atcgcttgaa
    34261 gatatagatt gtttttttgc tcagcaaagg ctgatttctc tttttctgag aatttctgtt
    34321 ccatttttcc aaatgacagc aatcgctcta gtgactcggt tctggatatt cctttcagtt
    34381 gctcgttttc tttctcagtg aatggaatgg acagctggtt agctaaaacc agccacgctt
    34441 cgtaatgata acgagctgtg tctacaagaa cgccatctaa atcgaatagt gctgctttga
    34501 ttttcatcga ttacctcctt gaaaatgaac gacttgaagt aaagatgcga tgtttttagc
    34561 tgtgcgatga agattatcag tggcttgctg taaagcttct tgtaaaggca cagctgcagg
    34621 aaggatcgga aaaacggccg aaatgccaac atctgctgct ttttcgcttc ctttaccaac
    34681 acttccgcaa atagctatca caggaacgcc ctctggtact cttctagcaa tcccaactgg
    34741 cgcttttcct tttagacttt gtccatctag acgtccttcg cctacgatta cgaggtctgc
    34801 ttgctgtacc cgtttatcga actccagtaa atccaatacg tagtcgatgc cagagactat
    34861 tttccctgaa gcaaatgcta acagtcctgc acccattcca ccaccagcac tactgcccga
    34921 tgcctcgatt acttgagggg caaatctcat ataaaaatca tgcatggctt ggtcagccac
    34981 tgctaattca ttttctttca agcctttttg tggtccgaaa acaaaagaag cgccttcttt
    35041 tccgcataaa agattagtaa catcagtaat gacagtgatt ttggctttaa tcagctcaat
    35101 aggcacgttc gttttatcaa ctgtagcaat tttacctaga ttttctccca gtgcttctac
    35161 tttttgatta tcttgatcgt aaaaagcata acctagacct tctgccatgc cgatgccgcc
    35221 atcgttggta ctacttccgc caacgccgat gatgatgtgt cgaacacctt gttgcaacaa
    35281 ttgtcgtatc agttctccta ctcctcgcgt ggataaccta agtggctgtt gttggtttag
    35341 tgggacatct ttcaatccga cgatttctgc catttcaaaa atcgcagttt gaccgtctga
    35401 agcgtactgg atttctttgt ttttgccaaa tgcattagta acgactgctg tttgccgctt
    35461 caaccttaaa ctgtctgcta atgatgaaac cgttccttct cctccatcgc ctataggtag
    35521 cagatcatat tcagcctgaa caaaaacttc ttgaaaacct gattgaatgg cttgtgctgc
    35581 ctctaaggct gtcagacttt ctttgaaaga atctggcgca atcagaatac gcattatttt
    35641 cccctccgtt ccaagatcag ttctttttcc agctggtatt ggtctccatt gacaaaaata
    35701 ggtaatgttt ctttcgtctc tttttttatt actatttgtt tttttgtcaa aacaaatagc
    35761 aacctgtgat ttttccaaat aaaaggaaaa gaaatttttt cccatgctga aggaagtctt
    35821 ggagaaatag aaagagttcc attcgttact gtaatacctg aaaaaccaaa tataactgct
    35881 agccatagtg ctcctaatga agcagcatga attccgtcat ctgatgaatg cggatctggt
    35941 cctaaatcaa tcaggcacgc ttcttggaat aaatgatacg cccattccat ttcttggata
    36001 cggcaagcct ctatggcgtg aatcgcttta ctcaacgatg agtcgtggat tgttttgttt
    36061 tcatagtaat gcaaattctt agaaacgatt ggttgagaaa aatactcagg taataagtat
    36121 aacagcatga caagatctgc ttgcttgctg acttggagtt catttacttc gctacgggca
    36181 taatcaagta aaatagactg gctgccagga cgttctttgt aagtggtcaa atcaataact
    36241 ggcttactga gatacgtgtc atcttgcgga atcagctgtt ctttgttagg cactggcaaa
    36301 tataacttat ctaaaaaatt ttgacattct ttcaaaaaaa gcggatcgcc agcttgatat
    36361 ttaacagcta aggccacatt ataatgcgcc agatagttcg tatatgcatt attgtcgata
    36421 tattctgtgt attcatctgg accaatgact ctgtgtatct ctaaatgatc atcgactttt
    36481 acagctctgc tcagccaaaa agctgctgtt tcatgaatga gcgtttttcc ctttgtttct
    36541 aaaaacgatt gatcctctgt tgcttggaca tactcttgaa cggcataagc aaggtctgca
    36601 ctgatatgat gttctgcggc agctgaagca acttcttgtc ttgttccggt tttgatattc
    36661 aatgcagcaa atttgggtgt ctcttcctga ccagtgtgtg cgctttccca tgggaaaagt
    36721 gcaccttgat agtgataatc tcttgctttt tgccgtgcgc cttctaatcg atcataacgg
    36781 tacagcagca aattctttgc tacttcagga aactgatata aaaagaaagg caggataaaa
    36841 atttccgtat cccagaaaac atgcccttta taaccttcgc cagttagtcc cttcgcccct
    36901 acactaacac ttggatcatt gcggggagtc ataatctgta aatggtaagc agcgaagtcc
    36961 atcgctaact gatcgaaaga agaatcgcct tggatcgtta tccgatgctg atgccaaaaa
    37021 tctgtccaat aagacatcga ctgctctaaa atttctgtat aactaacgct tttctgggct
    37081 tgggcaatac ttttcttaaa cgggtctgtt tgctgaagag aggtagagag cacgatgatc
    37141 ttctccagcg taaaggacgt attttttctg atcttttctg aaaaggaagc ggtgatccgg
    37201 cgattttttg cttggaatac acctgcttta ttgaatttag ctgcaatccc aatatcaatt
    37261 ttactttctg ttgtctggta ggatgcactg atcaaatcgt caccaaatac tcgcagttct
    37321 ttttcaacca actgctgtgt accaaaattg gtttgctgtc catcgatacc cgttttcaca
    37381 tctacttggc agtcttcggt caacggcttg atgaccactt tcagggctgc ctgatggaga
    37441 ttattttgat cagcaacacg acaagtaatg acttccactt tttttccttg agcagtttca
    37501 atgagcgcat agcgtttaag ctctcccatt tctaaatcta gtgcccgctc gtatgcaaga
    37561 actttcatcg tctcaagaga aaaatgttca ccgtcgattt ttatttccca tctgatgaca
    37621 tctgggagat tcactaactc ggctgattct gctcctaaag gtcggttata tacaccagct
    37681 gcaaacattc cccttacttg attccgatag tcttcctcct ggcttcctct gataccaaaa
    37741 aatccatttc caatggtcat ctgactcgca tacttattga tatactctaa atcaaactgt
    37801 ttttcttcta ctttcataag gtaataactt ctcctgtttc tgccgaacga tataaatttt
    37861 ccaccagatt ctggatgaca tatccttgcc agccatctgc aatcatctga gtctggtcac
    37921 cgagcgcccg attcacaaaa tgagccatac ttagttcatg tgggtcatta actggcgtgg
    37981 tcttttgtaa ggaaaccagc tttccatcta catcttcgaa tagttcgcct ggatacagat
    38041 tagcacctgc ctgatcgcca caaaaagcca cattcagttt gtcttctctg atattcaaag
    38101 caaacgaagt attcagttgg atgatcttgc cgttttctaa ttccagtgtg ccaaaaattg
    38161 catcttctac tgtgaatttg cttggatccc atttcccgaa tttccctgaa ttttttttcg
    38221 taccaatttt ttggaagctg tacgcccgaa cgctttttac tttaggaaat ccagtaatat
    38281 acatcgctgt atcaagcatg tgaatgccat aatcgatcaa aggcccgcct ccttgaagtt
    38341 ctttgtcgat aaacgttccc cagcctggaa caccagaccg acgaagcgca ttcgcttcta
    38401 cgtaataaat atccccgaga acatcaagat gattcttgat cattgttgct tcgtcagaaa
    38461 aacgatgctg gaatccataa gccaaaatct gcccgttttt atcggctgtc tctgccatct
    38521 ttcttgcttg atcagctgtc atagctggtg gtttctcgca catcactgaa gcattagctt
    38581 cgagggcagc caatacatgt tcgaagtgaa agcgattggg tgtacagaca ctcacgatat
    38641 cgggagaaat ctcattcagc atttgtgtaa ctgatgtata cgcatgagaa aatcctgtac
    38701 gtcggcaaaa gtcttctgct cgctggctga ctggatcaac cacagcggcc aattctaaga
    38761 catctgatct tttttgataa taagcagcat gtactttttc tgctacttgt ccagcgccta
    38821 tgattgctac tttcttcatt tatttctctc tcctttgctt atttacttat tgttattctt
    38881 tctctattct ttctctaaat catttaaatg acgcgctgtt tccagacagt ttttcaagta
    38941 ttgcaatgat tcctgataaa ttttcacttc attttctcct cgcaaacgac attcatatac
    39001 catataacct tcatactcat tttgaagtag cgtttgaaaa tggcgagtaa aatcaattgc
    39061 gccagatcct ggttggtagc gatgattatc tgctaaatgg atatgaccca catactcttt
    39121 ttgcgtagtc aatgcttttg aaatatcatc ttcttcaata ttcatatgat aaaaatcagc
    39181 gatgatctgc acatgtttca attgattaga gtcaatgtaa tgacgcgcat ccgctaacaa
    39241 attgatcata tggtcttggt atcggttcaa aggctccaaa taaataaccg tacctgtttc
    39301 ttcggctact ttatctaaat aacgaagtga ttcgctgact gctttatagt ctccttcttt
    39361 gcttcggggt gaaaccatcg gcggtaatcg ataagtgaac attccccaag ctgctgggat
    39421 aacgattcct ttgcctccaa cctcgcttag tgcacgcaaa atctcagcaa tttgacgtac
    39481 accattaaga cgccgttctt cgataaagtc accgatccac ccatcgtagc cgttacaagc
    39541 tgtcactact gggatccctg tttctttgat tgcctgtttg actgtgtcga tattttctat
    39601 taacaactta ccgtcgattt cgtattcttc aaatccacag tctttgataa atctaaattt
    39661 ttctaaaatg tctcttggga aaaatgcttg atcttgcgta ccgaatttca ttgttctcct
    39721 cctcggactt gaacgcccat tttgatactt tcttctgggt gctggtctac ataacgcatg
    39781 taagcttctg cgctttctgc aaatggcaca actggatcaa tgatttcttc acaatccaag
    39841 taaccgttca tcaataattc ccaacatgtg tcctcgattc gtttacggtt ccatcttggg
    39901 taatctgggt ttggttcact agatgctcga gcaaagacga tttttgcatt attgaaatgt
    39961 gcttcgcgac caagattaaa cccagctgga aaaggtttag caaaggcaac ataagaaatg
    40021 atcccgccat agccgatccc tattaaagaa gcttgtaatg cggcagcact gccactcgtt
    40081 tcaataactg aatctactcc acgtttatct gtcaattcct ttagacgaaa accgacatct
    40141 gctttcatag gatctagcgt gtaatcggca ccgtgttttt ctgctaattc tctacgctgc
    40201 gctatgggat cgatcccaac gatggtagta gcacctgctt ttttagctaa ttgaatcgca
    40261 atttgcccga tagcgcctaa accgaagatt gctacagcat cacctgctcg aacatgtgct
    40321 tcccggatac cacctaaagc gaattgagca ggatcgtaac atactgcatt tttccattga
    40381 tccaaccgat caagtttacg tagtttataa ttatcaacac cgtttgtaat cagcgtttca
    40441 cgaatgggtc cataagtgca gactaactct cctttttgat actctgtcac caaactgccc
    40501 gtttcttcga tcgtaccgac aatcatattt cctaattgaa attcgccaaa taccacaccg
    40561 cgttggcttc cttcttctct tggcaagaat aggcgccatt cttctgaaaa ttcttcatcg
    40621 ataaatggac ttaatcctct aaagtcgaca atttctgttc ctggttttgg agtagcgaaa
    40681 attactcgga tacgtacttc gttcttttcg atctcacggt cttcgtaatc tttgaatccg
    40741 gctattcttg gttctaatgc aactaatttt ttcatctttt ctttcctctt tcttttcttt
    40801 ttatcctttt acgccgcctt cgactaaatc acctttaata aatcgttcag ataacgcata
    40861 cataatgatg actggtaaag cggtcaccaa tgaagcggcc atcattcgtc cccaaatgta
    40921 gtctggtgta ctgaataatg tgttcaaacc gattggtaaa gtaaattttt cggaggtcga
    40981 caggaaaatc gaagcaaata aataatcatt ccacgaaacc ataaagcaat aaacgaagac
    41041 agaaatgatt ccagaaatag ccaatggtat aatgatccga ataatgatct ggatccggct
    41101 aagaccatcg atcattgctg cttcttcaat atcagtcgga atcgtgtcaa aataactttt
    41161 tagcatgaat atcgcagtag gaagtgtttg aacgaccatc gtgataatca gtgctgtatt
    41221 ggtatcatac aaacctagac cggaaatgat tttaaataat ggaacaacga tcaaaatacc
    41281 ggaaaacata taaacggtgt aaaagctagc attgattttc gagcgagctt tgaagcgtag
    41341 ttttgacaaa gcgtatgccc cgctgatccc aatcactact gcagttacgg aggctatcaa
    41401 ggagatcact aaactatttt tgaaatacat gatgaatgga aaaatctcag cattgaaaat
    41461 atcctgataa tgttcaaaag tccattcttt cggaaaaata gtttgtgtcg ttgcaattgc
    41521 ttcttgtgaa tccttgaatg atgtcatcag catgatcaaa aatggaaaca aattgacagc
    41581 taatagcaac aaaatcgtcg cgtaaaataa gattttcctg ctctttttat ttttcatttc
    41641 aagtccacct tctttcgtga gagcaagacg accgctgcaa taatgatgaa caatagaatc
    41701 gatatagctg ctgcttttcc aagatcattg aacgcaaagg ctgtctgata caaataaacg
    41761 cctaagatat tgactttatt cgtcagtaga tagacatctg taaacatata gaacatccag
    41821 atagatcgta aaacaatcac agttgctagt actggtttga ttgccggcag tgtcacgatc
    41881 ttgaacttct gccaagcatt tgcaccgtcc atttcagctg cttcataaag cgttttgtcg
    41941 actgtttgca aaatagccaa aaatgaaata aacgcatacg gatagtatct ccagatagca
    42001 aacaaaacga ccataaagaa gctagcaact ggctggtcga accacagcgg tgcttcgttg
    42061 aaaagctgca acctatctac taacagatca ttgacgattc cataactatt attgaacata
    42121 tatttccaag caaaaatcaa agaaatagat ggcgtaacat aacttaataa aatcagtgaa
    42181 cgcaccgttt tcctaaatct gaacttgcgg ttaagcaaaa tagctacggc taatcctaaa
    42241 gctgtactgc ctgctacaac taagaatgtg taagcaactg ttaaacctaa agaacgataa
    42301 aattcactat cacttaaaat ttcaagataa ttgcttaatc cgataaaaac ggcgtctgag
    42361 ttaggattca gcggcatatc gaaaaaactg atctgaatat tggaaagcat tggaatcagc
    42421 actaaaacag ctaataaaag catgcttggt gctaaaagtc ccatggctaa ttttaagtca
    42481 gaatgtttcc ttggacgatt cattgaaacc tccccctgat aatctgccaa tagctatcta
    42541 cttttttcga acaccattgg cagaacttct tgttatttcg tatttttttg tgcgtcagct
    42601 aaagcttgat cgacatcttc gtttccgaca gttacttggt tcactgcttt tccgatcaca
    42661 cctgagcttg tgatatctcc cattttcgtg aaattctttt ccccgactag tccaaagact
    42721 tgtacttcat caaaagcact agcaatctca gatggcagct cgccaaaaga cttgatgact
    42781 tcattttctt tgtaaccatc cagttcgact acttgtttat tcactggttg agcaccacca
    42841 ggagacatca agacccactt ttccatgttt ttcggttgag ataagaaagc tgtgaatgct
    42901 tcagcagcct ctttttgttt ctcgtctaga ccagaagaaa tcgtcaatcc agatactgtg
    42961 ccatagacag cttgatcttt ttgtgttggg atagcaaaac cgatattttc tgagttcccc
    43021 gcttcataaa cagaaggcaa aatgtaagtt gaatagattg ccattggtgc tgttccattc
    43081 atgaaagcat ctttgatttc tgtcacatca ttagagcctg gcatcgtgta ttgggataag
    43141 ttttgataaa acgacaatgc ttctctcatc ttttccgtat cgatcgttac ctcgccttca
    43201 tcatccaaaa catttgctcc atttgacaaa gcaaattgag agaacgcttg ctcactcatt
    43261 gttccttcag cagtaggcat agcaattcca tattgtttat tctctttatc tgtgaaatgt
    43321 tgagcaattt ttaaaatatc atcccaattt tctggttctg aaaaaccagc ttctgataat
    43381 ttttctttgt cataccaaat accttgaacc cagccgctaa ttggtgcagc aatatagctt
    43441 tttccatctt ctgaacgaac aaggtttttg gctccgtcat aataattatc ttctccagct
    43501 tcctcgataa cgttttggac tgccgtctga tcaatcagtt catctttatc catcacttta
    43561 gcaaaatcct gactgacttc cattacttct ggtaatttac cggaacgagc taacgtaacg
    43621 atttttgtat tgaacgctga ttcttctacc ggcacttgct tgattttgat gtctggattt
    43681 tctttttcaa aatcagcaac cagttcattg atcacactta atcgttcctg ttcgacagaa
    43741 gagtgcatga attgaatcgt tgtctgttgt gattcgttag agctttgact ttcaccacaa
    43801 gcagtaagaa gaaatccagt agctagcaga caggtagtaa caataatttt tttcattttt
    43861 ttccacctct tattttatta ttttcagcca catatattca tacggctgga atatcaactt
    43921 tcgttcttga ctgcaatgga taatttgtcc agaaaacagg tctaggtaat ctccttttgg
    43981 taaaagataa cctgctgatt gattggaaaa attatggata actaagactt tctcttcctt
    44041 cgcttcgcga ataaaactga taaaagaatc tgctgagtcc agtaagtaaa tcaaactatt
    44101 cggatggaag gctttttctt tttttcgaat agatagcatc tgggtcaatt caccatatac
    44161 tgctgttctt aatggatctg tctgcaactc tttctcaata tctgctaaca aaaatttttg
    44221 ccgattgatt tttcgattct ctcctgtttt ttctacgcct ttgtaatcat ttcgacttcc
    44281 cagcacactt tgaatataaa ttgccggcac gcctggtaac gttaccaaaa atgaatgagc
    44341 agctaaaaag cgtttgcttc tccattccgt cgtatctgtt ggagaactta acgcatctag
    44401 atacgtagcg tttatctcat atggactggt cgttccatct gggtttttct tgtagtttac
    44461 tcgggcaccc tctttcttca gctgttccac taattcaagg atcgtttttt ccggcagaat
    44521 acctcgtacc ggattcaatc cgataccgtc atgggaggct aaaaaattaa aaaaagttgt
    44581 ttttttcgat gcgaaatcga tggtttttaa ccattctttc aacttacttg tattacccga
    44641 acgaatcgct tgaagggtca aaggtggtag cgaaaactga tagaccatct gtgcttcatt
    44701 ctcgccattc ccaaaataac tgatattatc tttgtgtggc acatttgtct cagtgatcaa
    44761 taccgttcct ggagctgctt catcagcgat tgcacggaat aattggatga ttttatgcgt
    44821 ttctggcagg tgtatacaag aagttcctag ttctttccat aaaaatccca cagcgtccaa
    44881 gcgaataaat gaagcgcctt tttctaagta aaacaaaaga atatcgatca ttttcaataa
    44941 aacttctgga tttttaaaat tcaagtctac ttgatcttcg ctaaaagtcg tccatacgtg
    45001 tttttctttc ccgtttttgt caatgaacgt tgtaagtaac gggctggtcc ttggtctagt
    45061 cacgctgctt gtatctgtat ccagtggcaa atcaataaaa aaatctttgt acgtatcatt
    45121 caagtttaaa tattcctgaa accaagtact ttcggcagac atatgattgc agacaaagtc
    45181 gaacattaac cgtgtttcgc ttctcatttc ttctatatct tcccatgtgc ccaaacggtc
    45241 gttgattgcc tgataattta caacggagaa accatcatca gatgtatatg ggaaaaatgg
    45301 caagaaatgt acaactctaa atgtatctgc caaatacttt tgataaaatt tcttaaatgt
    45361 acgcaaagtt ggttgctgct cttcaaaaaa ttgatcccca taagtaatca agaaaatatc
    45421 ttcttcgtcc caatgcagtt tgcctgcctg gcctttcttc tgctgataaa cactgacttt
    45481 ttgttcaatc atagaggcgg ttttctcaga caaatctgag tcgcgataaa tcgcttgtaa
    45541 aagttttgta tacatcggat tcccctttct tttttgggag cgttcccaac gatttgatca
    45601 tattatggaa aacgcttact gtcaatagca tttttttaaa taattttgat atacacaaaa
    45661 atacaaataa gaaagcttat gtatcaataa ttaatagctt cttaaaaaaa tatggtctct
    45721 catgatcatg caagctattc ctaaattttc aaaatcatag acaaaaaaga atgtctattg
    45781 tactatggaa ttattctaaa acgctcccaa aaaggaggtg catataaaat tgaaacctac
    45841 tatttatgac attgcgaaaa aagctaatgt ctcaaaatca actgtctcca gagtattaaa
    45901 taaccagcca aatatctctg ataaagcaaa agcaagtgta cttcaagcaa tcaaagaatt
    45961 gaattatgaa ccgagcaaaa ttgcaagagg actgtcagga aatggttttg acgcgattct
    46021 agcattatct catcgtactt ctcatacgac ctatggcaat cctttttttt cagatgttat
    46081 tcaatccatt tctgccgttt ctgaacaaaa taacttcgac ttgattctac aaacggcaaa
    46141 aacaccagaa gaagagctag aaaaatgcgc gaaaaagatc caagaaaaaa tgatccgagg
    46201 aattattatt ttaagctcta cgatggatga aacacttctt tttgaattgg atcaatataa
    46261 tattcctatt gtggtaatcg gaaaagtcgg aaacgactac acgaacatct actcagtgga
    46321 cacggataat ttccaggata gttacgattt ggtggaaaca ctgatcaaga atggacaccg
    46381 tcatatcggc tgtctccatg ctccgacaga agtttatgta tccaatgatc gtctcaatgg
    46441 ttaccgtcaa tgcttatttg atcaccacct agatatccgt aatgaatgga ttatagacgg
    46501 cggctttcgc ttagaagata gcatggcagc aatgaatgat ttaatgaagc tacgagaaag
    46561 accaactgcg attttttcta ccgatgcatt aaaatcattg agtatttaca aagtggcaga
    46621 acaatctgga aagcagatac ctgatgatct ttcgatcgca ggattcagtg atcccttatt
    46681 gtcctcccta ttttcgccac agttgactcg gatagacatt ccgacaaatc agttaggaat
    46741 caaagccaca gaacttttat tccaactaat ccaccaccaa taccctgaag aaaaaagaat
    46801 cattctttca accgagatta ctctcacaga ttcgatccaa caacaagaaa tgtagaacag
    46861 aattataaaa gaacagaaac actgaggata agtcagttac tctgttcttt tttcaatcac
    46921 tcatccctcg ttaccccctc ccggtatttt agcgaatttt tcttattttc catctgtttt
    46981 agatagctgt ggataactat aatgtttgtg ttaaactatt ttttccacag ggaagaaaaa
    47041 actattttta accacgttgt gtataagttt ttatagttcg tttttttaaa cacatttacc
    47101 cttatttcaa tccatgttat ttggggatac ttatctctaa aacataaata gaataacaga
    47161 catgtctact ggttttgttt tattcgagga attattcaat aatagctagc aaaatattaa
    47221 aaataaccgc tctatcttcc catcaattta ttttgcattc aaaaaatgat ctatctttac
    47281 ttttgttgat tgacttctct tggaagatga tcgttccgat accttaattg gatacgaacc
    47341 gatgttgtta agatcctttc ccacttttct tctagttaga caaattattt tagacaaacc
    47401 aaaaaagagg ttgtgacaat aatttgtcac aacctctttt ttaaaatatc tattttgttt
    47461 gattgttcat tgcgtcttct gcagccattt gcgcttcaat atctgaaata ctgtagacat
    47521 tttcgcttgc tacaccgact tcttttggtt ccatgtcacg ataacgttgc ataccagtac
    47581 cagctgggat gatcttacct ataataacat tttctttcaa accaagaaga ggatctttct
    47641 taccgcggat cgcagcatcc gtcaagacac gagttgtttc ttggaatgat gcagcagata
    47701 agaaactatt tgtttctaat gatgcttttg tgatacctag taagacaggt cgagaagttg
    47761 caggaacgcc tcctgagact agcgtattgt agttttgatc tttaaagtct gcgatgtcta
    47821 ataatgtacc tggtaagata tctgtatcac ctggatccat tacacgaact ttacgcagca
    47881 tttgacgaac cattacttcg atatgcttgt cgccgatttc taccccttgc atacggtaaa
    47941 cacgttgtac ttcacgaagc aagtagtttt caacagataa tacatcgcga acttgcaaca
    48001 attgttttgg atcgattgat ccttctgtca atggtgcacc acggtggatc atatcgcctt
    48061 ctgctacttt catacgtgct gtataaggaa cagtatacgt acgtgtatct gtttttcctt
    48121 tgattgttac ttctttggta cgtgttgcag gatcttctga gatatcgatg acatcccctg
    48181 ttacttctgt gatcactgct tgccctttcg gattacgtgc ttcaaagatt tcttggacac
    48241 gaggaagacc ttgagtgata tcgtctccgg caaccccacc tgtatggaat gtacgcatcg
    48301 tcaactgagt accaggttca ccgattgatt gagcggcgat cgtaccaact gcttctccga
    48361 cttcaacgtc agagccagtt gcaaggttgc gtccgtaaca atgtttgcag acaccatgtt
    48421 ttgtattaca tgtgaagaca gaacggattg tcactgtttc gacacctgca tcaacgattt
    48481 gttttgcgat gtcttcggaa atcaattggt ttcctgcaat gatcaattca tttgtttcag
    48541 gatgacgtac ttctttacgg gtgtaacgtc ccactaaacg atcttctaat gattcgatga
    48601 tttcatttcc ctcgcggatg gcttggattt caagacctcg gtcagtaccg caatcttctt
    48661 cacggatgat tacatcttgg gccacgtcaa ccagacgacg agtcaagtaa cctgaatcgg
    48721 cagtcttcaa ggctgtatcg gtcatccctt tacgagcccc gtgagttgag ataaacattt
    48781 ccaagacgga tagtccttca cggaagttcg aaatgattgg caattccatg attcgaccat
    48841 taggagcggc catcaaacca cgcattccgg caagctgtgt aaagttggaa atgttaccac
    48901 gagctccaga atcagacatc atgaagattg gatttttcgc ttccaaacct tccatcagtt
    48961 tttgttggat gctgtctttt gcagcattcc aaacagcaat gacacgttca taacgttcgt
    49021 catctgtgat cagaccacga cggaattgtt ttgtaatagt ttcaacttgt ttatgggcat
    49081 tttcaatgat ttcttgtttt tcattcagta cactgatgtc agcgatccct actgtgatac
    49141 cggcatgtgt cgaatgtttg taccctaagt ctttcatacg gtcaagcatc ttagaagttt
    49201 ctgttacttt gaatcgtttg aagacttctg cgatgatgtt tcctaagttt ttcttcttga
    49261 acggtaatac taattcttgc tctttgatat gtgcaggaat atcagtacca gcttcaacaa
    49321 agtatttgtc cggtgtttgg acggtcaagt tgaagtctgt tggttcattc agataaggga
    49381 attcaggagg catgatctcg ttgaagatga tcttaccaac tgttgtgatc atcgtacgtt
    49441 ctttttgcca ttcagtaaat ggtttttcac ctaatgagtt agggttcaca ccgatacgtg
    49501 aatgtaaatg aacatatccg ttgcgccatg cgataacggc ttcgttttga tctctgaaga
    49561 ccattccttc gccttcgcgt ccttcttctt ccattgtcaa gtagtagtta cctagaacca
    49621 tatcttgaga aggagtaaca actggtttac catctttagg gttcaagatg ttttgagcag
    49681 ctaacatcaa catacgtgct tctgcttgtg cttcttcatt caatggaacg tggacagcca
    49741 tttggtctcc atcgaaatcg gcattataag cttcacatac aagtggatgc aaacggattg
    49801 cgcgtccttg tactaaaact ggttcgaatg cttggatacc aagtcggtga agcgtaggtg
    49861 cccggttcag caatactggg tgttccttga ttacgtcttc taaaacatcc catacttcgt
    49921 cttcttgacg ttcgatttta cgtttcgcat ttttgatgtt tgaagctagt tcgcgttgaa
    49981 caagctcacg catcacgaat ggtttgaata attcaatggc catttctttt ggaagtccac
    50041 attggtacat cttcaagaaa ggtccaacaa cgataacgga acgacctgag tagtcgacac
    50101 gtttacctag caagttttga cggaaacgac cttgtttccc tttcaacata tgagaaagag
    50161 atttcaatgg gcggttacct ggtccagtaa ctggacgtcc gcgacgaccg ttatcgatca
    50221 atgcatctac tgcttcttgc agcatacgtt tttcattttg aacgatgatt ccaggtgcat
    50281 tcaagtctaa caaacgtttc aaacggttat tacggttgat tacacgacgg taaagatcat
    50341 tcaagtcact tgttgcaaaa cgtccacctt ctaattgaac cattgggcgt aaatctggtg
    50401 gaataacagg gataacgtcc ataaccatcc agcttggttg atttcctgaa gcgcggaatg
    50461 cttctaaaat atccaaacgg cggattgcac gtgtacgttt ttgtccttgt gcagatttca
    50521 attcttcttt caattcggct gcttctgcat ctagatcaac attatcaagt aattgtttaa
    50581 tcgcttctgc acccatagca gcttggaatt cttgtccata ttgttcacgt ttttcgcgat
    50641 attcgcgttc tgtcaacaat tgttttttct ctaaattcgt atttcctggt tcgatgacta
    50701 catatgaagc aaaataaatg atttcttcca aagcgcgtgg gctcatgtct aatacaagac
    50761 ccatacgtga aggaatccct ttaaagtacc agatatgtga aacaggagct gctaattcaa
    50821 tatgtcccat gcgttcacgg cgaactttcg aacgagtaac ttccactccg catcgatcac
    50881 aaacgattcc tttataacgg atacgtttgt attttccgca ggcacattcc cagtcttttg
    50941 taggaccaaa aatccgctca cagaacaacc cttcacgttc aggttttaag gtacgatagt
    51001 taatcgtctc aggttttttt acttcaccgt aagaccagct tctgattttt tcgggagaag
    51061 ccaaacctat ttgcatactt tcgaatttat ttacatcgat caaaaggggt tccctccatt
    51121 tcatttaatg gcaaaccgca agacggctga tcttcgaccg ccttgcagct catagaccgg
    51181 attagtctaa attatcttct gcggtttcaa agttttggat gacatcgtct ttttcatctt
    51241 ccacttgttc agcagctttc ttttctaatt ctttggcagt ttgctgttcg gcaaattttg
    51301 tcaaagcatc aacagtgatc aaatcgtcgt cttcatcgtc catgtcgcga agttcgatct
    51361 ctgtttcttc gatatccaag acacgcatgt ccagacctag tgattgcaat tctttcacca
    51421 atacgcggaa tgattccggt acacctggtt ttggaattgg ttcacccttg acgattgctt
    51481 cgtatgtttt cacacgtccg actacgtcat ctgatttgta tgtcaagatt tcttgtaaag
    51541 tataagccgc accgtaagct tccagtgccc atacttccat ttcaccaaaa cgttgtccac
    51601 caaattgagc tttacctccc aatggttgtt gtgtaaccaa tgagtaaggt ccgattgaac
    51661 gtgcatgcaa tttgtcatcg accatgtgag caagtttgat catgtacatc acaccgacag
    51721 acacacgtcc atcaaatggt tcacctgtac gtccgtcgta cagaacagtt ttcgcatcgc
    51781 tggccatacc ggcttcacga actgtttccc atacgtcttc atcacttgca ccatcaaata
    51841 ctggcgttgc tacgtggata cctaactgac gtgcagccat acccaagtgt aattccaata
    51901 cttgcccgat gttcatacgt gaaggcaccc ctaaaggatt cagcatgata tcgattggtg
    51961 ttccatcagg taggaatggc atatcttctt ccggcataat acgggataca acccctttat
    52021 ttccgtgacg accggccatt ttatcccctt catggatttt acgtttttga acgatataaa
    52081 cacgaactaa catgtttacg cctggtgaca attcatctcc agcttcacga gtaaagattt
    52141 tcacatcgtg aacgataccg ccgccgccat gtggtacacg taatgatgta tcgcggactt
    52201 cacgagcttt ttcgccaaag atcgcatgca atagacgttc ttctgcagat aattctgtta
    52261 ccccttttgg cgtgactttc cctacaagca aatcgccatc ttggacttct gcaccaatac
    52321 ggatgatacc catttcgtct aaatctttta atgcgtcttc cccgacatta gggatttcgc
    52381 gtgtgatttc ttcaggtcct aattttgtat cgcgggcttc tgattcatat tcttcaatat
    52441 ggatagaagt gtatacgtca tcttttacca aacgacggct catgatgatc gcatcttcat
    52501 agttgtaccc ttcccaagtc atgaaaccaa ctaaaacgtt ttggcctaga gccatttcgc
    52561 cttgttccat agatggtccg tctgccagag tatccccttt ttcgactttc tcacccaaat
    52621 gaacgattgg acgttggttg tagcttgttc cggagtttga acgacggaat tttgttacat
    52681 cgtatttatc taatgcaccg ttgtcgcggc gtacgcggat ttcagaagca tcaacgtatt
    52741 caacgacacc gtcatgttta cataacaaag cagctcctga gtcatgcgct gatttgtatt
    52801 ccataccagt accaacccat ggtgcttgag gattgatcaa cggcactgct tgacgctgca
    52861 tgttggcacc catcaaggca cggttggagt catcgttttc caagaaagga atacatgctg
    52921 tcgcaacggc aactacttgt ttaggtgata cgtccatgta gtctacttta tcaatagata
    52981 cttctaagtt ttcactttga gcacgagcca taacaacgtc ttgagcaaat gttccatctt
    53041 cattcaatgg gctgtttgct tgggctacga tgtaatggtc ttcgatatca gctgtcaagt
    53101 agtcgatttg gtcagtaaca cgacctgttt cacggtctac acgacgataa ggtgtttcga
    53161 taaatccgaa tttatttact ttcgcataac tggacaaact attgatcaac ccgatgtttg
    53221 ggccttcagg agtttcgatc ggacacatac ggccatagtg ggagtagtga acgtcacgaa
    53281 cttcataacc ggcgcggtca cgagtcaatc cgccaggtcc taaggctgaa agacgacgtt
    53341 tgtgtgtcaa ttcgccaaga gggtttgttt gatccatgaa ctgtgacaac tgagaagaac
    53401 caaagaattc tttgatactt gccacaactg gacggatatt gatcaattgt tgaggtgtca
    53461 atgtttcagt atcttggatc gacattcttt cacgaaccac acgttccata cgtgctagcc
    53521 cgatacggaa ttggttttgt aaaagttcac cgactgaacg gatacgacga tttcctaagt
    53581 ggtcgatatc atcgacattg ccgatacctt ccatcaagtt caagaaatag ctcattgaag
    53641 caatgatgtc ggctggacga accgttttta cagctgcttc tggatagccg tttccgatca
    53701 cgtttacttc acgttcaggg tctcttggtg aaaatacttt gatgacttgg acagtcattg
    53761 gatctgtgac cacaccgtct tctgatggat agtaagtcac tgaatttagg ccattatcaa
    53821 tgaaaggagc tagtgtttcc atgacttggt gagtcagaac tgttcctttt tcaacgatga
    53881 tctcgcctgt ttctggatca actaatgttt cagctaatgt cagattcaat agacgtgttt
    53941 tcaaatctaa ttttttgttt actttgtaac gaccaacgtt tgctaagtcg taacgttttg
    54001 gatcgaagaa acgagcattc agcaagttac gtgagctgtc tgctgttttt ggttcgcctg
    54061 gacgcaaacg ttcgtaaacg tctttcaaac cttcttctgt tcttgagtcg cttgcgtttt
    54121 tatgcaagtc tttttcgact gtattgcgta atgtttcgct gtcgccgaag atttcaaaga
    54181 tcgtatcatc ggaaccaaat cctaacgcac gaactaatac ggttaaagga atcttacgtg
    54241 tacggtcgat acgtacataa gagatgtctt ttgcatcagt ttccatttct agccaagctc
    54301 cacggttagg gataacagta gaaccgaatc cttcttttcc gtttttgtcg acttttccat
    54361 ggaaatagac acctggtgaa cggactaact gagaaacgat tactcgctct gccccgttga
    54421 tgatgaatgt tccttgttct gtcattaatg ggaaatcacc gaagaatact tcttgtgctt
    54481 tgatttcgcc agtctcgcgg tttgtcaaac gcaatgttac atgtaatggt gcagagtagt
    54541 ttgcatcatg cgcacgagct tctgctactg tatactttgg ttctttcaat tcataatcta
    54601 caaattccaa agatagattg ccattgaagt catcgattgg caaaatgtct tcaaacattt
    54661 ctctaagtcc ctcatctaag aaccattggt aagagtctgt ttgaatttcg atcaaatttg
    54721 gtaattccaa cacttcactg attcttgcga aacttctacg ttcgcgatgt tttccgtatt
    54781 ttactacgtg tccagccaag ctcttcaccc ctctaaaatg tcattcaaaa agactacccg
    54841 atcaattgtt acaataatat ttcaaatatt atttttaggt aacaacagac attttttgcg
    54901 gcttttaggc aaaaaaaaac caaaaataga acattctctt gaaaccttac ttcgtgagct
    54961 tctacttttg tttccttata ttaaagccga aacggacaat atttcgtttc tgccttttct
    55021 tcatcagata gtttttgcaa cttcatatac tacacttatt ttctataaaa gtcaacactt
    55081 cctggcgttt cttctgcttt ttcgcaacat tttcttaatg ttttcaattt tatgttttca
    55141 attatctgac aattcttaat tgacagacct ttttatctcg gttatacttt agaaaattca
    55201 ttttgtggag gaacttctat gcgaaccaac atcaaccaaa tcgcaccaac acaactgaat
    55261 aacttttact ttagctactt tagataggtt tgtattcatc atgatggata caaacgttaa
    55321 acgacagttt gtatctatga tggctaaaga actttgtatt gcagcaaaaa gccacgtaga
    55381 caaaatgcta agtggctgag cagtgaaaat acaaagtaaa agtatcaagc attctacttt
    55441 ttcaatttat tttccgactt ttcaatccat ttggacattt tgtctgaatg gattttttgt
    55501 ttcccaaaat taaggaggaa aaagaaatga aaaaaaatat aatcatcgga ttaggcgctg
    55561 ccctgctact agctttagga ggttgcgcac aaaaagacaa ttccgcagag gcatcagatg
    55621 gacaaaaaac aattggcgta ttgcaacttg tacaacataa ctcgttagat gctgcctata
    55681 aaggattcaa agaaggatta gcagaagaag ggtataaaga aggcgataat ctaacaatcg
    55741 attatcaaaa tgcccaaaac aatcaagaca acctgaaaag tatgagtgag aaactcgtca
    55801 aagaagatcc tgatttgcta cttggaatcg ccactccagc agcacaatct ttattaaatg
    55861 aaacaaccac tatcccgatg actgtcacag cggtcacaga cttggaacaa gcccatttag
    55921 tcacatccaa tgaaaaacct ggcggcaatg tgactggcac gacagatatg gtgccaatcg
    55981 aaaaacaaat cggcttactg ttaaatatcg tgccagacgc caaaacaatc ggcatcatgt
    56041 ataacaacgg tgaagcaaac tctaagatcc aagctgattt ggcagaaaaa gaattgaaaa
    56101 aagcgggcgt caaagtcaaa gtactgacag caaattccac aaatgatgtc caacaagtga
    56161 cgaaaagtct agctaaagat gtagatggaa tctatattcc tactgataac acgttcgcaa
    56221 gtgcggcaag tgttgtcggt gaagtcgcaa aagaaacaaa aacacctgtc gttgctggcg
    56281 cagttgatca agtcaaagac ggcggtctag caacagtagg aatcgactac gaaagcttgg
    56341 gcaaacaaac agggatcatg gcagcaaaaa tcttagacgg caagaatcca agtgaacttc
    56401 ctgtcgaaac agcgaatgat ttggaactgt atgtcaataa agacatggcc aaagcattag
    56461 gcatcaatcc agacagcatc aaagaagctg aataaaacac aggaggattc tcatgacaaa
    56521 tttgctctct cttttcttat catctgcatc gcaaggggtc ttatgggccc tacttgcgat
    56581 tggtgtatac gtcactttcc gtatcttgga cattgccgac ttgactgctg aaggaagctt
    56641 tcctttaggt gcagggatcg cggcagtaag tattacaaat ggctatcatc cattgacagc
    56701 ttgtcttcta ggctttttag ggggtgcggc agcagggctt gtttccggac tgcttcacac
    56761 aaaattgaaa attcccgccc ttcttgcagg gatcatcacc atgactggtt tatattctgt
    56821 cacatcccgt gtgatgggtg cgccgaacat ctctttattg ggtcagccaa cgatctttca
    56881 ttgggtcgag tcattcggca taacaaaaga caacgctgta ctgatcgtcg gtctgctttt
    56941 tgctttgatc gttgtatgtt tacttgtttt gttcttacgt acagaaacag gacttgctat
    57001 tcgtgcaact ggcgataatc tggcaatgag cgaagcaaac gggatcaaca cagataatat
    57061 gaagatcatc ggttatatga tttctaatgg atgcattgct ctttctggct ccttacttgc
    57121 gcaaaacaac ggctttgctg atttaaattc tggtattgga acgatcgtaa ttggacttgc
    57181 ttctattatc atcgcagaag ttttgttacg taaccagcca ctatttctcc gtctcttgac
    57241 tgtcgtttta ggtgcggtca tttatcgttt tattttagcg ttagtcttcg aactgaatgt
    57301 tgaaccaagt gattcgaaac ttgcttctgc tttcgtgcta gtgatctgtc tttctttccc
    57361 gcagatccag caaaaattcc atttacctca aaaaaagaaa ggcggtagtg tcaaatgaat
    57421 gacgtcttaa cattggaaaa tctccatcat acctttgaaa aaggaacgat caacgaaaat
    57481 catgtcctga aaggcattaa tctttcctta gatcccggcg acttcgtgac gatcatcggt
    57541 ggaaatgggg ctggtaaatc tactttgctg aacagcatcg ccggtacatt ttctgtcgat
    57601 cagggtcaaa ttttattgaa tggaaaaaat atcacgaaaa aatctgttgt cgaacgttcg
    57661 aaatccatca gtcgcgtatt ccaagatcct aaactaggga cagccgttcg tttaacggta
    57721 gaagaaaatc ttgctcttgc tatgaaacga ggaaaaaaac gcggcttctt ccgtggtgtc
    57781 aaaccacaag accgaacatt tttcaaagac cagctggttc ggctaaattt ggggttggaa
    57841 aatcgtttat cctcagaaat cggtttgctg tctggaggac aacgtcaagc tattacgtta
    57901 ttgatggcca cattacagcg tccagaactg atcttattag atgaacacac tgcagcgctt
    57961 gaccctgcta cttccaaaac ggtgatggaa ttgacagaaa agctgatcac tgagcagaat
    58021 ctcactgctt ttatggtcac tcatgacatg gaagacgcga tccgctatgg gagtcgactg
    58081 atcatgctgc atcaaggaag gatcgtcgta gatatccagc aagaggaaaa acagcagctc
    58141 acagtgcccc aattattagc gttgttcaaa caaaacagcg gcacggcatt aaaagacgat
    58201 caagtacttt tatcttcata atcagaaaga ggatgggaca aaaaatgaac gcccaccctc
    58261 ttcttttttc tctttccttc tttcgttttt gctttatgta tcaaccgttg tttcttcgaa
    58321 aactattttg ttctctcctt cttcctgata gaatggatgg gaaaggagct tgatgccatg
    58381 acaacgaaag acaaggtact tcaattattg aaaaagacac cagattttct ttccggagaa
    58441 aagttggcac agcaactgga agtttcccgg acaagtattt ggaaagccat caaagaattg
    58501 gaaaaggcag gctatcgttt tgagcacggg cctacagggt atcgttacct gccctctgac
    58561 gtactagatg caaaagaaat ccagcaagag ctacggtcgt ttattcctga tttgaaagta
    58621 caaacgatgt tgacttctga atctacgatg aaagatgcca aactggcagc agctcaagga
    58681 gattctgttt cgaagttatt tgttgctgat acacaagaac aagctcgtgg acgttttgga
    58741 cggccttttt tcgctgaacc tggacgagga atctacatga gtctcttgct ccatccagac
    58801 aaacggtttg atgaattgcc tcaatatacg atcatcgcag ccagtgcctg tgtgaaagcc
    58861 attgaatctg taaccggtcg ttctgcttcg atcaaatggg tcaatgatat ctacatggat
    58921 ggaaaaaaag tctgtgggat tttatctgaa gcagtcagtg atatggaaag cggcaggatc
    58981 agtcatatca tcattgggat cgggcttaat ttttctgttc ctcaaaatca ttttccagct
    59041 gatctccaag aaaaagccat ctctgtcttt cccgacggac aagctagtgt cacaaggaat
    59101 cagctaatca gcaaaatctg gcaagaattg ttcacttatc tttctcaccc agaaaaagcg
    59161 ttggacttct ataaagaaaa atcattcgta ttgggaaaaa ccgtgtcgtt caatcaaaaa
    59221 ggaacgactt atgtcggtct tgcaaaagaa atcggtgatc atggcgaact gatcgtccaa
    59281 acaaatgaac agaagatgag tttgtcttct ggcgaaatca gtctcacatc tatccgtacg
    59341 caataattat cagatttcac aaaaggacac ctgatctcat acagtgtcct tttttctgaa
    59401 ttctcttcaa aagactctcc ttattctatc agctgacagt ttctctatcc tctagaaaaa
    59461 ggtattctaa aaatatctat aaagcatggt acactttctt taaatgaatc aatgcaaaaa
    59521 acaagagagt catcagttta cacgatcaaa agagatagca ggccgcttcc tttttcaatc
    59581 ttatagatag accatgggta acgataaaaa caaaaaagaa cttgcgactt attttgccgt
    59641 aagttctttt ttagctagtg ccttaatctc ttaatcccaa caaacgtctc gcatagatca
    59701 cctgaccaga gtgcatagca gcatcatcaa taatagaaac gagacgcatt cctcgtgtga
    59761 ctggtggtgt ccagttctcg tcaattactt catctagctc ggaaggttcc agccttctta
    59821 agtaagaaat agcaaaatca gcagctcctc gcaagtatcc tagcagatct tctatttgat
    59881 tagcttggat ctgctttgct tgttccagac tatgcttcca atcttgttcg ttatctgcta
    59941 tcgtcatcgg aaaccggctt tcccagtctt gactatgcca aattggagaa gttcctgcta
    60001 aatcagcaat ctggaaatct aattctcgag cggtatgcca agccagccaa gtcattgatt
    60061 tgatctgcgg ggctctatct tccactggaa aacgattggc ctcctcaata gagacgcctt
    60121 caaacaaacg ttcaaaccga tcgtatgccc gatccacact ctcgcatagc atatctaaat
    60181 aatccattta ttttcctcct ttttatttat cctacttact ttttcctaat tctaggatac
    60241 ctacttatat gttactacac acccttattt tttacacttt aacagtcacc atcatcaata
    60301 gtttggagat tgaaagaaaa agatagtgtc gaactatcaa ttgaacaaga agcaacaata
    60361 tgaacgtttc attaatattc tttaaataaa caatgatttt tcaaacgaac agtttaagac
    60421 taggagaaaa agagtataat aggaaaatgt ttgaaaggaa aggaagggga aaaatgaaaa
    60481 aaagggcaag tttactagtc ctagttgctt tgttgttcaa tatcttttcg tatggtgtgg
    60541 ccgtttcagc ggaaacatac attcctaaag accctgggaa tatttataat gatctaactg
    60601 gtaactatgg cttgttagga attgctagtc aattccacgt atttgctaaa aataagacaa
    60661 ctgtgaatgc acatacagac ggaaatatag caacacatga acttgatgca aaaaataatt
    60721 ttggtacaga gcttcatgaa ggtttattga accaagaaat aaattatata caaaaaactg
    60781 attctttcgc taattcttca ggcataccta caggtagcac aagaatgaat aaatttgtcg
    60841 ttggcagtaa cgtggatgta gcacttcaag atggtcatcc tacagtcaat ggatccaggc
    60901 ttgatcactt aactccagat gatttttata aagatcgtgc tgggcatgaa tatattgatt
    60961 tcgagcagga atttgctaaa ttgaatgtag cagcaaatga tcttgcaacg atcactccag
    61021 ctaaaacata tactgctgca gattttccag acatgaacaa tcggacaatc gatttaactg
    61081 atttatcaga taccgggttt ttattggtaa atatcgatgc agaagtgtta acgatgaata
    61141 cgccacttca aatcattaat ccaaatgatc aagtagttgt atttaatgtc atcaacagtt
    61201 cttctgcatt gaacgtacag tcaccaatca aatacaatga tcgttcaaat catgaaacag
    61261 aagatttttc ggatgcgaat atctcttgga attttggaaa tgagatgact gatttgacaa
    61321 tcagtgctcc ttttcaagga acaatccttg cgcctaatgc tactatccgc attactcaaa
    61381 accaagacgg aacgattata ggaacaaatg tgattttaga tgcagctacc aatcgttggg
    61441 atcctaacga aatatttatc agcgacaatg gtacagatac gacagacaca agcgacagta
    61501 cagatacatc taccacaagt gatagctcag attcatcaac ttcaagcgac agtacagata
    61561 ctacctctac cacaagtgat agcacggata catcagcttc aagcgacagt acagatacta
    61621 cctct
//
LOCUS       DARBDN010000006        60875 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000006 DARBDN010000000
VERSION     DARBDN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.006"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            199..2733
                     /gene="secA"
                     /locus_tag="SCH06_000404"
     CDS             199..2733
                     /gene="secA"
                     /locus_tag="SCH06_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEG1077008.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            2859..3960
                     /gene="prfB"
                     /locus_tag="SCH06_000405"
     CDS             join(2859..2930,2932..3960)
                     /gene="prfB"
                     /locus_tag="SCH06_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEG1077009.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4065..4751
                     /gene="ftsE"
                     /locus_tag="SCH06_000406"
     CDS             4065..4751
                     /gene="ftsE"
                     /locus_tag="SCH06_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEG1077010.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4735..5628
                     /locus_tag="SCH06_000407"
     CDS             4735..5628
                     /locus_tag="SCH06_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077011.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            5780..7228
                     /gene="cls"
                     /locus_tag="SCH06_000408"
     CDS             5780..7228
                     /gene="cls"
                     /locus_tag="SCH06_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEG1077012.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            7565..8422
                     /locus_tag="SCH06_000409"
     CDS             7565..8422
                     /locus_tag="SCH06_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEG1077013.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8537..9457
                     /gene="pstC"
                     /locus_tag="SCH06_000410"
     CDS             8537..9457
                     /gene="pstC"
                     /locus_tag="SCH06_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEG1077014.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9457..10341
                     /gene="pstA"
                     /locus_tag="SCH06_000411"
     CDS             9457..10341
                     /gene="pstA"
                     /locus_tag="SCH06_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEG1077015.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10356..11162
                     /gene="pstB"
                     /locus_tag="SCH06_000412"
     CDS             10356..11162
                     /gene="pstB"
                     /locus_tag="SCH06_000412"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEG1077016.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11178..11936
                     /locus_tag="SCH06_000413"
     CDS             11178..11936
                     /locus_tag="SCH06_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEG1077017.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11949..12626
                     /gene="phoU"
                     /locus_tag="SCH06_000414"
     CDS             11949..12626
                     /gene="phoU"
                     /locus_tag="SCH06_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEG1077018.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            12864..13895
                     /locus_tag="SCH06_000415"
     CDS             12864..13895
                     /locus_tag="SCH06_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEG1077019.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            13892..14659
                     /locus_tag="SCH06_000416"
     CDS             13892..14659
                     /locus_tag="SCH06_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEG1077020.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            14759..16327
                     /gene="liaX"
                     /locus_tag="SCH06_000417"
     CDS             14759..16327
                     /gene="liaX"
                     /locus_tag="SCH06_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HEG1077021.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16624..16944
                     /locus_tag="SCH06_000418"
     CDS             16624..16944
                     /locus_tag="SCH06_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEG1077022.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            16944..17294
                     /locus_tag="SCH06_000419"
     CDS             16944..17294
                     /locus_tag="SCH06_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEG1077023.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            17461..18399
                     /locus_tag="SCH06_000420"
     CDS             17461..18399
                     /locus_tag="SCH06_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEG1077024.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18414..19244
                     /locus_tag="SCH06_000421"
     CDS             18414..19244
                     /locus_tag="SCH06_000421"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEG1077025.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            19288..20313
                     /locus_tag="SCH06_000422"
     CDS             19288..20313
                     /locus_tag="SCH06_000422"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEG1077026.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20328..21266
                     /gene="galU"
                     /locus_tag="SCH06_000423"
     CDS             20328..21266
                     /gene="galU"
                     /locus_tag="SCH06_000423"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEG1077027.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            21391..21831
                     /locus_tag="SCH06_000424"
     CDS             21391..21831
                     /locus_tag="SCH06_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEG1077028.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            21834..22436
                     /locus_tag="SCH06_000425"
     CDS             21834..22436
                     /locus_tag="SCH06_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEG1077029.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(22495..23601)
                     /locus_tag="SCH06_000426"
     CDS             complement(22495..23601)
                     /locus_tag="SCH06_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEG1077030.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            23811..24812
                     /gene="ccpA"
                     /locus_tag="SCH06_000427"
     CDS             23811..24812
                     /gene="ccpA"
                     /locus_tag="SCH06_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEG1077031.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(25149..27494)
                     /locus_tag="SCH06_000428"
     CDS             complement(25149..27494)
                     /locus_tag="SCH06_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEG1077032.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            27773..28675
                     /locus_tag="SCH06_000429"
     CDS             27773..28675
                     /locus_tag="SCH06_000429"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HEG1077033.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            28888..30663
                     /locus_tag="SCH06_000430"
     CDS             28888..30663
                     /locus_tag="SCH06_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HEG1077034.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(30729..32315)
                     /locus_tag="SCH06_000431"
     CDS             complement(30729..32315)
                     /locus_tag="SCH06_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HEG1077035.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            32566..32790
                     /locus_tag="SCH06_000432"
     CDS             32566..32790
                     /locus_tag="SCH06_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEG1077036.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            32932..34683
                     /locus_tag="SCH06_000433"
     CDS             32932..34683
                     /locus_tag="SCH06_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1077037.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            34683..36467
                     /locus_tag="SCH06_000434"
     CDS             34683..36467
                     /locus_tag="SCH06_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077038.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            36793..37644
                     /locus_tag="SCH06_000435"
     CDS             36793..37644
                     /locus_tag="SCH06_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1077039.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            37698..39449
                     /locus_tag="SCH06_000436"
     CDS             37698..39449
                     /locus_tag="SCH06_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1077040.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            39453..39623
                     /locus_tag="SCH06_000437"
     CDS             39453..39623
                     /locus_tag="SCH06_000437"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1077041.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(39663..40565)
                     /locus_tag="SCH06_000438"
     CDS             complement(39663..40565)
                     /locus_tag="SCH06_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1077042.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            40796..42199
                     /locus_tag="SCH06_000439"
     CDS             40796..42199
                     /locus_tag="SCH06_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEG1077043.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            42199..43632
                     /locus_tag="SCH06_000440"
     CDS             42199..43632
                     /locus_tag="SCH06_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEG1077044.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            43777..44703
                     /gene="trxB"
                     /locus_tag="SCH06_000441"
     CDS             43777..44703
                     /gene="trxB"
                     /locus_tag="SCH06_000441"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEG1077045.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            44917..46644
                     /locus_tag="SCH06_000442"
     CDS             44917..46644
                     /locus_tag="SCH06_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEG1077046.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            46659..47009
                     /locus_tag="SCH06_000443"
     CDS             46659..47009
                     /locus_tag="SCH06_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEG1077047.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(47101..47961)
                     /locus_tag="SCH06_000444"
     CDS             complement(47101..47961)
                     /locus_tag="SCH06_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HEG1077048.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            48053..48481
                     /locus_tag="SCH06_000445"
     CDS             48053..48481
                     /locus_tag="SCH06_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEG1077049.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            48643..48819
                     /locus_tag="SCH06_000446"
     CDS             48643..48819
                     /locus_tag="SCH06_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEG1077050.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            48846..49292
                     /locus_tag="SCH06_000447"
     CDS             48846..49292
                     /locus_tag="SCH06_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HEG1077051.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(49446..50825)
                     /gene="brnQ"
                     /locus_tag="SCH06_000448"
     CDS             complement(49446..50825)
                     /gene="brnQ"
                     /locus_tag="SCH06_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEG1077052.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            51531..52502
                     /locus_tag="SCH06_000449"
     CDS             51531..52502
                     /locus_tag="SCH06_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEG1077053.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            52526..54718
                     /locus_tag="SCH06_000450"
     CDS             52526..54718
                     /locus_tag="SCH06_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HEG1077054.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            54735..55211
                     /gene="ybeY"
                     /locus_tag="SCH06_000451"
     CDS             54735..55211
                     /gene="ybeY"
                     /locus_tag="SCH06_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEG1077055.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            55195..55590
                     /locus_tag="SCH06_000452"
     CDS             55195..55590
                     /locus_tag="SCH06_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HEG1077056.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            55605..56504
                     /gene="era"
                     /locus_tag="SCH06_000453"
     CDS             55605..56504
                     /gene="era"
                     /locus_tag="SCH06_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEG1077057.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            56647..57459
                     /gene="recO"
                     /locus_tag="SCH06_000454"
     CDS             56647..57459
                     /gene="recO"
                     /locus_tag="SCH06_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEG1077058.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            57843..58760
                     /gene="glyQ"
                     /locus_tag="SCH06_000455"
     CDS             57843..58760
                     /gene="glyQ"
                     /locus_tag="SCH06_000455"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEG1077059.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            58762..60837
                     /locus_tag="SCH06_000456"
     CDS             58762..60837
                     /locus_tag="SCH06_000456"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEG1077060.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        19863 a        10760 c        13027 g        17225 t
ORIGIN      
        1 aaaacttgca gcagctactg acagctgccg caagtttttt tgagtttcct cctcttttag
       61 atgaaatatg aataaattat gaagttctta ctttaatacg cttaagatat ttcaattatc
      121 tataactaat gataaaatga aaagtaaagt ctacatagtc tggataatac acagaaggaa
      181 aaggagatta cacaacgcat ggccaatttg attcgttcac ttatcgaaaa cgataagaaa
      241 gaactaaaac gtttagatag cattgcaaaa aaagttgaag catacgctga ccaaatggca
      301 gcattaactg atgaacaatt acaggcaaaa actgctgaat tcaagggcag ataccaaaaa
      361 ggagaaacat tagatcaatt acttccggaa gcttttgcag tcgtccgaga agcagcaaaa
      421 cgtgtattgg ggttatatcc acaccacgta caattgatgg gtggaatcgt gcttcacgat
      481 ggaaatatcc ctgaaatgcg tactggtgaa ggtaaaacct tgaccgcaac gatgccagta
      541 tatctaaatg ctctgactgg cgaaggggta cacgtagtta ccgtcaatga atatttagca
      601 acccgtgact cgacggaaat gggcgaactt tataatttct taggattaac agtggggttg
      661 aatatcaact caaaatcttc ggatgaaaaa cgcgaggctt ataattgtga tatcacttat
      721 agtacgaata atgaattagg atttgactac ttgagagaca atatggtcgt ttaccgccat
      781 caaatggtac aacgtccgct gaattatgcc attgtcgatg aagttgactc aatcttgatt
      841 gatgaagcga gaacgccgct gatcatttca gggcaagcag aaaaatccac agctttatat
      901 acaagagcag acaacttcgt gaaacgtttg aaagaagaag aagattataa aatcgatgta
      961 caatcaaaaa caatcagttt aaccgaagca gggatcgaaa aagcagaaga aacattcggt
     1021 ttggataact tatacgacat tgaaaatact gcattgaccc atcacttgga tcaagcattg
     1081 agagccaact atatcatgct tttagatatc gattatgttg tccaagacgg aaaagtactg
     1141 attgttgacc agttcactgg tcggatcatg gatggacgcc gttattcaga tggacttcac
     1201 caagcaatcg aagctaaaga aggcgtagag atcgaagacg aaacgaaaac catggcgacg
     1261 atcactttcc agaactattt ccgtatgtac aagaaacttg cgggaatgac tggtacagct
     1321 aaaacagaag aagaagaatt cagagaaatt tataacatcc aagtatacca gattccgaca
     1381 aatcgtccgg ttatccgtga tgatcgtcca gatttgcttt acccaacatt acaaagcaag
     1441 ttccacgctg tcgtgcaaga tatcaaagat cgctaccgca aaggtcaacc tgtgttagtc
     1501 ggaactgttg cggttgaaac atctgagtta ttatcagata tgctgaatca agaacgtatt
     1561 cctcatgaag tgctgaatgc gaaaaatcac tttaaagaag cagagatcat catgaatgct
     1621 ggtcaaaaag gtgctgtgac gattgctacc aacatggctg gtcggggaac agatatcaag
     1681 ttaggacttg gggtaagaga acttggtggt ctagcagtta tcgggacaga acgacatgaa
     1741 tctcgtcgta tcgataacca gcttcgagga cgtgcaggac gtcaaggaga ccctggtatg
     1801 tcacagttct acttgtcatt ggaagatgat ttgatgaaac gattcggttc agaacgaatc
     1861 aaatctttct tagatcggat gaagatcggt gaggaagatg ctgttatcca aagcaagatg
     1921 ctgacgaaac aagtagaatc tgcacaaaaa cgtgtagaag gaaataacta tgacacacgt
     1981 aaaaacgtct tacaatacga tgatgtgatg cgtgaacaac gtgaagtaat ctataaacag
     2041 cgacaagaag taatcatgga agaaaaaagc ttatccaagc cactaatgaa catggtcaaa
     2101 cggacaatca gtcgtgtagt agatgcgcat acacaattag agaaagaaaa ttggaatttg
     2161 gaaagtatca tcgattttgc cggcagtact cttgtccatg aagatagtat tactcttgca
     2221 gatatcgaag gaaaaacagc tcaggagatc aaagagtatc taaacgaacg agcacaagaa
     2281 gtatttaata ccaaagcggc tcaactaaat ggtccagagc aactgttgga atttgaaaaa
     2341 gtcgtgatct tgcgtgttgt ggactctaaa tggacagacc atattgatgc aatggatcaa
     2401 ttacgtcagt caatcggctt acgtgcttat ggacagaaca atccattagt cgaatatcaa
     2461 acagaaggct ataagatgtt tgaagatatg gtaggcgcca tcgagtatga agtcactcga
     2521 atctttatga aagctgagat ccgtcaaaac gtacagcgtg aacaggtttc tcaaggaaca
     2581 gcttctcact cagaagacgg agatgccaaa gaaaatagta atactagcgc gaaaaaacag
     2641 ccaatccatg tgaacaaggt cggaagaaat gatccttgtc cttgtggaag cgggaaaaaa
     2701 tataagaact gtcatggaaa aaatgcaaac taatttctga cagcaggatt ggtgagacaa
     2761 attctttttt taagaattcg tctcaccttc tttctgttat ttgctgattc tgttagacta
     2821 gatataatga aaaaagtata gtgaaagaag gaaaaaacat ggaaatatcc gaaattcgaa
     2881 atctcctgac agaaatgcag gaaaaggtca caagcttcag gaggtctctt tgacttagac
     2941 cagctggaag aagacattgc ggaagcagaa gcaaaaatgg ctgaacctgg tttttgggat
     3001 gatagcgaag ctgctcaaaa agtgatcagt gaaaacaatg caaataaaga aacttatgat
     3061 caattccatt ctcttgctga agaactggaa gaaatcgaat tgatggtgga gatgttgcag
     3121 gaagaacctg atgcagccat gcaagaagaa gcagaaacac gtatcaatgc gctagatgaa
     3181 aaaatgaaga catatgaatt atctatgttg ttagatggtc cttatgatcg aaacaacgcc
     3241 atcgttgaat tgcatccagg ggctggcgga acggagtccc aagattgggg cagtatgctt
     3301 ttacgtatgt atacacgctg ggcagagcag catgggtatc aagtagagac actagattat
     3361 caagcaggtg atgaagcagg aatcaagagt gtgaccctac tgatcaaagg acacaacgca
     3421 tttggttatc tgaaatcaga aaaaggtgtt catcgccttg tacgtatctc gccttttgac
     3481 tcagcgaaac gacgtcatac ttctttttgt tcggtagatg tgatgccaga gcttgatgaa
     3541 acgatcgata tagaaatcaa tccagatgat ttgaaaatcg atacgtaccg agcaagtggt
     3601 gcaggtggtc agcacatcaa taaaacagaa tctgctgtac ggatcactca cttgcctaca
     3661 ggaacagtag tagctagtca ggcacaacgt tcacaattga aaaaccgtga gcaagcgatg
     3721 gggatgttaa aagctaagct ttatcaatta gaagtggaaa agaaagaaca agaagcagct
     3781 gcacttcgag gagaacaaaa agaaatcggc tggggttcac agatccgttc ttatgttttc
     3841 catccatatt ctatggtaaa agaccatcgg acaaacgtag agacaggaaa tgtccaagca
     3901 gttatggacg gtgaccttga tttatttatt gacggctatt taaaaatgca tctacaataa
     3961 gaacccattg ttaaattgaa ataaaattgt aagattttgc aagcatgttg aaacattgcc
     4021 atgctataat agctaaagac tgaaaaagat atggagagaa cgccatgatt gaaatgaagg
     4081 atgtaatgaa gaagtactca aatggtacga ccgctatccg caatctctca attgtcatcg
     4141 aacaaggaga gtttgtctat gtggttggtc cgtctggagc cggtaaatct acattcatca
     4201 aattgatgta tcgagaagaa aaagcttcaa aaggaacttt gaacgtcgca ggtcatgatc
     4261 taatagcaat caaaaaccgc gaagttcctt atctacgcag agaaatcggc gtggtgttcc
     4321 aagactataa attattacca agaaaaacag tatatgaaaa tgttgcgtac gctatgcaag
     4381 ttatcggcag aaaacctcgg gatatcaaaa aacgagtaat ggaagtgctg gaccttgttg
     4441 gtttgaaaca caaagttcga gtctttccta gcgaattatc cggtggggaa cagcaacgtg
     4501 tctctattgc tcgggcaata gtgaatacgc ctaaagtact tatcgcggat gaaccgacag
     4561 gaaatctgga tccagaaaac tcatgggaaa tcatgaaatt attagatcgg atcaatgccc
     4621 aaggaactac tgtcgtgatg gctacacata acagtacgat cgtaaatacg attcggcacc
     4681 gagtaattgc tatcgaaaac ggccgcatta ttcgagatca agcggaaggg gaatatggat
     4741 acgatgatta gaaccttttt ccgccattta ttagaaagta tcaagagttt gaaacgtaac
     4801 ggctggatga cagttgcttc agtcagtgcg gtaacgatca cattgacttt agtcggtgta
     4861 ttcatggcag ttatcatgaa cgcaactaaa ttagctcaag atatagaagg aaacgttgat
     4921 gtctctgtat tcgtagatat cggtacaaaa gacgaagaga tgaaaaagct agaaaaagaa
     4981 ttgaatgact tagatcatgt taaaaaagtt gaattttcaa gcaaagaaca ggaattgaaa
     5041 aaaatccaaa acgaaatggg tgattcctgg aaattgtttg aaggtgacaa taacccgtta
     5101 tatgatgtgt atgtagtaag tgctactgat ccttcttata caaaacaagt agcagaagaa
     5161 gcagcagatt tgaagaatgt ttctcgttct gattacggtg gagcttcctc agatcggatt
     5221 ttccaaatcg ctggtgcagt tcggacatgg ggattagttg cagcggcatt gctgctgttc
     5281 gtagcgatgt ttctcatttc gaacacgatt cggatcacga ttttgtctag acagcgtgaa
     5341 attcaaatca tgcgtttagt cggtgcaaaa aatggatata ttcgctggcc gtttttcctt
     5401 gaaggtggct ggatcggtct gatcggtgcg attcttccga ttttgatcat cacatttggt
     5461 tatgcatggt ttttccaatt gatcaatcca tcattattac gttcccatta ttcattgatt
     5521 catccacaaa atatcgtttg gaaaatcaat cttttaatgg tcggcattgg tgtgatcatt
     5581 ggttcacttg gctcgatcat ttctatgaga cgtttcttga aattctaata ccacaatata
     5641 aataaaatga gaaagttgga cagtttcgtt ccagctttct ttttttattg gctaggagaa
     5701 tagaaggaag cggctttttt ccctttactt taaaaaacaa cttgggtatt cttaagttgg
     5761 tagaagaaga ggtgaagccg tgaaaattat cgttgacaat ttttttacga tccttttgat
     5821 tatgaatatt ttgctttcct ttatcatcgt ttttcgagaa agaaaggaaa ctgctcaaac
     5881 atgggcatgg gtgctcgttt tgatgttcat tccagttgta ggatttattt tatatatttt
     5941 tttaggaaga gggatttcca aagagaaaat ctttgatttg aagatccaag ggaaaatcgg
     6001 taagaacctg gaaattgaag aagacaaaca ggcattgatg cgagggcttt atcctcatcc
     6061 gcctactgga caagtagatg tgaaacaatt gatctatatg ctcacggtat ttgaaagtac
     6121 gctctatacg actaaaaatg aaatcacttt atttacagat ggtcgtgaaa aattcgatgc
     6181 gctgattgaa gatatcaagc aggcagaaga ccatatccac ttccagtatt atatttatcg
     6241 cagtgatgca ttaggtgaag aagttcgaga tgcattgaca gaggcggcaa gacgaggggt
     6301 aaaagtcaga gtccttcttg atgcatgggg ttccacacaa gtttcttcca gcttttttca
     6361 gaatttgaaa aaagcaggcg gagaagtcgc atttttcttt cctctatttg ttccgtatat
     6421 taatcctcgg atcaattatc gcaatcatcg taaaatcgta gttattgatg ggaaaatcgg
     6481 atatacaggt gggttcaatg ttggaaatga atatctagga ttggtaaaga aatttggtta
     6541 ttggcgagac aatcatttgc gtatttacgg agaagcggtg tataccttgc aaaaccgttt
     6601 tttgatggac tggaattctc agcatacaaa agaagtaggc tattctccca aattttttcc
     6661 gtccattcac tctactggtg atatagctgt tcaaatcgtg acaagcggac cagataccga
     6721 acatgaacaa atcaaaatga cttatttgaa aatgatttcg ttagccaaac gggagatatt
     6781 gatccaaacg ccttattaca taccggatgg atcgattcat gaagcactga agttggctct
     6841 tctttcaggc gtaaaagttc atatccaaat acctaacaaa ccagatcatc ttctcgttta
     6901 ctgggcaacg tattctttcg ctgcagagct aatcgagtat ggagcaagga tcgaaacata
     6961 tgagaatgga tttattcatg caaagacgat gattatcgat ggtggcattg tttcagttgg
     7021 ctcagcaaat atcgatgttc gttcatttcg cttggacttt gaggtcaata cactggttta
     7081 tgatgaacga atggcttcac gtgtaagaaa agcttttttt gaagactcga aaatttctac
     7141 gcatctcaca aaagaaatgt atgaaaaccg aggaataatc atcaagatga aagaaggatt
     7201 agcaagattg atttcgccgc tcctttaaaa cataaaaagg acatgagaac catcaacaga
     7261 tggagatctc gtgtcctttt ctaacggggc catttctgag agtacgtcag aaatggagaa
     7321 agcgtctcgc atgagcgaaa ttaactttgg ggtatctctt gttttttggg gaaagcaaga
     7381 aataagctaa tatatgctat taaaagagac acatttcaaa gccagtatag catagaaact
     7441 tttaatgaga tagttttttt tacaattatg agaatttatt ttgttattta atgattttga
     7501 ttcgttttca tcaagtaatg aaaatgataa aataaacata ctttaggatt aaaggagatt
     7561 tctaatgaaa aaacttaaat tattcttacc aataatagga ttagctattc ttttatcagg
     7621 ctgttcaaag tggattgatc gaggagaatc cattacggct gttggctctt ctgctttaca
     7681 gcctttagta gaaacagttg ctgaaactta ccagacagaa aatcctggaa aattcatcaa
     7741 tgtacaaggg ggcggaagcg gaactggttt gtctcaagta cagtcaggag cagtcgacat
     7801 cggaaactct gatttgtttg cggaagaaaa atcggggatc gatgcctcag cattagtcga
     7861 tcatcgagta gcagttgttg ggatcactcc tattgtgaac aaggatattg gcgtaaaaga
     7921 catcagtatg gaaaacctga aaaaactatt tacaggcgag atcaaaaact ggagtgaagt
     7981 cggtggaaaa gatcagccag tagttatatt gaaccgcgct tcaggaagcg gaacccgtag
     8041 cacgtttgaa aaatgggtat tggacggaga aacagctgtt caggcacaag aacaagattc
     8101 aagcggaatg gtgcgccaga tcgttgccga cacacccggt gcaatcagct atgttgcttt
     8161 ttcttatgtt tccgatgatg tagatacgtt gaatgttaac ggtgtagaac cgacagatga
     8221 aaatgtgaca acgaacaaat ggacgatttg ggcatatgag catatgtaca caagagatca
     8281 tccaaaaaaa ctgacaaaag aatttttaga ctatatctta tctgatgaag tacaagataa
     8341 catcgttgga gaactaggtt atatccctgt ttctcatatg aaagtcgaac gtgattggca
     8401 aggaaatatc gttaaagagt aatctttaca caaaatttac aaacttagct aaacttttac
     8461 atgttattaa aaccaaattg atgttcaatt tgtacactga gtgagtatgt taaacctgat
     8521 taagggggag tcatctgtgg aagatgtgaa aaaagtatta ttaacaaaat caaaacgttc
     8581 aaaaatggaa cagcgtggaa aattcatcag ttttttatgt atcgcgctga tcgtgttggt
     8641 tgtattatct attttttatt ttgtagctag taaaggattg gccacctttt ttactgataa
     8701 gatcaatgta tttgattttc tgtttggtac agattggaat ccaagccaaa tcggagcaaa
     8761 tgggaaacca atggtagggg cattgcctat gatcacaggt tcgtttattg tgaccttttt
     8821 atctgctatc gttgccacgc catttgccat tggtgcagca gtattcatga cggagatctc
     8881 tcctaaaaac ggaacgaaga tcttacagcc ggtcatcgag ctgcttgtag gtattccttc
     8941 tgtcgtttat ggttttatcg gtttatcagt tatcgtgcct tttgtcagaa gtatttttgg
     9001 cgggactggg tttggtatct tagctggtac atttgtgttg ttcgttatga tcttgccgac
     9061 tgtcacaacg atgactgttg atgcattaaa ggcagtgcca cggcactatc gggaagcttc
     9121 attagcgctt ggtgccacaa gatggcaaac aatctacaaa gtcgtgctac gagcagccgt
     9181 gcccgggatt ttaacagcag tcgtttttgg tatggctcgt gcgtttggtg aagccttagc
     9241 tatccaaatg gtcatcggta atgcagcatt gatgccaaca ggtcttacta ctcctgcttc
     9301 tacattgacg tccatcttaa caatgggaat cggaaataca atcatgggaa cagttgaaaa
     9361 taatgtgtta tggtcattag cgctgatctt gctattgatg tcattattct ttaatatcgt
     9421 gatccgtatg attgggaaga aaggagagct gaaataatga acgcaaaacg ctcagataaa
     9481 attgctacag gtgttttata tatagtttcg gggatcatcg tattgatttt agcagcttta
     9541 ctactttata tcttagttcg gggaataccg cacatttcat ggtccttctt gaccgaacct
     9601 tccaaagcct accaagaagg cggtggaatc gggatccagc tatttaactc gatttatttg
     9661 cttttgatca cgatgatcat cagttttcct atttctttag gtgcgggtat ctatctttca
     9721 gaatatgctg gaaaaaactg gctaacagat gtgattcgca cgtcgattga aatcttgagc
     9781 tcgttgcctt ctgtcgttgt cggtttattc ggtttcttgg ttttcgttat tcaattccag
     9841 tatggtttct cgattatttc tggtgcattg gctttgactg tattcaactt gcctcttttg
     9901 actagaacag ttgaggagtc tttacaagcg gtccattaca cacaacgaga agcaggattg
     9961 gccttaggtt tgtcacgctg ggaaacagtg ataaaagtgg tggttccaga agcgacacca
    10021 gggattttga ctggtgtgat cctaagttct ggaagaattt ttggtgaagc agctgcattg
    10081 atctatacgg ctggacaaag tgcacctgcg ttagatttta cgaactggaa tccattaagt
    10141 gtttcaagcc cgatcagcat tttccgtcaa gctgaaacat tagctgtcca tatttggaag
    10201 atcaatacag aaggcacgat gcctgatggt gtttctgttt cggctggcgc ttctgccgtg
    10261 ttgattattg ctgttttact gttcaacttc ggcgctcgtg cgattggcaa acgattatac
    10321 cgaaaaatga cttcagccta aggagaagaa gcaaaatgaa aaaatataac tggaatgaaa
    10381 caaatgtcat caccatgcca aaagagaaag aagtagcact atatacggat gatctacatg
    10441 tctggtatgg cgacaatgaa gcaatcaaag gagtggatct ggaatttgaa aaaaataaga
    10501 tcactgcact gattggtcct tccggctgcg gaaaatctac gtatcttcgt tcgttgaatc
    10561 gaatgaatga tgggatcgct aatacgaaaa tcactgggaa aatcatgtat caaggcgtag
    10621 atattaatgc gcctcaagtg gatgtttatg agatgcgcaa acggattggc atggtttttc
    10681 aacgtcctaa tccgttcagc aagtcgattt atgacaatat tacatttgct ttgaaacagc
    10741 acggcgaaaa aaacaaaaag aaattagatg aaatcgttga aacaagcttg aaacaagctg
    10801 ccttgtggga ccaagtaaaa gacagcttgg acaaaagtgc cttggcttta tctggcgggc
    10861 aacagcaacg tttatgtatt gctcgtgcga tcgcgatgaa acctgatatc ttgctgctag
    10921 acgagccggc aagtgctttg gaccctattt cgacaggaac ggttgaagaa acacttgtaa
    10981 acttgaaaga agactatacg atcatcatcg tgacgcataa catgcaacaa gcagctcgta
    11041 tcagcgacta tactgccttt ttctatttag gaaaagtaat ggaatatgac aaaactaaca
    11101 agatatttac cagaccaaaa attcaggcaa ccgaagatta tgtgtccggt cattttggtt
    11161 aagacggagg cctcaacatg acaaaagaga ttatttcatc taaagatctt catctgtatt
    11221 atggaaagaa agaagcacta aaagggatcg atctaagctt caatcaaggg gaaatcactg
    11281 cgatgatcgg tccttctggt tgcggaaaat ccacttatct gcgttctttg aaccggatga
    11341 atgacctgat tccgaatgta acgatcaccg gaagtgtttt atataaagac aaagacatct
    11401 atggtccaaa aacagatgtt gttgaactaa gaaaagaaat cggcatggta ttccagcagc
    11461 caaacccatt tcctttttct atctatgaaa atgtcatcta tggattgaaa ttaaaagggg
    11521 aaaaagataa aaaagtcctt gatcaagtag ttgaagaaag cctgaaggca gcgtctgttt
    11581 gggatgatgt gaaagacaaa ttgcataaaa gtgctttatc tttatccggt gggcagcagc
    11641 agcgtgtatg tatcgcacgt gttttggcag ttaatccgga aatcatctta ttggatgaac
    11701 caacaagtgc gcttgatcct gtttctactg ggaaaatcga aagtatgctg ttagaattaa
    11761 gagagcggta tacgatgatc atcgtgaccc ataatatgtc tcaagcttca cgtatttcag
    11821 ataagacggc attcttttta gatggtcact tgatcgaata caatgatacg aagaagatat
    11881 tcatgaatcc agaaaaacaa gagacagaag attatatttc aggtcgattt ggataaggag
    11941 gaaacggaat gctacgtaca caatttgaag aagaattgct gaatctccat aatcagttct
    12001 acgaaatggg gatgatggtg agcagcgccg tgcacaagtc agttcgtgca tacatcaaac
    12061 acgataaaat cttagcccaa gaagttatcg aaaacgatat aaatatcaat aacatggaaa
    12121 cacgcttgga gaagaaaagt tttgaaatga tcgcattgca acagccagtt acaactgatt
    12181 tgcgtatgat cattacggtc atgaaagcta gctcggattt agaacgtatg gccgatcatg
    12241 cggtgtctgt tgctaaatcc acgattcgcg taaaagggca gacgagaata ccggaaatcg
    12301 aaaaagagat ctccgatatg tccgattatg tgaaaaaaat ggtggacaac gtcctagttg
    12361 cttatgtcaa aacagacgaa aaagacgcac gtacgatcgc caatatggat caaagagtca
    12421 atgactattt caatcgaatc tataatgcaa caatcaaaaa tatgcaggaa aatcctgaga
    12481 cagtcatcag tggaacagac tacttgaatg ttgccagtta tctagaacgg atcggagact
    12541 atgtgacaaa catctgtgaa tggatcgtct acttggctac agggaaaatc actgagttaa
    12601 atacgaacca caatgagatt ttctaaactg aagctgtgat tatgccgttt gtttaggaaa
    12661 agaggttgtg aaatcagcgg ttgtgaaaaa gctgttctgc atcaagtaat aagaacagtc
    12721 aaacaaaaaa tagctcctca tatttttcgt ttggctggac ttattaccgc agatgcaagc
    12781 ttttgaacac cgtttattcg ggaaagggtt tgtgacaaaa catgtcacaa acccttttca
    12841 tcatttcata gaaaggataa agaatgcaaa aaaaaattag catcatcact atatttttta
    12901 tttgtgtgct tacttcatgg gttattcagc atcaagccgc tttatatgaa gtacctgtca
    12961 tcgagataga aaaagtacga ataaaagagg atcatcaatt gattacagga aaactgatga
    13021 acacggatca aaaaggagaa tcgatttatt tatcggttcc ttatcaaaaa aatcaaatag
    13081 aaacagcaaa tataaaagcg agacaaatgt atctagtcca aatgcatgga gatgaatggc
    13141 agctagtagc aaaaaaaaat gatggctggc ttttcttctt cacaagtatc ttcattggcg
    13201 ccatgttgct tattggtgga aaacagggtc tatttgcttt aggaagtctc atcatcaata
    13261 tcgttttact tttacttttg ttgctcatct ttactaaaac agaagggatt tctctattaa
    13321 atatatctat cctgttcgtc gttataggga tgattattag catattggct ttagatggat
    13381 ggaatagaag cagtataatc aaaatttcag ctgcagttac gagtgttttt ttagcatttt
    13441 ttatttgtct tttgacaatg aatcattgga aagaccaagg actgcgctat gaggaactga
    13501 attatctgac acgaccgtat cgttctgttt ttctttctag cgtactgatt ggaacagctg
    13561 gaggaacact cgataccgtt atcacagtca ttgcgacatt agaagaattg actaagcgac
    13621 aaccagaaat aacagcgaaa cagttatggc tttcaggaag gcaagtgggt cgagatgtga
    13681 ttggctcgat gaccaatatc cttttgttcg tctatatcag tgggtcagtt ccatcgcttc
    13741 ttttatattt aggaaatcaa tggtcgttca aagaaacgat agaacagcat ttatcattgg
    13801 aatttttacg cgtcattgct ggcagcttag gaatagtatt atcgatccct atctcggtcc
    13861 tcttttttct gactgtaagg aggctgaaac gatgaatgta cttattatac ttgttgggat
    13921 tttagcaatc agcgtgctac ttattggcgg tacgcaaggt atgtatattc ttttaggctt
    13981 attcatcaat ttagggatct ttttcctgtt gttattcggt tatcatcaga agtggccgat
    14041 actggcattg tcggtcatag gatttttatt gattgctgtg gttatcttat tttttatcaa
    14101 cggttataat ctaaaaatgc gtgcagcttt tgtgagtata ctgatctttt tattttgttt
    14161 cctactattg cttcctatca ctgatttttt agcaatccaa ggttttacat cggtagaact
    14221 agaagaatta tctggcttag ataagacttt agcgattgat tttagattac ttacgagatc
    14281 gttgcttctg attagtctta gtggtgctgt tttagatgcg agtgtagcaa tttctagtgg
    14341 gacattcgaa gtatatcagg caaatccgca attatctttt taccaattgc gccattctag
    14401 tttcgctatt gctaaaaaaa tattggcgtc aacagtaatg acacttcttt ttgcattcat
    14461 gggaagttct ttagcgttga tcctctggtt tattgattta gacattcctt ttcagcaagt
    14521 gatcaatgaa aaatcatttg ttctagaata tacgatggct attcttacca cattgtccgc
    14581 actacttgtt cttcctttaa cctgcgtgac tacagcatat ctctttacaa aaaagaaaga
    14641 acaactcaag atggagtaaa agttacaact taagtcctat gacattttta ctgaatcagt
    14701 gcataatatg gatgtaagga aaagcttgca aacaattttg cttaaggagg caatttccat
    14761 gaaagaaaga gaacgtattt tagatttagt gaaaaaagga atcctttcga ctgaagaagg
    14821 cttagattta ttagaaagca tggcaactga aaaagacgaa aagcaaatca aaaaagaagc
    14881 agacaaggta actgctagtc ataaagaaaa agatcaggca agtcaattga tcgataaact
    14941 tgaaaacggc gaagaagaaa tttctgagcc agttgatcca aaggaaagag aaagacaaga
    15001 tcaagaaaac ttagaaaaga tcttagatga actagcaact gaagcgaata aaacttcggc
    15061 gcgtctagat gaagtaaatg ctcaattcgc tgacaataag gcagcacgca atgagaaaca
    15121 ggaagcattg atgcagctga atacaaaaga agaattaggc gagttgacag aagaagaatt
    15181 agcacagcgt cagacgttag aagcagaaat caaagaatta gaagctagtg gcgatacact
    15241 gttagaagaa caattgaaat tagaagcaga attaaaagat atccgtaaga atcaatggtc
    15301 tgagaaaaaa gaaacgttta ctgataagtt tgaattgcca gatgattgga aagatcaagc
    15361 aacagataca ctgaatcaag taggcgaaaa aatgtcagaa gctggatcac agttaggcaa
    15421 attcttgaag aaaacattcc aaactgtttc agaaacagtg aatgacaaca tggaatggaa
    15481 agatgtcagc ttacgtgtcc ctgggattgc gacaacgaaa tttgagcatg aattttacta
    15541 tgaagctcct gcagcaagta tccttgatat caaggcagca aacggaaacg tgacgttaaa
    15601 aacgtgggac agcaacgatg tgaaagttga agctaagatc aaactttacg gaaaaatggg
    15661 tgctgaacca tttgaagcat tctctgaacg gagccagatt gaggttaatg aagatcatat
    15721 ctccttccaa attccaaata aacgtgtgcg tgcagacctt gttttctact tacctaaacg
    15781 agtatacgac cacgcagcta ttaaacttct aaatggcaac atcatgattg aaacattgga
    15841 agctaaagat atttatacaa aatctacgaa tggtaacatc atcgtggacc aattaactgc
    15901 aacgatgctg gaagtagaag gtgtaaacgg caatatcgat attcgaaacg ggaacatctt
    15961 agattctatt atcgaaacag taaatggtac agtgacattt ggtgcgacag cagaaaacct
    16021 ttctgtgtct ttggtaaatg gtgatgtacg tcttacgatt aaagaagata atttgaaaaa
    16081 agtagaagca agttcagtga acggaaatgt caaagtcgct ttaccagatg gcatcggttt
    16141 ggaaggacat gctaaaacaa gtcttggaag tatcaacagc cgtctgtcca attacgaagt
    16201 agttcgtgag aaaaaagaac ggacaaacca aatgttgcaa ttccgtcgtg tttcagatgg
    16261 tgaaatcgcg caagtgcaac tttcaacgac aacaggaagt atctatttaa aagatacaga
    16321 taaataaaga ggttgtgaaa gagatgttca gccttgagca ataagaagcg attttgtaaa
    16381 atagcttccc ctattttaca aaattgtgcc ttattgccga tagtctatct cttgaacacc
    16441 gtttaccaag agattatgaa cctgccaatt atcgccgagt cacaaggaat aatttcagaa
    16501 aaagctcgtc acgttttatg aatatggtaa tttgtgaccg agaattttgc agaaagacac
    16561 cgattaagaa gaaggttgtc acaacgattt tcttcattta aaatagtaga acagaggtga
    16621 gacatgatga aaaaaaagtt gacaaaatct aataaaaatg ttgttttgac agggacttta
    16681 gcaggaatag gagaatacat cgggattgat ccgactgtta tccgtgtgct ttatgtattc
    16741 ctgagcttag ttgcttttgg aagtccaatt attttataca ttttattagc tttgattatc
    16801 ccatctgcgc gttctgcacg aacaaactat ggacataaca atgcatatta tgaaaaaaac
    16861 aattatcgtg aacaaactcg tgaacaaaca aaaaaacgca aagaagcgga aaaaatcgat
    16921 gatgacgaat ggagtgactt ttaatgtcgt actttcaacg tattttagtt aatacgttaa
    16981 cattcatatc attggctgtt ctttttcctg cgatggtcca tgtgagcagt atttggacgg
    17041 ccgttcttgc cagcttcgta ttgtctgtgt tgaatatgtt tgtcaaaccg attttgacga
    17101 tactgtccct gccctttaca ttagtcacat tgggattgtt tacgtttgtt atcaatgcag
    17161 cgattcttaa aatgacctcc ttttttgtgg gagcagaaca ttttagtttt tcttcattcg
    17221 gtgcagcgtt gttagtagct atcttgatgt cgcttgtcaa tgtaattgtc agcgaacata
    17281 acagtagaaa ataaaagaaa gctgtgccga actatcggcg cagttttttt atttagaatc
    17341 aggaatgcgt tttctattac attggtaatt aaataaaaac gtttttttta attggtagta
    17401 cttttggcta gacaatgata aaatgataga gaacactcta atagaaatga ggtagcatga
    17461 atgtcagaag ttgtaaaagt tagccaatta gtgaaaaaat tatctttgga aatcgtgaca
    17521 ggcgacgaga aaagcttaga ccgtgtcatc gtaactgggg acatctcacg cccaggacta
    17581 gagttgactg gttattttaa ttattattcc cataatcgtt tacagctatt tggcagtaaa
    17641 gaaatcagtt ttgcggaacg gatgatccca gaagagcgtt tgatcatcat gagaagatta
    17701 tgtagtgaag atatgcccgc atttattatt tcaagaggat taccagctcc agaagaaatg
    17761 atccaggcag caaatgaaaa tgggatagct gtactgcgtt ctcccatctc aacttctcgt
    17821 ttattaggag aattatccag ttatttagat ggtcgccttg cccctcgaac aagtgtccac
    17881 ggtgttttag tggatgttta cggattaggt gtactgattc aaggtgacag tgggatagga
    17941 aaaagtgaaa cagcgttgga gttgatcaaa cgcggccatc gattgatcgc agacgatcga
    18001 gtagatgttt atcagcaaga tgaattaacg gtgatcggag aaccgcctaa aatcctggaa
    18061 catctgattg aaatccgagg aatcgggatc attgatgtaa tgaatctttt tggtgcgagt
    18121 gcggtacgtg gctctatgca agtccagttg gctgtttatc tggaagcatg ggcaaaagat
    18181 aagaaatacg accgtctggg ctctgaagac acgaccgttg aaatcgcgga agtgggcatt
    18241 ccacaaataa aaatccctgt caaaacagga cgaaacgttg caatcatcat tgaagtagcc
    18301 gcgatgaatt tccgcgcacg tacaatgggc tttgacgcaa cgaaaacatt tgaagaaaga
    18361 ttaagtcgct tgattgaaga aaactcaggc aacgactagc aaggagtgac aatatgttag
    18421 cacaaatcaa tcgagttgct tttgagcttg tagggattcc tatctactgg tatgcattga
    18481 tcatcgtatc aggtatcatt atcgctatgt ggcttagcag cagagaggct gttcgggtag
    18541 gattaaaagc agatgatgtg acagatttta tgttgtgggg attgcctatc tccattattg
    18601 gcgctcgctt atattatgtt ttatttgatc ttccccagta tatagctgat ccaatccaaa
    18661 tattcaatat ccgttcagga ggcttagcta tttatggcgg actgattgca ggcgcgatca
    18721 cgctgtattt ttttactaaa tatcatttta tttctttgtg gactttttta gatatcgctg
    18781 caccaagtgt attattagca caggcaatcg gtcgttgggg aaatttcatg aaccacgaag
    18841 catatggacc agacacgacg cgaagcttct tagaaagtct gcatttaccg caattcatca
    18901 ttgataatat gtatatcgaa gggatctatc gtcaaccaac atttctttat gaatcacttt
    18961 ggagtttgat tggatttatt ttgcttttgt ttttacgaaa gaaaccacac cttttgaaaa
    19021 aaggcgaagt ccttttatgt tatctaatgt ggtatagttt cgggcgtttc tttattgaag
    19081 gattacgtac agacagtctt tactttttag gtgtgatccg tatttctcaa ttattatctg
    19141 ctgtgttatt tgtcggtaca ttgattctat ttatttggcg cagaaaaaaa ggaaatttac
    19201 cggattatga ccgctcatta ggaaaaaatc aacaaattat ctgattttta gagcgttaaa
    19261 aatgaaaaaa atttcaggag tggtaaaatg aattatagag tagcggtttt aggaccaggc
    19321 tcttggggta ctgctttggc acaagtcctc gccgaaaacg gacatgacgt tcggatttgg
    19381 ggacatcgtg cttcacaagt agaagaaatc aacacccaac acacgaatca acgttattta
    19441 ccagatcatt atctacccga ttccatccaa gcattcacca atatggaaga tgcagtaaaa
    19501 gacgcagatg cggtgctatt cgtcattcca acgaaagcaa tacgttctgt tgcaaaagaa
    19561 ctagtgccta aattgaatac aaagccagtg atcatccatg caagtaaagg attagaacag
    19621 ggaacacata aaaggatctc tgacatcttg ttagaggaaa tcccagcaga aaaaagaaaa
    19681 gctgttgttg ttctttctgg accaagccat gcagaagaag tagcaaaaca tgacatcact
    19741 acgatcacag ctgcaagtac agatgcaaaa gcagcaaaat atgtacaaga gctgttcatg
    19801 aataattatt ttcggatcta taccaatcct gatgtgatcg gtgtagagat gggggcagct
    19861 ttgaaaaata ttattgctat tggtgctggc gctattcacg gcttagggtt tggcgataat
    19921 gcaaaggcag caatcatgac gcgcggatta gctgagatca gccgtttagg tgtagcaatg
    19981 ggtgccaacc cgctgacctt tatcggatta agcggaatag gcgatctagt cgttacttgc
    20041 acaagtgttc attctaggaa ctggcgcgca ggcaacttgt taggacaagg gcagccccta
    20101 gaagaggtgc tagccaatat gggaatggtc gttgaaggtg tgaatactac ccaagcagcg
    20161 atggaactag cccaaatgat ggaaatcgaa atgcccatca ctcaaacaat ctatgaagtg
    20221 ctgtatgaac aaaaagaaat caaaacagcc gcaaaagaaa tcatgttacg tgatggaaaa
    20281 aaagaaaatg aattctcatt aacaattttt tgaaggagcg aatgtatatg aaagttaaaa
    20341 aagcagttat tccagcagca ggattaggaa caagattttt accagcaaca aaagctatgg
    20401 caaaggaaat gttgccaatt gttgataaac caacaatcca gttcatcgtt gaagaagcgt
    20461 tgaaatcagg tatcgaagac atcttgatcg ttacaggaaa agctaaacga ccaatcgaag
    20521 atcactttga ttcaaatatt gaattagaaa caaacctaag tgaaaaagga aagaccgaat
    20581 tattgaaatt agtagaagaa acgacagatg tcaacttgca tttcatccgt caatctcatc
    20641 caaagggttt aggacatgcc gttcttcaag caagagcctt tattggaaat gaaccatttg
    20701 tcgttatgct aggcgatgat ataatggaag acgaagtacc attgacacag caattaatcg
    20761 atgattacga acgtactcat gcttctacga tcgccgttat gcaagttcct catgatgaaa
    20821 cttcaaaata cggaattatc aatccaggag aagtattgga agatgggtta tacaatgtca
    20881 aaaactttgt tgaaaaacca gatccaagca aagcaccaag tgatttagct attattggac
    20941 gttacttatt gactccagaa atttttgatg tattgtccga gcaacaacca ggagccggaa
    21001 atgaaatcca actaactgac gcaatcgata cattgaataa aacacaacgc gtatttgccc
    21061 gtaaattcac aggtaaacgt tacgatgtcg gtgacaaatt tggttttatg aaaacaagta
    21121 ttgaatatgg tctaacacat ccagaagtag gtgcaccttt acgtgagtac atcctgtctt
    21181 taggtaaaac attagaagca gaaggaagca agatcgatca taatccaaaa ggaataacag
    21241 aaatcaaaga agaaaagaaa aaataaccct tttttctaac gagcttcagc tgctaattga
    21301 ataaaaagta gttgaagctc gtttttattt gtttaaaaaa cacgaaaatg ctatccttat
    21361 agaaaagaga gacaagaagg gagtttgatc atgtcaggag gagaaattgc aggattgatc
    21421 gcagcaatcg cctttgcgat acttgtcgtt tttatcgttc gtgtgttgtt gcaagtttct
    21481 aaaactttag aaaaagtaga tcagactgta gcagaagcaa atacgacgat cgaaatcgtc
    21541 acaaaagacg tagatctttt gtctagacaa gtagaaggct tactggtcaa aagtaatgaa
    21601 ctgctcttgg atatcaatgg aaaagtcgca acgatcgatc cattgttcac agcagttgct
    21661 gatttaagtg aaagtgtatc agaacttaat cattctagta aaaacatcgc gacgaaagtc
    21721 ggcggaatcg gtaaaacgac agctaaagcg acggttgccg gaaaagtcgg tgggacagcg
    21781 atgaaatttt ttaaaaacaa aaaacatact gaaacgacag gaggaaaata aaaatggcta
    21841 aaaaaggtgg atttttatta ggtgcagtag tcggaggcac agccgcagca atcgccgcgt
    21901 tattgttagc accaaaatct ggtaaagaac ttcgggatga attagctgcc caagcggatg
    21961 atttgatgga tatggcttca gattacacag atatggcgaa agaaaaatcg actgagttaa
    22021 caggtattgc aaaagaaaaa gcgcaagatc tttctcaaca agcaggtgat ctagcaggta
    22081 gtgtcaaaca aaaagtaagt gaatcagcag atgaagcagg aagtgaatct gacgatatct
    22141 tgttaaatct taaagaacaa tcagctgact tatctaatcg tttcaaaaaa acggcagaag
    22201 atatgaaaaa acctgcagat gaattaggaa gtattgctaa agatacttca gaagatatca
    22261 tgattgatgt aaaagacgct gctggtaaag caggagatac tgtcaatgaa ggaatgtcag
    22321 aagcaaaacc agttgcagat gactcaaaag aaatgatgaa aatggcaaaa gaagatgcga
    22381 aagaagctaa aaaagaaata aaagatacaa tgacagattc atctacaaat cactaaaatc
    22441 acaaatttat agaataaaaa ggtgggagcg gactagctct cacctttttt actcttattt
    22501 ttctaaaaca agtaattctt ttggtgtagt cgtgaatggc acacagccat cgcttgtcac
    22561 atatacacag tcttcgatac gtacccctac tttttcagga atatagattc ctggttcaag
    22621 agagaagcac atcccttctt cgattactaa gtcatttcct tctacaaggg aagggaattc
    22681 gtggacggtt gttccgatcc cgtgacctaa acggtgattg aaatattcgc cgtagccata
    22741 gctgttgatc acgtttcgtg cgatttgatc aagttcacct gctgtcacac ctggacggac
    22801 ggcttcttgt gcggcaagct gtgcttcaag agtgatgttg tagatttttt cttggaagtc
    22861 ggttggtttt tgataagcaa ttgtacgagt agcatcactg caatagccat tccaaacaac
    22921 gccaagatcg aataacacaa gttcattcgg tgaaatcttc gtatttcctg gtgtaccatg
    22981 agggcttgca gcatttgctc ctgcaaggac taatgtgtcg aaagacattt gtgaaacacc
    23041 ttgttttttc aattggtatt caatttctgc aatgatcgct tgttcagtca cgccttcttt
    23101 cactgcttta aagccaatct caaatgcaac atcggcccat ttaccagctt cgatcagttt
    23161 gtctttttcc tctagagttt tgatcagttg tagacgttgg atgatggaag ttagatcagt
    23221 gtaagaatcc gttcccgtca agatatcaga gatagcatcg aagcgctcga cagtcaaggc
    23281 gttcttttca atccctacat tgccaggctg accatagcga gcacgaagtt cttttccgat
    23341 gatctcccaa gggttttcgc tgtctaaata gccacggaca tcatacgccc aactactgtt
    23401 ttgagcatct tcaacttcca aagcaggagt gaaaaggaaa ggatcttgtt caagagggat
    23461 aaaaagagct agtacacgct catgaggatc actttcgtat ccggaaaagt aagcgatgtg
    23521 gccagggtcg ctgatataag ccaattcgac ttggtgttgt gccatccatt gacgtagttc
    23581 attgattttt acgttattca tttggcaacc tactttctaa attaattttg tattcaataa
    23641 ttgtaccact gatttattaa aagaccaacg ttctaaaaac tgaaaaaagt aaaaattttc
    23701 atgaaaacag agataaaacg gttgcaattc ttgagattat ttgatattct attttagaaa
    23761 tgtaagacgt attttcagaa aacatataaa atatgaatag gagaacacaa atggaaaagc
    23821 aaacaatcac tatctatgat gtagcgagag aggcaaatgt ttcgatggct actgtttcac
    23881 gtgtcgtaaa tggcaatcca aacgttaaac cagcaacaag aaaaaaagtc ttggaagtta
    23941 tcgatcgctt ggattatcgt ccaaacgcag ttgcgcgtgg cttggcaagt aagaaaacaa
    24001 caacagttgg tgtaatcatc cctgatgtca gcaatatgtt ctttgcttct ttagcacgtg
    24061 gtatcgatga tgtggcaaca atgtacaaat acaatattat cttagcaaat tcagatggca
    24121 acgaccaaaa agaagtcaat gtattgaata acttactggc taagcaagtg gacggcgtga
    24181 tcttcatggg tcaccatatc acagacgaaa tccgtggaga attttcacgt tcaaaaactc
    24241 ctgttgtatt agctggctct attgatccag atgaacaagt aggtagcgta aacattgatt
    24301 atgtatccgc aacaaaagat gcagtaaaca aattggcaaa aagcggcaat aaaaaaatcg
    24361 cttttgtcag tggtgcgttg atcgatccca tcaatggaca aaatcgtctg aaaggctata
    24421 aagaagcatt aagcgaaaat aacctaccat atagcgaagg attgatcttt gaagcacaat
    24481 acaacttcaa agatggtcta tctctagtcg atcggatcca taatagcggt gcaacagctg
    24541 tctatgtttc agatgatgaa ttagccatcg gtattttgga tggtttatta gaccgtggcg
    24601 tgaaagtacc ggaagaattc gaaatcatca caagtaacaa ttcactactg acagaagtag
    24661 ctcgtcctcg tttaacaagt atcacacaac cattatacga tttaggggcg gtatctatgc
    24721 gcctattgac gaaaatgatg aataaagaag aagtcgaaga aaaaacgatt atcttgcctt
    24781 atggaatcga agaaaaagga tctacaaaat aataaaagga caaccattca gaggttgtgt
    24841 gcctgccgtt taactctgcg ttacaaggag caatttcaaa aaacagcatc tcatgtttga
    24901 tgaatattgt gactcgtgat tcggagttgg caggagaaca ccgtttattt gggaaaaggg
    24961 gttatgacaa aattttgtta taatcctttt tttgtgtctt aaaaaagaga gaaagtggtt
    25021 gaaattacat ttatcgtata taaaacaatc cgtgtataga tgctgcattt tgttcaccac
    25081 catcaaaaaa ataagggact gtgacaatac tattgtcaca atcccttatt actgtgtatt
    25141 ctattaaatc aatcatcttt ctcatctgat tctttagttg cttgattcgc tcttgcataa
    25201 gctgaagcgg tgttccagta atctgtatag ttttcatcgg taccgccaac gccaaattta
    25261 aaggcgcttt tcttcggtcc atttttcgcc catagcgatt caactgtttt tcctggtgtt
    25321 tggatggatt ttttattgac agtaactttt ccaggtgttt gaccagtaaa tccagatact
    25381 tttttcttca tcacatcaga tgataattcg aatttctcat cagtgccaaa aatgtcaggt
    25441 tttgcttggt aagcttgatt gatcagattg gcaagataat tagccgaacg tatccttgct
    25501 ttgctgtcca ttccagtatt gtcatcgtgc cctgcccagc tactgatggt aatagacgga
    25561 gtagagacaa ttagccatga atctcggtat tcattggtag aaccagtttt tccgacccaa
    25621 tctgcttttc ctagatttcc gtttaagctt gagatggcat ctttgaatgg tgtagtgatt
    25681 tttgcattga tcacactacg catcatgtca ttcatgatcg atgccgttgc ttccgaatag
    25741 atccggacag agttgctttc gtgtttataa attacatttc ctgcgttatc tgtgatggaa
    25801 tcgatgatat agccttcttc atagacgccg ccgtttgcta aagcctgaaa tccgttggtc
    25861 tgttgaagcg tcgtgacatc tactgtacct aaaggagcag attcaacgcc ccaattgtca
    25921 tttgccgggt agttcatctt tgccaagtag tgctcgtaag catattgttt cgatccaccg
    25981 gaattcaaca catcttgata taagtgataa gccgggatat tgttggacca ttctagtgac
    26041 tcacggacgg tttggaaggt gttcgatcct tcgttagtag cattgacgat tttctcgcca
    26101 gcattttctc cttcttgcca agttgttgca taatctgata cacgggattc tgatccgata
    26161 agccccatgt cgattgcagg tccataaaca agaactggtt tgattgatga gccagcttga
    26221 cgttctgtat cgaaggcatg gttattttga ttctgactgt aattccgtcc gccaacgaat
    26281 ccgtagatgc ggccagttct gttatccatc aatacatttc cggtttctac ttgactgcca
    26341 gcaccatcat ctaacatgta tccataattt tcaacgccat tttgcaatgc agcatagaca
    26401 tctttatcga ttgtcgaatg gattgtatat cctttatttt ggatcgtttg ctgtgccttt
    26461 tgataataag cgtcactgac cgatgaatca gacatatcag cgttgtcttt ttcagccaat
    26521 tgttgtgcaa tgattcttgt tgcttcattc atcacagtat aatacaagaa ttctctgtca
    26581 gtctgttctg cgatttgttg tggtagaaag tcttttgtaa ggtcataggc ttttgcttct
    26641 tcgtattgtt ctttcgtaat ttggccttca cgatacatac tgaataaaac aaaatctttt
    26701 ctggcaaggc cggcagaaag atcttctttt agcgcgcctg tgttcgtgta tggactatac
    26761 gtgatcgggc tttggggtaa tccagcgata taagcagctt gcggcagcgt cacatctttt
    26821 gcatctacac caaagattcc ttttgcagct tcctggactc cagcaatgtt ttgtccctta
    26881 ttattacgac caaatggtga gacattcaaa tacgtagcaa tgatctcatc ttttgaaaag
    26941 tatttttcta cttgtgcaga aagaatgatc tcgtttgctt tacgtttgaa tgttgtttca
    27001 tctgtaagga tctgctgttt gactaattgc tgtgtcaaag ttgatccacc agaagagcca
    27061 ataccagtag cttcagatac taatgctcgt aaaacagctt taggaacgta accttggtgt
    27121 ttatcgaagt attcatcctc tgtgctgata attgcagttt tcaataaagg tgaaatctta
    27181 tcagatgaaa tagtcgtgcg catcagatct gtctggattt ttgatatctc tgtattatct
    27241 gcataaacaa tctttgacgt ttctgtaatg tttcctagtt ctgtctgcag tgctttttta
    27301 gtcggcaatt gtgtgtcttc gacgagatag gcaaaatagc cagcgcctat tccaatacct
    27361 agagctgcga acatcaaaag aagaacagta ataaaaacag tcaatgattg aaaaactcta
    27421 aaaataatct taggaacaaa ccatttttct ttttttcttc tattctgttt ttttcgagta
    27481 tttttgcgtg gcaaaagggt cacctcaact aatggtttta tttcgctaat tatagcaaat
    27541 aatagaacaa aaaaacagac aaggctgttt ttggcaggaa tttctttttt aaaagagtta
    27601 aaacgtgaga aaatgatctt tattataaaa gagttcttaa gcttttcttt agagaaaatt
    27661 tcagttacta tggagaacag ggcaaagaaa aatcaatcat tttctttgta tatcatctta
    27721 ccaatatata ggaattgtta gtaacaattg cctttcaagg aggaatccat ccatgttatt
    27781 aggctcacac gtcagcatga gcggaaagaa aatgctgtta ggagcagcag aagaagcagc
    27841 cagttatgga tcttcgactt ttatgatcta tacaggcgcc cctcaaaaca ctagaagaaa
    27901 agccatcgaa gagatgaata ttgatgccgg aaaagcgtac atggcagaaa aaggtctaac
    27961 aaatatcgtc gttcatgccc cttatatcat taatttgggg aatacgatca aaccagaaat
    28021 gtttcctttt gccgtccaat ttctgagaga agagattgtt cgtgcggaag ctttaggcgc
    28081 tactcaaatt acacttcacc caggtgctca tgtaggggca ggaacagaag ccggaattgc
    28141 tagaattatt gaaggcttga atgaagtttt gacaaaagaa cagacggcac aaatcgcttt
    28201 ggagacaatg gcaggtaaag gtacggaaat cggtcgaaca tttgaggaat tagcgcaaat
    28261 catcgatgga gtaaaattga atgaaaaatt atccgttact tttgacacct gtcatacgaa
    28321 tgatgccggt tataatatta aagaagactt ttcaggtgta atggaagagt ttgataagat
    28381 catcgggtta gatcggctta aagtactcca tatcaatgat tctaaaaatc cgcaaggttc
    28441 gcataaagac cggcacgcca atattggttt tggaacaatc ggattcgaca cgctgaataa
    28501 gatcgtccat gatccaatgt ttgacaatat ttcgaaaatc ttggaaactc cctatgtagg
    28561 caaagataaa aagaaagctt acgcaccata tggaaaagaa atcgccatgt tcaaagcgca
    28621 aacattcgat ccagaagtgt ttcctgagtt attagcagaa gaagtgatac tctaagattt
    28681 tctatctgac agcagcaaaa aaggaccagg cacattgcct tgtccttttt tgtttaagaa
    28741 acaaaggagt actttttgca gtctttttca tcatgcatct tctcccccct ctttttaaat
    28801 ttagacaaac aaggtatact ggtagaaaag taaaaaaacg aaaagtttca caagcaagtg
    28861 gcaaaacgtg attggaagga cgaaaagatg ctgaacactt taaaaccctt gatcaaccaa
    28921 ctaaaaaaga aacatacata ctttattctt ggcatagccc tattatttac aattattcgt
    28981 ttgtatttat atagtaaagc aatctatgga acagacatgt cggcaaccta tgatgaccag
    29041 ctgctgattc gctatgctca aaatattttg gacggtaaat ggctagggga gtatacgact
    29101 acaacacttt ccaaaggaat ctcctacagc ttatttttag tacttgcaca taaactgcat
    29161 ctttcttatg cagttttgtt cggcatgttc agtatttttg ccagtatatt ggttgcactc
    29221 gcgtttaaac cgattgtgaa gaacaagtat cttcttttaa gtatctattt ttattttttg
    29281 ttttctccga ttagttttac acatgaatat tccactcgaa catatcgtaa tgccctcgtg
    29341 attccggctg ttgagatcat tatcgcttgt ttattagcta tttattaccg caaatacggt
    29401 tctagcagaa aattgctgcc atggttttta gggctttctg tcgcttttcc tttcttttgg
    29461 ttcattcgcg aagattctat ctggcttctt ccttttactg tagtagcttt gggtatcagt
    29521 ttcgtccaga tcttgctagg gcaagacttt tctttcaaag aagtaaagaa gttaaaaaaa
    29581 cgactctttc ttctctcgaa acgggaatgg ctgaaacttt cattgttttt acttcctata
    29641 gttggctttt ccatcgtcta tcaatggatc gaatataaaa atgagacaac atacggtatt
    29701 gcaaccatca atgaccgttc cagtggagaa tttggacgtt tgatgaaaca actgatccga
    29761 atagatgatg aaacgaactt gaataaagaa aacagtgaga tatgggtctc acatgctgca
    29821 ctaaataaag cattagccgc atctcctaca ttccatactg tttctacccg tattgacgaa
    29881 ttatatacga ctcacgcgtg gactcaaggt ggaaaagtaa aagaattacc cggagatatc
    29941 atcttttggg cattgcgaga tgtggtaagc gaatctggtt attaccaaaa caatgcaaaa
    30001 gaaaccaatg atttttggaa aaaagtcaac caagaattag aagaagccta tcacaaggga
    30061 acaatcaaaa agaaaaaaga gttctatctg atgggatcag gagatggaaa gacgatgagt
    30121 gatctgccaa tcgtattcga tttccttcaa tcaggatacg cttatgcatg gcgatataaa
    30181 gatttccatc aaggaggaaa ttatagtttc ggaacgcaag aacaagtcaa acaggctcaa
    30241 gaattattaa accttccgct aatggagaat tggatcgata gtaatgaacc gagaacacct
    30301 aatttccaat taacaaaatc agcaaaagtc gcgaatgtca tcataaaaat ttaccaagtt
    30361 ctggctattc ccgtgctgat tgcttcaata gcagggatat tacttatgat actaggaacc
    30421 gtatttgcaa aagctgatcg tgcctattat agttcctctt tgattgtggt caccggatta
    30481 atactgacac aattggtttt tcttttcggt gtctcatggt tttgttctta tgcgccagaa
    30541 aaaaaggact attttttaag tgtctacact ggtgcaggcg tgccattaac gcaattcatc
    30601 gtagtaacaa gcatgctagt tttcagtaaa ttaaatctga aaaaagcttt atcttctaaa
    30661 taaaaagacc cttggtagct agatttttaa cctaactatc aagggtcttt gtgtggaaaa
    30721 atcagttttt attcgatttc ttctaccgtt tcctgcaaaa gctgttcata ttttttgttt
    30781 cctttatata aatcaccaat cgtccatgcc aacaggagaa ggacaagaac aatgattaca
    30841 taagcgatgt gatcagccaa tgctagttga gcggaagtgg cttgctcgcc gaagaaactt
    30901 tcgatctgtc ctggtaatcc tcgtaagttc aagtaagtta gactaatcac agagaaccag
    30961 ccaagaagtt ttacgatgaa tgaattttta aatcggctac ccatctccgc ttggctgttg
    31021 gtcatcatca gtaaaggaat catcgaaaac ggcaacgcaa aagccaagaa cacctgggat
    31081 tcattcatta agttattcaa agcggcatgt tcttcgatcg ttccttttgt acttgtaaac
    31141 aaaacacaaa tcaatacagg aatcacagaa agcaatcgtg tgaccagtct tcttagccaa
    31201 atcgggatac gcatatggat gaatccttcc atgatgactt gaccggtcaa cgtaccagta
    31261 atagtagagt tctggccaga agcaagaagt gctacagcaa ataaagtgga caagatacca
    31321 gattttgcta cagcaatcaa aataccattg ctcatagctg atggatcaga taaagcttca
    31381 tacagaccaa aaaaggaagg atcttggaca gaaccggttt tgaagacagc gacacccatg
    31441 atcaatagca gtgcattgac tagaaaagcc attgacaact ggatattaga atcccaagta
    31501 gaaaaacgta cagcttgtgc tacatcttct tcgttttggt gatcgatctt ccgagtttgt
    31561 gaaactgctg aatgaagata taagttatgc ggcatgactg ttgcaccaat aatccctaaa
    31621 gctccagtca gcggagtttc gccgccgatg accggtgagt ctgagaatgt atgactgtta
    31681 gggataaagc cagcaaataa actgtgccaa tctgggttag acaagccaac ttgatagaca
    31741 aaaacgaata aaatgacgaa aattaagcag acaaccagtg cttcgatctt acgaaacccg
    31801 acttttgtca gtagtaagag aacgaaaaca tctaatacag taataaagac ggcaatcacc
    31861 aatggaatat caaaaagtaa gtagagggcg attgctgcac caatgacttc tgcaatatct
    31921 gttgccataa tggctaattc agtcaagatc cataaaatga cacctaatgt cttacttgtg
    31981 cgtgctcgga ttgcctgtgc caaatccatt tggctcacga ttcctaattt tgctgccata
    32041 tactgtaaaa gcatagcaat cagactagac atcaaaataa ctgacatcaa taaatattgg
    32101 aaattttgtc ctccggtgat cgaagtagac cagttacccg ggtccatata cccaactgct
    32161 actaacgcac caggtccaga gtaagcaaga agtgttttaa aaaaactttt cccctttggt
    32221 acatcaactg ttccatttac ttcagctaaa gataaaccat ttgtatgttc aataagtcga
    32281 tgcttatgaa attgtttatt ggattgatta ttcaagaaaa aaccaccttt cctatttatc
    32341 tacgattaca ttctacacct caaaaagaaa aaattaaaga aaaagattcg gtacgcctaa
    32401 ttttttttca tggcgcgtct tgctagatga cgaaagaaat tttgttctcc tctaaaaaaa
    32461 ccactatttt ttgcatgaaa ctaaagaata cgcctttctt ttttcaataa actttagtaa
    32521 aataagtcat tgagagcaat tcggaaatag aaaggagaga tttatatgtt atcaacaggt
    32581 attgtcgtac ttattgctat tattgctttg ctaatcggcg cagtaggtgg ctttttccta
    32641 gcgcgtaaat atatgaaaga ctatttagaa aaaaatcctc ccgttaatga ggacatgttg
    32701 cgatcaatga tgatgtcaat ggggcaaaaa ccatctgaga agaaaattcg ccagatgatg
    32761 cagcaaatga agaaccaagg gaaaaaatag gttctgaccc aacgactttt tacgggctga
    32821 ttttttcagt ccgtttttta tttcgtaatt tgttagacta ttcagattat tcagcaaaaa
    32881 agacaagcac agacaatcct aggctcttga taaagacaaa ggaggagtaa aatgtcgatt
    32941 tttagaaaat taggctggtt ttttcgtcag gaaaagaaac attatttaat tggggttttc
    33001 tcgctattcg cagtggcctt ggtacagtta gttcctccaa aagtgattgg gatcatcatt
    33061 gatgagatcg ccgataaaaa tttatcaata aagatcattt tcgggtggat cttcctattg
    33121 attatcgctg cttttttaca atatcttttt cgttatatct ggcggacgaa tatttgggga
    33181 agtgcagctc gattggagaa agaacttcgg cagcagttat tcaaacattt tacagaaatg
    33241 gacaatctct tttaccaaaa atatcggact ggggatttga tggctcacgc aacgaatgat
    33301 ttgaatgcga tccagaatgt agcaggagct ggtatcttga cctttgcaga ttcagtgatt
    33361 acgggcggaa caacgatcat tgcgatgatt ttgtttattg attggcgctt aacactgatt
    33421 gcgctgattc ctctgccttt gctggccgtc acttcacgag tgctggggtc aaaactccat
    33481 gatgcttttc gtgattcgca agaagctttt tctagtatca atgataagac acaagaaagt
    33541 atcactggga tcaaagtcat taaaacattt ggacaagaaa aagaagatct agcggatttt
    33601 gaagaaaaga ttgaagatgc aattattaaa aacaaacgag tcaatttttt agactcctta
    33661 tttgatccat tcattacctt gattatcggt ctgtcttatg ttgcaacaat tattttaggt
    33721 ggaaagtatg tcttggaagg cacgatctcg atcgggcaga tggtctcatt tattagttat
    33781 atcggtatgc ttgtttggcc gatgtttgcg attggtcgat tgttcaacgt attggaaaga
    33841 ggaaatgctt cttatgatcg cgtcaatgaa cttttgcatg aaaagacgca tatcgtggaa
    33901 caactgggtg cagtgcagac cccggcaaaa ggcgagctga atgtagctat ttcctctttt
    33961 aattatccga aagaagaatc accagcatta gaacaaatca agtttgcgat ccaagaagga
    34021 gaaacattag gtattgttgg gaaaactggt gcgggaaaaa cgacgatcat caaattactg
    34081 atgcgtgaat acgatgatta tcaagggaaa atccaatttg gcggacgttc gatcaaagaa
    34141 tattcattga atgctttatt aggatcaatc ggctatgtgc ctcaggatca cttcttgttt
    34201 tcgatgacca ttcgagataa tatccgtttt tctaatccaa aactttcaga agaagaagta
    34261 gagcatgcgg cttctttagc atttatcaac aatgaaatca aggaattacc aaaaggttat
    34321 gataccttag ttggagaacg tggagtctct ttatctggcg gacagaaaca aaggatttcg
    34381 attgctcgag cattgatcaa aaatcctgaa ttattaatat tagatgatgc actctctgca
    34441 gtagatgcca aaacagaaga agctatcttg cataatttaa aagaaataag aaaagagaaa
    34501 acaactatca ttgcagctca ccgtttaagt agcgtgatgc atgcaaaaga aatcattgtt
    34561 gtcgatcaag ggaaaatcat tgaacgagga acccatcatg agctgcttgc actaggcggc
    34621 tggtatgaac aaatgtggga gaaacagcaa ttagaagcga agatagaagg aggcgaggcc
    34681 tgatggatga aaattatcaa tcggaatgga caaaatcgat tccacttaaa gaacagaaaa
    34741 agatcatcaa acgactgatg aagttcgcca aaccttttag aagaacgttc atcgttgcta
    34801 tcttatttgc gtttgctttg tctgtgatca atgtcctatt gccaaggatc atccaaactt
    34861 ttatggatga tcatctggct aaacagtcgg ctacgacaca agttattttg ttttttgctg
    34921 gtatgtactt atttggagtc atagtaaaaa gtatcatttg gtttttccaa tggtatttgt
    34981 attccatggc ctcattgaag acctatcagt atattagggt aaaattattt gaaaagctgc
    35041 atacactagg tatgcgttat tttgatcaga caccggcagg atcaaccgtt tctcgagtga
    35101 cgaatgacac agaaacgcta tttgaatttt ggtacgtctt tttgatggta ttgactggga
    35161 tctttgcagt cgtttcttca ttccttgcca tgtttcaaat caatggagaa attgccttgt
    35221 ggactttggt gtttttgccg attttaggaa tcgtcatctg gtattaccag aaattcagtt
    35281 ctcgtattta ccgaaatatg cgggaaaaat taagtcagct gaacacgaaa ttgaatgaat
    35341 cgatttccgg catgcgtatt atccagcagt ttcgccaaga agctcgttta gctaaagaat
    35401 ttgaacaagt gaacaatgag tatttagaca cgcgttatgc gatgatcaaa acgaattcga
    35461 ttctgttaag tccgatcatc aattttctat atgcattggc gattgcgttg gtgttgactt
    35521 tgtttgggat cgatgcgttg cattctcccg tagaagttgg actgatctat gcatttacga
    35581 cctatgtcca gggatttttt aatccaatgt ctcaaatgat ggactttttg agcatcttca
    35641 cagatgggat ggttgctggt agtcgtatct tgaagattat ggatacggaa gaatatgcac
    35701 cacaacaaaa ccctggagca gatcaaatga ttacttcagg taagattgag tttcgcaatg
    35761 taagcttttc ttatgatgga gagcacaatg tattaaacaa tatctctttt gttgctaatc
    35821 cgggagagac cgttgcatta gtgggacaca ccggaagcgg aaaaagctcg atcatcaacg
    35881 tattgatgcg gttttacgaa ttttatgaag gtcagatatt gattgatgat catgacattc
    35941 gagaatatcc aatggaagag ttacgtaaga aaatggggct ggtcttgcaa gatgctttct
    36001 tgttttatgg ggatatcgca ggaaatattc ggatgatgaa tccagctatc acagacgaac
    36061 agatacgcca tgcggctgag tttgttcaag caaacaaatt catcgatgaa ttaccaaaag
    36121 gatatcactc aaaagtgatc gaacatggtg ccagctattc tagtggacaa cgacagctga
    36181 tcacttttgc gcgaacaatc gtgactgatc ctaaaattct agtattggat gaagcaacag
    36241 caaatatcga tactgaaaca gaaggattga tccaagaagg attggcaaaa atgcgtcaag
    36301 gacggacaac gattgcgatt gcccatcggc tgtcaacgat tcgagatgca gaattgattt
    36361 tagttttaga caaaggtcat atagtagaac gcgggaatca tgaaacactt ctagcgcaaa
    36421 atggtttgta tgcagatatg tacaaactgc aaagcagtgg tatataaaag atgttgtgac
    36481 agtagaattt tgacctaagc actagagtga aaataaaaca tagcttctca tatttttcat
    36541 ctgtgagagt tagtgtcgta gtcaccagat ttaaaaaaag attcgacagc tagtcagaag
    36601 tgcctaatag ccactaagaa agcgttgaca aaagcatttg ctttcgataa tataaagaaa
    36661 acgatacaac ttggatagtg attgcctgat gcaagctaaa cctgatgagt ctcccatggt
    36721 ttcatggacg gctttttggg tttttctttt tgttttggat acagccctat acatcatgga
    36781 aaggagcaaa acatgctgat tgagaaagta ctgaataaca acgtcgtaat aaccagggat
    36841 gaaagaaatc aggaaatgat cgtgatggga aaaggtttgg cattcaaaaa gaaagtgggt
    36901 gacccgattt ttgactcatg catcgacaaa aaatttcagt tgacaaatga cgggctttca
    36961 caacagttcc aagaattggc acaagcgatt cctcttgagt acttagaaat ttcttgtgaa
    37021 atcattgaat atacaaaaga ggctctacaa gtccagttga atgattctgt gtatattgca
    37081 ttgacggatc atttgtatac ggctatcgaa cgtcacaaaa tgggaatatt tgtaccaaat
    37141 gtattgctgt atgatatcaa acaactattt cctaaagagt atgccatcgg gaaaaaaaca
    37201 gtgaagaaaa tctcggataa ataccacatc aagttatcag aagatgaagc cggatttatc
    37261 gcattgcatt tagtcaatgc acaaggcatt caaagccagc aagacaatac ctacctgttt
    37321 actataacaa tacaggatat tctaaatatc gtccgctatt actataagat tacatttgat
    37381 gaagattcag tccatttttt tcgattcgtc acacacttac gtttttttct gacacgcgtc
    37441 ctagatggag aaaaatcaga agtgggagaa gtttctgagg aattgtttca ggttattcaa
    37501 aaaaaatata aggatacgtt tggttgcgtt gagaaaatag cagacttttt agccgagacg
    37561 ttcaactacc agatgtccac ggacgaaaaa atgtatttaa cgatccatac tgcgcgttta
    37621 gtgcatgaga atcgttgtaa ataaaaaaag gaggataaat taacaagaac gtatgaaata
    37681 agggtagtga cattcagttg gctaaacctt ccactaataa attggaggga atagaaatgg
    37741 gaaaatacca agaattagcg agaaaaatcg tagaaaatgt cggcgggaag gaaaatatca
    37801 atggtttgac acattgtatc acaaggcttc gtttcaaatt aaaaaacgaa gaaaaagcaa
    37861 atgatgagat cttgaaaaat atggacggta ttgtaacggt aatgcgagcg ggagggcagt
    37921 atcaagttgt cattgggaat catgtgccag tcgtgtttga agaggttata aaagcaggaa
    37981 accttacttt tgatgaggct gtttcaacag aaaaaatgag accgtttgat atgcttattg
    38041 atggaatatc gggctgtttc cagccattcc ttgctatcct agctgctggc gggatgattc
    38101 gtggactgac agcattcctt gtcttcttag gcgcgtttga ccgcggttct ggcacatttg
    38161 ttatgtttga taatatcggt gattctgtat tccaatttat gcctgttatt atcggtttaa
    38221 cagctgcccg taaatttaaa gtaaatgaat tcgtagggat gttgcttggc gcagcattaa
    38281 tgaatcctag cttgtcgctg gaagctttga gtggtgcagc agaagcacca ctaacgacca
    38341 tattttctgg cactattttt gaagcaccta tttatcaaac agtattcggc attccctgga
    38401 ttgcgcgtaa ctacgcttct tctgtcattc ccattatctt tattgtgttg ttagctagcc
    38461 aaattcagaa accaattaaa aagttagtac ctgagatgat cgcgaatttc ttcgttccat
    38521 tcttcaccgt tcttattaca atgcctttag gttttttact cgttggacca gtattcacat
    38581 tcgcaactga tattttaatg gctggatttg aaacactttt agcactttcg ccagttattt
    38641 atggagcaat cgtaggcttc ttctggcaaa ttctggtgat gtttggtctc cattgggcaa
    38701 tcgtaccaat gggattgatg caattttctg tgaatggttg gcaaaatatt atgacacctg
    38761 ttgcagtagt gtcttttgga caaactgcag cacttaccgc actctacttt aagcttagaa
    38821 atccaaaaga caaagcaatt gcaataccag ccattgtttc tggtattgtg gggattacag
    38881 agccagctat ttatgggttt acattaccac gtaaaaaaat atttattttt acctgtgtcg
    38941 gtggtgcgtt agggggcgcg tatagtgggt taatgaattt aacttcttgg aatcaaggtg
    39001 gactaggcat ctttacaatt cccaactata ttagaccaga tggtgattta acagatgtga
    39061 ttaatgtatt gattgggatc gccattgcga tggtggtatc ctttacgctg acttttttct
    39121 tttggaagga tgaagcaggt gaaacagatg atatacagaa aaaatcaggt aaagaaattg
    39181 taaaaacacc gatacaagga caaatcgctc cactaaatgc agcaaaggat gcagcttttg
    39241 cacaaggaac actaggtcga ggaatcttga tctaccctga aaaaggagaa gtacgtgccc
    39301 cttttgacgg aacagtcatg accctgttcc cgacgaaaca ggcaattgga atggtttctg
    39361 aaacagggct ggaattgctg attcatgtcg gattggatac tgtgcagttg gaagggaaat
    39421 attttgaaag cttagtgcag caaggataaa gagtgaaaca aggcgatctg ttgctacgct
    39481 tcgacaaaaa gaaaatcgaa aaggaaggat acagtttaga aacacctgtg atcgtcacca
    39541 attacacgga ttatttggat attttggaaa accaagggga gacggtcggg ccagacgatg
    39601 cacttatcac cgcactgacc tgaacggtta ggtgaagaat ggactaggct taactattct
    39661 ttttattcca cttctttatt ttcaaaattg aaaggctctt tcatgatggc tgagctgata
    39721 gggcgtttat cgaatttttg accgacagaa attagatgga ctaaattctg ttgataattt
    39781 tctgcaaaaa cacaactata taacacgtct agaagataac aaattgatgt attgatcgta
    39841 aaattaccaa tttttgaata cagtcgctcg cgtgtcgtaa gtcgcaaagc ggctgtactc
    39901 attgcagata gcgttgaatc accgatactg gtcaaagcta aaattggaac atgattttgt
    39961 ttcaatattt ctgcggtacg aaggatcaca ttgttttcac ccgtataaga aatcagaatc
    40021 ccgcacatat cactcgtgca attgtacgct tcatagaatg attcaccaaa agtggtgaca
    40081 atcgtgacat ccattttgat gcgcttcatt ttcagcatga aatcttgaga aatcaaagta
    40141 ttcgagttac tggcgaaaat cacgattttt tttgcttgaa gcattagttg tttggctttt
    40201 tgcagttggt catgatgaat gagagaaagt gtatcatgaa tcgtcatctg ttctaaagaa
    40261 gccattttat ttgcgatcgt cataataccg tctgtggtgg aaaaaggaag attcgcatct
    40321 acgtcttgaa aattcccttc aagataggct gtttcagcta aaaaagcatt acgaaaactg
    40381 acccagccat caaaacccat tttttttgct acacggatga gtgtagaggg gtggacataa
    40441 catcgctcag caatcgcttg gatggtcatt tcgccaagtg ctggagaatc gcttaagaga
    40501 aactggatca cttcattttc tgaaggagaa aaggagattt ctttgatttt ttcacgtaat
    40561 aacatgtaga taccttcttc ttattttttt acgtaaatta taactttttt gaaaatgatt
    40621 tgtaaacgga tttatactat ataacttaaa atagacattt tttgacaaga tatttacaaa
    40681 aatccactag aaaacagtaa attttgtaaa tgttactgga aagaaacaga tttctattgt
    40741 ttgttttgtt tacaaaaaag ataatgaaag tgtaaaaaag taaaggagtg agaacatggc
    40801 aaaaggaatc aaaatcgcta cgattggtgg aggcagcagt tacacccccg agttgatgga
    40861 aggatttatc aaaagatatg aggaattacc gatacgagaa atctggctcg tagatgtaga
    40921 agaaggaaaa gaaaagcttg agatcgttag tcagatgtct cagcgtatgt gggatgcttc
    40981 tccgtatgaa gtcaagatct atgcaactct ggatcgggaa gaagcattga aagatgcgga
    41041 ttttgttacg actcagtttc gtgtcggtca attagatgca cgaatcaaag acgagcggat
    41101 ccctagttat tatgggatga ttgggcaaga aacaaatggt gctggcggga tattcaaagc
    41161 ttttcgtacc gttccagtcg ttttggcaat cgttgaggac atgaagcgtt tatgtccaaa
    41221 tgcttggctg atcaatttcg cgaacccaag tgggatggtg acagaagcag ttatcagata
    41281 tggcaaatgg gataaagtga ttggattatg caatgtgcca gtgatggcga tgatgacaga
    41341 accagcaatg cttggcaaga aaaaagaaga gctgatctac aagtttgccg gtctaaatca
    41401 tttccattgg cacaaagtag cagataataa aggaaatgac cgcacggcag aattgattga
    41461 tcgtttatac gatgaagaga atggattacc gaaaaatatc tttgatatcc cgtttttcaa
    41521 agaacaatta aaacaaatga acatgatccc ttgtggctac caccgctatt actatcgtga
    41581 agaagaaatg ctggaacatg ctttagaaga atatcaaacg attggtacaa gagcgcagca
    41641 agtgaaagaa acagaagcag agctatttga attatacaaa gatccagaat tagaccataa
    41701 acctgaacaa ttgcaaaaac gaggtggcgc ttattattca gacgctgcct gtgaaacgat
    41761 tgcttcaatc tatggaaata aagaaacaca gatcgtggta tctacaaaga atgatggagc
    41821 tgttcctgac ctgccggcag attgtgtagt agaagtcact gcctatgttg gcgcacaagg
    41881 agcgagaaat gtagcgtttg gttctcttcc tgctgctgaa agaggctggt tgcaagtaat
    41941 gaagaatatg gaattgctga cgatcgaagc agctgtgact ggtgattatg ggacagcttt
    42001 acaggcgttt acgatcaatc cacttatacg atcaggaaag acagcaaaac ggatcatgga
    42061 tgagttgttt attgcacacc agcagtattt accgcaattc aaggagacaa tcagccgatt
    42121 aaaagaagaa ggaatcgaag ttcaagatga actggcaaga gaattatcag gtaatacaca
    42181 tataatggag gaagtataat gggattcaga aaagattttt tatggggcgg tgctacagca
    42241 gccaatcaat gtgagggcgg ttatgatgaa ggtggacgcg gactagcaaa cgtagatgtt
    42301 gtgccaatcg gaaaagaccg ttttcctgtt atcaccggaa agaaaaaaat gtttgaattt
    42361 gatgaggatc atttttatcc agcaaaaatt gcaatcgata tgtatcatcg ttataaagaa
    42421 gatattgctt tgtttgcaga aatggggttc aagacttatc gaatgtccat cgcctggagt
    42481 cgtatttttc caatggggga tgagaaagag ccgaatgaag ctggcttgaa attttatgag
    42541 gatgccttta aagaatgcca aaagcacgga attgagccac ttgtgacgat tacgcatttt
    42601 gattgtccaa tgcatttgat caaagaatat ggtgcgtggc gttccagaga actcgttggt
    42661 ttttatgaaa atctgtgtcg agtcatcttc aatcgctata aaggacttgt caaatattgg
    42721 ctgacattca atgagatcaa tatgatcctt catgcaccat tcatgggcgc agggctgtat
    42781 tttgaaaaag gagaaaatga agaacaaatc aaatatcaag cggcacatca tgagttggtt
    42841 gcaagtgcca tcgcaacgaa gattgctcat gaagtagatc cggagaacaa agtaggctgt
    42901 atgctggcag caggagcata ttatccatac acttgcaatc ctgaagatgt ttgggcttct
    42961 agaaaatcag atcgagaaaa ttatttcttc attgatgtcc agtcacgagg agaatatccc
    43021 gcttatgcat tgaaagaaat ggagcgaaat ggcattcaga tcgaaatgga accaggggat
    43081 gccgcattgc tgaaagaaca tactgttgat tttatctctt tttcttatta tgcttcccga
    43141 gtttcgacta ccgacaacga actcttggaa cagactgcag gaaatatctt tgcttctgtc
    43201 aaaaatccat atctgcaagc aagtgaatgg gggtggcaaa ttgatccatt aggcttgaga
    43261 ataacgatga atgatattta tgatcgttat caaaaaccat tgtttattgt agaaaacggc
    43321 ttaggtgcag tcgatacgcc agatgaaaat ggttatgtgg aagatgatta ccgaatcgat
    43381 tacctggcag cgcatatcca ggcgatgaag gatgcagtag aactagacgg agtcgatcta
    43441 ttaggctata cgacttgggg atgtattgat ttagtatcag ctggtaccgg tgagatgaag
    43501 aaaaggtacg gattcattta tgtcgatcgt gataaccaag gaaatggcac attagcccgt
    43561 tcaaagaaaa aatcattcaa ctggtataaa aaagtaattg attcaaatgg agaaaatctt
    43621 tcgaacgatt gatcaatgat ttataaaagt ctattgtttt tcagcggatt tttcgagtat
    43681 aataaagcta ttcgagaaac gcaagcagaa caatagactt tttttcgcat tggctgtaaa
    43741 gtatgcttac ttgattaagt aaaggagaat ctacatatgt atgatgtaat cgttattggc
    43801 gcaggtcctg ctgggatgac tgctgcttta tatgcttcac gttcaaactt atccgtattg
    43861 atgatcgaac aaggtgcccc tggcggccaa atgaacaata cggcagaaat cgaaaattat
    43921 cctggattcg attcgatcat gggccccgat ctagcttata agatgtatga aagtgtctca
    43981 agatttggga cagaaaatgc ttatggaatc gttcaagata tcaaggatca cggcagccat
    44041 aaagaagtca tctgtgaaga taaaagttac gaaggaaaaa cagtcattat cgcaacagga
    44101 tgtatccacc gtaaattagg cgtacctggc gaggaagaat ttgctggacg aggcgtttct
    44161 tactgtgcag tctgtgatgg tgcgtttttc cgtaacaaac gtctagtagt catcgggggt
    44221 ggggactcag cagtagaaga agccatctat ttgacacaat ttgcttctga agtagtgatc
    44281 gtccaccgta gagatgaatt acgtgcacaa aagatcatcc aagaccgtgc atttgcaaat
    44341 gaaaaaattt cctttatgtg ggatacagtc gttgacgaaa tcgttggaaa cgaaatggta
    44401 gtgacaggtg tgaaagcacg taatgtcaaa accggcaatg aatttgattt agcagcagac
    44461 ggagtattca tctatgttgg actggatcca ttaactgcac cttttagaga agcaggtttg
    44521 acgaacgaag ctggctggat tccaacagac aacgaaatga aaacgaatat gccaggcgtt
    44581 tttgccatcg gagatgttcg tgaaaaagat ttgcgacaaa tcactacagc tgttggtgac
    44641 ggcggtattg ctggacaaca agtgtataaa tacttggagt ctttagaaga aacaacagca
    44701 taagtttaaa aagagtagaa gaacgggttc aattgttctt ttactctttt ttttcgcgtg
    44761 aaatttactg aatctgattt atgcgaacac gtccaacacc ttttgataaa agaatccttt
    44821 cttgatttaa gcgttttttg gtcctcatac tttcatatct aataagtgaa tgctatactt
    44881 attaagaacc atatttcaga aagaggtgtt attttcatgt cttgggaaca agtgtatgaa
    44941 caatgggtac atgaagaaaa tttagaagaa aacttaaaaa aacaattaaa tgatctgggt
    45001 gaagatcctg aaaaacttga agatgctttt tatgcaccgt tggaattcgg tactgcaggt
    45061 atgcggggaa tcttaggacc tgggatcaat cgaatgaaca tctatacggt aagacaagca
    45121 acagaaggac tagcacgttt catggataca caaggtgaag aaacaaaacg ccgaggtgtc
    45181 gctatcgctt atgactcacg ccatcagtca ccagaatttg caatggaagc agccaaaaca
    45241 ctagcacatc acaatatccc gtcttatgta ttcgaaagtc tgcgtccaac accagagctt
    45301 tcttttgcag ttcgtcattt gaagacgttt gcgggaatca tggtaaccgc atctcacaac
    45361 ccagcggctt acaatggata taaagtctac ggagaagatg gcggacaaat gcctcctgca
    45421 gacgcagatg cattgacgaa atatgtccgt gaagtcagca atccgctaaa agtcgaagta
    45481 ttatctgacg aagaagctaa acatagcggg ttgatcacga tcatcggaga agaagtggac
    45541 gctgcttatc tagaagaaat caaagcagtg acgattgatc gtgaattggt tgaaacaatg
    45601 gggaaagatt tgaaacttgt gtacacgcca cttcatggaa cagggaaaat gttgggcgaa
    45661 cgtgcgttga aacaagctgg attcgaacaa ttcgtactag ttcccgaaca agctgtggca
    45721 gatccagatt tcactacggt caaatcgcca aatccagaag aacattcagc ttttgaatat
    45781 gctatacgac ttggagaaaa agaaggagct gacttgctga ttgcaacaga tcctgatgca
    45841 gaccgtttag gcgcagcggt tcgtttgcca gatggttctt atgaagtatt gactgggaac
    45901 caaatcggag cattgtttgc tcaatatatt ttggaagcac atcaatcaag aggcacttta
    45961 ccagaaaacg cagcggtatt gaaatcaatc gtttccagcg aattgcctac agcaattgcg
    46021 gaacactacg gtgctaccat gttcaatgtg ttgacagggt ttaaattcat tgctgaaaaa
    46081 atccaacaat ttgaagaaga ccattcacat acttttatgt ttggattcga agaaagttat
    46141 ggttatttag ttaaaccttt tgttcgcgat aaagacgcga tccaagcatt gcttttatta
    46201 gcagaagtag cagcttacta taaaaaacaa ggcaaaacgt tgtatgacgg cttgcaaacg
    46261 atttttgaaa cctatggcta tttcgcagaa aaaacgattt ctgtgacaat gagcggacaa
    46321 gaaggttctg cgaaaatctc tgctttgatg gaaaaattcc gtaaagaagc accgacagaa
    46381 tttgccggag caaaagttat tcaaacagaa gactttaaag aattgacgag aacagaccgt
    46441 gaaggaaacg tagaaaaact aacaacaccg ccatccgacg tattgaagta tacattggaa
    46501 gaaaatggct ggatcgctat ccgcccttca ggaactgagc cgaaaatcaa gttttatatt
    46561 ggtgtaaaag gaagctctac agaagacgca gccgaaaaag tagcctctta tgaagcgatt
    46621 atcaaaaaga tgacagaaga ataaaaaact tgagactgat ggaaaaagtg gtaaacttta
    46681 gaagtcagtc ttttttcaag ttggaggtga atggattgcc agacacgcaa aaatcaaaag
    46741 tagagaaagt cagtcaatta ttcaaaatgt tgagtgatcc cactcgtctt aaaattctgc
    46801 tatatctgaa agacggggaa caaaatgtga cagcaatcac ccaagcagtg gaaatggagc
    46861 agtctgctgt atcgcatcaa ctacgtttat taagagaaaa tcatgtcgtc aagtctcatc
    46921 gcgagggaaa agcgattttg tatagtcttg atgattctca tgtactggat attttgaacc
    46981 agacactcaa acatgtggaa catcaataac gataggtgaa aatagataaa cactggagtg
    47041 tgacaacgaa gaaatttcgt tgtcacactc cagtgttttt taagaaaaag acaaaaatga
    47101 ttaatcgctt ttttctgttg tttcagttcc ataataacta tgatcttcta ggtctaaagc
    47161 attcaaaata agcgaagccg tttcttcaat agataaagat gccacattga tcactacaca
    47221 tcctagtttt tcataaagat cattcgcaaa atcgagttca gctctaattt tttcgatatc
    47281 ggaataagca gtatcagggt ttaatccgta agagcgcatc cgttctttac ggatattatt
    47341 taaaatatct gggttattcg ttagtcccac gattttttta ggatcgattt cccacagctg
    47401 tttgggaata tgtgcttggg gaatcaaagg taaattagca acttttaaat ttttatttgc
    47461 taaaaacaag ctcaaaggcg ttttggaagt tcgggatacg cctagcaaaa cgacatctgc
    47521 ttctaaaaaa ccacgaggat ctttcccatc atcgtatttt acagcaaatt ccattgcttt
    47581 gatccgtttg aaatagttct cattcaataa atggagggca ccaggttgcc gaattggctt
    47641 gataccagtt aaacgttcaa tttctgatat cggtggcgtc atcacatcga aactaaataa
    47701 ttgatgttct tcacaaaaag aacgtgttat ctcgatcagt tcttgattga ttaatgtatg
    47761 caggacaagt gctttttctt ctaatgcatc ttgcaatgcc tgccttaatg ttttttcatc
    47821 tgtcacgaac gttctgcgga ataggttgaa ctcaacggta ggatactgag ccatagtagc
    47881 ttgcgctagt tttgtcgcag tttctccagc agagtcggag atgacaaaaa aagtaacgat
    47941 ttctgtagaa tcggaagaca tggataaaac ctcacttgca ttttttttat gtttattata
    48001 ccatactcta gaatgcgtac ttcgtaatca ttttgatttg gaggaataag tcatgaaaaa
    48061 acagacattg atcgaacaat cattagaaac attgaaaaat aacggtttta aatatactaa
    48121 aaaaagagaa gcattgttaa cttatttagt gaagcgtaac cgctacgtat ctgctaaaga
    48181 agtttttgac tatatgaatc aggaattcaa aggggtaagt tatgatacga tttaccggaa
    48241 tctccatgat tttgcagaga tcgatttact ggaagaaacc gatttaaatg gtgaaatgaa
    48301 gtttcgtttt cattgctgtc agggggaaat cggccatcac catcatttta tctgtacagt
    48361 gtgcggaaca acgaaagaaa tccatatgtg tccaatgaat tatttcgaag aacagctagg
    48421 tggatgcacg atcgaagggc atagattcga gattttcgga agatgtgaaa attgtcaata
    48481 aggatttaaa taaaataaca tttgataatt taaaaaaaaa gcaagatttc cttgacggtc
    48541 aaaacagcat tagatataat atttacagga cagtcttgtt ttttgagata tatttcaata
    48601 acaattacgg ttacttttta agctcggagg gagggaatta acatgtcaaa aacagtcgtt
    48661 cgcaaaaacg aatcacttga cgatgctctt cgtcgcttca aacgttccgt gtcaaaagcg
    48721 ggtactttac aagaatctcg taaacgtgaa ttctacgaaa aaccaagtgt aagacgcaag
    48781 aaaaaatctg aagcagctag aaaacgcaaa aaattctagt tctgtgatga attggagttg
    48841 gtagtgtgtc actactaagt agattaaacg atgacatgaa agcagcgatg aaagcgaaag
    48901 ataaggaatc tttacaagtc atccgaatga tcaagtcatc tatacaaaac gagcagatta
    48961 aagaaggtca cgacttgaca gaagaagaag aactaacggt gttgtctcgc gaaatgaaac
    49021 agcgacgtga ttctttgcat gagtttgaag aagcaggacg tgacgattta gctgaaaaag
    49081 taaaaagtga aattgtaata gtcgaaaaat atatgccgga acaactttcc gacgaagaaa
    49141 ttcgacaact tgttcaagaa gcaatcactc aaactggtgc ttcatcaatg aaagaatttg
    49201 gcaaagttat gggtgcaatt atgcctaaag tcaaaggaaa agcagatgga aaccaagtga
    49261 atgcgattgt gaaagaacta ttacaatctt aattttatca tttaaactgc ggacagtgat
    49321 tgtccgcagt tttttgtgtt cgtaaaaaaa gaactaaaaa acagctagaa gaaagaataa
    49381 gattctttct tctagctgtt tttttcctgt ttaatatctc ttatgttaaa ttgtgtttga
    49441 tttggttatt cttctggtag ttcatttgct tcttgtttat accctgatag gcgataggcg
    49501 taataaaaga gtaagctgcc agcgtaacca agtaacgttg ggaccatcca gccaagtcct
    49561 aatgcagcaa aaggaacgtg atgatgataa aatcctagta agcttgctac gacagtttgc
    49621 tgactcacta atgcaggcga atttgccaac atatccaata cggctggaac ggcagaaaag
    49681 aacatcgtta cttgatagac aaatggactc ttttggaaga attttgctgt taaggaaagc
    49741 aagattaacg caagtgacaa tggatacaaa agcatcaata ctggtaaaga ccattggatg
    49801 atattatcca atccggcatt cgcaacgaca aaagagacaa aagtcgttaa ccgcagccat
    49861 gtcatataac tgactttagg gaacagttta tggaaatctt gtgcaaaaga aacaacgagt
    49921 cccatagcgg tagtgaagac acctaatgtg accattaccc ctaagaagct agcaccgaag
    49981 ttacctaaat aaaaattagt gatctgagaa agtgcagttc cgccattttc tgataaaggc
    50041 atcttattca aactcatcgc accgagaagg accagaccaa aataaatcat gacttctaac
    50101 gcaacgctca ggctaccagc ttttgctgtt aattctgtga cttttttatc tttaaaacca
    50161 agatcacgaa ctgcatggac aaaagtgaca cttaaagcaa gtaaagctac tgcatcaacc
    50221 gtgttgtatc cttctaaaac gccatttgtc aaagcgttcg tctgataaga atctgcagca
    50281 gattggttta gattccccat gggttggaat aaagaaacga caaaaatgat agctaataat
    50341 gcaagaaaca aggagtttaa atactttccg acatatttga ccaaacgtgt tggatgtaca
    50401 gtaaggaaat aagcaagtaa aaagaaaaga gcagagaata aaaacatacc taatgaatca
    50461 tatttttcag gcaaaaaggg tttagcagcc atttcaaaag cagttgctgc tgtccgcggt
    50521 gtaccaaaga atggtccgat cgttaaatga acaaggatca agaacaaggc agcataccat
    50581 tttccgacag gtttagctaa gtcatacaga ccatcacttt ttgtcactac tacagctaag
    50641 atagctaata atgggaaaag agcgcctgag atggcaaatc ctacaccagc gctgatccag
    50701 tttgatccag ccatttgacc taagtggaca ggaaagatca gattacctga cccgaagaac
    50761 atcccgaaga taagtgaact gaccatcaat aattgcttcc atgaataagt ttttgtttct
    50821 tccataaatt tttcctccaa taattatcat tttgagtaac aaaataaacg ttgcagaaac
    50881 tagaaatgcc actaatatca gattccatga aaaccaccac cttaaaatat aaaaaaaagc
    50941 ccttttccac ttgggaaaag ggctctagat tctagaacgg taccaccttt tttcgcttaa
    51001 aaaagcttct tcattcacgg acgcttttcg ataaagttat ccgctagcct gataatggag
    51061 gcagccacaa tgatctacgt tttcgacatt gactcggaaa tgatgttcgt ctattcgatt
    51121 tattgtcatt tctcacttac atgactcact gggaataaat cgctgaatag cctactgttt
    51181 tcctcgacgc tttgctgtat atttatttgt tgacgttata atacacctgt tttttttgaa
    51241 atgcaagaat atttcaaata ttttgttttc tttttttgaa acaagaaaaa tacccagaga
    51301 atacttgcta agttagacgg aatacttgtc ctctatctta tgcatagctt acatgatcag
    51361 ctttttttat tcaaacgaga cctttagaga atggaagcag ctatttttta acgtttcttg
    51421 gtacttatgg ttaagcaact cttttagaac cttttcttat ttgctatata gtttcttctg
    51481 agtatggtaa aataggaaag aatgaatcga aaaaaagggg atgtctattt ttgacggaag
    51541 agtctagttc tttagagatt agattgacgg ctgctgatga tgtcagcatg cttttaggtg
    51601 cacacgacaa gcatataaaa ctgattgaag aaacaacaga aacaaccatc catacacgtg
    51661 gagaaatcat tcagatcatt ggcgaacaat cccagatttc cttggctgcc tcagtcattc
    51721 ggacattgca ggaattgatc aaacgaggaa tccatgtaag tacaccagat gtcgtgacgg
    51781 cactgaaaat ggggcaaaaa ggcacattag attattttgt tgaaatgtat gaggaagaga
    51841 tcgtcaaaga ccgtaatgga aaaccaatac gggtaaaaaa cagcggccaa aagaaatatg
    51901 tcgaatcggt agccaaacat gatatcgtat ttggcgtagg accagccggg acaggaaaaa
    51961 cttttcttgc agtagtatta gcaatcgctg ccttgaaaaa aggtgaagtg caaaaaatca
    52021 ttttgacgcg gcctgctgtg gaagcagggg aaaatctagg ctttcttccc ggggatctaa
    52081 aagaaaaagt agatccttat ctgcgtcctg tttatgatgc tttataccaa atttttggat
    52141 tagatcatac gaaccgattg atggaacgag gcgtgatcga aattgctcct ttagcttaca
    52201 tgcgggggcg gacattggat gatgcattcg ttattttgga tgaagcacag aacacgacag
    52261 ttgctcagat gaaaatgttc ctgacacgtc ttggttatca atcaaaaatg attgtcaatg
    52321 gagatacgag tcagattgat ctgcctcgag ggacaacaag tggtcttgtt catgcagaac
    52381 gaacattaaa gcaaatcaag aaaatcgatt ttgttaattt tgaagcaagt gacgttgttc
    52441 ggcaccctgt agttgccgaa atcatcaaag cttatgaaaa ggcagatctc catcaagaat
    52501 aagctttgct taggaggata agcacatgtt gaataaaaca ctgcagaaac tacaagaaaa
    52561 acttggaaag gcagcattgc ctttcctgct gttcttgttt tttatcatta tctgcggcgt
    52621 tacatttagt agtgtcaaac aaaaggccaa tgatttcaga gaaggccaag tagcagaaga
    52681 aagtatccgt gcgaacaaaa cgatcgagaa cacggaagaa accgaacaaa aaagaaaact
    52741 ggcagcagaa gcagtcactc cagaatacac ttaccaaaaa gatcttgcag atgaccagaa
    52801 caatcggatc aagcaactat ttgaattgat cgataaaacg aatgatgcca tcaacaaatc
    52861 ttatgacgaa aagattgata aggcaaagga agatgaaaat atcccaaagc ctactacaga
    52921 agagcggatc gccgcgttga agaaaaattt tgaaaatgtg aatgcagaaa atgttgcgtt
    52981 ttatcaaaaa ctaccgaaca atttttattc gacgatattt gaaatgactg aaactgagat
    53041 ccatactgtg agggatgaga gtctgaagct cattgacgaa cagatgagca aacaagttcg
    53101 tgaaagtgaa ttggaagctt ttaaacaaga agcagaagag caaatccaat atttgaatgt
    53161 cacaccagca caacaacaaa tgattcgcta cttagtggat caaggtatcg tagtgaatga
    53221 cgtattgaat gagaaaaaga cagaagaatt gaaacaatcc gcacgagaag ctgtacaacc
    53281 agtgatgatc ttccaaggag aaatcattgt tcgtgaaggt aatcaaatcg atgcttcagc
    53341 tatgaaaaaa ttggaattac taggactgac taatcaaaca acttcgattt ttccgctaat
    53401 tgccatggtt ttagctgttt tgcttcaaat cggcgtactg atttataatt cacttcaatt
    53461 ccaaaatgca ggagaaagaa caaaatacgt gcttttctat gtgacagcta tgtcagtcag
    53521 catagtgctg atgaaatttt tccaattatt ccaaacggaa caagctactt atatcccgct
    53581 gttttatccc gctgcttttg caccacttgt tttaagcttt ttcttgaacc gaagagcagg
    53641 gatcatggct ggtattttcc aagcagtatc tgcacttttc attttttatg attcgattgg
    53701 cacgaacttt ctaacgatta tcttgatgtc ttatgttttc tctgggctca tggcaacgat
    53761 tgtcagacgc aaacggatct cagaacaagg attatctgct gccatgtggg tcattatttt
    53821 tcctgtgatg atggatgtca ttttgatcgt ctatcaagga atgagctttg gtgatgcaac
    53881 gacttggtta atgcttgtct gcgggttcac tggtgcactc ttctcattct tgctgacgat
    53941 cggtctacac ccatatattg aattgatggt caatgatgac agtgtaattg tattaaatga
    54001 actcagcaat ccaaatcatc ctttattgaa acagttgctg gaagaagcgc caggtactta
    54061 tcatcatagt atgatggtag ctaatctaag tgctaacgct gtagcagaaa tcggcggacg
    54121 ttctttgcta actcgagtag cttgctatta tcatgatatc ggcaagatca aacatgctag
    54181 ctttttcgtt gagaacttgc cttcaggagc ggaaaacccg cacaatttct tattgccaga
    54241 agacagtaaa catattatct ttggacatgt gacagatgga gccaaaatat tggaagatta
    54301 taatatgccg caaatggtga tcgatatttg caaacagcat catggaacca cgctaatgcg
    54361 ttatttctac atcaaagcga aagaacgcaa tccggaagta acagaagagc aattccgtta
    54421 tcctggacca aaaccgcaaa gtcgtgaagc agggatcgtc aatattgctg acagttgtga
    54481 ggctgcagta cgggcaatgg atcatccgac gagcgaaaaa atcgaaagtt ttgtccataa
    54541 tcttatcgaa gagcgtattt ccgatggtca attagacgat agtggactga ccttgaaaga
    54601 aatccgaaaa gtggaaaaat cattgatcag cggtttaagt agcaccttcc attctcggat
    54661 caaatatcct aaaatgaaaa cagaagttga gaagataaag gaagaacaag aagaatagaa
    54721 agaagcgatg tataatggat attaccttta tggatgaaac aaaccaagtc tcagaagaga
    54781 aaatgaaaga aatcgatgac ttgctgcaat ttgcagcatc ttatttaaag ctgccagagg
    54841 aaacagaaat gtctgttact ttcatggaca atgcggcaat ccaagtaatc aatcgtgatt
    54901 accgtggaaa agatgcaccg acagacgtca tcagttttgc tctggaagaa gaaggcgaag
    54961 acgaaatccc agtgattttt gaagatggag agaatccatt gcctcgtgta ctaggagaca
    55021 tcatgatttc tattgaacgt gctgctgaac aagcagaagc ttacggccat tcatatgatc
    55081 gggaacttgg ctttttagcg gtacatggat tcttgcatat caacgggtat gaccatatga
    55141 caccagaaga tgagaaagaa atgtttggtt tacagaaaga gatcttggat gcctatggac
    55201 tcaaaagata aaaacgtaga gaaaaacaaa catttcctga tgtctgtgga atttgctgtc
    55261 caaggagtca aaaccgtttt tgaggaagaa cgcaatatga ggaaacatgt tgcgttcggt
    55321 atccttgctt tatttatggg cgtgattttc cagcttgatc ggatagagtg gttatggctg
    55381 cttttagctg tttttctcgt ttggatagta gagatcatca atactgtttt tgaaaatgta
    55441 gtggacatgt ttacggattt tcattttcat ccgattggga aaaaaatcaa agatatggca
    55501 gctggagcag ttttagtgac cgcttgtttt gctgtcatca ttgggttgat tttatttgtc
    55561 cctaaaatat atcatttgtt gtttaattaa aaaggagaac gtatatgcca gaacataaat
    55621 cagggtttgt cgcaatcgtc ggccgcccga atgtaggaaa atccacatta ttgaaccgaa
    55681 tcgtgggtca aaaaattgcc attatgagtg acaaggcaca gacaactaga aataaaatcc
    55741 aaggagtata tactacacca gaagctcagc tgatttttat cgatacacca ggaatccata
    55801 aaccaaagca tcgtctagga gattttatgg tagaagcagc ttacagtgcg ttgaaagaag
    55861 tggatgcagt cttatttatg atcagtgctg atcaaaaacg cggccgggga gacgatttta
    55921 ttattgaacg tctaaaaaac gtgcattctc cagtttatct gattatcaat aaaatcgata
    55981 agatccatcc agacgagttg ctgggaatca tcgaagatta ttcgacgcag atgccttttg
    56041 cacaagtgat tccgatctct gctacagaag gaaacaatgt cgaacgctta atggatgtat
    56101 tagtcagtga aatgccagag ggcccacaat attttccaga tgatcaagtg actgatcatc
    56161 ctgaatactt tatcgtttct gaattgatcc gtgagaaagt cttgttttta acacgagacg
    56221 aagtgcctca ttctgtcgca gtcgttgttg attcgatgaa gcgaaacgag aatgataaaa
    56281 tccatatcca ggccacgatc atcgtcgaaa gagatagcca aaaaggaatc attatcggca
    56341 aaggcggaaa aatgctgaag caagtaggaa cgaaagcaag aaaggatatc gaaaatcttt
    56401 taggagacaa agtatttcta gaactttggg tcaaagtcca aaaagactgg cgagacaaaa
    56461 aagtctatct gcaagacttt ggctaccgaa aagacgaata ctgatattct gaacttctta
    56521 taggttaagt atagaaataa actggataaa aatccgcacg ttgagaaaaa cggcggaaga
    56581 tcgaaacata aataatctgg atcggcagaa tctgcttttc cagatttatt ttttaggagg
    56641 gagaatatga gccagcttgc agaatcgaaa ggcttgattt tatctagccg taattacaaa
    56701 gaaaaagata aattagtcaa aatctttacg gaatcttctg gcaaaatgat gttttatatc
    56761 aaaggaatcc atcggcaaaa tcagccatta gctccggctt tgctcccctt taccgaagca
    56821 gtctatatcg gtaattttcg aagtgaaggt ttgtcgtttt taagcagtgt caaagacgtc
    56881 catgcgtttc ggaacatcca agaagatatc tttttgagcg gttatggtac ctatttgcta
    56941 aatctagtag atgcagcaat cgaagatcat caatatgacc cgcatttatt ccaatttacg
    57001 caacaagctc tgcagcggat ggatcaagga gatgatgcag aaatcatcac gaatatcttt
    57061 gaagttcaaa tactgcaacg cttcggaatc gcgccaattt ggacgcactg tgtcgtatgc
    57121 ggggaaacaa aaggaaaatt tgactattct tccaaatctg gcggtgtgat atgcgagaaa
    57181 cactggccaa tggacgaaca ccgttatcat gcagatcctc gcgctgttta tttcgttcga
    57241 atgttttcgg ctatttctta tgataagatc agtggaatcc acttgaaaga agaaacgaag
    57301 caggcaatcc gtgacctcat tgaccagttg tatgatgaat atgtcggtat tcatctaaaa
    57361 agcaaaaagt tcattgatca aatgaagtct tgggcacacg tattaaagac gccagagaaa
    57421 aatatgcctg aaaaagagat acctgaaaaa gaagaataaa tgaaagatac aacaaaaaaa
    57481 tcaaaactat ttgacaaata cagggacttc cgtctattat taaccgtaga ttaaatagat
    57541 cgttcactga gaggatctat tatataaaca agaaaactgc aaaatgaata cgtacattga
    57601 ccaagatcag taaaaaacac gtggtttagc gagttcggga gagtggaagc cggacccaaa
    57661 cgatttttga agaggcactt gcgagtacga taaatgaagc tgccgaatct ttattcggaa
    57721 gtagggtgga accgcgaaat tattcgtccc tatgtctgta atcagacata gggacttttt
    57781 gtcgttttct ttcctgtatt cttattgaca gcaacgctta aaaattgaaa ggggcaaaac
    57841 agatgagtaa aaaattgacc gtccaagata tgattttaac attacaaaaa ttttggtcat
    57901 caaacggctg catgctgatg caagcttatg acacagaaaa aggagcaggt acgatgagcc
    57961 catatacatt cttacgggca atcggaccgg aaccatggaa tgctgcttat gtagagccat
    58021 cccgccgacc agctgacggg cgttatggag aaaacccaaa ccgtttgtat cagcatcatc
    58081 aatttcaagt cgtaatgaaa ccttcacctg aaaatatcca agagctttat ttagaaagct
    58141 tgcgtctttt aggaattgat ccattagaac acgatattcg ttttgttgaa gacaactggg
    58201 agaacccatc gatggggtgt gccggtgtgg gttgggaagt atggcttgat gggatggaga
    58261 tcacacaatt cacgtacttc cagcaagtcg gaggactacc ttgtaaacca gttacttctg
    58321 agatcactta tggactagaa cgtcttgctt catatattca agaagttgaa agtgtctatg
    58381 atctggaatg ggctgatggt gtgaaatatg gcgagatctt caaacaacca gaatatgaac
    58441 attccaaata ttcttttgaa gtaagtgacc aagacttgct actaagcaac tttgaccgtt
    58501 ttgaaaaaga agctaaacgc tgtatcgatg aaaatcttgt tcatccagcg tatgattata
    58561 ttttgaaatg cagccataca ttcaatttat tagatgctcg cggtgcagta tccgtaacag
    58621 aacgagcagg ttatctttcc cgtatccgca acatggctcg tgctgtagcc aaaatctttg
    58681 tggcagaacg cgaaaaatta ggattccctt tattgaataa aaacacagca aatccagaaa
    58741 acatgaagga ggctgaataa gatggcaaaa gacttattac ttgaaatcgg gctggaagaa
    58801 atgcctgctc atgttgtcac accaagcatg aaacaattag aagaaaaaac agcaaaattt
    58861 ttagatgaaa accaattgac ttatgatacg atcgaaacgt tttctacacc gcgccgctta
    58921 gcaatcaaag taacaaacat tccagaacgt caagcagaca gtgaagaaga agtcaaagga
    58981 ccagccaaaa aaattgcttt ggacgcagat ggaaactgga cgaaagcagc tgaaggattt
    59041 gtccgcggac aaggtctgac gacagatgct atcactttta gagaattaaa aggcgtggaa
    59101 tatgtctatg taacgaaata cactcacggc aaagaagcga aagaagtatt gacaggttta
    59161 gcagatgtca ttaaaagcct cactttccca gtaacgatgc attgggcaga atacgatttt
    59221 gaatatatcc gccctattca ctggatcgtg gcattgttag atgacgaagt aatcccgttt
    59281 gagatcttag atgtcaaaac aggcagagcc tctcgaggac atcgtttctt aggcgaagat
    59341 gtgacatttg cgcatgcaaa agaatatgaa gaaaaattga atgaacaatt cgttattgct
    59401 tcaccgcaaa aaagacaaga aatgatcgtt acacaagcaa atgaattagc cgaaaaaaat
    59461 cactgggtta ttgatctaga cgaagattta ctagaagaag tcaacaattt agtcgaatat
    59521 ccaactgtct tttctggcga cttcgaagaa aaatatcttt ctgttcctga agaagtacta
    59581 gtcacttcta tgaaagaaca tcaacgttat ttcgaggtac ggaacgatca aggtatgctg
    59641 cttcctcatt ttatttctgc tcgtaatggt gatcgggtaa aattggaaaa tgtggttcga
    59701 ggcaatcaaa aagtattgac ggctcgttta gaagatgcgg aattctttta taatgaagac
    59761 aagaaagctt caatcgacca atacgttgaa aaactaaaaa ctgttacttt ccatgaaaaa
    59821 atcggtagta tctatgagaa aatgcagcgg gtacaagtca ttgcccgtat cattggcgaa
    59881 caagtaggac tatctgagga agaattgatg gatctgcaac gagctgctga aatctataaa
    59941 tttgatctag taaccaacat ggtaggggaa tttcctgaac tacaagggat catgggcgaa
    60001 aaatatgctc tgctgaaagg cgagaaacct gctgtagcaa cagcgattcg tgagcattac
    60061 atgcctatat ccagtgaagg agagctacct cagtctacag taggttctgt tttagcgatt
    60121 gcagataaat tagatagcat tttttctttc tttgcagttg ggatgattcc aagcgggtca
    60181 aacgatcctt atgccttacg tcgccaagca tacggtgtcg ttcggatcat cgaatcgaaa
    60241 aaatgggcct ttcctttgtc tgttctgcaa gaaacgatta gtgatgttat cagtaaagat
    60301 acggatcgtt tcggcattgg tttatcagaa gggcaacaac aggtgatcga ctttatcaaa
    60361 ggccgtctgc gccaattatt gacaacgaag aatattcgtc atgatgtcat cgaagctgtt
    60421 ttgaatgcag aacaaaaaga tctgacaaaa gtatttgcag cagcacaatt gttcaagcag
    60481 catcttgcag atgaagactt caaaccatcg atggaagctt tgacacgtgt cgtgaactta
    60541 gcgaaaaaag cggagcttga aaaacaatca gaagtagacc ctgaactgtt cgaaaatgaa
    60601 gcggagaaag aactgcacaa agcagtagag gcaatgaaaa aaagctttgc tgaccaaacg
    60661 atcaacgaaa attatgatca gcttgtaagc cttcgcccac tgatcgaaaa ttattttgat
    60721 cagacgatgg tcatggcaga agaaccagca gtacgtaaga accgattaac gcaattaagt
    60781 caaattgctg ccatggcttt gtcgctagca agtttagatc aaatcatcac aaaataattt
    60841 ctaatatgta aataaaccag agaataggca caaaa
//
LOCUS       DARBDN010000007        60359 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000007 DARBDN010000000
VERSION     DARBDN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.007"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            73..591
                     /locus_tag="SCH06_000457"
     CDS             73..591
                     /locus_tag="SCH06_000457"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEG1077061.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            719..1402
                     /locus_tag="SCH06_000458"
     CDS             719..1402
                     /locus_tag="SCH06_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEG1077062.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1711..1784
                     /locus_tag="SCH06_000459"
     tRNA            1711..1784
                     /locus_tag="SCH06_000459"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1745..1747,aa:Arg,seq:tct)
     gene            1943..2302
                     /locus_tag="SCH06_000460"
     CDS             1943..2302
                     /locus_tag="SCH06_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HEG1077063.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2425..4056
                     /locus_tag="SCH06_000461"
     CDS             2425..4056
                     /locus_tag="SCH06_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HEG1077064.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4118..4759)
                     /locus_tag="SCH06_000462"
     CDS             complement(4118..4759)
                     /locus_tag="SCH06_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEG1077065.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4945..5021
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5041..5349
                     /gene="rplU"
                     /locus_tag="SCH06_000463"
     CDS             5041..5349
                     /gene="rplU"
                     /locus_tag="SCH06_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEG1077066.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5376..5720
                     /locus_tag="SCH06_000464"
     CDS             5376..5720
                     /locus_tag="SCH06_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEG1077067.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5733..6026
                     /gene="rpmA"
                     /locus_tag="SCH06_000465"
     CDS             5733..6026
                     /gene="rpmA"
                     /locus_tag="SCH06_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEG1077068.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6460..9267
                     /locus_tag="SCH06_000466"
     CDS             6460..9267
                     /locus_tag="SCH06_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1077069.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9458..9949
                     /locus_tag="SCH06_000467"
     CDS             9458..9949
                     /locus_tag="SCH06_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1077070.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10052..11041
                     /gene="manX"
                     /locus_tag="SCH06_000468"
     CDS             10052..11041
                     /gene="manX"
                     /locus_tag="SCH06_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEG1077071.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11074..11877
                     /locus_tag="SCH06_000469"
     CDS             11074..11877
                     /locus_tag="SCH06_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEG1077072.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11898..12812
                     /locus_tag="SCH06_000470"
     CDS             11898..12812
                     /locus_tag="SCH06_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEG1077073.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12895..13269
                     /locus_tag="SCH06_000471"
     CDS             12895..13269
                     /locus_tag="SCH06_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEG1077074.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13408..13653
                     /locus_tag="SCH06_000472"
     CDS             13408..13653
                     /locus_tag="SCH06_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEG1077075.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13825..14889
                     /locus_tag="SCH06_000473"
     CDS             13825..14889
                     /locus_tag="SCH06_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEG1077076.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15135..15560
                     /locus_tag="SCH06_000474"
     CDS             15135..15560
                     /locus_tag="SCH06_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEG1077077.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15553..16002
                     /gene="nusB"
                     /locus_tag="SCH06_000475"
     CDS             15553..16002
                     /gene="nusB"
                     /locus_tag="SCH06_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEG1077078.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16099..16953
                     /locus_tag="SCH06_000476"
     CDS             16099..16953
                     /locus_tag="SCH06_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEG1077079.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16954..18291
                     /locus_tag="SCH06_000477"
     CDS             16954..18291
                     /locus_tag="SCH06_000477"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEG1077080.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18296..18520
                     /locus_tag="SCH06_000478"
     CDS             18296..18520
                     /locus_tag="SCH06_000478"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEG1077081.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18522..19412
                     /locus_tag="SCH06_000479"
     CDS             18522..19412
                     /locus_tag="SCH06_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEG1077082.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19421..20239
                     /locus_tag="SCH06_000480"
     CDS             19421..20239
                     /locus_tag="SCH06_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEG1077083.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20346..20795
                     /locus_tag="SCH06_000481"
     CDS             20346..20795
                     /locus_tag="SCH06_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEG1077084.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20813..22495
                     /gene="recN"
                     /locus_tag="SCH06_000482"
     CDS             20813..22495
                     /gene="recN"
                     /locus_tag="SCH06_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEG1077085.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22550..22666)
                     /locus_tag="SCH06_000483"
     CDS             complement(22550..22666)
                     /locus_tag="SCH06_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEG1077086.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22739..23695)
                     /locus_tag="SCH06_000484"
     CDS             complement(22739..23695)
                     /locus_tag="SCH06_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEG1077087.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23866..24234
                     /locus_tag="SCH06_000485"
     CDS             23866..24234
                     /locus_tag="SCH06_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEG1077088.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24404..24835
                     /gene="mraZ"
                     /locus_tag="SCH06_000486"
     CDS             24404..24835
                     /gene="mraZ"
                     /locus_tag="SCH06_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HEG1077089.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24856..25815
                     /gene="rsmH"
                     /locus_tag="SCH06_000487"
     CDS             24856..25815
                     /gene="rsmH"
                     /locus_tag="SCH06_000487"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEG1077090.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25820..26221
                     /gene="ftsL"
                     /locus_tag="SCH06_000488"
     CDS             25820..26221
                     /gene="ftsL"
                     /locus_tag="SCH06_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEG1077091.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26222..28414
                     /locus_tag="SCH06_000489"
     CDS             26222..28414
                     /locus_tag="SCH06_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEG1077092.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28440..29402
                     /locus_tag="SCH06_000490"
     CDS             28440..29402
                     /locus_tag="SCH06_000490"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEG1077093.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29416..30777
                     /locus_tag="SCH06_000491"
     CDS             29416..30777
                     /locus_tag="SCH06_000491"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEG1077094.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30803..31891
                     /gene="murG"
                     /locus_tag="SCH06_000492"
     CDS             30803..31891
                     /gene="murG"
                     /locus_tag="SCH06_000492"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HEG1077095.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31906..33126
                     /locus_tag="SCH06_000493"
     CDS             31906..33126
                     /locus_tag="SCH06_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEG1077096.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33282..34607
                     /gene="ftsA"
                     /locus_tag="SCH06_000494"
     CDS             33282..34607
                     /gene="ftsA"
                     /locus_tag="SCH06_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEG1077097.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34630..35871
                     /gene="ftsZ"
                     /locus_tag="SCH06_000495"
     CDS             34630..35871
                     /gene="ftsZ"
                     /locus_tag="SCH06_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEG1077098.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35888..36565
                     /locus_tag="SCH06_000496"
     CDS             35888..36565
                     /locus_tag="SCH06_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEG1077099.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36579..37178
                     /locus_tag="SCH06_000497"
     CDS             36579..37178
                     /locus_tag="SCH06_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEG1077100.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37193..37480
                     /locus_tag="SCH06_000498"
     CDS             37193..37480
                     /locus_tag="SCH06_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEG1077101.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37529..38311
                     /locus_tag="SCH06_000499"
     CDS             37529..38311
                     /locus_tag="SCH06_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEG1077102.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38332..39039
                     /locus_tag="SCH06_000500"
     CDS             38332..39039
                     /locus_tag="SCH06_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEG1077103.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39301..42099
                     /gene="ileS"
                     /locus_tag="SCH06_000501"
     CDS             39301..42099
                     /gene="ileS"
                     /locus_tag="SCH06_000501"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEG1077104.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42148..43674)
                     /locus_tag="SCH06_000502"
     CDS             complement(42148..43674)
                     /locus_tag="SCH06_000502"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEG1077105.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43689..44336)
                     /locus_tag="SCH06_000503"
     CDS             complement(43689..44336)
                     /locus_tag="SCH06_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEG1077106.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44520..44849)
                     /locus_tag="SCH06_000504"
     CDS             complement(44520..44849)
                     /locus_tag="SCH06_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HEG1077107.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45026..45754
                     /gene="sfsA"
                     /locus_tag="SCH06_000505"
     CDS             45026..45754
                     /gene="sfsA"
                     /locus_tag="SCH06_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HEG1077108.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45770..46783
                     /locus_tag="SCH06_000506"
     CDS             45770..46783
                     /locus_tag="SCH06_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1077109.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46783..48060
                     /locus_tag="SCH06_000507"
     CDS             46783..48060
                     /locus_tag="SCH06_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEG1077110.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48123..50825
                     /locus_tag="SCH06_000508"
     CDS             48123..50825
                     /locus_tag="SCH06_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1077111.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50977..51294
                     /locus_tag="SCH06_000509"
     CDS             50977..51294
                     /locus_tag="SCH06_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1077112.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51324..51644
                     /locus_tag="SCH06_000510"
     CDS             51324..51644
                     /locus_tag="SCH06_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEG1077113.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51752..53212
                     /locus_tag="SCH06_000511"
     CDS             51752..53212
                     /locus_tag="SCH06_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1077114.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53280..53501
                     /locus_tag="SCH06_000512"
     CDS             53280..53501
                     /locus_tag="SCH06_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077115.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53532..53714
                     /locus_tag="SCH06_000513"
     CDS             53532..53714
                     /locus_tag="SCH06_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HEG1077116.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53714..54127
                     /locus_tag="SCH06_000514"
     CDS             53714..54127
                     /locus_tag="SCH06_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEG1077117.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54250..55431
                     /locus_tag="SCH06_000515"
     CDS             54250..55431
                     /locus_tag="SCH06_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1077118.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55502..55666)
                     /locus_tag="SCH06_000516"
     CDS             complement(55502..55666)
                     /locus_tag="SCH06_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077119.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55820..55893
                     /locus_tag="SCH06_000517"
     tRNA            55820..55893
                     /locus_tag="SCH06_000517"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55854..55856,aa:Arg,seq:cct)
     gene            complement(55962..57101)
                     /locus_tag="SCH06_000518"
     CDS             complement(55962..57101)
                     /locus_tag="SCH06_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1077120.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEVK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINAVFDSLYKNDN"
     gene            complement(57211..57861)
                     /locus_tag="SCH06_000519"
     CDS             complement(57211..57861)
                     /locus_tag="SCH06_000519"
                     /inference="COORDINATES: protein motif:HMM:NF023043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HEG1077121.1"
                     /translation="MKKNLILGFICTSILTLGACSSPSNNATNSETQKTINSLKKENE
                     ELKKQIASQSNDTEENSESIDNASKEKTLPVVGILEYTISSIKTEQVTNDEDNFTNAE
                     YNFSGIENFPEKYYRTTISYKLKNKATSPFSLSSYQASLIDGDGMEYSRTAGEYFLYD
                     ENSNSLVQPETTTSGVFYLLSKNKPNLSTFKLNASKQFTDDFTAEPIGEAGTTEYK"
     gene            complement(57998..58651)
                     /locus_tag="SCH06_000520"
     CDS             complement(57998..58651)
                     /locus_tag="SCH06_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077122.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETNISKTKET
                     TEISSSTSKSTSKTDSSSTVTSSNQATAKPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNTEAQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(58701..59129)
                     /locus_tag="SCH06_000521"
     CDS             complement(58701..59129)
                     /locus_tag="SCH06_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEG1077123.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRDRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIEELKNLYGLPESAYRFLI"
     gene            complement(59134..59508)
                     /locus_tag="SCH06_000522"
     CDS             complement(59134..59508)
                     /locus_tag="SCH06_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077124.1"
                     /translation="MSLVTKIKELADEKHVTIAEVERQVGISNGQIRRWDKASPKSEN
                     LKKVADYFGVTTDYLLGNNNVPKWATKEEVVELDKLLDSNVNMSYGGETLTPEQIQRV
                     KDILIATFWDIVKEDKEKGKKM"
     gene            59811..59996
                     /locus_tag="SCH06_000523"
     CDS             59811..59996
                     /locus_tag="SCH06_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077125.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQEHIETVKKILGIQ"
     gene            60009..60347
                     /locus_tag="SCH06_000524"
     CDS             60009..60347
                     /locus_tag="SCH06_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HEG1077126.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT        19794 a        10178 c        12801 g        17586 t
ORIGIN      
        1 gctataattt gaaaaaaatt tatcgttatt atatgattaa gaaggattga ataaagaaag
       61 aagttgaaaa cgatacctga ttacaaaaaa ataactttta taagttctat aacgttgatt
      121 atatttttaa ttcttattct tctcgtcgtc ttggttcccc gaatttttgg tttgactcct
      181 tatattattg aggacaaaga aatgagtcca tattatgcac aaggaaatct gatatatgta
      241 cgaccgaaaa atacaaatga gattttagtc ggagatatta ttacatatta tgaaaattca
      301 ggaaaaaaaa tctcgacgcg tcgcgtaata gccgttgaaa acaaccacga agatttttat
      361 acaaaagctg atacaaagac ttatattgag cctggagtag taaaaaagag aaatattatc
      421 ggtagtccca tctttcagat tccatatatt ggactagtcc tttcaaaaac ggcatttgca
      481 tggattcagg ggttattctt tacgattgct ttttgcctaa caggaatcac agcatggaat
      541 acctttgtag agttgaaaaa gaagcggaga cgaacacaga aatttttgta agaatgttaa
      601 aaacataaat gtattccaga gatccaacga ctcttctgaa catgaaacac gagaaaacac
      661 tcatgcagct tgtagattta gtcagttgtt cgtataatgt gtgaagagga ggagtagtat
      721 gcgcaatgaa atgatgcatc gtcctgtagt caaagaagaa ctattggatt ttatgcgtac
      781 ccagcaaaaa aaattaccgg gtgagctagg caaactggaa gaagaagctc atgtagcaga
      841 agtaccagtt attccccatg aaacagttgt atttttgaaa tttttacttg gacagcttca
      901 gcctgaacga atcttggaga tcggagcagc tatcggtttt tcatcaagtg tcatggccac
      961 gacaatcgga gaaaacgctc atgttacgac aattgatcgt ttcgatgtca tgatcgagaa
     1021 agctaaaaaa aactatgaac gtctaggact gacagataaa gtgactttgc ttgaaggtca
     1081 agcagcagat atcttgccgg agttgtctgg tccgtatgac tttattttta tggatagtgc
     1141 aaaatcaaaa tatattgaat ttttacctga atgcttacgt ttgttaagaa aaggtggcgt
     1201 tttgatggta gatgacatct tccaaggagg aacgatcttg ctcccagatg aagagattcc
     1261 ccgtggcaaa cgagctatcc atcgtaaatt aaatgaattt cttcgtgttg tgatggatca
     1321 tcccgatttg acatcgacaa tcttgccatt aggtgatggt gtgatcttaa tgacaaagga
     1381 atcagaaaca atcgagttgt gatacatgat tatggcagcc tgtagataat cgattgaatc
     1441 gagggctcaa ttcgaacttg atgtaaaagt ttctatattt gtaagtcaat taaaggatac
     1501 aggaaatcta aataaacagg agtagcatga agtcaatgta gctcctgttt tcaattgata
     1561 accttagaac agctgaagga gaatgtctcg ttttaaaaga ttgatttagt agttgggcca
     1621 aaataattca ttatttgcta attaaataac tatttcgtat tgacagaagc aatttaatta
     1681 tctataatta ttgatgttcc gctgattctt gtcatagtag ctcagctgga tagagcatcc
     1741 gccttctaag cggacggtcg ggggttcgaa tccctcctgt gacgctaaaa aaccgttaga
     1801 aactgaggtt tctaacggtt tttctttgtt ttttgtgcca atattgtttg ttttcaaagg
     1861 caaataaaat aaaaaaacat ccttatcgag tacaattata aggagcaaaa aaataaaact
     1921 catcagaaaa gaggaagaag atatgacgat actatctaga attttagtga ctctagttgc
     1981 aattgaattt ttttatatca tgtatatcga aacggtgaga actgattctg acacgacaag
     2041 tagggttttt aaaatgagta aagaagagtt aagcagaaaa tctgttcaaa cattgtttaa
     2101 gaaccaagga gtgtacaatg gactattagg agtgggacta ctttatggag cttatctttc
     2161 ttccgcatct aaagaaatca caagtatgct attaatatct attttttttg ttgcattata
     2221 tggcagtttg actagcgatc gttggatttt actcaaacaa ggtgggctag ctctgttggc
     2281 attgctttct attttcttat aaatatagaa aaaataagaa tttatctaac aggaaacttt
     2341 gtgaaaaata ttactttatc tcatgaaata tgatattcta atgaatggta ttttagaaaa
     2401 tttcatgaaa aaggagttag ataggtgttc aaaaattatg tttcctcact aaaaaaagaa
     2461 ttttcaggtt atgatctttc aagatttcag aaagatcttt tggctgggat cacagtagct
     2521 gctgtagcat tgcctttagc cttggctttt ggggtatcaa gcggagctga tgcggccgca
     2581 ggtttgatta cggctatcat tgccggtatc gttattggcg gtttatcagg cggtttttat
     2641 caaatatcag gtccgacagg tgcgatggca gctatcttga tgtctattgc ggcaacaaag
     2701 ggaatgcaag gtgtattgct tgctactttt ttagcgggtc tatttttact tgcagcagga
     2761 cttttccgat taggaacact gacttctttt atcccagcac ccgtaattac ggggtttact
     2821 tcaggtattg ctatcattat tgcattaggt cagatcgata atttatttgg tgttcactcg
     2881 gaaggtacaa acgttattga aaaactaagt agttatcaaa cgataggatt tccgataaac
     2941 acagcctctt tgatcatggg agggctagtc attttaggga tgtttatcta tccaaaaaaa
     3001 tgggcgaaac gaatgcctag ttcgctgctg gctatcattt tggcaacagc agttatgcta
     3061 ttgttccatt taccagtagc aactgtgggt aagattccac aaacattgat cagtagtaat
     3121 cgtttgaata tgggagattt tagcttttct gccttgcaac aagtggcagt tccagctatt
     3181 agcattgctt tattaggaat gattgaaagc ttgctatgtg gtgcttcggc tggccgaatg
     3241 gcaaataagc ccttagatag caatcaagaa ttaatggcgc aaggaattgg aaatctgttg
     3301 cttcctttct ttggcgggat tcctgctact gcggccatcg cccgtacaag cgtggccatc
     3361 aaatctggtg cacaaactag attagctggt atgatacatg cagttgtctt actgctctcc
     3421 atgcttgttt ttgcgccagt gatgtcacag attccaatgc cagcacttgc aggtgttttg
     3481 attgtgacgg cttggcgtat gaatgaatgg gaaacgatca aggagctatt tactaataaa
     3541 tattggtcag cagttctatt gtttatcctt acgatgattt gtacagttat ctttgattta
     3601 agtattgcta tcgtgatcgg ggtgatcggc ggctgtgtat tttttgttgt caaaagcgct
     3661 gctatcacga tttcattaga aacgatcgat tggcaaagaa tggggctgcc agaaacggaa
     3721 aagctgaata actggacagt agtgtatatt agtggtccac tgttttttat gtcttcagaa
     3781 aaactcaaaa ataaattgga agaactaaat catcacgatg gtgtcatttt ctccatgcga
     3841 ggcgtaccaa gtattgattt gacggcacgt gcagtttttg atgaatttca agaaaaagca
     3901 gagcaaagag gacaaacgat tatctatact tccttgcagc cagaagtaga aaaacaactt
     3961 tctcacttgt gggaacatac attcacgcat caacatcaaa cagttgctca tgcgttgaca
     4021 gctttacatg cgaaatatac tgcaattagc cattaaaaca atgaaaaaga acagacaaga
     4081 ctgtaaactg aagattttat ggtcttgtct gttcttttta atattgctgt aaaagtgaag
     4141 ctagtacttg ccagtcttga tggataacag gtacaaggga gcgattgtag aaaatagctg
     4201 ctggatgaaa aagtggaaga attcgatagt ttttttctga ccattcgtag gcatcctttt
     4261 gttctgttaa ttgtaagaca ggccctgtat agagttgacc atgatttttg gtaaccgtat
     4321 attctttgcc aagtaaacgt tgaagaccaa tgtttccaag tgtcgcaatt aattttggct
     4381 ggaccttcat cagttcgtaa tccaatattg gtgcatgcgc aaatacttcg gaacgagtag
     4441 gtgtccgatt tggataaaca gtttctgact gttgtgtccg tttattgatc cgatgagtca
     4501 cgcgatacgg gcggctcctt acagcactgg tgatatacac ctcttctcgt gttaagccag
     4561 ttgaagaaag tgcctgcatc aattcttttc cagcttgacc gctaaaagga acatgcgtat
     4621 caatctctgt tttccctggg gcttctccca cgagcatcag tttaggatga agaggtcctt
     4681 gcccagcgat aaatccttct acaggacggc cgttcattct taaagaagct tcttgtatca
     4741 gttcttttgg gtattccatt tatgctcctc ctttttcttt tattataaga ataaaagaaa
     4801 cacaatgcga ctattttatt tggtagaact gtgaggatag aaaagcagaa gtattgcttg
     4861 aatttttgtt ttactttttg attttaaatt tagttgacta acggttgctg ttctggtaag
     4921 ctagtactgt tgtaattgtg gactccacag ctacaaccgc tcagaacaag taataagcac
     4981 agcatatgct gtcacttcgg atggcgagtc taagtatatc agaaggaggt gctttatagc
     5041 atgtacgcaa ttattaaaac tggtggtaaa caagtaaaag ttgaagtggg acaagcaatc
     5101 tatgttgaaa aacttgacgt tgaagcagga gaaaaagttg tttttgacga agttatctta
     5161 gtaggcggag aatctacaaa agtaggcgct ccaactgttg caggtgcaac tgttgaaggt
     5221 actgttgaaa aacacggcaa acaaaagaaa gtcgttactt tcaaatacaa acctaaaaaa
     5281 cattcacacc gtaaacaagg tcatcgtcaa ccatatacaa aagtggttat cgacgcgatc
     5341 aacgcttaat agcgtttgag aaagaaggcc tatatatgat caaaggaaca tttaagcgaa
     5401 atgacgcagg tcagatcgtt tcattcactt tgaccgggca tgctgatgct ggtccttatg
     5461 gaagtgatat cgtttgtgcg ggtgtttctg cgttagcgat cagcactgtc aacgggattg
     5521 cctcattagc cggttttgag ccgattgttg aaatgaatga agaagaaggc ggttatcttt
     5581 ataccgaagt cacttcagga atgacacaag aacaaaacaa tattgctgag attctattag
     5641 aaaatctttt attaggatta caatcgatag aagctgaaaa ctcagaatat atccaaatta
     5701 aaacaattaa tgataaatag gaggtgcaga ccatgttgtt atctatgaat ctacaattat
     5761 ttgcccacaa aaaaggtggc ggttctacat ctaacggccg tgactcagaa tcaaaacgtc
     5821 taggtgctaa acgtgctgat ggacaaacag ttacaggtgg atcaattctt taccgtcaac
     5881 gcggtacaaa aatctatcca ggtgtaaacg tgggtatcgg tggagacgac actttatttg
     5941 caaaagttga tggcgtagta cgtttcgaac gtaaaggccg taacaaaaaa caagtgtctg
     6001 tttatccagt agctcaagaa gcttaattga atcttatgat taaagaggtt gtgacaagac
     6061 ttttgtcaca gccttttttg tttataaaaa taaaagttgt agtggaggct acgaagttta
     6121 ctttgtcttt ttacacttaa tatttttttg ccaatttgga atcaggatgt tttgataact
     6181 atcgttttca attgatggaa gctatattgt ttgctatcag tgaaataatt atatggtaaa
     6241 cagtgttctt tttcttgttt ccattataaa aatcgtatcg ggatttttcg ttcttttaaa
     6301 ttgaacattt ctatctatcc gcgtgttatc aacaaaacaa aatcaggtaa atagttgacg
     6361 aaacagaaat aaatacatag tattatgttt tgaagcctaa gtacaatagt ctatagaaaa
     6421 ggagcgatac cattggcaaa acgcattgac cgaatttata tgtatgtcaa agaaaaaacc
     6481 gctcatttaa caaaggcaga atatgatcaa ggagtaacaa cacaggaaat tgctgaagtg
     6541 ttagggattc agcgaacaaa tagcagtaaa gatctgaatc agctagtgcg cgaaggaaaa
     6601 ctgataaaga cagacggacg accagtacgt tacatatatc aaacactcgt tacgcacgta
     6661 aagccagtta caaaacatgt agtcagttac aaagaaacgc cggtctctga agaaaaaaat
     6721 acactccaaa tagatactaa ggatatcttt gcaaaaatca ttggagctaa cggcagcatg
     6781 aaaaattcag tggaacaggc aaaagctgcg attttgtatc cgccaagagg attaaattgt
     6841 ttgattacag gacctaccgg atcaggaaag acttattttg cacacgcgat gtatcatttt
     6901 gcaaaagcgc atcatgtaat agatgaggaa acggaactga ttgttttcaa ttgtgctgat
     6961 tatgccaata accctgagct tttgatgagt catttatttg ggtacgcaaa aggtgctttt
     7021 acaggcgcag atgaagaaaa aatggggatt atcgatcaag cggatggcgg tatgctgttt
     7081 ttggatgaga ttcaccggtt gccgcctgaa ggtcaagaaa tgatctttta ctttatggat
     7141 catggaactt acagtcgtct tggggaaaca acgaaatccc atgaagcaaa tgtacggatc
     7201 gtaggtgcga ccacagaaga cccaggttct tctctattag aaacttttgt tcggcgtatc
     7261 ccaatcaata tcaaacttcc ggcttttgaa aaacgtcctg caaatgagaa agtcgattta
     7321 gtaaaaatca tgattgccca cgaagcaaac cgcacgcagc gaaagatttc tttgacagaa
     7381 gatgtagcaa aagcattgat cggcagtgtg acctatggaa atataggaca attgaagtca
     7441 aatatccagt tagtatgtgc acgaggattt ctaaatcata tgcaatcacc cgaaatctcg
     7501 atcacaatcg atgatttgac agaagggatt cgtagcggat tgattcaatt agcaagcaac
     7561 cgcagtgcaa tggcagagct ttctaaaata ttggagccaa agataactgt agcaccaaat
     7621 gatacgatca tgaaaatcca atcggactcc tatgagttac cttataatct atatgatatc
     7681 atcggagata aagcagcttt actgaagtcg gatggtttgg atcaagaagc aatcaatcat
     7741 ttcatttcta cagatatcaa catccatctg aagtctttct ataaagacca tggtttttct
     7801 tttaatgcag acagcaaatt agcagaattt gtagatccga aaatcataga agtgaccaat
     7861 cagatttatg taatggtcaa aagatcttta ccatatgagt ttcagcaaaa ctttatttat
     7921 gctatgagct tgcatatcag ttcttttttg aaaaaaatca acttaggaga agaacggcat
     7981 acgaatgata acatccgtga gatggctttt gattttccag atgaatatgc tgttgcgaaa
     8041 gaagtgcgta gttatatcga aacgtatttt caagtggaga ttccagaaag tgaagactat
     8101 tacttgaccg ttctactcgt ctcgttacgg gcaaatcaag caagcggcag aatcggtgta
     8161 gtcgttgcag ctcacggaaa cagcacagca agcagtatgg tccaagttgt ccaacagttg
     8221 ttagatgcag agaacgtacg agcagtagac atgcctttgg atatggatcc gaaaacagca
     8281 ttggaccgaa ttgaacgcaa tgtacaagaa gtagatgaag gaagcggggt catactctta
     8341 gtagatatgg ggtcccttgc gtcgtttaat tcgcaaattc aaagagacac tggaattcca
     8401 gtacgtactg ttgatatggt aacaacttct ctagttttgg aaactgtacg aaaggtctca
     8461 gtattaggga cagatctaga tatgttgcat gaatcattga aaaattttcg aggttacgca
     8521 gaaatatctt ctgtagaatc tgttcaggaa gcaaaaccta ttcataagaa aaaagctgtt
     8581 ttggctatct gcgcatctgg cgaaggtaca gcacaaagaa tcaaagaatt gatcgaacga
     8641 gcggtaaaca agcgtcaaga aacagaatta gaagttctag ctttgtcgat tgtggaagtg
     8701 aaagaagaac tgccagttat ccaaaaagaa tatcagatca tagctactac tgggattact
     8761 gatttgaata tccaagcccc atttattcct ttagaacgtt ttattgatca aaatatcgaa
     8821 gtcattttgg atcagttgct gatggaatca gaattggagg aaactgaatt catctcccta
     8881 gatgaagagt cagctaaaaa tacgtgtgtt gagtttatct ctgataactt catctttatt
     8941 aatggtagta agttaatcga tccaatgtgg caattttcta cacaaatctc tcagacgacg
     9001 ggaatcggcg atgaagaata tggattcaaa atcaacctag tgatgcacac agcaggaatg
     9061 atcgaacgta ttattcggaa tgaaccattg actgtggaag aaaacgaatt gacaaataca
     9121 acgaatgatc ctctttatag ccaattggca gcctcagttg ttctgttgga agatcagata
     9181 aaagtaaaag tgccgataga agaaatgtat tatctgctac gtctagtcca taatcagtta
     9241 gataaaaaag aatacactgt gccatgaata cacaaaaacg atacactttt atagtgtatc
     9301 gtttttgtgt attggttaag aatcctttaa attcaattag tgtatcgtaa aaaagttggc
     9361 acgctttttg cttatagtag tgtgtgctag gaggtggttg ttcacacaga aatgataggg
     9421 gtttctgtga agtagtgagg aagaaggagt tttgcagatg gatattcgat tggcacgtat
     9481 agatgatcgt ttaatccacg ggcaagtcgc aacagtttgg tcgaagcaaa caggtgttga
     9541 acgtatcatt gtgatcagcg atgtagtcgc tcaagataaa ttgagaaagt ttctactaaa
     9601 agaagctgca ccgccgggga tcacagcaaa tgtaataacc gtgcagaaaa tgattcaaat
     9661 ctatcatagt ggattattat cacgagcaaa agtgatgctt ttattcacca atccccaaga
     9721 tgttgaagcg gttgtccgct gcggtgtaca gttgaagtcg ttgaatatcg gcggtatgag
     9781 ttttactgaa ggcaaatcaa tgattaccaa ttttgtttca gtaaatcaac aagatattga
     9841 ttcctttcgt tacttgaaca gtcaagaagt ggagttagag attcgaaaag tacctgctga
     9901 caggaaaatc cttttgatgg aactactagc gaaaatcaaa aaggtgtagc aagaatggtt
     9961 gttggaaaag gtcaaataat tctgttgtaa tggttagcaa ttattaatat ttttgaattt
    10021 gttacaacaa aagtaaatag gaggtataaa tatggtaggg attatcctag caagtcatgg
    10081 acaatttgct gaaggaatct tacaatccgg ttcaatgatc tttggcgaac aagaaaacgt
    10141 caaagccgtg attttgaaac caagtgaagg tccagatgac ttgagagcca aattggaaga
    10201 agcggttgct tcttttgata atcaagacga agtgttattc ttagttgatt tatggggcgg
    10261 aacaccgttc aatcaatcaa acacattatt cgaagagcac aaagataaat gggcaatcgt
    10321 cagcggtttg aatttaccaa tgttgattga agcctacgca tcacgctttt caatggaatc
    10381 tgctcatgaa attgcagcac acatcattga aacagcaaaa gacggtgtaa aagtaaaacc
    10441 ggaagaatta gaaccggcag aagcaccgaa agcagcagtt gaagacgcac aacctaaagg
    10501 agcacttcca gaaggaactg tggtcggaga cggaaaaatc aaatatgtat tagcacgtgt
    10561 tgactcacgt ctgttacatg gacaagttgc gacagcttgg acaaaagcag tgcaaccaaa
    10621 ccgtattatc gttgtttcag atgcagtatc aaaggatgat ctgcgtaaga gactaatcga
    10681 acaagctgct cctccaggtg taaaagcaaa tgttattcct attagcaaaa tgatcgaagt
    10741 agcaaaagac cctcgttttg gaaataccaa agcattgctt ttatttgaaa atcctgaaga
    10801 cgtattgaca gctgttgaag gtggcgtaga catcaaagaa ttaaatgttg ggtcaatggc
    10861 gcattcggtc ggtaaagtcg ttgtaagtaa agtattgtct atgggacaag aagacgttga
    10921 agcgtttgag aagcttgaac aaaaaggtgt gaaattcgat gtacgtaaag tacctaatga
    10981 ttcacgcgat aacatggatg atattttgaa aaaagcaaaa gctgaattag caaaagcgta
    11041 ataaataata ttaaaattta taggaggctt atcatgtcta ttatttcaat aattttagtc
    11101 gtattagttg cctttctagc tggtatggaa ggtattcttg atgaatttca atttcatcaa
    11161 ccactagtgg catgtacatt gatcggttta gttaccggta acctcgaagc tggtatcgta
    11221 cttggcggta cgcttcagat gatcgcttta ggttgggcaa atatcggtgc cgctgtagca
    11281 ccagatgctg cattagcatc agtagcatca gcaattattt tagttttagg tggacaaggt
    11341 gttaaaggtg ttccttctgc gatcgcgatt gccgttcctt tggctgttgc agggttgttc
    11401 ttaacaatga tcgtacgtac aatcgctgtt ccaatcgttc atttgatgga tgcggctgct
    11461 gaagaaggaa acatccgtaa ggttgaaatg tggcacatca ttgctgtatg tttacaaggg
    11521 gttcgtatcg cggtcccagc agcagcgttg ctatttatcc cagcacaaac tgtgcaatca
    11581 ttccttgaat caatgccagc atggttaaca gatggtatgg ctatcggtgg gggaatggtc
    11641 gtagctgtag gttacgcttt ggtaatcaac atgatggcta caaaagaagt atggccattc
    11701 ttcgttattg gtttcgttgt agctgcaatt tctcaattaa cattgattgc tctaggtgct
    11761 ttaggtgttg cattagctct tatttacttg aacctttcta aaatgggtgg ttcatcaaat
    11821 aatggaggcg gaagcaactc tggtgaccct ttaggcgaca ttttgaatga ctattaatct
    11881 tgaaggagga aaataaaatg gcagaagaaa aaatcaaatt atcaaaaaaa gatcgtttag
    11941 ctgttgcgtg gcgctctacc ttcattcaag gttcatggaa ctacgaacgt atgcaaaacg
    12001 gtggctgggc attttctatg attccagcaa tcaaaaaatt atacaaaaca aaagaagaac
    12061 gttctgcagc attaaaacgt cacttggaat tctttaatac acacccatac attgcttctc
    12121 caattttagg ggttacattg gctctggaag aagaacgtgc gaatggcgcg cctgttgatg
    12181 atgtagcgat tcaaggggtt aaagtaggta tgatgggtcc tttagctggt gttggtgacc
    12241 cagtgttctg gtttacagta cgtccaatgc taggtgcact aggtgcttca ttagctatgg
    12301 gaggaaatat ccttggacca atcatcttct tcttaggttg gaacattatt cgttgggcat
    12361 tcatgtggta tacacaagaa tttggctaca aagctggttc taaaattact gatgaccttt
    12421 ctggcggatt gttacaagac gtaacaaaag gtgcttcaat tttagggatg ttcgtattag
    12481 ctgcccttgt acaaagatgg gtatcaatca aattcttacc agttgtatca actgtaaaat
    12541 tagataaagg tgcttacatc gaatgggata aattgccttc aggtggtgaa ggaatcaaga
    12601 gtgcatttga acaagttaat aatggcttag ccctttctcc tgaaaaggta acaacattac
    12661 aagacaactt agaccaattg attcctggtt tagctgcatt aggattaaca ttgttatgta
    12721 tgtggttgct taagaaaaag gtttctccaa tcgttatcat ccttggttta ttcgtagtcg
    12781 gtgttgttgg acacgtcatc ggacttttat aatccataaa aatatagctc gggcgttgtc
    12841 ccgagctttt tttatatagt atactgttca taaacaaata tctggaggga gaaaatggtt
    12901 caatcaatca atacaaaagt agacttggta attgatgcta cttcgtttac gggtctgaca
    12961 gattacgggc aaatcatgat aggtgataat ggttttgagt tttaccatgc gcgagataga
    13021 cgcaaatata tccaaattcc atgggaagaa gtggattatg tactagcatc agtcatgcta
    13081 aagggaaaat ggattcctcg atatgccatt caaacgaaaa aaaatggtac atacacattt
    13141 tcttccaaag aacctaaaaa agtgcttcgt gcgatcagag aatatgtaga tgaagataga
    13201 atggtacaat cattgagttt ctttgatgta gtgaaacgtg gtattcgtag tatgtttaaa
    13261 cgcaagtaaa aaataaagaa aacttctaag aggaggtttt ctttattttt ttactttgca
    13321 gaagaaaata tgaaatagca aaaccaatta tttgtcccct ttaaatccca tatgctaaaa
    13381 ttgattagca aagaaggagg ttatattatg agttggttat ggacattgat tgttggagcc
    13441 gtgatcggag caattgcagg tgcgatcacc agtaaaggaa attcgatggg ctgtgtaacg
    13501 aatatcattg ctggactagt cggttcaagt attggacaag cgattttcgg cgaatgggga
    13561 ccaaaagctg caggtatggc acttattcca tctattttag gcgcagtgat tttggtagca
    13621 gttgtctcat ttttctttgg aaaacgatca taagttttta caaaatagta aactaaaagg
    13681 agttgcagcg agactgtgac tcctttttgg ctttatttat ttaaaataaa aagaagtttt
    13741 ccggaaattt ttatttaact gtcgtgtacg aagaaaagtt tgctataatg gaaaaaagcg
    13801 tgcaaagaaa gagggagttt cattatgatg ctacgtgtag aaaaattgcg caaaaaaatg
    13861 caagaagaaa atttggattc atttttggtt accagtccgt acaatcttcg ttacttaacg
    13921 aactttacag gtacgacagg attagctgtt attactttgg aaaaagcatt ttttattact
    13981 gattttcgtt ataccgagca ggcggcagcg caggctcaag ggtttgaaat tattaaaaat
    14041 gtcggaccta tttttgatga ggtagcaaac ttagtacgca aagaagaact gcactcatta
    14101 gcttttgagg aaacaacagt ctcattttta gaatattcgg ttttagaaga aatcatcgat
    14161 gcggaattag tacctgtttc acagatgatc gaagaactca gagaagtgaa agatgaagaa
    14221 gaaatcgcta ttatcgaaaa agcatgtcat attgcggata tggcatatga tcacatcctg
    14281 aaaatgatcc aaccgggcat gactgagatt gaagtcgcaa atcaactaga cttttatatg
    14341 cgttctcttg gcgcttcagg tgtttctttt gatacgatcg ttgctagcgg attgcgttcg
    14401 gctatgccgc atggtgtagc aagcaaaaaa atcatcgaac aaggtgactt gatcacattg
    14461 gactttggtt gctattacga agggtacgtt tccgatatga cacgtacatt cgctattggt
    14521 gatcctgggg aaaaattaaa agaaatttat caaatagtct tagatgctca attagcagtt
    14581 attgatgctg caaaaccagg aatgactggt gtccaattag atgcagttgc tagagattat
    14641 atttcaaaac atggttacgg ggaagcattt ggacattcta caggacatgg gatcggttta
    14701 gagatccacg aaggaccaaa cgtttcttct cgtgcagaaa agcaatttgt accaggaaat
    14761 gtgatcactg atgaaccagg gatctactta ccaggaatcg gtggagtacg tattgaggat
    14821 gacttgttga tcacagaaga tggaaatcgt gtgttgactc gttcaccaaa agaattgatc
    14881 atcttatagt ttcatcaata gaagaagtaa gcgtaaaaat cagtgttcac agactttgtt
    14941 atagaaaatc actcgattta atgatacact atagaagaac ttttaagctg taagagataa
    15001 taaagttggg tgttttctcc aattcatagc agtttgcagc tgatcggcgg cagttttctt
    15061 accacgtgat cactatgccg catcatagag aattcggatg tatctcgtgc ttaggcaaag
    15121 ggaggaataa ataaatggca gatgaaaaaa atttgatttt aaacgcaaac caagatttag
    15181 gagagatcgt gatcgctcct gaagtcatcg aagtaattat cgggattgca gcttctaaag
    15241 tagaaggcgt atacggaatg cgcggaactt ttgccagcaa tgtcactgaa ttattaggac
    15301 gtgcagctca cggaaaaggt gtttacttag caaacgagga agatggcttg aaagtagatc
    15361 tttactgtta tctagaatat ggtgtttcag ttcctaaagt agcaatggaa atgcaggaac
    15421 gggtcagcca gcaagtcctt ttcatgacgg atatcgattt atctgaagtc aatatccatg
    15481 tagtagctgt tgttcctgaa aaattagaac aaccaacaat cgaagaactt tttgaagacg
    15541 aagaggaaga gaatgaataa agaattatca agacacgaga ttcgggaaat ggcattgcag
    15601 gctttatttc cattagactt caatgcagac ctaacaaaag aagatgcgat tttcaacgca
    15661 atcgaattag accaccgcga catgatcaac gaagatgaat cagagtttgt tcctgtttat
    15721 cttgatacgc tagttggcgg tgtctgtgca aaaaaagatg aattggataa agtgattgaa
    15781 aaacatttaa aaaacaattg gcacatcaat cggatctcaa aaatggattt ggtgatcttg
    15841 cgtatcgcga tttttgaaat gacttatgtg acagatgtac cagcggctgt tgctttaaat
    15901 gaagcaatcg agttggcaaa aacatttagt gatgaccgtt cacgtaaatt cgtcaacggt
    15961 gttttatcca atgtattgaa agaattagaa gctggggcgt aagtcctagc ttttttctat
    16021 gaatcatcat aaacctgtta taaatcggga aaattctatg gtagaatgaa aacacaaaaa
    16081 atatctggga gtggttagat ggcagaattg attaacggaa aagaattagc tgaaaaaatg
    16141 caggcagaga ttgctgaaaa aatccaaaaa ttgaaagata atggtatcca tcccggatta
    16201 gtcgttttat tggtagggga aaatccagcc agccaaatct atgtaagaaa taaagaacgt
    16261 gtagcaaaag aaatcggaat ccattcattg gtagagcgtt atcctgagac gatttctgaa
    16321 gacgaactac ttgcagaaat tgaaaaatac aatcaagatc ctagttttca tggtatattg
    16381 gtccaattac cattgccaaa gcatatagat gaagaaaaga tcctgttagc tatccgccct
    16441 gaaaaagacg tagacggttt tcatccgatg aatttaggca gactccttgc gggtaaaccg
    16501 gacaagattc cttgtactcc atacggcatc atgaaaatgt ttgaagctta ttctatcgat
    16561 ccggcgggta aacgagcagt agttatcgga cgaagcaata tcgtcggtaa accgatggct
    16621 cagctactct tgatggcaga tgcaactgtt actgttgctc attctaaaac cgaaaatctg
    16681 gctgaactgg cacaagaagc agatatttta gtcgtagcaa taggacgtgg acattttgtc
    16741 acaaaagaat tcgtaaaacc aggtgctgta gtgatagatg tagggatgaa tcgtgatgct
    16801 aacggtaagc tgatcggtga tgtgaaattt gatgaagtgg agcctattgc aggctggatc
    16861 actcctgtgc caaagggtgt agggccaatg actatcacga tgctgatgta tcaaaccgta
    16921 aaatctgccg aagcttttgg agcaggtgaa tagatggcac aagaatattt aactgtcact
    16981 acattaacga agtatttgaa aagaaaattt gatgccgatc cttatttaga acgcgtatat
    17041 ttaacaggcg aaatatcgaa tttccgttta cgtgccaatg cccatcaata tttcagctta
    17101 aaagatgacc atgcaaaaat atctgctatt atgttcaaag gagcattcca aaaattacga
    17161 ttccagccaa aagaaggaat gaaagtcctt gtcgttgggc gtatttcatt atatgaagcg
    17221 ggaggttctt atcaaatcta tgtagagcac atggagcctg atggaatagg tgctttatat
    17281 caagaattgg aagaacgaaa agaaaagctg atgaaggaag gcctttttca agggcctaaa
    17341 aaaatgctgc cacgtttccc aaagcgaatc gcggtcctta ccagtccaag cggagcggtt
    17401 atccgcgata tcatcacgac ggtgaaaaga agatatccaa ttgtccaatt ggttttgttc
    17461 ccaacagttg tacaaggaaa ccaagcagcg gacaatgttg tcaggaatat ccagagagta
    17521 gaagagatgg gcaatttcga tacaatgatc atcggtcgtg ggggtggttc gattgaggat
    17581 ttatggccgt ttaatgaaga gcgggttgct cgggcgattt atcaagctaa tacgccggtg
    17641 atttcatctg taggacatga aacagatacc acgatcgctg atttagtagc agatgttcgg
    17701 gctgccactc caacagcagc tgcagaatta gctgttcctg ttttgtcaga agagttgatg
    17761 cgcattcaag aacggcaagc tagattgcag caggcgtttg tacgccagat ccagcgcaaa
    17821 caagaacggt tcgagcgtgc tcgacgttcc tatgtatttc ggcagcctga aagattgtat
    17881 gaaggtcaga ccatcaaatt agaccagttg aaacagcgat tatatcaagc tacacagcaa
    17941 atttatcatg cgaaagaaaa acaaacgatc gcattaagcc accaattgga acaagtggct
    18001 ccgctttatc gagttaaagc agctcgccaa gaaactgctt atctagaaaa acgcttagaa
    18061 gagaaaatcc aacaatatat gaaacaacag cagcagcgtt ttgctcaagc tgttcaatct
    18121 cttgatttgt tgagtccatt gaaaatcatg ggaagaggct acagctatac gacgttaaat
    18181 gatcaagtag taaaaagtgt caccgagatt catcaagggg atttgctgac gatccattat
    18241 caagatggaa tcgttaaagg acaagtacaa gagatagaca aaggagaata aaaatatgga
    18301 aaatccaact tttgaagagt cactgcaaga attagaaaaa attgtcatgc agttagaaca
    18361 aggagacgtt ccattagaat cagctctaga ttcgtttaaa cgaggaatgg aattaagcaa
    18421 acattgccaa gatacattag ctaaagcaga agagaccttg acgaaaatga tgacagaatc
    18481 aaatgaagaa gttgattttg acggaaacga ggaaagctga gatgagatta actgactttt
    18541 cagctattca tctacctgct gtagaaaaag aaatcttgtc ttttttagat gagcatacaa
    18601 cggatagagg actctatgat gcgatgagtt attcagtgaa agcaggcggg aaaagaatac
    18661 gtcccttatt acttttaacg gccgttgctt cctttgatga gcctattgat gttcccgtct
    18721 atcaagtagc agctgcttta gaaatggtgc atacgtattc cttgatccac gatgatttgc
    18781 ctgcgatgga caatgatgat cttcgtagag gaaaacctac caatcataaa gtattcggcg
    18841 aagcattagc tatattggcc ggagatggtt tgcttacagg agcattccag ctaatcagta
    18901 tggcacactt aggtaattct cctaagcttc tgctgcttca gcaattagct gtttgtgcgg
    18961 gatcacaagg tatggttgct gggcaagctg cagatatcga gggcgaatcg aaaaagcttt
    19021 ctttagaaga attagcattt attcatgaaa gaaagacagg gcatttgatt cgttatgcct
    19081 tgctggctgg tggcatatta gcgaagcaac ctgaagaaat cttattgcta cttcaacgat
    19141 tagccgaaca tttaggttta gcttttcaga taagagatga tctactcgat gtgattggta
    19201 caacgaaaac attagggaaa acagctggta aagatgaacg tatggaaaaa aatacttacc
    19261 cgcgtttatt aggcctagaa aagacacgtg aggcgttgga gattgagctg ttatccgcca
    19321 acaagatcat agacaaatta gaagaggacg ttttttcttt tgatggcggg ctgatgcgcc
    19381 agatgatcaa gcaatttgat gtggagaaat gagggaaaga atggaaaaag aacgcgtaga
    19441 tgtattagcg gtcaaacaag gattatttga aacaagagaa caagccaaac gttcagtgat
    19501 ggctggtttg atttacaacg aaaaaaacga gcggtttgat aaaccgggag aaaaaattcc
    19561 agtgagtagt gaattaagag tcaaaggtaa aaaacttcct tatgtttctc gagggggatt
    19621 aaaattagaa aaagcactca aagcatttga tctatctgtt gaaggaaaaa cattgttaga
    19681 tattggtgca tccactggcg gatttactga tgcagctttg caaaatggcg caaaaatgag
    19741 ttatgcttta gacgttggct acaatcagct agcttggaaa ataagacaag atcctagagt
    19801 cgtcgtaatg gaaagagtga attttcgtta tgcaaaaccc gaagacttta ccttaggaat
    19861 tccagaagtt gctgttatcg atgtttcttt tatttcacta aaactgatgc tgcctccatt
    19921 acatgctatt ttaaaagaag agggagaagt gattgcttta atcaaacccc aattcgaagc
    19981 aggcagagaa gctgtaggga aaaacggaat tgttcgtgac cctcagaccc atcaaaaagt
    20041 tttagaagac attttgtcat ttgcggcaca aggtggatat gatgtgctgg aattaagtta
    20101 ttctccgatc acggggggag aaggaaatat cgagttcttg gctcacttga ggaaagtacc
    20161 cgaaagcgga acaatcaatt cagctattaa tatggcagaa gtggtttcaa atgcacacga
    20221 acagtttgac cataaataaa ttgtaactgt gaaaatcaag tgagaagtat gcggattctt
    20281 ctttattata ccaaggaaat aagctatcat tgattaagaa gaatatgcta aggagcgaag
    20341 acgtaatgag aaaaaaagat cggcatcgtt tgattactcg attgttgagt gagcaagata
    20401 tccgaaagca ggaagaattt gttgaaatcc tgaaaagcaa aggaatatct gttactcaag
    20461 ctacgatttc cagagatata aaggaactga aactgatcaa ggtaccggct tcagatggcg
    20521 gctaccgtta tagcatacca gctgaaacaa acgaagatgt aaatactaaa ttggaaaaac
    20581 tattaaaaga cgctttcgtg gcagttgacc aaatggaaaa atttgttatt ttgaaaacat
    20641 tgccgggaaa tgcttcggca gcagcaaatt tgattgataa acgttacaag aaagaattat
    20701 tttcgattat caatgatgac gataatgttt tgatgattac acgaactgaa gaccaggcag
    20761 ttttattgaa gaaagacttc ctgcattacc tttaagttga ggagcgaatg tgatgctaca
    20821 agaaatcagt attactaact ttgcgattat tccggaattg cggctttctt ttcacgaagg
    20881 aatgaccgcg ctgaccggag agactggtgc gggtaaatcc attattatcg atgctttagg
    20941 tctgttagca ggaggaagag gttcaagcga ttatatacgt caaggagcag aaaaatgtgt
    21001 gcttgaaggg ttgtttgaac taccaaaaca agaaggattc tctgaactga tggttgaatt
    21061 agggatcgaa acagatgagg acaatctgat tgttcgacgg gatatgtcct taactggaaa
    21121 aaatgtttgt cgagtgaatg gtcatattat cacattagct aatctgagaa gaatcggcag
    21181 ttatttagta gatatccaag gacaaaacga acatcaggaa ctgctccagc ctgaatcaca
    21241 tcttgcttta ttggatcgtt ttggagatgt agctttccaa cagaagaaaa agagttatca
    21301 gcaagaatat atctcttatc gtgagctgga aaaaagggta cgaaaagtgc agcaaaatga
    21361 aaaatcctat gttcagagaa tagatatgct ccatttccag caagaagaaa tagctgctgc
    21421 tgatttgcaa gtcggagaag aagagaaatt aaaagaagaa agagaaaaac ttagcaatta
    21481 tcaaaaaatt gctgatggat tagctgcagg ttacggagca ctgacgaata atgaacaaaa
    21541 cagtgtagat ggtgttggct tggccgtttc agaactgcaa gggatcgccc atctagatgt
    21601 ggagtatgaa gcaatttatg aaaatatcca aagtgcttac tatttgctgc aagatgcaat
    21661 cggcgatatg agtcgtcaga ttgatttatt ggagttagat gagagtcgtt tagaagaagt
    21721 tacgcaacgt ttagaattaa tccgacagtt gaaacgtaaa tacggcgaat ccattgagtc
    21781 aatattggct tactatgacg aaatcaccga agagctagct tcttctgatt tttcagaagg
    21841 tcaattggac aaaatgaaag aggaactaga gcaaaaagag cttctacttc agcaacaagc
    21901 cgcagatctt catgaagcgc gtaaaaaaat cgcaaaagaa ttggaaaaat ccattctgca
    21961 tgaattgaaa agtctgtata tggaaaacac tgagtttgag gtacgtttct taaaagaaga
    22021 aaatagacaa ttgaatcatg atggatttga ccaaatcgaa ttttacatta cgaccaatcc
    22081 aggagagcca ctgaagcctt tggtgaaagt cgcttctggt ggcgaactgt ctcggatgtt
    22141 gcttgctttg aaaactattt tttcttctga gcaaggtgtg acaagtatta tttttgatga
    22201 agtggataca ggtgtgagcg gaagagttgc acaggccatc gcagataaaa tttctcaaat
    22261 atcgaaatac tctcaagttt tgtgcatcac tcatctgcct caagttgctg cagtcgccga
    22321 ctatcaatat tatattgtga aagcagtgat tgatggacgt acgcaaactt ctgtttcaga
    22381 gttgaaaaca aaagaaagag aagaagaaat tgcacgtatg ctggctggaa gtgagattac
    22441 aaaactcaca ctcgaacatg caaaagaact attgaaactc gcaaaaagga cctgagccac
    22501 ctcgcagtgg ttcaggtcct tttcagcagc tgatagctat attttatttt tacatgacac
    22561 tcattacagc agtcaataca acagatccaa tcgttaaaat cagcattgtc caaatgacaa
    22621 attttgttac tttagcaaaa gtacttgttt gttttttttc acgcattgtt ttcaacctcg
    22681 tcattaatta gttgattcaa gtgtacaatc ttttttccat ttccacaaga gggctttttt
    22741 ataaaaactt cccttttttt aaataatagg tagttacgat acaaataaat aatgttaata
    22801 gaactagcca tataaaggca tcatcccttt cagcaatagg taacttaatg ttcattccat
    22861 agatactgcc gacgattgtc ggtatagtta aaataatcgt taaagaagtt aaaattttca
    22921 taatattatt cagattattc gatacgattg ctgaaaaagt ctgattcatt tgttctacta
    22981 gttttaattg aatgcgagaa gtagtcattg cctgctctgt ttccaccaat acatcacgta
    23041 aatgattttt caaagcatga ttttcttgga aaagtttatt ttgcgctagt tctttcaatg
    23101 catctaaatt agcagaagtc gcttctctga aataaacgag gcttttttgg atatccatga
    23161 tttgataaag ttgtttgttt tcagtggata cttgaagttt ggcttccaaa gtatcgcatt
    23221 gagattgaag cgtagctaaa taactgttgt aagagagtgt gacctgccaa atgaattgaa
    23281 agaagatatt gagattaggc gaaatatcac tttttggaaa ggtctggcta aagactttct
    23341 ttaaaaacag tggttcatga ttcgtaattg tgataagctt ctttttgggc gtcaaaataa
    23401 tagagagcgg gtatgtatcc acttgaaaat aaccgctagg acttgtttta gcaaaaggat
    23461 attgtaacaa taataacgct ggctttgtca actttgattg attgaattct tctgtacggg
    23521 aattttctgc atcgtccaat atggaagtga tgtaatctga cggaatttca aattgatgtg
    23581 tcagctgatg aatctcttct tgattaggac gttctacaca ataccagatc gtttggtcag
    23641 tttcctttcc ggtattacgc agtttctcat tatctaatgt aaaatatttg atcatgattt
    23701 tcctcctgtt gcctgtttct tttattataa cggataggga attggaatac atggaatgtg
    23761 tttgtaagat atagaatata actgcataaa tttaaataaa atgaaacagt tgtgtaaagt
    23821 atatacagta tacttgaagc aacgataaaa aaggagttta cgttcatggg cacattcaca
    23881 ccacttatct tgttttggta tatttacccg gtaatcgttt tgtttggttg ccaatttctt
    23941 gtaaaattat tttcgttaaa tcgtcgtttt aaaataaaag cccctgattt ggcgattcct
    24001 tttttgtggg gcggtatgca tgcattgtct agaaatacag ggacaatttc tatcttaccg
    24061 tttttcttta tttctgtttt gctaatggga atttgtattg ctgttttcca agcatattat
    24121 tatgaagaaa ttatttatcc gcgttatttc aagatgactt ggcgtttggt ttttctgttg
    24181 acaatcgtct tgtacgctgt cttgatcatt gtgaacatac tttcttacct atgaaaaaaa
    24241 tagaaaagct gtaaaaagtc ttttaaaagg ctttttgcag cttgattttt aaaaaaatgt
    24301 ttatgaataa aaaaagttgt tcccggattt cccagaaaag gtggtagaaa gtgggggatt
    24361 gtggtagact aattttagtt agtggaggaa tggggggctt tcaatgttga tgggtgaatt
    24421 ccaacataat attgatgcaa aaggacgttt aatcgtgccc tcaaaacttc gtgaagaact
    24481 tggcgaaaag tttgttctga cacgcggatt ggatggctgt cttttcggct atccgatgag
    24541 cgaatgggaa aatctggaag ctaaactgaa cgaaatgccg ttggctaaaa aagacgcacg
    24601 tacttttgtg cgattcttct attcggctgc cactgaatgc gaacttgata aacaaggacg
    24661 aatcaatata cccagcacgt taagaaatta tgcagctttg acaaaaggtt gcgtagtcat
    24721 cggtgtatct aaccgaattg aaatttggga tgagacacga tggcaagatt tttctgcagc
    24781 agcagaagag aactttgacg aaattgctga aagtatgatt gatttcggac tataagaata
    24841 ggaagaggct gactaatgac tgaaacattt caacactata cagtcatgtt gaaagaaacg
    24901 gtagatggat tgaacatcaa accggatggc gtttatgtag actgtacact cggcggtgcc
    24961 ggacatagtg aatatttatt aagccaacta agttctaaag ggcatctgta tgcgtttgac
    25021 caagatcaaa aagcaatcga tcacgccaag ctgcgtttag cttcttatgt cgaacaaggt
    25081 atggtcacat ttatcaaagc gaacttcaga gaattagaag aacgcttgag tgagcatgta
    25141 gataaggtag acggcatttt gtatgatcta ggggtttcct ctcctcagct agatgaagca
    25201 gaacgtggat ttagttatca tcaagatgca ccgttggata tgcgcatgga tcagtcagct
    25261 cctttatccg cttatcacgt aattaatgaa tattcctacc atgaattagt aaagattttc
    25321 ttccgctatg gcgaggagaa attttccaaa caaattgctc gtgaaatcga acgagtacga
    25381 aaaacaaaac caatccaaac aactggtgag cttgtcgaaa tcattaaaca agtcatccca
    25441 gctcccgcaa gaagaaaagg cgggcatcct gcaaaaagaa tttttcaagc tgtgcggatt
    25501 gcagtaaatg acgaactcgg tgccgaagag gcctctttag aacaggcaat ccggttattg
    25561 aaagtcaatg gaagaatcag cgtaatcaca ttccattcat tggaagacag aattgtcaaa
    25621 agtatgttta aagaatatag tacggtacaa gatctaccac cgggacttcc tgtcatacct
    25681 gacgaattcc aaccagaact gaaagtcatt actcgtaaac caatccttcc ttcagaggaa
    25741 gagctaacag aaaacaatcg atcacgcagt gcaaagttac gtattgcaga aaaaataaga
    25801 atgaaagagg agtagaatga tggcagaatt aaagaaaatg caagattacg aatatgattt
    25861 acctgaattg gtggatcagc cggaacaaca aatgcctgat tcttcttcga atcaagaaat
    25921 cattcttcca caatcaccgg caaaacgatt aaagcagatt tctgctttgg aaaaaattgc
    25981 tgtggcaagc gtggcgattg ctattgttgc tttatgtgtt ttaacagtta tgctgcgcac
    26041 aaatatcagc ggagctgaaa aagaaatcac gtcaatacaa acagaaatca atgataaaaa
    26101 gcaagaaaaa acgagtttag aacaagaaaa aaacgaactt tctcgtactg aacggattaa
    26161 acaaatcgca gaagaaaaag gattgtctat taatgacgac aatttaagga aagtgaagta
    26221 aatgagtctt aaaaataaaa ttcggcggtt tatggaaaag aaaaatctaa atccgatgaa
    26281 caatcgcaaa aaagtaggta tcattttatt tgctacgagt attggattgt tctttttatt
    26341 tgccgtccgt ttctcgtata tcgttattgg aggtcatgtt gctggtacct cattagctga
    26401 aaaaacaaaa cagttgtacc aaggaagtga agtagtaaaa gcaaaaagag gaacgattta
    26461 tgatcgtaac ggtgtggcgc tcgcagaaga tgcctcctct tattcaatta aagcgatact
    26521 ctcaaaaaca tatacctctg gggataaaaa actgtatgtt gaagaaaaga attttgataa
    26581 aatagcagaa atcctgcata agaatctttc tatagacaaa aaagatgcac tgaatatttt
    26641 agaggacggc gcaaaaaaag agctgtatca agttgaattt ggtagctatg ggaaaaatat
    26701 ctcccaagaa accaagcaaa acatcgaagc ggacatgaaa aaagaaggtg tcgctggtct
    26761 ttattttgtc gaccatcagg ctcggatgta tccaaatggc gtcttttctt ctcattttat
    26821 tggatacgca gttccagaca aagatgagaa tggcttagtt ggtaaactag gtttggagtc
    26881 tgcttacaat gatatcttga gcggtaaaga tggtaagatt atttatcaaa aagataattt
    26941 tcaaaatcct ctgccaggta cagtggcaga agaagaaaaa gctgtcgacg gacaagatat
    27001 ctacacgact ttagacagca gactacaaag ttatttagaa acactgatgg atcaagtaaa
    27061 tgaagaatat cagccagaag aattgacagc agtcctgatg aaagcaaaaa ccggagaaat
    27121 cttggcaatg ggacaacgac ctactttcaa tcctgaaaca atggaaggat tgactggaaa
    27181 agatgctatc tggcgtaatt tcttggtaca agatagttat gaaccaggat caaccatgaa
    27241 agttttcact actgcagctg ctatcgaaga aggagaattc aacgagaatg aaaccttcca
    27301 atctggaaaa atccaagtag aagatgctac gatcaatgac catgactttg gtgaaaaagg
    27361 tgtgctgacc atgcgtcaag ctctttcatg gtcaagtaac gtcgggatgg tcatactgga
    27421 acagcgatta ggcggacgat ggtataacta tttacaaaaa ctgggatttg gacaaagtac
    27481 tcattctgga ttagatgatg aagtaaacgg tgctttacct acattaaata ttgtcgaccg
    27541 agcaatgagt gcttatggac aagcggtagg tgtgacgaat ttccaaatga tgaaagcttt
    27601 cacttctatt gcgaataacg gtacaatgat tcaacctcga tatatcagca aagtggtgga
    27661 tccccaaact ggagaagagc gaacaactca aacagaagtt ctagggcaac ctttttcaaa
    27721 agaaacaaca gaaaaagtcc gtgaatatat gagagatgtt gtcgaaagcg aaaactacgg
    27781 tagtgcttat ggtgtatata gtgtacctgg atacaatgta tcggcaaaaa acggaacagc
    27841 ccaaatcgct tctgatacag ggggatatca aacaggagat acagcctacc tgtattcgat
    27901 tgtggagatg gttccttctg aagatccaga ctatgtcttg tatctaacaa tgaaacaccc
    27961 taagacatat gatcgaatgg cattggctaa aatcgcaaat ccattgatga aacgggcaat
    28021 ggattttaaa gaaactgaag aagattcaga tacagaaaca aaaacagaaa aagtatccgt
    28081 agccgattat cgtaatcttg aagcggacgt tgcagcagct gatgctcaaa aaagtggact
    28141 gcaacctgta gtgatcggta atggtaaaaa agtacaaaaa caatctactg ccaacggtga
    28201 tcagttgatc tctggagaaa aactgatcct atatactggt ggtgataagc tgatgcctga
    28261 cgtaacagga tggtcaaaag cagatatcat gaagctgggg aaaatcctcg gtattgaagt
    28321 tagttttgat ggagatggtt attgtgtcaa acaagaactt gctccatatg aaaaaatcac
    28381 tgaagacaaa cttagtttta ctttagaaga ataagaagag aaataggaga gaaaagagca
    28441 tggaatggac acaagcattg attcccattg tcagcagttg tgcaatgaca attgccgcaa
    28501 tgccgctatt tattggttat tttcaaatga aaaagcaagg tcaggcgatt cgtgaggagg
    28561 gaccaaagtg gcacaatagc aaagccggaa ctcctacaat gggcggctta gtgtttctga
    28621 tcggctctat tttgacagga atttgggttg gagcttggca aaaacagcta actcctactc
    28681 ttttcatctt gctttttgta ttagcgttat acggagtaat cggctttctt gatgatttta
    28741 taaaaatatt caagaaaaga aacatgggac tgaactcgaa gcagaaattg attggacaga
    28801 ttctaggggg aatcatcttt tatcttgttt accgttctga aggttatcca ggtgtattga
    28861 atttcttcgg actagatcta cctttaggaa tcatttatgg tattttcgct ctcttctggc
    28921 ttgttggatt ttcaaatgca gtaaatctga cagatggcat cgatggatta gttgctggct
    28981 taggaagtat ctcttttgca gcttacggtc taattgcttg gcatcagcat cagtatgatg
    29041 tattaatcat ttgcttaagt gttttaggag gtttactggg tttcttcgtc tacaacagaa
    29101 aacctgccaa gatttttatg ggagatgtcg gttcattagc gttgggcgga cttttagcgg
    29161 caatttctat aatgctaaac caagaatgga cattgctttt gattggtttg atctatgtta
    29221 tggaaacagc aagtgtgatg cttcaagtta cttcctttaa gcttacagga aaacgaattt
    29281 ttaaaatgtc tccaattcat catcactttg aaatgtgcgg atggtcggag tggaagattg
    29341 atacagtttt ttggttgatc agcattgtga cttcgttgat cacattatgg atcgtttggt
    29401 aggagatgac gggaaatgaa aaaaatatca acatatgaaa ataagaaagt gcttgtctta
    29461 ggactcgcaa aaagcggagt aagtgcggcc aaattattac atgaattggg cgcacttgtc
    29521 accgttaatg atggaaaacc ttttgacgaa aatccggaag cacaagagct gctttcttta
    29581 gggataaaag taataacagg tagtcatcca atcgaattgt tggatgaaga attttcattg
    29641 atggtcaaaa atccagggat tccctacagt catcctttag tagcaaaagc ccaagaaatg
    29701 ggtattccgg taattacgga agttgagcta gcttacgaag tagcggaatg cccaattatt
    29761 gggattacag gaacgaacgg aaaaacaacg acaacaacga tgacaggact actactgaat
    29821 gcaggagcag atcaaggaat tgcacgttta gcgggtaata ttgggtatcc agcaagtggt
    29881 gtagcgcaag aagcaaaatc agaagataaa attgtgatgg aattgtctag cttccaactc
    29941 atgggaatca cagatttccg ccctcatata gcggtgatta ccaatatcta tgaagcacat
    30001 attgattatc atggtacaag aaaagaatat gtcaaagcta aatggaacct tcaaaaaaac
    30061 atgacagaaa aagattatct gatccttaac tggaatcagt cagaactaca agaattagcg
    30121 caaagaacaa aagcacgcgt actgcctttc tcgacaaaag aagtgttgga agacggtgtg
    30181 tatgctgacg attactcaat atactataaa aaagaaaaaa taatggaaat atctgaactt
    30241 ggcgtaccag gtaagcataa tgtagaaaat gcactagctg ctatttctgt agcaaaattg
    30301 tatggtatat caaatgaagc tatacgagaa acgttgcatt ttttccatgg cgtaccacat
    30361 cgtacgcaat atgtaggaga aatccaaggc agaaaatttt ataatgattc aaaagcaacc
    30421 aatattttag cgactaaaat ggctctaagt ggatttgaaa cgtctaaggt cgtgttattg
    30481 gctggcggat tagacagagg aaatacattt gatgaattaa ttccttcatt aaaaggaatc
    30541 aaagcaatgg tcgtatttgg ccaaacaaaa gaaaagttga tggatgctgg aaaaaaagca
    30601 ggcatcgaga caatagtaac agccgattct gtagaacaag cagttccttt agcattagaa
    30661 aacagtacag atggtgatgt agttttatta tcaccagcga atgccagctg ggatcaatac
    30721 ccaaattttg aaactagagg aaacagattc atggaagctg tgaaccgatt aaaatagaaa
    30781 aagtagaagc gagcgataaa aaatgaaaat tttggttaca ggcggaggaa cagggggaca
    30841 tatttatcca gctcttgcct ttgtcaatta tgtaaagact caagaaccga atgctgaatt
    30901 catgtatgtg ggagcaaaac gaggtctaga aaacaaaatc gtccctgata caggaatgcc
    30961 tttccatacc ttggagattc aaggatttaa acgaaaaatt tccatgcata acatcaagac
    31021 ggtccgattg tttcttaaga gtatccgtca agcaaaaaaa atcctcagtg attttcaacc
    31081 agatatcgtt atcggtactg gaggatatgt ttccggagcg gtagtgtacg ctgcagccaa
    31141 aatgggtatt ccaacagtta tccatgaaca aaacagtgta ccaggtgtta ccaataaatt
    31201 tttaagccga tatgtggatc ggatcgctct ttcatttaaa gatgcggctt ccttttttcc
    31261 tgaaaacaaa gcagttcttg taggtaatcc tcgagcacaa gaagtagcag atactaaaaa
    31321 atcagatatt ttgaaaacat ttgatttgga tccagaaaag aaaacagtct tgatttttgg
    31381 cggtagtcaa ggagcactta aaatcaatca agcagtatca gtttttttaa gtgaatatat
    31441 tccttcttct taccaagttt tgtatgcttc aggagataga tattatgaag agatcctaaa
    31501 taaaataaat cctgaaatac aaaatattag tgtccagcct tatatcaaaa atatggcaga
    31561 ggtcatggct tccagtgatc tgctggtggg gcgtgctggt gcaacttcga tcgcagaatt
    31621 cacagctctg gggttaccgg cagtgttggt tcccagccca tatgttacga atgatcatca
    31681 gactaaaaat gcaatgagtc ttgttcacgc aggagcagca aaaatgattg cagataatga
    31741 actaacaggt gaatcactaa gtcagacagt caacgaaatc atgggtgatg aagaattgca
    31801 aaagcaaatg tgccgagctt ctaaagaaca aggaatccct gatgcttcaa aacgtcttta
    31861 tgacttagta aaacaaataa tcaaaaaata aaggcggtgg tcttagtgag taagaaaaaa
    31921 gaaccaaaaa aattgtctca tccgtcttct gatgaaaaca atttgactcc ttggcaaaag
    31981 gctaaccgaa aatatctggc agaacaagag atgaaaaacc aagagccaaa aaaagaagac
    32041 ataacattag atacacccct ttcagattct gaagaagaaa aaacggttca agaggaacag
    32101 caagaagaaa gccagtccga gaaaaaaatc gaattttttg aagagatcaa gcaaaagaaa
    32161 aacggtggac catataacgg ttcttttttg aaccggctgc ccaatttaaa aagtcaacgg
    32221 cacaaagtac tatttcgtcg gttagctttg atcatcactg tattgggtat accgctgatt
    32281 tttttgatct attatgtttc tccttatagc aaattacaag cagttgcagt atcaggcaat
    32341 aagacagtca acagccaaga aatcatctct gatacaaaat tgtcattagg agaaaatgtt
    32401 tggggacagt attttcatcg atctacttat atcgatcgcc ttaaaaaagc acagccaaga
    32461 atcgaaacag caaatataca tttcaaaggg atgaatgaat tcgatttgga tgtaacagaa
    32521 tataaagaga ttgctttgat cgcaaaaaac aatcaatact acccagtgat tgaaaatgga
    32581 acagtattag atgaaaaagt agcaaatcct acaaaaaatc tccctatctt ggaagagttc
    32641 aaagactctg caaaaatcaa agaattaaca aagcaataca atcagttatc atcagaatta
    32701 caaaaagcaa tttctgaaat caagtacacg ccaagagcaa gcaataaaaa tctgatccaa
    32761 ttgaatatga atgacggcaa tcaagttatt gtaaatatca ataatcttgc gaaccaaatg
    32821 aaatattatt cgcaagtagc caaagatatg gatgaaaaag gtgtgatcga catggaagtt
    32881 ggtatcttct cgcatcctta cggtagcact caagaaacgg aagaatcggg ccaatcggaa
    32941 gaaacaactg aaagtgaaga aaatgcggat caaacaaacg aatcaagtga agaggcagaa
    33001 acgcaaaaag cacaaacacc tggatcgtct agcacaaacg gatcatctga ttcaaatgat
    33061 tcaagtgaaa caagtcaaat agaagataat ccaagtacaa ctccgtcaag tttaaatgaa
    33121 aattgataaa acaactttaa aaagtaagaa tgtactttct aaaaaccagt aatttatggt
    33181 agaattggaa gcagtgaata tatctattaa taagtatatt ttaaaacgga cgctagttgt
    33241 tcgcttgtat atggaatagt aagtaggagg gaatcccatt catggcaaaa acaggaatgt
    33301 atgtaggcct tgatattgga acgacatctg ttaaagttgt cgtggctgaa tatatcgaca
    33361 gccaaatgaa tattattgga gtaggaaacg caaaatcaga agggattaac cgaggcatta
    33421 tcgttgatat cgataaaacg gtccaagcga tacaacgagc agtacgacaa gcagaagaaa
    33481 aagcaggtat ccagatcaaa ggcgtaagtg tcggtttgcc agcaaacatg cttgaagtag
    33541 aaaattgcca gggaatgatt gcagttaacg gagattcaaa ggaaatcacc gatgaagatg
    33601 tcagaaatgt ggcttcagct gcccttgttc gttcaatacc tcctgaacgt caaatcgtgt
    33661 caatattgcc acaagatttt actgtcgatg ggttcgaggg aatcaaagat cctcgtggaa
    33721 tgatcggcgt aagattagaa atgtacggtc tgttgtttac aggacctaaa acgatcatcc
    33781 ataacatacg taaatgcgtg gaaaatgccg gattaatcgt caacgaaatg gtgattactc
    33841 ctttagcgct gactgaatca attctttctg acggagaaaa agattttggt acgatcgtca
    33901 ttgatatggg tggcggccaa acaacaacgg ctgttatgca tgataagcaa ttgaagttta
    33961 ccaatcttga ccaagaaggt ggcgaatttg tcactaaaga tatctctatt gtattaaata
    34021 cgtcatttaa caatgcagaa gcgttgaaaa taaactacgg ggatgcatac ccagaacgga
    34081 catcaccaga tgaagaattt ccagtagatg tgattggtca gtcagaacca gtgaaagtcg
    34141 atgaacgcta cttgtcagaa attatttcag ctcgaatgga acagattttc aacaaagcaa
    34201 aagatgcatt ggaccaaatc gaagcattag agttgccagg tggcgtcgta ttgacaggcg
    34261 gagctgctag tcttcctggt gttgtggact tggcacaaga aatcttcggc gtaaatgtaa
    34321 aattgtatgt tccaaatcac atggggctga gaaacccggt atttacaaat gtaataagta
    34381 tcgtggatta ttcagcaaac ttgagtgaag tgtatcaatt ggcaaaaatt gctgttacgg
    34441 gtgaaacctc agcagctcgt caaatggtag ttgaacaaga aacaacaaac acatatgaga
    34501 gctatgaagc acctgaagaa acaatctacg atgagccgga accaaaagag tccggagaaa
    34561 atgtaaaaaa taaaatcaag ggtttcttta caaatatttt tgattaattc atcctgggag
    34621 gaataagata tggaattctc aattgataat aatatcaatg acggcgcagt aatcaaagtc
    34681 atcggagtcg gtggtggcgg tggaaatgct gtaaaccgaa tgattgaaga aaacgttaaa
    34741 ggtgttgaat tcattacagc caacacagac gtgcaagcat taaaaaattc aaaagctgaa
    34801 acagttatcc aattaggccc caaatatact cgtggtttag gtgctggttc tcagccagaa
    34861 gttggacaaa aagcggcaga agaaagtgaa caatccttac gcgaagcttt agacggtgca
    34921 gatatgattt tcatcactgc aggaatgggt ggaggaaccg gtacaggtgc tgcaccaatc
    34981 gttgcaggta tcgcgaaaga attgggcgca ttgactgttg gtgtcgtgac acgtccattc
    35041 acttttgaag gaccgaaacg tggccgtttt gctgcagaag gtatcgctcg tttgaaagaa
    35101 aatgtggata cattattaat tatctcaaat aaccgtttat tagaagttgt agataaaaag
    35161 acaccgatgc ttgaagcttt ccgtgaagca gataatgttt tacgacaagg tgtacaaggt
    35221 atctctgatt tgatcacagc gccaggttac gttaaccttg actttgctga cgtgaaaaca
    35281 gtgatggaaa accaaggtac agcattgatg gggatcggtg tggctagtgg agaagatcgc
    35341 gtagtagaag caacgaaaaa agcaatctcc tctccattgc ttgaaacatc tattgatgga
    35401 gctgaacaag tacttcttaa catcacaggc ggtttggata tgacattgtt cgaagcacaa
    35461 gatgcttcag atatcgtagc aaatgcagca actggcgatg taaatatcat tctaggtaca
    35521 tctatcaatg aagaaatggg cgatgaaatc cgtgtgacgg tcatcgcaac aggtatcgat
    35581 gaatcaaaaa aggaacgcaa gtctagccga ccagctagac aagcacaaat gcaatcacct
    35641 gctcaaaaga ctgtattaga tatggatcaa gctaaaccaa cttcttcaga agaagaaaac
    35701 agttttggcg attgggatat cagacgtgaa caaaatgttc gtcctagagt tgatgattcc
    35761 aattttgaca atatcgaaaa aaaagaattt gatacattca accgcgaaga aacaaaatct
    35821 catggcgatg atgaattaaa tacgccaccg tttttccgtc gtaaaaaata aaggagagga
    35881 agagcacatg attgctgaca acttgcagaa aatcaagcaa gaaattcagg attcgtgtgc
    35941 tcttgttcat cgtgatccga aagaagttac attagtagct gtaacaaaat ctgttgaatc
    36001 cgctcaagct gaagaattgg ttagagctgg cgttatgaat tgtgcagaaa accgagtaga
    36061 taaattatta gaaaagaaac aagatttatt tgattttcct gaaataaagt ggcatttaat
    36121 tggtaattta cagcgcagaa aggtaaaatt gattgtaaat gaaattgatt actttcatgc
    36181 gttggacagt ttaagattag cagaagaaat ccagaagcgg ttagagaaag aattatcctg
    36241 ttttattgaa gtaaatgttt ctggtgagga atcaaaacat ggaatttcac cagatgagct
    36301 tttaccgttt gtggaatctt tagctgcctg cacaaaaatc aaggttgttg ggttgatgac
    36361 tatggcgcct aaagaagctt ctgatgagca aatccataaa gtgtttggta cgctgaaaga
    36421 attgcgtgat cttgttcaag caaaaggtta tgcccatgca ccatgtagtg aattaagtat
    36481 ggggatgagt caagactttc aaattgcgat tgaagaaggt gcaacattta tccgtgtagg
    36541 aacagcgcta ttcaaagacg aataaaggag gaacaaaaat gccgctttta aacagaggag
    36601 caattgctaa ttttttcgga ttagctgatg aggaagagta cgaataccaa gattatcctg
    36661 aaacaacaaa aaaggctgta cagccaacta aaaaaaatac aacacagaat caatcaactc
    36721 attctgtatc tgctgcgaat actcatgaaa aacaaaaaac ggcgacttca cgtcctgtaa
    36781 cgcatgaaag tattcagccg gctgaaaaga aaaaagtaat tgaactacat caatcaccta
    36841 caaaaactgt agcgaaagaa agaacagctt caagaacctc tacacaacct aaagcaaatc
    36901 ttgctggaaa aatcactgta atggaaccaa gagcttattc tgaagctatg gcgattgcta
    36961 aacgaatcat tgctggagaa gcaaccttag tgaattttca tttagtagaa gaaaaacaag
    37021 cgagaagaat cgttgatttt ctaacaggaa cagtttatgc actagatgga gatatcaaac
    37081 gtgttggaga tgagattttt ctttgtacac cgactgggat ggagattgac agttcaaccg
    37141 ctcaatcttt tgcagatgcg aatttgtttg atctgtaaga ggaggaacta cgatttatac
    37201 tattgcacta ttacttcatt tacttcaacg ggcagcctat ttctatagca ttatcttgat
    37261 ggtatatgca ttgctctctt ggtttccagg cgggtatcaa tcagggctag gacgattatt
    37321 agctaagatc tgcgaaccgt atatcagttt gttcgatcgt ctgcctttga ggattggacc
    37381 cttggatttc acaattttag gggcaatcct gatcttgaac ttagccgtac aaggtttagc
    37441 acagatcgtt atatggataa ctgtccattt agtttattga ttgaagcaac aaaatcttta
    37501 ttctcagaat agataggagg ggaaaatttt ggatgcaaat gtataccagc actttcgggc
    37561 agatgaacgt acatttatcg attcggtagg cgattggatt gaacaggttc aaggacaata
    37621 tgcaccctat ctgaccgaat ttcttgaccc aagacaatcc tatattttag aaacactgat
    37681 tcgacaaagc agtgatttgc gtttcatgtt ttatggcgga tatgaacagg cagaaagaaa
    37741 aagatgtttg attttccccg attattacga acctgtagag gaagattttg aaacagcatt
    37801 gtatgaaatc cattatccta gcaaatttgc cagcctaagt catgggaaaa tccttggaac
    37861 tttagtggga acggggatca aacgctctta ctttggcgat atcatctcgg acggtgatcg
    37921 ctggcaagta tttattgcaa atgaggtgga tcattttgtt gctgcacaag taacaaagat
    37981 tggaaaggtt gctgtacgct tggaaccaat caaatacaca gaaatgatta tgccgaaaga
    38041 tagctggaca caagaaagag gaacagttag ttccatgcga ctagacagtg tgatctctga
    38101 gatttataat atttccagac agcggtccaa gcagctgatc gaagctggta aagtaaaagt
    38161 gaactggaca gaaaatacaa gacctgattt tgtacttgaa ctattagata ttatttcagt
    38221 cagaggttat ggcagagtcc agatccaaga acttgagggg aagacgaaaa aagaaaagta
    38281 cagggtactg ttcggtgtat tacgtaaata aaataaaaag gtggtttact catggcttta
    38341 actccattag atatccaaaa taagacattc ccgacaaaaa tgcggggata taatcaagac
    38401 gaagtagatg atttcttaga tttagttgtt cgtgactatg aggaattgac tcaaagaaat
    38461 cgagaattag aaaaagcagt caaacattct gaagaaaaac ttgagtactt caatgaatta
    38521 aaagatgctt tgaaccaatc aatcatcgta gctcaagata cggctgataa agtaaaaaca
    38581 agtgcaagca aggaatccga agtgatcgtt acttctgcac aaaacaaagc agatgagtta
    38641 gttgcgaacg ctgaaaaacg tgcacatcaa ttaacaactg atgcagaaga aaaagcaaga
    38701 aaaatcttga cagatgcaac agaaaaagca agacagcttg cgacagaaac tgaagatctt
    38761 aagaaaaaaa cacgagtatt ccatcaacgt atcagcttga tgcttgagtc tcaattagaa
    38821 caagtgaaaa gtccggaatg ggatgaaatt ttacaaccat tctccagcta cgtgactgac
    38881 agccatgaag tgatcaaaga agttttagca aaacagcttg acaatgaaaa tgatactgat
    38941 gtaaactcag acacaggagt catagaagca cctatgacgg catttgatac acaggctatt
    39001 gatatctcga tcgtgcctgg tgaaaatgaa aacgagtaga acagaaaagc actttgttat
    39061 tcttaaagcg agccgatgag agtggaagtt cggtaagaca ctgcatggtg aaagatcctc
    39121 tacttgagac ctgcttttcc gaaattagag taagaagcag cggctgacct cgttattggt
    39181 cacagagagt ttgcactaga tagatgcaac taaatttggg tggtaccacg gcatgttcgt
    39241 cccttgcggc tgaacatgct tttttgtgtc cggaaaacaa ataaaggagt gtatggttga
    39301 atgaaaatga aagaaacctt gcaattagga aaaacaaaat tccctatgcg tggtaatttg
    39361 ccaaaccgag aaggcgagtg gcaaaaagaa tgggaagaaa atcgaatcta ccaaaaaaga
    39421 caagagttga acgaaggaaa acctagcttt gttcttcatg atggacctcc atatgccaat
    39481 ggtaatatcc atttaggaca ttcattgaat aaaatcagta aagacattat cattcgttca
    39541 aaatcaatgt ctggctatcg tgcaccatat gttccaggat gggatacaca tggattgccg
    39601 attgaacaag tattggctaa taaaggcgtg aaacgtaaag aaatgtccat ggcagaatac
    39661 ttggaaaaat gtcgtgaata tgcactttcc caagtagata agcaacgagc agatttcaaa
    39721 cgcctaggag ttgcaggaga ttgggaacat ccttatgtta cattagatcc ttcttatgaa
    39781 gctgcacaag tacgcgtatt tggtaaaatg gctgaaaaag gctatattta caaaggattg
    39841 aaaccaattt actggtctcc gtcaagtgag tcttctttag cggaagctga aattgaatat
    39901 aaagatgtaa aatctccatc tatttttgta gctttcaatg tcaaagacgg caaagatatt
    39961 cttgatgaag atacagcttt tgtcatttgg acgacaacac catggacatt gccagcaaac
    40021 caaggtattg ctgtaaatcc aaaatttacg tatgtattgg tggaagccga tggccgtaag
    40081 tttgtcgtag cgaaagattt gctagaaaca gtccaatcag aaatcggttg ggaaaatgta
    40141 acagttctaa aagaatttgc tggacaagaa atggaatata tgactgcaag tcatccattc
    40201 tatgaacgtg aatcacttgt gattttaggc gatcatgtta ctttagacgc tggtactgga
    40261 ttagtccata ctgctccagg acatggggaa gatgactata tcgctggtag caaatataaa
    40321 ctatctgtag tgtcacctgt agactcaaaa ggattgttta cagaagaagc acctggattt
    40381 gaaggtatct tttatgacaa agcaaatcct atgatcactg atctattaaa agaaaaagga
    40441 gctttgctga agctagattt ctttactcat agttatcctc acgattggcg gacgaaaaag
    40501 cctgtgatct atcgggcaac tccacaatgg tttgcatcta tcgataaatt ccgtcagaat
    40561 attttggatg aagtagaaaa agtagagtgg gttatcccat ggggtaaaac acgtttgtat
    40621 aatatgatcc gtgaccgcgg cgattgggta atttcccgtc agcgtgcatg gggagtacca
    40681 cttccgattt tctatgctga aaatggagaa gcaatcatca caccagaaac aatcgaacat
    40741 gtggcaaaat tatttgctga acatggatca attatctggt ttgaaaaaga agcgaaagaa
    40801 cttcttcctg aaggatttac ccacccaggt tctcctaatg gcgaatttac aaaagaaaaa
    40861 gatatcatgg atgtctggtt tgattctggt tcttctcatg aagctgtttt acgtcagcga
    40921 ccagaattat cattcccagc agatatgtat ttagaaggat cagaccaata tcgtggctgg
    40981 ttcaactcaa gtatcacgac tagtgtggct atcaatggtg tagcaccata caaatcagtt
    41041 atttctcaag gatttgcttt agatggtgaa ggccgtaaga tgagtaaatc tttaggaaac
    41101 atcattgcac cagaaaaagt gatcaaacaa tttggtgcag atatccttcg cttatgggta
    41161 tctagtgtag attatgaagc agatgttcgt gtttctatgg atatcttaag tcaagtggca
    41221 gaagtatatc gtaaaatcag aaatacgatg cgtttcttat tagcgaatac agaagatttc
    41281 gatcctaaaa aagatactgt ttcgtacaat gatttacgtt ctgtagacaa atatatgacc
    41341 gttcgattga accaagtaat caaagaaatc cgagaagaag ggtacgacaa atataacttc
    41401 atgcatattt accgtacagt tatgaacttc ttgacggttg atctatcgtc attctacctg
    41461 gattttgcta aagatgtagt ttatattgaa gcagaagatg attatcaacg tcgttgcatg
    41521 caaactgttt tctatcaaac agctgtagct ttgacaaaat tattgactcc tatcattccg
    41581 catacagcag aagaaatctg gtcattcctg aaagaagaag aggagtacgt tcagttaagc
    41641 gagtttcctg gttatgaaga gtttgcaaac caagaagaat tgatggatac ctggactgct
    41701 ttcatggact tccgtgataa tgtcttaaaa gcattggaag aagcaagaaa cagcaaattg
    41761 attggtaaat ctttggaagc aaaactaact gtttatccaa aacaacaagt tcgtgaaatg
    41821 ttaaaagctt tggatgcaga tattgcacaa ttattgatcg tttcaccaga ctactttgaa
    41881 gttatggcag cagatgaaca agtgccagat aacgctatgg tatttgatga tgttgctatt
    41941 acagtggaaa aagcagacgg ggaaacttgc gatcgctgtc gccaagttcg taaagatgta
    42001 ggagtagatg aaaaacttcc tcatctatgc ggtcgttgtg caaaaatcgt tgaagacttc
    42061 tatcctgaag ctgtagctga aggattcgaa gaaaagtaaa agggaaaagg gggtgtgaca
    42121 tgttctttgt cacaccccct tttgttatca atcgtttaat tttccacgtt cacgatacca
    42181 gttatctggt tgccagatcc attcgaatcc gtctttttca agtagttcga aagctgcttt
    42241 aggtcccatt gatccagctt tgtagttggg aaaatccggt tgtgtttggt cccaagcttt
    42301 tcgaatgaca tccacgatat gccaagattg agcgacttct tcccaatgag agaagttcgt
    42361 tccatcacca ttcaacgcat ctaatagtaa tttttcgtaa gcttctgggc tattttcaac
    42421 catttctgca ctatttctaa attccaattt gattggttcc gtttcaaatc cttgccctac
    42481 ttctttccca ttcaaggata aagaaaatcc ttcagttggc tgaatataga tcgttagaac
    42541 attaggtgga agtgtcgtat cgtcacatgg ttcatcgaca gatgttttga atacattaac
    42601 aggaacttgt ttgaatacga tgttgatccg agtccctttt tcagtcaaac gtttgcctgt
    42661 acgtacatag aaaggaacac ctgaccaacg gaagttatcg atagtgaatt tgcctgcgac
    42721 gaatgtttca gtctctgatt gagcatccac tttgtcttct tcgcgatagc ccttgaattg
    42781 tacaccatcc aattcacctt gagcatattg cccgcgaacg aagttttcta acacttcttc
    42841 ttcgttataa atgcggatag ctttcaatgc tttgatcttt tctgtacgga tttctttttc
    42901 ggaaaatgct actggcggtt ccattgcaag taatgctaca acctgtaaaa tatgattttg
    42961 caccatgtct ttaagtgcgc cactatgatc gtagtagccc ccgcgatctt ctacaccgag
    43021 gttttcgcca aaagtaattt ggatattgtc gatatagcga ttgttccatt gagcctcaaa
    43081 aatattattg gcaaaacgga tagctgagat gttttggatc atttcttttc ctaaataatg
    43141 atcaatcctg aaaatatctt gttctgggaa tacttctctg atttgctggt tcaattcaaa
    43201 agcagactgg taatcagaac cgaacggttt ttctatgatc aaacgattga agccattttt
    43261 tgtcataata ttttgtgatt tcaaatgaga aacgatcgtt ccaaaaaatt gaggtgccat
    43321 agccaaataa tagacacggt taccgtttaa ttgatagtgt ccatctaatc ggtcagacaa
    43381 ttcttttaat gtctgataat gcgttgaatc atttacatca tgggattgat agtaaaaatg
    43441 gcttgcaaag gtagttgctt cttcatctga aggattcaat gcacggattg tttctttgac
    43501 aacttcacgg tagtgctcat cgctccaggg acggcgagcg gttccgatta cagcaaaatg
    43561 ctcgcctaaa tttccttttc tgtaaaggcg gaacaaagac gggtacaatt tacgctgggc
    43621 taggtcacct gtaccgccga atatcgtaaa caatacattt ttttcattag acatgtggat
    43681 acactccttt atattttatc gacaaaaatc gtgctggccg ccttaaagct gacggggatt
    43741 ttctttctat cattttggat agtgatcggt ccttcataag ctgcgatgtc aacgatctca
    43801 tattcttcgt tgatattcag gtcaatagtg actaagtaat ccaacaattc tttttcatca
    43861 agcactcgtg cgatacgcac ttttgtaccg acaggatagg actccaatgt ttgtcggcgt
    43921 tcttcatgga caacttcctc ttttttagga atcgatcctc catgaggaca atgttcagga
    43981 tgattcaaat agttttctaa atgatctgca agatgttccg aagtcacatg ttccaatact
    44041 tcagcatcat catggacttc attccagcta tagtctaaat gttcaactaa aaaaacttcc
    44101 cataagcgat gtttgcgaat cagactgcta gctttttgca gtccgcttgc agtcaattgt
    44161 acaccttgat aaggggaatg ttctacaagc tcttctttca caagtttaga aatcatttca
    44221 ctgacagatg cagctgagac atctagacta gatacgattt gtttattgtt gactttcgtt
    44281 gtatctccac ctagttctaa aatgattttc aaataatctt ctcgatttgg tgtcatattc
    44341 gatcatcctt tcatggtaaa aaaccatcat tagtaagtgt aacaaaaaaa acgttaattg
    44401 actatttttc taaataaaaa acaaaggatt tttagacgtt tttacaacaa aaaacgaaag
    44461 atgatagaga agactcattc tttcgtttat aaaggatata tatatacatt gggagggatc
    44521 tatttttcag ataacaactt atatgaagtg tctgcagatt cgtcataaag agtttgttcg
    44581 ggataagaaa agataagata aaaaccatac tgatcacgta cgactaaacg atattcatct
    44641 atttctacca cagatgtgcc aagagactga ccgttgatca aaaacgtgta atcagatgta
    44701 atctgtaatt gttgtttttg ctggctatca ctaaagaacc atgtaccttg atactttgag
    44761 agtccttctg acttttccgc ttgttttttc tttttcaagt aaataaaact tgagagaacg
    44821 gtaatgagtg aaccaagaaa atagatcatt ttttttatca ccaaatcact cctttatgag
    44881 aaaataatcg catagacata ttctttcttc tttatttcat tgtaccgaat aaaagctaaa
    44941 atttctctaa gactttcgac tggttttttt actgtttttc tacaaattat gataggatac
    45001 atagtaggaa gaaaggtgac ataatttgaa gtatcagcaa gtggaaatag ctttttttat
    45061 tgaccgcccg aatcggttta tagcacattg tatgaaaaaa gacggagaaa taattattgc
    45121 gcatgtcaaa aatacaggta gaggaaaaga ggtcctgata ccaggcgctg aagtggctat
    45181 tgtatttgct cctggaccta aacggaaaac cgcctatgat ctgattgctg taaaaaagaa
    45241 gggtgactgg tttaatatcg atagtcaatt gcctaatcgg ctggcaattg atggtatttt
    45301 agacggcacg atccttttac caggattaac tggtccattt acggtataca agcgtgaagt
    45361 aacttatctt cactccaaat ttgatattta tttagagacg gtggtcggac aaaaagcatt
    45421 tgttgaagtc aaaggtatga cacttgaaaa taaagcgatt ggtgcttttc ctgatgcgcc
    45481 cacactcaga ggattgaaac atataggaga attaacgtat gccgcacaag atggttatgc
    45541 cgcttatgtc ttgtttattg ctcagttcga acatcttcat ctggcaacga tccatgaaga
    45601 aatgcaacca gcactagctg atatggttcg acatgcgcag caaagcggag ttcaaatcct
    45661 cgcctataat tgtcaagtat cggcagatga ggtaactgtc aagcaggcca ttccatttga
    45721 tgtagatatc ccttttgaag atcctataca atagaaagaa ggtaaaataa tgatcaactt
    45781 aggtattatc ggaacaaatt ggattactca tcaatttgtc caagcagctt taagcacaaa
    45841 aaaatatgaa ttgacagcgg tatattctag acatttggaa aaagcacagg aatttggttc
    45901 tcattatgaa ggggatatcg aattcgcaac agatttgaag acttttttca atattactca
    45961 tatggacacc atttatattg cttctccgaa tagtcttcac tttagtcaag ctaagcaagc
    46021 aattttggca ggaaaaaatg tgatagttga aaagccagct ttttcgacgc caaaagaaat
    46081 ggatgaaatc atccatttgg caaatgaaca caatgtgtat ttttttgaag cagcaagaaa
    46141 tatccatgaa tcaggtttta aaaagattgc cgattactta ccattaaaag acgagataat
    46201 cggtgcaaat ttcagctata tgaaatattc ttcgcgctat gaccaagtat tagatggaga
    46261 agaaccgaat atcttctcga ctcatttctc aggtggtgca ttgatggatt taggtgttta
    46321 ccttgtatat gcagctgttg cttggtttgg aatgccaaaa gaagtccatt atttcccaag
    46381 aaagatttct actggtgtag atggtcttgg atgggggatc ttacgttatg agaattttga
    46441 tgtatcgatc cagccaggta aaatcggtga ttcttattta ccgtcagaga tttattttga
    46501 ctcaggaacg ctagtgatga atggagtcaa tgcaattgaa caagcacaat ttcatgatcg
    46561 cgcgcataaa gaaatcattg atttggcggt aacagctgca gaaaatccaa tggcagatga
    46621 agcagaggat tttgccaatg tcatggctca tccgaaagat ccagcttggg gattgttgta
    46681 tgaagagtgg atcgagctag ctagaaatgt gaaccaagtg atttatgatt taagaaaaaa
    46741 tggcggcatc aaattcgatg cagataatga ggaagatttt taatgaacga atttgtacaa
    46801 gtatttcccg aaaattggca gaaaaaatat gaggataaag ggtttatctc accttctctt
    46861 attcaacgag cagtttttca gccactaagt aataaacaaa gtatagtagc ggtttctcct
    46921 acaggttcag gtaaaacact ggcttatctt tggcctctac tactaaacgt ggaaccaggt
    46981 gaagcaagtg cgttggtcat ttttgcttct tctcaagaac tagctattca agtagcagat
    47041 gttgcacgtg aatggggaaa agacaaagag ttgaaagtcc aatctttggt gggcggagcc
    47101 aacgtcaaac gtcagattga gggtttgaag gaaaaaccag aaatcttgat tggtacacca
    47161 ggaagaatat tggaattgat gaaagcaaaa aaaataaaag cacatcaagt gaaaacaatg
    47221 gtatttgatg aagcagacca gctatttgac gctgggaaca gccaaatcat tgatcaaatt
    47281 cttcatcaag ctccaacaga gtatcagcta gctttttttt cagcgacagc agatcgttcc
    47341 cttgaaagca ttgaaaaaat cactgggaaa acgtttgaga caattgacgt gacagcagag
    47401 gacgattctc gaaaaggact gagacattac tttttacgtg taccgatacg aaagaaagat
    47461 gactacttga gacgtctcac gcatatagaa gattttcatg gtctgatttt ctttaatcaa
    47521 ctgactgaat taggcgtaat ggaagaaaaa ttgctgtata gaggtgtacc ggtaggaagt
    47581 ctggcctctg atcagaacaa gctactccga aaagcagcgc tagaacaatt caaaaagaaa
    47641 atggtcagag cacttttgac cacagatgtg gcggctagag gtttagatat tacaggtctt
    47701 ccttatgtag tgaatgcaga agttccgtta agtgaagaag cttatttgca tcgttcggga
    47761 agaactggtc gaatgggtaa tgaaggaata gtaattacac tcgtacaaga taataatcta
    47821 agagatttaa aacggctttt acgtccatca aatataacac ttgaagagat ttttttatac
    47881 ggaggtaagc tgcaaactga gcagccaacc aaagaagatg cagctcctgc agtaaataaa
    47941 aagtatgcga aaactttttc tggaaaggag cagaacccag aatataacaa agaaaaaata
    48001 agaaaaaaag ttaaaaataa atcaaaaaaa gagagaaata aaggagcaag gcgcaaataa
    48061 gcgccttttt atgctatgat tatgaaaacg ggaacaaaat tggttgccag aggaggggtt
    48121 atgtgaaaga acgtcaagaa gagatcttgc agctattgac agaaaaccaa caaggattga
    48181 cagcaagtga tgtagctgag cgcttaacta tcgatcgaag caatgcaagc cgatatttaa
    48241 gtgaactata caaggcccat catattgtaa aaaccgctgg ccgaccagtc gtttactctt
    48301 tgccaacgga aaagtcaaaa tctgatgaag tgcatgtcga ctcttctacg caagtgactt
    48361 ttgaaacact cgttggagaa aatgattctt taaaagtcag catacagcag gcaaaagctg
    48421 cgattcttta tccaccgcgg gggttgcata cgattatttt tggagaaact ggtacaggga
    48481 agtcgatgtt tgctgaatgt atgtatcatt ttgcaatcga ttcagagatg ctttctgcag
    48541 atgcgccatt tgtttctttc aattgtgcgg attatgctca aaatccgcaa ctgctctttg
    48601 gacacatctt tgggatcaaa aaaggggctt acacaggagc agctcaagat agtcccggtc
    48661 taatagccaa agcagacggc ggtatattgt ttttagatga gatccaccgt ttaccgccgg
    48721 aagggcagga aatgctgttt actttcattg ataaaggtat ttaccgtccg cttggagaaa
    48781 gtgcacaagt acatgaagca tctgttcaga tcattggggc gacgactgaa tcttcagaaa
    48841 gtttcttatc tacgttcaat cgacggattc ctatggcaat caccttgccg aatcttgctt
    48901 cacgttcact ggatgagcgt tatgaaatca tctctctttt tatcaaacaa gaagcgaatc
    48961 gtttgaatca acgtatcgat atcgaaaaag aagcgattct tgccttcatg ctttatgatg
    49021 cggaaggaaa tatcggtcaa gtgaaacgag acttgaaact agtctgtgca aaatcttttt
    49081 tacattaccg tactcatcat gagaaaaagc taatcattcg aaaagaagaa ctttcccttc
    49141 aagtacaaaa aggattactg aaaatcaagg aaataccgga acgtctcgac cgattcatgg
    49201 acagcaaaag tcagtatttg acatttgaac caggatttgc tgatgttgtc tggtcacaag
    49261 atccagaacg aaacatgcag gtctataacg atattgagga aaaagtcact tctctttccg
    49321 aaaccggtgt ggagaacatt gatctagaga ccctcatttc aaaagatgtg gatgcttatt
    49381 tccagacata tgtcaaagaa ttgactaaaa gttcgattcc caaagatctt ttgccagatg
    49441 aaatctggcg gttaaccaat caattgtatg atgtggctga aaaacggtta gaccgtattt
    49501 ataatgaaaa agctcgtttt gcttttgctt tgcatctgca aagtacattg gatcgtgtga
    49561 gagaaggtca tatgatcgtc cacccagatt tgaataacgt acggaaaaat tttaagaggg
    49621 aattccaggt agcaatcgat ctttcaacga tcattgaaga agaagaacaa gttgagattc
    49681 cttttgatga aatcggcttt attagtatgt ttctttctat caatctagga gaaagtgagc
    49741 ctgttaaaga aaacaaagta gatgttctca tattgatgca cggcagacag actgcttcaa
    49801 gcatgttgga gatggcacaa gaactattag gaacaaaagt agggaaagct tttaatatgc
    49861 cactggttat ggaagttcaa acaatgtatg aagaagtgtt acaatatgtc aaaaactatc
    49921 aagagcattt gacgaatggc ctactcttgt taacagatat gggatcatta aacaccttca
    49981 gtgatttgat ttatgaagag actggcattc ggacgaaagc tatcacgatg acaagtacca
    50041 tgattgtgat agaagcgata cggatggcaa gtgttggaag aagcttagaa gatatttatc
    50101 aaaatatcca gctttccttt gaatcgatcg tacgtgatca gttcaaagcg gaaaagtctg
    50161 aaactttaca gcgtaaaaaa gccgtaatcg tgacatgctt tactggtgaa ggagtagctg
    50221 ccaaattata tcagcgtatt atgccagtga ttaatcaaaa taaggtagaa ctgatccaga
    50281 tgcagttttt agaacgtgaa tcattcaaaa aacacatcga tgccttattg gaagaatatg
    50341 agatcaaagc aattgcggga acagttgatg ttgattatca aaatatccca tttttttcag
    50401 cctatgacgt ttttgatgat gaaaaactaa atattttaaa gcgtatagct gatgatgaga
    50461 tcccgacagc taaaattgtc gattcacttg ctggatcatt aagcgatgtc ttttctattg
    50521 atgaactgat ccgttcattg caaaagacag ttcagcagat ccagaccgat ttgtcgatta
    50581 tcgtggaacc tggagtagat actggaatcg ttatccattt agccttcatg ttagacggat
    50641 tgatcaaaca agaaagccat cggcaatttg agaaactgtc tattttctca aaaatttatc
    50701 gtttggaaat ggatatcgtt cgggcaaact tgatggcact agaacgaaaa tatcaggtaa
    50761 aaattccaga agatgatatc gcatttctta cacaaatgtt tcttgaaaat aaaataaaaa
    50821 aatgaacaca ctaatcatac tgtttacaca ctaaacatct gtgtgcgcac tataaaaaag
    50881 agctaaaaag catgaaaacg ctatttcagc tctttttttt attggcatgc ttcttgcgtt
    50941 atataaaagt gtaaaaaaat aaaaggagtg ttaaaaatgg caaaaaaaac aatcatgtta
    51001 gtttgttcag cagggatgag tacgagttta ttggtcacaa aaatgcaaaa agcagcagaa
    51061 gaaaaaggga tggaagccga tatttttgcg gtctctgcct cagatgcaga taataattta
    51121 gaatctaaga atgtcgatgt attattatta ggtcctcaag tacgtttcat gaaagctcaa
    51181 tttgaacaaa aacttgcgcc taaaggtatt ccattagatg tcatcaatat gcaagactat
    51241 ggcatgatga acggagaaaa agttcttgca caagcagaaa atctaatgaa ataaatcaag
    51301 tatgcagttg ggggtataac aacgtggaag atcaacaaaa tctagaagcc atcatggggt
    51361 taatcatgtt tggcggtaat gcaaagagcg atgcaatgga agcgattgcg gctgctaaaa
    51421 tcggtgattt tgagttagcg gataggaaaa tcgctgatgc agaagaatca cttatacaag
    51481 cgcatcatgc acaaacagac atgttgacac aagaagcaca aggaaatcat atgcaagtga
    51541 cattattgac tgttcacagt caagatcact taatgacatc tattgcgttt actgatttag
    51601 caaaagaaat catcgaactt tatcgtcgcg tatacagcga ataaatacaa cttctttttt
    51661 gaacggaaga agaaaaattt ttgaacggat tttttatttt gttataagga gaactctctt
    51721 tatataaaaa acttatagga ggaagtaaaa aatgaacgga ctatcaagtt ggatggagaa
    51781 atacatcctg ccggttgccg caaaaatcgg agcgcaaaaa catttagttg ctttgcgtga
    51841 tgcttttatc ggcacactgc ccgcaacaat ggcgggatca gtcgctgtaa tgatcaatgc
    51901 aattattcgt gatttaccgc aacagtttaa cagtacctat gctgacagtt tagcagcaga
    51961 caaaggaatc tttgccgtat tgaatgtcat catcggaatc aatggttttg tctggaacgg
    52021 tacactagca atcgccggat tgatctttgc cttttcttgg gggtataatc ttgcccgagc
    52081 ttatggagta aatgatctag ctggggggat cgttggttta gctaccttga ttcaaggtat
    52141 ttcctttggt ccagcattat cagcagcatt agatgtgaat gttccttcaa atgtcgcaga
    52201 tgcaatcaat agttctgaga ttggtgcaac gattgcagat ggcacactgt cagttggatt
    52261 atggggttgg ctaaaactag atcatttgaa tggaaacgct tattttacag ttatgatcat
    52321 gggagctatt tcagtcatta ttttttgtaa attgatgctt gccaacatta cgatcaaaat
    52381 gcctgattca gtaccaccag cagtatctaa agcatttgca gccattttac cagcgacgat
    52441 cgctttatac gtcattgcta ttatcaatta tatcgtaggt cgtgtagctg atgggcaact
    52501 gatcattgat ttggtgcaaa aatatattgc agagccattc ctaggattat ctcaagggtt
    52561 gggagcagta ttgatcgtca cagtatttgt tcaagtattc tggttctttg gtattcatgg
    52621 accaaatgta ttggcaccag tgctagaggg aatctgggga caagcacaac taatcaatat
    52681 tgatattttc caaaaaggtt ataacggaaa aactggtaca ccagccgtgt tagatgcaat
    52741 cgaagatgga aaagcttata tgtgggtccg cggatcgttc gatgcttttg catggtttgg
    52801 cggatcaggc ggaacgatcg tcttactgat agctatcttg attttctcta aacgtgcaga
    52861 ttatctaaca gtagctaaat tatccattgg gcctggtatc ttcaatatca acgaaccagt
    52921 gatgtttggt ctgccaatcg tattgaatgc aatcatgttt atcccattct tgattgctcc
    52981 agtagtagca acagcaattg gatggacagc tacttatctt ggcctagtcg ctccggtatc
    53041 gcagcaagtc acatgggtag taccgccgtt cttattgtca ttcttagcaa caggagcgga
    53101 ttggcgggca ccgatcgtaa cattagtatg tatggtcgtg actttcttga tttgggcacc
    53161 atttgtcatc tctgcaaaca aaatggaccc tgccgcaggc gaacaacaat aagatgaacg
    53221 tgaggagcgg gacgctttaa gtttcgttcc tcataatgaa ttttcgagga ggaactgaaa
    53281 tgattacaat tgccagtgca atgcaacaag atgaaatcaa agaattgtta gaaggataca
    53341 atgaagaagg aatgactttt acatttaaag aaaaacaagg aatcaagctg ttctttgaaa
    53401 caagtgcaga agatccggaa gttgcggcta aaaaagcaaa ggaactaatc aaagcacagc
    53461 cttggggaac agtcctttat tttcaatcaa cagctgttta gaaaatggtt taaaaagata
    53521 ggatggttga gatgataaaa aacggtttat ttttatgtag tattggttct ttgatcgtgt
    53581 tgtatagttt gaatccacat tcgcaaaggt atgatttgta tagtatggtc acaggtcttt
    53641 ttctaacagg attaggaatc tatttcttca tgaaggggaa aaaaagagaa gaagcaaagg
    53701 agaaaaataa ctaatggaaa tcacgaaaaa attaaatatt ccagcatcgt ttttttacga
    53761 taaagttatg gactctgtcc ttttcgatgt acgtaaagcg accggcaaat cagtaactag
    53821 aaaacagctg aaaaatttgg agtacgtcaa acaattctcg caaaataacc gggctcgcat
    53881 aaaaatcgaa gaagtcattg aaaaccagtc ttataagttt cgtacatcga caacgaagaa
    53941 tgaattcgtc gttcattatc aaatcaaacc attggacgat tcgacctgtg aggttcatta
    54001 cacagaaaaa atggagtctt atggcatgct tcaaaagttg aatgatatgc ttttaggaac
    54061 aatcttgatg tattttaaac ggagacgttt caaaaaaatg ctagatatga tcgaagcaac
    54121 gtattaaatc aatgaaacat ggtactattt agttattgaa aaatgaagta agctagaagg
    54181 aatttttcat aggaagatag atctttcctg cgaatcctca ctagcttttt tgtaggaagg
    54241 ggcagcaaaa tgacaaacaa agtaagagag ctaggtgtat cttcgattga ggaaatgttt
    54301 gatttagcca cttatgcatt taatggggca gatacacctg aaaggcgaga acgttttcgt
    54361 acacttgcgg agaattcttg gaattacgga ttttttgatg aggaggatcg gctaacaagt
    54421 caagtcatgg cgaccccttt tccagtgaat ttttacggac aagagtacct aatggccggc
    54481 attggctatg ttgcttctta tccagaagca aggggacaag gcgggatcaa tcagatcatg
    54541 gaaaagatcc ttgaagattg ccgtgatcgt aaagtaagct tatcttatct ggcgccattc
    54601 tcctatccct tctatcggcg ctatggctat gaacaatcat ttgataaaat cagttatcaa
    54661 ctaaacagtc gtgatgtgcc gtttatcaaa aaaaaatctg gaaaaataaa gcgtatggat
    54721 tttgaagatg caaaagctgc aatcagaaga atttatgaac agatgccgga aaaccaacga
    54781 gctggtctga agcgcgaaga ctggtggtat acgtataaat tcaagcaaaa aggcaattac
    54841 cagtttgctt tgcattttga tgataatgag gaagcaacgg gatatatcgt ttatcagctt
    54901 gcaacgtctt cctttattat tgcggagtgg ggatttttgg atcatgatgc tttttgcagc
    54961 cttgttcgct tcgtaagttc tcacaatggt gcttttgaaa catttgaata ttcatgcggc
    55021 tacggcggta atgatcaaaa ttatctatta gaaaatccat ttgcttctgt aatgatcaca
    55081 ccttatatga tggcgaggat cgtagatatt tctttgtttt tggaaaatta tccatttaaa
    55141 aagagacaag ctgcatttgc cctacaaata gaagaagatc attatgcgaa atggaatgaa
    55201 ggaatcgtgg aagtaacaat cgaaaatgga aaaaatcatc tctcaaaagt agaacaaaca
    55261 aaactcccaa tcgttcgagg aagtatccaa catatcacgc agctattatt agggtatcgt
    55321 aaagtggaag agttggtatt ccaagaaaga atacaggtga caaaagaata tgaagaaacg
    55381 ttaagctcaa tcttgccaca gcaacagcca attcttaatg actatttttg ataaaaaacg
    55441 ggtgatgaca atatttttgt caccaccctt ttgtttttca tttggcattt gaaggaaaat
    55501 gttaaagtaa atcctctttt ttcgtaaatt tgaatttttt gttttctttt gttttagggt
    55561 tttctttttt gtggtcttgg attgcttctt tcgtaatctt ttcccgattt tttttagatg
    55621 aatctaagcg ttctgcgtat actttttctt ttggcttatc attcattgga aaggacctcc
    55681 ctacattatt tcattctacc tctagtttat catctgttaa ggactagtgg aaacgttttg
    55741 cctaacttat aagctgattt ttttagcaga taagcttgca agtaaaaaac aaacaagcta
    55801 caattgattt attgaaattg ttcctgtagc tcagtaggat agagcaatcg cctcctaagc
    55861 gataggtcgc tggttcaatt ccagtcagga acgtataaat aacccctgta tcctttgtgg
    55921 tacaggggtt tgttttgtat ttgtgccaaa aatgtgccaa actagttatc atttttatat
    55981 aaactatcga atacagcatt gattttttct ttatcctgat cttcaagctc tcgaacaata
    56041 tgaagataag tagacattgt agtttctaaa ctgctatgtc ctaaccgttt tgatacgcta
    56101 agtatattta ctccttgata aagtaaaata gatgcatgtg tatgccttag tccatgcaaa
    56161 gtaaattgct tttcaatccc taattctttt aattttttgc gcaaatattt gctgacggca
    56221 tttgatgaaa ctaatccatt ttttaagttg aaaaaaacaa aattatgagg gtttttaact
    56281 tcaaaattct cgaataattc tttttgattg attttaaact tttttaagag atcaatcgta
    56341 tgtttatcaa ttgaaatttt ccgatttgaa gtctcgtttt ttgtttttcc ccattcattt
    56401 aatttataat tccatgtttt attaatagtg atgatttgat cttcgaaatc gatatcttcc
    56461 catgttaatc ctagaagttc agcaaatcgc attccagtag caccagcaac taacacgagc
    56521 ataggagaag agtactgtgc agaaaggttt tcttctacga gtttcattaa agatttaaat
    56581 tgatcataat ctaaatattt atcttctttt ggcttcaatg aatcttttcc tttgattact
    56641 gcttttctag ttggatcaaa cggaattaat ccttcttcta cggcatcttt caacgatgct
    56701 ctaatatggt tattaaactt aataacggtg gattttacat ggtctttcgc atacttattt
    56761 aaaaagcgtt gatatccaac tctatctaaa tcagaaatca atactgctgg catatatttc
    56821 tttatattca ttaacgtatc ttcgtatttt ctataagtga taggagatac tgttccttct
    56881 ttgtagagtt gcatccaatc ttcaaagtaa tctgataata atagattttt gcgatcccct
    56941 ttaagacctt tattcaggtt atattctaat tcgttggcgg catcttttgc ttcgcctttt
    57001 gtcttgaatc ctgattttct tatcttcgtg tattttccgt catctttttt gtatgaaatt
    57061 tcgtattgcc aactatttcc acgtttgact aatcttgcca taattgaatc tactctcttt
    57121 ctctgataca ataggcactg taaagaagcc tattgtgtag gtttgttttt aacgcgtcca
    57181 caaactttgg cgagggaggg ggcgtgtttt ttatttatac tctgttgttc ctgcttcgcc
    57241 aatcggctca gctgtaaaat catcagtaaa ttgtttagac gcattaagtt taaatgtact
    57301 taaatttggt ttatttttag aaagtaaata gaaaacccca gatgttgtcg tttcaggttg
    57361 aactaaagaa ttagaatttt cgtcatataa gaaatattct ccagctgttc tactatattc
    57421 cataccgtct ccatctatta aagatgcctg atacgaagac aaagagaaag gtgatgttgc
    57481 tttatttttt aacttgtaag aaatagtagt acgatagtat ttttctggaa aattttctat
    57541 tccactaaag ttatattcgg catttgtaaa attatcttcg tcatttgtta cctgttcagt
    57601 ttttatagaa gaaattgtat attctaggat accaacaact ggcaaggttt tttccttaga
    57661 agcattgtcg atagattcgc tattttcttc agtgtcattt gactgcgatg ctatttgttt
    57721 tttaagctct tcattttctt tttttaaact attgattgtt ttttgagttt cactattagt
    57781 tgcattattt gaaggcgaac tacatgcacc caaagttaaa atactagtac aaataaatcc
    57841 taatattaag ttttttttca tttttaattc ctcacttcta tgatattatt tttatgtaga
    57901 atcttagaaa tgagatttta gtccgtgttg cagcacgggc ttttttcttt ataacttttt
    57961 agaggttata ggcaagatag tgggacacaa aaatatatta ttgtattccg tatttagaaa
    58021 atcctaattg aacttcaccg gaagtttttt gctgtgttgt acgcaatgct tcttcttcag
    58081 acattccatt ctgtactttc catgcaacag gcgacatccc gtatttgtta acaaaatcag
    58141 taagtgataa agtgtcagcg tcttgttgag cgcttgtttg ttgggcttct gtattttgtt
    58201 gagatgcagc ttgttgttct ttctgatctt gactgataat attgccagca tcatctgtag
    58261 tcaatccatt ttcataaagg gccacgccga aagcttccca ctctttgttg gaccaatttg
    58321 cacgatcagc tggagttgac tgtaaagtgc gttgtttcat ctgttcatat gtttcttctt
    58381 gaggtgcggt ttggattgta tcctgactgg agcttataac tgttgggcta ggtttcgccg
    58441 tagcttggtt ggagcttgta actgttgaac tagaatctgt tttagatgta gatttgctag
    58501 tagatgaact gatttcagtt gtttcttttg ttttacttat atttgtttct tggttagaag
    58561 tggcatctgt tgattcagct tttttattat ttgaacaagc tgaaagtagc agagcagtac
    58621 ttaacaacaa cataacgcta acttttttca ttttataatt cctctttctc gttgtaatat
    58681 gtgtgctaac acgggctttt ttatataaga aaacgataag cgctttctgg aagaccgtaa
    58741 agattcttta attcctcgat ttttttagga tattgatcat tatcttcttt ataaagagaa
    58801 acaatgagat tagcagcaaa gcaattagct tcgctttcag atttgcttct agatgttctt
    58861 gttgatacat aatagctgga taagccacga tgaaaaatag cgtgacctaa ttcgtgagcg
    58921 caaatgtaga atctttcctc agagtctcgc agttcatcat ttaaaaagat tatcgcacga
    58981 tctctaattt cttgaaactg ccccttggga ttctcgataa aaggaacgta ttgaatttta
    59041 atgcccatct tttcacaaat ataaaaagga ttagcggact ggtatttccg cttcaactcc
    59101 tcgactaaat taatcgtatc catctccata agctcacatc tttttgcctt tttctttgtc
    59161 ttctttcaca atatcccaga aagtcgctat caggatatct tttacgcgct gtatttgttc
    59221 gggtgtcaat gtttccccac cataagacat attaacattt gagtctagta gtttatcaag
    59281 ttcaaccact tcctcttttg tagcccattt gggaacatta ttatttccca ataaataatc
    59341 agttgtgaca ccaaaataat cagcaacttt ctttaagttc tcagattttg gcgaggcttt
    59401 atcccatctt cttatttgtc cattagagat gcccacctgt ctttctactt ctgctatagt
    59461 cacatgcttt tcgtctgcta attctttaat cttagtaact aaactcatta ttatcaacct
    59521 ttcaaagctg aaaagaaaat aaatagctta aaagttatat ttttggttga caattagctt
    59581 ttaagctagt atatttaatt cgtaagctaa attgttagct aaataagagc aacaaaaaac
    59641 tctactaatt taaaacattc tctcggtcgc caaacttaga aatgttattt tagaggcttt
    59701 ttataagtct tatttaacta tgtattcata atagcttaaa agctaatagg tgtcaacgat
    59761 ttagctaatt ttttagctta caaattattt tttagaaagg agctattttt atgtctgaga
    59821 atttagactt aaaaattcga gcggagatga gaaaaagaag aatgactttc aaagaactag
    59881 ctgcgcttgt tggtatttca ggagcttatt tatcagatat cctaaacggc aatcgtgatg
    59941 gtaaaaaagc tcaagaacac atagaaactg taaaaaaaat attaggtatt caataggagg
    60001 aacagctaat gcaatatcta gaagcgaaaa tcccagttcc agaaggctat gtaattatct
    60061 ctcaagtgga ttacgaggag ttaaaaaaag ctgatgatac tggtagatgg atgacgttgc
    60121 cagaagtgct agaacggatt aacagaaaat atgattggtt tacttctaga gttttaaaga
    60181 acccaagata tagaaatatt atcgatatcg agaaaaacaa aaatggattt gtctattatc
    60241 cagttgaagg aagagacaca tatctatttt taagaagtaa aacacttgaa tttttagaaa
    60301 caaatttttc ggaaatctta aggaggcaag cggatgggaa aatttaatag agcgctagt
//
LOCUS       DARBDN010000008        59408 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000008 DARBDN010000000
VERSION     DARBDN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.008"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="SCH06_000525"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="SCH06_000525"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEG1077127.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="SCH06_000526"
     CDS             complement(1172..1867)
                     /locus_tag="SCH06_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEG1077128.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="SCH06_000527"
     CDS             complement(1880..2596)
                     /locus_tag="SCH06_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEG1077129.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="SCH06_000528"
     CDS             2926..3534
                     /locus_tag="SCH06_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HEG1077130.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="SCH06_000529"
     CDS             3859..4182
                     /locus_tag="SCH06_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEG1077131.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="SCH06_000530"
     CDS             4364..5734
                     /locus_tag="SCH06_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEG1077132.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="SCH06_000531"
     CDS             complement(5864..7165)
                     /locus_tag="SCH06_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEG1077133.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="SCH06_000532"
     CDS             complement(7519..9477)
                     /locus_tag="SCH06_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEG1077134.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="SCH06_000533"
     CDS             complement(9654..9920)
                     /locus_tag="SCH06_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEG1077135.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="SCH06_000534"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="SCH06_000534"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEG1077136.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="SCH06_000535"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="SCH06_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEG1077137.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="SCH06_000536"
     CDS             13264..13827
                     /locus_tag="SCH06_000536"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEG1077138.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="SCH06_000537"
     CDS             complement(14080..14601)
                     /locus_tag="SCH06_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEG1077139.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="SCH06_000538"
     CDS             complement(14604..15446)
                     /locus_tag="SCH06_000538"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEG1077140.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="SCH06_000539"
     CDS             complement(15439..16164)
                     /locus_tag="SCH06_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HEG1077141.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="SCH06_000540"
     CDS             16340..16636
                     /locus_tag="SCH06_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077142.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="SCH06_000541"
     CDS             17204..18796
                     /locus_tag="SCH06_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEG1077143.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="SCH06_000542"
     CDS             18809..19549
                     /locus_tag="SCH06_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEG1077144.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19717..21066
                     /locus_tag="SCH06_000543"
     CDS             19717..21066
                     /locus_tag="SCH06_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1077145.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21194..21784)
                     /locus_tag="SCH06_000544"
     CDS             complement(21194..21784)
                     /locus_tag="SCH06_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEG1077146.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            22020..23099
                     /locus_tag="SCH06_000545"
     CDS             22020..23099
                     /locus_tag="SCH06_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1077147.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
     gene            complement(23272..24879)
                     /locus_tag="SCH06_000546"
     CDS             complement(23272..24879)
                     /locus_tag="SCH06_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEG1077148.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKRKFQV"
     gene            complement(24894..28415)
                     /gene="mfd"
                     /locus_tag="SCH06_000547"
     CDS             complement(24894..28415)
                     /gene="mfd"
                     /locus_tag="SCH06_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEG1077149.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(28432..28992)
                     /locus_tag="SCH06_000548"
     CDS             complement(28432..28992)
                     /locus_tag="SCH06_000548"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEG1077150.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            29345..30319
                     /locus_tag="SCH06_000549"
     CDS             29345..30319
                     /locus_tag="SCH06_000549"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEG1077151.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            30489..31889
                     /locus_tag="SCH06_000550"
     CDS             30489..31889
                     /locus_tag="SCH06_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HEG1077152.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(31967..32689)
                     /locus_tag="SCH06_000551"
     CDS             complement(31967..32689)
                     /locus_tag="SCH06_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077153.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(32768..33274)
                     /locus_tag="SCH06_000552"
     CDS             complement(32768..33274)
                     /locus_tag="SCH06_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEG1077154.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            33397..35196
                     /locus_tag="SCH06_000553"
     CDS             33397..35196
                     /locus_tag="SCH06_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HEG1077155.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(35264..36838)
                     /locus_tag="SCH06_000554"
     CDS             complement(35264..36838)
                     /locus_tag="SCH06_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEG1077156.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(37093..37602)
                     /gene="mreD"
                     /locus_tag="SCH06_000555"
     CDS             complement(37093..37602)
                     /gene="mreD"
                     /locus_tag="SCH06_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEG1077157.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(37606..38460)
                     /gene="mreC"
                     /locus_tag="SCH06_000556"
     CDS             complement(37606..38460)
                     /gene="mreC"
                     /locus_tag="SCH06_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEG1077158.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(38615..39253)
                     /locus_tag="SCH06_000557"
     CDS             complement(38615..39253)
                     /locus_tag="SCH06_000557"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEG1077159.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(39254..39904)
                     /locus_tag="SCH06_000558"
     CDS             complement(39254..39904)
                     /locus_tag="SCH06_000558"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEG1077160.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(39917..40816)
                     /gene="rsgA"
                     /locus_tag="SCH06_000559"
     CDS             complement(39917..40816)
                     /gene="rsgA"
                     /locus_tag="SCH06_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEG1077161.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(40981..43050)
                     /gene="pknB"
                     /locus_tag="SCH06_000560"
     CDS             complement(40981..43050)
                     /gene="pknB"
                     /locus_tag="SCH06_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEG1077162.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(43047..43787)
                     /locus_tag="SCH06_000561"
     CDS             complement(43047..43787)
                     /locus_tag="SCH06_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEG1077163.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(43800..45158)
                     /gene="rsmB"
                     /locus_tag="SCH06_000562"
     CDS             complement(43800..45158)
                     /gene="rsmB"
                     /locus_tag="SCH06_000562"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEG1077164.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(45158..46096)
                     /locus_tag="SCH06_000563"
     CDS             complement(45158..46096)
                     /locus_tag="SCH06_000563"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEG1077165.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(46089..46580)
                     /gene="def"
                     /locus_tag="SCH06_000564"
     CDS             complement(46089..46580)
                     /gene="def"
                     /locus_tag="SCH06_000564"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEG1077166.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(46595..49003)
                     /gene="priA"
                     /locus_tag="SCH06_000565"
     CDS             complement(46595..49003)
                     /gene="priA"
                     /locus_tag="SCH06_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEG1077167.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(49256..49561)
                     /locus_tag="SCH06_000566"
     CDS             complement(49256..49561)
                     /locus_tag="SCH06_000566"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEG1077168.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(49566..50180)
                     /gene="gmk"
                     /locus_tag="SCH06_000567"
     CDS             complement(49566..50180)
                     /gene="gmk"
                     /locus_tag="SCH06_000567"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEG1077169.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(50667..50951)
                     /locus_tag="SCH06_000568"
     CDS             complement(50667..50951)
                     /locus_tag="SCH06_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077170.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(50969..51859)
                     /locus_tag="SCH06_000569"
     CDS             complement(50969..51859)
                     /locus_tag="SCH06_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HEG1077171.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(51879..52097)
                     /locus_tag="SCH06_000570"
     CDS             complement(51879..52097)
                     /locus_tag="SCH06_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEG1077172.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(52067..53767)
                     /locus_tag="SCH06_000571"
     CDS             complement(52067..53767)
                     /locus_tag="SCH06_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HEG1077173.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            54034..54807
                     /locus_tag="SCH06_000572"
     CDS             54034..54807
                     /locus_tag="SCH06_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077174.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(54888..55457)
                     /gene="thiT"
                     /locus_tag="SCH06_000573"
     CDS             complement(54888..55457)
                     /gene="thiT"
                     /locus_tag="SCH06_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEG1077175.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(55523..55625)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(55631..56602)
                     /locus_tag="SCH06_000574"
     CDS             complement(55631..56602)
                     /locus_tag="SCH06_000574"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEG1077176.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(56696..58069)
                     /gene="glmU"
                     /locus_tag="SCH06_000575"
     CDS             complement(56696..58069)
                     /gene="glmU"
                     /locus_tag="SCH06_000575"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEG1077177.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(58572..59390)
                     /gene="purR"
                     /locus_tag="SCH06_000576"
     CDS             complement(58572..59390)
                     /gene="purR"
                     /locus_tag="SCH06_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEG1077178.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
BASE COUNT        16697 a        12599 c        11143 g        18969 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagtcattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaaataaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg
    19681 aagtaattaa acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag
    19741 cgtggactga aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg
    19801 ttgtttttag gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat
    19861 cttattactg gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca
    19921 aacaccaata accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct
    19981 ttcatcactg gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca
    20041 gccatcggaa tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg
    20101 attgcattag gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta
    20161 gagttttggt ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct
    20221 tatatgatcc tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg
    20281 tctcatggcg gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta
    20341 acctttgctt ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct
    20401 gaaaaagtgt tgccggaagc tatcaataat attcctatca ggatcatctt attttactta
    20461 ggatctcttt ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt
    20521 ccatttgtag aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta
    20581 gtcgtattaa gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg
    20641 cttcgttctt tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat
    20701 catgtgccag ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg
    20761 aattacgtga tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc
    20821 ttgtttatct ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc
    20881 aaaaaagctc attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt
    20941 tacatggcct ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta
    21001 ctaacacctg tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag
    21061 aagtaagaaa gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga
    21121 aaattgcttc ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt
    21181 cccagcctct tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat
    21241 aggaaaaaat ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa
    21301 aaaagacacc ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct
    21361 ttgacaaaac tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca
    21421 agataccaaa agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa
    21481 aagcttcagg gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga
    21541 gcaaaaagat attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac
    21601 gatgatggtt cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg
    21661 tatttcggat gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata
    21721 caataactct caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg
    21781 tcacgatgat tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat
    21841 aaccatcgtt ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt
    21901 acttttaaaa aaaggcggat tttataatta acttagccat ttggaaataa aaaaacgcca
    21961 cgtgaattcc atgttatatt gaagttacca caactctcaa tagacaagga tgaattcaca
    22021 tgacgcaaaa ccatgataac acagtttcac gcaagggaaa acacctaacc tactcagaac
    22081 gttgccaaat cgccatcctg aaaaaggaaa actattccaa ccgtcaggtt gcggatgtcc
    22141 tgggctgcgt gccgcagacc ataaacaacg aaatcaaacg cgggaccgtt actcagctta
    22201 accgccagaa tcagaacggg aaggtctacg actattatca tgacgtctac gacgccgatg
    22261 ccgggcaggc ggcctacgag aagaaccgct tgaactgcgg cagacggccc ttatgggccg
    22321 acacggacgc cttcattgaa tgggcggacg acatgatgct gttggaaaaa tggtccccgg
    22381 acgtggtggt gggctttgcc agaaaacacg aattgttcga cccggccatt atccctggga
    22441 ccaccaccct ctatcagtgg atcgaccgtg gcatcatgaa aacgaagaat atggacctgc
    22501 tagaaaaact gtcccgcaaa ccgaaatcgt cccgtcatgg caaccgcccg aataaacggg
    22561 tgctagggaa atccattgaa gagcgcccgg aggcggttgg tacccggaaa accttcggcc
    22621 attgggaagt cgacacggtc gtaggaaaca agaccaagtc ggatgccgtg ctgctgacgt
    22681 tggtggaacg gcagacacgc ttcgaggtca ttctgaagct ggccgggaag gatgccgaat
    22741 cggtcaacca agcggtccga cagctgagag aacgggctgg tgcgtacttc ggccagctgt
    22801 tcaagacggt tacctcggac aacggctcgg agttcgcggg actgcacgat gccttgcagg
    22861 atgtggcaaa catctacttc agccacccct atgcttcctg ggagcgcggg acgagcgaaa
    22921 accaacacaa gctgattcgc cgtttcatcc ccaagggcag cccaatcggc aacgtgagcg
    22981 aaaaccaaat cttgcggatt cagcgttgga tgaacgatta cccgcgaaag attttgggct
    23041 atgcaacgcc gcatgacacg ttcgtccagg catttaggca ggaacggttg acggcttgac
    23101 acgtgggccc ttgacaacga gcctccctcg gcatggcttg tgtctggaaa gctggccggg
    23161 gccagccagt cgggagacta ccatgcctca gctcattgtc aagggcccac tcgattagaa
    23221 aaattagacg gttggtggta acgagcaacc gggtcaccat gggtggctaa cttaaacttg
    23281 aaatttacgt ttaatttttt tatttaatcg caggattttc ttaccaaaag gcaacattag
    23341 ccattctcgt actgtaaaca gacgaagacg aatcactgca taaatgaaca cagaagcccc
    23401 gatcccaact cctatcacgc tgacaaaaaa agcagtggaa cgatgagtta caggaccaaa
    23461 tactatattc aatacaccat aatacagcag cagtactact gtcatacaaa gaaggctgaa
    23521 catcaacttc cgtccaaaat gccgttcttt ccaaaaagca tttagctctt ttgtttcaat
    23581 tcgaacaaaa taccaaagcg tcacacctaa tcctaaaagg gtagacaggc ttgcacctgc
    23641 tgttcctaat aaaccggtca gaaaagaagt agtcaatcct tttaccaata gtccccatcc
    23701 tgcgcctttt aaagaagggc gaaacgagtt cttgctttga gcaatacttt gataagcttg
    23761 gatgactgca gtgaaagcaa tggaaaaaac aaataataca agcgctgcat ttcccgcata
    23821 atctttaaac aacgcataat tgatataagg gagcagcaag gctaatccca aagacgcagc
    23881 taatgctaaa gcggtcgtca atctaagata gattttggct gtctgtaaaa actgacgata
    23941 gatccggttg gtcaaatgac gagtcaacgc aggcaggaat gtcgcactta atgcagtggc
    24001 aatcactaaa cctaattgta ctaaaggctg acctcgatca tagacccctt ttgctatctt
    24061 cgcaccgtat tctgacagtc cgtaaacttc caaagcattt tttacaaaga aagagtcgat
    24121 cagctggaaa aagataagca atccactata aatcgaaacc agtccgcctt ctaccagaaa
    24181 acgccggatc aagggctttg acggctgttt gaacaatgga aaccgtcgga agcttaacgc
    24241 tcctccatga atcttttgtt catagtagtg aaggatccca tatgcgcata aaccgccaaa
    24301 aacagctcca ctcattgctg ccgtccctgt ttggtacacc gtccatccaa gctttctaaa
    24361 agcaaacgca ctacagacaa tcacaaaaac acgaacgaac tgctcaacta cttgagaaac
    24421 agcagttggt tccatcaaga atcttccttg gaaattccct cgataaaaag atagaccagg
    24481 catcagcaaa aaggtaaagg aaactacttg gatcagcggt ttcaattgta tgtctcccat
    24541 catccaagca atccagctgc taaatgcaaa gacaaacaac cacaaaaaga cacctgtcca
    24601 aaatactaag ggataaagat tttgcaaagc ttgctttcgc tcgaaaggat tctttctttc
    24661 tgcaacgtac tttgatatga actgcggaag accggataaa gctaaagtca ttgctatccc
    24721 ataaattgga taaacttgct gataaacata aaaaccttcg tcgccgacta agttttggag
    24781 gggaattcgg taaagggcac ttaatacttt tgctatgaaa gaagcaatcg tcaatacaaa
    24841 tgctccttgc atgacgcgcc gcatttcttt atgatccaaa tcattgctcc ttcctacgct
    24901 gacagatatt tttgctcacg caacgctttg acaaactttt ggatttcctg aagccatact
    24961 gcttcttcca tttggttggg gatcgtcaag cgtatcacca tctgttcttt ttcaacgcct
    25021 agactggctt ttagttttgt cgctgtcagt gcttcgaata actgttccac actatagcgt
    25081 tttgttccaa ctttacttag agtaaagact atatgcgcct cctgtttcct tatcgtttct
    25141 aggagcgctc gatcgccatc cattttgatc tgcccaattg tcaagagatg tgctacttct
    25201 tctggatatt ctccaaaacg gtcgagcaga tcatcttcta gttcatctag catttcttgc
    25261 gaatcaagtt cacgaattcg tttatagatc tcgattttct gccgttgatc tgccacgtat
    25321 gtttcaggta gatacgcatc gacaccgagg tcgatctcaa cagtggtctt ctccacttga
    25381 ctattctttc cttgtttacg agaaacagct tcgcttagca tttgagaata catatcgaaa
    25441 ccgactgcat caataaatcc atgctgctga gcacctaaga gattacctgc accgcgaatg
    25501 gaaagatccc gcatcgcaat cttgaatcca gatcccagtt ctgtaaaatc tttgattgcc
    25561 tgaagacgtt tttcactgac ttcgttaagg atcttctgct gctcatacat aaagtaagca
    25621 tatgcgacac ggctgcttct tcctacccgc cctcgcaatt ggtataacgt ggataatccc
    25681 atataatcag cgttctcaac gaacaacgta tttgcgttcg ggatatctac tcctgtttca
    25741 atgatggttg tagtgacaag aacatcatat tgaccttcaa taaattcaaa aagcgtattt
    25801 tctaattgcg cctctgtcat ttgcccatga gcataaccga tccgtgcttc cggaacgagt
    25861 tcttggattt cttctacttt ttgttcgatc gtttctaccc gattatataa atagaatact
    25921 tgtccacctc gtcccatttc tcgatggatt gcttcgcgaa tagccccagg atttttttcc
    25981 ataacatacg tttggatcgg ataacgattc gcaggcggtg tttcgattac tgaaagatcc
    26041 cgcacgccta acatcgacat atgcaaagtt ctcggaatcg gtgttgcagt cagagtcaaa
    26101 acatccactt gtgcacgtaa ctgtttcaat cgttccttat gttttacacc aaaacgttgt
    26161 tcttcgtcaa tgatcagtag acccaaatcg ctaaattcaa tatcttttga caaaattcgg
    26221 tgggttccta caacaatatc aacttgacct gtacgcagtt gttcgatggt ttctttttgt
    26281 tgctttcttg ttctgaaacg acttaatagc ccgatattta cggggaaacc ttcaaatctt
    26341 tccagcatcg tttcatagtg ctgctgtgcc aagatcgttg ttggaactaa aaaggctact
    26401 tgtttgcttt cctttatcgc tttaaaggcc gctcgaagcg ctacttctgt tttcccataa
    26461 ccaacatcac ctacgagtag tcgatccatt ggtttttctt tttccatatc ccgtttgatc
    26521 tccgctgcac ttctcaactg gtcatcagtt tcagagtagg ggaaggcatt ttcgaattct
    26581 ttttggtagg cgtcatcagg tccaaaagca tatccttttt ctgactctct tgcggcatat
    26641 aatttgatta gatcgtcagc gatatcctcg atttttgaag agacttttcg cttggttttc
    26701 gtccattcac ttccgcctag cttattgatg cgaggcgctt tggcttcaga ggcgacatat
    26761 ttttggatca gattcagttg agtaacagga ataaacagtt tgtcgtcgtt ttgatacaaa
    26821 atagtcatat agtcttggtg aacgccatct acttctagcg tttccatccc aatgtatttc
    26881 ccgataccat gattggcatg gacaacgtaa tctcctgctt ttaactcatt atagcttttc
    26941 aatcgctctg cgtttgttac tgtttgacgt ctcgtttgtt ttttcgtcgt tttttggaaa
    27001 atttcttttt ctgtgatagc tactattttt tcttgaggaa gttcaaaacc agcctgcaaa
    27061 gctccttcaa ctaattgtac ctgtcctctg atcaatgcat ttttttctgt ttctactact
    27121 aatatgtctt catctcgaag catttgttct gctttgcgta ttctgtcctt tgtcggaata
    27181 aagatcacaa cagtctgttt ttgcttgcgc caacggtcca tttctgtttt cagcaatggc
    27241 atttgtccga agaactgttg catcgtccga tattgaaaat tatggattgc ttggaaacga
    27301 agatttccca tccctttttg gaagagtgag aaaaaggttg tggtgaactt ttccttctgc
    27361 acgatttttt gtatatctgc tgaaaatgtc tgctcagaaa acacccgcaa ttcgctgatt
    27421 ttttgagtct gccattctgc cgcttccctt tcgatttccc gatttgtttc catgattcgc
    27481 tgataatcat caacgactag taaactattt gaagggaaat aatccaagat cgtcacagat
    27541 tcttggtaaa gaagatctga gtagaatttt gcttcttctg tcgggacacc tgcttgccag
    27601 cttgaagtca gctgaccgaa gtaatcttgc aaaaactcgc ggtctgcttc ttctgtggtc
    27661 gcagcaagcc gtttttctag cattttttgc atttgctcta ttccatgttc tagatcctct
    27721 ggtccgtaga cttgttcact cgttggggaa acccagattt cttccgtttt ttcgattgag
    27781 cgttgtgttt ctgcttcaaa ataccgcata gaatctatct ctacatcaaa tagttctaca
    27841 cgaacaggat aggttgtcgt taacgggtaa atatcgataa tgcttcctcg aatactgaat
    27901 tctcccggtt ttgcgaccat ctcttctcgt acatagccca tcaaagtcaa ttggcgagga
    27961 agattttcca cgtctatctc atcaccaata tgccaattca attgcgcctg tagccaagtt
    28021 ttcttattcg gcagtcgttt gtgcaaagat gcgactggca acaaatagat acctgctttt
    28081 ttttcttgaa gtgcgttaag cgttgcaact ctctcgcctc gcgcttctgg agaagaaaag
    28141 gccatttcag cagaaagcac ttcatccact ggaaataaat ggatctgatc ttgcggaatc
    28201 acatgttgca gatcttctgc taactgattc gcataataca aatttggcat cagaataatc
    28261 atgtttttat ttgttttctt aaacgctcga gcaaatagaa gtgttttcgc tgagcccgct
    28321 aatcctgtga ttagttgtct aggcattttt tcttctaaat tgctgaccca ttcttttact
    28381 tgcggatctt ttccgactaa ttgaataata tccattcctt ttcctccttc ctcaattgaa
    28441 tcgattcatc gcatccacga acgaatgccc ttctatgaga tattcgactg ctttaacaga
    28501 ttgacacatg ctttcttcta tcaaaggctg attttctttg ctgaaaggac taagcacatg
    28561 ctggactact gtttttttcc cttctggcct gccgattccc accttgattc gatcaaagac
    28621 attcgtattc aaatgggaaa taatactttt gataccgtta tgcccgccgg cacttccctt
    28681 ttgacggagc cggatttttc ccactgccag atccaaatca tcgtagatta cgactaattc
    28741 ctctggataa atcccaaaat aagtcattag tgggccgact gcacgaccag attcattcat
    28801 gaatgtttgt ggtttgacta aaaggatctt ttctccatta tgaaaaaatt cggcaacttc
    28861 tgcttcgaac ggattttttt tgaaagtagc ttgatgctcg cgtgcaattt tatccacgac
    28921 cataaagccg atattgtgtt ttgtatattg gtatttggta cctgggtttc ctaacccgac
    28981 gatcattttc atttttgttt tccacctaat tctaaaaagc agcacaaaag gctggactgc
    29041 taattagcgg tccagtccat cgagcttttt tcttttttac acttgtcaat gcatagtata
    29101 acacaaaaca aggcgtttcg gctaaaagag aatcgttaat aaatgataaa gaaattaaaa
    29161 atttcttcaa agtttaatga aataattgat atataaaaat agtgaaataa cgcacatgta
    29221 agcttttaca tataatacaa ccttgttatc tgttatattt tatagccaaa tagcgtgaca
    29281 tggggcttga gaaatgttag cataagcatg ggaaaaaaca aatcaatgga aggattgata
    29341 ctaaatgact gcagctgcag aaaaaaaaga tcatcaaaaa gttattcttg ttggagacgg
    29401 cgccgtaggt tctagctatg cctttgctct agttactcaa aatatcgctc aagaagtagg
    29461 tattgtggat atcaatactg ctaaaactga aggagacgca attgacttgt ctcacgcttt
    29521 ggcatttact tcacctaaaa aaatctattc tgctacttac gcagacgcac atgatgctga
    29581 cttagttgtt attacagctg gcgcaccaca aaaaccaggt gaaactcgtt tagacttagt
    29641 aaacaaaaac ctaaaaatca accgcgatgt tgtcacacaa atcgttgaat caggatttaa
    29701 cggtatcttt ttagttgccg ctaacccagt agatattttg acttactcaa cttggaaatt
    29761 ctcaggtttc cctaaagaac gcgtaatcgg ttcaggtacc tctcttgact cagctcgttt
    29821 ccgtcaagca cttgcggaat tagttgacgt tgatgcacgt aacgtccatg cttacatctt
    29881 aggtgaacac ggagattcag aattcccagt ttggtcacat gcaaatgttg ccggcttgca
    29941 aatctatgaa tgggtaaaaa acaacccaga aatcgatgaa gaagctatgg ttaacctatt
    30001 ctttggcgta cgtgacgctg cttacacaat tatcgagaaa aaaggcgcta ctttctatgg
    30061 tatcgcagta gcattagcac gtatcactcg tgccatctta gatgatgaaa atgctgttct
    30121 tcctttatca gtattcatga atggcgaata tggattgaac gacatctaca ttggtgcacc
    30181 tgctgttatc aaccgtcaag gtatccaaaa agtaatcgaa attcctttaa gtgacagcga
    30241 gcaagaccgt atggctgctt ctgctaagca attaaaagaa attctagatg aagcttttgc
    30301 taaactagac gctgaataat ctttgaacat gacggaaaac atctattcgg tgttttccgt
    30361 ttttttattt tatcaccctt atggtttcta aattttttca taaagtagag ataaccttcg
    30421 tcttttcctc taaattatgc tatcatgaga ccgttccacc ctaaactttt acttaaggag
    30481 ttgtcgatat gacaagatct tcgcatcgaa aaaaatcgaa acatgttgct ttgctttcag
    30541 ttcttggtgt tctcttagtg ctgatcagct tttataccta tcgcagtaca tactacacaa
    30601 agcatttttt gccgaataca gaaataaatg gaataaatgt cagcaatcta acagtcgaaa
    30661 aagcaaatga aaaattaaaa gaagcttatt ctgataaaaa actggctatt aaagaagatg
    30721 gaaaagtctg gcaggaagta ccaaaatccg agctcggcta caaagatgat ttcacttcgg
    30781 agctttctcc gatcctaaat gaacaaaacg gatggacttg gggaatgact tatgtctcag
    30841 cggcagaaaa acaagaaata gatcctgtca gtcaaaacca ccaaaaacta gacactaccg
    30901 ttcagacatt gacaactaag ctgactgatt tgaacaaaga ccggacacct actactgatg
    30961 caacgatcga aaaagcaggt gactctttcg ttatcaagcc tgaagtcaat ggaaatacga
    31021 tcgacgtcga tgctgcggtc aaacaattaa aaagtgcggt aaactctggt aaagatacaa
    31081 ttgaattgac tgaattcaaa gaaaaaccaa aagtaacatc tgaagacagc tcactgaaag
    31141 aacaactcgc atccatgaat gctatcgcaa atgtaaaagc tacttacagt ataaacggtg
    31201 agactttcca gatcccatca agtgatatta tgagttggct gacctacaat gatggaaaag
    31261 tcgatttaga tacagaacaa gtacgtcaat atgtaacaga tttaggcaca aagtataaca
    31321 caagtacgaa tgacacaaaa tttaaaagta caaaaagagg agaagttacg gtcccagttg
    31381 gcacttacag ttggacgatc caaacagaca gtgagacaga agcattgaaa aaagcgattc
    31441 tggcaggcca agattttact cgttcaccca ttgtgcaagg tggcacaacc gctgatcatc
    31501 cattgatcga agatacgtat atcgaagttg atctggagaa ccagcatatg tggtattaca
    31561 aagacggaaa agtggccctt gaaacagata tcgtttccgg aaagccaact acacctacac
    31621 ctgctggagt cttctatgtt tggaataaag aagaagatgc aactttaaaa ggaacaaatg
    31681 acgatggaac accttacgag agtccggtaa actactggat gccgattgac tggacaggtg
    31741 ttggtatcca cgattcagac tggcaacctg aatacggtgg agacttatgg aaaacccgcg
    31801 gttcacacgg ctgcatcaac accccaccaa gtgtaatgaa ggaattattc gggatggtcg
    31861 aaaaaggaac gcctgtattg gtcttctaac aaaaataata tataaaaaga aagcacccgt
    31921 acgattggta caggtgcttt ctttttatta tctaacaatg tgctacttac atttcagcag
    31981 cagtaaagac ttctgaaaca tcatcatcgt cttctagctt atctactaga cgttccaatt
    32041 gctctttttg ttcctcattt aaatcaatcg tcgtttgtgg aatcatcgtc aattctgctt
    32101 gcgccaaagt gaactctttt tccaactcat ctcgtacagc agcaaaatct tctggtgcag
    32161 tataaatctc gaatacttca ggagaagttt gcagatcttc tgcccccgcc tctaatacat
    32221 cctcaaacat cgtctcttca tcaacagtca acccatcgcg ttcaatagcg atatatcctt
    32281 tgcggtcaaa caagtaactg actgaacccg tttctcccag tgatccaccg tttcgagtaa
    32341 aagctactcg gacatttgtc gctgtccgat tacggttatc tgtcaatgca tggactaaga
    32401 ttcctactcc acccggacca tatccttcat acgtgatttc atcgtaattc gtttcatcta
    32461 cggcactcgt agccttttta atcgcccgtt ccacattgtc gttaggcata tttgcagctt
    32521 ttgctttgtc cacaacaagc cgcaaagctg gattcataga tggatcagga ccgcctgctt
    32581 tagctgccat ataaatttca cgagaaagtt tctgaaagac tttccctcgt tttgcatctt
    32641 gggcattttt tcttccttgg atattatgcc atttactatg tcctgacatg atttttcctc
    32701 ccttgttctt ttgagaatac acttctattc tagtactatt tcacaaaaaa acaaagccac
    32761 agccaatcta taaacgcttc ttgaatgccg caaaaagcac acataatatc acagcagtca
    32821 gagcaccgat cgaatccaac atgacatctt ggaacatagg tgttcgtcca ccggtcatca
    32881 tctgatggaa ttcgtccaaa cctgcgtacc ctgttgctga aagccaagca aggatcgctg
    32941 tcagccacca aatttttagc ttggggaaaa cacctaaaaa caagctgcct cccaaaataa
    33001 aataggtacc gaaatgtgcg cccttcctta aaaagaactc taaaaatttg gcgtagccca
    33061 gatggttgat actcaccata cttccaccat aattaaaacg tatacccgct aatgtgtctt
    33121 taaatggctg attaggcagc cagctttcta atcgcgaaac ttgtgattgc tgtccgtaag
    33181 tttgagaaga actgtaaaat aagattataa cgactatcag tgcgattact aaataaatat
    33241 ttccgttttt catttgtttt tttgaagaat tcataagtca cctctgtatt ttatcttaga
    33301 ctttttttga agaaacaaca atcattttca tagagacttc ttccataaaa aagtgctata
    33361 cttaattttg tattacaata tgaagggagt tttttcatga gttattcatt aaattggaat
    33421 ctagattcta ttttttccgg aggcagtcat tctgatgctt tgaaccaacg gatgaagcaa
    33481 ttggaagacc aaatgaacga gtattatcac cgcgtaacaa aatggtcacc tagttctgac
    33541 aatgcagagc agttaaacgc tattcttcaa ttgcaagaaa cgattacgaa tggttttacc
    33601 caatgcagca gctatattac tgcattgctt tctgccaatg tcaatgattc agatgcaaag
    33661 gtcttatcag gcaagcttta cgcaatgctg cctcgtctgc aatcagccga aactgtattg
    33721 tcaaagaaat ttgcagaaat atctgacaat gattggaatc agatgctttc tcaatcttcg
    33781 tttgaaacaa ttgcttttcg tttaaacgag attcgtcgtg atggctcaca attattatca
    33841 gaagctgaag aaaacattat aaatacgctt tctttagatg gtctaaatgc ttggagcagt
    33901 cattatgata cgattgtagc cagcatttcg attcccttcg aacaagatgg acaagtagtc
    33961 gaattatctg ctggacaagc cttcaataag atgatgggcg atccagatcc aaaagtcaga
    34021 gaaacacttt tcgcagcatg ggaagaagcc tggaaagaaa aggcacccct cttcacggat
    34081 actttgaatc atttagatgg ttttagactt tctgactatg aacttcatgg tgtcacagat
    34141 tttctacaaa aaccattaga gtacaatcgg ttgaagaaag aaacattgtc tgtcatgtgg
    34201 gatacaatcc agaaaaacaa acaacccctt gttaattact tgactagaaa agctaatctt
    34261 ttcggtaaag aaaaaatgga atggcaagat caagatgcac ctattatttt aggcgatttg
    34321 aaagaaaaaa cctttagttt tgacgaagca gcagcattta ttatcgaaaa ctttaacaaa
    34381 ttcagtccaa aaatggctaa atttgcccaa tctgcttttg aaaagagctg gatcgaagca
    34441 gaagatcgtc ctgggaaacg tcctggtggt tattgtactg agttaccaga aacaaaagaa
    34501 tcaaggatct ttatgaccta cagtaattct gttaatgagg ttgcgacact tgctcatgaa
    34561 ctaggacatg ctttccatag cagcacgatg tgggatttac cttctttaaa tcgcgaatat
    34621 gccatgaatg tcgcagaaac agcaagtaca ttcgcagaac tgatcgtagc cgatgctaca
    34681 ttaaaagtcg caaaaacaaa agaagaaaaa atcaatttgc tagatacaaa actgcaaaat
    34741 gctttagcta tgttcatgaa tatccattcc cgattcattt ttgaaaatcg attctatgaa
    34801 gcacggcaag aaggattagt ctcagaagat aagatcacag agatgatggt tgaggcgcaa
    34861 aaagaaggct atcaaggagc tttagctact taccatccat atttctgggc tgcaaaattg
    34921 catttcttta ttgatgacgt accgttttat aacttcccat acacatttgg ctacctcttt
    34981 agtttgggca tctatgctta cgccaaccaa aagggagcaa attttgaaga agaatatatc
    35041 catttactac gcgatactgc ctcaatgacg acggaagatc ttgcgaagaa acatttgaat
    35101 gtcgatctta cccaaccaga tttttggcaa gcaggtatcg acatggtgac tgaagatatc
    35161 caaacgttca tggaattgac agaagaattt atctgatttc tattttatca caataaaaaa
    35221 agagttagtc cagaatgggc taactctttt tgattaatca ttcttacatg ctgacagcaa
    35281 agtcaggggc aaaccattga actgaaccaa cttttacgct ttcgcctggt tgaggagcat
    35341 ggatatattg tcctccgcct aaagcaatcg ctacgtggta agttccgcct tgtgaccccc
    35401 agaataacaa gtctccagct tttgcttgag aaactgaaat ttttgttcca gctgattctt
    35461 gaggaactgt ccaaccaccg atgtcacgac cagttacttg catgtaaaca tagcgtgtga
    35521 accctgagca gtcaaagcca cttggatctt taccgcccca aacatatgga gtaccaatat
    35581 atttgtaagc ttctgctacg attgctgcac cattcacact tccagaagga gctggagcag
    35641 gtgttacagg ttttggttgt tcaggtgttg gtgttggcgt tggagccgga gtactacttc
    35701 ctgtgccgtt tcctgtatca acactttgat ctgttgatgg tgttgtaggc gcaggtgttg
    35761 ttgattcttc tgttgttgaa gattcaggca ctgttgttga ttcttctgtt gctgaagatt
    35821 caggcactgt tgttgattct tctgttgctg aagattcagg cgctgttgtt gattcttctg
    35881 ttgctgaaga ttcaggcgct gttgattctt ctgttgaaga ttcaggtgtt gttgattctt
    35941 ctgttgctga agattgtgta gctgatgatg attcttcagt cattgaagat tgtgtagctg
    36001 atgattcttc tgttgctgag ctttgtgcag tagatgaagc ttgagtagct tgtgcttcag
    36061 cctctgcttg ttcgcgtgct tctttttcag ctttttcttg tgcagcttgt tgacgagctt
    36121 gttctgctag acgttgttgt tcacgaatac gagcttgctc tgcttcagct tctgcttttt
    36181 gacggttcaa gtcagctttc ttgtcttcag cagttgcttg ttcagcagct aatgaagttt
    36241 tcagtacgtt caaatcagct tgtttagata aaagatcgcc tttttgagat tccaaagcag
    36301 cttggttttc agctaattct tttagtttag catcgttttc agcttttttg tcttctacag
    36361 cttttttatc ttgtttttgt tgttccatca agtcgttgtt tgcttttacc atcgttgtca
    36421 ttgcttgaac gcgtccaata gcatctgcta atgaatcagc attcaataca gcatcgatgt
    36481 agtttgagct tgtgttgctt acttgtgctt cgcgtgcttg tttttggatt gtatcttcac
    36541 gtttttcaat acgttcttgt aaatctgcaa tgtcttttac taattgtgca gattcttgac
    36601 gcaatgtatc ttgttttgct aataggtctt gtgcttgtgt gttgatttca gaaacttggc
    36661 tttctaaggc atcgatttgt gattgtgcat ctgcttgttg atttttcaag tctgcaatct
    36721 tttgatcttg ctgttgtatc tgagaatcaa aatcgtccgc cgcggcagcg atcggtgatg
    36781 ctacggcagt caaggtcatt gaacatacca ttactgctga tattaaactc tttttcactc
    36841 ttcattcctc cgactggctt aatttaataa atatctaaat atatttaagt ctttcttaac
    36901 gatataaaaa ttgtaccata gcagtgtgtc aacgatataa tagttatgtt acaaaaatgt
    36961 ttcaaaacaa cttttaaaaa tgacaaaact gttcgtttca gaaaatgatc atgaaaaagc
    37021 cgcgttaagt ctagcatttc ttaagataac aacgattctt tttcgctttc gacctaaaaa
    37081 taaaaaaaga aattattcat cactgaataa tttcttaaag ggaaaaatga ataatacaaa
    37141 tataatcatg ttcaacagca gtgtaggtcc taaaaacctt gtaataaaat acgtgttatt
    37201 tactactgct aatttaaaaa tcaactggac caccatcgta aacaattcat aacccgtgac
    37261 aaagatgatc atactgaaaa attcagtaaa gatgttgaca tggataacgt ctttcattac
    37321 atacatcaac catacaatta aagggagagc tactgcatag ataccgataa cgccaatata
    37381 gtaagcgtca tagatagccc cgagaacaat cgtggtaatc agtaaataac gtttttcaaa
    37441 cgccatactg caacataata atgccaatat cagaaagtgg gcatttgaca tataggtgcc
    37501 tttcgaccac tcccctagca ttcttgttaa atgaccatct atcaacatca aaaagaacaa
    37561 aacgattggc agatagtact tcattgtttc tttcttcaac atggactaat cctccgctag
    37621 ccgttggaca atcgtcacaa ctgacacgtc atacatttct gcataaggtt tcacataaac
    37681 ttcccgatcc agcccataac tatctggttt cgttttaata accgtaccga tcggcaagtt
    37741 agctggagaa ttccctccaa gaccggatgt ctggacaaca tccccttctt tgatatccgt
    37801 atcaccagtt aattgggtca ccactaaggc atggagcttt tcatcatagt ttttaagcaa
    37861 accaaacgct tcgccattag ccgaagatac ccgtactgga aaatgattgg agctttcatt
    37921 agaggatgac agtaattcga ttttagacga agccgtattg acctcgatca ctcggccaat
    37981 caatcctttt tgcgacatga ctgccatatt tgcttcgata ccgtctttag aacccttgtc
    38041 tacgatcagc atgtcctgcc aactgtcagg cgaacgagta atgacatttg ccgttacttt
    38101 ttcgtaacta gtcagcgtct gattcaactc aagttctttt ttcaacgctt cgatttctct
    38161 ctcgtaattc ttgttttgct gtgaaacgtc atcatagcta tcgatttttt cttttagccg
    38221 ctcattttcg gcataagttg aaaaaagatt atggacagaa tctactccat ttcgtaccca
    38281 ccgtactggg gcagagattg ttttatcaac cattgcaaca ctgtcattaa cgatggattg
    38341 gaagaaattg ggctttcctt cattcgctcg ctgcgcagcg gtcacactta gtatcgtcac
    38401 cacgatgata acaataacca aggtaataat aatattttta ttaggattga acttcttcac
    38461 aaagacacct cgaattaatt agactcttgt gttcaatttt atcactaaat gccgtgaaac
    38521 aaaaggtaag ttgctcctct taagcttttt tttagcaaat aatagattct gtcattttta
    38581 gcctgaaaga caaatttttt tatttgttta tggatcaatc tttgctttga ataactgcaa
    38641 tcataccatc tgaaaaagaa aattctgcgg tatctgaaag aaattcgtta cttgcataag
    38701 atgtcggata ttctacttct ttattttcca atacatactt gctgcctttt aatgtaagat
    38761 tcgagacggg agtcaagcag caataagcta aatacttcat atctggtatc tgtcttacta
    38821 tatgctctcc aggcaaataa taagacaaat aattttgaca atctctgata ataagctgat
    38881 gggcaaaggg tttgaagcga ggttccatac ctaaccagag attggctaaa agatgatcca
    38941 atcttccgcc cgtagctcca atcaaagtga cttccgcttg cgggtaacgt tcaaatgttt
    39001 ttaagatacc taactgtgta tctgtatcgt ctttttctgc aggggaacgg gtatactctt
    39061 tggcttttgc aaatacttcc ttctgctctt cgttcgacaa tgaatcaaaa tcacccactg
    39121 ccagatctac tgggtagcct gcttgaagca ggtacagcgc accacggtct atcccgacat
    39181 aggcatcgta tttggacagc agagactgcg gccagttttg cggattacct ccagcagcta
    39241 ataaaatttt catttagtct aatgcctctt ttaatcgttc gatttgtccg actggatttt
    39301 cggctccata gatatatgat cctgcaacga agacatccgc ccctgcatct ttacagattt
    39361 ttgctgtttc tggaacgatt ccgccatcta cttcgattgc ataagtccaa ttgttctctc
    39421 tacgtagatc agcgagttcc gtaatttttt ctactgtttc ttcaataaag ctttgtccgc
    39481 cgaacccagg attgacagtc atgactagta cttgatcagc caaaggcaaa acatgtttga
    39541 tcatggagac tggtgttcct ggattgataa ctactccagc tttaactcct aagctttttg
    39601 tcatttgaag tgcccgatga atatgaggag ttgcttcgac gtggacagta atgatatctg
    39661 ctccagcttt tgcaaatgct ggaatgtagt tttctggatc aacgatcatc agatggacgt
    39721 ctaacggtaa tttagtaaca ggacggattg cctgaacaat atttggccct aatgtgatat
    39781 ttgggacaaa tcggccatcc attacatcta cgtggatgta atctgcgcct cctttttcca
    39841 ctaactcaat gtctctttgt aaattggcaa aatctgcact caaaatggat ggtgctatct
    39901 tcattcttgt ttcctcctat tttcgtttac cttctttttt tgcatacatt ggttttcttt
    39961 tttcgatttc ttgtaagaat tgcaaataat tgtcgtaacg tgtctgtgcg ataccacctg
    40021 tttctactct atgttttact tcgcagccag gttctttagc atgcatgcac tctctaaatt
    40081 tgcaatggac agaagcttct acaaattcag gaaattgtct cggcagttct cctgcttcaa
    40141 ttgtcaaaaa gtcaatcgag ctaaatcctg gtgtatctgc tactaacccg ccatagatag
    40201 gaatcagttc cacatgacgt gttgtatgcc gtcctcttcc aagtgcatca gaaatctctc
    40261 ctgttgctaa attcagttcc ggtgatattt gattcagtag cgtcgatttt cctgctccag
    40321 actgacccat aaagaccgat agccgttctg ggaagtaacg gatcagttct gtcgtatcac
    40381 ccgtatgatt gggtacaatc accggatagc ctattttagt ataggtttgc ttgatctctt
    40441 cgattttttc tgggtcgtct gacaagtcgg tctttgtcaa aaaaataatc ggttcgatcg
    40501 actcgtattc caaggtaact agaaagcggt caagtagatt ataagaaaat gcaggctcta
    40561 cgatacttgt gacaatgatt ccaagatcaa catttgtgac tggtgggcga actaattgat
    40621 tttttctcgg caagatttcc agaagatagc cgtctgtttg attttcactc tcaaagatca
    40681 cctgatctcc gacaagcggc gtgattttcc gattccggaa atttcctctt cctcttgttt
    40741 gataggtctc tccgtttgcg tatacatagt aaaaaccgct gattgctttt ctgatttgtc
    40801 ctttgataag tgccacctcc gtttttgttt attttaccat acgaagagga aagtaggtgt
    40861 tattccatgc aaacttctca aagtatatgg cttgaaaatt gatcaaaaga gatagaaaca
    40921 caaaaaagag aatgcaacaa atcaatgtcg cattcccttc tgatatattt tattcagcac
    40981 ttattttgaa ctttctgagg tgctagctga tgaacttgtg gagctggaag attcttcttt
    41041 tgaagagttg cttgtgctac tggagctact tgagctgcta gaactgtctg aagagtcttt
    41101 ttcagaacta gaagacgctg gatctggtcc tttagagtaa attacgttca caaccattcc
    41161 tttggtaatt gtcgttcctg cccctggtac tgtacgaatc actttatctt tatccaccgt
    41221 gtttgaatat tcggaagtct catgcccgat atattctgca ccgacactag ctaaataact
    41281 ttgtgcttcg ctttttgtat agccggagat atcattcaat ttaggctctg ttccttggct
    41341 tacgacaaaa ttgatgtaag tttcttctgc tacaacttca cccgaggctg gatcctgact
    41401 gatgatcgaa cctgatggta cagtgtcgct atagtcataa gtagcactaa tattattgat
    41461 attgaatcct tgtgtaacaa gccaattacg aacagtttcg tagttttctc ctacatgact
    41521 actcaaagtc actgtttctg gtcctttgct gactgtgaaa gtaatcgtgt ctgttttagg
    41581 atcgacttct gtatcttctg atggagattg cgaaatgatc attccgcttt ctacctctga
    41641 actgaattcc tcttcttttt gaatcaagtc agcagaaaac cctaattctt tcaaacttgc
    41701 ttcggcatct tcataacttt taccactgta atcatctaat ttgatttttt tcgtgccgct
    41761 actaatatac agagtgactt cgcgtttttg cttgactgtc gttcccgctg ccgggtctgt
    41821 cttcactaca ttaccttctt cgattttgtc atctgcaatt tcttctgttt ttgttgctac
    41881 ttctaatttc gcttttgcga gtgtttctct agcagaagct tcagaaagat cagaaacatc
    41941 aggaacaaca acttctcctc gcccgccaga agcaaagaat acagctgttc cgattcctaa
    42001 aacagcaaga atagctaata ggatcagcca ccattttttc tgtcctttct ttttaggatc
    42061 aggcagaact tcttcctcct ctggtaaggt ttcgttttct ggcttgtctt ttggcagagg
    42121 catagatttg aatgaatcag gcattggtgc atcttccgta aggggtgtga taacttttgt
    42181 ttcattatcc atcacatgag gctgccattt ttcttcgttt gcacgagctg gtgataatac
    42241 tgtagaaaga tcatcagaca tttcctcggc tgacttataa cggtctgcag gttctttagc
    42301 cgttgcccgt aaaatcacgt tttccagtgc ttgtggcaca tttggatcaa gtgcttttat
    42361 agatggaaga tcatcttgaa aatgttttaa agcaattgtt acagcagatt caccatcaaa
    42421 cggtacgcta cccgtcaaca tctcataaag gatgatccct aaagcataaa tatctgactg
    42481 cttcgttgcc atacttcctc tggcctgctc aggggacaga taatgaacag atcctagcat
    42541 cgtattcgtc tgcgtgatcg atgtttcaga taaagcgata gcaatcccga aatccgtgat
    42601 ttttacaaca ccttcattat cgatcagtac gttttggggt ttcaaatctc ggtggatgat
    42661 ttgatggtta tgagctaaag aaatagcaga aaggatctgc tgcataatat ttactgctgt
    42721 ttcataagga acaggataat gtgtttggat atatcgtttc aagtccattc ctttgacgta
    42781 ttccatcacc agatactgca tgttgtcttc ttcaccaaca tcgtaaacac taacaatgtt
    42841 tggatgaacg agttctgttg ctgctaaagc ttctctctga aatcgtcgaa tcgcagtctg
    42901 gtcattttga aagtcaaatc gtaagacttt aactgctaca tcacgatcca agattaaatc
    42961 gtgcgccaaa aatacatttg ccataccacc gctaccgata tttccagtga tttgataacg
    43021 gccatttaat tttttgccca actcgatcat acactgtcct ccttatattc gataagaaga
    43081 acggtgatat tatccgctcc gcctgcttca ttggcacgat caatcagctc agttacttta
    43141 tgagacaatg ggccttcttg attgatgatc gttcctattt cttcttcaga cagcatgttc
    43201 gtcaagccat ctgaacataa cagcagtcga tcttttagtt gccaaagatg agtagaaaca
    43261 tctacttcga ctgttccagg catgccgaca gaacgtgtta aaatattttt ccttggatgg
    43321 ttcactgcca tttcttcgct gatttctcct gatttgacta gttcattgac taaagaatga
    43381 tcctccgtca attgcatgat tttatcttca cgaatcaaat aagctctgct atccccaaca
    43441 ttggcaatcg tgaaccagtc atctgacaga gcggccgcta cgattgttgt tcccataccg
    43501 ttatattccg gctgttcttg tccacgctga taaatcagca tattttcttc ttgaatcgat
    43561 tgaatgaacc attgggcgat tttttcatcg tcaacagctt cttgtttttc ccaagcttcg
    43621 cctagattcg ttaccgccat ctgactggca atgtctccgg cacgatgacc acccatcccg
    43681 tctgctaata cagcaagctt gagacctgaa cggctggtaa atacactggc atagtcttga
    43741 tttgtgttac gtcgtcttcc tacatctgat tgatattcaa tctgcatttt ttcacctcat
    43801 tactttttgc gcaaacaaca aatgaaaaat ccatctgtgt aaaactgatg cggatacaaa
    43861 gtcaacattt tctcttcgat tgatgattgt agcataggat tggtcaaaac atcaatcctc
    43921 tcaaaatcag ggtgtctttc caagaaagca gaaacaacgt cttggttttc ttcttttaag
    43981 atcgtacaag tgctataagt cagaataccg gaagacttta aagttggtgc gcagctttct
    44041 aaaatttcca attggatttt tggtaaattc gctaattcat ccggctgttt tttataacga
    44101 atatctggtt ttcgccgaag cagcccaaga cctgaacaag gcgcgtctac taaaatccga
    44161 tcaaactgct ctgcttcgaa ctgtttactg acttctctag catccatctt ttgagcgtag
    44221 acagcagaag agacacctag acgtgctgca ttatcttcaa tgagtttgac tttgtgttcg
    44281 tgtacatcta aagcgaccac ttctccaccg catgacggat ctaaaaaaga agcaatatgc
    44341 gtcgtcttac ctccgggtgc tgcacaggca tctaagacat gatgttcagg ctcgatttgc
    44401 atagacggcg ctacaagcat cgaactttca tcttggatcg tcatgacgcc atcgtggaac
    44461 aatgagctag aagctaaatg cccttttttc gctactatac cgtatggact gacttggctt
    44521 ttttcagctg tgatctcttc ttcttgcaaa acagtgatgg cctgatctct ggaaagtcgg
    44581 cgtgtatcta ctcgggcact agcatggcta ggctgatata gcgataaacc gagcttttca
    44641 gtttcttcgt atccgatttg atccaccagt cgtttcgtca tccatagagg caggctgatt
    44701 ttgacagaaa gtctttcgat aggatcagca atgccttgca gatctggtgc tccttgacgc
    44761 tgataattcc tcaagacacc atttacaaat ttccctgtcc caggatttcc ttttactttt
    44821 gcgatttcga ccgcctcgtt taaaatagca tgtgcaggga ctttatctaa aaattctaat
    44881 tggtatacag aaagataaag aagcatcttg acccagtcat ccactttttt tgctttagcg
    44941 atcaatggtg caacgtaaaa ttccaatagt cgctgatggc taatcgtacc atagatcaat
    45001 tctgtaaata aacccacatc tttttgattt agctcgcttt gtttgatcat ctcattcaac
    45061 aaaagattcg agtaggcgcc acccttgttc actcgctcta atgtcagtaa tgccatatat
    45121 cgtactgatt ttttcatttt tttagggatt tttttcatta tttcacctgc tgaccaatct
    45181 gaacttgctg accgcttccg ttaaggaaat catgtacggc ctgttttcct ttaccagctg
    45241 gctgtaattc attgatggct aagacggtct gtttaccgca agcaatccat agattttttt
    45301 tgtctttccg gatgatcgta ccaggtgctt tgtctgtagt ttctgccaat acttcaaccg
    45361 ataataattt ccagcgtatg ccctcatagg tcgtgaatgc aattggccaa ggacgcattc
    45421 cgcgtacttg gttgtcaatt tcttctgcag ttttatgcca atcgattgct tcttgttccc
    45481 gtgtgatgtt tggcgaaaaa gttgcttctg actcgtcttg aggtactggt ttttgtccat
    45541 ccaaaatatt gggcaatgtt tctagcaata gctttcttcc taaaaggcta agcttttcaa
    45601 acatcgtccc tacatcatct tgtttagtga ttggtatgct ttcttgcgca tagattccgc
    45661 ctgcatccat ttttttgatc atttccatga tcgttacacc agtttctttc tccccattca
    45721 tgatggcata atgaacaggc gcacctcccc gatatttagg aagtaaagaa gcatggacat
    45781 tgattgcccc taattttggt acttgcaata acttttcagg caagaattgg ccaaatgccg
    45841 cagtgacgat cacatcaggc accaattcaa tgatttcttc catttctggc gaaccggaga
    45901 ttttctctgg ctgcagcaca cggataccgt gcttcagagc cgcttttttt accggtgtcg
    45961 gcgtaattac tcgtttccgc ccaactggac ggtcgggctg tgttaccact gcctggatct
    46021 cgtaacctga ttctatcagc ccttcaagaa tcggcacaga aaaagcaggt gtgcccataa
    46081 atactagctt agtcatcaag atgttcctcc atatattctt caagttcttc ttccgggatc
    46141 tgctgtatca ttttctcaat gaacaagata ccgtctaagt gatcgatttc atgctggaag
    46201 gcacgggcta aatagccaaa agccgtcact tctatctctt ctccgtctcg atcataataa
    46261 cgcacggtca cttcatctgc tcgcttgacc gttccataga catgcggaat actgagacaa
    46321 ccttctacgt caaggctttc accttttgct tcgatgattt ctgggttaat cagttcaaat
    46381 ttctcgcctt catctacttc gatcacagca attctcttgt tttgtcctac ttgaggagca
    46441 gcgatcccta ttccgtcatt cgcaatcatt gtctcatata aattgtctaa taaagcgatt
    46501 gtctcgtccg tgattacatc gattggctga gcagttcttt ttaatttatc attagggtgg
    46561 atcaatatag gatagcgcat aatttggccc tttcttaaat aaagtttaat ggttcgttgt
    46621 caattgccac aaaaagacct tgtcgctgtt ctttctggct tccattcaaa atttcatcca
    46681 aaacatgagg aagattcggt tcatgtttat atttgatgat tagttgataa taatatcggt
    46741 ttttcactct caaaatcatg ctgggcgttg gccctaatag caagctttga gggcttaaca
    46801 cttcttttag ctgattggca atctgaaaga ttttctttgc cgctacttgt tcttcaggat
    46861 ggctggcggt tattttcaca gtaaagtaat aaggaggata gcctccacga tgccgtacat
    46921 gcatttcctg ctgataaaac tgctcataat tttgtttttt agccaattct atggcgtaat
    46981 gttgaggatt gaatgtttgg atcacgactt cgcctgcttt ttccgctcgc cctgctcgtc
    47041 ctgaaacttg ggtaagcaat tggaatgtat gctcactaga acgaaaatcc ggtaaattca
    47101 gggaggtatc agcattcaac accccaacta atgtcacttc tggaaagtcc aaacctttag
    47161 caatcatttg tgtccctaat aatatatctg cttcttttgc accgaatttt tgtaaaatct
    47221 gttcgtgtgc cccttttctt cgagtggtat ctacatccat acgcaaaatc ctagcttgcg
    47281 gataaagttc tcggagttcc tcttctactt tttgagtacc tgttccatag tagcggattt
    47341 tattgccgcc acaattagga cagcgattgg gaataggttc ttcatgtccg caataatggc
    47401 agcgcattga acgtgtatcc atatgcagtg taagagagat atcgcaatta ggacatggaa
    47461 gaacaaatcc acagtcccta cacatcacaa aagacgaata tcctcgacga ttgagcagta
    47521 ggacagtttg ttcttttttg tctaatcgat tttgtatttt ttcctgcaaa ttagcagaaa
    47581 aagtagaggt ccgatgattc tgaaactctt cacgcatatc tacgatctca atagctggaa
    47641 gctgtgcagc tgctttggct cggtggttta actgcaataa ctgataaacg cctttttgag
    47701 ctcgtgctct tgattctaaa gagggcgtcg cgcttcctag aactattggg caatgatgat
    47761 atttactgcg ccaaattgct agatctctcg catgataacg cggtgtctca tcttgtttgt
    47821 aacttgattc atgttcttca tcgataatga tcagcccgat atttttcagc ggggcaaaaa
    47881 tagcagatcg tgcgcctact actacttgcg cttcttcccg ctcaatcttg cgccattcat
    47941 catatttttc accttgggaa agtccgctat gtaagaccgc aactgattct ccgaagcgtc
    48001 ctttgaatcg ctcgaccatt tgcggagtca atgcgatttc aggcactaac ataatagccg
    48061 ttttattttc tgacaaaaca tcagcgattg cctgaagata tacttctgtt ttcccgctgc
    48121 cagtgattcc ctccagcaaa aagacctgat ctttttgctg ctgacctgct gtgatgattt
    48181 gttcgacagc atttttttgt tctgcattca gttccaatgc cgtcgtttgg tcaaatactc
    48241 ggtctttata agggtcgcga taacgttctg attctataaa ctccagccag cccttttctt
    48301 ttccttgatt caagacagca gtactgattc ctttattttt gaaataagca attggttctt
    48361 cttggctcag ttcagataaa cacaaaagaa gttctttttg tttcttggca ttttgccgta
    48421 attttgccca ttcttcttcg atttgctttt cagttaacaa agaacggacc aaacgaatcg
    48481 tttttacttt atttcgtgta tggacttcat atttgatatc tactaattgc tcttggcgcc
    48541 agcgaatcaa ttgagaaagg ctgccttctt cttctgcttc cttccaggaa atcacttctc
    48601 gctgatcaaa caatacctga acttctggtg tgtctgccaa aggatagatc aatttatcat
    48661 attctgcttt catcacactc ggaagcatcg tttgtagaca agtgattttg aatgcgtaag
    48721 taattttttt catataatca gctaatgaaa gtaattcttc attgaccacc ggagcaaggt
    48781 ctagcaaacg aataactgcc ttcaaagatg gattagctga ttcttctgat ttttggatag
    48841 ccataacaaa tccttggaca tgacgattgc cattaccaaa agggacttct actcgcatcc
    48901 cgacttgcaa agctgtttcc atttcagagg gaaccaaata agtgaatggc tgatcggtct
    48961 gcatagtagg tacgtccaca atgacttcag ctgttaatgt catggttcgt ttcctccttt
    49021 ttttgtcttt tcttatcaag cgacaaaaag ttccttgcct attttactag agatcgatgg
    49081 atttgtctta tcttctgcca aatcctaaca aaaaattaac agcagataag aaaaaaaaga
    49141 actgtgtcaa aaagttcaga cacagccttt tctaccagac aataagtggc gaatgtttga
    49201 aaaggaaaca gctgggtttg cttttctttt tagatgttcg ctctattttt ctttattaca
    49261 ttttttgctc ttcacggata cgtgattcca attcgtgttg ttcacgctct ttttgtgctt
    49321 gacgttcctc ttcttccatc ttcaaacgtt cacgttttaa ttcaggatgt ggatcattga
    49381 ctacatttcc tgcatcgatt tcttctaaag cttgaccgac gctttttact gaatcaaaag
    49441 aatctagagt aggctgtgca cttgcatcca attcatgcgc gcgtttactt gctaaaatca
    49501 ctagagaata ttttgaattt acacgatcta atagtgagtc aattgaaggt tttaacatca
    49561 taagactaca tctcctttaa cattttaata tatttaccga ttacgcgatc tactcgaaaa
    49621 tgttcactgg caataatgtt tttgattcgt tcaactgcta gcggcacttc atcatttaca
    49681 acagcatagt cgtaaagagc catcatttcg atttcttctt ttgcaacttt cattcgtttt
    49741 tcgattactt catctgcatc tgttcctcgg cctacgatcc gtgattttaa ttccgctaaa
    49801 tctggcggag tcaaaaagat gaatacacca tcgggcactt tttctttgac ttgttttgct
    49861 ccttggactt caatctccaa gaaaacatct tttccttcat ccaatgtctt gttgacatat
    49921 gacaaaggag ttccataata attcccgaca tattctgcgt attccagcat ctctccagct
    49981 tcgatcattg attcaaactc ttctttgctt cggaagaaat aatcaacgcc ttcgacctcc
    50041 ccttcacgca ttttacgggt agtcattgag atcgaatact gaaaatcatt atcctcactc
    50101 tcaaaaattg cttttcgtac tgtgcctttt cctacaccgg atggaccaga caacacgatt
    50161 aataatccac gctctgacat gacgacgtcc tttcaactag tctttttgta cttatcgttt
    50221 attttgcact ttttttctgc aactttcaag gttatcttta attatagcta gaaattggta
    50281 aaaaagctac cctgtaccaa gaggtcgtaa aaaagctgtc ctgcatcaag taataagaac
    50341 agccaaacat aaacagcttc tcatgttttt cgtttggttg gggttattat cgcagatgca
    50401 agcttttgaa cgccgtgtat aagaggtcgt gaagaagccg attagtttcg agtatgaaga
    50461 aaaattttgt gaaaatagtt tctcacattt ttgcataaat ttggcttaat accgagaaaa
    50521 tggtttttga acatcactta ttcaaaataa aaaaagattg tgacacgaat tttgtcacaa
    50581 cctttaaatg tattcctaga gcaaagaagc taagcgaaga aatccaattc tgtttattta
    50641 ttgtatttct ttgttcagca tccttgctaa aagcccatat tggacaaagt attcactaca
    50701 cccatgatct catcttttcg agaacgtgct ttttctgtcg gatcttctac ctcttctgtg
    50761 tcaattcgaa caataaattt ccgattcatc gtcacgtaag caccgtcgtt gatcaaaata
    50821 aacagttcgt tctcattata gtctgcacag gcatctttcc atacgtcaaa gccgtttttt
    50881 tcagaaggga tatcccgttt aaccacagtt tttccactta attcgtggaa cgttacgtca
    50941 taatatttca ttatctctac ctctttcgtc attcaatatt ttgtacttgt tctctgattt
    51001 tttctaagat cgtcttagac tggacgactt gatttttaat ttcgattgca tttgatttgg
    51061 aaccgatcgt gttgatttcc cgattcattt cttggatcag gaaatctaat tcccgaccta
    51121 caggacattg tgcttcgata agttcatcta gtttttgtac atggatcgcc agacgatcca
    51181 gttcctcgtg aatatctccg cgttccaaca agatggctag ctccgtcaac aaccgttgct
    51241 catcgacttt cgctccaaga aattcctcca gctttttttg ataccttatt tgaaattcct
    51301 tttcatagat ttctacaaaa ctatcgagtt tttttagtac ttctttgaat tcttcagtat
    51361 tctttttcaa cactaaagct aaagcttgac cttctttttc tcgactcgcc tcaatagaat
    51421 caagtgcgct tttcaatgta tctagagcta actgtgccaa ttcttccatg ctctcttccg
    51481 gtttttcttc taccgttacg aagttttcgt ccagcacgaa gcgttccgcc atccgactaa
    51541 ttgacacttg attttgacta ccgtatcgtt gttgaattcc gtctgtcaat tgagtgataa
    51601 gtgaatcaat caattcccag ttgatgacga tctgtttttc gtttttgcca atataagcta
    51661 gattcacaaa tacttcgatt cgaccgcggc ttaactgctg tttaataagc tgacgaaaat
    51721 cgttttcaac aaagttcagg attttaggac ttcgtatttg aacatctaga aaacgctggt
    51781 tgacactttt tatttcaata tctaactgat acgcttttgt ttcgcggatg gctttgccaa
    51841 aaccagtcat acttttcatt cgacagggtc cttcctcatt acatattttc tattgctttt
    51901 tgcagttgtt caaactcttc gttcgtcaat gtcaggcctt tccccatttt ttcatggtct
    51961 ggcgcccaat ctcgaagatc gaattttggc gggcgaccat tccagctgac taggttcagt
    52021 tctttacgcc accccttgtt gttttctgac aatatagcga tttcttctac gatttcatat
    52081 gaaaattctt gtgccatggt tgttcctcct tgagataata taaatatagg atcagtaatg
    52141 tgtcaactgg ttgcttaagc aattcatgct gcaaacgatc cttgcgtttt ccttgtagca
    52201 gataatcaaa ataaacagtt ttcgtgcgct cattttgtat tttttgctgg tattttcgat
    52261 accttcgcca ttcttcagta cttaattgac caatttgtgc caataaatca tccggcatac
    52321 tttttatatc ttgttggcag atcatttgaa tcatcatgtc tacttgatag atttcattgg
    52381 gcagtaaaaa atgttttttt gctaaaagtt ctagcatcgc caatccgcat gtctctggta
    52441 cgaccctgtt cttatataaa ttacgcagtt tttgccaaaa ttttatgctt ttgaaaaaag
    52501 ataattctaa ctgaatttct tttgttaagt aagacaaaaa tcctcgccag tatgttcttg
    52561 caggtttaac agaatgaaat gtataccagt tcccatagta atagcctaat cgttttttca
    52621 tttccagata gcctaattgt aaatttaatt ggttcctttg gctatcaaaa agcagaaagc
    52681 tgcctagtgt ccacaatgtt tgacatttcc aatggataaa aatgtctggc atacgaattt
    52741 ttttcgctgg gcctggccct tgcacatcta cgacaaatgc ctctgttgct cctttgttaa
    52801 tcgcaatatc aataggtatt ttgttgcgat acccaccgtc tgcatattta ttttttccga
    52861 tctttcgata agccatagcg ggataaaatg aagcagaggc gagtatccaa tctggtattt
    52921 cttctgtttt tgtctgttgg atatcagtca ctacttccgc tagttctggc agtttagtag
    52981 acaccgtata taaacgtatt ttgggattat gtttgagtaa ggacaaatcc aaattgtctt
    53041 tgaccatctt ttccaatgga gcagaagaaa ccccgccttc aattagtgct gttttcgtca
    53101 tttggcgtct ttctcgatag aagcgttcac gaaggtcttc aactgcagcc atttctggta
    53161 acgcaagcac ttgtcttgtc gacagctttt tccataaatt cacagctttt ttcatatctc
    53221 cttgtaaaat caatgcgccg ttcaacgcac ctaccgaggt acctgtgata atctcaaagt
    53281 tgatatcatg ttccttcagc gcctgccaca caccaatctg ataagcaccg tgcgctcctc
    53341 ctccacctaa aacaagtgct gtatgataga ccagcttttt atttaattgt gtggttcctt
    53401 gatagccgtt tttatgaaaa atacgcaacc attcttctga tagaggagat tgaaataaaa
    53461 aacaacagtt ttctttaata aaaaaacgag cgcaagcttc catataccga aaaaattttt
    53521 tccattcaaa agtttcacct tcaatcaaca gattattaaa aataacatct cctctacttt
    53581 tagcaatagt aaaatagacg gtatattttt tcgatactgc tttaaaagca cattgctttt
    53641 ttgcagaacg ccaaaaagcg tctctacttt cttgatgact ttgaaaaaat ggaaggggtt
    53701 gttttgcttg ctggataggc gaatacagcg acattttctg tgaaaagtaa acttttttta
    53761 tctccatcgc gctctccttt ttcttcaagt ataccagtac gtcataaaaa ggtcatgagt
    53821 ctcgtattcg actttgtaga ttccataaga aaacaattca taaaacctcc tttaaataaa
    53881 aaaatacaaa aatcacaaaa attaattgaa aatgagagtg ttttcaatga aaacgtgatt
    53941 ttgtaatgga attttaaaat aaaagaaaca agctttttta atgcaaatgt tgtaaaataa
    54001 aagagattaa gaggaaataa gaggaggaac atgatgactg agtcagttta tgtacatatt
    54061 gataccacaa gtaatgctgt tttaacaaaa gggctgactg ctactgactt tgcaaacagt
    54121 atcgtgcatt ttcctcaaaa cttgctcttg cttgatccat ctgcttctgc tggagaatat
    54181 gaatcccata cagggctgaa agtaatccgt ggtacagaaa atattcagcg tttcttttcc
    54241 tcttctcgta acaggcgtgg attcgatgaa ttgaagtgga tcgactttac tgatttaacg
    54301 atgctgaaag aattgacacc tttagaaatt tcagaattat tatattttgg tcatatgaaa
    54361 acacatcttc attcgccgtt tttttataaa ctacagaata attttgtata cttcgatctt
    54421 aatgatcagc tgaatcggat ttattatcgc tatttagatg aattttatag gatttttgct
    54481 agtaaattaa gttcgatctt gtcagataag atcaatgtaa aaaaatcttt tttcaaaaaa
    54541 gaaacacctg ttgaaaaaat cagtgtggaa ttattgaaag aaatgcgtaa tttgatgcag
    54601 gaagggatca ttttttcttt tgatcaagtt ggtttgatcg atggtaaata tcgtatccca
    54661 atctatgtga ttgaagatta tatttggaaa ttaaaaggca cccggtatcg agaagaggaa
    54721 atcatcgcta ctttaatcta ctctgtcacc gatcgacact ggcaattggt agaagatgcc
    54781 gatctttctt atctgccatt gaagtagatc tatttcttat caaaaaataa aaaggaaaca
    54841 agaaactagg acatgattct gtctcaagtt tcttgcttct tttttattta cagctcctgt
    54901 cgtttatctg gcacaaaaat cgaaggagtc gtttgttgga tccctaataa aacgatgatc
    54961 gttacaatag ctgtactcaa cccgctggca ccattcatta cgaaagaaaa gagccaagga
    55021 ttcatccccc atagtgcata cgctccccag aaaaccactc ctgcaataaa atgccaaaaa
    55081 tatctggaaa gtgcgccaat caatgcacca aacacgatgc tttttctaat ttgtttcgta
    55141 ttatcgtcta catagccttt ttggacattt gaagccatga gccctgctgc gcctgcaaaa
    55201 gtataggcaa tcgggtactc aatcaacact tgaacgacac ttaaataata aacttgtccc
    55261 aacggaaaat gtaggatgcc ccaaatgaaa cctgccagca tccctgcctt tgtccctctt
    55321 cttaacgcaa aaagagtcaa tggaatctgc cctaatgaaa tagaaaaact gctgccgatc
    55381 tggatcggaa tcaacgacaa caccatcgct aacgctgcaa caatcgttcc ttctacccaa
    55441 actctatttt ttcccataaa aaaacttcct cctttgaata aaaaagtcac aaaggaggaa
    55501 gcagctttcg aaaatagtca aacagctgtt tattcacaat tcctacgctc gcataaccga
    55561 tacaggtacg aagggtttag aaatagattc aatctcagcc caattggact cccctttgtg
    55621 agtttattta ttatttattt tttgtttcaa acaatggact aactggtttg ttttcatgga
    55681 tacgtttgat tgcatctccc attagtccgc caacacttac ttcatcgatt ttgtcgattt
    55741 tacgatcttc tggaagatag atcgagtctg taacaactag acgctcgata gctgaatctt
    55801 ctattctttg taaagcaggg ccggataata ctggatgtgt acatgaagca tacacactag
    55861 ttgcaccagc ttctttcaaa gcattggcag ccaatgtgat cgtacctgct gtatcgatca
    55921 tatcatcgat cagtacacaa gttttgcctt tgacttgtcc aatgatattc attacttctg
    55981 caacatttgc ttttggacgg cgtttgtcta tgatcgcaat cggagatttc aaaaattccg
    56041 ctaatttacg tgcccgtgtg acaccaccat ggtctggtga aacaacgaca acatcatcgc
    56101 ctttgattcc tttttctaag aaataattgg caataagtgg cgcacccatc aaatgatcga
    56161 ctggaatatc aaagaaacct tggatttgga ctgcatgaag gtccaaagtc agcattcttg
    56221 ttgcaccagc tttttgaatc atgtttgcta ctaatttcgc tgtgattggt tcccgtgcac
    56281 gtgctttacg gtcttgacgc gcatagccat aataaggcat gactacgttg attgtttttg
    56341 cacttgctcg tttcagtgcg tcaatcatga tcagcaactc catcaagtta tcattgactg
    56401 ggctgctcgt tgattgaata acatagacat gcgatccacg aatactttct tcaatgttta
    56461 cttgaatttc tccatcacta aattgagtaa cagatgattt tcctaactcg acgccgactg
    56521 ctgctgcaat tttctctgct aatgggcgat tggaatttaa cgcaaaaatt tttaatcttg
    56581 ggtcaaagta atgttttgac atggggacct ccactttctt tttcacaact ctagaattct
    56641 acctaataaa tagtagtcat attttttaaa taaatcaagt gattttgcaa aagtcttagt
    56701 ttagataagg gagttttttt gcatatcctt ctttattgac ttgtcttgct ctcgcaattg
    56761 ccagcgcata ttctggaata ttgtctgtaa ttgttgaccc ggcagcaatc gaactgtttt
    56821 tagctacctc gacaggtccg atgatattcg tgctagaacc aataaagctg tggtcgccga
    56881 cagtcgtatg atgtttgttc tttccatcat agttgacgaa gacaacacca catccgacat
    56941 tgatttcttc tcccagcgta gcatcaccaa cataagtcaa gtgaccgact ttagttcctt
    57001 tgccgatttg agcatttttc acttccacaa agtttccgat atggacgttt tcgccaattt
    57061 cagcttttgg tcgtaaatgt gcataaggtc ccacatctgc atgtttcttg acatggctgc
    57121 tttcaatgac tgagttttca atgacgacgt gatcctcaat cctactgtct acgatttttg
    57181 aatgtgaccc gatgacacaa tcagaaccaa tgactgtatt tccttggatt tgtacacctg
    57241 cttcgatcaa tgtgtctgga ccgatttcta cgcctgcatc gatgtatgtc gttgctgaat
    57301 cgacaaagct tacgccattg accatatgca tctggttaat tcgctttctc atgatctcat
    57361 ttgctttagc taacgcgatc cgatcattga ctcccattga ttcttcaaaa tcatccgttt
    57421 gataagcagc aactgtatgg ccttcttctt ttaagatttc gatgatatct gttagatagt
    57481 attcaccttg agcattgttt gttccaactt tgcttaacgc atcgaacaaa gcttcgttgt
    57541 caaaacagta agttcctgta ttgatttctt gtacaagagc ttcttctggt gttgcatctt
    57601 tttgttccac gattttttct acgatcccaa tatggtcacg gatgattcgt ccatatcctg
    57661 ttgggttttc tgcttgtgcc gtcaagatcg ttgcacttgc attttttcct tggtgatatt
    57721 caaaaagatt gttcagcgtt tcagtagtca ataatggtgt atcgccactg ataactaacg
    57781 ttgttccttt ttttccttcc aagaaagaag cagcttgcaa aacagcatgt cctgttccca
    57841 attgttctgc ttgtaacgca tatttactgc gttctcctag ttgtgcttta acttgttctg
    57901 ctccgtgtcc aacgatcgta atcacttcat ctggtttcgt ttcactgacc cgattaatga
    57961 tatgttctac cataggttta ccagaaacgg gatgtaaaac tttatataat tttgacttca
    58021 tgcgggtacc tttccctgcc gccaaaataa ttgcataacg tgcgtccaac tgcgtcactc
    58081 ctaaatatag tttgctgatt tcagtttatc ccagtatacc cattttttca acaaaacaag
    58141 tgattttctt ttatcccagc gttttctgga taaaaaaata gatagaccat aacgggccta
    58201 tctatttggt aaccggtgct ctcctgccaa ctcctcggtc acaagtcaca ctactcataa
    58261 aacatgaaaa gctgtttttt gaaatcgttt cttgtgactt agagttaaac ggtaggctta
    58321 caacctcttc attaaacgtt tttcaatcag ctgaccttcg gtattagctc aataaacggc
    58381 aaaatatgag gagcaatttt tccgtttatt gagctaatac tcaggacagg acgctgattt
    58441 cacaacctct agataaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg
    58501 aaaaaatgtg gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcggcttt
    58561 ttcacaacct cttattctga aaaataattt cctggcacaa ccgtaatatt tttcgtttga
    58621 gtatctacat ctttgacata aagcagtgac gtataatcat cgatggcgcg atgaccgttg
    58681 aattttgatt cggcaaatac agtgatgcca acaagttctg attcgaattc ttcaatcaag
    58741 ctcttcattc cgttgactgt tccgccgcct ttcatgaaat catccactac aaggacacgt
    58801 gaaccacgtt tcaaacttct cttagacagt tccatctttt caattctttc agaagatcca
    58861 gacacatagt tgacacttac tgttgatcct tctgttattt ttgagtcccg gcgtacaata
    58921 acgaatggcg cattcagata ataggacaca gcttgggcaa taggtacgcc ttttgtggct
    58981 acagtcatta cagcatcgat tttttcacca aggtatttag aagcaatgat tcttccaact
    59041 tgacgcagca gttcaggttc tcctaacaaa tcagagagat aaacatatcc tcctggaagc
    59101 agacggtctt gttctgatag acgttctgct agagattcaa tatatttttt cgcctcttca
    59161 tatgaaattt cagggatgaa caatacacca cctgcagcac ccgggattgt ttccaaggtt
    59221 ccataccctc gttctttaaa tgttttcttg atgattccca aatcttcact gatagaagat
    59281 ttagcagatt cataacgttc ggcaaagctt gttaaggaaa tcaattcatg cgggtgattc
    59341 aataaatact gtgtcatgtc aactagacgt tcactgcgac gtactttcac ctattccaac
    59401 tcctttta
//
LOCUS       DARBDN010000009        56179 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000009 DARBDN010000000
VERSION     DARBDN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.009"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            228..1172
                     /gene="mvk"
                     /locus_tag="SCH06_000577"
     CDS             228..1172
                     /gene="mvk"
                     /locus_tag="SCH06_000577"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEG1077179.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            1165..2142
                     /gene="mvaD"
                     /locus_tag="SCH06_000578"
     CDS             1165..2142
                     /gene="mvaD"
                     /locus_tag="SCH06_000578"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEG1077180.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            2155..3240
                     /locus_tag="SCH06_000579"
     CDS             2155..3240
                     /locus_tag="SCH06_000579"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEG1077181.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            3237..4301
                     /locus_tag="SCH06_000580"
     CDS             3237..4301
                     /locus_tag="SCH06_000580"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEG1077182.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(4550..5353)
                     /locus_tag="SCH06_000581"
     CDS             complement(4550..5353)
                     /locus_tag="SCH06_000581"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEG1077183.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(5373..6215)
                     /gene="kduI"
                     /locus_tag="SCH06_000582"
     CDS             complement(5373..6215)
                     /gene="kduI"
                     /locus_tag="SCH06_000582"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HEG1077184.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(6231..7238)
                     /locus_tag="SCH06_000583"
     CDS             complement(6231..7238)
                     /locus_tag="SCH06_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEG1077185.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(7245..7889)
                     /locus_tag="SCH06_000584"
     CDS             complement(7245..7889)
                     /locus_tag="SCH06_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEG1077186.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(7989..8747)
                     /locus_tag="SCH06_000585"
     CDS             complement(7989..8747)
                     /locus_tag="SCH06_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HEG1077187.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(8874..10025)
                     /gene="fucO"
                     /locus_tag="SCH06_000586"
     CDS             complement(8874..10025)
                     /gene="fucO"
                     /locus_tag="SCH06_000586"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HEG1077188.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(10107..10418)
                     /gene="rhaM"
                     /locus_tag="SCH06_000587"
     CDS             complement(10107..10418)
                     /gene="rhaM"
                     /locus_tag="SCH06_000587"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HEG1077189.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(10420..11265)
                     /gene="rhaD"
                     /locus_tag="SCH06_000588"
     CDS             complement(10420..11265)
                     /gene="rhaD"
                     /locus_tag="SCH06_000588"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HEG1077190.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(11279..12535)
                     /gene="rhaA"
                     /locus_tag="SCH06_000589"
     CDS             complement(11279..12535)
                     /gene="rhaA"
                     /locus_tag="SCH06_000589"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HEG1077191.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(12532..13992)
                     /gene="rhaB"
                     /locus_tag="SCH06_000590"
     CDS             complement(12532..13992)
                     /gene="rhaB"
                     /locus_tag="SCH06_000590"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEG1077192.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            14145..15014
                     /locus_tag="SCH06_000591"
     CDS             14145..15014
                     /locus_tag="SCH06_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HEG1077193.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(15140..16039)
                     /locus_tag="SCH06_000592"
     CDS             complement(15140..16039)
                     /locus_tag="SCH06_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077194.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(16204..17028)
                     /locus_tag="SCH06_000593"
     CDS             complement(16204..17028)
                     /locus_tag="SCH06_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEG1077195.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(17039..18334)
                     /locus_tag="SCH06_000594"
     CDS             complement(17039..18334)
                     /locus_tag="SCH06_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HEG1077196.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(18350..18829)
                     /locus_tag="SCH06_000595"
     CDS             complement(18350..18829)
                     /locus_tag="SCH06_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HEG1077197.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(18835..19863)
                     /locus_tag="SCH06_000596"
     CDS             complement(18835..19863)
                     /locus_tag="SCH06_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HEG1077198.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(19880..20986)
                     /locus_tag="SCH06_000597"
     CDS             complement(19880..20986)
                     /locus_tag="SCH06_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEG1077199.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(21215..23812)
                     /gene="adhE"
                     /locus_tag="SCH06_000598"
                     /gene_synonym="adhC"
     CDS             complement(21215..23812)
                     /gene="adhE"
                     /locus_tag="SCH06_000598"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEG1077200.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(24117..24497)
                     /gene="yajC"
                     /locus_tag="SCH06_000599"
     CDS             complement(24117..24497)
                     /gene="yajC"
                     /locus_tag="SCH06_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEG1077201.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(24594..25739)
                     /gene="tgt"
                     /locus_tag="SCH06_000600"
     CDS             complement(24594..25739)
                     /gene="tgt"
                     /locus_tag="SCH06_000600"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEG1077202.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            25957..26655
                     /locus_tag="SCH06_000601"
     CDS             25957..26655
                     /locus_tag="SCH06_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEG1077203.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(26823..29462)
                     /locus_tag="SCH06_000602"
     CDS             complement(26823..29462)
                     /locus_tag="SCH06_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEG1077204.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(30081..31112)
                     /gene="queA"
                     /locus_tag="SCH06_000603"
     CDS             complement(30081..31112)
                     /gene="queA"
                     /locus_tag="SCH06_000603"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEG1077205.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            31305..32480
                     /locus_tag="SCH06_000604"
     CDS             31305..32480
                     /locus_tag="SCH06_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HEG1077206.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            32484..33125
                     /locus_tag="SCH06_000605"
     CDS             32484..33125
                     /locus_tag="SCH06_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077207.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            33122..34039
                     /locus_tag="SCH06_000606"
     CDS             33122..34039
                     /locus_tag="SCH06_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1077208.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            34036..34707
                     /locus_tag="SCH06_000607"
     CDS             34036..34707
                     /locus_tag="SCH06_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077209.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(35248..35736)
                     /locus_tag="SCH06_000608"
     CDS             complement(35248..35736)
                     /locus_tag="SCH06_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HEG1077210.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(35937..36203)
                     /locus_tag="SCH06_000609"
     CDS             complement(35937..36203)
                     /locus_tag="SCH06_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEG1077211.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(36203..36466)
                     /locus_tag="SCH06_000610"
     CDS             complement(36203..36466)
                     /locus_tag="SCH06_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEG1077212.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            36942..37127
                     /locus_tag="SCH06_000611"
     CDS             36942..37127
                     /locus_tag="SCH06_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEG1077213.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(37269..39092)
                     /locus_tag="SCH06_000612"
     CDS             complement(37269..39092)
                     /locus_tag="SCH06_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEG1077214.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(39690..42395)
                     /locus_tag="SCH06_000613"
     CDS             complement(39690..42395)
                     /locus_tag="SCH06_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEG1077215.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(42701..43648)
                     /locus_tag="SCH06_000614"
     CDS             complement(42701..43648)
                     /locus_tag="SCH06_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HEG1077216.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            43838..44107
                     /gene="rpsN"
                     /locus_tag="SCH06_000615"
     CDS             43838..44107
                     /gene="rpsN"
                     /locus_tag="SCH06_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEG1077217.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(44283..44645)
                     /locus_tag="SCH06_000616"
     CDS             complement(44283..44645)
                     /locus_tag="SCH06_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEG1077218.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(44656..45777)
                     /locus_tag="SCH06_000617"
     CDS             complement(44656..45777)
                     /locus_tag="SCH06_000617"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEG1077219.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(45793..46143)
                     /locus_tag="SCH06_000618"
     CDS             complement(45793..46143)
                     /locus_tag="SCH06_000618"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEG1077220.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(46273..47784)
                     /locus_tag="SCH06_000619"
     CDS             complement(46273..47784)
                     /locus_tag="SCH06_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEG1077221.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(48106..49458)
                     /locus_tag="SCH06_000620"
     CDS             complement(48106..49458)
                     /locus_tag="SCH06_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEG1077222.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(49611..50687)
                     /locus_tag="SCH06_000621"
     CDS             complement(49611..50687)
                     /locus_tag="SCH06_000621"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEG1077223.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            50883..52628
                     /locus_tag="SCH06_000622"
     CDS             50883..52628
                     /locus_tag="SCH06_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HEG1077224.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(52908..53345)
                     /locus_tag="SCH06_000623"
     CDS             complement(52908..53345)
                     /locus_tag="SCH06_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HEG1077225.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(53329..54702)
                     /locus_tag="SCH06_000624"
     CDS             complement(53329..54702)
                     /locus_tag="SCH06_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077226.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(55024..55512)
                     /locus_tag="SCH06_000625"
     CDS             complement(55024..55512)
                     /locus_tag="SCH06_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1077227.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(55534..56136)
                     /locus_tag="SCH06_000626"
     CDS             complement(55534..56136)
                     /locus_tag="SCH06_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEG1077228.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        15979 a        12182 c        10285 g        17733 t
ORIGIN      
        1 ttttttctag tcaaagaaga aaaaaagtca aaaaattctt aagaaaaaag tgttttttct
       61 ttagaaaacg tattcttagt tttacttctg agatggtttt agtaaaataa aggaggaatg
      121 ttttttgaga cccttagtgg acaaaaaaat tcgtgaagca gcgcaactcg ttttgggcgc
      181 tttatttttt gcttaaaaat cacttttacg tgagaaggag ttagattatg gcaaactatg
      241 gccaaggaga atcaagcgga aagatcatat tgatgggcga gcacgcggtt gtttatggag
      301 aaccagcgat tgcctttcct ttctatgcaa caaaagtcac cgcattcctt gaagagctgg
      361 atgcaatgga cgatcaactg gtttcttcct actattcagg aaatttagcc gaagctcctc
      421 atgcattaaa aaatatcaaa aaattattca ttcacttaaa aaaacagcat gacatccaaa
      481 aaaacttgca actgaccatt gaaagcacga ttcctgctga acgtggaatg ggatcaagcg
      541 ctgcagtcgc cacagcagtc actcgtgctt tttatgatta cttagcattt cctttgtctc
      601 gtgaaatact attagaaaat gtccagcttt cggaaaaaat cgcccacggt aatcctagtg
      661 gaatcgatgc agccgctact agcagcttgc agccgattta ttttacaaaa gggcatcctt
      721 tcgactactt ttctttgaac atcgatgctt ttttgattgt cgctgataca ggaatcaaag
      781 gacaaacaag agaagccgtc aaagatgtcg ctcacctctt tgaaacccag cctcatgaaa
      841 ctggacaaat gatccaaaaa ttaggatact tgacgaagca agcaaaacaa gcaatcattg
      901 aaaattcacc agaaacgttg gcacagacaa tggatgaatc acaatcactt ctggaaaagc
      961 tgacaatcag caatgatttt cttaatctat tgatccaaac agcaaaagat accggggcat
     1021 tgggtgccaa attaactggc ggtggacgcg gtggctgtat gattgcatta gcacaaacaa
     1081 aaacaaaagc ccaagaaatc agtcaagcac ttgaagatgc gggtgctgct gaaacttgga
     1141 tacaaggatt aggagtacat acctatgttt aaaggcaaag cacgcgcata taccaacatt
     1201 gctctaatca aatattgggg taagaaaaat gaagaactca tccttccaat gaacaacagc
     1261 ctttcgttaa cattggatgc attttataca gagacagaag tcatcttttc tgatagctat
     1321 atggtagatg aattttatct agatggcacc ttgcaagacg aaaaagcaac aaaaaaagtc
     1381 agtcagtttc ttgacctttt tcgtaaagaa gccggcctct cactaaaagc ttcagtaatc
     1441 agtcagaatt tcgttcctac cgcagctgga ttagcctcct ctgccagcgg gctagctgct
     1501 ttagcaggcg cttgcaatac tgctcttaag cttggattag atgatctctc tctttcaaga
     1561 tttgctcgac gcgggtctgg ttcagcttgc cgaagtattt tcggtggttt cgtcgaatgg
     1621 gaaaaaggcc atgacgactt aagttcttac gctaagccag tcccttccga ttctttcgaa
     1681 gacgatttag caatggtttt cgttttgatc aacgaccaga aaaaagaagt gtccagcaga
     1741 aatgggatgc gtcggacagt cgaaacatcc agtttttatc aaggctggtt agattccgtt
     1801 gaaggggatc tatatcaatt gaaacaagca atcaaaacaa aagatttcca acttctcgga
     1861 gaaacgatgg aaagaaacgg actaaaaatg catggaacga ctttagctgc ccagcctcca
     1921 ttcacttact ggtctcctga cagcttaaaa gcgatggatg cggtgcgaca attgagaaag
     1981 caaggcattc catgctactt tacgatggat gctggcccta atgtcaaagt tttagtggaa
     2041 aacagccatt tatctgaggt acaagaaaca tttaccaaat tatttagcaa agaacaagta
     2101 attactgcac atgctggtcc aggaattgcg attattgaat aaagggagat ttttatgatt
     2161 gaagtatctg caccaggcaa actctatatt gccggagaat atgcagttgt tgaaacaggc
     2221 catccagcag ttatcgctgc agtcgatcaa ttcgtgacag tcactgtaga atctgcacga
     2281 aaagtcggaa gtatccaatc tgcacaatat agtgggatgc ctgtacgttg gacaagacgc
     2341 aacggagaat tagttttaga tattcgggaa aatccttttc attatatcct tgctgctatt
     2401 cgcttgactg aaaagtatgc acaagaaaaa aacattcttt tatcctttta tgatctgaaa
     2461 gtaacaagtg agttagacag ttcaaatggc cggaaatatg gattgggttc tagcggtgcc
     2521 gtgaccgttg caacggtcaa agccttgaat gttttttacg cgttgaattt atctcagttg
     2581 gagattttca agattgcagc actagccaat ttagcagttc aagataatgg ttcctgcggc
     2641 gacatcgctg ctagctgtta tggtggctgg atcgctttct caaccttcga ccatccttgg
     2701 ctccaagaac aagaaactca gcattctatc agtgagttac ttgccctgga ttggccaggt
     2761 ctatccattg agccattgat tgctcctgaa gatttacgtt tattgattgg ttggacgggt
     2821 agccctgcct ctacttctga tttggtcgat caagttcacc gttcgagaga agataaaatg
     2881 gtggcttatc agcttttctt aaaaaatagt acagaatgtg tcaacgaaat gatcaaaggg
     2941 tttaaagaaa ataatgtaac gttgatccaa cagatgattc gaaaaaaccg acaattactg
     3001 catgatttat ctgcaatcac tggggtcgtc atcgaaacgc ctgctttgaa caaattgtgt
     3061 aatttagctg aacagtatga aggagccgca aaatcttctg gtgcaggtgg gggcgattgc
     3121 ggaatcgtaa ttgttgacca gaaatctggc attcttcctt taatgagtgc atgggaaaaa
     3181 gcagaaatca ctccactgcc gttacatgtc tatagcgatc aaagaaagga aaaccgatga
     3241 atcgaaaaga cgaacatgtt tcactagcta aagcctttca tgataaacaa aaaaacgaat
     3301 ttgacttcgt acggatcatc cataaccctt tgccgcaaat agcagtttct gatgtcgatc
     3361 taagtacaca ggcagttggg tttacactaa gcagcccatt ttatatcaat gcgatgactg
     3421 gcggaagcga aaaaacaaaa aaaatcaacc aagatcttgc aatcgtcgca agagaagcag
     3481 atttgatgat tgccactggt tcagtcagcg ctgccttgaa agtcccttct ttagccgata
     3541 cttatacgat tatgcgacaa gaatatcctc acgggaaaat cattgccaac atcggtgcag
     3601 ggacttctgt cgaaagagcc aaagaagcta tccgattgtt tcacgcagat gccttacaga
     3661 ttcatttgaa tgcacctcaa gagttggtta tgcctgaggg agaccgtgat tttaccaatt
     3721 ggaaagtact tattcaagaa actcaaacag ccattgacgt ccccctcatc gtaaaagaag
     3781 tcggttttgg catgacaaga gaaacgctca atgatctagc tgctttagga gttcatacag
     3841 ttgatatcag cggtcgaagc ggaacaagct tcacccagat cgaaaacgcc cgtcgctcca
     3901 agcgggaact gagttattta gctgactggg ggcaatcgac agtctcttca ttgcttgaag
     3961 caaatgaagc agacacttct atggaaatcc tagcctccgg aggtatccgc aatgcctatg
     4021 acatatttaa agccctttgt ctcggcgcaa atgccgtggg tacttcagga accgtactga
     4081 cgcatctgat gaatcacggc gtagaagaaa ctattatact gatgaagcaa tggcaagaag
     4141 agcttcgtct gctttatact atggtcggcg caacgaatac cgcggcccta caccaacaat
     4201 ctctgatctt ttccggacca gtgaaggatt ggtgcgaagc aagagggatc gacttagtga
     4261 agtatggaag acgcacagaa aagagcgtgg gacaaaagta aagaacactt ttgtctcacg
     4321 ctctaaacac gtacaaacgg cggaagtaaa agcaactcct tcggaaataa gctgaaattc
     4381 acaaaaattt gaaaagcaat tttcgtgaat tccttcttat ttcttggagt taaatgcttc
     4441 tgtcccagcc tcttttttcg aataaatgat gtttaatcag ctgtccttcg gtattcgttc
     4501 aatccgctga tttcacaacc tctccactaa acagtgtact aaagctcttt taaggttgtt
     4561 ttccgatata ggcaagtatg cctccgtcca catacaagac atggccgtta acgaaatcag
     4621 atgcgctaga agccaagaag acagatggtc cagccaaatc gattggctcg ccccagcgtg
     4681 ctgctggcgt acgtccaacg ataaattgat cgaatggatg acgttcaccg ttttcttgtg
     4741 tttcgcgtaa tggagcagtt tgcggtgtag caatataacc tggtccaatt ccattacatt
     4801 ggatattgta ttgaccgtat tcagaagcga tgtttttcgt cagcattttt aatccgcctt
     4861 ttgccgcagc ataagcactg accgtttcgc gtcctaattc actcatcatg gagcagatat
     4921 tgatgatttt accgccgcct ttttcgatca tatccggaat aactgctttt gaaacgatga
     4981 atggggcatt taaatccacg tcgattactt ggcggaagtc tgccgcatcc atttcgatca
     5041 tcggtgtccg tttgatgatc cctgcattgt tgactagaat atcaactgaa cctacatctt
     5101 ctttgatctg ttgaaccatc gcttgaaccg cttcttcatc ggtcacatcg cagacataac
     5161 cttttgcatc gatgcctgct tctttataat gcgctatacc ttcatcaact gattcttgat
     5221 tcaagttatt aaatacgatt tttgctcctg ctgtagctaa agagcgtgca atctcaaatc
     5281 caataccata gacagcaccg gtgactaatg ctacttttcc atctaaacga aacatatcca
     5341 tactaaattc catcattttc tctcccttat gcttatttta attgatccat ttgcaccata
     5401 tccatgtctg tataggtgat attttctccg cacattgccc agatgaatga gtaattgctt
     5461 gtacctacac ctgaatggat cgaccagctt ggcgaaataa tggcttgttc attgtctaca
     5521 actaaatgtt ttgtttcatc tggtttgccc atcatgtgga acacacgtgt atcttcattg
     5581 gcataatcaa agtagacata agcttccata cgacgttcat gtgtatgaca aggcatcgta
     5641 ttccaagcgc ttcctggttc taaaatcgta taacccattt gtaattgaca gctttcgcat
     5701 acatttggat ggatgtattg gtagatttta cgttcattca gtgtcaggcc ttcaccagtc
     5761 tccattggtt ttacttggtc gatactgatt tttacatttg gatatttatg atgagctgga
     5821 acagaactaa tatagaattt agctgggttt tcagcatctt gagaagaaaa tacaacatgt
     5881 cgtgtttctt ttccgatata gtatccgtct tgttttttca tttcttcttt ttgcccatcg
     5941 atctcgatga atcctggtcc accgatattg atcacaccta gttcacgacg ctctaagaag
     6001 taatcaacac ctagttcttt gtctaatgtg atttctaatt ctttttcagt aggtgtcact
     6061 ccaccaaaga tcattcgatc gttgtgcgta taagtcaaac tgattttccc tggttcaaat
     6121 accttttcta ctaaaaattc ttttctcaat tgttccgttg aataatgacg gatatcttct
     6181 ggactgtgtg tataacgtgt ttccatttct tgcattttct tctactcctt ctatcgaatg
     6241 atttttccag agccgcatgc taaaaattgt gcgacttctt cttgactaaa ttggttgcag
     6301 tccccatgga tcgtatgctt caaggcagaa gctgccgtag caaaatcaat gatttcttgc
     6361 ggagacatat tggataaaat cccatggagc acgccacctg caaaagcatc tccgccacct
     6421 actcgatcca cgattggggt gattctatgg acttgggatt ccacatattc atggttcatc
     6481 cacaatgtcc ccttcaattc attttcactt gctgaatgaa cggtacgctt ggtcgaataa
     6541 aacacctgaa tattcgggaa cttttcctgc attttttgat aataataaat tagaggttgt
     6601 tcttctgctt ctggcgcttt ctcgatacct aacaaataaa gagcatccat ttttccagct
     6661 gagcagatat ctactaaagg taaaagctga tggattactt cgctggcttc ttgctgtgtc
     6721 cataattttc cacgatagtt gatatcgaag ctgatcaggc agccagcttt ttttgcagct
     6781 tctatcacct gtttcgtcat tttttgccat tttttagaca aagctggggt gattcctgaa
     6841 acatgaaata tatctattcc ttggaataac tcctctagcg accattccaa atgatccatt
     6901 tcagcaaaac ttgatccggc acgatcatag atcactgagg cggcgcgttc gccactacca
     6961 gtttccatat aataagtacc tagtcttgat ccaccagata atacctgttt cgtatctact
     7021 ccataacatt gcaagtgctt tttgactgct tttcccaatg cgttatcagg tacttttgta
     7081 gcaaaaatcg cttcatgtcc gtaattagct aaagaaattg ctacgtttgc ttcccctccg
     7141 ccataatggg cagcgaatcg ttcacttgaa tcgatacggg ttccctgctc tgtggacaat
     7201 cgcaacatga tttctccgag tgtcactact tttcccataa gcagctacct cttgatttct
     7261 ttcatttttg ctgcatactg ttgcgcgact tccgttactt tgtcaaaatc tcctgtagct
     7321 gcgggtgcta aaaggttccc acctactccg actgttacga caccagcatc gaaccactct
     7381 ttcatattgt ccagactcac accgccagtt ggcatgatat tgacttgagg catcggcgcc
     7441 ttgaaggcag aaatgatact tggtccataa gcgcttccag gaaatagttt gacgatatct
     7501 accccgcttt tcagcgctgt tttgatctcg gtaatagtca tacatcctgg taagtaagga
     7561 atttgataca gattgcacat ctctgccgtt tcttgatcaa aggaagggct aacaatatac
     7621 tctgcgccag ctaagatagc caagcgagct gtgacagcgt ctaatactgt gcctgcgcca
     7681 atcactattt ctggttggtc tttgtagaat gacaaaagtt ctttgattac ttgatctgct
     7741 tgagggactg taaaagtcaa ctcaatacca gttagaccac ctttgatgat tgcgtggcaa
     7801 gcattcaaag cttcttcttt gctttttccg cgtaccaccg caatcactcc ggcgtttttc
     7861 aatcgagata aaatatcaat ttttttcatc ttctccacct atttcctatt tagaaatttt
     7921 attttataac ttggaaatct atacccatat tatacggcag aaaagaaaaa ttgcaaacgc
     7981 ttttttcatt atttttgaat tctttgctcg atttcgcttt ttgtttgctt gagggcactg
     8041 attatttgtt cttttgtctc atctgttaaa cgatatttcg gcatacttac actaaatgca
     8101 ccaatgattt gttcgttttt cacgattgag gctcctatac aaaaaatatc acgttcgatt
     8161 tcttcatcgt caaatgcgat gtgggtttct tttaccgttt tgatttcctt tttcaaccgt
     8221 aatgcattgg tgatcgtata ttctgtgtaa gggatcaacg gatgcttttc aagataatca
     8281 gtgtactgct cttcactgaa ttctgctaat acggctttgc ccatcgcaga attgtataat
     8341 ggtcgggtga ttccgatttt tgaagacatg cggatcgttt gatgttttgg atctagtttg
     8401 ttcacgtaca agatctcatt gttgtccaat acccctaagt ggatagtctc atcgatcttt
     8461 tgctgcagct gttctaaaaa cggtaaagtc aactctacca aatcgatttg ttcaatgttt
     8521 ttattcgcgt agcgaataag ctttgcacct aaacgatagt ttttctctga atttttattt
     8581 acgtagccga tcatcaacaa agtatctagt attttcaaga ctgtagaaga ggtcattccc
     8641 acaccctttg cgatcgtctg caaagagaca tcttggtttt ccgctaaata gtctagtatt
     8701 ttagaggctt tgatcaatac agttccataa ggctttttat tttccatata atattctcct
     8761 atttctttat aagaaaaatt atagcggaaa taccatcaat ttaaaagaga tatccagata
     8821 taaactacca tttctcttta caggcaattt aatgttgaag atccgcttcg tttttacatc
     8881 aaactttgat ataaagcaat gatttcttct actgtcgttt ctcttggatt tcctggtgtg
     8941 catacatctc gcaaagcatc ttctgcaatt gctggaatat ctgcttcttt tacacctaat
     9001 tcagaaatgg tttctgggat tccaaccgct ttgctcaacc gatcgatctc accacaagcc
     9061 gcttctctta catcttctaa agacatttca gctgctcctt taatccctag aacaagagcg
     9121 atctcacggt acttttctcc agtatattct ttgttatatt tcatgacagt tggcaaaagt
     9181 gctgcacacg ctacgccatg aggaatgttg taccatgcac ttaacgggtg agccatcccg
     9241 tgtaccagtc ctaaaccgac atttgagaag cccattcccg caatatactg tcctaatgcc
     9301 attttttctc gcccattttg atcgccatct acagaagctt ccaaagaatg gccgatgatt
     9361 tcgattgctt ttaaatgcag catatcagtc atttcccaag cgccttttgt gataaaccct
     9421 tcaatagcat gcgtcatagc atccatacct gttgatgcag ccaatttttt cggcattccc
     9481 atcatcatat cgctgtcgat gaacgcgacg attgggatat catgaggatc aacacaaaca
     9541 aattttcggt gatttacttc atctgtgatg acgtagttga tcgttacttc tgctgctgtt
     9601 ccagaagtcg ttggtatagc taatataggt aaacatggat ttttcgtatc agcaacacct
     9661 tctaaactaa tgacgtctga aaactctgga ttcgtcaaaa taatcccaat ggcttttgcc
     9721 gtatcgattg gcgaacctcc accgattgcg atcaaacagt ctgcctctgc ctctttaaca
     9781 aaagccactc catcttttac attttggatc gttggattag gtacgatccc gtcgtataaa
     9841 gcataagcga ttgctgcttt atctagaagt tctgttactt ttgttgctat accgtgctcg
     9901 atcaatcctt tgtcagtaat gacagctgct ttgccgaatc ctcgctgctg aaattcaggg
     9961 acgatcgact caatcgctcc ttttccaaaa tacgatgttt catttaaaat cattcgatta
    10021 ctcattttct attcctccta atttgtatta tttttcacaa taaaaacgaa agaaccccaa
    10081 gcaaccggtt gcccagttgc ttgttgctac agttcaaaga ctggcatcaa ttcccaactg
    10141 actggagagg catctggatt tgtctccatg atatcttcca tgtacttcca ccatttttga
    10201 ttgatagatg tatttgccat tttttcccat aacttttcat cttcgatcac taagtaacca
    10261 aataacaaac ttgtactcgg atcaagatag atcgaatagt cgatgacccc gtgttcacga
    10321 agtgctgtac gcatttctgg ccaaagttca tcatgtcttt ttttgtattc ttcttgtttt
    10381 tctgggtaaa ctttcatgca aaaagctttt ttcaccatgt cagacacctg ctttcgtatg
    10441 aacttcctcc aaataacctg cttttggagt gacaccaaac gcatctgcta aatgccacag
    10501 gttttcgtcc gtgattgttt gcaagattgg tccttgcgct ttgacgtacg tatagacttc
    10561 tgctgccttt tctgctgtct cgatcaaacc aaagacttca tccatgtctt ttcctgaccc
    10621 gtagattcca tgttgtggcc ataaaaccaa tcgagtttct ttcatttttt cagctgttgc
    10681 ttccccaatc tcatttgttc ccggaaccat ccacggaatg atggaaattc cttctggaaa
    10741 aacaactaag cattccgtac acatttgcca tagcgtacga ctaaaggaac gttcgtctaa
    10801 ttcatgcgta aaactcatcg ctaatagatg actagcatgg caatgcataa cgatccgatt
    10861 atctgggtct acttctaaac gggcgatatg actcatgaaa tgacttggca actcgcttgt
    10921 aggaaggcat tcgttttcca gcccccacaa aagttccagt gttttgccat cttcagcaac
    10981 tcgaacgatt ccaagattct cggcaggttc gctcgctaca tttttaaaat atcttcctga
    11041 accagttaca ataaaatagc atcctgctaa acggctggca tcaaaaatca tcgagatgcg
    11101 gcggatcact ttttcaggat ccaagaacgg tgtgatctct tcttctttta gtaaataaga
    11161 aatattcccg ccatttcttt catcccatcc caagcgataa agattcgacg tcgtttcgat
    11221 catttctttc acataaggcg cttgtaaaat atctattttt ttcaatatag ccacactcct
    11281 attttcttaa ttccaacacg tctttttgat attcctggac ttcttccagc caatccaaac
    11341 caactggaac ttgatttttg taacagaaat aattccatac atcggcatac gggaaatctt
    11401 tcaattcttc cgtataagcc attcttgaag taaagtcaaa agccagctcc atttctttca
    11461 atcgctcaac tggttccagc atagctttca gcagtgcttt ttgtgtattt ctcgtaccga
    11521 tgacccaagc agcgatacgg ttgatcgttg catcaaagaa atccagaccg atatttgttt
    11581 tttccaacaa ttcgttacgg actaattctt tagcgatttc ctgcaattca tcatccatca
    11641 aaaccacatg gtctgaatcc caacgcactg gacgggaaac atgcaacatg attcctttgc
    11701 tgaataaagc taatgaagat aatttattgg aaatcacttc tgttggatga aaatgtccag
    11761 catctagaca aacaagtttg tcacgagtca acccgtaacc catataaaat tcatgggaac
    11821 cgactgtata agcttcagcg cctaaaccaa atagtttgct ttctactgca tcttgtacat
    11881 accgttcatc taactcttct gtaaaaattt catcgagtga ttccattaaa cgttcccgtg
    11941 gggtaaaacg atcaatcgga ttatctttca tcccatcagg tacccaaaag ttattgatac
    12001 ttgtttgccc agtttctttc ccaaagtact ccgcgatttt gcggcttctt ttcccgtgtt
    12061 cgatccagta ttcacgaact tctttatctg gatgagccaa tgtaaagccg tctttcatca
    12121 ttggatgcga aaagaaagtc ggattgaagt caagaccgat ttcttctttt tttgcccact
    12181 ctacccattt ttcaaaatgt ttcggctcaa tttcatttag atcgacagat tcttctgtat
    12241 ccaaatagat agcatgaagg ttcaatttgt gtttgcccgg tatcaacgaa taagccttct
    12301 ccagatcttg tctaagctct tcaggtgttc gtgcggctcc tggaaaattc cctgtcgcca
    12361 tgattccacc ggtcaattcg ccatccggtg tcaagaaacc tttgacatca tctccttgcc
    12421 agcaatgcat agaaattttg atgtcctgta tcttttctag tacagcatct gtatctacac
    12481 cgatagttgc atatttttct tttgcttgtt cgtaatttct ttcaatcgtg ttcatacgat
    12541 tactcctttg attttattca cgtaccattc catcgtgttt tgcttatttt catctgggta
    12601 aaaagtttca catggaaacg actgtttgat tacatttctt gcttgttcta tattcgaaaa
    12661 ctgacctgta ctgagcattt gcatggcaac attcccgatt gctgtggctt cactaggtcc
    12721 tgcttctaca atgattccgg cataatctgc tgtcaattga ttcagtagac gattattcga
    12781 tccgccccct acgatgtgca gcttttccaa tttcgttcca gttaagtgtt ctactttgat
    12841 cagctcttgt gcgtaacaaa gagcaagatt atcatacaca caacgagcga tagctcccga
    12901 tgagacaggg actggctgct ctgtttcaaa acagtattgc tgaatctctt ctatcatatt
    12961 tgggggattc aaaaatcgag ggtcattgat ttccatcact tgctgcagcg gtttttcttt
    13021 tgcagcaagc tctgccaatt ccgcataact gtactcgtac tcttgcattc gggcaacttc
    13081 ctggatcaac cacatcccca tgatgttttt caaaaaacgc accgtgttat gggcacccca
    13141 ttcattcgta taattttcag aaaaagcatt gcgagaaaca ttggcgatct ttgtttcaat
    13201 ccctaaaagc gaccatgtcc cactgctgat ataaccccaa cgttctcctt gacctggcgt
    13261 tcctaataca gctgacgccg tatcatgact tgctactgtg ataaaggtca catctggcaa
    13321 atcatatttt gaaaattgtt ctttttgcag atctcctagt atcgttcccg gctctgtcaa
    13381 tggtggaaat aattccttcg agacaccgat tttttcaaga agttctattt cccattcttt
    13441 tgtccctgca ttcagcagct gcatagtaga tgcattagtt ttctccgtca ccatgttacc
    13501 agtaaagaca taccctaaat aatcaggtat cagtaacaat ttatgtgctt ttgccaaatt
    13561 ttctttttct tcagcaaaca attggaacaa ggtattgaaa ggctggatct gaatccctgt
    13621 ctgctcatac aacttatcta gagaatagat ttcagaaaac tgttctactg ctccattggt
    13681 acgcttgtcc cgataagcaa tcggatcatt tatccgatcc ccttgttcat caatcagaca
    13741 gtaatcgact gcccatgtat cgatccccgc aaaaaggcga tcaatccctg tctgctttaa
    13801 tttttcaaat ccaatcaaaa tctctttgat aagataatcg atcttccagc gatcgtgacc
    13861 gtctttgttc cgaaagccgt ttttgaaccg gtgtacttct tccaagatca aagaaccttt
    13921 tgcatccctc gtacttttca ttagtcgtcc gcttgatgca ccgatatcga tggcaacaaa
    13981 tgttggattc atttctccac ctcttttact ttattgttga ttagcacttt attaataaag
    14041 cgttatcatt tattgacaat gctatcataa tacagaatct tatattttgc ttcacactat
    14101 tttggtatat aattgcatta tcttgacaag ttgggagtgt ttacatggat tactgggaaa
    14161 aagccaacca ctcatggtcg gaagactcaa aaagagtgat cttgacgcct acacaaagaa
    14221 gcaggaattt atttttttat atccaagaaa tcggttactt caaagcacca atcccttact
    14281 atactgaacg agcacattta ccttcttact tgataaagtt tactttgtct ggcaaaggtt
    14341 cgcttacata taatgataat cagcaacagc taaaagctgg agacttattt tttattgact
    14401 gccaagaata tcagcgttat caaacgatca gcgaagaacc atgggaaatg gattggatcc
    14461 atttgaatgg tcagaacgtc caatcatttt atcaggagtt cacaaaagac ggccataaca
    14521 ccttccattc aacaggagat ccatcagaaa acaagatcca ccatttgatc acagaattga
    14581 tccacatgca acaaggcacg aatgcccgta ccgatttcca gtcctctgta gctatccacg
    14641 agttgctgaa tgaactgatt ttgcaaaagt atcagctaga tttcgaagaa gaggatattc
    14701 ccgcctacgt ttacaaactg aagcaatact tagacgaaca tttcaaagaa acgattacac
    14761 ttgatcaatt agaacaacaa ttcttattga ataaatatca gctgagcaaa gatttttcca
    14821 aatttatcgg ttctccacca atcgattatt tgatcagcaa aaaactttct tacgctaaag
    14881 accttcttcg gtatacagaa tttacggttc gaatgatttc cgaagaaata gggattgaga
    14941 attttgctta ctttagccgc ctgttcaaag caaaaacagg actatcgccg agagactttc
    15001 gtaaattcag ctgattcata taatatgtac gtcatttttt caaaatattt tgaaatatat
    15061 agataaaaat aaaataaccg cagtttctgc ttctatgtaa acaacagcag ctactgcggt
    15121 tattttttag tgatcattct cattgttcat cttcaaaatg ttcataatga accaactgtt
    15181 tctgtgtatc acgtttcaaa aattctttag gcgttatgcc gaactctctc ttgaatgctt
    15241 tcagaaaatg cggataagaa gaaaaaccac ttttactata tacagcacta gagctgcggt
    15301 attctcgcaa caagtgcttg gcatagatca gctttttctt cattacatac tgatgaaacg
    15361 taaatccagt gtacttttta aattctcgtg tgatatggta tttgctgaca aaaaactgct
    15421 tttccatttc ctctaaagaa agcggatgag ataaattttt tgagatatat tgtaacattt
    15481 gttccacacg ctcattagga actacagcat tctgttcttg cgcactctct tctttttgta
    15541 caacttgatt gagaaaaatc aagtattcta ccagagcttg ttcatatttt atgtcttcac
    15601 cgtaaatttt tttatcagga ggatggtcga taaatgataa tttttgcttc aatacttcct
    15661 gttctatttg caatacacga ctcctcttct ctcccattgg ttgaaaacaa gccgatagat
    15721 tagaccatgg cgtggaacga ctttctagaa aagaaggggt gacaaagata tagacacgct
    15781 cgaatacatc tgaagattgg cggacgatac gatgcaaatc attggaatgg atgagcagca
    15841 cacttcctgc tttgatcgta aattgtcgtc cgttcaaata aaaagtcgct tctcccttta
    15901 atgtagcatg gatctcatag aaatcatgat gatgatagat cgttttattt tggctgacga
    15961 catctttgac atgatagatt tcatactgat cagaaaccat cgtattgact tgttcaccgc
    16021 tgattttctt ttggagcatg tgccgcacct ccttttgttc acttatgcac aattttatta
    16081 taccacgttt tttgtaatca aaaagagctg cttttatata ctcttataaa aaagaagaga
    16141 cgtggcatct tctagccccg ccccctccat tctaaatatt agttaaccaa cgtcttcttt
    16201 acattattca agaagacttc ttccataacg aatcccatca tcttttgttt cttcaagaac
    16261 cacatacagg tacggacgat tcttcatgat gatttctttg atttttgtgt actcgatcac
    16321 accgtctccc aaatttaccg gcacgatttt ttcctgttcg acacgaaaat ctttcaaatg
    16381 aaccgcacat atcttttcac caaaacgttc aaaagcttct tctaccaatt ggacttgttc
    16441 ttgataatca ctacttgtga tcaaattggt cggatctaaa atgattccta gatagtccga
    16501 atctactgct tggatcagct gctctaccct tgctaaagaa tacaccggat gattcaaacc
    16561 tggttctatc cccaccatca tttggtattt ttctccagct tttaccaagc gacggataac
    16621 ggacacagct tcagcaaatg cttcatctgt gaaattttct tccgtatatt ggatttccgg
    16681 caaaacacat ccagtttccg aagcaaccat cgacgcacca aaggaagaag catagcgaag
    16741 atactgctcg aactttgtca gcaactcttg tcgtatcgtt aaatctggat gaatcatatt
    16801 gatatagcaa cttaaaattc ctacggtcac ttcttgcttt tctaaaactc gtttgacata
    16861 atttcccatc ccagaattga tctcatttgc gccagaaggt atttcaggaa acgaaagacc
    16921 taaggcgagc tgcagtgtat gaatcccttg ttcttttgtt ttttctgcaa gatcttctat
    16981 cgtttggact tcggaaagat catgtcctct aattgtaatg ttcaacataa ctattctcct
    17041 aactcagcat attgggtagc cacatgacga tttgcgggaa gtaagtaatc aaaaacaaga
    17101 cgactaagat aaccccataa aaaggaagaa gcggtttcag cattgcctct gcttttacgc
    17161 ctcctacact tgcaccgaca tatagtcctg tacctactgg cggcgtgatg gagcctacac
    17221 acagattcat gattgaaaac aacccgtaat gtacaggatc aacccctaca cttgtgacga
    17281 ttggtaaaaa tattggtgta aaaatcaaga tagcaggcgc cacatccata aacataccca
    17341 ccagtaataa cacaagattg actaataaca gaataataaa tttattatcc gttacgccca
    17401 taatcaacga actaattgcc tgaggaatac cggtaaacgc catggcgaaa gacatcatgg
    17461 aagaagtagc caataagaac atgatcgtcc ctgacattgc tactgattga aacaacatat
    17521 taggtatatc ttttagtttt accgttttat agtaaaacat agcaatcaac agggagtaaa
    17581 tgacagctat cgctgaagct tctactgctg taaatatccc cgtcaagata ccaccgataa
    17641 tgatgacaat caatagaagg ctaggaatcg cctcttttat tatttttcca gcatgagcca
    17701 tctgtccttt ttcgacaaca gggtatttat tctttttagc aacgatgaat gctactagca
    17761 tgattcctag cgcccacaaa gcgcctacga gataacctcc cataaacaaa gcagagatcg
    17821 aagcaccacc agcaacaagt gaatacatga taaaagcagt acttggagga atgaccatac
    17881 ctgtcggagc tgacgcgata ttgaccgctg tcgcaaactt ccggtcatat ccttcttcca
    17941 cttgctgagg gatcaacact ccgccaatcg cggtagaagc ggcaatggcc gagctagaga
    18001 tggaaccaaa taaagcattc cctaacacat tcgtatgagc caaagccccc ggcacgcgcc
    18061 cgacgaacaa catcgcaaaa tccactagtt tcttagctat ccctccatta ttcatgataa
    18121 tgcccgagag aacgaaaaac ggaatagcga tcagcgaaaa actattgata cttcccacca
    18181 ttttttgagc tgaactaaaa gcagaaacat caaacggtat aactaacaat aaagtcatca
    18241 tcgatgagaa tgcaatactt atagcaatcg gcatccctaa tacaagcaac acaacaaata
    18301 caaaaaataa cactaatccg gcttctattg ccattttatt cctccatttt tatatttttt
    18361 cttgaattgc tggcttgttg cttaatgtat cgattagatt gatcaggcta tagataatga
    18421 tgagtacccc cgatacaggt actgacagat aaacatatcc cataggaata cttaaagaag
    18481 gcgagatctg ccccattgtc aatgtgacag cattccatcc gccatacacc atgatcatcg
    18541 cagcaaatac cagaaataaa ctttgaacaa caacttctaa aattttactt tttttgccag
    18601 ttaatttttc acttaaaacc gttacggcta aatgtgcttt ttgtcccaca acatacgcgg
    18661 aagacaacat ggcaaaccag acaagaccga atcgaacaag ctcttccgtg accgtatttg
    18721 gatttcctaa aaccgttctg gaaaatactt gccataaaac aacagcgacc atcccaacaa
    18781 gcaaaacagc tcccaggatc tctaatacct tgtttaaaat cattttcatc acagctacgc
    18841 tccttgctct tggatctttt gataaaggtc tttgtaggta ggatcgtttt tgaatatatc
    18901 atgaagtggg gcaactgcct ctcgaaacgg tgtattatct acatcattga attggactcc
    18961 atgttcttct tgtgctaaag ctttttcttc ttcaattgct tttgcaaaag cttcaatttc
    19021 aaaaaccgtt gattctttcg ctgcttcttc aatggctttt tcctgctcat cagttagctg
    19081 ttctttgatg gcatcattca tgatgatgat atctggcaca cgtgtatgct catcatagga
    19141 atagtattta gccacaccac catgtccagc tgtatacaag acaaattcat tgttttctga
    19201 tccgttgatc aaattggatt gaagagacgt gtacacttca tcacttccca taggtacggg
    19261 cgaaccgcct aaaagctcta ccattttgat agcggtttcg ctttgcatca cacggatctt
    19321 ctttcccttc aaatcttccg gcgtatggat cggaccgtct accatataaa agctgcgctg
    19381 accagaatca taataggtca atccggtaaa tcctaaattt ttggtcgatt ggtagattgg
    19441 ctccattatt tcttcattat ccatcacctt aaagaaatgt tcttcatcat tgaatagata
    19501 aggaactgaa aaaatcgaat aatctttaga gaaactttcc aacgctgagg cacttacttt
    19561 tgtgaaatct actgctcctg actgtgtcaa ttcgatcagt tcacgttctc cacccagttg
    19621 tccatctggg aaatactgga tctgtacgga accatctgtt ttttctttta ctaaacgccc
    19681 aaattcattc attgcatcaa ttactggctg gctgttgctt gcataagcaa agcgcaaggt
    19741 aactatctca tttacatctg catctgcgac agttgccaca ctagaattat ttccgcagcc
    19801 gcttagacct agcagaccta ggctaagcga acttgctgca aacagcagtg atgttttttt
    19861 catatgggtt tcctttcttt taacaataag agacgagcaa ttctgtcaaa caaagcaccg
    19921 ttaacgactg tccataaggc attgctgtga ttccgatatt ccgataaaaa tctaaactgt
    19981 cccccattcc tgtcccgatt gaaacgtttt gaacttctcc tttttcatcg atttgttcaa
    20041 gcaatccttg gatagcacga taagcgactt ctttatattc ttgtggtaaa taacgtttat
    20101 ggaccgcttt caaaataccg taagcaaatc ctgcagttgc agaagattct acgtaagaag
    20161 aaggatcatc caacaacgta tgccataaac cgctttcaga ctgataagtt tttaatgcac
    20221 gcacttgtgc ttcaagtgtt tcgatcaata atttgcgcaa tgcatcttct ttcgataatt
    20281 ctaagatttc aatgatctct ggaatagcaa tcgtcaacca gcagtttcca cgagcccaaa
    20341 atgcttcggc atagttatga tttccttcaa acgtccagcc gtgataccac aatcctgttc
    20401 gtttatccat caagtatttg atatggatca taaactggta acgagcttct tctaaatatt
    20461 ctgggcgatt caacagtttc ccgatttttg ccaaaggaag cactgtcatc atcaatgtat
    20521 cgtcccacaa ctgattctta ttttccggtc catatgtggc atgctgtaac ccgtcttcat
    20581 ttgtccgagg catgtcattc atgacccatt ctgcccattg ttctaaataa ggcaaatagc
    20641 gtgaatcttt cgtgtcttca tacaagtaag ccatagtcaa tagcggtgcc attgtattga
    20701 cgtttttggg cggagcgcct tcttccatac gatcctcaaa ccattcattg accacttgat
    20761 aagcgcgagg attttttgtc atctggtaat ttttataaat accatataga ccgacacctt
    20821 gtggccaatt ccacactgtc cagcttttgt catctacttt cagtccatca aagtccaaca
    20881 aaaattcacc attatcgtct ttgatcgttg tcaggttttc aacgagcagg tcaatttttt
    20941 ctttcactaa ttctttaggt acaaaaatct cttctttaat aatcatcttt acgccacctt
    21001 tttaaacgct ttcattttat atccttaata tagcagtaat accgtccact ataaatatcg
    21061 ctttttgaac aaaaactgtc taaaattgac ctaaatgtta aataacaaaa gtaactttca
    21121 gttacttgga aattaaaaaa agaacttgga gaaacaacgt tttccaagtt ctttttcatc
    21181 tattttctta tcttttttct acgctttctt ttgcttatcc gttgtaagca tcaatgatga
    21241 tctgtttcaa ttcagagatc aatggttctt tcggattagc tgtcgtacat tggtcttcgt
    21301 aagctaattc agccatacgg tctacggttg tatctagtgt ttcttgtgtg actccttgag
    21361 cttttagact catgttgatg ccgacagatt ttcctaattc ataaacagcc gttgctaaag
    21421 cttcgactaa ttcctctgtt gtttcgcctt tcagacctaa gaattttgcg atatctgcgt
    21481 aatctgtatc tgcacggaaa tagtcatatt tagggaacat cgcatgtttt tgtggatctt
    21541 ttgcattata gcggataata tgcggtaaaa gaatcgcatt tgtccgtcca tgagggatcc
    21601 cgtattcccc gccgatttta tgtgcgactg agtgacaaat acctaggaat gcgttagcaa
    21661 acgccatacc agccattgta gaagcgttgt gcattttttc acgtgattcc atatcaggtg
    21721 tttttactga tttttctaaa tagtcaaaga ctaacttgat tgcttgtagg ctcaatccac
    21781 gtgtataatc tgaagccatg actgaaacat aggattcgat tgcatgtgtt aacacatcca
    21841 tcccggtatc tgctgtgaca gatgctggaa ctgacatgac gaattgagga tcgacgattg
    21901 cgacatctgg cgtcaatgca taatctgcta acggatattt cacatgtgtt tcactgtcag
    21961 tgatgaccgc aaatggcgtt acttcagaac cagtccctga tgttgtcggg atacatacga
    22021 attgtgtttt ttctggtttg tcgatcttat atgtccgttt acggatatcc aagaattttt
    22081 gttttgcacc aaagaaagat gtgtctgggt gttcatagaa catccacatt cccttagctg
    22141 cgtccattgc agaaccgcct ccaagagcga ttactgtatc tggcttgaag tctgccatca
    22201 gtttcgttcc tgcgtatacg gtatttgtcg atgggttcgg ttcaacatct gagaagactt
    22261 cgatcttcac atcattttta cgtcgtgcca atacttcacg aactgtatcg cagtaaccga
    22321 attggaccat accagggtca caaacgatca tgacacgttc aacgttttcc attttctcta
    22381 agtacaatag agagttcttt tcaaagaaga tttttggcgg taatttgaac cattgcatgt
    22441 tatttctccg tttcgctaca gttttgacat tgattaagtt tacagcagag acgttacgag
    22501 aaacagagtt cttaccataa gaaccgcatc ccaaagtcaa tgacggaatc atttcgttat
    22561 agatatcacc gatgccgcct tctgcagatg gtgtattcac taaaatacga caagctttca
    22621 ttcgaagacc gaatttgaca tgcaactctt cgttttctga atggataact gctgtatgtc
    22681 ctaatcctcc aagattcaac ataccttcac acaaatcaaa cgcatggtcc gtgttgttag
    22741 ctttgatcat ggcaagaact ggagaaagtt tttctcttga tagcggataa tctgggccta
    22801 cgccttccaa ttcagcaatc agcattttcg ttccttttgg tacactgatt cctgccaatt
    22861 ttgcgatttc catcgcagaa tgtccaacga ttgatggatt gaccgcatat tttccttcgt
    22921 tcatcactgc atcttctaat ttttgcaatt catctggttt tacgatataa acttggtgtg
    22981 cttggaattc tgcttttact gctgcataga tttctttatc cacgatcaca gcttgttcag
    23041 aagcacaaat cattccatta tcaaatgttt tcgaaacgat caaatcgttc actgcacgtt
    23101 taatttttgc tgttttttca atataagctg gtacgttacc tggacctaca cctaaagctg
    23161 gttttcctgt agagtaagca gacttgacca ttccagctcc acctgtcgct aagacgatcg
    23221 cgatacctgg atggttcatt agcatagaag tcgcttcgat cgaaggatgt tcgatccatt
    23281 ggatacaatt ttcaggagct ccggcagcga tagcagcatc acgtaccact cgtgctgctt
    23341 ctgcagaaga tttttgggca cttggatgga aagcaaaaac gattggattt cttgttttca
    23401 acgcgatcat tgatttgaaa atcgttgtgg aagtcggatt cgttgttgga gttactccgc
    23461 aaaccacacc gactggttca gcaatttcaa tcaacccttt ttggacatct tcattgatca
    23521 caccaactgt tttatcatgt ttgatattat gccaaatata ttcggacgca tacatatttt
    23581 tgattgcttt atcttcgtaa acaccgcggc ctgtttcctc tacagccatc ttcgctaatg
    23641 gcatatgttg atccaaagct gccattgcca tttcatgcac gatatggtct actttttctt
    23701 gatcaaagct ttccatttct ttcaatgctg catttgcttt ttctgccaaa tcatcaatca
    23761 ttgcttgtac gtcaattgtc ttcgtttttt ctttttctat tactttagcc atcattatcc
    23821 tcctaatggg tcatggttat ttgttaaata attcacatgt atatcataca atatttattt
    23881 ttctatgtaa acactttttt gtgatttttt tcacagttat ttttaaatat aaaattgctt
    23941 tatttacagg tgtttgtata gaaaaatata taaagttatt tattattatt tatatgacac
    24001 acccgattat tcaatattga gcaatatatc ccatgctctt atctctttct tttttgaata
    24061 aaaaatgagg taggacatct ttctgcccta cctcgtcttt aaataagctt tgatacttat
    24121 ttttcttcct tctcttctgt ctcttccagc gtttctgttg tttcagtttt tacttcaact
    24181 gtctcagctg gttcttctgt tgtttcaaca gtagtcgttg catcatttgt tacgacagtc
    24241 cctggtttga ccgttttgat tgctgcacga tcgtactcaa ggaagatccc ttcgcagtct
    24301 aaaacaactg tccgtttgtc attgtcgatt tctgaaacaa ctccatgtaa tccgccgatc
    24361 gttacgactg aatcacctgg tttcatgcta tctaacaagt tttgacgttc ttgctgttgt
    24421 ttcttttgcg aacgtgacat aaaaaaccac attgctaata gcgcgataaa catcacaagc
    24481 attggtaatg ttcccatttt tttcacctca ctaattctgt atctacaaaa aacactttag
    24541 cagaaaaatg ctgataacac tagtttttta cttaattttt aaaagatttt cctttagaag
    24601 ctttttgcgt tttctttatt gaacccgtat tcttcaaaaa aggcttctct aaattcaagc
    24661 aaattatcat ccatgattgc ttgacgtact tgtttcatta gattcaacaa gaagtataaa
    24721 ttgtggtaag aagtcaaacg aatcccaaat gtttcatcac atttgatcaa atggcggata
    24781 taggcacgtg tatagttttt acatgtataa caatcacatt tctcatcaat tggacggaaa
    24841 tcatgggcat atttcgcatt tttcactact agacggcctt gagaagtcat acatgtgcca
    24901 tttcgagcga ttcgagtagg caagacacag tcaaacatgt ctactccacg gataacacca
    24961 tcgatcaatg aatcagcagc accgacaccc atcaagtaac gtggtttgtt ttcggggatc
    25021 aacggtgtag tgaattctaa tacacgattc atttctgatt taggttcccc gacagataac
    25081 ccgccgattg agtaaccagg gaaatccatc ccgactagat ctttcgcgct ttgacgacga
    25141 agatcttcaa accctgctcc ttggatgatt ccaaataatc cttgacggtc tggattagca
    25201 tgagctttca atcctcgttc tgcccatcga gacgtacgtt ctactgattt tttcacgtag
    25261 tcgtaacttt catcgaatgg tggacattcg tcaaaactca tcatgatatc agagcccaat
    25321 ttattttgga tgttgattgc tttttctggt gataaaaaca tacgcgaacc gttcaagtga
    25381 tttttgaaat gcacgccttc ttcttcgata ttccgcatat cacttaatga aaaaacttga
    25441 aagccgcctg aatctgttaa aatcggttga tcccagttca taaatttatg cagtccgcca
    25501 gcttcttcta ctaagtcttc accagggcgt agccataaat gatatgtatt acttaaaata
    25561 acgccagcac ccatttcttt caactcttct ggggacattg tttttactgt agctaatgtt
    25621 cctactggca tgaacattgg tgtggggaaa gttccgtgtg gcgtgatcaa ttcccctaaa
    25681 cgcgcgccag tatgtttttc tttcttgatt aaacgatagc gaatggcagg ttgcgtcatt
    25741 catttcccta ctttctatat aaaatatctt gacaactccc accatcataa tcgtttcaag
    25801 tgctttttgc aagttccctc ggcttccttc tactttattt aatattcttt tttttatcct
    25861 ttttttatga ataacaaaaa aaagaaaaac attatgacag aaatattttt tgatacatgg
    25921 tatattggtg ttattaaaga aaaggaggga aaaatcatgc aatcttctgc agaattaaaa
    25981 cgccaagcaa aagagagtct aaaaggacgt tggggacaag ctgttttact aaatctaatc
    26041 cctacattga ttggtattgc tactattctt cttattatga ttcctattat cttgtttgcc
    26101 accaccatat atgatggatc agcgagcgtc tcagaagcga caacttcagg aggcggtagt
    26161 tcaggaggcg gtggcggaat tatttccagc atcattagcg ctttgttcat gagcggtatt
    26221 tcttggactt atcttgatat tttacgtgga caaaaagatc agatcgaacc attcaaagat
    26281 gcatttcgtg gattcaaagg tttgtttatc ggcggagtga tcagcttagc tgtgctgatc
    26341 tcgatcttta caacattatg gggtttgcta ttagttattc ctggaatcat taaaagctat
    26401 tcttattctc aaagctattt tatttactac gatatcgtcc aagaaacagg acaaacacct
    26461 aaagtactgg atacgatcac tgcaagtcga aaattgatgg atggttataa aggacaactt
    26521 ttctggttag atctttcatt tatcggctgg catatcttag cattagcaac tgctggtatt
    26581 ggttatctat ggctcagccc atacatttct gcaacaaaag cagcatttta tgaacaattg
    26641 ccaaaagata tttaaaagag agtgtgactt gtgaccgagg gggtggcagg agaacaccgt
    26701 ttatcgagag gcagtaaaag aaacattcag cccattagca aaaaggaggt gtgacaacat
    26761 tcatgtcaca cctccttttt gtatagttcc agtaaaaaga aaatcaactt agaaacagtt
    26821 aatcattcct cttcttctgc ttccggtaat cgatggaact tgatcagttc attcaccgcg
    26881 attggtacga tagataaaat ccctaccaag aaccagtgat tcaaactgat gtgtactagg
    26941 ccgaatagtt cttgcgtaaa tggcagcaaa gcaacagccg ttgtaatagc taatgccagt
    27001 aacgccattt ctaccaaagc tttattggtc gctaaattga ctttgaagat cgattggctg
    27061 ctgcgtacat tgaacacatg cagaatcgat gaataagcta agatcaagaa tgcaacagtt
    27121 tgaccgacat gctgacttgc gtctacccat gggctgatag tatcgacata actacctaaa
    27181 taataaccaa acaaggttac gatggtgaag acccctgcat ttatggcaat tttttgcaat
    27241 aaacctcgag caaagatccc ttcatttttc ggaatgggtg gctgatccat gatgccgtgt
    27301 tccgctggct ctcttcctaa agcaaatcct ggaagtccat cagcaactac attgacaaac
    27361 agtagttgca cagctgtaaa tggtgctccc catcctaaca gcatcgcaat caaaacaata
    27421 aagatctccg aaatattaca gcttagcaaa aagttgatag ctttacgaat attctgataa
    27481 accgaacgtc cttgactgac agcgtctacg atcgtcgcaa agttgtcatc cgtcaaaatc
    27541 atatctgcgg cactttgcgc cacatctgtt cctgtgatcc ccatggcaca cccaacgtta
    27601 cttgctttca acgctggtgc atcattcaca ccatccccag tcatcgctac gactgcaccc
    27661 gtacgttgcc aagatttgac gatccggatc ttgtcttctg gcgttacccg agcatagaca
    27721 gagagagctt tgacacgcgc atctaattct tcgtctgata attgatgcag ttctgatcct
    27781 gaaagtgctt ctgacggatc attcaagata cctaattctt tcgctatggc actggcagtc
    27841 accacatgat ctccagtgat catgactgtt ttgatgccag cctttttcgc tcgcttgatt
    27901 gctcctttac tttctggacg tggtggatcg atcattccga tcagaccaat caaacgtaag
    27961 tctttttcca gtgcttcaga agaaatatct tgcggttctt cgtcataagt agcataacca
    28021 acagcaatca ctctcagtgc ccgtttacca aagcgatcat taacgatcgc cgcttgttct
    28081 acatcgcctg aactaaagcg cggagcaaga acatcgaatg ctcctttggt gattgagatg
    28141 tatttttcgc ccatttggtg aactgttgtc atcatttttc gttcagaatc aaaaggaagc
    28201 tcgtttactc gtggatattt ttcttctaat tctgcctttg tatgataatt ctcttcaaca
    28261 gcccttacga tggctacttc tgttggatta cctttgataa caaggtcgtc atcttcttgc
    28321 tcgaccgtca catctgtaca tagtgcagcc attttcaata tttccatcgc gctgttcgtc
    28381 attgaatctt cgatattcgt tacttcatct tctttgctcc atacccggcg gacgcgcatt
    28441 tcattttgtg tcagcgttcc tgttttgtct gagcagataa cattagcggt tcctagcgtt
    28501 tcaactgctg gcaactgtcg gatgatcgca tgtttcctcg ccatcttctg cacaccgtat
    28561 gcaagtgtca acgtaacaat aacagtcaag gtttccggta cagctgcaac agccaaggaa
    28621 atcgaagtca tgaacatctc aaggagtggt tctccttgca gttcaccaat cacaaatact
    28681 aaagccgcag ccgctaaagc gatcatactg attcgtttgc ctagctgatt caatcggacc
    28741 tgtaaaggtg ttttttgcat agtattttcg ttcaaaagat ccgcgatctt acccatttct
    28801 gtagccatgc caatggcagt gacgatcgct ttcccacgac ctgcagcaac cgtacatcct
    28861 ttaaatacca tattaagttg gtcacctaat gactcatctt cttcagcaat aaatgctgca
    28921 tctttttcaa ctgcttcact ttctccagtc aacgccgatt cttctacacg taattgtgat
    28981 gcttcgatca aacgggcatc ggcagaaata gcatcaccgg actctaaaac aagaatatca
    29041 cccactacca gttgctctga ctcaacagtg gtcactttgc cgtctcgtat gacagttgcc
    29101 gtttgtttat tcatatcttg caaggattcc agtgcttttt ctgcgtttcc ttcttggaca
    29161 atcgccaata ccgagttgat cacaacgata gcgatgatca gcagtccttc aaataaatcc
    29221 ccatgttctg tagcaaatgc ggtataaaag gaaatcaccg ctgctacaag aaggatgatc
    29281 gttgtaaaat cggacaagct tcgaaagaat tttttgatca tcgattcttt cggcgcctca
    29341 tcgaatttat tcaatccctg cttttttcgc cgttcatcca cttcttgtga agacaaccca
    29401 gtatctggat ctgcttctgt taccttcttt acttcttcta ttgtctgctt gtattcttcc
    29461 atcctattcc tcctttaaaa tcttcgtaca aaaaaaggta cttattttac tataacatcc
    29521 tttttttatt tacttcaaat aaagggctta tcgattattt gttaagaaag cgtaaaattt
    29581 aaagtgctta tatttgcaaa cgctaccaaa ggatgctatt atatagatgt aaggaaggag
    29641 gataccatca aatagacaga agaatttctc gatagaacag tgtaagcaaa caaagttgtt
    29701 agaagtacag gtttcaccca gacatgcgtg tagagtacaa acctataaat agtgaatgcg
    29761 tatggatgtt tggatcacga agtatccgaa acaagaagta atgcgatacg taacaattga
    29821 ataacgtaaa cgtctgaaaa ttgaatagga acaagagatg tttcaaatgt tgaagatgta
    29881 acgaaaacaa aatttttgtt taacatgaag aaattcaaca ccgtgctttg catgtatgat
    29941 ggaaagttac aatcatttct gtttatttga atccttccga ggtacaagaa agccgagctt
    30001 atcgagagct cggctttttc tttgtcataa aatctttgta aagctttttt gttattcaaa
    30061 actagcggct tttcataacc ttatttcacg aacatcgcat ctccaaaact aaagaaacga
    30121 tagcgctctt caatcgcatg ctggtaagca gataaagtca attctcttcc tgcaaaggca
    30181 ctaactaaca tgactaaagt cgattttggc aaatggaaat tagttgagaa agcttctacc
    30241 actttgaatt catagccagg cgtaatgaaa atatcagtcc atccgctgtc tgctttgatt
    30301 tctccattaa atttcgttcc aatcgtttct aatgttcgaa ttgaagttgt tccgacagcc
    30361 acgattttcc cgccattttt acgtacttgg ttcaatcgct cagccgcttc ttccgtcaaa
    30421 cggtagaatt cactatgcat atggtgttct tcaattttat ctacgctgac aggtcggaat
    30481 gtacctaacc ctacatgtag tgtcagatag actaattcaa caccctttgc ttcgatctca
    30541 tcaagtaatt ctttcgtaaa atgcaatcca gctgttggcg ctgcagcaga accattttct
    30601 ttcgcataga cagtttgata gcgatctggg tcttccagac gttctttgat atatggaggc
    30661 aatggcattt ctcccaatga ttcaagaatc tctagaaaaa ttccttcata ctcaaagtca
    30721 atgatccgtc cgccgtgttc caattcttct ttcactactg cttgcaatct gccatcacca
    30781 aaagagattc ttgtcccaac tttggcacgt ttcgcaggtt tgatcaatgt ctcccacgta
    30841 tctccttgtg tattcgttag aagaaggact tctaaatgcg caccagtatc tggtttttct
    30901 ccatataaac gagcaggcag aactcgtgta ttattcataa ctagcgcatc accaggctgt
    30961 aactcttcaa tgatttcatg gaaatgttta tcttccatct ctccagtttt ccgatccaaa
    31021 acaagtaaac gagaatgatc gcggtctttt aatggtgttt gtgcgattaa ttcttccggc
    31081 aagtcaaaat caaaatcttc tgttgttaac atatcgtcac tcactttcta tcatgtgctt
    31141 catcattcta tcatgttttt cgttctgttg gcaaaatcag cactttttca cttctatttt
    31201 ttgttttcct aaataaaaaa actaccctat ttgtattttt tcattgtttt aggcatacta
    31261 gtaatagata gttcttcatt gaaaatagaa aaagaggtgg caccatgatt gaatttcaaa
    31321 atgtgtcaaa aatttataaa ggtggaaaag tcgctgtaga ggacgtcaat ctttcatttg
    31381 aaaagggtga gttcatttgt tttatcggta cgagcggaag cggaaaaacg acgacgatgc
    31441 ggatgatcaa ccgaatgact gatccaacac aagggaaaat tttgattgat ggaaaatcca
    31501 tccaagaaat tgatccagtg gaattgcgac gtcagatcgg ctatgttatc caaagtattg
    31561 gattgatgcc tcacatgacg atccgtgaaa atatcactct tgtccaaaaa ttgttgaaag
    31621 tcagtcaaga agaacggaat aaaacagctg aaaaaatgat tgatcttgtg gaattgcccc
    31681 gtgagatgtt agatcgctac ccacatgaat tatctggtgg tcagcagcag cgtattggag
    31741 tcgttcgtgc ccttgcagcg aatcaagata tcatcttgat ggacgagcca ttcggtgcgc
    31801 ttgatccaat cactcgtgat tccttgcaag accttgtcaa agatttacaa gagcgtttgg
    31861 gaaaaacgat cgtatttgta acccatgaca tggatgaagc gattaaacta gcaagccgta
    31921 tcgccatcat gagtgaaggc cgtgtgatcc aatttgatac accagaaaat attttacgtc
    31981 atcctgcaaa cgatttcgta gaagagttga ttggagaaga tcgcctacta caagccaagc
    32041 caaatgcgac aagagtcggc gaagttatgc taaatacagc aatcacgatt acaccggaaa
    32101 aatcattaca agaagcaatc aaactgatga gggaaaaacg tgtagatacg ttgttagtta
    32161 ccgataattc gaatgtatta aaaggattta tcgatgtaga aacgttgaat aaaaaacgag
    32221 gaaaagtatc cagtgtcggc gacattttga ataaacatgt tttttacgta aaagaatccg
    32281 cctatcttcg tgataccttg caacgcattt taaaacgcgg gctgaaatac gtgccggtcg
    32341 ttgatgaaca gaacaaagtc gtaggtatcc tgactcgtgc atcattagtg gatatcgtct
    32401 acgatgtgat ttggggagaa gatcccgcaa ctactgatgt tgcagagtca gctactcctg
    32461 aagaatctaa ggaggtctga cctatgcagc agttttttca tcagcacggt tcagaaattc
    32521 tctcaaaagg ttttgaacat ctttatattt caggacttgc tttgatcatt ggtatcatca
    32581 ttgctgtacc gcttggtgtc ttactgacac gttttccaaa agctgccacg attgtgattg
    32641 gcttaaccag tgccttgcag acaatccctt ctcttgcttt attggcattg atgatcccgc
    32701 tatttggcgt aggtaaatta cctgcgatta tcgcactctt tatttattca ttattgccga
    32761 ttttacgtaa tacgtacatt gggatgaaaa atgtcgattg gaattatcgg gatgtggcaa
    32821 aaggcatggg gatgactgag ttccaatcca ttttttccgt tgaattgccc attgctatgc
    32881 caacgatcat ggctggtatt cgtttagctg ccgtttacgt gattgcatgg gctacacttg
    32941 cctcttatat cggcgctggt ggtttaggcg atttgatttt tagtggactg aataattacc
    33001 aaccagatct cattttggca ggtacgatcc ctgtaacaat tttagcacta ttggctgatt
    33061 ggcttctagg tctcttggaa caccggctga caccgatcgc acttagagag gagaatgaag
    33121 aatgaaacgt atactaaaaa tgaccatggt tcttttctct cttcttatac ttgcgagttg
    33181 ttccttccct ggtcttgcca gcaatacaga tgaagacacc atttcgatca caggtggaat
    33241 cacttcagaa gcacagatct tagcaagtct agttgccgga atggttgaac attatacaga
    33301 taaaaatacc gcaatcatca acaatctggc tactacaact atcaaccatc aagcgatgat
    33361 gaacggagat gcttcaattt cagcggctcg ctacacagga acagatttaa cgactacatt
    33421 gaaccttcct cctgaaaaag atccgaaaaa agcgtttgct accgtgaaag atgaatttga
    33481 gaaaagatac ggtcaaacgt ggttcccgtc ctatagtttt gaaaatacgt atgtctttct
    33541 tgttcgaaaa gacaccgcac aaaaatacca tctatctaaa gtcagcgatc tgaaaaatgt
    33601 agcggatgaa ttagtagctg gtgtagatac ttcttggatc aatcgtaaag gagacggtta
    33661 tgacggcttc caagaaactt atggcttctc cttcaattcg atattaccta tgcagattgg
    33721 acttgtttat gacgcagtcg aagcaggaaa aatggatatt gttcttggct actctacgga
    33781 tggacggatc gccagttatg atctagtcat gttggaagat gatcgtcaat tcttcccacc
    33841 atatgatgct gctccagttg tagacaacaa gatattagct gatacgcctc atttaaaaga
    33901 agccttaaat aagttaggtc ataccatcag tacggaaaaa atgcaggaat tgaactacga
    33961 agcagataat aatctagtgg aaccatcagt agtagcacaa cgtttcttac aagaaaacca
    34021 ctattttgaa gggaagtgaa gcaattggat aaaatgaatg tctttcaaca atttttctat
    34081 tatttccagg aaaatggctc ctatatcttt gcacaattta tccgtcactt cctgatttct
    34141 atctatggtg tcctctttgc agcagttgtc gggattccgg ttgggatcat gatttctagg
    34201 agacgtaaat tagcaaactg ggtgattcgt ttggcgaata tcatccagac gatcccttct
    34261 ctagccatga tctccatttt aatcattgga ttaggcctgg gagtcaatgt cgtgattgtt
    34321 actgtatttt tgtattccct cttaccgatc atcaagaata cgtataccgg gatgatccaa
    34381 gtagacaaaa acatccttga tgtcggcaaa ggcatgggga tgactgctag acaacgacta
    34441 ttcatggtag agttaccact ctctgtttct gttatcatgg caggcataag aaacgcgtta
    34501 gttgttgcca tcgggataac cgcgatcggt gcattcgtcg gtgctggtgg tcttggagat
    34561 atcattatcc gaggaaccaa tgcaacagag ggcacatcga ttattttagc aggtgcattg
    34621 ccaactgcat taatggcgat catcacggac tggcttttag gtattttgga aagacggcta
    34681 gatccagcca gccgtacatc acgctgatgt tattgtaaaa aacaaaagct tctgcgacca
    34741 tttgttggtc gcaaaggctt ttttagttct gtcattttta aggcaataat ccactctgat
    34801 tcttccctcc ttatgggtaa agagttgctt ttcttagcta tttatccatt ccgtatactc
    34861 caacttcata ctgccaacgg gttcatatct gcatccaccg actaagtttt tttcttatcc
    34921 gctaaggcat tttgccaatc cattttccca tcactcgtca tggaattcat accacatgat
    34981 ctctaaatac tcgtctgctt gttctttgaa ttgggcatca attcttacat cctttggcgt
    35041 ggctttcatt taagcctttt ccatcagtcc tcgattgttc gatgccttca gctgcatcat
    35101 caaaactggt gactgccgta tcggtaactt cgatcatctt ttatacaatc gggaacttgc
    35161 catcctcatc cttggctaaa aacatatcta gccattccag cttctcgcca tgggaggttt
    35221 gcggttccta aaaccggtac acgattctta tggactgcat ccgtcgcaac tagacttggc
    35281 gatacgatga tccttcacca gaagagcacc cccgtaaacc aattgatcga tatattgcca
    35341 ataagaaaag acattggcgt aaaagatatc gatccctcgt gatgcattgc cgttgatact
    35401 gctattcatg gccgaaagcg ccacgacttt aacttcttcc gtttgagtga cattcatgtt
    35461 cggcaatgtc gctttggata cccgctctgc taaaggaacg acactggtat tgtatttcgt
    35521 atctgtatct tttccaaaag accatgccaa cgaatcctct gggaaccaat aagacgactc
    35581 cggttgattg tccattgctt ttttcaacat acttttggct gtttctcgat aaacgacatt
    35641 tccaattgtc ttcgcctcac tttggcgata atcgatggtc gttgccactg ccaacactaa
    35701 caacgatgct ccaattttac tgattttcct tgtcacactt cttcctcctt gttttacata
    35761 aacccgtcaa cattccattc ctaaactcaa acaatgaccc ttcaaaggtg gagatatagg
    35821 aacaaattaa agaaatcatg caataaatcc aagaaggttg gttttagaac aaaaaaagag
    35881 tctccttttt ggggagactc tttgttaact atctaaaaag gttggctctt ctcacttcac
    35941 tcataatgtg tccaggcaga ataaatttct acaactttat tttcctcatc aactttgtaa
    36001 accactcgat gctgtctatt cagcctgcgt gagtatctgc cttcatgtgt aggtctcagc
    36061 ttttcaaaag actgcgtggg catatatgga tcttccttca atgtctgaat cacttcttca
    36121 aattgtttct ttaaattcgt ttgcttgatt tttcttaaat ccactttcgc agagtttttg
    36181 attgcgactg tatagttact catcaaagag cttcccaatc aatatcatcg atattcgtaa
    36241 agctactgtc gtctttttcg cggtctcgta ctttatctaa agtacctgtt tgctcaagaa
    36301 aaagggtttc ttgaatcgct ctccagtctt ccagcccaat caatacagca ttgtttccac
    36361 tacgatcact aataatctcg atttcagtat gattttcatt tacctctttc aataactgat
    36421 aaaaattttt acgagcagtg ctaggattca tcgttgtatt agccattgtc tctcctcctt
    36481 tttctgatat aattatagcg tacttgatta agtacgtcaa aaaaatacaa taaagcactt
    36541 aaattcagca aacttttcct cttttttaca tagagaaaaa gacccctttt tagggaggat
    36601 ctttgtccac gctcacttct tactccttta cgactagcgg tagccaaacg taaagtaatt
    36661 ggtaacaacg tatcatcttt agcaaaggtc gaatccaaag cctgtgagtc tatgcaacaa
    36721 caccaataca cgaaggttcc tcgttgcagt gtgacttgat tgatatcttg aataacctga
    36781 ggatacgcac gaaagatttg taacggttat tcaaaactga ttttggccgt caagtcttct
    36841 actgcctcaa aaatgattgc ctctttcgtc tcctgtcatt catgttcact atcgatttga
    36901 tacttgctta gaccgttggg tttgtgaatc accaattaaa aatggcactg agttatggta
    36961 acaaaaaatg gtcacttgac gaggctgaga ttcctactta tgaagacaca tggcacttaa
    37021 gagtcgaggt aaaggaagaa gctgaaaata taggaggctg tacattattt ggcaaaggat
    37081 tcggaaatta tgatcaagac atcaaaatca aaatgtttta cagctaaata ggaagaataa
    37141 taacatttca tacgctgttc ccatctttaa tggcttatag agggcacctt tagctgagaa
    37201 taagacaaaa cagaccctct agcttcaatt aagagctaga gggtctgttt ttgattttaa
    37261 aacttggttt atttcttcaa atggtagcta taggtgctga caacgatatt ttcacgccaa
    37321 gacaatcgca atcttaaccg caaacttgtt tggttatgga gaatattctg ccagcgtctg
    37381 tttggtacaa attgaggaat caacacagta gttgtatagt tttgtttcgc tgcattttta
    37441 cttacgatat ctacataacg gataattgga ttttcaatcg agcgataaga agagtggacg
    37501 attgaaaaac ggacatctgg gaaatgcttt ttaaattctg cttcgatttc tttttctttt
    37561 tcgacatctt cgtctagcga aacatgcatc gcaacgacat aatcaccgat cgaacgtgcg
    37621 taattcaacg caccgatatt tacccgtgtc acattcccga ctaatacaag aacggtattc
    37681 ccgtcataat catgtagttt tgcatcattt tctaaacgaa gctgttctgc tactttttta
    37741 taatgatcat ggatcttata aaaaatgaac ataacgattg gcataatgat gaagaaaggc
    37801 caaatgtccc ctaaccgata gacaaacaaa atcgcaatga ttgcatatga gatgaacgca
    37861 cccgtaatat tggcaatcga tttgcttaac catctttttc cttctttttt ccatttgacg
    37921 accatccctg tttgagataa agcaaatgga atgaacacgc cgatagagta taacggaatc
    37981 aagcgttctg ttgagccatg gaaaataaac agcaatacga tcgaacctag cgctagtgtg
    38041 ataatcccat tggaatagcc tagtcgatcc ccacgatctt gatacatgtg aggcatgaat
    38101 ttatcttttg ccagattgta tgcaagaact ggaaaagcag aaaaaccggt gttagcagca
    38161 actgctaaaa tcagcgctgt agcaaattga aggacgtaat acaaaatacc atgtccaaag
    38221 acagctttac caatttgaga caaaacagtg acttcttttt caggaacgat cccataccaa
    38281 tagttgataa atgtgatccc cacgaagaag aaacctaaga tcaatgccat catcgtcaat
    38341 gtagcagcgg cattttttgc tcttggcttc ttaaagaatg gtacagcatt actaatcgcc
    38401 tccaccccag ttaaagagga agaaccagaa gaaaatgctc gtaaaatcaa agcgatagaa
    38461 acacccggca cagccgctcc tggaagtgca gtagcttgca atggcacagc acctgtcacg
    38521 atattatata aaccaacaac gatcagtaac gagatcacaa ggataaatgt gtacaccgga
    38581 aataatagga acgatgcaga ttccctcagc ccacgaagat tcagcatcat cagtagcaaa
    38641 acgattgtca cagaaatagc gacttgatga ccgtagagtg ctggcaccgc tgatgtgatc
    38701 gcttcagcac ctgctgagac agatactgct actgtcaaca tgtagtcgat caataaagag
    38761 ccaccggaaa tcaagccagc attctttcca agattctcac tgctgacgac atatgctccc
    38821 ccgccatgag gataagcatg gatgatttga cgatatgata gcgttaatga aatcaataaa
    38881 ataataacaa aagcggcaat gggtagcgaa taccagatgg ctgcagcaga caaagcgact
    38941 aaaacgacaa cgatttgttc cgtaccatat gcaatagatg ataacgcatc agacgacaat
    39001 aatgccaaag cagcaaatcg ggttaatttg tgctcatcat tttcagcaga ttttaaaggc
    39061 ttacctacta acaacctttt taagtaatcc aatttctaaa ctcctttaca cacaatttta
    39121 cttcaagttt tatagtcgaa aatttatagt aaacaagatg ttatagtacg ctcactgacc
    39181 ttaaaagtca ataaacttta agaaaataat tggaaaaaaa cagaaaaata tcaagcgctt
    39241 tttcaaacgc tttaatacag caaaaatcta acattttttt atgggctttt tctttgaatt
    39301 ctataataaa aggatagaac ttgacttaga aaatcaagtt ctatcctttt tgatatctta
    39361 acttttggaa gagagatgta aggctgcttt ctacccatca ttcttactac tcgaagcata
    39421 gcgcagttgt cacaacctct tgataaacgg tgtttaaaag cttgcatctg cggtaataag
    39481 cccaaccaaa ttaaaaacat aagaagctgt ttttatttgg tcgttcttat tacttgatgc
    39541 agagcagctt ttttacaacc tcttggtaca cggtgttcaa tcagctgacc ctcggtatta
    39601 gctcaaaaaa acggcaaaat atgaggaact atttttccat ttttttctct aatactcagg
    39661 tcaaaacact gatttcacaa cctctttttt taatgaaaaa tatggctctc atgcgccgct
    39721 tctttgaatt tcgtcatttt ttcttcgatg aacggataga ttgccgttcc tacgattcca
    39781 aagacaacaa acaaaccgat catgatccag attgctttcg tagcatttgg ccaataaatt
    39841 cctcctgcag attcccgtaa caagtttacc gcatgagtaa atggcaagaa cggattgatc
    39901 atttggaaga atttccctga gacttggatc ggatagttcc cgcctccgcc agagatcgac
    39961 agtactaaga tgataatagc gatcccttta ccgacattat cgaataatgc agccaagaca
    40021 tagacgatca tcatgaacgc taaggcgatc aagacagcaa atgacacgct gtagaccgga
    40081 ttttggacat ctactcctag taagaaaata ttccctaatg taacgatcaa gctttgcgca
    40141 atcgccattg tcaaaaatgt cagcatacga gcaacgaatt gttctcgttt cgtaaaattg
    40201 tttcggtctt tctttcctaa atagtattct gtcgtagcaa cacttgaaag aagaacagcg
    40261 ccgacccaca gacatagtgc agtataaaac ggggtgctag ctgaaccgtt atttgcgatt
    40321 ggataaagcg cattggtttg tagctcaaca ggttgtgtaa agaagtcact ttcttttgtt
    40381 gcgtctagtt tcaataattt gatgacttcg cctagatcga cttcttgttc gccttttcgg
    40441 atcgcgtctg ctgctttttg gataccagct ttgatatttg gccagtcatt gttgatcaag
    40501 tccgcagcag cgttcacagc tgtttcgact tctggcattt tttcatttac tgttgtcaat
    40561 gtaccggtga tttcattttt tagtgctggc caatcatttt ggataaaatc agcggccaat
    40621 cctaattttt gctgaatgat cggtaattca ttgttgtata ggtctgcccc ttcattgatg
    40681 ccattgacga tggtatccat atttccattc agcattgtat tggcatcatg gatttcttgt
    40741 ccaattgcag gcatttcttt ttgatatttt tctaaaattg ccactgcatt cgttacagtt
    40801 gctttcgttg agctgagaag cgaatcaaag tcgatctggt ccgctttgct cagtgcgcct
    40861 tgtgcagtcc caatcgtatc gatgacttgg tctagtagag aagtgacagt ggaactgatt
    40921 tgacctgtat tgataccagc aatgatgcca ttgatattat taacaacggc atcaatttga
    40981 tctagcaatt catcaatagc cttcgtgtct tcattttgaa cagctgtgtt caaagcagat
    41041 aggcggtttt gcagattgct tagcaagggt tttaattgat ttagctgatc aataattggc
    41101 tgtaatttcg tatttccagc acttgtttgc aatttagtca ggaactcgac cagtttatcg
    41161 attgcatttt gttgttgaga tattccgtca ataaagccgt tcaatacatt gctgatgttt
    41221 ttcttttcat catcagtcag cttaccatct tcaatagctg ttcttacagt atctattaac
    41281 gaacctgtcg ttgttgccac ttgtccaatt gacttcaatg taacatctac actgtttgtg
    41341 atgcttggta tcgcatcttt cagctgagag gcacctgatt ttgtttggtt tgctagatca
    41401 cttgcctgat tttctaaatt tttcacatct ggcaagatat cttgtacttg ttggatgatc
    41461 gtcaagcctt gttttgcttc atcgattcct tggttcattg tctcttggat cgaagcaaaa
    41521 tcgccgtcga tctctgctag ttgcttaccg gcattttgga tctctgggat tttttcttgc
    41581 aaatcaagga tgatttttgc ttgatctttc aactcaggca ttttgtcatt caatgcaacg
    41641 actttttcac ccatctcatc tactttaggg atgtaatcca cgaattcatt tgctttattc
    41701 agtttttcct tgatttcagg tagttgactt tgtaattcga ggacttgttt tgtgtagccg
    41761 tcgatcgtgt ccaaattttc atctgttgat aaaatcatat ctttaacttt attgatactt
    41821 actaggttcg tatcgatgtc gtaacctatc tcattgaata ctttcaataa agtcgaactg
    41881 gctgttttga taaattcatt tgtgatttgc gattggatcg aacttgctcc tttatcggtg
    41941 attttcggtg caatcgcatt gattttttca tttaccgtat attcgatttt tggtttcttg
    42001 atatcaccac tagtaaaact cagcagatct tctgagaaat cctttggcaa gtaaatacct
    42061 gcgtaatact ttccggaacg gactccgtct tctaattgtt cttttgaatc aacgaattgc
    42121 catcctaatt gtttattttt atgaagcgat tcgatgactt gctccccaat ggccacttct
    42181 ttaccttgaa actctgctgg cttgtctgca ctgtaaacag caattggcag ctctccagta
    42241 tttccatatg gatcccataa tgctttgatg ttaaaccacg catatagcga agggatgatc
    42301 atgatcgcga tgatcagaag tgttgcaatc gggtttttga aaatccgttt ccagtcaagc
    42361 aaatataatc gaagcgtatt tttgattgac tgcatagttc tcccccttct tcttttttca
    42421 gctgaattac tttaccatgt atttcatact tttttcaatc ggcttttttc aaaaaagtcg
    42481 aatttttgga catatcacgg caattgtctc attgtaatct cttacatatt gagaaataat
    42541 taaggattac agcctttact ttatcatgaa ataaaaggga aagataattt tatgccaaag
    42601 tttttatcta ttatacgtat acgcaaaaaa gctaaaacat tttttgtctt tgcccctaca
    42661 aaaatgtttc agcttttttc gttttttatt cctgtatttc ttatttttcg aatgacagga
    42721 tgattttccc agcaggagga tgtccttcaa ctagctgatg tgcttggatg acatgcttaa
    42781 gtgaagcaga cagattcatt gaaataaaaa catgaaaggc tcctttttgg taggctttga
    42841 ttatgccagc aaaggcttct gcatctagat attcctttct tggaacaaac gattcataaa
    42901 agccttcctt tttttgccgc aaatctagat ctgggaggtc atttaatgca acatacctgc
    42961 cgcctggttt catgatctgg atgccggttt ctcctttgat acttcctttc gtcgcatcga
    43021 ttacaaggtc tgcctgatca gcaaattgca gacctggatt tgttttatca taagcagcaa
    43081 atgctgaagc tcctaatttt tttacctttt cctcattttt actggatgca ctggttaaga
    43141 ttcggattcc cttttcatgg agaagctgga tcagacttga cccgaccgca cctgatgctc
    43201 ctagtatcat tacagtatct gtcggctgga tttccgtcaa atggttgatt agattataag
    43261 ccgtaattcc tggcgtgacc attccggctg cttcttccca actcatttta tctggaattt
    43321 ttgctacttt tgctgatggc aacacgactt cttctccgta agtcccgccg actgcatgga
    43381 cagctactcg atcacctaca tgaacagttg tgacatctga accaatctct gtcacaatac
    43441 cagcgccatc attacctggt acataaggga atttcaatgt tcgtatctct ttcatttctc
    43501 ctaaacgcaa ggcaacatca taaggattca cactgaatgc ttttatttct acacgaacat
    43561 gtccagaacc gacttctctg ggatgagcat cgatttcttc aaaaacatct tgtgcttctc
    43621 cgtaaccgtt aattgcaaat cttcgcatgg tcaccatctc cctttttctt taagtttacg
    43681 tttatgcctt tattttgaca aaaaaaatgt cttttcgttt tggcgcatga ttcaaaacaa
    43741 aatagttgtc ttttttcgcg taacgtgtta aattatttat ctaaaagcgt aaagattacg
    43801 atttacgcta ataaaaaata attggaggaa tttgttgatg gctaaaaaat caaagattgc
    43861 caaagcaaaa aaacagcaag aaacgattga acgctatgct gctttacgcc aggaattaaa
    43921 agcgcaaaaa gattacgaag gcttgcgtaa acttccttta gatgctcgtc cagaacgatt
    43981 gaaaaatcgt gatttaatcg atggacgccc tcgcggatac atgcgtaaat tcgggatgtc
    44041 ccgtataaaa ttccgtgaat tagcacataa aggtttgatt ccaggagtaa aaaaagccag
    44101 ctggtaatcc aagtctggct gtaatgtaaa ggaggagggc gcatggacca ctccttggat
    44161 catcaaaaaa gatacgttcg cttcttctag cagaaatgct ggtactagaa gcagacgtat
    44221 ctttttttac gcacagctgg tcctttttta tatgtaaagg ctgcatggtt acttcgctat
    44281 atttatttag taacaggagt cagtgcttcg atacccacac taattttcaa tgctcggtca
    44341 acttctgcca taatgggtcg atccaaatgg cagacctttt ctttcaatct tgatttatcg
    44401 atcgttctga tctgctccaa caggataacg gagtctcttt ctattcctgt tccagtagct
    44461 ttgatcccaa tgtgagtcgg aagcttaggt ttagccattt ttgccgttat ggccgcaaca
    44521 atgatcgtcg ggctaaaatg gttacctaga ttattttgaa taaccaaaac tgggcgtgtt
    44581 ccgccttgct ccgatcccac gactggagaa agatcagcaa aataaatatc tcctcttttt
    44641 accataggat cctccttatt cttgatattc tcttggtatc cgctgtccta atccgcaagc
    44701 cacttcatag tggatcgtac ctaattgatc tgctatatcc tgcatagtga tttctttgtc
    44761 tgcatttttg ccgataagcg tcacttttgt tccgacagga aattcttgag gcaatcggat
    44821 catcagttga tccatacata cacgcccaat cgtttcacag tagttccctt ctaccaatag
    44881 agaaaaaccc tgcatctttc gtggccagcc atctgcataa ccgatcggta tcgttccgat
    44941 ccactctgct tcaggagtga tatatgtttc tccatagccg attccttcac ctgctgggag
    45001 ttttttgact tgaatcaatt cagaaaccag ctcaagtgct ggctgcaatg gataaacttc
    45061 cggtagtgcg tgcccagagg gattaagtcc gtacattgct actccataac gaatcatatt
    45121 gccgattgtt tcatcatgcc ataaagccgt tgcactattg ctgacatgta catatcgagg
    45181 aagttcggga agttttttca gcacttctat aaagcgttct ttttgcagat tccaatatgt
    45241 atcatctgcc tgatctgctg tagaaaaatg ggtaaataaa ccttcccatt ctaatacacg
    45301 actttctttg atgaatgcag ctgcctcttt tacttcttca ggtgtacaaa atccgatacg
    45361 acccatccca gtgtctgctt ttagatgaat cgaaagaggc gtctctagct tacttttctc
    45421 taaaacagca gctgctgctt gcaaccattc ccgtgtacct gcagttactg ataaatcatg
    45481 agcaacagct acagtcagtg cgtcgtaagg aaccatattc aagataagga tgggctgagt
    45541 aaatccagct tctctcaact cgactccttc atctaaattt gaaacacaaa agcccgaagc
    45601 tccacctgca actgctgcct cagctgtttc aatagctcca tgaccgtatc cgttcgcttt
    45661 tactactgca aacaattctt ttccttgcgg aagtcttgca acttcatttg ctacattttc
    45721 agttatagct tttttatgta tcactgcttt cgttgggcgg tgccaagcga caaccatcgt
    45781 ttttccttct ttctagtctt ccaaaataat ttgtgcaaaa gctgtttcat ttgtatgagt
    45841 aatactgacc catacattgc cttcatgagg tgaacgcgtc acaacaggct gaccattttc
    45901 attttttaaa atctcgacat cttgaaaggt aacttttccg atcccagttc cccaagcttt
    45961 agagaaagcc tctttgcaag cgtaacgccc gcctaaaaat tctacttggc gatgaaaagg
    46021 caaggactgg aatagtttca tttcatcaga ggtcaagatt cgtgcaatga attttggttt
    46081 ttcttcgatc agccgagtga tcctaggaag ttcgactgca tcgatcccaa ttccttttat
    46141 catatgcttt tctcttttca ataaatttag aacactctca ttctaccaaa ttataaccat
    46201 tttgccacaa ataagtccac aaataacaaa aatgaaagtt tctcttaaaa aagagaaact
    46261 ttcattttat gtttaatcgt tatttgaacg gattacaaat ccgcgttttt tatcattgtg
    46321 acgtttaccg ccatcttttt ggctgttatt atttttgcta taaccgcctt ttgatttgtt
    46381 tccacgataa ttaccgccgt cacgacgatt acggttgttt ccgccaccac gtttgccatt
    46441 tttattgtat ccttttttct gcattggcaa tgggcgttct ggtgtgatct tcactggcac
    46501 tgcatcagct ggatcttttg ctgtcgtttt tagcaaaagt gcaactaaat cttgtgcaga
    46561 atattcttct aataatttat ctgctgtttg caggtattta tctagaccat tttctgcaag
    46621 ttttgtttcg atttgttcaa ctgcagcacc taattgacct ttgaatgctt ctttttcggt
    46681 tggtggacgt aaagtcgtca tccgtttttt cgtcaagttt tcaatcacat gcaagtagtc
    46741 catttcattt ggtgtaacga aagtcacaga cataccgcct tttccggcac ggcctgtacg
    46801 tccgatacgg tgaacgtagc tttctggatc ttgagggata tcatagttgt acacatgagt
    46861 gacacctgaa atatctaatc cacgtgcagc aacgtctgtc gctacaagga tatctaaatg
    46921 accgctctta aatgaacgca atacgctcat tcgtttttgt tgagacaaat cgccatggat
    46981 tccttctgca cggtaaccgc gtgcttctaa tccgcgtgcc aattcgtcta cacggcgttt
    47041 tgtacgtccg aagacgattg ttaattcagg tgtttgaaca tcaaacaagc gagtcatgat
    47101 atcgaatttt tcgtattctt ttgcgcggac atagtattga tcgatcaagt cagctgtcat
    47161 ttctttcgct ttgatcttca catgatgtgg atttttcatg aatttaacgc caatattctt
    47221 gatagctggc ggcatcgttg ctgagaaaag taatgtttgt ctttgatcag gaacttgtga
    47281 aatgattttt tcgatatctt ccaagaagcc catattcaac atttcatctg cttcatccaa
    47341 aactaatgtt tgaacggttc caagtttcaa tgtgtggcgg ttaatgtggt caagcatacg
    47401 tcctggtgta cccacaacga tatgtggacg atctttcaag ccacggatct gacggccaat
    47461 atctgctccg ccgtaaacgg cttgtacacg tacttttttg tcgcgcccta aacgatataa
    47521 ttcttcttgt gtttggatag ctaattcacg tgttggtgcg ataactaaac cttgtaattc
    47581 gtgacgatct ggatcgattt tttctaacat tggtaatcca aatgcagctg ttttccctgt
    47641 acctgtctgt gcttgtccaa taacgtcttt tccagctaat gctagtggaa tcgtttctgc
    47701 ttggataggc gttgcttctt caaaaccagc gcgttcgact gatttcaaca attctggtga
    47761 taattctagt tctttaaatt tcaaatgaat cctcctatat ggttgttaac tgaggatgta
    47821 gcttttttgc taccccgtcg atttgttcgg tcaaagtgta ttgtttcttt ttgacagtgg
    47881 ccacgcacgt ttttatccat tcttagcccc tgtggcacca ccgaaaaatc actttgcgaa
    47941 gtttaggcat tagaaaagcc aaacgggtcg cgttcagctt tatcattatt atgacatctg
    48001 gcttcaacaa gttgtttcta tggcaaaacc agtccaattt ctcttcatct ttcggcaata
    48061 ggttattcta acatagtttt tcgttttctg caagtttaca gatttttatt tcatttgctg
    48121 aagttgttct accacttcaa ataagcccat gctgttgctg ccttttagca taatactatc
    48181 tgttgcttca agattttgtt tgatagcatc aatcaattta ttcttttctt tttcaaaata
    48241 gaacacaggt agttgggggt atttttggtt caattcttct tttagtgcat gcatttgttc
    48301 cccataaagg aaaatcatgg cgaatttctc aggatcgata tgttcactca tttgcgcatg
    48361 catatttaaa gactctttcc ctaattccag catatctgct aacacagcga ttctgcgtcc
    48421 ttttgttggc agatttttaa aagtatctaa taccagtccc atggctgttg gatttgcatt
    48481 gtagacatcg ctcaaaatag ctgcaccatt tcctgccgtt agccattcgg ttctgttttg
    48541 agtgatagaa acatgggcga gcccttggcg tatctcaggt atggacagtc caaagaagcg
    48601 cccgatcgta tacgcaatca aagcattcgt tacattataa cttccaggca gcgggatcgt
    48661 aaatgtttct ccttctacta caaaatcggt ttgtgctttt ccttttgctg tcacttccgc
    48721 atgaacatcg ccatttccaa taccgaatgt tgtgactgtt tgtactaatg ttgccgttaa
    48781 aggtgtcagc aacggttcat ctgcgggcac aacgagtaat ccgtctgata caagtccgtc
    48841 agtgatttcc attttggctt tagcgattcc ttctcgcgac ccaagatttt ctatgtgtgc
    48901 ttcaccgatc attgtgattg ctgcagcttt tggttgagcc ataagtgaaa gttccgtgat
    48961 ttcattggcg tgatccatgc ccatttccaa aacgatcttt tctgtatctt ggggcatgtg
    49021 caaaatcgtg taaggaagac caatattatt gttgtaattt ccttgcgtct tatatgtttt
    49081 gtatttttca gacaagacag acgcggttag atctttcgtg gtggttttac cattgcttcc
    49141 tgtaattgca acgacttctg cgcctacttt ttccaagtaa taggttgcca attgctgcat
    49201 ggctttcaaa ggatctgcta caggaataac tggaaaattt tttggagctt gttcaacagg
    49261 caagctccaa aatgaagcag atgctccgtt tgtgatcgct tgctggataa attcatgtcc
    49321 atctcgcgta ccagcaagag gaacgaataa acttccttcg gttatcttcc ggctgtcaaa
    49381 ttcgacattg gtaatctttg tcagtgcaga gcattcgctg cccacggctt gtgcaatttc
    49441 ttgtattgtt agattcattg agatctctcc taaaaaaggt tgtgaaaaaa gcgtttggcc
    49501 taaacggcgg gttcgcatga ctctcacttc caagtaaatt tctctattcg tatttagaag
    49561 ctagaatgaa cgcggttacg caatcactcc agcctcttct ttatttctct ttattcattt
    49621 ttttcaaaaa aagattgacg ctgatggtat cgattcattc ctaactggat cagttcttca
    49681 atcaaatcac cgtatttcaa gcccatattt tcccataaga gtgggtacat actgaactcc
    49741 gtaaatcctg gcatagagtt taattcattc aggaataatt catttttatt tgtcaaaaag
    49801 aaatcgcacc ggctcaatcc gcttccacct aacatcgtgt aagctaactt cgcgtactct
    49861 tgcgcttttt gataaacttc ttctggcact tcggctggaa tctgcatttc gattttatta
    49921 ttgatatatt ttgcttcata atcatagaat gctacgtctt ttacgacttc accaggcaaa
    49981 gtcgtccgaa cgtcttcatt tcctaataca gcaacttcga tttcgcgcgc ttcaattcct
    50041 tgttcaacga ttgctcgaga atcatactga taggctgttg ctaaagcatt ttgcagctct
    50101 tctcggtttt ctgcttttgt aatgccgaca ctagaaccca tattcgccgg tttgacaaac
    50161 atcggataaa gcaaagaacc ttcacattga tcaaatactt ttttaggatt ttctttccat
    50221 tgattcttaa gtactggtac ataaggaact tgcggcacac cagcagcttg taaaatatac
    50281 ttggtcatga ttttatccat ggcacatgca ctggtcaata cgcctgcgcc gacataaggc
    50341 atattcaatg tctctaagaa gccttggatc gttccatctt ccccgtttgg cccatgtaaa
    50401 actggaaaaa cgatggctcc ttcttctttg atttcgcccg gattgatcac ttttcctgta
    50461 aagccttcct ctgtctgtcc acttgggtcc catgaaagat gcaagacatc tttgctggca
    50521 ggtttttctg ttagtaatgg acctttgacc cattgtcctt cttttgtaat aaatacgagt
    50581 tgaacttggt aataattata ataaatggca tttaaaactg aaaatgcgga aagaatggac
    50641 acttcatgct ctgcgctgcg tccgccatat agtaaagtaa tcttcaaaag attgtcctcc
    50701 tgtattctaa atcgttcagt gatttactct catattttag cacaaaacaa aaataaacga
    50761 ataacttatt tataaaaaaa cgagccagct tctaaaagaa cgagcgtcat ttattttttg
    50821 tcagctagat tatttgtccc gttttttata aaaagttatg ataaagaaaa ggagggatga
    50881 tgatggcgca aacaaatcca cgcagccgct tggcagaaat cattcgagtg ttcatcaatt
    50941 acaatgtagt gccaaacttt gtacagcaaa aaaatcccga acaggtaaaa aaagcctttg
    51001 aagaactagg ccccaccttc atcaagatag gacagatgct ttctgttcga gaagatttgc
    51061 tttcttctgc cttcactcaa acattcaaaa cattacaaga tagtgtacct agcgacacat
    51121 tttcaacggt caaaaagacg atcgaaacag aactttctct ttcattatca gatatattcg
    51181 atgatttttc aaaatcgcct tttgcctctg cttctatggg gcaggctcat cgtgccaagc
    51241 tgaagaacgg tgacgcggta gtcgttaaga tccaacaccc taacatcgcc gaagagatcc
    51301 gacttgatct tcaactattt gaacgagcga tccctttgat caaatacatt cctgaaacta
    51361 gcgtagttga tctaaaaggg gtactccaag aagtaaaacg ttccttgatc aatgaaatgg
    51421 acttcttaaa agaaagtcaa aatggcgaac aattctatca aaagaacaat ggctggaaag
    51481 agatccgcag ccccaagatt tatgacgctt tttgttcgaa aaaagtgatc gtgatggaag
    51541 aaatgtctgg taaaaacttg aatcatttaa tgaacgccga aaacaaaact gaaactttta
    51601 tcactggaat tcaaaacaag cagctgaaac aagaagttgc aaagctttta gttgagaact
    51661 ttatgaaaca ggtgtttgat gatggttttt tccatgctga tcctcatcca gggaatctgc
    51721 tattccatgt actaacaaaa gaagaacaga cacaagctag ccgaaaaact gaaacagtcc
    51781 atgaaaaaga gttcggttcc tttgcttttc gagcctccac ttctgcagaa gaccctgttg
    51841 cgccatatac catcaactac atcgattttg gtatgatggg gcatctttct gcaggactta
    51901 ggcaaaaact cacacaagcc gttttagcgc tgtatacgaa agatgcttat cgaatcgaaa
    51961 aagcggtcct tcgactttgt cagcaagaag gctcgtttga tgaaagtcgg ttccaccaag
    52021 aactgacaag ttttcttgaa cagtattatg attctcctat tgatgaaatc aacttgcaag
    52081 aagtattcac acatgtcgtg acgatttgtc atcaaaataa tctgcagttc gatcgtgata
    52141 tcacgctttt gctgaaagca tttgggacat tagaaggggt gatccgcgtc ctcgatcctg
    52201 aagtttccct catggaagtc gcttcgcctt ttgctcaaca ttattttctc actcatctgg
    52261 atgtagaaga tacattgaaa caaagcggat tagacttatt ggaagggatg aaggctgcgc
    52321 ctaagatccc tcaacagctc caccatctat tagaaatgtg gacttcggga caaggaaaag
    52381 tcaatttgga attgaaaaag caagacaaat tattgagcag gatcgaaagt atgatcaatc
    52441 ggcttgtttt cggtatgatt ttagctgcat tgatcgtagg gtcctccctg cttgtccaag
    52501 cagcacctgt agaaaacgca gaggtcgttt ccttattagg gatatttacg tatgctattg
    52561 ccgcattcgt cattattttt ttggcaatcg atgcattgat ccaaatgtat aagaagagga
    52621 aaaagtagaa aaaggttgtg acagaaagaa tcagcttcaa gaaataagaa ggggttttac
    52681 ataaattgtt tctcaaattt ttgtgaaaat tcggcttatt tttcgaagag gctacttctg
    52741 aaacaccgag aataaaaaat gtgaaaaagc tgttctgcac ccagtaataa gaacaatcaa
    52801 aaagggaaca tggaacacat ttatcctgtt tccctgttcc ctttttgatg tattcgagca
    52861 taaataaaat accttcgtta cctactatct tctgtacttg gtaaacctta gtcaattgcc
    52921 ttttttaacg cttgacgaaa agacatatga tctttctccg taaagggttt tggacccttt
    52981 gtccttatgc cagcttttct taactttcca ctatgataac gttgttctag aagcgtgccg
    53041 atattcgctt cgtcaaattc ttttccagag tgatggaaca ctcgcacacc cttcggcaat
    53101 acaagtgaag ctaaaccata atcttgcgtg atcaaaaagt cattcttctt aaccataccg
    53161 acgattttat aatccgcact atcagctccg cggtctacgt agacgatttg gacatgatta
    53221 gcgtattctt tggtcgtata atggtccaca ctggtcacga taaccacgtc aagaccatag
    53281 gattctccta attttatgac atcttctttt actggagaac catctccatc aatgaatagc
    53341 ctcattcttt ttcgccttct tccataaatg ataaacagtt actaatccgc tcagtaaaag
    53401 accaacattg atccattttg ccaagataag cagttgtaca ctttctatcg gcactgattc
    53461 atggttcagc gtgatcaata atagatggat tggctctccc atttcttttg ctaaaacaaa
    53521 caaaagcgtc atcaataaaa actggtggat cacactccct ttattttgag tagtatactt
    53581 gacaacgatc cggcgatcca ttggaatagc tgtatcagtt tgataatatt ccttatttag
    53641 ccagctgcct gttactacgt gccagaaact aagcagaaag acacctatcg caaaaccatt
    53701 tggaatcaag aggaccaata aagaagaact cagtccaagc aattgcatag ccaatggaga
    53761 ccatgttaaa cgtttcaaaa tccatggtcc gactattttt gctgcaatca agcctgctgc
    53821 ataaggcaaa tacataaaaa tcgaaagttt ttctaatccg tacagtatgc caacataaaa
    53881 actgctaaat aaaaaaagga aattccctag cattccattt agaaaagtaa acagatttag
    53941 ccagcttggc aacttccatt ccttcttctg gtgtcctaaa acaaacacga acaagatgaa
    54001 cagcagcaag aaaccataaa tagcaagatc aaaaagcctt tcatcgaata acaatcgggc
    54061 atttctcaaa agaaacaata agccaaagaa tatcaaaaat aaaacaagct ctcgcgtagc
    54121 taccagattt cttttgatgt ctttgaaatc cagttcgtaa cgcggataat gactaaccgt
    54181 atggtaggcc atgacgtaaa aaagtgtata aatagtaaag cttgctgcaa tctgagtcgg
    54241 tgcaggcaac tcaatcgctt gatacaggag aaatagccag atagctgcaa ataagtactt
    54301 tttcccatcc atattgataa aaccttgcgt cttttcgtga aaattgaccg tggtattagc
    54361 aggtacaagc catgctgcac tcagccctag caaaacactt gaaaaataaa ataaaggaaa
    54421 ataaaatacg cctaatattc caagcaatga accagcacca ccaatcagca gagcgatcat
    54481 cagcaacgtg taactatcta gaccaaatcg tagactgttg actaaaaata gtccagtcat
    54541 ccgaaaggca taaaacagcg taaatggcaa aatcgtcagc caattatgcg agtctgttag
    54601 tcccaaaaat aaaagataag gaataaaaat aaccgtgtta cttaagataa agggcgttgt
    54661 ttgtgtaaaa ttacgcccaa atcgtttgag tttttcgaac atgacaatgg ctccttaaac
    54721 agtcttataa ctaatctgct cttcgatttt agcattaaag gggaaataaa ccaattttac
    54781 agaatatatt cttgtaaaaa aaaatacaga aagaagcata agcttctttc tgcattttta
    54841 cggtacttga ttactcaagc agacaagccc ttctccacaa aagtcttgcc cgacacccct
    54901 gcatccggca ggtgataaag atagaaatca attatcctgt gcctccaaaa tcaattagga
    54961 gctctgtaaa ccagagtcct tctcgacccg tcgcataaat ttactttaac acagttccta
    55021 tgtttatgcg agagcttttt tcattttata atcgaccatt tgaaatcctt gaccgatatc
    55081 tgaaataagt tcttctgtaa tctcaaatcc ttcatgctta taaacctcga ttgcttgatg
    55141 attcccctga ttcactcgca aaaagatctc tctttccttt gtttgcgcag caagttcttc
    55201 ataccagcga aaaactgaag aagtcaatcc ttgaccacgt actttattta gcaaatataa
    55261 tttacttaaa taaatttttc catttatctc ttcataagca gtgtaaccga cagtcttttc
    55321 ttcgcttttt aataaaaagt aggacacacc ttctgtcagt tctttttgaa tctgtttttt
    55381 tgactgataa gttttcagca tgtaatccac ttgtttttga ccaatgatcg gcacaaaaac
    55441 ttccggccat acttcttgta tgactgccat cagctcatcc agttcatttt ctgttacttt
    55501 tattttttcc atacacccac gtcctttttt acattataaa tgaccttgcg cttgatggaa
    55561 taaaaagagc atgatcatgc tatacacacc caccgaccac ggtttcaaga aaatcacaat
    55621 ctgcataaat tccctaaaag ataatttcgt caaaccagct actagacaga tcaagtcgtc
    55681 tggcgcaaag ggaagcagca aggtaacaac tagtactttt ttaatatctt tcgtttttct
    55741 tgtcagcaat tcatcaaatt tctgatactt ttttggcgat aaaataagct ggacaaaggc
    55801 tacgccatag taacggacaa gcaaaaatcc gattgcttcc ccaatcacta ggccaataca
    55861 actatataaa agcccaaatc cattgccaaa catcagcatg cccgctactg aggagatccc
    55921 tcccggcaaa ataggaatga tcacttggat cacttgcaac agaacaaata tcatcactgc
    55981 atacttgcca aattgctgga taaacgcttg caaagacgtg ctcgatcgaa aaatcccatg
    56041 atgataagca taaagaatca acacaaagaa aaaaaacaga ccaataatgg gcatgatctg
    56101 aagacatttt tgtaaaactg atcctttttt agacatctat attccccaca tcttttttca
    56161 tttattaaaa ctgcctcct
//
LOCUS       DARBDN010000010        51170 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000010 DARBDN010000000
VERSION     DARBDN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.010"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            290..1135
                     /locus_tag="SCH06_000627"
     CDS             290..1135
                     /locus_tag="SCH06_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1077229.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="SCH06_000628"
     CDS             1416..2636
                     /locus_tag="SCH06_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HEG1077230.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="SCH06_000629"
     CDS             2633..5353
                     /locus_tag="SCH06_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1077231.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="SCH06_000630"
     CDS             5337..6281
                     /locus_tag="SCH06_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEG1077232.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="SCH06_000631"
     CDS             complement(6350..7360)
                     /locus_tag="SCH06_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEG1077233.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="SCH06_000632"
     CDS             complement(7540..7884)
                     /locus_tag="SCH06_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEG1077234.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="SCH06_000633"
     CDS             complement(7877..8311)
                     /locus_tag="SCH06_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEG1077235.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="SCH06_000634"
     CDS             8449..9186
                     /locus_tag="SCH06_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077236.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="SCH06_000635"
     CDS             9179..10390
                     /locus_tag="SCH06_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077237.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="SCH06_000636"
     CDS             10594..11376
                     /locus_tag="SCH06_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEG1077238.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="SCH06_000637"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="SCH06_000637"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEG1077239.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="SCH06_000638"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="SCH06_000638"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HEG1077240.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="tadA"
                     /locus_tag="SCH06_000639"
     CDS             14092..15021
                     /gene="tadA"
                     /locus_tag="SCH06_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEG1077241.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGTVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /locus_tag="SCH06_000640"
     CDS             14978..16027
                     /locus_tag="SCH06_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HEG1077242.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /locus_tag="SCH06_000641"
     CDS             16024..16302
                     /locus_tag="SCH06_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEG1077243.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /locus_tag="SCH06_000642"
     CDS             16277..16747
                     /locus_tag="SCH06_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEG1077244.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16764..17066
                     /locus_tag="SCH06_000643"
     CDS             16764..17066
                     /locus_tag="SCH06_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077245.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17083..17454
                     /locus_tag="SCH06_000644"
     CDS             17083..17454
                     /locus_tag="SCH06_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HEG1077246.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /locus_tag="SCH06_000645"
     CDS             17426..17785
                     /locus_tag="SCH06_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077247.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="SCH06_000646"
     CDS             17957..18964
                     /locus_tag="SCH06_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEG1077248.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="SCH06_000647"
     CDS             18989..20173
                     /locus_tag="SCH06_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEG1077249.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /locus_tag="SCH06_000648"
     CDS             complement(20610..22193)
                     /locus_tag="SCH06_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEG1077250.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVDINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHCQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22771..22914)
                     /locus_tag="SCH06_000649"
     CDS             complement(22771..22914)
                     /locus_tag="SCH06_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEG1077251.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="SCH06_000650"
     CDS             complement(23136..23615)
                     /locus_tag="SCH06_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEG1077252.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="SCH06_000651"
     CDS             complement(23688..23972)
                     /locus_tag="SCH06_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077253.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="SCH06_000652"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="SCH06_000652"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="SCH06_000653"
     CDS             complement(24316..25602)
                     /locus_tag="SCH06_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEG1077254.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="SCH06_000654"
     CDS             25740..26411
                     /locus_tag="SCH06_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HEG1077255.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="SCH06_000655"
     CDS             26377..26865
                     /locus_tag="SCH06_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEG1077256.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="SCH06_000656"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="SCH06_000656"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEG1077257.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="SCH06_000657"
     CDS             27826..28590
                     /locus_tag="SCH06_000657"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEG1077258.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="SCH06_000658"
     CDS             28823..31036
                     /locus_tag="SCH06_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEG1077259.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /locus_tag="SCH06_000659"
     CDS             31047..31493
                     /locus_tag="SCH06_000659"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEG1077260.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="SCH06_000660"
     CDS             31664..32923
                     /locus_tag="SCH06_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HEG1077261.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="SCH06_000661"
     CDS             complement(33012..33959)
                     /locus_tag="SCH06_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEG1077262.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /locus_tag="SCH06_000662"
     CDS             34353..35645
                     /locus_tag="SCH06_000662"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEG1077263.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="SCH06_000663"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="SCH06_000663"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEG1077264.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="SCH06_000664"
     CDS             37538..38413
                     /locus_tag="SCH06_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1077265.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="SCH06_000665"
     CDS             38679..40562
                     /locus_tag="SCH06_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEG1077266.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="SCH06_000666"
     CDS             complement(40637..40921)
                     /locus_tag="SCH06_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEG1077267.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="SCH06_000667"
     CDS             complement(40911..41645)
                     /locus_tag="SCH06_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEG1077268.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="SCH06_000668"
     CDS             41774..42397
                     /locus_tag="SCH06_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEG1077269.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="SCH06_000669"
     CDS             42589..43710
                     /locus_tag="SCH06_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HEG1077270.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="SCH06_000670"
     CDS             43717..46845
                     /locus_tag="SCH06_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEG1077271.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANERIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="SCH06_000671"
     CDS             46864..50058
                     /locus_tag="SCH06_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEG1077272.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="SCH06_000672"
     CDS             complement(50204..50911)
                     /locus_tag="SCH06_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEG1077273.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16746 a         8938 c        10630 g        14856 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cgggacagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acagtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatat cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgaaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttctgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga
//
LOCUS       DARBDN010000011        46915 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000011 DARBDN010000000
VERSION     DARBDN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.011"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(136..702)
                     /locus_tag="SCH06_000673"
     CDS             complement(136..702)
                     /locus_tag="SCH06_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEG1077274.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(730..2232)
                     /gene="eat(A)"
                     /locus_tag="SCH06_000674"
     CDS             complement(730..2232)
                     /gene="eat(A)"
                     /locus_tag="SCH06_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEG1077275.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(2490..3611)
                     /locus_tag="SCH06_000675"
     CDS             complement(2490..3611)
                     /locus_tag="SCH06_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEG1077276.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3737..4678
                     /locus_tag="SCH06_000676"
     CDS             3737..4678
                     /locus_tag="SCH06_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEG1077277.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(4828..5724)
                     /locus_tag="SCH06_000677"
     CDS             complement(4828..5724)
                     /locus_tag="SCH06_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEG1077278.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            5993..7333
                     /locus_tag="SCH06_000678"
     CDS             5993..7333
                     /locus_tag="SCH06_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1077279.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            7551..7994
                     /locus_tag="SCH06_000679"
     CDS             7551..7994
                     /locus_tag="SCH06_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEG1077280.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(8498..9916)
                     /gene="nhaC"
                     /locus_tag="SCH06_000680"
     CDS             complement(8498..9916)
                     /gene="nhaC"
                     /locus_tag="SCH06_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEG1077281.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(10319..11542)
                     /locus_tag="SCH06_000681"
     CDS             complement(10319..11542)
                     /locus_tag="SCH06_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HEG1077282.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(11573..12412)
                     /locus_tag="SCH06_000682"
     CDS             complement(11573..12412)
                     /locus_tag="SCH06_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEG1077283.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(12429..13109)
                     /locus_tag="SCH06_000683"
     CDS             complement(12429..13109)
                     /locus_tag="SCH06_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077284.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(13111..14184)
                     /locus_tag="SCH06_000684"
     CDS             complement(13111..14184)
                     /locus_tag="SCH06_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1077285.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(14240..14478)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(14521..14754)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14831..15502)
                     /locus_tag="SCH06_000685"
     CDS             complement(14831..15502)
                     /locus_tag="SCH06_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1077286.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(15589..18267)
                     /gene="mgtA"
                     /locus_tag="SCH06_000686"
     CDS             complement(15589..18267)
                     /gene="mgtA"
                     /locus_tag="SCH06_000686"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HEG1077287.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            18926..19363
                     /gene="ndk"
                     /locus_tag="SCH06_000687"
     CDS             18926..19363
                     /gene="ndk"
                     /locus_tag="SCH06_000687"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEG1077288.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(19385..20251)
                     /locus_tag="SCH06_000688"
     CDS             complement(19385..20251)
                     /locus_tag="SCH06_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEG1077289.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(20411..22504)
                     /locus_tag="SCH06_000689"
     CDS             complement(20411..22504)
                     /locus_tag="SCH06_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEG1077290.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(23253..23876)
                     /locus_tag="SCH06_000690"
     CDS             complement(23253..23876)
                     /locus_tag="SCH06_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077291.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(24035..25432)
                     /locus_tag="SCH06_000691"
     CDS             complement(24035..25432)
                     /locus_tag="SCH06_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1077292.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(25464..26435)
                     /locus_tag="SCH06_000692"
     CDS             complement(25464..26435)
                     /locus_tag="SCH06_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077293.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            26809..27234
                     /locus_tag="SCH06_000693"
     CDS             26809..27234
                     /locus_tag="SCH06_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077294.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(27722..28423)
                     /locus_tag="SCH06_000694"
     CDS             complement(27722..28423)
                     /locus_tag="SCH06_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEG1077295.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(28439..28879)
                     /locus_tag="SCH06_000695"
     CDS             complement(28439..28879)
                     /locus_tag="SCH06_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEG1077296.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(28879..29454)
                     /locus_tag="SCH06_000696"
     CDS             complement(28879..29454)
                     /locus_tag="SCH06_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HEG1077297.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(30302..30781)
                     /locus_tag="SCH06_000697"
                     /pseudo
     CDS             complement(30302..30781)
                     /locus_tag="SCH06_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(30940..31641)
                     /locus_tag="SCH06_000698"
     CDS             complement(30940..31641)
                     /locus_tag="SCH06_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1077298.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(31749..33158)
                     /locus_tag="SCH06_000699"
     CDS             complement(31749..33158)
                     /locus_tag="SCH06_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEG1077299.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(33206..35071)
                     /locus_tag="SCH06_000700"
     CDS             complement(33206..35071)
                     /locus_tag="SCH06_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1077300.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGKPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(35192..36043)
                     /locus_tag="SCH06_000701"
     CDS             complement(35192..36043)
                     /locus_tag="SCH06_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1077301.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(36353..37066)
                     /locus_tag="SCH06_000702"
     CDS             complement(36353..37066)
                     /locus_tag="SCH06_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEG1077302.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(37134..37460)
                     /locus_tag="SCH06_000703"
     CDS             complement(37134..37460)
                     /locus_tag="SCH06_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEG1077303.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(37583..37810)
                     /locus_tag="SCH06_000704"
     CDS             complement(37583..37810)
                     /locus_tag="SCH06_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEG1077304.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(38132..39385)
                     /locus_tag="SCH06_000705"
     CDS             complement(38132..39385)
                     /locus_tag="SCH06_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEG1077305.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            39446..40186
                     /locus_tag="SCH06_000706"
     CDS             39446..40186
                     /locus_tag="SCH06_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1077306.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(40272..41030)
                     /locus_tag="SCH06_000707"
     CDS             complement(40272..41030)
                     /locus_tag="SCH06_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEG1077307.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(41027..42055)
                     /locus_tag="SCH06_000708"
                     /pseudo
     CDS             complement(41027..42055)
                     /locus_tag="SCH06_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(42075..45242)
                     /locus_tag="SCH06_000709"
     CDS             complement(42075..45242)
                     /locus_tag="SCH06_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077308.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(45466..46350)
                     /locus_tag="SCH06_000710"
     CDS             complement(45466..46350)
                     /locus_tag="SCH06_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEG1077309.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(46445..46882)
                     /locus_tag="SCH06_000711"
     CDS             complement(46445..46882)
                     /locus_tag="SCH06_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077310.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        13422 a         9857 c         8018 g        15618 t
ORIGIN      
        1 ttttattaaa ataattaaat ttcatttcta aaggttgagt ttatattatc aaaagaattg
       61 tcataaccta aaaaaggcac tgctaagcaa aagcagtgcc ttgaaatatt ttatttaaat
      121 aacacaaaaa cataattact cataagaaac caattctgta ttatctacca tgaatgtaaa
      181 gaacccctca ttaggcatcg gatgaaaata agcattgatc actcttatca aggcattatg
      241 gcaaactaac agatagacat tttcttcgtc ttcgatgcat tctttcaata aaggaacgat
      301 ccgtgcatac acatctaaga ctgactcccc atttgggaat cgtacagcga acgctaaacg
      361 tgctttttga aagttctcat ctttgcttgg cagtccatca taatccccaa aatccatttc
      421 taccaatcgt tcatcaacgg tcagcggcaa gctgagacga tcagcaactg cttgtgctgt
      481 atctcttgct cgttgaagag gggaatggat gattttcgtg attggaacag gcaaatctac
      541 taccttttct gctagtttct gtgcctgcat ctgtcctttt tcagtcagcg gcacatctgc
      601 ccgtccgcaa actaatcctt gtgcgttcca agttgtttct ccgtgtctcg ttacataaag
      661 catgtgattc tctccttcgt tggcaaagtt ccccttaacc ataccttgtt gttcttgaga
      721 ttacaagggt tagattctct caagagaaat aatctcagta gatactttat ccaggaaggt
      781 ttgatcatgt tccactagta acatggcagg tttcacgttc aagatcagtt gttctaattg
      841 ttcttgattg aagacatcca aataattcaa tggttcatcc catgtatata gttcagctgg
      901 ctgtgataaa gatttagcca attccacttt tttccgttgg cccatactca tctgctcgat
      961 cttgttatga aaaacatctc tttccatccc aagctttcgg aggttgttca aaaatgcttg
     1021 gtagtctact tggtttttct ctgcaaattc cgccaacgtt cctcgattgt cttcataatt
     1081 ttggcttgca taactaatgc tcagatgttt tggctggtat ttttctccta taaccttgcc
     1141 gttgaatgcc cccagaagat aatggataat ggatgacttt cctgcaccgt taggacctga
     1201 aatcgccacc cgctgatgag gctcgattgt aaaatgaatt ggctcgaata acagattttc
     1261 ataccctaat tgaagatctt ctacgcttaa aagtcgctta tggtgagacg cttggctatt
     1321 catcgtcaaa gaatcgatat attcgatatc ttttaatagt ttttctttct cgctgatctg
     1381 ggtctccatc cgattcacga ttgctttgga tcgtttcatc gtccgtgcag catcagcacc
     1441 cactgctcct ttattcactc gtctagattc agtatcgatg aatccgactt gtttctttgt
     1501 tttatctcct tctcgggaac gagaccattc ggctttttca gctgctgttt tctttagcct
     1561 actgacttct tttttcaatt tttcattttg agccatttca aattcatcac gaagtttttt
     1621 ctgttcttca tagatagaga aattcccttg ataaagttcc agttgacttt tttcgattgc
     1681 taaaacatgg tccactactt catcgataaa tccccggtca tggctgacca cgatgaagcc
     1741 ttgttttttc tttttcaaat aagccgctac ttgttttcta ccagagatat ccaaatgatt
     1801 cgttggttca tcgattaacg ggaaatgagt gtcatccaca aataaaagtg ccagtaggac
     1861 ttttgtcttc tctccccccg atagtgtgct gaattctctc cataagattt caggatctgt
     1921 ttgcatcaat tggagctctc tttcgatttc ccatatctca aaatccgtaa tatcatttaa
     1981 cacgtaatag gttaaacgtt ctttatcttt tgtctgttgc gggaaatagg caaattcttg
     2041 ctgatggatt acttgccctt gataaggtag tttgttttgt agaatattca gtaaagttgt
     2101 ctttcctcga ccgtttcgtc cgataagtcc tagtttccat tgtgtgtcaa aatttagatt
     2161 tgcttgttca aataataatg tgccttggct gtcgtagccg aatgtcagat tttttatttc
     2221 gattttagac attttccatc acctcgtaaa aaaagaccag tcctattttc agaactggct
     2281 aaagaggatg caagggttgg atacacacaa aaagacccat acatcgaaaa aaccaagcca
     2341 atcccgaaaa tctgcacact gcttccttgt ctccacaagg tacagtctga atgcagcttt
     2401 catcaatcga cttaattttt caatgcacgg atccctcact ttgtcctata tttgaaatta
     2461 cgatagcata aagaaaatga ttttgtcaac tacttcggga ggatggtgaa aaatctgcta
     2521 agtgtctgtc ctaagatttt tgttttttct aatgtttgcc tgtgttccat tgcttcttct
     2581 aaacctattg gacccaaatg aatacttaag acaattggga gaaaatcaga aagtccttct
     2641 agctcttggt ctctacttcc gcaaatagcg attattggtt ttcgatattt ttttgcaagc
     2701 actgctacac cgtatggaac ttttccgtgg atcgtttgct gatcgatccg cccttctcct
     2761 gtaatgatga catctgcttg ttcgatcttt ttttccaatc cagtgatttg gctgactaaa
     2821 tcgaaaccag aaaccatctt cgctcccaac aaaaaaaggg ctccaccaat accgcctgct
     2881 gctccacttc ctggaatatc atctaaatcc acctcccaga aatcttttat ttgctgagca
     2941 atctttcctg cttgtttatc taagaaagct agcgtcgtat ctattcctcc tttttgtctt
     3001 ccaaattgcc aagcagctcc ttgttgacct gtatatggat tggtaacatc tgcagcgata
     3061 atcaatttta ctttagaaac aagaacgttt cttcgatcaa aatgaagttt tttagtagat
     3121 aataaaggat ttccttctgt gtacccttct aaagaagcac ccaaggattg gagtaatcct
     3181 agaccaccat cgctacaccc gcttcctcct aaagtgacaa taatttgttc tacttcttga
     3241 agcagtgcat ctttaataag ttctcctaag gcataactgg aagcaagtcg gatagtttga
     3301 tccgttggtt tatcaagtag atctaacccc aatgcttgtg cagattcgat gactgcggtg
     3361 ttttttcctt gccaagttgt caataaatag ctgatttttc gctgacggaa taagagatcc
     3421 atcccatcaa tggtacgcca tgttcccctg agcgcgtaat agattgcttc tgcagtattt
     3481 tctccgccat ctgcaatcgg cacattgatt tttcttcctt tacgatcttc ccagccattt
     3541 agaactgcct gatttagttc aaatgaagaa gcacttcctt taaatgaatc aattgccgcc
     3601 aaaatatcca tctgtatccc tcactttctt cttaagtaag acactttttt tcattttttt
     3661 caaacaaaac aatgctattt tcttccattt ttctatatac taaaagggaa ctcattgaat
     3721 aaaggagaga aaaaacatga aaatcgcaat agctggggcc ggagcaatgg gcagccgaat
     3781 cggattgatg ctacatcaaa gcggaaatga ggtcctcttg atcgatcgtt ggcctgctca
     3841 cattgaagcc attcgtacaa atgggttgat tgctgacttt aacggtaaag aagtggtcgc
     3901 aaaactgcca atctattcac cagaagaaat catcgaaagc aacgaacacg tggacttgat
     3961 cgtagcatta acaaaagcca atcaattaga tgatatgttt tgttcgatcc aatccattat
     4021 tactgacaat acttatgttt tgtgtttact aaatggatta ggtcatgaag atgtactgga
     4081 aaaatatgtg ccaaagaaaa atatcttatt tgggatcacg atgtggacag ctggtctagc
     4141 tggtcccgga aaagtcacat tgttaggtga tggagaaatc gaactagaga acttggaacc
     4201 agaaggcgaa gcatttacaa aaaaagttgt agaagtcttt caagaagcaa atttaaatcc
     4261 gatctatagc cataacgttc gttattccat ttggcgaaaa gcttgtgtaa atggaacatt
     4321 gaatggttta tgcacgattt tggattgtaa tattgctgaa ctaggcgcgc aaaaagcggc
     4381 agagagcatg gttcgaacaa tcgtatctga atttgcttct atcgcagcaa aagaaggaat
     4441 catactagat caagaagaag tgtaccaaca tattgcttct acttatgatc ctgacaacat
     4501 cgggttgcat tacccatcta tgtaccaaga cctgatcaaa aaccatcgtt tgactgaaat
     4561 cgactacatc aatggtgcca tttggcgaaa aggacaaaaa tatgatattg ctacaccata
     4621 ttgtgccttt ttgacccaat tagtccatgc aaaagaagga atccttggcg cagaataaaa
     4681 ggctctctga tgagaatcag ctgaatcagc agctggttct ctttttttaa gcccaataaa
     4741 agatcaaaaa gaaaacacaa ctctcatgat gccataagaa ttgtgcttgt ttgtttcagt
     4801 acataatctc ttcaaaatgt aggtttttta tttgttttca acagaggaga ggtcatattc
     4861 gtattgctca taaatagtgg aatcgttagt gataaatcgt tttgcccaat tttctgcatc
     4921 ataaaattcc aatagctctg ataggattgg cttaaatggt gtatgcagaa attccggtaa
     4981 ttcatctaaa tcacgttctc gaagcaaaaa aatattttca ggacgataaa aatgataatg
     5041 agcaatcgct tgattatccg tcactagttt cttttgaaaa tacatggatt caaatgtccg
     5101 caaagtcact ccttgctgac cctcccgcaa cagttccaga atcccgcgcg attcccctgt
     5161 ttttttcagg tactcttcat aagtaagata tccaggttgt tcattccctc gatgtggaag
     5221 aatgaaatag ttggtcgtaa catctctttt tataaattcc tgcttatagc tttctgctcg
     5281 ttcttttctc ccattattcg ttgcaccaaa aaatagatcc gtctttggtt cgctagaaga
     5341 aaaattcata tgtttcgaat aaaatgaact attatgtttc agcccaagtt cttttgcttc
     5401 caaaaaatca aaatgataaa tctcatcgat tgccggttca tcttgtgcct gcttcagcat
     5461 cgcctcgtgt tctgctttga agtgattcca aaaaaataac acaatttttg cattggtaaa
     5521 tgggcgcacg cgtcgagcca tctccatatc aaatccataa tctaaaaaaa cgatcagctg
     5581 ataatttgcc aactgttgtc tagctgattt aatgaattcc gactgtagta aatcttttcc
     5641 ggaccaaaca tctaaagagc ggatggaagg caaaaaataa agtgatttat tttttgcaac
     5701 tagcagtacg tcatttttgt tcatcttttc cgcctcactt tctctgtcac tttttcctat
     5761 gatagcctgt ttaaatagta aaaagccagt aaaacgtttc ctatatttgt atgaaaattt
     5821 aacatttgta tgaaaatatg atgaaataaa tcattcttct attaaaattc gcctaaaagt
     5881 tttctgaata gttgtaattg tctgaaaatt tgttatcatt agtcattgtt aaatattgct
     5941 atttattctt aatataaatt ttgattgtga atttaaaaga aagaggtcat ttatggaaga
     6001 taaaaaattg aaaaaacaac ttagctccag acatatcacc atgttagctt taggtggagc
     6061 aatcggtgca ggtctattta aaggaagtgg cgaagcgatt gggatcgccg gcccttctgt
     6121 attgattgct tttttgattg gtgggctgat tttatatatc gtgatgaaag gtctgggaaa
     6181 aatcgtttta agcggtggcg acacgcatca cggattatct ggtttgatac gcccttatct
     6241 aggtgctcat tctgctgatt ttactgattg ggtctactgg tctatgtgga ttatcaatat
     6301 catcgctgaa gctgttgcag ctgcttcctt tttgcagttg tggttcccgc acattccagc
     6361 ctgggtattt gtttttatgt tggctgtttt aactacgatc atcaatcttt attcggtacg
     6421 gttattcgca gaaacagaat attggctggc ttttgctaaa atcagtgtca ttatcttact
     6481 gatcattttt gctacttatc ttgtcggtca gcaaatgttg ggcacaggcg ttttccctac
     6541 ccttcagcaa ttgactgacc atggtgggtt tactcctcat ggtatgaagg gaatcatcag
     6601 ttctttgctt gtagttatct attcttacgg cggttctgaa ctgattgcta tcacggtaag
     6661 cgaagcagat gatcctaaac gtgcgattcc taaagcaatc aaaggtgtca tgggaagaat
     6721 catttccttt tacatcattc ctttgttttt gcttttgatt ctttttcctt ggaatacttt
     6781 agcaggcacg aatgtcagtc cttttgtgat ggtatttgaa aaaatgaata tcccatttgc
     6841 agcggatatc gtcaattttg tgattgtcct tgctttgttc tcatctatca attcgggtgt
     6901 gtatgcatct tcaagaattt tgttcttccg tttgaaggat cgaaaaggtt cctctagaaa
     6961 actagctgtt ttaaacaagc atcaagtacc gcaacgtgct gttttatttt gtaccagtgt
     7021 tctttatctt ggtgtagctc tttcttattt tgtcggtgac aaattatttg gctatctggc
     7081 aggttccctt tcgtatacag tattattgat ctggatcatt atcagtgcgg catcctttgt
     7141 actggcacta agaaaaggaa cattatggga taaaggaatc agcttttttg cattagctgt
     7201 cttaggattg attttccttg gtatcctgtt cacgaactcc attggggtaa ctgtattgac
     7261 tggcctgctt tacctgttca tttatttcag ttatcaaaaa aagaatgatg cgttcgtatt
     7321 gacgaatgaa tgaaatcgat agaaaatttt attttattta tgtggaatag atggagctat
     7381 tgaagaaagg agttgtgaca aaagtcttgt tgcaactcct ttttccgaat aaacagtctc
     7441 atgacctctt ggtaaacggt gttcaaaaac cctctgtgca aaataattga ttgttctcca
     7501 tgctcatgac atgatagaag aaaggaatga aaaaaaggag tttgttttaa atgaaaaagt
     7561 attggaagtt tttgttgatg atcggtgttt caacggtagt tatgtttggt atgatgtact
     7621 tgaatgtcta tgcgctcgat catatcttct tcagtcgtac acgagtattc atggcgttga
     7681 tgatgggtgc agtcatggca gtcatcatgc tgttgttcat gtggaaaatg tatgaaaaca
     7741 aaaagataaa tgttatgatc ttagccgcta gtcttcttgt ttttgccggt tccttgttta
     7801 tggtacgaag ccaaactact gtcaacgaca cagcttggat gaaggccatg attcctcatc
     7861 attctatcgc tatcctggca agtaaacgag ctgatttaaa agatcctgaa gtaaaaaaat
     7921 tagcggaaga aatcattcag gcacaagaag aagagatcga caaaatgaaa aaaatgatca
     7981 aagaaatgga atgaccatta tccgtccaaa taaaaaaaga ggatgttcca gaagttatca
     8041 gcttcaagaa ataagaagaa gctacttctg gaacgccgtg aataaggggt tgtgaaaaag
     8101 ctgccctgca tcaagtaata agaacagcca aacaaaaata gcttctccta tttttcgttt
     8161 ggttaggctt attaccgcag atgcaagctt ttgaacaccg tttattaaga ggttgtaaaa
     8221 tcagcgttct gacctgagta ttagagagac aaatggaaaa atagttcctc atattttgcc
     8281 attttttgag ctaataccga gggtcagctg attgaacacc gtttatcgag aggttgtgaa
     8341 aaagtcgctt agtttcgcgt attaagaaaa attttgtgaa atggctttcc acatttttgt
     8401 ataaatttgg cttaataccg agaaactggc ttttgaatac cgtttattcg taaaagggat
     8461 tgtgacaaaa gtcttgtcac aatccctttt tatgttttta ttgttctaat tgcgctgtct
     8521 tgcttactgc ttcttgcggt ttcacaaatt tttttgagat tccccaacct gtgaaggcac
     8581 tgaccatcga aaacacagga gaaagcaaac tgaaaaatac gaatggcaag taagtgagtg
     8641 taggaatacc aaatgtactt gctacgaaac ttccggcaat tccccaaggc actaagtagt
     8701 tgattactgt tccaccatct tctagcgttc tacctaatac agttggatca aatcctgctt
     8761 tttcataagt ttctttaaat gcattaccag gcagaataac agataggaat tgttcaccaa
     8821 taaaaatatt tactccgata cttgtcatca atgttgtaaa aatcaaattt ggtgtgttcg
     8881 tcatctttct tgatactcgt tccatcacgg ttgagatcaa gccaaattcg atcaacaatc
     8941 cacctaatga caaagttaga ataatcaatg acacagtagg catcatactt tcgattcctc
     9001 cgcggctaag cagtgaatcg atttgttggt ttccagtatt tgaaacaaac cctgattcga
     9061 tgaccccagc caacttcgtt aaggaagttt gtgggttttg aataaaaatc attcctactg
     9121 ctacagcgat attcaacaaa atcgttaaaa ttgccggcac ctttttccat gcacacagta
     9181 acattaaaaa taaaggaatc agtgaccaga ttgaaatagt aaagtttgct tctagaacat
     9241 cagtcacttc acgaatagat gaaagacttg cggctttact tgtgtgtcct aaaatcatga
     9301 ataaaaagaa agaaacaaca aatgccggga cagttgacca catcatatgc ttgatgtgtt
     9361 tgaacaaatc ggcatcaaca atagctgctg ctagatttgt tgattcggat aatggagaca
     9421 tcttatctcc aaaaacggca cctgaaacaa tagctccaac aaccagcgct ggatttaagc
     9481 ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt tgacataaca gtaaaggcac
     9541 tccctacagc gctacctacg attgcacaca caacaaatac agaagggaca aaccactgga
     9601 cactgatcaa tttgaaccca atgaccatta gagttggaat gatccctgct tgtatccata
     9661 cagcaatcaa tgaaccgact aaaataaaaa taaagattgg gatgattcct ggtttgatgc
     9721 cattgatgat tccttcgtgc agccaatctg tcgggtatct ttttatcact gcatacaaca
     9781 tgaccattcc gatcgctgct aagatcgtga tattaggtga gacctttaat ccgacaacgc
     9841 caatcgcaat gcctaaaaca ataaccatta atacaagtgt tgcttctaaa aaacttggtg
     9901 ttcctttttt tcccatgata atctctcctt ttttagttgt tcttatgttc taaaaaagtt
     9961 aagatatcgg attactccgc cgcaattcat ccgcgattcc tcctttataa aaataaaaag
    10021 acctgtttta aactaaggac gaatgactcc gcggtaccac cttaattaaa aacagatctg
    10081 tttttcactt tcaaactttt attcaaatgt atggactttc catgtaattc gtcaattagg
    10141 cttgatcggt tcacagcgac caccgacttt ctgaacaaaa cacctaaccg ctactgcgtg
    10201 aaaagttgac ttgtacgaag tttaccttcc ataagatcat ttgtcaatga aaaagaaaat
    10261 attttttcat ttttctgaaa attattttta taactttcac acacaagttt attttttact
    10321 agaaagtagc gccctcttgt ttttttcttg ctactatttc ttgatgttct tgcttgattc
    10381 tttctaatag ctttggctct ttcaacagat caagagctgt attggcgagt agttctgctg
    10441 caatcgcaat agaagcaagg cctttgtcac ttttagcagc agctttgaat tcttctgtgt
    10501 gtccggcaat atatgtctca gagattgcta ccgtaggctg gattgttggt atgacttggc
    10561 tgacatttcc tacatcagaa gaaccgagac ttgttctttg ttccgtttct atttcttcat
    10621 ctggaacacc tgcttctttt gcatgctgga agaataagtc atcaaaagaa ggagtaacga
    10681 tgacatcatc aactgcattt tggaacaatc caaactcaaa agtcgtgccc gtacttatcg
    10741 cagcacctcg tacgatattt tccacttttt catatacttt atctaatgtt tgccgatttc
    10801 ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat gacgttggca gctactcctc
    10861 cgtctgtaat gatcccatgg atattgacat cttttggcaa ttgcaagcgt agagcgttga
    10921 ttccattaaa cacttggatc aatgcttcca aagcatttac tcctttttca ggtgctgctg
    10981 ctgcatggga agcgacaccg taaaatttga tgtcgactgg atcattcgct aaagattctg
    11041 tcgttttccc ataacgaaaa gctggatgga cgcataacgc tacatcgaca tcctcaaaaa
    11101 aaccttctcg aacaaagctg cctttagctg atccgttctc gcccccttct tcccctgggg
    11161 tgccatatac acggatttct ccaccagttt catcaatgaa ttgcttcact atgctggcgg
    11221 ctaatacgga gtaagtacca aacaaattat gcccgcatgc atgaccaata cctggtaaag
    11281 catcgaattc tgccaaaaag gcaattgtgg gaccgggttt attggaaata taacgtgcat
    11341 caaaggctgt tcggtgtcca gctacttctt tttctaccca aaacctttct ttttctaatt
    11401 gtttaatcaa cgctgctgag gaataaaact catagttact tacttcagga tgttcgtgga
    11461 tatctagagc aagtgcttga tattctggta aacgatattg gattagatcc ttcaattggt
    11521 ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc tagtcatttt tcttattttc
    11581 tcccgaatgt ttcccatgca ggcacgcttg atccttttga tgttttctcg attactttga
    11641 ctgtgtcttc tgtttgataa gcgtctacta ttttttgata cgttttattg ttttcatctt
    11701 cttttcttgc aacgatgata ttcacataag gacgtgcatg gtcatccact ggttctaaga
    11761 agatggcatc agaagcagga ttaaatccag catctacagc tacaccgcta ttgatcactg
    11821 aaatgtctac atctgacaaa gcacgtgctg tttgggaagc atctaattca gaaatgtcta
    11881 gattttttct attctcggta atatcagaaa cagtgggcgc ttgtcctttt gccttatcca
    11941 ctttgatcaa tccagcagtt tgcaataaca gaagagctct gccgccattt gtaacatcat
    12001 tagggattgc tacttttgct ccgtctttga tatcagctac atccttcaaa gtgttagaat
    12061 aaattcccag cggtgcattg acagtatttc cgatcgatac taaatcagtt ccgtgttctt
    12121 tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt caaatcaatc gatccatctg
    12181 ctaaagccac atttggttga ttgtaatctg taaatttcac gtattccaaa ttaatgttct
    12241 cctttttcaa acggtctttc acgttgtccc atacatctgt atcttctcca ataatcccta
    12301 gttttacgat agtttctttt ttgtcagttg tatctgcttt tccttggcta caccctgcca
    12361 accaaataat tgctacaaat gtaatgacta caaaacgaat aatttttttc attttttctc
    12421 ctccactttc aatgtgtaat ttttttaatc agttgattac tgataaattg acttaaaaaa
    12481 actaagatta gaatcaataa tgtagccaca atcgttacat ctgtttggaa tcgattatac
    12541 cctctcgata tagcaagatt ccctaatccg cctgcaccta ctgctccagc catggtagtc
    12601 agtccgatca cgttgatgat agtcaacgcc gagacccgaa tgataccagg caaaccttct
    12661 aacaaataca cacgtaaaat gataccgatt ggactggttc ccatcgcttc tgccgcttcg
    12721 atcaccccag gatcaacttc tagcagtgcg ttctcgattt gacgagcaaa aaacggaaca
    12781 actccaaaaa tcaatggcac taaagctgct ttcgcaccaa tcgtcgttcc aactaagaaa
    12841 cgagtagtca atgctaaaag agaaagcaag ataatgaaag ggatggaacg aatgatattg
    12901 atcagcttat caagtatttc aaatagcaga cggttagcta gtaatccatt agggcgtgtc
    12961 actactaacg tcacacctaa gatgattcca atcatcccgc caatgaatgc tgtccaaaaa
    13021 gacatatata gtgtttgctt cgtcgcttcg acaaattcat ccggaatcaa ataaacattg
    13081 ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct ccttcgatca ctttgatacg
    13141 actatctaaa tcgttttttt gtaaaatatt tatttttaca ccagatttga tcaaataatc
    13201 caatgctttt ttccgctgtt tggtttctcc agctaaagta acgatcaaac tccctaacgg
    13261 cgtttcttgt aataactcta cattgccata taaaatattc gctgttactt gatatttgct
    13321 gtacagatga gcgattagag gttcgttcgt ctgatttcca atataactta attccaccag
    13381 ccatttattg gcgatctgat cggcaaaagc agaatgggca atgatcgttt ctaatgcttg
    13441 gtcaagatga gtagctgttc gaataaaatc tttggtcaat tcttcttcag gattgctgaa
    13501 gatctggatg ctgctacctt tttcaacgat tcttccatct tccataaccg ctaccttgtt
    13561 gcagatttct ttgacaactt gcatctcatg agtgatcagg acgattgtta aacctaactg
    13621 gcgattcaat ttttttaaca atgcaaggat ctgaagggtc gttttcggat caagtgcact
    13681 ggttgcttca tcacataata ataccttagg ttcattcgcc aaagctcgtg cgattgctac
    13741 tcgttgtttt tgtccccccg acagttgttt aggataagca gatgcttttt cttccaaacc
    13801 gacaagttcc agtagttcat tcactttttg acgacgttcc tgtttcgatt ttccagaata
    13861 ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt tccattagat tgaaatgctg
    13921 aaagatcata ccgatggcct ttctttcttt tcgcaattct ttgggagaga gctgactcag
    13981 attcgtctga ttgacaatga cttctcctgc tgttggtttc tgcagcaaat tcatcacacg
    14041 aactaacgta cttttccctg cacctgagta accgacgatt ccataaacat cgcctttttc
    14101 aatcgttaaa tctacagaat ctactgcctg tatctctttt tctttttgtt tgaaacatac
    14161 agaaacatct cgcaattcaa tcattaaaat tcctccttat ctaaaaaaag cgtcctcaag
    14221 aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt gttaccacct catgttcaag
    14281 ctgtgttcac acacaactcc tcttcaagta cgatcatact ctagcaagat atcggtcgca
    14341 gccgtcatcg ccttacatct atgctcggga tgaattgctc gatggccatt ttccaatagt
    14401 cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa aggttcttct atcgtactta
    14461 ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt actaacataa actatgtcag
    14521 taaaaggacg acgtatcgcg gtaccacctt ttttcggaag tttccttccc tcaagcccaa
    14581 catctcaaaa agagagattg gcgttcgttt taacggtcga acagttccga atttgcctac
    14641 ttatcgacaa attattctcc aaggccattt tcagcttttc ttacttgact cttctcacca
    14701 gccagagcct ctctgcaaag tttccaaact tactttcctt ttcaacgaaa tcgatatttt
    14761 gttgttggga ttaatctaca tgaggaaaac tgaaaagtca agtacgaaat tcaaattatt
    14821 ttttctatat ttatttttct gtttttttat ttaacatttc aataacagtt cgaagatctt
    14881 ttccttccgc aagaagtttc aatttttcct tttcttcgac ggtataattt cggacaaaac
    14941 tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga agcagctgtt gctcctacta
    15001 aagaatcttc cactgcaaag gctgaactag cttctaatcc tgttcgttcc aaagctgtca
    15061 gataaggaat cggtgaaggc ttgttctccg acacttcgtc tccgaatgta aacgtgtcca
    15121 agtaatcagc taatttaaag tgatccaaga tatctgttgc tcttttcgta acagtggtcg
    15181 tagcaatgcc tagtttcata tgacgttctt ttaagtctgc caatatttct tttgcatatg
    15241 gttttaagtg gatggctccg cttgtcagct gttgataaaa atattcttca cgcttcgctc
    15301 ggacttcctg tactttttca gggctacctg ctgctttcac taaaatatca aaactttgtt
    15361 tccagttttt tccgccccaa gcgtcaacga tttcttttgg gatatggata tcaaattgct
    15421 gaaatcccca aagccagcca tcacgatacg ttttttctgt gtcaactaac aaaccatcta
    15481 aatcaaatat tgcacctttc atctatacat taatcctttc caaaacaata cacatagttt
    15541 agcacgactg gtccaaaaag aacagaagca aagaaccagc cttctcgttt ataagagttc
    15601 ttggaatcga cggatataga ttttcttcac agctgtcaca agcgccagat aagcgatgac
    15661 tgtagcaaat aaccataacc agtaattgcc aggaagtggc atcaagccta attcagcacc
    15721 aaaacttgta aaaggaagga cagaaccgac aataattcct aatgtagtga taacaaacat
    15781 ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt gtacgcagtg catggagcac
    15841 taaggtttgt gtccatagtg attcgacaaa ccatcctgca tggaataatg cgatgaaaat
    15901 cactcgctgt gaactatcca atgtatggaa acttccgccc actacagcag gacaaataac
    15961 aaaatacatc aacaagtaag tagtaatatc aaatatcgaa cttgttggac caaagtaaac
    16021 catgaattcc ccaatactag atgcattcca tttttttggc tcgtccaaat attctttatc
    16081 catccgatcc catggcaagg aaatgcagga aacatcatag atcagattca aaaacaaaag
    16141 ttgtaaaggc agcattggta aaaatggcag gaacgtactt gcaatcagca cggaaaacat
    16201 attgccaaaa ttagaacttg ctgtagcctt gatatatttc atgatattcc caaaagtttc
    16261 tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct ttttctaaaa ggatcacgtc
    16321 tgcagattct ttcgcaatat ccacagctgt atctacagaa ataccgatat cagccacttt
    16381 cattgcagga gcgtcattga taccatctcc taaaaatccg acagtatgac catttttacg
    16441 taaagctgtc gtcaaacgtg ctttttgctg aggattcaat tttacgaata cttcatggtc
    16501 ttcagctact tgtgctaatt catgatcact catttccgag attttctcac cggtaaccaa
    16561 ttcattgatc tctagaccta cttgacggca cactgaacgt gtaactaatt cgttgtcccc
    16621 agtcagaact tttacagcta caccatgttc tttcagagct ttcaacgctt gtttcgttgt
    16681 ttcttttggt ggatcaagga aagcaagata accaatcaaa accatgtctg actcatcttt
    16741 gactgaaaat tctccaacga cgcttggatt ggtcttttgt gcgacaccaa tcactcgtaa
    16801 gccatcttca ttaagtgact gtacttttgc aagtacggct tcttttcgtt cttttgttaa
    16861 tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg ttcagcattt cttcaatcgc
    16921 gccttttgtg atcatttgtg ttttaccagc tggatcagca accacaacac tcatacgacg
    16981 acgttcaaaa tcaaaaggaa tttcatccac tttttgataa ttgatcttat ctgtatctaa
    17041 agtttctgtt gcttcatcaa tgatagccac atctaacaaa tttttcagcc ctgtttgata
    17101 gtagctattt agatacgcat ggcgcaaaac acgatcatct tcatttcctt cacaatccat
    17161 atgatattca agaatgattt tatcttgtgt caatgtcccc gttttatccg tacataacac
    17221 atcgattgca ccaaagttct ggatggcatt caaatttttg atcactgttc cttttttggc
    17281 catcacactt gctcctttga ccaaattcgt cgtaacgatc attggaagca tttcaggtgt
    17341 tagaccaact gctacagata gtccaaaaag aaaagcttct agccaatccc cttttgtaag
    17401 cccattgatg acgataactg ctggagccat caatgacata aatttgatca gtagcatgga
    17461 tgttttatgg atgcctaatt caaagcttga ttgaattggt ttttcagata gcgtttctgc
    17521 tacatgacca aatagtgttt catttccaac agaaacaatg attccttccg cacttccact
    17581 gatgacatta cttcccataa agacaagatt ttcgtaactt gtttcgcttt gctgatcgtc
    17641 ttcacatact ttcgcatgct tttctactgg atagctttcc cctgtcaatg ctgcttggga
    17701 aatgaataaa tcctttgcgg acaataaacg catatccgct ggtatcatat cccctgctga
    17761 aagccgaaca agatctccac agacgatttc ttccatagga atctctgtgt actttccatt
    17821 acgttttaca gctgccgtta ctttcacaag tgatttcagt ttttcagccg cttgattgga
    17881 acgtacggac tgaatcaacg tcattgtccc gctgacgata accatagtga agataatggc
    17941 tacaccgaaa agatctttat ctccaggagc tgctaataca tattccgtga tgaatgaaat
    18001 aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg tatgctttca atatttctac
    18061 aatgaatggt gtttttttgc catatgaaat cgcattttca ccgtaatttt ctcttgaacg
    18121 ttcgatttgt tcttctgtca atccatttgc tgatgcatgg aatagttcaa ataattcttg
    18181 tttcgttttt ccagcaaaag ctgcatagat tttttgtgta tctttctttt tttccatctc
    18241 aatctctcct ttgtgtccaa aagacagctg ttctcgctgc ttttggtctt tagctattca
    18301 tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag atagataata gccctggcct
    18361 ttcctctaga tccttgtttt tcgaatgact gtcatccatt tgttctcatc tcctttacta
    18421 agtaatttta attcatgact tccaatcatt tttcgaatag ttatttttcc aattagacca
    18481 cctccttttt atttttcacc gatggggatt tgcggcaaca aaaaaacctc tcgccaaata
    18541 ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc tcagatctca tcgttgagtt
    18601 ttgacactgt acaacgtaaa aagcagatac ctgcttttag ctaccttatg aaaagcctta
    18661 tctcgacaat tcctgttcta cccattggcg tctctcgacg tttttgggca gtagcctatg
    18721 tttgtatagg agcctcacct aacaaatctt attcggtttt ccttcgttaa tataacaact
    18781 aaaaaagagg atgtcaaatc aattttccat gtttttcata ctttttttaa aatacacacg
    18841 ttatattcct gtctcacgcg gttttatttg tctcattttc cacctcccgc tataatagaa
    18901 atatagtagg aaacgaggtg ctgttatgga aagaacactt gttattatca agccagacgg
    18961 cgtgagacgc catttagtcg gaagcatcat ccaacgtttt gaagcaaagg gactggccat
    19021 tgctgaaatg aagtttgaaa ctatgactcc tgaattagca aaagaacatt atcagcactt
    19081 gactgagcgc agtttttttg atgaactgat cgattacatg acttccggtc ctgtcgttta
    19141 tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt aagatggttg gagcaacaaa
    19201 agctgccgat gctgttccag gtacgatccg aggagactac gcgctgccgg ggactgaaaa
    19261 catcattcac gcttctgatt cccgtgatgc tgcggtaaaa gagatcgccc gctttttccc
    19321 gccattcgat ataaacaaac cgtctgaaaa agcggcgaag tgatacaaat tctaaactgc
    19381 tggtctagtt gctgggttca gcaatggcca gcagtttttt ctctaaggac ctccgttgat
    19441 tctttcctaa catatattcg agcactgtga agaattcttg gtagtctttc gtcttttctt
    19501 cccctaaagc agcagaaatc aatctttgat aataatctgc catcaatgtt tcatagatca
    19561 ctgtacttct ttctttatgt gctaagctcc gtttcatatc ttcattcaca ctacgtgcct
    19621 ttttcaaccg accattttct atataaaacg aagtcaggtt cattaaaaaa gtaaagagat
    19681 actgctcatg attgttcaac tgtgctaatc gtcgcattct ttttttgatt ttcaaataat
    19741 tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc agctagaata gatagttcaa
    19801 attgaccata gtctggtatc tgcatcaagt attcttcaat gattcggcat tcataacgta
    19861 aaaattcaaa ttctgtctca gatacttctg ttttttcgac catgtgaaga ttcaaaacca
    19921 aataatacag atcttctgtt ttcttaaaat gcctacggtt attgctgatc tctttataag
    19981 gatcaaagct gtcttcttgt acccgatcta gcattcgtct ttttttcttt aactttattg
    20041 gttcatccag ctggtttcgc atccattcat attctgcaag tgtcatgttc attcgctcta
    20101 aaaatgatct caatgttaca aatgacattt ttttcactga atttgtctca atcccgacta
    20161 gagaagtctt aaaacagatt ccttccgcta attgggactg tgtcaacttc ttgttgactc
    20221 gaagtttctt gatcaattca ccatcataca taatagttct cctttttaat ttaaattttt
    20281 ccacattcaa taaatagata cgttaaaaag gaaaaataca cgaaaaaaat aaaaaaatgt
    20341 ttttttcata aaaaatacca accttcaagc attagaatgt tgtctaacta ctgaaggttg
    20401 gtttgattgt ttattgatta tttttttgct gttcaacgtc tgttcttgtt actggatata
    20461 agttggttgt tgttttatta ccattttttg aaaagacact tgtcgaatgt tcgccttttt
    20521 gcttttcgat tgcttcatta cgttccgctt catttttata gtcatatttt ttcggatcaa
    20581 tcgtctcaaa tccgtttggc acataaaacc gcaagagatt ttcctgattc agcttatctg
    20641 aaagacttaa cgcagtcttg actttttcct gatctttgga gatttcctca tcgattcctg
    20701 ctgctttcgt atcgatgatt tctcctgtct gattattgta agcttttcct cctaggacgg
    20761 tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac tacttgatca tgctgagaag
    20821 ataataagtc tgtaccaaaa tgaagataat ctttatcatc gattcccaat agatgtagta
    20881 atgtcggcaa aacatcgatt tctccaccgt attcatgatt gactgtccct ttagtataac
    20941 caggcatatg gatcatcaat ggcactcgtt gcatctgtgc gttgtcaaat tcatcccatg
    21001 tatctggatc tttaccaaga gcgcttgcta aatctttatt atctgtattc gagatcccaa
    21061 aatgatcccc gtaaatcaca aagattgaat tttggtaaat accagatttt ttcaaatacg
    21121 taaaaaattg ttccaatgat tgatccagat aatgtgccgt tcgaacataa ttatctactg
    21181 tgctattgcc agtattcaaa gatggaaagt cgaaattctt gtcatccgta taataaggcg
    21241 tgtggttggt tacggaaaga aatttcgtgt aaaacggctg ttgtagatgc tcaagatatt
    21301 gggcagattc tctgaataaa tctttatcta atatcccata acctaacgtt tcgtcggatt
    21361 catcaaaata agatcgatca aagaaattgt cataacctaa gtttttatat acatgatctc
    21421 tattccaaaa actagctaca ttcccatgga aaacagcgct tgtatagcct tgcttttgtc
    21481 caaggatcgc tggtgcggct tgaaagacat tgtctgaccc aagttctgtg aataatgagc
    21541 cttgaggtaa accaaatgtg ccagtttcca acatattttc agcatcactt gtctttccct
    21601 gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc ttgattctgg aaaatactat
    21661 ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt aatcaaaaac tgctggaaac
    21721 tttctaaatg gagaacgatc acatttttcc ctttagcgat cccaaatgtt tcgggatttg
    21781 gctctgcata atgtttcttt gtataatcta aaacttcatc aatcccatta ctgcttgcat
    21841 gcgcgcgaac actgctagtc attcctgttt tgattccgtc ataaatagta tacgcatcga
    21901 ttcctagata tttgacaata tatgaacggt caaatgttcg ctgcagcaat tgtggacggt
    21961 tggcttcgct cagcgctaga tttcctgaaa aaataagccc tgaaagacag gtaacagcga
    22021 tagccatcgg tttgccgaca gggttgcttt tgataggtat tttcttgacc ttcaaccaaa
    22081 ccagtagccc aatgaacaca gcgatatcca gccagtagat gacatcatgg ggcttcatca
    22141 aagaaaagga gcttcctgac aatccttgcg acactttcga aaagcctaat acagatttga
    22201 ctgtaatgaa atctgtgaat tcccgataaa aaataatatt caagtacaac aaaagcgtat
    22261 ttaaaatatc aatgatcaaa agaatagcta acgctggctt tggcttttta atatacaaag
    22321 aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat ccacaagata aagtactgga
    22381 tcgtaccttc cacacctaat gaaaaatctg catagtaggc aatgatcgtc ttcagccaga
    22441 aaaagaaaac agctgtcaaa acgattgcta aacgattttg gcacaatttt ttaagttgtg
    22501 tcacgtatat cacttctctc tattcacatt ttttcttatt ttgctcctga aaaatgaaaa
    22561 tttcctaaaa aagttgttat cttaagattt ttttattctt tctaaagatt attccgtcca
    22621 cttttcacag cataaaaccg ctgcgatgta agcgattaaa ctaatgaaga gataaaagtc
    22681 ttgtggtgac cgcttcactc cacggtattc aaaagccagt ttctcggtat tcgtacaaaa
    22741 aaagaggctg tgacaaaatt cttgtcgcag ctccttattt cttgatgcag gacagctttt
    22801 tcacaacttc ttccttaaac ggtgttctcc tgccaactcc tcggccacaa gtcacaatat
    22861 ttataaaaca tgagaagctg ttttttgaaa ttgttccttg tggctcagag ttaaacggca
    22921 ggctcaagac ctcttgatac acggtgttca atcagctgac cctcggtatt agattatgtc
    22981 aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa aagcttgcat ctgcggtaat
    23041 aagcccaacc aaacgaaaaa tataaggagc tattttttga aattgctcct tgtggctcag
    23101 agttaaacgg caggctcaag acctcttgat acacggtgtt caatcagctg accttcggta
    23161 ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc gtttgtttct ctaatactca
    23221 ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc cataggattg atattgtcct
    23281 tgtgatgact cattcgtaat aattgaggct tgattttctt cacttcccgt tatcgtttgt
    23341 ccactgccag aatctgaagg acttgttcct gtcgactcgt ttttttgaga agagacagtt
    23401 gttttcttga cttgttcatt tgtctttttc cattccgcta aacgatcggc gaccactttt
    23461 ttgtctactt tttcagaata agcggtgatc acttttccat ttttcaaacg ggctactttg
    23521 tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt ctttaaattg atattgtctg
    23581 agagaaatcg cactaagtac gtcatcgata ttaataaatt gattttcttc ttttcctttt
    23641 ggcaaataaa tgtccaattc gcctttttcg taattggcag ttattttata ctccgcccac
    23701 caataagttg agaattcttt tttgaaatta tctactgatt ctttgcttgc tacgattttt
    23761 tctgtttctt tctgagcaag atctgctgtc atttttcctg aaaatgctgc ggataaaata
    23821 agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg gtcttttttt cctcatgctt
    23881 tcctccactc ctatttaatt ttgactattc tattatatac aaaaaatgaa atagaaagac
    23941 aaaaaagttg aaaaagatcg taaataattg aacttctttt tcacaaaatg gtaagaatgg
    24001 agaatttcac gcatttgctc tcaactattc tttcttaagc ctcaaatccg tttttatctg
    24061 atacgtcttt gaaccaatga cccgattttt tgattgttct ttttccatct tgtgctaagt
    24121 ctactgaaat aaagccatat cgattcttat atgcattggt ccacgaccag ttatccatac
    24181 atgtccacat atgatagcct aaacaattgg caccttcttg aatggcttga tggacatatt
    24241 tcagatgaga ttggacaaat tcgatccgat aatcatcgtg gatcatgcca tcttctttga
    24301 taaatcgtgc ttcgttttct acacccatac cgttttcaga aataaagcag tcgatatttc
    24361 cataatgatc tcgtacattg atcaaaatat catagattcc ttgttcatag atctcccatc
    24421 cgcgataagg attcatttta cgaccaggca tttcataatt gtcgaaataa tcctcaggca
    24481 ttggaccgtt tttagtatcg attggtgttt cttttgcttt tacccggcgt ggctggtaat
    24541 aattgatacc taaaagatct actgtatttt ctttgataac cgtcaaatcc tctgcatgga
    24601 tcacaggcat gagatcaagt tcttttacta tctcaatcaa ttcacttgga aactcgcctt
    24661 ttacagctgg atcaaggaat gaacgattga agaacgcatc tgctatttgc gctgctttaa
    24721 catcttcagg gtttgattcg tctcttggat agcttggtgt cagattcaag atgataccaa
    24781 taacaccacc ttgctccatt tcatggtaag atttgatggc taacgctgaa gccaacgctt
    24841 catgatagcc aacttggatc gcttttttca tatctgactc ttctggataa tgccatcgat
    24901 ataaataacc tgcttcgact ggaacgattg gttcattatg agtaaaccat ttttttactt
    24961 tcgaaccaaa caattcaaaa caacttttgg catatttttc ataggcttca accgtttctc
    25021 ggttcaacca tccgcctttt tcttgcagat acatcggcat atcgaaatga tacagattca
    25081 caaagggttc gataccgttt tcaatcaact catcaaaata acgatgatag aaacgaacgg
    25141 cttcttcgtt gattgttcca gattcatcag gtatcaaacg gctccattgg atagatgttc
    25201 gaaatgaatt atgcccagtc tgtttcatca actgtacatc ctcttgatac ttcgtataaa
    25261 cttgcgaggt tttttcaggt cctacttgat caaagaactt ttgcggttct tttttgtacc
    25321 aataatcaaa aatgttctct ccttttccat cgcctgaaat ccttccttct gtttgtgggc
    25381 cacttgctgc agaaccccac caaaaatttg ctggaaattg atattttttc atcaaagcac
    25441 ctctttttct tttttagttc gttttagttg attccatgta tgatattttc catcacaatc
    25501 actttttcat tttcttcctc ttcttttttg attcgtttta acagctgttc tgctgctcgt
    25561 tccccgattt tatctgttgg tggcgtgatc gtgattttcg gaaggatact cagatcgttt
    25621 ttatctaaat aatcatagtg actgaacgca atatccttcc cgattctgac accttcttga
    25681 ttgaaacatt cgatggcacc aatcgacata ttgtaattgc tgacaaaaat agcagttgcc
    25741 cctttttcta ataatgcttt tgccccgtaa tagccgcttt ttctagaata gtctcctgta
    25801 aagacctcta attggatcga tggatcattt tggaccgctt ctttggctcc tgctaaacgt
    25861 tctcttgcta cgtagtctgt ttgagtggca gcaataaatc cgattttttt atgtccttgt
    25921 tcaccatgat gagcgatcac ttttgctaca ctttctcgat cattcactaa tattgtatca
    25981 atacctgctg gtccttctgg acaattcaat gcgataactg gaatactcat ttttgtgagc
    26041 atttcaaatc cagaccactc ttcttcggat aagaagacaa tcagcccatc gatcacatgc
    26101 ttcatcaggt attcaatttt ttgttcaatt ttttctggct gatcggcaaa cccgcttaat
    26161 aataagctat acccattttc ttcagctact ctttcgatcc ctgagacaac ttccgaccca
    26221 aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga agcttcgatt attcttcaac
    26281 cctttagcaa tgatgttttc tttatagtcc aacgctgaaa tcgcttctgc tatttttttc
    26341 atgttctttt ccttcagttg ctgaccattc aagtaacggg aaactgttcc cactgaaaca
    26401 ccagccatct tagccacatc acggatcgat gccatacatt ctcactcctg ccagttacat
    26461 ttgatttctc tttcttgttg ttcgattatg atgaccgcat tctttgcata gtgttgcttg
    26521 tcatcaatat ccatataact aaagtcttca gtagagcaac ttcctctcac tattaattat
    26581 acttaaacaa gtatttgaac cggttcattt ttaatatagc atttttttaa aagattgcaa
    26641 cactttttta aaacgctttc tgaaagtggc ggattttttg cctttttaaa attttattct
    26701 aaaatttact ctatttgtgg gtgttttgtg cgtttttctc ttccatccgt ttgaagtttt
    26761 acattccaat ggtataattt ctttatccta tcaaatgggg gaagtatttt gaagaaatta
    26821 atcgtactat ttattttgtc tgcgggactt ttgacattga ctggctgtga tttgtttggc
    26881 ggctctgacc aatcctcgga cgaaacaacc gattcttctg tcttaaaagc ggaaaaagca
    26941 gataccacca acagtgtata tacgctaaaa gtacgtaaag atatggattt atccgcggga
    27001 cagttgacat ttacagataa aaaaatggaa tggacacgca cgtatcagac acaaggaact
    27061 gattcttctg aatcatctga agaaaaaaca gtgctgacag atatcaagat cactaccaaa
    27121 gatgacgaat atattatttc aggaaaagaa aataaaaaag aaacaacagt catatttaca
    27181 aaaatcggta attaccgttt gaaggatgag gatggcaaca tctacagtct atagtgccgt
    27241 ctgttggatc ttcttttgtt tctccccttc ttttctgcta tagtaaagaa gcaagatgat
    27301 tgtaaaggag acgaaatgga tgatcgatag tcctgattat tgtacatgta ataacaacaa
    27361 aaatatccat acagaattta atgaccaagg aagcttgagc atatgcgaca actgtcacaa
    27421 actagtcaaa gattcattta aaacatttga atcttatcct gttcaaaatt atgtaaaaag
    27481 tagaagaaga taaacaaatc caagcaaaac tcactatggc tgatttttat gaacttcaaa
    27541 ctcagcttct tcctttgatc aagcttcatc agtaaaacaa acagtggatc atttcagttt
    27601 acaaatcaaa gagtaaagat ttatttattt caaatatttg aatataaaat aaccaaacga
    27661 tagaaaggct tattctacat cacgtagtaa tttttctttc ccgtcgtttg gttttttatt
    27721 tttagcctaa ttcttgacct tttgcatgct ggttatccgt aaaatatttt ccagcaggct
    27781 ttccttccaa ttcagctaat ttttcttgga tctgacggat cacctttttt gcatcttctg
    27841 gattttctac aaaatcgaat ttatccccat ccacttgtat tttaggacat acatcaaaat
    27901 cttcatacca ttgattatag cgggtgttca acgtttcata ataggtatat aacgtctcat
    27961 cgctttctag ctgttcatag tcacgcccac gttttttgat acgttctagc atcgtgtcca
    28021 aagaaacttt gatatggacc atcaaatcag gccgtttttt tggagcaaca tcatctaact
    28081 cgtttagcat cgtatctaat aagctatcgt actgctgtac ttcgatatcc gttacccgac
    28141 ctaaatcagc gtttagatgg aacaacaggc tatcttcata gatggatcgg tctagcacat
    28201 tgtcatcgtt cactaaagca tttttcattg ctaaaaatcg cttgttcaaa aagaagattt
    28261 gcaataaaaa agcgtactgc tcaggatttg aataaaagag cggcaatact tcgttatctt
    28321 cgacattttc ataaaatggt ttagaatcaa tctcttttgc aagcatatcc gtcaaactgc
    28381 tcttacctgc accaatcgtt cctgaaatca aaatcactga catacaaccc ttcctcttct
    28441 ataagtactc gcctacgtaa gtttcaacag gcaatgtttc aaaatcatat tcacgtacag
    28501 cttggtctga ttttaaatac gtatggagac tttgtgtaat catcaagttc gtaggtaccg
    28561 tctcttcttg tacaatgatc atcggttttt tcaacatagt tgccacacct aattcgtaag
    28621 ccgttcctgg atcgattgtt tgatgctcaa agtcaaggat agcaacaaca aattctgcat
    28681 ttgtcagttc ttccatatct ttttcgtata cttcctgcgc ccatccagcg ctgaatagtt
    28741 cataattgct ttcttggtga tgacgtggag agtagaaact tgtgactgtt ttgttttcct
    28801 ccaacgcttt ttcgatacga cttactcgat cgatttgctc ctctgaaaaa aatggtcctg
    28861 ctaaatatat ttgactcatt attttgcctc cttcaataat aactgatttt taatagatac
    28921 tgctcgtaat tcattgacca gttccaatgg attgttggaa aagattactt gatccaacca
    28981 ttttttatcc ataaaatcct cttttgcaaa agtttctaat aattgttgca agccgctgta
    29041 ataaccgcca atattcaata ttccgattgg cttgtcgggc gtcagaccga ttgctatcca
    29101 agaaagaagt tgtgagaatt cctccaatgt acctagacct ccagggaaaa cgaggacagc
    29161 atctcccttt tcaaataata atacctttct ttcatcgatc gtttctgtag gaataaatgt
    29221 agtaacatct tttccaggca attcagtttc aaaaagccca ttcggataga tacctgtgac
    29281 ttttccgtta ttttccagta ctgttttact aatcactccc ataatcccgg agtatgaacc
    29341 accgtaaacc agttcgattt cttcttgtgc catgtatttt cctaacgttt gcgcaataaa
    29401 tttgtaactt tctttattac caaaacggga accgcaaaaa acagtaagtt tcataaaaaa
    29461 acactcccta actcaaaagt ctatcttcat tctacacgtg tttttttaaa ataaaagact
    29521 agattttgta gttttttagt ggtatatagg atagacgcca ctatatatag tatttagaaa
    29581 aaaatcattt ttcagccatt ttatagataa aacaaaaata aataacgtgt tttcatcgat
    29641 atgaaatgac ttacttatag aagatactgg gatttcgtcc tatatgccaa taacgtgtat
    29701 tattttaaac aacaaatact tgtttctttt attaacgaaa aaatcatttt gttctcgtgt
    29761 tatgtttcac tgataaatga tgtttctcta aataaaaaag ccgacgaact aaacgatcaa
    29821 aatttgatca tttttgttca tcagcttctc ctaaaaatct ttttgttaac gataaatagc
    29881 tggatttgta aaaatatcac ttgaatcgtc actgctggaa gaaaattcag tgataaccgc
    29941 acctgttgcg cctgcctgga actagtgttt gatattgggc tcgaacgtgt actgatctct
    30001 agcatgaaga ataatttctt tttttactgt ataataactt tctttccttt ttggaatagt
    30061 acaggaaagt ttttttgttt cctttccttc gacataaggt ataccagacc ctttcgacaa
    30121 cgaaaggttc tcatttttcc ttcatcgtca tttcaaggag ggtgccgatg ctctggacag
    30181 tttcgatcgc tcctaaacca aaatctgtat attcgattct ttctaactct gattctttca
    30241 taccattcct gtctcaaggt acatctattg tacttttttc ttgtaatcca ttctgcctct
    30301 cctaactaat tgtcaaatca tcccaagata tgtcttcttc ctctttttct tcttggatga
    30361 tttctgcatt cggatctact ggttttttca ataataaaat ggttattcct gtgacaaaag
    30421 aaccagctaa caatgcacca atgaatgccc atggtctggt catcgtagcg actgcaaaca
    30481 ttcccgatgc cggaatacgg ctatctgcgc cccaaaacat gcttaatccg ccacctactg
    30541 tcccaccgac tcccgttgct atgacattgc gtgccaagtc gttcaatacg atagggaaac
    30601 atccctctgt gatctgacag atccccatag gaaaagcggt cttcaatgta tcgatttctt
    30661 gacgattgag tatattttta cgaatgattt tccctaagaa ataagcgatc gtcaagccga
    30721 atggggttac catcgaagct aaaatcaata cagtgattgg ttcatagatt ccttctgaaa
    30781 atcgtgccac acccccttat ccagaataaa tggtaatcca gaaacagccg tgtatctgcg
    30841 gtaataagcc taaccaaacg aaaaatatga gaagctattt ttgtttggct gttcttatta
    30901 cttgatgcag ggcagctttt tcacaacctc tttttttatt tatgtttcat aatcaatatg
    30961 gtaaggatgc agctccgtat ggtagaccgc ctccgaatat tcaatcattt ccccaatttg
    31021 cgtagacgat ttccgtatcc gtttgatgcc gatctgtgcg tctgttttca gaattccttg
    31081 ttcttcttct gttaaaaata ctgccgagaa atcatcagaa aatgagtcaa tagtatatcc
    31141 ttttttcgtc agcaaacgat acaaagattc tttgccaaat tcttctctgc tgaattgcat
    31201 catttcttgt ggaagataat gaacaaaata aatataaggc tgattgttca aataatataa
    31261 gcgcttaaaa caaacagctt gctcaccgaa aaaggaaaac aaaggatctt ccttctttat
    31321 atggaccaat tgcaaatcca gcgtttcttt ccggacttca tatcgggagt tctccaagat
    31381 ttgcgtaaag cttgccgctt tggataatcg attgtaagga cgattgctta gaaccgtcgt
    31441 cccacgacca cttttctttg cgacatattc atctgatgcc agcagttcga ttgcctttcg
    31501 gacagtgatt ttgctgactt gaaacagttc ttctaattca ctttctgtcg gcaacatcga
    31561 accgactgga tattttcctg agaaaatatc ttctttaatt ttatctgcga cttccaagta
    31621 tagtacacgt gtccttttca taacgtcacc ctttgcttta ctattactaa aagaatagca
    31681 cataaaaaat aaaaaaagaa cacaaatcac atgtgagaag tgtgttcttt ttcattcagc
    31741 tgctttaatt acaagtttac gccatttgag gcaattactt ctttatacca atcaaaagat
    31801 tttttctttg atcgattcag tgtcccattt ccttcatcgt ctagatccac atagataaag
    31861 ccgtaacgtt tactcatttc tcctgttgat gcactgacaa gatcgataca tccccaaggc
    31921 gtatagccca tcaaatctac accgtctgct actgcattag ccatcgcttc gatatgacga
    31981 cgtaaataat cgatccgata atcatcaata atcgtgccat cctcttccat atgatcaatg
    32041 gctccaagac cgttttcaac aatgaataat ggtttctggt aacgattgta taattcattc
    32101 aatgcgattc tcagcccttc tggatcgatc tgccagcccc attcacttgc ctcaagaaac
    32161 ggatttttta ctcctcccag caagttccct tctgaagttg ctgcttgtgg atcagtctca
    32221 ttgattgccg tagacatata ataactaaat ccgatgtagt ccactggata ttcttttagc
    32281 aactggaagt ctttttccgt ttgctctaat ttttccggat cgactccata ttttttatgg
    32341 gtacgcgctg tgtatgcagg gtattctcca cgtacttgga catccgtgca gaaaaaattg
    32401 aattcttggt tttggatcat tgttgctgcc tgattgactg gattggcatc gatgctgtaa
    32461 gttgttgcat agataatcat gcagccgatt tggatatccg aacgcaattc gtggccgatt
    32521 tttacggctt tgctacttgc aacgaattga ttatgccatg cttggaaaat attttggtac
    32581 tctcctgctc cattgctttt tactaatcct tgacttaaag ctggaaagtg aaaggccgaa
    32641 ttgatttcat tgaaagtcat ccaatatttg actttactgc tgtatctctc taatactgtc
    32701 tgagcaaatc gttcatagaa gtcgatcagt tttcgatttt tccagccacc gtattctttt
    32761 gccaaatgaa gaggcatttc gtaatgagaa atcgtgatca caggttcaat atcatatttt
    32821 aagcactcat caatcagctg atcataaaat tctaatcccg cttcgttagg agtaccttcg
    32881 tctccatttg gaaaaattcg tgtccaggca atcgaaaaac gataacattt gaatcccatt
    32941 tccgcaaaca aggcaagatc ttctttgaaa cgatcgtaat gatcgattcc tcgatgattc
    33001 gggtaaatat atttttcttg atcaatcgtc cagtcaaatt cttcactgcc gataatcgca
    33061 aagcgctgct tacctccagg catagcatct gcaacggata gtccttttcc gtctcgatca
    33121 taagcccctt ctaattgatt tggcagcagt tgctccaccc cataaaaatt tttctgaaaa
    33181 acgtgattgc atcctgattt cctccttatt ttacaattgc cagaacatct tcgtttgcaa
    33241 taatctcttt ttggtctaat tcaagtatat cggcaaatgc atcagtattc gtaatgacaa
    33301 ctggagtgat tacgctatag ccagctgctc taattgcttc gatgtcaaaa cgaatcaata
    33361 aatctcctgc tttgacgaga tccccttgtt tgactaagat ctcaaagcca ttcccattta
    33421 attctactgt atccatcccg atatgaatca aaatctccgc tccgtcagtc gttgtgatcc
    33481 ctacagcatg tccagttgga aaaatagtcg tgatctctcc gtctgcaggt gcaactagtt
    33541 ctcctacttc tggatcaata gcgatacctt ttcccatcac gccagaagaa aaaacttggt
    33601 ctggtacttc actcaatggc agtactttac ccgttaaagg actttttaag gtatgccgtg
    33661 ctgaagtaat cggttttcct gcattcgcat gtttgttttc taattgattg tcttgtgttt
    33721 gttcgtcaaa tcctaaaatc aatgtaccta cgaatgcaag aacaaaagca attcctgtag
    33781 ctattactgc tactgtcaca tttgactcta caccatccac cgtattaatg aaagtcggaa
    33841 tcgtcaataa gctgaccaaa ctgctggaga aagcttttac tccggaaaat ccgataatag
    33901 ctccaccaat acctccagaa atacaagcgg caatgaatgg tttcttcaaa ggtaatgtca
    33961 caccatacac agttggttca gtgattccaa ataacgaagt cactgtagaa gaaatcccta
    34021 atgctcgaag tttcgtatct tttgttcgca atgctacagc taaagcagcc ccaccttgtg
    34081 ccaagatggc tggaagaagc attggcatca atacatcaaa cccatattgt tcgatattca
    34141 aaaacatgat cggtacgaat ccccaatgca tgccgaacat cacgaatact tgccataaac
    34201 ttcccatgat tagacctgct acgattggac taaatccata aatcgagttg aagagaccgc
    34261 ctaaagcatt accggcaacc gtcccgattg gtcctaaagc aagaaatgtt aatggaacca
    34321 tcactactaa aacgacaagc ggaactaaaa tcatttgcag aaattgcgga atcacttttt
    34381 ttacgaatgg ctctaattta ctttgaaccc atacggctag aatgattggt atgacagaag
    34441 aagtataacc agatggtgaa agaatcactg ggatcccaaa gaaactgata gcttctcccg
    34501 caccagcaac tgctgtgata gctggataca caagtgccat agcaattgct actgctaaaa
    34561 actggttggc tttgaacttt ttagctgctg taaaagcaag catgacaggt aagaaggtaa
    34621 agacaccatc tgctgcagca aacaatattt gataagtacc gctatcagct gtcagccagc
    34681 ccatcaccgt tgccaatgat aagaatcctt tcaatacccc ggcggctgcc atcgccccta
    34741 gaaaaggtgt aaatatacta gagataatat cgatcagacg attcaaaata tttttggact
    34801 cttcttttcc atcctccgaa actgcaagac cttcctcatc cacgatcgat tgataaacat
    34861 ctgctacatt actgccaatc actacttgat actgaccgcc actttgtacg acttggatca
    34921 cgtccgggtc ttcttttaac ttttgcgtat ctgctaaaga ttcatctttt aatctgaatc
    34981 gcaaccgcgt agcacaatgt actaaacttt tgacattctt ttgtcctcct accgcttccc
    35041 atacacgacg accaactgct tgattatcca ttgttttttc cttctttctt ttttatttaa
    35101 aaaataaaaa cccagattga aaaaaacagt cacaaacatt cgtgaaccta ttttttcaat
    35161 ccaggttttg cctgccatac agtaacaatc cttatgattg gatgcttttt ttctcactta
    35221 ctactctttg aatatgaatc gttaaataaa tctgctctgc gatccccatt tcctgttttt
    35281 gcgtttgtcg aagatactca ttgatccgtt cgacacaatg aaacgctttt ggatactttc
    35341 cttgaactaa tgcgtagaga aattcatctt gctcgtcaga tccttcccct ttgagataac
    35401 gctgggcaaa aaactgcaga tgagtaatga tacgctgata attcaaagat tcttcatcga
    35461 acacgatgcc gaagaattta ctgatgatac tcagtatatc tcttaccatt gtggtagcgg
    35521 tcatcgtcac ttgcatgtct tcgtttcctt gttggctatt cacaaaatga aaggcaataa
    35581 aaccggcttc atcctcagaa agttccacac ccgtcttttg tttcacgaac aaaagagcct
    35641 ctttcgctgc ttgatattct ttcggataaa atttttttgt ttcaaataat aatggattag
    35701 gcagttggat attttctttt gctcgtgtga tcgcataatg aagatgatcg gtcaatgtca
    35761 gataaatatt aggcgaaaat tcaactttta gtttatcttc agccagttcg actacttgtt
    35821 tgacccattc gatctcctct gccggaatat cagccatcag ctgctggaat tggtttttag
    35881 caaaagaatc tcttaaaaca aattcttttt ggaccgcttc tggcgaaatc tcgtccccaa
    35941 tctttttttg aaaagctagt ccttttccca tacaaacgac ttcttccccg aatccatttt
    36001 tcgaaatgac gacattgtta ttcaaaattt tatcaatttt cattttgctt cgccctctca
    36061 agaaaaataa aaaaacctag aattcgccta ctgtttctta gctgaattct ggttttgcct
    36121 gccgtacagt aacaatccat ttcttattca aaatcatcat accatcgaat ttttatttat
    36181 gcaagccttt tcatataaaa aataaaaaaa ctggaacaca agtctatcta gaaaacaacc
    36241 aaatcagaga tgcacctctt tgcgtttctc tttttttcag caaattggtt tttccttatc
    36301 gattcatatc ctttggctgt ttttaatctg taacgactta tgtcccagta tcctaaaatg
    36361 tttttgtctc tagattgaaa gcagatctca tatcatctgt cgcatctttt atcgatgtaa
    36421 cactttccag ttctccttgt acaactagtc gcgtgacggc gtccatgtcg ccacaagtaa
    36481 ttagtgtgac aatttctttt ccctcgactt cattcagtaa ttgggtatct gtaggagcaa
    36541 ctttttcttt aaaaaatgtt ttgtatgtat acacattttc taaatctgtc aaatagatct
    36601 tggcacccat ctctaaattt tctagcggtg taaacagcaa ttcagggttc gttgcacgat
    36661 ggcttgctaa ggcataattt ccttttccca tttcttgatc tggagataat gttcctgctc
    36721 cgtaaagtag tgacgtatta tccaagcctt tgaaaaccgg taaattgatt gaaactgaag
    36781 ggactgcgat actagcaatc actggtagat ctgttcctct catttgcgac ctcatgaccc
    36841 cttctgtcgt cattggttct accgcatcaa agtcaaaact gacatcttta tcgttattct
    36901 ttttcagatc ttcttttgtt acattcgcta tagcatattt atctcctgtc tctctgacaa
    36961 aataatcctt gatctgttca ttgaaaatca aagctagtcc tactaataac aagaggaaca
    37021 agaggatatt gactagccat ctttttgctt ttcctttttt tttcattttc tctccctcca
    37081 gactcatttt actgtttttc ttttgctctt tccaacagcc gaatgacaca tttctacaac
    37141 tctgtgtatt tttttcgtac acctgcgctt ttttctacag gatatttcaa attatttttg
    37201 atcaattttt cttcaatgat ctcatctaga tccaggtgaa ggttgtctgc catcatgtat
    37261 gaatagatca atacatctgc cagttcttct ttgattcgtt ctaattgtgt ttcttttact
    37321 tcttccggcg ttttccattg aaaaagttct aacaattcag atgcttccaa agaaatagag
    37381 atagccaaat ctttttcgtt atgaaattgt cgccaattac gttcatctct aaactggttg
    37441 actttttcca tactattcat ttgcttgcct tcttccaatc acttcttact tgattaatca
    37501 taccattttt ttacataaaa aatagatgat gcttttaaaa aaactcctgt tttcttttat
    37561 ttaaaataaa tgtcatagaa aatcaataat ttaggtagcc accatgtgta tgcagtagcg
    37621 tgtcttcttc ccttgaggct ttttgttttt cgatacgttc ttcttcccaa acagacaacg
    37681 ctactagaat ctctcttaat gattttcctt cttcggtgag cgagtactct actttaggcg
    37741 ggacttggtt ataggctttt cgatggatac tttcatcttg ttctaactct cttaactgct
    37801 gggtcagcat tttttttgtg atcgtaggga tttgcttgct tctccacgcc taaaataagc
    37861 gatattgctc ttccctttat ctggtgtaag caaagcagtt agcattttga cgatcgtggg
    37921 ttccgctttt cacttcttat ctacttagta tcatgaagta tactttcgta ctaatactaa
    37981 gtagcggaag tgtcaactac tttgtttaac tacatagcaa aagaaacaga agggtgacaa
    38041 cggtcatcac gcttctgttt cttttgaata tgctgtgttg ttgtctctat ctccgtgtag
    38101 actttcctca aacttatcct ttgacagtaa gtcagtaggc tgatttgctc tttctagatg
    38161 ccagatacat ttctacaaaa aaatagtgat tctgttttga aaattcgatt tttagttctg
    38221 cattttcgta aacatccaac atttttttcg cactgtatag acctaacccg ccattttttt
    38281 tagaggtttt tcctcttttg accatctccg atagcgtcaa attcgttgga tttgccttgt
    38341 tcgctatact aaaacgtgat ccctcttttt cttccagcag attgatcgta atcggactct
    38401 gatcggctac acgatgatcg aatgcgttag aaataaaaat agataaacag cgaataaaaa
    38461 caaccagatc aatcgggatt gttttcactt cgacaggaat aactacttgg atcgggattt
    38521 tctccgattc tgctttttct agaaatttta aaaagacacc cctgacagct ggggatacaa
    38581 tatttgttag ctgttgtatt tgcggttttt caaaaatagc tgcagaatga tcttctaata
    38641 tttctaaaaa ttccaacgtt tcttttttat tttcctgaag agtaattttt aatgaaaaca
    38701 gtagactttt ataatcatgt ttgaattcct ctagatgatg gtaatattct tcatttattt
    38761 gatacagttg aagcgattcc tgatgttgtc tttcttttac ttggaaactg atcaacataa
    38821 tggaaaaaaa caaagaaaaa aaactgatga ctatcgacaa aagagataga agcagataat
    38881 tagatgagcg gaagtgaaca cttcccaata ccaagtaaat cacgccccag cttaataaaa
    38941 tacaaatacc tccaaaatag tgttcagttg gataagtaaa aagcaagttg agaaatctcg
    39001 tctgtttgtc tatacttttt actaatagat agaaaataaa tgcgataagt agtgcaaaaa
    39061 aacttgctgt tccaagatgt ctctttccta aataatccat cagatcaaaa accagaaaaa
    39121 agctgagtcc agtgatagca aaaaaaagat tactgatcaa acagctgata aacaggtttt
    39181 tcgtagtaaa ataaaaaaga aacatcaata ataagccaac taggtaagga aagctcactt
    39241 tagggatagg aagtaaaagt gtcaccacca tcaaagctat acaaccaaag ctgtttttta
    39301 ctagcagttg tttcgaaaag aataaataga tacctaaatc taaaatcaaa gtaaaggtca
    39361 aataaagtgt cactgttgcg accatcttat tcctccattg ttttgtttca aaatgtacac
    39421 atattttttt aataggagcc tgcatatgaa aaagtatttt atcatagaag ataaccagtt
    39481 tcacagcgaa tggatcatca gagaattggt caatcatcat atcgagaata tcgtgcagct
    39541 cacttctatc tctcaaatca atcagttgat ccagttgggc actattgata atcacgatgt
    39601 tttctttatc gatatcgact tgaagcaatc actcacaggt attgatgtcg ccgaacaaat
    39661 acgtaaaaaa aatgcacata gtaatattgt ttttttcacc gcttatacga attttgcagt
    39721 agagatcatc aatcggaaaa tccttccgat tggatatatc agaaaagaca ggaatttatc
    39781 tgaacaaatt cgtcaagtgc tagaacagat caattggaaa gaacagcaga tcgtaaatgt
    39841 cgataaaatc tttattgatc aaaaaggtgg aagtctcgtc ctgtatcctc gggaaatttt
    39901 atatattgaa agtatcaaag gtttgaaaaa ccaagttatg gtcaaaacaa ctacagaaga
    39961 taaattagtg aatacttctt taaaacaatt gaagacagag ttagaaaagt atgcttactt
    40021 tttactttta aaatcttact gtatcaactt atcgcaattg cagaaaattg attctgctca
    40081 ttatgtgtta gaatttttca acggtgactc cttactcgtt ggtcgaaaga tctttgaaaa
    40141 gacaaaggaa cgtttccatg acttccaaaa aactgcttcg agttgatgaa taagagctga
    40201 gacgtaagca tagcagattt cagggagtgg gccttgaatc ggctccactc cctgaaatcg
    40261 ttgatatgat tttacgcttc ctcttctgta ggagcatctg ttaacgacca tgtgaatgtt
    40321 gaaacgtagt tgtctacagc ataattggat acaggaacaa ataattccac tgattgtctc
    40381 ccttgttcca cattctctcc taatgaataa atccatgtgc caatcccttc atttgctcct
    40441 gcagttacta gatctactgc ctgatctgct gggatttcga ttccttcagc gccagttcca
    40501 gaaacggtag atggcattcc actgctatta gttgcgctat ttcgaatcac ggcgtttttg
    40561 aatttcacct ttgaaccagt tagtttattc gtatcagatg ttgtaccaat aaattctgtt
    40621 cgtttgactg ataatttcca accggcataa tttccgcttt tatccgttac ttgtacgaaa
    40681 ttctgtactt gtgtttgtgc tccagtactg tccgttccgc tttgtaatgc agcatatact
    40741 gtttttgctg tacctaactt gattgttcca aaatcaagat ctggagcttg gtcaatcgtc
    40801 agtaatccgg atgttccctg atttggttcg tcaggtgtaa aaggagtatc aggatcattt
    40861 ggatcaacag gaggaactgg aacaacgtct tcaggatttg cagcatctgg tttggtcaca
    40921 gaaatcgttc cttctgtagt ggctgagctc ttattctcag caaaaacact ttgtgtacat
    40981 aataatagac ttccagctag aacggtactt aatgcaattg tttttttcat ttctttttcc
    41041 ttctttcttt taaaataaat aatccagcaa ataagccaat aagaatgact ccaacaagta
    41101 tcagccatcg ccagtcaaat gtttctggct gattttttaa atcaatatcc ttttcattca
    41161 attggtccgc tgcatcatca gttatttcaa aatcggtatg gagattccag cgtttttctt
    41221 tccaagcacc cttcacaacc gcttgataat gtcccggagc taattttttt ccttctaatg
    41281 ggacaagtaa atcaaaattt gtattgggtg ctacatctat tttttctttt tttattgaaa
    41341 ggtaaggctc ttttgtttct tttttgtaga tttcaaccga tgtagtcaag ccgaacatat
    41401 aagaagcatt tggattttga agattcgcct taatcacatt tcttccatcg ctttgatccg
    41461 cataagcttt ttttaatttc aaatctgggg aagactcttt ttcgctattt caaatcaaga
    41521 ttgctttcac ttgagaaaac tgattgacga caccaactgt acttttgtta gaaacgttct
    41581 cttttttttc ttgaaacgtg atccctcctg cgaccacacc agccagctct ttttctggcg
    41641 ctttcagtga aagtgtctca gtgaccgcac tttgaggagg aacagttatt tctcccactg
    41701 tttttgctaa gtttttcata tcataactta atgtttcatc aaatttactt tttgattctc
    41761 catattcgat cacaccgttt gaattcgtcg tagcggagtg gatcaatgtc tcaactgtta
    41821 ctgatttatc tgttcggtta aagaccgtgt aggggatttc ctgtgttttc ccaggctcca
    41881 tccttacatt tatatatgtt ttgttcttat caatctgatt agccggtaat tcaaaatcta
    41941 ccgcaaaatt gaattcggag gcatggacag gtgtctgcca aaggatgaat ccaaggagaa
    42001 ggatcataag taaagagcag ttgtttcgat gacttttatt ccatattcga ttcatcaatc
    42061 atcctccttg atctttattc tgtcggcgca tctgctaatg tccatgttat ctctgctgag
    42121 taattaccag ctatctgatt ttctttggtt aagacaagtt taaacgcccg accgttattt
    42181 aaatattctg aataatctgc ttgcacattc gttgaatttt gtcctctgac aatttccagt
    42241 tcttcttcat tcactaattg atactcctct cctttcttga aatataggac atcctgcata
    42301 gaaaatcctg catcatttgt gaaaggctga gataatttta tcgttaagat ccacggattt
    42361 ttcgtttctc gctgatcata aatccataat ttttcctgta tatccatttg gccaaatgct
    42421 tcttgtgtca aaccagttgc tttgatctga ccaaaatcga gtttggaagg ggcaagaaat
    42481 gagagaccac cttctactac gatcttcgta gcaggtgcaa aaggcggggc atcatgataa
    42541 acaactggcg tatcacttgg attgtgattc ccaatttcat cgttggtact tggcttgttc
    42601 tgcacaccct tagcagtagc ttctcctgct tggtcgttta atacaatttc taatacatct
    42661 cctgcaaaaa gttgattttc tgggatagaa agaacaaatt cccctgtatc atcaatagtt
    42721 gtttctgaca aaacagcttg attttttttc aatgaaacca aggctcctgc ttcacctgta
    42781 cctgtgatcg tgcgagaagc tgcattgatc aatgtggtac ttaaattagc aggttcagga
    42841 ggaatcacat cgactgtcgt tttggcagag tccagttctg tcacttcttg gccacctctt
    42901 acttttttag cagcaacaac ttgcacttga tcctccgttt ttaatctctc atcattgggt
    42961 acttgaactt cgaacaagcc gccttgttcg ccttctcccc atgggttata tcctgcccct
    43021 tcattttcat ctgtttgtcc ttgcgtgaga gcagtaattt ctacagatga tttcgtcgta
    43081 tctgcgtaag taatacgtaa agtcacttct acttcgcctg tccaagcatc tcttggcttt
    43141 gcctcgacac cttcgggaac aacgacatgc ccatagattt ttttatctgc attcgttggc
    43201 actcttaagg attcaatcat cgggagctga ttattggcac tgattcgatt ataatttttc
    43261 attccggcac ctgtctgagc aaattcattt gttaaacctg cactagggct tgatacgaaa
    43321 ttgcctaagt cggtcccatt gatcgataag tctgtcatat cagaaaaata atccgggtct
    43381 ttttcaaagt tatcgaatgt tgcgcctgtt tttcgccata aagcgatttc tgaatgggcg
    43441 atctttaaag aagaatctcc atttccttgg aatacccagc cgcctatgcc attggtctcg
    43501 cttccaatcc gtttgttttg gaaatcaaaa taggtaggag attctaagtc cacattcaac
    43561 acatccccac tgatgatgcc ggtcttatct tcccctgttt tcccgaccat gactaaataa
    43621 gttttttcac ctgccgtaaa atttaaatca atatctccag ttgtatctac agttgctccg
    43681 gaatctgcgc gtatatcgat atttgatttt tctccagtga ctgtaaaatc agctgaacct
    43741 ggactttcta gaaaaccaga agcgtcataa aattggatcg cttgatttcc ttgattgagt
    43801 ctgttcacgt aagatttgcc atcacctgta tttcttaccc tcaatgagcc tccattggtt
    43861 actgtcagct tttgcgtacc attctcaaaa cgaactgcgc tggaacgccc actctgctta
    43921 tcgatgtcga taactgatcc ggctccttct acgatcaaag aaaggccttt tcctacaaaa
    43981 cgcatcccat tgttcccggg ttgatcgtca tctccagcca ttttgaccga gatttgtcca
    44041 ccacttgata catggatttg actagaatct ccttgcaagc gaaatccgcc cgtagttgct
    44101 gtattgatgg tgattttccc accattcgat acagtgactt tcgatcctga acctctcatt
    44161 tggatgattc cgcgattgtt gtcattggta atattgatct ttgtatttac cgaaaattcg
    44221 cttcccgaac cactgacttc aaacatgaca ttaccaggta gcgtatcgac tgcctctcct
    44281 tcatcgctaa cgccatctgc ccgatcataa tcaagagaga cctttgaacc gcttaagata
    44341 tggattcctg gcgctgtttt tccactacca gtctcatctc ctgaatctag aaaaccgtag
    44401 aatttcccta gatacggtcc ataaagttga ctaccattga tcacattcaa ttgatagctt
    44461 ctacaaaaat aggctttacc cggagcggca ttcagtcctt ccttcactgg ttggacatcc
    44521 aacacaccgg aaacaccatc taatgtgaca gttgcacgag gagcgtaaat cagtcctaat
    44581 ttggacccat catacaaatc aagtgtcccg gtaaatttta tttctcccgt aaaatgatat
    44641 ctgcttcccc aaaaatcggt catataagca atgataatgg catttccatc gatatttggt
    44701 gtcaatccac ctggatgtgc agctgttcct ttaaaattct ggaactcgat cgactgaggt
    44761 atctcattga tataaatatg gtgtgtgccg aaattgtgag cgaatccacc aaaatcaata
    44821 acgatatctc gtttgatctc taattccctg tctaaagtca aaggctgaat cagtcggatc
    44881 ttagttactg attcgtctgc gagaagctgc gccagttctt ctgttgtggc agcttcgctg
    44941 tacccatccg ctgaaacagc tcttgccagt gccgcttcac tgctatcaga cgtttgttca
    45001 gctacttctg aggtctcact tgtcttattt tcttcttgcc ttttattagt agaagcctca
    45061 ctttgagatt ctgtagtttc agaagtaatc gattcttctg aaaaagtagt cttgtcaaaa
    45121 ctttgattct ctgattgcgt tgattcgttt gttttctcta catcggcaaa aacggatgtc
    45181 accatcaaga gagggaagac aaacaaaatc gacgcaatca gcttttttac acattgattc
    45241 attctccacc atcctctctg acgttttgac aattttattt tatcgtttta atctatttcc
    45301 aattgtactt tcatatttaa aatatgtatt tttatggaaa aatttttcta ttaggtgtaa
    45361 atttcttttt tgtacaaaaa aaaggctgtg acaaaagtct tgtcacagtc ccttatcccg
    45421 aacaagcggt gttctcccgc caactcctcg gtcacaacct ccattttaac aataaacctg
    45481 taaatgtgag ggcaatactt tgattgtcac aggtaattta tccccttcat ctccatcaac
    45541 attcgtcgtc aattcttcct catcagctaa tgacacaact aattgctcac aagtaaggta
    45601 ggctagattt ttcgtagatt catctactcc ttttaatagg tctggcaatg ttttaagcgt
    45661 atcgatcaaa gaagaatctt ttaaataaac caaatggagc ttaccatcat ccacttttgc
    45721 atttggaagt aatgtttcaa aaccgccgac tgagttagtt agtcctatca gcaaggtact
    45781 gctctcaatt tcttccttct ttccatcaac ttctacgtga aacgagtagg attgtgtgga
    45841 agctaactgt ttgattcctg acatgaaata agctagtttt ccaaatttcg tcttcttctc
    45901 cgcatctaca tcattgattg attcagggat agagccaatt gcgacgacat tcataaaata
    45961 gtcgtcattt atttttccaa tatccaatgg cttgactgat tcaatcgaaa aatgattgat
    46021 cgcttcctca ggttctagcg gtatccctaa tgctcgagcc aagtcattca ccgtacccaa
    46081 tgggaaaaat ccgaaatttg gccgatgttc ttgttcagcg attccactga ttccttcgtt
    46141 gactgttcca tctccgccca tgacaaacac actatgatac ccttccgtag ccgcttcgcg
    46201 agtaaagttt tttgcatccc ctgctttttt tgtatgcaag acgaccactt catcaaacac
    46261 cgattccaat tttgctatcg ctaattgctc aaattccttt gcttgttcac cgcctgaact
    46321 ggggtttacc actaataaaa cttttttcat cactttcttt cccttctgat tgatttcttt
    46381 aatataacga tagcataaag aaaaaaatta ggctgtgatg aagtactgtt catgaaacat
    46441 tcatttattt tttgacaaga taaaacatcc atactatgaa actgaggaaa attaaaacaa
    46501 tgatatagga aataaaagaa aatgataggc attgtatacc taataaagta aaaatcttag
    46561 gtggcagata aaaacacaaa aatagcaaga gaatgtaata gcgtttcttc cactttttgt
    46621 tatcagacct tatagcgatc agaggaatac caaatgcata actgaaaaac tcttgatgta
    46681 ctgttaatat gtcacggcct tgaataataa atgcgacaat ccccgctata attagtgtgc
    46741 ctaacaccaa aacggaaaat tgatgaatat attttatata caaatgatcc attgtacttc
    46801 ctgccttttt atttgtgaga aaaacaaatc cgtatacgtg aataacttct agaaataaaa
    46861 gaaatttgca aaaccactcc atttatctac ttctacgtgc attttttgat attgt
//
LOCUS       DARBDN010000012        45007 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000012 DARBDN010000000
VERSION     DARBDN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.012"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            212..604
                     /locus_tag="SCH06_000712"
     CDS             212..604
                     /locus_tag="SCH06_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEG1077311.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="SCH06_000713"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="SCH06_000713"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEG1077312.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="SCH06_000714"
     CDS             3165..4775
                     /locus_tag="SCH06_000714"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEG1077313.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="SCH06_000715"
     CDS             5067..5936
                     /locus_tag="SCH06_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEG1077314.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="SCH06_000716"
     CDS             6101..7372
                     /locus_tag="SCH06_000716"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEG1077315.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="SCH06_000717"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="SCH06_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HEG1077316.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="SCH06_000718"
     CDS             8763..9026
                     /locus_tag="SCH06_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEG1077317.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="SCH06_000719"
     CDS             9471..9920
                     /locus_tag="SCH06_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1077318.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="SCH06_000720"
     CDS             9977..11395
                     /locus_tag="SCH06_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1077319.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="SCH06_000721"
     CDS             11395..12255
                     /locus_tag="SCH06_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HEG1077320.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="SCH06_000722"
     CDS             12429..13202
                     /locus_tag="SCH06_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEG1077321.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="SCH06_000723"
     CDS             13349..13714
                     /locus_tag="SCH06_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HEG1077322.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="SCH06_000724"
     CDS             complement(13862..15070)
                     /locus_tag="SCH06_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077323.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="SCH06_000725"
     CDS             complement(15089..15367)
                     /locus_tag="SCH06_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077324.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="SCH06_000726"
     CDS             15521..16216
                     /locus_tag="SCH06_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEG1077325.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="SCH06_000727"
     CDS             complement(16658..17455)
                     /locus_tag="SCH06_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HEG1077326.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="SCH06_000728"
     CDS             complement(17452..18636)
                     /locus_tag="SCH06_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEG1077327.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="SCH06_000729"
     CDS             complement(18661..19908)
                     /locus_tag="SCH06_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEG1077328.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="SCH06_000730"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="SCH06_000730"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEG1077329.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="SCH06_000731"
     CDS             21888..22202
                     /locus_tag="SCH06_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEG1077330.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="SCH06_000732"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="SCH06_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEG1077331.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="SCH06_000733"
     CDS             22887..23531
                     /locus_tag="SCH06_000733"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEG1077332.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="SCH06_000734"
     CDS             23546..23875
                     /locus_tag="SCH06_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HEG1077333.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="SCH06_000735"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="SCH06_000735"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEG1077334.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="SCH06_000736"
     CDS             24863..25687
                     /locus_tag="SCH06_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HEG1077335.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="SCH06_000737"
     CDS             25680..26027
                     /locus_tag="SCH06_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEG1077336.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="SCH06_000738"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="SCH06_000738"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEG1077337.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="SCH06_000739"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="SCH06_000739"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEG1077338.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SCH06_000740"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="SCH06_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEG1077339.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYAFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SCH06_000741"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="SCH06_000741"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEG1077340.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGSFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="SCH06_000742"
     CDS             31657..32451
                     /locus_tag="SCH06_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077341.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="SCH06_000743"
     CDS             32441..34483
                     /locus_tag="SCH06_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077342.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="SCH06_000744"
     CDS             34764..34913
                     /locus_tag="SCH06_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEG1077343.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="SCH06_000745"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="SCH06_000745"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEG1077344.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="SCH06_000746"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="SCH06_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEG1077345.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="SCH06_000747"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="SCH06_000747"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEG1077346.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="SCH06_000748"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="SCH06_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEG1077347.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="SCH06_000749"
     CDS             39330..40412
                     /locus_tag="SCH06_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEG1077348.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="SCH06_000750"
     CDS             40412..41215
                     /locus_tag="SCH06_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEG1077349.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="SCH06_000751"
     CDS             41285..42025
                     /locus_tag="SCH06_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEG1077350.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="SCH06_000752"
     CDS             42036..43040
                     /locus_tag="SCH06_000752"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEG1077351.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="SCH06_000753"
     CDS             complement(43085..44929)
                     /locus_tag="SCH06_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077352.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14481 a         7842 c         9356 g        13328 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaactttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttttta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggcatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagaacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaat
//
LOCUS       DARBDN010000013        44939 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000013 DARBDN010000000
VERSION     DARBDN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.013"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(38..1189)
                     /locus_tag="SCH06_000754"
     CDS             complement(38..1189)
                     /locus_tag="SCH06_000754"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEG1077353.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="SCH06_000755"
     CDS             complement(1202..1639)
                     /locus_tag="SCH06_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1077354.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="SCH06_000756"
     CDS             complement(1654..3420)
                     /locus_tag="SCH06_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEG1077355.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="SCH06_000757"
     CDS             3684..4361
                     /locus_tag="SCH06_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077356.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="SCH06_000758"
     CDS             4364..5491
                     /locus_tag="SCH06_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077357.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="SCH06_000759"
     CDS             complement(5691..6131)
                     /locus_tag="SCH06_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1077358.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="SCH06_000760"
     CDS             complement(6142..8175)
                     /locus_tag="SCH06_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEG1077359.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="SCH06_000761"
     CDS             complement(8177..9880)
                     /locus_tag="SCH06_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1077360.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="SCH06_000762"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="SCH06_000762"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEG1077361.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="SCH06_000763"
     CDS             complement(10963..11988)
                     /locus_tag="SCH06_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEG1077362.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="SCH06_000764"
     CDS             complement(12197..13066)
                     /locus_tag="SCH06_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HEG1077363.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="SCH06_000765"
     CDS             complement(13525..15417)
                     /locus_tag="SCH06_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077364.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="SCH06_000766"
     CDS             complement(15414..17141)
                     /locus_tag="SCH06_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077365.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="SCH06_000767"
     CDS             complement(17157..17807)
                     /locus_tag="SCH06_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEG1077366.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="SCH06_000768"
     CDS             18011..18307
                     /locus_tag="SCH06_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEG1077367.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="SCH06_000769"
     CDS             18479..19099
                     /locus_tag="SCH06_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HEG1077368.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="SCH06_000770"
     CDS             complement(19191..20357)
                     /locus_tag="SCH06_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEG1077369.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="SCH06_000771"
     CDS             complement(20369..20722)
                     /locus_tag="SCH06_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEG1077370.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="SCH06_000772"
     CDS             20850..21872
                     /locus_tag="SCH06_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEG1077371.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="SCH06_000773"
     CDS             21891..22052
                     /locus_tag="SCH06_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077372.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="SCH06_000774"
     CDS             complement(22311..22745)
                     /locus_tag="SCH06_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077373.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="SCH06_000775"
     CDS             complement(22855..24714)
                     /locus_tag="SCH06_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEG1077374.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="SCH06_000776"
     CDS             complement(24832..25992)
                     /locus_tag="SCH06_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HEG1077375.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="SCH06_000777"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="SCH06_000777"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HEG1077376.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="SCH06_000778"
     CDS             complement(27739..28437)
                     /locus_tag="SCH06_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEG1077377.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="SCH06_000779"
     CDS             complement(28394..30055)
                     /locus_tag="SCH06_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HEG1077378.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="SCH06_000780"
     CDS             30273..31673
                     /locus_tag="SCH06_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HEG1077379.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="SCH06_000781"
     CDS             complement(31925..33004)
                     /locus_tag="SCH06_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1077380.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="SCH06_000782"
     CDS             complement(33090..34049)
                     /locus_tag="SCH06_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEG1077381.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="SCH06_000783"
     CDS             complement(34061..35572)
                     /locus_tag="SCH06_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEG1077382.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="SCH06_000784"
     CDS             complement(35594..36157)
                     /locus_tag="SCH06_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEG1077383.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="SCH06_000785"
     CDS             complement(36163..37026)
                     /locus_tag="SCH06_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1077384.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="SCH06_000786"
     CDS             complement(37040..37936)
                     /locus_tag="SCH06_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1077385.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="SCH06_000787"
     CDS             complement(38111..39400)
                     /locus_tag="SCH06_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1077386.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="SCH06_000788"
     CDS             complement(39372..40889)
                     /locus_tag="SCH06_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEG1077387.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="SCH06_000789"
     CDS             41087..41977
                     /locus_tag="SCH06_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEG1077388.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="SCH06_000790"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="SCH06_000790"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEG1077389.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="SCH06_000791"
     CDS             complement(42886..44358)
                     /locus_tag="SCH06_000791"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEG1077390.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
BASE COUNT        12989 a         9387 c         7783 g        14780 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata ttagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggatcaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgttttt
//
LOCUS       DARBDN010000014        43369 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000014 DARBDN010000000
VERSION     DARBDN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.014"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(8..2389)
                     /locus_tag="SCH06_000792"
     CDS             complement(8..2389)
                     /locus_tag="SCH06_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEG1077391.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2379..3026)
                     /gene="recU"
                     /locus_tag="SCH06_000793"
     CDS             complement(2379..3026)
                     /gene="recU"
                     /locus_tag="SCH06_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEG1077392.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3090..3629
                     /locus_tag="SCH06_000794"
     CDS             3090..3629
                     /locus_tag="SCH06_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEG1077393.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3719..4138
                     /gene="gpsB"
                     /locus_tag="SCH06_000795"
     CDS             3719..4138
                     /gene="gpsB"
                     /locus_tag="SCH06_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEG1077394.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYEAYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4160..4527
                     /gene="rnpB"
                     /locus_tag="SCH06_000796"
     ncRNA           4160..4527
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="SCH06_000796"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4736..5902
                     /locus_tag="SCH06_000797"
     CDS             4736..5902
                     /locus_tag="SCH06_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEG1077395.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            5948..7444
                     /locus_tag="SCH06_000798"
     CDS             5948..7444
                     /locus_tag="SCH06_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HEG1077396.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7525..8208
                     /locus_tag="SCH06_000799"
     CDS             7525..8208
                     /locus_tag="SCH06_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEG1077397.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            8853..10043
                     /locus_tag="SCH06_000800"
     CDS             8853..10043
                     /locus_tag="SCH06_000800"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HEG1077398.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10145..11098
                     /locus_tag="SCH06_000801"
     CDS             10145..11098
                     /locus_tag="SCH06_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HEG1077399.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11167..12516
                     /locus_tag="SCH06_000802"
     CDS             11167..12516
                     /locus_tag="SCH06_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1077400.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(12699..13022)
                     /locus_tag="SCH06_000803"
     CDS             complement(12699..13022)
                     /locus_tag="SCH06_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077401.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13151..14314
                     /locus_tag="SCH06_000804"
     CDS             13151..14314
                     /locus_tag="SCH06_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEG1077402.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14384..15733
                     /locus_tag="SCH06_000805"
     CDS             14384..15733
                     /locus_tag="SCH06_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEG1077403.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(15778..16209)
                     /locus_tag="SCH06_000806"
     CDS             complement(15778..16209)
                     /locus_tag="SCH06_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1077404.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16597..19239
                     /gene="alaS"
                     /locus_tag="SCH06_000807"
     CDS             16597..19239
                     /gene="alaS"
                     /locus_tag="SCH06_000807"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEG1077405.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19439..20035
                     /locus_tag="SCH06_000808"
     CDS             19439..20035
                     /locus_tag="SCH06_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEG1077406.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20157..21305
                     /locus_tag="SCH06_000809"
     CDS             20157..21305
                     /locus_tag="SCH06_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEG1077407.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21343..21756)
                     /locus_tag="SCH06_000810"
     CDS             complement(21343..21756)
                     /locus_tag="SCH06_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HEG1077408.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            21835..22266
                     /locus_tag="SCH06_000811"
     CDS             21835..22266
                     /locus_tag="SCH06_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEG1077409.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22365..22598)
                     /locus_tag="SCH06_000812"
     CDS             complement(22365..22598)
                     /locus_tag="SCH06_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HEG1077410.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            22781..24451
                     /locus_tag="SCH06_000813"
     CDS             22781..24451
                     /locus_tag="SCH06_000813"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEG1077411.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24598..24984
                     /locus_tag="SCH06_000814"
     CDS             24598..24984
                     /locus_tag="SCH06_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077412.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            24971..25669
                     /locus_tag="SCH06_000815"
     CDS             24971..25669
                     /locus_tag="SCH06_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEG1077413.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            25674..26138
                     /locus_tag="SCH06_000816"
     CDS             25674..26138
                     /locus_tag="SCH06_000816"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEG1077414.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26135..27046
                     /locus_tag="SCH06_000817"
     CDS             26135..27046
                     /locus_tag="SCH06_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEG1077415.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27281..27820
                     /gene="pyrR"
                     /locus_tag="SCH06_000818"
     CDS             27281..27820
                     /gene="pyrR"
                     /locus_tag="SCH06_000818"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEG1077416.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            27834..29117
                     /locus_tag="SCH06_000819"
     CDS             27834..29117
                     /locus_tag="SCH06_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEG1077417.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29130..30056
                     /locus_tag="SCH06_000820"
     CDS             29130..30056
                     /locus_tag="SCH06_000820"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEG1077418.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30075..31355
                     /locus_tag="SCH06_000821"
     CDS             30075..31355
                     /locus_tag="SCH06_000821"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEG1077419.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31360..32436
                     /gene="carA"
                     /locus_tag="SCH06_000822"
     CDS             31360..32436
                     /gene="carA"
                     /locus_tag="SCH06_000822"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEG1077420.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32441..35626
                     /gene="carB"
                     /locus_tag="SCH06_000823"
     CDS             32441..35626
                     /gene="carB"
                     /locus_tag="SCH06_000823"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEG1077421.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            35680..36456
                     /locus_tag="SCH06_000824"
     CDS             35680..36456
                     /locus_tag="SCH06_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEG1077422.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36453..37385
                     /locus_tag="SCH06_000825"
     CDS             36453..37385
                     /locus_tag="SCH06_000825"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEG1077423.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37382..38098
                     /gene="pyrF"
                     /locus_tag="SCH06_000826"
     CDS             37382..38098
                     /gene="pyrF"
                     /locus_tag="SCH06_000826"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEG1077424.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38105..38794
                     /locus_tag="SCH06_000827"
     CDS             38105..38794
                     /locus_tag="SCH06_000827"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEG1077425.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQIEARLMKIEK
                     SDLCLQNHQLE"
     gene            38767..39036
                     /locus_tag="SCH06_000828"
     CDS             38767..39036
                     /locus_tag="SCH06_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077426.1"
                     /translation="MSPESSIGIAKIQKLIARSIFSSGMKRNFYRDQFLIFLKFIFLR
                     LVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYLMI"
     gene            39074..39715
                     /locus_tag="SCH06_000829"
     CDS             39074..39715
                     /locus_tag="SCH06_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEG1077427.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            39758..40450
                     /locus_tag="SCH06_000830"
     CDS             39758..40450
                     /locus_tag="SCH06_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HEG1077428.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40447..41349
                     /locus_tag="SCH06_000831"
     CDS             40447..41349
                     /locus_tag="SCH06_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1077429.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41507..43213)
                     /gene="efbA"
                     /locus_tag="SCH06_000832"
     CDS             complement(41507..43213)
                     /gene="efbA"
                     /locus_tag="SCH06_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HEG1077430.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        13875 a         7663 c         9440 g        12391 t
ORIGIN      
        1 ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg tcatttgcag
       61 catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat gaagacggtg
      121 tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc tcgcttgttt
      181 ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta gtagagctag
      241 agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag ctggaagatg
      301 gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct ttgtagtaca
      361 gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt gtcacgttag
      421 ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac gattctgaag
      481 tgacaggtgt cattttttta ttgtaacctg tccacacgga aatcgaataa tttggcgtat
      541 agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt gcatactcgt
      601 catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg atttgcgcat
      661 tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata taagctgttt
      721 ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg tcttggaaga
      781 cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa gccgcatagg
      841 ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct tccgtattac
      901 tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt tttaagaaag
      961 aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca ttacgggata
     1021 agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag tttcctacag
     1081 gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca gtagaatatt
     1141 tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa ccaaaatcac
     1201 gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg tgacgtccgc
     1261 caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca acttgcatct
     1321 cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt ttcttttggg
     1381 cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc ttatctgttt
     1441 tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta gtattgtcat
     1501 cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct tgatcatatt
     1561 ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct cgtcttttct
     1621 tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc atcccagcaa
     1681 gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac atctcagaag
     1741 ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag taggtcaaga
     1801 tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct tgggccttgc
     1861 gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc aattgctgtg
     1921 tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca gaaccgatga
     1981 tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc gacacgatcg
     2041 catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt tctgcgccta
     2101 aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta gcgtctaatt
     2161 ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct acacctgcta
     2221 aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat aatccttttt
     2281 tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca ctctttttag
     2341 gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt cttgctttct
     2401 ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg aatccgcgga
     2461 gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg tagtgatttg
     2521 cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt caaataaaaa
     2581 cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg ttcgaggcat
     2641 gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga tgttttgttc
     2701 ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt atagtctgta
     2761 gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt aggatagtct
     2821 actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc gcgggaaaga
     2881 taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt gccgaattca
     2941 gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt ataataaggt
     3001 tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca ttatagcaaa
     3061 aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc tatgtgtctg
     3121 ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc caagttgtta
     3181 aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa tgggtacttg
     3241 tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa ttgaaagaag
     3301 aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt aataactgga
     3361 atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat gtcgaagctg
     3421 ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt tttatacttg
     3481 agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa acgaagtatt
     3541 tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg ctgatcagta
     3601 tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat caactttttt
     3661 cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag gtgtaaatat
     3721 ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa caaaaatgcg
     3781 cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag attatgaagc
     3841 ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg caaaagtagc
     3901 tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag aggcaccaaa
     3961 gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg aacgtgaagt
     4021 atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac ctaatccaaa
     4081 taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc aattttaatt
     4141 tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca ggctgaggaa
     4201 agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa accataagct
     4261 aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat gcttaagtat
     4321 ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga acgcggtaaa
     4381 cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa gaagaacagg
     4441 acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct ccctggaaaa
     4501 gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag gtcgtgacaa
     4561 aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa tacttcagat
     4621 gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat ttgagtaaaa
     4681 gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat tgtgtatgga
     4741 aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag cactggttgg
     4801 taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg cacgttttga
     4861 aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag atcgagtaaa
     4921 aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa acgtaaaagc
     4981 attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg gaaaatcgat
     5041 caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag caatcgttga
     5101 acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa ctggcgcaca
     5161 ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg atacgacagg
     5221 accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat tgaaagaaaa
     5281 catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat tttatgatcc
     5341 tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata atatcgcacc
     5401 aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag aaatcatgga
     5461 aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag atattactgg
     5521 ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag aaatcggatt
     5581 aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg ataaagaata
     5641 cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag aaactgttcg
     5701 gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga gtaaatatat
     5761 cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca aaaaaagaaa
     5821 attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc gtccgcctag
     5881 aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat gtttggagga
     5941 atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc ttctacaaca
     6001 agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag ctagtgcata
     6061 ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa tcggtccaaa
     6121 aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg aagttggaac
     6181 tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac cggaagatct
     6241 tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa aagctagaga
     6301 aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat taacaaaaca
     6361 gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc tgaatcaata
     6421 cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta aagaaggaat
     6481 tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag actttttaaa
     6541 tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg aacaacttgg
     6601 ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga ctggaattaa
     6661 tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa tggctgtttt
     6721 tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg ataaatatgc
     6781 gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat cgttgtttaa
     6841 cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt tctttcaaga
     6901 atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt cattgaacca
     6961 tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc tccatatcat
     7021 cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg ctgaactacc
     7081 tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa atgatgtgga
     7141 aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc cctcttatgc
     7201 attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa tagatgtgga
     7261 aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag agcatatcca
     7321 tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac atgaaccgct
     7381 taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat atcaggtaaa
     7441 ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt tttcagctat
     7501 ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga ttatagtatg
     7561 gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag agttgtcaag
     7621 ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac gcttgcagca
     7681 gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga ggcaaagcaa
     7741 cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc gatgattttt
     7801 tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga actatctctg
     7861 gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat cggcattttg
     7921 cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga actgtatccg
     7981 caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa tcatttttat
     8041 gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga agaagccaaa
     8101 cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg gtctattgac
     8161 gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg gaggttgtga
     8221 cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac ttctggaaca
     8281 ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga acaatttcaa
     8341 aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg gcaggagaac
     8401 accgtttatt cggaagaata ggactgtgac aagacttttg tcacagtcct tttttcgaat
     8461 tcaacaagta aaacttttaa gaaatattca gagagtaaaa ttaaaaattg ctgataaacg
     8521 aagatggaaa ttttatgtat ttttattggt ctatgcaata aataaattaa atattcagaa
     8581 tacaattgat tttaacgaaa gggcttctat caatggttgt gttgtattta tctgcccagg
     8641 tagagtaaaa tagatcatta tctaaaaggt aattgttcat actatataag tcatttgaaa
     8701 gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt ctcataatca gtgtaagcgt
     8761 tatcaaaaat atagcatact tgctttgtag atgaatgaca cgatatatgt ttggtatgtt
     8821 ctgcaagaca gatgaatatg gaggtggaga caatgtcttc caaagaacta acaatgtatt
     8881 tagagaaaga attggatcaa ctgaaagaaa aggggttata caatacgatc gacatactag
     8941 aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa gatgatcaat ctagcatcca
     9001 acaattatct tggatttgcc aatcgcgaag aattgaaaaa agcatgtatt gaagcaaccg
     9061 aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa tggttcgctg aaaatccatc
     9121 agcaattaga agaaaaaatc gcagaattca aagggacaga agcagcaatc gcctttcaat
     9181 ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat gacaaaagaa gatgctatct
     9241 tatcggatga attaaaccat gcatctatta ttgacggttg ccgcttatcc ggagcaaaaa
     9301 tcatccgaat taaacatcaa gatatgaaag accttgagaa aaaagcaaag gaagcgatag
     9361 aaagtaagaa atataaaaaa atcatgtata tcacagatgg tgttttctcc atggatggag
     9421 acattgcacg attgccggaa attattccga ttgttgaaaa atatggactg atcacctacg
     9481 tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc aggaaccgtc aagcattttg
     9541 gattaagcga caaaatcgat atgcaaatgg gcacgttatc gaaagctata ggtgttgttg
     9601 ggggttatgt agctggatcg aaaacactaa tcgactggtt gaaagctaga agtcggccat
     9661 tcctattttc tacttcgcta actccaggtg cagctgcagc tgcattggct tcgattactt
     9721 tgatgcaaga acatccggaa cttgtcgaaa aagtttggga aaatgctaat tattttaaag
     9781 aagaattgaa aaaagtaggc tataacatcg gtatgtctga aacacctatt actccagtca
     9841 ttttgggaga cgaaaaagtg actcagactt tctctaagaa gctgatcgaa catgggattt
     9901 atgctaaacc aatcgtttat ccaactgtgc ctcttgggac aggcaggatc agaaatatgc
     9961 cgactgcgga acatacgagg gaaatgcttg atgaagcagt agcagtttat caaaaaatag
    10021 gaaaagaaat ggaaattatt taactaaatt tagttttttc gtctatttaa aattagagaa
    10081 catgttcacg catatattgt taatcatctg aagatagtag taaaaaagat cagggaggat
    10141 catcatgaaa aaagtattgg tgacaggatg tttaggacaa attggttcag agttgatcac
    10201 acggctacgt caagaactag gcagtgaaaa tgtcattgcg acagatatac gcatgcctga
    10261 agtcattgag aaaaacgata tctttgagat cctagatgta atggattacg aaaaaatgcg
    10321 cagcatagca gaacaatatc aagtggacac attgattcat ttggctgctc ttttgtcagc
    10381 tgttgcagaa gcaaaaccac aattagcctg gaatttgaac gtgactgggc tggtcaatgc
    10441 attggaagtc gctagagaat tccagctgaa attttttacg ccaagttcaa tcggcgcgtt
    10501 tggtccaaat actccaaaag atcatacccc acaagatact cttcagcgtc ctacaaccat
    10561 gtatggggta acgaaggtag ctggagaact actatgtgat tattattatg tgaaatatgg
    10621 cgtagatact cgtggtgtcc gtttccctgg attgatttct tatgcaacct tgccaggagg
    10681 cggtacgaca gactacgcag tcgatattta ttattcagca atcaaagaag gaaagtacac
    10741 tagtttcatt gatcaaggta catcaatgga tatgatgtat atgccagatg cgatcgatgc
    10801 cattataaaa ctcatgaatg cagatcctga tcgattggtt catcgaaatg ccttcaatat
    10861 atcggcgatg tcttttgacc cggaagagat caaagcatct attcaaaaaa tcataccaga
    10921 ttttgaaatg gattatgatg tggatcctgt acgtcagtca atagcagaat cttggccaaa
    10981 ttcactagat gtttcttgtg cgcaagagga atggggcttt tcgccgaaat acgacttaga
    11041 tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa ttggtagaga cggtataaaa
    11101 caagaaccac atccaaaaag ttttttatac ttttgggatt ggctatggta tgaaagggga
    11161 caagggatgg aagaatatca agccacgcca gtaaaagaag taaaaataga aaatgaatta
    11221 aaacgtacga tgggattttt tactgcttta tcgactgtta tgggcacagt gatcggtgca
    11281 ggggtatttt ttaaagccgc aagcgtagca gaagttacag gatccgccag tttgcatatg
    11341 ttttcttggt ttctcggtgg tatgatttct gtctgtgcag gactaacagg agctgaactg
    11401 gcagctgcta ttccagaaac aggagggatg attaaatata tcgaacggat ttacggaaat
    11461 acagcagctt ttttattggg ctgggcgcaa gtcgtgattt attttccagc aaatgtagca
    11521 gccttgtcga tcattttcgg tacacagttc gtcaatctat ttggtctttc ccagtcaatg
    11581 attgttcccg tagctgttac agctgctgta tcgatcctgt tgatcaattt tttaggttct
    11641 aaagctggag gggcttttca gtcgattacg cttgtctgca agcttattcc tttgtttgtg
    11701 atcgtcattt tcggtttgtt ccgacaagaa ggagtagact tccaactgtt tccgatccaa
    11761 gcaggagaaa atctttcatt tttctcagcc ttgggagcgg gcttgctagc aacgatgttc
    11821 gcatacgacg gttggataca cgtaggaaat atttcgggag aattgaaaaa gccggcgaaa
    11881 gatttgccaa aagcaatttc tttaggaatc atcggaatca tgatcgttta tttattagta
    11941 aatgcggtgt tcttaagaac cgcatctatc gacggagtcg caggaaacag caatgcggca
    12001 agtgacgttg caaaaatgat ttttggcggc ttcggtggaa gactggtcac agttggtatc
    12061 ttgatttctg tttatggaac catcaatggc tataccctta ctggaatgcg tctcccttat
    12121 gttatggcaa aagaaaacaa cctgcctttt agcaagctct ttgctaaact tcatgataaa
    12181 actaaagttc ctgtagccgc aggtatctta gagctagtca tcgctattgg catgatgatg
    12241 atcggtggtt ttgatacact aacggatatg ctgatctttg tcatttggat tttttatacg
    12301 atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac ctgatttgtt tcgaccatac
    12361 aaagttccaa tgtatccgtt tattccacta gtagcaatca ttggagggac ttttatcgta
    12421 tcaagcacgc ttatcactca gaccttttta gcttcgatgg ggatagtatt gacacttgct
    12481 ggtatcccga tttatctcta tttaaaacgt agatagctaa aacattcgaa ttttattaga
    12541 actgcacttc tctgccaaac aaaatatttt atttaaatga ggagtacgtg gaagaaatgt
    12601 caaaagtact cgttaatttt gatcacgtaa atgtcgtttt gtctacgatg aaatagcaaa
    12661 gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt actttgattt gcgtaactga
    12721 actattcggc gtacgccgcg ataaatattt aataaaacca agcaaccaga aatgaaaatg
    12781 ggaagccaaa tcagatagac agggtagcca agcactttag acaaagcatg tggagtcatt
    12841 ttatccattt caagaagtgc ttgctgccaa gtctgaagat tgaagactag catgaaaccc
    12901 gaaataatca ggagaataaa tcctaaataa tgaattgtag ttctttttct tacataagcg
    12961 atcgtagcat aaaggaacag taaaaaaata ggtacgccaa aaacaaagta catattcagc
    13021 atctcgacac cccctttgtg tttatcttac tttactttga aagaaatgag aaataatagc
    13081 ctcgttactt gcttgaaaca gcaaaggact gctaagataa gagagataca aagaatcaag
    13141 gaggagtcat atggcaagtt atatcgaacc gattcgtttt gcgctgattg tttttccatt
    13201 tttagcctta gcgatctcat ctgttttttt tatttatgaa tatcgaaagt atggaacatt
    13261 tctagtaaca agggcagtta ttttgtattc tttcgttttt tatttattgt gtgcgtattt
    13321 tttggtgatc ttaccacttc cggcaaagga gacggttgcc caaatgacag ggccaaagat
    13381 ggagctgcat ttatttgctt catggcaaca tttcagagac aacacggtat tggtcttgtc
    13441 tgaacctagt acctacctgc cggcaatgaa gcagagtgta tttttggaac cagcttttaa
    13501 tgttttatta ctcataccat ttggcattta tttaagatat tatttccggc tttcttttat
    13561 gaaaacgatg attgctagtt tctgcctttc tctatttttt gaattgacgc agctaagtgg
    13621 actttatttt atctacccaa gaccataccg cttatttgat gtgaatgatt tagtgacaaa
    13681 tacattgggt ggaatcattg gttttgtcgt tacgccgtta tttacattta tgcttcctac
    13741 aagaagacga atggatgaac tttcttatga aaaaggaaag actgtctcat tgactcgacg
    13801 cttggtcgct tatttgatcg actggacatt tttatctctt attaatttgg tagcggcgat
    13861 tttctttaaa attgcgttcg attcaggggc agttacttct catatctggt ggcttttatt
    13921 agaagtaggg gtatacttta tgattgtacc gtttataacc aatggatgga cacttggcaa
    13981 aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa cgaatttctt taaaagcatt
    14041 gatgatccgc tacgggtatc tgtactttct tttttatggt ttaagctggt tggggcagtt
    14101 gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg cagatgagtg cagtattcat
    14161 ttctctcggt gtcttgttac tacaaggtat ttttatttta aatatcttgc tatcattttt
    14221 gagaaaaaaa cggattctgt tttatgaaaa agctagtcac acatatactg ttagcacgat
    14281 tggccaaaca aaggatgatg attctcgaaa ttagctgagc aaaaacgctt tgtctgtgtt
    14341 ataatgccaa agtcgtgata atttaaagag aagaggtgca cgaatgaata attttgatat
    14401 attccgcttc aaaccgttta tcaatgaagc gttaaccgca aagggcttca aacagcccac
    14461 agaggtccag gaacgtttga ttcctttaat tgcaaaagga aaaaatatca ttgggcaatc
    14521 tcaaactggt acaggaaaaa cacatacgtt tttgttgcct ttgtttgaaa aaatcaatgc
    14581 agaaaaagag gaagtacaag ttgttattac agctccaagt agggaactag ctgcacagat
    14641 ctatgaagca gctacacaaa tcgctaaatt ttctacaccg gagatccgtg tctcgaattt
    14701 tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg catcaccaac agccacaggt
    14761 tgtagtaggc acgcctggta gaatattaga catgatgaat gaacaagcgc tgaagattca
    14821 caccgcattt gcatttgttg tcgatgaagc ggatatgaca ttggatatgg gttttttaaa
    14881 tgaagtagac caaattgcaa gtcgattacc agaaaagctg cagtttttag ttttttctgc
    14941 cactattcca gaaaaacttc gtccattctt acgaaaatac atggaaaatc caatcattga
    15001 agaaatcaaa ccaaaagcag ttatttctga agacattgaa aattggctga tttcaacaaa
    15061 aggtaaagat gagaatcaaa tgatttatca actgctgaca attggtcatc cttatttagc
    15121 aatcgtattt gccaatacaa aacagcatgt ggatgaaatt gccgattact tgaaaaacca
    15181 aggcttgaaa gtagcaaaga ttcatggaga catcacccca agagagagaa aacgagtgat
    15241 gcgacaagta cagaatctgg agtatcaata tgttgtagcg actgatttag ctgctagagg
    15301 gatcgatatc gaaggtgtct ctcatgttat taatgcagaa attccagaag atctagactt
    15361 ctttatccat cgtgtcggac gtactggacg taatggctta aaaggaacgg ccattacgtt
    15421 atattcgcca aatgatgagc aagccattga tgcgatagaa aaattgggcg tctcatttga
    15481 accaaaagaa atcaaaaacg gggaaatcgt caaaacatac gatcgtaata gacgtgccaa
    15541 acgagaaaaa tcaaaagatg tattagatcc cacgctgatt ggtcttgtga agaagaaaaa
    15601 gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg gcaattgcag aaaaaaataa
    15661 aaaagaacgc aaaatcgaac gcagacagca aagccgtact gctcgtaaaa ataagaaaaa
    15721 ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt gtcacaatct cttgttttta
    15781 agctagactt tttttcattc cgatacaaag tacttcatct tcaataaaag gttctgtgca
    15841 agtatgatac ccttgttttt cataaaaatc tacagccgtc atttcagcta ctacataact
    15901 agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct tcaagcaact gaccgcctaa
    15961 cccttttcct cggtattctt ttgctacgca aaatcgttcc ggcttgaagc aagtaggtgt
    16021 tttcttttca taacgcaaag tagctactgg tcttttttga tcaagaaata gataataggt
    16081 ttgttgcggg atatcttttc cgtcgaattc tagttctgca ggaatccctt gttctaatac
    16141 aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc cattcatccg ctccaactat
    16201 ttttttcatc atattcctcc ttgtcatgaa tagcagagat gtattgattc ctttattctt
    16261 atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga aaataaaaat tgagatattg
    16321 acagtgatca atagaatgcg tatactaatt aagtacgaaa aggatatgat ttgtttttta
    16381 agactcacag aaaattcttt cttggctgaa aaaagaatag tcactaatca aattgctccc
    16441 tttttctatt ttggtagaaa taccgacgca gctcagcgtt atcgagttta agaggtaatg
    16501 attacacatc attgcaatca aggtggtacc gcgagttttc gtccttggct gtgatggtgt
    16561 ttttttgtat ttaatttata gaaagcaggt aatgacatga aacaattaag tagtgcacaa
    16621 gttcgacaaa tgtttcttga tttcttccaa tctaaaggac atacgattga acctagtgcg
    16681 tctttgatcc ccgtgaacga tccaacctta ttgtggatca actctggtgt tgcaacattg
    16741 aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa gaatcacaaa tgcccaaaaa
    16801 tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag cacggcacca tacgatgttt
    16861 gagatgctgg gtaatttttc gattggtgac tatttcaaaa atgaagccat ccactgggca
    16921 tgggaatttt tgactgatcc aaaatggatg gcattcgatc cagaaaaact ttatgtaaca
    16981 gtttatccaa aagatacaga agcaaaacgc atctggcatg aagaagttgg cctgccacta
    17041 gatcacatta ttgatgtaga agacaacttc tgggatatcg gtgcaggccc atgtggtccg
    17101 gatacggaaa ttttctatga ccgtggagaa gcttataacg atttagcaga agacgatcct
    17161 gaaaactatc caggaggaga aaatgaacgt tatttagaaa tctggaactt agtattttca
    17221 gaattcaacc ataagcctga taacacattt gaaccacttc ctcataaaaa cattgatacg
    17281 gggatgggat tggaacgcat ggtctcaatc gttcaagatg cgtcaacgaa ctttgagaca
    17341 gacttgttta tgcctattat ccacgccgta gaaaagctaa gcaaacaagt aaaatatggt
    17401 gaaaacccag taacagatat ttcttacaaa gtaatcgcag atcatattcg cgccctttca
    17461 tttgctattg gcgacggtgc attgccatcg aatgaaggga gagggtatgt cttacgccgt
    17521 ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta ttgaacaagc attcttatat
    17581 cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt atcctgaagt acttcaacaa
    17641 aaagaattta ttgaaaaagt tatccgtaca gaagaagaac gtttcaatga aacaatcaat
    17701 gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa aaaacgaaaa cgggacgact
    17761 ctagcaggaa aagacatctt caaactatac gacacatatg gcttcccggt agaattaacg
    17821 gaagaggtgg cagaagatga aggactgaaa gttgatcatg ctggttttga aaaagaaatg
    17881 gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg aaaaatcaat gggggtacaa
    17941 tctgctttat tgacagatat caaagtagaa agtaaattca ttggatacac agaacaagaa
    18001 tcagatagtc aattattggt catcgttaaa ggtgagtctc ttttgaatga agtcgcagaa
    18061 ggtgaagctc aaatgatctt tgatcaaaca cctttctatg cagaaatggg tgggcaagta
    18121 gcggatcaag gatggatcat gaatgaagta ggcgaaatcg tagcagttgt tacagatgtt
    18181 caaaaagcgc ctaatggtca atttatgcac accgtagaag taaaagcacc aatgagtgaa
    18241 ggacaaacct atcatctatt gatcgatcaa tcgatgcgca atcggatcat caaaaaccat
    18301 acagcaaccc atctactgca caaggcattg aaagaagtac ttggcgagca tgcaaatcaa
    18361 gctggttctt tagtcgctcc tggacattta cgattcgact ttacccactt tggtcaaatc
    18421 acttcagatg aattagctga aatggaaaga atcgtcaacg aaaaaatctg ggaagctatc
    18481 ccagttgaaa caattgaaac agatatcgat acagccaaaa acatgggtgc aatggctttg
    18541 tttggtgaaa aatacggaca tgacgttcga gtagtaaata ttggcggctg gtcaatcgaa
    18601 ctgtgcggag gcacacatgt agcaaataca gaaaacatcg gaatcttcaa aatcgtttct
    18661 gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg taacaagtaa agaagcgtac
    18721 gaactacttg aagaagaaga aaaacaacta aaacaagtag caacaattgt taaatcacct
    18781 caattgaaag aagttgtttc aaaagcggaa caattgcaac agcaagtaag agagctacaa
    18841 aaggaaaatg aacaattagc tagcaagtta gcgaatcaac aagctggtga tgtattcaaa
    18901 gatccagaaa cgatcaatgg aaaaacaatc attgcagcac aagtaaaagt gaaagatatg
    18961 aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa atatttcaga tattcttgtt
    19021 ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg caatgacgaa agaatcaaat
    19081 gaagctggac taaaagctgg cgacttgatt aaagcaatcg caccgaaagt aggcggtggc
    19141 ggtggtggac gtccagacat ggcacaagct ggcgggaaaa atcctgctgg tattccagat
    19201 gcacttaaag ctgcgaaaga atgggttgcg caacaatagg gcgtttacgt ttgacagaaa
    19261 aacaaaagtt caaacattga acgaaacatg attatggggg cgaagacaaa caagtcttgc
    19321 cctcatactt ttttcaattg gatggcgcat ctaatcaaat ggtcggattc ggatggtctt
    19381 tagttgacga aagtgacaga aatttttacg attagtataa ataaaaaggg gtgaaaaaat
    19441 gaatagtaga aataagacct ttcgactagt cttacgtgcg atcttgttag caatcatcat
    19501 cgtacaagcg atggttcctt ggctggggtt tattccatta ggattcatta gtttaacaat
    19561 tatccatatc acagtaatta ttgctgcagt agtattaggc ccaaaagatg gcatggtgat
    19621 tggcttgttt tggggaatcg ctacaattgt tcgtgcctat gccatgccaa caacgccatt
    19681 tgatacatta gtgttcacga atccgattat ctcggtagtt cccagagtac ttgttggctt
    19741 agtagcaggc ttggttttcc actggattta tcaaaaaaat aaatcaataa cgatcagctc
    19801 agcctttgca ggggtactgg gttcattggt caatacagtc ttagtgttag gattcatggg
    19861 attattttat acaggtgcaa cggcagatgc ctatggtgta gactctgctc ttttatttaa
    19921 aaccttagca ggggttgcag caatcaatgg gataccagaa gcaataggtg cgggaatcat
    19981 aacaccatta ctagcaaaag cgttatttgc agcaacaccg ttgaaaccag aataatgacc
    20041 atcttttaat agtaatagga cgcacgatag atagaaaaag gaagagagga gaggaaaaca
    20101 atcgtcctct ccatcttttt acctgagcaa caagcaaact agaaggggta aaaaacttgg
    20161 ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca gcggacaaaa aaaggagtac
    20221 tagcgggtat cttaggattg gttacgaatc tgatcttgtt tgtctctaag ctaatgatcg
    20281 ggcttttttc aggaagtgtc tccattatgg ctgatgcagt gaacagtcta tcagatactg
    20341 cttcatccat attgactttg atcggattta aaattgctgc aaagccagca gatcaggaac
    20401 atccttatgg acacgaacgc ttcgaatata tcagtgggtt atttgtttcg atcatcatta
    20461 cttatgtagg atttcaattt ttagagtctt ctgctgaaaa aatcatccat ccagaaaatg
    20521 tctctttaac acccatcgtc ttttttgtcc taatcatttc catctttttg aaatttgcac
    20581 aaggcaaaat gtatcaggtt attgcgcaat ccattgattc tgaaacattg agagctacag
    20641 caacagatag ttataatgat gtctttacta cactggctgt attgctttca gcagcaatcg
    20701 aatgggtaac tggatggcgt attgatggat atataggttt tgctttagca ttatatatcc
    20761 tttatagtgg attgacgatg cttcgaaatt ttgtatacga actattagga agtcgcccaa
    20821 cgccagcaga gattgaagaa atggaagagc atttaaatgc ttgcgatgat atacttggct
    20881 atcatgattt attggtgcat aactatggac ccaataaacg ctttgcatca gtccacatcg
    20941 aagtagatga atcaatgaat ttgaatgtgg ctcataagat tattgatctg atagaaaaag
    21001 actttaaaaa gtctttggat gtggaacttg tctgtcactt ggatccaatg cctgttgata
    21061 acgaaaaata ctataatatc ttgcggcagt taaagcaaat tcttcttgaa acaggtacag
    21121 ggcttaatat tcatgatttt agagtaattc atcaaggaaa aacgctgcaa tttgatgtag
    21181 tggtccctga gaaattccag tttgttgata cagaactaga aagaatctta cgtagtcaaa
    21241 tagaagaaaa aatcggagat taccaattgg aaattacgtt tgatcacaat tatcttttat
    21301 attaaatgag aaactataaa aagactcctt aaagttttta atttaaagag tctttttttc
    21361 ttttaattgt ttatggagag cctgacgtgc aagattatct gctcctttat ttttgttttc
    21421 gggcaaccat tgcaggatca ataaagaaaa ttcggataga agttcttgga ttctttgaag
    21481 gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg accgtagaaa ctagtgtttt
    21541 gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg tttttcttta gaaattctaa
    21601 agtttttaaa aagacttcga actctgcttg atggtttgtc cctatagaaa gcgggataga
    21661 tagctgttct tgtttacctt gatagacaat caagattcca cctccactag gaccagggtt
    21721 gccttttgta gaggcatcaa tgtatacttt taacataaaa agagattctc ctttttgttc
    21781 aaactaatgt tatggtaaga ttatatcatt actgaatcgg tgagaggtta gagaatgaaa
    21841 aaaaatattc gatggcagcc tgaactggca catacgatca tctattggtc attgaccttg
    21901 atcattctgt tttttagtct gattctttct ttagaaaaca caggtcctta ttggaaaagc
    21961 aattttgttt taggtatttt tcttgttttt ctatttctag gtttgcggcg ttcttttatt
    22021 ttaaaatcaa actctgtgat tatacgttat gctgcttttt ggaaagaccg agaaatatct
    22081 gtcggacaga ttcgatcttt gacgccaact aatactgggg tgcaaatgat gttgcaagat
    22141 gagaaagccc catctgtttt catgatgcga aaaaaagatc aagtagtcct ttttgatcat
    22201 tttgaaaaaa acggacccaa atcagaatca attccttatc cttatacgaa aaaaagaaaa
    22261 agctaatttt aaaaatcaga acctaaaaaa acgaattttt acaggaaaag aaaagagtga
    22321 gacgtacggt tcatcccgtt tagcgtctca ctctatttgt ttatctattc atgcatacta
    22381 gtatcggtag tctgaacgtt gcctttcttg acatgggcag cttgtgttcc tcgattccct
    22441 tcgatgatct caaattcgac cacttgattt tcttccaaag ttttgaatcc ctcttcttca
    22501 atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat aactgataaa gccgtatcct
    22561 tttttgttgt caaaccattt tacaattcct gtggtcaaag cactcacgac ctttctaaag
    22621 tctgatcata gccttcatta taaagagtat ttataagtac gtcaaataaa ttaaaaacct
    22681 gtaattttat gttttttttc tgaataaaaa aaggtataat tggcatatct taacaaagaa
    22741 gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa atgaagaatg atctgcaaat
    22801 ttcacaagaa acagagctag aaccgattgt tgaagtggct agtaaattag atcttaagga
    22861 agacgatttg gaactgtatg ggaaatataa ggcgaaaatc aatttttctg gaatcaatcg
    22921 atcaaaggat aacgctgagg ggcatttgat cttagttact tccatcaatc caacaccagc
    22981 tggcgaagga aagtcaacga tcactgtagg gttaggagac gcgctcaata aaatcaataa
    23041 aaaatctgtt attgcattgc gagaaccctc acttggtcct gtgatgggaa tcaaaggtgg
    23101 tgctgcaggc ggaggatatg cacaggtatt gcctatggaa gatatcaact tgcattttac
    23161 tggtgacatg catgctatca caacagctaa taatgcatta tctgctcttt tagataatca
    23221 tattcatcaa ggaaatgaat tgaacatcga tgcccgccga gtgatttgga aacgggtagt
    23281 cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc ttgggtgggc caatccaagg
    23341 tgttccaaga gaagatgggt ttgatatcac agttgccagc gaaatcatgg ctatcttgtg
    23401 tcttgcggca gaccttgaag atttaaaggc tcgtcttgca aggatcgttg tcggctatac
    23461 atttgaccgt cagcctgtga ctgctggaga cttgaaagca gaaggcgctc tggcattact
    23521 gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt tacggaacac cagcttttgt
    23581 ccacggggga ccgtttgcca atatcgctca tggctgcaat agtattttag ctaccaagac
    23641 agcattgaga ttagcagatt acgttgtcac agaggcagga tttggtgcag atcttggcgg
    23701 agagaaattt ttagatatca aagtacctaa cttgaaaaaa gcgccggatg ctgtggtgat
    23761 tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg aaaaaagatg aacttaaaaa
    23821 tgagaatctt gatgctttga aagtaggttt tgcaaattta aagcgccata tacgtaatat
    23881 ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa ttcgtaacag atacagacaa
    23941 tgaactcaca ctgttggagc acttgtgtga aaatcagggg attcttgcca agagagcgag
    24001 tgtatgggca gatggagcag aaggcggcgt tgatttagca aaagctgtag tacgattgat
    24061 tgatagaaaa gaagctaatt acaagccatt ataccgccta gaagaaacga tacaagaaaa
    24121 gacagaaaca atcgtcaaga aaatttacgg aggaaatggt gttgttttca gcaaaaaagc
    24181 gcaaaaacaa atagaagagt ttacgaagaa tggatgggac aaactgccga tttgtatggc
    24241 aaaaacacag tattcatttt ctgatgatcc ttcactgcta ggtgcaccgg aagatttcac
    24301 catcacgatc cgcgaaatca tcccaaaatt aggggcagga tttttagtag ccttgactgg
    24361 agatgttatg acgatgcctg gtttgcctaa aaaacctgct gcattgaata tggacgtgac
    24421 aaatgacgga gaagtgttgg gattgtttta agcttgatta taatctacca tcgaaggagc
    24481 tgtattttga ctacagcttc tttttttaga cgatagggaa ttaattttgt ttacactagg
    24541 atcattcttt ttctttattg tattttgagc tatactaaag cataatagga gggtatgatg
    24601 aaaacgacat ttataagaaa aaccggtttt tacggtatgg gtagctcgat tcagctaaga
    24661 atcaacaatg aaaaacgcag tgttctcagt catgaacaaa agataacgct tgatctggaa
    24721 gtgcccttta cgatgcaggt caccttttat tggctaaaaa gccccgttta tacagtgaaa
    24781 gaagcaaagc ctgcttatgt gatcacaatg aattacttga ttcttcaaat ctatccgttt
    24841 ttatttctag caactgggtt gggggccgtt ttcctacaaa atttattttt cagttttttt
    24901 gcagttattg tgttgattgc gttctttttc tatataaaaa accgggcata tttgatcaag
    24961 gaggaaaatt atggcaaact ctgatctttt tttaatcagt ttcaatcgaa tcgaaaaatg
    25021 gatgagagac gagatgggaa atgcacgaaa tatgggattt accgaacttg tcagacgcct
    25081 agctcaaaga aaacaattaa tgatcagaaa atacgaagat gatcttttac agcttgctca
    25141 gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat tttgtcattg cagagccaaa
    25201 tgattggaca gtcaagcgaa tccagctgat cgaacaagaa ctgattcagc ctgaaaccgt
    25261 gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa gatcttccgt tacttgaact
    25321 gttaaagata gtagcagaaa aaaggtattc acaatttccg ttatacaata aaggaaaatt
    25381 tgtagcattg attactttac gtaatatcgg gttttggcta gcaaaagaaa gccaaaaagg
    25441 tccggttgat ttaacaaata aacgagcgtt ggatttgatc atccaaaacg gaaagtacac
    25501 aaattatcat tttgttccag ctaaaacaca tatttacgag gttgaagcga tgtttcgtga
    25561 gcaagggact ttggaagccg tacttatcac taaagatggg aatcccgatg gtaatctgct
    25621 cgggatcgta cgacctcgtg atatttataa acaaatagaa aaggattgat tttttgttaa
    25681 ttatttattg gatattcagc gctttgctag taggagtgga tcagttggtc aaatggtgga
    25741 tcactgataa tctagcgctt ggagagacga aaaatcttat accaggtatt ttgtcactga
    25801 atcatattcg aaacactgga gccgcatgga gtatgctaga agggaagatg tggttcttta
    25861 ctatagtgac actcattgca gtcgttgtga ttctcacatt gatgattaaa aatcgtgaaa
    25921 aaggtaatcg ctggttcatg attggattga gtttgattct agctggtgcg attggcaatt
    25981 ttatcgaccg tattcgtctt ggctatgtag tagatatgtt ccagacagat tttatgagct
    26041 ttccgatttt taacgtagca gatgtgacac ttgtatgtgg agtgatttgt atgttaattt
    26101 atattatttt agatgaaaag gatcaaagaa aaaaatgaca gaacttaaaa cgacgattca
    26161 ccatgaatct ggtaggatcg ataaagtatt gactaattta ttcaccgatt acagtcgttc
    26221 gcaaattcag ctgtggctga aaaatggagc ggtttctgtc aatggacagc cagtcaaagc
    26281 aaattacaaa gtaaaacaag gagacgagat tactgtcttg atccccgaac cagaaacatt
    26341 agatgtggtc ccagaaaata tcccgttgac gatcgtttac gaagatgaag atgtagcggt
    26401 gataaacaaa cctcaaggaa tggtcgttca tccttcagca ggtcatacgc atggcacaat
    26461 ggtcaatgcg ctgatgtacc atatcaagga tctttctacg atcaacggcg ttattcgtcc
    26521 aggtattgtt caccgaatcg acaaagatac ttccggactg ctaatggttg ccaaaaatga
    26581 ccaggcacac gaatcattag ctcagcaatt aaaagataag acctctttgc gcaaatatgt
    26641 tgctttagtc catggagaga ttcctcacga aaaaggaacc atcaatgcgc caatcggccg
    26701 ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat gggaagtcgg ctgtcacaca
    26761 ttttactgta ttggaacgtt tcgaaggatt tactctggtt gaattaaaac tagaaaccgg
    26821 aagaacacac cagatccgtg tgcatatgaa gtatatcggt tatccgttag ctggagatcc
    26881 agtatacgga ccgaagaaaa ctttgaaagg caatggtcag tttctccatg cgcaaatgtt
    26941 aggttttacg cacccgacta caaacgaaaa gatgatcttt gaagcacctc ttccagaagt
    27001 ttttgaaaaa actttagaaa aattaagaaa aaacattgca ttttaattta gataacggta
    27061 tagtaattaa caacgaaagc ataaaactta atagaattcc tttaagttta gtcccgtgag
    27121 gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat aagtagattg ctcattgaca
    27181 tagtatagct atcagtgtat cagtatacgc tcagtctaaa cattcctcct gtcctcttag
    27241 ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa atgcaagcaa aagaagtagt
    27301 agatcaggta accatgaagc gagcattgac tcgaattact tatgagatta tcgagagaaa
    27361 ccatagtatc caagatatcg tattggtagg tatcaaaaca cgaggaatct acattgcatc
    27421 aagaattgcc gaacgcctga agcagctaga agatatcgat attcctgtag gagaactgga
    27481 tatcacttta taccgagatg acaaaaaaga aaatccagaa gaaccggaac ttcattcttc
    27541 tgacatccca gtttccttag aaggaaaaga agttattttg attgatgatg ttttgtatac
    27601 aggacgaacg attcgagcag caatggacgc agtaatggat tttggcagac caagaaaaat
    27661 ttcattagca gtcctggtcg atcgtgggca tcgagaattg ccaatccgtg cagattatgt
    27721 tgggaagaac attccaacat ctcgggcgga agagatttta gtagagatgc aagagcttga
    27781 tggacaagat cgcatcatga ttttgaaaga ggaagattag aggagagaga aacatgtcgg
    27841 agaaaaaagg atttcataat gatgacgtgg tgttagatat ccacgatcgc ccaaccccag
    27901 gacattgggt aggattaagt ttacaacact tgttcacgat gttcggagca accgtgttag
    27961 tccccatctt agtaggtatc gatccaggta ttgcgctagt cagttcagga ctaggtacat
    28021 tggtgtactt atttactact aaaggaaaga tacctgcgta cttaggaagc agcttcgctt
    28081 tcattgcagc gatgcagctt ttgatgaaaa cagatggtta tccagcgatt gcacaaggag
    28141 cagtcacaac tggattagtc tatttgattg ttgcgctgat catcaaaaag atcggttcag
    28201 catggctgga taaaatcttg cctccaatcg tcgtcggtcc agtcatcatg gttatcgggt
    28261 tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa tcagggcacg tatgatttca
    28321 agtatattgc tgtagcgctg atcacattag gattaacaat tttcttcaac atgtggctaa
    28381 gaggttttct cggattgatt ccgattttac taggtattat tagcggatac atcgtagcct
    28441 tgctgtttgg aatcgtggat actaagccaa tcgtagacgc tgcctggttt gctgttccta
    28501 actttgagat tccctttgta caatatgaac caaagctata tcttggagca atcacaacaa
    28561 tggcacccat cgcttttgtg acgatgacag agcatatcgg ccatcttatg gtattgaata
    28621 aactaactaa acgtaatttc tttgaagaac cgggtcttca taagacgttg acaggtgatg
    28681 gattagcaca aatcgtggca gcctttgtcg gaggtcctcc tgtaacaagt tacggtgaaa
    28741 acattggtgt tctggctatc acacgtgtcc atagcgtgtt tgtgatcggt ggagctgcag
    28801 tatttgcagt cattttagga ttcgtaggaa aattaagcgc tttgatttta agtatccctg
    28861 gaccagtcat ctcaggaatc agttttatct tatttggagt aattgccgca agtggaatga
    28921 agattttaat cgagaacaaa atcgattttg ataaaaagaa aaatctgttg attgcttcag
    28981 ttatcttagt agtaggaatt ggcggactcg tctttgaagt aggcacattt acattgtcgg
    29041 caatggcatt agcaactgta cttggcatca ttttaaatct tatcttacca gaaacttcac
    29101 gaagcgaaga aaactaagga ggaaacatta tgatcatcaa atcagaacgt atcagcttaa
    29161 agcatttatt gaccgttgag gcacttactg atcaagaagt tatgggcttg atccgcagag
    29221 ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa gcgccagtac tttgctacaa
    29281 acctcttttt cgaaaatagt actcgcacac ataaaagctt cgatgtagcg gagaaaaaac
    29341 tagggctaga agtgattgaa tttgaagcaa gcacaagctc tgtccaaaaa ggggaaacac
    29401 tatacgatac agtactgacg atgtcagcat taggcgtaga cgtagcggtt atccgtcatg
    29461 gtgatgagaa ctattatgac gaactgatac aaagtaaaac aatccagtgt tcgattatca
    29521 atggaggaga cggaagcgga cagcatccaa cccaatgctt gcttgatttg atgaccattt
    29581 atgaagaatt tggtcatttt gaaggtctga aagttgccat cgtaggtgat atcactcact
    29641 ctcgcgtagc taaatccaat atgcagatgt taaaacgtct aggcgcacaa gtattcttct
    29701 caggtcctag agaatggtac gacgatgaat tcgaagtgta cggacattat atgccattgg
    29761 atgaactact agatcaagtt gatgtcatga tgatgcttcg ggtgcaacac gaacgccatg
    29821 atggaaaaga aagtttctca aaagaaggct accatcagga acatgggtta acagttgagc
    29881 gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc agcaccagtt aaccgtgatg
    29941 tagaattagc tgattcatta gtggaaggat tacagtcgcg gatcgttcag caaatgagca
    30001 atggagtatt cgtcagaatg gcaatcttag aagcagtgct aaatggaaaa gcgtaattat
    30061 aggaggatga aaaaatgaaa acactcatta aaaacggtca gatcaataca cgaaaaaata
    30121 tgacgacacc agcagaaatt tggatagaag atgggcgaat caaagcaatc ggtacaggat
    30181 tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg acaattgatc acacctggtt
    30241 tagtggacgt ccatgttcat ttgagagagc caggatttac atacaaggag acgatcgaag
    30301 ctgggactcg ctcagctgct cgtggcggtt tcactactgt atgcgcgatg ccgaatttaa
    30361 atcctgtacc tgatacggca gaaaagctga gacaagtata tgacatcatt agaaaagatg
    30421 cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa tctgcgaagt gagaaattag
    30481 ttgatcaaga agcactgatt gaagaaggtg cttttgcttt cacaaatgac ggtgtaggtg
    30541 tccaaacagc tgggacgatg tatctggcta tgaaagaagc tgcaaaaaac aataaagccc
    30601 tagtagccca tacagaagat gaatctttat tatttggcgg cgttatgcac gctggcaaga
    30661 aggcagaaga acttggtctt cccgggatct taagcgtaac cgagtcttct caaattgcta
    30721 gagatctgtt gctagctgaa gcaactggtg ttcattacca tgtttgccat gtttctacta
    30781 aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg aatccacgta acagcagaag
    30841 tttcacccca tcatcttatt ttgatcgacg aagatattcc cgaagatttc ggcttttgga
    30901 aaatgaaccc gccgctaaga ggacgggagg acagagaagc tttgatcgaa ggcttgcttg
    30961 acggtacgat cgattgcatc gctacagacc atgcccccca tggattagaa gaaaaaagcc
    31021 aaagtttcat gaaatcacca tttggtatcg taggaagcga aacagcgttt caactgatct
    31081 atactcattt tgtagaaact ggtcgattca cgttggaaca agtgatcaat tggttggcag
    31141 ttaaaccggc tgagattttt ggtttgaatg caggaacgct aacggttggt gcccccgctg
    31201 atgtagcagt ttttgatatt acacaaactt gcacgatcga taaagaagac tttttatcaa
    31261 aaggggagaa tacacctttt atcggctgga aagtaaaagg cgaaacacaa atgacttttg
    31321 tcaacggaaa acttgtgtgg cagaagggag aataaaagta tggaacgttt gcttatatta
    31381 gaagatggaa cagttttcga aggaaaggct tttggtgcag atgctagtgt cttcggagaa
    31441 atcgttttta caacaagtat gactggttat caagaaacta tcactgatca aagttttaac
    31501 ggtcaaatca ttacatttac ctatcctatg gtgggtaatt atggggtaaa tagagatgat
    31561 tatgaatcga tttctccaac atgcaaagga gtagtagtaa aagaacatgc acgtgtagct
    31621 tcaaactggc gaaaccaaat gacgctagat tcatttttga aacaaaaagg aattcctgga
    31681 atatcaggta tcgatacgcg cgcccttact cgcaaaatcc gtgaagtcgg aacgatgaaa
    31741 gctagtatag ttgatgctgg agattccttc gaacatgcat ttgatcagct gaaagcaacc
    31801 gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca aaccttatcc aagtccagga
    31861 acaggtcgga aagtcattgt cattgacttc ggcttgaaac atagtatttt acgagaattg
    31921 agtaaaagaa actgtaacct cacagtactt ccctataaca cagatgccga gacgatttta
    31981 gcgctatcac cagacggagt catgctgacg aatggacctg gtgatccaaa agatgtgcca
    32041 gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac cgatttttgg tatttgtctc
    32101 ggtcaccagt tatttgcttt agccaacggt gcagatacct ataaaatgaa attcggacat
    32161 cgaggattaa atcacccggt acgagaagta gcgaccggaa gaattgattt tacttctcaa
    32221 aatcatggct atgcagtcga tgaagccacg attgatccag aaaaactcat cgtaactcat
    32281 gtagaagtaa atgacggaac agtagaagga gtcaaacaca gagattatcc cgctttcagt
    32341 gtgcagtttc atccagatgc tgcccctggt ccgcatgatg cactacattt atttgatgaa
    32401 tttatggaaa tgatggacgc aggaaaggag cagtaaacag atgccgaaac gtacagatat
    32461 caagaaaatt atggtgattg gatctggtcc gatcatcatt ggtcaagccg cagaatttga
    32521 ctacgcagga acacaagcct gccttgcctt aaaagaagaa ggatatgaag tggttttagt
    32581 aaattctaat cctgcgacga tcatgacgga taaagaagtg gcagatcaag tatatatcga
    32641 accgatcaca cttgaatttg tatcaaggat tcttcgaaaa gagcgtccag atgctctcct
    32701 tccaacttta ggcggacaga caggcctcaa tatggcaatg gagctggcag catcaggtat
    32761 tttagaagaa ttgaacatag aacttctagg aacaaagctt tctgcgatcg atcaagcaga
    32821 agatcgtgat ctattcaaac agttgatgaa agaattgaat cagccaatcc ccgagtctga
    32881 aatcgtcaat acagtagaag aagctgtaga ttttgcaaat aaaatcggct atcctgtcat
    32941 cgttcgtcca gcctttactt taggcggaac tggtggaggt atgtgtgaaa atgaagaaga
    33001 attacgtatc gtatcagaaa atggattaag tctttccccc gctacccaat gtttgattga
    33061 acgaagtatt gcaggtttta aagaaattga atatgaagtg atgagagatt cggctgataa
    33121 tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg ggtatccata caggtgattc
    33181 tatcgtattt gcccctagtc aaacattgtc tgaccatgaa tatcaaatgc ttcgtgatgc
    33241 ttctctttcg attattcgag cacttaagat cgagggaggc tgtaatgtcc aactcgctct
    33301 tgatccacat agttttaatt attatgtgat tgaagtcaat ccgcgtgttt ctcgttcatc
    33361 tgcgttagca agtaaggcga ctggctatcc gatcgctaag ctagctgcta aaatagcgct
    33421 tggattaaca ttagacgaaa tgaaaaatcc tgttacagga acgacttttg cagaatttga
    33481 acctgcatta gattatgttg tagctaaaat tcctcgctgg ccgtttgata agtttgaaaa
    33541 cggagaacgg cttttaggca cgcagatgaa agcaactggt gaagtgatgg ctatcggtcg
    33601 gaatatcgaa gagtctttat tgaaagctgt gcgttcttta gaaatcggta cacaccatat
    33661 cgaacttcct gagttggcag acatcacgga cgatgaccta atccaaaaag tggttcgagc
    33721 acaagatgat cgcctgtttt atgtagctga agctattaga agagggtaca ccatagaaga
    33781 attagcggat ttgacaaaaa tcgatttatt ctttttagat aaactgttgc atatcgtaga
    33841 aatcgaacag cagttgaaac agcagccgtt ggatgacaag atattgaaaa cagcgaaaca
    33901 aaacggtttt acagacaaaa aagtggcgga gctgtgggaa ataaacgaag aagccgttcg
    33961 ccagatgaga aaagaaaatg atttgattcc tgtatataag atggttgaca cttgtgcagc
    34021 ggaattcgaa tcaaaaacac cttattttta tagttcctat gaatatgaaa atgaaagttc
    34081 acgatcagaa aagccctcaa ttctagtact gggatctggt cctatccgta tcggacaagg
    34141 ggttgaattt gactatgcga ctgtgcattc tgtcaaagca atccagcagg caggatacga
    34201 agcaatcatc atgaacagca atcctgaaac agtttcgact gacttttcta tttcggataa
    34261 attatatttt gagccattga ccttcgaaga tgtgatgaat gtgatcgagc tagaacagcc
    34321 gataggagta atcgttcaat ttggtggtca gacagcaatc aacttagccg aacctttgac
    34381 tgctgctggt gtaaaaatct tagggacaac gatcgaagac ttggatcgtg cggaaaatcg
    34441 tgatttattc gagcaagcgc tgaaagagtt ggatattcct caacctttag gggatactgc
    34501 tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt ggttatccag ttcttgttcg
    34561 tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt gaaaaccagc gagatttaga
    34621 agattacatg gaacatgctg tgaaagcatc tccagaacat ccagtactag tggaccgtta
    34681 cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac ggtgaaacag tactcatccc
    34741 agggatcatg gagcatattg agcgtgctgg tgtccattca ggggattcaa tggctgtgta
    34801 tccacctcaa acattatctg aatcgatcaa gaaaacgatc gaagattaca cgatccgctt
    34861 agcattaggt ttgaattgtg tcgggatgat gaatatccag tttgtcatcc atgaaaatga
    34921 ggtttatgtg atcgaagtca atcctcgagc aagtcggact gttccattct taagtaaggt
    34981 gacaggaatt ccaatggcac aaattgcgac gaaagctatt ttgggagaga aactaaagac
    35041 acttggttat gaaaacggac tttatccaga aacaaaagaa gttcatgtta aagcacctgt
    35101 cttttctttt acgaaattgc agaaagttga tacttactta gggcctgaaa tgaaatcgac
    35161 tggagaagta atgggatctg acagacaatt agacaaagct ttgtacaagg cattcgaagc
    35221 ttctggatta cacttgcctg aatatggagc cgtattattt acgattgcgg acgaaacaaa
    35281 agaagaagca ctagaattag ctaaacgttt tacagaaatt ggctatagtc tgataggaac
    35341 gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc gttgaaacag tagcgaaaat
    35401 ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata agagatggta aaacacaagt
    35461 ggttgtcaat acgattgata aagatcgggg aaatgcttct aaagacggtt tcatcatccg
    35521 aagagaagca gttgaacatg gtattccatt gtttacttct ttagacacag cagatgcgat
    35581 cgttcgagtg atggaatccc gtgctttttc aactaaccct atttaacggc gagcacatgt
    35641 taagacaaaa agacgaaaaa ccgttgcagg aggggacaga tgaaacaaga aatgatggaa
    35701 atcgttcagc aaaaacagct ggcaccaaag atttttgaaa tgacattgaa aggtgatcta
    35761 gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc tcgtgccgcg tgcagacttg
    35821 ctattacgcc gaccgattag cttgaatcat atcgaccacg aaacaaatac ttgccgtatc
    35881 atttatcggg tggaaggtga ggggactaga gtcttctcta ctctttctgc cggagaccat
    35941 ttagatgtca tgggtccttt aggcaatggt tttgatttgt ccaatcttca tacaggagac
    36001 gaagtattta taatcggtgg aggaatcggt gtccctcctc tatatgagtt atcaaaacag
    36061 ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt ttgccacaca tgaagtcgtt
    36121 tattatgaaa aagaatttaa tcgtctagga gaaacaagaa tcgctactga cgatggaaca
    36181 tacggtatgc acggaaatgt cggtaattta ttgttaggaa cgaagacgga acctacagct
    36241 gtttttgcat gtggttcaaa cgggttattg aagacagtgg aacagctgtt ttcttcgcat
    36301 caaaatgtcc agttatcatt agaatcccgc atggcatgtg ggataggggc ttgctatgct
    36361 tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa gtgtgaaagt ttgtgacgaa
    36421 ggaccgattt ttaaaatagg agaggtaatt atatgaatga gaatccttta gcggtcaaac
    36481 ttcctggcct agaattaaaa aatcctatca tgccggcaag cggctgtttc ggttttggca
    36541 aagaatacgg aaaatactat gatttgaatc agcttggatc gatcatggtc aaggcaacga
    36601 ctccaaatgc ccgctttggc aatcccacgc caagagtggc ggaaacacca tctggcatgt
    36661 tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt tatgcataaa cttcttccag
    36721 aattagagga gtacaatgag ttacccatca tcgcaaatgt tgctggtgct tgtgaagaag
    36781 actatgtaga agtttgtagc aaaattggcg aagcaccaaa tgtgaaagca atcgagctga
    36841 acatttcttg cccaaatgtc aaacatggcg gaattgcttt tggaacagat tctgatgttg
    36901 cttttcaatt aacacaagca gtaaagaaag tttcttctgt tcctgtctat gtcaaattgt
    36961 ccccaaatgt aacagacatc gttccaatcg ctcaggcaat cgaagctgga ggggcagatg
    37021 ggtttacgat gatcaatact cttcttggta tgcggattga ccttaagaca agaaaaccga
    37081 ttttagccaa tcaaacaggt ggactctccg gaccagcaat caagcctgtc gctattcgtt
    37141 tgattcacca agtagcaagt atatccagcc ttccaatcat tgggatgggc ggcgtgcaga
    37201 cagtggatga tgttcttgag atgtttatgg ctggagcaag tgctgtagct atagggaccg
    37261 cgaatttcac cgatccgtat atctgtccta aactaattaa agagctccct gtgcgaatga
    37321 gcgaactagg catcgaatcg ctggaaagat taatcaaaga agtgagagag gaacgtgaac
    37381 gatgaatcaa ctagaccaac gaccaattat tgcattagat ttttcaacta ggcaagaggt
    37441 agaagacttt cttcgatttt tcccgaaaga agaaaaattg tttgtgaaaa tcggaatgga
    37501 attgttctac caagaaggac ctgaaatcgt acgttatcta aaagaggctg gtcataatgt
    37561 atttttagat ctgaaacttc acgatattcc gaatacggtc gaaaaagcaa tgcggggatt
    37621 ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct ggcggtattc gtatgatgga
    37681 ggcggcaatg cgaggattag aagaggggac tccagaaggt ggaaaacgtc cgctacttct
    37741 agctatcact cagcttactt ctacaagtga agaagaaatg catgccgatc aactaatcga
    37801 agtttcttta gaaaaaagtg tgatccatta tgctagctgt gccaaaaaag caggattaga
    37861 tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa gaaatggcag gagacgaatt
    37921 tgtttgctta actccgggta taagaccaga aggaacagtc gcaggagatc agacaagagt
    37981 agtcacacct tctcaggcaa aaaagatcgg ctcaactttt atcgttatag gtcgaccaat
    38041 cactcagtca actaatcctt ataaagcata tcaaacgatt caaacagaat ggagctaacc
    38101 taaaatgaat gttgaacaaa gtatcgcaaa agacttatta gaaattgaag cagtattttt
    38161 aaatccaagt aatcctttta catgggcaag tggaatcaaa agcccaattt actgtgataa
    38221 ccgaatcacg atgagctatc caaaagtccg aaaagagatc gcaaaaggat tagcaagcaa
    38281 aatcaaagaa gcttaccctg aagtacaagt gattgctgga actgcaacag caggaatccc
    38341 tcatgccgca tgggtagcgg aaatactgga tttgccaatg gtctatattc gaagtaaggc
    38401 gaaagatcat gggaaaggta accaaatcga aggacgtata tttgaaggtc agaagatggt
    38461 tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg gaagcagctg aagcagcaaa
    38521 aagagaaggt gcggatatcc ttggtgttgc ggctatcttt acgtatgagt tgccaaaagg
    38581 aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg ttgaccaatt attctgtatt
    38641 gattgaagca gctttagaag atcgttatat cgatgagcaa gaattaactc tgctaaaaga
    38701 atggaaaaaa gatcctgaaa attggcagat tgaagcgcgc ttgatgaaga tagagaaatc
    38761 cgatttgtgt ctccagaatc atcaattgga atagcaaaaa tccaaaaact gattgcgaga
    38821 agcatctttt catcaggtat gaaaagaaac ttctatcgtg atcagttttt gattttttta
    38881 aaattcattt ttctaagact ggttagcaga aagaagagaa taatctcttc tcttttttct
    38941 attatatata gattttctct attttttggt aagggagctg tttcaaaaat ggtaaagagc
    39001 ggaaatgttg cgaatatcag ttatttaatg atatgatatt cggaaaaaga aatctcaaag
    39061 ggaggtaact tttatggggt tgaatgaatt tattttagga ttgaacaatt tagagacgat
    39121 cacaagggca cctggatttt ttaaatatac agagcataca gttgcagcac attcgtatcg
    39181 tgtagcatct attgcgcaag ttctaggaga cattgaagaa gcgaatggac aaccgatcga
    39241 ttggaaactg ctctatgaaa aatcattgaa tcatgactac acagagcgtt ttattggtga
    39301 tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga gggatgctgc aaacagttga
    39361 agaaaagatg acggacgaat tcatcaacca agagattcca gctgagttcc aagaagttta
    39421 tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa ggagaactat tagccatttc
    39481 agataaggtt gaccttcttt atgaatcttt tgatgaaatc atcaaaaata acccggaaaa
    39541 agtttataag gagatgttca ttgaggcagt gactacgatt aaaagctttg aacatcggcc
    39601 ttctgttcag tatttcttta aagagatatt tccggaacta ttgaaccagg aattttatgg
    39661 aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag aaagaagaaa aataaaaatg
    39721 atatgagatg cagggggaag tatagttgaa aaagaatatg gatgtcgaat ggggctattc
    39781 tggagacaaa ggtccggaaa attgggcgag tttatgtgat tggtttgcga gaggtgcgga
    39841 atttccattg cagtcgccta ttcatttgac caagggggaa gaaaccaaaa tagaaggaga
    39901 cacgctttcc tttcattatc aaaagcaacg gtttactgac aaggaattca aaaacacgat
    39961 tcatttagta ccttttgacc aactcagtta tgtagagttc aagaaagaac gctattattt
    40021 gacagatatt catttccact tgccttctga acatatcatc aacggaaaac aggaagatat
    40081 tgaatttcat tttgttcata tgaacagcaa aaaagagaat ctagttgtgg gtgtcatgta
    40141 ccagctaatg gtacaggaag gttggctgta taatcaagaa aatggggaaa gttggaactt
    40201 agaaaaacat gagcattggg taaatccgga tgtgttcttt ccggagcaaa aaagccattt
    40261 ccattatatt ggctcattga caactccgcc taccagcggg ccaatccaat ggtttgtaat
    40321 ggatcatgta ggaaaactga accaagagtt tcttctcccc ttcgatggtc agtatgctcg
    40381 accgaacaac cgaccaatcc agcccttgaa tggaagagaa atttattatt tcgaggagtt
    40441 tgagcaatga atattcagca gatgaaatac gtggtcgctg tagcaaacaa tggtagtttc
    40501 agagaagcgg caaagaaaat gtttgtctcc cagccaagtc tttcagctgg tatcaaagaa
    40561 ttagaaaccg agttagggat cacgctgttt actcgaacga atcgaggggc atatttaaca
    40621 gaagaagggc aagacttctt aaatcgtgcc gagaaaatat tggtccagct tgatacatta
    40681 gaaactcact atctaacgag tgaaaagaga gacaattttt cgatcgctgc ccagcattat
    40741 gatttcttag gtcctttgac cgcacagcta ctcgaggaat tcaaagacga gatcaaacaa
    40801 tttcggatca tggagacgac aacagcgaga gtgatcgaag aagtcaaaga gcagcacagt
    40861 gagatcggca ttatttatat gaatgagcat aatcaagctg gtatcagaag atatttacaa
    40921 caaggagagc taagtggccg cagcattgga aaattcaaaa cgcatatttt tttaaggcaa
    40981 ggacatccat tagctgaaca cgcagagatc accaaagaag aattgttatc ttatcctcaa
    41041 gttcgtttta cacaggatgg aaataatttc ccgtattttt atgaagacct tatcgagatc
    41101 cctgatcaag aaacagtgat ttatacgagt gatcgaggta ctttgatgaa tatcgttctt
    41161 gaaactgatg cttacgcttc aggatctggt attgtgattg gagggattcg cgagcacttg
    41221 cggttaatcc ctttggcaga aggcgaacta aatgaatttt atatcattta ttcggcgaaa
    41281 cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc ttactcggtt actggaccag
    41341 cagagctaag aaaagcagat gagaacgctg tttattgaac accgttgatc aaaaaagagg
    41401 ggttgtgaca gaattttgtc acaactcctc tttttgtagc aaacaattta taactaattg
    41461 ctgttgtggg aaagtacgca aatatgattc tagaaacact cattgattac ctgttttgtt
    41521 tcatagctgt aattttttct tcttctggtg tcacgataat cgtcttttgg ttttcataaa
    41581 taacataacc aggcttggcg ccatttggtt ttcggatatg ctttacctgt acaagatcaa
    41641 ccggcacttg ggcagagtat cggtattttg aaaaataggc agctaactcg gcagcttctg
    41701 taattgtttc atctgagggc ttgtcacttt taatgatgac gtgcgaaccg ggtatatttt
    41761 ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat tgtcagctgg tcattttgaa
    41821 gattgttttt accaacaaga atgagcgttc cgtcagaaga aaagtattga tcaggctgag
    41881 atggtttctt acgtttttgt ttttttaagt tcttcttttt caggtatcct tctgaagtca
    41941 attcttcttt aattgcttcg atatccattg ggccggcaat ttccagttga gataagacag
    42001 attcaagata ttggatttca tctttggctt cttggatttg ttcgccaatc agcttaacag
    42061 cgttcttcag cttttggtat cgatggaaat atttctgtgc attttgattt ggtgtcaatg
    42121 ccggatctag tgctattttg attggccgat cttcttcata ataattaggt aaaacaactt
    42181 cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag tagttcgcca tttctacggt
    42241 aattctcagc gttttcggat tctttgagtg tttgttcacg ttttttcaat ttatttttat
    42301 ttcgttttag ttcattttcg atttttcgaa tcagttctcc gccttgttgt tttgcccgat
    42361 ctttctctgc tttttcgtga taatagctat ctaataattg actgagtgtt ggataagctg
    42421 ttacagcaga tgcctgttcg gacaatacct gataagcaat cggtgtgaaa aaatctttat
    42481 tttccgtttc gtaaaaagta ggaataggct gatggctgat ggctgagaaa aattcgtccc
    42541 atacaaccat cttttcatta ggacgttcca gtaatctttt ggtcagctct tgagcgatat
    42601 cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg atctagttca gtttgggaaa
    42661 gccgctgaaa gattttttct ttctcggagc taaatgggtt caagacctct tgttttggcg
    42721 gagcaacata ttctacacca ggaagcaaag aacgataagt gttttgagag cttccaatgt
    42781 gtttgatcgc atccagtatt tttccagttt ctcgattaac taagacgatc gtactatgac
    42841 gtcccattaa ttcaacgatc aatatgatat tttgtagatc acccaactcg tttcgtttag
    42901 caaagtggaa atggatcact cgatcatttt cgatttgttc gatgtcttct aaaatagcgc
    42961 catccaaata ttttcgaagc atcatcacga agttaggcgg attatcagga ttctgataat
    43021 cgatttgggt aatctgtaca cgagcataac ttgggtgcgc agataataat aatcgatggt
    43081 ttttgccgcg tgaacgaatc accagcacga tttcattttc ataaggctga tggattttcg
    43141 agatccggcc agatagtaac gtttcacgca attcgttgac catcgcgtgg gtaaatacac
    43201 catcaaagga catggttcat tcctcatttc ttttcataag tatattcatt ataacgaaaa
    43261 aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag tctagaaaaa tcttggacta
    43321 attacataaa aaacagtgtt tctatcgttg aaatccaaat ttttaggta
//
LOCUS       DARBDN010000015        40937 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000015 DARBDN010000000
VERSION     DARBDN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.015"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(223..1005)
                     /locus_tag="SCH06_000833"
     CDS             complement(223..1005)
                     /locus_tag="SCH06_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077431.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1070..1906)
                     /locus_tag="SCH06_000834"
     CDS             complement(1070..1906)
                     /locus_tag="SCH06_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1077432.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(1924..3333)
                     /locus_tag="SCH06_000835"
     CDS             complement(1924..3333)
                     /locus_tag="SCH06_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1077433.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3347..5170)
                     /locus_tag="SCH06_000836"
     CDS             complement(3347..5170)
                     /locus_tag="SCH06_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1077434.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6013..6339)
                     /locus_tag="SCH06_000837"
     CDS             complement(6013..6339)
                     /locus_tag="SCH06_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077435.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6385..6747)
                     /locus_tag="SCH06_000838"
     CDS             complement(6385..6747)
                     /locus_tag="SCH06_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEG1077436.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6784..6999)
                     /locus_tag="SCH06_000839"
     CDS             complement(6784..6999)
                     /locus_tag="SCH06_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077437.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            7126..7461
                     /locus_tag="SCH06_000840"
     CDS             7126..7461
                     /locus_tag="SCH06_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077438.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7537..9534)
                     /locus_tag="SCH06_000841"
     CDS             complement(7537..9534)
                     /locus_tag="SCH06_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077439.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9632..9907)
                     /locus_tag="SCH06_000842"
     CDS             complement(9632..9907)
                     /locus_tag="SCH06_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077440.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10139..10873
                     /locus_tag="SCH06_000843"
     CDS             10139..10873
                     /locus_tag="SCH06_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077441.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            10912..12054
                     /locus_tag="SCH06_000844"
     CDS             10912..12054
                     /locus_tag="SCH06_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1077442.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12149..13540)
                     /gene="sufB"
                     /locus_tag="SCH06_000845"
     CDS             complement(12149..13540)
                     /gene="sufB"
                     /locus_tag="SCH06_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEG1077443.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13545..14015)
                     /locus_tag="SCH06_000846"
     CDS             complement(13545..14015)
                     /locus_tag="SCH06_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEG1077444.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14002..15237)
                     /locus_tag="SCH06_000847"
     CDS             complement(14002..15237)
                     /locus_tag="SCH06_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEG1077445.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15234..16520)
                     /gene="sufD"
                     /locus_tag="SCH06_000848"
     CDS             complement(15234..16520)
                     /gene="sufD"
                     /locus_tag="SCH06_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEG1077446.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16533..17306)
                     /gene="sufC"
                     /locus_tag="SCH06_000849"
     CDS             complement(16533..17306)
                     /gene="sufC"
                     /locus_tag="SCH06_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEG1077447.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17503..18351)
                     /locus_tag="SCH06_000850"
     CDS             complement(17503..18351)
                     /locus_tag="SCH06_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEG1077448.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18375..19061)
                     /locus_tag="SCH06_000851"
     CDS             complement(18375..19061)
                     /locus_tag="SCH06_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077449.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19054..20088)
                     /locus_tag="SCH06_000852"
     CDS             complement(19054..20088)
                     /locus_tag="SCH06_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1077450.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(20151..20407)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20483..20821)
                     /locus_tag="SCH06_000853"
     CDS             complement(20483..20821)
                     /locus_tag="SCH06_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEG1077451.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20823..21179)
                     /locus_tag="SCH06_000854"
     CDS             complement(20823..21179)
                     /locus_tag="SCH06_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEG1077452.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21185..22372)
                     /locus_tag="SCH06_000855"
     CDS             complement(21185..22372)
                     /locus_tag="SCH06_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEG1077453.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22563..23408)
                     /locus_tag="SCH06_000856"
     CDS             complement(22563..23408)
                     /locus_tag="SCH06_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1077454.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23642..24607
                     /locus_tag="SCH06_000857"
     CDS             23642..24607
                     /locus_tag="SCH06_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEG1077455.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            24984..26027
                     /locus_tag="SCH06_000858"
     CDS             24984..26027
                     /locus_tag="SCH06_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HEG1077456.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26089..26553)
                     /locus_tag="SCH06_000859"
     CDS             complement(26089..26553)
                     /locus_tag="SCH06_000859"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEG1077457.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26799..27746
                     /locus_tag="SCH06_000860"
     CDS             26799..27746
                     /locus_tag="SCH06_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1077458.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(27957..30029)
                     /locus_tag="SCH06_000861"
     CDS             complement(27957..30029)
                     /locus_tag="SCH06_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEG1077459.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(29962..30339)
                     /locus_tag="SCH06_000862"
     CDS             complement(29962..30339)
                     /locus_tag="SCH06_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEG1077460.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30468..31046)
                     /locus_tag="SCH06_000863"
     CDS             complement(30468..31046)
                     /locus_tag="SCH06_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1077461.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31178..32470
                     /locus_tag="SCH06_000864"
     CDS             31178..32470
                     /locus_tag="SCH06_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEG1077462.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32530..33648)
                     /locus_tag="SCH06_000865"
     CDS             complement(32530..33648)
                     /locus_tag="SCH06_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEG1077463.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33662..35083)
                     /gene="arcD"
                     /locus_tag="SCH06_000866"
     CDS             complement(33662..35083)
                     /gene="arcD"
                     /locus_tag="SCH06_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HEG1077464.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35329..36450)
                     /gene="mnmA"
                     /locus_tag="SCH06_000867"
     CDS             complement(35329..36450)
                     /gene="mnmA"
                     /locus_tag="SCH06_000867"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEG1077465.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36854..37453
                     /locus_tag="SCH06_000868"
     CDS             36854..37453
                     /locus_tag="SCH06_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEG1077466.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37591..38877)
                     /gene="efmA"
                     /locus_tag="SCH06_000869"
     CDS             complement(37591..38877)
                     /gene="efmA"
                     /locus_tag="SCH06_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HEG1077467.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLTGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39148..39492)
                     /locus_tag="SCH06_000870"
     CDS             complement(39148..39492)
                     /locus_tag="SCH06_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEG1077468.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39629..40774)
                     /locus_tag="SCH06_000871"
     CDS             complement(39629..40774)
                     /locus_tag="SCH06_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEG1077469.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
BASE COUNT        11755 a         8621 c         7169 g        13392 t
ORIGIN      
        1 aaaatttttt cactaaaatc actacctgaa acagtctaaa acacttatat atcaacgttt
       61 aatgaaacta tctccgtttc atttcagata caaataaata tagtcgggct ccaaatccga
      121 aaaaaaatac ccccagtagc ttatcctaag ctactggaga tgtataagta cggtcatata
      181 acaacggggt agggtaaata aatgaaaaag atggaagaat cattattcaa taactttttt
      241 aaatacttcg ttgtaatcag ttacctgtcc gttcttaaat accacagaat aatctttttt
      301 cccattttca agtaaccgaa gtggaatgtc tttaccaact tgctctgtca ctgcattact
      361 gatacctgtt agattagcta ataaatctga taaagattga gcatctgtag aaatctctgt
      421 atcagtattt atcgtgattc ctttatcttc atttacaagc ttccaagtag gtggtatagc
      481 tgtgtatgtt tcgatgaatg aatcaattct ttcatctatc gtcttcccag tatctacttc
      541 tgtctcatta ctcttagatg aatcgattct ttcatccatc gtctgctccg taactgcttc
      601 tgtctcatta ttctcaccgg aaactctctt cacacccaaa cttatatatt gtccatcttt
      661 agtgtgcata gttaaaattc ccacgctttt actaataaat tcactataac cagttctttc
      721 aatagagact tcaatgtatt tcacactatc atactcaaaa gaaaaataga catgtaaaag
      781 cattttgttg tttacatcta cataataatc ctttgactct acttgagacc ttcctatacg
      841 gaatacagct ttactgtctg atatctctat accagcatcc ttattattaa tctgccaatc
      901 tccaagtagc tcttctggca agctagtagt ttcttgtgaa cactttacca cttcactggt
      961 agaggtcgaa acattcacct ccgcactgtt agaagaattt tccaaggaat caggagcctt
     1021 agcacaacca acaagtcttt atatattgtg cagccgatat tttcttcatt cagtacaccc
     1081 ttgaaatatg cagtgttaga taaagcagtt cgtcctgatt tgctgaggca cccatctctt
     1141 cttgaacgta ctccttgatt ttcaaggccg cccgatactc tttcggaaaa cgctgcttca
     1201 ctgaagccag caaaaaatca tccttctccg gcaactcttc cttcttaatc attcgggcaa
     1261 taaaaaactg taaatgcgtc acaaatctta agtaaagcat cgaatcttta tcaacctttt
     1321 tttcgggaaa cagatatcct agcatagcca agatatcctt tagtgctctt accgagagca
     1381 tggtttcttc catatttgct tgttcacttt gggcatttac aatgtgaaac gcaatgtttc
     1441 cagcctcctc ttctggcaac tgaacattca tttttttgtt gatcaattgg atagcatagc
     1501 agccgatctc aaattctttt gggtaatact tttgaatttc aatcagcagg cgattttgaa
     1561 aaacaatgcc tttttgactg cgttcaatgg catgcttcaa gtgatcaacc aaggtaaaaa
     1621 atagactttt attcagctta aagtcaaact tggcgttggc ataatcgata attcgcttga
     1681 cgcaaataat tagatcatcc ggagcagcct caaacagttt aatgtaatcc ttttttagag
     1741 catcagaaag tgaatctaat ttaaatactt tttggatttt gtcagccgga accaaatcgc
     1801 ctttctttag ttgaaatcca atccctttcc ccatcaaaat tacttctttg ccttgcttat
     1861 ctaagcaaag aattaaactg ttgtttaacg ttttaattac tctcattaga ttcaccgttc
     1921 tctctaagct aagccatttc ttgcgattac tttttgatac caaaagaagc tttctttttt
     1981 tattcgtttt aattctttaa gattctcatc ggttcggtca acatatataa aaccataacg
     2041 cttattgaag ccttgatggg tactaacaac atcaatcgct gaccaaggta aataaccaaa
     2101 aacatctaca ccatctgtta aagctgcttg aatagccaga atatgtttgg ctagataatc
     2161 aattcgatcc tggtcattaa ttcgtctatc ttcctcaact atgtcgggtg ccccatagcc
     2221 attttcagta attaaaatag gtaaatcata gcgatcgtac aatttcctca atgttaatcg
     2281 tagtccagta gggtcaacta cccagccata tggcgtttta tctacataag gattttcagc
     2341 tgcccggtag acaccttctt ctcccaacat gatctgttga tcccccgctc tagcggaaac
     2401 atctgatccg tcatttttgc tggcagcgat ggtggcagtt gaataataat taatcgcaat
     2461 aaaatcgggt ttaccggagg ataaaattgc ctgatcctct gcctcaattt taggatataa
     2521 tccacgatca ttcaaatagt tttcaaacaa ataattgtat tttccccgaa ctgctacatc
     2581 taagaaagac cagcctctca atgtttccca attatgggct gcaattgcat cttctggact
     2641 ggaggtagct tgatacatag ccgttaaatt gattgctgga ccgatttttc ctttaagatt
     2701 caactgatga tacaagtgaa ttactctagc ttgagctaat aaaacatggt gattaatttg
     2761 aaagagttct ttttttgaag gcagctctcc acttggtggc aaaccaatcg ctccaggatg
     2821 aaggatcatc gtgttttgct cattaattgt cagccaatag ttcaccttgt caccatactc
     2881 agtaagcaat acctgtacat agtccacaaa ataatcgata gttgctcgat ttaaccaacc
     2941 gccctgctcc tctagaaaat aaggtaaatc gaaatggtac atggtgacaa tcggttcgat
     3001 tccctgattc aggcattcat caattacttg atgataaaaa gaaattccct tttgattggt
     3061 tttattattt tcaatatcca taattcgcgt ccaagcgatg gaaaagcgaa aagcttttaa
     3121 gcctaattct ttaaacagct gtatatcttc tttatagtga tggtaaaaat ccgaggcaac
     3181 ttcaaaatta gctacccctt ctgtatgctg atacttgtca ataatagacg gttgtttccc
     3241 atcctcctga taggcaccct ctgcctggta ggcactaatg gaggcacccc ataaaaactt
     3301 ctctggaaat gctgaaagct gtttgtattg cacaaaaatc ctctccttaa ctaatttgca
     3361 tcaatggttc gtgttccttt aagcttccgc ttgcttcact aattcctgcg taattttcac
     3421 tgttggtcac taccacaatc actgtatcat cgtagccagc gtttctaatg gcagcgaaat
     3481 cggcgttgat taataattgt cctgctgaca cctgatctcc tgcttttaca aatacttcaa
     3541 agggttcccc ttttaaattc acggtgtcga tccccacatg gatcaataat tcaatacctt
     3601 ctttagaacg tagaccaatc gcatgtttag attctaaaat agtaatgact tctccctcaa
     3661 caggtgaata aatgctgttt tcttctggat gaatggctac gccctttccc aatagtccct
     3721 tagaaaagac agcatcgttc acttcagaaa taggacacac ggttcctttt accggatttt
     3781 caacaatgac tgcttcggct attgccgttt gctctgattc atcagaagta tcgtcaaatc
     3841 caattagata agcaatgata aaggttgcaa caaaggcgat tacacacgta ataattgcgt
     3901 gaacaatatt cattggattt tctccaataa aggctggtaa ggctgctaag ccaggggaaa
     3961 caaaggcata tctgactaaa ccgctcaagc cagcatacaa accagcaatt gcaccaccaa
     4021 tcatggaagc aactaatggt tttttcagct tcaaggttac tccatagagt gaaggctcag
     4081 taattcccat taaagcagtg atcccagtgg acacagctag ctgcttcaac tctttgtttt
     4141 tagttttcgc ggctacagca aaggtagcac ctgattgagc aatattagaa gccagcattc
     4201 ctggcccatt gatcatttca gaacccgtac tgctcaattg catagtagcg attggcgtca
     4261 ttgcccaagc tgtacccgta accaccaaaa atggctgcaa accacccatc aaaaatggaa
     4321 ttaaccaagc tgctttgccg ttaatccatt cagcccccat tgctataaga tcgttcagca
     4381 acgttccaaa cggtccaatg acaaccaacg ctaaaggccc cataattaaa aataccagca
     4441 tcggcttagt aaagaattta ataaacgaag gcgaaattcg atccgcaaag ggctctacat
     4501 aggacatgat ccaaacagta aagataatcg gtaaaactga tcccgcataa tctgcagcta
     4561 ataccggaat tcctagaaaa gaaacggcat cgccagtaga aaaaagctgt gaaatatttg
     4621 gatgaagcaa aatgccagca acagtaatcg ccaaaattgg gttgacatca aactttatgg
     4681 ctgccccata ggctaatagt actggcataa aataaaaggc tgcatcagca atagtattca
     4741 aaatgatgta agtttgacta ctgtctgata gtacaccagt caaagtcaag acggccaaaa
     4801 tggcttttac catcccggca cctgttatag ctggaatcat cggtgtaaag gtggtagaaa
     4861 tgacactaat caatcttgaa ataatacttt cttgattgtc tgaagagggg ccctttttaa
     4921 ttgaagttcc cacttccttt tgaatttcct tgaaggctgt ttggacttca ttgccaatca
     4981 ccacttggta ttgtccaccg ctatccacca cactaattac accaagtgtt ttttctaagg
     5041 ctttcgtatc ggctttcctt ttatctttga gttcaaaacg cagtctggtg gcacaatggg
     5101 ttaagctgac cacattttct tttcccccaa cctgttgcaa tacatttctt cctacttctc
     5161 tgtaatccat tattctctct ccttaaagca gtaaaaaaga ccaagtcaaa ccacgcccca
     5221 atcaacattg aagtgttagt ttgtcttggt cttgcctgca taatcagtaa catgccaata
     5281 acgttatttt gctgtaatcc aataatagca cattatgata gcgcaatcaa cagggaattt
     5341 aattttttat cttttcgttt gaccgtatag ggtaatataa cagttagatc acatcaacta
     5401 gggtatatct gcgtatactt actgctaaaa taagtatatc taatattaac tataccagta
     5461 aaaccattcc tacataacca gcgggaaatt cccaaaatcg tgaaagcatc aaaaatgcat
     5521 ataacggatc acacaacttc aacaattctg ctcttgggaa aaattgatga atttggtgag
     5581 taaaggatgg aataaacagc attccaacaa tataggcaac aatagtgata cttgtttttt
     5641 tggtaaaaat cagtaagcaa tagccaattt caatcattcc gagatataaa ggtatcgata
     5701 gaatgatttg ggctagtatt cttaaaaatt aactagcaaa tgtttaaact gatttatttc
     5761 taatctacat gtagtaagta tttcaattcc accaattatc aataaaaata ccaaacatat
     5821 ccataataat tttttctttt tcatttcttt tatattgtta taacagtgaa taacataaaa
     5881 attcccgaca atcattgtaa tatttttttg tcacctgtat tagtatttaa tttataggaa
     5941 actataaaaa ctccctagtg aatttacacc tttgggagtt cctgtttgga cggtatgcat
     6001 aatacattta aatcaattta acattaacac ctcagcatat ggtatctcca catatatacg
     6061 gtctttcttt ggatagtact caatatttat gttgatagca cttccattgt ctaatatagc
     6121 tttagcccgg tatgtgttat ctccattttc atgagtaatc gtcacatcat cacatgatcg
     6181 atttaagttg tactgttctt gtaaaatctg tgttaccaat ggttttgatg acttctctaa
     6241 tccagatgta cctgtcattt ttgaaaaaat aatacctata atagccaaga caacaatacc
     6301 tataatgaca aacttcttgt tcatatttac tttattcaac tttttatctc ctatctccaa
     6361 aataatttgc tcttatccct cttatcagta cattgacatc cctaaaagta caccaaagat
     6421 tgctccagct acccctgcta tcatcaaaat cgtacccatt ttctcatctt tttctcgata
     6481 taagtagccc ataataacag caacagcacc aaatacaaca ggaataaatg ctaacgatac
     6541 taccatagaa atccaaccaa taatcaaata cagcttccct gtctcttgtc catgtacgat
     6601 ttgttccttc atttcattaa ttgtctgctc agtacttttc tttactgtgt ctgttccggt
     6661 tgtctcatct gtttcttgta gtgctccaca aaactggcaa tacttacttt catctgttat
     6721 ttctttgcca cattttctac aatacatgtc ttctcctcct aaaatcattc aattgcttat
     6781 tagttaactg tttactttat taaatacatc agaaaacagc tcattcattg gtacacttaa
     6841 tatctcagaa agcatcttca tttgataggg tttaggaatc gttctccctg tttgccacga
     6901 acttacacat tgctgtgtaa cattcatttt ttttgctaac tccgtttgag aaagtccttt
     6961 ttcttttctg tatcggctga gattacttac ttttttcatg attctcccct cctgttttat
     7021 tatatacaac aatatgatgt atttcaactc ataaaatata aaaaacttca aataccatta
     7081 caaatacaac aacttgttgt actatactga gatgggggtg tattaatgaa acagaaacaa
     7141 tatgcaaagg tcattagaga aaagcgaaaa gctctcgggt ggacacaaaa agaattagct
     7201 gaaaaaatct tctctacaca acaggcagta gcaagatggg aaaattctgt aacagagcct
     7261 aacctcgata gcttaacagc tctttctaga gccctaggaa cccctgtaag ccattttcta
     7321 gacaatgttg tcgtagatta tgaggaagag tttttggctc tctatcgttc tcttagcact
     7381 gaagatgcag ttcgaacaat tgactatatg aagctattaa aaaggcaaga aaatgaacgc
     7441 aatcagctat tgaaagattg aaaaataaat aacccaccga actttaacgg tgggtgtatt
     7501 gagatgaaat aagattaaga gctatggata acctgtctag tttaatacaa ttgggtcttt
     7561 tctcttcctt actctccgtc catcatctct tgttacactt gtaaattgat acagaggaac
     7621 tatcccagct cctgataata tcaattcttt tattgtttca tctatccctg cccctttcgc
     7681 taaatatatt aaaaaactac tacttgcttt cacattgtat agtttcttaa tatccttaga
     7741 agctcgttca agagtgaatc cttgtttaac aaagtagcct ctgtttttta ttaaagcatt
     7801 tttcacgctg ttatccccaa cattacgtag gcgttcacaa acagtgttaa taagttcttt
     7861 ctctgtcatt agatatgtcc cttgccacga taagccctgt aaaacttcat gtgcttcatc
     7921 taaaatcaat tgtttttcct tgctgagttc tgatcgggaa ttttgaggaa atactctttt
     7981 agcctctttt tcgttaaaac atatcttaac ccattcataa gaaaaatatt gatatgtaaa
     8041 atgaattttt tccagaagtg gaaggatatc ttcattcaat ttttgaatca cagaagttgc
     8101 attaaaaacg tctaatcgat agacattgct tctcttatga ttaaagtttc ctaacgcttt
     8161 ctcttccttt aacctattta ggtattcgag catcttcaaa ggaacatctt catcatctaa
     8221 tttttttatc aatcctataa aagtcataag tgatagtaac ttattacatt tatctatgtc
     8281 ataagtttta ccatagtaag aactcatttt tttagctaat tgttcccccg acaaaataca
     8341 agtcacactt tccttactat catcaaaaaa attaacatca gaaagcaaga catcatagac
     8401 acgtcgcatt tcctctagat aattccttat tgtcctgaaa agtttgtctt tcattgattc
     8461 aagagtgtca aaaagtactt ttgattcctc tttcaatttt cgaaaatgtg taggatacaa
     8521 gtctaggttc tctaatagcc aattaaatgt ttctacccga ctgtctttct ttaaaattag
     8581 catcacaact ccaataaaat tttcactgat atcacaatta ctggaatgac aataaaaaat
     8641 ggaatgccca gttttactgg taaaaatact agcagaggga ttatgatcgt tgtgaaacag
     8701 acatcttaag tttttacttg acttaagtaa tttattcata tcaatggtta acaatctttc
     8761 ataaatctca ttaaaagaca tgtcggagga atcaaacagg cagtctttaa accactgttt
     8821 catttcttct ttgtcgtcat tttttatcaa cttaacaaaa tcggtttcat tgactagttc
     8881 atactctctc cctgaatcac tttgacaatt tttagaacat gtcatggtaa aatcaatcgg
     8941 aagctcagta atatctaaca tgttgtcttc attaattatt atcactgcat ctgacttata
     9001 tcctccaaaa aacattctat tcgaagcatt tacattgtca tcacacccgg ggatgttctt
     9061 tttcaagtat tcgtaaacag caaccatttt accatagtca gtaattgctt cttttaatag
     9121 aaagacaatc ttgtattttt ctagattttc agagtaccga atactttttt gtatcgcaaa
     9181 cgcagaatta tgaactaaat tgatagataa aaccttttct acgcttaagt atctactatc
     9241 atctttactc aaatctacta ccttcccctt ctcatcttta acagtgttat cgacatccag
     9301 aataattact ctggtttcca caaaactctc cttgtcattg cctttattct ttgtcttgct
     9361 tggaataaat gattgtgatg aatttagtat ctctacaaac tcatctcttg taacttctct
     9421 atagttatct aaacacctat ctcttacatc agttttttct ttttttgtaa ctggcttctc
     9481 taataatttt tcttgatcta cataaattgg aatattaatc attgatgttt ccatttgtgt
     9541 ttcctcctta taaaattctg ttaaagacta aaacatacag ataataaaaa caaactcttt
     9601 attactatat gttttagtct tatttgttta ctcaaccttt ataccgttcc atgaaactat
     9661 caatatcaga ttttttaaat ctaatgaccg tatcaatttt tataacaggt aacccgtatt
     9721 gagaaacata ttttctaatc gttcctactg atacacctag atattcactt gcctgctgat
     9781 agtccatata ctctagagtg actccagaaa taatgtcttc tagcataggc tttagcactg
     9841 taattatctc tttcacttgt tgttcaactt gtatagaaac aatgctatca atgatttgta
     9901 gagacatatt tccccctcct ttcgtgattg cttgaacaaa ttttctaaga attatcttcg
     9961 tattttttgc tcaaaataaa agtattttgt tattaaccga ttaatcaaac aaaaaatgat
    10021 taccagttca tcgacataca cataatacct cgataaaaaa ggggtgtcaa cagctttgta
    10081 aaatttattt gcaacacccc ttttttgagg tatactaatt ttaggaggtg tggtcaatat
    10141 gataaaacgt ccaccaataa attatttaga acgaaaaaag atactcggaa caaaaataaa
    10201 agctataaga aagagtaaaa aattaacaca accagcattt ggtcttatga ttaacaacgg
    10261 tcaattaatt gacaaaaaaa ctatctacga atgggagaag ggaacctatt taccaatacc
    10321 agagcgatta tcccgaattg ctgatttggg aaatatgagt atagaggagt tagtttgtgg
    10381 caatgtagaa gaatatattt tgggaattat tctttataga gatagcattg tactagatgg
    10441 tataacattt ccagataaaa acctgttcca gcatcttcgt caacagttcc caccagtaca
    10501 ctctaattta gatacatggc tggatagata ttccaaatta gaaccagaga tgcaagaatt
    10561 tattgctaac aagacttgta ataaagttaa aaatgaaaaa attagtcttt tcaatatctt
    10621 aaaaatagaa gaattattca tcaatgctat tgtagaagaa tttgacaata acattctttt
    10681 cctcactagc agtatagaag aactactaga aagaatggta gatgaatggc tacctattca
    10741 attgaaagac atgtcttatc ccgaagaagc tgtgagagaa attactgata atataaacaa
    10801 gctagaacaa acgatttcat caattgggaa aaaatacact aagaaaaaaa tgaagggagg
    10861 tgataccatc tagtggtaag tactccttgt aaactaagag gagatgattt aatggcaaaa
    10921 atatcaaagt acaaaaagaa aaacggtcaa gtggcgtgga tgtataaagg acacattgcc
    10981 accgatccac gaactggtga aaaaataaat actacgagaa gaggttttag tagcaaacaa
    11041 gaagctcaaa aagattatga cgagtacaga catcaaatat tatacggtgt taaaaagaaa
    11101 gcacctgata tgacatttga agacctgtat aatgaatgga taactcatca gcgtaccagt
    11161 gttaaagctt caacaatcgc aatctcagta agatacgcaa ataatcaaat acttccagca
    11221 tttggtaagc ttaaactatc gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa
    11281 tggcacagta aatatgaaag ttacgattat atgagaaaac agactgcaca aattttacgc
    11341 tacggggttg caatgcaata tattgacaat aatcctatgg aaaaaacact tcttccacga
    11401 aaaaaagagt atgagaaaaa tcgtaaattt tactcaaaag aggagcttaa taatttactg
    11461 gatgctttta aagattttgg taacatgaaa caatacgcct tcttcagatt attggcatac
    11521 acaggtatga gaaagagtga agtactcgct ttacagtgga aagacataga cacgtttaat
    11581 aaagaactac atgtcaataa aactcttgct gtagatgaat ttggtaaagt tataattcaa
    11641 tctccgaaaa caagagcttc tagacgagtt atctctttag atactgagac tctttctatc
    11701 ctcaacaact ggaaattaca gcaaaaagaa gagtatttaa aacttggata caatactagc
    11761 tctaaagagc aacatgtttt tacaacagtt aaaaacactc tatacattcc aaacactgtt
    11821 aatgattggt taagatatat tttgaaaaaa tataacttgc ctcgtattac acctcatggg
    11881 tttagacata cacatgctag tttattatta gaagcaggag aatctgtcaa ggtagttcaa
    11941 caacgattag ggcatgaaaa tagtaaagtg acattagaca tctatgcaca tattacaaat
    12001 aatgcaccta agaaaacagg tcaagacttt gctgatatga tggctcatca gtaaaagagc
    12061 tggtcaaaat ctggtcattt ctagtataca ggcaaaacaa aaaagctaga acccttatat
    12121 atcaagggtt ctagctccta taacaggttt acccaacact gccttccatc tcataactga
    12181 tcaatcgatt gagttcgact gcatattcca ttggaagttc tttggtgaat ggttcaacaa
    12241 agcccatgac gatcatttca gttgcttcag attcggtcag gcctcggctc atcagatagt
    12301 agagttgttc ttctgagatt tttgagactt tggcttcgtg ttctaaagag acttggctgt
    12361 tgtggatctc attgaatggg atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt
    12421 cacattcgat atgagagatc gaacccgcac tgtttttggc aaaggttact tgtcctcgat
    12481 agtttacttc tccgccgtct tttgaaattg atttagagac gatagagcta gatgtatttg
    12541 gtgcattgtg gatcattttt gcacccgtat cttggatttg gtttgctcct gcaaaggcga
    12601 tggagagcat ggtgcctcgt gcaccttttc catctaagta aacacttggg tatttcatcg
    12661 ttgtttttgc acctaggttt ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg
    12721 ctcgtttggt tactaagttg tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc
    12781 aatacgcatc ttttcttgta aagatttcta cgatggcggc atgcaggctg ttacttgaat
    12841 aagtaggtgc cgtacaacct tcgacatagt ggatgcttgc tccttcgtca acaatgatca
    12901 gcgtacgttc gaattgcccc gtgttttccg cattgatccg gaagtacgtt tgtaatggaa
    12961 catcgacttt gacgcctttt ggcacgtaaa taaaggtccc acctgaccat acggctgaat
    13021 tcagcgctgc taatttgttg tcggttggcg gtacaagttt tgaaaagtac tctttgaata
    13081 attcagggta ttctttcaaa gcagagtcag tgtcagtaaa gacgattcct aacttttcga
    13141 attcatcttt catattatgg tacacgactt ctgattcata ttgtgcggaa gcaccggcta
    13201 gataagctcg ttcagcttct ggtataccaa tcttttcaaa tgtatctttg attttttctg
    13261 gtacgtcttc ccagtcacga gcgggtttgt cacttggttt ttggtaatat ttgatggcat
    13321 cgaaatcgat gtctgaaagg tcggggcccc atgtttgcat tggcattttg ttaaatgttt
    13381 ctagagattt cagacggaat tcaagcatcc attctggttc gcctttgatt cttgacatct
    13441 cacggatcac ttcttctgtc aagccttctc ctgtactgaa aaccggttcg acatcatcgt
    13501 gaaacccgaa tttatattct tctaattctg gtacgcccat gttctcactc ctcttccttg
    13561 tggtaatgat ggaaagctgc ggtaccatcg ttttccattg cttttcctag tgctttccag
    13621 gcaagtgtcg cacatttgat ccgagcggga aatttagcta caccaccaag catagcagca
    13681 tcgcctaatt ggtcgggatc tttgacttct tttccttgga caagctgtag aaagtctaca
    13741 gttaaatgtt ctgcttcttc tattgatttt ccgatgacgg cgtctgtcat catcgaggca
    13801 cttgccgtac tgatggagca gccactgccg tcaaaggcga tatttttgat gattccgtct
    13861 tttacatcga cttgcaattc gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg
    13921 cttgtcgagt cagtcaagct tccacgatga tgcggatggg aagaatgatc caagatcact
    13981 tgacggtata aattgtctaa tttagatagt cccatgttgg aaaaactcct ttgttgccat
    14041 gattgcttca actaaacggt cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg
    14101 agcagtcgct gatacttcaa ggtacttcaa tagcggttgc gcacaatgat gacctgctct
    14161 gacggctacc ccttccatgt ctaaagctgt cgcgacatca tggggatgta acccatccaa
    14221 attgaatgca acgactcctg tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc
    14281 atcaattgct tgtaattttg gcaacacata agcggctagt tcttcttcat atcgatggat
    14341 attgtccata ccgagttttt gcaaataatc gattgcatgg cctaatgcga tagcgccggc
    14401 gatatttggt gtccctgctt cgaatttcca aggtagttct ttccatgtac tgtcgtataa
    14461 ttcgacaaaa tcgatcattt cgccaccaaa ttcaacaggt tccatttctt ctaaccattt
    14521 tcgtttacca tataaaacac caatacctgt tggtccgcac attttgtgtc cgctgaaagc
    14581 aaagaaatca cagtctagtg cttggacatc aatggccatg tgcggggcag attgagcacc
    14641 atctactacg atgaccccgc cgttttcatg gacaagttca gctaattctt gaacaggatt
    14701 gaagacacct aagacattgg atacatgagc aatggagacg attttggttt tgtccgtaat
    14761 ctttttcgct gcatcctcca tatccaggaa gccttcttct gttagttcga tatatttcaa
    14821 gacagcacct gttcgttttg ccaactgctg ccacgggata acattagaat gatgttccat
    14881 gtaagagagc actatctcgt ctcctgcttt gatatagcgg tcgccgaagg ttctggctac
    14941 ccaattcaag cttgtcgtcg taccacgagt aaacagcact tctgctgttt cttttgcatg
    15001 gatgaacgcc cgtacttttt ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa
    15061 cgtatggaca ccgcgatgaa cattggcgtt atcgtgttcg taatagtacg ctaatgcctg
    15121 gagtacttgt tttggctttt gggtcgtcgc tgcattatcc agataaacta aaggttcatc
    15181 attgacgtct tgaaataaga taggaaaatc attgcgtagc tttttagcat cgatcatcca
    15241 ttcaacttcc cttcgattac ttcgactaat tctttccgaa cttgttctac agggattgct
    15301 gttaagacag aaccgaggaa tcctcgaatc actaagcgct ctgcttcttc tttatgcaat
    15361 cctctactca tcagatagta catttcttct ggatcaactc gtcctacact ggcagcatgt
    15421 ccagcagtta cttcgttttc atcgatcaaa agaataggat tcgcatcacc acgtgcttta
    15481 tcagaaagca tcaagacacg actttcttgt tgggcatctg caccttttgc ccctttcaag
    15541 atgtggccga taccattaaa ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa
    15601 atatgcccga tcgtatgagg ggctttattg gttactcgtg tatcgattcc ttggatttgt
    15661 ctgcccgagc tgattgccac gattttgact tctgcgtgtg caccttctcc tgctaaatct
    15721 gagtcaaagt cagcgatcac atgaccgtca ttcatgacac caattgccca gtcgacagaa
    15781 gcatctcgta aaatgtgccc acggcgattc atataagaag taatattttc tcctaattga
    15841 tctacggctg aatatttgat ttttgaacca gctttagcga tgacttccac gatgatatta
    15901 cctgatgatt ttgctacttg ttctttggtt gtctggaaac gttccagata agaaaattca
    15961 ctatgttcat ctgccacgat caacacatgc ttgaagaagt gctcatcgga tgcgccatct
    16021 tgaatgaata aggactcgag tggttcatcg atcacgacat ttttaggcac atacaggaaa
    16081 ataccgctgt tcataaaagc tacatggagt gcagtcaatt ggtcttcgtt catgtttact
    16141 gcttttttca tataatattc ttggactagt tctggatatt cgatcattgc agtgaacaag
    16201 tcggtaaaaa tgactccttt ttctgctaat tccacaggca gttgttcaaa aatcgtccat
    16261 gaaccttgtt ggacaagcac aggattgtct ttcattgcat caaatgccgg aatcgtgcct
    16321 gtttcactga tggtttgtgt ttctttcaca tcaaataacg accagcgatg gaatttcacc
    16381 cgatcgatat gcggcaatgg cagttcatct gctttcgcta gtgcgtcttg acggaaggtt
    16441 ctcatccaat caggttcgcc tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg
    16501 agccagtttt tttctttcat tcttgctccc ccttacgctt cttcttcttt atagtcgatt
    16561 cctaattctt tactgatacc agcgtagcct tctgcttcca gacgtttagc taggtcagca
    16621 ttccctgtca tgactactcg gccttccatc atgatgtgaa cgacatcagg tgtgatatag
    16681 ttcaataatc gttgatagtg ggtgatgatc aatgcaccga aattgtctcc gcgcatttca
    16741 tttactcctt tagcaacgac tttcaaagca tcgatatcca gacctgaatc gatttcgtct
    16801 aaaattgcaa atgtaggttc taacatcaac aattgcagga tctcattccg tttcttttct
    16861 ccgccagaaa aaccttcgtt cagataacgt tcagccattt cttctggcat atttagtaaa
    16921 gccatttttt catctaactt tttcaaaaat gccataacag aaattttgtc gttttcatca
    16981 cgtttcgcat tgatcgctgc acgcatgaat tccgcattcg tgatacctgg tatctcactt
    17041 ggatattgca tagctaaaaa taagccaagt cgcgcacgtt catctacttc caagtctaaa
    17101 acatttttcc cgtcaaacaa aatttcgcct tctgttactt catagtttgg attgcccatg
    17161 atagcggcag ataaggtaga ttttcctgtg ccgttaggtc ccatgatggc atggatttct
    17221 ccggttttca ttgttaggtt tacgccttta aggatttctt tttcctcgat cgacacatgt
    17281 agatttttta tttctaagac agacatgcat tataccccca aattctcttt cgttctcact
    17341 cattttagac taattgagaa tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt
    17401 tatttattat taaacaattt tgatttctaa attagaatag gtataaaaaa gatgagaaat
    17461 aagccattac agacttattt ctcatctttt ttgttccata ccttattttg catcagcctt
    17521 tactggttta acagagccgc cccatttgtc tgtgatccat tcttggactt ctttgcggtg
    17581 aagcacttca atcagttttt tgattttgtc actgtcttca tcacctttac gagtcgcaat
    17641 aatattcacg taaggagagt tgtccttttc aagcaatacg gcatcttcta atggattcaa
    17701 ccctgcgccg taagcgaagt ttgcgttgat tgcaactagg tcaccttcat cattttggta
    17761 cgtagaagct aaaagtgatg ggtcgatcgt atggttgaac ttcaagttct tagggttttc
    17821 ttcaatatca tcgaatgttg ctgtttccag atctactcca tctttgactt tgactaagcc
    17881 agcatcttgt agaattgtga tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat
    17941 tgttgcacca tcttttaatt cggaaacatc tttgactttt ttagagtaca agcccattgg
    18001 ttcgatgtgg acagcaccgg cattgacaaa gtcatatcct ttttctttga tttctttgtt
    18061 caaataagga atatgctgga agtaattggc atcaatgtcg ccttcttcca aagattggtt
    18121 cggtaataca tagtcatcga atttgacgat ttcaagatcg attccttcat ctttcaataa
    18181 tggtttcaca tgttccaaaa tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt
    18241 cgtgtcgtct gctttatttg ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa
    18301 tcctacagtc agcaaaagcg ctgctgcaaa tccaaaaatt ttctttttca tatcctacat
    18361 ccccctatat cctattatct tttgtctgtt ttcttagtta agaaatcacc gattccttga
    18421 acgataaata cgattagtaa aataattaaa gtcgcaacga atgtcactgt tagattacca
    18481 cgctggtagc cttcctgcca agcaagacct ccaagtccac ctgcgccgat cgcgccggcc
    18541 atcgcagtaa atccgatcat cgagatcgtt gtaactgtta atccagaaat caatgcggga
    18601 atactttcag gtatcaagac cttccagatg atttcccagt aacttgctcc cattgcatct
    18661 gctgcttcca gtacaccagg gctgacttca cgaaaagcaa tctctactag acgggcataa
    18721 aatggtgctg cggataaaac aagagctgga atggctgctt gcgcacctag catagtgcct
    18781 acgattgctt tagtaaatgg aatgatcaaa accatcagga tcataaatgg cgttgaccgg
    18841 aaaatattac tgatgatcga tacgattcca taaatgattc gagcatacgg tttgtttttg
    18901 cgtccaatag agtaaaggat caatcccaaa actaatccga tgatcgtcac taagaccatt
    18961 gagattaatg tcatatatag tgtatcaagg atagcctgat tcatcgtttc cgggttgatt
    19021 tgtttaaaat ctagatatgt ttctgaaaag cttttatcca cgatggatca cctcaattcc
    19081 tactccttgt tctttgatga acacttctgc ttgatctaat tctttggttt caccagtcat
    19141 caagacagtc aatgaaccaa aggaaccttc tttcacttgt ttgatctttc catacacaac
    19201 gttgacatcg atgttatagc gtcgaatcgc ttgggaaatg actggctcgt tggcatttct
    19261 ttcgctaaag gtcaaagttg ccaaacggcc gcttggattt tctttgatga gttcagctaa
    19321 tagttctgtc gaatcagctt ctggttcgat gtcttgttgt acaaagcgtt tggttacttc
    19381 ttttttcggt tgtctgaaga cagtcaatac gtctccttct tctacgactt tccccaactc
    19441 catcacagcg actttgttgc agattttgcg gatcacattc atttcatgtg tgatcaagac
    19501 gatggtcaaa ttcaatttct tattgatcgc taacaataag tctaatactt cttctgttgt
    19561 ttgcgggtcc aatgcgctag tagcctcatc acaaagcagg atctcaggat catttgccaa
    19621 tgctcgtgcg ataccgacgc gttgtttctg tccgccggaa agttgtgaag gatatgcttg
    19681 tccgcgtcct tctaacccga ctaaacgcaa cagttcttct gcccgttctt tacgtttgct
    19741 ctttggtacg ccagctaatt ccagcggcag ctggatattt tcaagtacag ttcttgacca
    19801 taacaggttg aaatgctgga agatcatacc gattttcttt cggaatgtac gtaattcttt
    19861 gttttttaat tttgtaatat cttgatcgtt tacgatcact tcgccgctcg tgggaagctc
    19921 aagtccattc aggagacgga ctaatgtact ttttcctgcg ccagaatagc cgacgattcc
    19981 ataaatatcc cctttttcaa cgtttagtga aacgtcattg acggcttgga tgtttccgtt
    20041 tttcccattg aatgtctttt tgacattcgt tagttggatt aatgacatgc cattcacatc
    20101 tttctcttat gatttttcaa acaaaaaagc cttcgccctc ttgccttaag caaaaggacg
    20161 aaagcttgaa cttccgtgtt accaccttga tttaccgtta cttcgcaata acagcctctt
    20221 ccagtacttg gacttagctt ctttccgtat actgtcgcgc tgtaacgggc actcccgtag
    20281 taagtttgct tacgctcgct tactctgctc taagaccatc ttccatctca ttttcgttac
    20341 ccattttcag caaacagggc tctcttcaaa cgtccgtgac atgtactctt cttttcaaag
    20401 ctttctcgtt tcatatagga ttgcttatga ttatagcaac tggaagaatc agtgtcaact
    20461 tttttcaagt gattttctga ttttataatt cgtcaaattc ttttggatca acatctttga
    20521 aacttaagat ccacgcattc atttcatctg aatcattcaa gatattgata tcttcaccga
    20581 ttttatcatt aacagaagaa actgtacccg ttagcgggct ggcaaattca ttgaccgctt
    20641 tttccgcttc aacttcgatc agaggttcat ctttttttag cgattgtcct gcttttggca
    20701 gattggcaaa cgtgatgtct ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt
    20761 attcttttcc attaaataag atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca
    20821 ttttatatca gttctccttc ataaattttt tcattgaatc caattgcaac aagctggtcc
    20881 tctcgtaaga tcagtggtcg cttgatcagc ataccatctg tcgataagac ttggctcgct
    20941 tttgaagccg taaactcgcc tacttgatct ttcagtccaa gttcccgata tttcatcccg
    21001 cttgtgttga acaggcgacg gattggtact tgactcgttt ctagccaagt ctcaatcgtt
    21061 gaggccttcg gtacttcttt gatcatatca acggtttgat aactaacgcc atgctggtct
    21121 aaccacgctt tggctttttt gcatgttgaa catttcgggt accagtaaaa ggtgtacaat
    21181 tttcttacct ccttgaagat cttgcaggtg cttcattttg gtatctcatc gataatatca
    21241 acccgatacc gatcatgttc cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg
    21301 ggatccctgt taaaggaagt aatccgatat ttgctccaat attctcaaag acatggaaca
    21361 gcagcatcat gatcaaaccg cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac
    21421 acacccgaat catacgatag attaaaataa aatacaagaa aatgacgaat gcaccaccga
    21481 taaagccgaa gttttcaccg ataacggtaa aaatcatatc ggactcacga acaggcacat
    21541 agatattgct tacgttgaat cctttaccaa acaagccacc ggtaccaatt gccaaaagtc
    21601 cttgggccgg ctgataactc attcctgacg tatcatggaa agggtccagc catgaatcaa
    21661 tacgtgcaaa ctgataagat ttgaatccaa ctttataaag caagtctctt ccgccttcag
    21721 tcgtaaccaa gaagatcgtt cctgctccaa cgactactgc caagattact acaggtgcga
    21781 tgatgcgcca agagattcca gacatcagga aaatcccgcc aaagatcgca agaaagacaa
    21841 gcatcgttcc aaagtcatct tgggccatga tcaatgctaa aaccggtatt gtcacgatca
    21901 agagcttccc aatcagccaa aagtccgatt tcatcgtccg ttcttttact tgcgtattat
    21961 gtttagttac gatcagtgcc atcatcaaga tgtacgcaat cttcatcaac tctgctggct
    22021 ggaaagtaaa cgcaccgaat cgaaaccagt ttttagaccc tgttgaagca gctaaattct
    22081 gatcatagaa tttgagcaag agtcccatta ccactaaccc caaaccataa aggtaaggag
    22141 tcagtttcca gatccatttg gaattcaaat gcatgatgac aacgattgct gccgctccaa
    22201 ctaaatacca gacaacttgc atccctacgc ctttcaagac tgctggattg ttcggatcat
    22261 ggctaagtgc tacatataat gagagcagac caatcaaaca taacagaaag actggtaaaa
    22321 tcacgccata atcaatacga ttatcgttcg aagcttttaa ttttttttcc atgtttcatc
    22381 ccttttctta aaaaccatac tgctgattat tatagcggtc cagttagata atggaaagtc
    22441 tttccataga catttgggaa aaattaactt tccgtttgtg cagttgcttg agcaaatgca
    22501 gtacaaaagc ctactgctta tctttagtgt atcatagaac tttttttgat acatgcaatt
    22561 atctaccagc tgagattctc ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg
    22621 atctcttcgg caatctctag cagctgatca gaaaccagat tggttcgttg gatgaaataa
    22681 aaatatcgat ggaaattcaa cggagtcatt ggcacatttt ctggaacaga gcgcttagac
    22741 aaaatcgagc gaccgattcc ttccttcagc aacgcaacaa ttacatcgtt acttttcacg
    22801 atcatcttct tatcttggat attcatctct tcaaaataac gctgcgtgta atgaaaaaca
    22861 ccagagtttg cttctcttac aagccacaat ttgctttttg ggtccccagc gatgactagc
    22921 tggtcttcca tcaaagagta tctttgtacg ccggaagtct ctaatggctt ttcgataaaa
    22981 ccaaaatcgg attcatgttt cgctacttgt tctaatgatt catgagaatt cgtgatttcg
    23041 atctcaaaat gcactttagg aaaccttttg atcagatgtt tcatcaactg aggcaaaaga
    23101 tagacagcaa aggtgtggga agcaacgatc cgacatactt cttcttcatt ttgttcattg
    23161 agcaattttt gctgagtttc ttcccattct tctaacaaaa ccagtgtccg ttcatataat
    23221 aagtcggctt gcttagttgg aagcatctct tttcttccgt tacgttgaaa aagatcgata
    23281 ttcaattccc gctccaactg tttgatttga ttcgagactg ctggttgaga taaaaacagt
    23341 acttctgctg ctctggaaaa atttcttgtt tcatatactg ctcgaaaagt cgttaataac
    23401 ttaaacatgg caccacttcc ataacttttt atgataatta ctataaaaac tatttgattt
    23461 aaatatacaa aaaaccatct ataatagaaa tgtacaacaa aacagttgct gatccaacta
    23521 gtaacttaga tgaagacaat cagctgtctg cttgctcgta atcatacatt cctattcatt
    23581 ttacaatgta ttcgttcatc ttggtactaa aatctattaa ataaaaagga gaatattata
    23641 tatgaagaac tttttgaaaa ttattccgat cccgatctgc gggttgatcc ttgggttagc
    23701 ttcccttgga aatctgttta aagactatca ccatgttgct ttaggcaatc taactggcgg
    23761 tatctctatg attcttatga tattcatttt tgttaaattg tttatcttat tcgaacacac
    23821 gaaacaaacg ttgcatgatc caatcatcgc ctccgtttca ccaactttta cgatgtcact
    23881 catggttatt tgtacttatt ttgtttcata tgaaagtatt gcaccaattg tcaaattcat
    23941 ttggctgtgc gctgttatct tccaagtgat ccttgtcttt tatttcaatt atcaccatgt
    24001 tatcaaagct gatctttcaa ttgaagcaat ttatccaagc tggtttatca tttacgttgg
    24061 atttggggtc atcactgtaa ctgccgggaa cttcttccca cttattggaa aaattttctt
    24121 ttggatttca ttgatctgct atgcgttctt attgccgatc atcatcaaac gtgtcttttt
    24181 cgtaagaaat atggctcatc cgacacgtcc gctgattacg atcgttgcag cacctggttc
    24241 tctttgccta acaggttatc ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc
    24301 attgttcgct ttatctcaag tattgtattt cgttgtgctg tctatgcttc cacgtttgtt
    24361 caagcttcgt ttttatccaa gctatgcagc ctttacattc ccgcttgtta tctctgcaac
    24421 agctatattt actactgttc attacttcaa cagtttaggt atctatagta gcgtattgga
    24481 tttcttaaaa gttgcggaat gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca
    24541 ttacgtacgt ttcttaatta aagaacatag caaacatgga aaatttgttt ctaaaaaaat
    24601 cgcttaataa tcgattcaat aggttgtgaa aaagctgttc tgcatcaagt aataagaacg
    24661 gccaaacaaa aacagctgtt catgtttttg tactggttgg gcttattacc gcagatgcaa
    24721 gcttttgaac accgtttacc aagaggtcgt aaaagaagtg gtcagcttca agaaataaga
    24781 aggaatttac gaaaattgct tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag
    24841 ctacttctgg aacaccgttt attcgaaaca agaggtcgta caagactttt gtcacgacct
    24901 cttgttcttt tgtcaaaata ctggtttagt gctactatgt tcgagtatgc ttttagtatt
    24961 tattgacgaa aggaaccgat caaatgaaat cattgtcaca tccaataaaa tctgtaaagg
    25021 attcagcggt ccgcgaaatc ttacccggtt tactgctttc ttttgccatc gctgccttca
    25081 gcaggcttct tgctatttat ctgccacagt taggtggagc gactattgct attttattgg
    25141 gtattttatt aggaaatact ttttttaaac agcctgttct agcaatcggc acaaaatttg
    25201 ctgaaagcaa actattagaa ttctctgttt ttttactagg tgcaactgtc acagctcaaa
    25261 cgattgctca aattggtgta aaaggaattg tttttgtgtt actgcaaatg tcagtcacta
    25321 tcatcggtgc ttacttgatt ggtaaaaaac tgcaattcag cgatacttct tctttgatga
    25381 tggctggagg aaacgctgtt tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc
    25441 atgcgaaaga ggaagaaaaa ggacagatca tcacactagt caatctactg ggtactgtga
    25501 tgatgttgac tctccctttt cttggattac agttgtttgg tggaaatctc attgaaaaaa
    25561 gtgcactttt gggtggtaca ctccaatctg ttggtcaagt agtcgctggg gcaagcttac
    25621 ttgacaattc tgttgtcgaa ttcgccatgc tatttaagat tctacgtatt atgatgctcg
    25681 ttgttgttgt ctatctgttt gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa
    25741 cgccaactga tacgcagaaa aaacgaaaat taccgcttcc ttggtatgta ttagggtttg
    25801 tgatcttttg tttggtcaac agcttgtttt ctttacctgt agttattgac caatcggcac
    25861 attttatcag cagctggttt gagatcactg ctttagcggc aattggtctg cgtttagact
    25921 ttgcaaaatt catgaaagaa ggtacacgct tcttatctta tggattagct gtcgggcttc
    25981 tccaaacagt gatggcttta ctatttattt ggctgatcaa agtttagaat gaacatgaaa
    26041 aaacagttgt gattctcgca tggaacaatg tccgaatcac aactgttttt aattttgcag
    26101 atatccttct aacaacaaca attggcgttt gatttcaacc ccatctattg cgtttcccat
    26161 atatcctgtc agttttccat tttgcccgat cactcgatga caaggaataa cgattggcaa
    26221 tggattggtt cgatttgcct gcccaatcgc tcgcacagct ttcggactat caacagcaac
    26281 ggctacttct ttatacgttc ggatttctcc ataaggaatg gtcgacaaag ctttccagac
    26341 attttgctga aaaggcgtac ctctctttat agataaagga acatcaaatt cttttctttt
    26401 tcccgcaaaa tattcttcaa actgttcttg tgtgcgcgtt aaaattcgct gattcgctga
    26461 ttcgctttct gaaattggct gaaaagatac agcagtcaat ccggattcat ctgcatctaa
    26521 ccataaaaag ccgataggtg tgtgtatttt cattttgttt gctcctagtc aatagactgg
    26581 aacttcctcc tttttctcta tccaaaacta cttgccaact aataaaaaat gttcttaaaa
    26641 gtttgataaa ccgaggaaac atggtaaact aaatacgtta gtttacaaaa agaatacctg
    26701 ttcttttacg taaaatcaaa ttttaaaggt gttatttaag gtttattaaa ttttgaatgt
    26761 aaaccatata taaacatacg attgaaagga tagaaacgat gaaagtatca attgttgtcc
    26821 catgttttaa tgaagaaaaa actgttcctc ttttttttga tgaggttgaa aaattcaaag
    26881 gtgcccatga gttcgaatat ttgtttattg acgacggatc aaaagacggt acgttagcag
    26941 caatcaagaa gctagcctca gcttatcctt atgtccgctt tgtctcattt tccagaaatt
    27001 ttgggaaaga agcggctctg tacgctggat tgcaagcttc tacaggagat ttagtgaccg
    27061 tgatggatgt tgatctgcaa gatccgcccg aactgcttcc tgagatgatc aaccggatca
    27121 ctacttctga tatcgattgt gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga
    27181 tacgcagttt ctttgcgaaa aaattctacc agttgatcaa taaaatcagc gatacagaaa
    27241 tggtcgatgg cgctcgtgat ttccgcttga tgactcgtca aatggtggat gccgtcctag
    27301 aattaacaga atacaaccga ttttcaaaag gattatttag ctgggtcgga tttaaaacag
    27361 aatatatttc ttatgaaaac cgcgaacgtg tggctggcga aacatcttgg tccttctgga
    27421 aattattcaa ctactcgatt gatggtatcg tgaacttctc ggatgcaccg ttaacgattg
    27481 cttcatttat cggcgctttg tcttgtgtcg gttctggtat tgcaattttg ttcattattt
    27541 tgcgggcatt gttgtttggt gatcctacat caggatggcc ttccatggtc tcgatcttcc
    27601 tgttcattgg tggaatccaa ttgttatgtc ttggaatcat cgggaaatat attgggaaaa
    27661 tcttcttaga aacgaaacag cgtcctgttt atatcataag agaaacagaa aaagtgaagc
    27721 caaatgaatt gaagcctcac caataatata cgtcaaatga agtaaacatt tttttaaatg
    27781 aaaaaggact gtgacaaaag tcttgtcaca gtcctttttt ccgaataaat ggtgttccag
    27841 aagtagcttc ttcggaaata agccgaaatt tcacaaaaat ttgagaagca attttcgtaa
    27901 attccttctt atttcttgaa gctgaccact tctatcacaa cctctttcat atcttattac
    27961 ttcttcattg ctgcttttag tgctgctgct aatgggcttt cttctggttc ttctgcttgt
    28021 gcatattttt tcagcaagcg tcgttcttca tgtttggtca ttttcttctt ctgctctttt
    28081 ttatcaagca atttttctgt cgttccatcg tatttacaac ggaaataagc accgttttta
    28141 ccttcgatga tttccatttt ccggtgacat tgcgggcatc gatgattaga gacttttgga
    28201 tcttttcttc tgcggtagtt gcaatctgaa ttggtgcaga catagatttt gccgtcacgt
    28261 gtgtttttct cgcgcagatt ggccccacat tctgggcatt tcttttgggt aatcgagaaa
    28321 tcttgatatt cttgtttgct tgatttgatc tcattcacca agcgttttgt ttctttttcg
    28381 attccattca agaaggttcc tgcttgtttc tttcctgcag caatagcttc aaggtctttt
    28441 tcccagcttt ctgtcaaatc tggtgttact aaagagggat ttaccaatac taataattgc
    28501 ttacctttag gagatacttg cagtccttga ggggtacgtt ccatcagttc agatttgatt
    28561 agtttctcga taatctctgc acgcgtagct ggggttccca gactgtattt ttccatttga
    28621 ccaagcaagc ttgcttctga caatggttta ggcggtgcag atagttcttt tttgatggcg
    28681 aaatcgggat tgattctcat tcctttttcc catttgactg tttccgtctc agtttcagtt
    28741 tcgcctttcc atcctgcttg gacgacacga ttttgccgaa aaatgaatcg ttctttacca
    28801 aattcaaccg taacttttgt ttggctgact ttatggggtt gagcaaacag tcctaaaaaa
    28861 cgagagacaa tcatttgata gatttttcgc tcttcattac ttaatttttc ataacgtgct
    28921 ctgttttcag ttggcaaaag tgcatggtga tcggtcactt tactgtcttg gaatactttt
    28981 gtctgttgga cgatggctcc gtttttcaaa tactgcttga cctcaggagc aaagtcgctg
    29041 actgcttgca atcgttcttt catcgtactt ttcatgtcat ttgtcagata tttgctgtct
    29101 gtacgcggat aagtaacgat cttatgggtc tcatacaaac tttgtacaag acttaatgtt
    29161 ttctttgcag aatagccata gcgttgattg gcttctcttt ggatctctgt taaatcataa
    29221 ggcaatggcg cagattccgt ttttaatttt tcttggactt ctgtgacagt tcctttgctt
    29281 gtactgatca attgaacaag tttttgtgct tcttcttgtg tttttaaagc aaattgattt
    29341 ttttgaagca ttttggcttg ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt
    29401 ggacggaact gctcgatttt cttttcttgg tctctcacta atgctagtgt cggtgtctgc
    29461 acacggcctg ctgataaatt atccgcgtac ttcacagtta aggctctggt cacattcaat
    29521 cctaccagcc agtccgcttt tgcccgggca agagcagatt catacaatgc atcatattct
    29581 ttcgcaggtc ttagttgctt gaatccagtt ttgattgctt tatctgtttg agaagagatc
    29641 cataaccgct tcactggttt attgaaatgc acatactcta agatccagcg agcaacaagt
    29701 tccccttctc ttccggcatc tgtcgcaatg actgcttctg agacatcttt tcgctgagcc
    29761 agctgcttga ttgcttttaa ttgatgtcct gttttaggaa gtggtttgat tcctagtttt
    29821 ttagggatca ttggcaacgt gtccatttgc cagctctgcc attccttatt cagatcttcc
    29881 ggcattttca atcctaataa atgaccaagg gcccaagtaa cgatcacctt gggtccttca
    29941 taataatttt tgtgcttttg attagcacca agcaccttgc ttaggtcttt cgcaacgctt
    30001 ggtttttccg ctagaattag ttgtttcata aaattccttt ctgctttcta ctgtgatggg
    30061 ctgatgattt ttcaacaacg caagtccctt gtattgctgt aaatcatcgt cacactcttc
    30121 acaccagcgc tcatctccgt cattccaaaa ggcgctgaga aagttacttt ttgcattgat
    30181 atattcataa ttttgatgga tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc
    30241 gaaagactcg aatgtttctt cttcttcaat atcttcttcc cagtcttcaa aaaaccacca
    30301 aggctcattg tccccgaaca tggtaattac ttgatacata ctcgtgctcc ttctttcagc
    30361 ttttctagac tcatcttagt cacttttcaa gaaagttgca agaattttct cttataaaag
    30421 ggtcatttaa tgaacatctt aaaattgtta caaatgaatc tgattgttta aggcaaagta
    30481 gcgataaagt tattgatcat ccaaaaatag ctgtcttctg gatcgattgt tggttctttt
    30541 gtaaagtatc ctaaaaaacg taaggaaaga taaccgtgga tcatactacg aagttccctg
    30601 cttcgatgaa ctttttcttc tttcgttaat tgaaaagcct caaatatctg caaaatgatc
    30661 tgattcgttt catggattcc atctaataaa acagcttcat tggtatgcgg tacactgatc
    30721 agtaactcat acactgcttg atttgaaaaa gcaaaggatc gataagtttc tgcatagatc
    30781 tgcagtgctt cctgaccact ttttcccaca agagcccgtc gcagctggtc attaagttcc
    30841 tgcagaagtt tcgctgttag cgctgttttg acatcacgaa tatttttgaa atggttatac
    30901 agcgagggag ccttgatatc caagcgtttg gctaaatgct gaaaggttat ttgctgaaca
    30961 tccatctctt ctgctagttc tcgaaagcag tcgatgattt tctcttgaga cagatttctt
    31021 tttttcattt ccatgtttcc tctcataaaa taaatccttc actctttcag tttaccacga
    31081 aaaagaaaga gaaaaaagag actttcattg ataaactaca tattgtagtt tataataaag
    31141 agctgtagat gaaaattttc agaaagaagg agtctaattg gctgcaagaa taaaggaaaa
    31201 attatttagg aaaagagaaa cttgggaaca aaacttgttt gtcttatggt ttggaacatt
    31261 tatggctggt atcggattta gtttagtcat gccttttatg tcactttaca tagatacgtt
    31321 aggtaattat agtacgtcac aattgaactt ttggagcgga ttgacttttt catctacttt
    31381 cttggtgact acgcttatct ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa
    31441 attgatgctg ttgcgtgctt cattaggaat ggcaatcgtc atttctttga tgggttgcgt
    31501 gactagtgtg tatcaattag tcgcattgcg tctgcttcaa gggatttttt ctggttatat
    31561 cagtaatgcc actgcccttg tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct
    31621 tggaacctta gcaactggtt ctgttacagg aacattactt ggaccgcttc ttggcgggat
    31681 ctctgcttca gcgtttggct atcgccctac ctttttcatt acagggatca tcttattttt
    31741 cgtcttcttg ttgagtctgt ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa
    31801 catggtttct gccaaacaga ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat
    31861 gttcgtcaca acgatgatca tccaagcatc caacaattcc attagtccaa tcatcagtct
    31921 gtacattcgc caattgctgc atggacatgg gaatgttacg ttgatcagcg gaatcattgc
    31981 ttcgatacct gggattgcca ctttgatagc cgctccaaga tttggtcgct taggtgacaa
    32041 gattgggagt gaaagaatac ttgcgattgg tttgggtttt gcgattctgg tttatatccc
    32101 aatggcattc gtcacgaatg tttggcaatt agctgcctta cgttttttga ttggtatctc
    32161 tgatgcttgt ctgctccctg ctgtccaagc attgatcaca aaatattcgc ctcatcaagc
    32221 tgctggacgg atcttcagtt ataaccaatc tttccaagca actggtaacg tagtagggcc
    32281 tatgatcggc tccagtgttt ccagtgcatt tggttatcgt ggcgtctttc tttcgacttc
    32341 tcttcttgtt ttggtcaact tcttgcttgt acgacacaat acacaagaga tccatcagca
    32401 agaaactgca gaagaaaaag cttcaggagt ctccatagct tcagggcact ctccttctca
    32461 tagacaataa gcgtaaatga aaaacactgc ttgaacagtt gtcacagact gtccttgcag
    32521 tgtttttgtt taggcctgtt ttttcaagaa ctcagataag aggaataatc ccttttccaa
    32581 ggtttctttt ttacaacagt aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc
    32641 tggtactaat agtactcctg tttcttctaa taaattgata caaaatgtct ggtcatcttc
    32701 ttcgatggct aatttaatga aagaagtaga gacgtaattg ggagcgacaa gttcaacttt
    32761 cggttcattg gctacccatt gttttaaaat cacaaggttc tctgtaatga tctttttgtt
    32821 tcgcgccaat attttttctt tattcttcaa tgcatgtaca gcaagatcat ctgacaggac
    32881 tccgccgcaa atcatcgtgt agtctcgata ctttcgaaaa acttctgcca actcaggtcc
    32941 agtagctgtc cagccaatac gaatacctgg aatggagtag gttttggata gggaattggt
    33001 tgctatacct ttttcataga catctacgat cgacaagaat tcacctttat ccgttaaagg
    33061 cgcatatact tcatctatca atacatatgc atctactgta cgagcaattt ctgcgatttt
    33121 ttctaaagtt ttccgatcta gcaatgtgcc tgtaggattg tttgcactat tcaaacagat
    33181 gatttttgtt tcaggtttga ctaaggcttc tagctgttct aaatcaaact gccaatcttc
    33241 ttcttccttc aaatgaacaa agtcaacagc ggcacctaaa gatttgggga tgtcatataa
    33301 ttgctgataa gtaggaagca tcgaaacaac atggtctcct gcttccacta acgcgtatag
    33361 agctaaaaga ttagcaccag tcgctccatt cgtttgtaag atgttttccg gatcgacggt
    33421 ttgataaaga gaagcgactt cttgtttgaa aacatctgat ccttcgatcc agccatagtc
    33481 caatggttcg tttttgcgtt tttcgaaaaa tttacttacg ctagtcccat ctaagccaac
    33541 gagttcgtct aatgtcaatg cttcgatcga gctttgtgca atatcatata ccgctttctt
    33601 ttcccattta tttagccatt cttctacacc gaaatttgcg attttcatgt ttctttcccc
    33661 cttatatctt gatccagcct acagcaagca acccgattga aagcagtgcg gccacacaaa
    33721 tcagcccaat cattactttt tcttttcccg taatttgatg tttggtttca cgacaagcga
    33781 tccagtagaa gcaaaaacca ggaagatagg caatactaca taaaaggaca taagaaaatc
    33841 ctgctaaaat gatgcccatc aattcaaaaa ctacagcaat cccaccgatc actacttgtt
    33901 ttttgattcc ttcttttaaa gaaaactgga cttgatagat cccgacaagt agataacaaa
    33961 tcaaaattgc cgctgtacat aaagaatagg caaattgata ggcataatca gtaactaaga
    34021 aagtcaataa gaatagatta gtcaagattg cagtaacaac taacgaataa gttggggcat
    34081 tttttttatt cgtttttccc caacctttcg gcaacagacc gtctcgagcc atcaacatcg
    34141 ttgtttctgc tgggagcatc gtccaagaca accaagaacc aatgatcgaa ataatcaagc
    34201 cgatattgat cagcgctgct ccccaatttc ccacgattcc ttttaaaata tttgccatag
    34261 caggttgtga aatagttgct aactcttctt gagataagac gccgtatggc aagatcgaag
    34321 caaggatata gataaacaat aaacaaagca gaccaatgat cgatgcttgc tgggcttctg
    34381 aacgtttctt cgcgcggttg gctaaaacac ttgcgccttc gatccctaca aagacccaca
    34441 tcataaccat caaacaacct ttaatctgca accagatcgt tccttgctgc cctgttccat
    34501 tcactagatt atcagatacg ttaccccaaa aatcagcagt gaatatattc actttaaatg
    34561 cgataaatac aaatattaaa aataggaata atggcactaa tttacagatc gtcacgattg
    34621 tattgatgac gctcgctcct tcaactccat tgtttactaa taaagtcaga ccccaaataa
    34681 aaatacttgc aaataaaata gaaggaacat tttgtccacc tttgaatatc gggaaaaatt
    34741 ctcccatggc gctcatcagc atcgttgcaa aagcaacatt tcccagccac gcagacaacc
    34801 agtaacccca accactgatg aagccaccta atttaccaaa tgaagcttcc gcgtaaccga
    34861 aaataccacc atctagatct ggacgctttt ctcctaaatg attcagcgat aataccaaag
    34921 ctaaaatacc aatcccaacg attatccatg aaaggatcgc tggccctgga gctgcagaac
    34981 tagccagatc acttgtgatc ccaaacacac cgcttccgat tgacgaactg acaaccagag
    35041 caaccagtcc ccatttgcta atacccgtcg atttcttttc catttccatc accctcactt
    35101 ataaaattga acaaatcact tgcaaaagat tcccttctat tttgcaactg ctcttgctta
    35161 acaaaaagca actttattca tattattgga tattatgaac tttttacaca agtatttcaa
    35221 gtataaaatg aataaaaatt aattttattg caaaaaaaca gctatgctat ccaaaagaaa
    35281 aggtgtttct tttgttagcc atagctgttt tgattcattt aatatcgctt aaacgtattg
    35341 taaaactttt gtttcttgat atgcgtggtc gatcaaacca ccacccagac attccattcc
    35401 atcataaaat acaactgctt gtccaggagt gattgcacgt acaggttcgt cgaatacgac
    35461 ttctgcacga ttatcatcca ataagcgaac tgtcacagga acgtcttgct gacgataacg
    35521 gaatttcgct gtacacttga attcttttgg cattggttca ttcgtcgtaa agtggatttc
    35581 acttgcatcc aagcttgtgg catacaatgc aggatgatgg aacccttgcc ccacatataa
    35641 tgtgtttgtc gctagatctt ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc
    35701 accgatccct agtccttgac gttgaccaat cgtataatac atcaagccag catgttgtcc
    35761 tttgacttca ccatcaagag tgaccatatt tccttttttt gctggcagat agttgctcaa
    35821 aaattgtttg aagttctttt caccaataaa gcagattccc gttgaatctt ttttcttagc
    35881 agtcgcaagg cctgcgcgtt cagcaattgc ccgtacttct gatttttcca tgccgcctag
    35941 agggaacatc gtttttgaaa gctgttcttg tgataattgg ctaaggaagt aagtttgatc
    36001 tttattattg tctactccac gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg
    36061 cgcataatgt ccagtagcta cataatcggc gccaagatcc attgcataat ccaagaatgc
    36121 tttgaatttg atttctttgt tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta
    36181 ttcggctagg aaatattcaa atacacgatc ccaatattct ttttcaaaat tcacagagta
    36241 ataaggaatc ccgatttgag cagctacttt cgctacatcc ttataatctt ccgtggccgt
    36301 gcatacaccg ttttcgtccg tgtcatccca atttttcatg aatattccga tcacgtcgta
    36361 tccttgttcc tttaacaaaa gtgctgttac agatgagtcg acaccgccgc tcatccctac
    36421 gacaacgcgt gttttgctgt tgtctgtcat gatatcacca tcatttcaat tagattctga
    36481 aacatctacg agttgaaggt cgcaactttt cagtatttta cattatacgt catatttctg
    36541 aaaatttcat cccttaatta tcaagtcgta aaaatactgt tctactggac ctattcagta
    36601 cacaaacatg atagtcaacc aaaaaatcac tcatcttttg agcattcgat ataaaaaatt
    36661 ggcatactca taaaaagggc cagcctttcg gcaataagga ataattttat aaattgtgaa
    36721 aaactatttt tcaaaattgc ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt
    36781 tctttttaga tgttatgagt tgctcagata agtgattttg tttactctaa gaaaaaaggg
    36841 aggcaaaaga tacatgaatt actttatcag tgatatgcac tttttccatg aacgcttatt
    36901 aggaaaaaac gactttgctc cgcggctctt tgcaaatgtg gatgaaatga accaacagtt
    36961 gatcactagc tggaatgcag taataaaaga aaccgaccat gtttatcatc taggcgacct
    37021 tgctatgcat ccgcaatatg aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact
    37081 gcaaggaaca atccacttga tcaaagggaa ccatgacagt cgcgcttttt tccgttattt
    37141 agaaaaaaat gatcctaggc ttactgacgg aagtcccaaa ttttattttt atgatgtagg
    37201 tgccatcgtt aaattcgacc atcaacaata ttacttgact cattatccga tgttgctcgg
    37261 gcctaacgac actatccgca atcttcatgg acatatccat cattacagcg tacctatcga
    37321 gaacgatgtc aatgtaggcg tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc
    37381 atttggcact ccgttatctg agcaacaaat caaagaaatc tatgaagcaa agaggaagta
    37441 cgataggtcg tgaaaaaact gccctatatc aagtattaaa caaataaaga taattactca
    37501 tatttttcat ttgagtaggc ttattgccac aggaacatta ggatcagaaa tggagttgta
    37561 acaagacttc tgtcacaact ccattccata ctattcgtct ttttgctcat ggtgttcttt
    37621 taccagtttt ttctgtaatt ctttatcata atttcgggca gctgacgtta aaaataaaac
    37681 gattccgcat aataaaatcc cgattccgga aaacaagaac attttttcta cccctaaacg
    37741 atcagctaat ggtcctgcaa ataataatcc aattggacct gtcaggttca tcaaagagtt
    37801 gaagttccct aagacacgac ctaaaacatt cgattcataa ctctgctgga tcattgccat
    37861 cagcagtgta ttgaaatatg gcgttgcaca acctgctcct gcattcaaga taagaaagta
    37921 caagaaccct tgactatcgt ttggaaccaa tccgcttgca ccgatcgtca ggcccataat
    37981 gatgtaggct ataataatag gtttcattcg gtctttccat gttcctataa aactgatcag
    38041 tgcaccgcct aagagcattc cgactgcgta gactacttcc actgctcccg cctgtccaac
    38101 ggaaccacca aagtaatcta gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa
    38161 cagcatcaca aatgcaccat tgatcgttat gtaccataac cctttattat ccatcaattg
    38221 ctgcagccca aattttgcat ctttaaaaat agtaagcgga acttccaata tttcaggaga
    38281 aacttttggg atcttcacaa aaatcaataa gccgacacca aaaactgccc ccaatacatc
    38341 taataaaata aggtaattga caggaacgac tgaaaacaaa gccgcaccta gagctggcgc
    38401 aatgatgaaa ttcgctgatt ggaccattcc taactgtcca ttcgtccttg ttatgtgaga
    38461 agatggaacg attgtcggca taatcgactg gatcgttggc atttggaatg tttgtgcgac
    38521 cgaacgcata aacaaagaca caaaaactag ccaaatcggg aaggattctg aaatcgttcc
    38581 gactactgct aaaataagcg cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc
    38641 ttttttatcc cagcgatcca ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat
    38701 cattcctagt aaagtagcaa aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata
    38761 ccagatgatc gcatattgga cgaccatact agtgattcct gacaaaaact gtcccgataa
    38821 aaagaacaaa taatttctct tccaattcgt taaaacgacc gactgttcat tttccataaa
    38881 catccctctt ttctttttca ttttgtatag cgtttgcaca acaatcatta tacgggattc
    38941 ttttttcaaa aaataccttt ttccctaaat aacaatcgtt tcaatttaaa tttctttact
    39001 tagaaacaat aaatcagcaa aatattaaaa ataacaacat gtgttaaatt taaaaataaa
    39061 aaagacaact aatttgcgtc gtccttacaa agttagtcat ctaacaatag gccgtttcaa
    39121 aactagttgt ctttttatat ccacagatca ttcgactttt tcgaataacc cacggctaat
    39181 catcccatcc atcagaaaat aaaatttatc ttggctcatt ttctgttttg gatctttgaa
    39241 aatattgact gctttcaatc catttgctgt agtgatcgac attttcaatg tttgaatatc
    39301 ttttgataca gtgattttta atttgaatcc ttctttgctt tgcggcgtgg catctaatgg
    39361 tcggatcaat tgataattgc ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata
    39421 tctttttgca tcaggatgca aacgatagct aattggtgcg cccagtaccg ttgctgttgt
    39481 ttcaaatgcc atgattttca cctcgataaa attagtttct ctttattata aaagtttatc
    39541 ctgattttta ctaggttttt cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca
    39601 tctgttcata taagaatgac ttcactagtt attttttgac agcacgaact aattgatcaa
    39661 ggaaatactg gatgtcgtct tcggtatttc ccaaaccaaa gctgatacgg atggattctt
    39721 ttagtatcgg tgtatcttct ccatacattg cttccaatac gtgtgaaggc tcgatatttc
    39781 ctgctgtaca agctgaacca gtagaaatag cgaccccatt aagatcaagc ttcatcagta
    39841 gcaaatcatt tgcttcgcca attaagcgaa gattcaacac atgagggagt ttattcgtta
    39901 aatcaccatt tacttgataa gggatttcgt ttgcttctaa tgtatcaaga atcaattgct
    39961 ggaatccttt atatttgttg ttacgtgctt cacgttcttc aggtgacagc agttcaactg
    40021 cttttgccat accccagatc cctgctaaat tttctgtacc tgcacgccgc ttttcttcct
    40081 gctccccgcc taaaagcaat gcagggatat ttactccgtc tcgtttatat aagaaaccga
    40141 cgccttttgg cccattgatt ttatgagcag agatacttaa taaatcgatt cctaattctt
    40201 ctggatggat cgtttggttt ccgtacgctt gtaccgcatc tgtatggaaa taagctggat
    40261 gatccgctaa aagttcaccg atttctttga ttggcatcaa atttccgatt tcattgttcc
    40321 cgtacatcac agagaccaag atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg
    40381 acagattccc tttttcatct acaggcagat atgtaacgtc aaaccccttt gtctctaaat
    40441 atttcatggt attaagaaca gcaggatgtt cgatagctgt agtgattaga tgtctgcctt
    40501 ctttttgacg cgagaacgct gtttctaaga tagctgtatt atccccttct gttcccccac
    40561 tgttaaagat gatctcgtga ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg
    40621 tttccaattt ttcatgcgcg tggcgaccaa atccatgtat gcttgaagga tttccaaacg
    40681 tgtcttgcat gattgccgtc atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg
    40741 catgatccag ataaatagtt ttcacttcat tcatcccttc caaattattg ctaggcacat
    40801 tctagcataa aatagcgaac aaaccaaaga agagctcatt tttgtctaga ggacgtttca
    40861 tgggcataga aaaaaggagc tgtgacaaaa gtcttgtcgc agctccttga agctgctcac
    40921 ttctgtcaca acttctt
//
LOCUS       DARBDN010000016        37010 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000016 DARBDN010000000
VERSION     DARBDN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.016"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..604
                     /locus_tag="SCH06_000872"
     CDS             <1..604
                     /locus_tag="SCH06_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1077470.1"
                     /translation="GADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTA
                     VVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAID
                     GLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPT
                     SSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1028..1198)
                     /locus_tag="SCH06_000873"
     CDS             complement(1028..1198)
                     /locus_tag="SCH06_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1077471.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1392..1571)
                     /locus_tag="SCH06_000874"
     CDS             complement(1392..1571)
                     /locus_tag="SCH06_000874"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077472.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            1958..3070
                     /locus_tag="SCH06_000875"
     CDS             1958..3070
                     /locus_tag="SCH06_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEG1077473.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3148..3441)
                     /locus_tag="SCH06_000876"
     CDS             complement(3148..3441)
                     /locus_tag="SCH06_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEG1077474.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3609..3923
                     /locus_tag="SCH06_000877"
     CDS             3609..3923
                     /locus_tag="SCH06_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEG1077475.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3944..5923
                     /locus_tag="SCH06_000878"
     CDS             3944..5923
                     /locus_tag="SCH06_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEG1077476.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5936..6262
                     /locus_tag="SCH06_000879"
     CDS             5936..6262
                     /locus_tag="SCH06_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEG1077477.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6278..6796
                     /locus_tag="SCH06_000880"
     CDS             6278..6796
                     /locus_tag="SCH06_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077478.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6796..8148
                     /gene="celB"
                     /locus_tag="SCH06_000881"
     CDS             6796..8148
                     /gene="celB"
                     /locus_tag="SCH06_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEG1077479.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8232..9737)
                     /locus_tag="SCH06_000882"
     CDS             complement(8232..9737)
                     /locus_tag="SCH06_000882"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEG1077480.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9829..10419)
                     /locus_tag="SCH06_000883"
     CDS             complement(9829..10419)
                     /locus_tag="SCH06_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1077481.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10598..12244
                     /locus_tag="SCH06_000884"
     CDS             10598..12244
                     /locus_tag="SCH06_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEG1077482.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12293..13012
                     /locus_tag="SCH06_000885"
     CDS             12293..13012
                     /locus_tag="SCH06_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEG1077483.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13491..14438
                     /locus_tag="SCH06_000886"
     CDS             13491..14438
                     /locus_tag="SCH06_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1077484.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14450..15370
                     /locus_tag="SCH06_000887"
     CDS             14450..15370
                     /locus_tag="SCH06_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1077485.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15411..16868
                     /locus_tag="SCH06_000888"
     CDS             15411..16868
                     /locus_tag="SCH06_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1077486.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17213..17827
                     /locus_tag="SCH06_000889"
     CDS             17213..17827
                     /locus_tag="SCH06_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEG1077487.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17820..19544
                     /locus_tag="SCH06_000890"
     CDS             17820..19544
                     /locus_tag="SCH06_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1077488.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELRELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19541..20992
                     /locus_tag="SCH06_000891"
     CDS             19541..20992
                     /locus_tag="SCH06_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1077489.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21465..23618)
                     /locus_tag="SCH06_000892"
     CDS             complement(21465..23618)
                     /locus_tag="SCH06_000892"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEG1077490.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23620..24666)
                     /locus_tag="SCH06_000893"
     CDS             complement(23620..24666)
                     /locus_tag="SCH06_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077491.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24816..26105
                     /locus_tag="SCH06_000894"
     CDS             24816..26105
                     /locus_tag="SCH06_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEG1077492.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26118..28820
                     /locus_tag="SCH06_000895"
     CDS             26118..28820
                     /locus_tag="SCH06_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEG1077493.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28805..29662
                     /locus_tag="SCH06_000896"
     CDS             28805..29662
                     /locus_tag="SCH06_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1077494.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29733..30632)
                     /locus_tag="SCH06_000897"
     CDS             complement(29733..30632)
                     /locus_tag="SCH06_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEG1077495.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            30801..32972
                     /locus_tag="SCH06_000898"
     CDS             30801..32972
                     /locus_tag="SCH06_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEG1077496.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33040..33381
                     /locus_tag="SCH06_000899"
     CDS             33040..33381
                     /locus_tag="SCH06_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEG1077497.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33657..35411)
                     /locus_tag="SCH06_000900"
     CDS             complement(33657..35411)
                     /locus_tag="SCH06_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077498.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35422..36258)
                     /locus_tag="SCH06_000901"
     CDS             complement(35422..36258)
                     /locus_tag="SCH06_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEG1077499.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36260..36943)
                     /locus_tag="SCH06_000902"
     CDS             complement(36260..36943)
                     /locus_tag="SCH06_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HEG1077500.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11942 a         6503 c         7573 g        10992 t
ORIGIN      
        1 aggagcagat ggaaaactgg cgattgacgg cttagcacca ggagtgtatc agctggtaga
       61 aacccaagcg ccaacggggt atgaattgga tgcgacacca atcgagtttg agatcgaaag
      121 aagtcagaca gcggtggtag aattgacgaa agaaaatcga cttacaccag gcggtgtcgt
      181 gttgacaaag atcgatgacc aaagcggaga agtcctgcaa ggagctgttt ttgagttaca
      241 agatgccaat ggaaccgttc tgcagtcagg tctaaccaca ggagcagatg gaaaactggc
      301 gatagatggc ttagcaccag gagcatatca gctggtagaa actcaagcgc caacggggta
      361 tgaattggat gcgacaccag taactttcaa gatcgaaaaa gaacaagaag tggcgatctt
      421 tttaacaaaa gagaatagaa aagttgctga tagctcagat ataagaggaa acaatccaac
      481 aagcagtgga aataagcatc ttccaaaaac tggagaaacc atcattagcc agtttatatt
      541 gtcaatattg ggtgtgctac ttgttttcat cagtataaaa tttagaaaga aacgaaatat
      601 atgagctaaa ataaaaaatt gaataagcat agtttttaaa atcaactagt acccatcaat
      661 tgaatggaaa ctaccgattt tagaaggggt atacaaacaa atattagtat cggagtagag
      721 aaggttgaac ccaaccagta aataagtaaa gacaattttg tgctgcgttg agaagtgaaa
      781 aataaacctt tgtagtaata ctagttaata aaaaatatac aaaaacactg cgaaaatcat
      841 tcttgagttt cgcagtgttt tttgcctaat gactcaagtt tattgggtaa tactttgatt
      901 ttctttctac aaataatcag cgatcagttg taattttttc tctagtttta atggctcttt
      961 gtcaataagg agaaaaacaa gtcgggtctt ttgtctcgga aagcttcaac caactcgtga
     1021 ataaaggtta cgcctccttg aaaggcgtgg aaaaaccaag taatcgatca atcaccaatt
     1081 tcgcatttgg tagaacatgt ttggtgagct gaaagtaggt ggcgttcatg tctgtaacta
     1141 agaattctat ttctttagga ttagtgcagc taaggaaata gtttgttaat cgaggaattt
     1201 tttgtgtagg taaattttct cgattaattt ttctgtctcg ccatccgcgg aaataaaact
     1261 cagtttatcc tcaacggaaa cgtgagaacg aaattcacaa ccctcaacac tcaagacaga
     1321 attcttttgg aagactttgg taaatagctt ctcaactctt tcaatgtgcg aataacggtt
     1381 gtcaaagata cctaacaact tttcgaaata aaaaataacg acactttttc agtcagtaaa
     1441 gaagtgattt tatgtctgac atgatttgaa atcgagtgcc ttggacggat aaaataactt
     1501 tgagcgttcc aatggcttcg acagttttta caggtatagc gctgcttttt taggcgtata
     1561 accattggca tatgattata ttattcaaag tggacaatgg tttccttctt cttgtttttc
     1621 accaccatta atttcctatt tccatctacc acagcagaac cacaatttct acagacacat
     1681 ggagcaggga agagaactgc agcaacgatc aatgtttttt tcttctgtaa ggtttcgtaa
     1741 gagacctctg taatcatcaa atttttgtct attgatctca gaattttttt gatagaacca
     1801 ttcataaagc atatcgttct ctcagttgtt tattttgtgg tgatttaatc atacaagaaa
     1861 acgatatgtt tttttataaa aacatgaata ggaaaaatag ttgacaagaa aatgacaacg
     1921 ccatatgatg ttccatagta tttacaacct gtcatagatg actgtaaaaa ataaaagtaa
     1981 aaagaaagga cgacaacagg tggattttta tcagtctcta caactagatc cgtttatttt
     2041 aaaacaaaaa atacgagaag cagcttctaa aaaagaaaag tgcatgtata tttgttcatt
     2101 gtttttacga tcattattca tcgtattgtt tgccatttgt tttatcatta taattacaac
     2161 attatttgaa tcgaagcata aaccatacgc tgtggtttta ttctgtatgt tgatgagtat
     2221 tcgttttgtt gactttggtt ataagatttc ccattcgatc ataggtttag caatcgtcat
     2281 gttctcacta ttagtagcac cgtatgtcca gctgatcaaa tggtcagtta tgggcatgtt
     2341 gattcatttt attttactaa gcagcatatt aatggcaacc gctagtgatc ccaaaatggg
     2401 gaatgcttct ttgtacggct tttcatatct ctttattgtt tattcgttac ctaaagattc
     2461 gttgaacaag aatttcttta cacaaacaag tagcttatta tttttgtttt tttgttggtt
     2521 ttcagttctc ctttacagaa aacatcgaga aaagaacaaa gacaaaagct tgtttaaaga
     2581 gatttttttg aaaggcatgt attcgcagga aaaaatttgg atgctcatct atgcatttgg
     2641 cattagtctt ttgatcgttg caggagagta tgtccctttt cagcgattga tgtgggcagg
     2701 gtttgcattt tcttctattg tatctagcta tggattgatg tcgattggtt tcaaagaacg
     2761 agcagtagac cgaatcattg gctcattgat tggatgtgtt ttatttattg gtatcagcca
     2821 atttattcct tttaactggg tcggtatatt aggtggtcta gctttaggtg tttgttctac
     2881 ctatagatat aaaacagttt ttaattcttt tggtgctttg gcaatcactg ccagtttatt
     2941 cggggttcca ggagcagtaa cgatccgcat ttttgagaat atccttgggg tatgtttagg
     3001 aatcatgtat attggggtga ctgaaatact tatccgaaaa ataagagaaa aacacggttt
     3061 gaatcattag atgagatcga ataaaaaata aggaaaaagt gaagatacac atggatgata
     3121 aattgctatc attccatgtg tatcttttta cggtaaatca gtgaaacgtt cgactttcat
     3181 ttttaattta tactttttac ggagttcgtt tatttgagcc atcatttcgg atttgtgatg
     3241 cttttcgatt gcttcttcat ctttccaacg gtcgatcagt aaaagagatt ctggatcttc
     3301 tagtggaaag taatagtcat atttctcgtt tccttcttct gcacgaatcg ctttgacaat
     3361 gtttctttcg accatttctt ctgcaaattt tctggcttgt ccatttgtac ttgtatacaa
     3421 aatattcact gtgatactca ctaaatcccc tcctgaaaaa attctatcac tagtatatca
     3481 cggtgccaga aattattatt caagatatga tacacatttt ttccgcaatg ctacggaaat
     3541 atatattttg aatagaaaac gcttacaaga tatgcttggt ttataaaaat aaaaggagtg
     3601 attgatttat gaaaaaagca ttgattattt gtgcggcagg aatgtcatcc tcgatgatgg
     3661 cctcaaagac aacggatttc tttaagcaaa aaagagaaga ggtactcgta gatgcagttt
     3721 cagctacaga aggcgataat atgattaaga atagtgattt tgatttattt ctgatcagcc
     3781 cgcaaacgac gatgtttttg gataaattca aaaaattagg agaatctgtt ggaaagcctg
     3841 ttgttagtat ccctttccaa gcgtatgtcc caatccctac aggcatccag aagttagcag
     3901 aggtgatcga agagaacata tgatggaata ggagtggatg ataatgaaac agaaggaaaa
     3961 attgctgttg agatatttga ttgatcacaa gaaggagtat gtcaccagtc aacgtttagc
     4021 ttctgaattg ttattatctg atcggacaat ccgtaattac ttgcagcgga tcaaagagtt
     4081 agtagaaaaa aacggaggta agatcattgc taaaccaggt tatggctacc aactgcatat
     4141 tttacaaaga ctgacatttg acttgttttt gagtcggcaa gaaatagtac ctggatatgc
     4201 tagagaaccg caaggatttt atgagtccga agatcgacaa aagtatatat tgaaccaatt
     4261 gcttttggaa gatgccattc tttttatgga tgatttggca gaagagcttt atatcagtcg
     4321 ttccagtttg acaaaggaca tgcaagaaat caaggagcga ttgattccat attcactaaa
     4381 aatcgtttct aagcatggtc aagggacatg gatcgaaggg gaagaaagaa atcgacggca
     4441 ttttatcatg gatacttttt ttggaaacca ttatggaaat tcattgaaag aatatttagg
     4501 gcaaagccgt tttttcccag acatcagttt tgaagagcta gtcattatca ttctcgatga
     4561 aacaagagaa gctaagttaa aagtttcgga ttttatcata cagaatctga ctttacactt
     4621 ggctttgggg atcaaacggc tccgagaagg gtttgaaatc aaggaattag gcatcgaaca
     4681 agaagtttct aagcgagtag agtatcaagt ggcgcagcgg atcgttcaac gtattgaggt
     4741 aatcgcaggt gtatcgtttc ccgaagaaga aattgcttat ttgacattac atctcatggc
     4801 taagtcgaat cacaaagaaa atcaaaatga tcaggaacta tcaaaggaat tagcgaaagt
     4861 tctgaaaaga ttgtctcagg aatttcattt ttcattagta gaggatctcc agcttttcaa
     4921 tggactactc gatcatttgt caccgatgat gattcgattg agccgaggta ttcgcattga
     4981 gaacccattg actgaggaga taaagaaaga aaatcccaaa gtctttgacg cagtaaaaag
     5041 gcatttcagc aacatgccgg ctttgaaaaa ctataccatc aatgaagatg aatgggccta
     5101 tttggctttg catctcatgg cggcattgga aaaagaaaga gctgcgcata aactacatgc
     5161 attgattatc tgtgcaacgg gttacggcag tgcccaacta ttaaagaatc gcgtagtcag
     5221 tgaattcggt aaaaatatta cagtggtaag tgtaaaaggc tattatgaga tcaatgaaac
     5281 aactttaaaa ggaatcgacc tgattatttc ttctattgat ctttcgacaa tgtttttcaa
     5341 aattccagtt ttacatgtca gtattttttt gaatgaagat gatgttcgta aaatacgaaa
     5401 ggtagttgga gaatctatac cctatcattc ctcagataga ccgataccag cattttctct
     5461 acagcaaaaa aagcagattt acaccgaaca gttgtctgaa aaatttttca agacttatac
     5521 gtacgaaccg aaaaaggaag aaattcttca tgatttgctg caaaagctga gcataaatga
     5581 agaagaagga tatataagag aaatgcgaaa gcagatccag caacgtgaaa atatgggaca
     5641 aatcatattc agtgatacag tggcagtccc acatcccgct gttccagttg gaatcgaaac
     5701 aaaggtagcc gttgcattga ttccttctgg gatgcagtgg gatcaatatc aagaaattca
     5761 ttttgttttt ttagtttcgc cttcttatgt cgaaaatgaa ggaattacgg tcgtgactaa
     5821 agcaatcgtt aggttagttg accagctaaa agtacagcag gaaatcttag ctgaacctat
     5881 ttttgagaat ttcagcagta aatttatcaa actgatcgaa taaggaggaa aacagatggc
     5941 tgaaaaaata aacagtgaaa cactacaagt gacttctttt gatatcattt tccatagcgg
     6001 aaatgcacgg acactgatac atgaagcatt tcgctcgatg cgtaaagaga tgtttgaaga
     6061 agtagaagag aagttgcgac aagcaaatga agagattctt catgcgcatc agtcacaaac
     6121 tcaacttctg aaagaatatg ccagcgggac aaaaatagaa atggaaatta tcatggtcca
     6181 tgcacaagat catctgatga cgacgatgac attattggaa gttgcacagg aaatgaatta
     6241 tttgtatcaa aaaaataaat agaaaggaag gatcattgtg caggatacag taaaaaggaa
     6301 aatcgaatta gaaaaaaagc aacttagttt gaaaaacatg tatttcaatc gttatctaat
     6361 cgtacgttac ctgactgcct ttttcttttt catgaacatg caatggatga ttctgcttct
     6421 atcagctaaa agtttaggaa gtagtttacc gatgattctg attttagcta ttttgcctgc
     6481 agtaggagaa caagtaaagc tttatcgaaa acaccaaacg aacgttccat ggacaaagtg
     6541 gtattttttg ttccagagtg tctttaattt attagtgatt ccagtgttgt ttacctcagg
     6601 atttacattc ttgtatcctt ttatggcaaa taacaatgga ggacagttat ttgttttcat
     6661 tcttgttgta agcggtattt ttgccagtgc atttatacag tatcgtttaa agaaaatttc
     6721 actcaaccaa gaccaacagt atatccgtat taaacaatat gaaaaagcgt tatatttagg
     6781 aaaggagaat aactaatgtt tgattttttg cagaaatacc tgatgggacc tatggggaaa
     6841 attgcgcaac ttaaaatcgt tcgggctgtc atggcagcgg ggatggcttc tattcctttc
     6901 acgattgtag gctcgatgtt tttggtttta aatattttgc cattaccgtt cccattttta
     6961 gaaggatttt ttaatgcaac ttttttcaaa gttagtgact tgtacatgat cgtcaataca
     7021 atgacgatgg ggattttatc tatttacttt gccattgtgt ttgcttatga attaacgtca
     7081 attgaacgag atgaacaaaa attaaatgtt aatccgctca cgggggcatt actatctgtt
     7141 tttgcattct ttatgtgtat ccctgaattg atcatgactg atggtaaaat cagcttgatt
     7201 gcttctatca atgagacaga aactgtagta aatggtatta ggatgggctc ttttgtcgaa
     7261 cgtttaggaa cttcaggaat ctttacagct attattatgt cgattattgc ggtcgaattg
     7321 tattgtatgt gtgtcaagag aaattgggtc ataaaaatgc cagatgttgt tccgccagga
     7381 gtttctcgtt ctttcactgc tctgatccca acatttgtca ttgcgtttgt ggtgatgatc
     7441 atcaatggat tattagttgc actaggaacg gatatcttca aaatgattgc tatcccattt
     7501 gggtttgtta cgcagttgac gaatacatgg cttggtgtca tggtgattta tttcttgatc
     7561 catgcattgt ggatcgtagg gatccatgga gcgaatatca tcacttcttt cttgaccccg
     7621 atcgtattag ctaatatggc agctaacgca caaggcgcaa attatccgtt ggcaggagaa
     7681 ttcaacaatt cttatgtaac cgttggtgga tcaggtgcga ctttaggatt gatcatcttt
     7741 attgcattcc tcgcgaaatc tgatcagctg aaagtgttag gaaaagcctc acttgtacca
     7801 ggattattca atatcaatga accaatcatt ttcgggatgc caatcgtcta caatccctat
     7861 ttagcggttc cgtttttctt agctccgatg gcttctgcta cactcgctta ttttgccatt
     7921 cggctggaaa tcgtcaaacc gatgcttgca cagatgccgt ggccttcacc agtcgggatc
     7981 ggagcatttg ttggtagtgg tggtgattgg aaagctgctg tgttagcagt catttgtgca
     8041 atcatcgcat tcattatctg gttcccattt atcaaattct atgataataa attattaaat
     8101 gaagaaagag aaaaggcagc agaattagct agtgaaaagt taaaatgatt tctaagaaaa
     8161 aaggaactgt gacaaaaaat cacagtccct ttttttctta gaaatgggaa accactagta
     8221 tataaatacc attattcttc aatcaaccgc ttcacgattg cataatcccc ttcataaggt
     8281 tcatctacac cattgatttt ttgataggga tccacgcctt ttcccgcaat aacgactgaa
     8341 tcttgcggag cgctttctgc taaagcgcgt cgaatcgctt caggacgatc catttcataa
     8401 tgaacgatca aatctggatt agtaattgct tcattgattt cttccgcgat ttttttcgga
     8461 tcttcaaatg ctgggtcatc tgccgtcaaa aaggcgatgt cagctgtttc tgatagcact
     8521 tttccaaaat catgtcgacg ggagattgct ttgtttcctg ggctgcctaa tacaacaatt
     8581 acacggccat ctggatgttc atttttggca aatttcagca atgttttcaa gcttagataa
     8641 ttatgtgcat agtccacata gacatgcgct ccattggatt ggatcaattg atccattcgg
     8701 cctggtacac gagcttcttt taatccgtct tgtgcatctt gactggaggc acctgttagt
     8761 gctgcggcaa tgatcgcact ggctgcattt tcttggttga atcctccagc cagcaaaata
     8821 tcataagcag tatcgcagat agctaagcga tcttcatgag aagataaagt aaaaccgtga
     8881 gtacctttat ctgaacggat cacttgataa ttgctttctt ccgaacgacc ataagtgatc
     8941 gttggaatct ggaatagatc ggctgtttcc ctaagtaaat caaaatagtc actttcatga
     9001 tttaaaacaa ctgtttttga attcaagatc aattgtcgct tgcaatagaa atagtcatca
     9061 aatgtcggat gttcgatcgg actgatatgg tcaggcgaga tattcaagaa gattccgaca
     9121 tctaaagtca agccgtatac gcgttgtgtt ttgtaagctt gtgaagaaac ttccatcact
     9181 agatgagtca taccattttc aactgcttct gacatcatac gatataaatc taatgactca
     9241 ggcgttgtca aatgggattt gaaatatgtt ttgccatcta acgttgtatt catagtagaa
     9301 agcaatgctg tttttttatt tgttgtgtga tccaagattg cttttgtaaa gtacgcagca
     9361 gttgttttac cttttgttcc agtgaatccg atcactttca atttattttg cggatagtcg
     9421 taaaaagcca tagcaagaag cgccattgct ttacggatat ccgttacgat gattcctact
     9481 gctgaatttt cgtatggttg ttctgataca taatattgaa taccctgttc gattgctgaa
     9541 tccaaatatt cttctttgaa attcattcct ttacagaaaa acaaagtaga agcatcagct
     9601 tttcttgaat cataacttaa ctgaagaaat tcagcttttt ctggtacatc aagatgccag
     9661 cctcttgttg aaacaaattc ttttaataga ttttctttta atagtaaatg acggatgtct
     9721 tctaaagaga agctcattga ttgatccctc gctttattca atttcttggt ttattatagc
     9781 acactctttt taatatatcg tttgtttccg ctatgacaaa atccagcttt attcaaattt
     9841 tcttgacaca ggggacaagc ggatgagtat tttcataaac aatgaactga ctgtaataga
     9901 taggagaacg aatagtgtct ccaacaatcc aaaaacataa taattcaaaa agacgataag
     9961 actattggta agtaaaagtc cttgcggcat tggaagccga aaaaatttgt ggaaaataat
    10021 cggcggtatc gttataccgc catttgaggc cccgactgtg tacaatgtgt aaaccccaag
    10081 actgaacaaa agacttcctg aaatcagtga aaagaaatgt gaggagatca tttccacttt
    10141 tggaacaatc tctaaaacaa caggaaaaag cagacttccc gctacagtct taaaaaatac
    10201 tgattttcct aataggacag cggctagaag cagcatcata agattgatgc tccaaacagt
    10261 aactgagcgt tggatagaaa aggccgtttc aactaaatgt ccgatggcgc ccactccggc
    10321 ggaagctata tcgtgaggga gcaagaacca attcaatcca actgtgataa agaaaagacc
    10381 taaaaatata acgggtagtt tttttatttc ttgtgtcatt gatatctcct ataaatgtta
    10441 gccataaaag gctgtatatt tctttacttt accaaaaaaa cgaaaccgaa ttcaaaaaaa
    10501 caattgttct tataaaagtt atataaaatc gattgccagt ttctgtttta ccaattaaaa
    10561 tgatagtaat gttttgtaga aagttggaat ctgaccgatg gataatcaaa gaaaaccagc
    10621 attagatcaa ttaacaccgc aagaaaaaat ggcacgaggc tctgcttgga tgaccgccag
    10681 taatatcatt tcaagattgc taggcgctgt ctatatcatt ccctggtatg cttggatggg
    10741 cgaaaatgct aaggctgcca atggattatt caatatggga tacaatatat atgcattgtt
    10801 tctactgatc tctacagcag gaatacctgc tgcgattgca aaacaaactg cacgctataa
    10861 ttcattgaat gaatatggca cttcacgacg attatttatc cgtgcattac agatgatggg
    10921 cgggttaggc ctgttgtttg ctttgttcat gtacatcgcc tctccttggc tagctcatgc
    10981 ttctggtggc ggagaagaac tgattccaac gatgcgttct ttgagtatcg ctgtattggt
    11041 ttttccttgt atgagtgtga tacgagggta tttgcaaggc aatcaagaaa tgatgcctta
    11101 tgcgctgtcg cagattgtag aacaggtggc acgtattttt tatatgctat tggctacatt
    11161 catcatcatg aaagtcatgg atggtgacta tgtgacggcg gtcacgcaat caactttcgc
    11221 ggcatttatc ggtatgctag caagtattct tgtccttttg tattttttga agaaacatca
    11281 agcgtataca tcggcgttta ttcactacag cgaaaacaaa ataaatattg caacgaagga
    11341 attgttgtta gataccgtta aagaagcgat tccgtttatt attgtgggtt caggggtaac
    11401 gatcttcaaa ttagtcgatc agttcacttt tatgaagatc atgtctgcat ccaccgagta
    11461 ttccaatgca cagttactgg atcttttttc gatttttagt gccaatccag ataagttgac
    11521 gatggtagtt attgcattgg caacatcgat cgcgtctact gggttaccgt tgattacaga
    11581 agctgttacg ttgaaagatc gagtaggtct ggcaaaattg acaagcggaa atttacagtt
    11641 gttttcattt tttatgtttc cggcgacatt tggtgttatg ttacttgcct atccgctaaa
    11701 tacattattt tatacaccgg attctctagg aagtaatgta ctgatccaag caagttttgt
    11761 aggactcttc ctaggactat atatgctagt ttccaacatg ctgcaaggaa tgtttgaaaa
    11821 caaggcggca attaattatt tggttattgg gtttctagtg aaactccttc ttcaataccc
    11881 agccattcgt ttatttgaag tatacggccc tttattggcg acaatgatcg gatttgctgt
    11941 gtcttgtacc ttgatcttaa agagaatcca tgaagtagcc cgctttaaac caagttttgt
    12001 ctggcgcagg acattgctga tctttattct taccttgatt atgcttttgg cttcgtggat
    12061 cacaaagatg atttttggtg cttttttaaa cgaagatagc aaattccagt ctctattgtt
    12121 gattcttgta gtagcaggta taggggcttt agtgtatggt tatttagctt tgaaaatccg
    12181 cttggcagaa agactactag gaccaggaat agcgcgttta cgacataaat taaaaataaa
    12241 ataagtgaat cagaagagct agattgatgc tcttttgaaa tgggggaaac gcatgcgttt
    12301 agataagttt ttagcagata tgggacttgg cagccgcaaa gaagtcaaag gattaatcaa
    12361 aaaaggaacg atcgaagtca atggacaagt ggtgaaaagc gataaagcgc aagtaaatga
    12421 attcgaagat gcggttactt atttaggaga aatcattacg tatcaaaaag atttttacta
    12481 cattttgcat aaacctgcag gagtcatttc tgctactcag gataatcatg atcaaaccgt
    12541 aatcgattta ttggaagacc aggattatcg ggaagatctt tttccagtcg gccgattaga
    12601 taaagacaca gagggcctct tgattttaac gaatgacggg gtgtttgccc atcagttact
    12661 atcacctaaa aaacatgtgg agaaagaata tctagctgag gttagcggta taatgacaga
    12721 agaagatatc cgtttatttg cagaaggact gattattgat ggcgatgagc agacattgcc
    12781 ggcaaaactc caaattgatc aagtagatca agagacagaa acttcaatta tccgtctgat
    12841 tttgcatgaa ggaaagtttc accaagttaa gcgaatggtc aaagcagtag gaaaagaagt
    12901 cttatattta aaaagaatcc gtatgggaaa attttggctg cctaaagatt tgaataaagg
    12961 gcaatatcga cccatgacca aagaagagct agaacaagtg agagaaaaat aattgaatgg
    13021 atagctaaaa gaataagcag agtagttgta gcgccatctg aaaagcagac ttgtccgtct
    13081 gactttcgga tggctttttt gtgaaatttc ggcttatttc cgtagaagct acttctggaa
    13141 caccgtttgt tcggaataag ggactgtgac aagacttttg ttacagtccc cattgttcct
    13201 tgtgactcag agttagatag taaggacacg atctccctaa tactcaggcc aaaacgctga
    13261 attcacaacc tctgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
    13321 ggcaaaatat gaggaactat tttcccgttt ttttctctaa tactcaggcc aaaacgctga
    13381 tttcacaacc tctcctatac tttgtttcat tttccctata ctttgtttat ttattctcat
    13441 tattgaaagc gctataatta cgttgcgaat gaatcgaaag gggtttttag atgaaaaaac
    13501 gaaaggggtt caatcatttt tttatgaatc tatggcgtta taaagcactt gtcctgatgg
    13561 ctgtaccggg tatgctttgg atgatttttt tcttttacat acctgtaatg gcgaatgtcg
    13621 tagcattcaa aaattttcat atttcagcag atgggttctt ggctagcttg agggaaagtc
    13681 cttgggtggg ttgggaaaat ttcaaatttt tattttcttc ggatcaagca tttctcatca
    13741 ctaaaaatac aattttatat aatgtagcat ttatcctttt gaatctgctg atctcagtcg
    13801 tatttgcaat cattatgagc gagttgagaa ataaacgact cgttaaagtt tatcaaacga
    13861 tgtccttact accttatttt ctatcttggg tcattatcag ttactttgtt tacgcttttt
    13921 taagtcctga caaaggaata ttcaatcagt ggatcactgg acatggagga gaagctgtca
    13981 attggtataa tgaaccgaaa tattggccgt ttatcttggt gttcattggt acatggaaag
    14041 ggattggtta taacagcatt atttactttg catctgttat gggaatcgat ccgacttatt
    14101 atgaagctgc tatggttgat ggagctagca aatggcagca gatcaaacat gtgacgatac
    14161 cacaacttat tccactaatg acgattttaa cgattttagc cgtaggaaac attttccgag
    14221 ctgattttgg cctgttttat aacattccta ggaattccgg tgcattatat gatgtgactc
    14281 aagttttgga tacgtatatc tacaatggcc tgacatccac aggagatttt ggtatgacgg
    14341 ctgctgcagg actttaccaa tcagttgtcg gctttgtctt gttgatgatc acaaatacga
    14401 tcgcccgacg ttttgatagc gattctgcat tattctaagg aggaaaaaaa tgaaaaaaaa
    14461 gaaagtggag agagtccaag tccgctcttt caataagacg gctaattttt tctctaatat
    14521 aatgattgca ctctttgcta tttcctgtat tttgccattt atatttgtta tcgccatctc
    14581 ttttaccgat gagtccatat tgtcgactca cgggtacagt ttttggccag aaaagttcag
    14641 tatatttggt tatacgtact tgttcgacca gatgcaggat aaaattttcc aagcgctttt
    14701 cgtcactgta cttgttactg ttttaggtac actgatcaat agcacggcta cttctttata
    14761 tgcttatgcg atttcacggt caaactttcc attccgtcgt ttttttaccg ttttttgttt
    14821 gattacgatg ttgttctcac cagggatggt ggccaattat cttgttatga caaatcttct
    14881 tcagttaaaa gatacgattt gggcattgat cttgccaatg gctgtcagtc ccttcaatat
    14941 tattgtgatg cgcacattct ttaaacgttc ggtctctgat tcgattattg aatcggcacg
    15001 gatcgatgga gctagcgaac tgcgaatatt tgttcagatc gttttaccgt tagctgttcc
    15061 aggtattgcg acaatcagtt tatttgccgc attgggttac tggaatgact ggttcaatgc
    15121 tttactatac atccaagatg ataagctagt tccactacag tatcttttga tgaaaatcca
    15181 aagtaatatt caatatctga cacaaaattc aggagcagga agccaattga caggcggatt
    15241 agcctcagtt ccaggagaat ctgccagaat ggcgatcgta gtcatctcga cgttgcctat
    15301 tgcgatcagc tatccatttt tccagaagca ttttgtcaaa ggtctaacaa tcggcggagt
    15361 aaaagaataa agaaacaaaa atataaatca taaaattagg aggaagaaaa atgaagttat
    15421 ggaagaaact agcctttaca ggtgtttcag cgttgttgtt gggaacatta gcagcatgcg
    15481 gaggttctgg ttctaaagac caggcagaag ctagcaattc ggacactttg cagatgtatc
    15541 aaatcggaga taaaccagat aatttcgatc aattgatgga agtagcaaac aaacgaatcg
    15601 aaaaagagat cggtgtaaaa gtcaatatca attacattgg ctggggcgat tacgaaaaga
    15661 aaatgaacgt catcatttct tccggggaaa attatgatat cgcctttgcg aacaactatg
    15721 tttccaatgc ccaaaaagga gcctttgctg atttgactga attagcgcct aagtacgctg
    15781 aaaaagctta taatgattta gatgaagcat atattaaagg aaatctggtc aatggaaaat
    15841 tatatgcttt cccagtcaat ggaaatgtct ttgctcaaca agtacttact tttaacaaag
    15901 ctttactaga taaatacgat ctttcaattg atggaatcca atcttacgct gatgcagaaa
    15961 aagtcttgaa ggaattccat gaaaaagaac caaacacggc agcttttgcc attggacaag
    16021 gcttcaaagt ccaagggaac tttgattatc ctttagggaa tacgttacca tttgctattg
    16081 atctggatgg agatgattcg aaaatcatca accaatacga taatgaaacg tatatcggac
    16141 tgttacgtac aatgcatagc tggtacaaac aaggactcat tccaagtgac gctgcaacga
    16201 gcaataagga ttatccacta gaaggaaata cttggctaat gcgtggagaa acacaaggac
    16261 cgtatgatta tggcgataca attttgacaa atgcagcaaa acaagaactt gtctcaaaag
    16321 caattactgt tccactaaaa tctacagctc aagcacaaat ggcaaatttt gtcgtatcaa
    16381 atacttcaaa aaataaagaa aaatcagtag aacttctagg gctgcttaac agtgatccag
    16441 aattattgaa tgggcttgtt tgggggatcg agggagaagc atgggaaaaa gtcgatggtt
    16501 cagatgataa aatcaaattg ctagatggtt atcagccaaa tacacatatg tctgcttgga
    16561 atacaggaaa caacaagatt ctatatacac aagagtctat tacggatgac atgattgcca
    16621 aacgtgatca atcgattgct gatgcagaaa cttcaccgat tttaggattc agcttcaaca
    16681 ctgacagtgt caaaacagaa ttaagtaata tttctaatgt catgaatcaa tatttagatg
    16741 gattgaatac agggactgtt gatccagatg aaacattacc gaaattgaaa gacgctttgg
    16801 acaaggctgg ctatgataag gtattgaaag aaatgcaaaa acaatatgat gagttccgac
    16861 aagaataata atgaataaag acaaaggggt tgtgacaaaa gacgtgtcac aacctcttgt
    16921 tccgaataaa cggtgttcaa aagccagttt ctcggtatta agctaaatat atgtaaaaat
    16981 gtggaaagcc atattcacaa aatttttctt actactcgaa actaagcggc tatttcacaa
    17041 actcttggta aacggtgttc aatcagctaa ccctcggtat tcgctcacaa aacgacaaaa
    17101 tatgaggaac tatttttccg tttgtttctc taataatcag gtcaaggtgc tgattgccca
    17161 accttttttt gtataatgag aaagtataaa cttaatgttt ggaggagaag atatgttagg
    17221 gaaggttttg gaagagttat ttatccggat ctgggtcatt ataaaactaa ccttgtattt
    17281 ctggatatat acatttgccg gcgggatcat ctttggatta ggtgcggcat ggaaaacagt
    17341 caatgaacta ttttatttgt acggattcga gtataaagaa atcacaataa aaagaggctg
    17401 gaatatatat aaaagaaatt ttttaagagg caatctgcta tttagtttat ttttatctgg
    17461 tactgcttta ttgagttaca atttatattt atctgttcaa atcaaagggc tcattttttt
    17521 agctattgat tttattttac tttttgcctt gctctgccta tttgctactt atcaatacag
    17581 tatgatttta gatagtgaat atacgatctc tgttcctaat ctgctaaagc taagttttat
    17641 ttcggttttt tccagctttt cgtcttttct aaaaataatt attggtagcg gtataatttt
    17701 aggcgtgact tggcaattca aaggattgat cctgtttggt gtcattggtc ttttgacggt
    17761 ttggaatggt acgatgacaa cacattggcg tgaagaatta gataaacagt tggaaagtta
    17821 tgaataagtt tcggattcta ttttcaaaag gaaccttact aaatcgtctg ttgcggaaat
    17881 acgcggttat catgatcggt gtaacgatga ctgctaccgt tatttttagt atccatactt
    17941 gggaacaaaa tcaaaaacag gcagaaaaca tgacaagtga tgccgttcaa agcacaagca
    18001 gaatgctgaa tgataaaaca accttgagta ggatcatcaa aaaccagctt gtagggaatt
    18061 ccgaaaagat cgaaaatgtg acgacctact taacaaaacc catagatcag tatctgatgt
    18121 atgtatacga acagcaaaac agtaccgatg aattagtttc tttcccaaat caaatcaaag
    18181 atctctacgc aaattatgaa gaactaagtg cgatatatat cgtgttgaat caactaccgg
    18241 agtattatga atcttctaga gaaaacaaag gtggggaaat aaaaaagggg acaccaaaat
    18301 tactagacgc cttttatatc aagttgccta tcacacaagg aggagctgag tcaggaagta
    18361 tttttattgg ttttcaaaag aaagaactag atatgatttt agaaaatcta acgtcattca
    18421 atggactctc tttatacatg atttctggaa cgacaaatcg actatacaca ttccatgata
    18481 ataaaatagc taaagaaacg tttgaaagac aagaaatgat catcacagag agtctgaaga
    18541 aaaattcaca attgccgatt gacgatctgg aaaaaaacaa ttttgttcaa caccaagaac
    18601 tgtctgatga ttatcgtata ttagctgtac tagataaaaa aagtgtaaaa atcgaaacgg
    18661 gaaaaaatct tgccccgctg atcattggta tcattatttt agacaatata ctgcttatct
    18721 ttctttataa aacattcaaa cgatattcac agcaagtatc tatcgtcatg caggccatgg
    18781 atcaaacagc agcagggaat ttagagacgc ggatcgacat aacaaacacg gaatatgaac
    18841 tgagggaact ttcaatcggt atcaacgaaa tgttggatag catcaatcag tttgtagaag
    18901 acatctacaa attagaaatc aaacagcaag acgcacatat gcgggcgctt caagcacaga
    18961 tcaatccaca ctttttatat aatacattag aatatatccg aatgtatgca atcagcgaag
    19021 gaagtgaaga attagcagat gttgtgtatg cgttttccgc tttgcttcga aacaatacga
    19081 atcaagagaa aacgatcact ttaaaagaag aactggactt ttgcgaaaaa tatgtctatt
    19141 tgtatcaaat gcgttatcct aatcgagtag cctatcattt tatgatcgat cctgatttgg
    19201 aaaagatcga agtacctaaa tttgtgatcc agccattagt tgaaaattat tttaaacacg
    19261 gtattgattt tactcgattc gataatgcgc taagtgtcaa agtcttgcag gaaggcaaac
    19321 gggtaaggat catcatcaaa gataatggaa aagggatgac tgaaaaacgg ctaaaacaga
    19381 ttgaagaaaa actgtctcat cctaaagtgg aacttcacgg ttctatcggt ctgcaaaacg
    19441 tgaatgaacg tttacgtgcc agcttcggca gcagttatta tatgtcgctt gagaataatg
    19501 agacaggtgg actgaccgtt tctattacat tcaaggaggg atgagcgtgt atcaagtgtt
    19561 attggtagat gatgaataca tgattttgaa tgggttaaaa aagataattg attggcaaag
    19621 tttaggcttt caaatagtag caacagcaga gaatgccaaa gaaggactag ctgtacttga
    19681 acagcgacag attgatttag tagtaacgga tgtgacaatg ccagaaataa atggactgga
    19741 atttattgaa gcggctcaaa aagaacgtca taattttgaa tttatgattt tatcaggata
    19801 ccaagaattc gattatttga aaggaggtat gcaattaggc gccgtgaatt atttgatgaa
    19861 acccgtgaat aagttcgaat tggttgaaag cctcaagaaa atcaaaacac ggttagatca
    19921 gcaaaatgaa caaaaaaatc aacaagaaat ctatcaagaa ctgttattca gtcaatggtt
    19981 gaatgaagaa ttggatgaaa taagtgaaga agaaataata ggacaaataa gtgagaagca
    20041 gcataggata gtattgattc aactggcaag aactcatgat actcttatca atagatggtt
    20101 gcaagaacgg caacaaatct tttactatca acgaaattac ggagaccgtg tattgatcac
    20161 gttgttgttg gaggcagatg aagttgatgg cttctgttgt tttgttcaag aaaactttcc
    20221 tgatcaggaa tggctgatca gtatcgggga agagacagat tctttggaca aaatccctga
    20281 aacattccaa caagcgaaag acaatctaca gttgcatcaa ttttatggag ataaagacga
    20341 gcatgttttt tacgcagtac aagcagaaac aaaagatcaa accatcgatt tttcaagttt
    20401 cagacgcgtg ctgcaaaata aacaattgga agtcgctcaa aaaatgatca ctgatttttt
    20461 tgaacagttt cagttagcag ccatgatgcc ggaagatata cgatattcca gttttttact
    20521 gtttatggag attcaacggg aattgattga tctggaagat gaggaatatt tacaaggaat
    20581 cgaaaaaatc catcaggcaa aaacggtgca agaacttcag cagctacttc tgtcattcat
    20641 caaaaagcat cagagacaga aaaagtacag tgacaatgtg gaaaaagtaa tcgtaatcct
    20701 gcaccagcat tatcaagaac cacttacact caaagaagtg tcagaaaacc tgcatttaaa
    20761 tgtcatgtat ctaggacagc tgttcaaaaa agaaacgaaa aaaagttttt cagcttattt
    20821 gaaccattta cgtatggaaa aagcgaaaca actgcttttg cacagtaatc aaaacatcaa
    20881 tgagatagca agtgagattg gctacaacaa caccacgtat ttctctaaat tattcaagaa
    20941 aatcgtcggc agatccccta aagagtaccg agaaaacagt ggagaatcat aaaagaaaaa
    21001 gccaatgtaa tgaaataact tataaaaaat tgtctagaaa tctaattttg ggctgttctt
    21061 attacttgag gcaaggcagc tttttcatga cctctcgata aacggagttc aaaagccagt
    21121 ttctcggtat taagccaaat ttatgcaaaa atgtggaaag ccattttcac aaaatttttc
    21181 ttaatactcg aaactaaaca gctttttcac gacctctcca ctaaacggtg ttcaatcagc
    21241 tgaccctcgg tattagctca aaaaatggca aaatatgagg aactattttg ccatttgtct
    21301 ctctaatact caggtcagaa cgctgatttc acaacctctc aataaacggt gttcaaaagc
    21361 ttgcatctgc ggtaataaga ccaaccaaac gaaaaatatg aggatctatt tttgcttggc
    21421 tgttcttatt acttgatgca ggacagcttt ttcacaacct cttgttaatt atagtttgat
    21481 aaggaaaaag gcaaatcttt tgcttgatat ttcttagggt gagggatgat ccctaattgg
    21541 taagagatcg tgccgccttt cagcaaatct tgatgggtaa aatataattt cgtatattct
    21601 ctgtccatcc gtttgatttt atggataaat tgttgctgcg gccgattagg cgttgcttca
    21661 atcgtcaatt cctttccatt tgacaaaagc aaaacagcct tgtcaattaa tggcataccg
    21721 ataacatatt caccggttcc aggcgtgaca ggataaaatc ccagactatt gaagatatac
    21781 caagcggcca tacttccatt gtcctcatct ccagggtaac ccattggaga atcgtcgaag
    21841 gtctgagtca tcaactgttt aagcagtggc tgtgccattt caggttgtcc tatataactg
    21901 aacaagtaag gatagtgaaa acttggctgg tttgaaatag ctaattgtcc aaattctatc
    21961 gcggccatct cactcatttc gtggatctca aaaccatatc ctcctgggtc aaacgttggg
    22021 ggctgattgc acagctcaat gagtttttct ttatatctct cactgccacc atattttccg
    22081 atcagtcctg aaaaatcgtg ataaacagca aagctgcttt gccaagcact tccttctgca
    22141 taatcttgtc cccaacgatt agctgaaaat ggttctctga acttgccatc tttatctttt
    22201 gaacgcataa atcctgactc atagtcaaag atattttgat agttcaatga ttgctgctga
    22261 tatttcttcg tcatttcctc ttcttctagt accttggcaa cttggctaat acaaaaatcg
    22321 ctataagcat agtctaatgt gtgattgact gattcgtggt agtgattagg aacatagcca
    22381 tatgtcaagt aatcttctgt tccttggcgt ccataatttg gatgtttgct ttgaaccgta
    22441 gcaccttttt ccattgccgt tagaaattca ggcatcaagt ctcgtcggat atcttttaca
    22501 gcagcatctg caatgaccgc atcgatcaat gtcccaggca taagtccacg ttcatcagga
    22561 gacagccatt ttggcaaata gccactttct ctatagctgt tcaaaaaacc ttccagcatt
    22621 tcttcgtatt tttctacagc aatcaaagaa taaagaggat aaaccgtttt atacgtatcc
    22681 caaaacccat tatttgtata gagaacacca ggttttatag atcgactagt cgtatcatag
    22741 tggatttttt gcccactagg atcaatttca taaaatgttt gtggaaataa aaacacccga
    22801 tataaattat gataaaacgt ccgcaattgt tgttgatcat ggtgtgtgag ctgtatacga
    22861 tcaaaatagg actgccattg ttcttgactg tgagcaaggt aagtctcttt gctttggttt
    22921 tgttctagtt ccaggttata agctgcttgt tccgagctga taaaagatgt cccaaatcgg
    22981 atagtttgtt tttttgtctg ttcaaaatac aacgggatcg agtcgctatt tttgttggaa
    23041 acagctaact catcaattgt taaaggatat tcaaatctca atataaaata aaaagaaaaa
    23101 tcaggatctt ctgaaccagc aaaatgtgtg atttttcctt ccactgtgta aggatctata
    23161 acaaagagct gatggcgtcc cggaaaggat aaaagtaaac cgctgtcatt tttgctgtaa
    23221 tcaatagata agattccgcc atacatgcta ggtatcaatg tagaacagat gccataacgt
    23281 aattgacaga tcgacagatg agtcgggcaa aatatacttt cttctgggcg gtaagaactt
    23341 tgagcatgga aaagggtgtt ctcctgtagt tttccattga tcggcgtaaa cagcatatga
    23401 ctgaaatcac ccatccaagg acttggttga tgggtaagac ggtagccttg aaaaacgcgg
    23461 tcatcaggat gaaaccacca gctgccgttt tgatccgtag tttgcggtgc aaaataattc
    23521 atcccaaaag gaacgccagt ataaggctgg cagttcccat tagagaaatt tggctgattc
    23581 gctgttgcat gtctagtatc tatttgaccg atattcattt tatttctcct ttgttgattg
    23641 tcttttgatg aatgaaactg gaaatttact atcggatggt cgatcttttg tctctaacca
    23701 agtgaccaaa gcatctcccg caagcttacc taactgttca aaatcttgtg cgatggttgt
    23761 cagtggcggg tcaacaagag ctgctgcttg gatatcatca aatccgataa ttgaaaaatc
    23821 ttcagggata tgataaccat gctgtctcaa gagattcatg gtctggatag cgacaacatc
    23881 gttttcacaa acaaaagcag ttacttcata cttagtgata taagaaagca attcatctaa
    23941 tgtcgcgctt ttgtcatcca gtgaagtgtg gaaagtcaaa ccagctttgt ccaatgcttc
    24001 aaggtaacca aggtaacgct gtcgaacgga ttgtggatga gtctgcgtac caaacaaata
    24061 agcgattttt gaatgtccct gttcgatcaa ataagaggca gcaagcgcac cgccttggaa
    24121 attatcggaa agaacggtag gaaaaggtaa ctcatagatt tttttatcta atatgacgac
    24181 agggaattct ttcaatgaaa gctcaaaaag taagtcaaga tgttgttctg tatcaagagc
    24241 ataataaatc aatccgtcaa attcattgat tagctctttt gctgttttat tttgtagaaa
    24301 gtcaagcgtc gtcatcatga catcaatctg tttatcttgc atcacagggt tcaatccctt
    24361 gctaaaatca ccaacagaca aatcagcgac atatggaaga agaaacagaa tccgtcgtgt
    24421 ttttgtagga gaagcaagaa tctgttccgg agaagcggat ttaacgaaac tgcctttccc
    24481 gcgaacgcga taaataagtc ctaattgctc taattcagtc aatgcacgtt tggaagtgat
    24541 tctgcttact ttataggtac gtgaaagttc tttttcagtt ggtagttggc tgtctacagg
    24601 taattcacca gttaaaatag ccgtttgcaa atcattaaat attgtctggt acaatggttg
    24661 agtcatataa acacctctta atgatatatc atattcaaat aataccataa tggatgaaaa
    24721 agtaaataaa aagatatttt ttgaaagcgt agacataatt ggctgtatga agtataatct
    24781 ttaaagatat atcaaataga aagaaggttt tattagtggt ttataaagat ataccaaaat
    24841 cggtgcagaa atttatggaa gatatcacac aaaaatgtgg ggatatccat gcggactggg
    24901 caaagaattt tacagcagca tttgccaata ctctgttgac aacagtcaaa aagcaaaatg
    24961 acggaaccac ctttttattg acgggagaca ttccagcgat gtggttaaga gactctactg
    25021 cacaagttcg tccttattta gtgattgcaa aagaagatga ggaattagct gacatgatca
    25081 gcgggttagt caaaaagcaa tttttttata tcaatatcga tccatatgcg aatgccttca
    25141 acgaagaagc taacggtgct ggccaccaaa cagatcatac aaaaatgaac gattggatct
    25201 gggaaagaaa atatgaaatt gattctttat gctacccaat acagttggcc tatcttcttt
    25261 acaaaaatac aggaaaaact gatcaattca atcaatcttt tattgaaggt atcaaaaaaa
    25321 tcttggacgt gttcaaaaca gagcaagatc atgaacactc tccttataca tttgtacgag
    25381 acacgacaag aaaagaagat acgctgatca atgacgggcg aggtgcaaaa acagctttta
    25441 caggaatgac atggtctggt ttccgtccta gcgatgatgc ttgccgttat ggatatctgg
    25501 taccatccaa tatgtttgcg gtggtcgtgt taggttatgt ggaagaaatt tttcaaacga
    25561 tactcgatga taaagaaatt gtacagcaaa cacagaaatt gaagaaagag atccaagagg
    25621 ggattcagaa tcacggacga acggttaatc aaaaagggca aacgatttat gcatatgaag
    25681 tagatggaat gggaaacgcc acagtcatgg atgacagtaa tgtgcccaat ctgatcgccg
    25741 caccttactt gggatattgt tctgaacaag aggaagatta tctgcaaaca agaagaacat
    25801 tgttgagtaa agaaaatcca tatttctatg aaggaaagta cgcaaaagga attggatcct
    25861 cccatacgcc agaaaaatac gtttggccga ttgcattagc tatggaagga atgacaacgt
    25921 cagacaaatc tgaaaaagag cggatattga atttacttgt agcaactgac gcaggaacac
    25981 accttatgca cgaaggattc gatgtgaaca atcctgaaaa ttatacgaga gaatggtttt
    26041 cttgggcaaa tatgatgttt tgcgaattag tcatggatta ctttgatatt agagtagaaa
    26101 agtaggaggt atcgtaaatg aaaaagaaag tatatatcat ttctcatagc cactgggatc
    26161 gtgaatggta catggcttac gaacagcatc acatgcgact gattgaattg atagacgatc
    26221 tactagagct atttgaagtt gatccgtcct tcaacagttt tcatttggat gggcaaacga
    26281 ttattttaga tgactatctt caagtaaggc cagaaaaaag acaggcaatc caacaagcaa
    26341 tcaatgaagg aaaattgaga attggaccat tttatatctt gcaagatgat tttcttatca
    26401 gctcggaatc gaacgtgaga aatatgctga ttggcatgga agaaagccgt aaatggggaa
    26461 cccctgtcat gttaggctat tttcccgata catttggaaa tatgggacag acgcctcaat
    26521 taatgaaaca agctggtatt tcagcagcag cgtttggccg tggtgtaaaa ccaattggct
    26581 ttgataatca agttttggaa gcagaaaact attcttccca atactcagag atgtggtgga
    26641 aaggccctga tcaaacagca atctttggtc tgctatttgc caattggtat agcaacggga
    26701 atgagattcc agtagaaaaa gaagcagctc ttgccttttg gaagcaaaaa ttagcggatg
    26761 cagaacaata tgcctctacg aaccacttat tgatgatgaa tggtgttgat catcaaccgg
    26821 tacaaaaaga tatatcaaaa gcaatccatc tcgcaaatga actgtttcca gattacgagt
    26881 ttattcattc taattttact gactatctgg aagcagttca aaaagatgtg ccagaagact
    26941 taggctcagt agaaggagaa ttgacaagtc aagaaacgga tggctggtat actttagcca
    27001 atacagcatc tgctcgggtt tacttaaaac aatggaatac caaggtccag cgacagctag
    27061 aaaatattac agaaccactt gcgacgatgg cttatgaagt tagtggaaac tatccccatg
    27121 atcaattaga ttatgcttgg aagacattaa tgcaaaatca tcctcacgac agtatttgcg
    27181 gttgttcagt cgattctgtc catcgggaaa tgatacctcg ttttgaaaaa gcagatgaag
    27241 ttggaaagta tcttgcacaa gattccttag aacagctgac cgcagcaatc gatacgaccg
    27301 gattcccaaa agacagcttt ccatttgtca ttgtaaatac tgcaggaatg gataaaactg
    27361 gtgaagcaga aataaccatc gaattagaaa gaaaaagatt cgctgaagga atacctgaac
    27421 aactatatca agagttagaa aatttgccta aacgtaagta tcatgtagaa acaaaaagtg
    27481 gggccactat accagctatt ttatctgaag aaactgtcca atttggttat gatttgccga
    27541 aagaccgttt ccgtgtgcca tatatggcaa gaatgatcaa agtgacttta ccattagaaa
    27601 acatgccagc attttcttgg gaaacattcg cgcttgtaga aggggaagcg aaagcagaag
    27661 aaaaggaaac aatgattcat cagagtggac gaatcatcga aaacggccct ctacatttga
    27721 cgattgaaaa aaatggtacc attacaatgg aagatcgcaa aaacaaacga aagttgaata
    27781 atctgcatat ttttgaagat atcggcgata taggaaatga gtatatcttt aaacaacctt
    27841 tctgtgatca gccaatccta tccagtaaca aagaaaactc tgaagtaaaa gtattagtag
    27901 atacaccgga aatagcaaaa ataagtattc tacaggaaat ggaaatccct gtttctgcag
    27961 acgagcgttt agaaaaagaa cagcagatgg ttgtggaatt tcgttatcga aaagcagaac
    28021 gatccaaaga aaaacgaatc cttcaaataa aaacaatcat gacaatcaga aaagatagta
    28081 aaaaaatcga ctttgaaacg actctcgaca atcagatgaa agatcatcgc ttacgtgtct
    28141 tgtttcctac aaagttacat gtggaacatc acgaagcaga tagtattttt gaagtggtga
    28201 agcgcccaaa ccatgtgtct aaaagttggg aaaaccccac gaatccgcaa catcagcaag
    28261 catttgtcaa tattcatgat gaagagtacg gtgtaacagt cggaaacttt ggtttgaatg
    28321 aatatgaagt aacagaagac ggacaaatcg cagtgacgct acttcgcagt gtgggagaac
    28381 taggcgattg gggatatttt ccaacaccag aagcacagtg tctaggtgag catcggttca
    28441 attacagcat tgaactacat ggaccagaag aaaaattctc tacttatttg catgcatacg
    28501 cagcacagat tcctttttcc actcaacaaa tcaaacatca tgaaggaaca ttgatttcaa
    28561 aacaacaata tttaacgata aaaagtgaaa cgtttgcaat tacagctttg aaacgcagca
    28621 agtttagtga taaagtagta gtaagaggtt tcaatatgtc tagtcattta gaaaaattgg
    28681 aaataactaa agacaatgga aaaactgtca tattgaatct gcttgaagaa ccaacgaagc
    28741 aagcggttgt cccaataatc caaccttatg agattcggac aatcggattc gaggaggaaa
    28801 acgaatgtat ggcggaatag aagcaggcgg aacaaaattt gtgtgtgcgg tttcagatgg
    28861 tggagaaatt ttagaaaaat taagtatccc taccacaaca ccagaagaaa cattggatca
    28921 ggtatttgaa ttttttgatc gttatgaatt gaagggaatc gggattggct cattcggccc
    28981 gattggtatc gacaaaacaa aagataatta cggatacgtt ttggcaactc ccaaaaaagg
    29041 gtgggcacaa ttcgattttc ttggcacaat caaggaacgc tacaatattc ctgctgcttg
    29101 gacaacggat gtcaatgctg ctgcatatgg ggaattgaag caaggagcag cacaaggaaa
    29161 aaatagttgt atttacctta ccgtgggaac aggaatcggt gcaggtgtcg tgatcaatga
    29221 agaaattttt tcagggatcg cacatcctga aatgggacat atttgggtga aacgccatcc
    29281 agatgaccat tatgaaggta cttgtcctta tcataaagat tgtttagaag gattagcagc
    29341 aggaccgtct attgaggcac gcacagggat caaagggcaa gatctgccgc aagatcatcc
    29401 tgtttgggct attcaggctt attatattgc tcaagcactg atcaactata cgttgacgtt
    29461 agcacctgaa aagattattt taggcggtgg ggtaatgaat caggatcatc tccttcaaaa
    29521 aatccgtcag caatttgttg aattgatggg tggttatatg gaaacacctc aagtaagtga
    29581 atatatcgtt cgttggggac tgccgaatga aagtgggatt atcggtagtt tgctgttagc
    29641 agaacacgaa catcaaaagt aagcagacaa attacacaaa aagaacagag tcttatcatt
    29701 atctgctgat aagactctgt tcttttttat ttctattccc ataatccagg taaagcttta
    29761 ccgactattt tttcttgagt aaatggatgg atcatgtgca gttctaatgc atggagcatc
    29821 agtcgttcag ctgttctatt ttggtagaga gggtctccaa cgatcggatg tcccttatga
    29881 gctaaatgaa ctctgatctg gtgtgtacgt ccggtttcca aaacacaata gacttgtgtt
    29941 tgttcagaaa gtactttgtt gacagtgaca tgtgtcaagg cgctctgacc atttttatca
    30001 tctacgaccc tttttctccg atcatggcga tctcgtccaa ttttattggt gatggtcata
    30061 tctttggcaa tttctcccca tacgatggct tgatatctcc gatagatcat tttttgttcc
    30121 aacattcttc caagtatcgg caagacaaat ggattttttg caaataaaac ggcaccgctt
    30181 gtttctttgt ccaagcggtg gacaacgtaa ggtcgttgct gtttagtgtc gagataagca
    30241 gctaaatgat tgagtaaggt actgttttct gtcggttcat ttggatgagt cttcattcct
    30301 gcaggcttat ccactataat caaatgctca tcttcatata aaacacggat gtgcttcgca
    30361 tctcctaatt gaacttcttg ataattataa tctgtttctt cgaataacaa tgtgatctgg
    30421 tcattgccct ttacttcatg atggaacaaa gcaggttgtt gattgatcca aacgttttta
    30481 cgtatacgca aaaagtgtcg aacctttcta ggaactaacc attccttttc aagcaagtcg
    30541 cgaattgttg tttcaggatg gttcataggt aaagtgatcg tgattttcac aagtgtactc
    30601 ctttcagtgc aattgcagac taattgtacc atttttaaaa catatttaag aaaaaactta
    30661 catttttctg ttcattctta tgttactcta cttgcactaa cgtaaaaaaa catattgaac
    30721 tacaacttaa gcaggaagaa aacactcttt cactatggta aaataagacg attgaatcaa
    30781 atagacagga gaagaagcaa atggattttc aaagcatttt agaaaagata aaagctgctt
    30841 tgatcagttt ttggcgttgg atcagaccat atctcggaca attccatcga tggcgaaagc
    30901 gcatctggaa aaaatatcat gtgaacaaat tgattttgct gattggtttg atctgtgtct
    30961 tagtgacaag tatctacctc tttattttag caaaacaagc aaatgtcgaa acgttaaaat
    31021 caggattaag ccaatcgaca gtcatttatg ataagaaaaa cgaagaagct ggcacactgt
    31081 acgcccaaaa aggaacatat gtagaattaa acgcgatttc tccctatatc caagatgcag
    31141 taatctcgac agaagatagg aatttttacg agcatcacgg gtttgatatc aaagggattg
    31201 cccgtgcagc agtccgaatg gtcttgtctg gcggaacatc agggggcgga ggaagtacga
    31261 tcactcagca gcttgccaaa aatgcgtatc tgacattaga ccaaacgttt gatcgaaaag
    31321 cgaaggaatt atttttggca atcgagatcg aaaagaagta cagcaaagaa gaaatcttga
    31381 ccatgtatct taacaatgcc tattttggca acggggtatg gggtgtccaa gacgcttcca
    31441 gaaagtattt tggagtagat gcaacgaatg ttacgctgtc tgaggctgct actttggcag
    31501 gaatgctgaa aggtcctggt atttataatc cgatcgatca cccaaaaaat gcgaatgatc
    31561 ggaaaaacac agtactaagt gtaatggaag aaaacggaaa aatcacaaaa gaacaagaac
    31621 aagcagaaag ccagacagat atcagcgcgt atcttaatga cacatacgat aattcagatt
    31681 ctggttatcg ttatccttat tattttgatg cagtgatcga tgaagcagtt aacgagtatg
    31741 gtcttgatga agaagatgtc atgaataaag gctataaaat ctatacagct ttagatcagg
    31801 attatcaaaa gcaattagaa gctacttatc aaaacagtgc attattccca gcaaatgctt
    31861 cagatggtgc catggtccaa tctgcttcag tagctttaga tccgaataca ggtggtgtac
    31921 aagcactagt aggacgaaga ggagatcatg tctttagagg attcagcttt gctacacaga
    31981 tgcgtcgttc accaggatca acgatcaaac cattaagcgt atatacacca gcactggaag
    32041 ctggatacaa gccttccagt atcttgaaag acgaaccgca aagttattac gatgcgcata
    32101 attttgacgg gacataccaa ggagaagtac cgatgtatca agctgttgca caaagtttga
    32161 atttgcctgc tgtatggctt ttgcatgaga tcggtttaca aaaaggatat gataaagcag
    32221 aagaattcgg cctgccttta gcaaaatctg ataagtatta tggcttagcc cttggtggac
    32281 tggaaaaagg agtatctcca ttgatcatgg cgggtgctta cagtgcattt gccaatgatg
    32341 gtcagatgta tacgccgcat cttatcacga aaatcgttga ttcgactgga gcggtgatcg
    32401 tcgataacac aaacaaaaaa ccaaaacagg tcatatcaaa ggaaacagcc gatgaaatga
    32461 ccagcatgct tcttggtaca ttttcaaatg gaacagcggc tgctgcgaat cctgcaggtt
    32521 atacgatagc agggaaaaca ggaaccacag aaactaattt cgatgccaca aaagcaaatg
    32581 accaatggat gatcggttac acgccagacg tagtgatttc gacatggatg ggttacgaag
    32641 aatccagcaa gctgcactat ttggaaggga caagtggaaa tgttgtcggg aaagtcttca
    32701 aatcagcggc agaaggcatc cttccgtata cttcaaaaac aggatttagt gtagcagatg
    32761 cctatgccac aggaggacaa gtggtagctg cagatcaagt tggaaacaca ggaaattcta
    32821 atggagagtc tggaaattgg caagataact tgaatcaata tggtgaacaa gcaaaagaag
    32881 ggctgaaaaa cttcggcgat atggtgaaag aaggcgttca gggaattggt gaagcggcta
    32941 aagacctctg gcggaaatat caaggagagt agcccctttg aaaacgaata accccatgtt
    33001 acaatagaga gtaactacta aaagaaaaga gggcataaca tgtcaaacat ctacgatagc
    33061 gcgaatcaaa tcgaacgtga gatccgtgaa ttaccagaat tcaaagcgtt gaaagaagcg
    33121 tacgagaaag tacaagcaaa cgaagaagca cacaaactgt tcaaagactt ccaagcgatg
    33181 caaatcgaat tacaagaaaa acaaatgagt ggacaagagt tcagcgacga agatgcaatg
    33241 aaagcacaag aaatggctgt gaaaatccaa tcagaagaag taatcaatga cttgatgcaa
    33301 aaagagcaag gcttcagtac aatcatcaat gacttgaacc gtatcatcat gacaccagtt
    33361 cgcgaccttt acagcgaata aaactatttt atgaaacaac agagggtgtg aaagagacgt
    33421 tcggccttga gcgatgacaa aattgcttct tattgccgat aggctgtctc ttgaacacca
    33481 tttaccaaga ggtcgtgagc ctaccgttta actctgagtt acaaggaaca atttcaaaaa
    33541 acagcttctc atgtttgatg actattgtga cttgtgaccg aggagttggc aggagaacac
    33601 cgtttattca gaaataggag ctacgacaaa agtcttgtca tagctcctat tttttgtcat
    33661 tcatttttca agcggtagaa atagcctttt tgagctaaca gtttttcgta agtacctatt
    33721 tcaacgattt ttccttcatc gatcacaacg attttatctg cctctttgat cgttgaaagc
    33781 cgatgagcca caataaaagt agtgggtgtt tctgtcaggt aattcagggc ttgctggatt
    33841 tttttctctg actggttatc taaagctgag gttgcttcat ctagcaaaat gatttttggc
    33901 tgacgtatca acgctcgtgc aatggagata cattgctttt ggccaccaga cagcttgttg
    33961 ccatgttcgc ctactaaggt atccagacca tcaggaagct ggtcaatcag tgaagaaagt
    34021 tgcgcagctt cgatgacttc atctaaacgt tcttttgata cgtttttcaa gccataagtg
    34081 atgttctctt tgatcgaagc ggagaacaac aaagtggttt gaggaacaac ggctaaataa
    34141 tttcgcacac ttcgcatatc cagttcatcc aaaggctgat catctagaaa aatttttcct
    34201 gaagtcggct ggataaatcc aatcaataag ttaaggagtg tagattttcc agagccagat
    34261 ggcccaacaa aagcaattgt ttctccagct ttcacctcta gagaaaaatg atcgataatc
    34321 ggtttgagtg agtccggata aagaaaagaa acatcctcaa aacgaaaatt tccatccaaa
    34381 tgttggattt ttttcttacc gtgataagtt tctacatcgc cagcaatcaa cagttcgcca
    34441 atagaagtga tagattccat gccttttgaa atcgtaggaa tcagcgtgat cattccagaa
    34501 acggaattga cgatcgtcgt gaaatacgtc tgatacatca cgacatcgcc gggttggatg
    34561 cgcccttgta aagctaatat cccagtgaaa atcaaacaaa tcagctgaaa tatctgaaaa
    34621 ctagcccagc tgactgatcc gaaaacagat tgcaggatat ctaagtggaa tcctttttca
    34681 tagatttgag taaaatgctt atttaagcga gttgtttcgt gtttttctaa cccatgagct
    34741 cgagcaatcg gtgctaattc gatcacttcg atcacttttg cagaagtctc ttccatttct
    34801 tgcctgaagt ctgagttgga ctgtctgatc cttttacgga aaaagagagt aacgaatgcg
    34861 gcgagaggaa cagtcaataa gaaaaacatg aaaacaacag gacttttata aagcgtgata
    34921 cctaaagcta cgaataaatt gacagcgata tttaatccgc tgacaaatac ttgagaggac
    34981 aacgtttgga tagcttctac atcacggatg atctttgact ggattcgtcc agattgcaat
    35041 tctttttgat aaggaataga tagttcttgg attttcttga taagggtcgc tcttagtcca
    35101 gcttctactt gacggatcga agtgctatgg tattttacat gaaaataatt cgtcaatata
    35161 ttttgaccaa tcagacaagc catcaaaaaa gcgttgaaat aaatggcctg caactgagaa
    35221 gaatctttcg atgaagctgc attgattaca ttggcaatag cgatcggcat taaccaagat
    35281 ggaagatgtt tgataataaa aaagagtcct gacatggcaa aacgccaata atttccctga
    35341 taaagatgca gcaatgtctg aaaagcattt gcatgatatt tttgataact tttctgtatt
    35401 cgttcctcca taatcttctc cttaacaatc ttggtaaata aactgcaagt gttctattgc
    35461 ttcaggaaca taaatctcag gagtagcttc aagagtggcg tacattagag gacgctcata
    35521 tttgatataa tgcagtaccg ggcggaaatc taaacagccc ttgccaacag gtaccatgcg
    35581 gatctttcca ttttccatga tatagtcttt gagatgaagc gctgtaatat aaccatgtaa
    35641 attgtccaag gcacctcgga tcactttttc ctgatcagca tgattttctt tatgcatcaa
    35701 attcgcacaa tctaaaatga tttttaaatt tggtgaagct acttcatcga ttaaacgttt
    35761 agctaactga tagttataga ttggatgatt gatccctgct tcaacagcaa cagttacgcc
    35821 aaaattttct gcatgagcga ctaattcaat gatagaattt ctggcgatct gataagcttc
    35881 ttcagtaaaa ttttcttttg tgtaaccgac agagacacta ccggtttccg tagcaatcat
    35941 cttggcttga taggcagagc acagagcaat ttgctgtttg aaagttgcca atgcttgtgc
    36001 acgaacttct tgatttttgc tggataggtt gatatagcat cctaaaatgg aaagttcgat
    36061 attgtttttt tggaagtatt caccaaaata ggcagcactc ccaagtgtca tgtcagttaa
    36121 tttaagttgt tcaggaaatg ctttttgtgg tgcaaattgg atatgggaca agtgaagctg
    36181 tgatactttt tgaacgattt cttcacgatt tcgaacatct aaatcgtggg cacggatgcc
    36241 taaatttaat ggaaacatct caaactcctt tttgtaaata attagcaaga ggcagacggg
    36301 attcttttat caattcaaca attattcggg caactttatc agcgccttct ggactaaagt
    36361 gggtattgtc ttttagtcct tctgggtaat ttttacaagt atcaggcata agatgcaggt
    36421 agaatttttt tgtctcttct tttgagaagg tctggaacaa ttcttgtgat cttgagaaca
    36481 catctaaaag aggaatatgg tgtttctcag caaatgcacg catcgctttt ggatagtctc
    36541 caagtatatc tggattcaat gttccgtttt ctaagtaatc tcgtcgcgtc acagatgtca
    36601 gtaagaccat ttggacgttc gctttttttg cgcattcaaa aaatatctgc agatttttta
    36661 aatagctacc gaagggaagc gtacctcttt cttcttggat tttctggtcg ttatgtccaa
    36721 attgtacaaa taagaaatca ttcggctgaa actgtgaagc tagacgggct aaccttcctt
    36781 cctggataaa tgatttggtg ctgcgtccat tctttgcttg gttattgatc tggatctcgg
    36841 gtgaaaaata agcagagatt ttttctcccc aacctgtctc gggacgcttg ttttcatctt
    36901 tttctgccgc agtagaatca ccggcaatat ggatagtagg catgttatct cttctttcat
    36961 aaaggtttat aggcaatgaa gcagaacagc aagagaagaa gacggagcaa
//
LOCUS       DARBDN010000017        35632 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000017 DARBDN010000000
VERSION     DARBDN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.017"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            87..455
                     /locus_tag="SCH06_000903"
     CDS             87..455
                     /locus_tag="SCH06_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HEG1077501.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            920..1372
                     /locus_tag="SCH06_000904"
     CDS             920..1372
                     /locus_tag="SCH06_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077502.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(1496..2347)
                     /locus_tag="SCH06_000905"
     CDS             complement(1496..2347)
                     /locus_tag="SCH06_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HEG1077503.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2360..3145)
                     /locus_tag="SCH06_000906"
     CDS             complement(2360..3145)
                     /locus_tag="SCH06_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1077504.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(3497..4438)
                     /gene="ribF"
                     /locus_tag="SCH06_000907"
     CDS             complement(3497..4438)
                     /gene="ribF"
                     /locus_tag="SCH06_000907"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HEG1077505.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(4442..5365)
                     /gene="truB"
                     /locus_tag="SCH06_000908"
     CDS             complement(4442..5365)
                     /gene="truB"
                     /locus_tag="SCH06_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEG1077506.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(5733..8095)
                     /locus_tag="SCH06_000909"
                     /pseudo
     CDS             complement(5733..8095)
                     /locus_tag="SCH06_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            8543..8716
                     /locus_tag="SCH06_000910"
     CDS             8543..8716
                     /locus_tag="SCH06_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1077507.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(8873..9220)
                     /gene="rbfA"
                     /locus_tag="SCH06_000911"
     CDS             complement(8873..9220)
                     /gene="rbfA"
                     /locus_tag="SCH06_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEG1077508.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(9247..11553)
                     /gene="infB"
                     /locus_tag="SCH06_000912"
     CDS             complement(9247..11553)
                     /gene="infB"
                     /locus_tag="SCH06_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEG1077509.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(11566..11877)
                     /locus_tag="SCH06_000913"
     CDS             complement(11566..11877)
                     /locus_tag="SCH06_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEG1077510.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(11874..12167)
                     /locus_tag="SCH06_000914"
     CDS             complement(11874..12167)
                     /locus_tag="SCH06_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEG1077511.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(12189..13364)
                     /gene="nusA"
                     /locus_tag="SCH06_000915"
     CDS             complement(12189..13364)
                     /gene="nusA"
                     /locus_tag="SCH06_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEG1077512.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(13387..13860)
                     /gene="rimP"
                     /locus_tag="SCH06_000916"
     CDS             complement(13387..13860)
                     /gene="rimP"
                     /locus_tag="SCH06_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEG1077513.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(14005..18363)
                     /locus_tag="SCH06_000917"
     CDS             complement(14005..18363)
                     /locus_tag="SCH06_000917"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEG1077514.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(18575..20284)
                     /locus_tag="SCH06_000918"
     CDS             complement(18575..20284)
                     /locus_tag="SCH06_000918"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEG1077515.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(20352..21620)
                     /gene="rseP"
                     /locus_tag="SCH06_000919"
     CDS             complement(20352..21620)
                     /gene="rseP"
                     /locus_tag="SCH06_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEG1077516.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(21781..22581)
                     /locus_tag="SCH06_000920"
     CDS             complement(21781..22581)
                     /locus_tag="SCH06_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEG1077517.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(22578..23390)
                     /locus_tag="SCH06_000921"
     CDS             complement(22578..23390)
                     /locus_tag="SCH06_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEG1077518.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(23585..24142)
                     /gene="frr"
                     /locus_tag="SCH06_000922"
     CDS             complement(23585..24142)
                     /gene="frr"
                     /locus_tag="SCH06_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEG1077519.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(24145..24867)
                     /locus_tag="SCH06_000923"
     CDS             complement(24145..24867)
                     /locus_tag="SCH06_000923"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEG1077520.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(25003..25884)
                     /locus_tag="SCH06_000924"
     CDS             complement(25003..25884)
                     /locus_tag="SCH06_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEG1077521.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(25983..26765)
                     /gene="rpsB"
                     /locus_tag="SCH06_000925"
     CDS             complement(25983..26765)
                     /gene="rpsB"
                     /locus_tag="SCH06_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEG1077522.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            27124..27603
                     /locus_tag="SCH06_000926"
     CDS             27124..27603
                     /locus_tag="SCH06_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEG1077523.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            27820..28911
                     /gene="phnW"
                     /locus_tag="SCH06_000927"
     CDS             27820..28911
                     /gene="phnW"
                     /locus_tag="SCH06_000927"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HEG1077524.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            28904..29032
                     /locus_tag="SCH06_000928"
     CDS             28904..29032
                     /locus_tag="SCH06_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEG1077525.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            29036..29581
                     /locus_tag="SCH06_000929"
     CDS             29036..29581
                     /locus_tag="SCH06_000929"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEG1077526.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(30035..31726)
                     /locus_tag="SCH06_000930"
     CDS             complement(30035..31726)
                     /locus_tag="SCH06_000930"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEG1077527.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(32146..33093)
                     /gene="arcC"
                     /locus_tag="SCH06_000931"
     CDS             complement(32146..33093)
                     /gene="arcC"
                     /locus_tag="SCH06_000931"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEG1077528.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(33208..34227)
                     /gene="argF"
                     /locus_tag="SCH06_000932"
     CDS             complement(33208..34227)
                     /gene="argF"
                     /locus_tag="SCH06_000932"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEG1077529.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(34318..35547)
                     /gene="arcA"
                     /locus_tag="SCH06_000933"
     CDS             complement(34318..35547)
                     /gene="arcA"
                     /locus_tag="SCH06_000933"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEG1077530.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         9672 a         7608 c         6275 g        12077 t
ORIGIN      
        1 cattacttgt gttttgttcg ttttttatac ataactattg tttttctggt aaaataaatc
       61 aaaccactta atggaggcgt tttagaatgg aaaaatttca gccgatcatc aatcaaatca
      121 aagaaaaaga acatcaacaa aagatcaaag acctttttgc taagataaca gaaacgtatc
      181 cccagctaga cacaactgta aaatggaacc aacctatgtt tactgaccat ggtaccttta
      241 ttattgcatt tagttttgct aaaaatcatt tttctatcgc accggaaaaa gcagcgattc
      301 gtgcccttga aaaaaatatc caagaagcag gctacgtata tacggataac gtcatcaaag
      361 ttccttggaa aagtgtaatc aactgggaat tgattgaaca attgatttca tttaatattg
      421 aagataaaaa aggtcatgat aaattttggc gataaagctt tatacgaata aaccttttac
      481 tggcgaggaa actattcatc accttataca ggttttgttc aatcctatcc tttttatcat
      541 ccctggttaa acacttaatt gacaaagtat ctgctatttt tataaggagt ctttcttgtg
      601 ctgaaaaaaa tcactgattg aatggctttg aattttctac atagtaaaat tattttttca
      661 gcaattttcc tgcaaaactt ttgaataagg aaaaaatacg agaaaatatc agtgatcttt
      721 cataatactg cccattattt tcaggtatat ttaaatataa tatcacttta ggagagaacg
      781 aatttcttta gagaaataaa agttagaatt ttctgacttg atttttacaa tgaccttaat
      841 taaaatcgtt ctttctacat ttcgtgatta agcaaatatc aactaagtca gtagaaccat
      901 tcacatagga gggtgaacat tgaaagattt ttactcagta aatgaattag ccgaacaatt
      961 aggtgttact acacgttcta tcagaaatta tcttcatgaa ggaaaactaa aaggaacaaa
     1021 ggttggcggg caatggaaat tttctgaacg taatcttttt gagttcctat acggagatca
     1081 agcagaggaa gcagcaaaag aaatgcagcg attcatgcta aatgcaccaa tcacgatgcg
     1141 tttcaacctt caatatcgtg attttacagc aatcaatcaa ttccgagaac aattagtcca
     1201 gtaccataac gatgtttacg caaataaaaa agaccgtctt ttacaatacg atctttataa
     1261 agacaatcat gcggagatac taatcggtgg taacttcaat tatgtcgtaa actttagtca
     1321 atggatcaat gaaaaattat tgatccagac agatatttcc cttgtatctt aaacaattaa
     1381 aaagcgctag aaattccaga gatgttggaa attctagcgc tattttttta taagtactta
     1441 ctgtttggtt caaacaaata tttttttaat aaatgaaatt ttaccatctt tatcctcaaa
     1501 taaagaccgt gaccatgctt cctactacga tcagcaataa tccgataatc gttaattttt
     1561 tttcttttgg tgtcttattt tcatgcagga tgtacatacc gcctaatgta gagataacta
     1621 cgtttagctg tgtaatgata tatgcagtag caaccccatt ttcatttgct gaaaaaatat
     1681 aagccaatgc tgacacacta aagatggctc caacgatcgt tgctttccaa ctcttgtctt
     1741 cagaaaatgc ggttggttta cggaaaatca cataaatcac tgcccctaaa aagacaccga
     1801 tcatttgcgg aaagaaaatg gaaagtccgc ttgcatcaac tagtttaggc aatgcactgt
     1861 atacccaata accaatactt gttgatgcta atagactaat tccttttgtg ataccgcctt
     1921 tttttccagg atcatcactg attgccgtta aagcagaacc aaatacaaga agaatgattg
     1981 ctgctgctcc aatgattttc cccatacttc cagaccattc tccaaaagcg aagacaccaa
     2041 tcaacgaggt tccgactaac tgtaatgcag tcgaaattgg catcgtttta gaaacaccaa
     2101 tcaagttgaa agatgtatac tgtcctgttt gtccaataac ccaaaatgca ccagaaagta
     2161 aactaatcaa aaatgtagtc actgaaatac cagctggaga agcgaataat tgaacgagta
     2221 agccgacaag caccgctcca ataccagttc ctaatatctc atttgttggt ctgccaccaa
     2281 tctttttcaa aatcagtggc tggatccccc agccaactgc cgggatcaat gcaatcaata
     2341 aacccatttt tattcaccct tatccttttc caccttggaa agaaggatat aaagtcatcc
     2401 caccatctgc aaatagtgta atacctgtaa cataactgga ttcgtctgaa gccaaccatg
     2461 cagctgtcgc cgctatttct tttggttcac ctacgcgtcc tagtgggatc atactttcca
     2521 agagttcttt ttgttcagga tcatcaaatt ttgccgcatt aataggtgta cggatagcac
     2581 cagggcctat actattgatt ctgattccct tcggtgcata ctccattgct accgtttcgg
     2641 taaataattt taccccgcct tttgaagcag cgtaatgagc aaacgttggc catgggatct
     2701 gttcatgaac agaagacata ttgatgatat ttcctttttt attattctct gtaaagtaat
     2761 ttaaagccgc tttcgttccg ataaaaacgc cagtcaaatt gacttttaac actctttccc
     2821 aatcttcaag gctaagttca tgggttggat gctgattttc catcccagca ttattaaccc
     2881 aaacgtccag tgtcccaaaa ttttctaaag ccgtatcaag taaacgctgt attccttctt
     2941 cagaactgac atctgcttgt acagagactg cttttccgcc tgcctcttcg attgctttga
     3001 ctgctttttc tgctccttct ttatccgagt tatagttgac aactacattc attttttctt
     3061 tcccgaatcg ttgagcaatc gctgttccaa tcccctttga gccaccagtt actactgcga
     3121 ctttgttttc taattccttg tacatagtac ccactccttt ttcataccta aacctgttat
     3181 tacggataac ttttatttcc gccttaaagt gagtgtacac caagatatat agtctaaagc
     3241 aaatgatacg ctctagcaat cgttttcatg aattgctagt gtccttttat ttctataaag
     3301 aaagaggttg tgacagaagt ggtcagcttc aagaaatttc ggcttatttc cgaagaagct
     3361 acttctgaaa aaccatttat ttggaaaaaa aggctgtgac aagacttttg tcacagcccc
     3421 tttcctgggc ttatttatca cccattttat tgtaattgct agttatacat aaacaagaga
     3481 ttttatgcat aatgttttat tgctgagaaa aatattcagc tgttgcttgt tcatcctcct
     3541 tgagttgttc aatcaattcc tctacactag aaaatttcac ttgatctctt aaaaattgat
     3601 tccagcgtac cgcgacatgt tcaccataga tatcttgatt aaagtccaaa atatacaact
     3661 ctacagtcag ctcccgtcct tcaccgaatg tatcattatg tccaattgaa cccatggctg
     3721 gataccatgt ttccccaatt tttatttccg acacataaac accttcttta ggcaaatgaa
     3781 ccgtgctctt tactttgaca tttgctgtag ggaatcctag tagtctgcct cgtgcatcgc
     3841 catggacaac taccccttct acctcatatg tgcaacctaa tagttttgct gcttctttta
     3901 cttgtccgct gtctagtaat ccacgaatac gggtagagct gattttttca ccttgttctt
     3961 cttctttaga aactgtgacg attttgaatc ttcctttggc atattcagga aaatgagcga
     4021 catctgcaat gtcttttggt ccatacgtat aatcaaaacc ggaaacagca tattttgcat
     4081 gtaaccctac gatgtattga tcaacaaatt cctgcggtgc taaatgagca aaagaagaag
     4141 taaaatcaac ttcatataaa taatctatac ccaaagcggc cattttttct tctttttgct
     4201 taaggctagt caaatatttc acgctgctag gatcgatctt tttaaagaca atagatggat
     4261 gctgattgaa agtcatcaat gctaatttca atccttcttt ttgtgcaatt tccatacctg
     4321 tctttatgac tttctggtgt ccgatatgca cgccgtcgaa aaatcccagc actaaaacga
     4381 catcgtcttc tggaatttgt tctgattggt aaggatgtct gatcttgatg atattcattc
     4441 gttattcctc atttctcaat actttactag gttttaattt gtttttttct ttcgggtttg
     4501 gctgataaat actgacaact tttcctttat aaaacaaagc aatttcttct gacggcattt
     4561 ctgggagcgc aaatacagta taatcaagtc tcataccgtt ttttactttc tgccatactt
     4621 catcagtaat atctactcgt ttgaaccgtt ccactccttt ttctattggc agcaaacaat
     4681 catcgattgt cccatttttc acagcttgag ctacttcttc taatgtcaga gcatccttct
     4741 gggacatacc ggcacttgct gttcgggtca gatcagacat gtgcgcaggg taaccaagtt
     4801 tcttgcctgt atctacagct aatgtgcgga cataggttcc tttcccgcat tctacttcga
     4861 agcgccaaga aatggttcct gtcacttcgt ctcttgtcaa ttcacttgtc cggataaaac
     4921 ggtaaatctg agcctttcta acaggacgct ccactgtttc attattgcgg gcatattcat
     4981 ataaccgctt accgttgact tttaccgctg agtacattgg tggtatctgg gtgatctcac
     5041 caataaatga agccatcact tcatctattt ttttttcaga taaagacata tctactggtt
     5101 ttgtttctac ccgttctccg gatcgatctt ccgtcgttgt actgaaacct agagttatct
     5161 cgcctacata gattttccca gaatctgtca aatattcgat aacttttgtg gcttttccaa
     5221 tacaaatggg caacacaccg tctacgtctg ggtcaagcgt acccccatgt ccgatttttt
     5281 tcgtatgtaa gatttttctt aatttgaata cgcaatcatg acttgtcatt ccgcgttctt
     5341 tccataaagg taataacccg tccatgtctt ttctccattt catttttgat ttaactgaat
     5401 tattataaca cattgcatca attactgacg aatttgacat cataatgaac ggtttttatt
     5461 tttcggcaat aaaaacgtaa caaaattcat gctcacgtaa atagaaatca tgttatgctt
     5521 ttttaaagga gggaatagaa tggaagattt tttctttgca ccatttgatt ggatttatgg
     5581 gtggcttaca ggtaaatagt ttggttttca cttcccaaaa acgaaaaaaa agactggcca
     5641 ttcttccagt cttttttccg ttttttttat ttattttttc agtttcttaa tcaatgtaaa
     5701 aaattctatt ttgcgggatc gattttatca ttttattggt caagattttt ccatttccaa
     5761 tccaatactt ctggcagatc aataccattt tcacgaatat agttttgatg ttcttgtaat
     5821 ttctgatcca tttttttcgc aaaatcttct gcttgacttc ctttgatttt taaagctgcg
     5881 tcttttgcca aatgataacg atcaagttca tttactacac gcatgtcaaa tggtgtcgtg
     5941 atatctccat tttctttgta gccatgaatc attaaatgat ggttatgacg atcaaagaaa
     6001 atcgtgcgga ccaatgtttc ataaccgtgg aaagcaaata agatcggttt gtcttttgta
     6061 aaatattgat caaattcttc atcgctcaac ccacgcggat cttgacttgg atgacgtaat
     6121 ttcaataaat ctacgacatt gatgaaccga atttttagtt ttgggaattc ttccagcagc
     6181 aaagttacag ctgctaatgc ttctaagtta gattccgttc ctgcagcagc aatgaccaat
     6241 tcaggttcct cctcttttgc tgtcgaagcc caatcaatga ttttcaagcc ttcattcact
     6301 aagacggctg cttcttctgc tgagtaaaat tgagcacgcg gatgtttgga agagatgatc
     6361 aaattgattt tttctgacga gcggaatgct ttatccatga ctgcgagcaa tgtatttgca
     6421 tccgcaggca gatattcacg gatgaactcc gccttctttt ctgccaaatg tgtcaatatt
     6481 cctggatctt ggtggctata tccattgtga tcttgctgga agactgttga gcttgcaatg
     6541 agatttagcg aaggataatc atttcgccaa gaaaggtcat gtgatttccg catccatttg
     6601 aagtgctgag tcaacataga gtcaaccact cgcaagaatg attcgtaact tgcaaaaaac
     6661 catgccgtcc agtcagaacg tacccttcta agaacccttc atcttggtgt tccgataatt
     6721 gactgtcgat gacgcgacca gatggcgaaa gccattcatc attttctggt tcgatttttt
     6781 ccatccattg gcgatttgtc gttttgaaaa cttgattcaa tcggtttgat tttgtttcat
     6841 ctggtccaaa tatacggaaa ttttctggat ttttctcaat gatctcgcga acgaatttac
     6901 caagttcggt catatcttct gctttaacgg agcctggttt ttcaaattgc aaagtatatt
     6961 ttttccaatc tggcataata agcggtcttg gatcgattcc accattggtg ataggatttt
     7021 ttgccattct ttggtcacca gtaggcgcga tttctctgat ttcttctaaa atacgtcctt
     7081 gtgcatcaaa taatttttct ggttcatagg atttcagcca acggagtaaa gcatctgcat
     7141 gatccatatg ttcttgatct acaggaatcg gtacttggtg tgctcggaag gttccttcaa
     7201 ttggttcccc gtcccattct tttggaccgg tccatccttt tggtgtgcgt acgatcaata
     7261 ctggccattt tggcatcacg acatctgttg ctgtcttcag gcgagcttct ttttggatgg
     7321 atttaatttt ctcgattgct tgatccattt tttcagccat aacaggattt aatttttctg
     7381 aatcatttcc ttcaataaag aaaggttccc agccaagtcc gttaaagtaa tttgctaatt
     7441 ctccatctga tttacgtgcc aagatcgttg ggttggctat ttttgcacca tttaaatgaa
     7501 ggatcggtaa aacagctcca tctatcactg gattgataaa gacatttgag aaccagcttc
     7561 cagctaaagg accggtttct gcttcaccat caccaatcac gacagcagag attacttcag
     7621 gattgtctaa tacagctccg actgcatgtg aaagagagta tccaagctct ccgccttcat
     7681 ggatagaacc tggtgtttct ggtgctgcat gagaagcaat gcctccagga aatgaaaatc
     7741 gtttgaataa tttttgcatt cctgtctcat cttccgttac ttctggatag atctctgtgt
     7801 aacttccatc taaataagca ttcgatacca tgacttgtcc gccgtgtcct ggcccttcaa
     7861 tataaaacat gttcaaatca tatttattga tgactcggtt caaatggaca taaataaaat
     7921 tttggccagg aatcgttccc caatgaccga ttggatgttt tttgacatct tcgggtttca
     7981 gtgtacgtct cagtaagggg ttatctttaa gataaagttg cccaacagaa agataattag
     8041 cagcacgcca ccaagccgtc attttatcaa agtattcttt actagaataa tccatacata
     8101 acactccttt tcattattac tcttattcta gcgcagatac tcccaattga aacctaataa
     8161 gcacttctgt tcatttgttt ggattttata tctagccaaa tgaacaggta taaaaaacca
     8221 cgaaattttt cctttcgctg acgtttttta cattgatcca aaaaacttgt cgttatcaca
     8281 atggctgttc cgcagttcat ttcgctcctc atcatgcata atttgctgaa tgacgctggg
     8341 ccagttaaca cattgctgga aaactggggc tggatcgagc aattcctttc ctgattgatc
     8401 cgttttatgt aaaagtctct gttatctttg tcaatatgtg aattggtatc ccagctacta
     8461 tgctaatttc tacagggatt atccaaaatt tggatcgtga ccaaatcgaa gcggcgtaat
     8521 cggaaatatc aataacttca acgtgatttt tcttttaact gtcaacggac cgacaaactc
     8581 aaacttttat ggtgcaggtt ccactgatct tctagttact tggctatacc tgactgtcac
     8641 taaaatagat tacaatctag cttccgttat cggtatcttg atctttatct atatgcaaaa
     8701 atttatatac tactagaaaa aagaaagtcg aattttttac ttttcttttt ctcttttttg
     8761 gttagctgac acgccgcaag actaaagtca tggaactctt aggtaatacg tcttaatgaa
     8821 aacaaaaaaa tcccgcaacc cctgatttca caggatttgc gggagttttt gattagtctt
     8881 tgttcaagtc gcgaagcaat tcatcgatat ggttgccata gacaactgat tcatcaagtt
     8941 caaagaacaa ttcaggtgtc ttataaatac ttagattgtg ccctaactct cgacgaatca
     9001 atcctgatgc tttattcaat ccatcttgtg ctgttttctt atctgatgct aagtcagata
     9061 aaatgctgta atagatcgtt gcttgctgta agtcccccgt aactttcaca tctgtgatcg
     9121 ttacgttctc cacacgaggg tcacggacct ttttgcgcaa aatatcattg acttctttta
     9181 agatttcttg accgactcgg cggtcacggt agttagccat aatgattggc ctccttttat
     9241 cagtttttag tcatttttga cttcttccat gataaatcct tcaattacgt catctacttt
     9301 gatgtcattg aatttttcaa tcattgcacc acattcataa cccattttga cttctttcac
     9361 gtcatctttg aatcgtttca gacttgcaag ttggccttca tagattacga ttccgtcacg
     9421 gattacacgg acaccgctat ctctacgaat atatccttct gttacatagg cacctgcaat
     9481 cgtaccaact ttagaaactt tgaaggtttc acgaacgatc atttgaccgg tgattttttc
     9541 ttcaaattca gggtctagca tccctttcat cgcagtttcg atttcttcga tggctttata
     9601 gatgatacgg tgaagacgaa tatcgacttc ttcagtatca gcttgcactt ttgcctgcgg
     9661 tgtaggacga acgttgaaac cgatgataat agcgttgctg gctgctgcta aggttacatc
     9721 actttcattg attgctccga cagctgaatg gacgattttt acacggacac cttccacatc
     9781 aatcttcttc aatgatgcag ccagtgcttc tgctgaacct tgtacatctg ctttgatgat
     9841 tacgttaact tctttcaatt cgccttcttt caggctttca aataagttat ccaaagtcac
     9901 acggcttgtg gcagcacggt tttctaataa tgcacgtttc gcgcgttctt cacccgctgc
     9961 acgtgctgtc ttttcgtctt cgaagactac gaaacggtca cctgcttgag gtacatcatt
    10021 caagccagtg atttctactg gcgttgcagg tcctgcttct ttatcgcgac ggccaagatc
    10081 gtttgtcatt acacggacac gtccgtaagt attaccgaca acgattgggt caccaacatg
    10141 aagtgttcct tcttggacaa gtaaggttga cacaggacct ttacctttat caagacgtgc
    10201 ttcgatcact gttccgattg cgcgttgtgt tggatctgct tttaaatctt ctacttctgc
    10261 gactaacagg atcatttcca gcaattcttc gatgttttgg ccgaatttcg ctgagatctc
    10321 aacaaagatc gtttctccac cccatgcttc aggaattaac tcatactcac ttaattcttg
    10381 cataacatgt tgagggtttg cacctggttt atcaatttta tttacagcga cgatgattgg
    10441 aacgcctgca gctttggcat ggttgattgc ttcaactgtt tgtggcatga cgccatcatc
    10501 tgcagcaaca actaagatcg tgatatctgt gatacttgct ccacgtgcac gcatacttgt
    10561 aaaggccgca tgtcctggtg tatccaagaa agtgattggt ttaccatcaa tatcgatctg
    10621 gtaggcaccg atatgctgtg tgattccgcc ggcttcgccg cttgttacac gtgaatggcg
    10681 taatgtatcc aataaagttg ttttcccatg gtctacgtgt cccataatcg ttacgactgg
    10741 cggacgtgag actaatttat ctggatcgac ttcttctgcc tcgaagaatt tatcgatatc
    10801 agcaatgtca acttggactt tttcttgtgg ttccatgcca tagtccgtcg ctaacagttc
    10861 aatcgtatct ttatccagtg cttggttttg attgaccatg acaccaagca taaataattt
    10921 tttaatgatt tctgctggct cacgatgaat ttttttcgca atatctgcta cgttcatacc
    10981 ttcagtatac tctaatacat ctggcaattc acggaatttg cgtggtggta cagctggttt
    11041 agttgattgt tgctgtttgc cttttttacc ttttttatta taacgattac ggttattatt
    11101 attaaatttg ccgcgattgt tattgtttgg tttgttgtta ttgttagtac ggttttgatt
    11161 gccgccttgg ctcgttcctt gacgattttg gctgctggta tttcccgtat tattttggtt
    11221 tgttgttggt ttttttcctt gattcacttg accgctccct tgaccgcgat cttgataact
    11281 gcggttattt ttattttttt gttgattgtt cgttgtttct tttttacgtt gatcgttcgg
    11341 ctgttgattg gctggttttc tgcttgcttg ttgtgcagct tgttgtttcg tgcttgggtt
    11401 tttgaacgct tgttgcaatt tcttctcatc attgctagta atcgcaccca tatggttttt
    11461 cacatcgatg ccaagttgtt gtgctttttc cacgacgtct ttactagatt ttttgagttc
    11521 ttttgctaat tcatagattc ttttgttgcc catgcaatca ccttcctaac cttcaattag
    11581 ctccttggtc ttcttcgcaa atccggcatc cattattccg aataccttgc gaggttttcc
    11641 gatcatctgc gtgatttctg cttcagaaaa tagctcaaag caaggaactt cataatatga
    11701 actcttatct tttatctttt ttcttgtatt ctcgcttgca tcggttgcca caaacaccaa
    11761 ttttgctttt tgtttgcgga tttcagcaat ggtcagttct tcacccgtga ttagttttcc
    11821 cgcgcgcatc gctagaccga tgagattcat ggctttttgc cgattaactg tattcatttt
    11881 ccaaataact ctttacgtgc tttttggtga gtgacatagt caagaagttc ttgataaaac
    11941 tcatctgtta atgttgtttc gagtactcga tcgagaattt ttttatccca agcttgttgt
    12001 acttcttccg gctcaagtga gacatacgct cctcgtccag gcatttttcc agttggatcg
    12061 atcgatactt ccccttcttt tgaacgggtg attcggacca tctctttttt aggtttcatt
    12121 tcacctgaaa ccacggattt gcgtaaagga attttccttt gtttcatctc tttgcctcct
    12181 tactaaagtt aagcttctgg tttttcttcg accgtttcat tgttgaatgc aattgtttca
    12241 tattcatcgt ctgttaaatc tgactgaacg attgcttcat catgcagttc ttctgtttct
    12301 ttttgttgtt cttgattttc ataaaattcc gtcatgtcag attctgattt gatatcgatt
    12361 ttatggttag tcaatttagc agctaaacgt gcgttttgtc cgcgtttacc gattgctagc
    12421 gataattggt agtctggaac gacaactgtg caggcctttg gatttgtctc atcgaagatc
    12481 acatccatga cttgtgcagg attcaatgca tttgcaatga atacagctgg atcttcattc
    12541 cattcgacga tatccatgtt ttcgcctttt aattcattga cgattgcttg aactcgttgt
    12601 ccctttggcc cgacacatgt accgactgca tcgatatttg gatcatttga gcgaactgcc
    12661 acttttgaac gatcgccagc ttcacgggcg atgctgacaa tttcaacgat tccatcatag
    12721 acttctggta cttcttgctc aaataagcgg cgcaataggt ctggatggct gcggctaaca
    12781 aatacttgcg gacctttaga cgtattttct actcgggaaa cataaacttt gattcgatca
    12841 tgtggttgat aaaattcatt tggcatttga tcttgtttag aaagaactgc ctcaatttta
    12901 ccaagattga cataaatata acgtttatcc tggcgttcga cgattccttg catgatgtct
    12961 ttttcataag cactgaattc gttataaata atcgttcttt ctgcttcacg tacacgctgt
    13021 aaaataactt gtttagccgt ttgcgcagcg atccgcccaa aatcttttgg tgttacttca
    13081 aaacggatcg tatcaccgat ctcatatgct ggattgatta aaagtgcatc tttcaatgag
    13141 acttccaact gtgaatccat cacttcttcc gttacttctt ttaccgcata gacatggatc
    13201 tttccttttt tctgatcaaa ttccacttcg acgttttgtg cttggccata gtgacgtttg
    13261 tatgcagaaa ccaatgctgc ttctaaagca tcgatcacga tttcttttga gatccctttt
    13321 tcagcttcta aagcgtctaa cgcatttaac atttctttac tcattttttc tgattcctct
    13381 ccgtgattaa aattggatag ctaagcgagc ttttgcaata ttttttcggt caaaagtcaa
    13441 ttctttttct cgtgttttta tgcgtatttt caatgtaagc tgttcagcat caaatgattg
    13501 aagaaatcct tcatattgtt tttcgccatc tactggttgg tataaggaga catggacata
    13561 atcaccaagt gccttttcat agtcgctttc ttttttcaat ggccgctctg ctcccgggga
    13621 ggatacctcc aggaaataag cttgaggaat cggatctgga tctgctgcat caagtttttc
    13681 actcagtttc tcactgacaa aggcgcattc ttcgatatcg ataccgcctt ctttgtcaat
    13741 aaatactcgt aagaaccagc tttttccttc ttttacaaat tcgacttcga caagttcaaa
    13801 attttgttca tctaaaatcg gtgtcaccat ttctgtgact gtttcaacga cgctactcaa
    13861 aagtttcgcc tccttaaaaa attaagtgcg taattccatt aaaaagagtg agcgaaaaat
    13921 ccgctcactc acagttagta tcattaccta taagaactat accatactct gcttaaaatt
    13981 acaagcagac aggaaaacag atgcttatag catatcgaat aacgataatt gattttcatc
    14041 tggtagatct ttcaatacgc cattgtcgtt catatattcg atcaatgttt ttgaaacttt
    14101 accgcgggtg gcaagatctt ctttggataa aaatggaccg tcttttcttg cttcaacgat
    14161 ttgttttgcc acgttggttc ccaaacttgg gacagctcta aatggtgcga tcaacgtatc
    14221 accttcaata acaaagttaa cggcatccga tttatacaaa tcaatcattc caaatttgaa
    14281 tcctcgttcc agcatttcat tggctaactc cagcactgtc agttgattct tttcttttac
    14341 ggaagcatct aatcctttgt ccgtgatttc tttcattgct tgtttcacag catcttttcc
    14401 tttgcacatg gagactagat caaagtcgtc tgcacgtaca gaaaagtatg cacagtaata
    14461 caaaataggg aaataaacct tgaaataagc gacacgaaga gccatcaata cgtaagctgc
    14521 agcatgggct ttcggaaaca tatatttgat ttttgaacaa gaatcgatat accagtcggg
    14581 cacattattt tctttcatcg ccgatagata ggtttctcgc aattcatcag ggatcttgtt
    14641 ccattgtcct ttacgaacag tttccatgat tttaaatgcc atcccgctat ctaatccagc
    14701 atggatcaaa taaaccataa tatcatcacg acagccgatt acttccgcca gtgtcgcatc
    14761 tcctcgtcga atcaattctt ccgcatttcc taaccatacg tctgtaccat gagatagtcc
    14821 ggaaatttgc agtagttctg caaaagttgt aggatgcgtt tcttctagca tccctcgaac
    14881 aaaacgagtg ccgaattctg gaatacctaa tgtccctgtt ttggaataaa tttgttcctg
    14941 acttactcca agtacttcag gaccggcaaa tatccgcatc acttccgggt catccgtagg
    15001 gatcgtttgt ggatcgatcc ctgataaatc ttgaagcatc cgaataacag ttgggtcatc
    15061 atgccctaga atatctaatt tcaatacatt atcgtgaatc gagtgaaaat caaaatgagt
    15121 cgttttccat tccgaatttt gatcgtctgc tggatattgg atcggcgtaa aatcatagac
    15181 atccatataa tcgggaataa cgatgatccc ccctggatgc tggccggttg tccgtttgac
    15241 tccagtagcg ccttttgcta atctgtcgac ttctgcactt cgaaactgca gattattgtc
    15301 cctttcgtat ccttttacat agccatatgc tgttttgtcg gcgactgtac caatcgttcc
    15361 ggcacggtaa acatagtctt cgccaaacaa tactttcgta tagttatggg cttctgcttg
    15421 ataatcacct gagaagttca aatcaatatc gggcactttg tctccatgga atcctaaaaa
    15481 tgtctcaaat ggaatatcat gaccgtcttt gtttaagcgt gcaccacatt ttggacattg
    15541 tttttctggc atgtcaaatc cagaaccata cgtaccatct tcaaaaaact cggaatattg
    15601 gcactctgga caataataat gaggggctaa cggattaact tcagtgattc ctgtcatcgt
    15661 cgcaacaaag ctagagccaa cagagccacg tgaacctact agatagccat cttcattact
    15721 tttatgcact agtttttggg cgatcagata aataaccgag aagccattac cattaataga
    15781 attcaactct ttttttaatc gtttttgaat gatctcaggt aacggatctc cgtacatttg
    15841 ttttgctttt gtgtaactca attctgatat ttcatcttct gaacctggaa tcttcggtgt
    15901 ataaagttca tctttgactg gaatcacttc ttcgcagata tctgcgattt tattcgtatt
    15961 ttctactacg atctctttcg ctgtttcttc ccctaaaaag tgaaatgcag ttagcatctc
    16021 atcggttgtt cggaaatgga catccggcaa actatgacga ttcaacggat tcgctccgcc
    16081 catagaattg atcaaaattt ttcggtaaat ggcatcttct tcgttcagat aatgtacatt
    16141 acctgttgca acaacgattt tatccaaact ttttccgatt tctaccaaat tttggataat
    16201 ttcttccaaa tcatgttcat tttttaccaa ttcttgctcg atcaaaggcg catagaccgc
    16261 ttttggcata acttcaatat aatcgtagaa ttttgctcgg tttcttgcct cttctacccc
    16321 tttttgcatc atggcttcga atatttctcc cttatcacaa gctgagccga tcaatagatt
    16381 ttcacgcatc tttttcaatt gggagcgtgg tattcgtggg acgcgttcga agtattcgac
    16441 attcgacatt gaaatcagtt tgaacaaatc tttcagtcct gcctgatttt ttgctaaaat
    16501 cgttacatgg aaaggtcgag cccttttgta agaatctcct tctccgatat gctcatttag
    16561 ctgatcatga taaagcatgt tatgattgtc cattgcctct ttcacaaaga tccatgctaa
    16621 gtgaccagtt gcttcagcat catagattgc tcggtgatgc tgttccaagc tgacaccaaa
    16681 ttttttagat aacacaccta atccgaaacg tttgaattga ggatacagat atctagctaa
    16741 ttccaacgta tcaatgactg gattggccgc ttcaggaata ccataccttg cgtagctagt
    16801 attcaagaac cccatatcaa aagccgcgtt gtgggctacc aaaattgtat cttttgaaaa
    16861 ttcaaggaac atccgcaata cttcttcttc cgactttgat cctcgaacca ttccatccgt
    16921 gataccagtc agatctaccg ttgttcgtga caaaggatgt cctggatcga taaattcatc
    16981 aaagctttcg atcacatttc ctttatacat tttgactgcg gctagctcga tgatcgtgtc
    17041 atatactgca gacaatcctg tcgtttccac gtcaaatacg acatatgtgg cttcactcaa
    17101 tgcttcatgt gcatcattat aagcaattgg gacaccatca tctacgacat tcgcttccac
    17161 gccgtataag attttcacac ctgctttttt tccagcacta tgtgcttccg gaaaggcttg
    17221 cgcaccaccg tggtctgtaa tggcgatagc tcggtgtccc catttccctg cttgtgccac
    17281 aagatcagag atgctgtttg ttgcatccat cgtactcata ttgctatgaa catgaagctc
    17341 tactcgtttt tccccttcag gagcataatc tttgcgaggt gtatgtttga cttctatgat
    17401 atcttgcgca ttcatgacca aatcacggac aaacgtatct tcttgaatac ttcctcgtac
    17461 ctttaaccag ctaccgacac tgatcgcatc aaatacttgt tcatcttttt cgccgttcga
    17521 gaattttttg acgataaatg atgaagtata atctgtgatt ttcaaagtca agatcttgcg
    17581 ttttgaacgt agttctctga cttctttgtc gaatacgtac ccctcaagtg tgactcttcg
    17641 ttcttcttca acgatactga tcattggtgt cgttggttca tcggctggaa tatttcgtcc
    17701 tagctggatg tggatgggtc cttcaagagc tggcgattgc tcttttcttt cctttttctt
    17761 ttgttcgtgg acaactagac tttcagctgc ttgcttcata aaggcttctg cctgttcttg
    17821 tttgcgttct tcaaaaagtt tcaatactcg ttccgcttgc tgctcatcca cttctggttc
    17881 gatacgaaat tttgggaatc cgtaactgac gaacaactct tctactaatg gcaagtattg
    17941 ttgcttcaaa taagaaatag ctcctgtact gtcgattggc aagatgactt tacgatcttt
    18001 tatcacaggt acctgcgttt tcaatacttg ctgtgctagt ggtgtatcgc attgctgatt
    18061 ttccaaagct tgggcccagt aatcttgcaa gagctgttca tcgaatgtct ggtcatctgc
    18121 taagatattc agtttgactt gtgcaatatc tttaaaagcg atagtcagat gctgagtcaa
    18181 tgaccgatat agcataatag gcaaaatttt ggaaaaatgc agcgtaaatt cccataaacg
    18241 cgatttacga tggaccacta cactatccat ttcaccagca gtaagcagtg gatgattttt
    18301 ttctgcttcc tctagttgga tttgttccaa cagtttttca aataaatctc gtttttctga
    18361 caaagatata cgccctttct gatgagaaac aatgcaattg atcgcatctt atcctcttct
    18421 ttttcagtac cttttagtat actcgttttt tctgagtttt acattaaaaa attggaactg
    18481 cgattcaaat cgcagttcca attttaaaag cgaatcatca gattgtcaaa aacagctgat
    18541 tcagctattt ttattttctg tgttttaacg cttattattc gccttggttc aagaggattg
    18601 gtaaagtatt caccaattct tctttacgta cttcaaccat ttcgccagtt ttcttgattt
    18661 tcacttctac gattccatcc actgcttttt taccgacagt gattctgatt ggacagccaa
    18721 tcaaatcaga atccgcgaat ttcactcctg cgcgttcatt tctgtcatca accagtactt
    18781 catagccagc ttttgtcatc gcttcttcta gttcattcgt caggtttgtt tggtattcgt
    18841 cttttagatt catttggacg atatgcaaat caaatggcgc aattcctttt ggccagttga
    18901 ttccttgttc atctgaatgt tgttctacga ttgctgataa taaacgactt acaccgatac
    18961 cataacagcc cataatcaca aatttttctc gtccattttc gtctagtaca gttgctccca
    19021 tagattcact gtaacgagtg ccgattttga agatatgtcc gatttcgatt cctcgagtaa
    19081 aggcaagaac accattgttg tctggtgaag gatctccttc ttgtacaaaa cgaagatctt
    19141 cataagaaag tacagtgaaa tcgcgttctg gattcacatt tttatagtgg aatcctgttt
    19201 cgttcgctcc agtaatggca ttcgctaaat cttggacata acggtctgca tatactttta
    19261 cgtcatctga aacaccgact ggtccgacag aaccaaactc agcacctaga tatttttgtg
    19321 cttcttcttc tgttgcttct tctaaaaagt cagcagataa aaagtttttc agttttacgt
    19381 cattgacttc atggtctccg cgtaccaaaa caaggacagg ttgttcatcc gcaatgaaca
    19441 atacagactt gatgattttt tgaggttcaa cagaaaagaa atctgctact tcgtcaattg
    19501 attttacgtt aggtgtagct actttctcca attcaagctg tgtttcatgc gatttttttg
    19561 atacatagta gcttgtagcc atctccaagt ttgcagcata atcactttca gtcgaataac
    19621 agatcgtatc ctccccgatt tctgagatcg ccatgaattc ttttgagtct ttcccgccca
    19681 ttgcgccacc gtctccgata atcgagcgaa attctaagcc acaacgcttg aatacttcgg
    19741 tgtaggcttt ttcgtaatct ttatatgtct cgtccaaact ttcttccgtt gcatggaaag
    19801 aatacgcatc tttcatgata aactctcttc cgcgaagcaa accgaagcga ggtcgttttt
    19861 cgtcacgata tttaggttgg atttgataaa gatttaaagg taatttctta tatgaattga
    19921 tttcattacg catcaaatca gtaaaagttt cttcgtgagt tggtccaagg atcatttttc
    19981 gatcattgcg gtctttgaaa cgatacaagt ttggtccata tgtttcgtaa cgcccggatt
    20041 cttcccaaag ttctgctggc aagatggcag gcatcagcat ttctaccgct ccgatttttt
    20101 caaattcttc ccgcataatg cgtttcagtt tttccaatac acgatttgct aatggcagat
    20161 atgaataaat acccgctgat acttggcgga tatatccagc tcttagcaag atttgatggc
    20221 ttaatacttc tgcatcattt ggaacttcgc gtaatgttgg aatcaacatt tttgattgtc
    20281 tcattctata tactccttta tttcctcaaa atagttatcg tttgttatta taccctattt
    20341 gtcaactttt tctagaaaaa gaatcgttga atatcgttcc atgtaactag caccatcaac
    20401 aacattaaaa atccaaagcc agctaatgtc aatattcctt ctttttcttg acttaatggt
    20461 ttcccgcgaa tcccttcaaa aatattcaag actaatttcc cgccatctaa ggcaggaatc
    20521 ggaagcagat tgacgattcc gagattcatt gaaagaagcg ccatcaaact aataacagtt
    20581 gttacacctt gatttgctgc ttctgaagac aattggtaca tcatgacagg tccgcctaat
    20641 ttatctaaac tgaaacctgt aaatagtgat cctaaggctt tgaaaatttc caatgaaccg
    20701 ctgaaagctt gacgcgtccc tccaatgatc ttatccataa aacctgtatt cattggggct
    20761 tttataccaa gttggccaac tttttcgcca tttgactcta cagatttcgg tgtcacgtcg
    20821 acagattgca cctgaccttc tcgttcgatc ttaaagtcta atgttttatc cggatttttc
    20881 gtaatgactg ttgtcagatc attccatgaa tggatttctt ttccgtccac actgactacc
    20941 tcatcatttt cttttaagcc tgcttctgcc gcagctccat taggcatgat ctctcctacg
    21001 cgattagtgt tcgtcacttg aacaccacct tgcataaatg ccagaatgat gaataacagg
    21061 attgccaaaa taaagttatt catgggtcca gcaaagttgg tcagcatacg ctgccacaat
    21121 ttagccgatt ggaactgtac gtcttttggc gcaattctga tttctgttcc gtcgttttca
    21181 ataatcgtcg catcgtgatc aacagggtag gttactactt ctgtttcgtc tccattcaca
    21241 taaccagtga tagtcagctc atcttctaaa tcataacggc tcaattccat cgggatagca
    21301 tttgtcaatt ggattttctt acttaaattt atcttctcta cgatgccgtc agaatttagt
    21361 aaaagagaaa gaggcattcc tggtgccatt tctgtttcat catccccatt gcctgccatt
    21421 cgaacataac cgccaatagg taataggcga agcgtatatg ttgtcccgtc ttttgcttga
    21481 tgcccataaa ttttcggacc cataccgata gcaaattcgc gaacgaggat tcctgatcgt
    21541 ttcgcaaaga agaaatgacc aaactcatga acaatcacta atataccaaa aacgatgata
    21601 aatgtcagaa tcgttttcat agcttttttc tcctttactt gttttttgtg ttttttataa
    21661 aacaacgata aaacactata attttaccat agtataccaa agacaccaat agtatcaata
    21721 taatgaaaaa taaaaacctg cgtcttttat gaaattcaca aagaaacgca ggtatactta
    21781 ctaaataatg ccaaataaat gcatgatagg aaatacaaac agcaaactgt cgaaacggtc
    21841 taagattcca ccatggcctg gtaagatatt tcccgagtct ttcacatcat aatgacgttt
    21901 gattgcagat tcgaccaaat caccaaattg tccgactgct gaaaaaataa tcgtcatcag
    21961 aagcatgaca aacataccat gattaaatag ttcttttgct gggtatagca ataaataaag
    22021 aaatgcgact acaacagcac taccaatacc accgagcgca ccttcaatcg ttttgttggg
    22081 cgaaatatca ggacttaact tatgctgacc ataacgtcga ccaaccatat atgctccgat
    22141 atcagttgcc caaacaataa atagaccaaa tatcaaaaca gccaagcttt ctgttcgtgc
    22201 attgacaaaa ttctggaaac ctattcccac atacaagctg acaagcacag gaaaacctgc
    22261 ttcatcaatc gtatacgtat ttttagaaat aactgatgtt cctaaaagaa tcataactat
    22321 aagataaaat aacataaatg tacttacatt ctctggaaga aagaaaaacc atctttcttt
    22381 tggcaaaaca agtaacactg caccaacggc ggataaaact ccttcaaaac ttaagagtgt
    22441 caatcctttc atccgaaaca gctcgtaaac tcctattact gctaagattg ctgctgtaag
    22501 ctcaaccgct atgcctccga tccatataat cggaataaac aagactagcg ccacggctgc
    22561 tgtgaccaca cgttgtttca tgactgatcc cctttctcat cttctgtttt ttttacaccg
    22621 ccgaatcgac ggtctcgatt ttgataagag gcgattgctt cttcaagatg cgcaccatca
    22681 aaatcaggcc aaagcgcttt tgtaaaatac agctcactat atgcgatctg ccataacaga
    22741 aaattactaa ttcgctcttc tccacttgta cggatcatca gctcaggatc ttgtaactct
    22801 ttaggcaaga aacctgtcat taaatgctta gcaatcaatt catcatcgat ttcttctgcg
    22861 tgtatttctc cttttgctac ttcttcggca atttcttgga cagcagtcac gatctctgct
    22921 ctgcttccat aattcaaagc aaaattcaat accattccag tattgttttt tgtttgctca
    22981 attgcacgtc ttacagcatc ttgcgtatgt tctggcaata cgttttcata acccatgaca
    23041 tgaactttga cattttcttt aatcaattct ggtacgaacg tatcaaagaa gtcgacaggt
    23101 agttgcatga gaaaacttac ttcatctttt ggtcgcttcc agttttcagt cgaaaaggca
    23161 taaagcgtca acactttcac tccaagcctt gatgcttttt ttgtgacttt ctttactgtt
    23221 tccatgcctt ctttatggcc agcaactcgt ggcaaacgac ggttttgcgc ccaacgacca
    23281 ttgccgtcca tgatgatggc aatgtgctga ggaattggtc catcggtatt aaattgaaat
    23341 tcgctttttt cttgaatata tttgtttttt tgcggaaaaa aacgtaacat tctttttcct
    23401 cctatactta aaagattccc actatcttaa gtattatagc aatatctaac tgtttttcct
    23461 atgaaatcat tgttttttta tttaaaaact gaataatttt ttcttttttt aatttttaaa
    23521 taaaagaaat ataaataaaa acagaggaag cggaatgatc cgcccctctg tttttatgat
    23581 tttattaaac ttccaataat tctttttctt tatcagcagc gatcttatct acttctttga
    23641 tgctgttatc tgtcaatgtt tgtacgtctt tttctaatcc gcgcaaatca tcttcggtaa
    23701 tatcaccatt tttttgttgt tttttatatt catcgatcgc atcacgacgg atgttacgaa
    23761 tcgcgatttt tgcattttct gcttcttttt taacatcttt agctaattct tttctgcgtt
    23821 cttctgtcag ttgcgggata actaagcgaa tgacatttcc atcattggtt ggactgattc
    23881 cgatatcact tgccataata gctttttcaa catcttgaag aatgctcttg tcaaaaggtg
    23941 tgatcattaa aacacgtgct tctggaattt ggattgatgc catttggttc aatggtgttg
    24001 gcgcaccgta gtagttcaca gtaatacggt ccaaaaggct agcgttcgca cggcctgcgc
    24061 ggatttgccc aagttcacgt tgaagatttt gtgctgcttt tttcattttt tcttttgctt
    24121 ctgtcataat tgcatctgcc atttttattt cccccttaca gttgttccga tattttcgcc
    24181 taagattgca cggcgaatat ttccgtgttc atttaaattg aagacaagca gtggaatatc
    24241 attatccatg cttagtgaac ttgcagttga atccatgact tgtaatcctt tggcaataac
    24301 ttccagatga gtcagttctt caaattttac tgcatttgca tctactttcg gatcagcaga
    24361 ataaacaccg tctacattgt ttttagccat caggataaca tctgcgccga tttctgccgc
    24421 gcgtaatgct gctgttgtgt ctgtcgagaa gtacgggttg ccggtaccgc ctgcaaagat
    24481 aacgatccgt cctttttcta aatgacgttc tgctttacgg cgaatatatg gctctgcgat
    24541 ttgacgcatt tcaatcgaag tttgcacgcg tgtcggtaca cccacgtttt ccaacgtatc
    24601 ctgtaaagct aaggcattca taactgtagc taacataccc atgtaatcag cttgagcacg
    24661 ttccatgccc atttgtgctc cgatttgtcc gcgccagata tttccgccgc ccacaacgat
    24721 tgccatttca acgcccagct cgtgaacttc tttgatttct tggatgattt ctttgattac
    24781 tggtggtttg attccaaatc ctgcgtcccc agctaaagct tctccactca attttaagac
    24841 tacacgctga tatttcggtg tgaccatgtt cattcctcca atattttcta ttgccatttt
    24901 accatactta gatgatttcg acactctaag actggttttt cttgttttgc ttaaaaaaag
    24961 ggagcgcaca aaccgtgcgt tcccgtctgt tattcaacag aattattttt tcacttggct
    25021 cataacttct tctacaaagt tatcttcgcg tttttcgata ccttcgccaa cttcgaaacg
    25081 tacgaatgtt ttaacagttg cgccttttga tgcaacgtat ttttcaacag tcatatcagg
    25141 atctttaacg aatggttggt ccaccaaagc gatttctgct ttgaatttct tcaagcgtcc
    25201 ttctaccatt ttttcaacga tattcgctgg tttgccttcg ttcaatgctt gttctgtaag
    25261 aacagttttt tcatgttcta attcagcttc tggaatttgt gattcgttta cataacgagg
    25321 attgatagct gctacgtgca tagctacgtc tcttgcaact gtttcgtcag ttgttccatc
    25381 tagaacagtc aatacggcaa tacgtccgcc catatgcaag tatccaccaa atgcagcatt
    25441 gtcgtctttt tctacaactt caaagcgacg gaagctgatt ttttctccga taacttgagt
    25501 tgcttcgatc aagtcagatt caattgtacc tttatctgtt ttgattttca ttgcagcttc
    25561 catgtctgct ggtttgtttt cagcaacaag ttctgcaatt tcttttacta aatcttggaa
    25621 catttcgttt ttagaaacaa agtctgtttc tgagtttact tcaacgattg ctgcagtgtt
    25681 acctttcaca gcaactgaag ccaatccttc agctgcaatg cggtcatttt tcttcgcagc
    25741 ctttgccatt cctttttcac gtaaaagatc aactgctttt tccatgtcgc cttctacttc
    25801 aactaatgct tttttcgcat ccatcattcc tacgccagtc atttcgcgta gttcttttac
    25861 cattttagct gtaacgtctg ccatgtttaa ctcctcctgt gtgtttttct ttttaaaaaa
    25921 agctgcttca aaggagagtg aggcttgtcg cccagccttt gaaacagctc catcattcaa
    25981 aattattctg ctgaagaatt gtcgccttca acaacatcta cgatttcttc gattgatgtt
    26041 gctgtgtttt cttctgtgaa atcttcttca actacttgat cttcaccttg gtttccttcg
    26101 atgaaagcat cagccatttt tgaagtaatc aatttaacgg cacgaattgc atcgtcgttt
    26161 gaagggatta ctacgtcgat ttcatctgga tcgcagtttg tatcaaccat agctacgatt
    26221 gggatattta atttgtgtgc ttcttgaaca gcaatacgtt ctttacgtgg gtcaacgatg
    26281 tacattacat ctgggattct tggcatatca gcgataccgc ctaagaattt ttcaagacgt
    26341 tcacgttctt tgttcaaacc agcaacttct tttttaggta gaacttcaaa agttccatct
    26401 tcttccattg cattgatttg tttcaaacgg ctgatacgtt tttggatagt atcccagttt
    26461 gtcaatgttc cgcctaacca acgatggtta acgaagtatt gtcctgcacg agttgcttct
    26521 tctttgattg cttcttgtgc ttgttttttt gtacctacga ataatgctac gccgccttct
    26581 tcagcaacgc tcttcatgta atcataagct gcatctacta atttaactgt tttttgcaag
    26641 tcaatgatgt agattccgtt tctttctgtg aagatatatt tcttcatttt tggattccag
    26701 cgacgagttt ggtgaccaaa gtgtacgccg gcttctagta attgtttcat agaaattact
    26761 gccatgtttg tttcctccga tttggtttta tttttcctct tcttatcttc taccttgccg
    26821 gcaaactttt tcaagcacct accgacaatc caataagaat gtggatttgc tgatgcataa
    26881 agcaccctca gctattatac agacaaaaga tccgtatcgc aagagcaaat atacttttct
    26941 gctcaacatt caatagttta cctgaaagat aaaaagaatt caagaaaaac agtagatttc
    27001 tctttgtttc tttattatcc tttttccata aaataatttt aggtataaaa gacgaatatt
    27061 attgggcaat ccttcttttt tttgttatga tacatgtgaa atctttcgta aaggagaaag
    27121 aaaatgcgca aagctcaaag acatttgctg attaaacaag tcattgaaga attcccgatc
    27181 cgtacgcaag aagaactatt aaacaaactt gggcattatg gcgttaccgc cacgcaggca
    27241 acgatttctc gagatatccg tgatctaaaa atcgtgaagg cacctgatga aaatggcgtt
    27301 tcccgcttcg tattgtttcg cgaaaaagga actcctgaga ctaggactga ggaagaggat
    27361 cggctggttc aaatgattga agacattgta ttgaaagtcg aacgagtcca ctttttgacg
    27421 atcgtcaata ccttgccaga caatgctcat ttatttgcat ctgttttaga tgagatcaaa
    27481 cctccctcta ttgtcagtac aattgctgga ttcgatacga tcatggtcat ctcggaaaat
    27541 gaggaggacg caaaacgagt agaagaattt cttcaccatc caactgaagt atcacttttt
    27601 taatcagagc acgtattcct aatatggaat gcgtgttttt ttattttcaa tattttcctt
    27661 attgaataaa cctttacact ctttacaaaa atacatcatt ttttattcaa atttttcaac
    27721 accttgattg aatcacaata atcatcattt atattggatg ttaacaagag cagcttcttg
    27781 ctctttgtgt atttcaaaaa agaaatgaaa ggaaatcata tgtataaatt attaacttct
    27841 ggaccattga cgacttctga aacagtgaaa aatgctatgc tgatcgatca ttgtacttgg
    27901 gatcaagaat acaaagaaat tacacaatgg ataagaaaaa aattattgga tcttgctcaa
    27961 gtatcggaag gaatatacac aacggtctta atgcaaggta gcagctcctt cggggtagaa
    28021 tcggtattaa gttctgtgat caggccagaa gatactgtac tgatttgttc aaacggcgca
    28081 tatagacaac gaatgatcaa catgtgcgaa tgtctgaaac tgaactatac cgtttatgag
    28141 gtatcggaac atcaaatcct ccaagctcat gtgattacac agctgattga agagaatccg
    28201 tctatctccg cactagcaat ggtccatagc gagactactt ccggtatttt gaataatttg
    28261 gaagagattg ctgctgtcac acaagaaaga gatcttttgt ttatagtgga cgcgatgtca
    28321 agctttggtg ggataccgat ttgtgtagcc gaactaggga ttgatttttt gatttccagc
    28381 tcaaacaaat gtattcaagg tgttccaggc ttttcttttg tacttgctaa taaagcggaa
    28441 ctggaaaaac gaaaaaatgt tagccgaagt ttgtcacttg atctatatga ccagtaccgc
    28501 gtgatggaaa acgagaatgg caaatggcgt ttcacttccc ctacccatac ggttttggct
    28561 tttcaacaag cgctgaagga actagaggca gaaggaggaa tcgaaactcg atattcacgt
    28621 tatctcgcca ataatcatgt gctacgacaa aaaatgacag agatggggtt ccagcctttc
    28681 attcaagaat atcaggggcc attcatcacc tcttttcttt accctaagga ctggcgattt
    28741 gattttaatc atttttatca gtatttaaag caaaatggat ttgtgatcta tcccgggaaa
    28801 atcagcgatc atgaatgttt tcgtatcgga aatattggcg agatctatcc ggaagatatt
    28861 ttggaactga cagcaattat caaagactat aaggagaacg ttaatgatta aaactgtaat
    28921 ttttgattgg gcaggaacaa ctgtggactt tggctgtatg gctcctgtcc acgcttttag
    28981 aaatgctttt ctagaaaaag gaatccaact gactgacaaa gaaatccgct aaccgatggg
    29041 aaaattaaaa tgggatcata tccaacagct tctttccctc ccttctgtca aaaaacaatg
    29101 gatagctatt tatggacaac tacctcagga aaaagaggtg gaggaattgt atcaacaatt
    29161 tgaacattat ctgtttaaag atttggtcaa gcattctacc ttgaaacccg acacattgga
    29221 aacgatcgaa cggttgagaa acgctgggat caatattggt tccacgaatg gatttaatgc
    29281 tcctatgatg acaatcgtag cagaaaccgc aaaaaaagaa aggtattcac cagacttcat
    29341 ggcaactttt gaagacgtcg aagggtatgg tcgaccgttt ccttatatga tccataaaaa
    29401 catgcagtac ttcaaaaaca agtcggttga tgaagtaatc aaagtcggag atacggtctc
    29461 agatatccag gaagggaaaa atgccggagt gttgacagta ggtgtaattg aaggtagttc
    29521 gctaatgggg atttcttatg atgagtacca aaaattagag atggggaaaa agatcgttta
    29581 aaacagtctg ttgctcttag attccaacaa gccggcgctg atatttgtgt aaacaattta
    29641 aaagagttaa cagaatacat tttgtacgct gacatgaatc cagaatgact tttatacaaa
    29701 ataagaggtt gtgaaaaagc tgtcctgtat caagtaataa aaacagccaa gcaaaaatag
    29761 ctcctcatat ttttcgtttg gttaggctta ttaccgcaga tgcaagcttt tgaacaccgt
    29821 ttattcgaaa aaaaaaaggg agctgtgaca cgacttttgt cacagtcccc ttatttgcaa
    29881 acaaacagtg tttaagagac aacctctcca ctaaacggtg ttcattcagc tgactctcgg
    29941 tatttgctca aaaaacgata aaatttgaaa agctattttc tcttttgttt ctctaatact
    30001 cggatcagaa cgctgatttc acattctctt tttcttacat cttatctggt gcatgaagtc
    30061 ctagcaaacg aaggtcttct ttcaataata cagtcactgc ataaactaga gctaagcgtg
    30121 cttctttttg ttcatcatca gctaaaatct tcgtatgagc atagtatttg ttgaatgctt
    30181 gtgctaattt gattgcatgt ttcgcaatca ctgacggttc gtatttttcc ccagcagaca
    30241 agaccgtttc agggtatttt tgaactaatt taaccacttc ccagctggta tcgtcattca
    30301 atgcatagtc tgctgtttct gaagggacaa atcctgcttt ttccaacagg ctgactgcac
    30361 gagcatgtgt atattgcaca taaggtccag tttctccttc aaatcgaaca acttcttcca
    30421 ggttaaagtc aaatgtattc agtcgatcgt ttttcaaatc gtggaaaatg actgccccaa
    30481 ccccaacttg tttagctaca gcatctttgt tttccaaatc agggtttttc tcgctgattt
    30541 gttctttagc agattggatt gcttcattta atacttcttc taataagacg atctttcctt
    30601 tacgagttga taatttttta ccaccttgcg tgatcaaacc aaatggaata tggtgcatgt
    30661 cgtcagacca gtcaaagccc atttccttca agacagcttt caactgttta aaatgatagc
    30721 tttgttcatt ccctactaca tatagagatt gtttgaagtc gtaagtacgt ttacggtaca
    30781 atgcagcagc taagtcacgt gtaatgtata gtgtcgcacc gtctgacttc ttaatcaacg
    30841 ctggattcag gtcataagca gataggtcaa cgatctctgc acctttatcc tcgttcagca
    30901 aatgtttttc ttctaaaagt ttgacgattt catccatctt gtcattgtag aaagcttcac
    30961 cgttcaacga atcgaaacgt acttccagca gatcatagat tttattgaat tctttcatcg
    31021 attcatcacg gaaccattgc cataattgaa tagcctcttt atcgccttct tccagacgtt
    31081 tgaaccaagc acgagcttct tcatttaatt ctggttctgt ttcagctact tcatggaatt
    31141 ggacgtataa acgaagcaat tcattgattg gttctgcttt aacagcttct tctgtacccc
    31201 attttttgta agcgacgatc agttttccaa actgtgttcc ccagtcacct aaatggttga
    31261 tgcggattgg ctgataaccg attttttcca taatgaaacc gatcgaatta ccgataactg
    31321 tcgaacgcaa atgtcccatt gagattggtt tggcaatatt aggagaagac atgtcgattg
    31381 gtactgttcc ttgattcccg atgttgctat ccccataatg ttctttttct ttcactactg
    31441 tttgcaaaac ttttttgctg ataagttctt tattcatgaa aaagttcaag taaggtccga
    31501 caacttcgat tttttcaaag ttggcagaat cgattttttc tgctaaatct gcagcgattt
    31561 gctgtggcgc ttttcggtaa acttttgcta atgaaaaggc tggaaatgca acatctccgt
    31621 gttcagctga ttttggattt tctagtaatt gctcgacttg ttccagtgtt aaatcatctt
    31681 tgacagcgtc atagacagct tttgcgacaa gatctttatt attcatcttt attcctccta
    31741 aagtgttccc ttgattgtta aacaaaaaaa atctctagcg acggcatact tagtatgcca
    31801 tcactagaga cgagatttcc cgcggtacca ctccaattgt cctaaaaaag gaccagctcc
    31861 atctgatatc ggtagacgac cgtctgttta aaacagaatt ctccaagtgc gcttcgttgt
    31921 atcttcttca ttcggcttcc accacttccg aattcgctag ccaagaatga tacaagtact
    31981 ctcttgttca acaaatctta gtcttattaa actttcttga attatatcag aaaaaaaaac
    32041 gaaaggctag tcgtttcata aaaaaacaat ccagatggcc taaaggagaa gaaataccac
    32101 ctggatagct ataaatcatt tcgtaaatac gaaagactta acaaattaat cagctacgat
    32161 aatcgttcct tcttcagaag ctaaaagatt ctcgatattt tctaaagaag tgatgattgc
    32221 cttagcgttt ggttttgctt caacaaatgc aatagctgct tctactttcg gaagcatgct
    32281 tcctggagcg aattgctttt catcaatgta ttgtttcatt tctgaaacag taacagtttc
    32341 taatttcttt tgatctggtt tttggtaatt gacatacaca ttgtctactc ctgtcaatac
    32401 gatcagcaaa tccgcatcga tgatttcggc taatttttct gaagcaaaat ctttatcgat
    32461 tacggcttct cgtccttcta atccagtagc tgtttctaca acaggaatcc caccgccacc
    32521 aacagagact gtgataactc cttgatcgac cagcgtttcg atgacacgtg cttctttaat
    32581 cgagatgggt ttaggggaag cgactacttt tctccatcca cgtccagcat cttctttgaa
    32641 tgtcacagtg gagtcagcat tcatttgttc tttggcttct tcttccgtgt agaatggacc
    32701 gactggttta cttggatttt tgaatgaagg atcattttca tccacaataa cttgagtgac
    32761 taaagaaacc acatctttat cgatcccttt ttccttcagt acttcgccca tggcgttttg
    32821 taaccagtaa ccgatagatc cttctgtcat tgcaacacat gtatctaaag gcattgccgg
    32881 tgttttctca gaatcagcag cttgctgctg aatcaatagg ttaccgactt gcggaccatt
    32941 tccgtgggag atgatcaatt catctccttg ttcgataaat ttcactaaat actttgctgt
    33001 ttccattaac gcttcttgtt gggcttttgc acttgcatcc gtagacaaga tggcattgcc
    33061 ccctaaagcg acaactactt ttcgtttggc catttcattc gtcctttctt cagttctacc
    33121 gaattttcta gataacaaaa cgagccagcg ttttgtgatt ttccctcaat gctgactcgt
    33181 tttttcgtga gatgaatgtg gttatgctta aacgcgaggg ataaacaagt tacctaatgt
    33241 tgctgccatg atcgctttga ttgagtgcat acgattttct gcttggtcaa attgacgagc
    33301 atatttgctg cggaagactt catctgttac ttccatttca gtgatgccaa agcgttcttt
    33361 catttgttca ccgtaaacag tgtttgtatc atggaaagct ggcaagcagt gcaagaagat
    33421 caaacgatct gtgttgtgtg ttttttctac catttccata ttgatttggt aaggtttcaa
    33481 caatttgata cgttcttcga atttatcttc ttcacccatt gatacccata catcagaata
    33541 aaggacgtct gctccgtcta cacctttatc aacatcgtcg gtaatcatca attgtgcacc
    33601 ggatttttca gcaaagcctt ctgccatttt gacgatttct tcttcaggtt gtaattcttt
    33661 tggtgcaacg atacgcatat tcgctcctaa aattgcacct gtgactaata aagagttagc
    33721 catattgttt cgaccatctc cgcagtaagc aacagtgata ccttctactg ttccaaagtt
    33781 ttcttggata gttaaaaagt cagcgatcat ttgtgttgga tgccattcat cagtcaagcc
    33841 attccaaact ggaacaccag agaattctgc tagttcctct accatttttt gactgaatcc
    33901 acggaattcg attccgtcaa acatacgtcc tagtacttta gctgtatctt ctgtggattc
    33961 ttttttacct aattggatat catttgcacc tagatattca ggatgtgcac ctagatcgat
    34021 cgctgcagta gtaaatgcag aacgagtacg tgtagatgtt ttttcaaata aaagcgcaat
    34081 attttttcct tctagatagt gatgtgggat accacgtttt ttcaagtctt tcaagtgttc
    34141 tgaaaaatcg atcaaatatt gtaattcttc ttttgtaaag tctttttctg ctaataagct
    34201 tcttccttgg aatactgatt ctttcatatt aaacattctc ctttagattg tttttattta
    34261 agattaaaga ggaaatcccg acggcagctg acagtaagac tgccgtcagg aaacaaatta
    34321 cttcaagtct tcacggacaa gtggttggct catgcagcgt ggaccaccac gacctcgtga
    34381 caattcactt gaattgattt ctaacacttt gatgccatag ctacgaagca attcgttcga
    34441 tacataattt cggttataag tgactacaac acctggagcg attgccaatg tgtttgatcc
    34501 atcattccat tgttctcgag gtgcaacgat ctcatctcca ttaccagttg ggatcagtac
    34561 aagatcatct aatccaagag cagctttcat cgtttcgtgt aagttatctg aatgagtaat
    34621 cttgatatca tcaccatctg gttcgattgt aaagacatcc atcttaccgt ctttactttg
    34681 aattgctgga tggatagtga atttatcgtg atctaccatt gtaaatacgg tatccaaatg
    34741 catcattgca cggttgttcg gaattttgat tgccaacact ttttcaaatc ctgaattttt
    34801 tgcgaatagg tggcgtgcta atttttctaa agctttcgca ttagttcgtt gagaaatccc
    34861 aacagctact actttatcgc ttaagatcaa ttcgtctccg ccttcgatat gatctggatt
    34921 ttcacgatcc aaccatactt cgattccttt atttgcaaat cttggatgat gtttcaaaat
    34981 atattctgta aacatcgatt cacgacgacg tgcttcaaaa gtcatcttat tgactgtcat
    35041 cccatttccc attgatgcgg aagggtcgcg tgtaaagtac aagtttggca ttgggtccat
    35101 gtaaaatgga tagtcatcgt ctgctgacag atcatataga ctgctagaac gtacttcgat
    35161 atcttttgta cgaaccccag ccatgatttt atctaccatt tcttgcgttt ccattgatag
    35221 aaggaactca tgaagaccct ctcttacagc attcgatgca atatgagatt catccaacat
    35281 tttattcaag aattgttctt tgacattgcc tgcgtcaatc gcttctgccg ctaatttttc
    35341 caagtaaaga gtctcgacgc cttcattttg caatgtcttc gcaaagttgt catgttcttc
    35401 ttgagcaatc ggaagatatg gaatatcatc gaacaacaga cgatccataa tatctggtgt
    35461 caaattttcc acttcttgtc caggccgttt cagtaaaact gtctttaatt tccctatttc
    35521 agagaaaacg tgaataggtt tatccatgtt gtgttgcctc cttctttttg attacatgta
    35581 taggatatcc tccttttgta atcactttca taattttgtc tcattcaaaa tg
//
LOCUS       DARBDN010000018        34397 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000018 DARBDN010000000
VERSION     DARBDN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.018"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            352..1041
                     /locus_tag="SCH06_000934"
     CDS             352..1041
                     /locus_tag="SCH06_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1077531.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="SCH06_000935"
     CDS             1028..2236
                     /locus_tag="SCH06_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1077532.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="SCH06_000936"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="SCH06_000936"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEG1077533.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="SCH06_000937"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="SCH06_000937"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEG1077534.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="SCH06_000938"
     CDS             complement(6339..7034)
                     /locus_tag="SCH06_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEG1077535.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="SCH06_000939"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="SCH06_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEG1077536.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="SCH06_000940"
     CDS             complement(8233..8424)
                     /locus_tag="SCH06_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HEG1077537.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="SCH06_000941"
     CDS             complement(8445..9335)
                     /locus_tag="SCH06_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEG1077538.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="SCH06_000942"
     CDS             complement(9322..10089)
                     /locus_tag="SCH06_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEG1077539.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="SCH06_000943"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="SCH06_000943"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEG1077540.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="SCH06_000944"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="SCH06_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEG1077541.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="SCH06_000945"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="SCH06_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEG1077542.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="SCH06_000946"
     CDS             14660..15043
                     /locus_tag="SCH06_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077543.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="SCH06_000947"
     CDS             complement(15211..15969)
                     /locus_tag="SCH06_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HEG1077544.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="SCH06_000948"
     CDS             complement(15987..16805)
                     /locus_tag="SCH06_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEG1077545.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="SCH06_000949"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="SCH06_000949"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEG1077546.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="SCH06_000950"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="SCH06_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEG1077547.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="SCH06_000951"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="SCH06_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEG1077548.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="SCH06_000952"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="SCH06_000952"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEG1077549.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20824..21066
                     /gene="yaaA"
                     /locus_tag="SCH06_000953"
     CDS             20824..21066
                     /gene="yaaA"
                     /locus_tag="SCH06_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEG1077550.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21053..22177
                     /gene="recF"
                     /locus_tag="SCH06_000954"
     CDS             21053..22177
                     /gene="recF"
                     /locus_tag="SCH06_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEG1077551.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22174..24120
                     /gene="gyrB"
                     /locus_tag="SCH06_000955"
     CDS             22174..24120
                     /gene="gyrB"
                     /locus_tag="SCH06_000955"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEG1077552.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24140..26611
                     /gene="gyrA"
                     /locus_tag="SCH06_000956"
     CDS             24140..26611
                     /gene="gyrA"
                     /locus_tag="SCH06_000956"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEG1077553.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26847..27146
                     /locus_tag="SCH06_000957"
     CDS             26847..27146
                     /locus_tag="SCH06_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEG1077554.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27196..27708
                     /gene="ssb"
                     /locus_tag="SCH06_000958"
     CDS             27196..27708
                     /gene="ssb"
                     /locus_tag="SCH06_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEG1077555.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27734..27970
                     /locus_tag="SCH06_000959"
     CDS             27734..27970
                     /locus_tag="SCH06_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEG1077556.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28113..30086
                     /locus_tag="SCH06_000960"
     CDS             28113..30086
                     /locus_tag="SCH06_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEG1077557.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30092..30544
                     /gene="rplI"
                     /locus_tag="SCH06_000961"
     CDS             30092..30544
                     /gene="rplI"
                     /locus_tag="SCH06_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEG1077558.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30818..32185
                     /gene="dnaB"
                     /locus_tag="SCH06_000962"
     CDS             30818..32185
                     /gene="dnaB"
                     /locus_tag="SCH06_000962"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEG1077559.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32965..34257
                     /locus_tag="SCH06_000963"
     CDS             32965..34257
                     /locus_tag="SCH06_000963"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEG1077560.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10495 a         6692 c         6807 g        10403 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtatattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    20821 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    20881 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    20941 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21001 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21061 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21121 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21181 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21241 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21301 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacagaaaaa
    21361 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21421 agtaaaaggc agcccgcaga ccaggcggaa gtttttagat atggaattag gccagatcaa
    21481 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21541 cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21601 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21661 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21721 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    21781 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    21841 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    21901 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    21961 taaagaagag acaggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22021 tgataatcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22081 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22141 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22201 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22261 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22321 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22381 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22441 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22501 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22561 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22621 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22681 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22741 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    22801 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    22861 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    22921 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    22981 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23041 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23101 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23161 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23221 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23281 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23341 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23401 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23461 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23521 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23581 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23641 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23701 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    23761 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    23821 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    23881 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    23941 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24001 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24061 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24121 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24181 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24241 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24301 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24361 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24421 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24481 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24541 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24601 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24661 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24721 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    24781 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    24841 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    24901 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    24961 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25021 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25081 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25141 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25201 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25261 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25321 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25381 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25441 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25501 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25561 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25621 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25681 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25741 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    25801 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    25861 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    25921 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    25981 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26041 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26101 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26161 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26221 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26281 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26341 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26401 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26461 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26521 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26581 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26641 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26701 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    26761 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    26821 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    26881 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    26941 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27001 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27061 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27121 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27181 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27241 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27301 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27361 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27421 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27481 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27541 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27601 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27661 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27721 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    27781 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    27841 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    27901 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    27961 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28021 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28081 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28141 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28201 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28261 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28321 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28381 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28441 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28501 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28561 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28621 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28681 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28741 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    28801 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    28861 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    28921 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    28981 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29041 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29101 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29161 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29221 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29281 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29341 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29401 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29461 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29521 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29581 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29641 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29701 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    29761 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    29821 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    29881 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    29941 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30001 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30061 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30121 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30181 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30241 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30301 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30361 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30421 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30481 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30541 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30601 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30661 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30721 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    30781 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    30841 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    30901 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    30961 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31021 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31081 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31141 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31201 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31261 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31321 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31381 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31441 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31501 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31561 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31621 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31681 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31741 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    31801 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    31861 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    31921 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    31981 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32041 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32101 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32161 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32221 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32281 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32341 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32401 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32461 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32521 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32581 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32641 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32701 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    32761 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    32821 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    32881 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    32941 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33001 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33061 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33121 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33181 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33241 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33301 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33361 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33421 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33481 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33541 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33601 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33661 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33721 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    33781 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    33841 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    33901 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    33961 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34021 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34081 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34141 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34201 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34261 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34321 gataataata acttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca
    34381 cagtcccttt ttccgaa
//
LOCUS       DARBDN010000019        30591 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000019 DARBDN010000000
VERSION     DARBDN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.019"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            363..731
                     /locus_tag="SCH06_000964"
     CDS             363..731
                     /locus_tag="SCH06_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HEG1077561.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            911..1852
                     /locus_tag="SCH06_000965"
     CDS             911..1852
                     /locus_tag="SCH06_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEG1077562.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1921..2652
                     /locus_tag="SCH06_000966"
     CDS             1921..2652
                     /locus_tag="SCH06_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEG1077563.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2796..4976
                     /locus_tag="SCH06_000967"
     CDS             2796..4976
                     /locus_tag="SCH06_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEG1077564.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4996..5478
                     /locus_tag="SCH06_000968"
     CDS             4996..5478
                     /locus_tag="SCH06_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEG1077565.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5494..6255
                     /locus_tag="SCH06_000969"
     CDS             5494..6255
                     /locus_tag="SCH06_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEG1077566.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6386..7720
                     /locus_tag="SCH06_000970"
     CDS             6386..7720
                     /locus_tag="SCH06_000970"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEG1077567.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            8027..8512
                     /locus_tag="SCH06_000971"
     CDS             8027..8512
                     /locus_tag="SCH06_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HEG1077568.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8505..9188
                     /locus_tag="SCH06_000972"
     CDS             8505..9188
                     /locus_tag="SCH06_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEG1077569.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9314..11959
                     /gene="polA"
                     /locus_tag="SCH06_000973"
     CDS             9314..11959
                     /gene="polA"
                     /locus_tag="SCH06_000973"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEG1077570.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            12004..12840
                     /gene="mutM"
                     /locus_tag="SCH06_000974"
     CDS             12004..12840
                     /gene="mutM"
                     /locus_tag="SCH06_000974"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEG1077571.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12804..13433
                     /locus_tag="SCH06_000975"
     CDS             12804..13433
                     /locus_tag="SCH06_000975"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEG1077572.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            13485..13817
                     /locus_tag="SCH06_000976"
     CDS             13485..13817
                     /locus_tag="SCH06_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEG1077573.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            14129..14620
                     /gene="nrdR"
                     /locus_tag="SCH06_000977"
     CDS             14129..14620
                     /gene="nrdR"
                     /locus_tag="SCH06_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEG1077574.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14643..16016
                     /locus_tag="SCH06_000978"
     CDS             14643..16016
                     /locus_tag="SCH06_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEG1077575.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            16016..16942
                     /gene="dnaI"
                     /locus_tag="SCH06_000979"
     CDS             16016..16942
                     /gene="dnaI"
                     /locus_tag="SCH06_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEG1077576.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            17071..17511
                     /locus_tag="SCH06_000980"
     CDS             17071..17511
                     /locus_tag="SCH06_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEG1077577.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17655..18356
                     /locus_tag="SCH06_000981"
     CDS             17655..18356
                     /locus_tag="SCH06_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEG1077578.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            18353..19474
                     /locus_tag="SCH06_000982"
     CDS             18353..19474
                     /locus_tag="SCH06_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEG1077579.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19489..20721
                     /gene="pepT"
                     /locus_tag="SCH06_000983"
     CDS             19489..20721
                     /gene="pepT"
                     /locus_tag="SCH06_000983"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEG1077580.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20853..21761
                     /locus_tag="SCH06_000984"
     CDS             20853..21761
                     /locus_tag="SCH06_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HEG1077581.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21796..22068
                     /locus_tag="SCH06_000985"
     CDS             21796..22068
                     /locus_tag="SCH06_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEG1077582.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            22079..23125
                     /locus_tag="SCH06_000986"
     CDS             22079..23125
                     /locus_tag="SCH06_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HEG1077583.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23376..25985
                     /gene="clpB"
                     /locus_tag="SCH06_000987"
     CDS             23376..25985
                     /gene="clpB"
                     /locus_tag="SCH06_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HEG1077584.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(26136..26822)
                     /locus_tag="SCH06_000988"
     CDS             complement(26136..26822)
                     /locus_tag="SCH06_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077585.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26800..27294)
                     /locus_tag="SCH06_000989"
     CDS             complement(26800..27294)
                     /locus_tag="SCH06_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEG1077586.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(27314..28534)
                     /locus_tag="SCH06_000990"
     CDS             complement(27314..28534)
                     /locus_tag="SCH06_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1077587.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28681..30516
                     /gene="lepA"
                     /locus_tag="SCH06_000991"
     CDS             28681..30516
                     /gene="lepA"
                     /locus_tag="SCH06_000991"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEG1077588.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT        10250 a         5445 c         6594 g         8302 t
ORIGIN      
        1 agaaagaggt cgtgagcctg ccgtttcact ctgagtcaca aagagcaatt tcaaaaaata
       61 gcttctcatg tttgttgaat attgtgtctt gtgaccgagg agttgtcagg agaacaccgt
      121 ttaccagagg ttgtgacttg tttttagtca cgacctcttt ttttatttat tccatataaa
      181 tacacattat ttattccgaa aagtgaaagc gcaaataaca aaaacaacca acttatttat
      241 tattaaagaa aagcgtattt aagtaggacg attctgttga gagctttcgt agattttccc
      301 attttcctat ggtaaactga caaagttgag aatgttagaa cagatcgttt aggaggaaac
      361 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
      421 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      481 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      541 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      601 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      661 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      721 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      781 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      841 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      901 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      961 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
     1021 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
     1081 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
     1141 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
     1201 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
     1261 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
     1321 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1381 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1441 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1501 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1561 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1621 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1681 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1741 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1801 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1861 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1921 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1981 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     2041 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     2101 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     2161 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     2221 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     2281 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     2341 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2401 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2461 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2521 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2581 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2641 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2701 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2761 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2821 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2881 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2941 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     3001 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     3061 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     3121 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     3181 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     3241 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     3301 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3361 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3421 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3481 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3541 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3601 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3661 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3721 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3781 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3841 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3901 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3961 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     4021 attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa
     4081 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     4141 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     4201 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     4261 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     4321 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4381 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4441 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4501 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4561 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4621 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4681 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4741 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4801 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4861 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4921 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4981 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     5041 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     5101 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     5161 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     5221 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     5281 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     5341 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5401 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5461 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5521 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5581 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5641 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5701 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5761 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc cgataaggct
     5821 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5881 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5941 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     6001 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     6061 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     6121 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     6181 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     6241 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     6301 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6361 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6421 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6481 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6541 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6601 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6661 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6721 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6781 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6841 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6901 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6961 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     7021 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     7081 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     7141 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     7201 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     7261 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     7321 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7381 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7441 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7501 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7561 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7621 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7681 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7741 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7801 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7861 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7921 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7981 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     8041 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     8101 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     8161 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     8221 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     8281 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     8341 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8401 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8461 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8521 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8581 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8641 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8701 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8761 cctactctct tttgaatggc ataatattag cggttactct tgcatactac gatattggaa
     8821 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8881 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8941 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     9001 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     9061 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     9121 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     9181 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     9241 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     9301 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9361 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9421 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9481 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9541 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9601 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9661 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9721 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9781 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9841 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9901 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9961 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
    10021 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
    10081 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
    10141 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
    10201 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
    10261 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
    10321 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10381 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10441 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10501 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10561 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10621 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10681 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10741 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10801 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10861 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10921 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10981 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    11041 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    11101 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    11161 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    11221 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    11281 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    11341 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11401 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11461 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11521 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11581 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11641 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11701 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11761 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11821 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11881 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11941 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    12001 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    12061 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    12121 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    12181 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    12241 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    12301 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12361 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12421 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12481 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12541 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12601 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12661 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12721 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12781 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12841 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12901 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12961 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    13021 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    13081 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    13141 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    13201 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    13261 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    13321 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13381 aaatacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13441 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13501 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13561 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13621 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13681 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13741 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13801 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13861 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13921 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13981 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    14041 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    14101 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    14161 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    14221 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    14281 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    14341 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14401 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14461 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14521 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14581 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14641 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14701 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14761 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14821 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14881 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14941 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    15001 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    15061 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    15121 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    15181 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    15241 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    15301 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15361 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15421 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15481 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15541 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15601 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15661 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15721 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15781 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15841 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15901 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15961 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    16021 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    16081 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    16141 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    16201 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    16261 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    16321 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16381 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16441 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16501 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16561 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16621 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16681 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16741 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16801 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16861 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16921 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16981 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    17041 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    17101 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    17161 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    17221 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    17281 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    17341 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17401 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17461 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17521 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17581 tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta taattatcta
    17641 gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca gtgggtgact
    17701 ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac ttacccgttg
    17761 cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt caaggtcctt
    17821 atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc accgtacgcc
    17881 ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc acgattgcgg
    17941 gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat caacgcttaa
    18001 gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta cgatcttggc
    18061 tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat aaaaaaatat
    18121 atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa atggagctga
    18181 tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa tggacaagag
    18241 agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat caagaggcac
    18301 gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag ccatgacaat
    18361 cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc tagctgaaga
    18421 aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac gagtaatgat
    18481 gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa tcgatttgct
    18541 gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg atcagccaca
    18601 agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag cacacacgaa
    18661 catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg gtattgaagt
    18721 ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg tttatgtacc
    18781 tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg gtacacaagg
    18841 tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc cggaagctgg
    18901 tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg caaaagttga
    18961 ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt cagctcatcc
    19021 ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa tgtttgggtt
    19081 aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag aacaagtaaa
    19141 agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa aatcctctgt
    19201 gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag caatcgccca
    19261 aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg atatgcaaag
    19321 cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca agcaacgatt
    19381 tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact ttttcgtttc
    19441 tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat gtacgaaaat
    19501 cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc aacaagcaaa
    19561 acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa agaattagaa
    19621 gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat gggaacatta
    19681 ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat ggatacagca
    19741 gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg cgagtctacg
    19801 atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc aaatttgaaa
    19861 aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg agcagatgac
    19921 aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa tccttctatc
    19981 cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt cggagcggat
    20041 aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg tggtccttta
    20101 ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat ccaagggaaa
    20161 aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt agcaatcgat
    20221 tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata cgaaggtttc
    20281 ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta tatcattcgc
    20341 gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat ccaagaagag
    20401 ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca atattacaac
    20461 atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca agcaatgatc
    20521 gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg ttcaaaaatc
    20581 tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat gcacggacga
    20641 ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt aaaaattgca
    20701 gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc gttcgtccca
    20761 atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg ttgtcccgcc
    20821 ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt ttttataaca
    20881 aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat tatgtaaaag
    20941 aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt gatgatgcgg
    21001 aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata ggtggagacg
    21061 gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac catgtcggat
    21121 tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc ctcaaaaaag
    21181 aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat ggtcaagtca
    21241 atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca gcagtttgga
    21301 tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag ttttttaagt
    21361 tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag cattggaaag
    21421 gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt acaaattttg
    21481 acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct tccttagata
    21541 ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat acgatccccg
    21601 gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa tctgtgggca
    21661 ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt gtatcaaaag
    21721 gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag ttaacagaaa
    21781 gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta ccttttcatt
    21841 gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag aactagcggc
    21901 tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg tttgggagga
    21961 ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac tataggattc
    22021 gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg agcaggagat
    22081 gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga ttgtgatttt
    22141 tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg aattgctgtc
    22201 taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc aaatcgctga
    22261 agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa cgaaagatgg
    22321 gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta caggaacgct
    22381 gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg gagcaggggt
    22441 gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat tagctggctt
    22501 ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt ttatcatcgc
    22561 tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg tcagcttgaa
    22621 tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc gtttgcggaa
    22681 atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc aaaccattat
    22741 ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac ttgtattttg
    22801 gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt ttctactgac
    22861 catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc ctgctggtat
    22921 tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa cagttgacgc
    22981 agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc tctatggatt
    23041 tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag aagtaaaaaa
    23101 agagaataaa gaaaatcaag ggtaggtctt ttataagatc tacccttttt atcaaatcaa
    23161 agaaaaacgt tatggataag ataattttac gtttgtttgg ctcttttttt atatacatac
    23221 aatcaatttt gtttttttaa gatttatata agtcgagaaa aaaagtcaaa aaactatgtg
    23281 tatattttga ccaaaattga ccaaagcgat ataatagttt ttgtaaagat caaagaaata
    23341 agtgatctta cctttaatta ggagggtata cctgtatgaa tattgagaaa atgactacga
    23401 cgcttcaaga agcgattgct gaagctcaac agattgcggt cactcgaaaa catcaagata
    23461 tcgacattgc ccatgtatgg aaaatctttt tacaatctaa tcattttggt cgaaatttct
    23521 atacggatgc cggattggat gtcgaatctt ttgaacatga aattgatcgt ctactggatg
    23581 agtatccagt tgtttctggt ggaaacgtcc aatatggaca aaacctcagc cagaatttct
    23641 ttcgattatt gaatgaagca gaccaaatac gtgaaagctt cggcgacgag tttctttcaa
    23701 cggaagtcgt tattttagcg ttgatgaaat taaaaaatta tccgttaact gtttatttga
    23761 ataaaaacgg attatctgaa aaagaattgc gtaaaaacat cgaagagatg agaggaggag
    23821 aaagagtgac ctcacaaaac caagaagaac aatacaaagc attagaaaaa tacggcgttg
    23881 atttagtaca gcaagtcaaa agcggaaaaa tggatccaat catcggtcgt gatgaagaaa
    23941 tccgtgatgt catccgtatt ctttcacgaa aaacaaaaaa taatcctgtt ctgataggag
    24001 aacccggtgt agggaaaacg gcaatcgttg aagggcttgc tcaacgtatc gtacgcaaag
    24061 atgtgcctga aaatttaaaa gataaaacga ttttttcatt agatatgggt gcattgatcg
    24121 ctggagcaaa attccgtggt gaatttgaag aaagactaaa agcagtcttg aaagaagtca
    24181 aaaaaagtga tggacgtatc ctcttgttca tcgatgaaat ccacaatatc gtaggggcag
    24241 gaaaaacaga aggaagtatg gatgccggaa atctgttgaa accaatgctt gctcgcggtg
    24301 aattacattt gatcggtgcc acaactttag atgagtaccg tcaatatatg gaaaaagaca
    24361 aagcgttgga acgtcgcttt caaaaggtat tagtcaaaga accaacagtg gaagatacga
    24421 tcagtattct gcgtggatta aaagaacgtt ttgagatcca ccatggtgtt aacatccatg
    24481 acaacgcatt agtagcagca gctactttat ctgaccgtta tattactgat cggttcttac
    24541 cggacaaagc aatcgatttg atcgatgaag ccagtgcaac gattcgggta gaaatgaact
    24601 ctatgccaac ggaattagat caagttacta gacgtttgat gcagttggaa atcgaagaag
    24661 ctgcactgaa aaaagaatca gatgatgcaa gtaaaaaacg cttgaaaaat ttgcaagaag
    24721 aattagctga acttcgtgaa gaagcaaatg cgatgaagat gcagtgggaa acagaaaaag
    24781 aagaagtcaa ttctgtttca gcaaaacgtg ctgaaatcga taaagcaaaa cacgaattag
    24841 aagatgcaga aaataactat gatttagaac gcgctgctgt attgcgtcat ggtacgatac
    24901 ctcaattaga aaaagaattg aaggaattag aagctaaagc aaaagacagc gagattaaga
    24961 tggttcaaga gtccgttacc gaaaatgaga ttgctcaagt cgttggcaga ttaacgggta
    25021 tccccgtaac gaaacttgta gaaggtgaac gagaaaaact aattaaattg aatgaaacac
    25081 ttcataaacg agtgattggt caagatgaag cagttgatgc ggtcagtgac gcggtaattc
    25141 gttcacgggc tggattgcaa gacccaaatc gtcctctagg ttctttcctt ttcctaggac
    25201 caactggtgt cggaaaaacc gaattagcga aagcgttagc tgagaacttg tttgactcag
    25261 aagatcatat ggtacggatc gatatgagtg aatatatgga aaaacatgct gtgtctcgtc
    25321 tagtcggagc tcctccaggc tatgtaggtt acgaagaagg tggtcaatta acggaagctg
    25381 tcagacgaaa tccttataca atcgtcttgt tggatgaaat cgaaaaagcg catcccgatg
    25441 tcttcaatat cttgttacaa gtcctagatg acggacgctt gactgattca aaagggcgag
    25501 tagtagattt caaaaatacg gttctgatca tgaccagcaa tatcggttca cagttactgc
    25561 tggaaggcgt gactgctgat ggaacgattc cagaagcagt ggctgaacaa gtcaacacgc
    25621 tattacgtgg aaacttcaaa ccagaattct tgaaccgaat cgacgacacg attttattta
    25681 caccattgag cctagacaac gtgaaaggaa tcgttgacaa aatggtggcg caattggcac
    25741 aacgtctgga acatcaagaa atcctgctga caatcagtga tgaagccaaa acgtggattg
    25801 ctgaaaatgc ttatgaacca gcatatggtg caagaccatt gaaacgattt atcactaagg
    25861 aagtagaaac accactagct aaagaaatcg ttgcaggaca tgttatgcct aaatcaaaag
    25921 taacgattac tttacttgat ggacaacttc atttcaaaac agaagagcta gaagaaatcg
    25981 tctaatcttc cattgagact ataaaagaaa aaaggggtct gacacaacta gtgtcagacc
    26041 tccttttttc aaataaacag tgttccagaa gtagtttctt cgaaaaataa gccgaaattt
    26101 cttgaagctg cccgcttctg tcacaacctc ttttattagg tatttttcac tttttctaat
    26161 ttataacttt caaagtaacg ctcatctttt ttactttgag accatgcaaa caatcccatt
    26221 aaggcagcac ctatcgtatt tgtcagcaag tcgcccatcg tatccatcaa tgctgctcgt
    26281 ccgacaaaca gtgtgccatc agaagcagca aaacgttgaa gattcatgcc taagaactgg
    26341 tcgcataaga attcccagaa ctcccaaaac acgccgcaaa gtccagcaaa cgcaaagccg
    26401 aataagagga acaaccaagg actggttttt gatatctcag catctttcat caagtaacca
    26461 atcaatccat agccaagagc tgtcaggacc attggactca ccgcatgtaa gattttgtcc
    26521 caaaaagaga tgatactgat caaatgcatc cctgtgccta aaaagacaga gatgaacaag
    26581 aaaaaccagt aaaacaaaac gattgctgct ggtattttaa gtttgaaaac tttcaaaatg
    26641 acttgtggca tgaaaatcaa tgcaatccct aataaagatt ccacgataaa tgtgattcct
    26701 tgagaagtcg aatatttttg tgtgataaat tcataaaaat tatagcagac aacgaataca
    26761 ccaaaagcaa gtaaagctat ttgcaccttt ttgatttctt taatcactga aagtccctcc
    26821 atctaaaaat ctttttactt ctgaaagcaa ctcaatttct gaagaaacca cttttccgtt
    26881 caatttgatc aaacctattg tatataagtt caggtagtga aattgatttt cagctgtttc
    26941 ttgtagtgca gcgatttttt tcgggtgggt tccgccttgc tgtcgagtat cagtatataa
    27001 gccgatcact gggatgcctt tcgcataagc cacaccgatt tccgatgcta ccccggcatc
    27061 gatcgtcagc ccatctagta aagcaatcat taaatcacta gccaacactt tttctgtgtc
    27121 agcaagagca atcattcgac tgtctgcata agcagttttg tcattgattg cttcattttc
    27181 ttgaggaaga tagatcgaaa gctcagaaga gagctctctg atttctttaa ctaactgttg
    27241 gttatataac aaatcacttt tagcaaacat tggtgcggca aaataaattt tcatctaaac
    27301 atcatccttt ttatcaaaaa taatcgctaa agtaagcttc catgtttgga atgatacgct
    27361 ctagtgactt cagtgtttct tcatctgttt ctaaccgttc gattcttgcc aaataagaag
    27421 cacggcgata attcatcatc aagcaagtca atgtttggat atccagtcga acggattttc
    27481 ctataggttc atttaagaca cggacttgtc cctgttcatc ccatgttaaa gcgaagacac
    27541 cattattcca aggagcgaca ggatcttcaa tgatgaaatg aaaagcatca gctgttccaa
    27601 caaacggaaa ccgttgaagg aattctttta catcaacgat ccgagccata aaatatggtt
    27661 cgatctgctc tttgatctga ctatcttcaa tcaaaaatgc taaaggctca tttttataaa
    27721 tatctccatg tacccagtag atcatggaaa aatgtgcgga aataaagttc cataagccat
    27781 ttcgagcttc ttgatcaaga tagaacattt cttttacgtg aaatatttct tcagctaccc
    27841 agtagaacag aacacctctt ggttcatggt tgctatcgta gtagacagcg gctgtgcgct
    27901 catcttcatt ttcgaaacgc caatactctt cccaatgaaa atcactgcgg aataaagcac
    27961 catggttttg ttgggcaaat ttgtcataaa cggaaaatac gtctggatga tcaactggta
    28021 atcgctcaac cataccactt actgggattt gtttaggtag ctgtgtatct ctgattttaa
    28081 aggaaagttt atcagacatg atttcccatc ctttacgccg atagtagggg atactgtaag
    28141 gatacaaata agagatccat tgcttattct tgcgcatatt atccaatgca acgataatta
    28201 gatcttgcat caatccatgg ttagcatatt ctggataagt tccaactcca gtcacaccac
    28261 ccattttata acgtgcaccg tgaatattga cttcacaagg atagatagcg atttgagaga
    28321 tcagtttatt ttcgtggaac catccgaaca ctttcgatac ttccaaaatc ggttttttgg
    28381 aacggataaa agctcgttta ttctcaaacc cgctttcctc gatgtctgct tcagtcactt
    28441 ggaacacata ggaaagcaat tcattgaatt gatcgatatg ttcttgagtg accggtttta
    28501 attcaagatt ttctctaaaa tctttttgat ccattttttc atctccattt attagcttga
    28561 taacagtata gcaaaattct acaaaaaaaa cttctatagc tgactaatta aaaactcttt
    28621 aaattactgc ttttcgttgg tataatggaa agtgctgatt atatgaaaag aggagacgct
    28681 atggatataa agaaaatgaa agaacgccaa gagcagattc gtaatttttc gatcatcgct
    28741 catatcgacc atgggaaatc tacattggcc gatcgtattt tagaaatgac gcacactgtg
    28801 acgtctcgcg aaatgcaaga tcagctgtta gactcgatgg atttggaacg tgaacgtgga
    28861 atcacgatta aattaaatgc tgtagaactc aattacacag cgaaaaatgg agaaacatat
    28921 atctttcact tgattgacac cccagggcac gtcgacttca cctatgaagt ctctcgaagc
    28981 cttgctgcct gtgagggtgc cgttttagtg gtcgatgcag cacaaggaat cgaagcacaa
    29041 acattggcca atgtttattt agcgttagac aatgatttgg agatcctgcc agtcatcaat
    29101 aaaatcgacc tacccgcagc agatcccgaa cgtgtccgtc aagaaatcga agacgtaatc
    29161 ggaatcgatg ctagtgaagc tgtattagcc agtgccaaat cagggattgg gattgaagat
    29221 attctcgagc agatcgtgga atatgttcct gcaccaagtg gagacttaga tgcaccgcta
    29281 aaagctttga tctttgactc tatttatgat agttaccgcg gtgttgttct aaatgtccgg
    29341 atcacggacg gtatggtcaa acccggagac aaaatcaaac tgatgagtaa tggcaaaaca
    29401 tttgatgtta cagaggtcgg ggtcttctcg ccaaaagcag ttgctagaga ctttttgatg
    29461 gtcggtgatg tcggttatat cacagcaagt atcaaaactg tccaagatac acgagtaggg
    29521 gatacagtaa cgttagcaga caatcctgcc gctgaagctt taccaggtta ccgaaaaatg
    29581 aatccgatgg tttattgtgg tctttatcca attgatactt ctcgttacaa cgatttgcgg
    29641 gaagctttag aaaaactgca attgaatgat gctgctttac aattcgaacc agaaacctct
    29701 caagcattag gttttgggtt ccgctgtgga ttcctcggac ttcttcatat ggatgtcgtc
    29761 caagaacgct tggaacggga attcaatcta gaattgatca cgactgcacc atccgttatt
    29821 taccatgtta ataaaacgga tggtacgact gctacagtag ataacccggc agattttcct
    29881 gaacctgtaa cgattcagga tgtagaagaa ccattcgtca aagcacagat catggtccca
    29941 aatgattttg tcggtgcagt aatggaactt tctcaacgaa aacggggaga attcattacg
    30001 atggattatt tagatgatta ccgagtaaat gtcgtctata atattccgct ttctgaaatt
    30061 gtctttgact ttttcgacaa attgaaatca agcacgaaag gctatgcctc attggattat
    30121 gaaatgtctg gttatcaaaa aagcaagtta gtgaagatgg acatcttgct gaatggagaa
    30181 aaagtcgatg cattaagctt tatcgttcac cgagactttg cctatgaacg tggaaaagca
    30241 atcgttgaaa aactgaaaaa actaatccca cgccaacaat ttgaggtgcc aatccaagca
    30301 gctattggac aaaaaatcgt tgcccgttca gacatcaaag ccttgcgtaa aaacgtcttg
    30361 gctaaatgtt atggtggaga tgtttctcgt aaacgtaaac tcttagagaa acaaaaagaa
    30421 gggaagaagc ggatgaaaca aatcggctcc gtcgaagttc cgcaagaagc cttcatggcc
    30481 gttctgaaaa tggacgagga cgaaccgaag aaatagcaag ggtttgtttg aaaacagtgt
    30541 aaaaaataaa ccatgtttac atggatttgc caccggtttg ccaccggtgg t
//
LOCUS       DARBDN010000020        30410 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000020 DARBDN010000000
VERSION     DARBDN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.020"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(50..247)
                     /locus_tag="SCH06_000992"
     CDS             complement(50..247)
                     /locus_tag="SCH06_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HEG1077589.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(641..2368)
                     /locus_tag="SCH06_000993"
     CDS             complement(641..2368)
                     /locus_tag="SCH06_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEG1077590.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2361..3554)
                     /locus_tag="SCH06_000994"
     CDS             complement(2361..3554)
                     /locus_tag="SCH06_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEG1077591.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3741..4385)
                     /locus_tag="SCH06_000995"
     CDS             complement(3741..4385)
                     /locus_tag="SCH06_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1077592.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4479..4613)
                     /locus_tag="SCH06_000996"
     CDS             complement(4479..4613)
                     /locus_tag="SCH06_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HEG1077593.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4615..6747)
                     /gene="feoB"
                     /locus_tag="SCH06_000997"
     CDS             complement(4615..6747)
                     /gene="feoB"
                     /locus_tag="SCH06_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HEG1077594.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6744..7217)
                     /locus_tag="SCH06_000998"
     CDS             complement(6744..7217)
                     /locus_tag="SCH06_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HEG1077595.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7618..7842
                     /gene="nrdH"
                     /locus_tag="SCH06_000999"
     CDS             7618..7842
                     /gene="nrdH"
                     /locus_tag="SCH06_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEG1077596.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8001..10160
                     /gene="nrdE"
                     /locus_tag="SCH06_001000"
     CDS             8001..10160
                     /gene="nrdE"
                     /locus_tag="SCH06_001000"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEG1077597.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10210..11175
                     /gene="nrdF"
                     /locus_tag="SCH06_001001"
     CDS             10210..11175
                     /gene="nrdF"
                     /locus_tag="SCH06_001001"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEG1077598.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11264..12403)
                     /locus_tag="SCH06_001002"
     CDS             complement(11264..12403)
                     /locus_tag="SCH06_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEG1077599.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12712..13425)
                     /locus_tag="SCH06_001003"
     CDS             complement(12712..13425)
                     /locus_tag="SCH06_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEG1077600.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13679..14380)
                     /gene="nagB"
                     /locus_tag="SCH06_001004"
     CDS             complement(13679..14380)
                     /gene="nagB"
                     /locus_tag="SCH06_001004"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEG1077601.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14614..16146
                     /locus_tag="SCH06_001005"
     CDS             14614..16146
                     /locus_tag="SCH06_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEG1077602.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16337..17539)
                     /locus_tag="SCH06_001006"
     CDS             complement(16337..17539)
                     /locus_tag="SCH06_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077603.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17621..18310)
                     /locus_tag="SCH06_001007"
     CDS             complement(17621..18310)
                     /locus_tag="SCH06_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEG1077604.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18416..18784)
                     /gene="rplL"
                     /locus_tag="SCH06_001008"
     CDS             complement(18416..18784)
                     /gene="rplL"
                     /locus_tag="SCH06_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEG1077605.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18837..19340)
                     /locus_tag="SCH06_001009"
     CDS             complement(18837..19340)
                     /locus_tag="SCH06_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEG1077606.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19544..19671)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19750..20439)
                     /gene="rplA"
                     /locus_tag="SCH06_001010"
     CDS             complement(19750..20439)
                     /gene="rplA"
                     /locus_tag="SCH06_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEG1077607.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20543..20965)
                     /gene="rplK"
                     /locus_tag="SCH06_001011"
     CDS             complement(20543..20965)
                     /gene="rplK"
                     /locus_tag="SCH06_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEG1077608.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21308..21976
                     /gene="sdaAB"
                     /locus_tag="SCH06_001012"
     CDS             21308..21976
                     /gene="sdaAB"
                     /locus_tag="SCH06_001012"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEG1077609.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21989..22861
                     /gene="sdaAA"
                     /locus_tag="SCH06_001013"
     CDS             21989..22861
                     /gene="sdaAA"
                     /locus_tag="SCH06_001013"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEG1077610.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22952..23971)
                     /locus_tag="SCH06_001014"
     CDS             complement(22952..23971)
                     /locus_tag="SCH06_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEG1077611.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(24144..25049)
                     /locus_tag="SCH06_001015"
     CDS             complement(24144..25049)
                     /locus_tag="SCH06_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEG1077612.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(25108..25653)
                     /gene="nusG"
                     /locus_tag="SCH06_001016"
     CDS             complement(25108..25653)
                     /gene="nusG"
                     /locus_tag="SCH06_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEG1077613.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25754..25924)
                     /gene="secE"
                     /locus_tag="SCH06_001017"
     CDS             complement(25754..25924)
                     /gene="secE"
                     /locus_tag="SCH06_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEG1077614.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25948..26100)
                     /gene="rpmG"
                     /locus_tag="SCH06_001018"
     CDS             complement(25948..26100)
                     /gene="rpmG"
                     /locus_tag="SCH06_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEG1077615.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26262..26906
                     /locus_tag="SCH06_001019"
     CDS             26262..26906
                     /locus_tag="SCH06_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEG1077616.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26962..27465)
                     /locus_tag="SCH06_001020"
     CDS             complement(26962..27465)
                     /locus_tag="SCH06_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEG1077617.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27478..27524)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28062..29027
                     /locus_tag="SCH06_001021"
     CDS             28062..29027
                     /locus_tag="SCH06_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEG1077618.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29126..30298)
                     /locus_tag="SCH06_001022"
     CDS             complement(29126..30298)
                     /locus_tag="SCH06_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077619.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30285..>30410)
                     /locus_tag="SCH06_001023"
     CDS             complement(30285..>30410)
                     /locus_tag="SCH06_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077620.1"
                     /translation="KLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
BASE COUNT         9273 a         6254 c         5394 g         9489 t
ORIGIN      
        1 tatatcatta tataattcat gaacaatttg cttagcattt tttttcattt tagcacttcc
       61 ctggaattgc tccacctaaa aaaccaccta tagacattcc tgcaatacaa gtagttgcct
      121 tggcccaatc gaccgtacat ttatttttag tgcaatacac tccatttcca taatattttc
      181 cactatgagt ggtaccccca tagataagtt gtgtctcttt aatagacaaa atttttaaat
      241 gtttcataat ctaatcaccc ctaaattaat gtttttagac tattattcta acattcatta
      301 aatttcaaaa aacaattcct tcttgaaacg tagcaaaata attcctgaat aagaatttaa
      361 tcacttttaa gtatataaac tatgtatatt ctttaatatt ttttgagaat gcacttcgta
      421 cataataaac tttaatcaca ttagtctttc atacctacga tcgatctctt tgactcgcac
      481 ccataaattc ataatagttt gtcggcgtct ttggacgttt cgaagatgag ctacgcattc
      541 tcttttttta tagacaaaaa agatagagac gaacatggag cttccaaatt tggatatttg
      601 atccaatttt ggaagctcca tttatttcgt gtctgtcttt ttattttttc cagctttcga
      661 ctaattcttg gttctctttg atccagtctt ttgctgcttg ctgtggatct tttccattgt
      721 tgatttccaa cataactttt tccatatctt tttctgacca atggaaattg tctaatactt
      781 tgtaagcttc tggctggtct tctttcaatc cttttcgaac catcgtatgg atctgctctt
      841 cgcttcccat tccgttttca ggatcttcta agtatttcag atcatatttg gcaaacatcc
      901 aatgaggtgt ccatcctgta actacaattg gttcgtgttt tttgatcgct tgacctagtg
      961 caacggtcat tgctcctgaa gaagatgtct ctactttcca gtctttcaag ttgtcatatt
     1021 tttggatcgt gttttcagca gccgtaacta caccagctcc tggctcgatt cctatgattt
     1081 tcttacctgc ctgatcggtt aactcatcga tcgaatttac atccatgtag gctggcactg
     1141 ctaaaccaac ttttgctcct gtcaaattgg cacctaggtc ttcgacttga tctttatatt
     1201 gtgcatattg tgaaccatga gttttaggta gccaagctga aaccatggca tctgactcgc
     1261 catttgaaac agatttccac atgattgaat tatctaatgg cgtcatcgtt acatcatagc
     1321 ccatttgttt caatacttca ccgactacat ttgttgaagc aacttctgta tcccattcaa
     1381 cataagataa gttgatacgt tttgtttctt tggcagatga aaaactccct ataccaatcg
     1441 cacctaagat cactactact acagcaccaa tgatcagtcc ttgacgtttt ttacttttct
     1501 gtgttgttgc tcctgcagct tttttattgt ttggctggtt caaatgctgt gtaaaacggt
     1561 caatgatgat tgctaagata actaatgcaa ccccgttgac aaatccattc ccgacttgtg
     1621 ctctttgcaa tgctgataat acgccgcgtc ctaagccggg tgcaccgatc atagaggcaa
     1681 taacgaccat tgaaagtgac agcattgttg tttgattgat ccctgccatg atcgtacttt
     1741 tagctaaagg caattctagt ttgaatagtt tttgacgact tgtgctcccg aatgaatcag
     1801 aagcttctac taattcttta ggaacttgtc gaatccctaa attcgtaaaa cgaacggttg
     1861 gtggcagagc aaagatgact gaggcaaata cccctggaac catcccgata ccgaaaaatg
     1921 caactgctgg aatcaaataa acgaatcctg gcattgtctg cataaagtca aggatcggtt
     1981 tgataatact ttgggcttta ctgctttttg ccatcaagat ccctaatggt accccaatga
     2041 tgatcgagat cacactagat aaaagaacaa gtgtgacagt attcatcaaa tcattccata
     2101 gaccttggtt ataaataaac catagaccga ttaatgtgaa caacgtaagt cctggacgtt
     2161 tcttagaaat aaagaaagct gctaccgtca ataacaagat aaacaaagga gctggaatca
     2221 ctaacagtaa atttgtaatc cccgacatca ctgcctgtcc aatcgtttgt aaaaatgaaa
     2281 ataggccaga aaaagttgtc gtaaaccatt ctgtgatatt ttctacccag tttgccactg
     2341 gtaattgata gttcaataga ttattcatgt tcactcacct cgcttgtttc tgctaatgct
     2401 tcaatcacac tacctcggat gacgacacct tttaattttc catcctctac aactgcaagt
     2461 ggagtcggtg agtcataaat aatattgaaa atatcactta ccaccatgtc tttcccaatc
     2521 accgtcacat tttcatctag gaagtcgatc aatggacgtt tttgcttcct agcttctaac
     2581 gcttgatctg cagtgatgat ccctttcagg tgtctctttc tgtcaacagc catcagcatg
     2641 ctgacttctt cattacgcat ccttgtcaat gcaacgtttg gtccatcaga ttcgatattc
     2701 gtcgtcaatg caggtaccat gatgttttga gccgtaagca ctttggaacg atcgacttct
     2761 tccacaaatt cacgtacata atcatttgct ggattggtca atatttcttc acctgttccg
     2821 atctgcatga tttcgccgtc tttcatcaag gcgattctgt ccccaatccg taaagcttca
     2881 ttcaaatcat gggtaatgaa aataatcgtt ttttgaacat tggcttgcag gtccagtaat
     2941 tcgtcttgca tttctcgccg gatcagcgga tcaagagccg agaacgcttc gtccatcagc
     3001 aagatctcag gatcatttgc taaagctctg gctaggccaa cccgttgttg catcccacca
     3061 gataactgac taggatattg gtctttaaat gaaagcaaac tagaattttc taatgctttt
     3121 tctgcttttt cttgtcgttc ttctttaggt acaccacgga cttctaaccc gtattctgta
     3181 ttttccaaga tcgttcgatg tggaaacaga ccgaagtttt ggaaaaccat attgatttta
     3241 tgacgacgga cttctcgcaa ttcttctttg cttaacttcg atacatcttc tccatcaata
     3301 tagatactgc ccgaagttgg ctcaatcaga cgattcaata gacggatcaa tgtggatttc
     3361 ccactcccgg aaagccccat gatcacgaag atttctcctt cttttacgtc aaaattcacg
     3421 tcatacacac caaccgttgc accggttttc tttaaaatct ccgttttcgg ctggtgatca
     3481 ttcatcatat ctaaagcggc ttgtgtcttt ttaccaaata tctttgttaa atgttttact
     3541 tctactttta ccaaacaaat tctccttttt tatgtaaatt catttttctt tctgaaaaaa
     3601 gtgaccacac tatgttaaca tcatgtagtc actttgtcaa aaatgaaaga aatttgcttg
     3661 tccaaactga aaaaaacttg gctaaatctt tgtaaataaa aggtttagcc aagttaatat
     3721 ttttttaata tttcacacaa tcattctgca agctgatgct ccgggtaaaa aaagtttgtc
     3781 atacgctgta gtgtatattc atttccaata aaatgaacga tgtcccctgc cgtaaattta
     3841 gcataggggc caggtgaaac aagcagttct tcattatgag aaattgcgat aactgtggcg
     3901 ccagtcgcct gccagatatt caactcgcta attgaacggt ccagatgcat tgctttttct
     3961 gataaagata attcaaacgg aagtaaagga ttcatcttat gtattcgctt cgtttgattg
     4021 accagctgat ccaataattg agaaaaatga ttcagctcat cttgttgctt ctccacactt
     4081 gccatgattt ctgcttttgt atcttggatg gattgtacat cttgatattg caataggaaa
     4141 tcttttgctt tttccttcga agcaacaaat gccccacttc catgccgtac ttccatgatt
     4201 ccaagatcta ccagcacatt gatagccttg cgggtagtct caggagaagc attgtacgta
     4261 ctggcaagtg ttgagcgggc atggatcttc tcacccactt tatatcggtt ttcaacgata
     4321 cgttcggcta aatcaacagc aatctgctgg tagcgcgggc ggacgatttt tttctttcca
     4381 gacattttct ttcctctttc tttttttact ttccctcatc ttactatgct ctagcaaaat
     4441 aagcaaaaaa ggggagaata gcctcttgca acgactgatc atcgcttgat ctgttccttt
     4501 tttactgggc aagctgtttg acagtcatca caattcttac cggattttaa acgagtatag
     4561 acaattgcgc ctgcacttcc aaagattaac acacttaata agaatgtcgc catcctattc
     4621 ctctccttct aatgacaata tagtataaaa ctggttcttg gattttggct gacggaacaa
     4681 aacataaacg agtcctatca tcagtaaaat agcaagatac gtccctaacg ctacctgtcc
     4741 accctccaat aagtgtccca actgataaat cacaaaacta actaaataag ctaaaccgca
     4801 ttgatagcct atggcgatcc aagtccattt cttggcattc atttcccgat ggatagcccc
     4861 aattgccgca aaacaaggcg cacaaagtaa attgaaggct aacaatgaat aagctgctgc
     4921 gggagtatat gtgtgttgta gcacttgcca gatttctctg ccattttcgg atacttccgc
     4981 atgaccaaac aaaataccaa atgtgccaat aatattttct ttagcgacca atcctgtaat
     5041 cgctgcgact gttccttgcc agtttcccca accaagcggc tgaaaaacaa ctgccaggat
     5101 tcgcccgaaa aaggctaaga tactttggtc ttcagaaaca ggttgagcat aaaaattata
     5161 agaagagctg aaccagatca cgatactaga aacaaagata atcgttcctg cttttttaac
     5221 aaaagacttg ctgcggtcat aggtttgtct taggaccgct gaccattgag gaaaatgata
     5281 tgcgggcaat tccatgataa aaggagctgt atctccagca aacaaacgtg tttttttcaa
     5341 gctgattcca gagaaaataa ttgcagtcat accaagaaaa taggcagaag gagctaccca
     5401 agattgatga ggaaaaaagg cccctgctac taaggcaata atcggcaact ttgcagaaca
     5461 aggcatgaag gttgtgacca tgatcgtcaa acgacgatct tgctcgtttt caatcgtgcg
     5521 actggccatg acgcctggca ctccacatcc tgtagcaatc agcataggaa tgaaggattt
     5581 tcctgaaaga ccgaatttcc tgaaaagtcg atccatgaca aaagcgatcc tcgccatata
     5641 tccgcagtct tccagaaagc tcaagcataa aaacaatata atcaattgcg gtagaaatcc
     5701 taacactgct cccacgcctg cgatgatgcc gttcaagatc agctcctgca tccatcccgc
     5761 tacttgccat tcagctaaca atctgccaac atgttctggt aaccatgtac caaacaatgt
     5821 gtcattgatc caatctgtcc ccattgttcc tactgtttga atagccagat aatagatcag
     5881 ccacatcaca aatgcgaaga tcggcaaggc taaccaacga ttcgttgcaa tctgatcgat
     5941 tttgtcactc atcgataatt ggaaagaatc atttgacaca acacagagtg tacatagttg
     6001 ggtaataaat tcataacgtt cattgaccag aatcgtctca ctatcgtcgt ccaatagttt
     6061 ctctgttaac tggatcagtt gctcgatctc tttttgctga gaaactgcta tctcgtaatc
     6121 ctctcttacc ttctgatctc gttcaaaata tttcattgca taccagcgtt tcttgccgct
     6181 ttgttctcct agtacatctt caatttcatg taaagctgct tctaaacgtg gatcatatgt
     6241 acagggaaca ggaatagaag gccgcttttt tgcagactcc tgaatctttt cgattagttt
     6301 ttcgattcct tgctttttca atacgctgat tggtaaaact ggtacaccaa gaccatagga
     6361 aagcttttct agattgattt tttttccttc ttttttgatg acatccatca tattcagacc
     6421 aatgatcata ggaatgtcta aatccaataa ctgcgtagtt aaataaagat ttcgttctaa
     6481 attggtagca tcaataatgt tgatgatcag ttcaggctgt tcctgaacca aataatctct
     6541 tgcaatcact tcttctggtg tataaggaga caaagaatag atgccgggta ggtcctgaat
     6601 atgaatgttc ggattttttt tcaacgatcc ttcttttttt tctactgtta cgcccggcca
     6661 attccctaca tattgattcg aaccagtcaa gagattgaac aagctagttt tcccgctgtt
     6721 tggatttccg actaacgcga tattcattct ttttcctccc tttgtatcaa gattagttcg
     6781 gcctctgact ttcgtaacgt cagttcatac cctcgcactg tcagttcgat tggatctccc
     6841 agaggggcta gttttcggat aactattttt acatttcgcg tcaatcccat atccattaac
     6901 cgtcgcttca ctgcgccttg tccgtggatt gctacgacga tcccagtctc tcctgctttt
     6961 aattgatcaa gagaagtcca gctttcagag gaagcagtct ttttattgac aaagatttga
     7021 cctagtattt cccgacttac tgccactcga tgacttttta ccagtaaaat ggcattgttg
     7081 cctgataaat tgacgacgac gattttactt ccggcaacga tcccgatatt ttgcaaatgg
     7141 cgttttgttt tttcttctgt ttcgattcgt tcgacttgat aaacgaaatt ctgctttgcc
     7201 tgcgctaagg tctgcatatt gattcctctc ttgtgaaata aatcatgtat taaaatcatt
     7261 cattatatgt tctaattttc ttacgtgtta cgcaaataaa tgagaatcat tctcacatag
     7321 aatactctcg gtaattgaga atgtcaatta tacttgtgat attatgagcg aatctttagt
     7381 attgatagat aaaaatgaga aaaaaatatt tcttcatagt tttccacaat tttttctcta
     7441 ttaaatttgc tattttccca cacgatactt gttttcagct cttttttcaa aaacacaaaa
     7501 cttagtattc cacagtttcc acaacacaat atgtagtgtt tgttgtttga cttttttact
     7561 aagagtttta tactatctat tatagataat aagaatgtgt tagaggaggc actcaccatg
     7621 aacgtaaaaa tcttttctaa aaataattgt atgcaatgta agatggtcaa acggttttta
     7681 acagaaaatc aaattgcttt tgaagaagtc aatatcgatg aacagcctga agcagtagac
     7741 tggttgaaag cacaaggatt ccaaagtgtt cctgtcatta cttctgatgc agaaacagtt
     7801 atcggattcc gtcctgatca gttgcgtaaa cttgccagct aacatgacta aaagaatcaa
     7861 aacgtgatac atggatttga agggcttgag acagcaccag tttttgtcgc aaacttccaa
     7921 atcctttttt aaagcttaaa aacaatgcaa tgatttgcaa tcaagcatca tcaaatacga
     7981 aatgaaggtt gggcgtacgt atgagtctta aaaatttaca agatgtcagt tatttcaagc
     8041 tgaataatga aatcaatcgg ccagtcaatg gtcaaatccc tttgaataag gataaagaag
     8101 ctttagttgc cttttttgag gaaaatgtca aaccaaatac gatgactttt ctatctatta
     8161 tggaaaaaat caattacttg atcgatcaag aatatataga agcagaattc attcaattgt
     8221 attcaccatc atttattgaa aagctatatc aatttttgga cgagcaacat ttttctttca
     8281 aatcttttat ggctgcttac aaattttatt ctcaatatgc gttgaaaacc aacgacggtt
     8341 ccgcttatct ggaaacttat gaagatcgag tagccttcaa tgcgctttac tttgcgaacg
     8401 gggatgaaga attagcactt gctcttgcag acgaaatgat ccatcaacga tatcagccag
     8461 ctacaccttc tttcttgaat gctggacgta aacgtcgggg cgaattggtg tcttgtttct
     8521 tgactcaagt cactgacgat atgaactcta tcgggcgctc aatcaactct gctttgcaat
     8581 tgtcccgtat tggtggcggc gtagggatta ctttatcaaa tcttcgtgaa gccggcgctc
     8641 ctatcaaagg atatgagggt gctgcaagtg gtgtcgttcc agtcatgaaa ttattcgaag
     8701 atagtttcag ctattctaat caattaggtc agcgtcaagg agctggcgtg gtttatttga
     8761 acgttttcca tccagacatt attgctttcc tttcagcaaa aaaagaaaat gcagatgaaa
     8821 agattcgcgt aaaaactctt tctcttggcg tgatcgtacc tgataaattt tatgaattga
     8881 cacgtaaaaa cgaagatatg tatttattta gtccatatag tgtcgaaaaa gaatatggtg
     8941 tcccattctc ttatgtaaat attacagctg agtatgatca tctagttgca aatccaaaca
     9001 ttcgcaaaca aaaaatcaaa gcgcgtgatc ttgaaaatga aatctcaaaa ttacaacaag
     9061 aatctggcta tccttacgta atcaatattg atacagcgaa ccgcgagaat ccaatcgatg
     9121 gcaagatcat catgagtaat ttatgttcag agattttaca agttcaaacg ccttctgtga
     9181 ttaacggcaa acaggaatat gaagtattag gaacggatat ctcatgtaac ttaggctcga
     9241 caaatatcgt gaatttgatg caaagcccta actttggtca atctgtgcgt acgatgactc
     9301 gtgcattgac atttattaca gatgcatctg atatcgatgt cgtaccaccg atccaaaacg
     9361 gaaataagct gaatcatacg attggattag gtgccatggg cttacacact tatcttgcaa
     9421 aagaacaaat ggaatatggc tcagaggatt cattagactt tacaaatatt tacttcatgc
     9481 tgttgaatta ttggacactt gttgaaagca acaatatcgc tcgtgaaaga aaacaagttt
     9541 tccataattt tgaaaaatca gcttatgctg acggcactta tttcgaaaaa tacgtaactg
     9601 gagaattcca gccaaaatca gaaaaagtca aagcattgtt tgaaggcatt tttatcccaa
     9661 ctgctgaaga ttggaatgct ttgaaacaag cagtaatgaa agatggactg tatcatcaaa
     9721 atcgcttggc agtagcacca aatggctcaa tttcatatat caacgatacg agtgcaagta
     9781 ttcatcctat cactcgcatg atcgaagaac gccaagagaa gaaaatcggt aaaatttatt
     9841 acccagcgcc ttatctatcc aatgagacga ttccgtatta cacttctgct tatgatatgg
     9901 acatgcgtaa agtaatcgat gtttatgcaa tggcacaaca acacgtcgat caaggcatga
     9961 gtttgacttt attcatgcgt tctgaaatcc cagaaggcat ttatgaatgg aagacaacaa
    10021 cgaagcaaac gacacgtgat ttgaatattt taagacatta cgctttccac aaaggaatca
    10081 aatccattta ttacgtacgt acctttactg atgatgcaga agaaatcgga agcaatcaat
    10141 gtgaaagctg cgtgatctaa tatcatagat agattcgctt attcatattt taattaaagg
    10201 agcattctca tgtcagaaac atattatgaa gcaataaact ggaatgaaat tgaagatatc
    10261 attgataaat ccacttggga gaagctgaca gagcaatttt ggctagatac acgtatccca
    10321 ctttcaaatg acctagatga ttggcgtaca ttgtctcaat tggaaaaaga tacagtagga
    10381 catgtatttg gcggtttgac actgctagat actgtccaat ctgaaagtgg catggatcag
    10441 ttgcgtaaag atgtccgcac tccccatgaa gaagccgttt tgaacaatat tcaattcatg
    10501 gaatccgttc atgccaaaag ttattcttct atttttagta cactgaatac gaaaaaagaa
    10561 atcgaagaaa tttttgactg gacaaatacg aatccttatc tgcaaaaaaa agctgagcgt
    10621 atcaatgaaa tctacaaaca cggtacaccg ctagaaaaga aaattgccag cgtcttttta
    10681 gaaacattct tgttctattc aggtttttat actcctcttt attatttagg aaacaacaaa
    10741 ttggctaacg tagcagagat catcaaacta atcatccgag atgaatctgt acatggaacc
    10801 tacatcggtt acaaattcca attaggattc aacgagttac ctgaagcaga acaagaaacg
    10861 ttaaaagact ggatgtacaa tcttctttat gagctttacg aaaacgaaga acgttataca
    10921 gaagaattat acgatccaat cggctggaca gaagaagtca agacattcct acgctataat
    10981 gccaacaaag cattgatgaa cctagggatg gatccactct ttccagatac tgccaatgat
    11041 gtcaacccaa tcgtaatgaa cgggatttca acaggcacaa gcaaccatga cttcttctca
    11101 caagtcggaa acggctattt gttaggtcat gtagaagcga tgaaagacga cgattatttg
    11161 attggattgg aataaggatt tattttaatt caaaaatttt tcgaaaaata aaaagagttt
    11221 agcgtacaga tattttaaat gtacactgaa ctctttttta tgcttattca cttgtttctt
    11281 ccagcacttt tggactgtct aacttttccg aaacatgttc cattcttctc aataaataga
    11341 ttttccggat atttaatatt atcgtcttaa tcactgcata gacaggtatg caaatcagca
    11401 tgcctaatat tcctgcgaca cttcctgctc caatcaatac caagatgatc gtcaaaggat
    11461 ggatattcat tgatttccca aataacaacg gcttgatcaa atttccatct aattgttgga
    11521 tcactaaaat cgacaacgcc atatacaaag cttgaaatgg agagataaac aaaccgacaa
    11581 tgattgctgg taccgctcca ataaaagggc cgacatacgg gataatattc gtgattccgc
    11641 aaatgaccgc aagcaacaag ctataaggct gatcgaatat tctcattgcc aaaaagctca
    11701 ttacaccaat aatcaaagca tctaagatcg tactgctgat ataggcagat aatgtttcgt
    11761 ttaattcttt taccgtttgg cgtaactctt tacgaatcgc tttcggaaag aagtgagaca
    11821 acgcatcaat aaatttgtgc ccatccttga acataaatag caaaataaat ggaacggtaa
    11881 ataacaaaat aaaaaattgc atcataaatg aaatgatttt tgagacactt gcagataaac
    11941 tgactaatat gatattgaac aaattactaa gagataaatt tgctgatgct aattgttctt
    12001 ccaaattgaa atttttaaac tcttcccgct gcgccaattc atttaaccat ttgcttgttt
    12061 catctgcata cattggcaag ctctgggtca attgaattgt ctgttccatt aactgaggca
    12121 ctacattcat gacagttaaa acaactaaaa tgattacgac caaaaacgtc aataaaaaac
    12181 cgaacactct cgggatccga tgcttttcga gaaaaacaac gattggatcg aacatataat
    12241 agataaaacc agcaacaagc aatggtaaaa aaactgccga aagcattttc aatattggac
    12301 taaaaatatt cggcatttgt aaaataaagt acacgccgat gatcgtgagt actagctcca
    12361 ctgtccagaa aaataatttt gattgtttaa aacgtgattg catacatctc ctccaaggtc
    12421 ctttgatact tctattctat catttaacaa agagttacgc gctgagattt tcatttgctt
    12481 aaaaaaaaca aaaaaaataa acatatttta atgagtagac gagtacttaa acaaaaacac
    12541 ggtttggagt agtgacaaaa attatactgc agtccctttt tccaaataaa cggtgttcaa
    12601 aagcttgcat cttcgtaata agcccagcca aacgaaaaat ataaggaact atttttattt
    12661 ggctgggctt attacttgat gtaggacatc tattttacaa cctcagatca tttattgcgc
    12721 aatactgact aaatgcaact ttgtgatatt tttgtgtacg gacaactcct cgatcacatc
    12781 ggcataagtg agcccttttg gaagatcaat cgtatagata tttttgtaca ctcggtagtc
    12841 atcaacgaat tttacgtcaa aattcacatc ttcgattacg atatttttct cttcaaaata
    12901 atcggtaaga aaatctttgg tttcttttct atggataaat tggatttcta actttttagt
    12961 cgtaggtaca tggatcacgc gtttcactac tgtgagtgca atagcaatcc cgataaaact
    13021 gatgatcgca atggaatagt aacccatgcc gatggcgatc cctaatccag caattgccca
    13081 taaagaagcg gcagtcgtaa gtcccgtcac cgattgtttc gtgacgatga tcgttcccgc
    13141 gcctaagaaa ccgacaccac tcaccacttg agcaatcagc cttgcttcat ctgaacgaat
    13201 cgttccagca agctgtggat actctaaagc atctcttaat gcaccactag cgatctcaac
    13261 ttggatcaat gcaatgatac atgctcccat acaaactaaa atatgcgtac gcatacctgc
    13321 tggacgattt ttatattgtc gttcaaaacc gattgctccg ccaaatagca tagcgatccc
    13381 taaacgtaaa ataatctctg gaattgtcaa taccatatca ttcatctaaa caccctccag
    13441 tccaatatat catgtctgaa aggagcagac aaaaaaagtg caatttttac ctcttacgaa
    13501 aaaaggactg tgacaaaatt tttgtcatag tcctttttat gaataaacgg tgttcaatca
    13561 gctgaccctc ggtattactc aacaaacggc aaaatatggg gagctatttt tcctttgtct
    13621 tctctaatac tcaggtcaaa acgctgattt cacaacctct ttagcctact attgaaaatt
    13681 acaacttact tgctgcttct tcatcgatga tcacaacaac attgtcgtga ttttgcaata
    13741 cacttgctgg caaatgattc gttacaggtc cttcaatcat ccctttgatt gcatcagctt
    13801 tgctttcgcc aaatgccatc aagacgattt ctttactttt cataattgaa ccgattccca
    13861 ttgaaacagc ttttgttggt acatcttctg ctttatcgaa gaatcgtttg tttgcattga
    13921 ttgttgattc tgttaagtca actactgaag tcgttccgtc aaatgaagca ccaggttcat
    13981 tgaaaccgat atgtccattt tgcccgattc ctaagatttg gatatcgatt ggatgtgcat
    14041 cgatgatttg atcatacttt ttgcatgctg cttccagatc ttctgctttt ccatctggta
    14101 caaacgtttc tttgaatggt tttttatcaa ataattggac atccatgaaa tgacggtagc
    14161 tttgttcatc tgaaccgcct agtccaacgt actcatctaa gtttacagaa gtcatttcac
    14221 tgaaatccaa atcgcttgaa gtcatttctt tatataaagt aactggtgtg cttcctgttg
    14281 ccaatcctaa tacttttgca cctttgttca taccttcttt gatgatttca aatgcttttt
    14341 ttccgccttc ttcagcgttt tttacacgaa tgatttccat agtgattgct cctttatatt
    14401 ttggtatagc ccaattatag cattcttttt ttctttttac aataattagt atagaccaaa
    14461 ttgcattttt ttcattttct tgacaataaa taggaatccg tgttaggttt cataagatgg
    14521 ttcaatcaaa caatccatgt tgcatgaaaa ccaagcaagt gattcactgt ggacgcttta
    14581 tgtctgcagt ttttttatga aaaaggagtt attatgagta tactgacatt aaacaacatt
    14641 acccagcaat ttggcgacaa aatcctctat gaaggtgtcg atctgcaatt aaatgctggc
    14701 gaacatcttg ggctgattgg acaaaacgga gccggtaaaa gtacattgat taaaatcatc
    14761 actggtgaga tcttaccaga tgacggacag atccattggc aaaaaaatat tcacaaaggt
    14821 tacctcgatc aatatgtgga agtcgatgaa acattaacaa tcgaagaatt tctaaaaact
    14881 gcgtacgcaa aagaatacga aaaggaagaa aaaattgctt ttctttacca aacatatagc
    14941 gagaccttcg atgattcctt gctggaaaaa gctgggaaac tccaaacgga attagaccaa
    15001 ggagtgtttt atcaaatcga caccttagtt gctgagatga gcagcgggtt ggggatcgat
    15061 gtcttaggtt tagattcact gttgaaaaat ctaagtggtg gacaacgttc aaaggtgatt
    15121 ttagcaaaac tacttttaga aaacccagat gttctgatct tagatgaacc aaccaatcac
    15181 ttagatgatc agcatatcca atggctgacg cagtttcttc aggattttga cggtgcgtat
    15241 atcgtgattt cccatgacca agaatttctt gatcagatca ccacccatat cgcagacatc
    15301 gagtttggaa agattactaa gtatactggc catctaaaac aagcattgaa acaaaaggaa
    15361 caaaatcgcg aaagctattt gcgccaatat catgctcaac aaaaacaaat cgaaaagacc
    15421 gaagcttata ttcgaaaata caaagccggt tcccgatcaa cgatggcaaa aagccgacaa
    15481 aaacaattag ataaaatcga acggctgacg cctccagctt cagcaagtaa agctgtcttt
    15541 gattttccat tctcgcctat tgtcacgaca ttagcagtgg aaacaactga tttagtcatc
    15601 ggatatgatc gaccgctact tgcacccatc aatttgacca tccgctttgg tgaaaatatt
    15661 gccattcgag gcttcaacgg gattggaaaa tctactttat taaaaacact gatcggtgag
    15721 attgaaaaaa taagtggcga tttccacttc ccagataaca caaaaatcaa ttacttttca
    15781 caagatctgt actgggaaaa tccattagaa acaccactac aatatttaag cagtcaattt
    15841 ccaaaagcga ctatcaaaga attacgtcgc caactagcta aagcagggtt agttaatcaa
    15901 ttagcaagtg aacctctcac tacattaagt ggtggggaac aaactaaggt gaaacttgca
    15961 cagttgacaa tgaaccaagg taatttactg attctcgatg aaccgacgaa ccatatcgat
    16021 caagaaacga aagaaagctt acaagacggg atacagaaat ttccaggaac agtaatcatc
    16081 gtctctcatg aacaagaatt ttatcaagat cttgtgcaac gagtcattga gattgaacca
    16141 aaataaacgt ttgattgaat agttgaaaaa aaggagctgt gacaaaagtt ttgtcacaac
    16201 tccttcttct gaataaatgg tggccaatta gctgaccttc ggtattagct caaaaaacgg
    16261 caaaatatga ggagctattt ttatttggct attcttatta cttgatgcag aacagctttt
    16321 cacaacctct tttcgtctat tttttatttt cgagatttct ctttccttta aaaacaactg
    16381 tttgaaagaa gaacgcacat ccttgaaaaa caagcccgct aaccgttaca cctaaccagc
    16441 catactgctg ccacattgtc gtccctagca atgaaccagc cgcacctcca ataaagtaca
    16501 taaacataaa tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg
    16561 tttgattggc gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca
    16621 aaatggccaa atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa
    16681 gtcccatata cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg
    16741 cagcaactgc tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat
    16801 tgtaggcggg actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa
    16861 acatgaaaaa tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg
    16921 gcaaactttt aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg
    16981 gcattttcca gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga
    17041 tcatccgcca agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc
    17101 ccacgagtaa accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta
    17161 gtaccgcacc gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag
    17221 aagcgcatgc aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag
    17281 ataacgctgc cattcgaatg atcaattttg gacgatccac cacgtcccct aaaggaacta
    17341 aaaacagtaa ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac
    17401 ttgtgctaac agataaacta gctgctactt ttgttccaat cggctggatg taatacatat
    17461 tggcaacaac aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtt
    17521 ttttttcatt actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa
    17581 aagattggaa atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc
    17641 cttgtttttt cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac
    17701 ttgcaaccaa cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg
    17761 catacaacac agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag
    17821 gcaatttcat cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat
    17881 agcctaacat tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat
    17941 tcgtttcggt tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt
    18001 taccaagagc attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac
    18061 cagcaatgac tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca
    18121 atacgatcaa gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg
    18181 ccttactcgc tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc
    18241 gatagcccac taccagtatc agaatgattc ccaacgagat caatatcaat cggattattt
    18301 tctttttcat atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa
    18361 aacaaaaaag caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt
    18421 taacagttac agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt
    18481 tagatacgcc ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca
    18541 agcctaaacc agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg
    18601 cagttaattc tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag
    18661 ctacagctac aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt
    18721 cgttaagttc taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg
    18781 ccattataat ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa
    18841 gctgcatctc catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact
    18901 ggcgcttgta gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc
    18961 aatgctgtga tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct
    19021 aatgcttttg cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg
    19081 ttactgaatg caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct
    19141 tttttagctg cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca
    19201 cgaagttgtt tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact
    19261 actactgatg cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt
    19321 gcgataattg cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt
    19381 tgcactgaaa aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc
    19441 tattcacttc gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt
    19501 gctcaaccag tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac
    19561 tctatgccac cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg
    19621 aaattaaggc ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag
    19681 cttagcatgc taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct
    19741 aatatttaat tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat
    19801 cgttacattt ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc
    19861 atggattgct gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg
    19921 tacatggata tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt
    19981 tactgctttt gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt
    20041 tggtcctaat actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac
    20101 tacatcaaag tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa
    20161 atctgcacca gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt
    20221 ttgtgtttta ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt
    20281 tttagggtct acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt
    20341 tgtttctttt gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt
    20401 ttttaatgca tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg
    20461 gttataacgg ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag
    20521 ctgctgtctt agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt
    20581 caaccatgcg cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag
    20641 cgatttctct tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg
    20701 aacctttttc gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa
    20761 cgaatgtgaa tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt
    20821 gatcagctgt acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac
    20881 ctagtgcagg acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa
    20941 cgattttttc tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat
    21001 tggagatgca tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat
    21061 gtgcaaaaca atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt
    21121 tctgctattt ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt
    21181 tttcgttctc atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag
    21241 caaacaataa cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt
    21301 ggagaaaatg aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat
    21361 tggtccaagt agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat
    21421 atttggcgaa cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta
    21481 tcgggggcac ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga
    21541 tgaacgttta gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt
    21601 tcctaagagt gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac
    21661 acgaaagctt tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt
    21721 gaatggattc aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga
    21781 tgttccaggt atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg
    21841 cactatgaca gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga
    21901 tgatcctcaa gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt
    21961 aaattatttc gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca
    22021 agcaaaagct tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg
    22081 ccgttcccgt agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc
    22141 aatcaacgag ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa
    22201 aaaattagat gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc
    22261 tgtacgcaat gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac
    22321 accgactgcc ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct
    22381 tgatttgaca catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt
    22441 catcgcaaac aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc
    22501 tgcaagtgca atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc
    22561 agcacaagca gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc
    22621 aggcttagtt gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat
    22681 ctctgctgat atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc
    22741 tgcaatgtac caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg
    22801 cttagctgtt acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg
    22861 ataaagctcc ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga
    22921 gaggactaat tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt
    22981 catcgatcgt ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt
    23041 caaaaacaga tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc
    23101 caatcgcaac taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga
    23161 caccagagtc gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata
    23221 cttcaaagga cgcaggacct ccatctagtt gacgtccacc atgattggat acccagatac
    23281 catctgcccc tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga
    23341 taactggaag atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt
    23401 ttgcagctgc ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt
    23461 cgctatacgc agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt
    23521 cttcacggta accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt
    23581 ctactgcttt gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga
    23641 aaaactgcgg tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag
    23701 tgctgatgga aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt
    23761 tttcatgtgc caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa
    23821 ttccgaaaac agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga
    23881 ttttctttgt attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac
    23941 cgcgaatata gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg
    24001 caatgtttac aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc
    24061 cttctttcat cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca
    24121 tttactctca gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct
    24181 acttcttggt tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc
    24241 tctatttcat ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt
    24301 actgttccat cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg
    24361 gttataggaa tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca
    24421 ggcccctttg ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa
    24481 ggcgcgccaa ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt
    24541 cctaaatagc gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct
    24601 atgccgtagt tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac
    24661 tcgttatttt tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac
    24721 aaatctcctg ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact
    24781 gcttgctgat ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg
    24841 tagccgtgga aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc
    24901 gttttttctt tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac
    24961 gcaaacaaac tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt
    25021 ggttctgtca tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc
    25081 atatgatcga catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag
    25141 ttctgtactg gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc
    25201 gtcaacttct gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac
    25261 ttcgccaact tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat
    25321 atgattgact tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac
    25381 gaatcctgtc acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat
    25441 ttcaacaagt acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt
    25501 gacttcagtt tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat
    25561 actttgcgca cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg
    25621 caagacatac cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat
    25681 aaaaaaacct cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt
    25741 tgtggctagc gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta
    25801 cgtaaaacat caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga
    25861 gttgttttct gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt
    25921 tcatgagaca acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt
    25981 acaatattta caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga
    26041 ttttgtgtag ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat
    26101 ttacttctgc ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt
    26161 ttacttgtca atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta
    26221 atttgaaatt aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg
    26281 tatataagaa aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa
    26341 aaattttaga aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt
    26401 tccgtggaaa catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga
    26461 cgcttcctgt cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt
    26521 tcttcaaagt attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa
    26581 atcattttta tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga
    26641 gcgtagaaca aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg
    26701 ctgctattgc aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata
    26761 tcgaaaaaga cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga
    26821 aagtatgtga aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg
    26881 aaaatttgca aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct
    26941 ttcttttttc gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata
    27001 atacatcaat ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata
    27061 ggttgtccaa aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct
    27121 gatggtaaag aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg
    27181 caataaagct gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat
    27241 gataccaaaa ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa
    27301 tttacggtta aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc
    27361 tgaggataca ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt
    27421 tacaacgatt acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt
    27481 ctcctagttt ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa
    27541 ttataacaga cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct
    27601 taaacaatgt aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt
    27661 cataagaatt cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa
    27721 cttaaataaa taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag
    27781 caagcagctg aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa
    27841 tggatcatgc gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc
    27901 ctagacttct gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa
    27961 gtttctttca ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga
    28021 gtattaaaat atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata
    28081 tattgatcaa tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac
    28141 cggtattaaa aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg
    28201 atgctgagat tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac
    28261 agaaaacaat cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc
    28321 aggtacttga tactttctat cagatggaag tagaattccc agttgcttat attccagcag
    28381 gttctggaga tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc
    28441 agctgatttt agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa
    28501 taagtgaaaa aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg
    28561 tccatgcgac aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat
    28621 tttcgtattt attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg
    28681 tagatgcagg aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc
    28741 atcctttttt tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca
    28801 ttgattttgt cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac
    28861 ttatacagaa aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac
    28921 gtatcgtttc aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac
    28981 cttttgatat cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt
    29041 gtcagaagct acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg
    29101 tcacagtcct ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt
    29161 ttctttcttt acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga
    29221 cacaaccatt gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga
    29281 tcaagttatt attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca
    29341 tttctggcaa gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa
    29401 aaatatcttt gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg
    29461 aaaagctaat gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta
    29521 tatcccacga ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca
    29581 gcagcgagta actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg
    29641 gcgcactctg gtttcgttta ctgatctctt tgcgattaaa tgctagattg atgacgctga
    29701 aaccgctaaa aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca
    29761 acagcttttt catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga
    29821 gtgccatttg tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa
    29881 tcagtgtttg caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg
    29941 ggcgactctg tatcttgatc gtcggcatct ttcctacttc gacttgttcg gtaaagtctg
    30001 caggcagatg taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt
    30061 gtgaggttcc atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat
    30121 cgactacagg cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat
    30181 tttcaacatc aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta
    30241 tcagtaaatt cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa
    30301 cgcacccctc tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac
    30361 catagaagat tggtataaaa actagccaaa tcagtgtaga aataaagttt
//
LOCUS       DARBDN010000021        30116 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000021 DARBDN010000000
VERSION     DARBDN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.021"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(26..604)
                     /locus_tag="SCH06_001024"
     CDS             complement(26..604)
                     /locus_tag="SCH06_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEG1077621.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(681..1211)
                     /locus_tag="SCH06_001025"
     CDS             complement(681..1211)
                     /locus_tag="SCH06_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEG1077622.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1215..2075)
                     /gene="rlmB"
                     /locus_tag="SCH06_001026"
     CDS             complement(1215..2075)
                     /gene="rlmB"
                     /locus_tag="SCH06_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEG1077623.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2068..2463)
                     /locus_tag="SCH06_001027"
     CDS             complement(2068..2463)
                     /locus_tag="SCH06_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEG1077624.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2460..3872)
                     /locus_tag="SCH06_001028"
     CDS             complement(2460..3872)
                     /locus_tag="SCH06_001028"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEG1077625.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3869..4405)
                     /gene="cysE"
                     /locus_tag="SCH06_001029"
     CDS             complement(3869..4405)
                     /gene="cysE"
                     /locus_tag="SCH06_001029"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEG1077626.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4491..4730)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4727..6187)
                     /locus_tag="SCH06_001030"
     CDS             complement(4727..6187)
                     /locus_tag="SCH06_001030"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEG1077627.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6357..7514)
                     /locus_tag="SCH06_001031"
     CDS             complement(6357..7514)
                     /locus_tag="SCH06_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HEG1077628.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7548..8918)
                     /gene="radA"
                     /locus_tag="SCH06_001032"
     CDS             complement(7548..8918)
                     /gene="radA"
                     /locus_tag="SCH06_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEG1077629.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(8981..9508)
                     /locus_tag="SCH06_001033"
     CDS             complement(8981..9508)
                     /locus_tag="SCH06_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEG1077630.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9738..10544
                     /gene="proB"
                     /locus_tag="SCH06_001034"
     CDS             9738..10544
                     /gene="proB"
                     /locus_tag="SCH06_001034"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEG1077631.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10541..11788
                     /locus_tag="SCH06_001035"
     CDS             10541..11788
                     /locus_tag="SCH06_001035"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEG1077632.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11864..12208
                     /locus_tag="SCH06_001036"
     CDS             11864..12208
                     /locus_tag="SCH06_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077633.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12325..12651)
                     /locus_tag="SCH06_001037"
     CDS             complement(12325..12651)
                     /locus_tag="SCH06_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077634.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13266..14468)
                     /locus_tag="SCH06_001038"
     CDS             complement(13266..14468)
                     /locus_tag="SCH06_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077635.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14585..15100
                     /locus_tag="SCH06_001039"
     CDS             14585..15100
                     /locus_tag="SCH06_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEG1077636.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15299..15745)
                     /locus_tag="SCH06_001040"
     CDS             complement(15299..15745)
                     /locus_tag="SCH06_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEG1077637.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15792..17270)
                     /gene="msr(C)"
                     /locus_tag="SCH06_001041"
     CDS             complement(15792..17270)
                     /gene="msr(C)"
                     /locus_tag="SCH06_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEG1077638.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17624..18253)
                     /locus_tag="SCH06_001042"
     CDS             complement(17624..18253)
                     /locus_tag="SCH06_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEG1077639.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18237..18701)
                     /locus_tag="SCH06_001043"
     CDS             complement(18237..18701)
                     /locus_tag="SCH06_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1077640.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19188..20456)
                     /locus_tag="SCH06_001044"
     CDS             complement(19188..20456)
                     /locus_tag="SCH06_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEG1077641.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20687..21424)
                     /locus_tag="SCH06_001045"
     CDS             complement(20687..21424)
                     /locus_tag="SCH06_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1077642.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21491..22060)
                     /locus_tag="SCH06_001046"
     CDS             complement(21491..22060)
                     /locus_tag="SCH06_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEG1077643.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22188..23060
                     /locus_tag="SCH06_001047"
     CDS             22188..23060
                     /locus_tag="SCH06_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1077644.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            23402..24274
                     /locus_tag="SCH06_001048"
     CDS             23402..24274
                     /locus_tag="SCH06_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1077645.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            24271..26229
                     /locus_tag="SCH06_001049"
     CDS             24271..26229
                     /locus_tag="SCH06_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1077646.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(26561..27412)
                     /locus_tag="SCH06_001050"
     CDS             complement(26561..27412)
                     /locus_tag="SCH06_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1077647.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            27535..28002
                     /locus_tag="SCH06_001051"
     CDS             27535..28002
                     /locus_tag="SCH06_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEG1077648.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(28265..28747)
                     /locus_tag="SCH06_001052"
     CDS             complement(28265..28747)
                     /locus_tag="SCH06_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEG1077649.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(28847..29710)
                     /locus_tag="SCH06_001053"
     CDS             complement(28847..29710)
                     /locus_tag="SCH06_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEG1077650.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         8593 a         6373 c         5455 g         9695 t
ORIGIN      
        1 agaagctcat taagattttt ctaaattatt cctcattata aaatttcaag tgttttttta
       61 ttttgagttt tactctcccg taagcgctca ttacttgctt gtgatccatt gctaaacatt
      121 cagccatgtc tacaaaatca acgccttgca tataataatg aaaaatttta gcttctattt
      181 ttgaaaactg gatttcgcaa ttttcgattg cttcttttaa taaaagatgc tgaattgcta
      241 aaggttcttg caatgtgatc tctgctaaaa agtctggtcc ttctgtctct attttttggt
      301 cgattgagac ttcatctttt tgatcacgac gcttcagcgc gttctgcttc ctcaacagag
      361 aatagatttg attgcttata acgcttttat aataacttcc aaagctaaca cctttgcttt
      421 tttcgtaagt tctcaatgcc tgatataaag cgatccttgc ttcttgttcc caatcctcag
      481 aaacataatt tcttaaataa taggtgtttt tcaaacgtag taaaagtgga aaatattttt
      541 gatacagggc agcaaatgct tcttcgtcac cattacgtgc agcgcgcaat aactcctcag
      601 acataaaata attcctccat aaattcgttt atggaggaat cttatcatca atgattcatc
      661 gaactgatta gaacgatatg ttatttattt tttctcatta aatcgtccaa tttttgggac
      721 aattttttta actgctcttc attccatgga gaattacgtc ggaaatcaat aaaatgcata
      781 tctttatttt cttgggctat tgttttttcc gtttttttta tcgtcttata taattcataa
      841 gcagaagttc gtaatgctcc ttgggaaaag atcatccact gttctgctaa atcgcttgtc
      901 gccactgtca cttgtgtcaa acggtcattc agctgaccag cgattctctc gatataactg
      961 tcagccgttt cgtcttcttt cgtaaaaaca acatccaact ggtatttctt ataattttgt
     1021 tggatgcccg gaactagttg ggcatcgaag acaacgatga cttccattcc ttcatatttc
     1081 gcataatttg ataaacgatg taaaagagct tctcttgcat ccgccatttt gtcctgcttt
     1141 ttaagctgga caagttccgg ccacgaacca atcatgttgt agccgtctac aatcaacagc
     1201 tgttttttca tggtctactc cccctgacgt tgggaaaaag cctgatacat aagcaaacca
     1261 gcagcaacac tggcatttaa gctctggacg tgcccggtca tcgggatcgt cagcaattca
     1321 tccatttctt ttttcaatcc tggactcatt cctttgcctt cattaccaat gactaaagca
     1381 attgatcctt tggcattcca tttttggaag tttgtgccgg tcatatctgt gccaaatacc
     1441 caaaatcctg tttctttgag ctgttgcaca gcttgtacca aattcgtcac gcgtgcaaca
     1501 gggacatgtt cgactgcccc agtggaagtc tttgttacga taggtgtgat tccaactgct
     1561 cggtgttttg gtatgatcac accatcgacg ccacttgcgt ctgctgtccg taaaatcgac
     1621 ccaaaattgt gtggatcttc gatgctatcc aaaatcaaaa agaaggggtc ttcttttttc
     1681 tcttttgttc gttcaatcag ttggtcaagg gataaatatt cataaggtgt aatcgcaaga
     1741 acgactcctt gatgcacgcc gtgatcgctc aaagtttcta atttttgttt aggaacccat
     1801 ttgactggca cagcttgttc acgtgcgatt tctttcagtt cttctacttt ttctcctcgt
     1861 gaatcttctt gaagaaagag tttattccct cgcccttgtt gtagcgcttc tactgcggca
     1921 tggtgcccaa agacgaaatt atcttctaat gcttcttcat tttgatcaga aactgactga
     1981 tttcgtccag tttgcttttt atttgaatat ctattttgtt ttttgtcttc aaatccacgt
     2041 ttcgattgat gtttgtttgt tctttcttta cccatttttt tcaccaactt tctgaataca
     2101 ccagcggatc aattcttcca tccgctcggt ttgttttgtc aaatgcagat agcccatgag
     2161 cgcttcgaac cctgttgcga cccgatacgt cgtaacatca gcattttttg cgctcgtatg
     2221 gcttttagca tttcttcctc tgcgataata aagttcttct tcttctgtca aaagatgttc
     2281 ttccagcatt tgctgaatca aaaaggcttg tgcattcgca gaaacataat tcgttgccgc
     2341 acgatgcagc ttattgggtt ttgtttctcc ttgatcaatc aggtggtcac gaacatagat
     2401 ttcgtaaatc gcatctccaa cataagccaa ggctaaaccg ttcaattgtg tgtaatctct
     2461 catgcttctc ttctccatcg ggttccttgc ggtgtatctt ctaataagat ccctttttct
     2521 ttcaacaaat cacgaatttc gtcgcttcgg acaaaatcac gattgcttct tgcttgattt
     2581 cgttcttcga tcaattgttc aatctcttca tctaataact cttctgctgt aaataaaata
     2641 ccgaagatcg aaagccattg cgagaataaa gcttctcctt gtgccaagac agcggcagaa
     2701 actttcggct ggtctagata agtgttcagc cacttagcaa gctcatagac cactgtgatc
     2761 ccatttgctg cattaaaatc atcgtccatt tcttcgatga atcgctgttc taaattttct
     2821 aacaaagcga ttttatccgc atcatctgcc aaattctctg aggcagtttc ttggcggaat
     2881 ttcaaattgt caaacgtatt cttcagtcgt tgtaaattgg tggctgcttc tttcatcgtc
     2941 gtttcactgt agcggatcgg acgacggtat tgtgtggtcg ccatgaagaa acgcaagact
     3001 tgtggatcaa cgtttttgat catttcatgt acagtgatga aattccctag agatttactc
     3061 attttttcat cgtcttcgcc aatcgttaca tagccattgt gcatccagta attagcgaat
     3121 tttttccctg ttttcgcttc actttgtgcg atttcatttt catgatgagg aaattctaaa
     3181 tcttgcccgc caccatggat atcgatcgtt tctcctaaat gttttgttgc cataacggaa
     3241 cattcaatat gccaaccggg acgtcctttg ccccatggtg aatcccaaga aatctcgcca
     3301 ggttttgctt gtttccataa agcgaaatct aatgggtctt ctttttgctg ctgttcttcc
     3361 cctgtacgct gacttgctcc gacttccagt tcatcgatgg attggtcact taatttccca
     3421 taattttcaa atttacgggt acggtaatac acatcacctg aagattcata agcatagcct
     3481 ttttcaacca acacttgaat aaatgctaaa atatctggca tatgatccat gactcttgga
     3541 tgcagtgtag caggttcgac attcaacgct ttcgtatctt cttcaaatgc tcggatgaaa
     3601 cgatcagcaa cttctggtgc tgtaatacct aattcgtttg ctgtacggat gattttatcg
     3661 tctacatccg tgaaattcga tacgaaatcg actttatagc ctcgatattc aaaatagcgt
     3721 cgaattgtat cgaaagcaat ggtgctacga gcatttccga tatggatata attatacaca
     3781 gtcggtccgc agacatacat accgacatgt cccttttgta tagggatgaa ttcttctttt
     3841 tttctggtca atgtattgta gatttttatc attctgatct cctcactttt tctcctttga
     3901 ttcgaacgac ttttgctggt actcctaccg ctgtagcgtc gtctggaaca tctttcaaca
     3961 caacggcacc tgcaccgatt ttggcgtttt ttccgatcgt taccggtcct aatatctgcg
     4021 cattcgcaga gagcatggct ccttgtttaa cagttgggtg tcttttaccc gtttcttttc
     4081 ctgtgccgcc taatgttacg ccatggaata aaatcacatc gtcctcgatt tctgcggttt
     4141 cgccaatgac gattcccatt ccatggtcga tgaacacgcc agttccaatc gttgctcctg
     4201 gatggatctc aacaccagtt aggaaacgcc agaattgagc attgatcttc gccaataaaa
     4261 agagccggtg ctgatataaa aaatgagaga aacgatgcca aaacaaggca tgaaaaccag
     4321 ggtatgtcaa aacgatctca gctgtcgaac gtgcagccgg atcgtttctc tttgctgcat
     4381 caatcgctcg ggtaaaccaa ctcatgactt tccactcctt tcgtaagaat tttatgtagg
     4441 aaatcatctt cttataaaga aaagaagcgc cttttaaata agtttcctta tcaaaagacg
     4501 ctttccgcgt ggttccactt ttcttcataa tcaatgatta tctctgacag ctaacgcctg
     4561 ttatacgttc ttggctactt tgtttcctat aaaacagttt ttcctgtttt ctgtgtttcg
     4621 ccaagaccac tcccagaggc atttcggcaa ccattcattg ataccttgca ccacccggta
     4681 tctctcttgt aatgatcagc tgcttacttt tttctgttca tcgtgtttag ttcagtactt
     4741 gatttaaatg tgctaatgat ttttcacgac caagcaattc gatcgtttca ggcaattctg
     4801 gaccatgcat ttgtcctgat acagctacac ggattggcat gaaaagattt tttcctttta
     4861 cgccagtttc tttttgaaca gctttgatgg cagctttgac agttggagca tctactactt
     4921 ccatttgttc tagctgtgct ttgaatgcgt ggagaacagt aggaactgtt tcaccagcaa
     4981 gtacttcttt tgctgcttca ttcaatacag gatgttcatt gaaaaatagc gtagacagat
     5041 caacgatttc tgcagcatag ctcatttgag gttgatacag gctaacgatc ttcttcaccc
     5101 attcgattgt cttttcatct gggttttctg ctacacgtcc atcagcgatt agataaggca
     5161 gacacatgtc agtaaatgca tctagatcca ttgctttgat gtaatggttg tttacccatt
     5221 gcagtttttt cgcatcgaaa gctgcgggtg atttacttag gcgttttgga tcgaacattt
     5281 tgatcaattc ttggtgttcg aagatttcgt cttcgcccac aggtgaccag cccaataatg
     5341 caataaagtt gaacattgca tctggtagat agcctaattc gcgatattgt tcgataaatt
     5401 gcaagattga ttcgtcacgt ttgcttagtt ttttacctgt ttcactgttg atgatcaatg
     5461 tcatatgtcc gaaggttggt ggtgtccagc caaatgcttc atagatcatc agttgttttg
     5521 gtgtattggc aatatggtca tctccacgta aaacgtgagt gattttcatc aaatgatcat
     5581 cgaccgcaac agcaaaatta taagttggca taccatcgcg tttttggatg acaaagtcgc
     5641 caccgatatt atcggattcg aacgaaatag cgcctttcac catatctgta aatgcgtatt
     5701 ctgtattgcg aggcacacgg aaacgtacaa cagattctag accttgtgct tctttttctg
     5761 cttgttcttc aggtgtcaag ttcgcacatg ttcctgcgta atgaggcatt tctcctcttg
     5821 cgcgttgtgc ttcccgttct gcttctaatt cttcttctgt gcaatagcat ttgtatgctc
     5881 gattgctagc aagcagctga tcaatcagcg gttgatagat ttctttacgt tcagattgac
     5941 ggtaagggcc gtattctcca ggattttcag gagattcatc ccaattcatt cccaaccaag
     6001 caaggttttc caactggctt ttttcgccat cttcgatatt acgtttttgg tcagtatcct
     6061 caatacgaat aataaagtct ccatcattgt ggcgggcaaa caaataattg aataatgcag
     6121 ttcttgcatt tccaatatgc aggtgcccag ttggacttgg tgcatagcgt acgcgtactt
     6181 tcgtcatttt cttcctcttc tttcaaacta gactttgact aacagcaaaa attccgtcag
     6241 ttacggcttc tcaaatatca tttatttaaa gccactcagc acaaatttta ccttttctaa
     6301 ggtaaatagt aaagccaact ggttgaattt ccttaccagt tggctgaatt tcttttttat
     6361 tttgattgtt tagtcttttt ctctgtctct tttttattgt cgattcctcg tcctgcatgt
     6421 gcaggtttag caaagatcat gcgtccagca gctgtttgaa gggcacttgt tacaacgact
     6481 tcgatacgtt cattcatgta atgctgtcca tcttctacga caaccatcgt gccgtcatca
     6541 aggtaggcta ctccttgttg gcgttctgtc ccggctttta ctactagaac attcatcgtt
     6601 tcaccaggga tgacgactgg ttttacggca tttgccaacg cattgatatt aagaacaggt
     6661 acattttgga attcagagac tttattcaag ttatagtcat tggttacaat gacaccatct
     6721 aaaagcttag ccaatttgat caatttgctg tctacttcac tgatatcttc aaagtctcca
     6781 tcgtacattt cgacagatat accctcttct ttttgcaagg catttaggat atctaatccg
     6841 cgacgaccac gcacacgttt caaactatcc cctgagtccg cgatgtattg tagttcgtaa
     6901 agaacaaaat tagggatcat caaggttcct tctaagaatc cagtctttgt aatatcataa
     6961 atccgaccgt caatgatcac gcttgtatcc aagattttat atttatggaa attttctcct
     7021 gattttcgtt ctaacagttg actctcaact tgactagctg tttcttgctc gatttttttg
     7081 cttcgtgaac caaaaacttt cttccattct tcgattcgtg tcgttcccat tctcaatccc
     7141 agatagccta agatgatcat cagtaaaatc ggcaatacac tattgacgaa tggaatttcc
     7201 atattgtaaa gaggggtcga gatcacaaca cctaaagtca atccgatgat cgcaccgatc
     7261 gcaccgaaga gaagataagt caagctgacc tcacttagtt tttgttctac ttgtttgata
     7321 atagctgaga tatgtttggc caacagcaaa gataataaaa agaaaataag tgcgcctaac
     7381 aggctgttgg taaatgtatt attcagccat ccgtttgact gttgaccgat tgcctgccaa
     7441 gctgagggta aaaatgaaat acccaagctt gcgccgacaa tgatcatcag caaagtaatg
     7501 acacgttttt gcatcgtttt tcctccgttt cgacaatcat ttattagtta gcggaacaca
     7561 cgcttcaacg tttcagccaa agttgctact ccaactatct cgattccttt tggcgcttcc
     7621 cagttaccta agttgttttt aggtaggtat acttttgtga agccgagttt ttggacttct
     7681 ttgactcgtt gttcaatatg actgacacgt ctgatttctc cagtcagtcc aatttcaccg
     7741 atgaaacatt ccgttggctg tgttcctttt tctttatagc ttgaagcaat actgacagcg
     7801 atagctaaat caatcgctgg ttcatttaat tttaccccac ctgcagcttt taagtaagca
     7861 tcttgattct gaagaagcaa cccagctctt ttttccagca ctgccatgat cagagatacc
     7921 cgattgaaat caagacctgt tgttgttcgt ttggcatttc cgaacatagt aggtgtgact
     7981 aatgcttgga tctctaccaa aattggacgt gtcccttcca ttgccacaac gatagcagag
     8041 ccagttgcac cgtctaggcg ttcttctaag aaaatctgtg aaggattagc gacttcttcc
     8101 aatccatgct catgcatttc aaaaatccca atctcattcg ttgagccaaa tcggtttttt
     8161 actgctcgca aaatccgaaa actatgatgt tgttcacctt caaaatataa caccgtatcc
     8221 accatatgtt ctaacattct tgggccggcg atcgagcctt ctttggtaac atgaccgacg
     8281 ataaaaatgg ctatcccatt tgttttagcg gttttgagta gttctgcagt ggtttctctt
     8341 acttggctga cacttcctgc cacacttgtg atgtctggct gcgtcatcgt ttggatggaa
     8401 tcaatgataa cataatcagg ggagatatgt tcgatggcac gactgatttc gttcatatct
     8461 gtttcagcgt atagataaaa ttctgtgttg atacttccga ggcgttccgc gcgtaatttt
     8521 atctgctctg cgctttcttc gccggataca tataagactt ttccgcctat ggctgctaat
     8581 tgctgagaaa cttgtaacag caaagtggat ttcccgatac ctggatcgcc accaatcaag
     8641 accatagacc ctggcaccac acctccgcct aacacacggt tcagttcttc taattttgtt
     8701 ttgatccgag gttctttttt agggacgacg tctgcgattt ttgttggttt tgctttttct
     8761 cctgtcaaac ttgtccgagt tctgcggtcc gttgtatctt gttcgatttc ttcgaccatc
     8821 gtattccatt ttccgcaatt tgggcagcgt cccaagaact taggcgacac atacccgcaa
     8881 ttttggcaaa caaattgtac ttttgatttt tttgccattg taccgcctcc ttttatccta
     8941 atcatgagac attaaatcaa gcttaagtat ctttaacgtt ttatttactg gaagaaccaa
     9001 atccgccttg acgttgagca gtcgtttgat cttgatctgc ttttaaaaac ggcaaaaaga
     9061 tcccttggcc gatacgctcg ccttttttga tcactacatc cttgaaacca aagttggtga
     9121 attggaacat gatatggcct tcatttgcct cattattgta ataatcactg tcaatcacac
     9181 ctactccgtt tgtcaacact aaaaaccgct tcaacggatt gcttgaacgg ttagcaagct
     9241 gcaaaaattc atcttctccc atgtaagctt tgattccagt aggcacgagg gttggtttca
     9301 attgtttttc attttctgat acatcttttt tcaatccatc tgcgactgtt tccaacccct
     9361 ttttccagcc tgctttccag atacttggaa tcacgacctc ttctgctgct tcaaaatcat
     9421 agccagcagc atgatgtgta gcgcgctgcg gtagattgat attttgatct ttatatttag
     9481 aaataacttc aaatcctctt tttctcaccg gttttcctcc ctaaataaac tactcctatt
     9541 ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa ttctgctatc
     9601 ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac aaaaaaacta
     9661 ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa tgagtggata
     9721 tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt attgtcaaag
     9781 taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca atcgatcagt
     9841 tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta gtctcatcag
     9901 gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact ttgattcctg
     9961 aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat aatcaaagat
    10021 tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg gtagattatc
    10081 ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg gacacgatcc
    10141 ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg acaaaatttg
    10201 gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac cttttgatcg
    10261 tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc gaggctcaga
    10321 tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt ggtgctggta
    10381 gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg atatttgaag
    10441 caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt gatattcttg
    10501 caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact tgatgcaatt
    10561 aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa accgcaaaaa
    10621 tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga tcattgaagc
    10681 aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga tgcaagaccg
    10741 cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa aaattgcttc
    10801 gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg gattgagaat
    10861 cggcaaaaag cgcgtgccac taggcgtgat cggcatcatt tacgaatctc gtccaaatgt
    10921 cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc ttcgcggtgg
    10981 caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag tactggtcag
    11041 tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg aaactgcagg
    11101 acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg gagcaaaatt
    11161 aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta caggaaataa
    11221 tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca tcgtcaatgc
    11281 aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc attctgagat
    11341 cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg tctctttacg
    11401 tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag acacagattg
    11461 ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt tggatgaagc
    11521 aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga cagatagtta
    11581 tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg tcaatgcctc
    11641 cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta tctctactca
    11701 aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa aatatatcat
    11761 ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc ccgccttttg
    11821 ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg aaattttaat
    11881 gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag tcggtatttt
    11941 atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa aatggtcgca
    12001 gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta gttacatggt
    12061 tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt caatcgctta
    12121 tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc agctgaataa
    12181 aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag agtgccttga
    12241 agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg tcacagcctc
    12301 tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt cctcttcgtt
    12361 aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct catccatgga
    12421 caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct gttcccgata
    12481 cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac cttccgcatt
    12541 gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg aaaattcaat
    12601 gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca tctattatcc
    12661 ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc agtttcatta
    12721 ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt ccgaataaat
    12781 ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca tgagaaactg
    12841 ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac ctcttggtaa
    12901 acggcgttca atcagctgac cctcggtatt agctcaaaaa acggtaaaat atgagaagct
    12961 atttttccgt tttgtttctc taatacttag gataaaacgc tgattttaca acctctgtta
    13021 aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac
    13081 tatttttccg tttgtttctc taatactcag gacaaaacgc tgattttaca acctcctgat
    13141 aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa aaatatgaga
    13201 agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc acaacctctg
    13261 atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat acaacataca
    13321 ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat atgttcacca
    13381 atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa actatagctg
    13441 gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt caacagtgta
    13501 ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag gactggcata
    13561 gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc tgctaaaatt
    13621 gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga agcaatagcc
    13681 agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata gccaatcaat
    13741 aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa tgcgattagt
    13801 ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag gcctactttt
    13861 ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc gcaaaacatc
    13921 aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac cccaccgact
    13981 agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat tgctttttct
    14041 gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa taaagcattc
    14101 ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga taatccgcca
    14161 agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt caaaccgatc
    14221 cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat gtaactagta
    14281 aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt ttttaagatt
    14341 gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac aactagcgct
    14401 gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg attctccaat
    14461 atttccatcc ctttctctct attagcatca tacatgattt attttacatg tcaatatgca
    14521 catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga gaggtaggat
    14581 ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac cacgttctgg
    14641 gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc agatctatac
    14701 aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag acgagcactc
    14761 tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg aatggatcaa
    14821 agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct atgctttttc
    14881 gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac agctgaacaa
    14941 aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga aacaagaatt
    15001 tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac tccaatggtg
    15061 tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca gaacctttct
    15121 agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt tggaaaagaa
    15181 aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt ctagaactgc
    15241 attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca gtgttccatc
    15301 attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg atgatcaact
    15361 gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca gagaataatt
    15421 gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc accattccta
    15481 aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga tttactggta
    15541 gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa atgaaagcca
    15601 ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct tgatgcagcc
    15661 ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt gtaaaaatta
    15721 ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc acgaaaatca
    15781 tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc ttttatttca
    15841 taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa caaaatcgtt
    15901 cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc aataaaatta
    15961 gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc aatcgtcaga
    16021 cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc ctgagcaaac
    16081 cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg tctcatgaca
    16141 aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata tacttgaaag
    16201 cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc taataaggtt
    16261 gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga aaactgaaaa
    16321 tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg tcccatgatg
    16381 ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg tttcatctgc
    16441 tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt cgcattcttt
    16501 tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc cagtctgatt
    16561 tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt tttcttttct
    16621 tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc tcgtagctga
    16681 gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga aaactctcgg
    16741 atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa atagcgatca
    16801 tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag tcgatcaata
    16861 ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc ataagaagaa
    16921 agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg ctctgaagtt
    16981 tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt tgcttcagcg
    17041 agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt cccatgatcg
    17101 ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc attttctcct
    17161 atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag ttctagctgg
    17221 ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat atgttttaca
    17281 ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa aatctgtttg
    17341 caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac taaatcacca
    17401 aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat actccatcca
    17461 tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa aagttcgaaa
    17521 cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt accacacacg
    17581 attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg aacatagtga
    17641 tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt cctattgata
    17701 aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc aactgatctg
    17761 cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact aacatgaatt
    17821 gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct cttgaaaaac
    17881 tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt ggcatcttcc
    17941 ctgattcgta agcttggttg tagatttctt cgccatattc gtaacattgc atatcgccaa
    18001 aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg atcaaaggac
    18061 gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt ttcatattga
    18121 cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg tgtgggattt
    18181 tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt gaaaaatcat
    18241 ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca aagttgggta
    18301 ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa agccggggat
    18361 agcacggaac ctgtatcttt atggtccatt tcacaatgct tgattttctt ctgggctttt
    18421 tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg cgaaacatag
    18481 ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat ctgcaacttt
    18541 tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat gatctcgtat
    18601 ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg atcggctaat
    18661 ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc ctttctaata
    18721 attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa agtcaaagaa
    18781 tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag aaattttttg
    18841 tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat tattgattct
    18901 tatcaaacta tagaagatag ctcttctgca gtagataatt ttacaccgcc aaaaatttcc
    18961 gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta tgcttaaaca
    19021 gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac ggtgttcaaa
    19081 aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct gtttttgttt
    19141 ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta ataaccataa
    19201 aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc cttagcactc
    19261 aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata aattggcttg
    19321 gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt taaagagttg
    19381 atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta taaacggtag
    19441 acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca gcctacagtt
    19501 ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt atgacggtta
    19561 tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt cagattatag
    19621 gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata acgacctgtt
    19681 agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc ggaatagtag
    19741 taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg caatgattct
    19801 ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc attcacatat
    19861 tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc aaatagattg
    19921 taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat ggcttgagca
    19981 atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt tgaggcaata
    20041 ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc atagccagta
    20101 tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg cccatctgtc
    20161 aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc tgatgtactg
    20221 tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga aattgtattt
    20281 tctgagacag tagctgactg caaagtactt tctgtatcgt tttcaattcc tgtttctgaa
    20341 gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac tgttgtgttg
    20401 gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc tttcatcttt
    20461 tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa agtaaaagca
    20521 agtcaatgtc catatttaaa taacatttgt ttctttttaa taaatttgct ttttctgcat
    20581 aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat ggtcgtttga
    20641 ataactattt aacaagtaat tctctctgga tattatccgt tatggattat acttcctgtg
    20701 tcgtcggacg gataatcatg ttgctgacag acatccggtc tggcgtttct atcgcaaatg
    20761 ctacagcaga agctatatct tcagatgtta atccccattc tttttgcgct tcatgaagtt
    20821 caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca gctcctggag
    20881 agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct tccatgattg
    20941 cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca acatgtcccg
    21001 ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt ggaagtacgg
    21061 cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc cattcatcac
    21121 ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac aatacatcga
    21181 ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca aaatctctta
    21241 catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt gcttttaggc
    21301 gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat agcttcgttg
    21361 ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct gataaatcat
    21421 tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat ctcttatttc
    21481 atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg attcctgcaa
    21541 cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca atggcattct
    21601 cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca tttttcttga
    21661 tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga tggttcaccg
    21721 tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg ccacctaagt
    21781 caacgaacat cacttgacga ttgataaaga catttttccc tatactaata tgtttgccga
    21841 aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca ctaatgatat
    21901 tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc gctgctaaag
    21961 gctcttcgtt ttccgcttgg atctgatgga tcacttcaaa gagcggatcc gttactcgaa
    22021 tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct ccttttatcc
    22081 ttactttata acggacggct tatgatgtct aatacttata aaacatactt aactattcct
    22141 tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg gatattcgta
    22201 tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca gcaaaatctc
    22261 tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa gaacttggtg
    22321 tgacactttt cactcgaggc tcccgagaga tacagttgac ggattctggt cgatatcttt
    22381 attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat ttaacaaatg
    22441 acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca atctctttca
    22501 tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt catttatata
    22561 gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat tttggactcg
    22621 taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc caagatcgtt
    22681 ggggactttt gatacatcgg aatcatcctt tagcaaagca aacagtcatc catccgcagg
    22741 aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt caactagctg
    22801 aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac ttattgtaca
    22861 atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat gggatcatca
    22921 atacttatgg gacggaaaaa gtattcatcc cactcgatcc gccattacaa gcttcactga
    22981 atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt ttagatgtcc
    23041 taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt ttaacaacga
    23101 ataagttaag caaaagatcc aatgattaaa taacataagt ttcttaattt gttccttcct
    23161 tttatttctg ataattccag taaattacta taattataaa aaaagaattg acaaaacata
    23221 actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact agatcatact
    23281 aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg tctatttttg
    23341 tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa agggtgcgcg
    23401 catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg gtggacagga
    23461 aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt tgatttttga
    23521 tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt tgcaaaattt
    23581 acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg atcatgcgga
    23641 aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg accacattgc
    23701 tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt taagagaaat
    23761 cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt atctgacaaa
    23821 agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc atattcacag
    23881 cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga ttgtatctga
    23941 catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac cattttcact
    24001 gaattattca agactggtga atcatttacg actgcttcta caacgaaccc atgcgcaaca
    24061 atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc cagaaagcta
    24121 taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg cgatcacgaa
    24181 agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa tcgtacaaac
    24241 aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg aatgggacgt
    24301 tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg gatcggaaac
    24361 tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg cggtaacgca
    24421 gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat gtcagtggac
    24481 aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt aaatgtttta
    24541 aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga tccatctttt
    24601 gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc agctctttat
    24661 aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg caagcgtcta
    24721 gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact gctcgtatgg
    24781 cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt aggctggggt
    24841 ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt gcatcaagca
    24901 atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa atttttggct
    24961 tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc aatcatgatg
    25021 ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga aaacaaagca
    25081 aaaacagctt ccttgatgtt agcagcagct tttgcttcat tctttactgg tgtaacagaa
    25141 ccacttgaat tctcatttat gttcgttgct tggccattat atgtcttgca tgcaattttc
    25201 actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt tgcctttagt
    25261 gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca gccattgatg
    25321 ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa ctttgctatc
    25381 aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga tgacgatact
    25441 gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta cgctgcatta
    25501 ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg tttgcaagtc
    25561 aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc tggtatgaag
    25621 atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt cgttgcagat
    25681 gagatggcaa aactacatgg tggtgctgca acacgacctg cacaaacaaa caccgtggtt
    25741 aaaacagaaa catttgccgg tggaacgatc gaacaagata tttacgctat cgcaaatggg
    25801 aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat gatgggtgac
    25861 ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg tacgatcaca
    25921 aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat cgaagtcttg
    25981 cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt atatgtaaaa
    26041 gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc cgctattcaa
    26101 tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa agtccaaagc
    26161 ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc tgtttccaac
    26221 aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag gagctgagac
    26281 aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc caactccgcg
    26341 gtaataagtc cagccaaacg taacatatga agagctattt tttatttgac tcttcttatt
    26401 acttgatgca gaacagcttt tttacaacct ctgataaacg gtgttcaaaa accagtttat
    26461 cggtatgaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa tttttcttca
    26521 tactcaaaac taatcggctt tttcacaacc tctttataca ttattcctga tccaatattt
    26581 cttttaatgc tgcttcaaga gaagttaatg gttttcccaa tactttttct aaatcatcag
    26641 aggaaatagc taactgatcc tttttaatat catgttggat cgctaaaaac atgtcagctg
    26701 cttcttgagg gaatccggct tcttttagat tttcgacaaa cgctgcatca cttgcttcaa
    26761 taatttctaa ctttttacct gtcgcacgct ctaatgcctt ggctaattct tcatagtcag
    26821 ttagattgcc ggataattct aagatttctg gagagtcact ttctactagt acttttgctg
    26881 cagcttctgc atattcacgt ttcaatgccc aacctgtttt tccatttcct gcagcataaa
    26941 cgaattgacc agtttttaaa gcctgcccaa tgataggtaa ttcattctct acataccaat
    27001 tattccgtaa aaatgtatgg gaaatacctg aatccttaat cattttttca gtgaattggt
    27061 gatctggcgc taatacactg atcgagtgat cggcatctgc aaaacttgta taagcgatat
    27121 aagatacccc agctgcttgt gctgccttca ctacattctt atgttcggct tgacgatttc
    27181 ctggaacgcc agagacaaaa agcaatcgat ctattccttt caacgcttct ttcattgagt
    27241 ctaaatcatc ataatcacca atacgtatat taaatccagc ttctttcagt gcttctcctt
    27301 tttcttcact acgtactagt acatagattt cattttgtgg aaccatcttt tttaagaatt
    27361 ccagcgcata accaccaaaa cctccagttg ctcctgttac taaataatgc atatttgcca
    27421 ctccctattc tttttatttg ttaagattta cagctgtaca tttataaatt acacctttat
    27481 cataaagagt gtggtaagat aagtcaagca aaaaaaatga aaggatgaca actgatgaag
    27541 tattctctgc aatttagtga tgcaatccat gtacttgcct atattgaaat gtttcaagat
    27601 acccgatcac tttctagtga gatgattgcc agtagtatcg aaacaaatgc agcaaatgta
    27661 cgtaaaatca tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac cggaaaaccg
    27721 cagccttccc ttgccaaaag tccagatcag atttctttac tagatgtcta tcgcagcatc
    27781 gaaggtaata cacagcttat ccaagtcgat ccaaaaacaa atccaaattg cgtcgttggt
    27841 gcgaatatcc aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa ggcagaagaa
    27901 gaaatggcta agatcacact tgatagtctg atacataaaa tagccgtttt ggaaaaagaa
    27961 aaaagaccag aaaacacagg cctcgtagag agatttttat aattctctct actgtgcctg
    28021 catttttctg atcggaatcg tctacataaa ttcttttatt ctccggggga caaaagcctt
    28081 gtcatgcccc tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat gacgtcttga
    28141 taaacggtgt tcaagtagct gaccctcggc attagttctg aaaaatgcaa aatatggaaa
    28201 gctatttccc atttttcctc tctaatgctc aggtcaaagc gctactttca cgacctctat
    28261 attatcatgg tttattgact accggtatcc agatttctcc catatatttc ccgttggtaa
    28321 ctcccatttc gactacagca tttggacccc caacataggc gtaatcttct acttctctta
    28381 aaacatgccc aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc gattctgcta
    28441 aagcgattac aacaagatac gttccttttg ggaatgggat gattcgggta gtgtttggaa
    28501 catcctgact cgtttgaaca ccgacatagt acatcatttt cccgttatag ggttcgttga
    28561 ctgtaaagaa ataatgattt tcagcagctt gtttcaatgc atctattgtt ccattaccga
    28621 taactttttg ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc gtattgctac
    28681 tcttcaattc cacaccaata cccgtcaccg taaaatctgg tttttcttcg atcctatact
    28741 ttgccatttc tcccaccctt tctattatat taagttcatc ttacataaaa ttaaagggaa
    28801 atgacacgat tacgctcttt tttctaggga tatttttatt ttttaactat ttttttgctt
    28861 tcactgcaat ccaaatctca ctgtaaacat tactgaaatc ctctccccat tttgtaaaag
    28921 agatctcggg agcttcgact aactcataat ctgaagaagg aagccattct gcatagattt
    28981 tcccccaagt atcttgtaaa gtttggggaa atggcccttt attaggaaaa atggcccaag
    29041 tgtgttcttc tatagcaagc atttctaaat cagcgtacgg attttctttt gtcgtagcaa
    29101 agccaatcat gtgcatcaaa ctgccctttt cttccaagcg ggctccatca aatccataag
    29161 aaacgttgat tacttgattt ggatataaat ctcctaactt atgcatctct tccctttgag
    29221 tctccgtgat cgtctgcgct aacttttgta tttcttgatt gactccttca aatttgacag
    29281 gaactttttt cgccacacct gccacataaa actgttcttt cttttcgata cgaaattcca
    29341 tcgattttcc tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat ttttgtatgc
    29401 cgtatctgct gatttctgaa ggcagatatc ctgaccaatc acgaaaagct cttgaaaaac
    29461 cttcgactgt ttcatatcca tatctaaacg ccgtttctgt cactcttgat ccatctagga
    29521 gatcgcgatt agccaaagcc aatctacggt ttttgatata gtccattagc gacatccctg
    29581 caataaacgt aaagatgcgt tttaattgat attcagagat tcctgtattt tcggctatta
    29641 ttttatagga aagtccttct gtcaaatgtt cttcgatgta atcgatcaat tggttcagat
    29701 ctttaagcat atttatcttc ctccttgctt gcctttttat catattatca aagaaagtca
    29761 attacttgat gaatcaggaa ccaatttagt cagatgtaga aaatgttgta tggatctaaa
    29821 gaaaattctc aagcagcgtt tcgtaacgga taattggtat tatctgccta tctatgtttt
    29881 acctttagaa aaataaattt tggggaagac acattctaag taaacaaagc ggtaaaaata
    29941 tcttttattc ccttagttaa tccgcttact acctactgta caaagcaaat tgttgttcaa
    30001 actgctgatc agaacgctgc ttggattttt ctttgcgata catcatacct cttttatcaa
    30061 ttggaacaat tatttatttc taacaaaatc acttcatttt tgtcagataa ataaaa
//
LOCUS       DARBDN010000022        30005 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000022 DARBDN010000000
VERSION     DARBDN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.022"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            8..649
                     /locus_tag="SCH06_001054"
     CDS             8..649
                     /locus_tag="SCH06_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077651.1"
                     /translation="MIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGEIYQAEGLSAV
                     LHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTAAELQKQMRYQ
                     IDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLITMIH
                     RFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            708..1148
                     /locus_tag="SCH06_001055"
     CDS             708..1148
                     /locus_tag="SCH06_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077652.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1160..1828
                     /locus_tag="SCH06_001056"
     CDS             1160..1828
                     /locus_tag="SCH06_001056"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEG1077653.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1892..2515
                     /locus_tag="SCH06_001057"
     CDS             1892..2515
                     /locus_tag="SCH06_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEG1077654.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2571..2957
                     /locus_tag="SCH06_001058"
     CDS             2571..2957
                     /locus_tag="SCH06_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEG1077655.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3170..4561
                     /locus_tag="SCH06_001059"
     CDS             3170..4561
                     /locus_tag="SCH06_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HEG1077656.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            4908..5555
                     /locus_tag="SCH06_001060"
     CDS             4908..5555
                     /locus_tag="SCH06_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEG1077657.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    5684..5900
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5948..8593
                     /locus_tag="SCH06_001061"
     CDS             5948..8593
                     /locus_tag="SCH06_001061"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEG1077658.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            8903..10216
                     /locus_tag="SCH06_001062"
     CDS             8903..10216
                     /locus_tag="SCH06_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEG1077659.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            10206..10859
                     /locus_tag="SCH06_001063"
     CDS             10206..10859
                     /locus_tag="SCH06_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1077660.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            10914..11465
                     /gene="radC"
                     /locus_tag="SCH06_001064"
                     /pseudo
     CDS             10914..11465
                     /gene="radC"
                     /locus_tag="SCH06_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            11596..12681
                     /locus_tag="SCH06_001065"
     CDS             11596..12681
                     /locus_tag="SCH06_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1077661.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSEEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            12678..14570
                     /locus_tag="SCH06_001066"
     CDS             12678..14570
                     /locus_tag="SCH06_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1077662.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNMDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            14577..14954
                     /locus_tag="SCH06_001067"
     CDS             14577..14954
                     /locus_tag="SCH06_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1077663.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            15108..15890
                     /locus_tag="SCH06_001068"
     CDS             15108..15890
                     /locus_tag="SCH06_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HEG1077664.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(16016..16747)
                     /gene="erm(A)"
                     /locus_tag="SCH06_001069"
     CDS             complement(16016..16747)
                     /gene="erm(A)"
                     /locus_tag="SCH06_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HEG1077665.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(16805..16864)
                     /locus_tag="SCH06_001070"
     CDS             complement(16805..16864)
                     /locus_tag="SCH06_001070"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HEG1077666.1"
                     /translation="MGTFSIFVINKVRYQPNQN"
     gene            17256..17918
                     /locus_tag="SCH06_001071"
     CDS             17256..17918
                     /locus_tag="SCH06_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1077667.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            18153..18296
                     /locus_tag="SCH06_001072"
                     /pseudo
     CDS             18153..18296
                     /locus_tag="SCH06_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            18446..18646
                     /locus_tag="SCH06_001073"
     CDS             18446..18646
                     /locus_tag="SCH06_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEG1077668.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(18900..20579)
                     /locus_tag="SCH06_001074"
     CDS             complement(18900..20579)
                     /locus_tag="SCH06_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEG1077669.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(20581..20793)
                     /locus_tag="SCH06_001075"
     CDS             complement(20581..20793)
                     /locus_tag="SCH06_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEG1077670.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21186..22916
                     /gene="efrA"
                     /locus_tag="SCH06_001076"
     CDS             21186..22916
                     /gene="efrA"
                     /locus_tag="SCH06_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HEG1077671.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            22913..24673
                     /gene="efrB"
                     /locus_tag="SCH06_001077"
     CDS             22913..24673
                     /gene="efrB"
                     /locus_tag="SCH06_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HEG1077672.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            24768..24965
                     /locus_tag="SCH06_001078"
     CDS             24768..24965
                     /locus_tag="SCH06_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077673.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25118..25603
                     /locus_tag="SCH06_001079"
     CDS             25118..25603
                     /locus_tag="SCH06_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HEG1077674.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(25707..26300)
                     /gene="clpP"
                     /locus_tag="SCH06_001080"
     CDS             complement(25707..26300)
                     /gene="clpP"
                     /locus_tag="SCH06_001080"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HEG1077675.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            26480..27007
                     /locus_tag="SCH06_001081"
     CDS             26480..27007
                     /locus_tag="SCH06_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077676.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27098..27835
                     /locus_tag="SCH06_001082"
     CDS             27098..27835
                     /locus_tag="SCH06_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEG1077677.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            27839..28756
                     /gene="miaA"
                     /locus_tag="SCH06_001083"
     CDS             27839..28756
                     /gene="miaA"
                     /locus_tag="SCH06_001083"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEG1077678.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            28758..29987
                     /gene="hflX"
                     /locus_tag="SCH06_001084"
     CDS             28758..29987
                     /gene="hflX"
                     /locus_tag="SCH06_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEG1077679.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         9987 a         4909 c         6316 g         8793 t
ORIGIN      
        1 agatactctg attgagcgat ctacatttct atatgttcaa ttgcaggaaa ataaaacatt
       61 gctgcatttt tcaccagagt tccatctaga ggggctaaca ttaggagaaa tctatcaagc
      121 agaagggctg tcggctgttt tgcacttttt taaggtagaa ttggaattac cagtaaaaga
      181 ttatatcgag ctttctcttg aatcttggga tcgagcagtg gttgaactgt ttccagaagg
      241 tttaatgatc gatacaaacg atgggaagat ccatctgact gcagcagaac tgcaaaaaca
      301 aatgcgttat caaatagatg acgaaaattc tttttctatt tttagacgtc agcaaaagat
      361 tctaaaaagc tttttaaaag tgatcagtaa aaaacggaat ctgatcaaaa cgacacagct
      421 gttgaaaaaa tatccaggtc tgcttcacac gtctattcaa tttcctcaat tgattacgat
      481 gatccatcgt tttatacgta tgcaacagct accatctaag aagctgtttc ttccattgac
      541 ggacacattt cgagtagtca acagagaaga taaaaagaaa gtgattgtga ttgactttac
      601 cagaaatcgg aatgtccttc accaagttgc aatggaaaag gccaattaag gctttttctt
      661 tttggatttt tttgtcataa taaatattag atgatggagg agataatatg atgcaaacat
      721 ggttagaaag gctaatacga tttcagcaga actatcacaa acttatgcag ggaagatatg
      781 cgaaatttga tcagttgaat cgcggtctat tgatcgctgc gcttgtcttt agtttgctaa
      841 gtcgttggtt gccctataga atcggacaat tgttgttcat cgtctttttc ggatggatga
      901 tatttcgttt cctatcaaaa aaaatctacc ccagactaaa tgagaatcaa cgttatttga
      961 aatatcttga tagagtcaaa gaaaaatatc atcagataaa aaacaaaaag caagtcaaaa
     1021 tggatcgaaa aagttatact ttttttgagt gcccgaattg tcatcaaaag cagcgtgcac
     1081 ctaaaggaaa aggacgaata cgtgtgacat gcaaaacatg tggtataaaa ttcgaaacga
     1141 atgtttaagg gagaaaagaa tgaaattagt attattacgt catggcgaaa gcgaagcaaa
     1201 ttttgaaaat tactggacag gatggctaga tgtcgcctta acagaaaaag gaaaagaaca
     1261 agcagcagtt gccggtcaaa aaatgcttga agccggactt caattcgatg ccgtttatac
     1321 ctctgttttg aaacgtgcga ttcttaccgg acaagtcgca ctagaagaaa tgggtcagtt
     1381 atggcttcct ataataaaaa catggcgtct aaatgaacgg cattatgggg atcttgtggg
     1441 taaaaacaaa gataagatga aagaaatata cggaaaagat caagtaaaaa catggcgcag
     1501 aggatatacg gaagttccgc cgttaaccgc agaaaataga tttgaccgca gatatgatca
     1561 cttggatccg catttgatcc catacggaga aagtctggaa atgacagtga atcggatcat
     1621 tcccttatgg caagatcatc tagcaccaaa actaaaagat cggcaagatt tactagttgt
     1681 gggtcatggt aatagcatcc gagcactgac aaaatattta gaagatgttc ctgaagatca
     1741 aatggatacg atcgatatcc caaatgcaca accaatccag tatacattag cagatgattt
     1801 gacaattctg gacaaaaaaa tactttaaag aacaccttta tctaaaagtg agagatagaa
     1861 aaaagaagca aaggaatgga acaaaaggaa catgaaaaat tatatatggg actttgatgg
     1921 tacattgttt gatacgtatc ccgcaatggt agatggtgca tggcaagcac taaaagattt
     1981 tggtatcagt atggacaaaa aagaaatcta cttcaaaatg aaaaagtatt ctactagtta
     2041 tttgatcaat gaatcaaact tgaatgccag agagtttaat gaattatttc accgatatga
     2101 aaaagaaagt acggaagttt cccgtccatt tccagaaacg aaacaagtac tggaaatgct
     2161 aaaagacaac ggcggtcgtc atttcatcct gacccaccgt ttgacagaat caacatgggg
     2221 cctgttaaaa gaacatcgat tggcacatct gattgaggaa gtagtaggga tcgatcagga
     2281 ctttcctcgt aaacctgatc cagcatcttt aaattatttg atcgatactt ttcatttaga
     2341 aagaacagac acgatgatga tcggcgatcg tcgtttagat atcgaagcag ggaaaaatgc
     2401 aggagtcgct acttgtcttt acgacatcga tcattttctg ggtgagatcc cggcagatta
     2461 tgtggtagga aatctgaatg aaatccttac cttgcagagc atcattaaaa agtagtatcc
     2521 cctttcaaag gagatatgtt ataattttca taaaggagtg ataaaattat atggaaatca
     2581 gaagacaaaa agaagttgta gaagcatttc attatgatat gagattgccg aaccaagaag
     2641 tagaaacaga tttgaaagta ggcttctcgc ctttaaaaga aacgatcgaa aactatccga
     2701 aagaacatag catcgtagga gcacgcttag agttccgttt agtgtttgat acatatgttt
     2761 tatctggaag tgtgagtcag atcaatcata tcctcaatcg gaaaattgaa ggtcaaaatg
     2821 atgtcacaca agaagaagtg gacgagctag tagcaccgtt attcgatatc gtacgccgaa
     2881 tgtcttatga ggtgacagag atcgccttag atcagcctgg ggtaaaattg aattttcaat
     2941 cagaaaaaca agaatagaca gtaaaaacat acctgcgata gattaaagct atcacaggta
     3001 tgttttttta ttactaattg taagcaaaaa gaatgtcatt tcgataaaaa tcgtctaaaa
     3061 tataaaagtc actgaaaaaa attttttcag gaggatggtt gaagaatcat tctcgggaac
     3121 ctttacttcc ttcgatggac ttgtcattaa taatatgagg aggagaaaaa tgacaacact
     3181 catcacagtt ttagtggttc tagtttttgc ggcattatta tatgtgttct atcgtatgca
     3241 aaagcgccat acaaaatttt caacacgcgt ctttacagca ttaggagttg gtatcgtctt
     3301 tggcggtctg cttcaattga tctttggtgt agacgacaaa gtcgttactc aatcaatgga
     3361 atggatcggg attgtaggtc aaggatatgt atcattcttg caaatgctag ttatgccttt
     3421 agtgtttatt tcgatcattg gtgcattcac aaaaatgaaa gtttctgaaa agctagggaa
     3481 aattagtgcg actgtattga cttctttact tggaacaaca gctattgcag cattgatcgg
     3541 aattggttca acaatgctgt tcggactcca aggagctaaa ttcacacaag gagctgcaga
     3601 aacagcacga atctctgaac tggcaacacg tcaggaaaca gttgaaaact tatcgattcc
     3661 acagcagatt ttatccttta tccctaaaaa cgtttttgct gatttagcag gtagtcgtgc
     3721 aacaagtacg attggagtcg ttattttcgc ggcatttgtc ggaatcgctt atctaggcgt
     3781 gaaaagaaaa gcgccaaaag aagcagcatt cttttcagat ttagtcgaca gtctgtataa
     3841 aatcattatg cggatcgtga cgcttgtttt gcgtttgaca ccttatggag tatttgcttt
     3901 gatgacaaac gttttggcaa caagtgattt tgcagctatc gtcaatttag gtaaatttgt
     3961 cgttgcttct tacgtagcat tgcttgctgt tttgattgtc cactcactga ttttgattgg
     4021 tgcaaaagtc aatccaatca actatttcaa aaaagccttt ccggtattga gctttgcgtt
     4081 tacttcacgt tcaagtgctg gagctttgcc attgaatatc gagactcaga caaaagcttt
     4141 aggagtagat gatgcaacag ctaatttctc agcaagtttt ggtttgtcta ttggacaaaa
     4201 cggctgtgct ggcgtttatc cagctatgtt ggcaacgatc gtcgcaccag cagctggagt
     4261 gaatgtcttt agtttggaat ttattttgat gcttgtggca attgtaacaa tcagttcttt
     4321 tggtgtagct ggagtcggtg ggggcgcaac atttgcttca ctgatcgttt taggggcaat
     4381 gaacttgcca gtagcaatcg ttgggttagt tatctctgtt gaaccattaa tcgatatggc
     4441 acgtacagca gtaaacgtca gcggtagcat ggtagctggt atcgtgacaa gtgcacgcat
     4501 caaagattta gatcgcgatg tcatcaatga tgattctaaa gtgatcgatg tgaatgcata
     4561 gtcaaaaaga ggttgtgata gaagtggtca gctttaagaa ataagaagaa gtttcctaaa
     4621 aatagtttct caaatttttg tgaaatttcg gcttatttcc gagaagctac ttctgaaaca
     4681 ccgtgaataa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
     4741 aaatagttcc tcatatttta cgtttggttg agcttattac cgcagatgca agcttttgaa
     4801 caccgtttta tttgtctcac acccttttcc ttcctacttg taaccttgct cccgtgttag
     4861 aaacatgtta cactaaatat gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa
     4921 cagatacact gccaaaagca actgcgaaaa gattaccttt atatttacgc tacttgaaga
     4981 tgctggatga ctcaggtata agtagaatca aatcaaatga gttcagcgaa atcacccaaa
     5041 ttccttctgc aacgatccgc agagacttct cgcaattagg cgagctaggc agaagcggat
     5101 atggctatga tgtccctttt cttatcgatg tattcaataa tatccttaat actaaagaag
     5161 aaaaacgaat cgcattagta ggatatggaa atcttggcaa agcattgaaa cacaacaatt
     5221 ttagaagaaa tgaaaatcta aatatcgtgt gcgtctttga taatgatcca gcactgatca
     5281 atcgagtaat tgatggagaa atgatctatc cgattgatcg tttcgcggag atagccaaag
     5341 caaaaaatgt gacagtagca atctctacgg taccaagtaa atattcacaa tctgctattg
     5401 atgaaattgt caaaggaaat gtaaccgcta tacttaattt tgcgcctgac agagtaactg
     5461 tcccagctta tgtcaatgtt caatacattg atttgacaac cgagttgcag acgcttattt
     5521 actttgatga gaattactca gaagtttttt cttaggaaaa tttgagtagg cttattgatc
     5581 ttgcgagaac tcgtcgtaat tctttcaaaa attttttagt actaaatgaa gtggtttttt
     5641 cacgaccact tgttgactaa aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa
     5701 gaggagtaac tggcacattc attcttagag agagaactat ctgctgaaag gttctcaatg
     5761 acaaccagtg aaggtagctt gggagtttct gtcttgaatg gagtagagat agacgagtcg
     5821 tgatcgttaa ctcacttgag aggcaataat gattgattat tgcaatttag gtggtaccgc
     5881 gtaaatcata cgtcctagaa tacgaaagta ttttaggacg ttttttagtt taaaggagga
     5941 aaacagcatg acggaagaaa ataacctatc aacaaaatat aatccgcaag aagttgaagc
     6001 tggacgttat cagcattggt tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc
     6061 aaaaccttat tcaatcgtaa tcccgccccc aaatgttact ggaaaacttc atttagggca
     6121 tgcttgggat acgaccttgc aagatatgct gattcgtcaa aagagaatgc aaggatatga
     6181 tactttatgg ctgcctggta tggaccatgc aggaatcgcg acacaagcaa aagtagaagc
     6241 gaagcttaga gagcaaggga tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca
     6301 agtgtgggaa tggaaagaag agtatgcgag ccacatccgc gaacagtggg ctaaaatggg
     6361 cttatcttta gattacagta gggaacgttt tacattagat gatggattat ctgaagcagt
     6421 acgtaaagtt tttgttacct tatacgaaaa aggtttgatt tatcgtggtg aatatatcat
     6481 caactgggat cctcaagcac gaacagctct atctgatatc gaagttattc ataaagatat
     6541 cgaaggcgcc ttttatcata tgagctatga actagcagat ggatcaggcg tagtagaaat
     6601 tgcgacaacc cgtccagaaa cgatgttggg agatacggcg attgctgttc atccagaaga
     6661 cgagcgttat caagcgctca tcggcaaaaa agtgattcta cctttagtca ataaacaaat
     6721 cccaatcatt gcagatgaat atgtagatat ggaattcggg acaggtgtag taaaaatcac
     6781 tccagcacat gatccaaacg actttgaggt aggtaatcgt catgatcttc cacgcgtaaa
     6841 tgttatggat gatgatggta cgatgaatga actagcagga aaatatgctg gaatggaacg
     6901 ttttgctgct cgtaaagcaa tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat
     6961 cgatacgatg atccacagtg tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg
     7021 gctgtctact caatggtttg taaaaatggc gccgttagcg aaaaaagcca ttgataacca
     7081 agaaacagat caagcagtgg aattcttccc tccaagattc aatcaaacgt ttttacgttg
     7141 gatggaaaat gtccatgatt gggtaatctc acgacaatta tggtggggac atcaaattcc
     7201 tgcatggtat cacaaagaaa caggtgaaat gtatgtaggg atggaagcac cagcggatag
     7261 tgaaaactgg gtacaagatc ctgatgtttt agacacttgg tttagttcag ctttgtggcc
     7321 tttctcaaca atgggctggc cagatacgga aagcgaagat tataagcgat acttccctac
     7381 tagcacttta gtaaccggtt atgacatcat tttcttctgg gtaagcagaa tgattttcca
     7441 aagcttggaa tttactggcg aacgtccatt tgagaatgtc ttgattcatg gattgattcg
     7501 tgacgaacaa gggcggaaga tgagtaaatc attaggtaat ggaatcgatc cgatggaagt
     7561 aatcgaaaag tatggagcag atgctctccg ctggttctta tcgaatggtt ctgcaccagg
     7621 acaagatgtc cgcttcagct atgaaaaaat ggatgcttct tggaacttta tcaacaaaat
     7681 ctggaatgct tcacgtttcg ttatcatgaa tatcgaagga atgaccgtag aagagatcga
     7741 tttatctgga gaaaaatcag tggctgaccg gtggatcctt actcgtttga atgaaacgat
     7801 cgaacgagta actgagctat ttgatcgttt tgaatttggt gaagcaggtc gacaactgta
     7861 taactttatc tgggatgatt tttgtgactg gtacatcgaa atgagtaaag aagtacttta
     7921 tggagatgat gctgtttcaa aacaaaccac ccgtagcatc ttagtccata cacttgatca
     7981 gatcctacgt ttattgcatc caatcatgcc attcgttaca gaagaaatat gggaacatat
     8041 tcctcatcag ggaaattctc tagtagtggc agaatatcct gttgtacgtc cagagtttga
     8101 tgatgaaaca gcttctaaag ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa
     8161 tattcgttca gaagtgaata caccattgtc taaaccaatt acgttgctaa ttaaaacaaa
     8221 cgatgctaaa atcgatcaat ttttagttga aaatacaagc tatatcgaac gcttctgtaa
     8281 tcccgaagag ttgacgatat caagtgagat cactgcgcca gatctagcga tgtcagctgt
     8341 tctgacaggt gcagaaatct tcttgccgtt agcaggattg atcaatattg aagaagaaat
     8401 caaacgatta gaaaaagaac tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa
     8461 actttctaat gaacgttttg tttctaacgc gccggaagaa gtagtagagg cagagcgtgc
     8521 aaaagaaaaa gattatttag agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg
     8581 tactattcaa taagaataga aaaagagagt gtgaaatcag ctagctatta ctaaaagcta
     8641 gctgattgaa catcgttaca ggaaagagtt tgagcctcac tcttagcttc gattcataag
     8701 gagatgtgac ataaattttg tcgcatctct tttttagtct actcttatta tgtaggagaa
     8761 ggagggaggt ggatcatgta tcaagagtca ataaagtagt tgataaaatc gttcctctct
     8821 ctgtttcttt tctctttgtc atacttttat ttttcttatg tgttctattt gttataataa
     8881 aagagaaatg ggggaattgt tgatgacgat tgaagaagca atagaatgga tccatagtcg
     8941 attaccattt ggttcacgtc ctggccttga ccgagtcgaa gctttattag aagtggtagg
     9001 gcatccagag agaaaagtaa aaacgatcca tatcgctgga acaaacggaa aaggttctac
     9061 tgtagcttat ttgagaagcc tattagaaga ggctgggctg acagtaggta catttacttc
     9121 accttatatc gaaacgttca atgaacggat cgcaatcaat ggcaaaagca ttccagacaa
     9181 tgatttgatc cagcttgtaa aaaaatatca gccactgatc aaacaacttg atcaatttga
     9241 agcagtagct ggtattactg aattcgagac attaacagca atggcatttg attatttttt
     9301 gatgaagaaa gtggacgtag cgattatcga agttggctta ggcggcttat tggattctac
     9361 caatgtagct gtaccaatgc tgacgggaat aacaacgatt ggacttgatc ataccgaaat
     9421 acttggagat acaattgaag aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt
     9481 tccagtagta acaggaaata ttgccccaga agcttttact gtcatccaac aaacagctaa
     9541 agcaaaaaat gcaccgcttt atgtatacgg ggaaaattat aaaataaact atctgcatcc
     9601 tgatgagatg tggggagaag tatttgaatt ttttaatgaa ataggaaaga tccctcaatt
     9661 aaccactccg cttttagggc aacatcaagc tgaaaatgca ggagtagcca tcgaattgta
     9721 ttttgtttac tgtcaattgg aaaagctgcc tttccgagaa aaagatgttt tgaagggatt
     9781 gaagaaatct cgatggccag gaagaatgga gcgtttgagt aacgagccat tagttgtttt
     9841 agatggtgcc cataatacgc atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt
     9901 caaaggatat caaatcaaca ttttgttttc cgccttacga actaaaaatg ttagagaaat
     9961 gctagaacga ttgcagcaag taccaaatgt ccatatttat ttgacgacct ttgaacatcc
    10021 aaaagccatc gaattaagtg aagtatcaga tttagcaagt gagagagtat caatcgtttc
    10081 attgtggcaa ttcggattag cagatatatt ggaaaagatg acaaatgaag acgtattagt
    10141 tgtgaccggt tcactttatt tcatttcaga agttcgccat ttattaatac aattaggagg
    10201 agatcatgaa gtataatgca gtgatttttg acatggatgg tttgctgttc gacacagagt
    10261 tagtgtatta cgaagccaca caagtagtag cagacaagat gggttttcct tatgataaag
    10321 acctgtattt aaaattctta ggtgtttcag atgaagaagt atgggcgaat tatcatatga
    10381 ttttctcgga atttggcaaa acaagtgtac aaagattcat agatgattca taccaggaaa
    10441 cgcttgaacg tttttcgcaa ggagcggtac aaatgaagcc cggtgtgttg gaactcctct
    10501 cttttttaga agaacatcag attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca
    10561 ttgaactttt attgaagaag aacaatctgt ttgaacgatt tgagacgatt gtttctgcag
    10621 aaaatgttca acgagcaaaa ccagacccag aaattttctt gttagctaat cagaagctag
    10681 gtacagcgaa gaaagaaaca ttgattttag aagattcaca aaatggtatt ttagcagctt
    10741 ctgcggctga gatcccggta gtcatggtac cagatctgct tccaccatcc caagaattga
    10801 tcaaaaaaac agctggggtt gtttcttctt tacatgaaat ccctgcattg ttaaaataaa
    10861 aatccatctc ttttcgtatc ttattttaga taagatagaa aggagatgtt tttttgggaa
    10921 aacgattgat caaagaagta cctactagct ctttaccaag ggaacgtatg gaaatttatg
    10981 gcgcggaagc tttatcggat caggagcttt tggcaatctt actgcgtacc ggtcaacacc
    11041 cttatagtgt gatgtcgatt gctggaaatc tgttaaaaac gtttggagga ctggcctctt
    11101 tacgacaggc tactttgcat gagttagaag agattcgagg gataggacgc gtgaaagcaa
    11161 tcgaaatcaa agccttgatc gaattaggtc gacgaattca gacggatcat gaaagagcgg
    11221 ctccaccggt tcgtaccagc tacgaattgg cccagcaatt gattctggaa atgaaagatc
    11281 acaaacaaga acatttggtt tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa
    11341 aaacagtgtt catcggttcg ctgaatcagt cagtcgctca tcctagagaa attttccatt
    11401 atgctgtacg ttattgtgca gcaaggatcg ttttagcgca taatcatcct tctggtaatg
    11461 ttttaaccat agtataataa ataatagtag ttaaagtagt ttaagaggag atattaaagg
    11521 gatattttac tttaaataaa aattaacaag gtttataatt tgtagtagtt aaagtattta
    11581 aagaggtggg aacatgtgaa ggttcaaagg atagaagtgg agaataagcc gtatccattg
    11641 tatttattac tagataaaga ataccagcta atagaaccag taatgaaatt tattaaatac
    11701 ttagataata ctggtaagtc tcctaatacc attaaagcat actgctatca tttaaagttg
    11761 ctgtacgagt tcatggaaca gagaggtgtt attcttaatg atattaactt tgagttgtta
    11821 gcagacttcg taggttggtt gagatatcct tcagcatcaa atgtaattga tcttcagtca
    11881 aaaaaagcca taagagaaga aacgacagtg aatacaattt taaatgtagt tatgagtttt
    11941 cttgattatt taagtagatt aggagaattt aaatcaattg atgtatttaa acaagcaaag
    12001 ggaagaaatt tcaaaggatt tttacatcat gttaataagg gtagatacca aaagaatgtc
    12061 ttaaagttaa gggttaaaaa gaaacagata agaacattga gatcagagga agttaagcaa
    12121 attattgatg cttgtcatac gaaaagagat aaattaattt taatgcttat gtatgagggt
    12181 ggtttaagaa tcggtgaagt gttatcgctt aggcttgaag atattgtcac ttgggacaat
    12241 caaatccatt taacacctag agatgttaat gttaatgaag cttatattaa attaaggaag
    12301 gaaagaacaa tacatgtgag taaagaactt atgtcacttt atacagatta cttgatatat
    12361 gagtatagtg aggaattgga gcatgattat gtttttattt ccttaaaaga aggctatttt
    12421 gggaaaccac taaagtacca aagtgttctt gatctagtta gaagaatagt taaaaggact
    12481 ggaatagaat ttacatcaca tatgcttcgc cacactcacg caacgcagct aattagggaa
    12541 ggatgggatg ttgcgttcgt tcaaaagaga ttaggtcacg cacatgttca gacaacgtta
    12601 aatacctatg ttcatctttc agatcaggat atgaaaaatg agtttaataa atacctcgag
    12661 agaaaggagc ataagaaatg aatgcttcta gtaaaaggaa aattattagt cagagtgaga
    12721 ttagcaaaaa aatagctgta atgaatgaag aaatgcaggg gttttgggct aataatagtt
    12781 gggatataag aaaatgtcca catccttctg ccatagaatt aagtaagaat cctgctttaa
    12841 ggaatcgttg ggttcgtttt gaacgtgtta aaaatctgtg gttaagaaca gaattgaaat
    12901 atttttattt ttaccattta aacaatggaa tatggaatgc aaaaactgtc tggattagaa
    12961 aaggaacagt aattaataaa atgttagatt tcttagattt aaagtatcct agcattactt
    13021 caattactga agttcctatt gaaaaagcaa tgacggagta tagaacttat ttgacaaaac
    13081 ggggtgttag aattaccact actaattata agattactgc taatcaagaa aaaacacctg
    13141 taaaagctaa ttcctactat gttactaatc taaaacaatt tatggagttt tatgagaact
    13201 tttattttga tggagaggag tgggataaag acgtttggga tagacgtaac ttacctttgc
    13261 cagatgataa ggttaaccca acacaatatg aatatacaat taactttaaa gggtttcgga
    13321 atacatattt taaacaactt gtaaaaagat attgtaagtt gagattgaac atggatagct
    13381 tttcctatgt aagtgatatt gcccaaagac ttaaagagtt ctttaatttt ctggacatga
    13441 aatttaaaca agttcagaga gtacaccaat taacgagagt ggaaattgaa gcatatttaa
    13501 gtgaactaaa catgatggga ataaaaccta gtacaataac tgggaggatc tctatattgg
    13561 aaggactatt tagtaccctt cttaggctag aatgggatga tgttccttcc aaaatattaa
    13621 tttattctga ggactatccg aaaataccaa gagcaaaacc acgctttata gatgaattcg
    13681 tcctagagca attgaacagt catcttgata aattacccga atatatagct acgatgacta
    13741 tgattgttca agaatgtgga atgaggataa gtgaattgtg caccttgaaa aaaggctgtc
    13801 tattagagga caaagatgga gatttctttt taaagtatta tcaatggaaa atgaaaaagg
    13861 agcatatagt tccaatatct aaagaggtag ctttacttat taaagttcgg gaagataaag
    13921 tttcagagga atttccagat agtgaatacc tctttccaag aaaagatgga tcgccattaa
    13981 aacaagaaac atttagaggt gagttaaata aattagctta tgagcaaaat atagtggata
    14041 aatcaggtga gatttataga ttccatgccc atgcctttcg ccatacagta ggaacaagaa
    14101 tgattaacaa cgggatgccc cagcatattg tgcagaaatt tttggggcat gaaagcccag
    14161 aaatgacaag cagatacgct catatctttg atgaaactct aaaaaatgaa tttactaaat
    14221 ttcaggaaaa actggttacc aataatggag atgtgcttga tctagatgaa gataatgaag
    14281 tcgatgatgt agagcttcaa tggttcaaga aaaatataaa tgcacaagtg cttccaaatg
    14341 gttattgtag attgccagta gtagcaggtg gttgtccaca tgcgaatgca tgcttagatt
    14401 gcactcactt ctgtaccagt aagcaattct taccacagca cgaagaacag ttagagcgta
    14461 cagaagagtt attagccata gctaaggata aacaatggca aagacaagta gagactaata
    14521 gccgtgttaa agagcgttta gaacaaatca ttggaagttt gacggggtaa ttatcaatgg
    14581 ataaacaagt tagaaataca acagaaattg tacgtttggc gaagcagaaa tcaaaaaaga
    14641 caagggaaaa agtagacaaa gcgatttcta aattttcgat tgaaggtaaa gttattaatt
    14701 ttaattcaat agcaaaggaa gctaatgttt ctaaatcatg gctttataag gaacacgata
    14761 ttaggcaaag aatcgaatcc cttcgtgagc gtcaaataac agcaaatgta gtctcaaaac
    14821 ccaagaaaag ttctcgttcg gaggaaatcc ttattaaaac cttaaaaaga agagtaatgg
    14881 aattagaaaa agaaaataaa aaattacaga accaaattca aaaattatat ggagatctgt
    14941 ataataaaga ataattatta atctgtagac aaattgtgaa aggatgtact taaacgctaa
    15001 cggtcagctt tattgaacag tcatttaggt atatgtccaa tctagggtaa gtaaattgag
    15061 tatcaatata aactttatat gaacataatc agttacgagg tgaaatcatg agcaatttga
    15121 ttaacggaaa aataccaaat caagcgattc aaacattaaa aatcgtaaaa gatttatttg
    15181 gaagttcaat agttggagta tatctatttg gttcagcagt aaatggtggt ttacgcatta
    15241 acagcgatgt agatgttcta gtcgtcgtga atcatagttt acctcaatta actcgaaaaa
    15301 aactaacaga aagactaatg actatatcag gaaagattgg aaatacggat tctgttagac
    15361 cacttgaagt tacggttata aataggagtg aagttgtccc ttggcaatat cctccaaaaa
    15421 gagaatttat atacggtgag tggctcaggg gtgaatttga gaatggacaa attcaggaac
    15481 caagctatga tcctgatttg gctattgttt tagcacaagc aagaaagaat agtatttctc
    15541 tatttggtcc tgattcttca agtatacttg tctccgtacc tttgacagat attcgaagag
    15601 caattaagga ttctttgcca gaactaattg aggggataaa aggtgatgag cgtaatgtaa
    15661 ttttaaccct agctcgaatg tggcaaacag tgactactgg tgaaattacc tcgaaagatg
    15721 tcgctgcaga atgggctata cctcttttac ctaaagagca tgtaacttta ctggatatag
    15781 ctagaaaagg ctatcgggga gagtgtgatg ataagtggga aggactatat tcaaaggtga
    15841 aagcactcgt taagtatatg aaaaattcta tagaaacttc tctcaattag gctaatttta
    15901 ttgcaataac aggtgcttac ttttaaaact actgatttat tgataaatat tgaacaattt
    15961 ttgggaagaa taaagcgtcc tcttgtgaaa ttagagaacg ctttattact ttaatttagt
    16021 gaaacaattt gtaactattg aaaatagaaa gaaattgttc cttcgatagt ttattaatat
    16081 tagtgacatt tgcatgcttc aaagcctgtc ggaattggtt tttagtgaaa agaacacgat
    16141 attcacggtt tacccactta taaacaaaag atcgatactt tttgtagtcc ttctttgaaa
    16201 tcaatggttg atgtcgttca agaacaatca atacagagtc tacacttggc ttaggatgaa
    16261 aatatagtgg tggtactttt ttgagcattt ttatatccat ctccaccatt aatagtaaac
    16321 ccaaagctcg ttgcagattt tgcaatcttt tcgcaaatcc cttctcaacg ataagatagc
    16381 tatatttagc ctgactttca aaggtaattc ttttgacaat atccgtactg atgttataag
    16441 gaatattacc atatatctta tagtttatat gttttgggaa ggaaaatttt agaatatccg
    16501 tttgaatcac ttttatattc tcagaggggt ttaccgcttc tttagtcact tgacataagc
    16561 ctccatcaat ttctatagca gtaactgatc gactcatttt gactagctct ttggtaaaat
    16621 gtccttttcc tgatccgatt tctattacgt tgtcttgttt actgatattc gtgtgattca
    16681 atatttcttt tacatgcttt ttagaagtaa taaaattttg cgtgtcttta gggtttttct
    16741 ggttcattat aaccttctcc ttactggtta taatgaactg acattaagcg ttcattataa
    16801 ccaattaatt ttgatttggt tgataacgaa ctttattaat aacaaatata gaaaaagtac
    16861 ccatactttt atctcctttc catttttttc attatgaatg agataaagta atttctacta
    16921 ctgcgatact ggtgcacata attgaaacct ccttatgtaa ctgaatatga ttgtatcatc
    16981 ttttcatttt agaataaacc tttatatgta attttgcact tgacacttca gatggacgtt
    17041 ttcttcaaaa taatatgttt tgaaacttga taagagaagc cactgtcttt actaaaaagt
    17101 aaaggctgcg ataaaggaca gtgactttaa taaagttgca ctgttgtatt gtctttggat
    17161 aaaattgtct aaagggaagt tttatcccca acgaaaaaac atctaaagtg gtaagtaatg
    17221 aaagaatgtc gataaagtag gaatggggga tctttttgaa tacaatagaa tcacagtttg
    17281 ataaggttgc agaagattac gatttcgtga atgagctttt gaatgattat tcattctttg
    17341 tgtctaatat gtctccaaag aaaggcagag cattagatat cggatgtggc tcgggtttgt
    17401 tagtggagaa attagcaagt tattatgatg aagtggtagg gattgatatt tctaatcaaa
    17461 tgctcgatct tgccaaatct aaacgtcaac taacaaatac ggtctatctg aatatgaatg
    17521 cagaacaact taattttaat gagaagtttg attttattgt aagccgaaca acctttcatc
    17581 atttggatga tatagccagc gtaatacagc aaatgaagga actgttgaat gaggaaggaa
    17641 gaatagttat tcttgataat gtatctgaag tcgagacacc gcctacctat gtttataaat
    17701 taggggcaat ccaagagttt ttaccgcatt gtttcaaatt tggaataaaa aatgcgatta
    17761 gaatttataa tcacaacaca tctaaatcat ggcttgagca tttagcttca gataagtacc
    17821 tatctgaaca aaattattac gatttatatg aaaagttgtt gcctggatgc caattccata
    17881 aaatgggttg ggcaatgggg gttgtctgga caaaataact taaagctgtg gctttgaaaa
    17941 gttgaatttg tgattgtttt cagagctatc gggtgcttta gtataaataa caatgaataa
    18001 aaaatcagcc tgtatcttat gttactatta agtaatttaa gatacaggtt ttactatttt
    18061 tgaaataagt accttccact tcaaatacat gtattcaaag tgaaagtatt gatttaaatg
    18121 attcttttgt aatttactct tgataatatg aaattccatc gcagcaggat atgaatttta
    18181 ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac cacttgatca
    18241 tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag aagtaagttg
    18301 ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt ttgggaatag
    18361 aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt taaattagtg
    18421 cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt tcaacgctga
    18481 aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc acttctcagc
    18541 tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt tcgacgttga
    18601 agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt atctgtaaat
    18661 caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa aaatacctgc
    18721 cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta aataaattta
    18781 agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa tggcttctca
    18841 tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata acctcttatt
    18901 tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc tgtacgttcg
    18961 aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc tgaacagtca
    19021 ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc attgatcatt
    19081 tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc agccaagatt
    19141 tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc tgaaagcagg
    19201 tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc gatatacaca
    19261 tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc taaaacatcg
    19321 ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc tagagaagca
    19381 tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg cttcatcaaa
    19441 cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat gttattgatt
    19501 tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg attgacactt
    19561 gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg ctggatttgg
    19621 atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc tccttgagaa
    19681 cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg tgcatctaca
    19741 aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat ggcattttcc
    19801 atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc tgctgcttgc
    19861 tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc gatttttgaa
    19921 aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt tggaatctca
    19981 gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg agccatttta
    20041 tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc agtcgctacg
    20101 atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact atgggtcgtt
    20161 ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt gatctcatgg
    20221 agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa cgctaatgcg
    20281 agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat tccgccgatg
    20341 tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt ttgtatgatg
    20401 tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg gaatttgatc
    20461 ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt tttcccgatt
    20521 tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga aagtttcata
    20581 ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat gacttccttc
    20641 tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt ggcgagcgtc
    20701 tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag ggttgcgtac
    20761 ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat ctgcgtaaag
    20821 cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa gccacctggt
    20881 ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc tcgtttttgc
    20941 ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac aacaattaat
    21001 tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga aagaaaaaat
    21061 caatgtttat catcccgcta taatcataat gactttttta tgagagaagt gttctattaa
    21121 taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta aaaggagatg
    21181 agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg tttttcaatt
    21241 tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt ttagcacgta
    21301 tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa gggatattta
    21361 tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat tttggttcga
    21421 ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag atccaaagtt
    21481 attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt acaacaaacg
    21541 atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt atggcaccaa
    21601 tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc agtttgtatg
    21661 tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag gtgtctgaac
    21721 cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg cgggaaaatc
    21781 tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa aaacgttttg
    21841 ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg atggctgttg
    21901 cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc tggagcgggg
    21961 cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt atcgagtata
    22021 tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg tatccaagag
    22081 cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg attgtagaag
    22141 atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa aatgtaacat
    22201 ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt acagcctctc
    22261 caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg ttgatccaat
    22321 tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga gtagacgtga
    22381 gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa aaagcgctgc
    22441 tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct acgcaagaag
    22501 aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga aaaccagatg
    22561 gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa aaacaacgat
    22621 tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat gacagctttt
    22681 ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa gaaacgacag
    22741 aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca gataagatca
    22801 tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg ttggaaaaat
    22861 gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta gcatgaaaaa
    22921 aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg agacttttct
    22981 tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc catatgttac
    23041 aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa tcaatttttc
    23101 ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt gtatttcgca
    23161 attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg atttgagaag
    23221 agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa accagcaagg
    23281 aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt tacaacaagc
    23341 ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa tgatgtttta
    23401 tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga tctggatctc
    23461 aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt ctcttggtga
    23521 gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag tatatggacg
    23581 cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat actttgggtt
    23641 tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg cctatgctac
    23701 ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga tcgttgtcgg
    23761 tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg ggaacgtgac
    23821 acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat tcgagatttt
    23881 agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa cgattttagg
    23941 agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat taatccaaga
    24001 tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga ccggtgccgg
    24061 caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag gagcaataag
    24121 gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc tatttggtat
    24181 ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc gcttcggaaa
    24241 gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg tagatcattt
    24301 tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag acaatgtgtc
    24361 tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc ctaaaatctt
    24421 gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga ttcaaaaagc
    24481 aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt tatcgacaat
    24541 ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa aaggaacgca
    24601 tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc aatttgctga
    24661 ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt gttctctatt
    24721 cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg gaacagtttt
    24781 taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac gtctgtcaga
    24841 cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa cgcttggcag
    24901 cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat atagatgtac
    24961 aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg gcctgagcag
    25021 gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt attcaatagg
    25081 attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta tagcatcaaa
    25141 tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt atcaagctgt
    25201 tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc aagatggtac
    25261 aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga cggtaggaca
    25321 tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga tggggaccac
    25381 gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat cattagtaac
    25441 agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta aagtgatccg
    25501 tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt atgtcgagat
    25561 aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag catccataaa
    25621 ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta gataagagag
    25681 cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc catgacttca
    25741 tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg atctgtatct
    25801 ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt taagcgttcg
    25861 cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc ttgagcgccg
    25921 ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt accttttgta
    25981 ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat tgtttggaca
    26041 tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac tgaaccacca
    26101 ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa gaaaagcaat
    26161 tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat gatgatacgg
    26221 tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga ttgttcaatg
    26281 actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa atagtgtacc
    26341 ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa aggtcaaata
    26401 aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc agagaaacaa
    26461 aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag tgctgacagg
    26521 tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa ataaagaaca
    26581 gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc aattaaataa
    26641 aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg tcagctttga
    26701 tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat cattttcagc
    26761 gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga atatctccca
    26821 tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg cttataaagg
    26881 cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca atgaaaaaaa
    26941 agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag atgatgtttg
    27001 gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct ttcttttttt
    27061 cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct atgcccatcg
    27121 cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag ctgtacgagt
    27181 aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt tgatcgttat
    27241 gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag aaaaaacatt
    27301 ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc cagcagctaa
    27361 agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc gagggatgct
    27421 aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa aattagccga
    27481 aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc atttggattc
    27541 tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga tgagtacttc
    27601 tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac atccaaaaaa
    27661 tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa ttcgtgcatg
    27721 gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag atggaataat
    27781 aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta ggtaaaatat
    27841 ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc taagtgtgga
    27901 actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa tctataaaaa
    27961 tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc cgcatcattt
    28021 gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc attcaggtcg
    28081 acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg gtggtacggg
    28141 tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag aagcgaatcc
    28201 tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag cattatggaa
    28261 tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca atcaacgcaa
    28321 agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg cacctaaaga
    28381 agagccaaag caattgtatg attacctcat gattggatta gatacgaagc gtagtattct
    28441 ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag tagcagaagc
    28501 gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat ataaagaatt
    28561 tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag tcaaactaca
    28621 ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg atgcacagtg
    28681 gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa tcaaaaaatg
    28741 gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa accgaagcaa
    28801 accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat accgcatcag
    28861 gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa acgattatcg
    28921 gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg gatttgatca
    28981 tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct gttggtcttc
    29041 cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct cgttcgaaag
    29101 aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt ttagtagggc
    29161 aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca ggtgaaacaa
    29221 agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag aaagaattga
    29281 aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc gagatttttc
    29341 agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat ctattgacac
    29401 aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg actaagagat
    29461 ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc atccaagacc
    29521 tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa aatatggatc
    29581 ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag cagactgtct
    29641 taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt tacaataagg
    29701 cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta ttgatttcta
    29761 ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag ctgatggaac
    29821 taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta agcgagttga
    29881 gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa tatgaagtta
    29941 aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat tttatttttt
    30001 taaca
//
LOCUS       DARBDN010000023        27772 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000023 DARBDN010000000
VERSION     DARBDN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.023"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(250..1194)
                     /locus_tag="SCH06_001085"
     CDS             complement(250..1194)
                     /locus_tag="SCH06_001085"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEG1077680.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1490..2434)
                     /locus_tag="SCH06_001086"
     CDS             complement(1490..2434)
                     /locus_tag="SCH06_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077681.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2655..3869
                     /locus_tag="SCH06_001087"
     CDS             2655..3869
                     /locus_tag="SCH06_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077682.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3891..5906
                     /locus_tag="SCH06_001088"
     CDS             3891..5906
                     /locus_tag="SCH06_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HEG1077683.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5989..7362)
                     /locus_tag="SCH06_001089"
     CDS             complement(5989..7362)
                     /locus_tag="SCH06_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEG1077684.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7388..7672)
                     /locus_tag="SCH06_001090"
     CDS             complement(7388..7672)
                     /locus_tag="SCH06_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1077685.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7674..9689)
                     /locus_tag="SCH06_001091"
     CDS             complement(7674..9689)
                     /locus_tag="SCH06_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEG1077686.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9868..10170)
                     /locus_tag="SCH06_001092"
     CDS             complement(9868..10170)
                     /locus_tag="SCH06_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HEG1077687.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEVALAGTNSGETEDKEESLAGTN
                     SGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10259..11290)
                     /locus_tag="SCH06_001093"
     CDS             complement(10259..11290)
                     /locus_tag="SCH06_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1077688.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11497..12372
                     /locus_tag="SCH06_001094"
     CDS             11497..12372
                     /locus_tag="SCH06_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1077689.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12524..13366)
                     /locus_tag="SCH06_001095"
     CDS             complement(12524..13366)
                     /locus_tag="SCH06_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEG1077690.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13458..15335)
                     /locus_tag="SCH06_001096"
     CDS             complement(13458..15335)
                     /locus_tag="SCH06_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEG1077691.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15332..16753)
                     /locus_tag="SCH06_001097"
     CDS             complement(15332..16753)
                     /locus_tag="SCH06_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEG1077692.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16756..20145)
                     /locus_tag="SCH06_001098"
     CDS             complement(16756..20145)
                     /locus_tag="SCH06_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEG1077693.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20402..21793
                     /locus_tag="SCH06_001099"
     CDS             20402..21793
                     /locus_tag="SCH06_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077694.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21866..22513)
                     /locus_tag="SCH06_001100"
     CDS             complement(21866..22513)
                     /locus_tag="SCH06_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEG1077695.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22521..23207)
                     /locus_tag="SCH06_001101"
     CDS             complement(22521..23207)
                     /locus_tag="SCH06_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077696.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23213..24286)
                     /locus_tag="SCH06_001102"
     CDS             complement(23213..24286)
                     /locus_tag="SCH06_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077697.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24508..25182
                     /locus_tag="SCH06_001103"
     CDS             24508..25182
                     /locus_tag="SCH06_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1077698.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25187..26527
                     /locus_tag="SCH06_001104"
     CDS             25187..26527
                     /locus_tag="SCH06_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1077699.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26676..27662)
                     /locus_tag="SCH06_001105"
     CDS             complement(26676..27662)
                     /locus_tag="SCH06_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HEG1077700.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8095 a         5246 c         5044 g         9387 t
ORIGIN      
        1 atatgaatca ttgtatttgc cgttgcggaa ggatttttta attaaccaca gataaacatt
       61 gataacgatt cgcttattgt aatcaacaga ttaaatttca tatgttcata tgtacggata
      121 cattttcgga ccgattaatt ttaaccattc tgtttatttg cttacctatt agatatcaat
      181 aaaaaactgc ttaacagcta tttcagctgt taagcagttt taggattttt agttcatatt
      241 cattgtttct tataatacag tgttcaatac ttctcttaaa gcacttgttg atttgctgaa
      301 cattgctttt tcttcttcgt tgattgataa ttcaacaact tcacgaacac cattttcgtc
      361 aacgattgat ggcacacctg taaagatatc tttttcgtcg tattcaccag ttaaataagc
      421 agatacaggc aatacagctt gttcgttatt caagatagct tttacgatac gtgcagtact
      481 cataccaata ccatagtaag ttgctttttt acgatcaatg atctcataag cagcattacg
      541 gactttatca gcaatcacat ctaattcatc ttgggcaata cgatggtctt tttctacaat
      601 ttcaaacact ggtttaccac cgacagttgt atgtgaccat gcagcaactt ctgaatcacc
      661 atgttcacct aagatatagc cgtggacgct gcgtgggtca acttttaatt tcaatgcgat
      721 ttctttacgg aaacgagttg tatccaatgt tgttccagta ccgataacac gtgatgttgg
      781 cagaccagat tcgttccaag cgatatatgt caaaatatct actgggtttg aagcaacaac
      841 gataataccg tcgaatcctg atcccatgat ttcttttacg atttggcgca tgattgacgc
      901 atttgtttta actaaatcta aacgagattg accaggtttt tggttgatac cagctgtgat
      961 aacaacgata tcagcatctt tacattcttc atagccacct gaccatacag ccacattttc
     1021 atcgccccaa gccataccat ctaaaaggtc caatgcttcc ccttctgctt tttcttgatt
     1081 cacatcgatc aatactaatt cattagagat tccttggttg atcattgcat aagcgatact
     1141 tgttccaaca aaacctgtac cgacgattac tactttacga cttgtttttt tcatgaataa
     1201 acagctcctt ttcataacta tttgttactt tcatgaaaag tatagtcttg tttattcatt
     1261 ttatcaacat gttaattata atagttgtta ttataatttt tgatggaaac gaattcctga
     1321 atacgcataa cagataaatg acaaatgttt acacctatat cccctgataa tacaaccaaa
     1381 agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa cgatataata agacagcaat
     1441 cgcacctaaa acaattttcc ttcatatgct ttagtgaaag attttcttct taatgtttat
     1501 ttctccattc attgggagta catgttgaat acttcttgaa taatttgaat aaagaagtcg
     1561 tttgtttata tccgatacga ttagcgattt cttccaacga aaaactcgtt tcttgaatca
     1621 gttccaacgc aaagtcgaat tttttcttta gaaccagttc ttgaaaggaa gcatcaaaat
     1681 acattttcaa tttattacta agatagaccg gattgtagcc aaaatgagct gctgtttctt
     1741 ttaacgtaca agaagtaaaa tgcttatcga tataatctaa tactctaagc atctcatttt
     1801 ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa taaatgagtc aattcgatca
     1861 gtaatagtga tgtatagaga tttaacgaac ggatcttatg actgtatgta tcaaaataaa
     1921 tcaacagcat attttcaatc aaatgcgtca aacgacttgt ttttccgccg cgaaaatgaa
     1981 tgaattgtgt atgttcccct ttttcttttg atgcatttat caaaaaagaa gaaagtagat
     2041 tatttgtgct tgccaaatga ttcaatatct ctgtagataa ggtttcttct tttaataaga
     2101 tgttgattaa aatatcctct tgccctgtgt attcgattct ttgagtagct tctttatcaa
     2161 tgatcaccac gtcactttct tccatctcta tcctttctcc attaataatt tgtaaacatg
     2221 taccgctata catataattg atttcaacaa aatcatgtgt atgctcggga acttccgcat
     2281 atcgacggtg tttactgata tgaatatttc cctgttgaaa tagatcccct cggtggattt
     2341 ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt gatattcatt ccttgttcac
     2401 gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa tgtctaattc agctagttcc
     2461 aattgactcc ctcctttttg taagcggttt ctttcgctta ttagttcacg ctgtactgct
     2521 attatatgca aagctatttt tggtttcata aagactttct atggttggga catgaacttc
     2581 ctgtgattcc gctattgaga gaataaccac ttcatactat atttttgata agcgcttaca
     2641 aaaatgaaag gaacatgctt atgaataaaa agatgatgaa attttctctg ctgtcagtct
     2701 ctcttatttt gacttctgct ggtgcagtca cgtctgcaat tcccagtatg tcagctactt
     2761 atgccacgcg ttctttatct gctgttgaat tattaacgac tgctccctct tttatggtca
     2821 ctatttttgt tttgattagt agttttattg ctaggaaaat cggacaaaaa caaactgtga
     2881 tcatcggatt agtgattgca tcgatttgtg gtatcctccc cctcttctca caaagttaca
     2941 gtattgtctt agcttcaaga gctggactag gtattggctt tggattgatc aattctttgg
     3001 cagtcagcat gattgctgcc ttttatcacg gagatgaacg agcctctatg attggttttc
     3061 aaagtgcatt tcaaggattt ggtgcagctt taatgacatt tgttgcagga cagctagtac
     3121 agttcggttg gcaatatacc tttttagtct acgccatcag cttacctatt cttgtcttgt
     3181 ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca atcgcatggc acagccccaa
     3241 caagacaagt aatcaaaacg aatcctaaaa tgattagtta tggtattttt ctcttgctgg
     3301 tcatcgtggt atataatgct gtatcgatta aattagccac agtcctgacg acttattctc
     3361 taggaaacga aactaatgca gcgaatatct taacaatcat gcaattggca agtatggctg
     3421 ccggagtttg ttttggctgg cttcagacaa aagcacatcg ctatatgctt acactttctt
     3481 tactactgat gggaatcggc tttgtattga ttgccactgt gataaacctg tatgtgattg
     3541 ggtttggtgc gatcctaaca ggaatttctt tttcgttatt cattccttac ttattcaacc
     3601 aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa tacttcaatc ttattggttg
     3661 gcgctaattt aggtactttc attgcaccat atggtttgct ctttctctct tttgcttctc
     3721 ttgggagtaa aacacttgct gttttcgtca atggcagtat cttgctgttg attagcgcgc
     3781 ttattagcct tctagtagta cacaggacga atagaaagac agtgataaga gtagatgaag
     3841 aaataaaaga acaattgaca acaaaataaa tttgatggag gtcgtgtaaa atgacaaatg
     3901 aaaaacataa agatagatgg ctttggtatc ctggagactt tgagatccgc catggactgc
     3961 tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc agcgtactgg tacatggatg
     4021 attgccatcg gaacgtcaag tttaagagat attactttct tgatcaacct tccatgttta
     4081 aagtgacgat ccaaggagtt gggtatgtag aaattaatgg acaaaaacat ccatgtggaa
     4141 aatggctgac ttgtccagct ggtaaagcaa aaattcgtat ctttgtagga catacatcag
     4201 ggctaccagc gatgtttatc gagggagacg aagtaaaatc agatattggc tggacagcaa
     4261 gtaattttat tgaagaatat ccagctggct ggagtccgct ttatgtcgat atcgcaaaag
     4321 atccaaatca aatctattat caaaaagaat gcgtccatcc agtcactgaa acggagattg
     4381 gcggaggaat cttattcgat tttgggcgag cagtgaatgg ctgtgtagaa ctaatatctc
     4441 tggatgacca tatcgaatct atcactctat gttatggaga gtccgatgta gaagctatgg
     4501 atatcgatta ttgctactat aagcaaatag gaatgacaag aaaaatgaaa gctcgtaaac
     4561 gcgcttttcg ctatttgttt ataccagagg tttctactgg aatggttcaa cttcaagttt
     4621 ttcatgaatt tttatctctt tcgaaacaag ctgctttttc aagcgattct tctttactga
     4681 atcagatctg gtcagtatca gaagaagcct tcaagttatg tagtgatttg ttttttatcg
     4741 acggtatcaa acgagatcgc tggatttggt ctggagatgc gtatcaatca ttcatgatca
     4801 atcaatatct tttttttgac gaggaaatca ataaacgaac gatattagca ttaagaggac
     4861 aaaatgaaat caagcagcat atgaatacta tcgttgacta ttcgatcttg tggttgattg
     4921 gtatcgaaaa ccactatatg atgacgaaag actatgaatt tttacgcatc gtctacccta
     4981 agatgcaatc attaatgaga tacttgatgg agcaaacgaa tgaattaggg tttatttatg
     5041 ggagagcaaa agattggata tttattgatt ggtctgaaat ggataaagaa ggaacgcttg
     5101 ctgcagaaca agtcttatta ctgaaagcct atcattccat gatcacttgc ggagatatct
     5161 tagctgaaac atatggagag aacgaaaatt atcatactca tctctatcaa gaaaaatatc
     5221 aactattgaa acaaaaccta tttgactact tttgggatga agaacttggc gcttttatcg
     5281 attgctatga atctgggaga agaaatgtga cgcgtcatgc gaatattttc gctgttttat
     5341 tcgattttgc taacaaagac caacagcaat cgatcttaaa gaatgtctta ttgaatgaca
     5401 ctatcacaca gattactact ccatatttca aattctatga acaagatgct ttatgcaaac
     5461 tcggacagac gaatatcgtc taccaaacga ttcttgatta ttggggaggg atgttatctc
     5521 atgatgcggt aactttctgg gaagaatacg accctactca aacaggaaat gaaaagtaca
     5581 gtatgtatgg agatccttat ggaaaaagct tatgccatgc atggggagca agcccaatct
     5641 atcttttagg acgctatttt atcggtttgt atccaacaaa gccaggttat gaagaattta
     5701 tgatacaacc taatctagat tcatttgaaa cactgaattg tacgctacct atcaaagatg
     5761 gaaagatttc gcttgaaaaa acaaaagata agatcgtgat tacttctgat agaacaggcg
     5821 gaacagtgaa aatgaatggt aaaagttatc ctcttctagc aaaacagcca cttgtcttaa
     5881 caagctattc aaaaataaat gcataaaaca aaaaactgct tgcgacatat cagaagactt
     5941 taaatcttct tctgatattg tccaagcaat ttttattttg aagtttgctt aattctgttc
     6001 tttagaaaca atgtttgttc tttttccggc aaaaagaaag ctagataata cgacaagtaa
     6061 aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg tattctccta gtttcccaag
     6121 tacaagtcct ggtactagat aatcagtatc ggcaaatgta gaagaagcga ttttaagatc
     6181 tcctaatact ggaaggataa ataatggcag ccaactaatc aataagctat tgaaagcaga
     6241 acctaatacc gcccctcttc taccgccagt cgagttgccg aagacaccag aagcagctcc
     6301 gcagaagaaa tgtcctacta ccccaggaat gataactgta gtttgcaagc ctatcatagc
     6361 aaacatggat agtgttccta caaagaagct aacaaaaaag ccaattaata cagcattagg
     6421 tgcatatgga aaaacgatag gaacatctaa tgctggttta gaatcgggta cgagtttttt
     6481 agcaatccct tggaatgctg gaacgatttc tgccaacacc attcgaaccc cttgaaggac
     6541 gataacaaac ccagctgtga atgttccagc ttggatcagt gcaaagatta cagcgttgtc
     6601 tccattgctt agttctcttt caacaaatcc aggaccagct aacaaagcaa gtgcgacata
     6661 tacgatcgac atcaagagca tgatcgatac agtagaatct cgcaaaaagc tgaaactttt
     6721 aggaatcttt atgtcctctg tagaacggtc tttgtttcca aaaaactttc cgatccatcc
     6781 actagaagca taaccgatat ttccggtatg ccctaacgca acttgattgt ttccagtgat
     6841 gttcttcata aacggttgac aaagagcagg cgtaatagtt aatagtgttc cttcgaagac
     6901 cccgcctaat aagatcatcc acaaatttgc agtaaacccc gcgcttacta aaatgactgc
     6961 tgttagacaa gaaacataaa gcattgcttg acctgtaaga aaaatgaatt tatatcttgt
     7021 gaatctagca agtaaaatat tcacgatcat ccctactagc atgatcaaag cagtaggtgt
     7081 accgtattgt tgcaaagcaa tcgccactac tgcttcattg ctaggaacta ctccttgagt
     7141 atgcagagct gtttggaaca tcgaagcaaa aggggttagt gaattactga ttaaaccagc
     7201 accgccgatc agtactagga atccgacaaa tgttttgata gttccttgga tcacttctga
     7261 aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc aaagaaacga ggatggaggg
     7321 ctgactgacg attgacacaa acaaattcaa caatttatcc attgatagtt cctcccttga
     7381 atcattttta ttcttttgac aagatcttcg ttactttttc ttttacttct tcgctgtcaa
     7441 tgatcgattg caaaggtacg agcttttcat caggtataga agttagcgta tctttcaaag
     7501 aatgctcaat gaagaaataa tcagccatat cgctagatac acttccaaca tccgtatgac
     7561 ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag tgcttgtttg atgttcatct
     7621 ctaccataaa acttgttcct aatccacttt gacatactgc aaaaattttc atatcattcg
     7681 tctccttttc ttatgatcgc taatatttct tcttttgttg atgcgtgtaa taaatcttga
     7741 agattttgtt tattagaaag tagctttgtt aaatttgcca aagcccgaag atgtgcctca
     7801 ttatcgatag cagctaaaca gatgaacaaa ctaatgggat gggctggatt atcaagcaga
     7861 tccacaggtt gttgaagttt cagcaaagac atccctactt cgtttacgcc atcttctgga
     7921 cgagcatgag gtaatgcgat gtgatcgcca atatggataa acgcaccata ctgctccacg
     7981 cgctcgatca tagctttgat ataactttct tctattttat tttctgataa tagcggctgt
     8041 gcggcaaatg tgattgcttc ttgccagttt tttggttgat ccgataattg gatcatttct
     8101 tctgttaata attcagatag cataggacgt tgatcctcct tcttttctaa aagtttgttc
     8161 attttacgat ttaatacttg atagagcttt tcttcgtcta cgccttcttt taattcgata
     8221 taaggcagta gcgccgacaa caattcttgg gcagaaggca ttgaaaatcc tggtatcagc
     8281 caatctcttt gtacttgatt gatcagctga tttttttcca agtcagtcat gattggatgc
     8341 agaacataga gagacttttt cttatcagta agtgtgagag gtacagtaga aaaaataata
     8401 tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg aattagtctc tgtaaaaaag
     8461 atcatcggga ataattgctg aagttcactt tttaagatca atgaagagct aatgccactt
     8521 ggacagacga tcacggctct tatttttcta tttctttctt ctgcgtccgc ttttctgatc
     8581 tctccgccaa atagtatagt gaaaaaacca atctcttctt cagggatgct cttccctatt
     8641 cgtctttcta acggaagtaa tgcttttctt gtcatttcgt agatggaagc atattgatgc
     8701 ttaatttgat cgatcatcac attaggtaaa taaaaagaat aggaaatacg aaaataggca
     8761 gggaccaagt gataaaagac attcatcaat aattcacgaa acgaagcaaa ttctacggcc
     8821 atcaggaatt ccatgcgatg gatgacttct gaagaacatt ccagcaaaaa atcaagtgca
     8881 ggctcctgga catctccttc aacgatcgat gctaagcaaa gagagaaaaa tataatctcc
     8941 gaattttgat gttcggaata gccaaggcca gtcaatactt gtcgactaat gtcagtgact
     9001 gcaagagaag ccaacagttc agcatctttt accagttcca tggatgtttt tccaattcga
     9061 atggttgtca aactcaaata ataagctaat tcatccattc gatttggtgc gaatcgaaga
     9121 tctgatagtg aaatcgtttt atctagcaaa tctctaactt tggcgtaata atcaatggaa
     9181 agggttgcgg ttaaatacgt gagcccaaat cttccagcaa gtgactgcat caaacgagca
     9241 gtgcgatttt ttgcttctct tcttaatatt gcttctgacc ctagcagcct aaaaccagtt
     9301 ttcctagtat acgacagctg acaatcttcc acttctaatt catttcttat ctttttgata
     9361 tctgacagga ctgtcccttt agaaacctga agaaaatctt gaaaatgaaa aacagaaaca
     9421 gacgttgcag tcgaataaac catcaaataa agaagatctc ttcgctcttg ttcggtatac
     9481 acagcttcaa atcgagtaat atccaaaaat ttttctgccc agtcgattgc tcggaatttc
     9541 tttatacgga tacgggtatc atccacatat tcggcaaaag gagttaattg tttgatcgcc
     9601 tcgcttgtat ttacttcgat gatctctgct gctttttcta gactgatttc tcttggtgtt
     9661 ttcaggagat aactaatttt gtagttcaca gcgctgttca cctcctactt atattctagt
     9721 atggtagcgc ttttaaatcg aggggtgttt ggtacaactt acagttggat tttttttacg
     9781 actgtaccga acgatttcta tcgaatggat acagaaaaaa agcaggtgac caaatgtctc
     9841 ctgcttttat gaattgattt cgtccgatca atgatgatca tgtttatttt ttgaggtcag
     9901 ttcttcaaat ttttctttga catcttcaac cgctttttcg atatcttttt caaagtgatt
     9961 gggctcatta ggctttgttt cctcttctac agaatttgaa ccagataaag ctgtttcttt
    10021 attttctgtt tcaccagagt ttgtgccagc taatgattct tctttgtctt ctgtttcacc
    10081 agaattagtt cctgctaaag ccacttcttc tgttttaggg gccattgaac ctcttaatcg
    10141 tttgtgtttt tcaccgtcat aatttgtcat gttggttcct cctagtagtt ctatactttt
    10201 tcatcgtaca ataagacagt ttatgcgtca aaaaacaaac ccgattctta caaatatgtc
    10261 atatttttcc ttctgattct tgaatgcttt tgattccttc ttccaaaatt ttcatttgta
    10321 agattgtttc ttcatctttg atgacttttt ctgcgccatt aactaatgtc tcgtaaatcc
    10381 cttcgtagac acggctgtaa tcaccaacct cggaaattac tttttcttca tgataactcc
    10441 cttgttcatc tatataggtc aatacaccat aatgttcggg caaatcgata ccaaagtctt
    10501 catgatcagg catgtaaaac attttcagat gttcttcttg tcgatctttt gtttgtttca
    10561 cgaacatccc tttttttccg taaacgacga aacttggacg ttctttgatg cggaaataac
    10621 tggattttat cgaaattttc atatttccat agaaaaaatc cagatcgaag taatcattca
    10681 ttcgtccttt ccctaaaagt tgacgtacat catagctgat atcatctggt tcgccgaaat
    10741 aagaaagaac ttgatctact gtatgacaag catgtccata taaatagctg ttcgcagtag
    10801 aaaattcatg cgtattttct ggtacttccg gtctgaaata atcataatgc atttctactt
    10861 ctaaaatatc ccctaatttt ccgctttcga ttactttttg gactgtcaag aagtcagaat
    10921 cgaaccgtct gttttggtaa cattggataa atagaccttt ttcttttgct aatgcaaata
    10981 actcttctgc ttcctttgac gtttctgcaa aaggtttctc tactagtaca ttcttaccat
    11041 gttcgagtgc catttttcca tattcataat gaaattgact aggtgtagtg atgacaacta
    11101 attggatctc aggatcatcc caaagatcag acagctgatc agtatattcg atgtcttcga
    11161 atgttttcca cactggttca gatggggaaa aaattttttt gatattgatt ttgttcgtaa
    11221 gttttcttga aaaaggcaaa tgatagcgat ttgtactctt tccattgcca agataagcga
    11281 ttgtaagcat gagtggtgcc tccttttatt gatgttttca gtatatccta gaaaagcgca
    11341 gaaagtattt ataatagcta ttctggtaaa aaagttcaga aaaacacttg ttatcattcg
    11401 gtttggtgaa attaatgttc aaagtaagga taaaaatcaa aaagatagta gcggaaccaa
    11461 gtgtttatca gtaagataga atttggaggt cagatcatgc ttattgaaga aaaactaaca
    11521 aaacaagagt tgtttaccac gacagagaaa cggattgtcg attacatccg taggaatatc
    11581 gaagctgcag tctacatgac gattgaagaa ttagcaaaag ctacgtatac ttcccattca
    11641 gctatcattc gtttatgcaa aaaaatggga ttcagcggat ttaaagaatt ccgtttcgag
    11701 ctggggcggg aagttcatca attgattgct cagttcaatc aaacgattga tcctaatttt
    11761 cctttttcaa gtgaagatag cactcagcaa attgcaaaga aaatggcgga tttatcgatc
    11821 cagtcaataa aaaaagcaca attgcagatt gaacatgaag atttagatca aatcggtaaa
    11881 gtattgaaca aggcacagcg aatctttctt tttgcaaaag gtgattctca aatcacggca
    11941 aggaaattcc agaataaaat ggtcaagttg aataagtttt tgatcatggc tgaagaatac
    12001 agtgattctt cttggaatgc agccaatttg actagcgagg attgcgccat ttttattagc
    12061 tacagcggtc gcatccatca ttatgaacga ataatgacct atttgaagca tgtagaggcc
    12121 cctaccttgc tgattaccgg aaatcagcat tcagaaatgg ccaaacaggc tgatatgtgt
    12181 cttgttatat cgcaggagga atatgatttt gctaaagtag cgactttctc ctctcaaatt
    12241 gccttcgatt acgtattaaa tacgttattc tcagtgatat attctcaaaa ttttgaagag
    12301 aatatccgca acttgaaaaa caaacaagaa ttgatgcaaa aaggccttct taaagaatat
    12361 cggaaaactt aagaaaagat cctcatttag taataagaaa gatagtgttt gataggctct
    12421 ctttgatatc atcataaaaa caggctgaag ttttcttttt caaacctcag cctgtttgtt
    12481 tacggaacga ttcgaataga tatattatag aaatgaggaa tagctaactt ctgtttctta
    12541 ttttgaacga ttgacgaaaa agatatataa gaaggaggaa aatcagtata catgcagcta
    12601 acaatccata caggaaaaat cgtttgttct cggatacttt ctgtacttct ttttgaactt
    12661 cttttgcatg ataaggaacc cggtgccctc tgacaagtaa gcgatgactg ttgaccatat
    12721 aaggtgtaca agttaggagt gtcacgaaat cctgcccttt ttcgattctc agatcttttg
    12781 tatcagtcgg ttctaccgtc ttgatctgat cgacttgata agcgagtgtc cgtccattga
    12841 tttcgatata gaaagaatca cctaaagtca gtttcggtaa gtctgtgaac aactttgctt
    12901 gaggcagtcc tcgatggctg gaaataacgg catgtgtatt ttctcccccc gtaggataag
    12961 acgttccttc caataatgag gcaccttttt ctagcagcac agtattcgtt tcatcaaaaa
    13021 ttggcaaatg gacattgatc tcagggatcg tcaaaatacc gatcgtatgt ttctcaaaat
    13081 aggttctatc ctttttcgca ggttcttttt tcttagtaaa gggatctgca cctggatttc
    13141 caccttcttt tgctaattgc tggtttttct ttgtcatgtt ttcttggatt ttagccatga
    13201 cttcttcatt ttctttgacc gcttgttgct gataatgaga gatgatctgc tgatccagat
    13261 aattattcag cgcgtcgcta acaaatggat aagctagtat ccctattcct gagagaagca
    13321 agaaaagcat cagcagatct agaagtttcc ttttctttgg tttcatttgt gttctccttg
    13381 tgatgactgt ttgataataa aagaaaaagg agcatttgcg taatccgctg ctcctttttc
    13441 caattcttgc aaaaagacta aatctgactg tgcttgcgtc tagcaaagta cagtccagca
    13501 atcagtagaa ggactactcc tgcaccgata tacacataga ttcccttacc gcctgttgaa
    13561 ggaagtgtac ctttgtgttt atttggtatt ttttcaggag aaatcaactg tcctgctgtt
    13621 acataagatt gttcatcgat agtaaatgct acacggtttg ttaatggaac atatttttct
    13681 ggcgctttcg tttcttccag atagtacgtg ccatatttta gacctgtcac atcgattaaa
    13741 ccgttacttg tggttgtaaa aaccgttgct gattctttcg ccgataccca gctgacggct
    13801 tttgtggatg ggtcgatcga taaatatttc gctgtgtcac tatcttgatc acgaacgacg
    13861 aattctgctc cagcaagtgt ttggtctgat gtaacgtcac catctacttt aacaaatcgt
    13921 ttgcccccag taacgacatc gactgacggt ggtgtttgat catttgtatg cccgttatcg
    13981 acatttgctt ggttagaaaa tcctttggtt ggatctgctt tttcgttcaa atgcatatag
    14041 taaacgaatt tcaatgtacc gccaggagtt aatgaaggaa tataattcgg atcaactgaa
    14101 accgtgaatc cgtctgtttg ctcagtgaca gaataattta ctgggtcgat ttctttattt
    14161 ccatcatata aggcataagc atacgttcct gaagaatcat tatcaaatgt taaagcagcg
    14221 tcatgagtat cgataagttt gaatgttgtg tacttgtttt gcgttccttc tttatcagcg
    14281 atacctaatg ggatattgac agaaatctca tattgaattt tttcaccgat tgcgacatct
    14341 tttccattca attgaggtgt tgttttatca actttagacg tatcattttt gatggtcttt
    14401 tctactggtg tttggctatt tgccaggatc tcaaaaggcg tgattgtttg cttttcaatc
    14461 atttccgcat tatcaggagc ttttacttct tctaaattat attttccaac ttctaaatga
    14521 ttaacgatca actggccttt ttcaatagat gcctcggcaa agtcattgtt gccgatgtca
    14581 taagaatgac cagtaatgaa atgtttggct ttggtttgat cagttgtcca agtgtacaat
    14641 ccatctgtga cactttggat gtattttttg acgcttggtg ttccttcttc tttagaaata
    14701 ataaattctg ctccatttag tgcttcgttt tcggcagtac cgatttttgt aactttcaac
    14761 gttccatcat taccgactgt atttttaggg tagagatgga tagtatctag ttcttctgtc
    14821 ccgtatttat aagagccatc tgcttgtttg atcatctcat atacagggaa agctaaaacc
    14881 atgtttgcgg cagctgacac tccgtctttt ggttcttctt tgatcgtgta gactgcatct
    14941 ttcccatttt gttttttagg taaagataaa gtgacatttc catcagcatc tgtcgttcct
    15001 gaagcaactg gtgtaccagg agtcaaagac tggactgctt gttttgctgc atccacggac
    15061 gctcctttat ctcgttgcgc ataaaattct tgagtgacgt tataaactga aaatgaaata
    15121 tcggctaatc cttggtattg atcgaattcg ctcatttctt tcccgctgtt ttggattaaa
    15181 ggatcgggta aatcagtcat tttcttttta tgaaggatga cttgagctgc tgtctcctct
    15241 gcaaacactt tttttgcgcc gaagctgttt gtgagtaatg gtaaaataag gaaaaggact
    15301 cctaacataa cgtttatttt tttatgattt ttcatttttt cactcctgtt ctttttttga
    15361 taaacaacca gattgcaaag cttgcgaata ccataccaac aacgcctaaa agtgtatttt
    15421 tcgtttcgtt tgtttttgga agaaatggac ggctattttc ttttttattg actactttca
    15481 atatactgtc cgcctcttta tcctcagaaa gaaaagttga aatggtaaac ggaatttctg
    15541 tttcacttaa aatataacca gaaggtgctt cgatctcttt taatcgataa cttcctgttt
    15601 tcaacccgga aattgaaaaa gcgccatttt tatcggaaat caggtgaagc gcatctgatt
    15661 cgttctttgt ccacttgtat ccgttggctg tttgctggag gtaatttcct gctttgtttt
    15721 taataaggaa tactgcgcca gctaatcgtt tatctggttt atttgtctcg attttgacaa
    15781 attgcttact ccctgtatat acagagactt tctttgtact gacaccaaaa ccaaaatcca
    15841 gtgttccgtt gttgttgatt tccttgttcg cctgtgctgt actgcttagc tgcatctgat
    15901 aagaaatggt cagttttttt ccagcatatt tttccaacga agggatcgaa aataaaacat
    15961 caaatccgtg aggtttcttg tgtatgacaa agccttctgt cagcttttct ccattcgatg
    16021 aaatcgttaa actattaggt aaaaacgtta atgcttcatc cgcactatct gacaattcga
    16081 acttttgata gtcaaggata tttacaggaa ttgtcgtatg caaggaataa gtgatttttt
    16141 caccaatcgt aaaatcattt ctaggctctt ctaatacctt ctcaaaaggt ggatcagggt
    16201 agtcgttttc ttcattttta ggatacaaat ggatagttga aagtttttga ttgttttgtc
    16261 catgtacagg aagaacaact accatattct ctgccttttc tttgacgact tctggtactt
    16321 tggattcaat gaaaagatac gctttatctc ttttttcttg atctttagcg gccagagaaa
    16381 aagaagcgat accatcttcg ttgttaagag ttgtagttgt tgcttctgcg gtaaacatac
    16441 cggaagacgc accgtttttt gcgatctctg cttgtgcttc ttctaccgtt ttgccctttt
    16501 cccgtagatg gtaaaaagaa tctgtgacat cataaacttg gaatgtgaca ccatttaatc
    16561 ctcgatacgt ttgtaataaa gctttttctt gtccgtcatt tggatgattt ttcggcagtt
    16621 gcccgtttgg gaaaagcaat ttgtgtaaag taatctgaac catttctgtt tctgtttctg
    16681 ttgctacctg agtaaaagct ggtttaaata gtaacaagaa gagacacata ctaagccaac
    16741 caagtttttt catatttagc tgccccctct ttcttttttc aaaaaaagat accaaataga
    16801 aaacgcacaa ccaatcatcc ctactagata gattcctaaa cggccaattc ctcccgtttc
    16861 aggtaatggt acttttgcct gattcgtgat gtctaaagaa atctggttgt ttttggctcc
    16921 tggtgacaga acagattcat gatcttgtcc atccacttga attgacccat cttcgtgtat
    16981 aactatagta actggctctt ttagaccttg gtatccttct ggtgtaaaag tttcggtcag
    17041 cgtataagtt ccaggtttta aattttcgaa tagaaaggta tctgtttctt gtccatcttt
    17101 tggcgattct aagtccattt ctggtccctg cagtctgaat tttgctcctt ttaatgtctg
    17161 tccgttgtct tcttttttgt gtaccgttag atcaaacgct tttagtcgat tttgatgagt
    17221 gagcgtccat acattatttg tcatctcggt attttttccc gtgtaaatga tttttccata
    17281 tttatcgatt tggaattcat aatttcccgg cgaagtatca tatccggcag gaccagctgt
    17341 ttcaacgact cgatatttac caggtgtgag tgaatcaaaa ctggcaagac ctttttcatt
    17401 cgttgtttgg ctgtcaattg gctgataagt accatttgct tcttttttct gtagggaaaa
    17461 tgctgctcct ttaagattta tctctttgtc cgtcccttgc atcgcatact tacgtactgc
    17521 tacaggaact tcaacaaaag gattttcaat agtcaactgg atcgtatcat cggaagtagt
    17581 gactgttttt ccatcaatgg ttaccgtacc atcagaagcg atcttgattt cccaagtagt
    17641 ctttttgctt aatccatgcc cttctggagc ttttgtttct gtcagcgtat aggtcatttc
    17701 tttttgcaat ttgacatttt ctggaagaga ataggttccg tcgccatgat ctgttagtaa
    17761 agtatcaata gaatctcctg ttaatttgaa aacagcgcca ataagatcct tttcacctgt
    17821 agaggaattt ttcgttattt tcaagtttaa cggtgtgaat tgtttagtat ttttccatgt
    17881 cattgcatct atttgttgag aatcgtatcc tggtacaggt aattctttga ttgtttggta
    17941 actgaatgct tgaccttgat tattgtattg aggtagtgat aatatctctt gataactttc
    18001 tccgctattt gcagataatt tgtcaatgtc tgcacgttcc cacgtatttg ttgtatcttt
    18061 agctggttta atgattcgaa tatatccgtt tttccaagct gcagcatttg tcgtatgttc
    18121 ccgttgaatc tcaaaagtaa cttgatctgg acgatcagct agattgttgt caaattcttc
    18181 ccataacttt ttgatgtgaa gactgactcc gggagcttta gcagatggta taccgaattc
    18241 agctaattca ttggtatcaa tgtttggctg gaaagttgtc ctgccgttca tttgatacca
    18301 gaaatttgga tggaagtcct cattttctgt ttggattctc acttggtaat ggatttggat
    18361 ttcttggtct tttcctaaat agatctgatt gctcttgatg gtatttcctt ctatggaaat
    18421 agatggagtg accgttgtag gacttgtccc cacactcttg actgaaagtg taccaggctg
    18481 ataaatgaat ggttctgcga ttggatcatt tatttgtcca ttgcttacag ttgctgagat
    18541 ctgtacagct tttttggcta ggtattcaga gatatctgtt gcatgatcag ctgattcata
    18601 gtaaagatcg cctttttcat ctgatgaaac catttgtcgc atacgagact ctacttctgc
    18661 ttttgagaga ccagctgccg gatcgctttg aagttggatg ccaagaccat gtatttcgat
    18721 tcctcgttct ttgagtgcca tcgcttctcc gatggttgcg ataaacgtac tgtcgattct
    18781 tctggataga ttgttttggt caggtgcatc atagattctt gagattagag aagtatttcc
    18841 cggccgatct tgcgtattag aaaactgagt tccgtaataa ttgctgcttg attgtgcgtg
    18901 tacccgctgt actttatagg aaaatgttgg tacaccatcc gtcagcaaaa cgatcacttt
    18961 tttatgtcca tttggaacgg atagcatgct tcctgcatct cttagtgctt tttgtgtaaa
    19021 agtaccacca tttgtccgtg aaggtgtaat ggattttact tgatttttca ctgaatcaaa
    19081 tgaacccatc tgtactgcac cgttactgta gctatatcct tcgcttgagt agccgacata
    19141 tcccatattg attttgtctg tgataccgct atctgctaaa gtatcgacaa aacgatcgac
    19201 accaatcttt acttcaccga tccgattatt gtcgttcata cttcctgacc agtctacgac
    19261 caatacgaga tcaagaggcg tgatatcttt ttgtacattt ccacgagcat tcaaataaac
    19321 atcaaacaat ccgggtgtac ttgtttcctt tgcatacttt cgtatcgcat agtctgcttg
    19381 attaccggtt cctccatatt cgatatacga atgggtccga tcattaggat ctccattcca
    19441 agaatttata ccatcccatt gatttgttcc gtttttattg ccttgatgat caagaacatt
    19501 tgtatttcct gtaggttgcc aactggcttt aggataagtg ccctgatcat ctgttgtata
    19561 ttctgtagga atcgtttgat tagatggcac actcacagct ggcaaggata atgtaggcaa
    19621 tgtaaatggg ctgacagaat tttcgttttc ttttgatgat tcttcttcta tttcgtctgg
    19681 ctttggtact gacacatctg tatctttctt attttctgtc tcatcaataa tgtcatattc
    19741 tttattatcg acgatcagct tgtttgcctg gctgtggtaa agtgctggat cgattggaaa
    19801 actcagatcg atagtttgtt tagtgtttga tgagatttcc aacgtaattt tcccgctatt
    19861 tacctgataa gcatagccat ctccttcttt tctttccaca tcacttaagt aattttcgac
    19921 tagaccaatt tctttttcta tcttttcagc actggtgtta ttcgcattta gcttgatgtt
    19981 cagtgctttt tttccagact gatccgaaat gacttcagct gaaattgttt ctaaaactgt
    20041 tggatcatct gtagtgtctg ctattgcaga taatggcaca aagtttgata aactcaatat
    20101 tatcagcatg aaaataactt tcagtttctt ccctgtggtc gtcatttttc ccctcctttt
    20161 tctttttttc tgttttgacg tgaatagtga aaattattaa aataaacagg cgttacataa
    20221 ttttatttat tttaatatga taattattat acgaagggcg ctaaagggaa tcacaccaat
    20281 tttcatacca attggtttca tttatgaagt tgattccttc gattaatgag cgtttcattg
    20341 aaagaaaagg gttgagggag aaaaacatat gatcaggttg ttggaaggaa actatagaaa
    20401 gatggaaaaa atcattcgaa ttctgtccat ttctgacaag tggatgacta aaaaagaact
    20461 tgccaaacga attggtagtt cagaatctac atttgtaagg tatatcgaag agatcaaaat
    20521 ccgctgggga acggatgtaa cgattcaatc ttcacaaaaa ttggggtatc gtcttgaaca
    20581 tttgaatgta ccagcttatt taaatgttct gatggaaatg tcgcaaagtt ctacaaacag
    20641 tcgtttatta aatgagatta ttgtcaatcc gggtaaaacg attgagtatt attgtgaaaa
    20701 aatttccatc agccggtctt cttttacacg taagttgaaa caatgcaatc aaattttaga
    20761 aagctattta ttaaaagtga tcgttgacca aggttttcag ttaactagcc ttaaaagtga
    20821 gctccagttg cgtatctttg ttaccttttt ctttttaagt tactacggaa gacgcacgtt
    20881 gccatttcca atcgaaaaaa agaagatcaa agaaattatg gtcaagaata attgtcagat
    20941 gaatttgttt caggaagaaa gcccatatga gcaatctttc tttattatgt attttgttgt
    21001 gcatctcatg agagaatccc aaggaactcc atttgaatgg aaagctggag actcttatgt
    21061 acagttgata aatatcgata aaaaagactt cttaatcttg aaaaatctct taggaaaatt
    21121 gaagtacagc agctatataa aagtagtgaa ctattttgtc aatacgattt tttcagaatt
    21181 ttcggagaaa gaaaaaaatg aaatcagtga gcagatacga aaaaatatgt cctactgttc
    21241 gttttcatcc gctgattgca aagaaaaaaa cgaagaatat gttgttcaat tattaacgca
    21301 aatttatttt ttctcccgta ttttcccata cgatacgact catttgacga tccgtgcaac
    21361 ttactttgca cagcagatgc aacaccgcca gatacgtcta tatgctggat ttcgtgcaga
    21421 acttcaattt tattccactc tactgaatca gaatctgatt tattatttat ctagctatat
    21481 cttttggatg cttatcggta atcctgaaat tcaccattat acttctgata aaaaaatact
    21541 gattatcagc gacttaagtc ttcgacatag tcaatatatt gaagaatata tcagtgatat
    21601 tcttgctgtg cataaaattc actctgagac aactgctatt actgaagatc agctgtcgaa
    21661 atacaatctt ctcgagtatg atctgatcgt tacgaatcaa cccattttga atgcccatgt
    21721 tcctcatata ttgattgatg atagtgtgtc attcgcaaat gaagaagaac tcatccgctt
    21781 attcgagtta tgaataatca aaaaacagct atgtataaac caccctgata aaaatttcag
    21841 gacaaataca catagctgtt tctttttatt gtattccttc agcaatccaa cgagatttat
    21901 agcgaaagtc ttttaacaac tcttcttttg tccaattatt tgcaatgaga tccgtcaaag
    21961 tgttcattac gagggtcatg gaaaagtata ggaaactaac tgcttcttcc gacgattgaa
    22021 tggagaaatg attgattctt aataattcca gccatttttc gttcattgga gaatcagccg
    22081 atagttctct acgtttggtt gtctgctgat catttcgctg ggttaacaag tataaccttt
    22141 gccaatagat actttcgtga tctaagtcgc agcaccactc taaatatttt tcgatcccca
    22201 aaaagaaatg ttgtttgttt tcgctaatga attttaagat atcttgatgg actatgtgag
    22261 aactgctttt gatcgtatac aaataagcat cttccaaatc ttgaaaatat ttataaaaag
    22321 caccgcgcga catccccatc ttgtcaacga tttctgagac tttgacttgg ctgatgtgct
    22381 gtgagcaaaa tatctccagt aataggtcat cgattctctg tttctttgcg ttcgataaat
    22441 tgaaaaaagt ttcttttggc atccacatct ctcctttatc tctgattata cgtggatagc
    22501 ccttcattgt catgaaggat tcattccttc tttttctctt cttctgtcaa gtacccatct
    22561 tccattcgat aaacgcgatc actccattga atcatacgga catcatgagt aaccataata
    22621 gtcgcttttt gtttctcatg agcttcttta actagtaatt tgacgacttc atatgcatga
    22681 tctgtatcca aactagctgt tggttcgtct gctaagatca agcttggctc attatataaa
    22741 gcgcgagcaa ttgccactct ctgtctttct ccaccagaaa ggtctttagg ataactattt
    22801 ttaagtgact ggatatctaa agattgcagc aaggaatcga tttttgttga atcttctttt
    22861 tttgaagtaa cttggtcaac tagttcaaat tgttccttta ccgttaaaaa aggaatcaaa
    22921 ttagagcttt ggagaataaa tcctatttct ttaaagcgta aatctgctcg ttttttttct
    22981 ggaagctcag ttagtgagtg accgttgatc actatttctc cggaagtcgg tgtttgcaat
    23041 cctcctgaaa tggtaaggaa agtactttta cctgaaccag aaggaccaat gatgctgacg
    23101 aattctcctt cctttacata aaaatcaatt gctttcaaag ctgagacctt tgtatgacca
    23161 gaaccaaatg ttttggtaac ttttttcatc gttaatattt ttttcatttt tattaacctc
    23221 ctattgctgt aattgggtct actttggtta tcgtacgtat cgaaaacaat ccgcctagca
    23281 ttgcgacaat gatcaaaatc ccactatata gcaaccattg tgaccaaaaa acagcaaaag
    23341 gcatcgcgct tggtaaaatc agactagtca aataagcaaa caaaagagca agcagaacgc
    23401 ctaccacccc aacaataaag gactgtgcta ctaaagattt agcgatgaag aaatttttga
    23461 tcccttgtgc tttcattact ccaaaaatag cagtcttctg aagtgtcatc acgtacatga
    23521 aaataccgac cacggcagca accactaaga acaaaaagta tatcatcgca tttaaggtca
    23581 tattttgggc agaatagcca ggaatacttt caatgaatgt cccaatagtt aataactgta
    23641 gacccttcga tgctttttct ttcgaaattt tagctgaatc ctttattacg atcccattga
    23701 tcggctgttc ttcttcagaa gcaaacggct gttgtccata cttcaaagca gtccacgtat
    23761 ctagggacgc atagatgacg ggagaaactg tgtaataagt ttcaggaaag ataccgacaa
    23821 tcgtcaaagg atcgtcgtaa ctgccaattt tgatcgtatc tccaatttta tagcctgaat
    23881 cagccagatt ttgagagatg atgatttcat tctttgtttt aaattcatgc cctttcgtga
    23941 gttttggtaa taaaaatgct tctttcgttg tgccgaaaac tgtaacattt tctttgtttt
    24001 ttcctttgat tgctccgctg tacaatccga ttggtgcttt ctctcctcct tcaatgtatt
    24061 tcagatctcc tcttgttaat tgtgaagctg caaatacttg atttgcatcc tccgacaaaa
    24121 caatctcttg tgcgtcccaa tcatcgattg cttttttaaa ctcttctgaa agtccattcg
    24181 ctagtcctga caacatgaat acgacatacg caatcaagaa cataataccg acgatcaagc
    24241 catatcgtaa tttagaatag cgaatttctt tgatagctag aaacatttgt ttttcctccc
    24301 tatgatagat tgatagtgac aaaatgtcac ttgttgaata gtgtaactct aaagtgacaa
    24361 tttgtcactt gtgttgtttt tttcttatca ataaattgtc taagacatct ttcgataaaa
    24421 ccttaacatg agtcataaaa aatttattta agccttattt atgctttcca tgataaacta
    24481 aagtgaccaa atcaatgagg tgggaaaatg attaaactat tagtagtaga agacgataaa
    24541 gtattatcca ataatataaa agaaatactc gctgcaatcg gcgagataac acaagtttat
    24601 gatggtagtg aaggactgtt cgagttggaa agtggagttt atgatcttgc aatcttggat
    24661 ttgatgatgc cggaaatgaa tggatatgaa gtgttagcaa aaatacggaa agaaaaaata
    24721 cagactccag tattgatttt gactgcaaaa gatagtttgg aagataagat tgaaggattt
    24781 gaacgaggtg cagatgatta tctaacaaaa cctttctatc gagaagaact gatcatgcgc
    24841 gtgaaagcat tattgaaacg ctcgctaggt ctctttgatg aaaatgttct gaagtataag
    24901 gatatcagtt gtgatttaaa aagcaatgaa gtcttgtata aagaacaagt tttgcccata
    24961 caaggaaaag agtttgaatt gctcgtttat tttttacaaa ataagggaat cattttgaca
    25021 aaagagcaga tatttgaccg gatctgggga tttgattctg atacgacgat tacagttatt
    25081 gaagtttata tgagcaactt acgaaaacat ctgcgaagta ctggattgga taaagaaatc
    25141 aaaaccttac gtaatgtcgg ttatatactg caaagggtgt gatgcaatga atggagatat
    25201 tacacgaaag caacgtagtc gcttttttgc gacaaatgta gcagcatttg cttttatctt
    25261 ttttcttttg ggattcatta ctttacagat attaaaccaa tctgcataca gagaaacaga
    25321 tctgtcatta gagaaaataa attttgattc tcgaacagta caattagaga tacaaagata
    25381 tcagcaaggc gatccctttt taaacccgac tcaaacggaa caaaacagaa caaacatgga
    25441 acagccatta atggaaccat caaatgaccg ttttaacact caagtgatct tgtggtctaa
    25501 aaatggtgag atattgaata aagcagctat tggtgggcgt ttcaaccaaa tcaaagaatt
    25561 aaaaatggat acgaaaaatc tgaataccat ccaaaatatt gaattaaatg aagacagtgg
    25621 ctcatctgcc ctctctttcc gttcgattac gaaaaaagcg gagacgaatc aagatggcgt
    25681 tgcctacatc caaattttag aaaatacaaa tcaaatcaag aattcattag cgacttttcg
    25741 cacgattatg attttgtgta tgattgtttt ttggattctc tctattggta tcagttatta
    25801 cttgtctagt ctaagcatgc gccctattat tctttcttgg agaagacaaa aagaatttgt
    25861 tgagaatgct tctcatgaat tgcgcacacc gttaacgatt attcaaaata gtttggaaca
    25921 tctttttacc aagcctaatc atactattat tgaagaatcc gaaagcatcg ctcaagcatt
    25981 gtcagagacg aggcgcctca ctggattgac ttcggatttg ctgacaatcg ctcggaatga
    26041 ttctgatcag cagctgcttt caaagcaaat gatcaataca caagaatata tcgaacaact
    26101 tgttaaacca tttcaagaga tggccatcat agatggaaaa gagtttattc tccataacga
    26161 tgcaacatta gaagtaccaa ttgatgaaaa aaaaatccat caagttttgg ttattttgct
    26221 ggataatgca ttaaaatata cgaatccaga agataagatc attttggatt catctgttaa
    26281 ccataaagaa tggctgattc acgtaaagaa tactggccct tctatcagtg aagaagatca
    26341 agcaaggatt tttgatcgat tttatcggga agatcaatct cgggcgaaag agactggcgg
    26401 atacgggctt ggcttggcaa ttgcaaaaca ggtaatcgaa cagcatcatg gacagatttc
    26461 tgtatccaat tatcttccac aaggagtcga ttttaaagtc caattgccgt tgaagcctaa
    26521 aaaataatgc ttatccctaa aaaagggctg tgacaaaaat cttgtcacag cccttttttg
    26581 ttgcgaataa acggtgttcc agaagtagct tcttcggaaa taagccgaaa tttctttaag
    26641 ctgaccactt ctgtcacaac ctctttagct tacgcttacg attttttatt gcggtcttca
    26701 atgtgtacat caccgcttgt gtcaatatcc aattcttctc ggctaacatc ttctgtcact
    26761 ttttcaacat cttcatgttc ttctttatga atcccaactt cttcacgaat aactgtatgt
    26821 ttgcttacat ctacttgctc ttctttgatt gggatagtaa tcgtgtcatc ttccaatttt
    26881 tcgtctgttc cctgtgaaga ttgatctgtt actggtttgc gttcgatgac gatttcttca
    26941 cgtttgaccg gtacttctac cgtttcagta tcgttgacca catgtttgtg gatgtcgact
    27001 tctccagttg tcacatcatg tgtatttaca tctaattttt cttcttttag ttgaattgta
    27061 tcatcatcta gatttggttt gcgatcgatg tcttcagtct tgcttgtacc cattgtatca
    27121 gtctcgccag gtacgtccat cggatcagtt cctggtgtca tattcaatgg atccgttgta
    27181 ttttgaaagc ctgtcgtgcc acctacgtcc attggatctg ttccagtgcc agtttctaat
    27241 ccagtcccca ttgtgcttgc tgggctaaca gtatcttgtg tatccattgt atcttctgtt
    27301 gtttctggct gacgatagcc ttttactgtg atgacaaatt ttccatcaga aatatctcct
    27361 ctatattgat ataaaggatc attttctggt gtagccgtct cagaatcata ggtatcaaaa
    27421 gaaaaagtat cttttatttt ttcccataaa gaacggtctt cttcaccatc catccgattt
    27481 tcatctgttt caacatctat accagacaat ccgtcaaatc ctagtctaga tgctgcttca
    27541 tcagtagtat aaataacgat atcatctcgt tcataccctt cgttacgcaa ccgttcaatt
    27601 actgataatg cttcttccct cgtactatag cttccgatga ccgttaaatt tttctcttcc
    27661 atgtaaattc ctcctagcaa atagatttat gattggtata ttgttactta taaatttatt
    27721 ctataggaga cgattgtttt ctacaaatat ttagattgga atttgattaa aa
//
LOCUS       DARBDN010000024        27590 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000024 DARBDN010000000
VERSION     DARBDN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.024"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(409..768)
                     /locus_tag="SCH06_001106"
     CDS             complement(409..768)
                     /locus_tag="SCH06_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEG1077701.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(798..1139)
                     /locus_tag="SCH06_001107"
     CDS             complement(798..1139)
                     /locus_tag="SCH06_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077702.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(1136..1810)
                     /locus_tag="SCH06_001108"
     CDS             complement(1136..1810)
                     /locus_tag="SCH06_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEG1077703.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(2986..4284)
                     /gene="asnS"
                     /locus_tag="SCH06_001109"
     CDS             complement(2986..4284)
                     /gene="asnS"
                     /locus_tag="SCH06_001109"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEG1077704.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(4324..5514)
                     /locus_tag="SCH06_001110"
     CDS             complement(4324..5514)
                     /locus_tag="SCH06_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEG1077705.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(5535..6062)
                     /locus_tag="SCH06_001111"
     CDS             complement(5535..6062)
                     /locus_tag="SCH06_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEG1077706.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(6109..8898)
                     /locus_tag="SCH06_001112"
     CDS             complement(6109..8898)
                     /locus_tag="SCH06_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEG1077707.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNGKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(9045..9245)
                     /locus_tag="SCH06_001113"
     CDS             complement(9045..9245)
                     /locus_tag="SCH06_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEG1077708.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(9698..10018)
                     /locus_tag="SCH06_001114"
     CDS             complement(9698..10018)
                     /locus_tag="SCH06_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077709.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(10521..11639)
                     /locus_tag="SCH06_001115"
     CDS             complement(10521..11639)
                     /locus_tag="SCH06_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077710.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            12110..13417
                     /locus_tag="SCH06_001116"
     CDS             12110..13417
                     /locus_tag="SCH06_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEG1077711.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            13538..14737
                     /locus_tag="SCH06_001117"
     CDS             13538..14737
                     /locus_tag="SCH06_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEG1077712.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(14764..16032)
                     /locus_tag="SCH06_001118"
     CDS             complement(14764..16032)
                     /locus_tag="SCH06_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEG1077713.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(16202..16843)
                     /locus_tag="SCH06_001119"
     CDS             complement(16202..16843)
                     /locus_tag="SCH06_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HEG1077714.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(17252..17755)
                     /locus_tag="SCH06_001120"
     CDS             complement(17252..17755)
                     /locus_tag="SCH06_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEG1077715.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(17878..18642)
                     /locus_tag="SCH06_001121"
     CDS             complement(17878..18642)
                     /locus_tag="SCH06_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEG1077716.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            18750..19025
                     /locus_tag="SCH06_001122"
     CDS             18750..19025
                     /locus_tag="SCH06_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEG1077717.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            19585..20535
                     /gene="yidC"
                     /locus_tag="SCH06_001123"
     CDS             19585..20535
                     /gene="yidC"
                     /locus_tag="SCH06_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEG1077718.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(20581..20982)
                     /locus_tag="SCH06_001124"
     CDS             complement(20581..20982)
                     /locus_tag="SCH06_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEG1077719.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(20996..21805)
                     /locus_tag="SCH06_001125"
     CDS             complement(20996..21805)
                     /locus_tag="SCH06_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1077720.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(21792..22682)
                     /locus_tag="SCH06_001126"
     CDS             complement(21792..22682)
                     /locus_tag="SCH06_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1077721.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(22695..23174)
                     /locus_tag="SCH06_001127"
                     /pseudo
     CDS             complement(22695..23174)
                     /locus_tag="SCH06_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            complement(23350..24291)
                     /locus_tag="SCH06_001128"
     CDS             complement(23350..24291)
                     /locus_tag="SCH06_001128"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HEG1077722.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(24288..25283)
                     /gene="lacD"
                     /locus_tag="SCH06_001129"
     CDS             complement(24288..25283)
                     /gene="lacD"
                     /locus_tag="SCH06_001129"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEG1077723.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(25276..26472)
                     /locus_tag="SCH06_001130"
     CDS             complement(25276..26472)
                     /locus_tag="SCH06_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1077724.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(26490..27218)
                     /locus_tag="SCH06_001131"
     CDS             complement(26490..27218)
                     /locus_tag="SCH06_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1077725.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
BASE COUNT         8009 a         5892 c         4783 g         8906 t
ORIGIN      
        1 atttcttcca tacagatgtt ttggcttatt ctttcttttt ctcttcgatc attgcccctg
       61 ctcttatcca acccgcactt gccttcttga tcttgacagg atagcaacta agtttgaagc
      121 ctgttgctgg caatttgtct aaattcatta atttttcgat aggacaatat cttttttcaa
      181 tccctgcaaa atgtccttcc cagatattcg aagctccact acgctttcaa aaatatagaa
      241 agagttcttt aatgaaaatt atttcaactt tccataaaca gtaatcccat ataaataaaa
      301 gacgtaaaag tcacatggga gaacttatac aggaaaacac atagagtcag gtgaaataca
      361 tgtatcccac ctgactctat gcgttttcta acctttatta ttctcttttt atacaatttc
      421 tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg caaaaggtat
      481 ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag caattggtag
      541 gcctgaaacg atcagccaga tgatattaac gatcaatgac atgccagact ggtgataaat
      601 tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt gcataccgat
      661 tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc taagaccacc
      721 gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg tatttctcct
      781 tctattactg tttttgatta aaactgggca aaaattgatt ttattcttct ttttttagct
      841 tccagcatca agtattctgc aaattttttt tggatttctt ccgtattttc ttttgttact
      901 aatgtgtgtt ggattagttt tcctgatggt cgctgatcca cccgttcttc tgactgttgc
      961 acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac gagcaatagt
     1021 ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc tggatgatca
     1081 gtaatcagct gattgatttg aggtaaatct tcttttactg cccaccgtat ttccatcatt
     1141 tctcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg gcaattgcat
     1201 ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc ccatcttctc
     1261 ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt gaatatgcca tctaaaggaa
     1321 ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta gggtctaagt
     1381 ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc atcaagatga
     1441 tgttgcagat ttccgctgtt tgaagttcat ttagtaattt tcgataaacg gattcaaatt
     1501 gctgcgcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc caggtatcat
     1561 tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct tcttgccagc
     1621 gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat tcaaatttca
     1681 tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct ttacctagat
     1741 cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct gtcaccgata aataatatac
     1801 gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt ccttatatta
     1861 tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga caccagccta
     1921 gtcccttcaa tcaattgaat gaacgctcat caagtgtcta gttttttata ctttttttct
     1981 taacgtgccg gattcccctt gattccttcg ttgtttggtc cagagaaatc gatcacacct
     2041 aagcttccgt caatcagacc actgatgacg ccatcagaac atatatttat aggctcatct
     2101 aagacttcca gtaaatgttc ttttactaat atctcttcta gattgcttgg gatagattgg
     2161 tcataacttt atctggtccg atgatttcaa ggatgaatta aacttacata tggatcattg
     2221 catgctgaaa atacggacct actccatctt cgaatgttac tattagtttg ttttcaggta
     2281 ctagatgctg ctttatttca acagcagaag catcatcaaa tcagatttcc atttgaataa
     2341 ccttctttgt atatgtttga ttgattgcga tttcgttata gaaccttgtg aatcaaatag
     2401 caatttcttt tgctttcttc tcttgtctgc tggaaacttc ctttatcccg tattttaaaa
     2461 aaagaactgc gagagttcgc agttcttttt tttaaataaa cgttgctctc cggccaactc
     2521 ctcggtcaca agtcacaata gtcatcaaac atgaaaaact gttttttgaa attactcctt
     2581 gtgactcgga gctgaacggc aggcgcacaa cctcttgata taaacggtgt tcaatcagct
     2641 gaccctcgat attagctaaa aaaacggtaa aatatgagaa gctatttttc cgttttgttt
     2701 ctctaatact caggtcaagg cactgatttc acaacctctt ccttaaacgg tgttcaaaag
     2761 ccagtttctc ggtattaagc caaatttatg caaaaatgtg gaaagccatt tccacaaaat
     2821 ttttcttaat actcgaaact aaacagcttt ttcacaacct ctccactaaa cggtattcaa
     2881 aagcttacat ctgcggtaat aagtcccgcc aattcaaaaa catgaacagc tgtttttgct
     2941 tggctgttct aattacttga tgcagaacag ctttttcatc acctcttatg gataaattcg
     3001 gttcaacaaa cgtgggaatg gaatagcttc acgtacatgg tcgataccag caatccaagt
     3061 gactgttcgt tcaaggccta gaccaaaacc agagtgcgga acagaaccgt atttacgtag
     3121 atcaagatac catgaatatt ctttttcatc caaaccgtga ttacggattt gttctagcaa
     3181 gaaatcatag tctgttgccc gttcgcttcc gccaataatt tcaccgtaac cttctggtgc
     3241 gatcatatct gcacaaatta ccacgtcttc tcttgttgga tgtggtttca tgtagaatgg
     3301 cttgatggct tttggatagt ttaggataaa gacaggctgt tcgaatgaat tcgcaatgaa
     3361 cgtttcatga ggtgaaccaa agtcttcgcc ccattcgatg tcatcaaatc catttttctt
     3421 cagtaattcg attgcatcat cgtaagtaat acgagggaat ggcaattttg tataagtttt
     3481 taagacttct ttgtctcgtc ctagtacatc taatgcatat tcgcaatgat ctaaaacatt
     3541 ttgtactaag aatgctacat attgttcctg tacttctaaa ctttcttctt gatgagtgaa
     3601 agccatttct ggttcgatca tccagaattc gatcaaatga cgtcgtgttt ttgatttttc
     3661 agcacggaaa gtcggaccga atgaaaagac ttttccgaaa gccatagcag cagcttccat
     3721 gtataattgg ccactttgag ataaataagc tttttgatca aagtaatttg tttcgaatag
     3781 atccgtagtg ccttctggtg cagaaccagt caagatcggc ggatcaattt tgacaaaatg
     3841 atgttgatta aagaattcat acgttgcacg aatgatttca tttctgatct gcataatcgc
     3901 atgttgtctt gaagaacgca gccataaatg acgatgatcc atcaagaagt ctgttccgtg
     3961 ttcttttggt gtgatcggat aatcgtggct ctcgcttacc acttccacat ttgtaattcc
     4021 gatttcataa ccaaattttg aacgactgtc ttcacggatt tctccagtta ctaacacgga
     4081 tgtttcttgg tgtagatttt tagctgtttg gaaaacttct tccgacactt cgctttttac
     4141 aactacacct tggaaaaagg ctgttccgtc tcttaattgt aaaaatgcga tttttccgct
     4201 tgatcgctta tttgcgaccc aagcgccgat tgttactgtt tctcccacat ggtttttcga
     4261 atcgatgatt tgaatttgtt ccacgtatga ctctcctttt atattccttg aatttcttca
     4321 ggattaattt tgacttttac tctcaataaa ttgcttgatt ctgcgtaccg cttcttctaa
     4381 cgtagcgcga tcagtggcat aactcatgcg gacattttct ggtgccccaa agccttcgcc
     4441 agtcacaagc gctacccctg tttcttctaa aagatcttct acccattgtg tgacattttc
     4501 atacttacac atgcgtagcg tttcttttac attaggaaaa agatagaaag ctccttgcgg
     4561 cttttcaaga gaaacacccg gcagttctgc cacaagcgga tataacgtat tcaggcgttc
     4621 ttcaaaggcg ttccgcattt cttctactgt atcttgctca cctttcaatg cttcaacagc
     4681 tgcatattga ctgactgctg tcggattgct agttgattgg gaagcaacag cgatcattcc
     4741 attgatgatc acaggatttc ccaccgcata accaatgcgc cagcctgtca tcgcatatgt
     4801 tttagacacg ccgttgatga tgatggtctg atttttgatt gcttctgaaa tcgttgcaat
     4861 tggagtaaac tcattgccat tataaactaa acggccataa atatcatcag caactatcaa
     4921 aatatcattt tttactgccc attcaccgat tgcctgcagt tcattcttgc tataaatcat
     4981 tccagtcgga ttcgatggag aattgatgat tacggctttt gttttttctg aacgtgcttg
     5041 ttctagctgt tcaacagtaa ctttccagct attggattct tcccctttca caaagacagg
     5101 aagtccttct gccagtttta cttgctcacc gtaactgacc cagtaaggca caggaatgat
     5161 gacttcatct tgcgggtcaa ggatcgtttg gaaaagggta tacaaagcaa atttcgctcc
     5221 gtctgttacg actgtttgtg aaggttcata gacaagtcca tagtttttct tcagataatc
     5281 aacgattgcc tgtcgaagct ctgggattcc tgctgttggt gtataatagc tagctttccc
     5341 attgcggatt gcttcgattg ctgcttcttg gatgttttct ggtgtcgcaa aatccggttc
     5401 tcccacagtc aaactcagca catctctgcc ttttgctttt aatgccttgg cctttgccgc
     5461 agctgccaaa gtgacagacg gttctaatcg ttttgttctt tttgataact ccatcccatt
     5521 cattccttta ccttttaaat tcccttgatt gtcttgactt catctccaga ttcaaagcca
     5581 atcaggtaat aattcagttt cccatttgtt tcttttccta ctacttccca cacaggctga
     5641 tcatcataca tccctaaagc agctttttcg atttggattt caggatgggc cgcagcaatt
     5701 gtctgttttg cttcgttttc agtcagtccc tttgtttgat ccaatacttt tactttttca
     5761 ccagatttag gaatgataac ggcgatttct tttcctttat catttgtacc tgtcagtgaa
     5821 aagtatgtct tctttcgagt aaaccaataa aaatgatcgg tttcctcaag atttgcatat
     5881 ttctttgcga tttctactgc ttctttcttc gcctgcaccg ccggacgact ggaacgcaag
     5941 taaaaaatcg agctgatcac gatgaccgct aataaaaata cgatcaagcc aagtaacacg
     6001 cgattaatcg ttttttcctt tgtctgtttt ttcttcaagg gtcgtcgctc ctttatcttc
     6061 attccttttc attatagcag attttaatta tgaaaaaaga cagctcctct aacttccttc
     6121 ttcatttttc tttaagaatt catggatatc ctgatagatt tcctccatag ctagctcttt
     6181 gatcggtact tttttcggta atgcatggat gatccgtgcg ccatattttg cagtgactag
     6241 tcttcgatcc aaaataagca atacgccacg atctgtctcc gtccttatca agcgacctaa
     6301 tgcttggcgt aacttcaaag ctgctttagg tacggattcc tggtaaaaag gattgatccc
     6361 ctctgattct aaataagcgt tcctagcttt gaccatcggg cgaagcggat tatcgaaggg
     6421 taaacgtgtg actacaacga tctgcaaagc atctccaggc aaatctacac cttcccaaaa
     6481 gctgtcagcg ccaaacaata cgcttttttc tgacaaaatg aagcgtttca aaagcttctc
     6541 ccggcttcca ccaaaccctt gagctagtat ttctcgtcct ttttctagca tagacagatg
     6601 cattttctga tagaccttct gcaaaacatc atgagaagtg aataacacaa gtattggccg
     6661 atcttcttgt tcgatcagac ctgtaagtgc tgtctctaaa taatcgatat atgcttgatt
     6721 gctgacttga tggacggcag gtgcctcttt tggcacatag atccttgcct gtttctcata
     6781 atcataagga gaggcaatca ctttaagagg tgctgcttca atgccaagcc tcttagagag
     6841 atagtgtcga ttagggccga tcttcagcgt tcctccaata taaagaatac gatcatatcg
     6901 aggataccaa acagtcgacg gcaacatagc cgcttgaaaa tcatggagat gaaaaatcat
     6961 ctgctgcgct gtgttcccag gaacgaacca atggatcaaa tgatctcgcc agtcttccag
     7021 ccattgatcc atcagcaagt attgcttgtc taattgatca aataggctat ataaacttgc
     7081 taaatcgatc cgcatctggt ttgtccagct ttcttggata atctcaaaag tcagacgcat
     7141 ttgtgactgt agctgctgga tctcctgata aaaaagctgc aggtgatcaa tggctgtccc
     7201 agattccagt ggcagctgat ccaacatctc ttttgtcatc atgacttctt ctggatactg
     7261 tccgttaggt tgcttgccgc tcactaaact cattaatcct tctgccatac aaatctgtgc
     7321 ttcgcatagc gcagaaagtt cttctcgata aatcgataac cagcgtaagg cttcatgttc
     7381 tttcggtaaa tagctttgta ttcggtcaaa cagctgattt ggttcttcta attgctggat
     7441 ttgtttatgg aaatagttaa tacttaatcg tttgccattt actttttcag cgatttccgg
     7501 caaatgatgt acttcatcga tcaacaaaaa tggactagct ggaagcaatg gttcttttcg
     7561 ctgtgtttct tgtactaaaa acgcatgatt gacaatcaaa aaattacttt gcctgatttt
     7621 cttttgcaag aaacgaacaa agtcttgttc gtaaaatgac tgatttcttg ctaaaaatcc
     7681 aatacctctg tgcgcgatat ctgcaaagaa tgaatggttc aaatttgtta aatgtaattc
     7741 atccaaatca ccagtcttcg tttgcgtcag ccaaactaag accgccattt gatacaaagc
     7801 atattgtttt tgttctggcg gttccacaag tgtgccttta aaacgctgca aatcaatata
     7861 gtggcgatag cttttgataa ttacaggttg tatgggctga tctagcaatt gattcagcaa
     7921 tggaatgtct ttttctatga tctgctgctg caaaactagc gaaacggtac tgatgacagc
     7981 gggtttttca ggtgtagcca aataactcaa tggcagcaga taaccgattg ttttacccat
     8041 tcctgtagct gcttcgatca tcaaatcttt tgattcatct tttgtgaaat ggtcgtagac
     8101 cgcattcatc agtctgttct gttcttttcg atacatcagt gttttaccaa acattttttc
     8161 ttttgcttgt ttttttcttg gatatgtccg ctcgccataa tggacggatg tgaatagttc
     8221 cacttctttt ttctgcaaag ctagcccatc gacgatttct aatgagggat caagtggctc
     8281 tggtttttct ttcatttctt caatcacatg ataaatgaaa cgactcgtat ccatacctgt
     8341 gtgtctactt aatcgcgcaa tctgctctaa cgtgatgatt ggcaattttc tcatccgttc
     8401 ttcgatcagc aaaagaagtt gacctgtcac ttcggcatca ctatctgcct gatgaggatt
     8461 ctcatgaata aatccaaggc tttctgacaa atcagctaag cgaaagcttg gttccgtcgg
     8521 caagaaaatt tgtgcaagtt ctactgtatc gatgcctggt atcttcaaac taggaagtcc
     8581 gcatcgcatg agttcatggt tcaaaaaatt ataatcaaaa taaatattat gcgcgacaaa
     8641 tatggtgtct gccaaaagat tgtaaatcgt ttgggcgaca tcttcgaaat aaggcgcttt
     8701 ttggacgcgt tgattcgtga tccctgttaa atgctggatt tgttttgaaa tcttccgccc
     8761 tggatgaata tcgatcgaaa aacgtgaagt gatccgacct gattcaatca tgacgcagcc
     8821 aaattggatg atccgatctt cttttggatt cgtcccagtc gtttcgatat caacgactgc
     8881 ataagttctt ggtttcaaaa tatcttcctc ttctcctgcc tctaatgttc ttttgaaatt
     8941 atactacaaa gtgcagaaaa atactctcat cgctttttaa agaaaataga caaaaacgcc
     9001 cagacacgca aatgtctggg cgtttatttt ttagtatagg ttaattaagc tttagtaacg
     9061 tttgttgctt gaggtccgcg ttggccttct tcaacatcga aagttactgc ttggccttct
     9121 tctaaagttt tgaatccgtc gccttggata gctgagaaat gaacgaatac atcgtttccg
     9181 ttttctgcag tgatgaatcc aaatcctttt tctgagttaa accattttac tgtacctgtt
     9241 tccataataa aaatcctcct tgtgtatcaa cacatatttt gcaattactt gaatggtgta
     9301 tatctggaag atgtttattt gaaacaagct accacagatt accgaacaaa aactactcct
     9361 atagtatatc ataccgttta caaaaaagct agagtttttc gacttttttt attaaaaaaa
     9421 gttttctcag cgattacata aagtgaaaaa ccgaactttt ttttaaaata aacgacatat
     9481 tgttcagttg gtgttttttt gctctgatgt tcttttttaa actaaaaaaa ttattctttc
     9541 tgactactta tcggttctgt ttcaacggtc gaggctgggg aagattcttt agtaggtctg
     9601 atgttctcat ggtatttctg atagcctatg acagttacca gaagaacaag gcaaaccaat
     9661 acgaccaacg agattagttt ttcttttttg ctcatatcta tacctcataa ataacaggat
     9721 gatgtccatc atatttctga gtatgagtaa aagcaaaagc tgcagctgta gaatgtaaga
     9781 aatgccagca actttcataa tcacaggtcg gacagtacca aaagtaacca aatcttggct
     9841 gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag atctggtgtc tgtacataaa
     9901 catttttgta cagacgtgtg cctgtaatag gaaaccgctg tgtttcttca gcaaaaactg
     9961 gctgacttgt taaacttagg gatagagaca gcaaacacca taacagtctt tttttcataa
    10021 agacctcctt atcgataagt ttttcccaat taaaatcata tctcaagaac gcccgttatt
    10081 cacattttgt tcataaatga tgttttttgt atcataatcg tcaaaaagag gtcgtgacca
    10141 cgtcacaacc tcttttttaa acggtgttcc agaagtagct tcttcggaaa taagccgaaa
    10201 tttcacaaaa atttgagaaa taatttttgt caatctcttc ttatttcttg aagctgacca
    10261 cttctgtcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    10321 caccaaacaa aaaatatgaa gagctatttt tgcttgctgt tcttattact tgatgcagaa
    10381 cagctttttc acaacctctc atacacggtg tttaatcagc tgaccttcgg tattagctca
    10441 aaaaacggca aaatatgtga aactattttt ccgtttgttt ctctaatact caggtcaaaa
    10501 cactgatttc acaacctctt ttaataacga agaatcgctg tcagactctt ttcatctggc
    10561 gcatcttttt gatccaaaat aaacactttt ccgccattaa tgatcacatc atctgctaat
    10621 gcattcaaca cttgacgccg atcatattct gtttcaggat cttcaccgaa accatcagct
    10681 aagtttgacg tagcgataaa taaatgtgac acttttcctt ctttcgcagc tggaacgata
    10741 tcaactaact gatcgatgaa tttcttatct aagagtttat tgtattcttt tgattcttga
    10801 gctgcgagtt cacttgacag cttcttcgcc ccttcttcga tatctctaaa ggatagctgc
    10861 gcaggagaag cagaaatcgc aacgtctgca caataatagg gatttttagc aatttttttg
    10921 aacatcgtct gattttctgg tagagcaaat aaataaatcg gccattgttc tggattttcg
    10981 aaagaatcct tcaagtacgt atcaactgct tggtaatagt tgacccaatc gatctctact
    11041 tcttcatctt ttggatttac gccatggaaa gttactccat ctcgggctcc gcctcctcca
    11101 ttagaagaga agttcaaacc gccacctgtc agttcagatc ccaatgcagt aacgacatca
    11161 accggtgccc cttctggtag agatacttct tttacttgtt tgttgctgac ttcatacaat
    11221 ttcatggagt cgcggttcaa tcccaataaa taataagaat agttgaactg cccatttttg
    11281 ataatagcca gtaaataagg aagatcactt acatagtatt gatcgtctac cgggatactc
    11341 aaacgatgga tataggtttg gtcagcagtt ataatgaccg ctacactcgt agttgcacta
    11401 cgccaaaacg aaggatctcc taacaaattt tcaatttttt cttggaacgg ggaccagtca
    11461 tgttcggaat attttttctc aaaacgtttc tttgcttctt tcgcaaaatt tttgaatttg
    11521 atctgatctt tttccacatc ttgatgggcg acatgcgtat tcagcatgat cgtgacgaat
    11581 ggtcctttag cgccttctga agtcaattgt gacaataatt ctttatcctt ttttgccata
    11641 aacgtacccc tcctaaaaaa atcattcctt tgtttctatc taaagtctac cacaacacta
    11701 tttttccata caataaaacg tatctaaaaa aataaaacgg tttctacggt tttaaattta
    11761 gctatttttt taagttatct tcataatttc ctcaattatt tagccccagt cttcaactat
    11821 tcttcatgaa atgctgataa actaagaaaa agaataaaag aggtggatct tatgcatttg
    11881 attatgattt tcagtttatt aagtattatc agtttatttg ctttcagcgc ttcccgctta
    11941 ttagatgcgg aaacacagcc tattcctgta aaagtacgta aaaacgaccg ctaaccttcc
    12001 ataacgtgcg ttcttatcct aaagtttttt cagaaacatt gaaactctct cccctctctg
    12061 ataaaatttt aatttgtagc gaaacaaatt aattacaagg agatcggata tgtccataaa
    12121 aaaaacacgt ctagtcctat tattggctag tctcattctt tgccttgctt cttttctacc
    12181 agctgttgct gtgcaagctg aagatacttt caaagtaaat gcaaaagcag cctttgctgt
    12241 agatgcgcaa agcggtaaga ttctttatga tcaagatgga gaaaaaacca tggggatcgc
    12301 ttcaatcaca aaaatcatcg gtctttacat cgtccttgat caagtaaaag aagggaaact
    12361 atcatgggat gataaagttt caatttcaga ttatgcagaa aatttgagtg tcaccccaga
    12421 tttatcaaat gttcctttgc ataaagaaaa cacctacacc gttaaagaat tattcgactc
    12481 tgcaatcatc cagtcagcca acgcttcaat ggttgccttg gcagaaaaaa tctctggcag
    12541 cgaagcaaaa ttcactgaac gaatgaaaga acaattgaaa gattggggta tcaaagatgc
    12601 aacgatcgtt aatgcatcag gactgaataa ctcttatctt ggcgaaaacc gaccagaagg
    12661 tactggagaa aacgacgaaa atcaaatgtc tgctcaagat gtggctatcg ttgcccgtca
    12721 tttgatcttg gattttccag aaatactgga tgtatctagc actacgacac aaatgtttgg
    12781 cgaaaacacg caatcaccag tagaaatggt caactggaac tggatgctcc caggattcgt
    12841 gaattataaa gaaggcgtgg acggattaaa aactggtacg actgaacttg caggagcctg
    12901 tttcgtcggt acgatcacta aaaacgatca acgaatcatc actgtcgtat tgaatgcaga
    12961 cggccatgcg gaaaacccaa gtgcccgttt caatgaaaca gctcgcttaa tggattattg
    13021 ctacgacaat tggtcagaaa aagagcttgg aaaagccaat gcaagtatcc ctagtctaaa
    13081 aaccattgat gtaaaagacg gaaaagaatc aacagtgccc gttgtgctta aaagtcctgt
    13141 aaaagtatgg gtacggaacg atatggatac tggaaaatta acaatcacac caactcttga
    13201 caaaaaacaa gtcactgaca atgagatcca agcacctatg gataaaggaa caaaaatcgg
    13261 taccgcaacg atcaccttgg cagaagataa attaggttat cttgaagaca acaacgcgcc
    13321 atccacagaa atcatcacgg ataaaaccgt agaaaaagca aatattttcg ttattggctg
    13381 gcgacgcgtc gcagaatttt tcggtaactt gttttaattg aacaaaaaga aaaaagcatc
    13441 tttccatgtg gaagatgttt ttttgctttt tctagtttaa ataacagctt ttttcatcta
    13501 ttttcgttat actgtataag aaaaaggagt tgaatttatg aatctaacca gagatctgat
    13561 ttttttggtt ctctatctta ttggggtatt ctccatcgtt tattggcgaa aacagaaaaa
    13621 ggatccttcc ttgttctttt acagcagtac atggacgttt gcggtaatct tgacttattt
    13681 tgtcgtgttg gaaatttttt attcgacctt ttattttttg attcccttag tgtttttcag
    13741 tatctttgcc ttttcctatt tttcagaaaa gcgaaggctg ttgaatggtc ttttattcaa
    13801 tattttcctc attagttttg gtatctactt gtttgtcttg ctatacgaaa cacaaaatat
    13861 ttttcttggc ggactgattg ccttgatcac gatcccgtta ctgcttgtct ttctattcgg
    13921 catttatgga ttgatcgttt ttcttttttg gaacggtgtc acagttttac gtagagagtc
    13981 gcattcatta gctaatcttt taacgttgat actagccatt tttcttacat tgtttcttgt
    14041 ttttgacttt ttcttgttaa aatatttacc acaatggata aatgctttgt ttttctgcat
    14101 cccattgatc ttgatctatc tatttatcgt attctacaac tttttgactg tctcattctt
    14161 gtatcagttc aaccgccctc gatacaacca agacttcatc gttgtgttag gcgccgggtt
    14221 gatcaatgga gaaacagttt ctcctcttct tgccaagcga atcaataagg cgattgcttt
    14281 ttattgggca caaagccgtg cgacattaaa tccgcctatc ctattaatgt cgggtggaca
    14341 gggagcagac gaaaaagtac cagaagcaat ggcgatgaaa caatatgcca tggaacaagg
    14401 aattcctgaa agagatattc ttgtcgaaac caattcgaca accactttgg agaatatgcg
    14461 ctattcaaag gaaatcatgg atcagcaaat gaaaggtccc tatcgcgcga tcttcagttc
    14521 caacaattac cacattttca gagctggtct ctatgcacga caagcgaaac tgaaggcaaa
    14581 tggcattggg gcaaaaacag ctttctatta cttgcctaac gcgtttttaa gagaatacat
    14641 cgccatcttg atgatgaaca aaaaaagaca tatgatcatt tgcggattgc ttttcgcagg
    14701 ttccgcattc ttatcactga tcactttact tttctaaaaa aacaaggtgt gacaaaacat
    14761 atgtcacacc ttgttttttt cttttattct cttgacgatt ggcaagaata gtattccttt
    14821 tttgacggct acttgctgtg cagaataaat accgctgttt cctgaacaca taaagctgat
    14881 caagcagatc ataaagaagt aagcagcagc ttgtgaacca aataattcga ttcccatcac
    14941 aaaacaggca atcggtgtat ttgtcgcacc agaaaatacc ccgataaaac ctaatccagc
    15001 aagaaaagga acagaaacat ggagcaaagg cgctagtact gcgccaagcg ttgcaccaat
    15061 ctcaaatagt ggtgtcactt ctcccccttg gtaccccgca cctaaagaca agaccgtgaa
    15121 gaataatttc ccaataaaat cataagcatg tgcctgtcca ttaaatgatt cctgcagtaa
    15181 cggaagactc aacccaaggt aacgttgtgt ttgcaaaatc aacgctgcgg ctacaactac
    15241 tgctccacct atcgtatttc gccaaacagg atgaggaatc cattgcgcat accgcgcttt
    15301 taaaaagacg atcgaacggc tgaataccca accaatcaaa ccaaaagcaa tcccagcaac
    15361 aaaaactttg aagaacagca acatactcca ttcaggaatc acacccattt ggtaatgtag
    15421 atgagaaaca ccatagcttt ctgtcatgaa atttgcaaaa agcgcagcaa agaagctagg
    15481 aaatattgct tctgttcgga ctttaccgat tgccaacact tctaatccaa ataatgttcc
    15541 agctaaaggt gtgccaaata cagaactaaa acccgcactg attccactga taaccaaaat
    15601 ctcccgttct gctttatcca atcggaataa atgcgctata ttatcagcta atgctccccc
    15661 catttgaact gctgttcctt cacgaccaac agatccccca aataaatggg tagtgatggt
    15721 cccaaacaag gtcaatggaa tgagccgcaa agggatcttc tcttctcctc cattcccttg
    15781 atcgatcact aagttattcc cacgactaga aagaccgcca tgatacgcat aaagataagc
    15841 aaaaagcgcg ccgctgactg gcaatagata aagtagccaa ggatgtgcta gtcggatatc
    15901 tgtcacgaac gtcaggctat ttaagaaaaa agcagacaag ctccccatga atactccgag
    15961 aatcgctgtg accaccagcc acttcaacat gtacatcaaa atacgcactg gactcggtaa
    16021 ttgtttttcc ataaaaaatt cctcctcaaa taaaaaaacg cctactaaag aaaggggctg
    16081 gccccagact ttagtaggcg tcattagcta tcttacgtta gcatttaaag gcgaacacca
    16141 tcacctattc acttccatta aaagatagca tatttttctg taaaaaacaa taaaattatc
    16201 gttatttctt tacacgttca gcaaattcat agaaaggagc caatttcgtt aactgttgat
    16261 tacattgatc actatcatga caaatataat tccccttttt cgtatacgtg ccatcagaac
    16321 cggctttcgt tgtagaaaga aagagcgaga cattcgatgt tttctgacag atcgcacaga
    16381 ttcccttatt aatcgttggt gataaagtac cgctgatccc ttttaatttt ccatcttcgt
    16441 aataaaccat gaattttttt tgcgtccctg gatcattcca accgatgtac gtatgtgctt
    16501 gcaagtcgat ttcattccaa gcgggttgtt tgagtttttt cacttttcgg aataatttct
    16561 cgatttgtgg tttgctcggc tgcataaacg gctggacgat ttgcttcagc tcctccaatg
    16621 ctcgttctgc ttgcgttttt gtcagtttta catctaaaac tgtcgttaaa aacgtatcga
    16681 tttctgatgg ttcgtaacct aatacatcgc gaatcttttc agctgctaga gcctgaaccg
    16741 tttgtaccgt ttttgagtca ttgacagatg agtacgcatt taataactgc tctacttctc
    16801 tttttataaa aaaatattga tatggtttca ttgtttgttc catgatttta aagtcctttc
    16861 ttctaaccaa agtgcatact ttgtagaaaa aagtgatctt ctgcaaagta tgtgttacct
    16921 gaagatcccg gactctttta aataagatac gttttgcatc ttatcatcac cccctttaat
    16981 gttcattctt ctatgtacat gattcattcg ataaataaaa gtaaaccgta tcttgagcag
    17041 atagtcaact gcaaacagaa aaaggactgt gacaaaagtc gtgtcaaagt ccctttctac
    17101 aaacaaacgg tgttccagaa gtagcttctt caaaaaataa gccggaattt cacaaaaatt
    17161 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgacccact tctgtcacaa
    17221 cctcaatatg gtctattatt ggttttacct gttaaatcga ggattctttt ccgaagtaac
    17281 gttgccatct cttacgcata cttgctgaca taggctgagc ggcttctttg actgcgcagt
    17341 atttgtctac gaatgttacg atatatcctt ctttgtactt aggcggtgca atcgttgcgc
    17401 cccacatgtg cttcaaaatg atatctcgct caagatccga caaatcggtg atcttttctg
    17461 cattctttac agcgattctt ggatggatat acgcatgtgt gccttcatca aatttcgtcg
    17521 tacgccaatc atagtagaac agatcatgca aaagtccagc acgcgctgtt gctttagcat
    17581 tgccacccca tttttttgcg agcagataac tatagtaaga aacactgatg gaatgctcca
    17641 aacgagtgga atgaacatgc tgtgtgtaat tcgctaattt tttcactgct tctgtttcta
    17701 aaagatcttc tacataagac atatattctt cgtcttcacg ccatttttct gtcataatta
    17761 tcgatctgcc acctttttga atttcatttt cttctgaaat tgatctaagt ataccaccag
    17821 tgttcggatt attctagtcg ccttggataa aatagccaaa gcttaatagt tccttaatca
    17881 taaagaaaaa tgataaagaa caatccctgc cgcaacccca acattcaacg attccgcatt
    17941 tcctttcatc gggatatata cgttctgatc agtcaaagac aagatttcct gacttacccc
    18001 ctgaccttcg ttccccatga ttattgcgaa gttatctgat ttttctactt tgtctaaggc
    18061 gtgtgcttct tcatttaatt ctgtgccata cactgtaaac cctttgtctt tcattaaagg
    18121 aatcacttct gtcaaatctt tttgcaacac aggcaaatga taattgcttc cctgcatgct
    18181 gcgcagcacc tttgtactat aaatatctgc cgttcctttg cctaataaaa caccagccat
    18241 atcaaatgca tctgccgtac ggatcatcgt ccctacattt ccaggatctt gtacattatc
    18301 taataacagc catcctcctg aaaaatctgg cgtgccttca gccgttaacg ccatcactgc
    18361 taagattcct tgtggtgtag gtagatccga tacagcatcc atgacctcat ccgaaactag
    18421 aaaagtagaa atctctttgt ttgcggccag ccagtctccc cattctttca tgcctcgctg
    18481 tgtcacaaaa agttctttta tttctgcatc agacgacgca gcttcttcaa tcagatggaa
    18541 cccttccaaa agatattctt ccttttcttc ccgatatttc tttttatgta gtttttttaa
    18601 ttctttgatt cttggatttt ttgctgattg gatctctttc acattcctca cctccccatg
    18661 attatatcat ggaataggtg cttgagcttg tttcatccta aaaaaatcgg tatcattaat
    18721 ttataaaata ggaaagaaag gtgacgaaca tgcgcaaagt taaaatgaac gtccaaggac
    18781 gcgtccaagg cgtaggattt cgctacatga ccaagatggt cgctgatcaa ctaggcgtga
    18841 ctggaacggt aaaaaacgaa gatgacggct cagtcacgat cgaagcaatc ggcaatgacg
    18901 acatcatcca gaaatttatt gaagaagtca agaaatctcc gagcccaagt ggacgagtgc
    18961 agtatgtgga tgtccaagaa gacccgatga ttgaggaacg aaagaaattt gatgtggtgg
    19021 gataaggttg tgaaaaagct ggtctgcatc aagcattaag gacaggttgt gaaaaatagc
    19081 tctccatatt tttcaacagg ctggacttaa tgccgtagat gcaagctttt gaacaccgtc
    19141 aataaggttg tgagaaagtc gcttagtttt gagtagtaag gagaattttg tgaaaatggc
    19201 tttccacatt tttgcataaa atttgactta ataccgagaa actgactttt gaacaccgtc
    19261 gataaggttg tttttgagac gctttgcctc aagtattaaa gataggtagt aaaaaagctg
    19321 atctataact tgcaataaat ttgcttaacc catattttcc agacagaaca aaaaagtttt
    19381 tagtttttta aataagaaag aaacacttgg aatcactctt ttctttccaa gtatttcttt
    19441 cttgattttt tgtctttttt tcaaaatttt tcgctacgta aaagaacgaa tatttatatg
    19501 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
    19561 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
    19621 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
    19681 gacacttcgg gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
    19741 ctagttgaga atttcaattg gtcttatggc tgggcagtta ttgcaatgac tgtgatcgtc
    19801 cgtatcatca tcttgccact aggtattagt caatcgaaaa aaacaatgat ccaatctgaa
    19861 aaaatgcaag cgttaaaacc acaagttgaa gcagcccaac aaaaattgaa agctgcaaca
    19921 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtataccg cgaaaacgga
    19981 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
    20041 gccttgtact ttacggcacg ttatacagaa ggtattcggg aatcatcttt ctacggcatc
    20101 gatttaggct caccaagtat ggtacttgtt gtcattgcag gggtcgccta tctgcttcaa
    20161 ggatacatct caacgatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgcta
    20221 atcgtctctc ctgctatgat cgtcttcatg tcgatcagtg cgccagccgg tgttacactt
    20281 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
    20341 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
    20401 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
    20461 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
    20521 cagaagcgga aataaaaaca taggacaaaa aagatgagag ctaagccctc atcttttttg
    20581 ttactcttcc tcttctgcta ttccattaat taattcgttg acagagacaa tgctttcaca
    20641 tcctgcacga acaaactcgg gctctgaacc aatcatttgt gagttgataa attcaatgac
    20701 catcggaaga ttcatcccag cataaagagt aatctgttgt ccttccatta ttagtttaga
    20761 aatgatattt gcaggtgtac cacctaaaag atcgcatagt accacaaaat catttaacga
    20821 atctgtgaca gtgagaaact tttgtttgta tgtttcagtg ccatcttctg gtaataaagg
    20881 taacgtgtag atatcctctt gaggccccat gatcatttct gtactttttt tcaattcctc
    20941 acaaaatttt ccgtgactaa tcaataccaa ttgtctactc atttttcgct ctcccttatt
    21001 tcgaaatcac acccaatgca gataaagcaa cacacacaat taatacgata aaaatcgctc
    21061 gagtaggagt catgtttttc tttcctaata accaataaac accaccgacg atcccagcag
    21121 gtaaaatttt aggtaagatc atatcgatat agttttgcat attcaatgtc acatcgccaa
    21181 tcgttggtgc ccatgaaaat ttaacattga tcattgtcgc aactaatgcc cctaccatga
    21241 atacccctaa taaagtggct gcgtccgtta atgcagttaa gcgagattgc atagtagtaa
    21301 ctaaggaaat tccttctttg tatgcaaatt caagttgctt ccaacgaaaa accatgacaa
    21361 cgatctgagc aaaaatccat ataaacacac ctatcggatt tccatcagtt gccatattcg
    21421 ccgccaaagc cccaaaaatc gttggaatca aagcagcaaa tacggaatct ccaatcgctg
    21481 caaaggaacc catcaatcca gctttcagcc ccgatacggt ttcctttgaa gcaattccct
    21541 ctttttcttc cattgcaaga tcaatcccag taatgattgt attaaaaaaa ttagaagtat
    21601 taaaaaattg cgtatgtgtt ttcatcatct cttttaattc tggtgtattg tctccatata
    21661 tttttcttag ttgtggcaag atagtatata aatagccaga accctgcatt ctctcatagt
    21721 tccaacctaa ttgaaaagtg aacaaacttc ttcgattgat ttgcttaaaa tcttcttttg
    21781 ttaatttgta attagatttc gtcatcttcg atttccccct caacagaatg tgatggctca
    21841 ctagctaatg gttgatggtc tttgttttga tcattcttat aactgatcat tgctagtgct
    21901 agaccaatca atgctacagc aagcatcggc agcgaattga aagttgccgg aagatcttta
    21961 acaacgcttg ccacacttgt tcctaataat tgaacattag agaataacgt tgctaataat
    22021 gccgtgatcg taaatcctaa aataagataa gatagatgtt tttttactgg taaatagcgc
    22081 agaagaatgg caaacccaac agctggtaaa acagctcctg ctactgaaag tccatcgcct
    22141 agccatttta gattcccgtt taaaacagaa acaacatttt caactaatcc accaccaaat
    22201 gctaaagcta aaaatacagg aatcatacga gagagcgacc aaggtaaagc tcccattaag
    22261 aaattgcgtt cgattgcttg ataattcatg tcttctacgt gacggtcaat acgatgggca
    22321 aagtatgtgt tagcgaatct agctaaaata tccaattgga tcattaagct tgctacaggc
    22381 actgcaatag cagcaatcgc ttgttctgga ttcattccaa gagaaatcga gaaggcagtt
    22441 gctaaaatcg tcccagagtt ggcatctatt tttgatgcgc ctccaaacgt ccccactcct
    22501 aaaactgtca actgcatact gccaccaata atcaaacctg cgtttaaatc acccattact
    22561 aaacctgcat ataaccctgc aaacactggc gcactcattg aagaatagat ctgtaattca
    22621 tctaaaattt gataacctgc atataatgtt aataataaga tctgccacca ttgaatatcc
    22681 atggatcatt cctcctattt gattaaaaga ttcataaagt cttctgcttt atcgtttggt
    22741 accatttgag caattaaatg tataccaagc tgatctaatt ttttaaatac ttcgatatct
    22801 gcatctacca cattgattga ttttgtaatg gaccgtgttt cattcgtttg tgacatattc
    22861 cccacattta cttctttgat aggaactcct ttttctacta aagataagat tcgatctggc
    22921 ttttttgcta cgatcaatac tcgttgagag tcatatttgc cagctaaaat atttgttgct
    22981 gctttttcga ttggcaaaat gcttaatttt acccctgctg gagtcgctaa cttcaatcca
    23041 cttttttcaa ttgtgtttgt ggctacctca tcatccacga ccatgattcg actaatattc
    23101 agtttcgttg tccaaagatt tgctacttat ccatgtatca aacgtccatc gattcttaca
    23161 ccaataattg ccatcatgca ttctccttat ctattttttc tatttattgt tcaattaaaa
    23221 ctgtgacatc atcaaatatc ccttctgttt caaagataac gttttcattt tttctttctt
    23281 atatttcatt tttaagctaa gaacaaattc cttcccaact aaagaaaacg ttttctttta
    23341 tatttaagtt catttgattt tcttaacttg aatgtgtttc atcaacatcg taactttcat
    23401 agggtcgatc cagccagttt tctcttgttg cgcgtttgcc ataccacaag ccatagaaaa
    23461 tgcgagaatc tcttcgattg attgcctttt tgataacgca tgggccgatc ctgcaagggt
    23521 cgcgtcacct gaaccaacag gattaacaac tgatatttta ggaataatga cttcgtaaaa
    23581 acactgagca acttttgcca cagcacctct ctctcctaaa gaaacaacaa cccatggcac
    23641 tccttcaaat attggatgag ctaataagga ctgaattttt tctaattgaa tcgaagaaca
    23701 gatacgttgg ccaatcagtt ctcctaattc ttccagattg ggcttgataa gtagtggctt
    23761 ctccttacct tccaatactt caagcaaaaa tttaccagaa gtatctagta atatgtcttt
    23821 ccctttttta tcagctaaag caaccaattg cttatagtaa tcaagagggc atccttgggg
    23881 taaactacct gagatcgtca taatatctga tatttcgagg agctgctcga aatgatcggt
    23941 aaatgtctgt tgttctttct ttgttatgaa ggggcctcgt tccaaaagct ctgtttgtct
    24001 cgaactatgc aggatagcaa tagaatccct tgtctctcct ttaattggaa caaactgatg
    24061 catgatccct aactgatcta gctggttctt tagatattca ccgtgctggc cacctattaa
    24121 accagtagct atcacctctt ctcctaataa atttagaacc ctcgccacat tcactccttt
    24181 tcctcccgct gttttattga ctgtttcaac tcgattgact ttgtcgaggt ttaattcttc
    24241 aattgtatac gcgatatcga tggaaggatt caaggtaact gtcgtaatca tttcatcttc
    24301 acctttttgc tttttgtttt attgaaccaa ggggtagcgg tttcatttat tactttattt
    24361 aaagtctcga tgttttctct cccatttgtt cttaaccaat gaatagctcc gtcttttcca
    24421 ttttcgacgt atgctttgac cccatctttc catgtcgcac gtccacacaa tacaccattg
    24481 aaggtggaac ccgattcatg agcaaaaatc agtgtttgtt gaaataattc tgttgaaaca
    24541 cccccactca aaaaaatgaa tggtaatgga gtcgcttcac tttgctcctt aaagaaggca
    24601 gcagcctctt ctttgctgtg aataaattca cctgtggaat agccattcac ataattcata
    24661 ttgactggta cttctacttt caacacatca actttatatt ttggatcaga aaattctttc
    24721 atcatctcaa taactttgtg gggcttgact ttcgcatact ctggagaaga actatcgctt
    24781 atttgtgcat cataagaaac taactccaaa tagaagggac gattttctcc ttcgcactca
    24841 ctacctaaac gttcgatgaa cacatgcttc aaatgattga tttcgggtgc ttcatcaaca
    24901 tcgtagtaaa gtaagaattt tactgcatcc gcttgctgtt ctttcaatct gagagaagac
    24961 caatccgcta ataaatcagg tagacgacca ggcgtagttg cgtcatagcc ggttttctca
    25021 taagctaaca ataaccccgt ctcttttgct ctgacttttg ctgctggcaa tccatattcc
    25081 ggatccaata aaatagcaga agcatagggt gtcagctcag ctgatactag ttctttgaat
    25141 tcactgattt ggtcttcact tggctctttt cccaacgatt tgatcatttt ttttagagca
    25201 ccacgctgat cgatcgctaa tgcactaata atcccatctt ttgttgatag tctctccatt
    25261 gccctatttt tttcttcatt catctgtcat ttctccttcg gtttcatact tatgaataat
    25321 gacgcccttg actactcgat tgaccgtgcc tgttggagat ggtgtatctg gtttattagc
    25381 tactttgatt gaagtataga gtgcaatgat ttgtgcagtc ataatcatcg ctaatgcaag
    25441 ataggcatcg ggcaatttac tcaccgagtc ttccaatagc acagtcatac ctgagaaatc
    25501 aatagtaccc ggttgcgcaa tcgcaatgac attggcagtg acccgatctt cttttatttc
    25561 ctctaaaata tctaagtcat aatttcgcgt atatggttga ttgctcacaa aacctacaac
    25621 gagtgtctcg ctatttaaaa aagactttgg tccatgacga aaccccatcg aagaatcaaa
    25681 aattgtagca actttacctg ctgttaattc taaaattttt aattgtgctt ctcttgtcgc
    25741 acctgccaaa cttcctgaac ccagataagc gatccgttca aaaaaatcag gtaataactt
    25801 ttgaatttct tgatctcttg aaagaagatc ttgaccgatt ttaactaatt gttcaagata
    25861 tctttctttt ttctccattg ctgtttgatc aaagatccat aaagcactca ataacataca
    25921 cgtaaaactt cctgtcatag caaaacctgc atcgtttgct ctctctggca tcaataacag
    25981 ataattctgt ttatcatcct gtgcgttttt tgccaacatc ccctctttag cacaagtaat
    26041 cgtcaaatga aacaatgttt caacttgttc atttgcaatt tgcacagccg ctacactttc
    26101 tggactgttg ccactgcgag caaatgaaac taataaagtc ggttcatttg gaaacaaaaa
    26161 ttcttttggt gaagctacaa tatctgtcgt gccaaaactg tggaagataa aaaactgatt
    26221 gtctccatgt tcatttagat agggtaagag cgtatcccca atatattgag acgttcctgc
    26281 acccgtaaaa ataacacgta ttcttcttcc gtttgcttct ttttttattt gatcaaaaaa
    26341 tagagctaaa ttttcttggc tttgcatcaa tctatcgatt gtttctttcc agagatctgg
    26401 ttgttgtttt atttcttgtg tcgtgattgc tgcacctatt tgttttaatt tgttcttcga
    26461 tagctcaaac atgttgttct ccctctcaat cattttcgga tatgccgaat tttataatga
    26521 aactggtccg ctcttgctac actatctgta tattcgataa tctcattttt cacgttatag
    26581 gttatcctcg tcagatgtaa gacgggagcg ccatcagcga ttcgtagcac aacagcatct
    26641 tttttttgca cgatacttgc ataaaactct tcatcagcta attgaacttg ttgttcataa
    26701 tcctgtgaaa acacatcata caacggttta ctttcaagta acggcaaatc aagtcccata
    26761 aatagtttcg ccggtagata agaacgctca accatcaatg gctcttcatc tgccaaacgc
    26821 aatcttttaa gtttaaatac agtttcacct aaatggatgt tcaaattctt agcaattctc
    26881 ttattagctt ccatttgtct aaattctaaa atgaccgtct tagggacgcg ccctatttcg
    26941 cgcatttctt ctgtaaagct atatgctcca gctaagttcg atgacttatc agacaaatca
    27001 gagacatagg taccttttcc atgtcttcgg taaatataac cttgattttc caattcctgt
    27061 aaagccagac gtacggtggt acgactcacc ccatagtgtt gacaaagttc tctttcagat
    27121 aacagcttat catgcggagt catctgtgtt tcgatacgat ccttcaataa atcaactagt
    27181 tgataataca atgattttcc tttatttgag ctctccataa aaatcacctc ttctttactg
    27241 gttataacca caacacaaga atagtgaatt attaatcatt tgtcaaaggt tttttagacc
    27301 aaaaaagcta ttataacagc tctttaaagc tttatatctt gaatagacaa agatacctca
    27361 aaaataccag ttaccaataa aagaacagaa aaaaagacga accacataag cgatccgtca
    27421 aaatggtcta acttatcgag cagcgtgatc cacattaatc cctatgatat tcctacaact
    27481 atcgttttat tacttccaat atcatttaca acaactaaaa atagcttatt aatgacaaat
    27541 gttattatta gttttagata acttttgcag ttttatactt tttttctata
//
LOCUS       DARBDN010000025        27400 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000025 DARBDN010000000
VERSION     DARBDN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.025"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            144..1622
                     /locus_tag="SCH06_001132"
     CDS             144..1622
                     /locus_tag="SCH06_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077726.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            1899..3959
                     /locus_tag="SCH06_001133"
     CDS             1899..3959
                     /locus_tag="SCH06_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEG1077727.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRREESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            4042..4611
                     /locus_tag="SCH06_001134"
     CDS             4042..4611
                     /locus_tag="SCH06_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1077728.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4786..5592)
                     /locus_tag="SCH06_001135"
     CDS             complement(4786..5592)
                     /locus_tag="SCH06_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077729.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5730..7244
                     /locus_tag="SCH06_001136"
     CDS             5730..7244
                     /locus_tag="SCH06_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HEG1077730.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7647..8630)
                     /locus_tag="SCH06_001137"
     CDS             complement(7647..8630)
                     /locus_tag="SCH06_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HEG1077731.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8635..9282)
                     /locus_tag="SCH06_001138"
     CDS             complement(8635..9282)
                     /locus_tag="SCH06_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1077732.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(9367..9999)
                     /locus_tag="SCH06_001139"
     CDS             complement(9367..9999)
                     /locus_tag="SCH06_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEG1077733.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(10015..10566)
                     /gene="coaC"
                     /locus_tag="SCH06_001140"
     CDS             complement(10015..10566)
                     /gene="coaC"
                     /locus_tag="SCH06_001140"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEG1077734.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10563..11300)
                     /locus_tag="SCH06_001141"
     CDS             complement(10563..11300)
                     /locus_tag="SCH06_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEG1077735.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(11297..12286)
                     /locus_tag="SCH06_001142"
     CDS             complement(11297..12286)
                     /locus_tag="SCH06_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEG1077736.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12544..13086
                     /locus_tag="SCH06_001143"
     CDS             12544..13086
                     /locus_tag="SCH06_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077737.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            13103..14188
                     /locus_tag="SCH06_001144"
     CDS             13103..14188
                     /locus_tag="SCH06_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077738.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            14200..15006
                     /locus_tag="SCH06_001145"
     CDS             14200..15006
                     /locus_tag="SCH06_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077739.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            15007..15834
                     /locus_tag="SCH06_001146"
     CDS             15007..15834
                     /locus_tag="SCH06_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077740.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15831..16904
                     /locus_tag="SCH06_001147"
     CDS             15831..16904
                     /locus_tag="SCH06_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1077741.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            17332..20028
                     /locus_tag="SCH06_001148"
     CDS             17332..20028
                     /locus_tag="SCH06_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1077742.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            20105..20593
                     /locus_tag="SCH06_001149"
     CDS             20105..20593
                     /locus_tag="SCH06_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1077743.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            20605..21099
                     /locus_tag="SCH06_001150"
     CDS             20605..21099
                     /locus_tag="SCH06_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1077744.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            21120..21929
                     /locus_tag="SCH06_001151"
     CDS             21120..21929
                     /locus_tag="SCH06_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1077745.1"
                     /translation="MYDAFVVALAVFIGIAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21926..22747
                     /locus_tag="SCH06_001152"
     CDS             21926..22747
                     /locus_tag="SCH06_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1077746.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22798..24897
                     /locus_tag="SCH06_001153"
     CDS             22798..24897
                     /locus_tag="SCH06_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HEG1077747.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24894..26012
                     /locus_tag="SCH06_001154"
     CDS             24894..26012
                     /locus_tag="SCH06_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEG1077748.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            26051..26929
                     /locus_tag="SCH06_001155"
     CDS             26051..26929
                     /locus_tag="SCH06_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1077749.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            27120..27272
                     /locus_tag="SCH06_001156"
     CDS             27120..27272
                     /locus_tag="SCH06_001156"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEG1077750.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8763 a         4695 c         5730 g         8212 t
ORIGIN      
        1 aatattctca aaaaaaagat aaaaaatgag aataactgat gaaaaaacaa gcataatcca
       61 tcataaaatc agtataggtg aaaagatgaa ctttcatctg catatcaagt aattggtatg
      121 aggcattttt tgaggtgtag gatatgaagt tggattacct tatagaagag gaagatagag
      181 aaaaactgct gctagctaga tatttagaat ttgagaaaaa gaattatgta gtgctgccta
      241 agttatatga aacattaggt ttgtctaaat ttaaaacaag aaattatatc atagaattaa
      301 ataaagaatt tactgaattc aaaacaaagc cagagatcca aatttcagaa gaagcagaga
      361 tccatgtcga acgtctgaat ttgacggata tcaaaaattt aagaagaatc tactttcaac
      421 gatcaaaaat tgctcgactg ttaacggaga tcgtggattc aaaagtaacg atcgaaaaat
      481 ttgcagagaa tcatttttta agcatatcaa gagcctatgt aaaaagaaga gaattagtct
      541 cttttcttga acagcatcaa ataaagttaa agaaaaacat attagttggg gaagaaataa
      601 acatacggaa cgtattattt ggggtatatt tcggggtctt taatggtttt tctatgccat
      661 ttagagaaag cgtcatgaat gaagcaaaga gtatcgtgca atattttgaa tatctgttca
      721 atttaaaact gtctgcaaca aaacgaatca aattcaattt gctaaccact attagtttgt
      781 tgagggccta tgggaatcaa ccaatcggaa aacgtttctt ttcagatgaa tactttaaga
      841 gctcagaagg aatgaagatc atcaaggatt tatcacatat ttcttttctt catatcccta
      901 aagagcagat cattgatgag atttcttata tcatgttgtt tttgatcacg gaagaagaat
      961 ttgaattaga tggcgcattt ggacttgcgg aagctcattt tcatgatatc cacatgatta
     1021 gtcaaaaaat gtcagtggaa ttgattgatc aattaccatt ttcgattgaa atctctgaag
     1081 aagaaagact atatatacga aaagaacttc gtatgggtat gatgcatgtc aatcgaaaaa
     1141 attggatatt cgactttgag atgactagct ttacgtctaa aaagcagcta cagtttttct
     1201 tcgagacgta tccaatattc agtacagcaa tccaaaaggt catacaagag aataaacgct
     1261 atttcttggg aaaagatgaa cgtttcatga ttcgcttatt ttatgattat ctctttttat
     1321 tggtcggtat ttgtccggta tcatattttg aagcaccgat tcatgtctgt attgattttt
     1381 cgcaaggatc tgcttatacc gattacatta tttctcaagt gaaaggattt aaaaattaca
     1441 atattgtgat tgagagtcga atcacttctc gtacgaatat ttatttatct gattgtttac
     1501 ttgaaaaatt taataaagaa cagataattt ggaaaaatcc accgactcca gatgactggg
     1561 aatattttgg aaataccatc atcagagaaa aaaatagaca tttaactgaa aaaatcagct
     1621 agtatttatg gatggcagct ttgtctcaca tatttattag ctgatttatg tttttttcaa
     1681 agaaaaggta actagatata actagatata actagatata ttacttaaca aaattaaaaa
     1741 gtacataagt tattattccg attttcttga aacaataaaa aatcaaaaaa aatactctcc
     1801 taatagtcca tcttcttttg attttattta tataatgaaa tcatcttatg aaaattacta
     1861 cttcatgttt agacaagagt agggaggact aagaataaat gtgttcaaaa agacgttcaa
     1921 aacaactaaa taaacacgct tgtcgtttag ataaggaacg gtcgtgttct gaaaaacact
     1981 acgttaagtt tatgatgcgc acgatgctga tcagtttatc tgtaggtgtc tatatgcatg
     2041 tacccgttca ggcaacgaca caaaccatca aggtcgtacg tacctctgtt tctgagacca
     2101 ctgattcccc tatcactatt actcatactt tcactgatgc aaatggaaaa cagctacttc
     2161 ctgcattgac ttcctataat aaagtcagtt atcctccaac gataaaccac tactggttaa
     2221 ttcctaacaa aacattatgg acatcggaaa ccggaagcag tgtgccgctt tctatctttt
     2281 ccgatatgac tgatcctaca aaaggtgatc agttaaaaca gatcactgat attttgaatc
     2341 atgctttgac agatataaag gacggtggaa gcgcacaagt ttcttatgta tatgaaaaag
     2401 attattcaca gtttgaaaga aagaaaatcg atgttctggc agggacaaaa gtttcgatat
     2461 ctgatctggt agaaaggctg aagaacgcag atggaacaca aggagatatg tccaaagtaa
     2521 tttcaaacaa tgggaatatc gtggatacga ctaatacagg aacatctact atttccttgt
     2581 cctattttga tccaattgct ttaaaaacaa tgactgcatc tgctgtgatc catgttcgtg
     2641 ctgatcaaac agctatcaaa ggaaaagatc ttcacttaag aacaggagag agttacgccc
     2701 ctaaagatct tgttgaatat gtaacaaaaa gcgatggaac ttcaggaaat aaagaagaaa
     2761 tcaaaatgaa cgggacagta gatactacaa ctccgggaga atatcccgtt gtattaactt
     2821 atatagactc gaaaacatca aatgtggcag aaacaacagc tgtagtttat gtagaagcat
     2881 ctgctgcttc atcgactgtc atcactcatt ttatagatag tcaaacaaat aaagaacttc
     2941 aagcagaaac acatatgagt agtgtaaatc gtattcctga tttgcgccta cctgctgaat
     3001 tttctgatcg agtgccaaat atagatttat cgacttatga acaaaatggg aaagtcactt
     3061 ctatttctga ttggatgcaa gcaaacggat tagacagaaa aagtcactgg tcggagatcc
     3121 ttgaagtact tcactcagaa ctgatgaata ataggaagca atcaggaggg gaaattacct
     3181 ttacttatgt ttatatacca gacaatcgtt cattagaagg tcatgatctt attgttcatc
     3241 caaacgaaaa aataaacaaa gaagagttga tccaatcagc aacaaattcc ttaggtaaac
     3301 ccgtaccgtt aaaggatgta tcggttacaa tcaatgaagt accattggag gatggttatt
     3361 tgaccaaaca aacaggtgat tttacgatta tgtatagtta tcatgacccg tattcactcc
     3421 aagaactcca tgctcagtca ctattacatg ttttaccatt aaacaaacag atagatcaaa
     3481 aagaacaaaa aagacgagaa gaaagcttgt cagaaaaaaa acaacaaatg gctcatgcag
     3541 tttctccaac agggaaagta aaacaaacaa gaagcctaga gttagcaaga atatctagaa
     3601 aaatctcaga atctaataaa acgataaggc aagaagctca tttggcccca caagtttctg
     3661 gattggaaaa tgaaatttta gagcctaaaa taaaacaaca atcagaaaaa gaatttgttg
     3721 ctaaacagtc ggaagatcag aaggaatcag atgaccagaa ggaaacgaag aaaaaacgct
     3781 tgtcaactat tgattccacc gatgagcatc tgcagccgca agtaccactt cctagtccgg
     3841 gaacacccgc acctggtgga ggtattcctt cttctgcttt aggagatttc atgcgaggta
     3901 tggcaggaac atgggtatac gctaatcgaa atgaatttga cgcagatgac tggttctgat
     3961 ttatatctct atctgttata gtcaaataag tagctgagtc atatgttatt tggcataatg
     4021 gagacgagga gggatagaaa aatgttagat aaaacgttac cttacgcaga aatctggatg
     4081 acaagaccac ttcaacaaaa tgttccaatc acgcctttag cggaaggttt tgaatttcga
     4141 ttttatcaaa aagaagatga atctgcttgg gcggagattg agacttccgt tggggaattt
     4201 caaacgacag atgaagcact tgagtatttt caacaaaact ttgctcctta tcctgaagaa
     4261 cttgaaagaa ggatgttttt tgtagagaca aaaaaaggag aaaaagtagc aacctgtacc
     4321 gcttggcgaa aaaaatcaag agagcaagtg tatccggttt ttcattggtt agcagtgaaa
     4381 ccagattacc aaggaaaagg gctcgcaaaa gcattgactg ccagagtctt gcaagaattt
     4441 cctaccctcc atacggacgg accaatctat cttcacacac agacatggag ccatcaggcg
     4501 attgctcttt ataaaaaaat gggttttact tttattgctg aaaatctaga cggcacacct
     4561 aatccagatt atgaaaaagt tatgcaggtt ttaagtaaat tagataaata acgaaatggt
     4621 gaaataagtc ctcagtattg ggataaaaaa cgaaatagtc attcctcata tcttactttt
     4681 ttgagttaat actatcggat aactaatggc atgccataca ttcaaaaaag aaggggcagt
     4741 gacaaaagta ttgtcactgc cccttctctt gttttttagc atgttttatc gtttgatttt
     4801 tttaggaata aaattcttga tgaacgtaaa tttttggtaa tcgtttcgac tatagaggta
     4861 accaaataca ctgaaaacaa ctgctccaat aaaattaaca aataaatcct tcatagtatc
     4921 catgattccc acgtctaagt aaccattttg gatgattgtt ttatctgttt taccatctgc
     4981 attttgactt tcaatgattg tccgagtgat atctggaaca tgatagacag tgtttccgtc
     5041 tttacttaac tccacactat tgatttgctg gatgatcgta tctttttgca tatcgaattg
     5101 cagtaattta tctgctgaaa attccacaaa ctcccacata acaccaactg tcatcgaaaa
     5161 acagaaggaa acaactgcta gtaataaagg agtcaagttc atggtttttg tatttttatt
     5221 gagcaaataa acaagggaaa agccgacacc cccagctaaa aatccgctga atgcatgtag
     5281 aaaagtatcc cacattgaaa aatagccata aaaatcactt aactctccta aaactgttga
     5341 actaaaaata aaagataaca aaatgatttc tagcatattt ggaatctgta tctttaatat
     5401 cttttccaga aaataaggga tttcaaataa aattaatgtc agtaataaaa gcattgtatt
     5461 tccccagtgt tggttccaga cctgatccac tagcataata acgacgatga tacgtaataa
     5521 aatatagatt ccgtttgtga ttctacctgc agtttttgta ctgttcgtaa aaaaggtttt
     5581 caaatgattc ataaaataac tccttcatgt atatccttaa ttatactaag aagcgtgtgt
     5641 ttaccaaagc tatatgactt aaagaaaaac agagttgata ttgtgaaaaa aatcacttaa
     5701 tatagtataa ggagaaaagg gggatacaaa tgaaaaaatt agttgctggt ttattaacag
     5761 ccgttgcact tcttgctatg agcgcatgcg gcgcagatca gaaaaataca gcgcagacaa
     5821 gttctagtac gaaggaatct gccgaagtat catcaggcgc ttctgaacaa gtatatacag
     5881 atccaaaaga aatgaaagaa tcttatgatg tcgtgattat tggagctggt ggtgcaggga
     5941 tggcagcagc tatcgaagca aaagatgctg ggttgaatcc agtaattttg gaaaagatgc
     6001 ctgttgccgg aggaaacaca tctaaatcat caagcggtat gaatgcttca gaaacaaaat
     6061 ttcaaaaaga agaaggaatc aaagactcga atgatgcctt ctatgaagaa acgctaaaag
     6121 gtggtggagg aacgaatgat aaagaaatgc ttcgatactt tgtcgatcac tctgctgatg
     6181 cggtcgattg gctagatcaa aacggtatca aactggacaa cttaacgatc actggaggga
     6241 tgagtgaaaa gaggacacat cgtccgtctg atggctcggc tattggtgga tacttagtgg
     6301 aggggttatt gaataacgtc catgagcggg aaatccctat ttttgtcaac gcagatgtga
     6361 cagacattaa gaaaaatggg gaaacggtca atgaagtgac tgtacatgtt caaggagaag
     6421 aaccaaaaga ggtcaccgga aaagcaatcg tagttaccac aggcggtttt ggtgccagca
     6481 aagaatttat tgaaaaatat cgtcccgatt tagctgatta tattacgaca aatcaagaag
     6541 gatcaactgg agatggtatc accatgattg aaaaattagg tggacaaacc gttgatatgg
     6601 ataaaataca aattcatcca actgtgcagc aggatgaggg ggtcttgatt ggtgaggttg
     6661 ttcgcggaga aggagcaatc ttggtcgatc aagaggggaa aagatttgtc aatgaaatgg
     6721 atacaaggga taaagtatct gcagcaatta cagcattgcc tgaaaaatca gcttatttga
     6781 tttttgacca aggcgtgcgt gatcgtgcca cagctattga attttatgac caaaaaggat
     6841 atgtcacaac tggaaagaca atggaagaat tagcagaaaa aatcgattta ccaaaagaaa
     6901 cactagcaaa aacagttgat ggatggaata cggatgttgc ggagaaaaaa gatgctcaat
     6961 tcaaccgtgc cacagccatg gaacatgact tatcgtctcc gaattattat gcgatcaaaa
     7021 tcgcaccagg aatccattac acgatgggcg gtgtgaaaat caatacgaac actgaagtat
     7081 tagataaaga aaaccagcca attagggggt tatatgctgc tggtgaagtc acaggtggct
     7141 tacatggaaa caaccggatc ggtggaaatt cagttgcgga gatcattatt tttgggcgac
     7201 aagcgggcat acaagcagct cgatttgctt cggaaaatga atgaaataga acgtaaataa
     7261 aaagaggttg tgaaatcagc gttttgagct aataccgagg gtcagctgat tgaacactgt
     7321 ttagtgaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaagtaaaa
     7381 acagcttctt atgtttttaa cttggttgga cttattaccg cagatgcaag cttttgaaca
     7441 ccgtttattc ggaaaaagag cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta
     7501 aacacgtata aacggcggaa gcagaagaaa ttccttcgga aataagctga aattcacaaa
     7561 aatttgaaaa gcaattttcg tgaatttctt cttatttctt ggagttaaac gcttctgtcc
     7621 cagcctcttt tttgatcagc atgattttat tcagttatct tcaaaatgat ttttccgatg
     7681 tttttgtttg cttccatata ttcatgcgct tgtttgactg cgctgaattg gaatgtacgg
     7741 tcaatgattg gccgaatctt gccattttct agaaaaggcc cagctttttg cataaaagtt
     7801 tgtgcgagct ctgctttata ctgatcactt ctaggtgtca ataatgtacc aagcagttgg
     7861 acacgtttcc caatcaatac accaaggtct atctcaggca cgatggtccc acctagcata
     7921 ccaatcaaga cccaacgtcc atcaacggct atagaagcta aattcttttc ccagtaagaa
     7981 gcgccgatga aatccaaaat aacatcgact ccccgacctt cagtgatttt tcgtacctct
     8041 tcttgaaagt cttgtttttt atagttgatc aattcatctg caccaagttc tttacaaaag
     8101 gcgagttttt cttctgatcc tgcagtaacg atgattttcg cgtgagaaag ctgtctagct
     8161 aattggatcg ctgctgttcc cacaccactt gctcctgcat ggatcaagac agtttcgcct
     8221 tcttgtaatt ttccaagcca gtaaagtgtt tgataagcag tcaaaaaaac ttctgagatt
     8281 ccagcagcag aaacatagtc tagcgtatca gggagaagga ttgcacgatc ggcaggcatc
     8341 acagcatatt cggcataacc acctagattg actaatccgt atacttttgt cccaggagta
     8401 aaagtggaga tatcactttt attctcaact acctctccag ctacttcgac tcccaaaata
     8461 gggtagggag gtttcaaaga gactgattct cttttcataa tatctgttcg attgacagct
     8521 gctgtatgga ctttgatcag taattcgcct tgttttggtt taggaacagg cacttcaatt
     8581 tgttctaata catctacaga accaggatgc ttgattgaaa tggcacgcat ggatctattc
     8641 ctcctttgcc cattcttgga atgctgtatt caactctttg ctaccttcag aaagtactag
     8701 agtcgtacga gaaatatccg tttcttccac tagagcggca agtacagcag caactgtaga
     8761 gcgagtgatc gtttttgatg ccttctcatt aggcttagtt aattgaatgg aagtaacttc
     8821 ttcatcgtta gtcaatgtga ctggttgaag aatgacaaaa tctaagttag ttcgtttcag
     8881 ccattcatct gcataatgtt tagtaatata ataatctgtc atggactcag gccattttgc
     8941 tggttcatct gcataaacag cactgaccat cagatagcga gagacatgcg cattttcagc
     9001 tgcgatcact gttttgattg cgccatccaa gtctacttgc agaagattct ttccttgaga
     9061 gccggcagca aaaatcaata catcgatgcc tttgaatgct tcggtcattt tttccacgga
     9121 ccaagttaaa tcaaaagaga catacgaaac attctctttt tttactaatg tttgggaagc
     9181 aacatctctc acccctgcaa aaatttcatg ggaacttgga gctaaatctt ttatcaggtg
     9241 tcggccaatt tgtccgtttg cacctacaac aaaaattttc atttggatca tcctttcgac
     9301 gtcaaatctt tccattcaat agtaacacca aaagagaaaa aaatcagaga tcggctacga
     9361 tgactatcag ttagtaagag aagggtgctt gaagtatctt aacaagacat tgcatactgc
     9421 tgcagtcgca agacctgcga cgattccttc aggtatacca cttgtaaaaa taaccgctag
     9481 aatagctgaa taaacagcat ttaaatttgt tccgatgact ttggcataat cttgctggaa
     9541 taaaaagtag atcatattca tcactaaaat cgtattggtc aatgaaccgg aaagtccagc
     9601 taagaataaa gaaacggaat ctgctttttg tttcattagt ttgcgcagac ctttataaac
     9661 gaaataagga accaccccaa tcaagatgcg aggaataaac gcgatcagca aggctttcca
     9721 gcttccatgt tctgttccga tgactgggat aaacggagaa aagacaaaag acaaaggtgt
     9781 ttggataact gtgctacgga tcatgctgat cagtccaaat gtaccgccaa gaaaagcacc
     9841 tagtcttggt cctaaaacga tcgaagcaat gattacagga atatgcatgg ttgttgcatt
     9901 gattggaccg atagggataa aacctaaagg cgtaacagct aataaaatca aaatagctaa
     9961 aaacatcgca gttaatgtaa agttttttgt atttttcata agtactcctt ttttctaagc
    10021 atttctttca ttaagagtca gcatgacctg ttcgatgatc gtctgaatat cagctaaggc
    10081 accttttcca aaatctccac aagctaaaag agattctctt ggttcaattt cctgatagcc
    10141 gacagatctc aatgtttcca gattacgctg agtgatcggg ttttgataca tattcgtgtt
    10201 catggcaggg gcaatcaatt ttggtgttcc cactggaagc gccattgcga ctgttgaaag
    10261 aagatcgtct gcaatgccgt ttgctagctt gccgataatg tttgctgtag caggcgcgat
    10321 gagaaacaag tcagcttgtt ttgctagttc gatatgattg attacctgcg gatttgattc
    10381 ttgcatgacg tctgtatgga ctgcgcgctt cgacagagat tgcaaggtta atggcgtgat
    10441 aaaatgtgtg ctgcttttag acataatcac atctacctgg gcacctaatt tgacgaattg
    10501 acttgtaaga tcagcgcttt tgtaagcaga aatacttcca gtaacgccta gtaagatctt
    10561 tttcattttg attcctccag tctaattttc tcagtaatca atgcagcaat ctcagattta
    10621 ctttgagctt cttccactgt tccatcttta gataagagat agccgtggtg tgtctcgcca
    10681 tggatttccg tcaaatcatt tgcgaaaata aaatcagttt tgttatttat cagactattt
    10741 tttgcgactg ccagaagaga ttcctttggt acatctacta atagtttgaa accaatgatt
    10801 tttgcttttg gctgccattc acgtagataa gaaatgattt ttggtgtttt cttcaaaacg
    10861 agcacaagat gctcggtgtt agaagagatc tttgaaacag tggtatctgt ctgttcattt
    10921 tccgcaaacc aattgtccag ttcttcttgc gttgaagaag tgggtaggtt ttttgccagc
    10981 tgttcttctg aaaaactaaa agcaggagta aaatcactga ctgccatact gtggataatc
    11041 gcatcgtagt gttctttttt cgttagttct tctaattgta aaaataagtc cagtgcagat
    11101 tcgatcgtat aaatcgttat attggagtgt cttttcggtt tcagtgcttg tttcgtagtc
    11161 acgtaatcga ttgtggtatc cggattggca gctaaataat cagctaatgc ttgccctaat
    11221 cgtcctgtcg aatgatttgt aatagcacgt acttgatcga ttttttcagt cgttcctcca
    11281 gctgtgatta gaatcttcat ttatggtcac ctacatttac tagtgttctt ccttggtgtg
    11341 ttccagcaag tagtttagat gctgtttcag gcaattgatc cagagtaatc tcttggacga
    11401 ccagttcatc tgcaatctgc aaatccgcca tctgttgcca taaagaaaga cgttgatcta
    11461 ttggtacatt gacagaatca attccaatca actggatgtt tcgcagaata aaaggcaaga
    11521 cagtcgcgtt tagtttgatt cccccagcat tgccacataa agctactgca ccgttataag
    11581 agatcaatgg aagaagactg cttagctgct cgccacctac tgtgtcgatg acatagtcga
    11641 tttgctgttt tcctaaagct tttgttgtct ctggcagaaa ttcatcaggt cgtacgactt
    11701 gcaaagcacc tagacttttt agccatgtga cagactcttc ttttctggaa aaggcaatga
    11761 ttgactggaa tcctagttta tgtaacaggg ctatcgctgt actgcctaca ccgccagaag
    11821 caccagtaac gacaactttt ttatcggagg tcataccttg acggattaaa gcgttcacac
    11881 acaacatagc agtaaaccct gctgtaccaa ggatcatcgc ttgacgcagc gtcatatttt
    11941 ttggtagagg aactaaccag tctcctggta ctttttgata ttggctataa ccgcctggat
    12001 gggtgacgcc aagcccaaaa ccagtagcaa gtacaagatc ttcttttgaa aaacgtggat
    12061 tgttactttg gacgacagtt ccggataaat caatccctgg agtcatcgga tatgttcgta
    12121 tcacctgacc agactcgctc attgccaatg catctttata attgacatca gaataggcaa
    12181 tttttaccaa gacttcattt tcagccaact cagtaaatgg cagatcactg attgctgtat
    12241 ggaaaacagg ttcctttatt acctgaaaag atcgaaaagc gttcattcgt gagacactcc
    12301 ttttaaaatt ttcttttatc ataccataaa gcctactctt ttattcttgt tcttccgtaa
    12361 atttagacaa aaattaggtg aaaaataaag aatcaaacaa ctagaattta ttccaaaaga
    12421 taaagaaata ttcagcaaaa aaaattttac aaagggttgc ctttttcaat aaatttcgta
    12481 tactaatacg agtggtagta aacaggaagt ttactattag aaaacttcga ttcggaggaa
    12541 attatggaaa ttggtgagaa gttaagaaat ttgcgcatcc aaaagaattt gacacaagaa
    12601 gaactaggcg aacgcacaga tttgtcaaaa gggtatattt cccagttgga acgagattta
    12661 agttcaccat caatggaaac attcttttct attcttgaag tcttaggtgt gactccagaa
    12721 gaattttttc atcaagaagc agcgaatctg caagtggttt attcaaaaga agatcatacg
    12781 gtttatttcg atgaagaaaa cgggtatgaa ttggaatggc tcgtggctga ttcgaatgaa
    12841 aaagaaatgg agcctgtctt gctgactttt gaaggtgcag gagaatataa gacgtttgaa
    12901 ccttcattat ctgaaacgtt tatttttgta ttagaagggg aattagagtt aagcttagga
    12961 gagacggtct atgtggcaaa agcaggacag tcgatctatt atcaagcgac aaaacaacat
    13021 caattaagga atcatctcaa aaaacgaaca aaagtattga ttgttgcaac gcaatcatat
    13081 ttgtaatata gggggtaaaa acgtggggaa accaatcatt tcatttgatc aagtagtgaa
    13141 acgctatgat gatgaaacag tattaaaaaa agtaagtttt gagatcgaac aaggaaaatt
    13201 ttatacactg cttggtcctt ccggctgtgg taaaacaacg atcctacgta ttatagctgg
    13261 attcaccgaa gctacagaag gggacatcta ttttgaaggg aaacggttga atgatttgcc
    13321 agctaataag cgacaagtaa atacagtctt ccaagattat gcactttttc ctcatatgaa
    13381 tgtttttgat aacgttgctt ttggattgaa gatcaagaaa atgtccaaat cagatatcga
    13441 aaagaaggta aaagatgctt tgcgtatggt ccagcttcct ggatacgaaa aacgggagat
    13501 tagtgaaatg tctggtggtc aaagacagcg tgtagcgatt gcacgagcaa ttgtaaatga
    13561 accgaaagta ttgctattag atgaaccgtt atcggcgctt gatttgaaac tacgtacaga
    13621 tatgcagtat gaactgcggg atctgcaaca acgattagga atcacgttta tttttgttac
    13681 tcatgaccaa gaagaagcgt tggcaatgag tgatgagatt tttgtcatga ataaagggaa
    13741 aatcgtccaa agtggtacac ccgtagatat ttatgatgag ccaatcaatc atttcgttgc
    13801 tgattttgtt ggggagagca atatcgtgga cggtgtaatg atcgaagata atctagttga
    13861 gtttgttggt aagcaatttg aatgtgtcga tggcgggatg cgtctaaatg aaccagttga
    13921 agttgtttta cgcccagagg atttgacgat cacgacacca gataaaggaa aactagtcgt
    13981 aacggtcgat actcagctgt ttcgtggtgt ccattatgaa atcatctgtt atgatgaaca
    14041 gcaaaatgaa tggatggtcc attcaacgaa aaaagctaaa gaaggaagca aagtaggatt
    14101 ggcctttgag ccagaagata tccatgtcat gcgtttcaac gagtctgaag aagaattcga
    14161 tgcacgtctt gacagctacg aagaataggg gggacaagaa tgaaaacaat gcgcaggatc
    14221 tattccgtcc cttatatttt gtggctcggt ttattcgtga tcgcgcctgt attaatgatc
    14281 atttatcaat ctttttttga tatgaatggg caattcacgc tgaataatta tctatcttat
    14341 tttacgtcgg ggacatcgct ttctatgacg atcaattctg tatggtatgc atttttgatc
    14401 acgtttttca cgctgatcat cagttacccg actgcttatt ttttaacaaa actgaagcac
    14461 aagcaattat ggctgatgct gattattttg cctacatggg tgaatctgct gcttaaagct
    14521 tacgcattta ttgggatttt cagtgtgcac ggcagcgtga atcatttctt tgattttatc
    14581 gggatcgggc cgaaacagat attattcaca gacttcagtt ttctgttcgt ggcaacgtat
    14641 atcgagattc catttatgat tatgccaatt ttcaatgcat tggaagagat gaatccttct
    14701 ttgatcagtg ctagtagaga tttaggcgcg aatagctttg agaccttccg acgagtgatt
    14761 tttccgttat cattaaatgg tgtgaaaagt ggtgtccaag cagtatttat tccttctctt
    14821 tctttattca tgctgactcg tctgattggc ggaaatcggg tgatcacttt aggaacggct
    14881 atcgaacagc atttcttggt tacacaaaac tgggggatgg gttctacaat cggtgtgatt
    14941 ttaatcattg ctatgttcat cgtgatgctc ctgacaggcg agaagaaaaa aggaggtcgc
    15001 tcataaatga aaaaatttaa atggtcgtat ctttatttag ggatcgtctt tttattctta
    15061 tatgcaccga tcttctatct gattttttat tccttcaatg aaggaggaac gatgaacagc
    15121 tttacaggat ttacttggga aaattatgaa gctgtttttg aagatacacg tttgatcatt
    15181 atcgtattga atacgttcat gctggctttc ttatctgcat tgatcgccac gatcatcggg
    15241 acatttgggg ctatgggaat ctattacacg aaaaaacgac gtgcacggac agcgttgttg
    15301 agcatgaata acatcttatt agtctctcct gatgttatta tcggtgctag tttcttgatt
    15361 ttctttacac tactaggatt cggattaggt tttcagagtg tattgctttc ccatattgct
    15421 ttcagcattc caatcgtcgt cttgatggtc ttgccaaaat tgcaggaaat gaacgattca
    15481 atggtcgatg cggctagaga ccttggtgct aataatttcc aagtagtcaa aaatatcatt
    15541 ttgccttatc tttctccagg aatcatagct ggatatttta tggcatttac ctattctctt
    15601 gatgattttg cggttacatt tttcgtcaca ggaaatggct ttacgacgct ctcagtagag
    15661 atctattctc gtgcaagaca aggaatcagt ttagaaatca atgcgctaag tgcgttagtt
    15721 ttcttgttct ccatgatatt ggtcattgga tactacttta ttagtaaaga aaaccgtcca
    15781 aaacggctga agaaaaacag aagagtacgc gagggggtgg cacggctgcg atgaaaaaat
    15841 tacaatctct gtttttaggt attctcatca ttattgcggt gctgctgctt ggtgttcgtc
    15901 aacttgaaaa aacaagtggc atgagtggag caaaggtact taccatctat aactggggag
    15961 attatatcga tcctagtttg atcacgaaat ttgaaaaaga atatggatac aaagtgaatt
    16021 atgaaacatt tgattctaat gaagcgatgt tcacaaaaat ccagcaaggt gggacaaact
    16081 acgacatcgc tataccaagt gaatatatga tccaaaaaat gatcaaagaa aaactagtac
    16141 ttccattaga tcattcgaag atcaaaggat taaataatat tgatccacga tttttagact
    16201 tggattttga tccagataat cagtattcga ttccatattt ttggggaact ttagggatcg
    16261 tatataacga taaattcttt gatgcaaatc aaattaagca ttgggatgat ttgtggaagc
    16321 cggaattaaa agacagtttg atgctgattg acggtgcacg agaagttatg gggctttctt
    16381 tgaatagttt aggctattct ttgaatagta agaatatggc acagttgaca gaagcagcaa
    16441 ataaattgaa tcatttaaca ccaaatgtca aagcaatcgt ggcagatgag atcaaaatgt
    16501 atatgatcaa tgaagaagcc tccgtggcag tgacattttc tggcgaagct gccgatatga
    16561 tgtgggaaaa tgaacattta cattatgtga tcccaccaga aggatccaat ctttggtttg
    16621 ataatatcgt tatgccaaaa accgtgaaaa ataaagaagg tgcctatgat ttcatcaact
    16681 ttatgctaga accggaaaat gcggcacaaa atgcagagta tattggttat tctacaccaa
    16741 atgaagaagc aaaagcgtta ttgccaaaag acatttcgtc ggacgaacaa ttctatccat
    16801 ctgatgacac gatctcccat cttgaagtct acaaagatct aggatcgaaa tacctaggca
    16861 tctataatga cctattctta gaattcaaga tgtataggag ataatggcaa aactcagtaa
    16921 gaatggggac ttatcaacgt tctaaagagc taaaaatcgt cctttttcta tctgagtttt
    16981 ccaatcttct accaaaagcg gatgaaacgc cgcttttttt gtgttatttt attttttcta
    17041 ccacgttttt ctaccagaga aaagtggaca aaaccattgt aaaatagggc ccgagacggg
    17101 ctagtaaatc taagattgaa aaagttacag aaggataaag taattggaaa ctatgcaaat
    17161 atacttaacc cttctgtaat ctattaataa aactaatata tgaatccagt tcaatatttg
    17221 tagctatgaa aaaacataaa aatcatatta gataaaaact aaattggtag ataaattatt
    17281 ttgtcagata tctgaggcaa atattcgact atttgtgttt caaagtaaaa attggaatac
    17341 aaatatagaa tagacatatt gcagccgata gtttattatg cttttagaca cattaaactg
    17401 gaggaaaaaa tgaaaaagag cgctaaagat cgagtttttg atgagctgat acgactaaca
    17461 gggaatatgt cttctgtcac tgccgagaaa atttcgaaga atctaggtat ctctcgtcag
    17521 aatgccagcc attatttgac gagattagtg gaagataaaa aggtcgagaa attaccggga
    17581 aagcctgttt tgtggaagcc tttagatgaa tatgcggttg tagataatac ggagcaaata
    17641 aacgaagcct ttcattctgt agttggtcat gacggaagtc tgagagaggt cattcaaaaa
    17701 tgtatagccg ctgtcaaata tccgcctaac ggactcagtg tattaataaa tggagccacg
    17761 ggtgttggaa aaagtttttt agccacaaaa atttttgaat acgctatcca tgagcaaatt
    17821 attgaaaaag atgcaccatt tgctatctta aactgtgccg attatgcgga caatcccgaa
    17881 ctgctttcgg caacactgtt tggatacaag aagggggcct ttacgggggc tgaaaaggat
    17941 accgatggtt tattggcaac ggccaacaac ggctatcttt ttctcgatga ggtccatcgc
    18001 ctatcgaaag aaaatcaaga aaagctcttt ctatttattg atactggaaa ctatcgtcca
    18061 gtcggtgaaa atgtaaattg gcattctgct aaggttcgtt ttattttcgc cacgacggaa
    18121 aaaggtgaaa attatttatt agacaccttt gatcggcgta ttcaaattag tgttatgttg
    18181 ccaacttttg aagatcgccc cattcgagaa cgattagagc tgattcaatt attttttcaa
    18241 aatgaagcgg atgttttaca aaaagatatt attgtttcaa gagaagcctt gtctttaatg
    18301 ttatctcatc cctttagtgg gaatattggt aagctgaaga atatcattaa aatcagttgt
    18361 gcggatgtgt atagtcgaac acaagaagaa ccattaacga ttgggaaaaa tgagatcttg
    18421 attcagttaa atatgctgga atccgaagta gaaagcttgc cgattgctag tttattgata
    18481 aagaaaaatc aaaagataaa aacggatcga atcaaaccgt ttgattatga ttcgattttg
    18541 gaaaaaatta ctcagctgat aaatgaaggt aatttcaatg aaaatttttc ttcgataaag
    18601 aatgaagtac agcatttggt gcatcacatt gataaggatt cttttttatc aatgagtaga
    18661 aaattgatga ttcagatgtt tagaaaggtc tgggtatccg ttttaggaaa aacgtacgga
    18721 ttgacgacga gtggacctgt tgcagaaatt attagcagat cctatgtcat ttccccaagc
    18781 tataagacag acttaaccgg gataaatcgt acattagctg caaatctacc tcggacgact
    18841 tacttatgta atcagttctt ggagcattta ccaccgctct cagaaaagga cgagaacttt
    18901 ctaagactgc ttattgtcgt gactttatct gattatgtag atgaatccat cgagctgaag
    18961 ggcctgttgc ttgctcacgg agatagtacg gctagcagca ttcaagcagt agtgaatcaa
    19021 ttatgcggca attatgtttt tgaagcgttg gatatgccag tagagagtaa tgtgtcagag
    19081 attgtcgaat cgacaaggaa tttcgtgaaa cggcaagtga atacagatag tctagtgctg
    19141 atcgtagata tgggctcttt aaatcaaatt tacacacaga tcaagaacga tttaaaaggg
    19201 gagttacttc ttctgaataa tttgacgact tccattgcac ttgatattgg cttgaagatg
    19261 acgatgaatg cgccatttaa acagattgcg gaggatgcag cagacaagta ttcaatcaat
    19321 gttcaatact ttgaaggctt ttctcaaagt agcaacatta tcatttcctg tatgtcgggt
    19381 ttggggattt cggacaaatt gaaagatgtt tttcgtcatc atttatcgga tgaatccatc
    19441 gaagttttca cgaaggacta cagagaacta cgtgaattaa tcgaccaaaa tgatgaaact
    19501 tattttgaca agacaaaatt ggtcatcacg acttcggatc ttccacgttc cttttcaatt
    19561 cctaatatta atgtttatga catcttagac ggtgatggag cagccaattt ggagcatatt
    19621 ttgagtcctg aaatgaagcc ggcagaattt aaccgcttga ttcaggagct agtaaaattc
    19681 ttttcgttgg aaggaattgc ggaccgtttg aactttctga acccaacgat cgtgatgagt
    19741 gaagtggaaa cagtcatttc taaatatgaa aattactatc atttcacttt aaatggccgt
    19801 gtaaaactaa atctctatat gcatacggca ttgatgatgg aacgtttatt cttggctcgg
    19861 acagaaaaat ctgaagaacc gaattatgat ttgaaaccag atgaagatga attttattat
    19921 gtttctagaa gtatttttca atcaatggag atgaaatata attttaaagt caatgcttat
    19981 gagctttcgc tgctctatga attattagga ccgtatattc aaaaataaag tgtctaaaaa
    20041 agtgtctaat ctgttttttt taggttagac acttttttta atgtgaatta acgtgattaa
    20101 accaatgttt ttaaaagttg gcacaggaat tgcttatata aaagtgaaca gaaagaaagg
    20161 aattaaccat atgaagaaaa ttctaatagc gactcacggt cacttagctt caggctttct
    20221 tagcagtatt caattactga cggggaaggt tcaagagatt acggtgatta atgcttatgt
    20281 ggatgagtgt gattttgaac aggagttgaa tgtatttgta aaccaggtga acgagcagga
    20341 tcagattttt gtttttaccg atttatttgg cggaagtgtc aatcagaaga ttaccaaaac
    20401 ctttttggag aaagagattg ctgtaactat tttgtctggc tttaatctgc caattctgct
    20461 cgaaatagta ttggcaacca aggaattaac aaaggaggat attcaggaac tggtaaataa
    20521 atgccaacag gaattaaaga tgaccattct tgatgaggta catgtagtaa atgaagagga
    20581 agattttttt taggaggaag aaaaatgatt aaagcagtgc gaattgatga acgattaatt
    20641 catggacaag tagcgatgac ttggacaaag agtctaaatt taaccgggtt agtagtagca
    20701 agcgatgagg cggctaccaa cgatattcaa aagatgacat tgaagatggc tgcaccatcg
    20761 aatgtcaaag tcattattaa aacagttgat gacgcgattc atttgttaaa agatccgcgg
    20821 gcgaaggaca tgcgcttgat ggttttagtc cctaatgtca aagatgcggt aaaagttgcg
    20881 aaagctttcc caacggaaat cgaattaatg aacgtgggga atgctgggaa aatgacaccg
    20941 ccatcggaag ataagaaaac cttatcaaag gaagtgatgt taacgacgtc agaaattcaa
    21001 gacttaaaag aattagttga actttatcca gataccgttt ttcagcctac accggcgatg
    21061 gaaaaacgtt cagctatctc tattttgagt gatttttaga aaaaggaagg agaaaaatta
    21121 tgtatgatgc atttgtagtc gctttggccg tttttattgg aattgctgga catgaaatgt
    21181 tcgggatgtc catgctgagt cgtccgattg ttgttgctcc gttagcagga gcgttgatgg
    21241 gggatttgca gacggggttg attgtcgggg cgtcactaga agccatcttt atgggtgtcg
    21301 tcaatatcgg aatctctagt acggcggagc cttctttggc tgctgggctg gctacagcgt
    21361 tcgcaatcaa aatgggagga aacgtggatg cgattattcc cattgtcttt ccactagcag
    21421 tattaggatt acagttaatg aatatgattt tttcttttgt atgtggaccg atggctgcta
    21481 aatttttcaa atttgcaaaa tctggtgatc aaaaaggaat catcaatctg cacttcttta
    21541 tgtggtttgt ccactatgcg ctttatgctc ttattccatt ctttgccgtt ttatttggag
    21601 cagatgttgt caaaagcgtc ttggataata ttccagaggt catcatgaac ggattaacag
    21661 tcgctggaaa tctgctgccg gcagttggga tggcgatgct gttacggatg ctttggagta
    21721 aaaatattgc tgtgtggttt ttctttgggg ccgttgttat ggcgtatctc gagttaccat
    21781 tgattgcaat tgccgcagtt ggaacgatta ttgcaattgt tatagcccaa agagatctac
    21841 aactaaaaaa tatatctgtt catgcagttc aaagcgatgc tgctgtaaat gcaacgcttg
    21901 accaagaaga ggaggatttc tttcaatgaa attagctgat ggaatttcta aagatgagaa
    21961 aaaattggtt cggaagatgt tttggcgctc gatgactatg tatgcttcgg tgaatccggt
    22021 gacgatgggc ggcggtggtt tcgcctattc tatgatgccc ttcattaatc atttctacaa
    22081 aagtgaagaa gatcgagctg cggcgctgga acgtcataca cagtattttt cgacgaccat
    22141 tccttgcgcg tcctttgtca tggggattgc ggcatcgatg gagaaggaaa attctgaaaa
    22201 agctggtttt gacgtggaaa gtatcaacgc gatcaaaacg agtttgatgg gaccattggc
    22261 tggaattggc gattcattgt tctggggagt ttggcgtgtc gttaccgcgg gactagcgat
    22321 caacttagcc aatgccggaa atattttggc accaattatc tttttagtta tgttcaatat
    22381 acctaattac ttgatgcgat actatggcgg cgttttaggc tattcattag gctctaaata
    22441 tattgaaaag ctgtatgcga acgggttaat tgaaattctg acaaaagctg ctagtatctt
    22501 gggtctgatc atggtaggtg caatgacgat cagtatggtc aaattcaata ccgttttgag
    22561 cttttcaatg aagggcgaag aactaatgaa tgtccaagaa atcctcgata gtatttttaa
    22621 aggaattgta ccgttattgg taacattgag ctgtttcaaa ttactagata aaaaagtcgg
    22681 cgtcatcaaa attatttttg gaatggtcgt cttgggaatt ttattgtcat tacttggaat
    22741 cgcatagtag gaagctgcag ctactaggct gcagtttttt tagcaaggag ggaaaagatg
    22801 actattaatg aagtaattta ttcacccaaa cacccatttt ttaatgctga gttaaacgac
    22861 ggaaatgtga ctacttcaaa cgaatacagc tactatcgga atattcctga tgtaaaggga
    22921 ttgaccttcg atgtaagtaa tcaaaagaca ttagcaaacc ttgatgtttg cgggacgatt
    22981 caaacgttga ccttttatcg agaaaattta ctaactgagg aaaaaccagg tgtttgggtc
    23041 aataaacagc tctctcaaac caattcgtta tccttaaagg ttgaagtaaa cgggattgtc
    23101 taccatttgt cagaatcgga tcatcgtatt gaagtcgatg tgattcaaga ctgtttgcct
    23161 agatatattc atcattattc gacgtttaag gtcattgtag tatcctttgc tcccatactg
    23221 gctaataagc gtttaagtat gcttgttcaa caggtttaca ttgtgaatga aacacacgaa
    23281 agccttcaag tttcagtgaa agatgtgcct tcgtatcaag agaagtattc ggatcagcaa
    23341 aatgtgttga tttctcaaaa aggaaataag gacacgatcg cacaacagga agtggcaagc
    23401 ttcgccattg cttttgtgga cccaaatgct tttgaagaag taatgacttt tcaggaatct
    23461 gatatcgaaa aatggctgaa ggaaacattg aactattttg ctcagctatt tgggcagctg
    23521 tcaatgccaa acgatagagt tgtccatctc tatcgtcgtg cactttatca aagcttttct
    23581 agtttcggta tgaatcgaca gggacaggtc gtcggcagca attggggcag ctatcctgct
    23641 actaatcgaa tttggaataa ggatatgtat tacgcatcat tgccattcac catgtttgaa
    23701 ccggagttat gtcaaaaaac ggttctatgg tttgatcaat atggcgttaa gtttcctggt
    23761 tcaaaattta caggaggtat caatcattct ctgagtaatt cgttatccag tgcgttactg
    23821 gctagtcttt attttgaaca tactggggat acaaaattct ttgagcggtg tccgcaggtt
    23881 ctactgaatg cttcaagaat tattgaggac atattagctc aacgtcggtc aggggaacca
    23941 atgctttttc catctgtttg gttatcagac gcctttgcac ttggaaagta tcataccggc
    24001 agcaatcttt gtctttggaa ggcctgtatt ggacttgcag aaatttttga agccctagaa
    24061 caactgagtc ttagcaagcg atacaaaaac attgcctgta aactaaagga atcaatttgt
    24121 aaacaaatga ctatcgatgg tccttttggt gagcaatttt tggagggaat cggtgatgag
    24181 gagaaaacaa cctattcagt gaagcactat caaaaaccga ttcttgagca agggttaatc
    24241 tttttaagtg atgtgattgt ggatggaaaa attaatttat tgatgcatga tggagaagaa
    24301 tcagacacta cgttgatgcc tttttatcaa tttttagata ataaagatca tttatatcag
    24361 aacaccatgg ccttttctgc tagttctttc aatccaacct atagcgagga aatcaaaggc
    24421 atcacttggg gattagaatc cggcgccact tttcctggct ttatcactgt tttaatgagc
    24481 gagctgcaca accctcaagc tttcgtaacc cgattagaag aactaatttg tttggcagat
    24541 ttagacggtt cgtggtggtg gtggccgtat cgcttagagg ctcaacaagg agaagtcgtg
    24601 cgagactttg gctgcggcaa atgcggctgg gcatcgggtc tttttgtcag cctaatgatc
    24661 agtcaatatt tcggattgaa attcaaaaaa ggagtattgc aaattgatcc tgttgataat
    24721 ttaacgtttt cttggaagaa tttgaagttc ggtcaagcct tcatttcgat tgaatgtacg
    24781 caatccgagt tgagtatttc aaatttgtca gaaaagccat tgaaaataag tgatacgaaa
    24841 aaaattcttc acgtagaaaa gggaaaaacg attcacattc aaaggagaaa aagatgagta
    24901 tactaaaaaa tattacccaa tttaaaaaaa tccagagtcg agcaatcact cccgaaaatc
    24961 caacaggcga gaaaggtaaa gctgcgatgt tgccaagcga gctaggacca agccgcaaag
    25021 gtcgtggcgc aattccgctg acttctggtg aagaaactgt gattgcggat attactggaa
    25081 cgggaataat tcgtcatatg tggatgacga ttcgtgatcg aacagaattt ggcagttttg
    25141 ttttacgtga tttaatctta agaatttatt gggatgggtc ggatagccct gctgttgaaa
    25201 gtcctttagg ggatttcttt tgtaatgggt ttggagagcg ttgcgaggtg aactcgttgc
    25261 cgatagtggt taatcctaca gggggcttta attcctattt cgaaatgcct ttccaaacat
    25321 ccgctaaaat tacgatcgag aatttacatc cgaaggatat gtcctcattt ttttatacga
    25381 taaattacgc tttggtggac gaattggaag aaaatagcct atattttcac gcaaattggc
    25441 atcgggaacg cattaccaaa ttacaggagg attataagtt aattgatcga ttaaagggtc
    25501 aaggctatta cgtgggtact taccttgcgc ttacctgcct agaacgttat tggtggggcg
    25561 aaggcgagtt taaattctac attgatgggg atagtgagta tccgaccgta acctcaacag
    25621 gttcagaaga ttattttggc ggggcgtggg cctttcatga gtacgatgag ttcggacgtc
    25681 cacatgcgaa aaactattca acagcctttt tagggtatcc ttaccaatca aatagagatg
    25741 ccacaagaga tcgttttgaa acgggaaaat tgaatgccgt tcatgccttt ggtgacgacg
    25801 caatgccacg acatggtctt tatcgttggc atcttcaaga ccccatctgt tttaccgaag
    25861 atttatcggt cactttacaa caaatcggca acgatgatgt tcgcttattt gagcggcaag
    25921 acgatgttgc tagtgtcgct tactggtatt caacagaagc ttcaggaaat actaaacgtc
    25981 atttcactga tcgagaacgc ttgccgcgtt aatgaagtgt ttttcacata ttcgaaggga
    26041 ggaacctatg atgatatatg gggcaattga agctggaggg actaaatttg tctgtgcagt
    26101 cggtactgag gaattaacga ttttggaaag agtcagtttt cccacaacaa ctccagttga
    26161 aacaatgaag caggtcattg atttttttaa accttttaag gaacaattgg caggcatcgg
    26221 ggtcggctgc tttggtccaa ttgatattca atgcaaatca acgagtttcg gtcatatcac
    26281 atcaacacca aaacttgctt ggcaaaattt caattttgta ggaacgctaa agcaatattt
    26341 caatattccg attgaatgga caacagatgt caatgcggct tgctatggtg aatatgttgc
    26401 tggttctggc aaagggttag caggtgttgc atacttcact gtgggaacag gtatcggagg
    26461 tggtgccttg ttcaatggga ctttcgtgga agggttcagt catccggaaa tggggcatat
    26521 gttgatcaag cgacatccaa aggacaattt ttcaggaaac tgtcccttcc accaagattg
    26581 tttagagggg atggcagcag gaccagcgat tgaaaaacgg ttgggtgtaa aaggccagaa
    26641 tttattggct gacgattcgt tttggcagat tgaagccttt taccttgccc aatgtgcata
    26701 caatacaaca ctgatgtttt cgccagatag aattattttt ggcggtggtg taatgaaaca
    26761 agaacacatg aagaaaaaag ttcaggataa atttgttgag cttataaatg gatatgttga
    26821 aataccacca attgatagct acattattac gcccgaatta ggtgataatg ccggaataat
    26881 cggcggatta gcattggcca gaaaagcggt aagaaataag caaccataat taatgaatgt
    26941 ttcattgata ctcatgtcaa aagtatttaa ccgagtaatc aaatgatcaa atgaagttgg
    27001 ataaagcgaa aatgaattca aataaaaagg ctctaagtca aatcgtgttg ttttcattaa
    27061 atcactgaaa ggaaatgctt ctgcgtttcc ttttttcttt ttgttgtgcg ctgtatacct
    27121 tgaggatatt cactggtggc gtacacttaa atagtaatat attgtgttac tttatgtctg
    27181 tggtaatagt tatagttgct taccaatgta tgttcatttt tcgaaatgtt gacttcataa
    27241 tccttggctt aatgtttgaa tttttttggt gatagatttt ttcagccgta taaaataaat
    27301 cgtaattcta ttatagagag ttgtgattat aaaaagatag caagaaaaaa aaagaaagtt
    27361 tctatacatt ttaaatattt tattcctatt tctattgcta
//
LOCUS       DARBDN010000026        27290 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000026 DARBDN010000000
VERSION     DARBDN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.026"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(226..426)
                     /locus_tag="SCH06_001157"
     CDS             complement(226..426)
                     /locus_tag="SCH06_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1077751.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(731..1963)
                     /locus_tag="SCH06_001158"
     CDS             complement(731..1963)
                     /locus_tag="SCH06_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEG1077752.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            2217..2786
                     /locus_tag="SCH06_001159"
     CDS             2217..2786
                     /locus_tag="SCH06_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1077753.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2964..3404)
                     /locus_tag="SCH06_001160"
     CDS             complement(2964..3404)
                     /locus_tag="SCH06_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEG1077754.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3562..4326
                     /gene="map"
                     /locus_tag="SCH06_001161"
     CDS             3562..4326
                     /gene="map"
                     /locus_tag="SCH06_001161"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEG1077755.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4358..5281
                     /locus_tag="SCH06_001162"
     CDS             4358..5281
                     /locus_tag="SCH06_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEG1077756.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5357..6496
                     /locus_tag="SCH06_001163"
     CDS             5357..6496
                     /locus_tag="SCH06_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEG1077757.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIVLIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6489..7289
                     /locus_tag="SCH06_001164"
     CDS             6489..7289
                     /locus_tag="SCH06_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEG1077758.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7289..8116
                     /locus_tag="SCH06_001165"
     CDS             7289..8116
                     /locus_tag="SCH06_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEG1077759.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8094..8828
                     /locus_tag="SCH06_001166"
     CDS             8094..8828
                     /locus_tag="SCH06_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1077760.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8928..9794
                     /gene="rfbA"
                     /locus_tag="SCH06_001167"
     CDS             8928..9794
                     /gene="rfbA"
                     /locus_tag="SCH06_001167"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEG1077761.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9808..10380
                     /gene="rfbC"
                     /locus_tag="SCH06_001168"
     CDS             9808..10380
                     /gene="rfbC"
                     /locus_tag="SCH06_001168"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEG1077762.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10402..11430
                     /gene="rfbB"
                     /locus_tag="SCH06_001169"
     CDS             10402..11430
                     /gene="rfbB"
                     /locus_tag="SCH06_001169"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEG1077763.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11528..12379
                     /gene="rfbD"
                     /locus_tag="SCH06_001170"
     CDS             11528..12379
                     /gene="rfbD"
                     /locus_tag="SCH06_001170"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEG1077764.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12414..14447
                     /locus_tag="SCH06_001171"
     CDS             12414..14447
                     /locus_tag="SCH06_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077765.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14491..15771
                     /locus_tag="SCH06_001172"
     CDS             14491..15771
                     /locus_tag="SCH06_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HEG1077766.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LVILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTDREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            15981..16787
                     /locus_tag="SCH06_001173"
     CDS             15981..16787
                     /locus_tag="SCH06_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077767.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16799..18019
                     /locus_tag="SCH06_001174"
     CDS             16799..18019
                     /locus_tag="SCH06_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077768.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSNGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            18009..19595
                     /locus_tag="SCH06_001175"
     CDS             18009..19595
                     /locus_tag="SCH06_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1077769.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19634..21772
                     /locus_tag="SCH06_001176"
     CDS             19634..21772
                     /locus_tag="SCH06_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1077770.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKDGIGDFSLRPD"
     gene            complement(22140..23123)
                     /locus_tag="SCH06_001177"
     CDS             complement(22140..23123)
                     /locus_tag="SCH06_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEG1077771.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            23501..24892
                     /locus_tag="SCH06_001178"
     CDS             23501..24892
                     /locus_tag="SCH06_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEG1077772.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERSFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24908..25948
                     /locus_tag="SCH06_001179"
     CDS             24908..25948
                     /locus_tag="SCH06_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1077773.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25967..27052
                     /locus_tag="SCH06_001180"
     CDS             25967..27052
                     /locus_tag="SCH06_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEG1077774.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            27085..>27290
                     /locus_tag="SCH06_001181"
     CDS             27085..>27290
                     /locus_tag="SCH06_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEG1077775.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFS"
BASE COUNT         8757 a         4541 c         5530 g         8462 t
ORIGIN      
        1 tacgaacgaa tgttcttttt gtgaaggcgg aatttaatat actgaataat agaaaacaag
       61 tacttgtgcc aaattatgtg ccaaaaaaat tcgaattcaa caaaatgtaa acaaatagaa
      121 aaccttctat attaagattt cctgcaataa caaacacaac agaagacgtg taatagttag
      181 tcaggaacgt acaaataacc cctgtatcct ttgcggtaca gggggttatt ttgtataagt
      241 agacattgta gtttctaaac tgctatgtcc taaacgtttc gatacgctaa gtatatttac
      301 tccttgataa agtaaaatag atgcatgcgt atgtcttagt ccatcaataa acagtcgaag
      361 agaaaatagg gaaaaattga ttactaaaga aaaacttact aggtcgacgg tgtagttgat
      421 tttcatactt caatagattc gaattaaacg atttcgattg gcttatacca gtcctatcca
      481 acgaaagata tatcgttctt aactctagcg gtataacttg aagctttacg taaagccaat
      541 gggaatgaac tggagatgac tttttattat ttttagtaat agctgatggg ttaatactta
      601 caactttcct tttcaaagta ccatataaaa aaacggtggg gttgtttagc gaaataaagg
      661 atctaagcca atagcttaga tcctttattc tatgctttat attatttttt gcatgtgtgc
      721 gaaagtatac tcaagcccaa tcgccatttc ggaaaatcgg tactgtagag ccatcttcac
      781 ggattccgtc gatatccatc ttgtcagatc ctaccatgaa atctacgtgg gtttgacttc
      841 tattcaatcc agcttctgct aattcttcat cggacatttc tgtaccgcct ttcacactga
      901 aggcataagc agaacctagt gctaagtgat tcgatgcgtt ttcatcaaat aatgtattga
      961 aaaagatgat gccagattga gaaataggtg aagggtcagg tacaagtgcg acttctccta
     1021 aacgacgcgc accttcatct gtatcaagca gttttgctaa gacatcttct ccttgttcgg
     1081 cagaaaaatc aacaactttt ccatctttaa aagtaaattt catacccgag atgatggtgc
     1141 cagcataact cagtggcttt gtacttgaaa tgtaaccatc tactcgatga ctgtcaggtg
     1201 ctgtgaacac ttcttccgtc ggcatatttg ccatgaattt ttctccacga gcattatagc
     1261 ttccagcgcc ttcccaaaga tggtttttag gcaatccgat aatgatatct gtaccgggag
     1321 cagtatagtg aagggcagaa aattgttctc gattcaattc ttctgctttt tttgctaatt
     1381 tttcatcatg cttcttccat gctaagacag ggtcttcttc atagacacga gtcgttttga
     1441 aaatctgatc ccataatgcc tcaacttgtt tttcttctgg cagttctggg aagacttttg
     1501 ctgcccattg tttaccagcc gcagccacga cagtccaact gactttattt gcttgagttg
     1561 ccttgcgtaa attcattagt gctttgccat tcgctgattg ataagacgct actcgatggc
     1621 tatctacacc agcaaatgca tcgggatcgg cagaaacaac gctgatcctg cttgctcctt
     1681 tttcaagcca ttcatccgct tgatcgattt tagattgtgg tacattctca atacgatccg
     1741 ttgcagcatg taaaagaaat tctctttgga tctggtcgtc agtccattga acgataacct
     1801 cagcggctcc tagtttataa gcttcttgtg tgatcaatcg agcaaggggt gcctgttcca
     1861 cgctgatctg taaaacaact gtgtgtcctt tttctgtggc tacgccagtt tctgcaatta
     1921 agcgtgcata tttttttaga agttcattaa aatcagataa cataataaaa attcctcctc
     1981 accatttttt ctggtaacta ttagcatgat accatttaat tatgattcaa acaatgaggc
     2041 tttaaataaa aaaaggaggt tattttttta aggttaagtt tcatgatata tgttactact
     2101 tgctatttca gcttgtgaag aaaatcaaaa actaattttg catatcaaaa aaacatgtta
     2161 caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta aaaaatatgg
     2221 caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa gtagctgcca
     2281 ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat tgttccacgc
     2341 aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt tttgagcaga
     2401 tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat acgattatcg
     2461 atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat cgttcactgt
     2521 acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact tactttgtga
     2581 atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc gaatctttgt
     2641 ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca agcatcatcc
     2701 atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct atcttgaaat
     2761 tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc agtaggtaac
     2821 aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca tttttaactc
     2881 ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga ataaatctgg
     2941 atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc gaaagcttct
     3001 aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc ggctcctttt
     3061 gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca gaattcatcg
     3121 taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc caattcttgc
     3181 aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta tgtataagta
     3241 gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt acattcgttg
     3301 atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc gatttcttca
     3361 gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg cctcctcgtt
     3421 tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa ataaaaccta
     3481 aagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa tgagagggat
     3541 ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat tgaaatgatg
     3601 gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt tataaaacca
     3661 ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag tcatggcgga
     3721 attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag tataaatgat
     3781 gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt ggtaaaagtc
     3841 gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta tgtagttgga
     3901 gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt gtacatcggt
     3961 attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat ccaaacttat
     4021 gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt tggtcctacg
     4081 attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt gcggttgaaa
     4141 gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa aatgaaaatg
     4201 gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca atatgaacat
     4261 acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga agaaggcact
     4321 tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga acaaaataaa
     4381 acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca ctgattcaga
     4441 aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat ttccattgat
     4501 tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg tactgaccta
     4561 tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa tcaaagacct
     4621 tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt tatggtctgc
     4681 aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg tagaaaatag
     4741 aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt tcatgattgc
     4801 tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg ctattcagcc
     4861 aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt ggccaatcac
     4921 attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta atgctcagtt
     4981 gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga tgctgttatc
     5041 acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt atcagatcat
     5101 aggaagtttt attgtactca tgctttggct taattttgct gctacgatca tcattttggg
     5161 cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca aaaaacgtcg
     5221 agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata aaaaaaagta
     5281 gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat gactcttaat
     5341 taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt ttctgacaat
     5401 tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa caggtatggt
     5461 cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg gcggactgcc
     5521 tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta tccctcaatc
     5581 gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag tgctcgatga
     5641 taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt ctcttattat
     5701 ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg gatatatcca
     5761 actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca cgaatgcggt
     5821 caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg gtttaattac
     5881 gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc cagttgttat
     5941 tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc cggcaaagat
     6001 ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc tttcactaca
     6061 agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca tgggagtgcc
     6121 ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt ctttttctac
     6181 agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc ataaaggtgc
     6241 tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg tcatgaatta
     6301 tactggaaga atcggaacga tcgtattgat tattgccatg ttgtttgctg caattttatt
     6361 atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa cattgcgatt
     6421 tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga aatggaaccg
     6481 tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg acggcaaaca
     6541 gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat gaaacagcag
     6601 taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga ctaacagagt
     6661 ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga tttggttatg
     6721 gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt aacccagata
     6781 ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa catccggaat
     6841 gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac ctcatccgtg
     6901 agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg gtcaaaaaaa
     6961 agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat gctaatagtt
     7021 atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt aaagagataa
     7081 aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt ttgagttttg
     7141 aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat ttttacggga
     7201 agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg atgaaatttt
     7261 tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag tcgttgtgct
     7321 ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag cacttagcga
     7381 aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa atgagctgtt
     7441 tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag cggtggctta
     7501 taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc tggatcagga
     7561 tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta cagatgaatg
     7621 tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc tatattcaga
     7681 tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag ctgaacgaat
     7741 catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga ttggcgggtt
     7801 taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag tggatcagtt
     7861 ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg ttttagacta
     7921 tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc gattttatca
     7981 tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa gaacagctaa
     8041 acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct catatgttaa
     8101 gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat ggaggcagat
     8161 atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat gaagtagtca
     8221 tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac gcagaaaaag
     8281 ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat tttggttatg
     8341 cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat gtttggttgg
     8401 agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag ctagtagtag
     8461 tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg tatttttcgt
     8521 ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat attggtgctg
     8581 gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca gaagtgccga
     8641 tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta agagaaccgt
     8701 taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat tctaaattac
     8761 ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga aaatggttta
     8821 aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa caattgatga
     8881 gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg aagggaatca
     8941 ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca tcgaaacaat
     9001 tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg atgttggcgg
     9061 gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc aaggaattat
     9121 ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa agtccagatg
     9181 gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt gtctgcttgg
     9241 tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa cgagcagctt
     9301 caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa cgctttggtg
     9361 tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct gctcagccaa
     9421 aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt tctatcgcta
     9481 aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat aaagcatatt
     9541 tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg cttgatacag
     9601 gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa aaacgtcaga
     9661 acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc gataaggaac
     9721 aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat ttattgaatt
     9781 tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt aacagatgtc
     9841 aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga aagttattca
     9901 aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa ccattcacta
     9961 tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc tgcacagaca
    10021 aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat ccgcaaaggt
    10081 agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca tcgacagttg
    10141 cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt gaacttcctt
    10201 tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt tgatgatcca
    10261 gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga aaaagatcac
    10321 cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg agaaatctaa
    10381 gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc cggattcatc
    10441 ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt cactgttttg
    10501 gataaactga cttatgcagg aaacaaagag aacttggccg gacttcctag cgatcgcgta
    10561 gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt aaaagaagcg
    10621 gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa agatcctttc
    10681 ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg ccgcaagtat
    10741 gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc attacgtgaa
    10801 gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac accatataat
    10861 ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa agcatgggtg
    10921 cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg tccttatcag
    10981 catattgaaa aatttattcc tcgccaagta acgagtatct taagcggtat tcgtccaaaa
    11041 ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca ttcttcagca
    11101 gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg tgcagacggt
    11161 gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggcca accaaaagac
    11221 gcatacgacc atgtaaacga ccgcgcaggg cacgatttgc gttatgcaat cgattcgaca
    11281 aaattgcgag aagagctagg ttggcagcct gagtttacga acttccgtga tgggttggct
    11341 gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa agaggccgtt
    11401 gaagcagcat atgccaaaaa tggacaataa tacagaggaa atttcactgt attaatggaa
    11461 aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc aaggagcgga
    11521 taaccatatg tttttattaa ctggaggaaa tggacaatta ggtacagaat tgcgccattt
    11581 attagatgaa aaaaatctgc catatgtttc aacagatgca aaagacttgg atatcacaga
    11641 tgctgagaaa acaatggctt atattacaga attaaaaccc gatgttattt tccattgcgc
    11701 agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg agaaaatcaa
    11761 tgtcgatggc acaagaaatg tagcacttgc agcaaaagct gtgaatgcac aattcgtcta
    11821 tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg aagtagacga
    11881 ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga
    11941 agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga tctatggaca
    12001 caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa
    12061 tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg tatatgtcat
    12121 cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct gttcttggta
    12181 tgagttcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg ttacgtcaga
    12241 agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga aaaagacaga
    12301 agcgttaggt tttgtcatac caacttggca agaagcactt gcgcaaatgc tggaagctgc
    12361 caaaaaaatg aataagtaat ttccttttta tcaaatagaa tttggagcat gatatggaaa
    12421 aacaaacaag aagtgcacga cgaaaagaaa agccaaaagc gaatcaggca gattcgaatt
    12481 tggtgcttga cctgtttcta aaactccgct atcttattgg cgttttagtc atcgtggtca
    12541 tcgttacttt taatttaaac ggaagttcac ttggtgtttg ggataaatat gtgtcgcaaa
    12601 gagacgatgg gaaaaaaact gatgtgattt ttggacagaa tcgggaagtg cggtcagacg
    12661 aatggctggt gcagacacct ttttacctct cacaagctga agaggacttt tcgttggtga
    12721 acgaggatta ttcattaaac ggacaaaaca tgatcattgc gtataattct cctgtaaagg
    12781 atattacggt tatcggaaaa ccattcaact ggggattctt tttcctcgga agagatcgag
    12841 gactttcctt ttattgggcg atgaaattag tcgtcatggt cttgcttgga ttcgaagtac
    12901 tgatgatatt aacgaagagg aaaaaagctc tatcgctaat cggtgcattt gcgctgacat
    12961 tttctccagc agtccagtgg tggttcatgc aacatgtggg cgatttgatt ttctttactt
    13021 tgggactgat gattgctttt tatcattatt tctacaatca tgataaaaaa tggctacgaa
    13081 cgttgatgat gcttttggtg gttattttcg gtattgggtt tattttagtg atttacccag
    13141 cccatcaagt gatgctggcg tacttgctga ttttttattt tgttggcctg cttatttact
    13201 atagcaagaa agtttcatgg gatctgttgg atgtagtgtt gattggaggg gcagttttat
    13261 ttattggcgg agtcatggtt catttctggc taacgtcaaa agacgcattg ttagcttctt
    13321 tgaatacctt atatccagga aaacgggtaa gtactggagg aaagtggacg attggcgaat
    13381 ttttttcttt ccttacaaat tggaaaattc cttttgaaga tatcaactat tcgaataact
    13441 ctgaagtggc cctgttctat cacttttttc caactgtatt cctagcaagt ccatttgtgt
    13501 tatttggcaa aaaagatagc gaacaaaagt tactgggacg tattttgatg attttttgtc
    13561 tgttttctat cttttggatt accgttgggt tgccaaaatg gctagcagaa atcactctgc
    13621 tgtcttatgt tcctccatta agagccatcc ttacttttag ttttgcggct tgtttattat
    13681 cgatctggtt tatcgcttat atttggagag aagatgttat tcctatttgg tataaattca
    13741 ttttgttggc agtaaatgca tggtcttatt tctatgcgat tacgcattcg aaaatggata
    13801 attatttttc ggattttgaa accatcgcag ttgctgtgtt gggaacagtg attttagctt
    13861 ttgcattatt tggctggaga cgcttgtttt acctcgcttt tgtcgcctta gttatcgtat
    13921 ctggcttttt cgtcaatcca gtcgtagaag gtacaggagc gatttttgaa aaaacactgg
    13981 caaaagaaat ccaaaaaatc gatcaacaag atcctggtaa agtttggttg tctgaagatg
    14041 aattatataa cttcacccca acattgggag tgaaatcctt caatacagta cgcttttatc
    14101 cagatatagc tgcatggaag aaaatcgatc cgaaagaaga atacgagaag tattataatc
    14161 ggtatgctca tacaagagct tttatcgcta aggaagatac aaagttcatt ttagatcgtc
    14221 cagatatgtt ttcggtcacg ttgaattttg aagacgcaga aaaattaggg atcgactatg
    14281 tgatcagtaa acgaccatta actgattaca accaattata tgaagcgcag ttcacgcagc
    14341 tatatggacc ggataaagac ggttatatga tttttaaagt agaatatccg gattatccag
    14401 atgtaccaca aacacaaact caggaaaatc agctagtcgt acagtaatag gctagctgag
    14461 aataatcctg aaatattagt agaaaggaga gtgaagataa ttcaagcaat cgtacaaaaa
    14521 tttgtcaaca aaatgagtgt cggtttcttg cttttgttgc tgacgctagt cttttttgtt
    14581 tggacagcag gggtaggttt tccagcaact ttgtttatat ataacaatag ttcattactt
    14641 atcgctttta gtgtggctat tttgctcatt ttaaatgttt ataaagcaaa aggcgtcgat
    14701 tttctttatc taggtgttgc gcttgccctt ttcattttct tttcttactt tcgggaatta
    14761 agaaatgagt ctttatttgg agacttactg tttcctttgg ttattttatt ttgtttagta
    14821 attaaatgga tcgagtggac aaaatgggat cgcggtattt atctgattgt ctttacggtc
    14881 ttcctcggaa tcacgttata tcgtgtattt acagagatcc aagtaccaga aggacaaagc
    14941 atctgggctc caggcaattc gctttctgat atttggatca atacgaatac aatcggaagt
    15001 tctttgatga ctcttgcttt attgatcagt ggatttgcca gttcttttga acgatggtat
    15061 gttcgaatca tcggtgggat agcagtcgtt gcagcctttt taggtatttg ggtctgccaa
    15121 tctagaggtg cattagtcgc gttgattgtt tttgcgatat tggatctttt acctaaatcg
    15181 ttgatgcgtg tcattcgtgc gccatttatt gcctacacgg ttacgattct tttagctttg
    15241 ccgatttctt atctggcggc tgtctctgaa aaagtcaatt tgtttaccga tcgagaagat
    15301 atttggcata aattctatca gacgctagga gaaaaatctg aacaagtttt actaggaatg
    15361 aaaacattta tcttccagcg aggaaaccaa tttttaggaa accacaatag ttataattct
    15421 attttgaata tctatggatt gataggattt gggattgctg ctttgctgct tatccttttt
    15481 attggtcgct taacgttgaa agcagattta tccaacgggc agatgacttt tatctgggcc
    15541 ttttttgcgg tgatgatgca gtcatttatg gaggatacat tgacttcata cccatgggtt
    15601 ccgattattt atatcctgtt ggctatggcc gttcatcgat atgatgaacc agaagttgcg
    15661 gaggaattct atgttatgga agaggcatat gacgatatga cttatgatga tacatcttat
    15721 gaggaacaac cagatagcgc tcattcttcc aggatccaac gctatcattg ataggcacaa
    15781 aatacgagag aggctgtgac aaccgtcgca gccttttttg gtttattgca attgtctagc
    15841 atcttctgta aaatagaaac gttagagaaa atcttgtatc atagaaaatt aagaaagaaa
    15901 taagaacgca gctcggtacc aaaaatatgg taaaatggca cttgactgta attcactgaa
    15961 aatcgcttgg aggaacacaa atgtttaaag atttgtattt atttatgaag gacatttatc
    16021 agaacagaaa attattgcta cagttttcga tcaatgactt caaatcaaga tatgcaggat
    16081 cgtttttagg aatcttatgg gcgtttatca atccgctatt tactgtattg atttattggc
    16141 tggtatttgg tgttggactg aaagcacaaa tgatcgatgc aaaataccca tttatcgtat
    16201 atttagttac cgggatgatt ccctggttct tcttctcaga tgcatttgca tcaactacgg
    16261 ttgtttttcg ggaatatact tatttagtaa agaaagtcgt attcaatatt cgtatcttgc
    16321 ccacgacgaa aatcctatcc aatctgtaca cccatttatt cttcattctg attggcatag
    16381 ctgtcgcgct tataaatggt atatatcctt cagcaatgtc tttacagctg atttattatt
    16441 tattttgcat gtgtgctttc ttgacaggat tgacttggct gacggcatcg atccaaccat
    16501 ttttacctga tatcatgcaa ttaattacga tcgtgctgca gttgatcatg tggacattac
    16561 cgatattatg gagccctaat cagtttgatt caggtcttgt aagcatattg aaattaaatc
    16621 cgctgtacta tgttgttcaa ggttatcgtg agtcattttt aagtgaagct tggttctggg
    16681 agcatggaac atatactttg tatttctggg ttttcacgtt agtaatgttc gtaatcggct
    16741 ctgcagtgtt ccgtagattg aaaccacatt tttcagatgt gctgtaagga gaatagctat
    16801 gacagaatat gcaattagac taaaagatat cacaaaatct tataatatgt acgcaaaacc
    16861 ttcggatcga tttcgtgaag ccctcaatcc ttttaagaaa tcctatcatg atgtatttta
    16921 tgcgttgaaa aacgtgaatg tagaaataaa aaaaggtgag atgatcggtt tcgtgggaga
    16981 aaacggatcg ggaaaatcta caatgttgaa aatcattacg ggagtactga caccaacatc
    17041 cggcacgatg gaaatcgaag gaaaaatctc agctttgcta gaactaggat caggattcaa
    17101 tcctgagtat tctggctatg aaaatatcta tttaaatgga atggttctag gattttcaag
    17161 agaagaagtc gatgaaatgg tcgatgatat cattgaattt gctgacatcg gagaccatat
    17221 ttatcaacct gtaaaaactt attcaaacgg gatgttcgtt cgtctagctt ttgctgtagc
    17281 aatcaatgtg aatcccgata ttttgattgt ggatgaagca ttggcagtag gcgatcttga
    17341 atttcaacta aaatgtatgg aaaaatttac agaaatcaag aactcgggaa agacgatttt
    17401 attcgtttct catgatatca gttcgattcg tcgtttttgt gatcgttcct attggttgaa
    17461 aaacggagaa gtcgtcgaat atggcgatac gatggaagta acgacgaatt atgaaaactt
    17521 tttaaagaaa aaatcagtta aaacagtgga tcggaataaa aaccaagtag aacggttcgc
    17581 cgctccagat atcgtcgacg tgacgaaagc ggaattgttg gataaagaca aaaatccggt
    17641 ggatatgctg gaacaaggag aaaaactata cgttaaagta acttatgaag taaaagatga
    17701 tacaatcaaa aatccggttt taggaattgc gctacgaaca gtcgacaatt tttatgtatg
    17761 cggacttaat actctactag atggtatcaa gattccttgg aaaaaaggag agaatatctt
    17821 ttatctggag tatgaaaagt taggtttgtt agctggtgaa tattattttg acgttgcggt
    17881 ctttgaagaa aatgcaacgg ttcctttggt atataagaca aagtacatga acttgtttgt
    17941 cagcggttct tatatcggag aaggcatcgt ggtcttagac cataaatggg aagaagggac
    18001 tcatagcaat gaaatatgat tttgaaatgg acctagatga acaaagcagt gtgggaaaaa
    18061 ttgccgcaca gatcaaacca ggaagtaaag ttttagagtt tggtcccgga aacggccgat
    18121 taacgaaaca tttaatcgga gcaaaacaat gtgaagtgag cattgttgag ttagataagg
    18181 aattgttcga ttttgtcagc gaatttgctc aagatggatt ttatggtgat atcgaaagtt
    18241 ttgagtgggc aaactattat gctggacaga catttgatta cgtcttgttt gcggatgttt
    18301 tagaacattt ggtagatcct ggaaaaacat tgaagaaagt cagagaattt ttgaatgaag
    18361 aaggagagat cctgattaca ttccctaact tggcgcataa ttctgtcatg atcgatttgt
    18421 tcaataacca attgccgtgg gcttcttatg gtctcctaga tgaaacccat aattcttttt
    18481 atactcatga tggcttccaa aaagtttttg aaaaagcggg attattcatt aatattgaag
    18541 attatttgta cttagctgta ggtgatacag aattaaaatc aacttatgaa gaattgccgg
    18601 aagctgtacg ctatgatttc aaaatgcgac catttggtga agtctaccaa tactttttct
    18661 cattgatgaa acatccagta gcacaaagtt ccattgcaga gccacaaaat tctaattatg
    18721 taaaagtgtt agaagtaacc cagcaaacga aacaagatga aacaatccaa caaataccat
    18781 tcaataattt cacaggggaa aatgagacac taagtttccc cgtatcagaa acaacagaaa
    18841 gaatggtgtt tcgcttcgcg caacaaccta gctttatcga attcagcgca gaagctgccg
    18901 gagaaaaact aacatttatc gattcgaatg ctgtagtcaa aacagtaaat gattgttatt
    18961 tgtttgatgg gaaagaatta ccagagttcg ttctaacgga tatttctggg aaagaagtga
    19021 ctatccattg tcactatcgc tttatcgggg aattgacacc aacaatgaaa gaattgttgg
    19081 aaacgattcg tcccatggct gaagtcacaa agcagctttc tgagaaaaat gacgaattag
    19141 aaagagaaaa tcatcatctt cttgaggaaa atacaagact agaccatacg ttaaaaacaa
    19201 ccacaaatcg ctattgcaca ttgttggaaa gtgatgaatg gacaataaaa catagactag
    19261 gacgacgtaa gaaagaaact tcgaaaaaaa tccaagaaaa agaactttct atatgtattg
    19321 acgagaaaat ctgggatgca gaaacaaaaa tattaaaaat catcggatgg ggaatcgcta
    19381 attcggatcg ccagcccttg tcctataagt tatcagctga ccaatcgcca tttttcgaag
    19441 caattcctgt ttcacgagaa gaagtcaatc aagcagaaca gctcgcaaaa ggaacagaag
    19501 cgggatttga gttacgaatc ctttgcgagc aagaacgttc attcttagtg gaagcagtag
    19561 ctcaaaatgg ccaatcatgg atcattgaaa tgtaaataat gattaactta taaagataag
    19621 gagtaaacga atcgtgcaaa aaaaagaaat tgccgtattt atcgatcaaa tcactcgtga
    19681 acgggccact ggcgatttgc ttattgtggg ctgggcaatt gatgaagtga ccaaagaaat
    19741 ccctacgata aaggtagaaa aagaaaatgt gattgctgaa gcaacacatg tcgtaagatt
    19801 ggatatcaat catttatata atcttgatgt taagacccaa agcggtttca aggtacgttt
    19861 atcagggaaa atgagaggaa aagccatctt agacttccaa acagcgagac atcaaaatgg
    19921 catagctgtg aaattaaacg gtaaataccc ttatgatgac ggcattgaat cttcatggga
    19981 aagaaaaaaa agattactga aaaaagggat aaattatgca aggactcatg gcgtaaaaaa
    20041 agcgatccgt cgggtcaaat tggaattgaa gccaggatcg atcgactatg cagagtggat
    20101 cagtcgtcat gagaaaccag atttgaaaga gcaaaggaaa gaagcacaag gatttgcgta
    20161 ccgtccattg atttccatac ttatgcctgt ctataacgtt gaaatcaaat ggctcgaaaa
    20221 atgcattgat tcggtactgg atcaaacgta tgatcattgg gaactatgta tcagtgatga
    20281 tgcttctact gatccagcta tccgaaagtg tctggaatcc tatcaagcaa aagatgatag
    20341 aatcaaagtc gttttccgaa aagaaaatgg acacatcagt ctggcaacta attctgcatt
    20401 ggaaatagca gaaggagaat ttatagcact cttagataat gatgatgaat taccgccatt
    20461 tgcattatat gaagtggcaa aagtgctaaa cgtacatcca gaactggatg tgatctacag
    20521 tgacgaagat aaaatcgatg cagatggcaa tcgctttgat ccgcatttca aagcagactg
    20581 gtcgcctgat acattgatgg gaaataatta tatctctcac ttaggcgtat atcgaacaag
    20641 cattgttaaa gaacttggcg gtttccgtaa aggctatgaa ggttctcaag attatgattt
    20701 ggtccttcgt gtgacagaac aaatccctgc agatcatatt taccacattg accgagtctt
    20761 gtatcattgg cggacgatcc caggatcaac tgcaagtaat ggcgaagcca aaagttatat
    20821 ctatgattcc ggagtgaaag cattgacaga tgccctgtct agaagaaaca tcaaaggaag
    20881 cgtacgtcct ggcagaattt ctggatttta tgagattgct tatgacgtct tgcaagagga
    20941 tttggtcagt gtgatcattc caacgaagaa tggctatgaa gatctaaaaa cttgtgtgga
    21001 ttcgatcatc gaaaaaacgt cttattcaaa ttatgaaatc attattgcgg ataacggaag
    21061 tacagatcca aaaatgcaag aattatttgc agaatacaag catcagctga aagaccgctt
    21121 tatcgtagaa ttgattgaca ttccattcaa ttattctcga attaacaatt tagcagcaga
    21181 aaaagcaaac ggcaaatact ttttattctt gaataacgat acagaagtga ttgagccaga
    21241 ttggatgacg gtgatggttt cttatgcaca gtttgatcga atcggctgtg taggagcaaa
    21301 actgttttat ccagatgata caacgcagca tgcaggagta ttattaggaa tcggtggtgt
    21361 tgcagggcat gcattgaata actatgatcg aacacattgt ggttatttcg gccgattggt
    21421 cattgacgtc aattacttag cagtcactgc agcttgtatg atggtcaagg cagctgactt
    21481 caatgctgtt aacgggtttg atgaaacatt agaagtagca ttcaacgatg ttgacttgtg
    21541 cttgaaagtt tatgaactgg gtcgttacaa tgtctatgca catcaagcag aattgtacca
    21601 tttcgaatct aaatcaagag gttatgaaga tactccagaa aaacaaagac gttttgctgg
    21661 tgaaatcaaa aaaatgcaag ataaatggcc agcatatatt gcgcatgatc cattttacaa
    21721 tgataattta acaaaagacg gaatcggcga cttttcgttg agaccagatt aaactataat
    21781 aaaaagctgt tatgttgtga ttcgctcgca cataacggct ttttatagtt ttttgtcaaa
    21841 aaaaggcaga aggtgccgac tcaaaaaaat aagtcgaggt tgggacagaa gtgtttaact
    21901 ccgagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcggctta
    21961 tttaagaaga agttgcttct gctcccaccg tttattcgtt tttaaagaat gagacaaaag
    22021 tgtttcttac ttttgtccca cgctcttatt catgctcaga gcgccaatag atacaaaatc
    22081 atagccaaag tttcacgaac cctagctgtc aaagaatcga tattttattt taatataggc
    22141 tattttaaaa taaatggttt aaggtattcc tctacaaaag ccactctatc aattatcatg
    22201 ggtttaaaat aagaagtgat ggagataacc agattgttct tagcgtcaat ataaagaaca
    22261 tttccactat taccaattgc tgaatatatt tcgttctcag aatctaatac ccaccataaa
    22321 tagccatatc tcatattttg taagtcttct aaagcactgg ttctaggttt gaacatctcg
    22381 tttatccaca tgggtggtac gatttgtttt cctttataca tccctttatt taggcataat
    22441 acaccaattt ttgccagatc acttgccgat aaacacaaac catatcctgc cgtcccgata
    22501 tttagtggat cacaaaacca gacattggtt ttaggagact tatccattgt aaactgctta
    22561 tgttcttcag ctgtttcagc ataataattg acatggtttg gtatccctat aggatcaaat
    22621 agatacttat tggcaaaatc aacagttgtt agcttacttg tctgatacaa caagccagtt
    22681 aatatgtgta aacagacagt ttgatagttg aattcgccgg ttataccttt tcttcctccc
    22741 aataaatcta gtgatgtttt tgtccaatct tcacttgaac agacttttgt ccatggatcg
    22801 cctttacatt tgtagggtgc tttcattgtt agcaagtgct tgattgtaat agcgtaaata
    22861 gttttctccc cgcgtttcac tttatactct ggaaaataat ctaatacttt atcatcgata
    22921 cttttgatta atccttgctc taaagcaatg ccaatcagca aagatacaat acttttcgtt
    22981 gctgacatga tatgacaagt atcgtctttt ttataaccat tccattcatc tgtataaact
    23041 tctaccccat ccttatatgc gacaatttga catatatttg gttgtcgaaa accaataaaa
    23101 tcatgcaact cttgtttatt cataagatat tacctcactt tcttctataa gcataatgtc
    23161 attaaaaatc gatttcaatt ttttcgattc ttcacgtaat acaggtattc ttatggacta
    23221 gacagcgctt tgggaagatg gattctctga aaaatataaa ggttcacttt atgagtggat
    23281 aaaaaaagca gcaaatactt cgacttcttt aatttaccaa cattagtgaa aatcgattca
    23341 tctggagatt tgtaatttag agtccttgtc ttgattagag gtgtataaag ctttttatta
    23401 gacattttta aattccatta caatttgctt ataaactagg tttttaaagg tgactatggt
    23461 aagataatag agatattatt ttgtgattag gagtgtatat atgaataaaa atggagaatg
    23521 gagtgctgca cgacggatat tcattatatt aatggatgtt attgtataca atgcagcaat
    23581 atatagtagt ttcttactga agtttcgtgg agagatccca ttacgaaatt tagaaacttt
    23641 ccaacactca gcaattatta tttcagtgat ttttattgcg ttgaacattt tgttgggtgc
    23701 atatgttttt tataatcgaa tgatcagtga catcgtgttt gtcacagtca tcggtcaggt
    23761 attgatgaca ctagggatca tggtagtgac ttttgcgggc cgctggtttg cttttccacg
    23821 tcttgttatc ttactttcat ttgttctcgg tacgcttttc ttaagtatct atcgtattct
    23881 cgtatataaa ctttatttac gcgtaagtcg agataaaaag gtcgtcatta ttgggttaga
    23941 aaaggatgtc gcaccagcaa tccaaaattt tggttcaaag aaaaacaaca aacataaagt
    24001 cgaagcagtc attcttgata actattatgc aaacatcaaa aatatgatta aagacatcga
    24061 tattgtctat cttgcttctc atatcgaaga aactgaaaaa atcaaaatct atcaattagt
    24121 tactaaaaat gaaaaaaaat tgtttttgaa tacaacattt gaaaacttga cattgatcaa
    24181 tccaaatatt atgaatttcg aagatgaaag tattattgaa gcatctggat ttagaatcca
    24241 acctgaatat gaactattca aacgtttgtt tgatatcatc gtttcacttg ttttattagt
    24301 tattgcttca ccatttatgt tattcacagc aattttagtc aaagtgacat caccgggacc
    24361 aatcatctat aaacaagtgc ggatcacaaa aaatcaaaag gaattttcaa tctataaatt
    24421 ccgctcgatg accgccacag ccgaagcaaa atctggacca gttttagcta agagcaatga
    24481 tgcacgagta acgcctgtag gtaaatttat tcgagctgtc cgctttgatg aattaccaca
    24541 aatcttcaat gtgctgaaag gcgatatgtc gatcgtagga ccacgtcctg aacgttcttt
    24601 cttcgtcgat cagttcaatg cagaaaaccc ttattactac ttacggcata atgttcgtgc
    24661 tggtatcact gggtatgcac aagtctatgg aaaatatgtc tctgattaca acagtaaatt
    24721 acgttttgat ttactttata tcaaaaaata ttcattgatg cttgatttaa agatcttgct
    24781 gcaaaccatc aagatcctat ttgataaaat gtcctctcaa ggacttgaag aagacgaaaa
    24841 tgtgatctca ttggcagaaa ttgcttttcc gaatgaaaaa atctttcgct agttgggagg
    24901 cgtaaaaatg aacaatccga aattcagcat aatcgtacca gtatacaatg cagaagcaac
    24961 tattggtcga acgattgata ttctaaaaga attggattat gaagagtacg aagtcgtttt
    25021 agtaaatgat ggatcaacag atcaaacaca ggaaatcatt caagaactga ttgaaaatga
    25081 tgaacgtttt gaattgatta ctacgaccaa tcaagggccc ggattagcaa gaaacgaagg
    25141 aataagacag tcaaaaggag aatatctctt attcttcgat gcagatgaca cgccagtaaa
    25201 aacgatcttg tcagattatg atcatttgct agaaaagagt ccaaaagcgg atcttgttgt
    25261 tagttcgttt gtttttcgta caatggacga gggaagaatc gtttccgaaa aagaaaactt
    25321 agttacagaa tgtcactatc taactcacga agagtttata aaagacatgt atcagttaat
    25381 gaatgaacag ttgatgtatg ttgtatggaa caaatgctat cgtagcgata ttctgaaaaa
    25441 taaccaaatt ctatttaaaa cttataatag ttgtgaggat cgaatattta acttacatta
    25501 ttatgaatac tgtcatcaag tgatcatgaa cccaaaagta gaatatattt atgaatttga
    25561 aggtgggaag gggatcacta atcaataccg acctaacaag ttcgaaacat ttaaagaatt
    25621 ctattcatta gcaaatactg taacagacga tattaataaa gacggtatgg cggcgcttct
    25681 tttaaaaggg acaacttcag ttattttttc tatttatagt acctctgcaa gaacttcaaa
    25741 agagaagaaa gacgaagcaa agcagatatt gagtgatcca gtgatccgag aagccaagca
    25801 aattgctaag acggattctt cagcaaaaaa aataacaaag ttgctttaca atatgccagc
    25861 tccactattt ttatctgctg taaaagttgg aagcttcgtt gaagtgaaaa tgccagggtt
    25921 aatggctgct ttgaagcgag tatattagtt aatggaggaa aatataatga aaagaatttt
    25981 gcattttcag ggacgaatgg gtttaggtgg agcagagtct ttcatgatga atttatatcg
    26041 taaaattgat cgtacaaact atcaatttga ttttttgatt tatgaagatt atgcagatgt
    26101 tcaagactat cattcagaga ttgaaagatt aggaggccgt atttttgttg tacctaatcc
    26161 taagaaaaat atttttaaat atttaataga agtgaataag ttactaaaaa aagaatcttt
    26221 ttctatagtt cacaatcagg tttattttgg cgggggaatt aatttatggt tagccaaaaa
    26281 gaatggaatc agacagagaa ttgctcatag ccatgcaact gaagatggaa aatctcaaaa
    26341 tattgtaatg aatgtattgc gtaaattttt aaccaaattg ttgttacaaa atgcaacaga
    26401 ctaccttgcc gttagtcaag aagctggtga aagtctgttt caaaaccatc cctttgagat
    26461 agttcataat ggtattgatt tagagcttta tagtaaaaat tcagaagcta aggttaataa
    26521 gagaaaagaa ttggatatct caatgagtac ttttgttgtg ggaaacattg gacgattaga
    26581 gaaacaaaaa aatcaatctt atttgttaga gattttttta gaaatactaa aaatgaattc
    26641 tgattcttac ttgattttag taggtgaagg gtcacttaga aataaactga aagccaaagc
    26701 agtagaattg gatatagaga aaagagtaaa atttttagga gaaagaaacg atattcccga
    26761 gttattatct gtgatggatg tttttgtaat gccttctctt tatgaaggtc tgccaatggt
    26821 tggattagaa gcacaagcag caaaattaaa attagtctta gcagatacta tttccaaaga
    26881 tacaaagtta acaaataatg tggattttgt atcattagat gaaacaccac aagaatgggc
    26941 aaaaaaagta ataaaagagc cgtatgctaa taaaataaca caagaactaa agagttatga
    27001 tgtttcgtac actactgaac aaatggagag tatatatagt agagatcatt aaaaatgttc
    27061 aagatatttt aggagtgatt atttttgaaa atatgttatt tgatattggc atacaatgat
    27121 attggcaact taaagagatt ggtcaatcga ttgaacgaaa atgcagtttt tattattcat
    27181 atagataaaa aaactgatat agaaccattt attgaagcat ttaaatcata tgataatgtt
    27241 gaatttttat gtaataaaaa ccgtgttaaa atttattggg gtggtttttc
//
LOCUS       DARBDN010000027        25761 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000027 DARBDN010000000
VERSION     DARBDN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.027"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            22..504
                     /locus_tag="SCH06_001182"
     CDS             22..504
                     /locus_tag="SCH06_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HEG1077776.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            541..1551
                     /locus_tag="SCH06_001183"
     CDS             541..1551
                     /locus_tag="SCH06_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEG1077777.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(1666..2379)
                     /locus_tag="SCH06_001184"
     CDS             complement(1666..2379)
                     /locus_tag="SCH06_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077778.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(2569..3159)
                     /locus_tag="SCH06_001185"
     CDS             complement(2569..3159)
                     /locus_tag="SCH06_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HEG1077779.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            3643..3870
                     /locus_tag="SCH06_001186"
     CDS             3643..3870
                     /locus_tag="SCH06_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEG1077780.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            3886..5052
                     /locus_tag="SCH06_001187"
     CDS             3886..5052
                     /locus_tag="SCH06_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEG1077781.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            5286..6329
                     /gene="hrcA"
                     /locus_tag="SCH06_001188"
     CDS             5286..6329
                     /gene="hrcA"
                     /locus_tag="SCH06_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEG1077782.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            6423..6986
                     /gene="grpE"
                     /locus_tag="SCH06_001189"
     CDS             6423..6986
                     /gene="grpE"
                     /locus_tag="SCH06_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEG1077783.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            7037..8866
                     /gene="dnaK"
                     /locus_tag="SCH06_001190"
     CDS             7037..8866
                     /gene="dnaK"
                     /locus_tag="SCH06_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEG1077784.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            9017..10183
                     /gene="dnaJ"
                     /locus_tag="SCH06_001191"
     CDS             9017..10183
                     /gene="dnaJ"
                     /locus_tag="SCH06_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEG1077785.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(10265..10930)
                     /locus_tag="SCH06_001192"
     CDS             complement(10265..10930)
                     /locus_tag="SCH06_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077786.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            10906..11079
                     /locus_tag="SCH06_001193"
     CDS             10906..11079
                     /locus_tag="SCH06_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077787.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(11124..11861)
                     /locus_tag="SCH06_001194"
     CDS             complement(11124..11861)
                     /locus_tag="SCH06_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEG1077788.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(11863..13365)
                     /locus_tag="SCH06_001195"
     CDS             complement(11863..13365)
                     /locus_tag="SCH06_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEG1077789.1"
                     /translation="MKRKHLFHSFVFLMTGLVTFAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13624..15618
                     /gene="uvrB"
                     /locus_tag="SCH06_001196"
     CDS             13624..15618
                     /gene="uvrB"
                     /locus_tag="SCH06_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HEG1077790.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            15628..18444
                     /gene="uvrA"
                     /locus_tag="SCH06_001197"
     CDS             15628..18444
                     /gene="uvrA"
                     /locus_tag="SCH06_001197"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEG1077791.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            18707..19972
                     /locus_tag="SCH06_001198"
     CDS             18707..19972
                     /locus_tag="SCH06_001198"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HEG1077792.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            19976..20707
                     /locus_tag="SCH06_001199"
     CDS             19976..20707
                     /locus_tag="SCH06_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HEG1077793.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            20842..21726
                     /gene="rapZ"
                     /locus_tag="SCH06_001200"
     CDS             20842..21726
                     /gene="rapZ"
                     /locus_tag="SCH06_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEG1077794.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            21723..22721
                     /locus_tag="SCH06_001201"
     CDS             21723..22721
                     /locus_tag="SCH06_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEG1077795.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            22755..23690
                     /gene="whiA"
                     /locus_tag="SCH06_001202"
     CDS             22755..23690
                     /gene="whiA"
                     /locus_tag="SCH06_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEG1077796.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            24233..24883
                     /locus_tag="SCH06_001203"
     CDS             24233..24883
                     /locus_tag="SCH06_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077797.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            25070..25651
                     /locus_tag="SCH06_001204"
     CDS             25070..25651
                     /locus_tag="SCH06_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HEG1077798.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFIDYYLSN"
     gene            complement(25648..>25761)
                     /locus_tag="SCH06_001205"
     CDS             complement(25648..>25761)
                     /locus_tag="SCH06_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1077799.1"
                     /translation="FISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         8505 a         4355 c         5506 g         7395 t
ORIGIN      
        1 aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca cgaaaatata
       61 tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt ggtaataaag
      121 aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga taaaaaagat
      181 aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc attagggaag
      241 atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca aacgggacaa
      301 aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat tattgatgaa
      361 gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca aacgatggtc
      421 atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat atttttgatg
      481 ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag gtgaagcaac
      541 atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc accatcctca
      601 ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat ggaagaaaaa
      661 tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa atcaggtcca
      721 gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat ccaaatgatc
      781 tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga ttttgatgct
      841 ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact tgctgtcaca
      901 ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag aggagagtac
      961 ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg agaatcgatt
     1021 ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc atcatcttct
     1081 gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc agtaaggatg
     1141 aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg tactccttat
     1201 ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt gtggtttcta
     1261 gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat gaaactggca
     1321 ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga ggatttgtta
     1381 gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact accgatcttg
     1441 tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg tgcctatgca
     1501 gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta aaaaattttt
     1561 tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag tgaaagaagc
     1621 tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat tatctataac
     1681 tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag ctactacaga
     1741 tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag atgtttgatc
     1801 tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt catggttact
     1861 tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca catctttcgg
     1921 atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat aatgaataac
     1981 atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag ctagccaaac
     2041 acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg actgagaaga
     2101 ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg tactactaga
     2161 tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat tcgtttcagt
     2221 agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga ttgaactttt
     2281 gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc ctacaaggaa
     2341 taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct cattattttt
     2401 ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt ctatgaatat
     2461 aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa tcatcagtaa
     2521 aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt aggagaaagg
     2581 atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa tcgttttttc
     2641 tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga attctatagg
     2701 agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt ctataaaatc
     2761 ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc cggtgtgttt
     2821 gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa tagcagctac
     2881 tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat tttttatgtc
     2941 ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt gttcgattaa
     3001 gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga tagaagcagt
     3061 tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac cttcccaatc
     3121 ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct cctttactat
     3181 ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt agcgacagcg
     3241 aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa ttaaatacga
     3301 actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat tttgcataca
     3361 tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga aactggaagg
     3421 caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca tgaaaacaac
     3481 cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc aagaagtcga
     3541 ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta tatgagaggt
     3601 tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat agcttttcat
     3661 atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt ttatcgagag
     3721 gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga gctaggtttc
     3781 cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga ttttaagaag
     3841 gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat agaaacaata
     3901 aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga gcatatctgc
     3961 tattactgtg attttaataa agttttttta gaagggcagc cagtagatga gtatgtggaa
     4021 atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa tttagaaaca
     4081 ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga tcgactgtta
     4141 tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt agaagcgaat
     4201 ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt caatcgttta
     4261 tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg taaacacacc
     4321 gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac caatgtaagc
     4381 atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga tactttggaa
     4441 aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct cgaaaacaaa
     4501 acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca ggaaacggaa
     4561 accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca ccaatatgaa
     4621 ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta ctggaacaat
     4681 gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat tcgttaccgc
     4741 aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg cccggtattg
     4801 gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt aggactaaga
     4861 aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac aattgaatcg
     4921 gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa tgaagaagac
     4981 cgtgtttatt tgacaccaag agggaccttt ttggggaaca atgtgtttga gcgctttttg
     5041 tttgaaaaat agtttaaaga atatttgttt tttatctgaa tttaaataaa aaaagttcaa
     5101 aaatacaata aaggactatt gaaacgttga tataactgga tttacatcaa ttatttagaa
     5161 ttagcactct tgtgtttaga gtgctaaaaa atggagtctt tctcttgaca ggagaagggc
     5221 ttcttgctat atttataagt ggattagcac ttagaatata tgagtgctaa tgagaggtga
     5281 ggaagatgtt aacaaagcga caaaacgaca ttttacgtct gatcatccaa cactatacga
     5341 gtagtggcgt gcccgttggt tccaaaacat tgatgtctga gggagtcaag gccagctcag
     5401 caacgattcg caatgatatg aaagcattag aagatgaagg attgctgttg aagactcact
     5461 cttcttctgg gcggattcca tctgctttag gctatcgtta ttacgtggat catttgttaa
     5521 aacctgctcg cgtagcagaa gatgatttgc tgctgattcg tcagtctcta ggcagagaat
     5581 ttcatgaaat caatgagatt attaagcaat ctgctgagat attatctgag ctgacaagct
     5641 atacgacttt ttcattggga cctgaaataa aagaccgccg actgactggc tttcgtatcg
     5701 tacccttgaa taatcgacag attattgcta tcgtcgtaac agatatgggg aatgtagaaa
     5761 gccaagtgtt cactcttccc gaatatatgg gaagtcagga actagaaaaa atggtacaga
     5821 ttgtaaacga ccgtctagtc ggagatcctc tgatgacggt gtaccataaa cttcgtacgg
     5881 agattccgat gattcttcat aaatatttcc aaacgacaga agggatgtct cagttatttg
     5941 acaccgttct tggtcatgtt tttgaagata aggtttatgt cagtggacaa atgaatctct
     6001 tggattatga gccccgtcaa gatcttgatc agttcaaatc gatgttttct tttatgaaag
     6061 actcagacgg acttacacaa atgatcactc cgatggatag caatattcat atcaagattg
     6121 gtgctgaatt aggcaatgat ttattgcaga atatgagtat gattcaagca agttacgaga
     6181 tagatggtca tggaagaggt acaatagcct tgttagggcc tactagtatg ccttattctc
     6241 ggatgttcgg tctagtcgat gtttatcgaa gagaactagc agctaaactt gctgattact
     6301 accgttcgct tgacttgtca aactcgtaat gtgaataacg aagctatttg cagctgatcg
     6361 ttctctcttt cttagtaaga gcaatcaaac agctgactga ataatgaaag gaagactgta
     6421 tcgtgaaaga aaatcaagaa gaactagata aagaaatgac agatgctcag ccagaaccgg
     6481 aaatcgatgt cgaagctgca gaagattcgg gtatttcaga agctgaagcg gaagaattcg
     6541 aaacagcgaa attaaaagct gagttagaag aaatggaaga taaatacttg cgggctcgtg
     6601 ctgaaatcgc aaatatggca aatcgaggaa aaaatgagcg tgagcaatta caaaaatacc
     6661 gttcacaaga tttagccaaa aaattacttc catcaattga caacctggaa cgtgcattag
     6721 ccacagaagt gtcagatgat caaggggcag gtttgaaaaa aggcgtggaa atggtcttgg
     6781 aaagtttgcg taacgcactg gaagaagaag gaattgaaaa aatccctgct aaaggagaag
     6841 cctttgatcc taatcttcat caagcagtac aaactgttcc agcgactgaa gatacaccag
     6901 ccgatacgat tgtagaagta ctacaagaag gctacaaatt acatgatcgc gtgttaagac
     6961 caaccatggt cattgttgca caataattgt gcggatataa aacttacact ttcaattaaa
     7021 gaaggagacg ttaattatga gtaaaattat cggtattgac ttaggtacga ctaactctgc
     7081 agtagcagta ttggaaggaa acgaagcaaa aatcatcgct aacccagaag gaaaccgtac
     7141 aacaccttct gttgtatcat tcaaaaatgg agaaatccaa gtaggggaag ttgcaaaacg
     7201 tcaagctgtg acaaacccaa atacgatttc atcaatcaaa cgccatatcg gtgaagcagg
     7261 ttacaaagta gatgtagaag gtaaatcata tacaccacaa gaaatctcag caatgatcct
     7321 tcaatatatc aaaggattcg cagaagacta tttaggtgaa aaagtcgaaa aagcagttat
     7381 cactgtgcca gcttacttta atgatgcaca acgtcaagca acaaaagatg ctggtaagat
     7441 cgctggtcta gaagtagaac gtatcgtcaa tgaaccaact gcagctgctc ttgcctatgg
     7501 tttagataaa acagatcgcg acgaaaaaat cttagtattc gaccttggtg gcggtacttt
     7561 tgacgtatct atccttgaac taggagacgg tgtctttgat gtattgtcaa cagctggcga
     7621 caaccatcta ggtggggacg actttgataa caaaatcatc gactacatgg tagcagaatt
     7681 caaaaaagaa aacagcattg acttgtctca agacaaaatg gctttacaac gcttgaaaga
     7741 cgctgctgaa aaagcgaaaa aagatttatc tggcgtatca agcacacaaa tcagcttgcc
     7801 atttatcaca gcaggagaat ctggaccatt gcatttggaa atgacattga cacgtgcaaa
     7861 atttgatgaa ttaacagctg acttagtaga acgtacaaaa gtaccagtac gtcaagcgct
     7921 aaaagatgca ggtttatcac aatcagaaat cgacgaagtt attttagtcg gtggatctac
     7981 tcgtatccct gcagttgtag aagcagtacg taaagaaaca ggaaaagaac caaacaaatc
     8041 agttaaccct gatgaagtag ttgctatggg tgctgctatc caaggtggcg tgatcactgg
     8101 tgatgtgaaa gatgttgttt tacttgacgt tacaccattg tcattaggta tcgaaacaat
     8161 gggtggagtg ttcactaaat tgattgaccg caatacaacg attccaacaa gtaaatcaca
     8221 agtattctca actgcggcag ataatcaacc agcagtagac atccatgtat tacaaggtga
     8281 acgcccaatg gctgctgaca acaaaactct aggaagattc caattgacag atattccagc
     8341 agctcctcgt ggtattccac aaatcgaagt aacattcgat attgataaaa acgggattgt
     8401 aaatgtatct gcgaaagatc taggtacaca aaaagaacaa aaaatcacga tcaaatcttc
     8461 ttcaggtcta acagacgaag aaatcgaacg tatggtaaaa gatgcagaag caaatgcaga
     8521 agcagataaa gctcgtaaag aggaagttga cctacgtaat gatgtagatg cattgctatt
     8581 ctctgtggac aaaacattga aagaattaga aggcaaagtg gacgaagaag aagtgaaaaa
     8641 agcagaaaca gctcgcgatg aattgaaagc cgctgttgaa gcaaacaaca tcgaagaaat
     8701 gaaaactaaa cgcgatgcat tgaacgaaat cgttcaaaac ttgactgtta aactatacga
     8761 acaagcggca caacaacaag ctcaagaaaa cccagaagca gctcaaggcg gagcagatga
     8821 tgtcgttgat gctgattttg aagaagtcga tggcgacgat aaataatcag ttcactgaat
     8881 ttcgagagaa ggccaaagtt gctactttgg ctttttcttt tgaaaaatag tttgaagtat
     8941 cggtttttgt ttcaaacaaa atatgatatg ataacaagcg acgtgaaaat gatgagaacc
     9001 aataggagga aagcctatgg caacaaaacg tgattattat gaagtcttag ggctctcaaa
     9061 aggagcatca gaagatgaaa taaagaaagc ttatcgtaag ctttcgaaaa aataccatcc
     9121 tgacatcaat aaagaacctg atgcggaaga aaaattcaaa gaagtatcag aagcatatga
     9181 gattttaagt gacccgcaaa aacgcgctgc atatgaccaa tacgggcatg caggcacaga
     9241 tccaaattac ggtgctggtg gagctggtgg cggatttggt ggattcggcg gcttctctgg
     9301 tggcggcttc ggtggttttg aagatatctt cgactctttc tttggaggag gcggtcggtc
     9361 agtcgatcca aatgcgcctc gtcaaggtgc tgatttgcaa tatacggtcg acttgtcttt
     9421 tgaagaagcg atttttggtg tagaaaaaga aatcaagtat aatcgggaag aaatctgtca
     9481 tacttgtggt gggaacggtg caaaaccagg cacacaacca actacttgtc ataaatgtca
     9541 tggtgcaggt acgattaatg tagaacgcca aacaccactt ggacgagtga tgagccgtca
     9601 aacttgtgat gtttgtcatg ggacagggaa agaaatcaaa gaaccttgtc caacctgtca
     9661 tggctcagga catgagaaga aagcacattc agttaaagtg aatgtaccag ctggtgtaga
     9721 agaaggacaa caaatgcgtt tagctggtca aggagaagct ggagaaaacg gcggaccatt
     9781 tggtgatttg tatgtggtct tccgtgtaga agaaagtgat atctttgatc gtgaaggttc
     9841 tgaaatttac tatgaattgc ctttaagttt tgtacaagca gctttggggg atgaagtcca
     9901 agtaccaact gtccatggag atgtgaaatt gaagatccct gctggaacac agacaggtac
     9961 gaacttccgt ttacgtggaa aaggcgctcc gaagttacgt ggtggtgcaa caggcgacca
    10021 acatgtcaaa gtaaaactga tcacaccgaa aaatctaaat gaacaacaaa gagaagcatt
    10081 acgtgcattc gctgaagctg gcggcatcaa agttgaagaa cagcaagaag acggtttctt
    10141 cgataagttt aaagatgctt ttggcgggaa aaagcggaag tagtttttct agtaaaaacg
    10201 ctaagtcatt aataattaaa aaccagacga acaatcatat gttcgcctgg tttttttgta
    10261 gttgtcatgt ttgtaccaac aaaaaagcca gctttagaat atgataatcg tcatagtttc
    10321 taggggtata accagtgaga gaatggaact tgttcaatcg atattgcaag gtgtttttat
    10381 gaataaataa ttcttctgag caatttttga tgcttccgtt atttttactg aagcatgcca
    10441 aagtcttctt gaacaaatgt acttcttctt ctgtcaggct tttcaaaata cgttttacat
    10501 ataatgttcg ttgatctgac gggattgctg gtaaaacgat cccgaggtct aaatcttcaa
    10561 aaaagcggat ctcgttcaca gattgatgga aagctatcca ttcgcaaact tgtttggcat
    10621 gaaggaaaga ttgcggtgtc tcttgctctg tataacaaag cgacccaatt ccaaagttta
    10681 gctgtaactg atacatttta ttaaactttg tctggatttt atcaagcaat gatagcaatg
    10741 aggctctgga aatccgattg actaggataa tgatttgttg tctatgtaca gtgagcaaag
    10801 cctgtccgta ataagagaag accctttcga gcaactccaa taaaggattg atccgttctt
    10861 gacacaattg ctgattgtca gaaagttgtc ccacaactac ataatatgga gaagaaaaat
    10921 caagctcaat taagtgaggg tggtatcgac tatgtacttg atatcatcaa tgaaccgatg
    10981 gtactttctt atgcgatgga acaggtagag cgattgcttg tttgtgcagg aaaacaagcg
    11041 atgcggctga tacgattagg tgagaaaata agaagataaa aatacacggt cccttcatgg
    11101 cgaccgtgca tttttggttt ttattaaata tttaatactt tattcaagaa atcttttgtc
    11161 cgttcatttt gcggattttc aaagatttgt tgaggcgttc catcttctaa aaagtttccg
    11221 tcgtcaatga acatgacgcg attggccact tctttagcga accccatttc gtgcgtaacg
    11281 ataaccatcg tcataccttg ttctgctaac tttttcatga cgttcaagac atcaccgacc
    11341 atttcaggat cgagtgcaga agtaggctca tcaaaaagca tgatgtcagg gttcatcgct
    11401 agagcacgag caatagccac acgctgtttt tgtccaccag aaagcatttc aggatacata
    11461 tcttttttat cttctagacc aactgtctgc agtaatttga ttgctttttt ctctgcttct
    11521 tctctagatt ctttcttcag gtccatcggt gctaaaatga tgttttccaa aatagaaaga
    11581 tgagggaata ggttaaagtg ttggaatacc attccgatat gttgtctcac caagttgata
    11641 tctgtgcttt tatccatcaa gtgggcgccg tcaataataa tttcaccgtc agaaggttct
    11701 tctaaacgat tcaagcaacg caagaatgta ctttttcctg aacctgaagg gccaatgata
    11761 cagacgacat ctccttcgtt gatggataca ttgatgtcgt ttaatactgt gttatcgccg
    11821 tattttttga ctaaatgctc aactaagatt ttttctgcca tcttacttca ccttcttttc
    11881 taaaactttt gctaattttg tcaatgctgt gatcaaaatc aagtacatga tcgcaatgat
    11941 caagtaaaca tacgtacttt gtgttgtacg tgcaacaatg atcttaccag tttgcagcaa
    12001 ttcgactaca ccgattgcgg aaatgatcgt tgtgtctttt aatgagataa cgaactgatt
    12061 gacgaatgat gggatcatga tgcgtatcgc ttgcggcaaa atgatttttt gcattgtccg
    12121 attataagaa agacctaaac ttctggaagc ttccatttgt ccgacaggaa cggcgttgat
    12181 cccgcctcga acaatctctg cgatataagc acttgcgtta agagtcaagg tgataacacc
    12241 agcaaggaag tcaggaatcg taaatccaac gataccaggc aacccaaaga aaataaagaa
    12301 cgcaagaacc atcattggaa ttcctcggat gatatcgaca taaatactag caattgtgcg
    12361 aagagcgcgt attggtgcta cactgaataa tccaaaaatc acaccgatta ctatagccaa
    12421 agcaaaggag atcaaagtta ggagaattgt tctccaaagt cctttcaaca atgcttgata
    12481 gttgttttgg ataagtccaa gaaatgttga ttcatcagca gtggaagact cactggaagt
    12541 ttctgaacca tccgctacat attctttaat aatcttatcg tattcgcctg ttctttttaa
    12601 ttctttcaat ccttcattga acatattaag aagctcagga ttttgtcctt ttttaacggc
    12661 aaatgcatat tttccgccag attctttttt gatcggtgtt tccaattctt gtccttgttt
    12721 gatcgcataa ccgattaccg gataatcatc catcattgca tcgattgcgc caacttttaa
    12781 cccgtcgtac aattgatcag cagcatcaaa atatttgata gaatagccat attcagattc
    12841 atggtcgctt aaaaattcag cactttcggt accaactttt gctccgactg tttttccttt
    12901 caaatcttca taagacttga tcgaagtatc tccttttttg acagctaatt ggatcccgct
    12961 atcaaagtaa gaatcagaaa aatcatagct tttctttcgt tcatctgtta cagtcattcc
    13021 ggcaatcatt ccgtctgctt gtcctgattc caaagcttgc aaagcagcag agaaaccacg
    13081 gtagtccatt cggatgttaa atccttgcag tttggcgatg ttttccatca attttacatc
    13141 gatgccttcg tactcgccct ttgcgttttg aaattcaaat ggagcaaaag cagagtcact
    13201 ggcaattacg tatacgtctt ttttgggctc tattttttgc attgtctcgc ttgtgcttga
    13261 ctctgccgtt gtagtgttgt cagcttgtgc aacatgacca aacgcaaatg tcacaagtcc
    13321 tgtcattaag aaaacaaatg agtgaaataa atgctttctt ttcataatca acctcctaaa
    13381 tttccaatat tttattatta taggcgaaaa gtgctgaatc agacaagact gtaagctcga
    13441 aaaaatgaaa aaaatgcgag tttctaacat tttatgttat aaaacataac atgtataata
    13501 agataaaaaa gtggcgaaag tatgttcggt gtggtataat tttttagtaa ggaatgcctt
    13561 tgctttcctt ttctttttat tggtcgtaaa atgaaaagga atgaatgaaa aggaggacga
    13621 agaatgattg agagagatac ctcccgacac tttgagcttg tctcgaaata ccaaccggct
    13681 ggtgatcagc ctgaagcgat taaccaatta gtggatggcg tagtcggcgg gaaaaaagca
    13741 caaatcttat taggtgcgac tggaacaggg aaaacatata cgatttccaa tcttattgag
    13801 aaagtgaata aaccaacact gattattgcc cataacaaaa cattggctgg tcagctgtac
    13861 ggggaattca aggaattttt ccctaacaat gctgttgaat attttgtttc ttattatgat
    13921 tattatcagc ctgaagctta tgtgccttca agcgatacgt atatcgaaaa agattcaagt
    13981 gtaaatgatg agatcgacaa attacgacat tcggctacta gttcattatt agaaagaaat
    14041 gatgtgatcg tcattgcatc cgtttcatgt atttttggat taggctcgcc ttttgagtac
    14101 caaaaacaag tagtttcgat tcgacaggga gcagaactag atcgcaatca gttgattcgt
    14161 gacttagtca gtatccaatt cgaaagaaat gatatagatt ttcagcgcgg tcgttttcga
    14221 gtgcgcggtg atgtcgtgga gatttttccg gcttcaagag atgaacgtgc cttacgtgtg
    14281 gagttttttg gagatgaggt cgaacgtatc cgagaagtca atgcactgac aggtgaagtt
    14341 ttaggagaaa cggaacacgt agcaatcttc ccggcgactc actttgtgac gaatgatgaa
    14401 catatggagc atgccgtagc gaatatcaaa gcggaattag aacagcgttt aactgtcttg
    14461 cgaaatgaaa acaaacttct ggaagctcaa cgtttagaac agcgaaccaa ttacgatatt
    14521 gaaatgatgt tagaaatggg ctacacgtcg ggaattgaaa attattctcg gcatatggac
    14581 ggacgtaaag aaggtgaacc gccttatacg ctattggatt tctttcctga agattttttg
    14641 atcgtggcgg acgaatcgca cgtaaccatg cctcaaatca gaggaatgta taatggtgac
    14701 cgagcgagaa aacagatgct agtagattac ggtttccgtt tgccatctgc tttagacaat
    14761 cggccacttc ggttagaaga gtttgaaaaa catgtcaatc agatcattta tgtctctgcg
    14821 acgccaggac catatgaaca tgaacaaaca gataccgtta tccaacaaat catccgtccg
    14881 acagggctgc ttgacccagt gatcgaagtt cgtccaatca tgggacaaat cgatgatcta
    14941 gtaggcgaaa taaatgaacg agtcgaaaaa gaccagcggg tgtttgtaac gacattgacg
    15001 aaaaaaatgg cagaagacct cacagattat ttcaaagaat tagggatcaa agtcaaatat
    15061 ttgcatagtg atatcaaaac gctggaacga acagaaatca ttcgagatct tcgattaggt
    15121 gaatttgatg tgttagttgg aatcaatttg cttcgtgaag gattagacgt acctgaagtt
    15181 tcccttgttg ctatcttgga tgcggataaa gaaggctttt tacgtagtga acgttcctta
    15241 gtccaaacga ttggacgagc tgctcggaat gaagaaggta aagtaatcat gtacgcagac
    15301 aaagtaacag attctatgcg tctagcgatg gatgaaacgt caagacgtcg tacgattcag
    15361 cagaagtaca atgaagaaca tgggatcgtt ccaaaaacga tcattaaaga aatccgagat
    15421 ttgatttcta ttacgaaaga atcggaagat gatacaaaag aagcggtaca agtctcgtac
    15481 gaagaaatga cgaaggaaga aaaagacacg ttattgatga aattagaaaa agaaatgaaa
    15541 gatgcggcaa aagctttgga ttttgaaaca gccgcgaatg tgcgagatat gattttagaa
    15601 ttaaaagctt caaagtagga ggacaacatg gctaacgata aaattacgat tcatggtgca
    15661 cgtgcccata acttgaaaaa tatagatgta acgattccac gagataaatt cgtggtcgtt
    15721 acaggtttgt ccggttctgg aaaaagttcc ctagcatttg atacgctgta cgctgaaggg
    15781 cagcggagat acgtagagag cctttctgct tatgctcgtc agtttttagg acaaatggat
    15841 aagccggacg tagatagcat cgacggattg agtccggcga tttctattga tcagaaaaca
    15901 acaagtaaaa atcctcggtc gacagtaggt actgtgacgg aaatcaatga ctatttacgc
    15961 ttgttgtttg cacgtgtagg acatccgatt tgtcccaacg atcatatcga gattaccagt
    16021 caatcagtag atcaaatggc agatcaagta atggctttgc ctgagcgcac aaagatccaa
    16081 gtgttggcac cgatcgtggt aaagaaaaaa ggacaacata aaaaaatatt cgaacgaatc
    16141 caaaaagagg gatacgtccg cgttcgagtc gatggtgaga tctatgattt aagtgaagtg
    16201 cctgagctgg agaaaaacaa aaaacatgat atcgcgatcg tcatcgaccg gatcattgtg
    16261 aaagaaggga ttcgttctcg cctatttgat tctttagagg cggccctgcg attagcagac
    16321 ggctatgctc tggttgacgt gatcggtgaa gaagaaatgt tgtttagcga acactatgcc
    16381 tgtccttatt gcggatttac tgttggcgaa ctagaaccaa gactgttctc attcaatgcg
    16441 ccttttggag cttgtccaga ctgtgatggt ttaggtgtca aattagaagt cgatcaagat
    16501 ttagtgattc cagatagaac gaagacactt agtcaaggtg ctatcgttcc atggaatcca
    16561 atcagctctc agtattatcc tcaaatgtta gcgcaggctt gtgaaagttt cggtatcgat
    16621 ttagatacac cattcgaaga attaccggaa gagcatcagg agatcatctt gaatgggaca
    16681 gatgatcttt tccatttcca ttatgaaaat gattttggtg gcgttcgcga tgtagaaacg
    16741 actttcgaag gggtattgaa gaatatcgag cgtcgttatc atgatacgaa cagtgatttc
    16801 acgcgtgagc aaatgcgtct ttatatgaca gaattaactt gtcagacatg taaaggttat
    16861 cgattgaatc cccaagctct atctgttcaa atcaatggaa cgaatatcgg gcaaacaaat
    16921 gagttgtcta ttcaaaaagc agtagatttc ttctcaaact taacgttatc tgaacaagag
    16981 aaagtaattg ccaaaccgat tttaaaagaa gtaaatgaca gactttcatt cttggaaaat
    17041 gtgggactag actatctaac tttgagtcgc gcttccggaa cattatctgg gggagaagcg
    17101 cagcgaatca gattggctac acaaattgga tcgaatcttt ctggagtttt gtatatttta
    17161 gatgaaccat cgatcggatt gcatcaacgc gacaacgatc gactgattgg ctcattaaag
    17221 aaaatgcgtg atcttggcaa caccctcgtt gtagtcgaac atgatgaaga tacgatgtgg
    17281 gcagcagatt atttgattga cgtcggacct ggggccggag aacaaggcgg acaaatcgtg
    17341 gctgcaggca ctcctgaaga agtagctaat gatgaaaatt ctttgacagg gaaatatctt
    17401 tcagggaaaa aatcaatccc tgtaccaaaa gaacgccgta aaggtaatgg gaaagcaatc
    17461 aagatcactg gtgcttcaga aaacaatctg aaaaatatta gtgttgaatt tccattagga
    17521 gaatttgtag cagtcacagg tgtgtctggt tctggaaaga gtacattggt caatagtatc
    17581 ttaaagaaat cgttagcgca aaaattaaat aagaattctg ctaagccagg taaattcaag
    17641 acaatttccg gctacgaaag tatcgaaaag atcatcgata tcgatcaaag cccaatcggc
    17701 cggacgccga gaagtaatcc agcgacttat acaagtgtat ttgatgatat ccgtgggtta
    17761 tttgctcaaa cgaacgaggc aaaaatgcgg ggttataaga aagggcgttt tagtttcaac
    17821 gtaaaaggcg gtcgttgtga agcttgtcgc ggggatggaa ttattaagat cgaaatgcac
    17881 tttttgcctg atgtctatgt tccttgtgaa gtatgtcatg gtaaacgata taattctgaa
    17941 acattagaag tgcattacaa aggaaaaagc attgctgata ttttggaaat gacagtagag
    18001 gatgctgtag aattcttcaa gcacattcca aagattcatc gcaaactgca aacgattgtt
    18061 gatgttggct taggttatgt gacgatgggg caaccagcaa cgacattgtc cggtggtgag
    18121 gcacaacgga tgaaacttgc cagtgaattg cacaaaatct ctaatggaaa gaatttctat
    18181 atactagatg aaccaacgac aggacttcat agcgatgaca tcgcccgctt gttgcatgta
    18241 ttacaaagat tagtagatgc tggtaacaca gttttagtga ttgaacacaa tctagatgta
    18301 atcaaaacag cagattatat cattgattta ggaccagaag gtggagaagg tggaggaacg
    18361 atccttgcga ctggaacacc agaagaaatc attaacgtaa aagaaagtta tacaggtcac
    18421 tatttgaaaa aaataatggt ataaagagga tagatagctg agatagttaa aaaaacataa
    18481 aaaaatgaat ttttgcttgt tttattaata tcagtgttct agaatcatta catggtagtt
    18541 ctttctacac tgattggtat agataaaaac ttcctataag ttcaatccgt tcaaaaaaga
    18601 attgagcaat cggaggactt tcctttgatt gcttttttct ttatggtatg atattccttg
    18661 tgtagttgga aaagaaaaac aagagattat gagtaagtga gagataatga tgaacagtat
    18721 tgaaaatgaa gaatttatcc ctatattatt aggaagcgac atgaacgttt atggtatggc
    18781 acgttctttt aatgaagcat acggcaaaat ctgccaagca tatgcttcgg atcagttagc
    18841 ccctacccgc tacagtaaaa ttgtcaatgt agaagttatt ccaggatttg ataaagaccc
    18901 tgtatttatc gagacgatgc ttcgtttggc aaaagaaaga tattctgata agagtaaaaa
    18961 atatcttttg attgcttgtg gtgatggata tgcagaattg atctcccaac ataaacaaga
    19021 gctgtcagaa tattttatct gtccatatat tgattattct ttatttgaaa ggctgatcaa
    19081 taaagtaagc ttttatgaag tttgtgaaga atatgatctt ccgtatccta aaacattgat
    19141 cgtcagagaa gaaatgttag taaatggaca tttggaacag gaattgcctt ttgaattccc
    19201 agttgctttg aaacctgcaa acagtgtgga gtatctttct gtccaatttg aaggaagaaa
    19261 aaaagctttt attttagaga ctagagaaga gttcgattta attttaggcc ggatatacga
    19321 agccggttat aaaagtgaaa tgattgtaca agattttatc ccgggtgatg atagtaatat
    19381 gcgtgtgcta aatgcgtatg tagatgaaga tcatcaagtt cggatgatgt gccttggtca
    19441 tccactatta gaagatccta caccagcatc gattggtaat tacgttgtga tcatgccaga
    19501 ttataacgaa aaaatctatc aaaccattaa ggcatttttg gaaaaaatcg aatatacagg
    19561 ctttgccaat ttcgatatga agtatgatcc tagagatgga gaatataaat tatttgaaat
    19621 caatttgaga caaggtcgta gcagtttctt tgtgacattg aacggcttga atctggctcg
    19681 ttttgtcaca gaagatcgag tgttcaacaa accctttgtt gaaacgacct atggaacgaa
    19741 tcaatcagat aaagcaagat tatggatggg tgtgcccaaa aaaatctttt tagaatatgc
    19801 tcgggaaaat gaagacaaaa aactagctga gcaaatgatc aaagaaaatc gttacggtac
    19861 tactgtattt tatgaaaaag accgatcaat caagcgctgg ttgttgatga aatatatgtt
    19921 ccataactat attccaagat tcaaaaagta ttttcatgtg aaagaaggct agttcatgga
    19981 gaattttttc agtattttag gcggaatggg cacgatggcg acagaaagtt ttgttcgctt
    20041 gatcaaccac cgaacgaaag ctacaaaaga tcaagaatat ttgaattatg tcttattcaa
    20101 tcatgcaaca gttcctgatc gtacagctta tattttagat cgatcagaag aaaatccaat
    20161 gccgtttctg ctggatgata ttgagaaaca aaatttattg cgaccaaact tcattgtgtt
    20221 gacttgtaac accgcacact acttttttga agagttacaa gcggcaacgg atattcctat
    20281 cttgcatatg ccaagagaag cagcaaatga acttgtccgt cagcatacga cagggagagt
    20341 agcgattcta ggaacagaag gaagtatgaa agctggaatc tatgaacgcg aagtcaaaaa
    20401 tcttggtttc gaaacagtga ttcctgatac tgcgcttcaa gaaaaaatca attacctgat
    20461 ctatcatgag atcaaggaat cggattattt gaatcaagag ctctattacg aaatcttaga
    20521 ggaagcggta gagcgcctaa actgtgaaaa agtcatccta ggttgcacag aattatcttt
    20581 gatgcatgaa tttgctgaag ataatcatta cccagtgatc gatgctcaat ctattttagc
    20641 ggatcgaacg atcgaacgtg cattagctga aagaagcgag gcattggata cagcatcgga
    20701 aaagtaaaaa aattggattt ggggcaaata tcctaaaaga tatttggtcc aaatcttttt
    20761 gtaaaagaaa aagaaaactg gtaatgatac gcccgggatg atataatttt attatgcaca
    20821 atgtgagagg ggttcgtaaa tatgacagat aatttgcaat tagtcatcat aacaggtatg
    20881 agtggtgcag ggaaaacagt agctatccaa agttttgaag atatgggcta tttttgtatc
    20941 gataatatgc cgcctcgatt gattccaaaa ttctgggaat tgatcaaaga atcaggtaaa
    21001 gtcacaaaaa tggctttagg agtggatttg cgttctcgtt ccttctttga agaaatccaa
    21061 aacatgctga tcgaaatcga aaatacgaac ttcatcgaca cttctatctt atttttagat
    21121 gcttcagacg aagaactagt ggctcgctac aaagaaacaa gacgagcaca tccaatggcg
    21181 atggacggtt tgatcactga agggatacgt aaagaacggg cgatactaga cgacttgaaa
    21241 gcccaagctt ccgtgatcat tgatacgaca acattgacac cacgacaatt acgtgaaaaa
    21301 atcaatgagt cattcaaatc aaagggagac caaggatttc ggatcgaatt tgtatcattt
    21361 ggttttaaat acgggttgcc gatcgattcg gatattgtga tggatgtgcg ttttttgccc
    21421 aaccctcatt atatcccgga actaagacca ttgaccggaa aagatcagcc agtctatgat
    21481 tatgtgatgt cctttgatga aacgcaatca ttctaccata aatttttgga tcttctggaa
    21541 actgtattgc ctggatacat taaagaagga aaaagcagct tgacagttgc aatcggctgt
    21601 acaggcggtc aacaccgttc tgtggcattg actgaacgtt tggcaaatgc tttagggaaa
    21661 aactataaag tcaatgtgac acatcgggac aaggataaaa ggaaagagac ggtgaaccgg
    21721 tcgtgaaaat gaaaacctac cggataagaa aaccaaagat cgtagtggtc ggcggtggca
    21781 ctggtctgcc agttatcctg aaaagtttac gaaatcaagg agcagatatc acagcagtag
    21841 tgactgttgc agatgatggt ggaagcagcg gtgcaatcag agaatcgatc gctatggctc
    21901 ctcctggtga cttgagaaat gtcttagtgg cgttatcgga tatgccacaa ttctatgaag
    21961 atattttcca ataccgtttc aaaaaggaag atcagttttt agccaatcat acgatcggta
    22021 atctgatcat tgccgcagtt tccgagatgc ggggaagcac ttatgaggcg attcaattat
    22081 tagcaaaaat gatgcatgta gatggacatg tttatccttc ttcagaaact cctttgacct
    22141 tgcatgctgt ttttaaagac ggaacgactg cagtaggaga atctaaaatc gcgatcaacc
    22201 gtaaaaccat tgaccgtgtg tatgtctgca acacaaatga taaaagtgaa gccaaagcgg
    22261 ctcgaaaagt cgtttcagca attatggacg ccgacatggt cgttttggga cccggaagtt
    22321 tattcaccag tatccttcca aatttagtga taccagaaat cggcgaagca atgctcaaga
    22381 caactgctga aaccgtctat atctgtaata tcatgaccca aaaaggggaa acggaacatt
    22441 tcacagatgc cgatcatata cgtgttttac acaagcattt gaatcagcct tttatcgata
    22501 cagtattggt caatacggaa aaagtgcctg aagattatat ggacccagag atctatgatg
    22561 agtatctagt acaagtcgca cacgacttca acggattgag aaatgaagga tgtcgagtga
    22621 tttccaccga ctttttagaa ttgaaagatg gtggtgtctt ccacgatgga gacaaagtag
    22681 tagaagaatt gttccgttta gttttcggtt caaaatatta agcaatttat tgttggagaa
    22741 aggaggagaa taggatgtca tttgctgcag atgtgaagaa agaactaact ggtttggaag
    22801 ttcatcgaga acatgcgaaa gcggaattag ctgctttgct gcgaatgaac ggctctttag
    22861 gtattgtgaa ccagcagttt attttgaacg tccaaacaga aaatgctgca attgccagac
    22921 gtatctattc tcttttgaaa gatcattatc aggtacgaag tgagctactc gttcgtaaaa
    22981 aaatgaaatt aaaaaagaac aatgtctata tcgtccggtt gaagcaaggc acaaaagatg
    23041 tgttgatgga tcttgatatc atggatggta tgatgttcaa tggacacgtt tcggacgaga
    23101 ttatgggaaa ttcgcaaaaa atgcgttctt acttacgtgg tgcttttatg gcctcaggtt
    23161 cagtcaataa tccggaaacg agtcgttatc atttggaaat attttctatt tatgaacagc
    23221 ataaccaaga catttgcgat atgttaaatt attacggtct acatgctcga acgcttgaac
    23281 ggcgcaatgg ctatatttcg tatttaaaag gagcagaaaa aattgctgat ttcttaacat
    23341 tgattggtgc aaccaactca atgctccgat ttgaagatgt tcgaatcgta cgggatatga
    23401 gaaattcggt caatcgtcta gtcaattgtg agacagcaaa tctgaacaag acgattgatg
    23461 cggcttctaa acaaatcgaa aacatcgaat tgatcgaagc aaaggtcggt ctacatgccc
    23521 ttcctgaaaa acttcaggaa atcgcagaac ttcggcttca acatccagag gtcagcttga
    23581 aagaattagg ggaaatgatt ccctcaggtg caatatcaaa atcgggaatt aatcaccgaa
    23641 ttcgcaaaat aaatgaattt gcggaaaaac tgcgtgaaga agcagtttaa tccaaagaaa
    23701 aaactgatac atgaagcagg agatgcgaat gtatcagttt tttttaaaag ctatacttgc
    23761 ttttcttccg tcaaactata attccaactt tactggagta acataatgtt gaaaggcttc
    23821 tattgttttt taatacaatc gtataaaaag cggggagaca actgaatgaa gattttagtt
    23881 ttatacataa acttttgctt aatatagaag tcctgatata gataggatca agtatttatc
    23941 tataactgga gattaattaa aaactggaag gaactgctcg atcaaccttg agaactgttt
    24001 ttcttacttc tggtcaagat tctcgtggtt ggtggataag gatggttgat aagttcattg
    24061 gattagctag tcgaaaacaa ccaggtgtaa ttaatgtaga agttttaaca aggggatgga
    24121 gtgatttatt cagtgataat cataagttca taaatagtaa ttgggatgta tggttggtat
    24181 acgttatacc tgaacttgaa ctatcaagat ttggtttaga atttgagaat cgatgtttat
    24241 aaagggaggg caaaaaatgt gcttttttac aacttttact atcattatga ttgcagtact
    24301 ttttattttt ctagatatag caaagcgaaa tacagcattt ttattatatc gggttttact
    24361 tcgagcaggt ctcataacat ttatatcgat cgttggattt tttctattca cagttattgt
    24421 atttatttgg agaactacag caccaccatt gccagagatt acatatggag aatttccgtt
    24481 tagtcttgaa tatgaaatag atgaggaaag aattttgatt gaagatacgg tgattgcaga
    24541 atttatagga agttttagag ggaatgtgac aactcaacct agacgaagtt ggagtataaa
    24601 acttttaaat aatagtggag agttgaaagc atttcattat gaattcttaa taatagaaag
    24661 tgaagatgta acaatcactt taagtagtgg ctctgctgga tattttatga atgatggtgg
    24721 aagcaagcca cagctcacag tccgtgatcg tattgcaggt tttatgcatt tttctcacta
    24781 tgacttagaa gaagctcgta aaatacttgc agaatatggg atcacattaa tcaattggga
    24841 atatgcgcca ccgataagaa attttttcaa tgattattat tagtcttata aaaaacagaa
    24901 tgtaaaattt atgtgcgcga gtatttagtt ttccattttt tgtttgatag atatatagca
    24961 ttgttgaagc atgggatagt ggtgccaatt ttatcaatga ggttggtcag gcagttaaca
    25021 taattggtga tgctataaat ccatttaatt ggaattggag gaattaggtg tggaaacagt
    25081 gagattatgg atattcatga aaaattttcg ttcggctttg agatatgtta ttctggaatc
    25141 aaaatcaggt tattatctga ttgacacaga tcactatact ttttggggag gctacctttt
    25201 tccgattttt aattggataa tcccccataa ggttatgaaa attaacttgc ctgcagaaga
    25261 aataaataga ttaatactca acaaagattt acaaaggaaa agagagaaag aacattctaa
    25321 tgttgcttgg ataggtccag catttgcagt agtgacttct tcaattgtcg gtcctatgct
    25381 agagagtatt tatagtgatt tttctattgg aatacgttat ttatttgtta ctttaagtat
    25441 agctgttctt ttgtgcataa agggttatgt tagcaagaag aataaagata ttttaacact
    25501 aatcggtgta aacaatttat ctagtactaa aattatactg tttcctgaat ctataaaaga
    25561 aggatcaagg ttgttgataa tttttataat gcttatactg ttttctgttt tatttggggt
    25621 gatgtttata gattattatt tgtcaaatta agcgagacaa aactttccat ttacgtaact
    25681 caaaaaaact tctaatggtg tttggtaatt tagtgatttt ctagggatat ggtttctttt
    25741 ggacgcaacg gatgagatga a
//
LOCUS       DARBDN010000028        24512 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000028 DARBDN010000000
VERSION     DARBDN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.028"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(128..976)
                     /locus_tag="SCH06_001206"
     CDS             complement(128..976)
                     /locus_tag="SCH06_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1077800.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1200..3140)
                     /gene="thrS"
                     /locus_tag="SCH06_001207"
     CDS             complement(1200..3140)
                     /gene="thrS"
                     /locus_tag="SCH06_001207"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEG1077801.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3477..3656)
                     /locus_tag="SCH06_001208"
     CDS             complement(3477..3656)
                     /locus_tag="SCH06_001208"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEG1077802.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3703..5526)
                     /gene="cadA"
                     /locus_tag="SCH06_001209"
     CDS             complement(3703..5526)
                     /gene="cadA"
                     /locus_tag="SCH06_001209"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEG1077803.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5804..8083
                     /locus_tag="SCH06_001210"
     CDS             5804..8083
                     /locus_tag="SCH06_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1077804.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8176..8823)
                     /locus_tag="SCH06_001211"
     CDS             complement(8176..8823)
                     /locus_tag="SCH06_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077805.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9002..9721)
                     /locus_tag="SCH06_001212"
     CDS             complement(9002..9721)
                     /locus_tag="SCH06_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077806.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9852..11003)
                     /locus_tag="SCH06_001213"
     CDS             complement(9852..11003)
                     /locus_tag="SCH06_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEG1077807.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11220..11960)
                     /locus_tag="SCH06_001214"
     CDS             complement(11220..11960)
                     /locus_tag="SCH06_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEG1077808.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11964..12287)
                     /gene="rsfS"
                     /locus_tag="SCH06_001215"
     CDS             complement(11964..12287)
                     /gene="rsfS"
                     /locus_tag="SCH06_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEG1077809.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12344..12937)
                     /gene="yqeK"
                     /locus_tag="SCH06_001216"
     CDS             complement(12344..12937)
                     /gene="yqeK"
                     /locus_tag="SCH06_001216"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEG1077810.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12921..13571)
                     /locus_tag="SCH06_001217"
     CDS             complement(12921..13571)
                     /locus_tag="SCH06_001217"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEG1077811.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13581..13892)
                     /gene="yhbY"
                     /locus_tag="SCH06_001218"
     CDS             complement(13581..13892)
                     /gene="yhbY"
                     /locus_tag="SCH06_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEG1077812.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13908..15017)
                     /gene="yqeH"
                     /locus_tag="SCH06_001219"
     CDS             complement(13908..15017)
                     /gene="yqeH"
                     /locus_tag="SCH06_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEG1077813.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15014..15541)
                     /locus_tag="SCH06_001220"
     CDS             complement(15014..15541)
                     /locus_tag="SCH06_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEG1077814.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15721..16506)
                     /locus_tag="SCH06_001221"
     CDS             complement(15721..16506)
                     /locus_tag="SCH06_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEG1077815.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16499..17368)
                     /locus_tag="SCH06_001222"
     CDS             complement(16499..17368)
                     /locus_tag="SCH06_001222"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEG1077816.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17369..18748)
                     /locus_tag="SCH06_001223"
     CDS             complement(17369..18748)
                     /locus_tag="SCH06_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEG1077817.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18756..19175)
                     /gene="fabZ"
                     /locus_tag="SCH06_001224"
     CDS             complement(18756..19175)
                     /gene="fabZ"
                     /locus_tag="SCH06_001224"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEG1077818.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19200..19676)
                     /gene="accB"
                     /locus_tag="SCH06_001225"
     CDS             complement(19200..19676)
                     /gene="accB"
                     /locus_tag="SCH06_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEG1077819.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19679..20914)
                     /gene="fabF"
                     /locus_tag="SCH06_001226"
     CDS             complement(19679..20914)
                     /gene="fabF"
                     /locus_tag="SCH06_001226"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEG1077820.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20933..21670)
                     /gene="fabG"
                     /locus_tag="SCH06_001227"
     CDS             complement(20933..21670)
                     /gene="fabG"
                     /locus_tag="SCH06_001227"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEG1077821.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21682..22599)
                     /gene="fabD"
                     /locus_tag="SCH06_001228"
     CDS             complement(21682..22599)
                     /gene="fabD"
                     /locus_tag="SCH06_001228"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEG1077822.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22706..22930)
                     /locus_tag="SCH06_001229"
     CDS             complement(22706..22930)
                     /locus_tag="SCH06_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEG1077823.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22983..23945)
                     /locus_tag="SCH06_001230"
     CDS             complement(22983..23945)
                     /locus_tag="SCH06_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEG1077824.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23955..24395)
                     /locus_tag="SCH06_001231"
     CDS             complement(23955..24395)
                     /locus_tag="SCH06_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1077825.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6715 a         5442 c         4262 g         8093 t
ORIGIN      
        1 attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa cactttgatg
       61 gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat aaaaaatagt
      121 aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt tttttcactt
      181 tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg atcgtagcaa
      241 attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt ggtctagatg
      301 tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc gtcaacgcaa
      361 tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct gcacttctac
      421 ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt tgcgggagca
      481 agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat ttttgcagaa
      541 tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc tctgccgatt
      601 ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact gtttctttta
      661 tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac tcatttgctt
      721 ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc gtgattttga
      781 agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc ggcgcactca
      841 acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca atattaccga
      901 taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata ctttcaatac
      961 gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta agtataccat
     1021 atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat ccgcccaaca
     1081 gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt tgaggaatac
     1141 ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa atttacctat
     1201 tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa gatattcaaa
     1261 tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc atcttccaat
     1321 tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc acgtatctta
     1381 tagcccattt tttcattacg atcatcaact tctacacgca accccttcat ttgcaaacgt
     1441 tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat gattgttgct
     1501 tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa ataagcgaca
     1561 aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg cgtattttcc
     1621 ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc taattgtata
     1681 gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag ttttggtccg
     1741 taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc catagcggct
     1801 ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt atctgtattg
     1861 tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc agcatatact
     1921 gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg acgaacaaat
     1981 gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa agcacctgat
     2041 ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc acgataagaa
     2101 tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg aagaacaagc
     2161 atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg atcccagtgt
     2221 ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg ttggtaacct
     2281 agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt tgcccctttt
     2341 ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa gtcaagttct
     2401 tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat atattctttc
     2461 aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg attgtttgag
     2521 tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat acggccagtg
     2581 gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata agcagtaatc
     2641 acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact tgcaaaaatt
     2701 tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc tttgacgatt
     2761 ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt ttgtccatta
     2821 tctgtatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg gatatttgga
     2881 tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac taagccaagt
     2941 gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat tggacgagtc
     3001 aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa gctttttgaa
     3061 atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac tgcaccatct
     3121 ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg atcagatcat
     3181 caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg acgaaaagtt
     3241 cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa cggtccgacc
     3301 gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc tggaaaagtt
     3361 tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt tctcatcaat
     3421 caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa ctaaacttat
     3481 tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat gatgacatgg
     3541 atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc tttcatcata
     3601 ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa tggcataatg
     3661 ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta tgtttgtctt
     3721 gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac tcaaaataga
     3781 gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta gtcccgtact
     3841 tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact gtttcgctat
     3901 tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat catctttcaa
     3961 gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca ttgcaatacc
     4021 gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca tcgcaacagg
     4081 tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca agctacgggc
     4141 atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag atccatcccc
     4201 ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg tctttgctgc
     4261 ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat caattgttac
     4321 atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg cacgtccaat
     4381 ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt ctttcagttg
     4441 actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag ctaagatatg
     4501 gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt ttattccatt
     4561 gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg ttttatcaaa
     4621 agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta caacgatccc
     4681 gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta gaatcagtgg
     4741 acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg agaaccacca
     4801 agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac gatcagctaa
     4861 acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa tcatttgata
     4921 ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc catttaaaga
     4981 ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac ctgtcaaaga
     5041 agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta caagttcgcc
     5101 aggcttgact agtaactggt catcaatatt tatttcatcg attactatat cctgcaattt
     5161 tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact gcagttcttt
     5221 acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca tgatcaatat
     5281 catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg taatcgctaa
     5341 tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa acatcaagaa
     5401 ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct ggtgaaaaac
     5461 aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt ttttgaaatg
     5521 tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa atttccagct
     5581 gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata ggccttaatt
     5641 gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac aaaaatattc
     5701 agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa aaactatgct
     5761 atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg agaaacaact
     5821 agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa atatgctgga
     5881 tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca cagctaatca
     5941 caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat atcgccaaca
     6001 tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac gcctgcaaac
     6061 gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag aagaccgtga
     6121 aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag aaacaatcgt
     6181 tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg gtcccgcatt
     6241 ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac aatttaaaat
     6301 ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg atgacttttt
     6361 gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct ctacgataca
     6421 aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga ttgaaggaat
     6481 cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt tgtatcataa
     6541 tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt tgttttctga
     6601 ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac agacattcaa
     6661 aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc aacaagaaag
     6721 tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat tgaccttagt
     6781 cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt tccgtgatat
     6841 gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt ataaagaaac
     6901 aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc tcctgaaaaa
     6961 attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc tggcggaaga
     7021 acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac aaaaggagcg
     7081 ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc gaatccatcg
     7141 agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact ttctacaaac
     7201 tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc aggaacattt
     7261 gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg ctgtactatt
     7321 ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc gctatatctt
     7381 tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag ccttgttccc
     7441 aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa atgaaacgat
     7501 cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc aattaacgac
     7561 aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg tgaaagaaca
     7621 tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag gaacaacaga
     7681 tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa aagcccggta
     7741 ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt atgctcaact
     7801 gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact ttatgaagcg
     7861 ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc gagttttctt
     7921 gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc tttacaccat
     7981 gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa gtcctttgtt
     8041 aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa gacaactgct
     8101 atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa aagtaattca
     8161 atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat attttaattt
     8221 gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg ggtcaaatac
     8281 cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat tccattcaat
     8341 gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca aaatctctga
     8401 tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt ctatcttctc
     8461 atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta atagtagaaa
     8521 gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag aacgacgaaa
     8581 aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt ccaccataca
     8641 ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat agccttcaac
     8701 gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca cagctaactc
     8761 ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga tttttgcttc
     8821 catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat acttatgctc
     8881 tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag caagacaatc
     8941 tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta aaactggttg
     9001 cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga tcttccagtg
     9061 catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc tcgttttgag
     9121 ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt aatgcttctt
     9181 gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct tcttccatta
     9241 catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca gcgtcttctc
     9301 ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg gaaacaccca
     9361 tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga ttcacattgt
     9421 tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca tagcgcaatt
     9481 cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca ataatatgtt
     9541 ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg tttgcatgcg
     9601 gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt gcataaatcc
     9661 ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat ttacgtccca
     9721 tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc tgttccatta
     9781 tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc ttctcatttt
     9841 tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg aatattgcct
     9901 cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc ctcttttttt
     9961 ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct tccagcatcg
    10021 gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc ttgctttttg
    10081 atattcagca agacataaca agataatcgt tggatccgtg tccatgtata tctttttgtt
    10141 tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt tttcatgcgc
    10201 gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt agaagataac
    10261 aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca agttgaaaga
    10321 tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc taacgcatgg
    10381 cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg atagcctgca
    10441 cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt ttcctttgca
    10501 taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc gggatacaga
    10561 ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga cagttcttga
    10621 aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact gctgtaatca
    10681 aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt ttgcaagatt
    10741 tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac gggaagctcc
    10801 actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt atcgatgata
    10861 gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac ctctgctcct
    10921 gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg attgtactct
    10981 acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata aaaaagaaat
    11041 agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata aactattctc
    11101 gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct atatcgttcg
    11161 gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag gcaaaaccgc
    11221 tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc ttcgtctgta
    11281 aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct taaataactt
    11341 tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg accagaccct
    11401 tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc gcttcctgga
    11461 taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata ttctggaaaa
    11521 acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt ttcttctaac
    11581 gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat atagcacagc
    11641 gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc gagcatattg
    11701 ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc aatcatcaac
    11761 atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa ggcaaccgct
    11821 aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg taaatgacgt
    11881 ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc gtaaatgaaa
    11941 gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac tagcggagca
    12001 tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa aacatgtacg
    12061 atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc aatacgtttt
    12121 acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc gttgatttga
    12181 cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac atttcgaacg
    12241 tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc aatttttaat
    12301 tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt tttgctaccc
    12361 agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca agcaaatggg
    12421 ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat gcaatggctc
    12481 gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct acataaatga
    12541 ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt gcatgaagaa
    12601 tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca agaccatgcc
    12661 agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg attaccattt
    12721 tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca atactagctt
    12781 tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct actccaagca
    12841 catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg ttttctctag
    12901 aataagcagt atattcatta ctatagtcca tattcataca acccttcatt ttgaatataa
    12961 tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat cttttgacgt
    13021 attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg atatggagta
    13081 tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt cagctcatcg
    13141 attttatacc attttggcaa atattctacc atatccccac cgataataaa gtaataatct
    13201 gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact tttcccacca
    13261 cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc taattccaac
    13321 atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg tggctgataa
    13381 gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc agccatcact
    13441 aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg ctttttcttc
    13501 tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt cttagcttgc
    13561 gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct ttgatacttt
    13621 tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac gatttcgcaa
    13681 tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt attttgaagt
    13741 aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac gatcattgct
    13801 gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc tttgctacgt
    13861 aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta aatcaatgct
    13921 ttgcgtttca atacatctac accctttggc gcccagcccg caattactac tggcgctgtt
    13981 acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac agaaaactca
    14041 aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg taataatcca
    14101 cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg aatatttaca
    14161 tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc aaatcttgca
    14221 agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg tttgatttct
    14281 tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat ttgatggcga
    14341 tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat ctcgatttta
    14401 tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc cgctgtattt
    14461 ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac gatatagaca
    14521 tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc atgagatttc
    14581 ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc acgttccttc
    14641 atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac tttgttccca
    14701 actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag tgaaccattg
    14761 aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa ttcattcagt
    14821 aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata atggcgtaat
    14881 ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa agccgtttgc
    14941 ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca gccgatacat
    15001 tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt tttgctaata
    15061 gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa ctatctgttg
    15121 cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca cgtatatcag
    15181 tcataatctg atcgcctacc attactatct catcatctgc taaatccaat tgtttctttg
    15241 ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa agatcaaatt
    15301 tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca acagggattc
    15361 ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct ggattattcc
    15421 atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga ttctttaatt
    15481 gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa tttgaaaaca
    15541 tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca accccgtatt
    15601 atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag aaaaagcatt
    15661 tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa caaaaaacaa
    15721 ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat ctaatcgaac
    15781 aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt tatatcgtgg
    15841 caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta actcgcgtag
    15901 ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac cgtctttcca
    15961 caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt ccagcatcca
    16021 gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac caatgatgat
    16081 ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa tagcctctcc
    16141 ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga tcaaggtaat
    16201 caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc gatagccttc
    16261 aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc ctttttgaat
    16321 accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa tcgcttcgtc
    16381 atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct cttcaaaaaa
    16441 atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat gtgctgtctt
    16501 atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg attttctgtt
    16561 tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag aattcagcct
    16621 tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt cttccagcaa
    16681 aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca aaactggcag
    16741 ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct tcattgctat
    16801 gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt ccttcttgca
    16861 tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt gttgctcgtt
    16921 cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg ataaaattag
    16981 gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca gtgaggactg
    17041 cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat tcgggaaatg
    17101 ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt tcatcaataa
    17161 tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga gggcatactt
    17221 tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac tttgcccaca
    17281 tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga ttgatccgaa
    17341 tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt tctggtgtcc
    17401 aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct atgactgcag
    17461 gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct gtgataaatt
    17521 cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca tggacgatta
    17581 tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa actgcactgt
    17641 ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc cctggagaag
    17701 gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg tgtccttgga
    17761 atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc acctgttttt
    17821 ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg attcgagtat
    17881 tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc gttccggcat
    17941 tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct tctctttttg
    18001 tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg cgttgtaaag
    18061 aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag atctgaactt
    18121 ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt ccaaatgccg
    18181 ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt gattgaactt
    18241 tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga taaccaattc
    18301 tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt cctggaatga
    18361 ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc attgcatcga
    18421 tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg gaggcaaatc
    18481 ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt gtcacgattg
    18541 cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc gggccaatgc
    18601 agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct gaatatatcg
    18661 ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg atttcaccgc
    18721 ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa ggttaattcc
    18781 gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc ggctgaagct
    18841 ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac tttcttacgg
    18901 aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg ttcaagagaa
    18961 agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc tggcataaca
    19021 ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt tttcttagca
    19081 acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat tggataacga
    19141 tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc ctgctttgct
    19201 tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc gttttctaca
    19261 aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag tttcatcgct
    19321 tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt gaaagctggt
    19381 ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac ctcgattcca
    19441 tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc ttgttcaggt
    19501 atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat attcatgcct
    19561 cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa atcgaattcc
    19621 gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat atccaaaatt
    19681 attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct aatgaattac
    19741 tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc aagtcaatct
    19801 caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct aatgccagca
    19861 aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc atcgatttcg
    19921 tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt gcttttgctt
    19981 ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg acttgttccg
    20041 gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca gaaccatctg
    20101 gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg atttctccat
    20161 agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga acgcctgctc
    20221 cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca cgattaggat
    20281 cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc tcacaaatcg
    20341 ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg ttacggaatg
    20401 cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta caaatacctt
    20461 ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc attggtacga
    20521 acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg ttttcgattg
    20581 ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga ttcatttttt
    20641 ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca tagatcgaaa
    20701 acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg aaatctttga
    20761 cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc ggtgcgatgc
    20821 cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca ataggtgaag
    20881 tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt tcttatccgt
    20941 gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga ttttgtgcta
    21001 agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc ggaatttgct
    21061 tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt gtgatgaatc
    21121 ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc acagattttg
    21181 ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata tttccaatca
    21241 acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc atttttttca
    21301 atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat tttttgaaat
    21361 cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg tttactaaca
    21421 catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct ttctcataat
    21481 cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt tcttctatct
    21541 tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct tttgcaaaag
    21601 ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca ttttttcctt
    21661 ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg tctgcttatt
    21721 ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc ttaatacttt
    21781 tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat ggatactctc
    21841 atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg tttctttctt
    21901 cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga attgaatctg
    21961 acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat gaaaaggccc
    22021 gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta aaacagcttc
    22081 gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat aatttgcagg
    22141 agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt caatcggcgc
    22201 attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca tataagcgcc
    22261 tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag ctactaatgc
    22321 cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat gctccttcaa
    22381 taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt gcgtctgatc
    22441 caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa tctcacttgc
    22501 ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca taccttgata
    22561 ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca atatatccag
    22621 aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc aggaaatgtc
    22681 ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa gtcactaaat
    22741 cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca tcttcaattt
    22801 cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg atgtcagtag
    22861 tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct tgaatttttt
    22921 cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta taatttaaca
    22981 gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc tgtaaatatt
    23041 actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc caataagata
    23101 gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa cttttcttgc
    23161 ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg atgcaaaagc
    23221 agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac gtctcgtacg
    23281 gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc tgaatcttct
    23341 gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact tctggtaccg
    23401 tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa gagaatccca
    23461 cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat tagcttagat
    23521 agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat tttttcagcc
    23581 atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc gatagcatga
    23641 gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta atcgggcgac
    23701 attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg ttttatcaat
    23761 ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca tcttcgttca
    23821 cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt ggaaagatca
    23881 ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat tccaaattgt
    23941 tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt cagtgcatcc
    24001 agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac catttcacga
    24061 tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc caactttaca
    24121 acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac taacttgtta
    24181 atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc tgaagttgtt
    24241 tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga cagatctttg
    24301 aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa gacactaaca
    24361 agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact aattagtttg
    24421 attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg caaccttaaa
    24481 agatcatttt tttactatat gagctttttt ta
//
LOCUS       DARBDN010000029        24193 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000029 DARBDN010000000
VERSION     DARBDN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.029"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            133..3660
                     /locus_tag="SCH06_001232"
     CDS             133..3660
                     /locus_tag="SCH06_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HEG1077826.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="SCH06_001233"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="SCH06_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEG1077827.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="SCH06_001234"
     CDS             7448..7789
                     /locus_tag="SCH06_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1077828.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="SCH06_001235"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="SCH06_001235"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEG1077829.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="SCH06_001236"
     CDS             9146..11566
                     /locus_tag="SCH06_001236"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEG1077830.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="SCH06_001237"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="SCH06_001237"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEG1077831.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="SCH06_001238"
     CDS             13000..13737
                     /locus_tag="SCH06_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEG1077832.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="SCH06_001239"
     CDS             13751..14566
                     /locus_tag="SCH06_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEG1077833.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="SCH06_001240"
     CDS             14579..15226
                     /locus_tag="SCH06_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEG1077834.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="SCH06_001241"
     CDS             15242..15898
                     /locus_tag="SCH06_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEG1077835.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="SCH06_001242"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="SCH06_001242"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEG1077836.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="SCH06_001243"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="SCH06_001243"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HEG1077837.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="SCH06_001244"
     CDS             18240..18758
                     /locus_tag="SCH06_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEG1077838.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="SCH06_001245"
     CDS             18865..19365
                     /locus_tag="SCH06_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEG1077839.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="SCH06_001246"
     CDS             complement(19645..20565)
                     /locus_tag="SCH06_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEG1077840.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="SCH06_001247"
     CDS             20730..21743
                     /locus_tag="SCH06_001247"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEG1077841.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="SCH06_001248"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="SCH06_001248"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HEG1077842.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="SCH06_001249"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="SCH06_001249"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEG1077843.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="SCH06_001250"
     CDS             complement(23383..24144)
                     /locus_tag="SCH06_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEG1077844.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
BASE COUNT         8003 a         4224 c         5108 g         6858 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaa
//
LOCUS       DARBDN010000030        23830 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000030 DARBDN010000000
VERSION     DARBDN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.030"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(54..788)
                     /locus_tag="SCH06_001251"
     CDS             complement(54..788)
                     /locus_tag="SCH06_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEG1077845.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="SCH06_001252"
     CDS             1115..1525
                     /locus_tag="SCH06_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HEG1077846.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="SCH06_001253"
     CDS             1518..2219
                     /locus_tag="SCH06_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEG1077847.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="SCH06_001254"
     CDS             2219..3805
                     /locus_tag="SCH06_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077848.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="SCH06_001255"
     CDS             3824..4045
                     /locus_tag="SCH06_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEG1077849.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="SCH06_001256"
     CDS             4042..4803
                     /locus_tag="SCH06_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEG1077850.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="SCH06_001257"
     CDS             5183..5692
                     /locus_tag="SCH06_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEG1077851.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="SCH06_001258"
     CDS             complement(5767..6306)
                     /locus_tag="SCH06_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEG1077852.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="SCH06_001259"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="SCH06_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEG1077853.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="SCH06_001260"
     CDS             7319..8170
                     /locus_tag="SCH06_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEG1077854.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="SCH06_001261"
     CDS             8198..8833
                     /locus_tag="SCH06_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEG1077855.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="SCH06_001262"
     CDS             8853..9626
                     /locus_tag="SCH06_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1077856.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="SCH06_001263"
     CDS             10034..10831
                     /locus_tag="SCH06_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HEG1077857.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="SCH06_001264"
     CDS             10809..11222
                     /locus_tag="SCH06_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEG1077858.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="SCH06_001265"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="SCH06_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEG1077859.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="SCH06_001266"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="SCH06_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEG1077860.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /gene="maf"
                     /locus_tag="SCH06_001267"
     CDS             15999..16559
                     /gene="maf"
                     /locus_tag="SCH06_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HEG1077861.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="SCH06_001268"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="SCH06_001268"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEG1077862.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="SCH06_001269"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="SCH06_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEG1077863.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="SCH06_001270"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="SCH06_001270"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEG1077864.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="SCH06_001271"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="SCH06_001271"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEG1077865.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="SCH06_001272"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="SCH06_001272"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEG1077866.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="SCH06_001273"
     CDS             21906..22484
                     /locus_tag="SCH06_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1077867.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="SCH06_001274"
     CDS             22536..23018
                     /locus_tag="SCH06_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEG1077868.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="SCH06_001275"
     CDS             23135..23509
                     /locus_tag="SCH06_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077869.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6649 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatagaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaata atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtttt
//
LOCUS       DARBDN010000031        23574 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000031 DARBDN010000000
VERSION     DARBDN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.031"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            200..1861
                     /locus_tag="SCH06_001276"
     CDS             200..1861
                     /locus_tag="SCH06_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1077870.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1931..2278)
                     /locus_tag="SCH06_001277"
     CDS             complement(1931..2278)
                     /locus_tag="SCH06_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HEG1077871.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2362..3303
                     /locus_tag="SCH06_001278"
     CDS             2362..3303
                     /locus_tag="SCH06_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077872.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3304..4347
                     /locus_tag="SCH06_001279"
     CDS             3304..4347
                     /locus_tag="SCH06_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1077873.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4353..5423
                     /locus_tag="SCH06_001280"
     CDS             4353..5423
                     /locus_tag="SCH06_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077874.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5413..6366
                     /locus_tag="SCH06_001281"
     CDS             5413..6366
                     /locus_tag="SCH06_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1077875.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6378..7388
                     /locus_tag="SCH06_001282"
     CDS             6378..7388
                     /locus_tag="SCH06_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1077876.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7673..8494)
                     /locus_tag="SCH06_001283"
     CDS             complement(7673..8494)
                     /locus_tag="SCH06_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEG1077877.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8591..8869)
                     /locus_tag="SCH06_001284"
     CDS             complement(8591..8869)
                     /locus_tag="SCH06_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077878.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9137..11146
                     /gene="metG"
                     /locus_tag="SCH06_001285"
     CDS             9137..11146
                     /gene="metG"
                     /locus_tag="SCH06_001285"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEG1077879.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11625..12212)
                     /locus_tag="SCH06_001286"
     CDS             complement(11625..12212)
                     /locus_tag="SCH06_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077880.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12387..13709
                     /locus_tag="SCH06_001287"
     CDS             12387..13709
                     /locus_tag="SCH06_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1077881.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13864..14640
                     /locus_tag="SCH06_001288"
     CDS             13864..14640
                     /locus_tag="SCH06_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEG1077882.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14633..15202
                     /gene="rnmV"
                     /locus_tag="SCH06_001289"
     CDS             14633..15202
                     /gene="rnmV"
                     /locus_tag="SCH06_001289"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEG1077883.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15195..16079
                     /gene="rsmA"
                     /locus_tag="SCH06_001290"
     CDS             15195..16079
                     /gene="rsmA"
                     /locus_tag="SCH06_001290"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEG1077884.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16530..17159
                     /locus_tag="SCH06_001291"
     CDS             16530..17159
                     /locus_tag="SCH06_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077885.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17283..18392)
                     /gene="ugpC"
                     /locus_tag="SCH06_001292"
     CDS             complement(17283..18392)
                     /gene="ugpC"
                     /locus_tag="SCH06_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEG1077886.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18601..19023
                     /gene="mgsA"
                     /locus_tag="SCH06_001293"
     CDS             18601..19023
                     /gene="mgsA"
                     /locus_tag="SCH06_001293"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HEG1077887.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19346..19882
                     /locus_tag="SCH06_001294"
     CDS             19346..19882
                     /locus_tag="SCH06_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEG1077888.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19922..21685)
                     /locus_tag="SCH06_001295"
     CDS             complement(19922..21685)
                     /locus_tag="SCH06_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077889.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21688..23403)
                     /locus_tag="SCH06_001296"
     CDS             complement(21688..23403)
                     /locus_tag="SCH06_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077890.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7606 a         4310 c         4789 g         6869 t
ORIGIN      
        1 taatggcttt tggaagacca tggaaaacct tgtacaaagc tattttttct gaaaaattcc
       61 ttgaaacctc acgaaaaaat cattatttta tgaaaaagac aaaaaaaagt gttgattttt
      121 taataattat tcattaaact cttaaacaac ttcagaaaat attaattatt ctgaaaattc
      181 caataaaggg gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg cggtatgcgg
      241 ccttgtactt gctggatgtt atggcggcag ttcagccaca agcagtagtt cagcaaaaag
      301 cggttcagca gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa tgcctacagc
      361 tgacttatca gttgcaacag atacaatcag ttttacagca ttgaataacg tttatgaagg
      421 aatttaccgt cttgatgaag acagcaaacc acagccggca ggagctagcg agttggcaga
      481 agtcagtgaa gacggattaa cttacaaaat caaattacga gaagacgcaa aatggtcaaa
      541 tggtgatcct gttacagcag cggattacgt ttatggctgg caacgaacag tagacccagc
      601 tacagcttct gaatatgctt acctgtatgc gccagttgaa aatgcagaag acattacagc
      661 tggaaagaaa gataaatcag aactagggat caaagcagtt ggtgactatg aattagaaat
      721 caaattgacg aaacaaacac catatttcca atatctgctt gctttcccat catttttccc
      781 acaaaaacaa tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa gtgataaagc
      841 tgtttataat ggaccattca cattagaaga ttttgatgga ccaggaacag atacagaatg
      901 gacttataag aaaaatgatc attactggga caaagataca gtaaaacttt ctgaaatcaa
      961 agtcagtgta gtaaaagaat cttctactgc attgaactta ttcaaagatg gccaagcaga
     1021 tgacgtgatc ttgtctggtg agttagcaca gcaaaacgca aacgatccag cttatacttc
     1081 tgttaaagaa gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga attcaccatt
     1141 caacaatgtg aacctaagaa aagctatttc ttattctatc gatcgtgaag ctttagtaaa
     1201 acaagtacta ggtgacggat cagttgtctc tacaggattg atcccatcag atatggtaaa
     1261 aagtccaaca acgaacgaag actttgcaaa agaagctgga aaattagttt cttatgacaa
     1321 agataaagca aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg attctttaga
     1381 atttgatttg atggcttctg atgatgattc atcgaaaaaa gtaatcgaat atgttcaaaa
     1441 ctcaatccaa gaaaacttgg atggcgtaac agtcaaacca acacctgttc cattctctgt
     1501 acgtcttgac cgctcaactt cgggtgattt tgacgcagta ctaggcggat gggctgctga
     1561 ctatgcagac ccaagcagct ttactgattt gtttgtcaca ggtaattcat acaaccgtgg
     1621 tcgctggagc aatgcagaat atgacgaagc agttaaagca gcttcatcaa cagacgctgg
     1681 cgatgaacaa gcccgttggg atgatttcca aaaagcaatc aagatcatct ctgatgatat
     1741 gggtgtcgtt ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa aaatcaaagg
     1801 tatcgttcac catgcggcag gcgcttcatg ggattacaaa tggacatacg ttgaagaata
     1861 atcgttaata ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc aacctcgttc
     1921 tcatattcac ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga gcaattagta
     1981 ttccggcaat gatcagccaa aagctgtaca taccgtagct ggcagacgag agcgaggaaa
     2041 attctggttt tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc tgaaaatgat
     2101 cgaagaaacc cgaagaaaag acccataaaa aaccgccgat aatcagaaac ggcaatgacc
     2161 ataagaatag atcattagat aattgaatga gtgtaaagga atggttgatg agatttttta
     2221 ttaaaataac cagaatcagt agaaaagcta ctgcgtaggg gatagatttt tttttcattt
     2281 gattgctcct ttatttttgg ttcattatct aataatgtag cgaaacatct gtcagaagtc
     2341 aaaagctagg gggaaacatt agtgaatagt tatatcaaat atgtattaaa acgtgtcttt
     2401 ttcatgatca tcacgctttg gttaattgca acaatcacct ttttcttgat gcaattgctg
     2461 ccgggcacgc catatacgaa tcaggaacgt ttgagtcctg aaacaatcga gatgctaaat
     2521 aaacaagtcg gtttggataa accagttatc gtacaatatg ggatttatct ttctaatttg
     2581 cttcaaggag attttggaat ttccttccaa tttaaaaacc agccagtcgc acatttgtta
     2641 gctggaagaa tcggaccatc cttgcagtta gggttacagg caattatctt tggaacagtc
     2701 ctagggacga ttttaggaac gatctctgcc atgaagcaaa atacatgggc agatacatct
     2761 tctacactcg tagcgatatt aggtcgttcc attccaaact ttgtatttgc tgttttatta
     2821 caatatatct ttgcaatcaa attacaagtt ttgccaatcg caaaatggga tggctttgtg
     2881 tacacaatct taccaacaat tgcgttggcc atgtcgccgc ttgctgactc tgctcggttt
     2941 atccgtacgg aaatggtgga agtactgcat agtgattatg tggaattagc aaaagcaaaa
     3001 ggattgagcc gttgggaaat cgcctttaaa catggtcttc gaaatagttt gattccattg
     3061 atgactttat taggaccgtt agctgtagca ttgatgaccg gatcactggt ggtagaaaat
     3121 atctttgcta ttcctggtat cggggaacaa ttcgttaagt caatcacaac aaatgattat
     3181 cctacgatca tggctgtaac gatcctttac tcatttatgc tgatttttgt tattttgatc
     3241 gtggatctat tgtacggtct agttgatcca agaattcgtg tttcagaagg gagccgagga
     3301 taaatggaaa tgataccaaa gcgttatgaa acagttgcag atatccctgc ggatgaattt
     3361 cttccattac aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc ttctttgaat
     3421 tttatccaag attcatggcg ccgtttaaag aaaaacaaag ctgccgttat ttcaatggtt
     3481 ttactattgg tcatcatttt gatctctgtg atcacaatct ttgtttctcc tcatgatcca
     3541 actgcccaaa acgtggctta tatcaatttg cctcctcgta ttccgggaat caatatcgat
     3601 ggattgaatg gaaaagcaat ggttggtggt gaacttgttg ataaatatgc tcaagcaaac
     3661 gtcccttcaa acgtaaattt ctttttagga acagacggtt tgggacgtga tgtattaagc
     3721 cgcttattta tgggaatgag aatctcgttg ctgatcgcat ttattgctgc attactagat
     3781 gtaacgattg gtgtagctta cgggttggtt tctggtttgt taggcggacg tgtcgataac
     3841 gtgatgcaac gttttttgga aatcttatca ggaattccaa acctcgttgt catgattttg
     3901 atgttggtcg tttttgaacc aggaattttt tcaatcgtgg ctgctatggc catcacaaac
     3961 tggataccaa tggcacgtat cgttcgtgca caaacaatga aattaaaaga tcaagaatat
     4021 gttttagctg gattgacatt aggtgaatca agaatgaaaa ttgcattcaa acatattttg
     4081 ccgaatatct ctagtgtcat tattattcaa atgatgttta gtattccatc tgctattttc
     4141 ttcgaagcct ttttaagctt tatcggttta ggtcttacgc ctccgtcagc ttcattagga
     4201 acgatgttga gcgaagggta caagacattc ctgtatctgc cttatctatt atggattccg
     4261 gcagtaactt tatcggttat catgattggc tttaacttac ttgctgatgg attgcgtgat
     4321 gcctttgatc ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa gtgaaagact
     4381 tagaaatctc ttttgatacg tatgctggaa aggtacgagc gattcgcggt gtcaattttc
     4441 atttgaataa aggagaaaca ttggcgatcg ttggggaatc tggaagtgga aaatcagtga
     4501 cgaccagaag catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct ggtcaaatcc
     4561 tctttaaagg taacgatatc gttggaaaat cagaaagaga gatgcaaaaa atccgtggta
     4621 aagaaatagc gatgattttc caagatccaa tgacctcttt agatccgacg atgcccattg
     4681 ggaagcaagt cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa gagggacaaa
     4741 aagctgcatt agaattgctt aaattagttg gaatacccga agctgagaaa cgtatcaaca
     4801 gttatccgca tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg attgcactgg
     4861 tatgttatcc ggaaatcctg attgctgatg aacctacaac agcgcttgat gtgactattc
     4921 aagcacagat tttggagctg ctgaaagaaa ttcagacaaa aatcgataca tcaattatct
     4981 ttatcactca tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct gtcatgtatg
     5041 gaggaagaat cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg caacatccct
     5101 atacttgggg actgcttggt tcaatgccga cattagatag tgcgaacgat cgattgtatg
     5161 ctattcctgg ttctccaccg gatttattga acccgccaaa aggagacgca ttctatccaa
     5221 gaaatgaatt cgcgatgaaa atcgatgcag aacaagaacc accatttttt gaactatcaa
     5281 aaacacacaa ggcagcaact tggctacttg ctccgcaggc acccaaagtg acaccgccag
     5341 aagaaatcca acgtcgctgg gctatcttta aagagaaaca aaaacatact tacggtcaag
     5401 gaggaattgc tgatgccaaa taaactactt gaagttaaag gattgaaaca gtatttcaat
     5461 gtaggaaaaa agaatgaagt acatgctgta aatgacatca gctttcacat ttatgaagga
     5521 gaaacattcg gtttagttgg agaatctgga agcggaaaat ccactactgg ccgtacgatc
     5581 attcgcttga atgaacctac tgatggtgag atattattcg acggtcaaga tataacgaag
     5641 atcaaagata aaaaaggttt gacgaaattc cggcatgatg ttcagatgat ctttcaagat
     5701 ccatacgctt cgttgaatcc tcgtatgaaa gtcagagata tcattgccga aggaattgat
     5761 gttaatggac tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga tctattgaga
     5821 actgttggat tgaatccaag ccacggtact cgttatcctc atgaattttc aggtgggcaa
     5881 cgccagcgta ttggtattgc acgagcattg gcagtaaaac cgcgttttat catttgtgat
     5941 gaaccaattt ctgcactaga tgtgtcgatc caagcccaag tggtcaattt gttgcaagat
     6001 ctccaaaaag aacatcaatt gacctatcta tttattgcac atgatttgtc gatggttaaa
     6061 catattagtg accgaatcgg tgtaatgcat aacggcttgt tattagagat gggaacaagt
     6121 gatgaaatct ataatcacgg tgttcatcct tatacagaaa gtttgttatc tgctattcct
     6181 ctaccagatc cagaccatga gagaaaacgc agaagaatca aatatcaacc tgaaccagat
     6241 gacggacaag tacgtcaact tcgtgaaatc gcaccagaac attttgtcta tgcaactgag
     6301 caggaagtcc catattacgc aaaaaaacta aaacgacaaa aggaatctct tctggttgct
     6361 aactaggagg gacatagatg ctaaaagctt ttaaattccg tatgtatccg acagaagaac
     6421 aaaaacagca attgattcgt acttttggat gtgctcgatt tacctataac catttgctga
     6481 aaaagcggca gaaaagttgg caacaaacag gagtagccaa tttttcgctc acacccgcta
     6541 cattaaaaaa agaataccca ttcttaaaag aagtagacag tcttgcttta gcaaatgcac
     6601 agcttaattt ggatcgggct tttcgcaatt atttcaaggg acgtgccagc ttcccaaagc
     6661 ttaaaacgaa aaaaagtatg tggcaatctt atacgaccaa caaccaaacc cgtacgatct
     6721 atctggaaaa tggctactta aagttaccaa aacaaaaaga actaatcaag ataaatcagc
     6781 atcggccagt tgaaggatcg attcgctccg ctacgatttc tgctcgatat aatgaagaat
     6841 tttatgtcgc actactttgt gatgtttcgc cagtaaaaaa agaatcttta gctaaatgga
     6901 tcgggatcgc ctatcatccg aagacattga tccaaacatc tcgacctcta gaagtaactt
     6961 taccaaaatt tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa ttgaatgtga
     7021 aagtccgctc cgctcaccat agaaagatca ggttagatca ggcaagcaat tatcagaaac
     7081 aaaagagaaa agtaatggat ctttatctga aacaaaagaa ccagcgagaa gattatcttg
     7141 aacaattatc tgggaaattg gtcaaacaat atgactactt atttgtagaa tcttttccaa
     7201 aagaagaggc acatgctgat ttttctattc acgactggca taaattaata acaaaattgc
     7261 gttataagtc ccaatggtat aataaaaaat ttcttttgat caataccgac ggagcagaag
     7321 aaagcaattc cgtaagaaag agccaagtag tagaaaaaat gggcagacat tcggttatca
     7381 agggataaaa aatgaatgaa actgatagga gcgttagggt tagccttgtt aataaaaagt
     7441 cttaatgact tttgtttcta ggaatttttc ttttgaagaa aagctcacta attatgacaa
     7501 accaataaaa caatagcaga aaaagttcgt acgagctttt tctgctattg ttaatttttt
     7561 attcagaaag tttacgaata catcaaaatt ctgaaacaaa aaacgtaact cacaaagagt
     7621 tgtttttgcg ttttttcttg aatgattagg tctgaatctt ttgctcacaa ccttattcat
     7681 ggtgccccgg cttgagctga tagatttttg aaggacggcc gattcctaca ggacgttcac
     7741 cgatctcatc gaaatattgg agcatagctt tcttaaaatt ggaatgatcg atcgttttat
     7801 aatcgatccc taagaattta gcaaatactt ttcgagcttc cgtaatcgtg aaatctttac
     7861 ctaaaacttg tagaacttgc ggctcgtgtt ccattttatt gactacacgg ttgaatgctt
     7921 tcaagatgat ttgactatgg tcaaaagcca aagtatcttt gccagaagac tctccagtga
     7981 ctaaatcaag cgagatagcc acttctccgc tagataaatg gatcttgtta ctatgacgtt
     8041 ctagtgtgaa ccagcgtact tccttggcat catctccggc gattagcggt tcttctccaa
     8101 taaaggctaa gtagctgact gtgacgaccc agcctcgcgg atctcgatta ggcgtactga
     8161 atgtatgcag ttgctcaata ttttcttttg aaataaccac accagtttct tcctttgttt
     8221 ctcttaagac gctttctcca gttgactcat ccttttggac aaagccacca ggcaatgccc
     8281 atgaatttcg ataaggatgc ccttttcttt ggatcaacaa aactttcagc tgatcttctt
     8341 ctttgttata gcacatcagt acgatatcga cagtcaaaga gggcttgtca tattctggac
     8401 gttcctgttt ttgataccag ttaagaaatt cttcttcact tgctttatgt tcataatata
     8461 atttttcttc ttctttagaa gcaaaacggt tcatctgacc acctccattg acagtaaaag
     8521 tactttttac cttattgtag cagactctga aaaaaaacca aggatttact tgaaaaatct
     8581 aggttatcat ttaaatatga aaaataaatg gaagtatgag attgaataaa aagaaaagca
     8641 gataaaacgg caatacttta taccgctctt cacgaatggc aaagaagcca caaataacga
     8701 tatatacgtc aatgataaaa cgcaaaatcc aagctgctgt cataaaactg ttcaaatgcc
     8761 catggaggtt aaaataacca tacatacgaa tataaaaata gctgaatatt aaatgtgcta
     8821 atgaaagaaa agcaatacta agtgtaaaaa aaagatgttt cttctgcatg attgttccag
     8881 tcccttacta agatagatag tctttattat accacgtgtg aggggagaaa taaaaagccg
     8941 ttttttagta gatatgaaac aaaacaaaaa cccgcattta ttcaacctat tcatcctttt
     9001 aaaggataga ttgaacgtag atagaagtcg tttatccagt ctttttcatt ttgaaaaaaa
     9061 gctaacagca tgcttttttt atggtatact agcaaggaaa cgaattcgca tcatgcgata
     9121 aaggaggaag agccccgtgg cagaaaagga aactttttat atcactacgc caatctatta
     9181 tccaagcggc aaacttcata tcggcaactc gtatactacg attgcatgtg acgcaattgc
     9241 tcgttataaa cggttgatgg gctttgatgt gttttatctc actggagtgg atgaacatgg
     9301 tcaaaaaatc gaaacaaaag cagaagaact aggtgtaaaa ccgcaagaat atgtagataa
     9361 aatggcggct gatgtcaaga aattatggaa aacgcttgat atcagttatg ataaattcat
     9421 tcgcacgaca gatgattacc ataaagcagc tgttcaaaaa atatttgatc gtttattaga
     9481 acagggagat atttacttag gtgaatatga aggctggtac tctgtttctg acgaagaatt
     9541 ctttacagaa acacaacttg cagaagtgta caaagatgac gaaggtaacg tgatcggtgg
     9601 taaagcgcca agtggacacg aagtagaatt ggtaaaagaa gaatcatact tcttccgcat
     9661 gagcaaatac gcagaccgtc tattggaata ctatgaagaa catcccgaat tcatccagcc
     9721 agaatctcgt aaaaacgaaa tgatcaacaa ctttatcaaa ccaggattag aggatcttgc
     9781 agtttcacga acaactttta cttggggagt accagtcaag agtgatccga aacatgtggt
     9841 gtatgtatgg atcgatgcat tatccaatta tattactgca ctaggatatg gctccgaaga
     9901 tgaaagtcta ttcgaaaaat actggcctgc agatgttcag atggtcggta aagaaatcgt
     9961 tcgctttcat acgatctatt ggccaatcat gctgatggcc cttgatttgc ctctacctaa
    10021 aaaagtattt gggcatggct ggctattgat gaaagacgga aaaatgtcta aatcaaaagg
    10081 aaatgtcgtt tatcctgaaa tgcttgtgga acgttatggt ttagatgcac tccgttatta
    10141 tttgcttcgt gctgttccgt ttgggtcaga tggtgtcttt acgccagaag attttgtttc
    10201 ccgtgtcaat tatgatctgg caaatgatct agggaactta ttgaatcgaa cgattgctat
    10261 gatcaacaaa tattgtgatg gactcgttcc tgactatgcc tcacttgtca ctccatttga
    10321 tagtgaactg tctacgacgg ctgctaacgt tgtcggacgt taccatgatg caatggaaaa
    10381 aatggaattc aatacagcat tggctgaaat ctgggtgctg atttctcgtg caaacaaata
    10441 cattgatgaa acagaaccat gggtattagc aaaagacgaa gaaaagaaag ctgaattgaa
    10501 tagtgtcatg atccatttag ctgaatcttt gcgtatcgca gcgatattac ttcagccaat
    10561 catgacagaa acgccagaga agatcttcaa tcaactagga ttggactctg aaacaatgaa
    10621 tcttgaagga ttacactttg gcgaatttcc ttcaggaaca aaagtagttg caaaaggtac
    10681 accaatcttc ccacgtttag atatggaaga agaagttgct tttattcaag aaaaaatgtc
    10741 tgaaggtact caaacaaacg aagatacagt caaatgggat ccagaagaaa cagaacttgt
    10801 ttcaacgaaa gaaaaacaaa tcaaatttga tgtatttgaa aaagtagaac taaaagtagc
    10861 agaagtcatc aactgtcaaa aagtagaagg ggcagataag ttgctgcaat tccgactaga
    10921 tgctggagac agccaagacc gtcaaatctt gtcaggaatc gctgaatttt atcctgatcc
    10981 aagcgaattg atcgggaaaa aagtcgtcat tgtagcaaat ctgaaaccac gaaagatgcg
    11041 tggacaaatc agtcaaggaa tgatcctttc tgcagaagca ccagatggct ctttacaagt
    11101 aatcgaagca ccaaaatcca tgccaaatgg ctcagaaatc gcatagaaat tcaaaggggg
    11161 tatgacacta gttgtgtcat accccctttt tccgaaattt gagaagcaat tttcgtaaat
    11221 tccttcttat tacttgaagc caatcatata atacagaaac agagaactat ccaaaataaa
    11281 tcctagaaaa agaagtacga gcttcgctga tttttgttaa tttagaataa tactaatagg
    11341 aatcgtaaaa acagaaaaaa agcataatga taaagggtcg ggcagatttt aattgattca
    11401 tctggtactc ttttttattg tccttacatt cataaagttt gaatgcaatg actttattac
    11461 atctatattt atatctaaca gtagcgttga tgtgttaatt ataagttcta tcactttatg
    11521 ttcaattagt ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa acaatcatcg
    11581 gctttgactt cgatgattgt tttctttatt ttgtaaaaat cctatcactt gattttatgg
    11641 taacctttta tttttgtctt caaacggctt ggtaagagag cagtaagcag tgcaaatggg
    11701 atcgaaaaga cataccagaa aatcgtacgt ccgataccat aatgttgata gagctttgtc
    11761 aacatcacgt gtaacaagat caaccctaaa agcaaggagc cagctataaa ccaatgatta
    11821 tcccaatgca tgacttcact aagtgccatc actccaaaag gatagaaata aaaatagatc
    11881 ccgactaagg tcatccgcca gttctttgta aatgttccga tattcaataa aaagaaaatc
    11941 gctgaaagca aaataccgat aggcggaaaa agcccaacca aaaaggaata caacatcccc
    12001 cacaagatca tcacaggacc tttgatcaat gcaacgattg cgatgaacaa agtcagcaat
    12061 attagttttt gtgataacgt tgcaacagtc attaatccaa ataaaattaa tgtgaaccaa
    12121 tgccaatggg actgctgttg ttctttacgg gaaaaatcga cccggttgga taaataatct
    12181 gctaatttcg gataagaacg cttaaaatcc ataaactgtt cctccttcgt ggaaaaggta
    12241 ggtttagtat acgaaaaata aaaaagaaat acatccgtct taagagggag tttttcactg
    12301 aaagtggaga aaaaagaatg gtaaattaaa atattctcag ttatactgaa aattatacca
    12361 aatttcaaag aagaaagagg atgggaatga aaggcaaact aaaacgagaa atcaatctgt
    12421 ttggcgcatt agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc ttcaaaactg
    12481 ctgctgttac tgctagtact cagtctacaa gtttgacatt gctagcttgg cttttgggtg
    12541 gtttcttaac gatctgtgct ggattgacag tggctgaatt agctacagca atcccggaaa
    12601 ctggtggagc tgtaaaatat attgaagctg cgtatggaaa attgcccagc tttttattag
    12661 gatgggcgca aagcttgatt tactttcctg ctaatattgc tgcattatcg attatctttg
    12721 cgacacaatt gacgaactta ttacaattat ctaccgatta tcttttgttg attgcagtga
    12781 tcaccgctgt ttctgtgaca gggttgaatt tgttagggac aaaagtcggt gcttctgtac
    12841 aatcagtgac gttgattgtt aaattaatac caattgctgt gattgtcata tggggattat
    12901 tgaccccagg acaaggaact gtccagttat ttccaatcga agctggaaaa gatgttactt
    12961 ttgtcgaagg attgagcagt gcgttgttag caacgttgtt tgcttatgac ggctggttag
    13021 gtgtcggtgc aatggcaggg gaaatgaaac ggccggaaaa agatttgcct aaagcaatta
    13081 ttcttggttt gagttttgta acagtcgttt atctattgat caattttgtt tttttgaaaa
    13141 ctttgccgat tgatcatctt gccggtaatt tgaatgcagc ttctgaagca tcagacgtca
    13201 tttttggagg aatcggtgga aagctggtca ctattgggat cttgatctcg gtatacggtg
    13261 cattgaacgg ttatacacta actgggatcc gcgtgcctta tgcgatggct ttagaagacg
    13321 agctaccttt cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt ccttatgttc
    13381 ctgcggtttt ccagttagca gtagcttgta ttatgatgag ccttggttct ttcgactttt
    13441 taacagacat gttgattttt gtgatgtggc tattcagttt actgattttt atcggtgtct
    13501 ttattttaag aaaaaaagcg ccggaattgc cacgtccata taaagtacca ctttatccaa
    13561 tcgttccgat tattgcgatt ctcggtgcta ttttcatttt aggtatgacg atgatgacgc
    13621 aaacgaaatt agcattgatc ggtataggtg ttaccttgat aggtatccca gtctattatc
    13681 aaaaaaagaa aaaacgctca gaagagtaaa atatttcaac aacagacaga aaaagtacga
    13741 actaggtcct ctagatcttc gtgctttttc tatttcaata aaacaagttc ttctattttg
    13801 atttttgcta cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa aggagagata
    13861 aacatgatat ttgattctca tacccattta aatgctgaac agttcaatga agatattcca
    13921 gaaacgattc agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt gggcttcgat
    13981 acgccaacga ttgaaaagtc tttgcaatta agccatgact atccaaatat atacagtatt
    14041 atcggctggc atccgacaga ggctggcagt tatacgaaag aaatcgaaaa taaattacaa
    14101 gaacaattga ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga ttatcattgg
    14161 atggaagacc cgaaagaagt ccaagataaa gtatttcgca gacagattgc tatcgcaaaa
    14221 gaaatgaacc taccaatcag tattcatact agagaagcac ttgaagacac gtatcaaatc
    14281 ctaaaagaag aagatgttcg agatatcggt ggaatcatgc atagtttcag tggtgattat
    14341 gaatgggcaa aacgatttct tgacttaggg atgcatattt catttagcgg tgtcgtcact
    14401 ttcaaaaaag cattagacgt ccaagaggct gcagcaaatg taccaatcga acgattactt
    14461 gtggaaacag atgcccctta tctggcacca gttcctttta gaggaaagcg aaatgaacca
    14521 ggctatactc gttatacagt agaaaagatt gctgaacttc ggaatcttcc gacagaagaa
    14581 gtggctgccc aaacatggac aaatgcgcac cgattatttg gtctaagcga acatggataa
    14641 gatgaagatc caagagatta tagtcgttga aggaaaagac gatacaagaa ggctgcggga
    14701 agtagttgat gcagatacga tagaaacaat agggtctgca atcaatgaag agatcctgat
    14761 gcaaattgaa catgcccaag agactcgtgg agtgatcgtt tttaccgatc ctgatttttc
    14821 aggagaaaaa ataagaaaaa tcattatgga agctgttcct caggcaaaac atgctttttt
    14881 gccgcgcaca caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc atgcaagtga
    14941 tgctgctatt ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc aaacggctgt
    15001 ttctgaaatc actagacaag accttttaga ctatggttta atagctgggg cacaagcaaa
    15061 agaaaaacga gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg gcaaacaatt
    15121 ggaaaaacgt ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag caatgaaaat
    15181 agtggaggaa caacatgagt gaatatcgtg aaattgcgac accctctaga acaaaagaga
    15241 ttttattgaa acatggtttt tcatttaaaa aaagtttagg acaaaatttt ctgactgaac
    15301 caaatatttt aaggaaaatc gtagaaactg cgcaaataga tgaacatacg aacgtgatcg
    15361 aagttggacc aggaatcggt gcattgacgg aacaattagc caagcatgca aaacaagtcg
    15421 tagcatttga gatcgatgat cgtttgatcc ctgtattggc tgatacgatg caaccctatg
    15481 acaatgtgac tattgtacat caagatattt taaagaccga tttgtcaaca gctgttagag
    15541 aaacatttca tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac tatattacga
    15601 caccgatcat gatgcatttt cttgaatcag atttggttgt ggatgaacta gtcgtcatga
    15661 tgcaaaaaga agtagctgat cgtatctctg ctgaaccagg aacgaaagct tatggttcat
    15721 tatcgattgc tgttcaatat tatatggaag ccagtttagc attcatcgta ccaaaaacag
    15781 tatttgtccc tcagccaaat gtagattcag cgattttgaa actgacaaga agagatatac
    15841 cggcagtcga agtgacagac gaaaaagcat ttttccgatt gacaaaagcg gcatttcagc
    15901 aaagaagaaa aacgctttgg aataacttgc agcattcgta tggcaaagat gaccagacaa
    15961 aagcatggtt agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt cgtggggaga
    16021 ctttgtcatt acaagaattc gccgcattaa gcaatgcgat gtcagaaaat atgcagtaaa
    16081 aaaagaggtt gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    16141 aaacaaaaat agttcctcat gtttttcgtt tgtttgggct tgttaccgca gatgcaagct
    16201 tttgaacacc gtttaagaaa gaggttgtgg gcctgccgtt taactctaag tcacaaggaa
    16261 caatttcaaa aaacagcttc tcatgttttt gagttagttg gtcttattac ttgatgcaag
    16321 cttttgacca ctattatgcc gaacaaggag atgtgacaca aattttgtca catctcctat
    16381 ttttgtttct tgatcaaaaa attcttatac ttgatactca cactcatttt gtatggattt
    16441 agaaaagaat atgtgtcttg acagttatta gtaagtgagt tatactaagt cgacatttat
    16501 gtgtcaagac atattaggag agagaaaaaa tgagaaaaaa ttcagttcga aaactaacga
    16561 tttctgcttt attgattggg atgggggtca ttatcccaat ggtcatgcct aaaatcatga
    16621 ttccaccagc ttcctttact ttggcgtctc atgtgccatt atttattgcg atgtttttta
    16681 caccaggagt tgcagtggct gttgcgctag gtacgacatt tggtttcttt ttaacaacgc
    16741 cggttatcat cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt ggggcttggt
    16801 acttgcaaaa gcatccgagt atcgttttaa aaaatggaca gtttactttt gctaattggc
    16861 gtttccaagg gttcaatttt gtgatcggtg tgattcattc tttagcagaa atgctagtag
    16921 tcagcatctt ttactttatt ggtaatatgc ctgaaacata ttattctcaa ggatattttt
    16981 atacagtatt catcttgatg gggattggtg ggcttatcca cagtttagtt gattataata
    17041 ttgcttattt tatagcagga acactcagca aatattttga tatccccgta tttacggcag
    17101 caaaaaaaga aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg acatattaga
    17161 catgatctct caaaaaaaaa actctcatct agtaatggat aataaatcct ctaagatgag
    17221 agttttttgt cctaaaaaga gctgcaccaa catcttctgg cacagctcta acagggggca
    17281 atttatggaa gtttgatgac ttgttctgtt tctttatcaa agaagtggcc tttgctgatg
    17341 ttgaaggcaa ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc tacttttgag
    17401 atgaactcag tagaaccagt ttttgtgtaa agcatcgttt cagctccaag taattcggaa
    17461 acgacaactt ctgatttcac tacggcttca ggtgaagctt caagggctac ttgttcactg
    17521 tggatgtctt ctggacgaat accgaagata acttcttttc cttcataacc tttttcaact
    17581 aatactttgt tttttccttc aggaatacga agcttaagcc catgtccatc tgtgataaca
    17641 ccatttttca atgtcacatt aaagaagttc atggcaggag atccaataaa gccggcaacg
    17701 aacatattga cgggtgtatc ataaacttct ttcggtgtac cgatttgttg gataaatccg
    17761 tctttcatga taacgattcg gtcagccata gtcattgctt ctgtctgatc gtgagtaaca
    17821 tagatggtcg ttgtttcaag acgctggtga agtttggcaa tctcagcacg catggctaca
    17881 cgtaatttag catctaaatt tgataatggc tcatccatta agaagacttt tgcatcccga
    17941 acgattgccc gtcccaatgc cacacgttgg cgttgtccac cagataaagc agctggtttt
    18001 cgtttcaagt attctgtcag acctaagatc tctgctgcat tgtccacacg ttttttgatg
    18061 tctgctttat catatttacg taatttcaag ccaaaagcca tattatcaaa aacagtcata
    18121 tgaggataca atgcgtagtt ttggaaaacc atggcaatat cacggtcttt aggtgccacg
    18181 tcattcatga cttttccgcc gatatttagt tctccttcag agatatcttc cagtcccgcg
    18241 atcattcgca aagtagttga ctttccacaa ccggaaggac caacaaaaac gataaattca
    18301 cggtctttga ttgatagatt aaaatcagtt acagaataat tttctgcatt gtcatatttt
    18361 ttatatacgt ttttcagagc catttctacc ataatacgtt ccacactttc ttttttagtt
    18421 ttattaacta tttaaagtat aaatgaaagc gttaactaac ttcaatgtca tgttgaacaa
    18481 gaattttttc ttttttttgt caatgtgcta gttttaagct ttaataaata tccataagaa
    18541 ataaaaactg atacactgga gtaaataagt atgttaacaa tatcaaaagg agtgtctctt
    18601 atgaaaatcg ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa attagcaaca
    18661 gcgtataaaa caatattgga aaaacatgaa ctttttgcta ccgggacgac tgggcagagg
    18721 atcacggaag caaccggctt gccgatccat cggtttaaat ccggaccgtt aggcggggat
    18781 cagcaaattg gagccatgat ttcggaggat cagttagatt tggtgatttt tcttcgagac
    18841 ccgctggctg cacagcccca tgaaccagat gtaacagcac ttatccgttt atctgatgtc
    18901 tatgagattc cgttagctac gaatatcgga acagctgagg tgctactaag aggactggaa
    18961 gccggcttcc tagattttcg aagaatcgtc catgaaatag acaagcatcc actttcattt
    19021 tgatggataa gcgtatggaa aaataacgtt taatgttcgc ctatatgtag ctataaaagc
    19081 taaacaaact gataatatgc gatataatac gaacgtattg gataatataa acaataatat
    19141 tagtttttcg tatttgcagt aaatgtgaaa atatgctata gtttctgtgg gaaaagatcc
    19201 caaaaataat acagagtaga aaataaagcg ttaagtgcta agaggatggg atgttgcctc
    19261 ttggacgaag gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg atacgatgta
    19321 gcagctctta aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac gtatgattgc
    19381 tattatgggc ttattgattg cattgatggt cactttgtcc cgactggtag caatcgagac
    19441 cccatttatt aaaatcagtg tcacatttat tccacaagtg atcatgggca ttctttttgg
    19501 tcctttttgg tcagggatag gcgcagtttt agctgattta gtaggaatgg ccctcttctc
    19561 gaaatctgca ttctttattg gatttacatt gaatgcattt attgaaggag caatctacgg
    19621 attctttttc tatcgaaaag agatcacttg gaaaaatgcc attctggcta cgcttagtgt
    19681 cacgctgatc atcaacttat ttttgacacc attatggctt gcgttgatgt accatgtgcc
    19741 attgttcagc tgggtcgttt gggcgccccg cctgttaaaa acagtaatat ggttaccgat
    19801 tcaatcaatt gccatttatt acgtaggacg tagtattcct tacaaaaaaa ttttaagaag
    19861 tttagcgatc cacgctaaat aaaaaacaag cagtcttccc atcccagaag actgcttgtt
    19921 tttattgtgc tgtgaattgt gcttgataga gccgtcggta ataaccatct ttttgaagca
    19981 gctcatcatg ggtgcccatt tcgacaatag ctccctgatc catcactaat atctggtccg
    20041 catttttgat tgtggacagg cgatgggcaa tcacaaaact ggtttttcct tccatcattg
    20101 ctaagaaggc ttgttggatt tttttctctg tcaatgtatc gactgagctg gtagcttcat
    20161 ctaagatcaa cataggggga ttactgatca tcgttcgagc aatcgtcaac agttggcgtt
    20221 gtccatctga tatctttaac ccttgaccgc caatcttagt atctaatttt tccggcaaac
    20281 gttctacaaa ttcatacata taagaggctt ttagggcatc attgatttct gcgtcacttg
    20341 cttccggatt cccaaaacga agattttctc gcaatgtact gtcaaatagc caagtatctt
    20401 gtaacaccat tccaaaactt ttacgtaatg tatcacgttg gatagagcgg atgtcatggt
    20461 catcgactgt aattgttcct tttgttgtgt cataaaaacg catcagcaaa ttaacaagtg
    20521 tggattttcc ggcccctgtt tttcctacta tagcaatggt ttgacctgga taagcagtaa
    20581 aattgaaatc ttcgatcaaa cgctgcttgg ggtcataaga aaaagaaaca tgatcaaaag
    20641 agacttttcc tttgatattt ttgggttcca aggcataggc atctggcaaa tcaggctttt
    20701 cttctggctg atcgatcaaa tcaaatgctc gttctagacc agaaaaagcg gtttgcagtt
    20761 gtgtcgtgat tccagaaagt tcgataaatg gtttagaaaa ctgacttgag tagatcgtaa
    20821 agctggaaat cacaccaaca gtgattgacg aaccactctt caatgccaat aggccgccaa
    20881 ctaaaccaat cgataaataa gcaaggtgat ctacaaaacg agaagacggg tttgtcaagg
    20941 aagaagaaaa ttgtgcccgt tgtccttttt catatagatc agcatttagc agttcaaatt
    21001 gctgttgact agcttcttct tgctgaaaag ctttcacgat tttctggtta ccgattcgtt
    21061 cggtcacaaa gcccgagata tccccaataa tcctttgctg tctatcgaaa tttgtttgtg
    21121 aagcacgagc aacgatccaa ctcacaagga aaataattgg tgtagaacaa agaacgacca
    21181 atgtcagaag tggacttaga cgcatcataa aaataaacga aagaatgatg attgccactc
    21241 cagaaaataa ttgattgaag gccgcagaaa ttgcaatgga aatattgtcc atatcatttg
    21301 taaatcgact gacgatattt ccgtgggagt tttgatcata ataacgaagt ggcaatcgat
    21361 tcagatgagc aaatgcatct tttcttaatt ttgcaacgga taagtaagct aaccgattgc
    21421 ttaacacttg gatgagccat tgactgacta cgttgattaa aacgatacca ccgaatagaa
    21481 taagtaaatg gaacagtcga ttgaagcgga cctgtccttc tccaatcatt tgatcgatac
    21541 tttgaccaat ttgtaacgtc atcacaactg ttgcaatccc attgatgatt cctagtatca
    21601 cagctagcca aatgtctttt gcataggcag taaggtaagg aatgaatcgg cggagcgtct
    21661 gcaaggataa tttttttact ttcataacta ttcttcctcc tgtgatgcga cgatttcctg
    21721 atattctgct gattgagcaa gtaattcttc atgggtaccc tgagcagcaa tcttaccttg
    21781 atccatcact aagatatgat gtgcttcttg aatagagcgg acacgttggg agataataat
    21841 cactgtactg ccaagataag tctgtagcgc cttacgcaaa tccaagtctg tttgataatc
    21901 caacgcactt aaagagtcat ctaaaatcag taatgctggc ttggcaatca aagctcttgc
    21961 aatcgtcagt cgctgttttt gtccgccaga gaaatttttc ccattttcca tgacttttgt
    22021 atctaaacca tttggaagct gacggacaaa ttcttctgcc tgagcgattt tcagagcttc
    22081 ccaacattct ttttctgtgg cgtctttctt accccattga aggttttcac gaatagtccc
    22141 ggtaaatagt acagaagttt ggggaacaag agcaatttgc tgacggagat gatccagctg
    22201 ccaagaacga acatccattc cgtccattat aactgtaccg gaactgacat catagaaacg
    22261 cggaatcaat tgtgtcaaag tcgttttccc gcttccggtt ggaccaatga ttccaaggac
    22321 tgtatttcgc ttcagctgaa atgtaatatt ttggagagaa agaccagaat caggagtata
    22381 acggaagtca acatggtcaa aagcgataat tgcttcagaa gaaaaatcgg gagtagtact
    22441 gacctcagct tcaagaatcg aattttctgt gtctagcacc tctttcaccc gatttcctga
    22501 agcttcggca cgtgtgaaga tcacgacgag gtttgaaaca acgatcagtg ccaaaagcat
    22561 ttgattcata taattgatca aagcaagaac ttgtccttgt tgcaagctac caatatttac
    22621 tttgatcccg ccaactgtca gcaaacagat gatcccgaca ttcatgatca aggttgtagc
    22681 aggtgataat agggcagaga tattggaaac acgtaaataa ttgttcgcta gatcatttgt
    22741 gcttttatcg aacttctctg tttctttttt tgtctgcgca aatgcgcgga tgacacgaac
    22801 accgctaaga ttctgactaa cgtgttcatt gagctgatct agtttttctt gcactttttg
    22861 gtagagagga acggtttttt tgatgataaa aaataaaatg attgagaaaa taggcaataa
    22921 tgctaagaaa aacagaccta cttcccagtc gatcacaaaa gccatgacca ctgacccgat
    22981 acttaaaaac ggtgctctga tcaataaacg aatgaccatt gctaaagcta gctgaagctg
    23041 attgatgtcg tttgtcattc gggtgatcaa ggtatctgtt ccaaaatgat tcaactcgtt
    23101 gtgagagaaa gtattgattt ttttgattag ctgattacgt aactctgtac caaatccttg
    23161 tgaagctact gaagcatagt attggcaaat gatagcacaa atcagaccaa tcacagacat
    23221 agcgaccatc cataagccca tttcaatgat ttttcctcgg tcattcattt ttagtccatt
    23281 atcgatcaag gaagccatca ttaaaggcag gacaagttcg aagacagctt caagaaattt
    23341 gaagaacggg cccaaaatga tttgcttacg atagtctttt gcataacgta ataactgaat
    23401 catatgattc ctcctattat ttatttgtcc acaattgaaa aaacaagtac taccacattg
    23461 tagcttagga aatttagaat gaaaagagaa caagcctttt cataaatgaa agttttatta
    23521 tgaagaagct ttagaaattg aatagactat tttttttaaa aaaaagaaaa tgag
//
LOCUS       DARBDN010000032        23382 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000032 DARBDN010000000
VERSION     DARBDN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.032"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            2..74
                     /locus_tag="SCH06_001297"
     tRNA            2..74
                     /locus_tag="SCH06_001297"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="SCH06_001298"
     tRNA            78..150
                     /locus_tag="SCH06_001298"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="SCH06_001299"
     tRNA            155..225
                     /locus_tag="SCH06_001299"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="SCH06_001300"
     tRNA            238..311
                     /locus_tag="SCH06_001300"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="SCH06_001301"
     tRNA            323..394
                     /locus_tag="SCH06_001301"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="SCH06_001302"
     CDS             660..1853
                     /locus_tag="SCH06_001302"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEG1077891.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="SCH06_001303"
     CDS             1983..3455
                     /locus_tag="SCH06_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077892.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="SCH06_001304"
     CDS             3538..4326
                     /locus_tag="SCH06_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEG1077893.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="SCH06_001305"
     CDS             complement(4393..5061)
                     /locus_tag="SCH06_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEG1077894.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="SCH06_001306"
     CDS             5176..6888
                     /locus_tag="SCH06_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077895.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8660
                     /locus_tag="SCH06_001307"
     CDS             6891..8660
                     /locus_tag="SCH06_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077896.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(8865..9431)
                     /locus_tag="SCH06_001308"
     CDS             complement(8865..9431)
                     /locus_tag="SCH06_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1077897.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(9431..10387)
                     /locus_tag="SCH06_001309"
     CDS             complement(9431..10387)
                     /locus_tag="SCH06_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEG1077898.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(10387..11043)
                     /locus_tag="SCH06_001310"
     CDS             complement(10387..11043)
                     /locus_tag="SCH06_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEG1077899.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            11413..13431
                     /locus_tag="SCH06_001311"
     CDS             11413..13431
                     /locus_tag="SCH06_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1077900.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    13501..13707
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13858..16272
                     /locus_tag="SCH06_001312"
     CDS             13858..16272
                     /locus_tag="SCH06_001312"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEG1077901.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            16620..18173
                     /locus_tag="SCH06_001313"
     CDS             16620..18173
                     /locus_tag="SCH06_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEG1077902.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(18554..20338)
                     /locus_tag="SCH06_001314"
     CDS             complement(18554..20338)
                     /locus_tag="SCH06_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077903.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(20353..22074)
                     /locus_tag="SCH06_001315"
     CDS             complement(20353..22074)
                     /locus_tag="SCH06_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1077904.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            22174..22935
                     /locus_tag="SCH06_001316"
     CDS             22174..22935
                     /locus_tag="SCH06_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEG1077905.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7392 a         4196 c         4858 g         6936 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaataa agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa
     8701 cagccaatca aaaacagctt ctcatgtttt tgatttggtt ggacttatta ccgcagatat
     8761 aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa cgctctaacc tgagtattag
     8821 agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt ttatttatct ttttttctca
     8881 atacaatata aaataggcgg ctggttcttt tggttgataa accgataatt cagcacatta
     8941 tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca tatccagttc tttttctcca
     9001 ccttcatgac catagtagac gacaaggatc aatcgtccgc gaggcacaag tcgtttcaat
     9061 atttcttcca tagctgtgcg tgtagtctct ggcatagtga tgattgcttt atcacttttt
     9121 gggagatacc ctagattgaa aatccctgct ttgagatttt gttgttcagc tatcacttct
     9181 cctaacgttt cgtggccttg tagaaacaat gagacacgtt cttctaactg acgctgttct
     9241 agcctttcac gagtagcatc gattgcttgt tgctggatat caaaactata gacatgacca
     9301 gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc cattgcccat cgttgcatct
     9361 acgacgtgat cccctggttg caagatttct tgcagtaatg tatggctgaa atgcaaagca
     9421 gtttgcaaca tcagacgctc acctttttcc gtacatcata ttttccttgg aagctatctc
     9481 tgcgaagaag ttcttcatca attgcattca agacttccca ttttttcaag ctccacattg
     9541 gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg atggatgatg atctcttttg
     9601 gtatcatttc cagctggtcg caaatgacat tgacatagtc aggacggctc attaattgaa
     9661 ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg catcagatgc atcaaatgga
     9721 gcttgattcc ttggatatct gaatctaaaa tggtgcgtct gacattttct ttcatcattt
     9781 ctaaactttc gcctggtaat ccgttgatca aatgcgtaca aacacggata ttatgtttgc
     9841 gtaatttagc cacgccatct aaataagttt gataatcatg tgctcggttg atcagttttg
     9901 aagtttcttc aaaagttgtt tgcaatccaa gttctaccca taaatacatc cgctcgttca
     9961 gttcagcaag gtaatcaact acttcatctg gcagacaatc cggtcgtgta ccgactgata
    10021 atcctacgac acctggtaaa ttgactactt gctcaaatcg ttctttgatt atttcaactg
    10081 gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta ttgttggaca tgaggccatt
    10141 tttgatgcat catgtcgatt tctttctgga attggattgg aagagggtct tcaggtgcaa
    10201 cgatcatgtc tcccgaacca gatacactgc aaaaagtaca accgccatgg gcaacagtcc
    10261 catctcgatt cggacagtca aatcctccat cgatcggcac cttgaaaatt ttcccgccaa
    10321 actcatttcg taaagcgtaa ttccaagaat gatatctttt atttccttct gaataaggaa
    10381 aagtcattaa aagtccttct ttctgtaaga gttatctatt tgttttcttt tttctctata
    10441 cactggataa gtcaggcaca gccaagaaag actgagtaag taaccgccga tgatatcagt
    10501 aggaaaatga acgcccagat aaatgcggct tatcccgaca cttactataa taaacatcat
    10561 cagcaattga agcaatgtgc gtaaggttct tttttgaaca aaagctggaa gcagaaatag
    10621 taaagaaccg taaagaatca tactgcctgc tgcatgtcca ctagggaaac tgtaacttgt
    10681 ttcaactact aagtgcgcca atgaaggacg ctctcgcatg aaaaatagtt tgatcaccgg
    10741 gttgatgatt ccagcaatta caataaatcc agaaacgaac caaaatgttt ctgccctttt
    10801 tttcttatac cacatccata aagccgcaca agcaaataaa atgatgacgg taagaggatt
    10861 accgaattta gtcataaaga gttggtagct gttcagatca ggataagaag ctctgacaat
    10921 gcctgtaaac cactgatcga aaccagaaag ccacgacaga tggaacttta cgatccagcc
    10981 caaaatgaaa aacaggacaa gaaagaagct accagccacc tgaaatgatg ttttatattt
    11041 catacaattc ctcctttgaa gcaatgactt attatagcat ttttggtcca gcgaaaaaaa
    11101 cggtaaagag ataaaaccaa tgtatgattc ctctttgaat aaccaatatt cttataaaaa
    11161 aaataactgt aatcggaaag acattttttg gtaatgcaaa tgaaatgtta gggaaataaa
    11221 atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac gtaggaagaa cttgaaaatg
    11281 aacagaagtt gttcattacg gtaaattaca atatgattac aaaaaacaac aaagctctta
    11341 aataactttt aataaatatt aagagaagtt ataattatta ataatagata aattgaagtt
    11401 ggaggataga agatggaaaa cattgcaaga aaagaacgga gacgtttaga acagaccaaa
    11461 cgttttcgaa aagcaaaacg aggggcagca atcgtgggaa ctgcgatggt aggctgttct
    11521 gtcgctgccc cattagtaca gccggttcct gttcaagcgg atgaaacacc tgttcagttc
    11581 ggcgcaagaa tcaatacagc ggcatttatc acagaaattg ctacttatgc tcaaccaatc
    11641 gctcaagcca acgatctata tgcatcagtg atgatcgcac aagcagttgt agaaagcggt
    11701 tggggcagta gtgcgttatc tcaagcacct tattataatc tttttgggat aaaaggcagc
    11761 tatcaaggac aaaccgtcta catggatacg cttgaatttt taaataatca atgggtaaat
    11821 aaaaaggagc ctttccgaca atatccttct tttgctgaat ctttcaatga caatgcctat
    11881 gtacttagaa atacttcatt tggcaacggt tattactatg ccggtacttg gaagagcaac
    11941 acgaaatcct atacagatgc gacagcttgt ttgacagggc gttatgcgac tgatcctggt
    12001 tacgcaggca aattaaataa tatcatcgca acttacggat tgacccaata tgatacacca
    12061 gctagcggaa acgcaggcgg tggagcgact acaggtggca ataatactgg aagtgcaggt
    12121 agtactggcg gttcaagcaa ttctggtaat acaaactcag gttcagcaac ttcgaccact
    12181 tatactgtcc aatctggtga ttctgtttgg ggaatctcaa ataaattcgg tatcacaatg
    12241 gatcaattga tccaatggaa caacatccaa aacaatttca tttatccagg acaaaaactg
    12301 acaatcaaag gtagccagga aaatggctct tcgacgaata attccggtaa caataccaat
    12361 tcttcaggaa atgctggtac atcaaacgga ggacaaacaa ctggtgcgaa atacactgtt
    12421 caatctggtg attctgtttg gaagatctca aatgatcacg gaattacgat ggctcaattg
    12481 attgaatgga acaatatcaa gaacaatttc gtttatccag gacaacagct aatcgtatca
    12541 aatggcggtt cttctaatgc tggagcaaat actggctcaa atactgggaa tacaagtggc
    12601 tctagttcgt ccagctcaag ttcttctaat acagcttcag gaacgaaata tacagttaaa
    12661 gccggagact ctgtttggag cgtctcaaat aaatacggaa ttacgatggc tcagctaatc
    12721 caatggaaca atatccaaaa taactttatc tacccaggac aacaactgac tgtttcaaac
    12781 agtggatcaa caaacagcac gtcaggtaat acaggttcgt caaccaatac aaataacagc
    12841 agttcagtta atactggcag cagttcgtct caaggcactt ataccgtgaa agcaggtgaa
    12901 tctgtttgga gcgtggcaaa taaaaacggc atcacgatgg atcagttaat cgaatggaat
    12961 aatatcaaaa acaacttcat ttatccagga cagcaattga tcgttaaagg tggaacttcg
    13021 gcaaatacaa atacaggttc aactacttct gcagcgaaac caaatacacc gaatacgtct
    13081 gctacgacaa gtacatcatc cactggtaat acgatgtata ccgtgaaagc gggcgagtca
    13141 gtttggagcg tagcgaacaa acatcatatc acgatggatc agttaatcga atggaataat
    13201 atcaaaaata atttcatcta tccaggacag caagtgattg tgaagaaagg ttcatctcaa
    13261 tcaacaaacc aacaatcagt tactggttcg aaaacctata ctgtgaaatc tggagaatct
    13321 gtttggagtg ttgctgacag tcatggaatt acaatggctc aactaatcga atggaacaat
    13381 attaagaaca actttattta tccaggtcaa acgttgattg tagctaaata aaatagctgt
    13441 tcgaagaaat aacgattgaa ttccacaaaa atatttgtta ctataaggct acttaaatat
    13501 gacaacactt gaaaaggaag tagtaaaaag actgaagttt cagagagcgc atggctggtg
    13561 agaatgtgca cggatgcttt tgaactcgcc tttgagttgc ccttgctgaa tacccgagta
    13621 agcaagcggc ggtgacggcc gttacaacgt tcgaggcctt ttcactaagg taaaattagg
    13681 tggtaccgcg tagattacgt cctataaaaa gagcaatctt tttataggat ttttttattt
    13741 cttttgtgaa gtttgagaaa acaaagcaaa aggaaataaa aataaacaga ttctgccggt
    13801 tttttcgtta tatttataat agaaacaagt gttttcaata gaacaggagg acagcaaatg
    13861 agttacaatc ataaagaaat tgagaaaaaa tggcaaaaat actgggcaaa aacgaatact
    13921 ttcaacaccc atgatgatcc tgaaaagcca aaattttacg cactggatat gtttccctat
    13981 ccatccggtc aagggctaca tgtagggcat cctgaaggtt atacggcaac ggatatcctt
    14041 tcacgtgtga aaagaagtca aggatacaac gtgctgcatc caatggggtg ggatgcattc
    14101 ggtctgcctg ctgaacaata tgcgctagat acaggaaacg atccagctga gtttacccaa
    14161 aaaaatatcg aaacattccg acgccaaatc aattctttag gatttagtta tgactggaat
    14221 cgcgaagtga atacaactga tccggagtat tataaatgga cacaatggat ctttacgaag
    14281 ctttatgaaa aaggtctagc ttatgaagca gaagtagcgg taaactgggt acctgaatta
    14341 ggaacagtta tttcaaatga agaagtgatc gatgggaaaa gtgaacgtgg tggctatgat
    14401 gtagtcagaa aaccaatgcg ccaatggatg ctgaaaatca ctgcttatgc tgatcgctta
    14461 ttggatgatc tagaattagt tgattggcca gaaagcatta aagaaatgca aagaaattgg
    14521 atcggtcgtt cagtaggagc aaatattgaa tttaaagtgg ctggtacgga taaatcctat
    14581 accgtattta cgacacgacc agatactcta ttcggtgcaa cttactcggt tcttgcacct
    14641 gaactagatc ttgttagaga aattacgacc cctgaacaaa aagctgctgt agaagcttat
    14701 atcgaagaga cagctaaaaa atcagatcta aagagaacgg atcttgcaaa agaaaaaaca
    14761 ggagtattta ctggtgctta tgcaatcaat ccagttaatg gcaaggaaat cccaatctgg
    14821 atcgccgatt atgtattatc ttcatacggc acaggagcca tcatggctgt tccagcacat
    14881 gatgaacgtg actttgaatt cgctcaaact ttcggactag aaattcttcc agttatcgaa
    14941 ggtggagatg ttgaaaaagc tgcttacaca gaagatggta cgcacatcaa ctctgaattt
    15001 ctagacggca tgaacaaaca agaagcaatc gataaaatga atgaatggct agaagaaaat
    15061 ggcgtaggga aaaaagaagt cagctatcgc ttacgtgact ggctattctc ccgtcaacgt
    15121 tactggggtg aaccaatccc aatcatccat tgggaggacg gaacagtcac agctgtccca
    15181 gaagaagagc taccattacg gttgcctaag acaaaaaaca tcaagccaag cggtactgga
    15241 gaatctccat tagcaaatat cgaggagtgg gtcaatgtcg ttgatcctgt aacaggtaaa
    15301 aaaggccgtc gcgaaacgaa tacaatgcca caatgggcag gaagctcatg gtattacctg
    15361 cgttatatcg accctcataa caaaaaagaa ctagcagatt atgaaaagtt gaagcgttgg
    15421 ctaccagttg acatctacat tggtggagca gaacatgcgg tacttcattt actatatgca
    15481 cgattctggc ataaattctt atacgatatc ggtgttgttc ctacaaaaga accattccaa
    15541 aaactataca atcaaggaat gatcttaggc gaaaacaacg aaaaaatgtc aaaatctcgt
    15601 ggtaatgtag tcaatcctga tgatgtggtc gaaacttacg gtgcagatac actgcgcatg
    15661 tacgaaatgt tcatggggcc attagatgct tcgattgctt ggagcgaaaa tggcttagaa
    15721 ggaagccgta aattcttgga tcgtgtatgg cgtttgatcg ttgatgagaa caataaaatg
    15781 cgtgaccgta tcactacatt gaatgatggc aagcttgata aagtgtatca tcaaacagtg
    15841 aaaaaagtga cagaagacta tgaaaatctt catttcaata cagcaatctc ccaattgatg
    15901 gtctttatca atgaagccta taaagtggac gctctgcctt atgaatatat cgaaggattt
    15961 gttcaactac tcgcaccgat tgctcctcac atgggtgaag aactatgggc aatccttgga
    16021 aatgatggtg gtatttctta cgcaccatgg ccaacatacg atgaagcagc acttgttgaa
    16081 gacgaagtag aagttgtttt ccaagtaaac ggtaaagttc gtgcgaaaag caatgttccc
    16141 cgagacttag gaaaagatga gctagaaaaa gcagcattag ccaatgaaat agtgcaagaa
    16201 tatattgaag gcaaaacagt cagaaaagtt attgcggtac caaacaagtt agtcaatatc
    16261 gttgctaatt aattggctct ttgtcaataa ggactgatga gttgtgcaaa atcaaatctg
    16321 ggccagaatg aacttcattc tgtctcagat tttttgttat ttcaaattga ttaattgatt
    16381 gatcaaaaag gttttgattt tcatgttctc aaacacgttc aatgtctttt tcttctgaat
    16441 ggtcttgtaa gagatctctg taatcatcaa atttttgtct attaatctta gtattttttg
    16501 atgtataaac tacctgaaat tgagagtaca taccaaattc ataaattttt tattagtggg
    16561 actagtgatt gtatggattt tgacgcataa tgaatgaagt atgagaaaag gagagacaaa
    16621 tggatcaaga actatttatt atcgaagtat tatcagctaa acaaaaaatt atcgagaaag
    16681 cgaaaaaaag agcgaaaaga ataatgttca agcttttaag cttagtattt ttctctggtt
    16741 tgcttttttt cggagctgta tcgttcctat atcgccatat gagtgcagta gtccgttcag
    16801 ctgaagggat gcaaaaatta aataatttgt atcacttttc gtggggagtt ggcggaataa
    16861 caattgttgt gcttattgtt tttcttctac ttatttggct ccgttaccat caattgtcgc
    16921 gtcatttcga tcaatggctt agtcaaagag cacaacagtt tttacataat aaaccaactt
    16981 ctcaagatga tgactatctt tattttgaga agacttcgac gagtcaagct tttcggatac
    17041 aaaaaagtga ttgccagtta ttgctgagat cacttgatga tttacctatc tacttaggcg
    17101 aaagcaaatc aaaattcgga atgaacacat tccatatttt tttactagaa aacgaaccca
    17161 gatgggaaaa aagccagtct tcgcctggtg gatacctgac aactaagatg agtacattag
    17221 tcactggttt tttcctcatt cttttagctg gaacaatcta ttatgggaga tacactcagc
    17281 caaaaatgtc ttctcatata aatgctgctt ctcacatgac aatgaactca actaacgata
    17341 cgcatataca aaagacaaat gaagggttgt tagctgatcc taagcaaaag gtaaatttga
    17401 caacacaaaa gataaatgat ctcaaacttg atacagagac gcactctctc tatatgacaa
    17461 cagatagtgg tgctaattgg gtatttgtgc cgattgattc gcaatggttg cgttttggcg
    17521 aatacaccct gacaacgggg ctgattcctg aaggttattg gatggacaac acatatgata
    17581 tttccgccga tttctcatgg tttatctatt cttctgggga tgatgtacgt ctgctgactt
    17641 caagagataa tggtaaaaca tggcaaacgt ctattatcac ccaatcagtt cagccgatac
    17701 gttatcgaaa agcggtattt tatggcaacg atggtctatt tatctgtaca tcagccagtg
    17761 ggatgtctgc agaaactttg tacatttaca ctactatgga tggcggaatc acttggataa
    17821 aaagtggaag tacaatgatc aatcagccag tacaaaatgt cagcttcgtt acaacttctt
    17881 taggttttgt ttcgacacgt gaaagtttgt tttatacaaa caacggagga cgctcattca
    17941 aagaatcagt tctgtcgatt ccggaaaact atcagacagg ggggatagat ctttttcaat
    18001 caccaaatga agttactcaa ataagcgcga atacgttaga gacaaaattt tatttgttga
    18061 aaaaaggacc aatcgatgca gggaaaatgt ttgcctgcct cttccgttca actgataacg
    18121 gggaaacatg gcaattcgtt cagcaactat cgcaagtaga acaaggagat taaagaagag
    18181 agattgtgag cctgacgttc agcaccgagt cacaagaaac aaattcaaaa aacagcttct
    18241 catatttgtt gaatagtgta actcgtgatt cggagttgac aagagcaaca agaagcgatt
    18301 ttgaagtata gcttctcgta ttttacaaga tcgtgtctta ttgccgatag gttgtctctt
    18361 gaacaccgtt tattcgtaaa aagggattgt gacaagtctt ttgtcactac ttaccgaacg
    18421 aaactgaagg agctatccaa aaagtatcat tagtattatt ctttgtgttt ctagtggcac
    18481 cactagtaca tttaaaaaag ctatcgatca tggactaatc atacatgatc gatagctttt
    18541 tagataatgt ttgttacgct atctgaaatt gactattata aagactggca taaagcgttg
    18601 gtgattggag tagttcagaa tgtgttcctt tttcgacgat atcgccattc ttcattacaa
    18661 ggatcatgtc tgcattttca atcgttgaca aacggtgtgc aatcacaaaa cttgtcctat
    18721 cttttgtcac agcttccatt gcttgctgaa tcaatgcttc tgttcgtgta tctacgctag
    18781 aagttgcttc atctaaaata acgacaggag gattcgctag aatgactcga gcaattgtca
    18841 ataattgttg ctgtccttga gataacgtgc cgttttcgct agaaatgatc gtatcatatc
    18901 cgtctggcag tgttcgaata aagtgatcac attgtgcgat ttcagccgct tcgataattt
    18961 gttctcttgt ggcatccatt ttcccgtagg cgatattatc agctaccgtt ccttcaaaca
    19021 gccaggtatt ttgtaaaacc atcccaaaag aacgacgtag ttctccacgt gaaagcttgg
    19081 taatatcaag accgtcgaat tcgatctttc ctttattcag ttcataaaaa cgcatcagca
    19141 gattgactaa agtcgttttt cctgcaccag ttggaccaac gatcgctacc gtttgttttg
    19201 gctttactga aaaatcgact tgattcatca atattttatc tgatgtgtaa ccaaactgta
    19261 catttttgaa agctattttt cctttcggtt gttctaaaag tcttgcatct ggaaggtctg
    19321 gaatttcatc tgtttcatct aatatctcaa atatcctatc gattgctgcc attgcggatt
    19381 ggatcgagtt gatcacataa gaagcggtag aaattggttc agaaatctga ttgatgtact
    19441 gaagataagc ttgtaagaag ccgatcgtca caccacctga tagaacaagc atagcaccga
    19501 ataccgcact tatgatgaag gcgagttgat taatgaaacg aatggccgga tagatagcac
    19561 agttcataaa ttgagcacgt ttaaaagcgt tgtattgctt tttatttact tcgtgtatag
    19621 cagcttctgc atgagcttgc tgattgaatg ttttgaccac tagattacca gctaagattt
    19681 cttccattcg attatttaaa acacccagtt catactgatt ctgttcagaa atctgtttgt
    19741 ttttgttcgc aatcttagtt gtaacaattg aactgccaac gatcagcaat aagacgagca
    19801 aagtaagctt gctttcgata taaaacagca tcagaccagc agcagctatt gttacgacag
    19861 aagtaaaaaa ttgattgata cctgtcaata acacttgaga aagttgattg agaccggtag
    19921 ttgtccgact aatgatgtca cctacttgat gattgtcaaa aaacgacatc ggtaatgttt
    19981 tgaatttttt tgtgatttct tttcgcaccc tcaatgtgat cttttcgctt aacgctgcca
    20041 ttgtccgttc ctgaataaat gaagtgatgc tgcttaagac tgaacagccg atcagcaata
    20101 agacagggaa caacaatgct tgtttgatat cactgaaaga aagctgtcca atacctgttt
    20161 ttcttatttc tgataagaga tcatcgatcc cgattcccat gatcaagggc atggctacga
    20221 ctaataggtt cccgaataaa ctgcatagaa acaatccgta aaaatattta tgttcaggtt
    20281 tgatcatttt ccaaaaacgt atcaaagcac gcgtgttcaa cgtttttttc ttttccatcg
    20341 tatcccttct ttctatattc cttgtgattt tgcaaactcc tgataagttt ggcaattaga
    20401 cagtagttct tcatgagtac cttgtccaac gatttttcct tcatctaaaa caatgatgtt
    20461 atctgcttgt tggattgtac tgaggcgttg agcaacaatc acgagagttt tctccgacat
    20521 gtgtttatga agggctgctc ttaatgctgc atctgtttta tagtctaaag cggagaaact
    20581 atcatcgaat acatagatct ctgctggttt gatcaacgct cgagcaatac atatccgctg
    20641 tttctggccc cctgaataat tagaaccgcc ttgagcaaca aagctgtcca atccgtcagg
    20701 aagggtgtcc actagttctt ctaattgagc gatcttgatc gctttagaca actcttctgt
    20761 tgaggcatat tcatttccca tctgcaagtt gcttaaaatt gtcccgctga ataagaaagc
    20821 cttctgaggg acataactga tgtgggagcg gatctgttct tgagtcattt gagtaagagg
    20881 aataccacca agggttactt ttcctatcgt agggtcacta agtctcaaga gaagtttcgc
    20941 caaactactt tttccagatc cggtcccgcc aacgatcgct gttgtttttc ctttaggtat
    21001 tgtgaaatca atatcttcta gaactggatc agagatttca gtatatttaa atgtgacatg
    21061 ttcaaaagca gctgcatttg tctgatcaaa ggttggttca gctactgttt tgatcgtctc
    21121 ttcctcaatt tcgatctctg cttgcagtat ttcttctatc cgtcgtaatg aggcaaacga
    21181 tttagggata atgaccaata ccatagctgc gatcatcaag taagcaagtg tcagcataga
    21241 gtattcgact acagcagtca cgacaccgat ttgtaatgct ccttctgcta caagatttcc
    21301 gccaaaccac aaaatagaag cataaacgat tcccatgagc aaaaaagcaa ttggagtgac
    21361 ccaagcaaat attcggttca ctttgatcat ttgattagca tagtcagcaa agctcttatt
    21421 cgttcgcttt tcttcatatg attgattatc aaaggcacgg atcatattaa tcccagtaaa
    21481 gaattctctc aatgtgatgg tgatccgatc catttttggc tggatactca aagataaagg
    21541 tgcccctcgt ttcatcagtc gataaacaat ccatacataa aaaacaacag agatcaatgt
    21601 aacccatgtt agtaatagag aataacgaaa catcatgaga atggtgaaaa cgcaaataac
    21661 cggtgctggt aagatcattt ggcaaaataa aacaatcatt tgctggacat tatcgacatc
    21721 attcgtcatt cttgtcaaaa gagatccaga actaaaacga ctgatatcct tcattgacag
    21781 ctgttggaat ttacggaaat atttctcccg cgtttggaat ccaaacctag cggaagccaa
    21841 tgctgaaaag taactagagg caactgcagc gattgttcct agaaacgcta caagcagcat
    21901 ttcaactcca atttttttta taactgaggc ttcgccactt gctatacctg tgtcgatcag
    21961 ctttgctact aattttggta cacctaatgt accggcgatt tctaaacaga tcatcacaaa
    22021 ggtaaggaga gcgagtcctt tgtttttctg taagaatgtt tttaagatag acatattatt
    22081 cctccttttt tcctgatact tttcgattct ataccttcaa gtaacttgaa ggtcaataga
    22141 aaaaagaata aactgaaaaa gaggtgagaa aaaatgaaaa aaatgtatac gattggccaa
    22201 gtatcggaac tatttgattt gccaaaatca acgatccgct attgggatga acaaggatta
    22261 atccgttcaa gtagacaaga agagaatgat tatcgattgt ttgatatcga tgatattttt
    22321 atgctttatg atatcgtttt ttatagaaaa ttagatatac cgatcaaaca gatgaagaat
    22381 ttatatggaa aaacattgac ggagttatat gagacacttg atgaaacaga aagaagaatc
    22441 cataaagaac tggtggtgat gaaacaaaaa caaaaagaga taagggagca aaaaaaacag
    22501 ttgaaattga tgatcgatac aaacgaggaa gaatttcctg tagaagagat cccttttgac
    22561 tgtatgatct caacggagtt tgaagatatt gtggaaatca aaaaatttct acctaactat
    22621 tcaagctttg ggatgatgag tatgccagct tccagttcac agacgatgta tggatttttt
    22681 atcgacccta gtgaagtaca tttatttact caagacgtga tttgggagaa aaaagatacg
    22741 gctgtttatc gtcgattctt attgaaatcc gagatgaacc atgcggaacg taataatatt
    22801 ttagaaatca gagaaagaat gtatgaaaaa ggatggaaaa caggagaagt gatcggccag
    22861 tatctattga cgaatacgga tgaaaacaat atcagaactg aatattatca tgcatggata
    22921 gaaatgaaaa aataggaaat atgtgtttaa gataactcga aaatgatggt tgttttagtt
    22981 ataaagaaaa attttctggt tcgattacgg gtttaatgtg ggggattatt agtcgtggat
    23041 agatagaatt ttagtttttt agaggaaata tgtctttaaa aatggaatgg ttgcaattct
    23101 tagcgatata tacgatgtaa ttgtcctctt aaaaaagtat ggaaaaataa ttgtattggg
    23161 tgttatgtat aattcatggt gaactgagac taatgagaag aaaaattcat attgttatga
    23221 gtgagattgt atcagatgag aatgataaat taaataggtg cataaaagca ttacacttaa
    23281 aatacattgt tgcttacatt attacaatat gttaataagg caaaaataaa tagatggatt
    23341 gaataaacat attttttaat caaatagtcc ctactgtgac tt
//
LOCUS       DARBDN010000033        23065 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000033 DARBDN010000000
VERSION     DARBDN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.033"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(111..566)
                     /locus_tag="SCH06_001317"
     CDS             complement(111..566)
                     /locus_tag="SCH06_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077906.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(720..1928)
                     /locus_tag="SCH06_001318"
     CDS             complement(720..1928)
                     /locus_tag="SCH06_001318"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEG1077907.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNEGAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2040..2372)
                     /locus_tag="SCH06_001319"
     CDS             complement(2040..2372)
                     /locus_tag="SCH06_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEG1077908.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2520..3395
                     /locus_tag="SCH06_001320"
     CDS             2520..3395
                     /locus_tag="SCH06_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1077909.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3477..4058)
                     /locus_tag="SCH06_001321"
     CDS             complement(3477..4058)
                     /locus_tag="SCH06_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HEG1077910.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4064..5323)
                     /locus_tag="SCH06_001322"
     CDS             complement(4064..5323)
                     /locus_tag="SCH06_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEG1077911.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5325..6371)
                     /locus_tag="SCH06_001323"
     CDS             complement(5325..6371)
                     /locus_tag="SCH06_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077912.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(6606..6881)
                     /locus_tag="SCH06_001324"
     CDS             complement(6606..6881)
                     /locus_tag="SCH06_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEG1077913.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(7124..8434)
                     /gene="der"
                     /locus_tag="SCH06_001325"
     CDS             complement(7124..8434)
                     /gene="der"
                     /locus_tag="SCH06_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEG1077914.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(8616..9845)
                     /gene="rpsA"
                     /locus_tag="SCH06_001326"
     CDS             complement(8616..9845)
                     /gene="rpsA"
                     /locus_tag="SCH06_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEG1077915.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(9980..10660)
                     /locus_tag="SCH06_001327"
     CDS             complement(9980..10660)
                     /locus_tag="SCH06_001327"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEG1077916.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(10709..11344)
                     /locus_tag="SCH06_001328"
     CDS             complement(10709..11344)
                     /locus_tag="SCH06_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1077917.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(11410..12813)
                     /locus_tag="SCH06_001329"
     CDS             complement(11410..12813)
                     /locus_tag="SCH06_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HEG1077918.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(12800..13831)
                     /locus_tag="SCH06_001330"
     CDS             complement(12800..13831)
                     /locus_tag="SCH06_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077919.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            13862..14083
                     /locus_tag="SCH06_001331"
     CDS             13862..14083
                     /locus_tag="SCH06_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEG1077920.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(14248..14985)
                     /locus_tag="SCH06_001332"
     CDS             complement(14248..14985)
                     /locus_tag="SCH06_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEG1077921.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(15138..16478)
                     /locus_tag="SCH06_001333"
     CDS             complement(15138..16478)
                     /locus_tag="SCH06_001333"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HEG1077922.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(16715..18238)
                     /locus_tag="SCH06_001334"
     CDS             complement(16715..18238)
                     /locus_tag="SCH06_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEG1077923.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(18616..19227)
                     /locus_tag="SCH06_001335"
     CDS             complement(18616..19227)
                     /locus_tag="SCH06_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEG1077924.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(19350..19475)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(19557..20273)
                     /locus_tag="SCH06_001336"
     CDS             complement(19557..20273)
                     /locus_tag="SCH06_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEG1077925.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(20279..20848)
                     /gene="scpB"
                     /locus_tag="SCH06_001337"
     CDS             complement(20279..20848)
                     /gene="scpB"
                     /locus_tag="SCH06_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HEG1077926.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(20832..21629)
                     /locus_tag="SCH06_001338"
     CDS             complement(20832..21629)
                     /locus_tag="SCH06_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEG1077927.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(21599..21970)
                     /locus_tag="SCH06_001339"
     CDS             complement(21599..21970)
                     /locus_tag="SCH06_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEG1077928.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(21989..22876)
                     /gene="xerD"
                     /locus_tag="SCH06_001340"
     CDS             complement(21989..22876)
                     /gene="xerD"
                     /locus_tag="SCH06_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEG1077929.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         6468 a         4926 c         3910 g         7761 t
ORIGIN      
        1 aaaaatcttg tcacagtccc ttattctgaa taaacggtgt ggaagagaca gcctatcagt
       61 agtaataaga cacatctctt tcacagcctc atttttgcgt aaaaatcgat ttattcgaaa
      121 aattccccgt atacatcttc tacacgttga tctggattga tcacgatata caagttacct
      181 gttttttcgc tgatttttgt tgattgatat tgattgtcta atccttctgt tcctttatct
      241 agatatggga agtacacaag atcaggtgtg ccatttcggt aaaggatttc cattcgctcg
      301 atatcttcgt atttcaatgc gcgattaaac atgcccattt ccagtccgcc taggttgata
      361 tcatgtgtcg caactgcgtc cccttcatgg aagatttcga ttttaaatcc agcacacgga
      421 tggatttcaa caaattcact gccattgatt cgtccaaaac ttgttgtgat ttgtttgatc
      481 caaagatcgc cgatatgacg gcggttgatc gtccaggttt ctccatttct aaaataaaat
      541 tttagcgctg tcatttcttt actcattaaa aagactcctt tatgatgtaa tttattcttg
      601 tactacctca gtttagcaca aatttatgta agtggtcaca tcttatgttt tttcttctaa
      661 tgacgtatct gcccacttta agtagccaac aaagctgagc agatacagtc tagtgttttt
      721 taaatcaatt tttctttcga taaaaaatcc aaaacctgtt ttttatcatt ttttattctt
      781 tgttctacga cggctttttc agctaattgc aaagcttcac taacccactt accaggtttt
      841 tttccagttt cttctagcaa gattttacca tctactgcta attcgcttaa tgacttgata
      901 ggtaaacgat cataggattc tcctacggca tccatctgag gtgtttcgtc aaaatagatc
      961 atcaattctt ctacttgcag tgcatgtttt ttgcctaaga agtacaattc gaatggttcc
     1021 aaagctccag tttctcgttg tcgtagtcct tggacaagtg cttgaacgtc tttaatcatt
     1081 tggttagaac acttccacga tttcaaaaag gaacgaatct cattttcttt tagatccagt
     1141 tggctgatca ataatgccca tgcttggctc tcttctttca atgggacgga tggtaattca
     1201 gcaaaacgta aaagtgcttc gccttcttct ttcaaaccgg gacagcaaat gtagcactct
     1261 gtttcaataa atgcatggat tcccgcggcc ccttcatttc ccaagagcat cttgatgaat
     1321 tccacattta tacgttctac agatatttta cctaatagct cgtggttttc tttgatggcg
     1381 tagaaggttt cttcctctaa tttgaaccct agttgactga caaaacgcaa cccgcgcatc
     1441 attcgtaagg catcttcatg gaaccgctca tgaggattgc ctacagctcg caagatctgt
     1501 tcttctagat cttgcagacc atcgaacaaa tcgatgattt ctccatcttc tttcaaagca
     1561 aacgcattga tcgtaaaatc tcttcttttc aaatcttctg ccaacgaacg aacgaattcg
     1621 acatgatctg gtctacggta gtcctgataa gttgattccg tccgaaatgt ggtgatctca
     1681 tattgttcat cattttctaa taccaacaca gttccatgtt cgatcccaat atctatcgtt
     1741 tttggaaaaa gctgtttgat ttcttctgga aatgcgcttg ttgcgatatc cacatcatgg
     1801 attggctggt tcagcaagat atcacgaaca cttccaccta caaaataagc ttcatatcct
     1861 gcattctcta attttttcag aactggaatt gccttttggt attccagagg taattgtttt
     1921 aatttcattt ttccaacctt tcctgcgtgt ttcttgtcct gagataaaga ctcagttgca
     1981 tggtgactgt ttgacaagtc cgtttcagag tcttcaaggc caggaccact tcatcttgtt
     2041 tactcgtcct tacgctcaaa gcgattatgg tctctttgat tgaatttttc catgtttttt
     2101 tcaaaaactt cagttaagtc gatattcaat gaattagcca tgatcatcgt aacgaataaa
     2161 acatcaccaa gttcttctgc taccgagtta actggttcag aagccttttt gcttttttct
     2221 ccataagtgt ggttgacttc tcttgccaat tcacctactt cttcagttaa tcgagccatc
     2281 tgagctaatg gagagaaata ccccaccttg aattgctgga tatattcatc cacttcctgc
     2341 tgcatactgt ataaagaacg ctttttatcc atctttttcc ctccaaaact atcttaccaa
     2401 aactttaacg caaatcctag ataagagcaa ttgagaaaat cgaatttcca tgctacattt
     2461 aggaaggaat ttctaaatgg aaattctgtg aaaatacata attgaaagct ggaattcata
     2521 tggtcaaacg aaaaacagta aaagaagttc tttttatcat tataggaaca agtatttatg
     2581 catttggtct tgtttacttg aacatcgcta atcatttagc agaaggggga gtctcaggga
     2641 tcaccttgat cttaagagct ttatttggta ttgatccagc ttatacgact ttattaatca
     2701 acatcccatt gattttacta ggaggaaaga tcctcggtaa acgttccttg gcctatactg
     2761 ttctaggtac actttctttg tcattctttt tatggatctg gcaaagggtt ccactagaaa
     2821 tcaatttaca gcatgatcta ctgatcgttt ctctacttgc gggtttagtt gcaggtgtag
     2881 gaagcgggat cgtctaccgc atgggtggaa caacaggcgg cagtgatatt atcgctcgga
     2941 ttttagaaca aaattacggc atcactatgg ggcgttccct attggcattt gatatcatcg
     3001 tcttacttgc ttcattaacc tatatcgact tgaaacgtat gatgtatacg ttgattgttt
     3061 cgtatgtttt cagtcgtgtg attgattcga tcttagatgg cggatattct gcaaaaggtc
     3121 tacttgtcgt ctccaacaaa agcgaagaga ttgcaccact actgatgacc ggtctgcaaa
     3181 gaggtgtgac tttcctttct ggagaaggcg cattctctgg taattcaaaa aaaatcatct
     3241 atatggtcgt tagctctagt gaattaactg aagctaagag gatcgtccac gagattgacg
     3301 aaaaagcttt cctttcaatc atcaatgtgc atgaagtgga agggcaaggc tttacttatt
     3361 tgaagccaca gacaagatta ctgaaaaaac tataagaaaa aagacaaaga taggctatga
     3421 ggaaagattc cacatccagc tgacctttgt cttttttagt actatactat ttttaactaa
     3481 ttgttatgtt cacttacccg gttacttttc ttttgtgtct gcaaaaggat ctttcggtta
     3541 acttcatcag ataatttcaa aaaagcatcc ctatctccat cttctagtgc ttgatcgatt
     3601 tgagcataaa gcatttttag ttttgcctct tcttcttttt cttgaaaata tcgttcaatt
     3661 aattcagtat cttcttcact gactgaagaa tcccaagaag aaaatggatt gtcttctaag
     3721 atagatagat attctcttgt ctgccaagca ttttcgaata tacattccac atataaaggc
     3781 tttttccaat tcaaacggat ttcatgaaaa atctggtctg tgtccgtaaa ttcttttccc
     3841 tgcaaaaaca atttcatggg ttccccttca acagatagat cactgatctg cagtcctcga
     3901 tccgcaaaat tcgccccttc aacaaagtgg acattgctta aaatcgcttc atgattggca
     3961 agataattca agatccaaaa aacttctctt cggctaaaag atacatgatt gaccatccac
     4021 gttaaaaaat tcttcttttc ccgtacatca attagcattt ttctcacctc tctgttaggt
     4081 catctaataa tgacagtgcc tccatatctc ctggttcaag tgttaaataa taagtcaata
     4141 attcttgcgc tcttttcagc tgcccttctt ctcttaagaa aaaggcatac tctttcaaga
     4201 aatctggttc atgtgatagt tcatgataag cctgttcata gtgtacagct gcaacggtaa
     4261 agtcttctaa ttcattataa gcatgggcta ggttccattc tgcataagga ttagcagttt
     4321 cttccatctg attgatcact tgtatcacat cttcatatct ttcatcatcc aagtaaagat
     4381 tacttaaagt aagtaatgtt tcatcttgtt tgtctcctac ttctaaagct ttcagtaaaa
     4441 gttcttctgc tcgctgtcta tcatgcagac ggaaagcatt ttccgaggcc aggtgataaa
     4501 gttcgacttg gtaaggattt tctttgattc cttcttctaa cactgtttgt gcttcttcaa
     4561 tcatttcttc ttcttgaaga gcttgtccta gatatagata taacgattga taatgcggat
     4621 taacttctcg aagttcttcc agatagttga ttgcctgctg attttctttc aattgaagat
     4681 tcgtaaaagc tagctggaac agtcgatcat ctgtcctttc ttctttcagt gcttcttcta
     4741 aaggtacgat agctgcttcg aattctcctt gcatacttaa ggattgtcct aaacgttcct
     4801 gcatcgagat tcctgaaatt tcatttatcc cgcttgccaa caatgtttca taaaccactg
     4861 ctgcctcttt gaaacgatca actgaaaaat acaattcagc tagcgcaaac tggatcaatg
     4921 gttcatcagg aagcaaccca gctgcttctt tcaattttgc ttcactcact tcagggattc
     4981 cgataacttg gtacaaatca gctatcgcca ataagctttg cggatagtaa tcactttgct
     5041 tatccacttt ttccaggtat tcaaaagcta agtcgatctc attatcttcg attgcaattt
     5101 ctgctaacgg gatgttcagt ccgtcatttt ctgggtattg gttgatcagt tgttcaaaaa
     5161 tctgttttgc ttcgatcaaa aagccaatag ccagcaattc ttcgcctagt tcagctaata
     5221 tatctgctgg gtcttctttt aatgcttttt ctaaaaagat ttgtgcttgt gacaagtctt
     5281 catctgataa agcttgcaac attttttcgc tatttgtatt catttcaatt ccctcttatc
     5341 tcactgacga tttgttgaaa taccgtcatt gttctcaata attctttttc gtttggatgt
     5401 tggtatccgt ctattatacc tattttttct aaaacaagta tttttttgct tttttctgcc
     5461 aaaaaaagaa ctttttccaa atactccatc tttgaaatct gttccagcca gtggattgga
     5521 tagccaagca agtccagcca cacaaaaaag ttttttagtt ggaaatcaaa aggatatgct
     5581 tggagattcc acacgaaatg aaacatcatt cctaaaaatt ttttcatact agcagaaagt
     5641 agatggccat tttcggtcag ataaaaagct tgttcaaaca gtttaccata atttgacagg
     5701 ttttctgcct ctaattgata aaaatagatc atttcttcga tcatcccggc aaacggccga
     5761 gtcgttaatt gctttttatt tggatagttt ttatacagat tttgcaaaaa acgatgatca
     5821 caaatcattc cgcaacagat aaaagtcaaa aagtcaatct gctttccgtc cacctgccgc
     5881 tcgctgattg tttgatcata aacgatgcgt tctggcagat tgatggtttg cagcactaca
     5941 cgatttggta gctgcaaaat cgtccgctgc ggtgttaatg ctcggcttag agaacggatc
     6001 gatacaggga tcatccatag tgatgaatca agggttgtat gtttttgaaa aaaacctgcc
     6061 agatccatga tcccttcatt tccaaatccg atgataaaca tggattgatt ttcgggatag
     6121 cgtttgacga aatcaagcag gttctttaat tctgttaaat gattgcattg agtgttggca
     6181 caaatatacc agtcattgtt tgcttgattt gcaaataacg ggttgatctt atctgcaaac
     6241 aaatcataat agcgctgatt cgttaaaaat aagattggct gatcaatgga aagttctctt
     6301 agctgactga ctagcgtttc tccgtaaaac actttcgtca acgcatcttc tacttgataa
     6361 tcaagttcca tacgcatccc tcctcttctt atttttattt taccattagt aagcaaattc
     6421 tagaaaagat aagagcaaag ctcacctcat aacttggaaa taaataaaaa ttaaataaaa
     6481 tacatgtgtt ttctatgtat gacatacgga ttcggaatct ctgtctctta tttattcctt
     6541 ttctgctagg aaataaaaag aaaagcactt gtagccctag agccacaagc gctttttcaa
     6601 ctgtcttatt taacagcgtc ttttaatgct ttacctggtt tgaatgcagg tactttgcta
     6661 gctggaattt cgatttcttc accagtttgt gggttacgac ctttgcgagc tgcgcgttcg
     6721 cgaacttcaa agttaccaaa accgattaat tgaacttttt cgccgttagc taaagcatct
     6781 tgaatagttg aaaatacagc atctactgct gcagttgcat cttttttagt taaatcagta
     6841 gctgaagcaa ctttttcgat taattctgct ttgtttgcca tggatagatt cacctcctcc
     6901 acaagagata tgatagaaat atcatttagt taaaactttc tgagtggtcc agaagtttaa
     6961 aaagaaatat tgattaactt caatattctg ttatcacgat atcatatgaa ccgcttaata
     7021 gcaaggtttt taccaatttt cacatgcttt ttttagtcat agaaacgtaa caaacgaaac
     7081 tgtctttttc ttttgaaaaa aaaacgtcga tatggtaaaa tgcctatttt ctcctacgag
     7141 ggataattcg gatggacgtc ccttcaaaag taaatgcttt tctgatttga ttttctaaga
     7201 aacgttcata agaaaaatgc atcaattcct cttcattgac aaaaacgaca aatgtaggtg
     7261 gtttgacagc gacttgtgta gcataaaaaa tcttcaggcg ttttccttta tctgttggtg
     7321 ttggattgat tgctacagca tccataatga tatcattcaa cacagccgaa gagatacgaa
     7381 gattctggtt catacttact tgttcgatca tttcaggcag acgttccaac cgttgtttag
     7441 tcactgcaga aacaaaaacg attggagcgt aatcaagata ccggaattca tcacgaatct
     7501 cttgttcgaa atcacgcatt gtattggttt ctttctttac aagatcccat ttattcacga
     7561 cgataataat tccacgacca gcttcatggg cgtaacccgc tactcgcttg tcttgttccc
     7621 gaatcccttc ttcagcattc agtaccatca aaacgatatc agaacggtca atggcacgca
     7681 ttgcacgcat cacgctgtat ttttcagtat tttcgtatac ttttccgcgt ttacgcatac
     7741 cagctgtatc tatcattaag aatttctgac cactttcaga aacgaagtgg gtgtcgattg
     7801 cgtctcgggt cgttccttca atatccgaaa caattacacg ttcttctcct aaaatcgcat
     7861 tgatcaaaga ggatttacca acatttgggc gaccaatcaa actaaactta atcgtgtcgt
     7921 cgtcctcttc ttcagtctct tcagagaaat acttcactgc ttcatctaaa atatcaccaa
     7981 tccctagtcc atggcttcct gaaacaggat aaggatcgcc tagccctaag gaataaaatt
     8041 catagatatc gtttctcatt tctggattat ctactttatt gactgctaaa atcactggtt
     8101 tattacttct gtataaaatt ttcgcaacca tctcatctgc gtctgtcacg ccttcgcgtc
     8161 cgctgactac acaaatgatt acatctgctt cttcaatcgc gatttctgct tgatgcttga
     8221 tctgatccat aaaaggttca tcgccaagat caattccgcc tgtgtcgatc acgctgaatt
     8281 ctcgacctaa ccattcacct tttgcataaa tacgatcacg agttactcca ggagtatctt
     8341 cgacaatcga gatacgctca ccagcgatgc ggttaaaaat cgtagactta ccgacgttcg
     8401 ggcggccaac gattgcaatt gttggatttg ccatattatt tcctcctcac aagtttccaa
     8461 tctcacttag tttaacgaat gcattgccaa ctttcaagca tagattgtca attaaacgaa
     8521 gtatttttat tccttattga aatactaatc gcttttcaaa agaaaaactg agacaaaagc
     8581 agctgctttc atctcagtca cagatacaaa atcaattatt tttcagaatc atcggttgct
     8641 ttttcttcta cttcttcttt caacgcatca cctaaaatgt ctcccatagt aaatccagta
     8701 ttttcttctg gtaattcata agactcaaca ttttttggtt cttcttctga agctggtttt
     8761 tcttctaaag ctttgatact caatgcaata cgatgttctt ctggatggat ctctaatact
     8821 ttcactttca cttcgtcacc ttcatgaagc acttcatgtg gtgtcgcaat atgtttatgt
     8881 gaaatttgag agatatggac tagcccttct actccaggga acacttcaac aaaggcaccg
     8941 aagcttgtca aacgtttaac tgttccgtct aatactgtgc caactggagc ttttgtatcg
     9001 atttctgacc aaggtccagg ctgtgtgtct ttgattgaca aggaaacacg ttcttgttca
     9061 ggattgatag acaacacttt gacatttaca tcatcattga cagccaatac atcacttggt
     9121 tttgctacat gactatgtga aatctctgag acatggacta gaccgtcaat tccgcctagg
     9181 tcgacaaatg cgccaaaatc agtaagacgt gcaacacgtc cactgagaac atctccctca
     9241 tggatagttg aaagaatttc ttttttcttt tcttctcttt cgttttccac taccgcttta
     9301 tgcgataaga tcaaacgatt ttctgatggt tcgatttcga tgattttaaa gctcaatgtt
     9361 ttgcctttat agtctgaaaa gtctgcaaca aaatgatctt ccaccattga tgcagggaca
     9421 aaaccacgta caccgacgtc aacgactaaa ccgcctttga caacatttgt aacaggtgct
     9481 tcgatgacct tgccctcttg gaaatctctt tcgatatctt cccaaacttt tttagcatct
     9541 aaacggcgtt ttgaaagtag gtagctgccg ttttctttat ctttgccgat cgtactgata
     9601 acgactaaat ctaatacatc accgactttt actacttcgc tgatatcttc taccggcaaa
     9661 gttgataatt cttttgccgg aacgactcct tcaactccag ccccttcgat tccgacaatc
     9721 acttgtttgt cttcaatgac taaaacttcg cccttaacaa catcgccaac ttttacttct
     9781 tgtacgcttt tcattgcgtc ttccattgac tggttgttct cttgattttg atcaaattct
     9841 gtcataacac ttgtcctcct aaccaacatt ctgccgtaag tacggtactg tttttagttt
     9901 aattgattat tcaaaaaaaa taaagcgatt tcgttcgttt tccttgaaaa aacaattgtt
     9961 tttcattttt tttcttaatt taaaaaagaa gataaccttt tttcaaaaca acagctttta
    10021 ttgctgcaac gacttctgga atcgatttgc cagtcgtatc gatacgaaca gcatcctctg
    10081 cttgcttcag cggagagacg tcccttgttg aatcataatg gtctctttcc tgtatctctt
    10141 tcgtcagtgt ttcaagatca gtcggaattc ctttttcttg gttctctttg aaacgtcttt
    10201 ctgcacgctc acttacgctt gctactaaaa agattttcac ttctgcattc ggtaatacag
    10261 ctgtcccgat gtctcttccg tccatgacaa cgccaccgcg ttcccctatt tttcgttgga
    10321 cagcaactaa ttcttctctg acttttccat gtgcagagac ttcagaaaca gcttttgtga
    10381 catctggttg acggatttct aaagtcacat cttttgatgc tatgaataca tgctgtccat
    10441 cttcttgttg cgaaaaagag ataggatact ttttgatcag cgaaactagc ccttcttcat
    10501 ctgaaaaaga tacattgttc gtaatagcta aataagttac tgcgcgatac atggcaccgg
    10561 tatctgtata aatataattc aattcttttg ctaatatctt ggcaacggta cttttcccag
    10621 atgaagcagg cccgtcgatt gcaatactga tttgtgtcat gatataactc ctttttctca
    10681 gaaaaaaagc cgcaaagcgc ggctattatt atttaattct taattcttga ccagggtaaa
    10741 gcataaagtt gtttggatct aagccattca attcaaacaa ttgatcagtg gtgatccctg
    10801 cacgctcagc cacttgtttt ggaccttcgc ctgcttgaac agtcgttgtt gaaccggctg
    10861 cagctgatga agaaggtgtt gtttctgctg cattgctgct tgaatcccct gcttgataag
    10921 ttgcctcact tgaggaagtc ggtgttgtct ctgctgcaat actgctttct gacgttacac
    10981 ctgtatcttg agacacagta gattcttccg cgattgtact agattctact gttgaagtct
    11041 cagttgactc ctcttttgtt gtacttgtag aactttctac tactgatgtc gaagtttcag
    11101 aagaagttgc tgctgttgca ttgttgcttg atccatttct gatccagaaa taagcacctg
    11161 ctggaatagc gatacataag accagtaaaa tcaaaaatag cgaaagaaat aatgtatttc
    11221 ctttcttttg ttgtctctga gaacttcttg atgaaacttc atcatctgta tcgtagattg
    11281 gttgttccca tggttcttgt gtttcgttat tttctgtaga ttgatgtcta tcttttctgc
    11341 tcactgtttt acctcctaaa ctctatcgtg tgtattatac cataggaaaa agtgtcttgt
    11401 cctaaaaaat caatgttcca tgtttttttt aaataaattt agtaaaatcg tttcccaatg
    11461 aagttgttca gtcttagaaa aaagcttcct ctttggcaga agttctgctt ttgctccatc
    11521 aatatcacaa caattctgcg gcttttcgga gagtttttcg ccaaaataag ctaagatgaa
    11581 ttttctgcgg cagttttctt cattaatata gcgaagcatc tgctgcaggc ggaattcttt
    11641 ttctttttcc tgacgtttga gccgttccac ccaattttct ggtttttcag actgctggat
    11701 cagctccatc catttttttt gcagctcatc aaagggagct tgctttgtgg catattccaa
    11761 ataaagctca aaactttgtc gctgttctct agaaagttga ttaaagaaat aatggatacg
    11821 ttcatcccca ctttgataaa aaagaattgc tgcactttct tcctgatctc tgcctgctcg
    11881 accgatttct tgtacatagt tttctagact gtctggcaaa tcataatgga ccacataacg
    11941 gatatcagat ttatcgatcc ccataccaaa tgcattcgta gcaatgagaa actgcagctg
    12001 attttttaca aactgctgtt gaagttgtct tctttgagct gcatcaagac caccgtgata
    12061 gtatccaact gtaaaacgtt ccctgaataa atgatacaat cgttcgactt ctttttttgt
    12121 tgcacaataa atgattgccg ctccttgtgc tctttccatg aagtgttcaa gttcttgttc
    12181 tttttgctgc gttttccgaa caaaaagcga gatattttgc cgattgactg attgtctgat
    12241 ctcttttggt ggtcgatcaa atagtacatg acgtatatct cttgctacta aatctgttgc
    12301 tgtcgccgtt agtgccagtg tgaccgggtt tcctaaaagc tttcggattt ttcctaactg
    12361 ttgatattct ggacggaaat caactcccca ttgagacacg caatgagcct catctactac
    12421 atataacgca atattttgtt ttttcagatg ctctaaaaga gaaggattag tcaacatttc
    12481 gggactcaaa aacaaaaatt tatattgcga tagatgacgg aggacgtatc ttctttcaga
    12541 ttgcgaaagt aaactattga aagcagctac tcgtttctcc cctcgttttt gtaattgcgt
    12601 cacttgatct tccattagag aaagcagcgg tgacacgatg atgaccagac cttccattaa
    12661 ataccccgtc aattgatagc aaaggctttt tcccgttcct gtaggcaaaa tagcgagagt
    12721 atcttctcca tcaagcaacg cctgaataat ttcttcttgg ccgggacgaa atgaatcaaa
    12781 tccaaaatat ttttttaatt catttattaa cattctgtat cgcttccttt ctcaatagat
    12841 agatttgata caaacgaaat tctccataat ctaattgtcc atctacattc cattcgctaa
    12901 agcgccactc tcgcacggaa tccttatttg gttccaaacg ttcgattgtt tctgcagaga
    12961 gaatccactc gtatggaaaa tcatcaaaaa acaaggccca ctcaataaga tgatctgtta
    13021 ctgttcctct ttttaaatga cggattgcca tgatctggtc aattgtctga ccattcataa
    13081 acatctgctt ggtgatcatc atgctttgat tgaaattttg ctgtaataat gaatcgatca
    13141 aagcgtgcca aagcgaatct ggccgttttt cgatttgtgc taacaaaagg tggatacatc
    13201 tgctttgttg cagataaacc tctgactcat cattgttttt tgccagctga taaggaagca
    13261 gccctgttcg ctcatttcca gataattggt tagctaaaaa atctgctgct tcttctggta
    13321 tctccgaaaa cagctgcacc aaactctcat acgcagtatc aatcaaaatt tcacgtggca
    13381 attggctttc actaagccat ttttttagtt ggaaagtata aaaaggactt gtctctgctg
    13441 gaagatagtc ttgaataccc gttgccagat tagaaattac ttgaacagca aatttaatga
    13501 gccgccaact agtttcccct gttctgccat agcggtcaaa acgcaaacca gtatgttcta
    13561 tttgatgttc ggacaacata tcagcccctg caggcgttag ctttgcttca ttttcattta
    13621 tttcgatcca accttgctgc gcaatttttt gcaaaatttg ataaaactta tcctgcttca
    13681 attctggaaa actgttatgg ataaacaaaa gttcgtgggt aaatccataa ataagtactg
    13741 aagtcgttcg ttttcccaca aggagttggt aaagagaact aatccgcagc ttgtgtcctg
    13801 atgaaaatag cgataaaata aaaacaatca tattattctc cttaagttag gatggttaga
    13861 aatgtcacta ctatgtaaac ttgtacctga acgctgtatt gcatgcggtc tttgtcaaat
    13921 cgaagcgcca gatattttcg attatgatga agaaggaatc gttttatttg cccaagaacc
    13981 agaggctcat caacagttcg tgatgccgga agaagaaaca tatgtaaaaa aagcgtatca
    14041 aaaatgtcca gttcgagcga ttttattaga aaataaaata taaatataaa cgaaacttta
    14101 aaaacgtaca ctaagttctc taaacttgaa aataagccgg gatctgtttc tcttgttccg
    14161 tgaaatcccg acttattttg aaagattcat ttgctatcta tagttaattg actagttttt
    14221 tcacggaccc tataggaccc atttatatta tttcaacttt ttcagccagt tttccaatgt
    14281 attgacgatc acagtttgct ggtctgcgtt agaaatttct gcctctccat ctcctttttg
    14341 ctcaccatag ctgccaaaac ctccatgatt tccgccattg attgatacat actctgttct
    14401 ttccggtaaa tactgcttag cttcttgata agcttcctga ttcaatactt tatcttttgt
    14461 cgccgtgatc gataaaacag gaacagctga ttctgtcaat gttccttttt tgtcgggata
    14521 acttgccatg aagaataccc cttttaaatg tttgtctgaa tgattcttat tgacataacg
    14581 acttgccatt acgccaccta atgaatggcc accgatcaca taatcggaat ttggaaaatc
    14641 ttctttgacc ttatccgctt tgtttccgcc catcactgct agatcaagtg gcattttgac
    14701 aatagcgact gaaaagccgt tttttgctaa atcttgcgcc caaatactat aactttctgg
    14761 ctctacgaga gcaccaggat aaaaaataag taatggagac tttccatgat tctttttctc
    14821 tccttcaaaa aataagtaat cttctttgtt ttttccttct tttaccaaca cttgcgcttc
    14881 tgacgatggt tcgtacgtat tttgctgtat atagtaataa ccggctccac cgagtaatcc
    14941 taaaatgatg actaagccaa ttagtattcg tctaaatatt ttcactttct cccacctttt
    15001 ctatctgagt gacccctttt tcttaatcaa gtatgattat accttaaaaa aataagagag
    15061 aaatgcaaac tttccagcat caaataaaaa aagacggaat atccatttga atatccgccc
    15121 tttttgtatg tttattttta tttagcacat aaacgataca cagcttctgc ataaatttcc
    15181 attgctttat acatactact taattcccat cgttcattcg cctggtgcat aaagtcagga
    15241 gtatcaggga acatcgcacc gaatgccaca cactggttca tcgtacgagc aaaagtagcg
    15301 ccgcctgata caaacggttc agtcatgtct ccagtaatat cgcgatatgt ccccaataga
    15361 tttttcacta actcactgtc tagtggcacg tataatgaat caaggaagtc aaattcttca
    15421 taagtcaacc catatttttc tgctgtttta gttaatttag ctactaaatc atctttcttg
    15481 aatgtaacag ggattctcat atctacaccg atttttgttt gttctggtgt gatttccaaa
    15541 cttgcaaagt tcatcgttag ctcgccggat tgttcatctt ctgttttgcc cacgacagct
    15601 tcaccagttg cattttcttg aactaatttt cctaagaaat tgattgggcc aaaatcaaat
    15661 acttctgaaa gagcaattgc cagacgagaa atagcattca ctccttgtgc tgcatctttc
    15721 gcgtggatac ttttaccaag aacgacgatg ccttcacctt gttcttcgaa atcgaattcg
    15781 tgttttttca atgcttcttt tacttcagaa agcttttctc cagagtaagg agctgcatca
    15841 ggaacaacat tcaacgctcc tccagctttt acagaaaact cgttcgttcc tggtcctgtc
    15901 aagtaagctt gcaataagcc tttttctgca taaattaaag gaaattcagc atctggcgca
    15961 aatccttgcg taattccttc ttctttttcg ttatattttt ctaaacaacg ccataaattt
    16021 tcttcatctg taccaaagat aaaacgaata cgtgtcttga attccacgcc agcatcaatc
    16081 aaagctttga cggcatacat tgccgcaata gaaggacctt tgtcatcttg ggatccgcga
    16141 ccaactaacc agccgtcttt tatagttgga tcgaatggtt ttgtttccca attattttcg
    16201 tcccctgctg gaacaacgtc catatgacac aagataccga ataattcatc tccagagcca
    16261 atctctgaat aaccgtaata gccttctgga tctttaaatg ttctaaatcc tagcttttca
    16321 ctgatttcca atactttatc caaagcttca atcacttttt taccgaaggg atgtccttgt
    16381 cctgaatctg cttcatctag tacggaagga attcggatca attcgctcaa tgattctaat
    16441 gcttgttcat gatgttgttc tgtcacaaat tttttcatga tattatcctc ctaatatgtt
    16501 aaaaagggtc atgtcaaatt cctccgacac aacctcttct tctcaaataa tgacgtttta
    16561 agcctgctcc atcagcaagc agaatgttct taacaaatga tgaaagaaaa aacactcact
    16621 gaatggagct attgacttgt ccacgtgctt atcgatagcc gtttatcggt ttcttcattc
    16681 ttatgataga ccttgtacct gtatttgtct aggtttagaa cattgctgct acacctagga
    16741 tcacacagat ggctacaaat aatatcgcaa ttaatttacc ggtaaatttc caccacactg
    16801 aaacatcgaa acgagcaatt gctacagcac ccattacgat agcagatgtt ggtgtaatta
    16861 agtttactaa accagatgca gattgataag cagtgattac taaatcctta ccgacgccgg
    16921 caaattcacc cataggtccc atgattccca ttgttgcagc agctaagccg gaagttgaag
    16981 gaatcaagaa tgacataggg atatagaaaa taaatgtaat aatgatgaat acacttgaag
    17041 ataatgaact taatccttgt tcgccccaat gtaagatggt gtctgtgatt aatccattgt
    17101 tcataaccac ttggatacca cgagcaacag ctactacgat tgctacaccg atcaaatcag
    17161 aagcaccagc taaaaattca gagacaaatt cagactcttt catgccataa gtgattgcta
    17221 ctacgatgga cattactaag aataacatag taatttctgg gaagtaccag tcacctaatg
    17281 gaagcatgct tttacctaga accgtaccta gtaccggaag gtttgttaac cagtttgtca
    17341 atgattcaaa aatcgtgaaa ttcgcattca aggttgtcca aggaatcaaa ctgatgatca
    17401 tgataccaaa agtaataaag aacaatacat taacatgttt ttgttttttc gtgattactt
    17461 cttgacgacc gattgcttca atatcgaaat gcttcatatc ttctttacgt tggttgtata
    17521 ctaatgattt tgttggatct ttttcgatct ttgatgcata acgatacaca tatacaatag
    17581 aaatagctaa caaaataacg aacatcaaga atcgaagacc aataccttca cccatcgaaa
    17641 tcccaacagc ttgtgaagct acgcctgttg caaaaggatt taccgttgaa gctagacagc
    17701 ctacttgaga ccctactaat acgattgcta cagctactac tgtatcaaag cctacagcca
    17761 tcatgactgg gatcagtaaa gcatagaatg gaatcgtttc ttctgccatt ccgtaagtag
    17821 agccgcctaa tgcaaataac agcatcaata ctggaataag cattttttct tttcctttga
    17881 atttcttcac aactgaagca atcccggcat ctagtgcccc tgttttgttg ataataccta
    17941 aaaatccacc aacaaccaaa atgaagaaag agattgggat tgcagcaggt gtttctttag
    18001 ttagctcccc cgctggtaca cctagcatcc cattgattgg cgccatgaaa atatcccaca
    18061 gcccttgagg attttgttgt actcgttcat atgatccagc gacgatgttg cctgcatcgt
    18121 ctacactata gtgcccagct ggtataaacc aagtaagtac agcgattact gcaataataa
    18181 taaataagac cgtatacgct gaaggcattt gaaatttttt cttttttgtt tgttccatct
    18241 tcttcttcct ttcttttccg ttagagacaa caattttggc tctaatgtta ttttatcaaa
    18301 aagagtatca gaacaaaaat aataacacgc attttgtaaa acttttgttc aaaaagttcg
    18361 tttttcccta ttccctcctc ttttttcagt tttttaaagc tttcttcttt ttcattgtag
    18421 cgtttccttt tttttataaa caaacatttt cgtcttttaa aaggagaaga atttcacatt
    18481 tgcaaagaat tgattgattt ttatgcataa atcaaaaaaa tactcaaaac aaacaaataa
    18541 aacgtttaca ttattgcatg tcttgtattt ttttccaaaa aaaaagacca agaaatttct
    18601 tgatcttttt gatatttatt tgactgctgt atgacgttgt tcgaactgat gttgttttcg
    18661 acttaaccat ggaagaagtt gcgcatgcag cactaaaaag acagcactca cgatgaatcc
    18721 tttgatcaag ttgaaaggaa cgatcccaat cagtacatag tttgctaaag acatgcccag
    18781 catctgtgtt gcgttcagcc ctaaaaacat taagtaaaga ggcgtaataa cgaaataatt
    18841 tgcgatactc ataaaaatag ttagagcgat ggttcctgta atgacaccta aaaatttgtt
    18901 tcttccttta tgctgtttct ttacactaaa gaaataataa atcgggaatg taaagatcgt
    18961 tgttgataag aaactagcag tgtctcctac caaattatcc ggagaaaaac ctgtagtcag
    19021 cagatgtaat actgaacgca agaacgctgt tgcaactccg gccgctggac cgaataagaa
    19081 catgctgatc aataccgaga tatcactaaa atcgatcttc aaaaaactaa aagccggcat
    19141 gatcggaaaa gcaaaatact gtaaaactaa tgcgatcgca gcaaacatcg ctactgcaac
    19201 cattttctgt acacgggtgt tcttcatttg aaatcctcct gttaggactc ctcttcagcg
    19261 aactttttga cgtttctctc caaatgaaaa aactctattt tccagggaaa atagagttag
    19321 agttatttga tcaagcgtcg tcaaataagc tctatcttct ttatccagac tatactgtcg
    19381 gtatcggaat ttcaccgatt cagctatttt tttgcaaaat aggtcgtgga ctataaccac
    19441 cggtcgggaa tttcaccctg cccctgaaga cgaaccttat ataatttttg tttacatatt
    19501 cattatacat atctattcaa aaaacgcaac atctaacaat tataaaaagt aagtgttcat
    19561 tttgagtggt tcagcaaact gctgacttct tttttgttca gttcacggta atccccagga
    19621 cgtaggcctt gtaaagtcag atctccgtat ttttcacgtt ttagtttttg cacaggaaga
    19681 ccaactgctt gaagcatatt tttcacttga tgattacgtc cttcgtggat cgtcaattcc
    19741 acgatactgt ggtttgtctt aggatccact gataaaattt ggaatttagc tggagatgtt
    19801 tttcgtcctt cgatctttat tccttttgtc aaaggtgcaa gcatcgattt tgtagcgatc
    19861 ccttttacct ttgcaacgta aactttatcc acttcatgtt ttggatgtgt caggcgctga
    19921 gcaaaatctc catcatttgt cagtagcaag atccccgaag tatcgtaatc cagtcgacct
    19981 acaggataga tacgttcttt taccatcggc aaaagatccg taacaacttt tcttcctttg
    20041 tcatctgcaa cagcagaaat aactccttta ggtttgtaca ataaatagta accgtattct
    20101 tcttgataaa ttgggacttc atccacttcc acagtgtcat gtttcccaac ttttatccct
    20161 aattccctta caacttgtcc gtttactttt acacgtcctg caaggatgaa ttcttctgct
    20221 tttcgacgag aagtgatgcc agcgtgggca attactttct gcaatctctc cattacaatt
    20281 attctccttt attcattcca tcaaagaata gatctggtga cacgtcttct tcaagtgaaa
    20341 tttccatttc ttgtgtatca ggcagttctt ctaatgattt caaaccaaaa taatctaaga
    20401 agtagccagt tgttccatat aatatcggcc gacctggtcc ttctactcta cctttttctt
    20461 caatcagttt atgggcagct agacgctgta ccgctcctga aacctgaact cctcgaatct
    20521 gctcgatttc agctcttgtg attggctgtt tataagcgat gattgctaag gtttcgacgg
    20581 cggcttgaga taatgtgttt gatgtccctt gcgcatatcg cttaagtaag ggagccagct
    20641 cttttttagt cgttaataca taatggcttt ccgtttcaaa aatatgcaaa gctgagtgcg
    20701 agttttgagt gtaagattct tttaattctt tcactaaact tgtgacttct gcttcgctga
    20761 gatttaacag tccgcttaat tcttcattac tgatcccttc ctcgccaaca ataaaaagaa
    20821 gggcttcaag ttcacttaat ttcgtcatgt tcggtatctc ctactgctgg ataaagcata
    20881 attgattcat agttttcttt ttgttgcgca atgatctgcc cttttttcat caattctagc
    20941 aaagccataa aagtagtgac aacttcactt ttagaaggtg actcaaaaaa agaatcgaaa
    21001 gtacagccat gcgcatttct ttttatacgc tcttcgataa ataccattcg ttcttcgatc
    21061 gttgtgtcat cgggcgtgat cgttttttcc actttttgag aaaatttctt acgttctaag
    21121 attttctgca tggcacggat caaatcgatt tttttgactt gtcctcgctt caacggcttt
    21181 tcagcatccg ctaacccatc gatgttcata ggttcttttg tgtaataaag acttcgttcc
    21241 tctgcttttt ctgtcagtct ttcagctgca tatttatatt tacggtattc taaaagctga
    21301 gtgaccaatt cttctcgagg atcttcttcc cataattctt catcgtctgt gccgaattct
    21361 tggacaggaa gcaatgtctt gcttttgatt gccatcaatg tagcagccat cactaagtat
    21421 tctcctgcaa cagctagctc gagtgttttc attgtatgga tataattcat atattgctcc
    21481 gtgatcgtag cgatcggtat atcatatata tcgatttcca tttgctgaat cagatgaagc
    21541 agcagatcga gaggaccctc gaatacatct aatttaatat tgatctccgt caactcattc
    21601 actctttctt ctttttcttt gctagccatt ttccaatgta aggctctgtg atttcagttg
    21661 cacggatgga gacatccggg tacttttcct gtaattcatc taacatttga aagcccatat
    21721 tctcaccgcg ataagacgga ttcaaagaaa tgtcatggat gatcagctga tcgttcgttg
    21781 cccagtaaat accaataatc ccttgaatgt tggttgaacc ttctggcgta aagaaaaaaa
    21841 gttcataatc gtcttcagat tcgtacgtat caatctcctt caacaaagaa gttttacctg
    21901 tcagtttctt atggaaactc aatagtccca tagcaatttt acggttttct ttccggtaat
    21961 gtgttaacat cttctcacct tcctatgact aagcccttgg aaaatgctgc ttataaacat
    22021 ccgtcattct tttcttcgtg atatgtgtat aaatctgagt cgtagagata tccgcgtgac
    22081 ctaacaattc ctgtactgtc cgcaaatcag ctccattttc tagcagatgt gtggcaaagc
    22141 tatgccgcag cgtatgtggt gttacttctt tgtaaatccc agcctctcgt actaactgct
    22201 tcagattttt ccagattcct tgccgagaaa gacctttccc atgattattg acaaatacat
    22261 gcatttcaga tgcgtccttt acaagtaatg gacgtgcttc gtctaagtag cgttccagcc
    22321 attggatcgc ataatcacct aaaggaatga tccgctcttt atctcctttt ccaactgtct
    22381 gtaccagtcc aagagaaaga tgaagatctc ccaatttcaa tccaatcaat tcactgacgc
    22441 gcatcccagt agcatacatg acttccaaga ttgcacgatc tcttatccct aacgtttttg
    22501 tcgtatcagg tgcttcaatc agcttttcta cttctgtcag agtcaatgta cttggtaatt
    22561 tctgtgcttt cttcggcgta tcgatatgtt gcatcggatc atgatcagtg atacgctctt
    22621 gccgtaaaaa ctgatggaat cttctgagac ttgagatcat ccgagtaaca gttgctgtcg
    22681 cttttttttc ttcatgcaac ttctccagaa aacggatgac taaaaagcga tcgacatcct
    22741 gccatgaagc aattttctgc tcctgtagaa aatgcaagta ctgttccaaa tcacgttcat
    22801 agctttgtcg tgtattggcg gacaatcccc gttcaatatt caagtagtgg agataatcgt
    22861 tgatttgctc tttcataata atccccctca tgcctctcta tcatatcaga taccgcttca
    22921 ttctgatagt ctttttccat aatctgagca aagaaaaagc cgtctagaca ctcagacgga
    22981 ctggtttctt ttttcggctc tataatttat gggactgatg aatcagaatt gattcttcag
    23041 ccccattttc attttaggta ttaaa
//
LOCUS       DARBDN010000034        22839 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000034 DARBDN010000000
VERSION     DARBDN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.034"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..554
                     /locus_tag="SCH06_001341"
     CDS             <1..554
                     /locus_tag="SCH06_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077930.1"
                     /translation="VLMNFINPILMLVLVSPVSLIFSKKYGKKELASVGMFFSAIVYL
                     LLFLIKPSNMYVFLVLTSVGYMGLGIFNTVIWANITDVIDDQEVKSGQREDGTIYAVY
                     SFARKIGQALAGGVGGWTLSIIGYDSLAKVQSGEVLQKLYNSSTLIPAVCFFVVGLIL
                     FFVYPLSKEKVLENYNLLNQKHN"
     gene            565..1359
                     /locus_tag="SCH06_001342"
     CDS             565..1359
                     /locus_tag="SCH06_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEG1077931.1"
                     /translation="MNSWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVPSINRLKHWVSVTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNRQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAIQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDILFKCLSGEYIDIEQKYIDTFWKNLTNK"
     gene            1372..3138
                     /locus_tag="SCH06_001343"
     CDS             1372..3138
                     /locus_tag="SCH06_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEG1077932.1"
                     /translation="MTIKVDLRKKPYHLDEDAISWIEETIDAMTLEEKIGQLFVNMGS
                     SRDKNYLSSMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQSPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLSTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNLDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYYKG
                     IISEERLRDALRRILGLKAKLGLHKKEKNKILLPKQEAMEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKDLTEKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGISPIDAYCGLKDTFI"
     gene            3166..4974
                     /gene="uidA"
                     /locus_tag="SCH06_001344"
     CDS             3166..4974
                     /gene="uidA"
                     /locus_tag="SCH06_001344"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEG1077933.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPMVEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVILPKKLLEERLVLRFGSATHEAKVFLNG
                     KLINQHKGGFTPFESEINQFIKDGSNRITVAVNNVIDDSTLPVGILKETIQEDGDIKK
                     ENLVNFDFFNYAGINRPVKLYTTPKDYIKDVTINTKIIDSDANVEFNIDTEWTGEILI
                     AIYDEEAQLIAEAKGKEGVIQLKNPTLWEPLNAYLYSMKVSLINENKVIDTYTEEFGI
                     RSIQVSNGKFLINNKPFYFKGFGKHEDTYINGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHDTWKEIRTENAHKM
                     AIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLKHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGLHDTVPTMFTEEYQVGYYEANHEVIDKCDNFVGEQVWNFADFETSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLKKRWSSIPNFSYKK"
     gene            5146..5547
                     /locus_tag="SCH06_001345"
     CDS             5146..5547
                     /locus_tag="SCH06_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEG1077934.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNETKSIRKRNINITDNEEPLT
                     NSNEGKYSQTHFDEQDVYFLFGMEILISDQKLSAAIDHLSEIRRKVILLYYFAGFNDT
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            5541..5786
                     /locus_tag="SCH06_001346"
     CDS             5541..5786
                     /locus_tag="SCH06_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077935.1"
                     /translation="MVDNPKKRQYPLVPLSIIQSALEEDPISIKMILKHYHSYIAKLC
                     LTNGFNEAGQFITYVDEYMLRQLEIKLIEAILKFKIN"
     gene            complement(6110..6331)
                     /locus_tag="SCH06_001347"
     CDS             complement(6110..6331)
                     /locus_tag="SCH06_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077936.1"
                     /translation="MRNEIANITIIRETLQNHTANEISKHTGLNLSTIKKLKSGERSI
                     EKLNLHDAICLTEFGLKNNRKNVEINIWK"
     gene            complement(6493..6565)
                     /locus_tag="SCH06_001348"
     tRNA            complement(6493..6565)
                     /locus_tag="SCH06_001348"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6530..6532),aa:Lys,seq:ctt)
     gene            6641..6871
                     /locus_tag="SCH06_001349"
     CDS             6641..6871
                     /locus_tag="SCH06_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077937.1"
                     /translation="MDFQDYEKIFESYPSILKITDLTKMLNIGKNKAYNLLKDRSIEN
                     IKIGARYKIPKKAVIEYILKIQDEGKNHAIIK"
     gene            6915..8084
                     /locus_tag="SCH06_001350"
     CDS             6915..8084
                     /locus_tag="SCH06_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1077938.1"
                     /translation="MKLRANIIEKRGTLQVVVSYKDSNGKIRQKWKDTKLKKKGNKKR
                     AEKIRDEFLLELESQLAMECECANPNLLFYDYLLNYLEVSKKQVAFNTYVGYKHYVHN
                     RIYKFFYPKKIKLNRLKPYHLQEFYQYMLNDNCTANTVIHYHAFIRKALQEAVITELI
                     STNVADKVRKPKKKQFVSQVYNQQEILKLLDILSEEKLYLVVLLTAFYGLRRSEVLGL
                     KWSAIDFLNKKIMINHVIIENPENMSQLIKKDQTKNSSSYRTLPLVETIERALVNQAK
                     WQQDNRILLGDDYILEDNEYVFTMEDGRLMKPQYVTHRLSKLIKKNGLKKIRFHDLRH
                     SNASIMLDSGQNMKSIQEWLGHASYSTTANLYTHLTAGVKDRAAEALENAFGFKE"
     gene            8658..9227
                     /locus_tag="SCH06_001351"
     CDS             8658..9227
                     /locus_tag="SCH06_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEG1077939.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            9214..10074
                     /locus_tag="SCH06_001352"
     CDS             9214..10074
                     /locus_tag="SCH06_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEG1077940.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            10264..10968
                     /locus_tag="SCH06_001353"
     CDS             10264..10968
                     /locus_tag="SCH06_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1077941.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            10973..12808
                     /gene="walK"
                     /locus_tag="SCH06_001354"
     CDS             10973..12808
                     /gene="walK"
                     /locus_tag="SCH06_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HEG1077942.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            12805..14121
                     /locus_tag="SCH06_001355"
     CDS             12805..14121
                     /locus_tag="SCH06_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077943.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            14122..14991
                     /locus_tag="SCH06_001356"
     CDS             14122..14991
                     /locus_tag="SCH06_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HEG1077944.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            15046..15855
                     /locus_tag="SCH06_001357"
     CDS             15046..15855
                     /locus_tag="SCH06_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEG1077945.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(15958..16587)
                     /locus_tag="SCH06_001358"
     CDS             complement(15958..16587)
                     /locus_tag="SCH06_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEG1077946.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            16757..18049
                     /locus_tag="SCH06_001359"
     CDS             16757..18049
                     /locus_tag="SCH06_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1077947.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(18125..18787)
                     /locus_tag="SCH06_001360"
     CDS             complement(18125..18787)
                     /locus_tag="SCH06_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEG1077948.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            19012..19296
                     /gene="groES"
                     /locus_tag="SCH06_001361"
     CDS             19012..19296
                     /gene="groES"
                     /locus_tag="SCH06_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEG1077949.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            19347..20972
                     /gene="groL"
                     /locus_tag="SCH06_001362"
     CDS             19347..20972
                     /gene="groL"
                     /locus_tag="SCH06_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEG1077950.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(21061..22209)
                     /locus_tag="SCH06_001363"
     CDS             complement(21061..22209)
                     /locus_tag="SCH06_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1077951.1"
                     /translation="MLKVWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALEDYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKIIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRRLSMNKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYEDGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLPNRAKELIES
                     VIADNILAGRPTDPDQYIFISTSGTPLALHSFNAILHKVEEELELEKSLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(22311..22793)
                     /locus_tag="SCH06_001364"
     CDS             complement(22311..22793)
                     /locus_tag="SCH06_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HEG1077952.1"
                     /translation="MIGSALNGGSDSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKI
                     GDTVKVGDAEYTLNSVELTDERNQFEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYG
                     PDDKKSETYANENTMGSVAPGKQMDVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV
                     "
BASE COUNT         7802 a         3563 c         4597 g         6877 t
ORIGIN      
        1 tagttttaat gaactttatc aatcctattt tgatgttggt acttgtttca cctgtaagtt
       61 taattttcag taaaaaatac ggtaaaaaag aattggcgtc agtagggatg ttcttctctg
      121 ctattgtata tttactttta tttttgataa agcctagtaa tatgtatgta ttcttagttc
      181 ttacttctgt tggatatatg gggttaggta tttttaatac agtcatttgg gcgaatatta
      241 ctgatgtaat cgatgatcaa gaagtgaaat ctggccaaag agaagatgga actatttatg
      301 cagtatattc ttttgcccga aaaattggac aagctttagc tggcggtgtc ggaggttgga
      361 ctctttctat aatagggtat gattcgttag caaaagtaca aagtggagaa gttttacaaa
      421 agctgtataa ctcttcaacg ttgattccag cagtttgttt ctttgttgta ggattgattt
      481 tatttttcgt atatccatta tctaaagaaa aagtattaga aaattataat ttgctaaatc
      541 aaaaacataa ctaggagaaa aaacatgaac agttggatat tttgtattga ttcagatggt
      601 tgtgtcatgg atacaatgac ttataaacac aatctctttt tcgggccaat tgctgcagag
      661 atttttgatg ttcatcatag ggaaaaattc ctacaggatt ggaataatat taatttatat
      721 tcagagactc gtggaataaa cagattttta ggtttagtta aaacattaga aaaaaatgat
      781 gtaccatcga ttaatcgatt aaagcactgg gtatctgtaa caaaagaatt gtctaatcca
      841 tctttgaaga gggaaataga atactctcag tcagaggatt tattaaaagc tttaaaatgg
      901 tcggaagaag tcaatcgaca gattagtcaa gctaaaggat tagataaacc ctttttaagt
      961 gctagagata ctataaaagc tctgaaaaaa tatgggaaga taattattgt aagctcagct
     1021 aataaggaag ctattcaaga agaatgggaa agacatgaat tattatcctt agttgatgaa
     1081 ctgtgttgtc aagataaagg aaaaaaagaa gacattattc gaagtgtaat tgaaaatggt
     1141 tgtgatttgg ataagatatt aatgattggt gattctcctg gtgatctaga agctgcaaat
     1201 aagaataaag ttttctttta tcctattttg gttaataaag aaaaagaatc atgggaaaac
     1261 ttaagaactg atattttatt taaatgttta tcgggagagt atatagatat tgaacaaaaa
     1321 tatatagata ctttttggaa aaatcttact aataagtaga ggagaaagaa aatgactata
     1381 aaagtagact tacgaaaaaa accatatcat ttagatgaag atgctatttc ttggattgaa
     1441 gagacgattg atgctatgac tttagaagaa aaaataggtc aattatttgt taatatggga
     1501 tctagtcgtg ataaaaatta cttaagtagt atggtcaatc agtaccatat tggagctgta
     1561 cgatataatc caggaactgc tgatgaggta tatgatcaaa actatatcct acaaacagaa
     1621 agcaaaattc ctttattaat tgctgctaat acagaagcag gtggtaacgg agcttgtaca
     1681 gatggtaccg aagttggtgt agaagtaaaa attggtgcaa caaatgatgc gaaatatgct
     1741 tatgaattag ggagagtttc tggaattgaa gcatcggcta ttggatgtaa ctggagtttt
     1801 gctcctattg tagatattaa tagaaattgg agaaatccta tcatttctag tcgatctttt
     1861 ggacaaagcc ctgataaagt tttagaactt agtttagctt atatgaaagg tattcaagag
     1921 agtggaattt tgcctgcagc taaacatttc cctggtgacg gtattgacga acgagatcaa
     1981 catctatctt ttagtattaa tagtttaagt acagaagaat gggataattc ttttggaaaa
     2041 gtatactcag gcttaataga agctggatta ccttcaatta tggcaggtca tatccatatg
     2101 ccagcttatt caaaacattt taatcttgat ctgaaagatg aagatttact tcctgcaact
     2161 ttatcaaaag aattaatcac tgacttactt agaggaaaac tcgggtttaa tggattagta
     2221 gttactgatg ctagtcatat gttaggaatg actggggcaa tgaaacggtc agaattattg
     2281 cccacttcta ttgcggctgg atgtgatcta ttcctatttt ttaatgatcc agatgaagac
     2341 tttaattata tgatggaagg ttattacaaa ggaattattt cagaagagcg tttacgtgat
     2401 gcattaagaa gaattttagg cttaaaggct aaactaggtt tgcataaaaa agaaaagaat
     2461 aaaattttgt taccgaaaca agaagctatg gaaaaaattg gtttaattga aaataaatca
     2521 atttttaaag aggtagctga tcaagcaatt acactagtta aagataaaca agatatttgg
     2581 cctattgtac cagaaaaata taaaaggatt ttactggtag atgtacatgg ggtaaaaggt
     2641 gggtttggtg aagtagttgc tggaaataga cctcaggcca ttgatttatt gaaacagatt
     2701 ttgtcagcaa aaggatttga agttgaaaaa tacatttcac ctgaagaaga attgaaagga
     2761 ttatcgcaag aagaaaaaat taaaaatata gctggaatat atgctgctaa gagaccaatc
     2821 aaagatttaa ctgaaaaata tgacttgatt attaatatag ctaatgttaa cccaggtaca
     2881 gttcaaagaa ttgtttggcc agcaagtaaa ggtactccgg atattccatt ttatattcat
     2941 gaaattccaa caatttttgt atctgtacag tgtccgtttc atttagctga tgtgcctcaa
     3001 gtaaaaactt atatcaatac ttatgatgga aaacaagaaa ctttagaaat attagtggac
     3061 aaactaatgg gcctttctga atttaaggga ataagtccaa tagatgctta ttgtgggtta
     3121 aaggatacat ttatttaata tttaaattat ataggagtga tttacatgtt atatcccatt
     3181 atgacagaga cgaggcaagt aattgattta agcggtcttt ggagatttaa gttagataca
     3241 aatgatgact tacaagaaga acttgcttta gaaccaatgg ttgaaaaaga gagttatcca
     3301 atttcagttc cttcttctta taatgattta tttgaaacag agaacattag aaatcatgtt
     3361 ggatgggtgt ggtatgaaaa agaagtgatt cttcctaaaa aattattaga agaaagatta
     3421 gttcttcgtt ttggatctgc aacacatgaa gcaaaagtat ttttgaatgg aaaattgatt
     3481 aatcaacaca aaggagggtt tacgccattt gaatcagaaa ttaatcagtt tataaaagat
     3541 ggaagtaaca gaattacagt ggctgtaaac aatgttattg acgatagcac tttacctgta
     3601 gggattttga aagaaacgat acaggaagat ggagacataa aaaaagaaaa tttggttaat
     3661 tttgactttt tcaattatgc aggcattaat agacccgtta aattgtatac aactccgaaa
     3721 gactatataa aggatgtcac tattaataca aaaataattg attcagatgc aaatgtagaa
     3781 tttaatatcg atacagaatg gaccggagaa attctaatag caatctatga cgaagaagct
     3841 caacttatag cagaagctaa ggggaaagaa ggagtgattc aacttaagaa cccaacactt
     3901 tgggagcctc taaatgctta cttatatagt atgaaagtta gtttaattaa cgaaaataaa
     3961 gtgattgata cgtacacaga agaatttggc attcgtagta ttcaggtttc gaatgggaag
     4021 tttttgatta ataataaacc tttttacttt aagggatttg ggaagcatga ggacacgtat
     4081 attaatggtc gtggtttgaa tgaagcagta aatatcaaag attttaattt aatgaaatgg
     4141 atcggtgcta attcatttag gacttcacat tatccttatt cagaagaaat tatgcgctta
     4201 gcagatcgag aaggtattgt agttattgat gaagtacctg cagtaggatt acatttgaat
     4261 ttcatggcta ctttattaga tgacaacgta gaaaaacatg atacttggaa agaaatacgg
     4321 acagaaaatg ctcacaaaat ggcgattaag gaattgatag aacgcgacaa gaaccatccg
     4381 agtgtcgtaa tgtggtctat tgcaaatgaa ccagattcgg attctgaagg cgctaaagaa
     4441 tattttgaac ctttagttga attgactaaa gaacttgacc ctcagaagag acctgtaaca
     4501 atcgttactt acttaaagtc aacaccagat atttgtaaag taggagatat tgtcgatgtt
     4561 ttatgtttaa atcgctatta tggttggtat gtttcaggtg gagacctaaa acatgcaaaa
     4621 tatctgttga aaaaagagct agatggatgg atggaaagat gtcccgatac gccaataatg
     4681 tttacagaat atggagcaga tacagtagct ggacttcatg atacagtacc aacaatgttt
     4741 acagaagagt atcaagtggg ttattacgaa gcaaatcacg aagtaataga taaatgtgac
     4801 aattttgttg gtgaacaagt gtggaatttt gcagattttg aaacaagtca agggatttta
     4861 agagtgcaag gaaataagaa aggaatcttt actagagata gaaagcctaa aatgattgct
     4921 cactatctaa agaaacgatg gtcatcaata ccaaatttca gttataaaaa ataatttacc
     4981 ttttataagg aatataaaaa aggagtggct gcttaattgc caactccttt tttttataaa
     5041 aagattttct gtttaaagaa ggatattttt ttctagtttt ttcgaaaaaa aggcgctttc
     5101 tgattgttgt attagtggaa aggggaaaaa aggagcatat ttatcatgca acaaaattac
     5161 aatgagaaat ctatacaaca tcaatttgat gcctactgta aaaaagtatt acgaaacgaa
     5221 actaagtcta ttcgaaaacg aaacattaac ataacagata atgaggaacc attgacgaat
     5281 tcaaatgaag gtaagtactc ccaaactcat tttgatgaac aagatgtcta tttcttattt
     5341 ggaatggaaa tattaatttc agatcaaaag ttatcggcag ccattgatca tttatcggaa
     5401 ataagaagaa aggttatcct actttattat tttgcaggtt ttaatgatac tgaaatcggt
     5461 aaaatcctca atatgagtac aagtggtatc tggtatcaac gaaagaaggc agttgaacaa
     5521 ttaaaaatgg ggtatgactt atggtagaca accccaaaaa acggcagtat ccattagttc
     5581 ctctatccat tatccaatct gctctagaag aagatccaat ttcaatcaag atgatactca
     5641 aacattatca tagttatata gctaagttat gtttgacaaa tggatttaat gaggcggggc
     5701 aatttattac ctatgtagat gagtatatgc taagacagct agaaattaaa ttgatagaag
     5761 cgatcttaaa atttaaaatt aactaactaa aaagtcccct ttccacttat tctgtttaaa
     5821 agaatcttct aatagttaaa ggattagtag attcttttaa acagaaaacc tattgatcat
     5881 tgaaatttaa atacattcta tcagtacgtt aacacttcaa ggagcatatt ttagttgcgc
     5941 catgatttct tactgtaaag aaggagcgat aaacattcta aaataatttt tatagtcaat
     6001 aaaaagcgat gatttgaagt tgggataatg atacttccgt aaggctcgcc gtaaacttgg
     6061 agagaggtga aattcctatg tgcttttgac aaaagcagct gattaagaat tatttccata
     6121 tgttgatttc aacatttttt ctattatttt taagaccaaa ttcagtgagg caaatagcat
     6181 catgtaaatt tagtttttct attgaacgtt ctccactttt tagttttttt atagtactca
     6241 aatttaatcc tgtatgttta gagatctcat ttgcagtatg gttttgtaaa gtttctcgga
     6301 ttattgttat attagcaatt tcattacgca taattatgtt cctttcttat caaaaatatc
     6361 aatgactaca gtgggctttt agtgaaaaaa aggggtacta cagtctcttt tgaaaacaaa
     6421 aaaatacagt atatacgttt tctaaatgct aagcaccaac gtttacactg tatttaaggg
     6481 tttggcaccc aatgggctgt gaggggctcg aacccgcgac ccgatgatta agagtcatct
     6541 gctctaccaa ctgagctaac agcccaaatt aatactttgt tattctaaca cctaaaataa
     6601 aaaagtgcaa tacttattat cagaattgag agtgaatttt atggattttc aagattatga
     6661 aaaaatattt gaaagttatc catcgatatt gaaaattact gatttaacta aaatgttaaa
     6721 tattggaaaa aataaagctt ataatttgct gaaagataga tcaatagaaa atataaaaat
     6781 tggagcaagg tacaaaatac ctaaaaaagc tgtcattgag tatatattga aaatacaaga
     6841 tgaaggtaaa aatcatgcta taataaaata gtcaaaattt ttgccgatat ttcagtttaa
     6901 gaggagagat tgaattgaaa ttaagagcaa acataattga aaaaagagga acattacaag
     6961 tagttgtatc ttataaagac tctaacggaa aaattagaca aaagtggaaa gatacaaaat
     7021 taaaaaagaa aggaaataaa aaacgagcag aaaaaattag agatgaattt ttactagaat
     7081 tggaaagtca attagctatg gaatgtgaat gtgctaatcc aaatttattg ttttatgact
     7141 atttgcttaa ttatttggaa gtatcaaaaa aacaagtagc atttaacaca tatgttgggt
     7201 ataagcatta cgtccataat cgaatttaca agttttttta tcctaaaaaa attaaactaa
     7261 ataggttaaa gccttatcat ttacaagagt tttatcaata tatgttaaat gataactgta
     7321 cagcaaatac ggttattcat tatcacgcat ttatacgcaa agctcttcaa gaggctgtta
     7381 ttacagaatt gataagtaca aatgtagcag ataaagtaag aaagccaaaa aagaaacaat
     7441 ttgtttctca agtttataat caacaagaga tcttgaaatt acttgacatt ttgtcagaag
     7501 aaaaactcta tttggtagtt cttttaacag cattttatgg attgcgaaga agtgaagttt
     7561 taggattaaa atggtctgct attgattttt taaacaaaaa aatcatgata aaccatgtaa
     7621 tcatagaaaa tccagagaat atgtcacagt taataaagaa agatcaaaca aagaactctt
     7681 ccagctatcg tacattacct ttggttgaaa cgattgaacg agcattagta aatcaagcta
     7741 aatggcaaca agataatcgt attcttttag gagatgatta tattttagaa gataatgagt
     7801 acgtatttac tatggaagat ggacggttga tgaagcctca atatgtaacg catcgtttga
     7861 gtaagttgat taagaaaaat ggattgaaaa aaattcgctt tcatgacttg cgtcattcta
     7921 atgcttcaat aatgttagat agtggccaga atatgaaatc cattcaagaa tggctgggac
     7981 atgcatcgta ttcgacaact gctaatttat acacgcattt aaccgcagga gtaaaagatc
     8041 gtgcagcaga agcattagaa aacgcatttg ggtttaaaga ataaaaaaac aaaaaacaat
     8101 atctttgggg tatcgcttct tgtttttaga atttttttgt tggcaatttg ttggcagtat
     8161 gttggcaatg aaaaaattca caaactaaaa acctatttat aaagctttat aaaacttttt
     8221 tcacaaatag agcatttggt taagagtcag ctgctctacc aactgagcta acggcccgta
     8281 caaaaagtac ttaataatag tagcactaag aattttaaaa tgcaagacta catttaaaga
     8341 aaatcagaaa aatctttact tccttatagg aaatcattca tagattattc acatttgctc
     8401 gctattatat aagcatacca acaaacaaag ttcttgcaag agaacaaacc ctaacacttt
     8461 tttcattttt tactcctttc ccgccgtctc cccggcgggt ctcctgttct taacgataaa
     8521 agacaagaag gcttagcctt cttgtttttt gttttcatgg aatcccgcta atcaaatcac
     8581 ctagttaaag caactagatt gaatgtttat cataagtctg atatcatgtt tatgaaatga
     8641 aaaaaggagc ggttatgatg gaaaaaatgc gtcagcaatt aatggagtgg gggaaggaac
     8701 tagaaacatt ccgtctgcct cactgggaag aactccctga cttagaactt tatatggacc
     8761 aagtcagaac gttagttgat cgttatcttt cacctgtgat acaaggagaa aagcatccat
     8821 tgcttacctc ttctatggta aacaattacg ttaaactagg tttgatacca gcaccagtta
     8881 aaaaaagata taacaaagaa cacgtagcat ttttacttgc aatcactacg ttgaaacaag
     8941 tattgactat tcctgaaatc aaagaaggga tattgttcca aggaaaaaca gtaggaattc
     9001 gtgaagccta taatctattt tgcgatgaac aagaagcagc tgtgtggatg gtcagccaat
     9061 tagcacaagg taaatctcat ccgcaaaaat tcgaccaggc aacccctgta gaatatattg
     9121 ctgtaagagc ggcaacttta tcgtttgcaa tgaaacttct tgcggaaaaa acgattgttc
     9181 tagaaaccga atatttaaaa gaggagaaaa caaatgaaaa acaataaaat cgcaatttta
     9241 gtagattcag gtacggatgt tccagaagaa ttgataaaaa aatacgagat gtatatgatc
     9301 ccattgaaaa ttatttataa agatcaggta tatacagata aaattgacat tacccctgaa
     9361 gagatctatc aacgtttgcc agaggaaatc cctggtacat ctttgccgga tggtgagtcg
     9421 atcacagaaa tctttgagca aatcaaaaaa gacggttatg aaaaggtact tgcggtaaca
     9481 atttccagtg gattgagcgg gacatataat gtggttcgtt taattgcaca acagcaagaa
     9541 gaattggaag catatgtact agatacgaaa aatattggta ttggtgcagg tttttctgcg
     9601 atccaagcag caaaatggct ggaagaagga gtagaatggg atcaactgat cagtaatctg
     9661 aatgagttag tcgaaagaac aaaagttttc tttaatgttg cgacattgga atatcttcaa
     9721 aaaggtggac ggatcggttt agttgcttct attgtaggaa ccgctttaaa gcttaaccca
     9781 atcatctcat gtaatgaaga agggatttat tacacagtag gaaaagctag gggacgtaaa
     9841 aaaagtttgg ataaaacggt tgcttacgtc aaagaaaaaa tcggtaatgc aaaggtcttc
     9901 aacttagctg ttgcccatgg ggatgcgaaa gaagaagcaa ttgaaatgga agcgagactt
     9961 aaaagagagt tcccacaagc aaaccaaatc tactttggcc agatttctcc ggcattagta
    10021 gtccacactg gtccgggatt attgggtgtc ggtgtacaag ttttagaagg ataaatcaaa
    10081 aaaaggaaac actgaggtga aaatcagtgt tttccttttt tattgaagtt agaacaaaaa
    10141 ataataaagt attttgcact ttcattttaa ttttctcttt tgttttatag gcaaagatga
    10201 aacaaaagca gaaatacggt ataatgagaa ggtatgacaa taatatataa gaggtggctc
    10261 tttatgaaaa aagttttagt tgtcgatgat gagaagccga tttcggatat cgtcaaattc
    10321 aatttagcca aagaaggcta tgacgtttat actgcatatg atggggaaga agccttggaa
    10381 aaagttgctg aggtagaacc tgatttgatt ttacttgatt tgatgctacc taaaatggac
    10441 ggcttagaag ttgctcgtga ggtacgcaaa acttatgata tgccgatcat tatggtaaca
    10501 gccaaagatt ctgaaattga taaagtccta ggcttagagt taggcgccga tgattacgtg
    10561 accaagccat tttccaaccg agaattagtt gcacgtgtca aagcaaatct tcgtcgcggt
    10621 gccacggctg cgaaggaacc agaagaggca gcacctgcgg aattgacgat tggtgatttg
    10681 acgatccatc cagaagctta catggtgacg aaacgaggag aaacaatcga gttaacacat
    10741 cgtgaattcg aactactctt ttacttggcg aagcaccttg gacaagtgat gacaagagaa
    10801 catttattac aaacggtttg gggttatgat tattttggag atgtacgaac agtggatgta
    10861 actgtacgtc gtttgcgtga aaagatcgaa gataatccaa gccatccaaa ttatttagtg
    10921 acacgtcgtg gtgtcggtta ctatttgcgt aacccagaac aggagtaatt ggatgaaaag
    10981 aaaagtccgc ttttttcgat cagtcaattt taagatcgct attaccttta ttctgatttt
    11041 attgatctcg atcgaaatta ttggtgccta ctttatacgt ggtttagaac gttccacgat
    11101 caatacattt attaaagata tgaatcaaac ggtggaatca ttagcaacaa caatcagccc
    11161 ggaattgaat cgaaaagata atgcagatga tgaagaggta aatgcgaata tcaaaagatt
    11221 tattgaaaac agtgcgacta gcgatatcat cgaaatacgg gtcgttgacg aaaaagggat
    11281 catccgagga acaaccgatg tcaatgaaca aagcgctgtg ggaaagaaaa atgattatgt
    11341 tgatatcaat gatttcacga ctaaacgtta tgttgcttta gataacgacg ataaacgggt
    11401 gaatatcaat gttcaaccga tcctgtcccc gaccggcgat gccgttatcg gggctcttta
    11461 cgtcaaaagt aatatcgaac aaaaatattc ggaaatcaat aacacagcag tcattttctt
    11521 tactgcctca ctaattgcgg catttatttc aatgatcgta tctgttttag ttgctcgttc
    11581 gattacacag ccgatcggtg aaatgagaga acaagccatt cgaatcgcta gaggagacta
    11641 cagtcggaaa gtcaaagtgc atggacaaga tgaacttgga cagctggctg ataccttcaa
    11701 tcagttagct gaacgtattg aagaagctca agatacaatg gaagctgaac gcaatcgttt
    11761 ggatagcgtg ctatcccata tgacagacgg cgtcattgcg acagatcgca ggggtaaagt
    11821 cattacgatc aatgatatgg ctgtttcctt gctagatatc aaaaacgagg aagcaatcgg
    11881 acaatcgatt ttgacacttt tagatatcga agaagaatat acgttgcgga aattattaga
    11941 agatccaaac gaaatggtac ttgaccgttc aaccagtaca ttggaaagtg atcagatgat
    12001 cttgcgagta gacttttcta tgatccgtcg cgaatcaggt tttatcagcg gattagtagc
    12061 tgtcttgcat gatgtgacag aacaagaaaa aacagaacgg gaacgtcgtg aattcgtctc
    12121 taatgtttcc catgaacttc gtacaccgtt gacaagtatg cgtagttata tcgaagcatt
    12181 gagcgaaggt gcgtggaaag acgaggaagt agcaccaaat tttttgaagg taacgctaga
    12241 tgaaacagac cgaatgattc gaatgatcaa tgacctctta aatctatctc gcatggatac
    12301 aggtaatacc cagcttcaat tagaatatgt caatttcaac gagttagtga attttgttct
    12361 tgaccggttt gatatgatgg tgggaaatca ggaaaaaaat tataagatcc gtcgtgaatt
    12421 tacgcaaaga gatctttggg tcgaagtaga tacagataaa atcatccaag tagtcgataa
    12481 tatcatgaat aacgcgatca agtattcacc agatggggga acgattactt gtcgcttatt
    12541 agaaacgcat aataacgtga ttttaagtat caccgatcaa ggattgggga ttcctaaaaa
    12601 agatctgaac cgagtgttcg agcggttcta tcgagtagat aaagcacgtg caagagcaca
    12661 aggtgggaca ggacttggat tagctatttc tagagaagtg attaaggcgc atcgaggcgc
    12721 tatttgggca gagagcaagg aaggaaaagg gtcgactttt tatatctcgc tgccatatga
    12781 accttatgag gaggaatggt gggaatgaga atctctgaaa aagtcgttcg tataggactc
    12841 attttgatgg ttgcgttaag catatacttc tcttatgcaa tctggctgag cccagcagga
    12901 aaaagttcaa tcaacgtaga tgagacaaac actcaaatga tcgagtctca aagcaatcga
    12961 aaaacttccg aagtctttct tccgcttcat gttacatggc accattcggg aatgatccaa
    13021 gaaaccaaca gtgaaaatct cgtgtaccga ttgcaattga tcatcgataa agcaagattt
    13081 ggaaagcttt ctgaagtagt ttcaggagac aaatcacagt ttgaacaggt gaaaaatctg
    13141 aactctggtt ttgagttggc ctataatgcg ccttttttgc taagagaata caaggaagca
    13201 tttgatttag atttagatgt gtcgaacttg gcaaaagaaa gcgaaaatat gtattttact
    13261 agaatacaat tcgatcaagg aaataaaaaa atccgatttt tgaattattc gaaccatctc
    13321 gtatatgaag caaatatttc gttgaattgg acagatatca ataaagaatt aacagcaaaa
    13381 gacacaaaat ggacagaaat gacaacagaa ccatcgacga tcgacacgca atatgctacg
    13441 aaacattcga tcaaactgaa gaagtatagt tatatcctgt cacagcaacc ctatacactt
    13501 tttagaaatg cttttttcca gaaaccagat agcgtgaaaa ataatgatga aagcaatgaa
    13561 ttgatttttt acggtgggaa tgaaacaatg tctatccatt cggaaacgca agtagttgat
    13621 tttcgtggag agctgccaga gaaaaaagaa aatgctagtg tattttctga aagtttcccc
    13681 tatattagca aattaggcag ttctttaggg aacctcagat attttgaccg cagtgacaat
    13741 acgatcgatt atcggatatt cgtggaaggc ttcccggttt ttgggacaga cagcagagga
    13801 cagattggtg tggaagttgg cggtgaaacg aatggttctg tgcaagtgaa tatccaaacc
    13861 agtttgaata cgattcaagt gccgatacct tcagacgaag aagtagaact tgcaagtacg
    13921 aatgaaatca tccagcagtt aaaagctaag ggagcagata gcaacaagat tggttcagtg
    13981 atcgttggct atacatggca aaatgtcaaa gaaacgaatc gtgtcgttga tctcttacct
    14041 gaatggtatg tgaaatataa agataactgg tattcagcta acgaccttct ggaaaaatta
    14101 cctggattgg aggcgaatta attggatttc aaaaaaatcg aatggatatt tttcgtcgct
    14161 tttttagggt tgaatgtgtt tttattcagc agttatcatg acgcggtata ccaagaaaac
    14221 aatgtcattc gctctaatca gactgaatca atccaacaac gtctggctag cgacgatatc
    14281 acttacacgg ggaagatttc gtctgagaac aagcaaggct attatcttag cgcggagcag
    14341 accaatctta gcacttcatt agcgaattat cgcaaggctg gtaaaagcgg cttgctggca
    14401 agtggtgtgt ttttagacgg tgatgttttg acgaaatctt tatccagttc agatgctgaa
    14461 aagaacgtga tcgatccaga taaaattagt agttccttgg aagatttttt atctaacaaa
    14521 gacaatattt tattcggtaa tgattatgtg tacacgaaaa acttttctca tttagaagaa
    14581 gaaccactag aaatccaagc aagccaagag tatgaaggca tcccattcaa tgatgataca
    14641 gcaaaaatcg ttctttcttt agaaaaaaac gataatgatt atagcatcac gaaatacatg
    14701 cagacgcatt tatctgatat cgagcagctg cgcgaaaaga cggaactgta tacggaagag
    14761 gaagcaatca atacattgta catcaataac aaaataccaa gaggatcaaa aattttatgg
    14821 cgtcagctag cttattcctg tattctgaaa gtccgggaaa aaaatgtgta tgttcctgtt
    14881 tggcatgtag cgatcgaaac aagcgataaa gtggtccaaa ttgagagcgt caacgctttc
    14941 agcaatacga tcgtgacaaa caatactgta ccaaaagtgg aagatcaata aaaaagcgag
    15001 tataatgaaa aaagtttaca aagtaagaag ggaagtagga gtcaaatggc tgaagaaaaa
    15061 ccagctttta aaatcagtat cctagcaagt ggaagttcgg gtaattcact ttatatcgaa
    15121 agtgaaaaaa aacggctttt ggtcgatgca ggacttagcg gtaaaaaaat cacttccttg
    15181 atggctcaaa ttgatcggac accggaccaa ttagatggaa tacttgtgac gcatgaacat
    15241 cgagatcata tacatggcgt gggtgtcttg gctcgtaagt atcatttgga tgtttttgcc
    15301 aatcagcaga cttgggaagc gatggaacca ctgattggaa atgtaccagt ggaacaaaaa
    15361 catctatttg agatggggaa agtcagaaca ttcggcgata tcgatattga gagtttcggc
    15421 gtctcccatg acgcagcggc tccgcaattt tatcgtttcc ataaagaaaa tcggtcattc
    15481 gtcatgttga cggacaccgg atattgcagt gattatatgc gaggtgtcat tgaaaatgcc
    15541 gatggttatt tgatggaaag taatcatgat cttgagatgt tacgcatggg accttatccg
    15601 tggaatttaa aacagcgtat tttaggagat agaggacatc tttccaacga agacggtgca
    15661 cttgtcatga ctgatgtgat cggtaatcgg accaaacgaa tctatcttgg ccatcttagc
    15721 aaggaaaaca atatgaaaga acttgctcat ttaacaatgg aaaatgtttt gaaagaaaaa
    15781 gattttggcg ttggacatga ttttgaaatc tatgatacag atccagatga agcaactgag
    15841 ctattttcga tttaaacagt tcaatcaata aaaatataaa aagcagaaga taaaatcaat
    15901 cagggttggt tttatcttct atttttattt ttttagcata ttaaaaaaat aaccgtatta
    15961 tcgactgact acactgatgt gctgcttttc atgtttctca tccagtatct catctactaa
    16021 tgcaatcgcg taatctgcca tgctgatcgt actgtcgcta gcagcgtttc tttgtaaata
    16081 atcatcactt aacaaataag tacctgtacg tttgccatgt ggatcaaata aagaagctgg
    16141 actgatataa gtccaatgta gatttttaga ttgtttcaat tttaacaatc cttcgtacat
    16201 attgaaagct gttggataga agggtgcatt tttaggtact tggtcaatca tacgagtcgt
    16261 cttttctgta tctaagaata acgaagaggc acccccaacg acaattaagc gtgtatcggt
    16321 tccttcaagc atctcaatca aatgggacaa agaagtttga tgcatttctt cttttccttt
    16381 gggagcgttg aaagcatcaa cgacaacatc aaaagatgca agatcagtag ttgtcaactc
    16441 aaataaatcc ttttgtataa acggaacatc tgatggcaat ttttctggat gacgcacgat
    16501 tgccgtcacg tctaaatctc tggacaatgc ttcgtctaaa ataaatgaac ctgcatggcc
    16561 agtagctcca atgagtgcaa ttttcataaa aaacctcctt ttttattcct gtccattgta
    16621 agcagttgct gaatattcgt caaagaatcc gatttttgaa aagctcagtg cgcattcctt
    16681 tcatggttcg tgatcattgg gtatagttaa attaagaaaa ctgattgata aaaatagaag
    16741 ttgaaggaga taagaaatga aagagtggtt agatcgtgcc tttttaccaa tgataacatc
    16801 tgttgtgaat cttagaccct taactgcttt gcgtaatgga atgacttaca cgatcccaat
    16861 aattattgtt ggctcgctgt ttttcttatt tgctcatttt cctgtggatt acatcgctca
    16921 gtggatagac aaaacaggat tttctatgta ttttacacaa gtataccagg ctacatttga
    16981 tgtgatagcc ttttggatcg tttttgccat tgcatacgct tatgcaaaag aagaagacat
    17041 cgatcgctta ccagtcggca taacagcctt gtctgcttat ctactgctta ttcagccact
    17101 aaatactcag atagatactg tctggacagg tgctgaaggg atactaggag cagttacaac
    17161 tgggctcatc atcggatggg gctatgcacg tttagtaaga cttgcgaaag ggtggaagca
    17221 aagagagaag atacctgaaa atgtttggca gtcttttact tcattgattc caatcattgt
    17281 tatagtcact tttacgctta tcggttcagc ggtttttcaa catttgttca gaatgactgt
    17341 tgttcaagga gtatggacat atgtccagct tcccattcaa tcgttcatag acacgttgtt
    17401 tggtgtgctt ttattaggtt tttttgttcc gtttttatgg ttatttggtc ttcatggatc
    17461 tgcgatggtc aatgggttgg ttagtcccgt cttgcaagcg aattcattag caaatgcaga
    17521 aatcttagcc tcaggacaag agttgacggt ggcaaatggc ggacatatcg ttactcagca
    17581 atttctcgat cagttcatga cggttacggg tgctggattg acgttagggg ctgtattttt
    17641 tatgacggtt tttgcgaaat cgaagaaata cagagaatta ggaaatcttg ctcttttacc
    17701 agcctttttc aacatcaatg aatcaattat tttttccaca ccgatcgtga tgaacccgat
    17761 gatggctgtt ccttttattt tcgcaccggt cgtttcagga ttgattacct attccgcttt
    17821 atattttgga ttcgttcctt tatttacagc agtccaagtc ccttggacaa caccgccgat
    17881 cctctcgggt ttcttagtag gcggagtgcc tgcagcgatt ttacaaggta tcgtgttgtc
    17941 aattagtttt ttcatttatt tcccattttt gaaaaaaata gattctgcaa actgcaaaaa
    18001 ggaaagacag acaaaaaatg atggagcagc agaaaagatg aacgactaaa aaacaaaaat
    18061 actcctgtcg ctttagattg ggaaaatcac caatctagga tgacaggagt atttatagtc
    18121 atgtttatac tagccctttt tggacagcta attgaacaag aacaactaat gtgttcattc
    18181 ctacgtgtgt gatcatcgat gtccagatcc gaccagttgc tttgtactct aggctgaaga
    18241 agaaacctag gaaaaagtag attagcagat gaccatcatt atgagcaaac gcaaacagca
    18301 aagagctgat cactgctccg acccaaaaat ttgaatatcg actgatgatc cccagtatac
    18361 tgcggcggaa tacgaactct tccatgatgg gtccagcaac agttgtcgcc aaaataaaag
    18421 cgggtgcttc catgatcatc tggatgatat tttgtgtatt ctcggaaggg gttgctttgc
    18481 caaacaatac agattctaac atgacagcga tgctttgcag aatcaatgcg acaaagattc
    18541 caaccaatcc ataaataaca atctttggag cagaagcttt ttttaccgct gattcgatcg
    18601 ctaagggttc acgttgctta aaataaaaaa tagctaggac aacggcgcct agtatataca
    18661 tgactgcagt tgctgtgatc aattcagacg tagattttac aagtcctatc gaagctagga
    18721 tcaagggtga gataaaaatt agaccatagc aaaaaatgct gaggaagcta tattttttta
    18781 aagacatgta attcctcctt ttaagggata acaagcatgc aaggcaagct tatatcgatt
    18841 gatttcaatt atatcataat ttcaataagc agctgtcaga ataaaatttc ttttctttga
    18901 tttaaaagct tgcaaaaaag agggagaatg agtattatta aaaatgtagg ttagcactcg
    18961 aaggttaaga gtgctaacag attaaaaaaa gagttatcgg agggatttat cgtgttaaaa
    19021 ccattaggtg atcgcgtcat tatcgaagtc gcaaaagaag aagaaaaaac tgtcggagga
    19081 atcgttttag cttctgctgc taaagagaaa ccccaaactg ggacagttgt tgcagtcggt
    19141 gaaggccgtt tgttagaaaa cggtgaaaaa gttcctgccg ctgtaaaagc aggcgaccaa
    19201 gttatgttcg aaaaatacgc cggtacagaa gtaaaatacg aaggaaaaga atatctgatc
    19261 gtcgcaggaa aagatatcat ggcgattgtt gagtaaattt ggaagataaa aaaataatca
    19321 aaaataatca atgaggtgaa tcaatcatgg caaaagaatt gaaatttgca gaagacgcac
    19381 gcgcagctat gttacgcggg gtagataaat tagcagatac agtgaaagta acattaggac
    19441 ctaaaggccg aaatgtcgta ctagaaaaat cttacggctc tccattgatc acaaatgatg
    19501 gtgtgacgat cgcaaaagaa atcgaattag aagatcattt tgaaaacatg ggtgcaaaac
    19561 ttgtatcaga agtagcatca aaaacaaatg atattgcagg agacggtaca acgacagcaa
    19621 ctgttctgac acaagcaatc gttcgcgaag gtttaaaaaa cgtaactgca ggtgctaatc
    19681 ctctaggcat tcgtcgcggg atcgaattgg caacaaaagc agcagtcgaa gaattgcata
    19741 atatctcaac tgttgttgat tcaaaagaag ccattgcaca agtagcagct gtttcttcgg
    19801 gttctgataa agttggacat ttgattgctg atgcaatgga aaaagttgga aacgacggtg
    19861 tcatcacaat cgaagaatca aaagggatcg aaacagaact agatgttgta gaaggtatgc
    19921 agtttgatcg tggttactta tcacaatata tggtaacaga taacgacaaa atggaagctg
    19981 ttctagaaaa cccatatatc ttgatcacag acaaaaaaat ctctaacatc caagatattc
    20041 tgccattgtt agaacaaatc ttgcaacaat cacgtccatt gttgattatt gctgacgatg
    20101 tagatggtga agcattgcca actcttgtat tgaacaaaat ccgtggaaca ttcaacgtag
    20161 tagctgtaaa agctcctggt ttcggcgatc gtcgtaaagc aatgcttgaa gatatcgcta
    20221 ttttgacagg tggtacagta attactgacg atctaggttt agaattgaaa gatgcaacaa
    20281 tcgaaaactt aggaaatgct tctaaagttg ttgtagataa agacaataca acgatcgtag
    20341 aaggttctgg agaaaaagaa gcaatcgaag ctcgtgtgca attgatcaaa aaccaaattg
    20401 ctgaaacaac ttctgatttt gaccgcgaaa aattacaaga acgcttagct aaattagcag
    20461 gtggtgtagc tgttgttaaa gttggtgcag ctactgaaac agaattgaaa gaattaaaat
    20521 tacgcattga agatgcattg aatgctacac gtgccgcagt agaagaagga atggtctcag
    20581 gtggtggtac agctctagtg aacgttatca gcaaagtttc tgctgtagaa gcagaaggag
    20641 acgtggcaac aggtatcaag atcgttgttc gtgctttaga agaaccaatt cgtcaaatcg
    20701 ctgaaaacgc tggttatgaa ggatcagtga ttgttgataa attgaagaac gtggaactag
    20761 gcactggttt caatgctgct actggagaat gggtaaacat ggttgaagca ggtatcgtag
    20821 acccaactaa agtaacacgt tctgccttgc aaaatgccgc ttccgtttct gccttgttat
    20881 taacgacaga agcagtcgtt gcagataaac cagaaccagc agcgccagca gctcctgcaa
    20941 tggatccatc aatgatgggc ggtatgatgt agtaattaag aaagaaccct attttaacag
    21001 ggttctttct tctttttttg ttttatttta agcaaaaggg gcaaagaagg ggcaaaaata
    21061 tcaaaggcta tttagtttat caattacttg ttgtttggct ctttttgtta catggttata
    21121 aatagacaga gttgtgtttg catcagaatg ccctacacgc tccataatgg ctttaagagg
    21181 tacgcctaat tcagataata gtgaaacgtg gctatgtctg aatatatgtg aggatagact
    21241 tttttctaat tccaactctt cctctacttt atggagtata gcgttaaatg agtgcagcgc
    21301 aagcggagtg ccacttgtag atataaatat atattgatcg ggatctgtgg gtctacctgc
    21361 aagaatattg tcagctatca cactttcaat caattctttt gcacgattgg gtaattgcac
    21421 ttcacgttgc gaataagtat tttttggagt tgtttttata gcattatcca ttttcacaga
    21481 tgtgtaatct aaggtcccat taatggaaat tttcccatcc tcatagtcct tcatttgcaa
    21541 agctagcaat tccccatatc tcaaaccagt taaatataga aactcagcta ttatgccgtg
    21601 tagttttctg cgaggattgg agtatagctg tttcagtatt tgatcaattt cttctttctc
    21661 cagatatttt ttattcatag aaagccttct tttttcttct tccacttttt taggatggat
    21721 tttaactgct agcgcagggt ttctttgaat gtattttcta tcgattgcat agtttagcat
    21781 aacagataga gttgtttttg tttgttttgt gtagttcagt gagaggtcac caaacgtata
    21841 catatcttca attatcttat taatgagtgt ctcatcaatg tttctaacga tcgtatcatc
    21901 gcttatgtgc ttagaaacat gtttcatcat cattggaacc ttcaaatagc tagtacgttt
    21961 aacatgctgc ttataatatt cataccattc tttatacagc tcaccaaaag tgatatctga
    22021 tttattgtaa tcttcgagtg cttctttaat ttttttatct agaattttct gagctttttt
    22081 ccacgcttgt ggtgaattac ttgtaagtgt tgtagatttt tttcgtgttt tttctgtata
    22141 aggatctaca tatctttcaa taaacttgaa ttggccatct ttggtctgtt caacccacac
    22201 ttttaacatc tcctatcatt tgctataata ggcataacaa atagacctat ataggtttgt
    22261 tttctaaaag cacgctctta ctctggacgg tggggcgtgt tttttattta ttatacagtt
    22321 gctttaaaaa tagctgcttt ttcaaatgat actaaaggag agaagtggat ttctatttct
    22381 cccttttggt ttaacgtgaa atgagcagtt acatccattt gttttcctgg agcaacagat
    22441 cccattgtat tttcgttggc atatgtctct gattttttgt catctggtcc atatacttcc
    22501 acatctgtac ctacagggat atctgaatcg ccatcatttt ttacggtata agtaattttt
    22561 actacttgtg caggttggtt ttcttcaaat tgatttcttt catcagttag ttctacacta
    22621 tttagtgtat attcagcatc accaactttt acagtgtcac caatcttata gaaggtatcg
    22681 cttttttctt ctttagaaga tgaagcagag gttgaagatt tagttacttt ttcgccacca
    22741 ttatcacttg ctttattact atctgatcca ccatttaaag cagaaccaat aattataatt
    22801 aaaattactg ctaataccca aaaccatact tttttgtaa
//
LOCUS       DARBDN010000035        22829 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000035 DARBDN010000000
VERSION     DARBDN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.035"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..310
                     /locus_tag="SCH06_001365"
     CDS             <1..310
                     /locus_tag="SCH06_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1077953.1"
                     /translation="QIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNL
                     IEGFNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF
                     "
     gene            362..532
                     /locus_tag="SCH06_001366"
                     /pseudo
     CDS             362..532
                     /locus_tag="SCH06_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(705..1178)
                     /locus_tag="SCH06_001367"
     CDS             complement(705..1178)
                     /locus_tag="SCH06_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1077954.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1190..1726
                     /locus_tag="SCH06_001368"
     CDS             1190..1726
                     /locus_tag="SCH06_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1077955.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1766..2137
                     /locus_tag="SCH06_001369"
     CDS             1766..2137
                     /locus_tag="SCH06_001369"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1077956.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2421..3692
                     /locus_tag="SCH06_001370"
     CDS             2421..3692
                     /locus_tag="SCH06_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEG1077957.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            3937..4962
                     /locus_tag="SCH06_001371"
     CDS             3937..4962
                     /locus_tag="SCH06_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077958.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5256..6365
                     /locus_tag="SCH06_001372"
     CDS             5256..6365
                     /locus_tag="SCH06_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEG1077959.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6448..7344
                     /locus_tag="SCH06_001373"
                     /pseudo
     CDS             6448..7344
                     /locus_tag="SCH06_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7360..8184
                     /locus_tag="SCH06_001374"
     CDS             7360..8184
                     /locus_tag="SCH06_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1077960.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8216..9526
                     /locus_tag="SCH06_001375"
     CDS             8216..9526
                     /locus_tag="SCH06_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HEG1077961.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9674..10933
                     /locus_tag="SCH06_001376"
     CDS             9674..10933
                     /locus_tag="SCH06_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEG1077962.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            10943..11815
                     /locus_tag="SCH06_001377"
     CDS             10943..11815
                     /locus_tag="SCH06_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1077963.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11827..12657
                     /locus_tag="SCH06_001378"
     CDS             11827..12657
                     /locus_tag="SCH06_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1077964.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12697..14880
                     /locus_tag="SCH06_001379"
     CDS             12697..14880
                     /locus_tag="SCH06_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEG1077965.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            14941..16161
                     /locus_tag="SCH06_001380"
     CDS             14941..16161
                     /locus_tag="SCH06_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HEG1077966.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16158..17618
                     /gene="gtfA"
                     /locus_tag="SCH06_001381"
     CDS             16158..17618
                     /gene="gtfA"
                     /locus_tag="SCH06_001381"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEG1077967.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17695..18801
                     /locus_tag="SCH06_001382"
                     /pseudo
     CDS             17695..18801
                     /locus_tag="SCH06_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19123..19332
                     /locus_tag="SCH06_001383"
     CDS             19123..19332
                     /locus_tag="SCH06_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEG1077968.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19325..19474
                     /locus_tag="SCH06_001384"
     CDS             19325..19474
                     /locus_tag="SCH06_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEG1077969.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19628..20293
                     /locus_tag="SCH06_001385"
     CDS             19628..20293
                     /locus_tag="SCH06_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1077970.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20577..21662)
                     /gene="xerS"
                     /locus_tag="SCH06_001386"
     CDS             complement(20577..21662)
                     /gene="xerS"
                     /locus_tag="SCH06_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEG1077971.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            21996..22229
                     /locus_tag="SCH06_001387"
     CDS             21996..22229
                     /locus_tag="SCH06_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HEG1077972.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22226..22633
                     /locus_tag="SCH06_001388"
     CDS             22226..22633
                     /locus_tag="SCH06_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEG1077973.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
BASE COUNT         7790 a         3446 c         4344 g         7249 t
ORIGIN      
        1 tcaaataagg tttatgatag ataaatggaa aaagcagtat ccacgagtgg ttaaattgct
       61 catgaatcct gctatattaa ccttttataa tttccctccg tcaatcagaa gaactattta
      121 ttcaactaat ttgattgaag gttttaacaa acaattaaag aaatatacca aaagaaaaga
      181 gcaatttcct aatgaagaat ctctggagag atttctagta tctcaattca acaactataa
      241 tcaaaagttt ctatgccgag ttcataaagg ttttaaagaa atacatgata cattagaatc
      301 aatgttttaa cttgatcaac agaatgggct tttccattta cacaaaatta ttgacgctcc
      361 cacacataca ttaagaaaaa cttttgggta tcactactac aagaaaacta gagacattgc
      421 taccttaatg tttattttta atcatagctc gcaagcaatt acaaaaaggt acattggtat
      481 aactgaagat gaaataggag catcacttcg tggatttaaa ctaggtgtat aatttaaaaa
      541 tttttataaa cagtaaagac aaagattaaa agctattttt atctagaacg attttatttc
      601 ataaagttcg cggaataaaa gctggggtta ctggtacttg gtataggttc gtgttatata
      661 aactaagtaa ttaaataaca tttttaggtt ggaaaaggat gaaattaaaa aaagagaatc
      721 aatacggtct caaaaacgca aacgctgcgg aataagaaaa atactgataa ctcaacgttt
      781 agcagactat ctaataggga tagtctgctt ttttcgtttt tgaccatact tttgaccttc
      841 tgcaaacttc cttgcttttc ctctgtagaa ctcatgaaat ctgcaaaacg aattgccgtt
      901 tcctctgtct gctttttcgc gatatgggtg tatatatcat ccatagtggt tttaatatct
      961 gtatgtccaa gtcgaacata cacttctttg acagacgcac cagattcaaa gagcagacta
     1021 caatgggtat gacgaaaacc atgaagtgtg atatgtttta agttattctc tttaatgatg
     1081 attttcaaat tgtgatttac atagtctaaa taaaggggct tattttcttc tgatgaaaac
     1141 aaaagttgtt caccatcttt tataggtttg attctcattt ttagatatta tgcccgcacg
     1201 tattcatcac atttctattg tgaatcgctt tattcgaccg acatttgact tttatcataa
     1261 tatactcggt ttaaaattac taatgaaaac aattaatcaa gacgatcata ccatgtatca
     1321 cctgtttttt tcagataatc accaccgtgt gggaactgaa ctgacttttt ttgaagtaca
     1381 agaagggaac aaccagtttt ttggaaccaa tacgattgaa cgaacgatac taaaagttcc
     1441 ttccgaagca tcattgcatt tttgggaaat atattttgaa acacaaggcg tttgccatta
     1501 tggaatcgaa tcattttctg gacgacctat cttacgtttt gaagggccag atgcaacacg
     1561 attagcttta gttcccttac gcgaatttga agatattgat gattatttcc cgtatgtcac
     1621 agaccagatc cctacagagc atgccatttt aggaattgat gccattcaac tacgcgtaca
     1681 atattccgat gcgactgaac gagagttatt gtcggtaggc tggtagcaca aagaatacgt
     1741 cagtttcttt tcgggtcatc aacgagtgac aatcttagaa aatcaagaca ctcagttcta
     1801 tcaagaagtt cagattattc aagatcgtga gaatccagtt gccattgaag ggattggtag
     1861 cgtccatcat gttgcgtttg gcgtagaaaa taaatctgat ttacaacgca tcgacaaaca
     1921 attacaagag cgcaatttta taaattcagg aataaaagat cgtgaatttt ttgtatcact
     1981 ttattatcgt gacccaaatc aattattgat tgaaattgct acaggggaag gaaacctaga
     2041 tgcaaaagcg tatgaaaatc aaagtccacg ctttgaagaa attcctttat ttttaccgca
     2101 gtacttaaat ttcattcgtg aacaagtgga gcaataatta gctaatcaaa tccatgacga
     2161 agagtaagag gttgactcat aagtcaaaaa ataaagaaaa acgcatcaaa tccattctaa
     2221 agaatgttga tttgatgcgg ttcctatttt tataaactat cattttcgac taataaaact
     2281 acttatgagt cagcctctct ttttttcttg atttttatac ctctttctag gtaaactaaa
     2341 catctgccaa aaataccgtg tctcattgaa acattctcaa ctatttcaaa ataaagggga
     2401 gtaccaaatg aacgagtata ttgaaattat ccacgcaaga gaaacaactt aaaaatgtca
     2461 gtctcaaaat tcccaaaaat aaaattagta tttttaccag cgtatctggt tcaggaaaat
     2521 catcgattgt ttttgatact attacccaag aagctggtcg tcaactgaat gacacctatg
     2581 atagttttac ccgtttattt ttacctaaat acagtcgtcc agaggttgat gagattgata
     2641 atctttctac ggcgattgtg gtcaatcaaa agaagattgg tggcagtgcg cgctcaacgt
     2701 tagggacgat tactaacatc aatgcgttat ttcgtgtgtt gttttcatgt tttgcaacac
     2761 ctagtttagg atatgcaaat gcttattcat ttaatgatcc tagtggaatg tgttctgtct
     2821 gtcagggaat cggtaagacg attgcatttt taataggatt gctttatttt tcggctattg
     2881 ataatgctga ttttgtattt tctgatccat ttaccgcaga agttttgtct ggaattgagg
     2941 aacaggcaaa gaatcatggt tattttgtat tggtgcataa tgttaattca gcagaagatg
     3001 ttaaaactat tcagagaaat tggcgttttg aggggttcat tgttgttggt gtacgtgtaa
     3061 aagaattttt ggaattaaat aacgtttttg atggtcctgt tgtttatatt gatacgcatc
     3121 tttcaaaaga gacattaaga gaacttgaac aacaaatgaa tcgtttattt gtaaatacaa
     3181 atgattacca agctagtaca ttggcagtgg aacatttgat tcattatggt catgagaaaa
     3241 tagcgtttct ttcttttgac tacattgtag gtgaaccaag tgttattcaa gaacgacatc
     3301 aagcttatat cgatacatta aagaaatatc atttaacctt taaatcgcat tggatatata
     3361 acaactctga atttgagcga atttatcaag aattagctga atttactgca attgttgtta
     3421 ctggagatta tttagcggct aaattagtaa aatttttaaa aaataagaat aaacgagtga
     3481 tggaacaatt atcgattatt ggatttgatg atattacttt tgcagaatta atggatcctg
     3541 cgttgacaac aatacgacta aatccaggta acaagggggc gattgctttt caccaactga
     3601 ttggactggc caaacaagaa gaaataaaaa atcaagtact actattagag ggagaattga
     3661 tttctcgaga ctctgttcac aaaatcaaat aaaaaagctc tgtgaaataa gtatagttaa
     3721 caataaaata tccgaacgat agagagaatg aactgtgatc tagcagttcc tcgtcgcaaa
     3781 ttcactagaa ttagcattat ttactctaaa ttgttcggat attttttctt gtttttaatt
     3841 atgattacag tgcctatttt taacgaaatt tgcttatttt caaaatgtat gattatatgt
     3901 tagtaaacac tttcaaatat gaaaagagga gctattatgg taggaattag ggatgttgca
     3961 aaacgggcgg gtgtgtccat tgcaacagta tcgcgcgtgc taaatgagga tccgacactt
     4021 tcagtaaccg atgaaaccaa acgaaagatt gcagaatcgg ttaattttta tcattatgtc
     4081 aaaaaaagtc ccgttgcaaa aaatttaaca aatattgcat taataacgac agtttctgaa
     4141 gtagatgagt tggaagatcc ctattttcga acgattcgca gagggattca agtcgaagca
     4201 gaacaaagca aagtcaattt gaagaaaatt attcgtttgt cagaaacacc gttggagcaa
     4261 gacgatttgc taaaatgtca aggtgtgttg attattgggc aggtgctatc ttctgtgatt
     4321 gaagaagtat cagcaattaa ttcgaatgtc gtagtgattg atgaccctag tattgaagct
     4381 gaagtagatg cagtttatac tgatttaaca aaagcaacga atcagcattt agatcgattg
     4441 tataaaaaag gacaccgaaa cattgcgttt atcggaggag gacgtgttcg tttagatagc
     4501 caaggaaata aacacgtgtc agatgatgat tatcgaaaaa tagcctatga gacgtggatg
     4561 aaacaaaaag gattagaaaa atatagtcaa atttatttag aaggctggac cacacttgac
     4621 ggaatgcagg cagcagattt acttttgaaa aaacatgcta aagataagtt gccgactgct
     4681 atcatggtag gaaatgatcc tattgctgtg ggggtttatc gttcacttca aaaaaatggt
     4741 ctacatattc cagaagatat ttcgattgtg agttttgata atattgaagt tgctgaattt
     4801 ttaacacctg cattaaatac ggtgaatgtg aatacagaag aaattggaaa actagcagtt
     4861 cgcatggtta atgaacgaat aaaagaagtt agaaatgttt cgatcaaagt gattgtttct
     4921 aataatatta ttgttagaga aagtgaaaaa aatatcgatt aaaaaagtaa acatccaaaa
     4981 aagggtgttt acttttttgt ttactaatat ttttagtaaa aaatctcgac aaaacattaa
     5041 gtaaacagtt atggtgttgt taacaaaaag aaaacgcatt caaaacagga ggaattaaga
     5101 tgaaacattt caaaaaaata gctttaacag ggatagctgt tttaactggg acattactcg
     5161 cagcatgtgg tgggggagat agtaattcta aagacgggca agtaacttta agctatgcga
     5221 gttgagatac tgaccaagct ccaggactaa gaaaaatgtt agatgaattt gaaaaacaaa
     5281 atcctgatat caaagtagaa atggagacaa cgccttggga tcaatattgg gttaaattag
     5341 aagctgcaac aacgggaggt aatatgccag atgtagtaac catgcactct agcgaatcct
     5401 ataaatatat gtcacagaat gctttgatgg gacttgatga tgttatcaaa gaaaatgata
     5461 ttgacatggg aaactttact gaaggaattg ctgatttcta tacgcttgaa gacgaactat
     5521 acgcaatccc taaagatgct tctgtagtgg ggctatggta caacaaagaa ttatttgata
     5581 atgcaggtgt cgattatcca gatgaaacat ggacatggga aacactcaga caagctgcaa
     5641 ttgatttaac agatgaatca aaaggcatct atggttttgc atcacatatt ggaacagaga
     5701 ctggctactg gccatttatt tatcaaaatg ggggagaagt atttgccgat gacaatacaa
     5761 aatcaggttt gaatacccca gaagcacaag aagctttagc tttttatcga gatattgcac
     5821 ttgttgatca tgcttcacca acaattacag aattacaaga tcctgataag ttaagtcgtt
     5881 ttcaatcagg tagattagca atgatgattg aaggaaactg gtttgcaccg ggatttttga
     5941 aaaatgacta tctagttgaa aatgttgctt ctgccgtgtt acctaaggga aaagttaatg
     6001 caacaattac aaatggactt ggttgggctg ccagtgcgag tacaaaatac ccagaagaag
     6061 tgaaaaaact aatggcattt ttagctagtg aggacgccaa taaaatccaa gcggaaacgg
     6121 gggcatcaat cccagcacta aaaggctttg aagacgagtg ggctgcttct tcagatacaa
     6181 ttgatttgag tgcttttgga aaaatgttgg agtatggagt ccctcgtcca tacaataaag
     6241 atggattacg agctgaacaa gcagaagttc aaattattaa ccgtattctg tctggtgaag
     6301 taactgttga agatggaacc gctcaaattg aaaaagaagt caatgcgata ttgagcggaa
     6361 attaaattag ttaattatac aatatacagg cgaaaggatt ctatttcgtc tgtatattaa
     6421 tggatgaata ccaaaaaggg ggatattatg aaaaatcgaa tttttggaaa atatcgtaaa
     6481 gatcaagtga tatggggcta tatttttatt tttccaacgg cattaggatt aattttatta
     6541 aatatatggc cagcaattca aacagcaatt ttaagttttc aaaaaacggt agggttcggt
     6601 gatactgaat gggtcggatt aagaaattac caaaaaatgt ttgcagacgg tgaagttttt
     6661 cagtctttat taaacacatt aatttatgca gtggtttcga tacctagtat tgttgtatta
     6721 tccttgttgg tggcagtttt aatgaataga aaagttaaag gattgtcgat ttatcggaca
     6781 atttattttc taccagtcgt tgctgcacca tccgcagtcg caatgatttg gcgctggatg
     6841 ttcaataatg attatggact gattaataac atgttggcta aaataggtct cgatggacca
     6901 gcatggttaa cggatccatc gattgcgatt tattctatta tcattgtagg agtttggagt
     6961 gctattggtt ataacatggt gttattacta gccggcttat aagaaattcc taaagattat
     7021 tatgaagcag cggaaattga tggtgctagt ccaatccagc agtttttcaa cattacgtta
     7081 ccattagtta caccaacatt attttttgta gttgtaacaa cagttatcaa tgctttccaa
     7141 gtatttgatg ttatttttat gatgattact cctaatagta ccgccatgtt taaatcacaa
     7201 tcattagcct atttattcta taaacattca tttattttaa atgacaaggg atatggttcg
     7261 gcaatcgtta tgttcctttt agtgattata ttaattatta ctgcaattca aatgaagttg
     7321 cagaaaaagt gggtaaacta ttaaggaggc tatcaaatta tgaaaaataa atttttttca
     7381 aatgcgccaa tccatatcat gcttatttta ggtggtattg caatggcatt accttttatt
     7441 tggatgattt taacttcagg gaaaacgttg gttgaatcta cccaaattcc acctacaatt
     7501 ttccctgaga aatttcagct aagtaactat caacaagtac ttgatttatt accattcatg
     7561 gctttttata tcaatacatt tttaatggtt gttggacgag tgattggctc ggttttattt
     7621 tcagcaatgg ctgcatatgc ttgtgcgcgt ctaagttttc cagggaaaaa tatccttttc
     7681 agcttagtac ttattcaaat gatgattccc ggttccattt ttattactcc acagtattta
     7741 ttagcacaaa aattgggtat tttaaataca attccagcat taatattacc aggggtagtt
     7801 agtgcgtttg gtacgttttt attaagacaa tttttcttag gtttacctga tgaattggag
     7861 gaagcggcct atttagaagg tgccaatatt tggacgatct ttttcaaaat tatgttgccg
     7921 cttgctaaat caggattggt tgcacttgga atattcacag cgttgtttgc atttaaagat
     7981 ttaatgtggc cattgattgt caatacttca attgataaga tgcctttagc tccgggatta
     8041 gcaaacttac aaggacaata tgccacgaac ttcccacaat taatggcagg ttcgttatta
     8101 gcaatttggc caatagttgt gatattcatc gttttccaaa gaaaattcat tgaaggaatt
     8161 gctacaacag gtagtaaatt ataaaactat taattagtga ttggagagta agtacatgac
     8221 aaaaattaca tttattggtg caggaagtac tatttttgca aaaaacgtat taggcgatgc
     8281 gatgttaact ccaagtctac aagatgcaca tattgcattg tacgatattg atgaaaaacg
     8341 actaaaagaa tcaaatttaa tgcttaaaaa tattaataaa aattcgaatg aaaatcgtgc
     8401 tgatattgtt tcttattatg atcgcaaaga agcgttaaga gaggctgatt ttgttatcaa
     8461 tgctattcaa gtgggtggtt ataaaccttc aacagtgatt gattttgata ttcctaaaaa
     8521 atatgggttg cgacaaacta ttggtgacac catggggatt ggtgggattt ttagaaccct
     8581 acggacacta ccagtaatgt tagactttgc taaagaaatg gaagaagttt gtccaaatgc
     8641 ttggttattg aactatacaa atccgatggc gatgttaacc atgggtgttt taaaagcgac
     8701 gagtattaag actgttggtt tatgtcatag cgttcaagta tgcgtaccag aattgtttga
     8761 gcatttagga atagccgatc aatatgactt aaatgacttt caatggaaaa ttgcaggcat
     8821 taatcatatg gcattcttgt tggaaattac aaaaaatggg gaagatttct atccaacaat
     8881 tcgtcagtta gctgcagaaa aaccaaatcc acatccagat tctgtacgtt ttgaattgtt
     8941 gaaacgtttt ggttactata ttacagaatc aagtgaacac aatgcagaat accatccata
     9001 ctttattaaa tcaaaatacc cagaattgat tgacgaatta gggattccgt tggatgaata
     9061 cttacgtcgt tgtgaacaac aaattaatga ttgggaaagc atgcgagagg acattgtaaa
     9121 taatggggag ttaacacata cgagaagccg tgaatatgct tcatatatca tggattctat
     9181 tacgacagga actccgtcag tgattgcagg aaatgtctta aataaaggct taatcacaaa
     9241 cttaccgaca gatgtttgtg tggaagtacc ttgtttagtc gataaaaatg gcgtgcaacc
     9301 aacctatgtc ggtgaattgc caacacaatt agctgcttta aatcggacga atatcaatgt
     9361 tcaagaactg acagtagaag ccgctttaac actagataaa tcaaaaattt atcaagcagc
     9421 gtatttagat ccacatctat catctgaatt gtctttaaca gatatcaaaa atttagtgga
     9481 tgatttaatc gaagcacatg gggactattt acctgaatat aattaaaaag aagctgaaag
     9541 agtaaggaat tttcaattcc ttactctttt cttagttaaa tttagtaaaa atattgacaa
     9601 aacacttagt aaacagttac attagtgtta acaaaaagaa aacgcattca aattgtataa
     9661 ggaggagcat aaaatgaagt ggtctaaaaa aattatttta gcttgtatag cactaggagc
     9721 aacgatctct ttgactgctt gtggaaaaaa tcaggaagat gcaagcggta aggtagaaat
     9781 agagtttttt aatcaaaaaa aagaaatgac tcaaacgatt caggagattg ctaaagattt
     9841 tgaagcaaaa aaccctgata ttcatgtaaa agttgtggat gtaccgaatg ctggtgaagt
     9901 aattaaaaca cgtatgcttg caggcgatgt accagatgtc attaatcttt atcctcaaag
     9961 tatagaattg aaagaatggg cgaaagctgg ttatttagag gacttaaccg aagaaccgta
    10021 tttagagaat atcaaaaatg gatatgcaca acgttttgct attgaggatc gtgtatatag
    10081 cataccatta accgctaatg tctatggttt ttactataac aaaactgctt ttgaggaaat
    10141 ggggattcaa gcaccagaaa cttgggcaga atttgaaaaa atagtagctg agattaaaga
    10201 tcaaaacaaa gtaccgtttg cgattgcagg agcagaaggc tggactttaa atggttatca
    10261 ccaactagct atagcgactg ctgctggtgg tgaagaggaa gcgaacaatg tttggcgttt
    10321 ctcagaagtt aatggaatta atgctgaaag caaagaaatg caaaaagatt ttaatcgatt
    10381 agatttgtta agagaaccaa aagctttgca aaacaactgg caaggtgccg gttataacga
    10441 tacagtagtt acttttacaa aaggtgatgc gttgattatg ccgaatggtt catgggcaat
    10501 gccgatgatt cattcacaaa atccagattt tgaagtagga acttttcctt ttccagcaga
    10561 tgaagcaggt caaagtctaa cgattggcgc aggagaccta gccttatcag tttctgcaac
    10621 ttctcaacat aaagaagaag ccaaacgttt tgtagaatat atgacaacac ctgaagcgat
    10681 gcagaaatat tatgatgtag atggtgcacc gtgtgctgtt gagggcgtta tcgagaatac
    10741 tcaggattca ccattaagtg gtttaactga acttgctttt actgatcgtc atttagtttg
    10801 gttagccaaa gattggaata gtgaaaatga tttttatacc ttaacaacaa attatttaca
    10861 caatggcaat caaaaagcca tgattaacgc attaaatgct ttctttaatc caatgaaagc
    10921 tgacggaagg taggaaaata aaatgaaaat aaaagaaatt ttaaatcgtt actgggcaat
    10981 catttttgta gcaattccaa ttattttgca gatgattttt ttctactttc caatggttca
    11041 aggtgctttt tacagtttaa ctaattggac tggtctgact tataattttg attttgtggg
    11101 tttgaacaat tataagattc ttttttctga tccgaagttt atcaaatcga ttggcttcac
    11161 tttaattgtg acgctttgca tgattgctgg acaaattggt tttggtattt tgattgcgcg
    11221 ggcgttgaac gcaaatatta aagggaaaac attctttaga gcatggttct tttttccagc
    11281 ggtcttatcg ggcgtggttg tttctttagt atttaaacaa atttttaact atggtttacc
    11341 aaaaattggt agtatgttag gcattgaatt tttacaaacc agtcttttag gaacaacatg
    11401 gggagcgatt tttgcagtaa tttttgtttt actttggcaa ggaattgcca tgccagtcat
    11461 cattttctta gcgggttttc aaagtattcc acaagaaatt attgaagctg ctagaatgga
    11521 tggggcgaat gataagcaaa ttttttggaa tattgaaatc acctacttat taccaagtat
    11581 ttcaatggta tttattatgg cattaaaagg tggcttaaca gcatttgatc aaatttttgc
    11641 tttaactggt ggtggaccaa gcgatgccac aacatctttg gggttacttg tttataatta
    11701 tgcttttaaa aacaatcagt ttggttatgc gaatgctatt gctttagtct tatttatctt
    11761 aattgggatt gtttcactgg cacaattaaa attatcgaaa aaatttgaaa tctaggaggt
    11821 ttcccaatga aaacatcaaa agaaaaaaat atttctaaat acttgctttt attattaggg
    11881 ggcttcatga ttttagttcc cttagtttca acgctattcg gttcatttaa aacaacaccc
    11941 gatattatga ataatttctt tcgttttcct aatccagcga ctttggaaaa tttccgaaga
    12001 ttgttagcgg atggaattgg tcattacttt tggaattcgg caatcatcac aatcattgca
    12061 gtagttgctg tgacagcaat tattcctatg gctgcttatt cactagcaag aaaaatgact
    12121 cgtgggaaag catacggatt gatgtattta tttttaattt taggaatttt tgttcctttc
    12181 caagtaatta tgattccgat taccgttatg atgagtaaaa ttggtttagc aaatatgtgg
    12241 ggattaatct tactctatct cacttatgcc gtaccacaga cactattttt atatgttggt
    12301 tttattaaac taaatgtgcc tatcagtctg gatgaggctg ctgaaattga tggggctagt
    12361 cactttacaa cttatttcaa aattgttttc ccaatgttaa aaccaatgca tgcgacgact
    12421 attattctta atgctctatg gttttggaat gatttcatgc taccattatt aattttaaat
    12481 cgtgattcta atatgtggac actaccattg tttcaatata attatacggg acaatatttt
    12541 aacgactatg gtccaagttt tgcttcctat acagtaggaa ttgtcacgat tacactagtt
    12601 tatcttgctt tccaaagaag tattatagct ggaatgagca atggagcagt gaaataacca
    12661 ataaattatt ctcattataa aggagttcat aaacttatga ttatatttga caatcacaca
    12721 caaacatttc atttacaaaa taaaaaaatt agctatctat taggaatcga agaaaataat
    12781 tatttaacgc atctttattt tggaaaaaag attacgcact attctggtgg gtatcgctac
    12841 ccccgaacag atcgttcctt ctcacccaac aatgcaaatg cgcaagatcg tttattatct
    12901 ttagacacat taccattaga atttccagga tatggacatg gtgattttag agaaccggcg
    12961 cataatatta aattaggaaa cggtagtcgt gtaaatgatt ttcgttatga tagctacgaa
    13021 attcaaaaag gaaagcccag cttagcggga ttgccagcct tatatacgga agatgatgat
    13081 gaagctgaaa cgctgattat tcaattgaaa gacgcgatta gtggattgac tttacagttg
    13141 ttctacacaa tttatcaaaa tcacagtgta attattcgtt ctacgcaatt agtaaataat
    13201 agtgatgaaa cagtggagat taaccgctta gctagtcaat caattgattt tccaaatcgt
    13261 ccactcgagt taattcattt aaatggtacc tgggcaagag aacgtcaaat gactagagaa
    13321 aaaattcata cagggataaa agtattagat agtaaacgcg gatcaagcag ccatcaacaa
    13381 aatccgtttg ttgctttagt agatgccaaa acagatgaat ttcaaggaga ggcatatgga
    13441 tttaatttag tttatagcgg taatcacgaa acggtgattc aaaaagatcc atttgaccaa
    13501 acacgggtca ttatgggaat taattcattt aattttggtt ggcaactaaa aactggcgac
    13561 tcatttcaaa cgccagaagt cgtgatggtt tatagtaatg aaggtctgaa tacgttatca
    13621 cagacgtatc atgaattgta taatcaccgt ttaattcgtg gaaactatcg tttaaaagaa
    13681 cgtcccacgt taatcaacaa ctgggaagca acgtattttg attttaacga agaaaaaatc
    13741 atgaatattg tcgatgatgc gaagaacttg ggcattgaaa tgtttgtttt agatgatggt
    13801 tggtttggcg gtcgtgaaaa tgacttcact tcattaggtg attgggttga aacagaaggc
    13861 aaacttgctt gtggtttgga aaatttagcc aagcaagtgc atgataacgg gatgaaattt
    13921 gggatttggt ttgaaccgga aatgatttct gaagatagtg aactatttcg agcacatcca
    13981 gattgggcat tgggtattcc aggtcgtgac cgctcaatta gtcgaaatca atatgttctt
    14041 gatttttcaa gacaagatgt tcgtgataat atctatcaac aaatgacggc gatttttgat
    14101 cgtgtaccga ttgattatgt gaagtgggat atgaatcgaa atatgacaga agtctattct
    14161 gtcttgttgg actcaacgat gcaaggtgaa gtggctcatc gttatatgtt agggttatat
    14221 gaatttttag aaaagttaac aacgaattat ccaactattt tatttgaaag ttgttcgggt
    14281 ggaggcggtc gttttgatgc aggtttcttg tattacatgc cacaaacttg gacgagcgac
    14341 aataccgatg ccgtggctcg tctgaaaatt caatatggaa ccagcttagt gtatccaatt
    14401 tcaagtatgg gtgcgcatgt ttcagcagtc ccaaatcatc aaacaggaag agaaacgagt
    14461 ttaactattc gtggcaatgc tgcgatggct ggtgtttttg gttatgagct agatctaacg
    14521 caattaactt ctgaagaaaa agcagaaatt aaagaacaag ttgcctttta taaaaagcat
    14581 cgccaacttt tgcaatatgg aactttttat cgcttggaaa gtccgtttga aggcaatgat
    14641 actgcatgga tgtttgtctc aaaagaccaa acagaagcca tggtctttta tttccgagta
    14701 ttagcagaag ctgcgcatcc attagtcaca ttgaaattag caggattagc agaagaagca
    14761 acttatcaaa tggaagatgt aacatttgct ggcgatgaat tgatgaatct cggtttttat
    14821 attgactcag aactacatgg tgattatgcg acacaacgct tttatttgaa acagatatag
    14881 tagcttgaat ttacaatata agtgcaacac caaaagagac tcattccaaa cgaagaaaat
    14941 atgttttatt tacacgcatt tactaaaaag cagcctgatt tgaattggga aaatgaagaa
    15001 gtacgtgaag aaatctatgc aatgattaac tattggttag ataaaggact aggcggattt
    15061 agaatcgatg cgatattaaa catcaaaaaa aaactagagt atggcatctt tgaatctgat
    15121 ggagaagatg ggttagcctt cattgggccc tggattctta atcagtcggg cattgaagtg
    15181 tggttaaaag aaatgagaga gcggacattt aaaccacata atagtatgac ggtagcagaa
    15241 gccgatgttc ctaatgaacg tttagatgaa tatattggtg aagatggcta ttattcgatg
    15301 gtttttgatt ttagttatac ggatattgat gtacctgaaa ctggtgaatg gtttaaagat
    15361 agccaatgga catggacgga tatgcgtacc aatattttta cgaatcaatt agttacgcaa
    15421 gataaaggtt ggggcgcctt atatttagaa aaccacgatc aaccacgttc aattaataaa
    15481 tatattccag aagaatggat caatgattat agtaaaaaaa tgttggcgac gctttttatg
    15541 ttactaagag gtaccccttt tatttatcaa ggacaagaac taggaatgac caacatagaa
    15601 atggcatcat tagaagattt tgatgatgta gctacgcatt ctcagtataa acgggcatta
    15661 gaatatggat tggcaccaga gcaagcattg aaagctgtca ataaacgaag tcgggataat
    15721 tctcgcacac ctatgcaatg gaatacgcaa aaaaatgcca gattctcaac ttctgataat
    15781 gtatggttaa aagtaaatcc taattatcca gaactcaatg cagaagctca gttaaccaat
    15841 caacagtcgg tattcaatta ttatcatcaa ttaattaaat taagaaaaaa tagtgtatac
    15901 aaagacgtgc taatctacgg acaatttcta ccagtgaaag ataaaaatga acatattttg
    15961 ctttatgaac gccaattaga agataaaatc gtattagtta tcttaaacgt tacagcaaca
    16021 gaacaagaat attatgtaga tgaacagtac caacaagtat taatcaataa ttatgaagat
    16081 gttttattag atcaaagtcg aaaattgcgt ttacgaccgt ttgaaagtat tgtattagct
    16141 aattatggag gacaattatg aaaattaaaa acgaagcaat gctcatcacc tatgcagata
    16201 gtttaggaaa aaacatgggc gaattaaaac aagtcttaga caaacattta caaggtgtta
    16261 ttggtggtgt acatctgttg cctttttttc catcgacagg tgatcgaggc tttgcgccga
    16321 gtgattatac gacagttgat ccagctcttg gaacatggga agatgtggaa gcattaggtg
    16381 aagattatta tttgatgttt gattttatga ttaatcacat ttctcgtgaa tcaaaatttt
    16441 tccaagattt caaaaaaaac catgagcagt caccatacaa agaaatgttt atccgtattc
    16501 atgaattttt cccagaaaat cgaccaacac aagaagatat tgatttaatc tacaagcgta
    16561 aagacaaagc gccgtttcaa acggtagaat ttgcggatgg tacgacagaa gaggtttgga
    16621 atacctttgg ggaagaacaa attgatttag atgtgaccaa agaagttgtg aaagaattta
    16681 ttcgagaaac catcaaagat atggcgaacc atggctgttc tttaattcga ttagatgcgt
    16741 ttgcttatgc gattaaaaaa ttagatacca atgatttctt cgtggaacca gatatttggg
    16801 aacttttaga cgaagtgcgt caagaagcag cgaaatatga cgtcgaatta ttaccagaaa
    16861 tccatgagca ttattccatt caaatgaaaa ttgccaatca tgattattat atctatgact
    16921 tcgccttgcc aatggtcact ctgtattcac tttatagtgg aaaatcagaa cgtttagcca
    16981 attggttgaa aatgagtccg atgaagcagt ttacaacatt ggatacgcat gatggaattg
    17041 gtgttgtgga cgctcgtgat ttattaacag atgaagaatt ggattacacc tctgaggaat
    17101 tgtataaagt cggggcgaat gtgaagaagg tctattcaag tgccaattac aataatttag
    17161 atatttatca aattaacagc acctattata gtgcattagg cgataatgac cgtagctatc
    17221 tgttagcacg tgcgattcaa gtatttgcgc cagggattcc acaaatttat tacgttgggt
    17281 tattagcagg aaaaaatgat attgaactgt tggaagcaac gaaagaaggg cgtaatatta
    17341 atcgtcatta ctatgattta gccgaaattg aagaagaagt gcaacggcca gtgattcaac
    17401 aattatttgc acttttaaaa tttagaaatg aatctgcggc gtttgatttg gatggaacga
    17461 ttgaagtagc aacgccatca gaatcagaaa tagtgattac acgtaaaaat aaaaacggta
    17521 gtgatagtgc aacattaacg gctaacttgg atacgaaaga atttatcatt gagtctaaag
    17581 atataaaaat tttcactagt gttgcattaa aattttaacc tattccatag aacaaaaaat
    17641 cctttatact agcacttgga tgacttatcc aagaccaata aaaaggactc atacatggat
    17701 aagtataaaa caaatacagc atttaataaa tggttttctg ccataaaatt aggaaaactt
    17761 tctgtcaact cccaaaaatg tatttttgat tacaattcgt atcgtaaaaa actgtctttt
    17821 gaagctgtgc tcaagctctt tctctacgca gttaatgaag aaaaagaaag tttgcgtgat
    17881 ttgagtacag ctcttatcga ccgatcgctc caactagaaa ccgatgtgtc atcgattagt
    17941 catacccaat tgtctcgagc atttaatgca cttgaaccta aagtgttaga agaaattttt
    18001 caacaactgt tagaaaaagt tcaacatcaa atcaaaccaa ccaagcgaaa tcatctgtat
    18061 ctgattgatt ccagtacgtt ttcgcttagt ttaaaacgtc ataagtgggc gactttccgt
    18121 caaacaaaat caggtgtcaa gttacactta aactattgtt atatggacga tactacgatg
    18181 tatccaactg attttacctt aacaaatgcc catgaacatg atctcaatca actaccagta
    18241 ttggtgaatc aaccagaggc aacttacgtg tttgatcgtg ggtattagga ctttgaaaag
    18301 atggatcaga tgcattggga tggctatttc ttcgtcactc ggattaaaaa aaacaccaaa
    18361 gttcacgtga tagatactct ggaaacatcg ccagaaacag aaattctacg agacgagctg
    18421 gttcgtttag gatctaaaac ctatctaacc gccaatttcc gactagtcac tgttcaagat
    18481 aagaacggac gtgtgtttca atttatcacc aatcgaatgg acgtctcttc aaaagaaatc
    18541 tctgatatgt atcacgctcg ttggcaaatc gaattgtttt tcaagcacat caaacaacac
    18601 atgaccatta aaaccttctt ttctcaaagt gaaaaaggcg tgcagaatca attgatttta
    18661 acgatgattt ccgctctcct cacgtttctc atcaaattgg agacgaaaac ggaaaaatca
    18721 gtgttccaaa tcaaacgatt ctttcgttat ttactgtttc agccctttga atgttgtcta
    18781 gaaaaattaa ttcccacatg agaaaaaaga aatttggctc gttacttttg gttttcagtt
    18841 gaataacaga taaaaaattt tctggaaaaa gtcatcctct gcgtcagcac agtttttttt
    18901 gacttatttt cagaggaaat agttttcaga atattctaaa atgttttatg caacactagt
    18961 gatatttttt agaattagat ttctaatgtg cattttttga gtattaagga gcaagtatac
    19021 aaagatttat aaagctgatt aaatttgaat aaaaatatgc aggaacgcta ctatttttag
    19081 tagtgttctt ttttatattt gaataaaaaa tgtggtggtt aaatggtggt tataacaaaa
    19141 aatgaattaa tgaaattagg ttatgggaag tatcagtctg agagaatcat acgacaggca
    19201 aaagcaatta tggtttcaaa aagctatacc tattacgaaa atagaagatt aggactagta
    19261 cctgttgaat ctgtagaaga agttttaggt atgaagatag aggtagagga ggattttcag
    19321 aatcatggtt aattttaaaa aagataaaaa tgggaaatat cattttactg ctagtttggg
    19381 attcgacaaa cgaacaggga aaagagtaca aaaaaacgta gaggggttaa aacagttaaa
    19441 gaagaaaaaa agcgtatacc gaacttgttt ctaattatgg aaaagaagca gaaacttctc
    19501 aaagtactat gttgtttgag gagttttttt ataaattatt cctaccttat tatcaaggga
    19561 aagtagaaga aagaacatat aaaaatcggt tatctacaat caaaaaaact tttcttattt
    19621 ctttaaaatg gagttaagag aaatacgtcc aattgacatt caaaagtggc aaaataattt
    19681 attgagcaaa tataaaaatt cttatgtaag aaacatgtat gggatttttc agatgtcatt
    19741 agatcgagca gttgttttgg gactacttga aaaaaatcct gcaaaagtta ttggaaatgt
    19801 gaagaaaagg aaaactacag ttgatttttg gacaaaagaa gaatttacaa aagttatttc
    19861 aactttttat attgatgatt tgtaccaaca ttttggtttt atttgtatgt ggttactttt
    19921 tatgaccgtt atgcgtttgg gagaagccac tgcattaact tggaaagata ttgattttga
    19981 aaataaaaac ttgcgtgtga ataaaacact ctattataag agagccaaaa cctatgagtt
    20041 tgtagaaccc gaaacggctt ctagtattcg tacaatcgaa ctagacgaca atacaattac
    20101 ctttttaaaa gcttggaagg agcgtcaagt ttcaatagga ggcatgtcgt ttgtactttc
    20161 ttataatgga acacctactc agaaatatac aatccgtcat attatgagaa gacatgcaac
    20221 gatcgttggt gttcatataa tccgcataca cggattaagg catagtcatg cttctttgct
    20281 tatatcacaa taaaaagatg cacttcgaat taaagaaagg ttaaaacatg ctgatgtaca
    20341 aacgacttta ggaacttatg gtcatttgta tctaaattca ttgagagaga taacaaatga
    20401 tcccacagat tatatccaaa ctaatttttc taaaatcaaa ccgacaccta tttacgataa
    20461 taaaaaataa atgataaaca aaagtaggat cacaccaaaa gaaacacact agaaaaacta
    20521 taatacaggc ttttctagcg tgttgtttct tatttccgcc tatttataca ttatactcat
    20581 aaagcattta atgcatcgat cgtagccgca ttgtctatat gggtatataa agttgttgta
    20641 ttggtacttg aatgtcccaa ttgttgggca gttaatacca atgaatttgt ctgttggtag
    20701 agtctagtag ctaatgtatg acgcagtttg tgagggctga cttgaattct aaagcctttt
    20761 gaatattttg ctaccatccg ttcgattgca ataccggata tacgcttggc ttctccttgg
    20821 taaattgcta gaaataaagc tttttcgttt tctgttactt tatatcgttc tttccgaata
    20881 gctagataat tagctaaata ttccattgcg aatgctgcta tattgacagc atctctttta
    20941 tttccttttc tagttactac cacattattc ttatctaaag ataggtcatc taaattaata
    21001 tttataacct cggagagtct caatccagat cctaaaatca gtgcattgat cgccaggtct
    21061 ctttctacat ctcgttgata atagatcaaa gctcgtttac tcaaagtatt tttatattca
    21121 ttggcaatat aatctagata attttgtgta tccttatcta gaaataattt tttctcaatg
    21181 gcattggcac gtgcagctaa cgtagtttta tctgtgatgg ttgctacttg atccatagga
    21241 ttattgtcta agtatggttt tcctagagga ttattggaac ttttcgaaag atatttaaat
    21301 agaaccttta atgccgtgat atttctattg atagtagaag tagatagacc taagttatta
    21361 ttatctttga gcttagtttt tgttgtctct ttttttacat tttcttttgt gcgacgtttc
    21421 aaatgagatt tgtacaagtt taggtcatag gcagttaact gtcttatcga ggtgatagaa
    21481 gtatcaggaa cgatagactc actcagaagc cattcataaa agagcttata attttttaga
    21541 tattctaaag tggttcgagg tgattgatct ttatcctcac gatcttgaac aaaatctttt
    21601 atataatcgg gcatatgaag tatgattgta tctatttttt gatatatttc tgtatttttc
    21661 atgtcattca tcctttcaat aagtagggga gaagagtatc tctataattg gactatacca
    21721 attatagaat gttttgtcaa ttggtatgct ctaaaattta ttaatttgtt tcaaaaaaag
    21781 catataaaca ggtatacgtt taataattta aaataaatgg tatacataaa tagggaagga
    21841 aatagaaggg agcaatctaa attttttgaa ttttcttaat taattatata gaaagaacaa
    21901 tctttctata gagttagaca tgagagggac tatgcttgat ttaaaatcaa caagcgtata
    21961 tactgtatat acaaagaaaa aggagggaga agactatggc aattaaagaa agaaaattta
    22021 gggaagtggg gaactcagta gtattaacta tttcaaagga gtttcttaaa gaaaatgggt
    22081 taaatcccgg agatacggtt tttttagatg aagaaaaact tcgagcggca attacaaaaa
    22141 aacaagcctt atctgatgaa attgatttag caatatctca agcattaact gaatatgata
    22201 ctacttttag agagcttgtc gataaatgag tattcattac ctagaagcca aagatattat
    22261 aaaaatgaat gtaatccaaa taaaaaaata ctctcctaat gaaccccttg gtgtaaagga
    22321 tgcgaatgct ttagaaatgt gtgtagggca acttcgagcc tcagcttttg gtgaagaggt
    22381 ttatccttcg atttatgaaa aagcagctat cctacttata caattgataa agaaacatcc
    22441 ttttcacaat gcaaataaac gtactgcttt cttagctact tttgtctttt tgaaaatcaa
    22501 tggacagctt ttagctattg atcaaaaaga tgctgtaaat ttagcggtat atattgctac
    22561 gtatgataag gatttcgatc aactaaaata tgaagtgatc aacactataa agacacatac
    22621 gcagcccatt taaggagtta ctgtatgtgt ctttataggg ttattagctg ctatagcgaa
    22681 ataattgaag taaattacaa atagctataa ttcaaatcca actatataga aaacgtaaat
    22741 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
    22801 atacttttac ttggtatatt tatgaataa
//
LOCUS       DARBDN010000036        22180 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000036 DARBDN010000000
VERSION     DARBDN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22180
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.036"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..144
                     /locus_tag="SCH06_001389"
     CDS             <1..144
                     /locus_tag="SCH06_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1077974.1"
                     /translation="DFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYS
                     SLI"
     gene            complement(215..1525)
                     /locus_tag="SCH06_001390"
     CDS             complement(215..1525)
                     /locus_tag="SCH06_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEG1077975.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1537..2955)
                     /locus_tag="SCH06_001391"
     CDS             complement(1537..2955)
                     /locus_tag="SCH06_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1077976.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3195..4763)
                     /locus_tag="SCH06_001392"
     CDS             complement(3195..4763)
                     /locus_tag="SCH06_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEG1077977.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4767..5048)
                     /locus_tag="SCH06_001393"
     CDS             complement(4767..5048)
                     /locus_tag="SCH06_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEG1077978.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(5045..5968)
                     /locus_tag="SCH06_001394"
     CDS             complement(5045..5968)
                     /locus_tag="SCH06_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HEG1077979.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5965..6843)
                     /locus_tag="SCH06_001395"
     CDS             complement(5965..6843)
                     /locus_tag="SCH06_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HEG1077980.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6830..8167)
                     /locus_tag="SCH06_001396"
     CDS             complement(6830..8167)
                     /locus_tag="SCH06_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEG1077981.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8170..9273)
                     /locus_tag="SCH06_001397"
     CDS             complement(8170..9273)
                     /locus_tag="SCH06_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEG1077982.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9347..10855)
                     /locus_tag="SCH06_001398"
     CDS             complement(9347..10855)
                     /locus_tag="SCH06_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEG1077983.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10821..11513)
                     /locus_tag="SCH06_001399"
     CDS             complement(10821..11513)
                     /locus_tag="SCH06_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEG1077984.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11535..12509)
                     /locus_tag="SCH06_001400"
     CDS             complement(11535..12509)
                     /locus_tag="SCH06_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1077985.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12809..13681
                     /locus_tag="SCH06_001401"
     CDS             12809..13681
                     /locus_tag="SCH06_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1077986.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14263..16461)
                     /locus_tag="SCH06_001402"
     CDS             complement(14263..16461)
                     /locus_tag="SCH06_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1077987.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16693..17685
                     /locus_tag="SCH06_001403"
     CDS             16693..17685
                     /locus_tag="SCH06_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1077988.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17745..19166
                     /locus_tag="SCH06_001404"
     CDS             17745..19166
                     /locus_tag="SCH06_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HEG1077989.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19159..20658
                     /locus_tag="SCH06_001405"
     CDS             19159..20658
                     /locus_tag="SCH06_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HEG1077990.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20697..22091
                     /gene="uxaC"
                     /locus_tag="SCH06_001406"
     CDS             20697..22091
                     /gene="uxaC"
                     /locus_tag="SCH06_001406"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEG1077991.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6729 a         4518 c         3843 g         7090 t
ORIGIN      
        1 gattttagaa aagtgaatca gacatttatt tccagtgtca gcaatcaacg taatcatatt
       61 ccaagaaaat cattgaatta cagaacacca atcgaaatat ttttgagcta tgtacaagaa
      121 gcattttatt ctagcttaat ttgacaaatc atatatcatt aaaaaaaata aaggtcaagc
      181 taaaatatta tttaagcttg accttattat aatttcaacg attgtcaaaa gtattgtttg
      241 cagctgtgtt gccagtttct atagataaat cacagctttt gaaacataag ttttgtactg
      301 cttcgattcg cccgaattct tttgcagtta tttggcaatg agaaaagcag acatcttcta
      361 taggcttttc aggaaatgct actaaatcaa aagctcggga aggaagtgag taacctggag
      421 aaaggcatgc ctgtacgttt ttgatgtgta tgtctttgac tttcgtcatt tgctttgatt
      481 caggtatttc ttcagccact gcttgccaac tttctggcat ttgagcaagg tcattgctat
      541 tttttctatt gtattcatta tgccagtcca ttatccaaga aaaaggaaat tgtacatcaa
      601 tcatattcag attttctacc ctgatatttt cgatcactcc ccctctttct tttgaagatt
      661 tcattcgaat accacagtct gactgaaaaa aattgatatc gtgaatatat acgtcactaa
      721 ctccagcact aacttcgcta ccaatagtta caccgtatcc tgaacggatt ttacatctag
      781 caacctcgat tcttgatgat tttcgattga ctcttgcacc attgccatct ctgccagact
      841 taatagcaat acaatcatca ccacaggcca aatcacattc atagacacgc acatttgttg
      901 aagaatcaat atcaatccca tctgtacttg gtccatcatt gttgcggatg attacttttt
      961 ctactaatac atcgttagaa taagtgattt gcaagttcca aaaacctgat ttctgaaaaa
     1021 tcaaatcacg aacaacaaca tgttctgcat gatacagtaa acaagcgcgt ggacgtttaa
     1081 tagcataatc cgcaatccaa cgaagtccct tttgatcgta ttcagctctt gtcccgcttt
     1141 tttgatcttt tccccaatac agctcccacc aatggtctcc ttgaccgtcg attattcctt
     1201 ttccttctat aagaatatct ttcgccgaga gaacattcaa aatcgctgct ggccatttca
     1261 tttctacgcc ggctactcgt gtatcgattt ctggaaatgc ttcgatatct gttctcccct
     1321 tgaggactgc accttcttca aagataagat gactcttatc ttttaaaaaa agggctccga
     1381 ctaaataaat gccttttgga ataaatacag gtaagtgttc tttcgcacct tgatcgattg
     1441 ctttttgcag tattattgta tcatcttgtt gagtgtcgtt tgttttaaag ttcaaagcat
     1501 tgataatccc tttttttgtc cgcaatacgt ttctccctat ctttcattga tttttttcaa
     1561 ttcttcacca ataaatacag tttttgaacg attcagtggg taacctacta gcaaaatgat
     1621 tgcggataca aataagcaga atgctggtaa caagtttgcc atcgtataaa tcctttcttg
     1681 tactaaaact gattggatgg ctccacctgt tgtagacgat tggtaaccaa tgagtgccag
     1741 cataaatccg cctaccgctc ctgcacatgc ttgtcctact tttctcgcaa aagaatttac
     1801 tccatatact gttccatctt ctcttaagcc tgtcttatat tgatgataat caatcacgtc
     1861 agtaatgaat gcccagacca tcaaattgaa taaaccagat cctaaagtag cgataaataa
     1921 aagaatcaga tatacccatg catttgttat atgaaggaaa tacatcagca agtacataca
     1981 tgaagaagca agtaacgcaa atacgcttgc ttccttttta ccaaataatt ttgtcagctt
     2041 tgtagcaaat ggtgctaaaa ctactactgt tccgtaagta aataaaagag caacagacat
     2101 tgcttgttta ttatggaagt aatcattgaa taaataagtc atattcgtcc cagctaaaat
     2161 ctgattgatc acaatgaaaa tgtcaacaat gactaaaata atcagtgctc gattagctaa
     2221 caaacctttt accaactgag aagcagatac tttttcgttt ttgacaactc ttactctttc
     2281 agtagtcaat ttacaagtta acatatatgc gacaaatgct attgcagcac atccgattga
     2341 aatccaaaag aaatgattcc ctgaaacgac ttgttgtcca ctcttgttat gggtatacat
     2401 taaaatcgga atgaagaatc ctgtagttga tccgccaatc gcagaaccaa tgcttcggaa
     2461 cgtggacaac gaggtgcggt cattaggatt tgagctaatt gctgctgcca ttgctccata
     2521 cgggatattg attgttgaga gaaaaatccc ataaacaatg tatgaaacaa aaatataagc
     2581 aatcttcacc gtcattggaa gatgttggac gaatggcaaa aacaaaatga cagtcactaa
     2641 gcaaaatgga tacttcattt ttctgatcca aggaataaat cggccagttt ctgttaactc
     2701 tgagacatca cataatcttc caaccatcac atcagcaaac gcatccaaaa ttctcgaaat
     2761 caagaataac gtacctacga ttgcccctga aacgccaaga acattcgtat aataaatcat
     2821 caagaaacta ttgactaaac ctaaaataaa acagttacct agatcaccga acatgtagcc
     2881 tatcttatcg gaaatcccaa attccttttt ttcttttttt actgtatttg ctgtaacagc
     2941 attttgtgaa agcatttgaa ttcctcctac ctcttctagt aaacgttttc aaaattataa
     3001 ctcttttttt cttgttttta tattcacaat gttggctttt tattgcatta tcttgacaga
     3061 taaaaaacaa aaaataatct aaaaacattg atgcataaga ttgataactt tttttacata
     3121 acaatatata caaacaaaaa aattcactaa ctagtgaaaa taagttagtg aacctcattt
     3181 attaaagaat taaattacag atgatctttt ccatcatact tgaaaaactc aaaatcagca
     3241 taacttcctc tttttttatt tagatcatgc actgctatcc cgataaaatt tccagtaaac
     3301 cctcctgaga gtatacacat gtttttttgc ggacctactt tcttccattc ttcagttgat
     3361 acgtctttca aatgaaactg tgctgtctct ttctttacag tgactttcaa aaaagtcttc
     3421 ttttctgtga gtggaatcgt ccaatcttct atttgtgcta ctccgttttc tgattctatc
     3481 atacgtaggc attttccctt gtcctcattc caagtaacat aacaataaat ataattggat
     3541 tcatttaagt acagtaccag tccagccatc tgattaaaat tattaggcat gtattcaaat
     3601 gctgtctccg catcaaaagt aaaatccgtt tgccgaatag ctaacaaatg atgttcgaag
     3661 gtagattgaa gagattcacc ggaaatcaga cgtaaaaaac ctggtctaca ttttgtatca
     3721 caccaatcag catttggcaa aatgcgtctg gcattccagt tcttctttag ctctccttca
     3781 aatgtatcca taaactgatg atctttttct tgttgtacct cttcatttgt ctcaatcatt
     3841 atttcttcca tcggagttgt ctggctatct ttaagtctta accaatcgtc ggacgtccaa
     3901 tacacttctt gaatagcggt ttctcttccc aaaatagccg caccgtttaa tggtctggta
     3961 caaagatatg tcatgtacca tcttcctgac ggggtttgta ctaagctccc atgtcctgta
     4021 cattgcaatg tagaagcagg tttgtcacta gctgtcagca taggaaaacc aggatcaagc
     4081 tcgtaaggac cagtaatatt ctttgctcgg caaactgtaa ctgaatgtcc tcttcctgta
     4141 ccgccttctg ccgtcatcaa ataataatac ccgttacgaa aatacaaatg tggtgcctcc
     4201 gttttcgcta attctgtacc tgcaaatatt ttatagatgg gaccatcaag cttcttcttc
     4261 tctgcatcat attcttgtaa tacgataccg ctggatttat tcggtgtgtc cagacgataa
     4321 tcccatagtt cattgacaag ccattttttt cccgtttcaa gatcatggaa caaagaagga
     4381 tcaaagccgt tactatttaa ataaattggt tcggaccaag gacctgtgat ctcagatgca
     4441 gtgatcaaat aattgtggac atctttaaac ggacggcctg cacttttgac atctgtgtaa
     4501 acaagataaa acaatccatc agcataactg atctgtggcg cccatatact tccatttgta
     4561 ggatttcctt gcaaagatac ttgagtggtc aaaatatccg ttgtatgtga ccagttgact
     4621 aaatttttcg actcatatac tcggattcct ggaagccatt caaaagagga gacaataatg
     4681 taataccgct ctttcactct taatatatta ggatctggat tgaatcctct taaaatagga
     4741 tttttcactt tgatagtctg catgattcag gctccttttc tcattcttac tcgatataaa
     4801 ctgaatgccc cagctgctaa aaaagcaagt gaaataaaca acacaacggc aaacagacca
     4861 gtcatgtcct gtaataatcc aaatgtattt tctaaagaca aagttgaatg atctacagca
     4921 agcgactgat aacttttttt aaactctgac gcagacatat tacttaaagt aactgctaac
     4981 ccgccaaaga aaatcaaaga tagactgcca ccgaccattc ctagcaatag ttcccatttt
     5041 cttttcattt ctgaaccccc tgcttttcta aatgtatcca ttcaggtctt ttgatcgatg
     5101 tttcataatt gttattacgt tcagagaatt tgacagtctg ttcatttttc ttgtcatccc
     5161 aattatccca accagttggg tgaacatgcc cacctatctt acacgcttca aataagacat
     5221 ttgcatacgg acgccacggt cttcctaaat agacgtttct agtatcaggt tctgcagtca
     5281 aggtacagct ttcaaaacga taccctgttt tttgattttt cggcgtagat gctgctgtga
     5341 tgtatccagg atttttactg gctaagctat ggatatgaca ctgatgaaaa acggcatctg
     5401 ccccaccaaa tatgaaatcc accgttcctt caatccagca atattcatag gtctgacgac
     5461 aatactcagg attggcagaa gccggtgtac aaaaaggagt accatctttt tgcaaatcag
     5521 gcaacggacc cgtgcataag gtatcctgat aaccagatag tcgacagttt tttaaagata
     5581 cgcgatctcc tgaattgaat aaagcaacag cctgtcctac cttttctcct ggacctgctg
     5641 tattttcgat gtgaagattt tctaatacga cattcgatcc ttctaagaaa aaagtagcac
     5701 ttcggaaagt ccctaactgg ctaccgtcaa gatactcctg ttttgcaaaa cgattaccgg
     5761 agataactac tgttcctgct cccacaagtt taaaattgga taatctgctt tctatatatt
     5821 catcatatct tccttctttt actatcaaga cctttggatg gctatccggc aggcctgcca
     5881 aataatcgat tccttcttgg atagtttcaa aatccgtcgg ggtatctata gcattctttc
     5941 caattatcag tttgtctttc atcctcataa atgctccctt atgaattgtt tccaaatatt
     6001 tctcatttct tgtgtttcca tatgaccgcc tgttaaagaa aaagaagaaa agttttctgg
     6061 actacccatt gattgatact ttttgtccag cccttttctc agcttcagta cgccttcgtc
     6121 caagcacatc gtatcgtttt ttccaactaa gctaagacga gggcgcggag cgattttttc
     6181 ttggattgct aacgttgtat aagctgtcaa tagatttggc acatagtaat aaaacccatg
     6241 atgatctagg cggcgatgta gcaaaagtgt ttcgatgtcc acctgtgccg ctagatcaat
     6301 acaaactttg acacgagaat ccaatgctgt cacccaccag cttaataagc ctcccataga
     6361 aagaccaatc gttgcgagcc gttgagtatc tgtgtcttcc cttgtctcca aataatcgat
     6421 caagctgatc acatcataaa tacgcattcc ccataacgtt tttcctgtta ataaaaattg
     6481 tttgaacaac tcgctttcag aaatacctcc gcgttcttca aatccccaag catcaatcga
     6541 ccaaacagca tatcccattc ctgtcagtac ttctgcaaaa gatggagaag ctaagtaagg
     6601 agcaccatgg atcaattcac ttttcccgac tgaaaaatct ccgccgtgag aatgcaggta
     6661 aaggaccgtc ggaaacggtc cttctttttc tggataagca tagagggctg gtactgtttc
     6721 caattcattt aagtacaatt gatagtattc aagcataaaa ccgttttgtt tttctcggta
     6781 taatcgtttt ccactagggg tatgtctgct agatggagca cctaaaaaat cattcaactg
     6841 cataagcaaa gtttttacga acaaccagtt catccatatt ttctgattga tttgattgga
     6901 atttctcaat actgatttct ttagtatttt ctaatagaaa tgctggtccc tcgtgatttt
     6961 caatcgacat ctggttaaag gaaaccttac ccgcaaagcc aatataaaat ccttgtctgc
     7021 tcatttcctc tattcctgtc atcatagcag gaacaccggg aactgcatct tgggccatcg
     7081 agacatcgat attgtcaaat gtgatttctt gtatgaattg ttccgctaat ccataaataa
     7141 aacctgcaga agcatggaca ttccttgccg tgatattcga aaaatggatc cttctgaatg
     7201 ctgatgtccg ttcatctatc ggataagcct ttttttccca tacatacggt tctttccctc
     7261 gcggaccaca gaaataataa agattcagta taaatggaca catcacatta tccatgacta
     7321 tattggatac tcgaatatct tcaacgatcc cgcctcgacc tcgtctagat ttcaatcgta
     7381 ttcctcgatc agtttcttgg aagatacaat ttgaaatggt aatattacga atactaccac
     7441 tcatttcact tcctaatacg acaccgccat gtccatggac catcgtgcaa tttgtgatcg
     7501 tgatattttc gcaagcgatc ctttcgtacg tatcttcagt ccctgccttg attgcaatac
     7561 agtcatctcc cacgtcaata tggcaattac taatacgcac atttttgcat gattctggat
     7621 caattccgtc tgtatttggt gaatccgctg ggttcaagat cgtcaagtta tcaaacgttg
     7681 cattactgca aagaatcggg ttgatcgtcc aacttggtga ctggatcaat ttaatatctt
     7741 tcacagtaat tcgatgacag ttatggaaac tcatcaattt aggacgagga taagcgagat
     7801 tatctggttc atttctaaaa gtatgccacc atttttttcc atttccatct aatgtaccga
     7861 aaccagtgac agagatgttc tctacatttt gagcatagat acaggaagca taaacttttc
     7921 gatggactcc ttcccaacgt gaatgaacaa caggataatc ttttggatcg tcagagaatt
     7981 tcagaaccgc tcctgcgctt aaatgaagtt cgacattgct ttttaaaaat aaagctcctg
     8041 ttagaaattc acctgctgga acaactacgg tcccgcctcc gtcacttgct gcagcatcaa
     8101 tggcttgttg tattgcttca gtattcaatt catcaattga tgcgccaaat gtcaaaatat
     8161 catacatatt tataatgcct ccacttcaat caatgcttgc aagaatgcac caacgccttt
     8221 ttgatcatta caaataattg gttcactgat gtagtaagca tatgaaccat ctcgctgatc
     8281 tgctccgcct aaccctgcta cttgacagtt tttattcaag ttcagccagc cttcttttgt
     8341 ttccagaaca aattcatcaa gtaatccttg atgtgatttc ttcacttgtg gaagccattc
     8401 ttctttgttc agcagtccca aacgtattcc tttagccatt gcgtaaacaa acatactact
     8461 gccggaagct tccagataat ttcctttccg ttttgtttct gttgttactt gataccatgt
     8521 cccgctgttt tcttcttgat atggaagtaa tgcagccagt gtcttttcta gaatttcttt
     8581 cagcaaagaa caatctgttt cttcatgaag taattcatag gtatctgctg cagccatcaa
     8641 ataccagcca atcgatcggc tccaaaaatg atgggataga cctgtttttg gatcagccca
     8701 tggttggacc ttcttttcat cccatgcatg aatcagcaaa tttgtttttg gatcgaatag
     8761 atgtttataa ctgatttcaa actgtctcaa aacatcttgg taatcttttt cttcactaaa
     8821 attctggata aattcagcat aaaaaggaga acccatatat aagccatcca accaaatttg
     8881 ataaggataa atttctttat gccaaaaagc tccttcggat gtgcgtggat ggtttgccaa
     8941 ctgctgggaa aggagttctg ctgctttttt atatttttct tcgcctgttt ctttgtacaa
     9001 taaaaagaaa agctttcctg tatttacatg gtcgatattg tattcttcaa cgctgtagcc
     9061 acggatcgtt ccatcttctt gcacgaaata gtcgatattg tcttttatga aatcaaaata
     9121 aattttttct tgggttcgtt cccaaagtaa ttggaaccct ttaagtacga cgccatagtc
     9181 ataagaccat tttcctttat accacttttc ttcatataag cgaggtgttc tttccatgat
     9241 actttttgct aatttctttg accagttttc cattatttgc tctcctttaa aaattaaaat
     9301 aggatttggg acaaatacca agaagtattt gtcccaatcg tctatattac tgtgccgctg
     9361 ctttgtatgc ttcctcgtac tcttgtgtga ttcgatcgcc tccttgtgct ttccagtctt
     9421 ctacagcttt tttgaatcca tcttcgtcaa gctgtcccat gatgtattgc accgtagcat
     9481 caatgacgat tttttcaatt tctgatccta cttcattgtt cgtcggtgaa tccaatggca
     9541 cagaaggatc cattacagca aattcttcat tttctttgat caattgatta gagaattctt
     9601 tttcagggtc tgtatctttg aaagagaacg tcacttcact aggacgagag cttgataacg
     9661 gttgcacctc ttgttgccaa agatccatat cgataaattc gatagaacca tcatcattca
     9721 attcataatg cgttccttcg ataccgccag tcatcaattt atacacatct tcttctaaaa
     9781 gatcatcaac aaattgaagt aatttcttca attgtgcttc gtcttttact tgagatttgg
     9841 gaaatgctag caagccgcca ataccatttc cttctgacca aacatgataa ccgccgcctt
     9901 caccatctga gatcttgttt acaggcacta attccatatc atcttgaata ccttgaccca
     9961 tcgtcttcag attcttgata tccaccattc cagtgtagat tccagttctt ccttgtgcaa
    10021 attgttcttg ctgatcagtc ttttgggtaa ctgcaaagtc ttgtgccaaa tagccattct
    10081 caaatagatc tcttgaaaaa ttcaaagctt tcatatactc ttctgtatca aattctggag
    10141 tgaatttgcc attatcgtct acagcccagc catttggtgc tccaaaataa gaagtgaaaa
    10201 gtttaaagct ggtataacga atatcactag gcgcacgatc gccaaaacca actgtgtcgt
    10261 ccacaccatt tccatcagga tcgttttctg taaattgttt agctacttca taaagctcat
    10321 ccatggtagt tggaacatct agtcctagat tatccaacca gtcttttcga atgactaagc
    10381 cagcacgagc gtagtctttt tgtatcggta cgccgtacaa ggcaccgtcg atactcgcag
    10441 cttcgattct atcttcagaa atttgactta aatttttata gtcttttaaa tattctgata
    10501 catcccagaa tacgcctgat tttaacgcat tgcggacaga agagtttttc aacatcgcaa
    10561 tttgaagtgt aacgatatct cctagttcat cagaagccaa tgcagttgtt aatctttctt
    10621 cttttgaagc atcaggaatc cagttgaatg tcagttccgt atcggttttt tcttcgatca
    10681 agttcacaat cgtgtctgta ggcggtgaag catgatgcaa aatatttaac caagtgattt
    10741 tagcttttcc atcttctgtc tctgaagaac tgttacttga actgctgccg catgcggcaa
    10801 gtgctagaat tcctgcaaaa ctaagaccta attttacgag cgttgctttt ttcataaatt
    10861 ttctccttca ctgttttaat aatatttttg ttttcttctg ttttttctgt atatgagttc
    10921 ttccattcca aatggcaaaa tatagaattt gctgtccacg tgactgcgga aaagaagaga
    10981 ctgccaccga taaaggttaa aacacctggc attgtttgga tgatcatcag ataaatccct
    11041 accatactta atatcaacac taatgagtaa tgaagatgtg agaatccgaa taaaaatgcc
    11101 attttcattt tgaaaaaata tcctttccaa tcataatgag ccatgattgg gaaaatatag
    11161 agtgctgaga gcacatatat gaacgcagca atatacaaag cgatcctaag ataccaattg
    11221 tgtatgaaag aaagatccac aagtaaaaca atcccgatgg cgccatatat ccagctcatc
    11281 agcaaggttt cacgatagtt ttctttaaaa tatgtgaagt acgttttcgt caaaggaaac
    11341 gtttcttttg agcgcagcca ttttctaatc actgcaacca tcgcatacga tgcaggaccg
    11401 aaagtaaaaa ctcccaaacc tgcgatgact aaaccgcccc acagaaaatt caaataaacc
    11461 aactgtaaaa tacgatttag ccttccgttt attttatcta atgactgcag catatctttc
    11521 cctctctttc tatcttagta aacgccgtct tctcctagct ttttggcaat cttattagct
    11581 aaaattacca taaacaatcc tacgacccct ttaaacaatc ccattgctgt actgaaactt
    11641 aactgtccat tcttcaatcc agctgtataa atataggtgt cgaaaatttc tgcaacgctt
    11701 cgattcaatg aattcaataa caagtacata tgctcgaacc ctaagtctaa tgtctgaccg
    11761 atttttagaa tcagcaaggt aatgattact ggacgaattg ccggcaatgt aacatgccat
    11821 gttttgcgta agcgtcctgc tccatccatt tctgcagctt catacaactg tgtatcgact
    11881 gcagttatcg ctgaaaggta gatgatcgta gaccagccca actctttcca gatcacttgt
    11941 ccgatatata ctgtgcgtgt ccattcaggg gatgttagaa aactgatttt ttcaaatccc
    12001 attgttgcaa ggaattcatt caatacccct ccgtcaacat tcaaaaatac ataagtaatc
    12061 gaaacaatga ttacccaaga catgaagtga gggatgtaaa tgatcgtttg aatcccgttt
    12121 ttcaatcgtt tgttcgttac ttcatttaat agtaaagaca aaatgattgg catcggaaaa
    12181 aacacgaaga tatttaatcc gaacaagatc aacgtatttc ttaataatgt aaagaatgtc
    12241 ggttctgtaa acaaacgaat gaaatgtttg aaaccgaccc aaggacttcc cattattcct
    12301 aaaaatggtt gataatcttg aaaagcaata acgagtcccc ccataggaag atacctaaaa
    12361 atcaagaaat aaaggactcc cggcagaatc atcacatata aaaatttatt cgttttgatt
    12421 cctgcaatta ttttttttcg tcttctgagc ttttcttctt ttttcgatag cgtcagttga
    12481 aatggttctt gtttctttac actttccata agcccctcct tagttttgtg aatgtttgct
    12541 gcttatgact tcatgataga taactatctg aattacgtat ataatcattt ttatcgtaag
    12601 taaaaacgct tacatagcaa tgatttttgt gctatacaaa acgataaagt gtattttttc
    12661 acaaataaac tacgcatagc aaaccttcta tttttttcta tctgacactt agcataggaa
    12721 atgattatat acgtaatctt tcaccgatga taaattgaac atatagaaac agaaacattt
    12781 aatttatttt gaggaggagc ctatctatat gaaaaagaaa gtctctatag gagaaagaag
    12841 ttttacactt ttcaacaata cgtttctaat tttgctagct ttgatctgta tcgttccttt
    12901 tttaaatatc atcgctacat cttttgcttc tacacaagaa gtcgtcgcga aaaagtttat
    12961 cctttttcct actacctttt ctttagacgc gtatcgctac attctttcta cgccgaccat
    13021 ttttagagca cttgctgttt cgattggtgt tacaggtgtc ggaacgatcg tcagtatgtg
    13081 tgcaacttca ctgatggcct acggtctttc cagaaagtat ttgtttggtc gaggtttcgt
    13141 caactttctt gttgtatttt ctatgttgtt cagcgggggg atgattccaa cgttcttagt
    13201 tgttcgttct ctagggctgg tcaattctta ctgggccatg atcctgcctg tggctgttaa
    13261 tgcaatgaat atgatcatta tgagaaactt tttccaagcc ttgccggata gtttggaaga
    13321 atcagcaaaa atggatggtt gcacagattt tggtgtattt ttcaaaatta tgctgccatt
    13381 agctttaccg tctattgcta ctatctcgct tttttatgct gttacttact ggaacactta
    13441 tatgactgct attttgtata tcaacgattc atctaaatgg ccgatacaga ttcttttacg
    13501 ccaaatcgtc attgtatcaa gtgggatgca agcagaaagt agtgccgttg atgtgattcc
    13561 accagcacaa acagttaaaa tggctgttat cgttattgca acagtgccta tgctgattgt
    13621 ttatcctttt gttcagaaat attttgtcaa aggagcactc gtaggttctg tcaaagggtg
    13681 attatgtact gaacgcaaaa tggtagttgt gtcagaagtg gtcagcttca agaaataaga
    13741 aggcatttac gaaaattgct tcttaaattt ttgtgaaatt tcggcttatt tttcgaagaa
    13801 tctactcctg gaacaccgtg tatcagaggt tgtgaaagag acgttcagcc ttgagcgatg
    13861 ataaaaactc tcacaaacat tgcgacgagt aacccacagg agcaataaga agcgattttg
    13921 aaaaatagct tcccatattt cacaaaatta tgccttattg tcgatagcct gtctcttgaa
    13981 cgccatttat tcgtaaaaaa gaactgtgac aagacttttg tcacagttct ttttgcgtgc
    14041 ttagccttga aatttaacta tccataaata caaatactag ggttattcta acttctttta
    14101 ttgcttgaat cagtccacaa gaaaaacagc ctcttgatta aacggcgttt atcttgttga
    14161 ttctgcggca ataaaatcag ccagcagcaa aacatgaagt gctgtttttt gctgtcctct
    14221 tttattgctt gaatcagatc acaagaaaaa cagcctcttg attcacaaat atttttttcg
    14281 atattctccc ggcgtaatcg attccttctt tttaaagaaa cgaataaaat tttgcggatt
    14341 tcgatattgc aatctttctg caatctcttt tacggagagg ttagtctctt tcaaccattt
    14401 ttttgctacc tctaaacgat gattttgaac aaaatcacca aatttttctc ctgtttcctt
    14461 tttaaataca ttacttaaat agttagggtt ataatgcaac ctatcagcga tcacatctaa
    14521 agacagatca cgatcatatt ctgtgtagac gatatgcata atattctccg acaaattttt
    14581 aaattcatga tcagtgattg cttgagagca ttctgtgatt ggcagaacta attgttctaa
    14641 aacaagtttt tctagttctt tgggatgata attgttcagt gcttttacat aaatttgttt
    14701 catgttatca aagttttttg aatctactcc caataactgt cctaattgaa cgagttcatt
    14761 gatcaagcgg accgaaacta cttcccgact caaaggattt ttattttgtg caaacaatgc
    14821 atcaatcaat tcatgtacta aattcttcac ttcctgattt ccagaacgaa tggcttcaaa
    14881 caatcgattt tgttcttcta tcggatatct aataagtgtt ttttcatgag cagcaggaac
    14941 gatttcctga taaaaaataa ttgaacttgg accagtattt acacgataat acagggcttc
    15001 ttttgcccga tcaaccgatt gcttgctttc attcagcgtt tcgaaccggt tactgatgcc
    15061 tatactgata gttaaattca agtattcttt tacacgtttt tgaatgagtc ggcaatactc
    15121 catgactttt ttgcttgctt ctgcatcatc tttatccatt cgataaatag tggcttgcat
    15181 ttcttcattc aaaacgatcg gcagcattcg attttccttt ggcacaattt ccgtgatcat
    15241 gttgttgatc gctaaaagta gcaaatcacg ctccccaccg tgactatctt ctaacagatc
    15301 gatttgaacc aaagctgtat aatagcagtc attttgagaa ctataaccaa attgctgcaa
    15361 ccgctgatct agttctcgcc tttctactcg atttctaaat aaactaagta caaatagcgt
    15421 ttccagctgt ggcttttggg taactaagtg tgcacttaac gcttcttttt ctcctatgat
    15481 ccgactgact gattgagcga ccaaatctag ttctttccca ctgaatcctt ttgatttaag
    15541 attcagacgt tcctgtattt gagaaatcgg acgggcaaat ctgtccgaaa ataagtagga
    15601 aaaaagacca atgagtccta ccagtgttaa agacactgca actagcccga ttctcagatt
    15661 gcggatcatt gcgccaattg cactagagtc aacttctaat ctgtaaatcc aattattata
    15721 atctgatttc agtactatat acgttttatc tttttctctt atcactttca gctgattgta
    15781 atctagatcc acgtccgtta atacagttgg ttgctcttta ttttttactg tctgagtagt
    15841 aaaaaggttg ccaacttcgt tttcaataga aagtatgtct tctccacttt caccaacaac
    15901 ttgttctatt gtatgtttct ctatcgtagc aattcccaat gcatattttt ctttttcaaa
    15961 cattggcaaa gaaatcacca tttcgattcc tttgtttttc ttttgccaaa ataaattatt
    16021 tttgttattt atgtacttct gttgatactt ttcaacttcc tcttcggtca gttgactcaa
    16081 cgatccattg attactcccc atttaccagc caaactgact aaatcataat tattatcatc
    16141 cataacaatc gtttctataa aatttagttc tttcctgatt tcagaataag tggagtaatc
    16201 tgtatatgtc agcggatgct tgaatatgtc cgagaaattt ttggtcgaac catacgtaga
    16261 aaacgaatat tcaatcgttc taattttcca ttcaacgtta gttttaactt gcctgagcaa
    16321 attctttttg tctgttaaat aactcgattc gatcgattca taggtattct ggtaaatgaa
    16381 taaactaaat cctatgacaa gtacggctcc taataaaaac atcggtaaaa atattttata
    16441 aaatactgta cttttcttca ttttcttcct ctcctccttt taaaataaaa ggctttcatt
    16501 tttctgtaaa attgatactc atctaattaa atgagcattc cccgctttca agaatagcat
    16561 aattaaaaat aaaaatccaa gtaattttta acgtgtgcaa tcttttcata tcaaagatct
    16621 attgacttat cgtagttatc gtaatatgat gaatgcgtta acaaaaagtg aaaaagtaag
    16681 gaaaatgatg gaatggtaac gatcaaagat atcgctaaag cagctggcgt ttctcatacg
    16741 acagtttctc gtgctttgaa taacagcagt ttaataaaaa atgaaacaaa acaaaaaata
    16801 cgacaactag ctaaggaaat gaattattcg ccaaactata gtgcaaaagg tttagtgaat
    16861 caaaaaaaat atctaatcgg actatttttc tcaagtttgc ataaaggaac ttcatcaaat
    16921 ttcctagcag attccattgc aggcatccat tcagtattag acacaaatta cagtttatct
    16981 gttgaaagta tcgatgttgt tgatttaaca gaaatcaacc tgcaacgcta cgatggactg
    17041 atcgttatga gtcaaagtga tgatgatcag cctttcatcg actatctcaa agaaaaagaa
    17101 tttcctttcg ttgttgtcaa tcgtcacatc aatgatccag cggttatcaa cgtcactgcc
    17161 gatgatgcgg ccggtgttat gcaggcagta gattacggta ttggatgcgg acatacgaag
    17221 atcgcttata ttggcggaaa gaaaaatttt cgttcgacaa aagaacggga aaaaggggta
    17281 ttgaaaagtc taaaaaaagc gagcatccct gtcaatctag cctatttttt aacaggagat
    17341 tacagcttag aaagcggcct ccaaaacatg gaatacctat tatcactttc tgacctgcct
    17401 actctggttt tttgcggcaa cgacgacata gcgattggtg cattgagagc tgtacattta
    17461 gctggcctcc gtgttcccca gaacatttct ctgatcgggt tcgatgattc tccagtcgtc
    17521 tcctatctca atccgccgct taccaccgta cgtaagcctt tgaaagaaat gtgtcaagaa
    17581 ggaacaaagc ttttactaga tttgatcgaa ggcaggacga tcgaacaatc taaaattgag
    17641 ctctccacct tgttgatcct tcgtgagtcg atcaattact tgtaaactac aagtaatttt
    17701 atataaaaat gttaacgtgt gcataacaca gaaaggaagt ttatatgaaa aaactgacaa
    17761 aagaattagt gaaaaaaaac gaagcacctg taaaagttct tcagtttggt gaaggcaatt
    17821 ttatgcgtgg atttattgat tggcagattc agcagctgaa taaccaacaa ttgtttaaag
    17881 gtaatgttgc aatcattcaa cctttagaac aaggtcttgg aaatatgatg aaccagcaag
    17941 ataatttata tacggtcatt ttacaaggac tcagcaatgg cgaaatcgtt gatacttccg
    18001 agattatcac cgtagtagaa caaatgatca atccttatga tgaatgggat gcttatctat
    18061 ctctagcaga aaatgacgac ttggcctata tcgtctccaa tacaacagag gcaggaatcc
    18121 aattcgtgga gactgataat ttaacagata ctcccccaca gagcttcccg ggcaaactga
    18181 cagccttttt ataccgacgt ttcaaattaa acaaagctgg ctttaccatc attccttgcg
    18241 aactgattga cagaaacggc gaacgtctaa aagaaatcat tttacgctac gcagaaaaat
    18301 gggatttaga acctgctttt gttgagtggt tagaaaaaga aaatgttttc tgttgtagtt
    18361 tagttgatcg catcgtccca ggttatcctc gcgaagatgc aggtgttttc aatcaacggc
    18421 ataactatga agatcaattg atggtcaaag cagaaccatt catgctttgg gtgatcgaag
    18481 ggcctaaaga attggagaat caactaccat tcaaacaggc tggcttgaat gtcatcatca
    18541 cagatgatat gactccttat cgtgaacgta aggtgcattt gcttaatgga ccgcatacag
    18601 cgatggtccc tcttgctttg ttggcggaat tggaaactgt agaagaagta atgaaagatc
    18661 ctttattctc cgcatatgtt gatcagttat tcaatctaga attgattcct atgctttctt
    18721 tacctaaaga tgaattagcc atttatgctg accaaatcaa agaacgtttc ttgaatcctt
    18781 ttgcccatca caaattagaa gcgatttcat taaatagtgt ttcaaagttc agcacccgtc
    18841 tgcttccagt gttcaagaag tatatcgaag aacaaaatca ggtaccaccg ttaatcactg
    18901 tttcactagc tgcgctactt cttatgtatc gaggcgatca agtaaagcca catgatgatg
    18961 aaaagacgat aagcgaattt actgatgctt ggtctgataa tggaacagct attcctcgat
    19021 tattgcaaaa cgctgcgctt tggggagaag atttgtctca aataccgaat gtgacagata
    19081 cagttcaaga aatagctgca aagatcgatc aaaaaggtgt ccggtcagta ttacaagaaa
    19141 tgaaaggaac gatggtccat gcttgaaacc ctgcaaccaa caatgaaatt aaatcgacga
    19201 gacagtgtgg tcgtcgcatt aacccctatt ccaaaacaaa cacaactgac gattgatcag
    19261 caaacgatca ccactcttga agatatcccg caaggtcata agattgcatt gggtgatttg
    19321 aaagctggag acaacgtgat caaatatggc tatccaatcg gtcatgtgac gacagacgta
    19381 actgccggtc aatggctgca cactcataat gtaaaaacca atctttctgg tgaattggat
    19441 tatcgatatg aaaaagatgt ccatccaagt cattaccttt ttgagaaccg aacatttcaa
    19501 ggttacttgc gaaaaaatgg aaaagtaggg attcgtaatg atttgttttt agtacctacc
    19561 gttgggtgtg tgaatggcat tgctgaactg atcgtcaaac agttcaagga aaaacatcca
    19621 gatctgggac agtttgacca tattacgatt ttaaagcatc cttatggctg ttcgcagctt
    19681 ggaaaagatc atcaaaatac tcgagaaatt ttagcggacg cagtaaatca tcccaatgcc
    19741 ggaggagttt tagtatttgg attaggttgt gagaacaata cagttcctga attcaaaaaa
    19801 attttaggtg aatatgatga agaacgagtg aaatttctag tggctcaaga tgtttacgat
    19861 gagatcgaac aaggtgtggc tctattagaa gagcttttaa cagcggcgga aaatgaccag
    19921 cgcatatcag tcccgctctc taagttgaat gtcggtttga aatgcggcgg ttctgatggt
    19981 ctatcgggaa taactgctaa tcctttactt ggtgcatttt ctgactactt gattgctcaa
    20041 ggaggcagca cgatcttaac agaagtgcca gaaatgtttg gcgcagaaca agtattgatg
    20101 gcacgagcgg aaaatgaaga agtttttgac tcaatcgttg acttgatcaa tgacttcaaa
    20161 cagtatttct tgtcttacgg ggaaccagtt tacgaaaacc catctcctgg taataaagca
    20221 ggtgggatca ctacattaga agataagtct ttaggctgca cgcaaaaatc aggaagctct
    20281 cctgtcgttg atgtgctaca atatggcgaa aaaatcagaa aaccagggct tagtttattg
    20341 caagctcccg ggaatgatct tgtagctgcc tctgctcttg cttcatccga ttgccagttg
    20401 gtcttgttta ccacaggaag agggactccg tttggctcat atgtcccaac ggtcaaggta
    20461 tctacgaata caactctttt tgaacgcaaa ggtcattgga tggattttaa tgcaggcgtc
    20521 ttattagaac aaccaatgga agtaatctta gaatcgtttg ttcaaaaaat catcgctgta
    20581 gctagtggag aagaaacgaa aaatgaacaa aatgacgttc gagaaattgc catttttaaa
    20641 aacggagtaa cactttgatt ttcataaaac agtataaaaa gaaagaagga agatttatgt
    20701 ttttatctga tgatttttta ttaaaagacg attgggcgaa aaagctttac cattcctacg
    20761 caaaaaacat gcccattatt gattatcact gtcacttaga tccaaaagaa atttacgaaa
    20821 acaacaattt cagcaatctg acagaagctt ggttaggagg cgatcattac aaatggcgct
    20881 tgatgcgagc ttgcggcgtg cctgaagaaa aaatcacagg aaatgcttct gattttgaaa
    20941 aatttttagc ttggtgtcaa accgtaccaa aaattatcgg aaatccgctt tacagttggt
    21001 cacatcttga attgaagcgt ttcttcggta ttgacttgtt gataaatgaa gaaaatgcag
    21061 agaaaatttg gacacaagca aatgaaattt tggcagctcc tgattttcgc cgtcgggaaa
    21121 tcgcaaaaaa atcgaatgta gaagtgattt gtacaacaga tgatcccgca gacgacttgc
    21181 actatcatca gttgcttgct catgaagaac cagatttgaa ggttctacct tcattccgtc
    21241 cagataaagc actcaatatt gaaaaagaag gatttaatgc atgggtcaca ctactggaag
    21301 aagcagctga ccaaacgatc accacctatc aagaactgat agaagtctta gggcagcgga
    21361 tagaatactt ccatcaacat ggatgtcgtg tttccgacca cgctttagac atcttacgct
    21421 ataaagaagc ggatgaaaca gtattagaag agatttttca aaaagcacga gctaacaaac
    21481 tattatcttc agatgaaatc gatgcttatc ttacagaaac actgatacat ttgacccact
    21541 tctatcattc tcataattgg acgatgcagc tgcacatcca tgcttatcgt aactgtaata
    21601 cacaaatgtt ggaaaaatta gggcccgata ccggctatga tggaatgaat gatctttctt
    21661 tgactattcc tctgcaaaaa ttattgaacc gtgcagaaga aacggatcag ttgccaaaga
    21721 cgatccttta ttcattgaat ccgaatgact atcctgcgat tttagctttg atgggctgtt
    21781 tccaaaaaga acagaatgga aaactgcagt taggttctgg atggtggtac aacgatactc
    21841 gagctggtat gcgcgatcaa ttgacacaat ttgctgatgg tagtgctttg gggaattttg
    21901 tcggcatgct gacagattca agaagtttcc tgtcctacac tagacatgaa tatttccgtc
    21961 gtgttctttg tgaattttta ggcgaaatgg tcatgcgagg agaagcacct gaagatgaac
    22021 aacttttagg aagtctagtt caagcgatta gttatacaaa tgctaaaaat tactttggct
    22081 tttttgccta attgattaat agtaacagta acgaatcaaa aacaggatag tgaaataacg
    22141 gaatccgttt atccacgttt tagagaagaa gacggaccaa
//
LOCUS       DARBDN010000037        22031 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000037 DARBDN010000000
VERSION     DARBDN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.037"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            367..555
                     /locus_tag="SCH06_001407"
     CDS             367..555
                     /locus_tag="SCH06_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077992.1"
                     /translation="MELIVFTNNGQTYHFYEVENFKPTTTGFSFIYTGKATGVTRSAT
                     FNNTSTAGYALAEVQNES"
     gene            545..805
                     /locus_tag="SCH06_001408"
     CDS             545..805
                     /locus_tag="SCH06_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077993.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSIFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            846..1073
                     /locus_tag="SCH06_001409"
     CDS             846..1073
                     /locus_tag="SCH06_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077994.1"
                     /translation="MRNYWYVSLTNEYPRTIGDCSVRVVRSVQIKGKYSIVEMLREAT
                     PNEVDKCKLIYCGHGYWKDEYIQYNIERYIK"
     gene            1138..1710
                     /locus_tag="SCH06_001410"
     CDS             1138..1710
                     /locus_tag="SCH06_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077995.1"
                     /translation="MKLKDYIREGYNVVTAPNLAYKIQEDYPNALVFTDRALDAIPIG
                     KLLVDRFYSNNPAVLSAKPLQNAYAIERFTCEFTGYETVVPMTGETGRKVIQQIKKRI
                     AELTLDDGSNTNLLEIKLRDTDSVPEVYYKGQRMDEMPIGLVDITYHWDTEEYECQVP
                     KGANDITIEYYDSHNNKYLDRKIIGHKRDM"
     gene            1711..2022
                     /locus_tag="SCH06_001411"
     CDS             1711..2022
                     /locus_tag="SCH06_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEG1077996.1"
                     /translation="MIDVSSKQARARFYGSTEWRKLRSQCLERDHYECQWCKAEGRLT
                     TQHDSILEVDHIKELEYHPDLALDINNLRTLCKDCHNKRHNRMKYRGQQKKRKWDDEW
                     W"
     gene            2013..2273
                     /locus_tag="SCH06_001412"
     CDS             2013..2273
                     /locus_tag="SCH06_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077997.1"
                     /translation="MVVRKTANRDDVKRAEAIAMVDKAIDKLVLFKSQLIEGTTTVED
                     ISINNRLIGNANEVTGTFNINVDIDYTLSPFAHIVESNEQDG"
     gene            2434..2793
                     /locus_tag="SCH06_001413"
     CDS             2434..2793
                     /locus_tag="SCH06_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1077998.1"
                     /translation="MADLQERNRLVSAEERRLNKLFKDIDKDKKKVVSGLITQAARLK
                     ILLDEMWIDISEKGDYELFSQSENQKPYERERPVAKQYNSRDQAYQRVIKQLTDYLPE
                     EKREPTKNAALDGSDLL"
     gene            2790..4433
                     /locus_tag="SCH06_001414"
     CDS             2790..4433
                     /locus_tag="SCH06_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEG1077999.1"
                     /translation="MTTLKPFYFDEYVDLYEKGVIPFNKERIQLITYLKNEVLVRDDI
                     YFDEEMIQKFIKYTEKNFFPLAKYQKFITPFIFCYQKEDDEVFFDEILNSIARGGGKN
                     GFMSARDSFFISPLYGVRNYDVTITANSEKQGKVSFKEVYEMVQMRKLEKQFYLTKMA
                     IVNNVTNSIFSYRTNNPKTMDSARDGCLEFDEIHQFESSDLVDIQRSGLGKIKHPRTF
                     YNGTNGHVREGFYDKMLERAQKIFSGENKNDRLFPFICKLDNIDEMDNPKMWSKANPM
                     FEEDSAYSKRLFSTVMKEYKKLEDEPSGRREFVVKRMNFTEGDAESDITTHEKLMATK
                     QELPNLNGRSCVAGFDYASIRDFATVGLLFKIDDKFIWQQHSFARKKFLDTFKLKAPI
                     KDWEKKGLVTIVDEPSIDPRHLIDWLNEKRKIHQIEIVCADGFRMDLLKPLLEKESYN
                     FEFIRNIRGVQSKVAPIIEDGFANERFIFGDDPMMRWYTNNSFIKEDKLGNKTFLKKE
                     PVRRKTDGFHAFLAALYKREEITDMDYEEAFDMLDEIEF"
     gene            4468..5550
                     /locus_tag="SCH06_001415"
     CDS             4468..5550
                     /locus_tag="SCH06_001415"
                     /inference="COORDINATES: protein motif:HMM:NF028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078000.1"
                     /translation="MKKRYFLFVTIFIIIAICVLTVFLPQITEYLNYRIFTTKVDDSV
                     TSLSRLEFIKICASVFGPILTVMVFVNTLNMQKKTEQKQNELEVKQAKAENERAKKEL
                     LTQIDREFYFLLNMFIEIQKDQNAKQAVIALQKLAIFNEKGFNQDYAFTSKDLSDSEI
                     GSTIEQSGPLKGTVEYIKFETFDVSKSMGNYQTKTKDVATSLHDQKVAILNEQYEKMQ
                     IYLGRYFKMFHRIVKTLNEYYDDYNDFDVKRYTKYIGTLRTQISPAEFQVILFNSLYI
                     KRGFGLGIQLIGSGFFGDDFDFETNQHFETSINEQWFLSLSTVDSDNSIKRQKLSEYI
                     KELGSVEYKKIANFESLYKLFNETKL"
     gene            5594..6766
                     /locus_tag="SCH06_001416"
     CDS             5594..6766
                     /locus_tag="SCH06_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEG1078001.1"
                     /translation="MSLFDIFKQSIRNEEPSEWIPDFVYGEEVSARAYLKIMAKNTVL
                     DFVARTMSTLEVKFKNKDGTSDWDYILNVRPNSDMSAATFWQKFFYRLLDDNEVLVIF
                     TDDNQLLIADDFSRTEYAVYDDVFTNVMVKNFVFERSWNMSDVIYMEYNNEELERFTR
                     GLFEDYAALFGRILEVAMRNNQIRGSVSIDSTGTANDEKGKDGKTRSQRLQEYIDRIW
                     NSFKTNSVAIVPKVKGFEYEEYTNKQGVSNQSLDELNKMKSSLIDDVANAIGVPTALI
                     YGEKAELDSNIKAFRKLCIAPLVKKLQDELVAKIISRQEYKNGERIEVKKVLQKDLLE
                     YATQIDKITSGGAFYIDEVRDEVDYDELPNNEGKIRIRTKNYEETVKGGENDNAES"
     gene            6753..7457
                     /locus_tag="SCH06_001417"
     CDS             6753..7457
                     /locus_tag="SCH06_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEG1078002.1"
                     /translation="MPKAKKVPFQFTNEIQNGKHILTLSGNVQKKYWRDDDVINAKDI
                     RDSLDTVTDDIVIKLNSPGGDVFEGIEIYNYLKDHPSNITVEVTGLAASAATFIVAGA
                     NDVIMNVGTSLMIHEASTFAWGNKQDIQKTLNALETIDDSILAIYSDKTGQSVDKLRE
                     WMNEEKWFTADEAVKYGFANSVKREEPQNEPQNIAAMIQDAVAVAIANLKEPVTNKIE
                     QESKQKSLIARLRKGE"
     gene            7462..8622
                     /locus_tag="SCH06_001418"
     CDS             7462..8622
                     /locus_tag="SCH06_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEG1078003.1"
                     /translation="MLKITDKTADAKKAFNAISSKEDATPEQINAALEEYVTAIAEDA
                     GKQVRAEYEELKNVTDNRVLEARGIPTLTAEETKFYNEAVKSGGFDSDVVWPETILER
                     VFENLQNDHPILGLINFTPTVGRVKVIRARRKGVAVFGPLHKDLEGQLDAEFGATEFV
                     QLALTAFFLISNDTLDLGPRWIDRFINLSLSEAVRDVWAKKIITGSGKDEPIGLLKDL
                     DGAVTSGVYPDKASAGTLTFAKEKIVLELAGVMKKLSKYTYKVDGDDEGEVKYRSVAG
                     RVYLIVNPVDYWDIVARVTFANLNNVYGTTMPFIAVDHIIESVDVPESKCIAYVDKEY
                     EATQSRAEKVYVYKETFAMKRATLYAVDMLGNGYPTNNDAAQVYDLDFTAGE"
     gene            8698..8976
                     /locus_tag="SCH06_001419"
     CDS             8698..8976
                     /locus_tag="SCH06_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEG1078004.1"
                     /translation="MNTEEFIKEYKARFRIFHTSEDEDIGKQLESGFADIKSLIGSFD
                     PSTYEKGKELVYERTRYLRNESLEYFYDNFQTMIMDASIDLAGAGYAN"
     gene            8957..9328
                     /locus_tag="SCH06_001420"
     CDS             8957..9328
                     /locus_tag="SCH06_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEG1078005.1"
                     /translation="MLDMPIKSNYKKPKIVAGDLNTPVTFFEFQPNKGPEPGDEEKKE
                     LYFCTALVYNPSMKDRDILGTKEGVTIKIRDPHQSYIPTNKHKVRILDYRYGDKVWEI
                     IDVSPDLEENSIVKIVLELIT"
     gene            9344..9748
                     /locus_tag="SCH06_001421"
     CDS             9344..9748
                     /locus_tag="SCH06_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078006.1"
                     /translation="MSNVKFEGVQETIQALEKKYGEKKTKTLTKKAINVGAEKVEKQL
                     QTDMTVFKDKGYTIAEVVRKNATYRDYKAEAEIGWNGPHQRYRIIHLNEWGYTRKGKQ
                     IRPRGFGVITKSLKNSELLYFDAVGEEVKKSL"
     gene            9745..10155
                     /locus_tag="SCH06_001422"
     CDS             9745..10155
                     /locus_tag="SCH06_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078007.1"
                     /translation="MKDMLNIIYEALCLNEYIHSMTYNENTEQYRIKFYEQPETADKT
                     GPMITIRPVDTPNEAYHGSNKELSVEHMIQIDVESKYRATCKQIQYEIKKEMKKLGFG
                     QISGQGLDEYFTETNRFVDARRYEGNTKIYDTEY"
     gene            10216..10803
                     /locus_tag="SCH06_001423"
     CDS             10216..10803
                     /locus_tag="SCH06_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEG1078008.1"
                     /translation="MTLVGFKKMTIGVFDSTGKIPAANLYVIEGEQNKGATVSAEISG
                     LSKEPSKVYGSNIAYYVSQKGTGDVSATFGLLDLPTEVNDKILGYKTDTNKISFLGED
                     TEPPYCAILMESEDLNGDTAMLAMFKGKFSRESINLNTTTNEAFEPEAEEYVFSAIAN
                     DVEGDAKGQTVAKYVGDEEASITGLKEMVFPAAGE"
     gene            10876..11343
                     /locus_tag="SCH06_001424"
     CDS             10876..11343
                     /locus_tag="SCH06_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HEG1078009.1"
                     /translation="MPDTFKIYKKNGTEFTKVAEGESPLSITGIAANTQVAKGDYQAT
                     RVVGGQESVKVDIPAFTTLPISVTGVTLDKTTAEVEQGGTLKLTPTVTPANATDKTGS
                     WSSSNTAVATVTGGNVTVKTDAEVGGTTEVSFTTTDGGKVAKCTITVIEKAAG"
     gene            11389..11697
                     /locus_tag="SCH06_001425"
     CDS             11389..11697
                     /locus_tag="SCH06_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078010.1"
                     /translation="MAKVRIELKEESGKKVYENIDTTGKDYRKALETIKKLNEDGVMI
                     WNRLDIYLDFAVGIFRDSKLTAEQILDGLPSEKVMSTLDDILGEVMGIESNPDPDAKK
                     "
     gene            11892..18626
                     /locus_tag="SCH06_001426"
     CDS             11892..18626
                     /locus_tag="SCH06_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEG1078011.1"
                     /translation="MANGKPLGNMIIKLDLDSSAFSKGLAGAKNAVNHQMKAMKSQMQ
                     VMNSSGNSLGALQAKYNGLGGVLQANEKQVELLTKAYKDSFDSNGNATASTAKYANQL
                     NQATARSASYESQMKTTVGQIARMKVETEGFTGKLKANSDVLINSGKKIEAFGKGVSG
                     IGSALTVGVTAPIVAGATAVTSAAISWESAFAGVKKTNDEVVDSNGNVVYSYSDLEKG
                     LRNLATQLPGSHQEIANVAEAAGQLGIKTENVVSFTKTMIDMGESTNMSAETAATSLA
                     RFANITQMSQKDFDKLGSVIVDLGNNFATTESEITEMGLRLAGAGKQIGMSQGEILGF
                     ATALSSVGVEAEAGGSAFSKVMIQMQLAVEKGFGAFDQLKQMAEEQGVPWVNLVNAVR
                     DGGKSLKAVSEQMGFTSSDLKKMYKEADNSKSSLENFANVAGVTSEQFQKLFKSDPSE
                     AIIKFIQGLKDSEKHGTSAIKVLDDMDIKEVRLRDSLLRAANASDIFKGAIEKGNGAW
                     KQNTALTNEANKRYETTESKLKILKNEVIDTAIDLGGPFVDALRDGLNVSKPLIKNLG
                     NMAKAFSAMSDDQQRNIIKWVGLAAAAGPALKLLGTGTSVIGKVTSTTGRLTKSLVDL
                     AAKAAEKKAMDAFASSVTTAGAAAAKTAGAGGIGGLVPMMGKTASAASTAAGASGIGA
                     MTTSLGLLGPALLGIVGVGGALAVGYGAWKLFGEEAWNSSQRVKQWGTDVGEEIDSTL
                     DGVQKNIEGANGQFGLLKEGFTVDDANNMAANFATAGTSLETSLTGRIKALDDALKGL
                     PQSVQDAMKEVAESEEETLGQSLSKIKDNNEEIKKIRERAANQNRDLTVSELQQIQDL
                     MKGTSQAYVDTLDVSAKDRKKILSAMNGDVAQATEEEAKTWLQSLAKQKAATTENYRQ
                     MLEEKKAALKEKGVSKEFIDALEDEMNDYIKTTNQGFDSQIAAITNKYPQLINEVSLS
                     NGQLFSKTAAAMDNTGQYTKVFLESNEKILAQAKKTSDEIADNAEKNAEQLGMVADEA
                     THAGSTWNGLVLDEKTGKVKTNVQEVVNEATKDFTKWNELKPVVHDAKLTTNAKDVIS
                     IAAVQNGYWDDMEWKEKEALLEDECSKNVYKALENAGKWNELDIPSKEAILTSNTPEV
                     MGETLMNLGLWDTYKLQVKDLDLNAYKVYDAIDGSEEKLNSWAQLDNPTKELLLDNSD
                     FSTKLFNSEEMFKRWNQLSSNAKFLSANNTKFTEVLLSSDRMWNQWVNLPDNEKRLLA
                     DNEDLATTVLSSEEIYGRWTQLPDNQKYMLADNTDLANKIFASEESWNAWKAIPDTVK
                     NLLGNNIDLLAKVKDGTVSVEEYNKVMPLLKTLYGDNVNLKEAISGAKSSIENYNKNI
                     FPSDKTAVGHDEASQAAKDAFEAFNIFQTKIPDKITKTVSADFIGPMPKNAKGTNFHP
                     GGAAMVNDQKGPTYEELITLPSGETFIPKGRNVVLDLPRGSKVLNATKTKRLVPKYAD
                     GIGNITTVSSTLNLDALILAINELTTVLRTQLMAGTTDAKDTKLSDETKVADPIIPDS
                     LSEKSDQYLGIGAQWLTNLMNGWNSAVPQYMNSEMVFITNYLNALKLQNNPNYTQGAT
                     WNKNLLNGWNSLTGTFIATINSFCNQAMVTLRNYNTPMYNNGRTWQQNNLNGWNSLYG
                     SFIARVNQLGNDSINNLRSKSGGFYNAGTFLLQSLINGMNSLGNSLSTTMNNVANTMV
                     GGIGKGVNGVISGVNYVLKEVESSKNIGNWPIPQYAKGTDGHPGGLAMINDQKGLVHE
                     EYVQMPDGRSFIAKGRDLLVNLPKGAQVLNASLTKKLKERLNIPHYEKGIGNLDIVDL
                     LDDEKRMLEFLTSKVDFSGINEPWLDMTKSGTSLMSKAANTMLQSKLSEFFTHGNFDG
                     AVNANGVYQYLVDVAQKVMGKFPGLTVTSGYRAGDAYYHGKRQAIDLAYPGISGDPRY
                     TAAANYAFEKFPSKIAYVITNGRVRDRMGLSGTRSSGQWTNWPDGDHFDHIHLNGSMG
                     SGDIFNGGVGGSGVARWRSYVSKALKMNGLPATAAYINAWMSQIQTESGGNEKAIGGN
                     DGLAEGNATGLLQTKPGTFAANAFPGHGNIMNGFDNMLAAINYAKKRYGVAGMLQVIG
                     KGHGYANGGLITKDGLYRAGEGNKPEMVIPLTRKTRAIELMGQALAFLSGSNKKETKS
                     EINSVDNRHILQAIEKQSRMTNDLLSLLLSFFKSNNRSDKELALDIQKILIRRT"
     gene            18630..19502
                     /locus_tag="SCH06_001427"
     CDS             18630..19502
                     /locus_tag="SCH06_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HEG1078012.1"
                     /translation="MRTVILRNKLNEEIDLSTEDYFATEMSNLGFEVTKEHIGQWGSF
                     REIGESIELSEFQSSVMISVHGFREQQLYGSLVEFLANGPFELEFSFDSETMIRKCSL
                     KSLSKTEIDSQSSLLTDTLNLYFTSSWYSIKREKLIQNSTSLNTRGKVYSFVRPYVYT
                     KNVWEKKGVFKFSNNSVYLTNSTERMSPLKIRIIGECSNPYWEVIQNSKVVASDGYFI
                     NMKDTQILEVSSLLEDQTAILKDVGGVESSVYQQQDFTKSNFVQAPLGEFSVVFHVGH
                     ANVEIELYEERDLF"
     gene            19499..20548
                     /locus_tag="SCH06_001428"
     CDS             19499..20548
                     /locus_tag="SCH06_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078013.1"
                     /translation="MILAITLFHRDMNLYNERLISTEFEFGTDEIGEEVSNFITDKYV
                     HVKSGDFLLAKFIPSGKIAYFGVISSQEDKKINCKGLLSLADSEIPTVKISGANYEEH
                     IRRLIEYYLLNDPTKQLKNILEVKTESVTSHSYQAVDTNKRRLNAYIINGFKKYNVKW
                     YVKEIKGKKIYTGIRAVDDSIYIKDNSSEFNDWDVFVQSPGPGNENKLLIVDKAMKDI
                     ENPLVLSTWYLDDENNLTQDSTNKNIALPTVNLVNIYDQTQEDRPSYEEVAKSELKGN
                     AYSHEIKVNVVLNARNINVENIETGMLATIVYKEQTYKSVLTAWRISSSKKNIELTFG
                     NVRSRFMDYFEDNGG"
     gene            20552..21376
                     /locus_tag="SCH06_001429"
     CDS             20552..21376
                     /locus_tag="SCH06_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078014.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVNSTGSTVSISKISDSYELTLS
                     KGEILWRGTALMHDTQTVQPSKKIWQTVSGFLLVWLPYENGQAIEDRYVTTPFYKERI
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            21394..>22031
                     /locus_tag="SCH06_001430"
     CDS             21394..>22031
                     /locus_tag="SCH06_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEG1078015.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKANNRIDQTNQQIGDLGKLKKMYSNSI"
BASE COUNT         7878 a         3297 c         4671 g         6185 t
ORIGIN      
        1 cttctaaatt gttcttatta tctatcatca gttgctgtct attgtcatta tgtcactgtg
       61 gtggaaaggt gtatcgctca tctaaaattt aggtgcaaac tgcaaggttc gattccttgc
      121 cagtgacttt ggtaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
      181 cgcgttttgt gcatcttgta ggttgctatt acataattgg ttgggttaga ttgagttttg
      241 ggattcggta caaatgaatc gtcaaatgac tcaagcacag gatcggaaac gtccctgcct
      301 gtgcattaca tattagatca ctctttgagt ggtcttttta ttttaaaaaa gagaggattt
      361 tgaaaaatgg aattgattgt atttactaat aacggacaaa catatcattt ttatgaagtg
      421 gagaatttta agccaacaac aacaggattt agttttattt atactgggaa ggctacggga
      481 gttactcgtt cagctacgtt taacaataca tcaacagctg gttatgcgct tgcggaggta
      541 caaaatgaat catgagaagt ttatcgaaaa atgcaaggct attgtacgtg aaagaattga
      601 aaatgagatt gctgacctaa gtggagcagt gcctgagttt agtattttca tagtctggtc
      661 atgcaaaaca ctgcaaaata gcaaagcatt agtcagcgct agcttaaaag gagcaccgta
      721 ttttgaaatt acgttgaacg gggacaaagg tgaaatctat gtagatactt atctcaaaaa
      781 atcaaatgaa tgtatcaaag tctagcaggt gctaggcttt ttctttacat aaaggaggct
      841 gcataatgag aaactactgg tatgtatcac taactaatga atatcctcga accattggtg
      901 attgttcagt gcgtgttgtg cgttctgtac aaatcaaagg gaagtactct attgtcgaaa
      961 tgctaagaga agctacacca aacgaagtgg ataaatgcaa gctgatatat tgcggtcatg
     1021 gctattggaa agacgagtat atccaataca acattgagag gtacatcaaa tgaatgataa
     1081 ctatgattac atcaagttgt tagcaagtaa ttattagatg tttttaggag gaaaactatg
     1141 aaattaaaag attatatcag agaagggtat aacgttgtaa ctgcacccaa tctagcttac
     1201 aaaattcaag aagattatcc caatgcttta gtgtttactg atagagcttt agatgccatt
     1261 cctataggga agttattagt agatcgtttt tatagcaata atccagctgt tcttagtgct
     1321 aagccacttc aaaacgctta tgctattgaa cgctttactt gcgagtttac tggatatgag
     1381 acggtagtac caatgacagg tgagacagga agaaaagtaa ttcaacagat caaaaagagg
     1441 attgctgaat tgacgttaga tgatggaagt aatacgaacc ttctagaaat caaactaaga
     1501 gatactgact cagtaccaga agtttattat aaaggtcaac gaatggatga gatgccgata
     1561 ggtcttgtcg atattactta tcattgggat acggaagaat atgaatgcca agtaccaaaa
     1621 ggagctaacg acatcactat tgaatattat gattcacata ataacaagta cttagataga
     1681 aaaatcattg ggcacaagag agatatgtaa atgattgatg tttcaagtaa acaagcaaga
     1741 gctaggttct atggatcaac tgagtggagg aaacttagaa gtcaatgctt agagcgagat
     1801 cattatgagt gccaatggtg taaagcagag ggtagactaa caactcaaca tgattcaatt
     1861 cttgaagtgg atcatataaa ggagctggag tatcatccgg atttagctct agatataaac
     1921 aacctaagaa ccttatgcaa agattgccat aacaaaaggc acaaccgtat gaaatatcgt
     1981 ggccaacaaa agaaaagaaa gtgggatgat gaatggtggt aagaaaaaca gcaaacagag
     2041 atgatgtcaa acgagcagaa gcaatcgcta tggttgataa ggctattgat aagttggttc
     2101 tatttaagag tcagctcatt gaaggaacaa caactgtaga ggatatatct atcaacaata
     2161 gactaatagg taacgctaat gaagtaacag ggacatttaa tattaatgta gacattgatt
     2221 ataccttgag tccatttgca catattgtag aaagcaacga gcaagacggc tgataaatca
     2281 gtataaagcg aagatatata gagtgaaata cccccggtca aaagattttg agaagaaata
     2341 aaatttttgg gaaccggtgg atggggtcaa ctctgcaaat aaatgatgct attttcacac
     2401 gaccccctcc ccacgtagaa aggaagtgag ttgatggctg atctgcaaga gagaaatagg
     2461 cttgtttctg ctgaagaaag gcgtctaaat aaattgttta aggatattga taaggataaa
     2521 aagaaggtcg tttctggttt gattacgcaa gcggcacgct taaaaattct tcttgatgaa
     2581 atgtggattg atatttccga aaaaggtgat tatgagcttt tctctcagtc agaaaatcaa
     2641 aaaccttacg agcgggaacg accagttgct aaacagtata attcgagaga ccaagcatat
     2701 caacgtgtaa ttaagcaact tactgactat ttgccagaag aaaagcgcga acctacaaaa
     2761 aatgcagcgc tagatggtag tgatttgctg tgacaacatt aaagccattc tattttgatg
     2821 aatacgtaga tttatacgaa aaaggggtaa tcccttttaa taaagaaaga attcagttaa
     2881 ttacttattt aaaaaacgaa gtgctagttc gggatgatat ctattttgat gaagaaatga
     2941 ttcaaaagtt tatcaagtac actgaaaaaa atttttttcc tttagctaaa tatcaaaaat
     3001 ttatcacacc tttcattttc tgctatcaaa aagaggacga cgaggtgttt tttgatgaaa
     3061 ttctaaatag tattgcgcga ggcggcggga aaaatgggtt catgtcagca agagactcat
     3121 tttttattag ccctctctac ggtgtcagaa attatgatgt aacgattaca gcgaattctg
     3181 agaagcaggg aaaggtatct tttaaagaag tttatgaaat ggtacaaatg cgcaaactgg
     3241 aaaaacaatt ttatttgact aagatggcta tagtcaacaa tgtaactaat tcgattttta
     3301 gttataggac aaacaatcct aagactatgg atagtgcaag agatggctgc ttagaatttg
     3361 atgaaatcca tcagtttgaa tcttcagacc tagttgatat tcagcgtagt gggctaggga
     3421 aaataaaaca tcctcgaact ttttataatg gtacaaatgg tcatgttaga gaaggttttt
     3481 atgacaaaat gttggaacga gcacaaaaga tttttagtgg agagaacaag aatgatcgct
     3541 tgtttccctt tatttgtaaa ctggataaca ttgatgaaat ggataatcct aaaatgtggt
     3601 caaaggctaa tccaatgttc gaagaagatt cagcatattc aaaacgtctg ttttctacag
     3661 tgatgaaaga atataaaaaa ctagaagatg agccatcagg taggcgtgaa tttgttgtta
     3721 aacgaatgaa ttttacagaa ggtgatgcag aatcagatat tacgactcat gaaaaattaa
     3781 tggctactaa acaagaattg ccaaatttga atggtcgttc ttgtgtggct ggatttgatt
     3841 atgcaagtat tcgtgatttt gcaacagtgg gtttgctttt taaaattgat gataaattta
     3901 tctggcagca acatagtttt gctaggaaaa agtttctaga tacattcaaa ctgaaagcgc
     3961 ctattaagga ttgggagaaa aaaggtttag tgacaatcgt tgatgagcca tcaattgatc
     4021 ctcgtcattt aattgattgg ttaaatgaaa aaagaaaaat ccatcaaata gaaatcgttt
     4081 gtgccgacgg atttcgtatg gatttgctga aacctcttct agagaaagaa tcatataatt
     4141 ttgagtttat cagaaatata agaggtgtgc agtcaaaagt tgctcctatt attgaagatg
     4201 gttttgcaaa tgaacggttt atttttggtg atgatcctat gatgcgttgg tatacaaata
     4261 attcgtttat caaagaagac aaattaggga ataaaacatt tttgaaaaaa gagccagtaa
     4321 ggcgtaaaac agatgggttt catgcttttt tggcagcttt atataaacga gaagaaataa
     4381 ctgatatgga ttatgaggaa gcatttgata tgttggatga gattgaattt taaggtatac
     4441 tccttattga aaggggtagt tatagaagtg aaaaagagat attttctatt tgttacaata
     4501 tttataataa tagcaatttg tgttttgaca gtatttttac cacaaattac tgagtattta
     4561 aattatcgga tatttaccac aaaagtagat gatagcgtta ctagtttaag taggctagaa
     4621 tttataaaaa tatgtgcatc tgtgtttggt cctattttga ctgtaatggt atttgtgaat
     4681 actttaaata tgcagaaaaa aacagagcaa aagcaaaatg agcttgaagt aaagcaagct
     4741 aaggctgaga acgagagagc aaaaaaagag ctgttaacac agatagatcg tgagttctat
     4801 tttttattaa atatgtttat tgaaatacaa aaagatcaaa atgccaaaca agctgttatt
     4861 gctttacaga agttggcaat ttttaacgaa aagggtttta atcaagacta tgcatttact
     4921 tctaaagatt tatcagatag tgaaattggg agtacaattg aacaatcagg accgctgaag
     4981 ggcacagttg aatatataaa atttgaaaca tttgatgtaa gcaagtcgat ggggaattat
     5041 caaacaaaaa caaaagacgt tgctacaagt ttacacgatc agaaagtagc tatattgaat
     5101 gaacaatatg aaaagatgca aatatatctt ggacggtact tcaaaatgtt tcaccgaata
     5161 gttaaaacat taaatgagta ttatgacgat tataatgatt ttgatgtgaa gaggtataca
     5221 aaatatatag ggacattaag aacacaaatt tctccagctg aattccaagt gattttattc
     5281 aattctctat atataaaacg aggttttggc ttaggaattc aacttattgg aagtggtttt
     5341 tttggagatg attttgattt tgaaactaat caacattttg aaacaagtat caatgaacag
     5401 tggtttctat cactatcaac tgttgacagt gataactcta taaagcgaca aaaattatct
     5461 gaatatatta aagaattagg atccgtagaa tataaaaaaa tagctaattt tgaaagttta
     5521 tataaactct ttaatgaaac taagctctag aaatagggct tttttatttt tctttgaaag
     5581 gtggtgaaaa catgtgagct tatttgatat ctttaagcag tcaataagaa atgaagagcc
     5641 ttctgagtgg ataccggatt ttgtatatgg agaggaagta tctgctcggg catacctcaa
     5701 aattatggca aaaaatactg ttttagattt tgttgcaaga actatgtcaa cgttagaagt
     5761 taagtttaaa aataaagatg ggacatcaga ctgggattat attctaaatg ttcgacctaa
     5821 ttctgatatg tcagcagcta cattttggca aaaatttttt tatcggctct tagatgacaa
     5881 cgaagtgtta gtaatattta cagatgataa tcaattgctg attgctgatg attttagtcg
     5941 aacggagtat gccgtgtatg atgatgtttt tacaaatgtg atggtaaaaa attttgtctt
     6001 tgaacgttca tggaacatgt ctgacgtcat ttatatggaa tataataacg aagaattaga
     6061 aaggtttaca cgaggtttat ttgaagatta cgccgcgttg ttcggacgga ttctagaagt
     6121 tgcaatgcgt aacaaccaaa ttcgtgggtc tgtatccatt gattcaacgg gaacggcgaa
     6181 tgatgaaaaa ggaaaagatg gtaagactag atctcaaaga ttacaagaat atattgatag
     6241 gatttggaac tcttttaaaa ctaactcagt tgcaattgtt cccaaagtga aaggctttga
     6301 gtatgaggaa tacaccaata aacaaggcgt atcgaatcaa tcgctagatg aactgaataa
     6361 gatgaagtcg tctttaattg atgatgttgc caacgccata ggagtaccta cggcgcttat
     6421 ttatggtgaa aaagctgaac tggattcaaa tattaaagct tttcgtaaat tgtgtattgc
     6481 tccactagtt aaaaaacttc aagacgaatt ggtggcaaaa ataattagtc gtcaagagta
     6541 caaaaacggg gaacgtatag aagttaaaaa agttctccaa aaagatctat tagagtatgc
     6601 tactcaaatt gataaaataa catctggtgg tgcgttttat attgacgaag ttcgtgatga
     6661 agttgattat gatgagttgc caaataatga aggaaaaatt cgtattcgta cgaaaaacta
     6721 tgaagaaact gtgaagggag gtgagaacga caatgccgaa agctaaaaaa gtaccatttc
     6781 agtttactaa cgaaattcag aatggtaagc acattctcac cttgagtgga aatgtacaga
     6841 aaaaatattg gcgtgatgat gatgtcataa acgctaaaga tattcgtgac tctctagata
     6901 ctgtaaccga tgatattgta atcaagttga acagcccagg cggtgatgtg tttgaaggga
     6961 ttgagattta caattattta aaagatcacc catcaaatat tactgtagaa gttacagggc
     7021 ttgccgcaag cgcagcaacg tttattgtcg ctggtgccaa tgatgtgatt atgaatgttg
     7081 ggacttcttt gatgattcat gaagcttcta catttgcttg ggggaataaa caggacatcc
     7141 aaaaaacgtt aaacgcattg gaaacgatcg atgattctat cttagctatt tattcagata
     7201 agactggcca atctgttgat aagttgcgtg aatggatgaa tgaagaaaaa tggtttacag
     7261 cagatgaagc tgtcaaatat ggatttgcca attctgtgaa gcgtgaagaa ccacaaaatg
     7321 aacctcaaaa tattgcagcg atgattcaag atgctgttgc cgttgcaata gcgaatttaa
     7381 aggaacctgt tactaataaa atcgaacaag aatcaaaaca aaaatcatta atcgcacgat
     7441 tgcgaaaagg agaataaaga tatgttaaaa attacagata aaactgcaga tgcaaaaaag
     7501 gcatttaatg ctatttcttc gaaagaagat gcaacacccg aacaaattaa tgctgctcta
     7561 gaagaatatg taaccgccat tgcagaagat gccggcaaac aggtgcgtgc tgaatatgaa
     7621 gaattgaaaa atgtgacgga caaccgtgta ttagaggctc gtggaattcc tacactaaca
     7681 gcagaagaaa caaagtttta taatgaagcc gtaaaatctg gaggtttcga ttctgacgta
     7741 gtttggccag aaacgatttt ggaacgtgtt tttgaaaatc ttcaaaacga tcatcctatt
     7801 ttaggcctca ttaactttac accaactgta ggtcgtgtca aagtaattag agcacgtcgt
     7861 aaaggtgttg ctgtttttgg accattgcat aaagaccttg aaggccaact agatgctgaa
     7921 tttggtgcaa ctgaatttgt tcaacttgcg ttgaccgcat ttttcttaat ttctaatgat
     7981 accttagatt taggaccacg atggattgac cgttttatca atctttcttt aagtgaagca
     8041 gtacgtgatg tttgggctaa aaaaattatt acaggttctg gtaaagatga gccaattgga
     8101 ttgcttaaag atctagatgg tgcggtcaca agtggtgtat atccagataa agctagcgca
     8161 gggacattaa cttttgcgaa agagaagatt gttcttgaac ttgcaggggt gatgaaaaaa
     8221 ttatctaaat acacatacaa agtagatggt gacgatgaag gtgaagtgaa ataccgttct
     8281 gttgctggac gagtgtatct aattgttaat cctgttgatt actgggatat cgtagctaga
     8341 gttacatttg caaatttaaa caatgtgtat gggactacga tgccatttat cgctgttgat
     8401 catatcatcg aatctgtaga cgtaccagaa agtaaatgta ttgcatacgt tgataaagag
     8461 tatgaagcta ctcaatcaag agctgaaaaa gtctatgtat ataaagaaac ttttgcaatg
     8521 aaacgcgcaa ctttgtatgc tgtcgacatg cttggtaatg gctatccaac aaataatgat
     8581 gcagcacaag tatatgactt ggactttaca gcgggggagt aatgtcccct gcaattggtg
     8641 agataacacc gacgactgat ggggcagtca ttaatctttc gtaaatgggg ttagagtatg
     8701 aacactgaag aatttataaa agaatataag gcccgatttc gtattttcca tacttccgaa
     8761 gatgaggata tcgggaaaca gttagagagc gggtttgccg atataaaatc tctaatcggc
     8821 agttttgatc cttccactta tgagaaagga aaagaattag tttatgaacg tactcggtat
     8881 ctacggaacg aatcactaga gtacttttac gacaattttc aaacaatgat tatggatgca
     8941 tcaattgatc tggcaggtgc tggatatgcc aattaaatca aattataaga agcctaaaat
     9001 tgtagctggt gatctaaata cgccagttac tttttttgag tttcaaccta ataagggtcc
     9061 agaacctggt gatgaagaaa aaaaggaact gtatttttgt acagcactag tttacaaccc
     9121 atcaatgaaa gatcgtgaca ttcttggcac aaaagaaggc gttacgataa aaatacggga
     9181 tccccatcaa tcttatattc ctactaacaa acataaagta aggatattag attatcgata
     9241 tggagataaa gtttgggaaa taatcgatgt ctcaccggat ttggaagaaa attcaattgt
     9301 aaagatagta ttagaattaa ttacttaaat ttggtgataa atgatgagta acgtaaagtt
     9361 tgaaggcgtt caagaaacaa tccaagcttt agaaaaaaag tatggagaaa agaaaactaa
     9421 gacattaaca aaaaaagcaa tcaatgttgg cgctgaaaaa gtagaaaaac agttgcaaac
     9481 ggacatgacc gtttttaaag acaaaggtta tacgatcgct gaggttgttc gcaagaacgc
     9541 tacgtataga gattacaagg cagaagctga aatcggttgg aatggtccac atcaacgata
     9601 tagaatcatt catttgaatg aatggggata tacacgaaag ggcaaacaaa ttagaccgag
     9661 aggatttggt gtaataacaa aatctcttaa gaattccgag ctgttgtact ttgatgctgt
     9721 aggagaggag gttaaaaaga gtttatgaaa gatatgctta atatcattta cgaggctctt
     9781 tgtttgaatg agtatattca ttcaatgacc tacaacgaga ataccgagca atatcgtatt
     9841 aaattttatg agcaacctga aaccgccgat aaaacaggtc caatgatcac aattcgtcct
     9901 gtagatacac ctaacgaagc gtaccacgga agtaacaaag agctttctgt ggagcatatg
     9961 atacagattg acgttgaatc gaaatataga gcaacatgca agcagattca atatgagata
    10021 aaaaaagaga tgaaaaaact aggctttggc caaatttccg gtcaagggtt agatgaatac
    10081 tttactgaaa caaaccgctt tgtagacgcg cgtcgttacg aaggaaatac aaaaatttac
    10141 gataccgaat attagaaatt aagacacgaa aataacgtgt ctttttttat tacccaaaat
    10201 taggaggaaa attttatgac tttagtagga ttcaaaaaaa tgacaatcgg ggtctttgac
    10261 agcacaggga agattccagc agcaaattta tatgtaattg aaggtgaaca aaacaaaggg
    10321 gcgactgtat ctgctgaaat cagtgggcta tcaaaagaac catcaaaagt ttacggatcg
    10381 aacatcgctt actatgtctc tcaaaaagga acaggcgatg tttcagctac ttttggattg
    10441 ttagatttac caacagaagt aaatgacaaa attcttggtt acaaaaccga tacaaacaaa
    10501 atcagcttct tgggagaaga tactgagcca ccatattgtg caattttgat ggaatcggag
    10561 gatttgaacg gcgatacagc aatgcttgcg atgttcaaag gaaaattcag tcgtgaatct
    10621 attaatctta acactacgac aaatgaagct ttcgaaccag aagcagaaga atatgtattt
    10681 tcagcgattg ccaatgatgt tgaaggtgat gctaaaggcc aaacagtcgc aaaatatgtt
    10741 ggagacgaag aagcttctat tactggtttg aaagagatgg tatttcctgc agcgggggag
    10801 taactagccc cgttgttgga gcaatcactc ccactattaa tggggcaaca gttgaattaa
    10861 gttaggagga taactatgcc agatacattt aaaatctata aaaaaaatgg tactgaattt
    10921 acaaaagtcg cagagggtga aagtccactt tctattactg gaattgcagc aaatactcaa
    10981 gttgctaaag gagattatca agctacgcgt gtggtcggag gtcaagaatc agtaaaagta
    11041 gatattcctg cattcaccac tcttccaatt tcagttactg gtgtgacgtt ggataaaacg
    11101 acagctgaag ttgaacaagg cggaacctta aaattaactc ctactgtaac accagcaaat
    11161 gcaacagaca aaacaggaag ctggagcagt tcgaatacag ctgtagctac ggttactgga
    11221 ggcaacgtta cagtaaaaac agacgctgaa gttggcggaa ctacagaagt ttcatttact
    11281 actacggatg gcggtaaagt agcaaaatgt actattacag ttattgaaaa agcagcgggc
    11341 tagtcttcgg actagctttt ttatttggaa aataatggag gaatctaaat ggcaaaagta
    11401 agaattgaat tgaaagaaga atcaggaaag aaagtctatg aaaacataga cacaacaggg
    11461 aaagattatc gaaaagcttt agaaacaatc aaaaagctaa atgaagacgg agtaatgatt
    11521 tggaatcgtt tagacattta tttggatttt gctgtaggta tcttcaggga tagcaaattg
    11581 acagctgaac aaattcttga tggcttacca tctgagaagg taatgagcac attggacgac
    11641 atcctaggag aagtaatggg gattgaaagt aatccagacc cagacgcaaa aaagtaacac
    11701 ccgaagaagc agaagaaatg tacttaaacc tatgcagaga gttagtgaaa gcgggatggt
    11761 cactatctga catagaagat aattcctttg aaatgatgat gaaaattgcg tgcacttcgc
    11821 ctaagaaaga gaaacaaaaa gaagttgatc ttaaagactt cttgaaatcc atgtagagag
    11881 gaggtaaaca tatggcaaat ggaaaacctt taggcaatat gattatcaaa ctagacttag
    11941 acagttcagc tttttcaaaa ggtctagccg gagctaaaaa cgctgttaac catcaaatga
    12001 aagcaatgaa atcacagatg caagtaatga actcttcagg aaattctctc ggtgctttac
    12061 aagcaaaata caatggttta ggcggagttc tacaagcaaa tgaaaagcaa gtagaattgc
    12121 tcactaaggc ttataaggat agttttgact ctaacggaaa cgctactgct tcgactgcta
    12181 aatacgctaa tcaattgaat caagcaacag ctagatcagc aagttacgaa tctcagatga
    12241 aaacaactgt tggacagatt gctcggatga aagtggaaac ggaagggttt acggggaaac
    12301 taaaggctaa ttctgatgta ttgattaatt ctgggaaaaa aattgaagcc tttggtaaag
    12361 gagtttctgg gataggatct gccctaactg ttggagtaac agctccaata gtggcaggcg
    12421 caactgctgt tactagtgca gctatttcat gggaaagtgc ttttgcaggt gtaaaaaaga
    12481 caaatgatga agttgtagac tcgaatggaa acgtagttta ttcctatagc gacttagaga
    12541 aaggtctgcg taatcttgcc acccaattac ctggtagcca tcaagaaata gcaaatgtag
    12601 ccgaagcagc cgggcaatta ggtataaaga ctgaaaacgt agttagcttc actaaaacga
    12661 tgatagacat gggtgaatcg actaatatgt cggctgaaac tgcggcaact tctttagcac
    12721 gatttgctaa tattacccaa atgtctcaaa aagactttga taaattagga tcagtcattg
    12781 ttgatctagg taacaatttt gctacaaccg aatcagaaat cactgaaatg ggattgcggt
    12841 tagcgggagc tggtaaacag attggaatga gccaaggcga aattctagga tttgctactg
    12901 ctctatcttc tgttggtgtc gaagctgaag cgggtgggtc tgccttttcg aaggtcatga
    12961 tccagatgca actagctgta gaaaaaggat ttggcgcttt tgatcagctg aaacagatgg
    13021 cagaagaaca aggtgttccg tgggttaatt tagtaaatgc tgtgagagac ggtggaaaat
    13081 cgttaaaagc agtatcagag caaatgggat tcacttcatc tgatttaaag aaaatgtata
    13141 aagaagcgga caattcgaaa agttcgcttg aaaattttgc gaatgtggca ggtgttacaa
    13201 gtgaacaatt ccagaagttg ttcaagagtg atccttcaga agcaatcatc aagttcattc
    13261 aagggctgaa agattcagaa aaacatggta cttcagcaat caaagttctg gatgacatgg
    13321 atataaaaga agttcgacta cgcgacagtt tattgagagc tgcaaatgct agtgacatat
    13381 tcaaaggagc aattgaaaaa ggaaacggcg cgtggaaaca aaatacagct ttaacaaatg
    13441 aagctaataa aagatacgaa acaactgaat caaagctaaa gatattgaaa aacgaagtga
    13501 ttgatacagc aatcgatctt ggaggtccat ttgtagacgc gttgcgtgat ggtctaaatg
    13561 tatcgaaacc attgataaaa aacttaggga atatggcgaa agctttctca gctatgagtg
    13621 atgatcaaca aagaaacatt atcaaatggg ttggattagc agcagcagct ggtccagcgc
    13681 tgaagctttt aggaactggt acttcagtaa taggtaaagt tacttcaact actggaagat
    13741 tgacgaaaag ccttgttgat ttagcagcga aagcagcaga aaagaaggct atggatgcct
    13801 ttgcatcgtc ggtaacaaca gctggtgctg cagctgcaaa gacagcagga gctggaggta
    13861 ttggcgggtt agtccctatg atgggaaaaa cagctagtgc tgcaagtact gctgcgggcg
    13921 ccagcggaat aggcgcaatg acaacgtcac taggtttgtt aggtcctgct ctacttggta
    13981 ttgttggcgt tggtggcgca ctggcagttg gctatggagc atggaaatta tttggtgaag
    14041 aagcttggaa ttcctcgcaa agagtaaagc aatggggaac agatgtcggt gaggagatag
    14101 atagtactct tgacggagta cagaagaata ttgaaggtgc aaatggtcaa ttcggtcttc
    14161 tcaaagaggg ttttactgtt gatgatgcaa ataatatggc ggctaatttc gcaaccgctg
    14221 gaacatcttt ggaaacatct ttaacgggta gaataaaggc attagacgat gcactaaaag
    14281 ggctacctca atcagttcag gatgccatga aagaagtagc tgaatcagaa gaagaaacct
    14341 tagggcaatc tctttctaaa ataaaagaca acaatgaaga aataaaaaaa atcagagaaa
    14401 gagccgcaaa tcagaacaga gacttgactg tttcagaact acaacagata caggatctaa
    14461 tgaaaggaac ttctcaagcg tatgtggata cgctcgatgt ttctgctaaa gacagaaaaa
    14521 agatactatc agccatgaat ggtgatgttg cacaagctac agaagaagaa gcgaagacgt
    14581 ggttacaatc tttagcgaaa caaaaagctg caactaccga aaattataga caaatgcttg
    14641 aagaaaaaaa ggcggcttta aaggaaaagg gagtaagcaa agaattcatt gatgcattag
    14701 aagatgaaat gaatgattac atcaaaacta caaatcaagg attcgatagc caaatagctg
    14761 ctataacaaa taaatatcca caattgatta acgaagtgag tttatcaaat ggtcaattat
    14821 ttagcaaaac ggcagctgct atggacaata ctggtcagta tacaaaagtt tttctcgaaa
    14881 gtaatgaaaa gattttagcc caagcgaaga aaacatcgga tgaaatagca gataatgccg
    14941 aaaaaaatgc agaacaactt ggtatggtag ctgatgaggc tacgcatgct ggatcaactt
    15001 ggaatggctt agttttagac gaaaaaacag gaaaagtaaa aactaatgta caagaagtag
    15061 tgaatgaagc aacgaaggat ttcactaaat ggaatgaatt gaaacctgtt gttcatgatg
    15121 cgaaactaac aacgaatgca aaagatgtca tttccatagc ggcagtacaa aatggctatt
    15181 gggatgatat ggaatggaaa gaaaaagaag cattattaga agatgagtgt tctaaaaatg
    15241 tatacaaggc tttagaaaat gctggtaaat ggaatgagtt agatattcct tctaaagaag
    15301 caatcctaac ttcaaatact cctgaagtta tgggtgaaac tctcatgaat ttgggattat
    15361 gggatactta caaacttcaa gtgaaagatt tagatttgaa tgcgtataaa gtatacgatg
    15421 ctatcgatgg atcagaagaa aaattaaata gttgggctca attagataac cccacaaaag
    15481 aattgttatt agataactca gatttttcta caaaactttt taattccgaa gaaatgttta
    15541 aacgttggaa tcagttatca tctaatgcaa agtttctttc ggctaataat actaaattta
    15601 cagaggttct tttatcatct gacagaatgt ggaatcaatg ggtaaacctt cctgataatg
    15661 agaaaagatt acttgcagat aacgaagatt tagctaccac tgttttatct tcagaagaaa
    15721 tatacggaag atggactcaa ttaccagata atcaaaaata tatgttagct gacaatactg
    15781 acttagcaaa caaaatattc gcttcagaag aatcatggaa tgcatggaaa gcaattccag
    15841 acacagttaa aaacttgctt ggtaataata ttgatttact ggctaaagtg aaagacggga
    15901 ctgtaagtgt agaagaatat aacaaagtta tgccacttct taaaactcta tatggagata
    15961 acgttaattt aaaagaggca atcagtgggg ctaaaagctc tatagagaat tacaacaaaa
    16021 atatttttcc tagtgataaa actgcagtag gacacgatga ggcttcacaa gctgctaaag
    16081 atgcatttga agcgttcaac atcttccaaa caaaaatacc agataaaatt actaaaactg
    16141 tatcagctga ctttataggt cctatgccga aaaatgcgaa aggaacaaac ttccatcctg
    16201 gcggagcagc tatggtaaac gatcaaaaag ggcctactta tgaagagctt ataaccttgc
    16261 caagcggaga aacttttata cctaaaggac gtaatgtcgt tttagactta ccaagaggtt
    16321 cgaaagtact gaacgccact aaaactaaac gtctagtgcc taaatatgct gatggtatag
    16381 gaaacataac gacggtttca tctacgctaa acttagatgc tttaatttta gctattaacg
    16441 agctaacgac ggtattgaga actcaactga tggcaggaac gactgatgct aaagatacta
    16501 aactatcaga tgaaacaaaa gttgccgatc cgattattcc ggacagtctt tctgaaaaat
    16561 cagatcagta tctaggaatt ggagctcaat ggttaactaa tctaatgaat ggttggaact
    16621 cagcggttcc tcaatatatg aatagtgaaa tggtttttat tacaaactat ctcaatgcgc
    16681 taaaacttca aaacaatcct aattatacgc aaggagcaac atggaataag aacttactga
    16741 atggatggaa tagtttaact gggaccttta ttgctacaat caattcattt tgtaatcaag
    16801 caatggtcac gcttagaaac tacaacactc ctatgtacaa caatggccga acgtggcagc
    16861 aaaataatct taatggttgg aattcattgt atggatcatt catagcccgt gtaaatcagc
    16921 ttggtaacga ttcgattaac aaccttcgtt ctaaaagtgg tggtttttac aatgcaggga
    16981 cattcttgtt gcaatcttta ataaacggaa tgaattcgtt aggtaattct ctttctacta
    17041 caatgaacaa tgtcgctaat acaatggttg gtggtatagg caaaggagtt aatggcgtca
    17101 tatcgggagt taactatgtg cttaaggaag tcgaatcaag taagaatatc ggaaactggc
    17161 caattccaca atacgctaag ggaactgatg gacatcctgg tggacttgct atgattaatg
    17221 atcaaaaagg cctagttcac gaagaatatg ttcagatgcc agatggacgt agttttattg
    17281 ccaaaggtag agatcttctt gttaatttgc ctaaaggtgc tcaggtctta aatgcttctt
    17341 taacaaagaa attaaaggaa cgtttaaata ttccacacta cgaaaaaggt attggcaatt
    17401 tagatattgt tgatttgtta gatgatgaaa aaagaatgtt agaattctta actagcaaag
    17461 ttgatttttc aggcattaat gaaccatggc ttgatatgac taaatcagga acgtcattaa
    17521 tgtccaaagc tgcaaataca atgcttcaat caaaattaag tgaattcttc actcatggca
    17581 attttgatgg tgcagtaaat gccaatggtg tttatcaata tttagttgat gtggcacaga
    17641 aagtaatggg taagttcccc ggacttacag taacttctgg atatcgagca ggagatgcct
    17701 actatcacgg aaaacggcaa gctatcgact tggcttatcc aggtatttct ggagatccga
    17761 gatatacagc agcagcaaat tacgcttttg aaaaattccc ttcaaaaatt gcgtatgtca
    17821 ttacgaatgg acgtgtacgt gaccgcatgg gattatctgg aacaaggtca agcggacaat
    17881 ggacgaattg gccagatggc gatcacttcg atcatattca tttaaacggt tcgatggggt
    17941 ctggcgatat attcaatgga ggagttggag gaagtggtgt tgcacgctgg cgttcttatg
    18001 tgtctaaagc attgaaaatg aatggattac cagctacagc agcgtatata aatgcctgga
    18061 tgtcccaaat ccaaacggaa tctggtggta atgagaaagc aatcggcggc aatgatgggc
    18121 tcgccgaagg caatgcaaca ggattacttc aaacgaaacc cggaactttt gcagctaacg
    18181 cttttcctgg tcacggaaat attatgaacg gatttgataa catgttagca gcaatcaatt
    18241 atgctaagaa acgttacgga gttgcaggta tgttgcaagt tatcgggaaa ggacatggat
    18301 atgccaatgg cggcttgatt accaaagacg gactatatcg agcaggagaa ggaaataaac
    18361 cagaaatggt tattccattg acaagaaaaa caagagctat cgaacttatg ggtcaagcat
    18421 tagccttcct ttctggaagc aataaaaaag aaacgaaaag tgagattaat tctgtagata
    18481 atagacatat cctacaagcg atagaaaaac agtctcgtat gacaaatgat ctgctatcat
    18541 tattactctc gttttttaaa agtaacaatc gatcagataa agaactagct ttagatattc
    18601 agaaaatttt aatcaggagg acatagtatt tgaggacagt aatattaaga aataaattga
    18661 atgaagaaat tgatttgtcc acagaagatt attttgctac tgaaatgtcg aatctaggtt
    18721 ttgaagttac aaaagagcat attggacaat gggggagttt cagagaaata ggagagagta
    18781 ttgaattgtc tgaatttcaa tcatcagtta tgatttctgt tcacggattt agagaacaac
    18841 aattatatgg ttcattagtt gaatttctgg ctaatggacc ttttgaacta gaattttctt
    18901 ttgattcaga aacaatgatc aggaaatgta gtttgaaatc attatctaaa acagaaattg
    18961 attcccaaag ctcattgcta acagatactt tgaatctata ttttacttca agctggtatt
    19021 ctattaagcg tgaaaaatta atacagaatt caacttctct caatacacgt ggaaaagttt
    19081 actcatttgt tcgaccatat gtctacacca aaaatgtatg ggaaaagaaa ggtgtattta
    19141 agttcagtaa taattctgta tatttgacaa atagtacaga gcgaatgtct ccgttaaaaa
    19201 taaggattat tggagagtgc tcaaatccat attgggaagt tatccaaaac tctaaagtag
    19261 tagcttcaga tggctatttt attaatatga aagacacaca aatattagaa gtgtctagtt
    19321 tgctagaaga ccaaacggca attttaaaag atgtaggtgg agttgaatct tctgtttatc
    19381 aacaacaaga ttttactaaa tcaaacttcg tccaagcgcc tctaggagaa ttcagcgttg
    19441 tttttcatgt tggacatgca aatgtagaga ttgaacttta tgaggagcgt gatctatttt
    19501 gattttagcc attaccctct ttcaccgaga tatgaattta tataacgaac gtttaatttc
    19561 gactgagttc gaatttggaa cggatgaaat tggagaagaa gtaagtaatt ttattacaga
    19621 taaatatgtc catgtaaaat caggagattt tctactagca aaatttattc ctagcgggaa
    19681 gattgcttat tttggagtga ttagctcgca agaagacaaa aaaataaatt gcaaaggatt
    19741 actcagtttg gccgatagcg agataccgac tgtaaaaata tcaggtgcta attatgaaga
    19801 gcatattcga cgactgattg aatactactt attgaacgat ccaacaaaac aactaaaaaa
    19861 tattttggag gtaaaaacag aaagcgttac ttctcattct tatcaagctg ttgacacaaa
    19921 taagagacga ttgaatgcat atataataaa tgggttcaaa aaatataatg ttaaatggta
    19981 tgtcaaagag attaaaggta aaaaaatata tactggtatt cgagcagttg atgattcaat
    20041 ttatattaaa gataattcat ctgagtttaa tgactgggat gtttttgtgc aatctcctgg
    20101 accagggaac gagaacaaat tattgatcgt agataaagca atgaaagata tagaaaatcc
    20161 cttggtattg tctacgtggt atttagatga cgaaaataat cttacgcaag attcaacgaa
    20221 taagaacatt gcattgccta ccgttaattt agtaaatata tatgatcaaa ctcaagaaga
    20281 tagaccttct tatgaagagg tagctaaatc ggagcttaaa ggcaacgcct attcacatga
    20341 aattaaagtt aatgttgtgc taaatgctag aaatatcaat gtagaaaata tcgaaacagg
    20401 aatgttagcg actattgttt acaaagagca gacttacaaa tctgttctaa ctgcctggcg
    20461 aatatccagc agtaaaaaga atatagaatt gacatttggt aatgtccgaa gtcgttttat
    20521 ggattatttt gaagataatg ggggataaaa aatggttagc aatgtggatg gatatcaatt
    20581 tgaaaacgtg aaagtaagcg cagaaaatga tgctagactt tatcacgttt tatataatcg
    20641 gaaaaatcag gttattgatg gttacgatca gtctatgaat ttatcttcaa gcggattaac
    20701 agtaaaagtt gctgcaggag cagcgattat tcaaggtcgt atggtcgttg ttcgacaaga
    20761 agaaagtata acagttccag caaactcaag tggttatata gcattaacag tggatttgac
    20821 acaagaagtt atacctggat ctattcttcc agaatcggaa gaatatgaat ggactaataa
    20881 tcaagtcaag ctagaattta taacaaaagt tataaaaggt aatttaaaca atggtgataa
    20941 ggtctataat ttaccactat gctcagttaa ttctactgga tcaactgttt caatctcaaa
    21001 gatatcggat agttacgagc tgactctctc taaaggagaa attttgtgga gggggactgc
    21061 gttaatgcat gatactcaaa ctgtccaacc ttcaaaaaaa atttggcaga cagtttcagg
    21121 ttttttgtta gtatggctcc catacgaaaa cgggcaagca attgaggata gatatgtaac
    21181 tacgcctttt tataaggagc gtataacttt tactaatgtt ttaggagaaa ttgtttcagg
    21241 atttgatgac tatcacaaaa agtggtttag taaacgaata aactataatt cgaatactaa
    21301 tatatttaca ggtgcagcaa gcaatgcaag tggagataac gcaaatatgg tgcttaggta
    21361 tatagtttct ttttagttag gaggtatgga agagtggcaa atttagaaat taaattatct
    21421 gcaaataaga gacagcctta tctacgtcac cgtgttgttg gtagagttgg tgatgggggg
    21481 ctcacaacaa tcaatgtaca acttcttgag gaagatgaaa ttacaccttt tgtaattaat
    21541 ctaaacggta ctttgaaatt tgtgggcgaa gtttcaaacg gtaactatac cgagggagaa
    21601 ccagaaataa tcgattcgac taatgggtta attagttaca cgttcactaa gtcaaatttc
    21661 agcacgagtc atcaattcaa acaagcatat tttgaatatg tagatcctaa cggcaaaaaa
    21721 gtaacttttc agaacttcat catagacgtg ttagaacgag tagatattaa ttcggagcaa
    21781 gcgaaatact atatttcttc attggaaaaa ttacagagtg aaatgcaaac cactttcaat
    21841 cagttcatta gtgataaaca ggtccaatac gatcaaatct actcgaaata taacgaatta
    21901 gtaagattga taaatgaatc agataagcaa gtaaatgatc gtattgataa ggcaaataat
    21961 cgtattgatc aaaccaatca gcaaatcggc gatctcggca agctgaaaaa gatgtacagt
    22021 aacagcattg a
//
LOCUS       DARBDN010000038        21977 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000038 DARBDN010000000
VERSION     DARBDN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.038"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            16..1653
                     /locus_tag="SCH06_001431"
     CDS             16..1653
                     /locus_tag="SCH06_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078016.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1798..2538)
                     /gene="truA"
                     /locus_tag="SCH06_001432"
     CDS             complement(1798..2538)
                     /gene="truA"
                     /locus_tag="SCH06_001432"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEG1078017.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2729..3364)
                     /locus_tag="SCH06_001433"
     CDS             complement(2729..3364)
                     /locus_tag="SCH06_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEG1078018.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIARLSILHLKQ"
     gene            complement(3511..4752)
                     /gene="sstT"
                     /locus_tag="SCH06_001434"
     CDS             complement(3511..4752)
                     /gene="sstT"
                     /locus_tag="SCH06_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEG1078019.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4950..5948
                     /locus_tag="SCH06_001435"
     CDS             4950..5948
                     /locus_tag="SCH06_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078020.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            5961..7979
                     /locus_tag="SCH06_001436"
     CDS             5961..7979
                     /locus_tag="SCH06_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEG1078021.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8039..8755)
                     /locus_tag="SCH06_001437"
     CDS             complement(8039..8755)
                     /locus_tag="SCH06_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEG1078022.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(8982..9524)
                     /locus_tag="SCH06_001438"
     CDS             complement(8982..9524)
                     /locus_tag="SCH06_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEG1078023.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9529..9756)
                     /locus_tag="SCH06_001439"
     CDS             complement(9529..9756)
                     /locus_tag="SCH06_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEG1078024.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(9835..11715)
                     /locus_tag="SCH06_001440"
     CDS             complement(9835..11715)
                     /locus_tag="SCH06_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEG1078025.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(11904..12518)
                     /locus_tag="SCH06_001441"
     CDS             complement(11904..12518)
                     /locus_tag="SCH06_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078026.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            12660..13220
                     /locus_tag="SCH06_001442"
     CDS             12660..13220
                     /locus_tag="SCH06_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1078027.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13525..13839)
                     /locus_tag="SCH06_001443"
                     /pseudo
     CDS             complement(13525..13839)
                     /locus_tag="SCH06_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14093..15728)
                     /locus_tag="SCH06_001444"
                     /pseudo
     CDS             complement(14093..15728)
                     /locus_tag="SCH06_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16283..16846)
                     /locus_tag="SCH06_001445"
     CDS             complement(16283..16846)
                     /locus_tag="SCH06_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEG1078028.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(16861..17904)
                     /locus_tag="SCH06_001446"
     CDS             complement(16861..17904)
                     /locus_tag="SCH06_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078029.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(18037..18441)
                     /locus_tag="SCH06_001447"
     CDS             complement(18037..18441)
                     /locus_tag="SCH06_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEG1078030.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(18674..19309)
                     /locus_tag="SCH06_001448"
     CDS             complement(18674..19309)
                     /locus_tag="SCH06_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEG1078031.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(19575..20627)
                     /locus_tag="SCH06_001449"
     CDS             complement(19575..20627)
                     /locus_tag="SCH06_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078032.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(20640..21578)
                     /locus_tag="SCH06_001450"
     CDS             complement(20640..21578)
                     /locus_tag="SCH06_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEG1078033.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
BASE COUNT         6953 a         4322 c         3470 g         7232 t
ORIGIN      
        1 aaataggaga aaaaaatgaa aaaaaacaaa aaccaaataa tagatatcat ttttatgtta
       61 tttctaagtt ttgcttacgt catccctcta ttcatgtcta agggaatcta tcatagtgtc
      121 aatcaggata cttactttca tttatctcga atcataggac tagataatgt atggagttct
      181 ccagtaaact tcaataactt cgatcatcat ggaacaatga tgaatatttt ttatccatgg
      241 cttactcttt atccagcttt tttattttat aaaatgatgg gaaatcttgt tttaagttat
      301 aatatctact atttttttat cactttttta acaatggtcg tttcttattt ttctatgaaa
      361 caaataaaaa acaatcgtta tatttcgctg ttattttcga ttatttatac attttccgcc
      421 tatcgtgcca ttgacatatt ccatcgtgct tcattgggag aagctgtcgc tttaacattt
      481 ttgcctttga tactaatggg gtgttacgaa atttatatta gagattacca aaaatggtac
      541 tggttgtcta ttggcatgac gctagtagtg tatactcatt tactttctgt cgctatggtt
      601 tctgtattta ttggaggaac gttgtttctt tctttttatt tttgggacca aaaaatcgct
      661 agactcttaa gtcttttaaa agctaccgtc ctcacctttt ttttaagtgc gggattctta
      721 attcctttta ttcaacaatc tagagcacaa gaattgaaag tcccactggg aaaagaatta
      781 agtggtatgg ctcctagtga tatgctgaca catattttaa ataataacta taacaactat
      841 actattggat tattcttatt tctcggattg attggtgctt ttatttttat aaaaaaatta
      901 actgctgatg atttatttat tttctttctt ggtgtatttg ttcttttttg ttcaaccaat
      961 ttatttcctt ggcaactttt taaccataca ccagttaaga gtctacaatt tgtctggcgg
     1021 ttaaatggtt tttcttcttt atttatagcc tatacgatga gtatagtgat ctattatatt
     1081 ttttctacta aaaataattc atggaaaata atggtcttta cgtttcttgc actaatattg
     1141 catctctcag gagtaagcaa ttctatccat gctaacaaag attcattaac acttatagca
     1201 cctgaagacg ctgttgctat agctgaaaat tacaatcata ctgattatgc aaacaaagag
     1261 tcaatctatc atcctgatat gattaataat gatcaatatt tactaggtaa ccaggaaata
     1321 aatccaacaa ctcattttat gagtaacaaa cttacaattg aattagataa ttcgaataat
     1381 aaaaatactg tcttgacgac acctatttat cgttataaag ggcaagtggc ttctattaat
     1441 ggcaaactag tacaaacaaa attatctaag tttggcacaa ctgaattaac tattcctcca
     1501 ggtataaata aagtcgttat tacttatcag tacacaaaac tagcaattgc ttcaagatat
     1561 ttatctatcg ttactttgat tttattttta ctttatcgat ttactttttc taaacaaaaa
     1621 caaccgagaa gagaagtaca acattctcac tagattttta tttaagaaag actttttagc
     1681 tgtacacata aacaggctaa aaagtctttt tttatatttc tttaatttgc ttcatacatt
     1741 atttaacatc gatatttata ctgtgaaaca tgcgtttcat ccattatcaa agtattttta
     1801 tcgataataa acttcatcca aaaacagacc ttgtgcaggg acggtttctc ctgcatgttg
     1861 ccgcactttg ctttcaaata tttcatcgat tgtttctatc ggcatggcac ctgtgccgat
     1921 ttctagtaat gtccccatga taatccgcac cattttatat aagaatccgt ctccgacaaa
     1981 agtaaaatga agcatttctc cctttcgttc gatagataat tcatcaatcg tacgcactgt
     2041 ggattttttt gattttttca atgcagaaaa accaatgaaa tcatgtgtac ccactaattt
     2101 ttcgcaagct gcattcagct tgtccatatc caactcttga gggaaataaa agctgtggtt
     2161 tcgctcaaat gctgaaggaa tcacgttgtt ccaaacataa tagctgtatt ttttgcccac
     2221 cgcattatat cttgaatgga agcgctcagg catttcttcg attcttttga tgacaatatc
     2281 ccgcggaagg taacgattca taaagtcgat catttctgcc agtccaattt ctgtgtttgt
     2341 tttaaaattt gctacttgtc ctcgcgcatg ggtgccagca tctgttcttc ctgatccaat
     2401 aatttctatc tcttcatttg tcatctgatg caatactttt tcgatttttc cttgaatggt
     2461 tttatcgtca tctccaagtc tttgccatcc tgaatatctt tttccgtcat attcgattgt
     2521 caacttgatg tttctcatat tttagtggct cctctgtctt ccatttggtc ttctctctac
     2581 ctttttaaga ttgtagcaca aaatatagct ccttgcttct ctaagacaga agctatacaa
     2641 gaaaactgtg gaaatatata tttcagaaaa acaaaaaaca gccaccggat gaagtatccg
     2701 ctgactgttc aatttgacgg ctcaagtttt actgtttgag atgcaagata ctcaacctgg
     2761 caatgggcac ataattaaag aaaaaactga ttctttggca aaaacctatt ttattcagta
     2821 atggccaaga atttatagaa ggaattcttg ccagtccata aatcgccgca aaaagcaaac
     2881 tgatcacaga cagtccaagg tataagtggc ttacgtccat ttgcccattt tttcgataga
     2941 tcaagaaaag aagaactgga aacaataaaa aaccactgta acctaaacct gatccgatat
     3001 tatggaccca tgtcgagaca ttccacgaag attcatgggt attgatactg aacaaacctg
     3061 taaagataca atcacctata ccatagaacg cgatggctgc tgtaactagg gtagctaaca
     3121 cacgagatgt actaacaaat gcagcataca atgcaggcaa tgacaggatg aaaaagatcc
     3181 ctgaaaccac agaccaaata agaaacgctt ttcttacagg actggaaacc tctccaaata
     3241 cactgatcac gctcttcatt tgatctaatt caggataata caatcctaat acgtacggag
     3301 tcaaaaaatc actcagcacg cctaataata aaaagaaaaa accaaattta cgtaaaaaat
     3361 ccatgatacg cctccaataa caattaccta tgcttttaat tgttattata aacgacttta
     3421 tcttgattta acagaaacct ctatttacac gaacatctat ataactcatt aaaaactcga
     3481 atcattttaa aaatactaaa tatctaacgt tcaacgttca cttaatccat ctaaacaatc
     3541 tttcaatttg attttttccc cacttctttt acgcgcgcct agctctccta ttgcagtaaa
     3601 caacagatca cttgacgaat ttaaggcagt ttccattgaa tcctggataa caccgataat
     3661 aaatccaata ccgacgattt gcatcgcgac atcattagag ataccaaaca aactacatgc
     3721 taatggaatc aataacagtg aaccgcccgc aacacctgaa gctccacaag cagctaaagc
     3781 agacaaaata cataaaagga ctttcaaaac aaaaggtgct tcaatcccta aagaatgtac
     3841 agcagtcaac gtcatcaagg aaatggtaat cgcggcaccg cccatattga tcgtagcacc
     3901 taacgggatc gatatggaat aagactcttt tgtcaatttc aatctttcag ccaacatcat
     3961 gtttatcggg atatttgcgg cagaacttcg ggtaaagaaa gcgggaagtg cgctttcttt
     4021 caaacaaaag aaaatcaatg gatagggatt ttctttaata aacaaaaacg tgaggaatgg
     4081 gtacacaact aatgcgacaa acagcatcgt accgatcaaa acaagtaaaa gctgcagata
     4141 ctctgccaat ccagcgattc cagtcgtagc aattgattga taaaccaatc ctaaaatccc
     4201 tatcggagca aatgcaataa tcacttgtac gacttgtgac aacgctatag atatctgatc
     4261 caccaactct tttgtcgatt ctgaacgtgc tcgaaaagct agtcccaaca atacagccca
     4321 gaataagacg ccaaggtaat tcgcatcaat aagagattga acaggatttt gtgtgacatt
     4381 cgtcaacata gtagataaaa cactttccaa actttgcggt gctttttcag atactgtttc
     4441 ttgtaaagta ataggaacag taaaaattga acttacaata actgctacaa gtgcagaaag
     4501 caatgttccc actaaatata agatcaaaat aggcttcacg aatgtcttat tcccaatttt
     4561 atgcttggca attgacgcca tcgtcaagaa aaaaaccaga ataggtgcga ttgccttcaa
     4621 gcaactgaca aacaacgttc ccaatattga aataaatgtc catgtgggga aaaagatacc
     4681 aaacaatatt ccgactaaaa taccaacaac aatacgttga actaacgaca tatccaaaaa
     4741 cttctctaac aaatgaccac cctttcacaa ttttaacaat cattgtatca ttttatgcaa
     4801 agaaactaaa ggtataattt tctaaaaatt ctaacaatac aaacaaccat ttcttgctaa
     4861 ttttgtactt tttctgtcta cacgttgttt tttgagatat tctaagttag gatgttatta
     4921 atgggcaact tatcaggaaa cgttttctta tgtttttgtc caattttttt gtgaggtgtt
     4981 tattcttgaa aaaaataaag aaggagagtt atggcttcct gacaatcttt gtcgcttgta
     5041 taatgatggt tttacagcgt atattgattt cagcagtcac tattcctaca tatgcaacaa
     5101 accctggtcg attctacatc tatacatttt tacaaacttc cgttgttatt ggtgcaaatt
     5161 tgatcccact ttacatgggt taccaatatc aaaaaatcgc ccgtttaaaa gttttacatt
     5221 atttaagtcg ttttgccttt atattcctaa tagccacact agtttgcaat atcttttttt
     5281 acgtacaagc tggcagcttg aatattcgtg attattggct tatcctaaca cctatcagtc
     5341 agaattactt tacttatgct gtttcttgta ctttgctttt ttgtagtatt ccttatacag
     5401 ttggattttt aaataaatta tcgaaaacaa caattaaata tctactatta tttttaacaa
     5461 ttggattagt tggctgctct actctattta ataaagaccc gtttgcatta cagaatggac
     5521 agagtatttt atggattttt tatttatttt taatgggtta tggtttgaaa gaatggaact
     5581 ggaaagaaaa ggtccgctat aagcttcctc aagtatttat cagcttgatt gttttattcg
     5641 gtttgattat tttgatgaca caaatttcac tcatcatcag aggaaataca gatacagcgc
     5701 tgaggttttc taaaccatat tctctcttcg caatgtatta tactttctct tcgtttttat
     5761 ttttagaaat gctatctgat aaattaggta taaaaggaag aggaaatttt cttgctgtat
     5821 ttttgattgt cactcaagtt atatgtaatt tccctttagt ttcttatcgc gtatctacat
     5881 ttatgaaacg tgaatttcca aactcaggga aggcatggct gataaatatc gggcagtttt
     5941 ttatttgata tttattagca gtgtccctcc tagttatctt tttattttat atacaaaaaa
     6001 tccgtttcat tcatcgtttc atcgaatact tcgcttttga ttcgattgaa caattaactc
     6061 agcgttggaa aaaaagaatt cattggcttt ttgttcataa aagttatttt ttagttgcag
     6121 cattttttta ctgctttacc ttcgtgcaga ttttcgtttt agaaccaaaa gaaggttgga
     6181 aagaaactat ccaggttgcc ttaaaaatat ttactcagcg acaagcaccc atgatcctga
     6241 caatcatcat tattatggga tttttcttct tactattgtt gatttccaat cgtttttggt
     6301 acgccttgac tgctaccttg atcattaact tactgctcac tatttcgaca gtaatcaaaa
     6361 tggaaatgcg ggaagagcct gtctttcctt cagatttaaa aatgctgacc ggattgtcag
     6421 aactattatc gatggttagc ccagtcttat taatcgtggg cggattgatc cttctcctat
     6481 tattgattac tagtattatt gtacaacgta gactacaaaa acagtattcc ttgaagattc
     6541 attggaaacg tcgatttatc agtatcgctg tattattagg atgtttttcg ggtgtctttt
     6601 tcattaatca caaaaattcg ccttctttct tgctgtttaa tttatttaaa gtaaacaaga
     6661 ctttctttaa ccagcaaggc gccgtaaaag ataacggacc agtcattcaa ttcctaaaca
     6721 atatcgacat taaaatcatg gaagaacctg ctggctattc gaaagaaaaa attaatggaa
     6781 taatgaaaaa gtacaacaca aaggcagatg aaatcaacca aacaagaagt gactggttaa
     6841 acaatcagac gatcgttctc aatttaagtg aaagcttcag tgatcctgca cgtgtcccta
     6901 atctgacagt acctacagac cctattcctt acatcaaaag cattataaca gaaggaacag
     6961 gaggattgat gttatccgtc ggttatggtg gcggaacagc taacatggaa tgggaaggac
     7021 tgacaggctt gagtatcagt aacctgtctg cttcgttagt tacaccttat acccagctag
     7081 tggagcgtca gaaaataagt ccaaatatta ccgatctatt cgatgaaaaa atagccatcc
     7141 atccttttac agctgctctt tatcgcagaa aacaagtgtt tgataaattt ggttttgaca
     7201 ggttctatta tttagacagt ccggataaat taacttatac ggataaaata gaacaaagcc
     7261 cacgcatatc ggatgattca gcatacaaag aaaccttgaa agctttacaa agcaatacgg
     7321 aaacgtcaca attcatccaa ttatccacta tgcaaaacca tatgccttat gatgattact
     7381 atagtgaatt gaactacact gctgaaggaa ctgctgtcat tcctaataga agaaaagaat
     7441 tacaaactta tatgcaaggc cttcactata ccgatacagc agtaaaaaaa ttcatccaag
     7501 aaatcgacaa aatcgataaa ccgattacct ttgtttttta tggtgaccat ttacccgcaa
     7561 tctatagtgg gaatgattcg aaaaaatatg gattagaaca gcaccagaca gattatttca
     7621 tttataacaa caagtatagt cgtgaacaag cagctacgtt aaataaagaa gttgttgctc
     7681 ctaataactt tggtgctatg gctcttgagc atgcgaatat caaagtaact ccttactatg
     7741 cgttgttgac agaagtatct aatcatctac ctgcattaac aattgatcct acagaaagct
     7801 tgtctaatcg ttttaatgga aaacaggtct ttgttacaga ggatagtcaa attatccaag
     7861 aaaaaaattt aactgagaaa caaaaagaaa ttctagaaga ttatcgtctg atacaatatg
     7921 atcttgttgc aggtaaccag tacagtgcaa catgggcgac acaaaaaata aaagactaac
     7981 aaataaactg agcaaggggt tgtgataaaa gacatgtcac aaccccttgt ttatctcatt
     8041 aatttgcttg tccataaacg atttgattaa agccattttt caattcatta ttcgctgtct
     8101 cgttgaagta aagataatta tcgggattcc cctgattttg ttgtgtcacc aatacttttg
     8161 gctgattttg ctgaaacccg aatagataga cgtgcttttt cagatatggt tctgtctctg
     8221 catcggaata gacggctgtg atttgatagt ctgcttgacc tgtcccactt tctgaccatt
     8281 ctgcagaaac aggcactcca ccaatagcca tcttccactc cccgttcaaa atagcttgag
     8341 ggactttaag accatataag tccacactca tttgattcgt ataacttttg tattgttgtc
     8401 ccattgtttg gccccatttg gtcataaatg cctctaattg tgcggatttg tctgcattcc
     8461 acagtgtttg ttcaacttgt tcgctgcttt ctgaagagga agatgaagcc tctacagaag
     8521 aacttgaagt agatgtttga gttgtttcag tcgttttgga agactctgac gaagtagagg
     8581 tatctgctgt ttctgtactt gctgcagttg acttgctctc tgtgctagtt gttgtagtag
     8641 ttgcaactgt tgctttcgct gtttcttttg ttgattcttt tttcgattca ttcccgttgg
     8701 tacaaccagc taacaaaaaa gctagaccaa ttgttactaa aatccttttt ttcaattaaa
     8761 aaactccttt cgattactcc cacttcttta ttctatcaaa taagcaatgt gattttattg
     8821 atttttcgta ttttctcatc aatctttcaa atcttctaaa aactgagaag cacccgctga
     8881 tgttgtctgt aatacatcag cgggtgcttc ttttatttta atcttcgtga ttttccaatt
     8941 tacctcacgc tttatatttg tatttgaaga aacatagact tttagtcatc atcgtcttcc
     9001 tcatccaaat cttgtcggac agtttttcct tggagtcttt gtacttggta gatgatttct
     9061 ttattgaaac ttaaaagttc aacaagcaat tgttgcaagc catatttttc ttctttttca
     9121 gctaatttga ttgcccgtgt gataaagaca ttttggaaat caaaatcttt tgcaaagttt
     9181 tccaacattg ttgaggctgg taaatatttg ttttgaccat gttcgtaaat ttttccataa
     9241 cgcatgactt cttctaaagt agacggaacg atttcatttt caatcactaa ctcatgagag
     9301 attttattga accatctcgc ttcttgatca gcatattctg aaaaaagggt acttaattct
     9361 tgcgaagatg tacccaaaac atacaattgt gcttggatca atttcatttc ttctaattta
     9421 aaatttgcta atacatgccc caccatggcg ccagcagttg gtttatgatg gtcgatatct
     9481 gcttgttttg tttcttgaac aaatttttct tccactatat tcattgattt acgcctcttt
     9541 tacttttgct gattggactt cataacctaa tttttccaca actgcagcta attgttcagg
     9601 gtggacttca tctggatcaa agtttgcttt gattttgctc gcattaaaca aaactttcgt
     9661 attgcttacc ccaggctgtt gagaaaccgc atgttcgatt ttttgcatac agcttggaca
     9721 agctagtgta tctaattgca taataatttt tttcatcgta gttcttcctt cctttttctt
     9781 gatagtctta ttctagatta cagcttccat aaaaaaattg attcttatca agttttacga
     9841 tttttcttct ttgctttcgt gtccaaaata caataaacgc atcgcgttaa agataacgat
     9901 caagatacta gcttcgtgaa cgaacatccc actagccatg taaataaacc cggcaaataa
     9961 gccgttgagt aaaaataaga cgacaccaat ggcaatcact acattttcac gggtatttaa
    10021 aacagttttc ttagccaagc ggtaggcatg aaccaacgat tcaaaattag attgcatcaa
    10081 gacaacgtca ctcgtttcga tagcaacatc cgttcctgat cccatagcaa tcccgatatc
    10141 agccgcagcc aaagagggag aatcattgat tccatctcca ataaaagcaa cgcgcaatcc
    10201 ttgttcttgg tattttttca caaattgaac cttttcgtct ggtaataatt cagcatggac
    10261 ttcatcaatg cctaacatat cagctacata atcagcagtc atctgattat cacctgtcag
    10321 catcactaac tgttttgctc ctgcttgttt caacttagct aattgttcag cgacttctgg
    10381 tcgaatcaca tctgacacac ctatgatttg agtgattttt ttgtcgattg ctacaataat
    10441 gaccgagctg cctgtttgtt gtaattgatg taaatcttgt acttgctttg gtgtgagaga
    10501 aagtttgtga gcggcaatca atttggtgtt gcccgcacaa actgtatgac catcaatctc
    10561 agctgtgatt ccttgtccct tgattgtctg attatctttg actgctaatt gttgaaaatc
    10621 aatgtctttc tcctgagcat aatggatcac ggcgcgcccc agaggatgat cggataacgt
    10681 ttctaatcga gccactaaag ctaagctgtc cccttcatcc tctgtatagt tcttgatagt
    10741 ggatacagca gtagttcctt tggtcaatgt accagtttta tcaaagacaa aagtatcgat
    10801 tttggaaaaa gtatccattg cttcaccgcc tttgactaag atgccccgtt tcgctccatt
    10861 accgattcct gctacattcg aaacaggcgc accaatgact aaagcgccag gacaaccaag
    10921 aaccaaaaca gtgattgcta aacgaaaatc acgactaatc agaccaacaa ccaacgcaat
    10981 aagtaaaacg gttggagtat aatactgaga aaatcgatca atgaattttt ccgcatggga
    11041 tttggtatct tgtgcttctt ctactaattc gataattttg gcaaaggtcg tatcatctcc
    11101 gaccttagtt gcttcaatcg tcacgtagcc atctgctaaa atcgttccag agaagacttc
    11161 atctccactg attttgacga cttgtcgtga ttcaccagtc actgcggctt catccgcata
    11221 ccctttcccg tcaatgactc gtccgtccac aggaatagct ccaccagttt ttactaagac
    11281 gatatcgcct tcttccacgt catcgatttc cacttcttca gtcgttccat cttcttggac
    11341 aacactagca gtagatgggg ccatctcggt caaagccttg attgactccc gcgttttggt
    11401 caatgttttt tgttccagat agctaccaaa caaaaacaag aatgtaacga tagctgactc
    11461 cttgtattct ccgatcataa aggcaccaag cacagcaata gtaacgagta aatcaattga
    11521 gataactttg actttcactg cctgatacgc atggatcata ataggtatga ccgcaataat
    11581 agaagctatg gctagagcaa tgttatagaa caagacaaaa ccagtaaatt ttccgataaa
    11641 accaaaaata atcaacacag ctgataaggc ggtgatatga tttcgatgct cttggatcca
    11701 cttttgtaat ttcatctttc tccctctttt cctttcattc ttacgagact aagtatagat
    11761 acttatccat cataaaaaat tgaccactat caagtttagt caaaaaggcg gttttctttt
    11821 ggtagaatac actacaaaaa atagttagca agaagactca ctaaaagtga tcttgccaac
    11881 tattgtcgtt tctatcgaaa ttttcattga atgattttcc tgtacagcat acatcggaga
    11941 tctatttctt tatctaagat ttttatcttg ctaatttttt cctttagtct ttcaaatcca
    12001 cgtcgttcat agaattgata cgtacagcca ctatctgtaa aaaggaatat ttcttttcct
    12061 ttctctcttt tttcaaattc tgttagcaac ttggtaccga tgccttttgt tttcaaatca
    12121 ggatttgcag ctaaaaaaat gatctctcca tctggcgaat gcttctttaa atatgctgca
    12181 agcatttgtt catttgctgt ctcgtaagct cctttacttt ctttagcaaa tatattttgt
    12241 aaaaaatcga atatcttaac atatatttgc tgtccaaaag aacgatgttt ctttttttct
    12301 ccttttatct ccgccagcaa aacacctgcc aactcgtcct ctgcatacaa agcaagaatt
    12361 tgagttgctc gattcaactc catatacaaa aaatatcttc cgtaaagatt cagcagaagt
    12421 tcattttcca tatatctctc aaagttcatt ccttcaacag caaaatagat agcttttttg
    12481 taatctttct tttctaaggg tttaaaagtt agtttcatca tttcgcctcc tcaacttcaa
    12541 tgattgtgtt atacttacat tataatagac acagtgtcta ctatctataa tcaatcatct
    12601 ataagtttgt cgattaagcg acagctttgc tttgatatgt cggataagga gataggtaaa
    12661 tgaaaaagac agatagacgc gtcaaaaaaa cagaaaaagc tttggctgaa acactatcca
    12721 cattattagt aaataaaaag attcaagcaa tcactatacg cgaactaaca gaaacggcag
    12781 atgtacatcg ttcgactttt tatacacatt ataaggatat ctatgatcta tatgatcaat
    12841 tagaaagcaa cttttttcgg gatctaaatg aaattctctc ttatgatcca gcccatagct
    12901 atgaggaact atacactcgc ttgattgact atgtttacgc aaatactttt ttatatcgct
    12961 tatttatcct caaccatggt gatatttcgt ttcagaagaa agttaaacaa gttattgaag
    13021 aaaactatct gaacatatgg ctatatgaag acaagaaaac gattatcaca gaagaaatga
    13081 gattctttac tacgtaccac gtccaaggtt gtctatccgt tctcaatcgg tgggtagaaa
    13141 gcaattacaa gtactccaaa aaagaattat tagaactctt acagaaactg aatgatcaca
    13201 tagagaaaat catgccttga ataaaaacat actaagctta gttaagaaga accgtaacct
    13261 tctcgtataa caactgaatc ttatttagcc aaattgttta ctgaagattt tttgagtaaa
    13321 atttctataa ttcctactta ttgaaaagta gtttgtagtg ctgcttctcc ctctctaagt
    13381 gatatatctt gttgtaccaa tcaaattcac ctcatcatta ataaattact tttaggctaa
    13441 tttattacaa cttataggtt gaagctgtaa ccaatttata gtcatattat atttttatca
    13501 tccagtttat tgaattcttc tcgtttacct caattcattt tcaaggggaa tcagctcatc
    13561 atctaacatt ttacgccatg ctcgcttcat ttcttgtggg tatttaaatg gtttcgcttc
    13621 tggatgtttg gctttatatc cttcgtaatc cttactgttg ataattgctt tcatattagg
    13681 aattggatct tcacctggca tatattgcag attagaagca tgtaattttt tctcagaaac
    13741 aaaccactca ttggaaaaga catgaatcaa atcatcactt acttgtgtaa aatagcgacg
    13801 tttaatgaca aagatatctt cattgctatc tagtgtacct tcatttcttt gtgcttaaat
    13861 tcaaagataa ttttctcaat aaagattttt gattccagta agattccttt actcctttta
    13921 caacatagcg ttgtcctttg ttttgaaaca tcttcttccc ctctttgcca ttaaaaatag
    13981 cccaattctc tataaagaag attaagcttc attattataa tataaagttt aaatttggtt
    14041 tattacttac tttttcttat tctctagtaa gctaatattg aaaaaaatgt aatcagatca
    14101 ttatttttat atgttgtaac ttcctgataa gaaaactaat taaaagaaag aggtaactac
    14161 ataaactaat taaaaaagct aacttcatag ttggaggata aatggaagaa acttcaatga
    14221 ttgtttctcc ttgtgttcct tcaatcgaca ctagtcctat tatcaatctc tcttttttgt
    14281 ccatttactt ttgcgactgt tccccaataa tcaaatacag gaagcgttat tttttgtcct
    14341 ttagattcat gtactgtata gactattttc gaatccatca cttgataagg catagtatgc
    14401 cattccttgc caattcttac ttcatgattc tgcaaatgtt ctttgtattg taatgcttcc
    14461 gtgggtgcat agtcataaag tcctccggga aggagtgtcg tgtaacgaat aagattttct
    14521 tgattcatta ccaagtgatc tctctgagtg acaactttat gttcatagtt tgcttttgtt
    14581 gcagcagata cagccaacag taataaaaca attgccgtta tattaactac ttttctttgc
    14641 ttagctgatg tgctcttcat gaaaacgaac gataaaatca acgagccaaa cagtacttga
    14701 aagcctaaga ttcgccaagg aaattgaatc atttgaatgg gtgtattttg taataaagac
    14761 catggaaaaa atttggtgga taagagccaa gagactaccg cactaaggta aatcactttt
    14821 tctttgcgat taaatccttt aaaaaagaag agtggacaga tcaaagaaat aataccaatg
    14881 attcctaccg taaaggttgt caggtcatta ttcatcgcac caatcaaact atccgagaca
    14941 tttaatgctt ggtgttgtaa ggtcgtttta tctggctcat taatcgattg aaccatgatt
    15001 tgtcggaaca tcggatacca aaagtatgct gttaaaagaa tcgtcattcc tactgccttt
    15061 gacaactcca caatcaaccg gatgctttct ttttttcttg tttcacttac tacaaagccg
    15121 cctaagacta gtaagccaac ggctattaca ctcataaaag tggaaagaac atgtgtataa
    15181 atgagtaagc tcatactgac tgctaatgga attgcacatg gctttttctc ataaatcagt
    15241 gcgtaagcat aatacataac tatcggtata accgtaagtg caatcgcttc agcaatagca
    15301 gaacgatgat aaatatcaat cgtacggtac ccataaaatg tatataaaca gctaaatata
    15361 aaagccgcat cgattctttt taaaaatttt agtccataat gaaacatcag catgatagta
    15421 caaacattca atagccaaac atataagata taactaacga ttaaattatt acttatccaa
    15481 taaaaaatga ctgccggaaa aaaggtcaag tagggataaa aataattcac tccgctccca
    15541 taatgattaa acgtcgtaaa attgattgga ccagaaaaaa ttgaagataa ccctttgact
    15601 ctagcaaaat ggaaggcaat atcccccgat gtagaaatag tatgaacatt tctaaaataa
    15661 ttgattgaat aaagtccagc aataattgct aggagaatgg acaatattat ttttttcttt
    15721 acttgcatta cttaattata tactcctttc atggattgct ttatctagta taacttaaat
    15781 tttaaataaa tcgttattta tttttactct cacttaaaaa agcactaaaa ttataagaga
    15841 gggaggtaat ggtctgaaca ccaagaattg ttccaacatc gaattgctta actaatgagt
    15901 tcaaagctta attatgtggc tcttatattt accgagcgtg gattgcgatc tctttagcga
    15961 aacaaacatc tttcataaaa aaaacagcca tatccgcttt cttggatatg actatttact
    16021 actactttac tatctttcat tcttcttgtc tcacttatga taaggcgctg cgtatcatga
    16081 gtgaatgata ttaggaaaac ttcataaaat aaatctttta tacatttcca cttctagatg
    16141 gtcattcatg ttagaagaat caaactattt ttttactgtc gtaataatat taaaacacta
    16201 gaacaaatca attaaattcc ataaaatata aataatagac ctagcatcat ctggtataaa
    16261 atggatgcta ggtccgttat atttactcaa aattgattct acgaatagat cttcttatca
    16321 tttctatttt agtagtcatg cgttgttgtt cttctaaagg tggtaatggt ataagtagtt
    16381 tagataaatt tgtaccattt acatttggtt gcccagttcc gtaagaaatt ttttctaata
    16441 acttccaata taatggcgag tctaagaagc agtctacgta ttctgataat aatttctcaa
    16501 ctaacctaat tcgaatcaag taagaagcaa aaacagattc ctcacttatt tccttaacca
    16561 agaaactttt tcccatagtt cctcctgtcc ttgctatcaa aatgtcattt tcttccaatc
    16621 ttaaatcaac tagtttagaa ttactaatat cacagtaagg cacactggac caatttacac
    16681 gtccctcttg tatatctgtg attctcaaaa acttaacatt gccttgtttt ttcgccgaat
    16741 ctgtatagcc atattgaatc ttagtagaaa tacttcctaa ataaacccat agtcgaacat
    16801 cgctagatga tttttcttgt cgttctttat gaacaacagt gatcatcttg agttgtccga
    16861 ctatttttta gttgcagcaa tctttttggg acgcttattt gcatgaagca acgttgctaa
    16921 gtctagtaat aaaacattgg ctaacacagg attggctttc tcgcgatacg ctgcggcgcc
    16981 actttcaaac aatactgcta gacgatcttc tacaacaacg atttgttcca aatacggtgg
    17041 aaatttgatt cgttttagga tccggctagg agagtcccgc tcggacacta agagttccga
    17101 ggtataagga ccataagaac gactggctaa gagataatgg ccataaaaag ccacaccttg
    17161 aatcttatca gatgtttttc tgctcattgt cacggttggt tggattttgt ctttgcggcg
    17221 aattgctgtt ttcatttcag ctatcgtcgg caatagatag aaagtcaact gtccttcacc
    17281 ttttagtgtg aagttgccag ataccagttg atcattgttt tgagtcaaat acgatgcttg
    17341 tggaatctct gagagatcag ttgtcagcca ataagcgatt ggctgtcccg tctcttcaga
    17401 tgtatctgct aagatatcga tcaaacgtaa agcggctact cgtccagtag cagatcctgt
    17461 gattgtcaac cataaaagtt cccgttttgt atcatatact aagcccccta catgtggccg
    17521 tttaggtaaa atcagcagtt tgatcggctg tcctgtttct ctatccagta catgaataat
    17581 agaatgatgc tgatggtcat agcagtaggc agaaataaac acaaaatctt gagaaaaagc
    17641 caacccttgc ggcgtcatcc attgacaaac ctcattttcg ccggtttccg gcaccaccat
    17701 tcttgtttct gttaatccag gaatgttata ttgttttgct tcagcctttt cccaagctgc
    17761 ttgaacaata ggataccgtt ttaacttttt ttcaatatcc tgatgtatcc gttgctgctt
    17821 ccaatgctta aactttagga catagtaaac aagaaggcca atgaccagca acactaaaat
    17881 cattattgct acccgctgtg tcattttttt gcctccttgt tctattcgat caatcgtcca
    17941 tataccgcta ttaattaccg taactacatg tttcttttac tagcgtttct ttataggatc
    18001 tttcataatc tcatttatag taacattaag aatcccttat tctactatag tcacttccac
    18061 atcaatattg cctcttgttg ctttagagta tgggcaaaat gcgtgggctt cttctgcgat
    18121 tttctctgct tggtccttct caagtcctgg caaagaaact tctaaaacga ccccgatttg
    18181 gtagccccca tcttctaatt gaaataaaga tacccgtgct ttgacttcag aatcagactc
    18241 aagattattt tcttccagca tgtgttgaac cgcgccgttg aagcaagatg cgtatccagc
    18301 cgcaaaaagt tgttccggat ttgtcccttc actatggatt cctgggcggt cgatcttcat
    18361 gtgcatactt ccgtttggtg cctcaacttc gccatcacgg cctccacgat tgatcattgc
    18421 tgtttcgtac atttttttca ttgagatcat cctttctttc gtcgttctat attaagtgta
    18481 acgagtattt tttaatctga caaaggtaat gcttgcattc ggcgacatca gttagacaac
    18541 atcgatgatc agtgatagaa gcagtttatc tatacaaaaa aagaagggtt ctatgatatt
    18601 tggtgtcctt actcgccttg agtaacaaca ccaaatatca tagaaccact taatcagctt
    18661 cacactgctt tttctacttt cgtagttgaa aaaaacttaa acaaatcatc ggcaaatagt
    18721 taaagaaaaa acttaatcgt tgaaagaagc ccaattgctt aaagaaggca aactgactaa
    18781 tcgacggaat ccgtgctaat ccgtaaagac ctgcaattag taaactaata actgttaaaa
    18841 caagataaaa atggctaagc gtaccttgac cactttgacg ataaagcaga acaagtaaca
    18901 atgggaaaag tagaaagcct gcatagccta gcccagaacc tatattatgg atccaagtcg
    18961 atagattaca agagctttca ttcgtattga tactgaataa gccagtaaaa atacaatcac
    19021 ctatcccata taaaccaact gttgcaacaa caagtattgc aagtgttttt gatgttccaa
    19081 caaataggtg atacaacgca ggcaacgaaa gaacaaaaaa aagtccagat acaactgacc
    19141 agaccaagaa agcacgtctg actggactat ctacgtcacc aaacacacta attacggtag
    19201 tcatttgatt cagtttggga taaaaaaggc caaggatata cggtgtcgat aaatcactca
    19261 tcacacctaa taataaaaaa taaaaaccat atttttgcaa aaaaatcatt ttcttcccct
    19321 actttttagt gattattcga tacatccaac aatcaaattt tttctcattt taacacatat
    19381 ttttattcta gttgtctttt gaacaatcaa taacataaag gtgagtttct tctacatttt
    19441 aaaaaatcga atggcactga agagttcagt tgtcagcatc aatctcctac tcaaaaaggc
    19501 aaaaaaacgt aagtcagatg ttgttgacat ctcacttacg catccattga ttgaaaattt
    19561 cttagtaaaa tctactagcc taaaaatttg aagacttctt ctcgatcata cagtttaaat
    19621 actttctcgc ataaaaattg agtaattagt gccgcaaaaa cagggatgac taaccaacaa
    19681 agaacaacaa gaaagccatt tagccctgca tctaaagaag ccaacggacc aacaagtccg
    19741 accacgccga aaccagcaga agcaggcgta cctgaaatag aaaatagagc gacaggaata
    19801 gctgtaatca ctgcactaac taaacaagga ataagaatca caggttttct aaatagatta
    19861 ggcatcatca tcttcatagc gcctaaagca atcgcaattg tcacacctga cttattaacc
    19921 ttccaagagt tcactactaa aacaaaagtg gttgcagcta cgcccatcgc agccgcacca
    19981 gcagaaacac catctagttg gattgccatt ccgattgcta ctgttgaaat aggagagata
    20041 atcaaaaagg caaaggaaca accaatcaag atagacatta acagcggttg taaggtagtg
    20101 aagttattaa tcaatgatcc aattgcagaa gtaattgctg ttacaaaagg gaataaataa
    20161 aaaccaagta aacctgcacc tacacctaca acaatcggtg ttaacacaat cgacactgac
    20221 ccaaaactat ttccaatcag taaaatcagc ccgacagcaa tcgatgctgt cagcatcgta
    20281 ttaataatat cgcctgtacc agcaccaacg taaacacccg tttcacccaa atcaggtgtg
    20341 aatttgacta caccagaacc aacaaaagaa gctccggcta caaccatcat tctcatcgga
    20401 tcaaatccaa attgtaaggc aatcaaacca ccaatgatca aaggtgttgc tagttgaaaa
    20461 ataactgcta actgtgcgat cgttaccgca aagggatacg cactaaaata ttttaaaatg
    20521 gcacctaata ctgcattagg aatcaatcca ataatgattc ctgttgctgt accagcgagg
    20581 actttattca gaaaaatttt cggtgatatt ttttgtgaag tttccattca atctctcctt
    20641 tattttacgt tcaaactatc ttcttttgca tggacaagct cagtcaagaa atcacaataa
    20701 ggcgtcgcaa caccatattt cttccctttt ctagaaattg cgccattgat ataatcgatt
    20761 tctgttaatc gatggttctt aatcaagtct tgatacattg aaggataatg taacccaatt
    20821 gtttccgggt caaaacaaga ttcacaatgt gcaatgactt ctgggacatc tagttcaatc
    20881 ttctctactg ctgctacttt ggcaaactca ttgacaatcg tcgccaccat tttatgagca
    20941 gtcgatgttt ttcctagctc agccatatta acgtctaaga ttgtgcatag tccgttcatt
    21001 gttccgttca cacatgcttt gcgataaata gaatagtgaa tattgtcaga aaaatgagca
    21061 tttaatcctg attcagacaa tttgtctgct aatttttttg cagctgcttc ttttccatca
    21121 cctaaatttt gtaattctac tgaaccactt ccaaataatt tgacctgacc aggaccttca
    21181 agacctgccg tccacatggt atttccaata tagatatttt ccattggtac aaatttctca
    21241 ataatatctt catgcccgat accatttaat agacataaga cctctgtatc ttttttgatt
    21301 aatgattgga tatcctgcag cattttttcc agctgcatcg ctttggtaaa tagaataatc
    21361 agatcaactt gatcttcttt ttctacttcg gattgaagaa cgattggtag ttttgcttct
    21421 acctctttac cattaaaatt tgcttgtaat ccatgttctt tgatttgttg gacatgttct
    21481 gcccagccat cgattaataa tacttcgttc ccactttggt gaagcatcaa cccaaagcga
    21541 cttcccattg cgccagcgcc tgcaattgct attttcattg attcttcctc ctttttcttt
    21601 ctattatact catttgagaa tcttttcaca acctcgtttt gttattcttc tcttatttat
    21661 catgtttata tccaccattc aagttatttt atcagcaaat caataaaaac tggaatagaa
    21721 tcccaatttc atcgtaagag aaactagact agcaataaga aaatagaaac attcatagaa
    21781 aaaatctcac tcctctgatt ataaaagagg gggcattaac ctcgtgtata ctaaaacctt
    21841 ccattcattc gatggatgat tttctttttg tgaaaaaata ttcattgtag tacgatgttg
    21901 cgcaacacag acggatggta ttgcttatta tttattaaaa tcgaacaata cacttattta
    21961 aaaacttctt tcccaga
//
LOCUS       DARBDN010000039        21928 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000039 DARBDN010000000
VERSION     DARBDN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.039"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..628)
                     /locus_tag="SCH06_001451"
     CDS             complement(<1..628)
                     /locus_tag="SCH06_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078034.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFAL"
     gene            complement(777..1490)
                     /locus_tag="SCH06_001452"
     CDS             complement(777..1490)
                     /locus_tag="SCH06_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1078035.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            1665..3089
                     /locus_tag="SCH06_001453"
     CDS             1665..3089
                     /locus_tag="SCH06_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1078036.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            3388..4095
                     /locus_tag="SCH06_001454"
     CDS             3388..4095
                     /locus_tag="SCH06_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEG1078037.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            4082..4405
                     /locus_tag="SCH06_001455"
     CDS             4082..4405
                     /locus_tag="SCH06_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEG1078038.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(4494..5531)
                     /locus_tag="SCH06_001456"
     CDS             complement(4494..5531)
                     /locus_tag="SCH06_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HEG1078039.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(5852..6835)
                     /locus_tag="SCH06_001457"
     CDS             complement(5852..6835)
                     /locus_tag="SCH06_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEG1078040.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(7250..8020)
                     /locus_tag="SCH06_001458"
     CDS             complement(7250..8020)
                     /locus_tag="SCH06_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078041.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(8013..8948)
                     /locus_tag="SCH06_001459"
     CDS             complement(8013..8948)
                     /locus_tag="SCH06_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078042.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(9264..10913)
                     /locus_tag="SCH06_001460"
     CDS             complement(9264..10913)
                     /locus_tag="SCH06_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEG1078043.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(11030..13633)
                     /locus_tag="SCH06_001461"
     CDS             complement(11030..13633)
                     /locus_tag="SCH06_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEG1078044.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(13645..14694)
                     /locus_tag="SCH06_001462"
     CDS             complement(13645..14694)
                     /locus_tag="SCH06_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEG1078045.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(14720..15034)
                     /locus_tag="SCH06_001463"
     CDS             complement(14720..15034)
                     /locus_tag="SCH06_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEG1078046.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(15050..15496)
                     /locus_tag="SCH06_001464"
     CDS             complement(15050..15496)
                     /locus_tag="SCH06_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1078047.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(15497..17419)
                     /locus_tag="SCH06_001465"
     CDS             complement(15497..17419)
                     /locus_tag="SCH06_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEG1078048.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(17631..18527)
                     /locus_tag="SCH06_001466"
     CDS             complement(17631..18527)
                     /locus_tag="SCH06_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1078049.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(18520..19200)
                     /locus_tag="SCH06_001467"
     CDS             complement(18520..19200)
                     /locus_tag="SCH06_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078050.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(19201..19983)
                     /locus_tag="SCH06_001468"
     CDS             complement(19201..19983)
                     /locus_tag="SCH06_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078051.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(19976..20893)
                     /locus_tag="SCH06_001469"
     CDS             complement(19976..20893)
                     /locus_tag="SCH06_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1078052.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(21057..21380)
                     /locus_tag="SCH06_001470"
     CDS             complement(21057..21380)
                     /locus_tag="SCH06_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078053.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
BASE COUNT         6534 a         4508 c         3626 g         7260 t
ORIGIN      
        1 ataaagcaaa cgaggtaatc gtaataatga ttgggattaa tacattaaaa gactttaaaa
       61 cagcgggagg aatatttccg gatagctgaa tctgtagttt cttattatta gaaagtttaa
      121 taaataattc tgtagccgct aatccaacaa atatacctac aaacattcct gaagctcctg
      181 tataggatat aggtatcaca cccgtcactt caacagcttt atccgcattt tcaggagtaa
      241 acatcatctg cataggtgtt aatacaacaa atgtcgaaat agcaactaat accgctgcaa
      301 tatgatttgt ataatttctg cttgcacaca tatgataaga tactgctgct acaactaata
      361 atgtagttat gcttaatgta ccattggcaa ttgaagtacc aatttgttgt aacgtggtca
      421 atgtactagt atcgacaatt tcccccatga atcctgttgg ttctaagatc actgaattaa
      481 taagtgtcac aaatcctgct aacatcataa atggcataaa tgtagcaaac gcatctcgca
      541 aagttcttaa atggatctga ttccccaact tagtcgcaac tataccaaat ttttcaaata
      601 caatgtcctt cctgctactt ttgcccatat tttttctcct ttatgcttat tgtaatcgat
      661 tactttttcc acccaaataa tacatcactt atcaaaaaaa gtaaatactt ttaattaaat
      721 atatatatct tttttagtat aaaaaaataa gctctgaaaa aataattttc ccgagcttat
      781 ttttcaacaa aaacagcttc aaaaacaaag tcttgatata aatgtctcga taccgaatac
      841 tcgaaaggtt taccagacga tagagcaaca actttgtcta tctcaatcat aaattcacct
      901 ggatctattt ttaatatttt tgcgtcaaat tcattcgcag tatctccttt gatacgtatg
      961 tgcgaagtct ttatttccag acccagttca tttgtgatat aagcatatac agatttcttt
     1021 aaatgttttg gttccaagcc tggtatgact gctaatggca tgaatgtttg ctcaatcgag
     1081 tatggttgac aatcaataaa acggcttcgt acaatattat atacatagtc ttttacactg
     1141 atacttaatt tatcagctac ttttttcgat ggaagttcaa ttgagaaagt atggatttct
     1201 gaatctacgt gttcttcacc aaccacgcta aacaaacctt cgtttggacc aagaactcgt
     1261 gagttatcaa ttggtgttct gacgacttca gtcccatacc cacttctact tcgcaaaact
     1321 ccttcggaaa caagtaagtc tacgcctttc tttactgtta acttgcttgt atgataaata
     1381 actgccaatt catctcctgt aggaagtttc tcaccaattt tatactctcc atttacaatt
     1441 tttttcttta tatctaagta aatttccata tacttcgcaa tttttttcaa tggtgaccct
     1501 ccaatcaaaa acatatcttc atctatactt taacataaat aaaccgataa aatccacatc
     1561 aaaattatac acacaataaa aaagatatat atatttaaac aaaactattt actttaagtt
     1621 gtaagcggtg ttatcattaa gtggaaacag gaggtaaaaa aattatgaca actatgaaaa
     1681 agctaacttt tccagatgat ttttggtggg gttccgcttg gtcagctgag caagcagaag
     1741 gaaaaggaga aacaggaaaa gcagagacta tctgggatcg ctggtttaaa gaacaacctt
     1801 accggtttta tcaacgaatc gattcctcta ttacaaccga tcacatccat caatataaag
     1861 aagatataga actaatgaaa aaaactgggc ataactcctt tcgcgtttct atttcttggg
     1921 cacgaatgtt tccaaatggc ggtaccggaa aagtaaatcc caaagccatt tctttctatc
     1981 gaaaattatt ttccgaaatg aataataacg gaatcaaagt atttgccaac ttatatcatt
     2041 ttgacatgcc tgctactctt caagataaag gaggatggga atcacgtgaa gtagttgatg
     2101 cttatgttca ttacgctgaa acttgtttta aagaatttgg tgacttagtt tgtcattggt
     2161 ttaccttcaa tgaaccactt gggcctattt taggtactta tcttgaagat tttcattatc
     2221 caaacctcat tgactttaaa cgcggagcgc aagcagcatt cttcactata cttgcacacg
     2281 caaaagcaat acaagtattt aaagaactag ctcttcctag taaaataggc gttattctaa
     2341 atttgagtcc tacttttcct cgtagtcaaa atcctgctga tgtgaaagca gcagaaatcg
     2401 ctgatttatt ttatacgcgg agctttttag atcctatggt taaagggaat ttttctaaaa
     2461 agcttatcct gttattacaa gaatataatc agcttcctga agattatacg aaagaagatc
     2521 ttgtatgtat ctacgaaaat accgctcaaa ttcttggact aaactattac gagccacgtc
     2581 gcgtcaaatc tcgttcttct atggtggata catctagtcc atttttacca gagtggtttt
     2641 tcgaaccaca tatcatgcct ggacgacgaa tgaacgaata ccggggatgg gaaatttacg
     2701 aaaaaggaat ttatgatttg tgcatggata tcaagaacca ttatggaaac atcgaagcat
     2761 ttatctcgga gaacggaatg ggcgttgcgg atgaagaacg tttcatggat gatacagggc
     2821 aaataattga tgattatcgg attgagtata tcaaagatca tcttgcttac ttatggaagg
     2881 caataaatga aggatgtaac attaaggggt atcatctttg gacatttatt gattgctggt
     2941 catggatcaa cgcctataaa aaccgatatg ggctggtttc actcgacctt actactcaaa
     3001 aaagaacaat taaaaaaagt ggcgaatttt acaagcaatt aagtgataca aatggattta
     3061 gatacgatgt agacttgtta gttgaataat attctaaaat tccacttgaa gtgaacacat
     3121 tagaaaacaa gaataatgag aaataccaat aacaaatact ttttcttcat acttcattta
     3181 tacttgtcag tataagagac tgtgacaaat gtagtgatcc tcagaagtta ggtctggaaa
     3241 tctaacttga gaagattttt ttaaactacg tccagtcttt tttatttgtt taaaattgaa
     3301 gttgacaagt cttcattaaa aatttagaat attcacaagt ttgacgacaa ttatgaaaat
     3361 ttatgtcgtg ctaaaggagt tttgttattg gatgaaaagt tagatataaa aactgcgatc
     3421 aaagacacgt tacctaccgt ttttggttat atcggtattg gacttgcatt tggtatcgtt
     3481 gggaaagctg ccgggtttca tccgctggtc gtcacgttga tgtccctgct gatctatgct
     3541 ggttctgccc aatttatcac ggtcagcatg cttgctagcc atagtccact gctctccatc
     3601 gttctctcga cctttctagt caattcccga atgattctga tgagtatgac gattgctcct
     3661 tatttcaaga aaaatcggct gcttcaaaat ctgctgattg gcacattgct gacagatgaa
     3721 agtttcgcac tgggaatgaa taaattgaac tatactggac aaaagttaaa ctttcgttgg
     3781 atgaatacag ctaattggat ttcttatttg acgtgggtgg gttcttctct tgttggcgca
     3841 cttttaggga attttattac tgatccgaaa aagtttggtt tggatttcgc catcgtcgct
     3901 atgtttatcg ggttacttta tcttcaagtc atttctgata gaaacacctc taaacgatta
     3961 cagttgatcc tgattggtct cactttgatt ctggtatatg tcggactgat ttttatccca
     4021 agtaacttag tgattttagt tgtaacactg attgggtgcg gattgggggt gtggatcaaa
     4081 catgccttct tttgagttta cattgctgac tattttaggt tgtactttag caacttggct
     4141 ttctaggatc ctaccatttg tcttactgaa aaaattcgat ttgccgcaac cgttgcttga
     4201 gtatttaagt tttgtcccga tcgtcattat gtctgcttta tggttcagca gtctatttac
     4261 ccaaaatatc ggacatctgc cgcagatcaa tctcgaaaat gctttggctt cagttcctac
     4321 acttttagct gctattcttt caaaaagctt attggtgatc gtcttggtag gaattctttc
     4381 cctttcgttg attcgcttat tataaataaa aaaacaagag cttatggcaa attactgtca
     4441 tgcgctcttg tttttatcaa agtcaaataa gaaaaaaatc ggcgtattct tgcttatccg
     4501 ttgaacggac cactaacaac gacttttcct aatatatgtc ctgtttctac gtctttggtt
     4561 gcttgtttca agttcttcgc attcatccca tctgaataga ccttgctcaa tgtactgcgg
     4621 ataatccctt catttgctaa agcagcaatg tgcgctaaag cttctccttg cgtttcgatt
     4681 tcatagttat agtctgtttt agcgaacata tactcccagt cgaagctgat agattggttt
     4741 ttccaaacac ctatatctaa cggctctttg atccctacga tcgttcccac atgtccaaat
     4801 ggtcggacaa ggtgtttgat ttgatcaaag tagcgggtaa tatcgaataa tacagcgaca
     4861 tactctactt gatcgattcc taattcacga aaacttttac ttaagtcgtg atgataatcg
     4921 attggatagt ctacacctgt ttttttcagc cattcaaaat tcttcggact tgcagtcgcg
     4981 tagacttcta ggccagccca atgcgctagt tgattcaaaa tcgaaccgac gcccccagct
     5041 ccgttgatca ctaagatttt tttcccgcgg ttggcatttt cttctggagt cagaccaaat
     5101 ttttcaaata acaattcata agcggtcaat gaggtcaacg gcaaggctgc ggcttcttca
     5161 tctgaaagat tttttggtgc aagagcgaca atacgttcgt caaccagttg gtattcttga
     5221 ttgcttcctg ctcttgtcgt tgtacctgcg taaaaaacgc gatcgccgac agaaaatttt
     5281 tgcacttcat cacctacagc aacaactttc ccgactccat caaaccctaa gatacgtaaa
     5341 gcatttctta tcccgttatc ttggcgaagt ttcgtatcga caggattaac agatactgcg
     5401 ttgactttta ccagaagatc ccgtgaactg ggtacaggta tctgttcttt ttcatcaata
     5461 aagctttttg gatcatcgat cgacaaccct tcataaaaac cgactacctt cattaattcc
     5521 ttttctgaca tacgaattcc tccttagctt catcaagttg gagcatccat acagttttca
     5581 tttcaatata tatagtatgc tatttgttcc acttttattc atcataatta ttctcttact
     5641 taaagtaaac tatttgcact tttttggtta aaaaagaggt tgcgacaaga cttttgtcac
     5701 aacctctttt aaacggtgtt caatcaactg accctcggta ttcgctcaaa aaacgacaaa
     5761 atatgaggag ctatttttgt ttggctgttc ttattacttg atgcaggaca gctttttcac
     5821 gacctctaat tcacggtgtt caagcaagaa atcattgttc actgaaaagc gttggatgtt
     5881 ctttttcaaa ggtgtctaag atctctcgta cttcatcagt agatttcgta ttcatcaact
     5941 gaactcgcaa gtcatttgct cctggaaatc ctttgatata gattttaaag aaacgatgta
     6001 gtcctgtgat ggaacgcggg atgatttctg aataatgatc ttgcagatct agttgcagac
     6061 gaagtagtcc gatcagttct ttttctgtat gttccctcgg ttctttttca aatgcataag
     6121 gattcttgaa aatcccccgg ccaatcatga tgccatctac gccatatttt tcggccaatt
     6181 cttctcctgt ctggcgatct gggatatctc cgttgatcgt gatcagtgtt tgcggagcga
     6241 tttggtcacg taaagcaatg attttaggga tgacttccca atgtgcatct actttactca
     6301 tctctttacg cgtacgcaaa tggacagaaa gattggctat atcttgatga agtaggtgac
     6361 tgatccattc ttccatctca gacatttccg tatagccgat acgcgtcttg acgctgacag
     6421 gcaaaccgcc agctttagcc gcttcaatca attgtgccgc tacttctggg cgaaggatca
     6481 agccactgcc ttttccacgt tctgctacat tagggactgg gcagcccatg ttgatatcga
     6541 ttccttggaa gcccatttct gccatagcaa tgctcatttc tctaaaaaat tctggcttgt
     6601 ctccccaaat atgggcaacc atcggctgtt catcttctgt aaaggtcaat cttcctcgta
     6661 cactgtcttt tccatctgga tgacagaaac tgtctgagtt tgtaaactca gtaaagaaga
     6721 catccggtgc tgctgcatgc tttacgacat ggcgaaatac aacatctgtt acatcttcca
     6781 ttggtgctaa aacaaaaaaa ggctttggca gctctttcca aaaattagta gtcatttatt
     6841 tgttactctc cattctatca agcagtgaag tcgcaatctt tctcaaaaac attgtcatta
     6901 tactaggaaa caaaaaaaga agcaaagtga acagcttaaa agatgtttct gattgagcaa
     6961 aaaaagactg tgacaaaaat cttatcacaa ttccttttcc ggaataaatg gtgttcaaaa
     7021 gcttgcatct gcggtaataa gtccaaccaa acgaaaaata ggaggagcta tttttgtttg
     7081 gctgttctta ttacttgatg cagaacagct ttttcacaac ctctccacta aacggtgttc
     7141 aatcagctga ccctcggtat tagctcaaca aacgacaaaa tatgaggaac tattttcccg
     7201 tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttttc taacttctca
     7261 atcctcttcc tttattgatc aaataccaag taacggcgta caaaacaacg atgaatagca
     7321 caagtacgat catcgatgtt gctactggca catcgattgt tccaaggaat ccgtaacgga
     7381 aaccggagat catataaacg atcggattga ctttcgaaac agcttgccaa aatggcggca
     7441 acatagagat ggcatagaaa acgccaccta gataagttaa cggctgcaag acaaatgtag
     7501 gcacgatcga tacatcgtca taagactgag caaaaatccc gttgagcagt cctgctaacg
     7561 aaaacaagat tgccgtcatc aataatgtaa tgatgaccat gaaccatgaa tacacatgaa
     7621 gtggtacaaa gaacaaggaa atgatcgtta cgagagagcc gacgagaata ctgcgaccca
     7681 ctccgccaat cacaaagccc caaatgatca catgcgtagg aacaggcgct accaagattt
     7741 cttcgatgtt tttctggaat ttttgagaga agaaggacga agaaacgttg gcatacgaac
     7801 tagtgatagc agacatcata atcaaaccag gcacgatgaa ttccatatat gaaaaaccac
     7861 ccatgtcacc gatccgacca ccgatcattt ttccgaaaat aacaaagtac aaggatgtcg
     7921 tgatcacagg cggaaccagt gtttggaccc agatacgcaa atagcggttc gtttccttga
     7981 tagctaaact ttttaatgca gtaaaataaa gattaaacat ttttctcctc cgtatgatta
     8041 ttttcttctg tgattttcaa aaacagttct tctaaacgat tcgacttatt cctcatagaa
     8101 agaactttga ttccttgtct tgtcagctga tcgaagattc cgttcacccc ttgatttcgt
     8161 tcaacttcga cagcgattgt ctgttcatct tcaaatgtac aagcgtatcc ttcaatcaca
     8221 ggtttggtct catatggcgc taaatcaaag ataaatgttt caaattgcag tttggataga
     8281 agctctttca tactagtatt ctcgatcagt tcacctgatt ggatgatccc gatgttgcga
     8341 caaagcattt cagcttcttc taaataatgc gtcgtcaaaa tgatcgttgt accattttcg
     8401 ttcaattctc ggagaaactc ccacatctcg cgtctcaatt caatatcgac tcctgctgtt
     8461 ggttcatcca agatcagcaa acgtggttca tgcatcaatg ccctagcaat catcagtctt
     8521 cgcttcattc ccccggaaag catacgtgca cggacatttc tcttttccca aagattggac
     8581 tgcttcaaat atttttcgct gcgtttcatc gcttctttgc gagagacacc gtagtagcct
     8641 gcttgattca cgacgatttg ctggaccgtt tcaaagggat tgaaattgaa ctcttgcggg
     8701 actaatccaa tctgttgctt tgctcggact agatccgtat ccagatcata accgaagaca
     8761 ttcacttttc cagatgtttt attgactaaa gaagtaatga ttccgatcgt tgtagacttc
     8821 ccagctccat ttggtcctaa tagcgcatag aaatctcctt ctttcacgga aagatcgatt
     8881 cctcgcaatg cttcgacccc acttccataa acctttttca aattatttat ttcaagcgca
     8941 tttgccattt atttcctatc tccttataga catgattctt tattgtatca tggaatacag
     9001 cagatgaaaa aacaacttgg ttccagcgaa aaatcaggtt gctgggctca ggaaaatctc
     9061 ctaatgaaag acatcaatcg gacgaagtca gacaaccttt tcagaaaaaa caaatcgaag
     9121 ataaaggatt actattcata tgtgcaacaa aaggagcgtg agacaaaagt aaagaacact
     9181 tttgtctcac gctctaaaca cgtataaacg gcggaagcaa aagccaagat ttttgatcca
     9241 ataaatactt tcgatcactt cgcctatccc aatacatgcc actgccgctt ttcatcaaat
     9301 aacgcggctt ccgtttttgc ggtttctact aaagtctctg ggtaatccaa aactttcagc
     9361 aaggcaatcg catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt
     9421 ccttttcctt ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc
     9481 tctgtcaatt cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac
     9541 cgaacgactg aagcggaaga agcaatccgt tcgatcgtat ttgtcccttt taaaatctca
     9601 tctacgaagc agtagcagcg ttctttggaa gccacttggt ccaacaaacg tttgatcgat
     9661 ttgatttctg aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa
     9721 gtcaacacat gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt
     9781 gctagaatac agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa
     9841 cccgtgacta atgtattctt ctgccagttg accggattca ctaccgcttc ttttaacaat
     9901 ggatgataga tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatg
     9961 ggcatataag tacggtaatt caatattgca gcggctactt ctaattctcc cagcaattcc
    10021 cacagcttga tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag
    10081 ataaatggca gcatgaacat gatgttgaca tattcaaaaa tcaactctgc ttcactccca
    10141 ctcttcatac gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt
    10201 ttcagctctt cttgaagtgg tgtcggcagt tttgctagct gattggcggc tgaaatcgtt
    10261 gaaaccaaat aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa
    10321 tagaccgtat tgaatactaa cccaccgatt gccaaataga ttcctagtac ttgtcctaaa
    10381 agaagcaaac ccaaacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt
    10441 ccaatctttt tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt
    10501 cctaaacgag cgaattgata ttggattttt tctctcagtt gaggattttc ctgataaaaa
    10561 gcaatcagtt tttctaactg ctgatcttca ccaaaatcaa agctgcgtaa acgttgatac
    10621 aacgcttctg aacctacact agaataggta ctgttgattc cttcgaatac ttcgaacata
    10681 tccaggtcat accaagtaag atcatcgatt tcgctatccc atgaacggaa cttcttctcc
    10741 gtgagccatg cttccttcaa gctttcttct ttatcaaatc tcggttgata aggaattttt
    10801 tcccatttgc tacgaactgt ttcctttaat ttcaaacgtg aaaaaatgtc taaagcaact
    10861 aataaaataa cagctgcaat aataattaaa acgataaatt ctctttgacc catatccctc
    10921 tccgttcctt tatttgttag ctttagtata gcactgttgc gctatttgaa aagagggtaa
    10981 aaaaacacct ttcaaaataa aaggtgtttt tttcttgtat attacatatt tatctctcat
    11041 ttatcaaaat tgacaaataa tcatagggag gaattgttgt taattcttgt ttattctcca
    11101 gtgcattgac aactgtccca agggaaagga tagcctcagg tactattttt tcttgttctg
    11161 ttggattagc taagcgaaga acaaatcctt gttcatgaaa ataagaagga taaatcgatg
    11221 atacaattaa gtcttcaggt aattcaatca atgaaaattt acgaggaaca tcaagttcat
    11281 tttgtaatgg ccaaatcttg ttatctaacc tgtgaataaa tacattcagt ttctgctttt
    11341 gataagaaat agattgttct aaccgttttt ctgcctgttt tgccactttg aactcattaa
    11401 atcttccttc ttctacatta aatccaaaag tgactttata ctcacctatc tcttgagcta
    11461 gcggtgtttc catcatgaca tgcccttcat ttgtcgtatc tcctgaagct cgcccaggtc
    11521 gccaagcaag attaggtttt ccaagttccc ctgttgttga aaataaggtt atgattaatt
    11581 gattttctat acgttcatac tcttttaaac catctgcata aaacgtaaaa taatgatcat
    11641 tttctgccac agagacactc ttatcgaata tttctaaatt aacaggtttc tctaccatag
    11701 tttctgacca attcggagga atgacatcag gggtattttc aataaatccg ttttgaattt
    11761 gtgcaattga tttttcagat ttatctaaaa cattaattgc taagcgcata cgatgcgagt
    11821 aaacagtatt atgaattttg agtgtgcctt caacgatttg actttctccc agactgaacg
    11881 atatttcata agatatttct tccatttcgg gtttttcaga taaacgatct tttaaatctt
    11941 taggaagttg agcttttccg taaacaacta atgtttcttg taaagaatct ttatatactt
    12001 tagctgtttc taattttaga gatagttctg tatctccttc taatggtgaa taatcatacg
    12061 tatcgccatc atttgctgaa tcgatcaaat gaacgaaatc aagatattgt ctatctccaa
    12121 ctatcaaatt caattgccca tctttaaaag aaagtttata tttattgtta cttatctcag
    12181 ttttgtctat ctcgattgct gtttctaatt tttcattatt tttctcaaat tcaacaacag
    12241 tgtatcctag tgctggcaca tttacattta tttttatgtc aagttcataa taagctggtt
    12301 catcaaaata ttcgaaacct gtagcaatca tccgataagc atttttccgt tctggaaaat
    12361 aaacttcttt ttcaatgata ttatagggac tacctttgaa gtgtattttc tttgaatcag
    12421 ctactacatg cacgattttc gatccactat aattctcagt cgttgtgttg aaaacaagga
    12481 cttcattcga ttttagcttt aatgcatcag ccatccgttt tacaataagg ttttcgattc
    12541 cgtcagctat ctcattagct tctttgattc gatggaaaat atcttccgca acattatctg
    12601 aaacacagcc accaatacta tcatgagcct ggttttgcaa aatctttttc cataaccgac
    12661 gaagtaggcc tttactgata tggataccat ttctttctgc aatcagcatg agcggctcaa
    12721 ctcgttttag aattttttgt tccaatttaa aattttctat tttcattttt gttcttactg
    12781 agccaataga acgatgaaca cgagagtaaa ccggctgacg aagttcacct ttatattcag
    12841 gtaattcttt tttgtttctg ataacttcta cataagaagg ataatctgaa ataatattgt
    12901 ggaatttact gtatttattc aacttctcta cgacttgatc aaaatttaaa atcattgact
    12961 tttgatctac acccgaaggt actaaaatat ctttgttttt tccttgcata tgaagcattt
    13021 caactgcttc atccaacttt tcttttgcaa attcaggaat atctttaatt gcgtctaagg
    13081 tcatcattcc agtcatataa ccaaatggaa aattcatggc ataaacaaat ttatctccca
    13141 atcctttcca gataaaataa ggagatggaa ccatcgtttc aaagtttaat cctcgccaac
    13201 acatgaaatt atcgatttct acttgatgca aaagtgtagg caaattcgca ttgaacccaa
    13261 acgtgtcagg caaataccct accatcattg gatctccata tttaaggatc gtatcactga
    13321 ttccaatcat taagtttctt aaaattgatt cagcatccac taataaggca tctgtttgtg
    13381 cataccacgg tcccacgaat agttgtcctg ttttcatcag tcgttggata accttaagct
    13441 tttgcggatt gatctccaaa tactcatcga cgattgaagt ttgtccatct aaacaaaagt
    13501 ttactttagg gttcctttcc aattcatcta gaacttcagt aaagacctga tcagacaata
    13561 cgatggcatc ttcatttgta aaataccatt ctctgtccca gtgcgtgtgt tgaattatat
    13621 gtgcatttac catatcagat tctcctactt tccttcttct actgaattta cttgttgttc
    13681 ttttttatac ttgatggatt ttagtgcatt gaccattaac gctgtaacca ctcccccaat
    13741 aacaattgat actaaatata aaggtatatt cgtaacaaaa ggaattgcca taaaggttga
    13801 aagcattgtt tcttgagtaa caccaaaaaa tccatttaga ccacatgcta ctgcagtgcc
    13861 caccacgatg cttggtatta ctcgtaaagg atctttcacg gcaaacggga tcgtcccttc
    13921 agtaatcccc acaaggccca taatcatagc tgtctttgca ttatctcgtt ccgattcatc
    13981 ataaagtttt ttgtttaaaa ttgttgctaa aaacattcca aatggcggaa tagcaattcc
    14041 taataacatg gctgtactag gtccaaagct tccgcttgaa aaagaagcaa ccccaaaagc
    14101 atatgcgatt ttattgatag gtcctcccat atcaaacgcc atcattcctc ctaaaatagc
    14161 cgacatcaaa gcagcatttg ctcctgacat gccttctagc caattagtca gtcctgttgt
    14221 cattgcttga ataggcgtag ctagtacata ccataatatg attccaacaa ctaatgtagt
    14281 aacaaaagga atcagcataa ttgattttag actaataact tgcatcggta cttttacttt
    14341 tttcaatgca ttagctaaat agccacaagc taatccagca accattcctc caataaatcc
    14401 cataccaaga ttttgacaca tcatcccagt gataaaagct ggtgctagac cgggacggtc
    14461 agcaattgaa tatgcgatat aggctgaaat catcggtacg ataaactgta atcccgtctg
    14521 accaatcatt cgcaggactc cccagaatgt atccgtctgg tcccaaacac ctgtgccacc
    14581 aaaaatgact gcaatagaag ttagtaaccc tgctgctacg acaagcggga tcatatagga
    14641 aaccccactt tggaaatgat ttagaatttc tcttccttgt ttcttgaatt ccattagtaa
    14701 ctcccccacg atatattttt tatttgttaa ttaatgcaat tgcttcatca atcgtctctt
    14761 caccatcttt tactacctct gaggtcccta ctgttaaaat cggtttaccg tcaaagcgac
    14821 ctcgttctga aacatttgta tctactgcaa atatgacaac atctgcctcg gaaacatccg
    14881 aaattgaaag tttgttttct atccccatag ccccctgtgt ttctacttta atatctaacc
    14941 ctttcttctt cgcaaacttt tctaaattag cttttgccat ataagtatgg gcaatccctg
    15001 cgatacatgc tgttactgct actatttttg tcatatgaaa ttcctccttt taaaatgata
    15061 gagcttttac caattctttt ttatttctcg aatcttttat tcttttaaca aactcgtcat
    15121 ccatcaatct tccagataat tctgctaaaa tacgtaaatg attagtacct ttatcagtgt
    15181 cttttattgc taacaaaaag acgagatcaa ctggttgatc atctaatgcg ccccattcaa
    15241 cagaccgctt taacttggct acagccactg ttgattcaat tactgctagg cttttgccat
    15301 gaggaatggc gatatttttc ccaattcctg tggtcatatg gttttctctg tcaaatacgt
    15361 ctttttgaaa ttgtttgtgg tcagacacaa acccattagt ctctaacaat ttcgataatt
    15421 tttcgactac acttttttta tcagatgcat ttaaatctat cactatatta tttatattga
    15481 ttttttcact gatcatttat aagccttctt tcaatatata aactaatttt tcaaacgacg
    15541 aactcgtttt taaatttgct aataactcat gattcgaagc gatttcattg aatgtttcat
    15601 aaattttatt caattcaggt tttacttttt cattaagtgc aaaaaagaaa acagaatgaa
    15661 caagtgtccc atcccaatca attccttctg gattaacgta gacacagatt actggctttt
    15721 ttataaaatc tacttcgata tgcggcatag caaaatcatt catcgctgtt gaagatagtt
    15781 tttctctttt gattgctccc tctagtatcc cttctttcgc gtaattttct tttaccaatt
    15841 ttttggtaat tatatttaaa acgttcactt gattatcctt tatttggtgg gtaaaaaagc
    15901 aaaatcgttt atctaataaa tttagaaaag catcttctgt ttgttcattt aactgtagat
    15961 actgttttac ttttctgaca tctgccccta acatcaaagg actaacaaca ataacaggaa
    16021 aatttgtatt ttcaatcgga atcgtgctta taacaagttc atcagtgact tttctatctt
    16081 gtagttcatt gatgcttagt acatcttcta tctcaaccat atctgcaaaa ccgttattta
    16141 ttctttgctc taataatttt gatgttccat atccgctact acaaactaat atcactttcg
    16201 ttttgtcagg tttgtaacga tccaaaagtg attgaatatg gagtgttacg taagcgattt
    16261 catcttcatt aaaatgtata cagaatctct cttcgatttc ctctaataaa tctacactta
    16321 tcataaatga ccttttaaaa gaatatttga ttttgtccgt ataagggtta tagatattta
    16381 ctcccaattt gagtctttta actgctgcat tgagatgtaa tactagatta ttgatcaatt
    16441 cttcatcagg ataaaattca tttaatttaa ttcttactaa ctcttgtagc tcaacaccca
    16501 tatctaaata ggaaagcttc gtttgatcta agtcgtgatt catagcattt ttttcaatcg
    16561 aagtaatgtg aatgtcaaca taagcttgtt catctattgg cacaataatt gaaaatgctt
    16621 tttcaatcat tttgattaaa ataagtgtat tctttgagat ttcttcttca gaattattac
    16681 tacgtgataa gaaattgctt gtttcaatcc tttctatcgc aatagcaagg tggatagcta
    16741 aagtttgaaa ttcataatct gtaaatttca attgtgtctt attcatgtat cgattaagca
    16801 attcggctac ttttttcaat atgtccttat ttaagaaatt attcgcttca ccaatgaaat
    16861 tgatattcaa gtctaagaga tctgttttac tgttagatgc tgtaaagcca ccccaataat
    16921 agttcacaac ttctgacatc aaccttcttt tacttttttc atcagctttg atgcgcacgc
    16981 catttcgatc tgaaactaag gacatcccat gcttgtttag tctttttcta acatctttca
    17041 ttgtgctttc taccgtcgac ctgctcacgt ataattcgtc agcaagattt tgaatcttta
    17101 gagaatcatt agtattcaat aatttagcaa acacataagt tagacggtcc tccggagagt
    17161 ctgcgatatt gattttatga ctggataata aatttcgaag tgtttctttt tttccaataa
    17221 gcgaaacgcc ttttttaggt tgaaccaaca tttgtacatc tggcattttt tggattattt
    17281 ctttcaaaat taaaatatct ttgctaattg ttttcgtaga tacatataat tgttctgata
    17341 attctttgta agttgtgtgc tcattttcaa tcaaaaagta tagtattttc atttgccgtt
    17401 cgctaaattc gatgcccatt atcttcacct cctgaataca gcttaagtgt acaattatta
    17461 tctctatttt catacagaag aaagttcttg attaatgtag aagtttctaa tattcttgat
    17521 tatttcaaat caataaaaaa gcctgcaata tttatatcac aggctttttt ctctattaaa
    17581 tatatataag ataatacatt tttctactag ttctcactaa tcttgtataa ttaaaccctc
    17641 cgcaacttga cggagatgga gaagatgccc ccgtctaatc tagcggtcat ctctcctccc
    17701 attccttcca ccaatttttt tgacaggtaa agcccgattc cgctagattc cgtatttgtg
    17761 cggctggtat tttcggtata aaaacgctgg aagacttttt caacagaggt ttgcgttcct
    17821 ggtttgatag gattggccac tgttaatcga atgaatggat cctcttttga aaatgtcacc
    17881 tttgcttgtc catctgcata acgcaataaa ttctgtatga tattttgcag cactcgcagc
    17941 aacatgagcg gatctgctaa tacagttgta tttatcgagt gttcagcgaa cgctacctcg
    18001 atatttttct cagaaaattg ttcataaaaa gagaaaaata cttcttccac ctctttagaa
    18061 aaagaaagcg tatggagatc catttctttt tgcttcgtct ctattcgagc aagatcataa
    18121 aactgatccg tcatactgag taatcttgca acagattgtt tgatgatcgt taaatacttc
    18181 tcccgtttct ccgtatcctc tacctgttcc agtaattgta cataaccgtt aatagcagtc
    18241 aaaggagttc tgagatcatg agaaaggccg acgatcgata gtctgatgtt ttcttccatt
    18301 tcttgaaatg cttgtccttt ttgttcattt tcatccaacc atgtattcag tgcatctact
    18361 aggtccatta gattcttttc tcgaaattcg actgaaagac gaccaccata ttcttgtcgt
    18421 tcagaaagag tggcgatttt cttagttaat ctcttgattt ccctttgcag gaagaaaata
    18481 aaacttccca taaagataac aacgagaagc aacagccatt taatcaaatc taaaccccac
    18541 tccccacacc gtatgaatat acacagcatg tgcctttgct agcttccctc gaagattgga
    18601 aatatgcata ttcactgttt tctcactatc aaaatatggt tcttgccaaa ctgtttcata
    18661 aagatttgct cgcgaaaata cttttttcgg atgttctaaa aaaagcttca gcagatcgaa
    18721 ttctcttcct gtcaaatgga cagccacacc attcacattt acatccctcg actctttgtc
    18781 cagtaagatt tccttgtaat agatgcgttg cgacagatct tttacttgga cagaagtctg
    18841 atgacgaagt tggatgccga ttcgtaacaa aagttcttcg atatcaaatg gtttcgtcac
    18901 atagtcatcc gctcctgctg ccaacaagga aactttatct ctttgatcgc tttttgctga
    18961 aagaacgatg atcggaacat tcgatgtctg tcggatttct gctaacaatg cttcacctga
    19021 aagccctgga agcatgagat ctagaaggat caaatcgaca ggatatgtgc ttaacaataa
    19081 ttttccttcc gtacctgaat aagcatcaag aagtttgtat ctctgttcaa gaacctcctc
    19141 cagtaaggaa tgaacagctt catcgtcttc gataatcaaa atagtttcca gcaggaccac
    19201 ctacttaatg tcagattttt ggaaaataaa cattcctaga gctgatgata ccacgattgt
    19261 tactagactg accagaatca ttttcggtgc ttgcgaataa gttgcttgtt gcgcaaagtc
    19321 cgtatacatg agccacgttt ccgtaaacca ctccgttaga aattccaagc ctttgatttt
    19381 tgcgaaaaca ccgggaatga aggccgttcc catgatataa agaaaagaaa gaagcaaact
    19441 gacactggta cttctagtga tgaatgtcaa agccactgga acagataatg tccctaatgt
    19501 cagcagaagc aatacaggaa atacttttag aacataattt ccatagtttt tgattccctc
    19561 aacttcacca aatccgaaag caagtgtgta agcaagcatg gctagtcccg tgatcaaaac
    19621 cacgccaagt gttgtgatca aaagcgtaac gagaagtttc gacacataat aagtcattcg
    19681 attccgtcct aaagataacg tattgcgaat cgtaccgttt tgaaattctt ccccaatata
    19741 aaagcacgca aatgctgcga aagccagaag aatccatgca gccatttttt ctaccattaa
    19801 aatccctgtt gcaccgttga tgactgtatc cgttgcttgg tttaattcat tgccgtattt
    19861 tgtatgcata taccattcgt tccaagaata aaaaagcgga agtacgacca tcagtcctag
    19921 tgagacccac attttacggc tcttccatac ttttattttt tcagcagtta atagattaaa
    19981 catgtggatt gcctccagtt aattgtaaga aataatcttc cagtttttgc ccaactaggt
    20041 gaataccatc cacaggaact tttgcttcta ccaatgcttg attgatggct gctacttggt
    20101 caattccttc aaaaagctgg ataacacggc tagattgtac aaaataatcc ctataaccaa
    20161 gagagtcgag aaccgttact gcttgttccg tcgccgaagt gtcaattttt ataaattgac
    20221 gagattcttg tgccaattct tctttcgata attctttgat caagtgtcct tcatgcaaaa
    20281 taccatagtg agtggcgatc tgtgacaatt catctagcaa gtggctagaa agcaagacgg
    20341 tgatgccccg ttcttttacc aaacgttgga tgatttctcg catttctgcc atccctgctg
    20401 gatccatccc attcgtcggt tcatccaaaa tcaaaaattc tggattcgtg atcagtgcat
    20461 ttgcaatagc taaacgctgg cgcataccta aagagaaatt ctttgctttc tttttccctg
    20521 tattttccaa tcgcatcatt ttcagcaggt cttcgatttc tctatccgac acaccgccgt
    20581 tcgctgcttg gatacgtagg ttatctcttg cagttaattc tggataaaga gcaggggttt
    20641 caatcgattg acccatacgt cgtcttgctg cctgcaaatc cgtcgttcca aataattcga
    20701 tcgaaccttc atcaatcgag atcaaaccca taatagttct cataaaggta gacttacccg
    20761 ctccattttc cccaatcaat ccatagatca ttccacgttt gatttcgatt gatactttat
    20821 ctaatgcttt ggcagcaccg tattttttgg ttataccagt tgctttcaag accgtttcat
    20881 ttccaaaatc catacttatc cttctttctt attgatgagt gaagtatagt tgacgggtat
    20941 aaagaaagca gccagaaatg tataaagaaa gtgtaaattt tccaattgaa tgtcaaaaaa
    21001 aacaatcgga caatacgtgt ctttcctatt atcaggcagt ttgttatacg cttgtatcag
    21061 tttcctgatt ctttcttttc gaccaaagtc gtttctctgt attcctcttc actgaaaatt
    21121 tttgcttctt tcagatcaag cttgagtaat tttaccagac cggttataag gataactata
    21181 gcaagactcc ctcccagaaa aattagactg tctcgcagac gtggttgcgt tgtcttccaa
    21241 tcaaagagcg caccaaacag tgctaatcca agtggactgg ccaccatggt aatcgttgtt
    21301 atcgttgaca taagtcgtcc ttgtatatgc gttggaactt ctcgctgaag ccagaccata
    21361 taaaaagcaa aagaaaacat taatccttaa aaacggactt atgaaaaata atacatgccg
    21421 tttgggattt acaattagct accaaataag aggttatgac aaaagacttt tcacaatccc
    21481 ttcttccgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatttatc
    21541 aaacatgaga agcaattttt gtaaattcct tcttatttct tgaagctgac cacttctgtc
    21601 acaacctcag aagcggataa ataatattgt ttgatgatac tttatctttt tcccgtttgt
    21661 ttatagatcg aatgatatta tagaccaaga atcctaccta ttaacatagc taaaaacaca
    21721 aaaaaggcac tttccaaatt gtggaaagtg ccagaaaagt taggattaag gtaactgcgc
    21781 tcagcattgc ttcgcccagt acgattctcg taactcgtga actcgaacga taatcgcaat
    21841 taacgttttg agaactgtga agctttacgg gctttcttaa gacctggttt tttcttcgta
    21901 tcattgaata agtttgaaaa accttgat
//
LOCUS       DARBDN010000040        21802 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000040 DARBDN010000000
VERSION     DARBDN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.040"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            24..1103
                     /locus_tag="SCH06_001471"
     CDS             24..1103
                     /locus_tag="SCH06_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1078054.1"
                     /translation="MTQTHDNTVSRKGKHLSYSERCQIAILKKEGYSNRQVAKVLGRV
                     PQTINNEIDRGTITQLKRQTQNGKVYDTYYSVYDADAGQAFYEKQRLNCGRRPKWANT
                     NAFIDWADDKMLNEKWSPDVVVGFARKHELFDCAIIPGTTALYQWIDRGIMRTKNMDL
                     LEKLSRKIKAVRPGHRPNKRVLGTSIEERPKEVETRETFGHWEIDTVVGNKTKSDAVL
                     LTLAERQTRFEVILKLNGKDTESVDQAVQQLRERAGANFDQLFKTVTSDNGSEFSGLH
                     DALQDVADVYFSHPYASWERGTSENQHKLIRRFVPKGSPISEVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFKQERLVA"
     gene            complement(1300..2001)
                     /locus_tag="SCH06_001472"
                     /pseudo
     CDS             complement(1300..2001)
                     /locus_tag="SCH06_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(2015..2939)
                     /locus_tag="SCH06_001473"
                     /pseudo
     CDS             complement(2015..2939)
                     /locus_tag="SCH06_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3056..4135
                     /locus_tag="SCH06_001474"
     CDS             3056..4135
                     /locus_tag="SCH06_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEG1078055.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            4167..4760
                     /locus_tag="SCH06_001475"
     CDS             4167..4760
                     /locus_tag="SCH06_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078056.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(4870..5097)
                     /locus_tag="SCH06_001476"
     CDS             complement(4870..5097)
                     /locus_tag="SCH06_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEG1078057.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(5200..7788)
                     /locus_tag="SCH06_001477"
     CDS             complement(5200..7788)
                     /locus_tag="SCH06_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEG1078058.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(7808..8467)
                     /locus_tag="SCH06_001478"
     CDS             complement(7808..8467)
                     /locus_tag="SCH06_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEG1078059.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(8516..9019)
                     /gene="trmL"
                     /locus_tag="SCH06_001479"
     CDS             complement(8516..9019)
                     /gene="trmL"
                     /locus_tag="SCH06_001479"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEG1078060.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(9240..10106)
                     /locus_tag="SCH06_001480"
     CDS             complement(9240..10106)
                     /locus_tag="SCH06_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1078061.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            10215..10856
                     /locus_tag="SCH06_001481"
     CDS             10215..10856
                     /locus_tag="SCH06_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEG1078062.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(10918..12279)
                     /gene="mgtE"
                     /locus_tag="SCH06_001482"
     CDS             complement(10918..12279)
                     /gene="mgtE"
                     /locus_tag="SCH06_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HEG1078063.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(12297..13196)
                     /locus_tag="SCH06_001483"
     CDS             complement(12297..13196)
                     /locus_tag="SCH06_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEG1078064.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(13198..13995)
                     /locus_tag="SCH06_001484"
     CDS             complement(13198..13995)
                     /locus_tag="SCH06_001484"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEG1078065.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(13973..14677)
                     /locus_tag="SCH06_001485"
     CDS             complement(13973..14677)
                     /locus_tag="SCH06_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEG1078066.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            14808..15383
                     /locus_tag="SCH06_001486"
     CDS             14808..15383
                     /locus_tag="SCH06_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEG1078067.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            15501..16178
                     /locus_tag="SCH06_001487"
     CDS             15501..16178
                     /locus_tag="SCH06_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEG1078068.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(16257..18065)
                     /gene="pepF"
                     /locus_tag="SCH06_001488"
     CDS             complement(16257..18065)
                     /gene="pepF"
                     /locus_tag="SCH06_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEG1078069.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(18241..19239)
                     /locus_tag="SCH06_001489"
     CDS             complement(18241..19239)
                     /locus_tag="SCH06_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEG1078070.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(19465..20118)
                     /locus_tag="SCH06_001490"
     CDS             complement(19465..20118)
                     /locus_tag="SCH06_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEG1078071.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            20552..>21802
                     /locus_tag="SCH06_001491"
     CDS             20552..>21802
                     /locus_tag="SCH06_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEG1078072.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT         6341 a         4714 c         3902 g         6845 t
ORIGIN      
        1 tcaatagaca aggatgaatt cacatgacgc aaacccatga taacacagtt tcacgcaagg
       61 gaaaacatct ttcctactca gaacgttgcc aaatcgctat cctgaaaaag gaaggctatt
      121 ccaaccgtca ggttgccaaa gtgctgggac gtgttccgca aaccataaac aatgagattg
      181 atcgcggaac catcacccag ttaaaacgcc aaacgcaaaa tggaaaagtg tatgacacct
      241 actattctgt ttatgacgct gatgcaggac aggccttcta tgaaaagcaa cgactgaact
      301 gtggcagacg ccccaaatgg gcgaacacaa atgccttcat tgattgggca gatgacaaaa
      361 tgttaaatga aaaatggtcg ccggacgtcg tggtcggatt tgccagaaaa cacgagctgt
      421 tcgattgtgc catcattcct ggcacaaccg ctctttatca atggattgac cgcggaatca
      481 tgcgaacaaa gaacatggac ttgcttgaaa aactgtcccg taaaatcaaa gcggtccgcc
      541 caggacaccg tcccaacaag cgtgttctcg ggacgtcaat tgaagaacgc cctaaagaag
      601 ttgaaacacg ggaaacgttc ggtcattggg aaatcgacac ggtagtggga aacaagacca
      661 agtcggatgc cgtgctgctg acgctggctg aacggcagac acgctttgaa gtcatcctaa
      721 agttgaacgg gaaggacacc gaatcggtgg accaagcggt tcaacagcta agagaacggg
      781 ctggcgctaa cttcgatcaa ttatttaaga ccgttacatc cgacaatggc tcggagtttt
      841 ctgggctaca cgatgctctg caagatgtag ctgacgtcta tttcagccac ccctatgctt
      901 cttgggagcg tgggacgagc gaaaaccagc acaaattaat tcgccgtttc gtccccaagg
      961 gaagcccgat tagtgaggtg agcgagaacc agattttgcg gatccagcgt tggatgaacg
     1021 attacccgcg gaaaattttg ggttatgcga caccacatga tacattcgtc caggcattca
     1081 agcaagaacg gttggtggct tgacccatta ttccttgata acgatcctca ctcgggacat
     1141 ggcttcatgt ctggaaagct ggcctggggc cagaatcgtc tgaagactat catacctcag
     1201 ttcattatca aggcctcact gatttagaat aacgaggcag ttacggtatc aaacaaatga
     1261 gttacctgta gtggctaact taaacttgaa atttacggac gtaaagcttg ctgccaaatt
     1321 agcgattgaa actaacgatt gctttctagg aatcaaggac aagcgaatac catttgacga
     1381 ttgatttgct tgctgatcct gtacattgcg gaccccccac atcgtcccgt agagaatcgc
     1441 cattccaatc agagtgaaga aataaaaact tttgaaactc atattacgac ctgcatgaac
     1501 ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg ggcgcgagat caacgttctc
     1561 cacttctgcc actttactcg aaattatacc aatacgctgt aaaaattgat ccatgacgtt
     1621 tttcatcaac gtctgactca ttcctgcttg acccacatgg agcgaaacag atgaaccatc
     1681 aatgagataa aaaccagcca aatcatctgc atttagcttt tcattcgctt ctacttccga
     1741 tagttcctgt acttcaaata atggtttatc attgacttcg acttgttcta agactgtggt
     1801 aaaattttcc gaaagcgctg tttgatccgc tttgattaca attccagtat taatcgtttc
     1861 gagattgcca ccttgatcaa tctcgccaaa ggccgccata aacatcaatc ctaaaagaat
     1921 tggaaaggcc aatgtccaaa acaacatgga tttatttcgc agcagtattt ttgtgcgata
     1981 tttataaaaa tgccaaaaca ttatttcccc tcctctagtc tctcaaatcc ttgccagtaa
     2041 tctctaaaaa gacatcattc aaggacgctt ctttggttgc tatttttccg taactgatct
     2101 tttcttcttg taagattgta agaatcggca acaatactgt atttagttca gtagttgtta
     2161 cttggagctg acctttttta taagcgattc catcagaagc tattgttcgc tgacaacacg
     2221 ttttctggga gtaatgggat gtcgatcgtc aaacgatccg ccgtccgtac catatctttt
     2281 agagattctt tggttccttt agcaatcacc tgtccttgat ccatgatcac gatctggtcg
     2341 caaagaattt ctacttcttc catgtaatgt gttgtataga caatggttgc tccttgtcga
     2401 ttcagctcct tgatactttc taaaatttta ttccgacttt gggggtctac agctactgtc
     2461 ggctcatcta aaaaaattaa ccgcggcttg tgggcaatcc cacatgcgat gttcaaccga
     2521 cgtttcaagc caccactaag ttctcctgga cgaaacgaaa catatttttc taatcccact
     2581 aattgaatca cctcttcaat caaggctttc cttttctctt tttcggaaac atataaaccg
     2641 caaaaataat cgatattttc ttgcacactt agttcgtcaa agaccgcaac gtcttgagga
     2701 acgaccccaa tcattgcctt gacagcataa ttttcaggag tcattgttgt cccgaacaat
     2761 ttaatggttc ctttgtcata atttaacaaa gaaagcatac agttgatggc agtcgatttc
     2821 ccactgccgt ttggtcctaa cagacctaag acttctcctt cttgtacttg cagatcaaaa
     2881 tgattcaatg ctacaaaatc tccatagcgt ttgactaatt tatcaatttc gataatcatc
     2941 atgaaaaact ccttccaaat ttcttgttga tctgactata ataaagtgca agaaaagaaa
     3001 ctagtgacga ttggctaaac cacacatgac atttgtcaca atgaaggagt ctgctatgca
     3061 taaatctcgg ctactcaacg aaactagctt tctactggtt atctcattgc ttttgctggt
     3121 aagtcaagga ttcgttgcta tgcaagttat ctatttattg atcgccgttt tattcactgg
     3181 tgtcagttat ttactgccta caaagccaaa ttggattttc caagttattc tatttctttt
     3241 atgtgccttt ttacctgatc ttgtcctgtt tctgccagcg acgatgcgag tgatcgcccc
     3301 tgaagaaagc caccttgatt acttgttttt gttaggtttt ttgttgattt cgacggttgg
     3361 taatcatccc cccatcaagg tcgcctttgt cgtaattttg ctgttttttt ccttttactt
     3421 acgaaaaaaa gatcaacgaa cgaccgatct tgagaaaaag tacattgtct ccaaagatac
     3481 tcattgggaa aaacaacaag agttatcgga acaaaataaa gcattggccc tgtcacaaga
     3541 aacacaatta gccttgcaaa ttgtggaaga acggaaccga attgcccgag acatccatga
     3601 caatgtcggt catctgctgt caagtgcgat tttacaaatt ggtgcgcttg aaatgatcaa
     3661 tcaagaacca aaactaaaag aaccattaga aaatttaagt gccaccgttc acactgggat
     3721 ggatcggatt cgtcaaagtg tccatgacct ccatgagaca tcgatctctt ttcaacactc
     3781 cttagagttt ctgatcgctg attttccttc ttctgttacg attgaaggaa acttgtttga
     3841 aggattgaat gaaacgcagc aaaactgctt cttaatggtc atcaaagaag ccttaaccaa
     3901 cagtatcaaa catagtcatg ccaaaaccgt tgttttacat tttcgaacgt tgccggcctt
     3961 ttatcgcttg caaatcacga atgatggcac cagcccacaa aaaaattctg ctcccggtat
     4021 tggtttgaaa acgatgcgtc aacgtgttca agaacaaaag ggacaagtcc atattttcca
     4081 agaaaaccag caatttcagt taacgatcat tttaccaagg gagggacacc aatgataaca
     4141 gtagtcatta ttgagatgat ccatttgtga cgaaatcgtt acaaaccatt ttagaaagca
     4201 cgaaagagat ccgtgtgtta ggcattggtc attgtgccaa ggatgcgcta gtcttatacg
     4261 aaacccatcg tcccgatgtt ttgctgacgg acatccgcat gcctaaacaa acgggcatcg
     4321 atgctgccaa agaaattttg gctaaatttc ccaaagccat ccttttgctt ttgacgacat
     4381 tcaaagatga agaatacatc cgcgaagcat tttccatcgg tgtcaaaggg tatttaatca
     4441 aacagaactt gcaagcgatt attccttctg tcaaatccgc ttataatgga caggccgtat
     4501 ttggtaatga aatcatcgag actttcactc aaatgatgaa gaataaaccg acgattgata
     4561 gtcatgctta tgcttctttt agtgaacgtg agcttgcaat catcaaagaa gtagctgccg
     4621 ggaaaaacaa taaagaaatt gcagatgcct tgtacttgag tgacggcact gttcgcaatt
     4681 acatcagcca attactagaa aagctagatt tacgggatcg cacgcaattg gctatctatt
     4741 tttatcagca tttgcaataa gtcttatcta acacaaaaaa acctgaatga tgctccttcg
     4801 catcattcag gtttttttca catcttctat tcaattgtcc cgcaaaccat ttcctcacga
     4861 ttgaaagaat caaggattcg cagggctgcc aggattcgtt ggattgttcg gcgtgttagg
     4921 cggaaaaata ggcgccttgt ctaacgtttt ttctagtttt gattcttcac gatcgtctcg
     4981 ttctacatca ggactttcat tcaatttgaa ttctttttcc atctcatcta actttttaaa
     5041 gtcattgcca gattcttttg ctaatttcgc taatttatct tcggtttctt tagccataaa
     5101 gtaacgcccc ccttttgatt tcagcttagc atatcacact gaaaaaacaa aagaaaacgc
     5161 taaccaacga tcatttttag ctatttctca tctttaaaat caagcatttt ttgccggtat
     5221 aaaatcgtag ggagaactgt tttccatacc aatcatcgga tctactaact ggttatcgat
     5281 cacttctgct gtaagaacga aatctttaga aacagcaggt tctacctctt ctttcttttc
     5341 ttctccaaca aatgaagaaa acagatctgg ttccactgtt tccattactt ggtttttcgt
     5401 ttcattcgtc ccactgtcat cttctacagg tagcttttct tttacaaccc gtggctcttt
     5461 tgtatagttc ccatcttcaa atggatcatt tccgaccaaa gaatcttcat aagctgctag
     5521 tttggtccgg agagtgatat tcattttatc attatccatg atccttgatt tcaacgtagt
     5581 catccggctt gctgattcat tcgctacaca agtgacatag gcttgctctt cccctaacaa
     5641 aatcaacagt tccttactgc gagtcactgc cgtgtagagc aaattacgct gaagcatccg
     5701 ctgatattga tggaccatgg gcaaaataac catcttgaat tcactgcctt gtgatttatg
     5761 gattgagcaa caataagaaa gagtgatttt attccattcg tttcttttat aagtgacctc
     5821 atttgcatca aactggataa ctaattcatc cactttatct tcagaatctt ttgccaagat
     5881 gatacccgtg atttctccca tatctccatt gaatacattc aattcgggag tattgactaa
     5941 ttggaggact ttgtctccta tccgataaac ggtgtcgttc caatgtactt ccttttttcc
     6001 aggtttccct ggattgaata tctcctgcat cattttattt aacgcatcga tccctgcagg
     6061 tccccgatac attggtgcta atacttggat atcttgtgca cggaatccct tatttttcgc
     6121 tttttccaca attttagaga tcaagggttc aatttgataa gcatcacttc ggaaatagga
     6181 acgatctttt tgattctttg tgaaatcttt tggcagacgt ccttctttga tctcatgggc
     6241 aagaggaata atactagaac catcaccttg ccgataaatc tgattgagtt ccattttggg
     6301 aatttgttcg atttccaaaa gatcatggag tacttgacca ggaccgacag agggaagctg
     6361 atctttgtct cctactaaga taacttgcat attcgtcgga atcgctttga ataatgtgtt
     6421 agccagccat gtatcgacca tagacatctc atcaacaatc aaaagtccgc cttctaattc
     6481 tttcgtactg actgaaggtg ttttttcccg tccattcagc cccagaagac gatggatcgt
     6541 actggcaggc agacctgtcg tttcgttcat tcgtttagct gctcggccag ttggtgctgc
     6601 aagtagaata ggaaaaattt cttgggtata ttttgaagga tccaattcca gtccgttcaa
     6661 ctctgcaaaa agattgacga ttccgttgat cacagtagtt ttccccgtac ctggtcctcc
     6721 tgttaaaata aatagagggg aacggattgc ttcagcgata gcttgttctt gcgaaggtcc
     6781 atactgtatg ccgaatattt tttcgatacg ccgaatattc ttctgcactt ctttttcagg
     6841 ataatggatt tcttttttac gactgagaag gcgctggatc gaattaccga tcccccattc
     6901 agaaaagtac aaactgtttt cgtaaagatt agtctcttct tgttgtatct ttccttcttc
     6961 aacaagttgg ataattacag tagcaacctg atcaggctgg atttcaattg ggcgacttgt
     7021 ttctaaaata cggatcgttt gctgaagcaa tgtctccgcc ggtacgtatg tatctcctgt
     7081 ttgaactgca tgctgaaaaa tctgatgcaa gatagctgct cgaattcttc tcggtgaatc
     7141 tgctgcaata ccgatttgtt cggctagatt atctgcacgt ttgaacccga ttccttctat
     7201 gtcttcgact agctggtacg gattttcttc gatgatatcc aaagactcgt tcttataggc
     7261 ctggtagata ctgaaagcta actgactacc gaacccgtaa cgattcagtc ccatgatcac
     7321 ttgatccatc ccgtggttta gccgaatcgt ctcagcaagc atttctcttt ttggcttcgt
     7381 caaaccggag atttgtttta ataccgaagg atcagcaatg attttttcga tagcatcttc
     7441 tcccagcaat tctacaattt tttctgctgt tttcttcccg attcctggga atttttcgct
     7501 ggaaagatac gctacgatcc catttgcagt tgttggcttt tcttgctcat atctttcgag
     7561 tttaagctgc cttccgtatt taggatgatc cactaattct ccataaaaac gataagtctc
     7621 attttcttga atatcgccga aacttccggt gactacaatc tctttttcac ggtaatcagc
     7681 tgtggtttca ctgatgtgta ccaaaagcac tttgtaaaaa ttactaggat tttgaaaaaa
     7741 aatcgcggca actgtaccaa cgaaataagg catttcttct ggctgcatcg gaagccgcct
     7801 ccttcttcta tagtaaaggt tctggtgctg tttcagttcc taaaaaatct gtttggttcc
     7861 atactttcag ttcatatggc aataatctgc aaggctcttc agtctctaaa atcgtcaaac
     7921 tactattgaa caatccaccc atttcacgca actcacttag ctcttttcct gtcatccatt
     7981 gaatggctgc agttaaagaa gctccatgtc ctacgaataa aagtgggcca tctttatgtt
     8041 gggcaaccgc atctgctaca acagtttcga tacgtgtgat tgccgattca atcgtttctc
     8101 cgtgaaaagg agaaggatca tacagatcta aatgattacg caaattcggc agattatccg
     8161 gatatttctg gtacatttca tcgatcgact gaccttctaa agtacccagc cctagttctc
     8221 ttagcttatc tgtataaaaa atctctaccg gacgagcaag ctctttgttg ataccttctg
     8281 ctgtatcacg tgctcgcttt gctgtactgg aataaattgc tttaaaagga acatatttta
     8341 cctttttccc aaatgctttg atttcttcgt aactttgtgg caaaagcgga gaatcgccat
     8401 tgctcccttg aaaacgtctt tcctgattcc attgtgtctt cccatgtcgg gtaaaatata
     8461 gttccatacg cagcaaactc ctgtctttct tttattttac tctataataa actgtctaat
     8521 ccagcttgtc attttcatag tgatgcgtca attctaaatt agggaatcct tgctggcgaa
     8581 gtgcttcata cactatcatt gcagctgtat tcgataaatt caatgagcgg acatgctcat
     8641 cattcatagg gatgcgtaaa cacttttctt cgttttcacg cataaatgtt tctggcaaac
     8701 cggttgtttc ttttccaaat aaaaagaagt gctcttctcc atcagcaaaa ttttcgtcac
     8761 tatatacttt atgggcaaat tttgagatca aatgtagttt acgattacct aaaaatgtta
     8821 aaaaagcttc taaattactg tggtaagtaa tatttacatc attccaataa tccaaccctg
     8881 cccgttttag atgtttgtca tcagttgaaa aacctagtgg ctcgattaaa tgaagcggag
     8941 tattcgtggc tgcacacgta cgggcaatat ttccagtgtt tgcagggatt aatggttcaa
     9001 ataaaacgat atgattcatc aggatcattc ctctcatatt tatgttcgtt tctattttct
     9061 gacaatttga tttttgcata aaaaaaaacg tatcaactcg gtgtcagtca ctgcgagtcg
     9121 ttacgttagt gaagctcttc tcactaactt ttatcagaac aggaacctga taaaaaccaa
     9181 tgaaaaaaca acttgttgct aatataacac cctcaacttt tttttgcaac ctctactcat
     9241 taaaaactgc tagaaaaacg ttttctctta gttcctttta ataattctat gtcaattgta
     9301 atcttcttca aaggattctt atataagtct gctttgattc gctcttctac ctgccattct
     9361 aaaggtgaca tggccaaaag atctttttga ttttcctctg gtatctcaaa ttcataggtt
     9421 acacgctgac gttcagttaa tttcattgct tcagcaaact tggctactac acgttcattg
     9481 gaataactct gtttttcagg ttgattcgga taaaaagcct gacgtagttc ctttaaataa
     9541 ttttcttgtg gcaccacctt caacacttct ccatcttctg agagtacacg ttggaattct
     9601 tggtaatgag aaggcgaaaa gatatttaaa accgcgttga atgtttgatc agcaaacggc
     9661 aaattggtca aatcagctac acaccaaaat gcttcggcag attgttctgt agctgcgtag
     9721 actccttctt ttgaaatatc aaatccaaca gcattttgaa tctttttcaa ttttgaaagt
     9781 tcattcaaga agctaccttc tccgcagcca acatctaata gcgagacttc ttcaggtaaa
     9841 tgctgcgcaa tagtctcaat aacgggctga tacatgccag attggatcat tctacgcctt
     9901 ggaacgaaca ttccttgatc gtattctgtt ttaaccgcat gggataaaaa ataaagtgtt
     9961 ccttttttgg aaaggtcaaa acggtgatta tttttgcata tcaagccatt atcagacttt
    10021 tttacttctt cttggcaaac cggacagcgg aacagctgat gattttctgc caaaaactgg
    10081 cgtcctcggt caattttttt taacatagtt ccccctcatt tctgttttat cttaccgtta
    10141 gatgctcact ttggcaactg ctaaaaatat gatacaatgc ctagaagaaa gtgaaagata
    10201 aaggagaaga ttagatgatc aaagaatttt gcgctgaaaa ctacacatct attcctctag
    10261 caattgctag aggagccgat cggatcgaat tgtgtgacaa cttagcggtc ggtggcacaa
    10321 ccccgagtac tggtgtgatc gaagaaacgt taagttatgc tggggaaaaa gatatccccg
    10381 taatgacgat tattcgtcct agagggggcg acttcgtcta taacgatatc gaattgaaaa
    10441 tcatgcatac tgatttgatt gaagcaaaga aattagggac ggatggcgta gtatttggtt
    10501 gtcttactcc ttcaggctgg ctagacgaag aggccttaga actattgatc gaaacagcag
    10561 aagggttgca gatcaccttc catatggctt ttgacagtat tcctgaagat cggcaattcg
    10621 aagcaatcga ttggctggta gaacatggtg ttgaccgtat cttgactcat ggcggtcctg
    10681 ctgacaaaac tattgtagaa aatttcccac ggcttaaaga attgattgcc tatacagatg
    10741 gccgcttaat cattttgcct ggtggtggtg tcactgcaga gaatgcagca catgtagcta
    10801 aagaattgaa cgtaagcgaa gtacacggaa ccaaaatcgt ggatcttcag ttataatctt
    10861 ataaacaaaa aaacatttgc aacaggcata atgcttattg caaatgtttt tgttttttta
    10921 cataaaatag cccataaata aagaagcaat attgaaataa atcagtacac tcgtcaaatc
    10981 gctcaaagtc gtgataaagg gaccgcttgc tactgctgga tcaaatccta gacgatccat
    11041 tagcatcggg attaaactac ctgcaagatt cgccactgtg attgcaaata gcatagccat
    11101 ccctatgaca aaccccaaga taaaattatg tttccaaaaa cctacgatta gaaaaatcgt
    11161 gatccccgta acagctcctg tgacaacgcc ggtcaagact tcagccaaaa caagtcgaac
    11221 aaatccatga tctttctcat cagaaatcgc aagtcgacga acagccacag ctagcgactg
    11281 ggttccagca ttaccggcag ttcctgtaat cagcgaaatg aagactgcta aaatactcgc
    11341 ttcacttacc aagtcttcat agtgactgat taaagaagcg gtcgacatac ccaaaaacaa
    11401 cagagtgatc agccaaggca aacgtcgaga cgctgccttt actggatttt cattaatttc
    11461 ttccacattg accccggcaa gtcctgaata atcgctagca gcttcatcat caataacgtc
    11521 gatgatatca tcgactgtga cgattcctaa caaatgatca tcataatcgg taacaggaag
    11581 agctaagaag tcataatctc taaatgtttg tgccacatct tcttggtcgt cgcctacatg
    11641 aactgaaagc actcgttcgc tcatcagatc agaaatcatt gcgtcgtcat cattcacgat
    11701 taggtcgcgc agagaaataa cccctactag ctgaccttct tgattaacga catagatgta
    11761 atagattgtt tcagctacat ctgcttcgtt cttcagcacg tacatcgcag agcgaacagt
    11821 ttgattggct acgatcgaaa caaattcagt tgtcatgatc gcgccagccg tttcatcctc
    11881 gtaatggaga agttccttga tttcactggc atcgtctgcc gacatcaaac ttaaatattt
    11941 agcaatttgc tttttatcca gcgtattaag caagtcaaca gcattatctg tatacatctc
    12001 agaaagcata tcagctgcat agctaggacg catttcatct aggtattctt tcatatgttc
    12061 gttgtcttct tcaatcacat cgaacatatc cgctaattct ttaggcgaca gataggaata
    12121 gatcagctgc ctgttctctt ctgtaagaga ttggtagaat tgcccctgct catagatatg
    12181 catctctaaa aaactgtttc tgaatgcctg aatattattt tcccttaaat cttgagtcaa
    12241 ctgggcaaat ctttcctcta attcttgatt ttcatccaaa ccaatctcac ctcgccttat
    12301 tcttcaaacc gtctcacaac tgcctccatg tctgcggcta aaggctgctt gaactccagc
    12361 aactcttctg taaatggatg gtaaaaacgc agatcataac aatgaagggc ttgtcttttt
    12421 attcccagat ccattcgccc gccatacata tcatcaccga gcagggcaca gccaattgcg
    12481 gaaaaatgaa ctcttatttg atgtgtcctt cctgtatgca gctggatatc aactaacgcg
    12541 atttctgtta gtcgcttctc tatccagtac tcagtctgtg ccgaacgtcc ttcatcagag
    12601 accattcgct tcaatagcga agaataatct cgggcgatcg gcaaatcgat atgtccatgt
    12661 gccgataaat ctgaaagcct tccactgact aaggcctgat attttttcac aaacttcttt
    12721 tcacgaagtt gcatatctaa ttttgcgtgc gcaaatccat gctttgcaaa aagcatcaaa
    12781 ccagatgtat cccgatctag tcgcgtcacc acatggatta cttggttttc gtaaccttgt
    12841 tttttataat aagcctttac acgattagcc attgtcccat ttggatggta ttgggcagga
    12901 atagacgaaa cgcctgctgg tttatttact accagaacgt gttcatcttc atacacgata
    12961 tcgatcggtg tttcatccaa aagtacggtt tcatgttctc cttcagcagg aatcacaatg
    13021 gttaccttat catccttagc tagagaaaac aagacatttt ctacttgatc attaactttg
    13081 atttgaccgc cttgaaattt tattttcgct aacagaccct ttgagatccc tttttctttt
    13141 aaaaaatatt ttacttgctg agaatgatct ttctcataat cccatgtaaa ctgcatatca
    13201 atcctcacta ataaaggcat ctttcacacg atgccaaaaa tgcatatgtc gataagaagc
    13261 aaaatggatc cgttcttctg ctattcgata ataaattgag cggatatttg cttttgcgac
    13321 attcaattga tcaaccgtta caagataatc ttctgtattt tccaatttta tttctagcca
    13381 ttcatcatgg gcaatcacga tcggagaacc caaagtacga aacactcgat tattcagtga
    13441 agcaatctct gccaactgaa aggcattgat actaggatgg atcacagcac cgccgacact
    13501 tttattatat gctgtcgaac cagtaggcgt agaaatcgtc aatccatctc ctctaaaact
    13561 ttcaaacagc tcgtttttga tgtatacatc ggctaccatc gtacgattgg cccgtttaat
    13621 cgttgattca ttcagtgcta aaaaatgctg gtccggtgtt tcatccaaat aactgatccg
    13681 aacatccagc aagggataac taacactttg ttcccggttc gttcgtaagc tgtctactag
    13741 ttcttccagc tcgtaatccc gccaatccgt gtaaaaccct aaatgacctg tatgcacgcc
    13801 caagaaacgc acatcattca gacaatgact gtagtgatgg aacgccgaca ataatgtgcc
    13861 gtctccgccg actgagatga ccaattctgg ctcatgatca tctcgttgaa tccctgcttg
    13921 ttctaaaagt gcgttcaaac gttctgtcac ttctatagtc tttgcttctt tattatgaac
    13981 gatcgctact ttcatcccct gcctcctctc tttcgctttc tttcttcaaa agcgttcgat
    14041 agtagacatc atctgatttt cctcttccat gggagaataa ccgctgtgct tcttggattt
    14101 cttcacggat actggacatc tcttcatcca actgataggc agcttctgcc gcacgctgaa
    14161 gtcgttcact catttcttct ggaaaaacgc cttgatattt ataattcagc gaatgctcaa
    14221 tcgttgccca gaaattcatc gcaagagtcc gaatctggat ttccgccaaa attttcttct
    14281 caccgctgat cagctgtaca ggatactcga tcaccagatg ataagaacgg tagccacttg
    14341 cttttttatt tgtgatgtaa tctcgttctt ggagaacttt catgtctttt cttttacgga
    14401 tgatctcaac aacttgatgg atatcttcta caaactgaca catgatcctt aacccggcaa
    14461 tatcagacat ttcttcttct aaacgtccca ttggaatatg ccgtaattgt gattttgtta
    14521 caatactatc gactggcttg actctcccag tgacaaattc aatcgggaca tgtcgatttt
    14581 gttcacggaa ctgtttgcgg atcccccgca gtttcacttt caattctgat acagtttgtt
    14641 catatggtgc taaaaatgct tcccaatctc gttccatagc tgatacctct acttcattaa
    14701 cattcattgt ttattctacc atatatgcaa agttttttcg tactcttgat ttatgcattg
    14761 accaaaaaaa gaaaattagg caaaatagac aaaaaggagt cgatcaaatg acacaaatgc
    14821 ttgaaatcga atataaatct atgctgacaa agcaagagta cgagatattc atcgctcact
    14881 atcaattaac agataaagat ttccgtgtac agactaatat ttatttcgat accgttgatg
    14941 aacagctgaa gaaacaaaat tgtggcctac ggatccgttt cgttggtcat caagctgaat
    15001 atacattaaa aacacctgct gaaaaagggc gtctcgaaac aacggatacc tttataacag
    15061 aagaagcaga agcatttatc ttcgaaaaac gtctgcctcg ttcaggcgca gtttttcaaa
    15121 aactttctga tttgaatatc gatcctgctt cattaatcca aaccggaaag cttacaacaa
    15181 aacgggctga attccctatt gaagaaggac ttttagctat tgatgaaagc tggggagaca
    15241 atctacacga ttttgaactg gaactagagg taggggatgc atctgtggga aaaattgctt
    15301 ttataaattt tttaaaacgt ttttctttac cttatcgtcc tgctaagaac aagatccaac
    15361 gtatgcttga agctaaaaat tagaaacctt tcattttcac aaggcacttg agttcatttt
    15421 tttacttttt tctgttaagt tataggatgt gaaagaatct agtcactagt tgtatagaat
    15481 ctattttggg ggagattcat atgatcgaaa tctatttatt tgttaatcct ttaggggaat
    15541 actgtttcga aatggaacaa cagttattac aatttatcga agaagagtac gggacaccat
    15601 caaaagaaaa gatgcaattt cgctttcttc ctttggtcaa tttgcagaca attggggatg
    15661 tcatgcaaca aaaaggaatt tctcagaaca atcttgagga acgtaatcac ttattctcaa
    15721 tgacttattc tgcagcattg gactgcaaag cggcgcagtt tcaaggaaag aaaaaaggcc
    15781 gccgtttttt gatcaaattg caagaagcag tcggctgtaa tgacatacca tattctcaag
    15841 aacttgctga atccatattt gaagaaatcg gcggcgattt gaatatgttt aaagaagatc
    15901 gtcagtctga cttcgttaaa gaagtattct tttctgatca aaaaattgct cgggaaatgg
    15961 gcatcacaaa acacccttct gcagtcgttt acaattatgc ctgcgaccgt gattttggtg
    16021 ttttagtaga agtaaaaggt acaagtagcc tttggagaat cacagagctg tgtaaaacaa
    16081 cagataactc atatcaagtt tttaatggtg aacatttaca tacaaatgat tctcagttcc
    16141 attcaagaac tagccattta cacttgcttt ctaattaaaa aaatacgtcg actcccttac
    16201 aagagagccg acgtattttt ttcgtttcta ttcgagaaaa tcaaaaatag aaagccttat
    16261 aaacgatcga tcaattcttc taattcattt agacgttgtt caaacatcga cattgcatct
    16321 tcaatatatg cagcctgtgt catatcaact cctgcttttt tcattacttc cacaggataa
    16381 tcgctgttac ctgcttttag gtaagccaag tagttctcta gtgcctctgg ttcctggttt
    16441 agtattttct tcgccagtgc tgaagcagca gaaaagccag tcgagtattg gaaaacatag
    16501 taattataat aaaaatgcgg tatccgtgac cattcgaatt taatttctgg gtcttcttcg
    16561 actgctggac cataatattt tgcattcaat ttaccataac tatcacttag gtattcacta
    16621 gtcaatggca cacctttttc atcttccgta tgcatgaaat gctcgaattc agcgaattgt
    16681 gtctggcgga aaactgttcc tttaaaccca tccaagtaat ggttgagtac ataagcccgt
    16741 acacgagggt ctttttctgt ttccaataaa tactccgtta ggatattttc attcgttgtc
    16801 gaagcaattt ctgctaaaaa gatggagtag tcgccgtaca cataaggctg gttcgaacga
    16861 gtgaaataac tatgaacact atgtcccatt tcgtggacaa gcgtaaatag ctgatccagc
    16921 gtatcatgcc aattcaataa aatatatgga tttgtgtcat agcttcccga agaataagca
    16981 ccgcttcgtt tccctttatt ttcgacaaca tcgatccaac gttcagagaa tgctttttct
    17041 acgatggcca tgtattcttc acccattggt ttcagtgctt ctaaagcttt ttcttttgct
    17101 tcttcgtacg taaaggtaat tggagcttcc cctaagaccg gtgtataaag atcatacatg
    17161 tgcagttttt ccacttctaa taaacgtttc cgtaattcca tgtatcgatg taacaaaggc
    17221 aaatgcttgt ttaccacgtc taccaaagta tcgtatacac tttcaggaat atgattattg
    17281 ctcaaagacg cttctctggc agagctgtaa ttacggactt tcgctttaaa attatgtcct
    17341 tttatatgtg tgcctaaagt agaagcaaat gtatttctaa attgttcgta aacactgtac
    17401 aatcccttaa atgctgcttc gcgcaccctt cgatccgtgc tttctagcaa ctgaccatac
    17461 acgccatgag ataattggac tatttcacca ttttctcctt caatcgttgg aaaaactaga
    17521 tctgcattat tcaaaacagc aaatgtatca cttgaagcat caaagatttc acctgctcca
    17581 gcaagaagag attcctgctc agcagataag acatgggctc gattatctac tatttgctgg
    17641 atataatggc gatagacttc caattttggt tcttctttga aatattgcca aatctggtca
    17701 tctgacaatt gcaatatttc tggttcaaac caggaaacgg cttcactaac tttcgaaaac
    17761 agactgcttg ctcttgcata aagcgcttgg taatctgtat ttccagtgtc ttgatcgttt
    17821 ttaaggtgcg catatacata aatgacttca gtttggcgat aaaccctcaa tacgaattca
    17881 atcgcattta aaaattgaga agcgccttga tcaagtgttc ctttgtgttt ttcagattgt
    17941 tttaactctt ctgataattc caaatatttc tcatcaaact cttggtcgct tgaaaagatc
    18001 ttggtcaagt cccaagttaa attttcaggc aattcttctc gttttggcaa ctgctttact
    18061 tccatgaaat ccactccttt tcttccctta gctctatcta tcaaaataga tcatagtcta
    18121 acatccacat gtcacagcat ctaacttttc tactcattca tgtgtctgct tccatcaatt
    18181 ttagcataac taaatcttgt tttacataga aaaccgattc ctagcctatt tttatactta
    18241 ctattttttc aaagaagaca agtgtatgca ttcgttaaaa aactgctgat agaccatctc
    18301 ttcatcaatc ataggaaaaa gccattccct tttatgttct tttatttggc aaagccatga
    18361 gttgaaatca ggaactttct ggttttccaa ggcttcttcg tacaacattc gataaagaaa
    18421 aacctgttct tgtaaataaa agaaaaaccg acttttttga tagatccacg atgatagatg
    18481 caaaagatgt ttatgacgca agtagcattg ttcttgtatg gatactgtat tcttttgctt
    18541 gtgaataagt tggcgtgtca gccatttctt cccatcttca ctcacttttt ctattttttt
    18601 catttggttc attttaattt cgttactagt gaatatttct ttaaggtccc tactagaaaa
    18661 agtccagcag ctactgcaaa aggaaatatg ccctgataca gtctctgtaa tatgatgata
    18721 caaataaagc ttttgtttct tgagatcagc tttccagcaa tgcactcctc tttttctatt
    18781 atagtagcag caactttttt ctatcaatga gaattgcgat tgtccaagaa aagaattacc
    18841 aagtatccac catacttggt aactgttatt caaataattt tgggttcttt caataaatct
    18901 ctggtgagac agtctagaac attggatttc tattgctaga ttcgccaaca aaatatccgg
    18961 cctttgccgc aacctcggca aataggcttc caaaaatact ggttctactg actgtcccag
    19021 ccaatccatg aagcattcct ttaactgtaa gtgctctttt gattctcttt cactaaagac
    19081 cgaacagtta tctgattttt gatgggcaaa atgagcacat tttttctttc cctttttcaa
    19141 aatcactctt tttcgacagc cacgacaata atatttcttt cctttttctg catgtttagc
    19201 aaaacagcac ttattatatt cattcattgc aagcagcatt tttctccctc tgaacttatt
    19261 tacgtctaag aatttattta cacgaaaaaa gagggcgtga aaaagctatt ctgcatcaag
    19321 taataagaac agctaaacaa aaatagttcc caatattttt cgtttggttg ggcttgttac
    19381 cgcagatgca agcttttgaa cacatttata cgaaaaaaag actgcgacac aatttttgtc
    19441 acagtctctt actataatgc tgatttatac aaaataaaat ttcgttcgct cgatagcatt
    19501 acgcgccatc agacattgtc catattcatt caatgtttct ggtgtacgat cgctcttttc
    19561 agcaaactcc aaaattcgag caatctgatt ctctacatcc gcttggttga gattttccat
    19621 ccagaagtga acgactaggt aatagcgctc ttcgaataaa tacaaatcag tccaagcaga
    19681 ctctagttcg acatctgttg caagttggat cacttgttca aaatcttcaa aagcaaaagt
    19741 tgcttgtctt tcctgttctt ctagggcgct tccagataat tcttcctccg gatcgctgcc
    19801 aataatctgc tgacgaagaa agtcactcac atcttctgaa tcaacagtag aatcttctga
    19861 ttgagaaatt tcttcatccg gaagattttt actgataaac agttctaatc cgtctccttt
    19921 tggcaaaact tggaaagtga cagcttcgct tcctcggaac tcctcttcga tatcaacttc
    19981 ttccaaaata ctataaaaga aattttcgat ttctttgtga ttgccaagta aatccaaaaa
    20041 tgaaacgccc cgttcctcta aatcttcatg accaattagt acacggatcg tattttcatt
    20101 aatatgttcc atttccattt tgctacacct cactttgcca caatgtttaa tatagattca
    20161 ttgtagcgaa atcagcttaa atgtaaagaa aaaaaatctc gctgttaagc gaatttaata
    20221 aaaccagcgg atttttcaac ctttcaagct atcttattta actataacat ttttggcaga
    20281 cgaatactat atagccgact tttcagctaa ttttccctct ctatttttcg tgcaatcatc
    20341 atcttctact acctttttat acatctaatc aagaatactt tttgtaaaaa caaaaaaact
    20401 tggaaaaact atctttgtaa tagtcttttg gctctatact ttttgatgtt ggtgaacttc
    20461 accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta
    20521 atttggctac caattcatag gaggattcaa gatgtctcat actcagctta tcaaagatac
    20581 cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta aagaaaaata
    20641 caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag aagagtgttc
    20701 ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa ccgttcggtt
    20761 gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac aacgatttaa
    20821 atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa aacactgttt
    20881 cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata cttccatgac
    20941 ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca tgaagcgatt
    21001 ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct ttgatgaatt
    21061 caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg gacaaagcca
    21121 tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct atttttctcg
    21181 gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt atgcgcctta
    21241 tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc gtttccacat
    21301 cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca cggtacgact
    21361 taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct attggaaact
    21421 cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg ccagttttaa
    21481 agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc ccaacttacg
    21541 ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag atcagtcact
    21601 atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata caaccacttt
    21661 acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca gctattcaaa
    21721 cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg cgtacggctt
    21781 tcgcaacttt tacaatttca aa
//
LOCUS       DARBDN010000041        21618 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000041 DARBDN010000000
VERSION     DARBDN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.041"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(205..1104)
                     /locus_tag="SCH06_001492"
     CDS             complement(205..1104)
                     /locus_tag="SCH06_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEG1078073.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1114..1470)
                     /locus_tag="SCH06_001493"
     CDS             complement(1114..1470)
                     /locus_tag="SCH06_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEG1078074.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1825..2121
                     /locus_tag="SCH06_001494"
     CDS             1825..2121
                     /locus_tag="SCH06_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HEG1078075.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2644..3597)
                     /locus_tag="SCH06_001495"
     CDS             complement(2644..3597)
                     /locus_tag="SCH06_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1078076.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3620..4375)
                     /locus_tag="SCH06_001496"
     CDS             complement(3620..4375)
                     /locus_tag="SCH06_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1078077.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4372..5331)
                     /locus_tag="SCH06_001497"
     CDS             complement(4372..5331)
                     /locus_tag="SCH06_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEG1078078.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5324..6274)
                     /locus_tag="SCH06_001498"
     CDS             complement(5324..6274)
                     /locus_tag="SCH06_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEG1078079.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6424..6876
                     /locus_tag="SCH06_001499"
     CDS             6424..6876
                     /locus_tag="SCH06_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEG1078080.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(6965..9232)
                     /gene="gshAB"
                     /locus_tag="SCH06_001500"
     CDS             complement(6965..9232)
                     /gene="gshAB"
                     /locus_tag="SCH06_001500"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HEG1078081.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9419..10417)
                     /gene="ftsY"
                     /locus_tag="SCH06_001501"
     CDS             complement(9419..10417)
                     /gene="ftsY"
                     /locus_tag="SCH06_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEG1078082.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10428..11237)
                     /locus_tag="SCH06_001502"
     CDS             complement(10428..11237)
                     /locus_tag="SCH06_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078083.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11246..14827)
                     /gene="smc"
                     /locus_tag="SCH06_001503"
     CDS             complement(11246..14827)
                     /gene="smc"
                     /locus_tag="SCH06_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEG1078084.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14847..15533)
                     /locus_tag="SCH06_001504"
     CDS             complement(14847..15533)
                     /locus_tag="SCH06_001504"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEG1078085.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(15881..17662)
                     /locus_tag="SCH06_001505"
     CDS             complement(15881..17662)
                     /locus_tag="SCH06_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1078086.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17688..18602)
                     /locus_tag="SCH06_001506"
     CDS             complement(17688..18602)
                     /locus_tag="SCH06_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078087.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18629..19591)
                     /locus_tag="SCH06_001507"
     CDS             complement(18629..19591)
                     /locus_tag="SCH06_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078088.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19591..20535)
                     /locus_tag="SCH06_001508"
     CDS             complement(19591..20535)
                     /locus_tag="SCH06_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078089.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20536..21540)
                     /locus_tag="SCH06_001509"
     CDS             complement(20536..21540)
                     /locus_tag="SCH06_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078090.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
BASE COUNT         6037 a         4620 c         3817 g         7144 t
ORIGIN      
        1 tatatttttt tttgtgatta tcgttcaaaa aaagaataca cgcttgcatc tagtactctg
       61 cgagttacaa atcatccgat caaataaaca ttcgctgatt attttccgca aaaaaagcag
      121 catatccacg ataaatggat ctactgctct tacttatcct tatgttttac aaggtatttt
      181 cttttacaca ttactaatgc tgtctcaata cggaacgatt gtcatcgctt gttcaaattc
      241 ctcttgcaaa tgttgtgttt gataggcctg aaaagctggg tgatgggcac gcaagaggac
      301 acgtaatttc ataggatcat agctgtctag caactgttct ttcaagacaa aatctcgggt
      361 cagctgccat tcataataat aaccaaaagg tctgcagctg taaatcgtgt gaccgatgga
      421 tttatcttca aagcgacgat gcgtatggcc aaaaactact tgtttgatat ttgaataacg
      481 gtcaagtaat tctccgaatg attctgatcc taaaaatgca tttaatttgt tccaacgctc
      541 ataaggagca gattgataca tgataaatgc ccgtttagga acgaaatgag tggataaaat
      601 cacctcaagt ttttttgctt ccagctggtc tagcaaattt tttgcagctg caagcatttc
      661 tgcattgacc tcgagatctg ttttcccacg ctggatgaac cgatcatacc aatacaaacg
      721 cttcattcgt acgattgcct cgtaatcttt caattcggaa aactgatagt cgtaccagcc
      781 attcatccct aaaagaacgg tctgctcatt taaagcaata taccgttcat ttaaaaaatg
      841 tgggtctgga aaatggtcca tcatctgttc attgggcaca tctgccaact cgtgattgcc
      901 gaaatgaaat gtcgtagata atcctttatt gacgaaaaat tcgacaacag ctaggcaacg
      961 gtctacttta ttagccgtat ctccggctag atgaagccga gtgatcttgt gcttttgcaa
     1021 aacttgccaa agctgcatca gctctgattc gccgaattta ttgatgtcca catgtaggtc
     1081 gctgatgatc gccaattttc ccattttatc cctctagtct tttcgaacaa cttgcaagtt
     1141 gccttttctc aagccgcttg gtccttttaa ttgtaaacta ttataagttg gttctaaagc
     1201 aagtgtggat ggatcatcca tgtaaagtat tgcactgtct ttgattttga ttggtccaac
     1261 tggtgtatca gccactacag aataaagact tagatctgtt tgtgtatctt ttttgacaat
     1321 gatcaatcga aatgccgtat ccaattggca actgacttgg ctttctgcaa atggaccgtc
     1381 accgttttcg atatctaata aaagttgatc gtctgcttct aatttattct tcaatacttc
     1441 ttgtgcttct tttgtcactt ctaatttcat ctgtatcacc tcatgtcata gaataatcac
     1501 tttattcatc agatgcaact aatttgtctg gttctgactg ttctcaattt attggaaagt
     1561 aagtcattcg tttattatga tttctcttat cacaaaagag acaactttcc cttttcttcg
     1621 ttcagtttct tgaacggaaa aagacccaaa aagcaacctg ttatttgttt aaccttattc
     1681 ctttcttaaa taacaaaaaa tactataaaa aataaaaaac ctttaacaac tattggaaaa
     1741 agaattactt tttgttcacg gattattaac aactcttcgg tagagtaaac ttatcaaata
     1801 aaagacttct ttggaggaat cactatgaag gaatatataa aaaacatcta ttttatcgaa
     1861 gaaacacaaa atatcgaggg ttcttatatt gaagtaaaaa cactctttgt caatgaagat
     1921 aaaaccaaag cattggatat ttataaaaaa ttagcttcaa aaaaaacgaa tagttttgga
     1981 ttgatattaa gcgagtataa aatcaaagca gaagagagtt atttctatca attattaaaa
     2041 cggtggagta agcttcccgc cgatttttat cgaaaaatgc agatcatcaa ctatcaaccg
     2101 cttgctgaga cacatgccta aatagaggtt gtgaaatcag tgctttgagc taataccgaa
     2161 ggtcagctga ttgaacattg tttagaagag attgtgacaa ctgcgatttg ctttgagtaa
     2221 taagaacgct ggacagaaaa tagcttctca tattttctag tctagtggac ttattgccga
     2281 gaagcagcag atggaacatc gtttaaagaa gagatcggta caaaataaaa atatctaaat
     2341 ttaagtttta tctaagtttc gctttgtacc tttgattcaa atcaaaggag gcgatcttga
     2401 tgctgaaaaa atggatcaca ctattttttg ccactcccca ttctagaatc aacccgtatg
     2461 atgtagataa tgaattcacg ttgaaaaaag atttctcaaa taaataaaaa ccatccgtaa
     2521 aatcatcaat acgattttac ggatggtttt tgataacttc tttgaggata ggctcttgct
     2581 atttaagaat gtaagaaaca ttattgttac atagtatgag agtttaatcc tctgttattt
     2641 atgctattta aatgcttgat tcacatcttc gatcatcagt ttcattgatt ctaaaccgcc
     2701 cccgcttaaa taccagacat ctggttcaag ggagatgatc tgctgatttt taccagcatt
     2761 cgtttgtgct accagttcat tggcagaaat atcatctttg ctgtcgtctc caccaatagc
     2821 ttttgttctg tctactacaa ataagatatc cggatttttt tccagcacat attcataaga
     2881 aacactttga ccgtgagtgg atgcttcgat ttgatcatct gcttgttcaa agccaaataa
     2941 atcatggatg aaaccgaatc tagaaccaga tccgtaggct gataattgcc cttcattcac
     3001 aagtgtgact agtgcttttt tgtcagtagc ttctgctttc tttttcgtct gatcgattgc
     3061 actagataat tcctctaatt gagttttagc ttcttcttgc ttaccaaaga tctcccctaa
     3121 agcagtgaca ttttgctgga aagattccca tggatttttc gcatctaaag aaaggaaaat
     3181 ggtcggagca atttgactta gatctttttg aaaatctctt tgtcggccag aaatgatgat
     3241 tagatctggc tgaagctgat taattttttc taagtctggt tcttttattc cacctgctga
     3301 ttctactttt ttataggatg aaagatactc aggaaggctg cttgtagctg ctccaactac
     3361 cttatctcca acaccaagag catccatcgt atctaaagaa ccattgtcga atacgacgac
     3421 tttttctgga ttatttggca cctcgatttg gtctccatta ctatctgtta tcgtcaatgt
     3481 agtttcagtt tgtgtgctgc ttttttttgt gtctgcctga ctggtgttgt tgctatttcc
     3541 acatgctgct aaaccaaatg atgctagaat caagatacct actactaatt ttttcatctc
     3601 ttctctccta atgttagttt tagaaataaa gacagaatct gcggccttca atctcacaaa
     3661 tccgtatgtc catttcgtat aattcatcca atacatcttt ttttatcatt tcttgggtcg
     3721 ttccttgcgt aaataactgt ccatctttca ttgcaacaat ttcgtctgca taacttgcag
     3781 caaagttgat atcatgaaga acaataacaa ttgttttccc gatttcttgt actaaatttt
     3841 ttaaaatctg catgatttga accgcaaaat tcatatctag attgttcaaa ggttcatcca
     3901 gtaaaatata atccgtgtct tgcgctagca ccattgcaat atacgcacgt tggagttgac
     3961 cgcctgaaag agtgtcaatc gattgatccg ctatttcttc taacccaagg tgttccagtg
     4021 attcctgaac gatttcctcg tcttttgtcg tcaattttcc tttcgtataa ggaaatcgtc
     4081 caaattctac taattctttc acggtgattt ggacatttat ttcattcgat tgtcgtagga
     4141 tcgataattt tttggctaat tcattggatt tccaagcctt tacttcgtta tggtctaaat
     4201 agatttcacc tgtatctttt ggtatcaaac gactgatcat cgacaacacc gttgactttc
     4261 cagcaccatt tggaccgata aaagcagtca atttcttttc aggaatcgtt aactgtacat
     4321 ctttaaccac tgattttcca tggtacagtt tattgacctt ttgtaaatca atcataggat
     4381 actcttcctt tcgcgaatca attttgtgac aaaataaatt cctccgacaa attcaacgac
     4441 gacactcact gttgtattcc agccgaaaat ctgctctact gcgagctgtc ctcctgtcag
     4501 aaacagcata gctaccagaa agcttccgat aaatagctga ccatgacgat aagtagaaaa
     4561 gacacgataa ctgatatttg cgacaataaa ccctaaaaaa gtaactggac ccacaagagc
     4621 cgttgatgtc cctgtcaaaa gactgacaca acataaaatc aaaaattcaa aacgatctgt
     4681 gtctatcccg aggtttactg cttgttcatt tccgagatgg aaaacgtcta gcacatgtcg
     4741 atatcgaaat aacaggtacc agcagccgat aatgatcaaa gaagcaggca aaagatactg
     4801 actctggata ttgccaaagc ttgcaaataa tctgccttga agcaaatcat attcattcgg
     4861 atccatgatg acttgtaaaa aggtactgac actaccaaaa agcgtaccta aaatcatccc
     4921 tgacatcagt aataaaaaaa gattcgctct catttttttc aaaagaaaga aaaataacaa
     4981 tagactcagc ccgaccatca gcccaacgtt caataagaaa aaaactgtac ctgtctgctg
     5041 aagcatcgtc actcctccga taaagaagaa aaggaccgtt tggacaagga catataacga
     5101 ctcaagtccc aatactgaag gagtcaaaaa ctggttatgc gtaattgtct gaaagctgat
     5161 tgtggcactg ctgacagcta gcgagacaag gataaatgca aaaattttct tactcctcaa
     5221 tgcacatgca aaatgccagt ttccatatgt atggatcgtc aagtacattc ctgtaacaaa
     5281 taaaacaaga acaagcatac caataaaaat agatggcttt tttttaagca tatcgtcgtc
     5341 cccttatcag aagataaagg aagatagccc caccgatgat tccaacgatc acactgactg
     5401 gtatttcata aggaaaaatc aacacgcgag cgacaagatc gcaaaatact aagaacaaac
     5461 tacctgctaa agcagttacg ccaattgttt tgtgcacttg atctccatat attctagaga
     5521 caagattcgg aatgatcact ccgataaaag gaatgcttcc taccatgatc aacatgactg
     5581 cactagccaa tgatactaag ccaatgccta aaaactgcat cttctggtaa tctattccca
     5641 gatttactgc aaacgattcg cccagaccaa tgatcgtaaa tcggtaagca aatagccaaa
     5701 ccaagagcaa caatggaaca acagcataca ataactcata atttcctcgt atcacagtcg
     5761 caaaattccc ttgaagccat gaagtcatat tttgtaccaa ctggaattga taagcaaaaa
     5821 aagtagcaac tgaaccaatg atattcccta acatgactcc aatcaacgga agcatcaatt
     5881 gatttttctg gaggaacaat cgcgtaaggg ataaaaaaag caatgttcct gcaaaagcaa
     5941 agcaaaatgc tgtcaaggat cggacaatca aggatgcacc aggtaggaaa atcatagcca
     6001 ctaaaatacc taaacgcgca ctatccatcg tgcccgcagt cgttggtgaa acaaatttat
     6061 tttgggtcaa atgttgcatg atcaacccac aaatactact ggtcgctccc acaaggatca
     6121 aacaaatcgt tcgtggcaaa cgagtcacta gcaagatttg taagctttgc ccatctaact
     6181 ggagcagttc tgacaattgt acattcgata ctccgatgaa caatgaaata ctacttaaaa
     6241 taactaataa tgctactagt cgtccgtagc gcatccaatc cacctttcta attgagaatg
     6301 attttcattc ttattttaag tgaatcgttg aacaaaagca accgcttttt catatgtttt
     6361 aggtattatt gggaatatgc tataatcgta agaaagacaa agagaagaag gagggtattt
     6421 tttatggcac aagatgatgt aaaaagccat ttggataagg gactttatgg tacaccttta
     6481 gtgaaccctg aagaacagca taaatattta gggacattca gggaacgctg ctatcttagt
     6541 atgactgttg ctgaaatgat ccaaccaaaa aacaaagaaa actttttaaa agaactcaaa
     6601 aaacatccag atgcttccat actcttgaat ggggctctac ccctttctgt ccaaaaccaa
     6661 tatatccagc tagcaacgaa aaacaatagc cgtttcactg tagtcaacga ttacgtcact
     6721 gcaaatcctg aggaattcgg attgctctta acagcaaaag aagcagtaaa tgaacctgtg
     6781 attgatatcg aaaaaaaata cccagaagaa aactcttcgc cagctgaaaa agaaaaacca
     6841 aaaaagaaaa aaagcttctg ggatcgttta ttttaaaacg aaaaaacaca taaattttta
     6901 catgcaaaaa aagcttttga tcagattgac atcaaatagg acaatctgtc aaaagctttt
     6961 tcttttaaaa tacttcagga tataacaatt tcaatacatt catcgtcaat cttctgcctt
     7021 ttcctgcaaa aggataaaca tgcatatgca tggctggatt gaaatttgct tcgatgatcc
     7081 catatgcttt tttatcagtt gtaggatcga tttctttatc tggtataatc aaatcgatac
     7141 cactaatctt agctcctagt gcttctaccg cagaaacggc gatttttttg taagcttcag
     7201 aaaattcatc agtcatatcg atcgaatcac cacctgtact gatatttgag ttctccctta
     7261 gataaacaat ttgattggct tggggaactg attcgatcgt caacccttgt tctttcaaca
     7321 tcaattgttc taattcacct aattggatca attctaaagg tgcacgatga ttcgttccac
     7381 gcaaagggtc actatttttt tcttcaacaa gttctttcac tgttcggata ctgtcaccaa
     7441 taacattagc agggactcgc aacatgatgg cttggacttc tccgtcgatc acaaagaaac
     7501 gatattccgt tcccggcata aattcttcta ctaaaaccga actgtcttca cgaaaagcaa
     7561 tggctaaacc tgcttgataa tcttccagac tagctccttc cttgaaaatc gtgataccta
     7621 acccgtaatt ggttgattta ggtttgatca caaatgcctg ctcggcaaat ctcggataag
     7681 cttttaccgc ttcttccatg gatgaaaatt ctgcgcctcc tggtacccgg aacccagctt
     7741 cttttaagac ttttttcgtt actgttttgt tttccatgat aagtgggacg atatagctgt
     7801 ccttacttgt catgtttgca tttttcacat attctacatg gtcttggaat tgcagacgca
     7861 aaaattgatc cgactcatct aatactttga cttggacacc tttttggatg gcatcgaaca
     7921 taaatatctg agtagaaagt tccatttcgc gaaaaccggc caactgatag ggacgttcat
     7981 ggctttcttt ataatattga tgtcccaatg ccacagcaac ttcttgctga ctcgatagct
     8041 gtgcttcttg atagagtttc gctgctaacg tttgttcagg atgatccatt tgagtcaatg
     8101 cttcctctac taaataaaga gaatccaacc aatccaattc aaccagcatt tgcttcattc
     8161 cttcaagaat ttctctacct tcttgatgaa attctgtttg atctgatggt tgttctagtg
     8221 ctactttgtt atttcgagtc gtaccttctg ctacccattg gtcacagtct tctttttctt
     8281 ctgtccataa catgtacatc aggaataatt gtaagaaccg aacttgctct ggattgatac
     8341 ccaatcttgc ataaggattc aaatcgatat tccgcaattc aatataacga acacctgttg
     8401 ttgctaaatc tgcgactttc tttccgcctc ggaaacgaag cggtgtataa aattctttct
     8461 cctccgaaag tttcccttct tcgatcattc gctcgatatc tgctaaatac tgtttcatag
     8521 aagcatagga aactttcaca tttggatgat tcgtatagcc cagcgcactg ttgcgaatac
     8581 tgcgaacagg ttcttgcgga tgtgattcat ctaaaaagta gttcttctca ctcattggtg
     8641 aagcaccgaa taaataagtg atcatccagc gatagcgcat aaagtttctc gctgttttca
     8701 aataaagttc tgttttgaat tcggaaaaat cttgaaattc ttcctgatgg ctgaacaatg
     8761 ttcttagcaa ctcatcgcca aattcaaaat tgaaatgaat accgcttacc atctgttttc
     8821 gcttcccgta ttcttttgct aaataacgtc gatacaagac atcttcgaaa ttttttaatt
     8881 ttgcaataat gatctcttcg tctttttccg gtaaggcagg tggcatactt aatggccaga
     8941 tcatctcttc tttcggtata gaacgagcag tcacatcata aacagcagcg agatactgaa
     9001 ataattcggg aatagaatcg gtaacagggg tgatcatctc tgtttgtgtt tcgctaaaat
     9061 ctgtttggat ataggggtga taggatcgat cgccaaagat tgctggatga tcggtttttg
     9121 ctagatttcc tgcaagatca acccgctgtc cttcccgttc tataccaaat cgagcttggt
     9181 cgataaaagg gcgcgcattg acatgcaata ataattgctt aaaattcatc attaagtgac
     9241 ctccaattca tatgaatcta attataatca aaaagtctaa gaaaaagaac gaaattgttt
     9301 gagaaccgct tacaaataag tataaaaatg aaggcatcaa aaacacagct atgttaaaaa
     9361 caatcattca aacaaggagc tgcaactttt gtcacagctc ctgcttttta gacatgggtt
     9421 attcttcttt tagtaatcct ttgaacaatc caacgacaaa atcatttgga tcaaacggct
     9481 ccaagtcatc gattccttca ccaagaccga ccaatttcac tggtaaatgc aattcattac
     9541 ggatagcaag tacgataccg ccctttgctg taccatctaa ttttgtcaaa acaagaccgg
     9601 tcacatctgt tgtttctttg aattgttttg cttgaaccat cgcgttttga ccagtggttg
     9661 catctaatac aagaagtgtt tcttggggtg cttctggtaa ttcccgctgg attactcgtt
     9721 ttattttttc taattcgttc atcaagttca ctttattttg cagtcggcct gcagtatcaa
     9781 ctagtaaaac atctgcctgc tctgtctttg ctctttccaa agcatcgaat acgacagctg
     9841 ctggatcgcc tcctgcattg ccacgaacaa cttcaacacc agcgcgttcg ccccagacaa
     9901 ctaactggtc gattgctcca gcgcggaagg tatctgctgc tgccatcaat acttttttac
     9961 cttcgttttt gaactgatgg gcaagtttac caatacttgt tgttttccct acaccattaa
    10021 caccgacaaa caaaataact gttagtccgt cttcttggat atttagttca tttacttcat
    10081 tgattccttc cgcttcatag agatccacaa gtttctcgat gatcgcattt tggacttctg
    10141 ccgatttttt cgcatttctg agtttcactt cttgacgtaa tgcttcggta attcgtatcg
    10201 ctgtttcaaa acctacatct gcaccgataa gtgtttcttc taattcttca aaaaagtctt
    10261 catcgactgt tcgaaaattg gcaaacaact cattcatccg ttcaccaaat gttttacgcg
    10321 tcttttctaa acccttgtcg tacttctcct gtacttcaac ttcttctgtt ttctcttcgc
    10381 cagtaaaagc acgcttgatt ttatcaaaaa atcccatttg actcccccta ctctaataca
    10441 aatttttgga tcactttggc tacgccattt tcttcattgc tggctgtcac gaaatctgct
    10501 gcttctttga cgaaaggcac agcattctcc atcgctacgc ctagtccagc atattggatc
    10561 atcggtaaat cattttcctc atcaccgatc gccatgattt cttcttgttt caaaccaaga
    10621 tcttttgcca ataaagaaat accataagct tttgtaacac cttttggcat aaattccaaa
    10681 agcatacttc ttgttttgat gatctcatac atttcatgga attctgctgg tatttctttg
    10741 attttaggat ctaattcttc ttggtcataa gcgattactg ccttattaag cacaaattca
    10801 tctgtaatat cgcttatatc cgctggttgg aattgcagca gcttattcaa cacattgtac
    10861 aaggattgct tccttggggc actaggcagc tgtaaaacca cattgtcaga caaaacatct
    10921 agtggcagat ccaattgctg agccagtttg tataagcgtt ggatatctga tacttccatc
    10981 actttctttt ccatgatttc accagtatca tttttttgta ccaaaccgcc gttgaaagtg
    11041 atgctgtagt caccttcatc taccagtcct aattcttgca gataatgcgc catcgcagct
    11101 aaggggcgtc ctgtacatag aacgatcttg accccttgct gttttgcttg tgctaatgct
    11161 tgtttattct catctgaaat cagcttttgt tcatttaata atgtaccgtc caaatcgatt
    11221 gctactaatt tgatcatttt cgttcctaca ctttcgtttc gttgattttc gcctcttcat
    11281 tgatatcttc catccgtaca gaaacgattt ttgatacacc ggattcctgc atcgtcactc
    11341 cgtacagtac atctgctgcg accatcgttc ctttgcggtg tgtgactacg ataaattgtg
    11401 tgtcatcttg gaaatcgctc aagtaacgac caaaacgttt cacgttggct tcatctaacg
    11461 ctgcttctac ctcatctaag atacaaaacg gaacaggaca gacacggata atggaaaaga
    11521 gcaacgcgat ggctgtaagt gctcgttctc ctccagaaag caaacttaga ctttgcagtt
    11581 ttttgccagg aggttgtact tcaatctcaa tacctgtttt cagcaaatca gttggttccg
    11641 tcagtactaa ttcagcttta ccgccgccaa acatatttgg aaagacaatt ttgaattctt
    11701 gacggatagc ttcaaatact tctttgaatc ttgtccgcac ttcatcatcc atctcatcca
    11761 tcgtttcaaa caattggttt ttcgctgcta acagatcatc tcgctgtgtt gctaagaatg
    11821 tatgtctttc actgacttgt tcgtattgtt cgattgaatt taagtttact ggtcccagtt
    11881 tttcaatctg ttcttttaag gatgaaacct ttgttctact gtcttcgata tcggttgttt
    11941 cttgatagtc ttgggaagct ttctcaaatg tcagctgata ttctgactgc agataggtca
    12001 aatgattatc taaaatcatt tcagctcggt ctttttggac ttctaatttg gattgttccg
    12061 acagtcgtgc tttttgctca cgattacgct ctgccaagac tgcttcaagc ttatcgatct
    12121 ccttttgcct tctatctcgc tgctctttgg cttttgccaa ctcggctttt aatgtttctc
    12181 gctgagcaga taattcgtta atttgttttt ccaaactttc ttctgtgact tcatgatcag
    12241 aaaagtctgc tgtcaatgtc gccaactgct tttctatcgc ttcttgacgt tcggttgcct
    12301 ctgctttttg gactcgggca ccgcggagct ggatctgcag atgattaaac tgctctttca
    12361 agacagcaag atctgcttgt tcttgtgctt tttgactttg tacttgtgct cttctggctt
    12421 ccatctggtc gctttcttga cttaacgatt tgatttcttc gtcgattttt tgtcgttgcg
    12481 attcaagatc tgtttgtttg tctttcaatt cgttcgtttg cttttcgtaa tcttcgataa
    12541 actgctgcag ttcacgtgtc tcaaaagttg agatttgctt ttctttttca aaacgttcaa
    12601 gttcatttat gatgttttgt agctgatttg tcgcttcttg ttcttcaaaa cgtaattgtt
    12661 cgcctcgtgt acgcaaaact tcttgttctt cggctaaacg agctgtttct tgttgcagct
    12721 cctgaacttt tttttcttgt gcttggagtt gtttatctgc ttcttcaaat tcactagtca
    12781 actgtttcaa ttcttgattt tgtacaaaca aactgccttg gtttcctcgt ttattcgctc
    12841 cacctgtcat ggatcctccg gcattcatca catcaccttc taaggaaacc actcgatatt
    12901 gatagcggat cgtttgcgcg attgcattgg cactagttaa gtctttggct aaaaggatcg
    12961 ttcctagcag gttttgaacc acagtttgga tttgatcggg ataactgact tgttcactgg
    13021 caatccctat aaacccttct acagctgctg cttgtgtcaa tatatgagcc ggtaattgtc
    13081 ttggtttgat tgtcgtcagt ggaaggaatg ttgctcttcc tcctctttgc tgtttcaaat
    13141 acgtgatggc ttgccgagca tctttttcat tttcaacgat gacatgctgg gctgccccac
    13201 ctaaagctgt ttcgatagct aacgtgaaat ctgcaggaac atcgatcagt tcagccactg
    13261 ctccgacaat acccgaaagc tgctgtttat gctgcaagac caatcgaacc ccttggtaaa
    13321 aaccaaaata gttttcttgg atttcttgaa ggcttttctt acgagcacgt agctgctgga
    13381 cttgattcat taattgatac attttaggct gttcttttgc taatgcttct tggaactttt
    13441 tcccgttttg ttggatcatt tctaacttct cttttgtttc agttaaagat gattttagct
    13501 gcgcctgctt ttgtgtcaat tcttcttttt gtaagatcaa tcggtctact gatgcttcta
    13561 cttccgattg cttggctaac gtctgcttgc tttttgctgt ttcttgtata tattgacgtt
    13621 ctagatactt cagttcgttt cctacagctg cttgttcttg catcaaatca acatattgat
    13681 ctcttaattc tgccaataat tctttcgttg atttttggta tttttctaat tcttgctgtg
    13741 tttttatgag atttgcttca gctttttgga tctctgtttc tttttctgct gctgctttca
    13801 tcaagctttc ttgaagcttt tcaaaatgtt taaccttttt ttgtgcttct gctaatgaag
    13861 tttgatattc ttgcgagctt ttttgtgtat gctttgtccg ctcctgcaaa acatcttttt
    13921 gtccttctgt ctgcttcagt ttttccgaaa gatctaataa tacttgctga tttttttcga
    13981 tcagacgatc ggcttgcgca ttttctttac gctgcttcgc caaaatggat tcttgttctt
    14041 ggatcgactc agatagtttg cctaattcta gattgaattt cgcaagctgt gcttgtttgt
    14101 tgtcccaatc tttttttgct gtcttgattt cagcaaccat caaagagaca tcggtttgag
    14161 tcagtgtttc ttttagccgt aaaaactcct ttgctgcctc actctgggcg gccaaaggag
    14221 ttaactgttc ttccaattcg tggatgatgt cttggacgcg gctgaggttg tcttctgttt
    14281 caaaaagctt ctgttctgct ttctttttcc gctgcttgta tttcaagaca ccagctgctt
    14341 cttcaaagat cccacgacgg tcttccggtt tactactgaa aatcgcttct acttttcctt
    14401 gagaaatgat tgagaacgat tcttttccta atccagaatc taagaacaat tcttggatat
    14461 cttttaatct gcagctttgt ttattgatga aaaactcgct ttccccagtc cgtcgataac
    14521 ggcgggttac actgatctca ttgtactcca atggcagata atgatcacta ttgtctaaaa
    14581 tcactgtgac ttctgcaata ttcagctgct tacgggtatc ggaaccggca aagatgatat
    14641 ccggcatttt tccgcctcgc agacttttag cagattgttc tcctaatacc cagcggatag
    14701 cctctgtaat attgcttttt ccgctgccat ttggtccaac cactgctgtg acgctatttt
    14761 caaaatcaat gactgtcttg tctgcaaatg atttaaaacc ggctatttca attcgtttca
    14821 aatacaaagc tttccctcac ttacttttac agtgctgcca atgcattttc cgccgcagct
    14881 tgttctgcta attttttcga tttcccttgt ccagtgccaa tcaattgatc atctacataa
    14941 acttcgatcc aaaatactcg ttcatgagct ggaccttctt cattgatcaa tcggtattcg
    15001 attgatacat cacctgattt ttgcaagact tcttgtagtt ttgttttatg atccatctca
    15061 tgtgaaaaag cacctgcttt gactttagga aaaatcactt tttcgatgaa tgcatgggtc
    15121 gtgtcgaatc cctggtcaag atataacgcg cctaaaaaag cttcgaatag gtcgcaaagc
    15181 aatgctggtc gcgtacgtcc tcctgaattc tcttctccct tgcccaacaa aacatattga
    15241 tcaaagtgac attctttggc aaatttcgac aagctgtctt cgcgaacgat cgcagctcgt
    15301 gtttttgtca attttccttc tggcaaatga ggatataaac ggaataaata ctgagaaacc
    15361 atcagttcta aaacggcatc tcctaaaaat tcaagtcgct cattatccga taattgcaga
    15421 ttgcgatgct cattcacata ggatgaatgg gtaaaagctt gttcaagcaa atttagatcg
    15481 tgaaaaacga tgttatagtt ttcttttagt tcttttgtca gctggttgtc cattttccac
    15541 attcctttta tggatatttt ttcgatactt ccttattata ctggtttttt gtcaaatttg
    15601 aaatggttcg gtcaaaaggt aagtaaagct ttaataatcc tagtgattga cgagaagttg
    15661 tgaaaaattc gtttagtttc gagtatgaag aaaaaatttt gtgaaaatgg ctttccatat
    15721 ttttgcataa atttgactta ataccgagaa actggacttt gaacaccgtt tattggagaa
    15781 gtcatgaaat cagcgccttg acctgaatat tagagaaata aacagaaaaa tatcaaaaaa
    15841 ccgaaaaagg acatcgccct ttttcggtca tttttagtga ttatgaacgt gaatctgctg
    15901 taacagaaac atttgcccat gggtttggta catcataaga ccaatcccag tctttgacac
    15961 ggtcgttgac tggcaatact tcattacgga acaacgttgg aatcgcaaat gcttcttcaa
    16021 atgcatattg ttgccatttt tgatatgctt ctttttggta ctcttcatca aatgctttgc
    16081 ttgaactgat atcgttgatc aattttgtat tttcttctga ttcataacga gtgtagttga
    16141 acgcagcatt tggtccccat agtccacttg gatttggatc agttcctgta ttccaagcag
    16201 cttggtaaac atcaatttca ggatcatcgt tttctaattt atcatagaaa gaattgaatt
    16261 cgatcagacg acctgttgtg tattggacat ccaaaccaat ttctttccat tgttggatat
    16321 agtaatctgc caatggttgc gctgtttccc caccggacat cgaagcaaag ttgattgtta
    16381 gtttatttcc atctttgtct tctcttaaac catcgtcatc cacatctttg tagccagcat
    16441 catctaatag ttttttcgct ttgtctagat cttgtgtgaa tcctttcatc tcatcatcat
    16501 ggtatgactg gaatactgga ggaatcaatg aagtcgcatt gcttctcaaa cctgcataga
    16561 aacgttcacc tactgcatta ttatctaatg catagcccat tgcttgacgt aatgatttat
    16621 cagccatttt tgaatctgga ttgtattcca cactctttgt atctgcattc catttaccta
    16681 acttgaatcc tagataagta taagaagttt gttcacggcc taagtttgta tagccagcaa
    16741 tttctttata ggtatcgtaa gtatctgttg gcatttggaa aatcatatca tataatttag
    16801 agttcaatgc ttcagttgca cttgccatcg gtacagattt catcgtgatc tttttcaatt
    16861 taggcgtacc attccagtag tgctcgtttg gcaagtattc tactgattct cctgcaacga
    16921 tattactcat gtaataaggg ccaaaagtca ctggattttt acgtacttga tcgcttgatt
    16981 ccatatcttt gattgctaca ccttctaacg tatgttttgg tgctgcatat gaccagatac
    17041 caccacccga ttgaagcatg cttgggttta cttctttata ttcgatttca actgttttgt
    17101 cgtctatttt tttgattccg gagattgtgt cggcacttcc atcatgatat tcttccatac
    17161 ctacgatgtt acggaaagtg tcgtcataac ggataccagt gtaatcttta ttcccaatga
    17221 tttcgtaagg gaaaatcaca tcgtccgccg ttacatcttc accatctgac catttgacgt
    17281 tgtcttttac tttgattgtc gcttttttcg tatcttcatc tagatcaagc gttgcagctc
    17341 cgtcgtctgt gattctgaaa tcgtcatcgt ttgcaaatag cggttcatga gaaggagcca
    17401 taaaagctgc atcatatgaa tcttggtaaa actcccactg gaacaatcct ttaaactgac
    17461 tgtccgttgc gaccgcagct tctaattcgc cgtcttcgat tgcatcatca ttattttttg
    17521 ttgcaattgg aaaagttaat tcctctttgt tattgccgtt gcctccagag ttgtttccag
    17581 aggtatctgt acctccgccc ccgcatgctg caagaacgac agcagacatc agcgctgcaa
    17641 atccaaaaat cgttttcttc attcctattt cccccttcgc ttctatacta gcctaaccgt
    17701 tggcgcgcat ctgcagaacg cttgaatgct tgtccaacat aattgatact caacatcaaa
    17761 actaaaataa ggattgatgc gggtaaccag atccattgcc gattcactaa gacttctccg
    17821 ttacttgcat aaccgatcaa tgtacctaaa ctaggtacat ttgccggcaa gccgaaacct
    17881 aagaaagtca aagttgtctc gataccgatg tttgccgcaa agttcatcgt caaattagta
    17941 atgattaatg aacttagatt cggcatgatt tcgcggaaca tgattttaaa atcattggtt
    18001 cccattgttt ttgaggcact gacataatct cttcttgctt cagataatgt cttgcttcgg
    18061 aataatcggg ctttagctac ccaataaaat gcactcatga tgaatataaa ggaccagaca
    18121 ttgtatctgg aaataatcga tacgaagacg ataatgatca gcatgatcgg tagaatcatg
    18181 ataaaatcaa cgatccgcat caagatgttg tcaatgatcc ctccgtagta gccagagatg
    18241 atccctaatc caaccccgat gatcgaagta aggatcgtga tcgcaaatcc gatcgtaaca
    18301 gagtttctag cacctatgat caattgtcct aatacatcac gtccgccttc atctgctccc
    18361 agaatgaact tttgtccttg tgtcgaaact gttcctggtg cagcgtattt gtcgaagata
    18421 ctaacataca tcactttgtc ttgatcggtc agcatcgcac cgataaagat cactaataat
    18481 aaaaccacta gcaaacctaa tgaaaaaata gcaattttat cttttttaaa ttctcgagca
    18541 atcattcgta tccccatagg aggaatactt tcttgaactg ctgtattgtt tttttcactc
    18601 atcgatccat tctcctttct gattggtttt attgaatccg aatacgcggg tcaacgatac
    18661 tcatgatgat atctgaaagt aatgtcccca ctagcgtcgc gattcctaaa atcaatacta
    18721 aggatgtgat cacggtatag tcccgttggc cgatggaatc aataaatagt tttccgactc
    18781 ccggataacc aaaaatcttt tcgataacta cagaaccagc aatcaacgaa gtgatttcat
    18841 accccatttg agaagccatc ggcaacgctg catttcggaa aatatgtcga ctgaatactt
    18901 tattcgtcgg tacccctttg gaacgggctg ttctgacaaa atcgagcgat ttcgaatcga
    18961 ttacttcact tcgcagatat tggattgtga cggcagtcgc caaaaatgct tgggtaattg
    19021 atggtaacag aatatatttc aaacggtcta tccattgagt gataaatcca ccttgcaaac
    19081 ctagtgtttg tgatccactt gttgggaacc agcctaaacg ataaccaaaa acaaatagca
    19141 tgatcaagcc gaagataaat aaaggaacag caaaactaaa gaagttgtag attacgacaa
    19201 tcttatccaa gattgaattt tgataccggc cagcaagcat ccccagaggc acagcaatca
    19261 aataagtaag gacaactgtc aagatcgata gatataaagt gttgatgatc cgttcgccga
    19321 tcaagtcagc aacagagcgt ttgtataaga aactttgacc aaaatcgcct tgcaaagcat
    19381 ttccgatcca acggaagtac tggacatacc atgggtcatt caagccagct gcttgtcgca
    19441 tctgttcgat cactgccgga tcctgatttg gattgatcaa accggtaaat ggatcccccg
    19501 gcatcgcttg ggctaataag aagatcagaa cacttaaaat aataacttgc gggatcatca
    19561 ataaaacacg tcgcagaatc gttttccaca ttagcttgca cctccatctt tcaacgccac
    19621 tttgtgtgta gttgtgatcg tacgcaaatc gtagactcga ccagtcgcat catagtattc
    19681 tttttggttt tggatatact cttgttctac tcttcgtcga ttttctttgt ggctttccct
    19741 attttctaca tcgatttgcg gaatagctga aagcagacgt ttcgtataga tatgtcgcgg
    19801 gtcattataa atgtcttctc ttgtaccgat ttctacaaat cgacctttgt acataattgc
    19861 gatattgtcg cacatgtgtt ttactacacc taaatcatgt gaaatgaata aatagctgag
    19921 gccgtattct tgctggattc gtttcatgaa attcaatact tgcgcttgaa cagatagatc
    19981 cagagcagat acaggttcat cggctacgat cagttttgga ttggtagcaa cagcacgggc
    20041 tactcctaga cgttgacgtt gtccgcctga aaattcatga ggatatttat atagcgcatc
    20101 ttccggcatc ccaacgatat ctagcagtcc ttttaccttt ttcttttctt cttgatcgct
    20161 taaccgttca aaatttcgga tgggttcagc aatgatatcc aacactcgct ttttaggatt
    20221 caaactggac attgaatctt ggaagatcat ctgcacatcc ttgttataac ccattttttt
    20281 gcggttgctt cgcttcgtta catcttttcc ttcatacatg atttgtccgg ctgttacctt
    20341 ttctaatccc acaacggctt ttcccgtagt agattttcca gagccagact ctcccactaa
    20401 accatatgtc tttccttttt cgataataaa atccacacca tctacagcat atacatgatc
    20461 cgttactcga ttgaagaatc cactgcgaat agggtaatga actttcaggt ctttgattgt
    20521 gattaattct gtcatctaca cctctccttt ttcgtctcta aagtggaaat gcttatagca
    20581 ggagcaacgt accaagtggt tcggtgcgac ttcatgaagg ataggctctt cttcatgatc
    20641 gcttgctggt atccatggaa tacgtggtgc aaaccgacaa cctttacgag gcatgttttt
    20701 cagagaagga acgacacctt cgatcacatg gagttctgca tcatgatttc cttcttgtgg
    20761 tatagagttc agtaaagagc gtgtataagg atgcttagga tgatcaaaca gttcttttac
    20821 acctgctact tcaacgaact gtccgccata catcactgcc actcgatcag ccatttctgc
    20881 tacgactcct aagtcatgag tgatcaagat gatccctgtt tttgtttctt cctgaaggtc
    20941 tttcagtaaa tcaagaatct gtgcttggat ggttacatct agggctgtcg tcggttcatc
    21001 tgcaatgacg attggaggtt tgcaggcgat tgcgattgcg atgatgacac gttgtctcat
    21061 accgcctgat agttcatggg gatattggcg tccaactctc gcaggattag gaatccctac
    21121 ttgttctagc aattctagtg cacgagcttg acgctgttct gcattcatct ttgtgtgata
    21181 ggaaagtcct tctttgatct ggtcttcgat tctcatgaga ggatttaatg cagacaacgg
    21241 atcttggaaa atcattccga tatcatttcc gcggatttta ttatagagcg tttcgttcag
    21301 gtcgattaaa ttcagatcgt tatataaaat ctcacctgta atttttgtgt tattaggatc
    21361 aagtaatccc ataatcgtag tagccaaggt acttttcccg cacccagatt ccccaacgat
    21421 tgctaaaatc tcgtttttgt ctaaagtaaa tgaaacgtca tctactgcat cgtaatagtc
    21481 atctttgagt cggaatcctg tatgtaggtt ctgaacttct aataattggt tatcggacaa
    21541 tcgaataccc ctctctgctt cctaaatgga agtttttctt aataaaaaag gacattacac
    21601 agaataaatc gttttata
//
LOCUS       DARBDN010000042        21117 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000042 DARBDN010000000
VERSION     DARBDN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.042"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..276
                     /locus_tag="SCH06_001510"
     CDS             1..276
                     /locus_tag="SCH06_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078091.1"
                     /translation="MEKLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKE
                     KSEPKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            288..557
                     /locus_tag="SCH06_001511"
     CDS             288..557
                     /locus_tag="SCH06_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078092.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            562..726
                     /locus_tag="SCH06_001512"
     CDS             562..726
                     /locus_tag="SCH06_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078093.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            719..1021
                     /locus_tag="SCH06_001513"
     CDS             719..1021
                     /locus_tag="SCH06_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078094.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            1018..1179
                     /locus_tag="SCH06_001514"
     CDS             1018..1179
                     /locus_tag="SCH06_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEG1078095.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            1176..1481
                     /locus_tag="SCH06_001515"
     CDS             1176..1481
                     /locus_tag="SCH06_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078096.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            1481..1837
                     /locus_tag="SCH06_001516"
     CDS             1481..1837
                     /locus_tag="SCH06_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HEG1078097.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            1824..2042
                     /locus_tag="SCH06_001517"
     CDS             1824..2042
                     /locus_tag="SCH06_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078098.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            2039..2458
                     /locus_tag="SCH06_001518"
     CDS             2039..2458
                     /locus_tag="SCH06_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HEG1078099.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            2455..3012
                     /locus_tag="SCH06_001519"
     CDS             2455..3012
                     /locus_tag="SCH06_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEG1078100.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            3009..3305
                     /locus_tag="SCH06_001520"
     CDS             3009..3305
                     /locus_tag="SCH06_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078101.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            3382..3795
                     /locus_tag="SCH06_001521"
     CDS             3382..3795
                     /locus_tag="SCH06_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEG1078102.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            4141..4515
                     /locus_tag="SCH06_001522"
     CDS             4141..4515
                     /locus_tag="SCH06_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078103.1"
                     /translation="MEDKMYLRQKVFTKKDIENQINGFIQKLENANSYLINKELNKAY
                     DQWKEVYDELKLIQNETKLVRTEKKNENSFFFDGYAILMLETVAKQNIKAPKKELSDN
                     IDNALAELRYYVMQIKDVRITR"
     gene            4552..4719
                     /locus_tag="SCH06_001523"
     CDS             4552..4719
                     /locus_tag="SCH06_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078104.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            4745..5089
                     /locus_tag="SCH06_001524"
     CDS             4745..5089
                     /locus_tag="SCH06_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEG1078105.1"
                     /translation="MNEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            5094..5375
                     /locus_tag="SCH06_001525"
     CDS             5094..5375
                     /locus_tag="SCH06_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078106.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            5478..5792
                     /locus_tag="SCH06_001526"
     CDS             5478..5792
                     /locus_tag="SCH06_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEG1078107.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            5770..7464
                     /locus_tag="SCH06_001527"
     CDS             5770..7464
                     /locus_tag="SCH06_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEG1078108.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNANLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            7484..8662
                     /locus_tag="SCH06_001528"
     CDS             7484..8662
                     /locus_tag="SCH06_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEG1078109.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            8625..9311
                     /locus_tag="SCH06_001529"
     CDS             8625..9311
                     /locus_tag="SCH06_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEG1078110.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            9311..10471
                     /locus_tag="SCH06_001530"
     CDS             9311..10471
                     /locus_tag="SCH06_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEG1078111.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGRLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            10481..11356
                     /locus_tag="SCH06_001531"
     CDS             10481..11356
                     /locus_tag="SCH06_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078112.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWARLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            11353..11664
                     /locus_tag="SCH06_001532"
     CDS             11353..11664
                     /locus_tag="SCH06_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078113.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            11654..12007
                     /locus_tag="SCH06_001533"
     CDS             11654..12007
                     /locus_tag="SCH06_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEG1078114.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            11997..12398
                     /locus_tag="SCH06_001534"
     CDS             11997..12398
                     /locus_tag="SCH06_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078115.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            12391..12795
                     /locus_tag="SCH06_001535"
     CDS             12391..12795
                     /locus_tag="SCH06_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078116.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            12807..13415
                     /locus_tag="SCH06_001536"
     CDS             12807..13415
                     /locus_tag="SCH06_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEG1078117.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            13435..13797
                     /locus_tag="SCH06_001537"
     CDS             13435..13797
                     /locus_tag="SCH06_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078118.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            13800..13982
                     /locus_tag="SCH06_001538"
     CDS             13800..13982
                     /locus_tag="SCH06_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078119.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            13999..17418
                     /locus_tag="SCH06_001539"
     CDS             13999..17418
                     /locus_tag="SCH06_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEG1078120.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNTLAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     VTAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGESGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRTQAVQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            17469..18206
                     /locus_tag="SCH06_001540"
     CDS             17469..18206
                     /locus_tag="SCH06_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEG1078121.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            18216..20507
                     /locus_tag="SCH06_001541"
     CDS             18216..20507
                     /locus_tag="SCH06_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEG1078122.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKALAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLHHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            20531..>21117
                     /locus_tag="SCH06_001542"
     CDS             20531..>21117
                     /locus_tag="SCH06_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078123.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIQKYNETFDAFMAEIEGRVDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSI"
BASE COUNT         7587 a         3100 c         4541 g         5889 t
ORIGIN      
        1 atggagaaac tcaaaacaga attccctaat gattaccaag agcgaatcga acgactgtca
       61 gagtattgtg aatcatctgg taagacttat aaaaactatt tggcaactat tcgaagttgg
      121 gcaaggaaag aaaaaagtga acctaagaac gcaagcagtg gatacaagcg cacaggaaga
      181 cgagagaagc ttcctgaatg ggcaatcgac caagaagcct atctcaagaa aaaagcgcta
      241 gaacgagcta atagacaatc aaaagcacca ttctaagagg tggaaaaatg aagatcgatt
      301 atctagaact aattaatgaa atagcgaatt ataaaaaggg cgaggaatta gacgtcctga
      361 gagacgtata tgatcaactc gaagaagctg gaattgaagg aattaagaat gatcgttcga
      421 gttggagtaa gctcagatac tatttcgcac tttatatcga tacaacacaa ttaagaaatt
      481 tagcatatac caaattacta tttgttgatt gtgttaaagg cttgcaaaaa catcttaatg
      541 aacttgagca ggtgtaatca gatggaccta aagacattta cagcacagat tgaactaatg
      601 catcaagaag ctttaagaca aagtgtatcg tacgaagaca agtggctcaa cacgttccat
      661 ggcggacgtg agagcgcact tgatcaagta ctcaaattac tgaaaggaga atgtcgggat
      721 ggataagaaa gcggcaatgc agcgaattat cgaattgact tattcagaag attggcaaaa
      781 tgacaaagaa gctgcttcag aagtgatgag gcttggaaga gcgatgtggg cagacaagag
      841 caacaagcca agaccacgaa aaatcgcaat ttggcacggt gacaaacttc tagtgatagg
      901 gacagctgaa cagttagcaa gtctcacagg cttgcacgag aaaatcgtga ggaaaagagc
      961 aaggtgtggc tacacagacg ctaagaagag aacgtttaga tacgtggagg aatcatcatg
     1021 acaacagaag aagtgattca aatgcgtatt cgaagccttc agcgtgagat tgacgatctg
     1081 gaacgaacaa aggcagtgat ggtcaatgaa acggcgagaa aggcaatcga tttgcacata
     1141 gagaatttaa gaagggaaat ccatcgattg gaggaatgag cgtggataag aaagcagcaa
     1201 tgaaaagaat tgctgaatta accaagtcag aatcttggca agaagacaaa gaaatagttg
     1261 cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa gcccaaacgg agaacgccga
     1321 gaaaaattgc aatctggcat gatgaccgaa ttttagtaac aggtactgct gaacagttat
     1381 ctgaaattac tggattaagc aaaaacatta tctgggatag agctaggagc ttatggattg
     1441 attcaaaagg acgacagttt aggtatgtgg aggagagata atggatctca ttacacaata
     1501 cagtgacatc atcctcaaga aaatcatgat gaagattcag aaagataaaa aatcaaaaga
     1561 acgagctgaa ttagttaagt tagaaatggc tgaaacagga gcaggagtgc gaagtagcag
     1621 gcattggaaa gcagcagcaa acattgaatt ttattacaac gaaattcaaa aagggttcga
     1681 tcagatgcgt gagctggatc ggcaaacaaa ttggagcaag aaacttcatc aagatcgttt
     1741 caaatttgta gagaagtata aagaaatatt agaagagtat ttgaggagga cagcaaatga
     1801 taaaaaaact cgttcaattc agcatggatt tatatgatat cgaatcagga gcaacactat
     1861 ctgtggaatc ggaccatcta atcataaatt ttggtggaaa gcgccagatt attttgtggg
     1921 tagttgatga tgtactgttt ccagaaattg ttcatgattt cgaagaatca aaagcggttg
     1981 agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag gacagcgaat
     2041 gataccgaag tttagagcgt gggataaacg aaagaacgta atgagagatg tagccgtctt
     2101 gcattttact aaaaacggca aaacaaactt tattgaatat tggataaatc ctaccgaatt
     2161 gaaatcatat cacgtgcgaa acatcgacct catgcaatcc acaggaatga aagataagaa
     2221 tggtgtggat atatttgaag gggatatagt attagtcagc gtgcgaaatg gcttcgatta
     2281 cttagataat aaagtctgta ttgtcaaaaa ttcaatagat tattccggat tagtttgtgc
     2341 cactgttgat gaagacttag agtatcaaat ttttaacaca gagctgtttg aagaatacac
     2401 gtacgaagtc accggaaata tatacgagaa tagcgagtta ttggaggaac agcgatgaat
     2461 aaacaggaag caatcaaaaa gttagaaagt attaaagcga taggaaatga tgcaatagct
     2521 gcttgctata acgagagtat aaattcaggt attacgttaa tgaaaaaaat agacgaaccg
     2581 cagaaaccag ttattccaca actcgtggcc ggttggcttg agaaatctac ggaccctttt
     2641 acaaaagctg aaaaaatagc gtatttaatc aaatctaaag atggtgattc atattatttc
     2701 tgtgattggt ttgtacgaga tggcatagtg acgcaagagc aaggagaaga attactcgct
     2761 tgggcaacaa gacaatcata tgaaacacta ttgagcctat acaacggcta cgaggttgag
     2821 aaagagccgt tatgggcaat aaagaatgcc gatggaaact atcttactaa atgtgcttta
     2881 tggggaaaag atggagtaaa ttatagtttt gaatgcaatc catctcatcg attgcttttc
     2941 actgataaag caacagcgga tgctgcagca ttgttggtga atggaacagt ggaagaggtg
     3001 gtagaaagat gaaactaaaa gacggatttt acgctagcag tcacggtatc ggcggtttaa
     3061 tgctagatat gccgacaaag aaccctaaaa cacgcaagaa atcaaaattc aaagtcggtg
     3121 acatggtccg ctgtgaagca gaagagttcg tttatccgtt cagaggatac gttaaaaaga
     3181 tactgtcaaa ctcagcaatc attcgtattg aaaatacaat gaagtgtgat cgttcgactg
     3241 caaaacacaa gcattattta gctgtagcga gattagttga catggaagta atcaagagca
     3301 aataaaaaaa gccggatcgc tccgactgat tcaataaatc caacacattt attatatcac
     3361 ataaaggagc ggtttgactt gatgcaattg ttacgagagg tagatttcaa acagacaaga
     3421 tgtaatgcga gagatgtgct gaagaacttt cggcgtttgg agcggatggc aggtcgctct
     3481 ttgatagata ttaagtcgcc gattattacg gatatgccga aggcaccaaa gcacggcaat
     3541 aaggcagaag acgcgatcat tcagatgatg gatatagaag cggagagaga tgcgattcta
     3601 gcggctttga tggctcttag tctaattagt cgccagatac tctactacag cttctgtgtg
     3661 ccagatagct tctcaaacta caggattagc cgtgaagtgg gttattcaga aagaagtata
     3721 caacggatga agtcggaagc tctaatagag tttgcagaag catataaaca cggaagaata
     3781 attgcttata aataatttgg cggttttttg gcggaatgat ggcggttttt agctatttac
     3841 cagtgatatt atggtagtgt cgaaagatta gtgataggtc taagacaaaa taaaatgtaa
     3901 gggaggaaat ctccctcatc gtttaattaa gcttcgatag acagcagcaa ataaactaaa
     3961 ggatgtgggg gtcagctcct acagttagtt catgtgttgc tgtctattaa ttgcaactct
     4021 ttcggtttta ttgagtattt actcaactta aaaaaactgt tgtttgtaga tgtaagctgt
     4081 tcctatttgt acatagtaaa aaatgatata ataaaaatat tacgaaaggg gtgagagtgc
     4141 atggaagaca aaatgtattt aagacaaaaa gttttcacaa aaaaagatat tgaaaatcaa
     4201 attaatggat ttatacagaa attagaaaat gcaaattctt atttgataaa taaggaacta
     4261 aataaagctt atgaccagtg gaaagaagta tatgatgagt tgaaattgat tcaaaatgaa
     4321 acaaaattag tacgaacgga gaaaaagaat gaaaatagtt tcttttttga tggatatgct
     4381 atattgatgt tggaaactgt agcaaaacaa aatataaaag ctcccaaaaa agaactatct
     4441 gacaatattg ataacgcatt agccgagtta aggtattacg ttatgcaaat aaaagatgtt
     4501 aggatcactc gttgagtggt ctttttattt tgcacaaagg aggtaacaac aatgtataga
     4561 ccacaatact tagaacagaa gtatgaagta atcactgtgc aaaatggtaa cggagagata
     4621 gtacgaaagt atagaagacc aataaagagc gatacatata aacgaaagga aagcaatgaa
     4681 gttattccat tgtatggcaa aagaatagct aagcattaaa taagattgtg aaaggagacg
     4741 ggacatgaac gaggaattct atagatggct attacagttg ataagagaag atcgtttggt
     4801 taagttctat cagtctccta aatggcgcag gcttagagag aaagcgatga aacgagatca
     4861 ctatgaatgc caagagtgta gaagactagg taagtatcat agagtagaga acgttcatca
     4921 tataaaggaa gtcaaggata gacctgactt agctttagat ttagataatc ttatttgttt
     4981 atgtgttgaa catcataatg aagttcatgg cagatatctt acagcattgg ataaacaaga
     5041 gaagaagata gaaagctttg ctaacttcga tgcaagtgaa aggtggtaag tgcatgatca
     5101 tcaatgataa tggcagagag tatgatacag aaaagattga agagtattca tcttatactc
     5161 agggattaat taaacgtttg atatacgttc gctatgtagg tattagggat ctgttatcag
     5221 ataactgttg tagtaaatac aaagtgaatc aagtaagaga agcgttgaat aaagataata
     5281 acgtcgaaag aataaaaaat gtttttggat atagtattga agagattaat tattacattg
     5341 acttcgctga agctttcatt ccgatggtga gataaccccc ccttaaaata aatcgcaaat
     5401 tttttggggg tgatgaaacg gagggggctg tcaggaaaag agattttttc gaactttatc
     5461 atgaaaggag ggctaaaatg tttaaaaacg aattgtctca aaatcgctac agagaaaaat
     5521 tacgccgctc tttaataagc caattggaaa gtcagaaaac aaatattgag ccattcttag
     5581 ataatgttga tcgttatatc agtttatggg aaacggcgat atcactggaa gaagatatat
     5641 ccgagaacgg cattagactg gagaatggta aaaagaatga atcagtagcg ttgcttgttt
     5701 ctgtcaacaa acaaatggga ttgatgttgg ataaacttgc cattactcct gaattggtag
     5761 gtgaagcaaa tgaatcaatt cctgagttat aagcatattg aaaattggtt caaagctata
     5821 gaagaaggca ctatcaaggt atgcaaagag caattattgc taaaaaatta tctagaagaa
     5881 agagtcttta ctagagaaga tatttacttc gataagcaga tggtagagga ttcaatcaat
     5941 ataccagcac aatactttcc attcgaatta attccgtggg aaaaatttct acaatgtttt
     6001 atttatggtg ttcgatggaa aaaagataaa acactagtgt tcaatagata tctttcatta
     6061 atgggacgtg gtaatggtaa aactggtttt gcttcttgga acaacttctt tctactaacc
     6121 gctaaacacg gtattaaaaa ttatgatatt gatatctatg ccaataatga aagccaagca
     6181 aagactagtt ttgatgatgt atttaaagta attaaagatc atcctgattt agataaaaaa
     6241 gtatttaaag ctacgaagga agttattcaa aatatcgcta caaacagcaa acttcgttat
     6301 aacacggcaa atgctagaac aaaagatggg aagcgaccag gtgcaaaccg ctttgatgaa
     6361 attcacgaaa atgaagatta ttcaatgata aatgtggcta cttctggtgg tggtaaaatt
     6421 cgagattata gagaatttta tgatacaact aatggtcatg ttcgtggtgg tccgcttgat
     6481 gacattatag aagaatcaaa aatgattctt tctggagaac ttggaattga caaggatgga
     6541 gcagaatttt ctagtttgtt tccatttatt tgtcgcttgg ataacgataa tgaagttgat
     6601 gatcccgaca tgtgggaaaa agcttgtcca actattaatt acaatgcaaa tttaaaacgg
     6661 aaaatgtttc aagaatactc tcaaatgcaa cgtaatgctg gtttaagact tacgttcatg
     6721 accaaacgaa tgaacagacc tatggaagat acacgatttg ctgttgcttc atatgatgat
     6781 gttctgcata cgaaagaaaa agaatttcct gaaaaaatgg atgaagtgat aggaacagtc
     6841 gattttgctg atagacgaga ttttgccagc gttgggttgc taggaaaata cgataaagat
     6901 gtttatttta cacaacatac ttttatccac gaatcagccc ttcgattaca aaacatcaaa
     6961 cgagaggtta tagatatttc tatagatcaa ggaaaatcac agatcgttca tggaaaaaat
     7021 atagaagctg attatattgt aggttggttt cttgaaatga gtaataaata ttatattaaa
     7081 aaaatcgcta tggatatgta ccgtgcaaaa atattgaagc ccgctttaga agaagcaggt
     7141 tttactgtgg aaattgttcg aagcggatct gttacacatg gtatgttaaa agatctggtt
     7201 gatgaccttt ttattaatca acgtttattt tttggtgacg atgcgattat gcgttggtat
     7261 tgcatgaatg tatatgaaga gcatatttct aatggaaata tacgctatga aaaaatagaa
     7321 cctgaaacta gaaaaacgga tggctttttt tcattccttc atggtttgaa ttttttagat
     7381 gatatttatg attctgctcc tgtaacagtc acaaatagct cagtagaaaa tacaggaact
     7441 ggatttactc ctctagtatt ctaacttgaa aggaggtgag aaagtgggga tttttcaaaa
     7501 ggcggtagga tacttcacaa aaaaagcaac ggttccttta gaagaatact tttgtaaatt
     7561 gcaagttgat tttgtgtatc gaaaatttgc gattgaaact tgtattgatt tgattgcaaa
     7621 tgcgatgagt aaagcggaat tcaagtcata tgaagatgga aaaaataaaa agaatgatct
     7681 ttactatagg ctgaatgtag ctcctaataa gaaaaataat gcaacagaat ttagaaaaaa
     7741 actgatcagg agattaatat tctacaatga agtattgatc gtttctccgt ctaataattc
     7801 tagcgaaata tttattgcgg atagttggga tgtcacagaa tatgcattga aagatgatgt
     7861 gttttctcaa gtgcaaatta acaacatagt ccttgataga gaatttctag aaagtgatgt
     7921 tatctatata aaatacgcag atcaacaaat taggcaacta gtcgatgcgt attatcaagc
     7981 gtatgggaaa ctcatttcta gtgccatgaa tgtttacaag cgctctaacg ctcgtagata
     8041 cgtactgaaa gggaatttat tccgaccgca agacaataca acacaagatc aaatcaataa
     8101 aatgatgaca tcacaattta aggcttttat ggaagctgat aatgcaggtg cggtatttca
     8161 attacaaaat gagtacacat tagaagattt cagcggaaac ttccaaagca attcaagaga
     8221 tataaaaaac ttaatagacg acatctttga gatgacagca gcagcgtttc acgttccgaa
     8281 aaacctacta aagggagaca tgagtgggtt atcggatcaa gtggacgctt ttttaatgtt
     8341 cgaaatcata ccgattgctg aacttattca ggatgcgttt aacgctagtc tctatgaagt
     8401 agaagaatac ttgtcaggga attttgtacg tgtggataca actatgatca agattactag
     8461 cttcaaagat ttggttgacg ctattgatgt aggcattaga aatggagtat ttacaatcaa
     8521 cgaaggaaga gaacgcgttg gaaatgatcg ctctgataag gcgatggcag atgaaatatt
     8581 tataactaaa aacaatcaac aagtatcgaa aggaggtgag gcgaatgacg acaatgaaaa
     8641 catttctagc agtaaagaat gaaggcgcag taccgcaaat ttttattcag ggatttattg
     8701 gttctagttg gttctttgaa gggaatactg acaagggaat caaaaatatt ttggatagtc
     8761 taggtgatca agaagaaatt gaagtagtaa ttaattcaaa cggtggagac gtatttcaag
     8821 ggattgctat tgggaactta cttaagtcaa ataaagcaaa agttaacgtt gtgattaacg
     8881 gcttagccgc tagtgctgct tcaattatcg caatggctgg cgatactata aaaatctaca
     8941 acaatgcaca attgatgatt caccgcgctt ccacatacgg agaaggaaat gtcgatgact
     9001 tccgtacgat tgctgaccaa ctggaatcaa ttgataaatc ggtaaaggct tcatataaaa
     9061 cacgattcaa tggcacagat gaagcattgc aagaacttct tgaaaaagaa tcgtttatgg
     9121 atgcagaaac agctttgagt tatggattgg tcgatgaaat tatcgatgca gaaaatagct
     9181 caggtactga agctaaaaaa gaacaaagcg ttgaagaaat tttgaatgac gttaaagaaa
     9241 aaagagcaga aaaaattgct gcatttacag cagcattaaa taaaacattt ggacaaggag
     9301 atgtaaaata atgacagtta aaaatttaaa aggtgtaaca gctgcaagcg accaattgat
     9361 gaaagctttt aaagatggta acgaagaatc ttttagcgca gctatggtaa gcttatctaa
     9421 ggaaattcag gataaaattt tagaagaagc aacagcaaaa aatcaagatc aattagtatt
     9481 aatgaaccgt ggtcagcgtg tattaactac acaagaaaca aaattctata acgaagtagt
     9541 gaaaaacgaa ggttttgcag gggtcgaaga attagtgcca gctactgtat ttgaacgtgt
     9601 atttgaagat ttagaacaat ctcatccact attgcaaaaa attacttttg ttaacacaac
     9661 tggtgtaaca gaatggattg tgtcacgtgg agtcaatcca gcatggtggg gtaaactttg
     9721 cgaagctgtt aaaaaagttt tagataatgg ctttgatgta attaacatga agcagttcaa
     9781 gctatcaggt tatattcctg tatgtaaggc aatgcttgat ttaggtccag tatggttaga
     9841 tcgttatgtc cgtactgttt tagtagaatc attgagaatt gcattagaac aagcaattgt
     9901 tgatggtact ggtaaagata tgccagtcgg aatgatgcgt gacatgagca aacaaactag
     9961 cggagaatat gctgaaaaaa aagcagaacc tattacagct ttagatgctg taactatggg
    10021 ccgtttgatg gcgcgactat caaaattcaa tatcgaaggt gtgaatgatc cgatttatcg
    10081 taatgtgaat ccttctgatg tggtcctaat tgtgaatcca actgattact ggtctaaagt
    10141 attcccagct aagactgtac taactgctaa tggagaatac gtacaagtat tgccagtacc
    10201 agtttcagat ttgcagtcaa cggctgtgcc agaaggaaaa gcagttattg gggtagcctc
    10261 agattacttc atgggtgtag gatctacact aaaaattgaa gcttcagatg aataccattt
    10321 tgttgaagac gaacgcattt atctagctaa acaatatgca aacggtcaac ctaaacgtaa
    10381 cgatagtttc attgtattag atattagcgc tttgggaact actactacaa ctacaaaacc
    10441 aacaaccaca acaactacaa cacaagcgta ggtgatcaga atgaagtata ttctttgtca
    10501 gccggcaatc aatcggttta aatgggagct tgaagtttgt ttaactaatc tgaagaaact
    10561 aggaatcaaa gatatcgtat tgcttttcag cagacacgat gatcagattc ctattttttt
    10621 tgagaaggaa tatggtgttg aagttcatgt gtacgatgat ctgcgggacg acaaagagta
    10681 tattccttcg attaaaccat atttatggtg gaaatattta gaagaagatc attcgcgtga
    10741 ggacgaccga tatttctata tcgattcgga tgtcattttc aataaaagaa ttaatttgcg
    10801 caaattgcct tctaaagatg atgtttggta ttgtagcgac tgctgtagtt atctaagtct
    10861 tgattatatt agaagctgtg aaaacggaga aaatattcta aaagatatgg caaacattgt
    10921 aaatgttaca gtagaatctt tggaaactat aaacactaat tcaggaggcg cacagtgggt
    10981 tattaaccgt cctaaagcga attattggaa aaaggtttat ctggattcta atcggctata
    11041 tcgctacctt agagggcaaa aaacaaatat acaaatttgg acagccgaga tgtgggcacg
    11101 gctttggaac atgatgtatt tcaatattgg tcctaaagtt cacgaggaat tagacttttg
    11161 ttttgctact gatccaatag aaaaagttaa agaagtaaaa atcttacaca atgctggagt
    11221 aacaacaaac gatgaagatt tatttttcaa agggagatac gtgacttcta cgccttttga
    11281 tgaagattta tcatttgtaa acaagaaaaa atgctcttac gcatatgtta aagcaattaa
    11341 ggcggtggtt agatgacgcc tgaacaagtg actgaagaat tgctaatagc tgtgaaggat
    11401 aatatttacg ttacctggaa cgaagaagat gagtcaatta aaaagatgat agctaaaaat
    11461 gctgtttatc ttcaaagtaa agtgagtaca acactttctt tttctcctga aagcttagaa
    11521 tacggattgc taatcgaaag atgtagatac gactggaatc gtgctttaga tgagtttgaa
    11581 caaaatttcg ctagtgagtt attaggtttc attcaacatt atgcgctaca agaatatatt
    11641 gcaggtgatg tgaatggcga ataatcgtag actcgaagaa acattcaacg atggttggtt
    11701 aaagattttg acgcaaacta ccaaaagaaa tgaactagga aaaaagattg gtgtagaaga
    11761 tacagaaatc acttctttaa aatttagaaa tctttccatg agagatagtg atataacagc
    11821 tatggatgcg atgggatcga aattaactaa gaaagtaaag actccatttc atccaatcgc
    11881 caagaaattt aataaagatc aatattttat cgtaatcgat agtatgcgtt acaacgttat
    11941 ctatgccgat tacgataatt tttatatcta tttttatctt gaaagtgtgg gtgaatatgg
    12001 tgattgataa ttctaaagaa aaagaacgtt taaataagca aatttctgct atcaaaactt
    12061 ccttagaaga gcattttggc ctcaaactct ttcaagactc cgtaggcgag gatgagctac
    12121 ctgatgattt taattacttc attctcgaaa caggagaaat agaaatgatc actgagccaa
    12181 aatatagcgt gggtcaaaat ctatatctaa ctttctattc agaaaataga gaagatttaa
    12241 caggagactc actagatatt atttcattga ttcaaaatcg ttcgattcgt tttcagagaa
    12301 tggatcccaa tcatttaaaa ctagagaacc aagatcgcta tatcgatcaa ttggtattta
    12361 cgtttagacg attattgaag agtgattgtc atggctaaaa atagttggga gctaaaaata
    12421 aatggacatg atgaacttct tgtgcggatg gaacgctatt caagcgagag cgaacgactg
    12481 attaacgaag cattgaaatc aaaaggttcg gctattgcag tggataggat tacagaaaaa
    12541 attcctgttt ctgaagcaga tttaagaaga gggcaccaac acgcaaaaaa tagtcgtcca
    12601 cttaagactc aatacattaa tttgggtttc atcattagac ctacaagaaa atttgagtat
    12661 ttaaaatatc ctgatttggg gataggtact tctaaaagaa atcagccgga cgaatttatg
    12721 agaagaggat taggtcttgc acttgatcca attacagaac ttctgattcg tcaattcgat
    12781 aaattaaata aataggggga acaacaatgg ctaaaacaaa aactgtagta acaacgttcg
    12841 ataacgtaag tatcaaacga attgctttta attttaagaa cgcaggaaat gcaatcgcaa
    12901 cgaattgtaa tggacaatta gatggcgaaa cagaaatgca aacggtggtt aaaaaatgtg
    12961 gagcgacaga agtaaaatca aaatctaaac caatcaatat gacggtaaca attactgcac
    13021 atgtaccgat ggaagtttat cgacgtttca atgggttgaa acaagatgga cgtattaaac
    13081 caggcattta ctcttacggt cctgattccg taggcgaaga tttctcactt gctgcagaga
    13141 tcgtggatga cttcgaagaa aatagaaagt tagttggtat gttagcatgc acttcgaata
    13201 caggattaac attctctatt gaaaatggtg cggatgaagt agctgcgtta gaactagaaa
    13261 caaaagttat gcaagatgaa tttggtaaat tttatcatga agcaattgtt gcagaacttg
    13321 aagaagactt aacagatcaa tggatgacga atctatctgc tgatgtgatt aaaaaaactt
    13381 cagttgtgac aactacggcc actcaatcac agtaaaaaaa acggaggtag cgaaatgaac
    13441 gaagattact caaaaattga actaaacgat ggaacaattt tgaatttaga acctaaactg
    13501 aatatcaaga aattattgat gatcaataga gattttaaca cagacgagtt tgcaaaaatg
    13561 actgtgggaa aaggatccat ggatatttct gttattcaag gtgcaaaggc tgtgtatatt
    13621 gcttaccgcc aagcgaacat gactgattat atttcattcg atgaatttat cgataaatgg
    13681 gattttgata tggctactgc cagctatatt tatcaattga tgatgttcaa acaagcacgc
    13741 gatgcttatc aaaaagaatt tgaaaaagca aataaggaaa aaaagcttca aaagtaaaaa
    13801 tgccaaagct cttagttgaa acgtgggtcg atgtctattc gatgttgacc gacgtttttt
    13861 ctatgccttc agatttggtt ttaagcgata tctgtttaga tgacattttg caaatggctt
    13921 acaacaagag tgcttatgaa ggatggaaaa actatgcaat aaaccaatct cagaaaaact
    13981 aaagaaagga ggtaaaaaat ggctaaaaag agaacagaag cagaagtaac tttcatagct
    14041 aacgatgacg gattgaaatc tacgttaaaa gaaatcagtg ctgaattaac taaaaataga
    14101 gcagaattaa aactagaaca agctcaatta caacagactg gttctgaatc agacaagtta
    14161 ggaagtaaat tatcttcttt agaaaagcag tatgaattac aaagccaaaa agttgaagta
    14221 actagccaac gtttagccaa tgccaaaaaa tattatggag aaaattccac cgaagttcag
    14281 aaacttgaga gagaactgat taaccaacaa acagcgcaac aacgtttgtc aaacgaaatt
    14341 gataaaacga gtaatacact agctcaagca aaaggcgaaa tacagacgta cgagtctaca
    14401 atgcaacagt tggatagtga acaaaaaaat gttcaagcta gtgcttctct gattgaatcc
    14461 gaatacaaaa aatggcaagt aactgctggt caatcagctt ctgaatccga gaaattagcg
    14521 aaagcccaag aatatgtttc tcaacaatct gaaaatgcag agaaaacgat agatatcctg
    14581 agacgacagt tagaagctac acagtctgag tttggcgcta catccacaga agcaatgcag
    14641 atggaggcga agcttaatga tgctgaacgt gaatttgaag agttaggaca agctgctaaa
    14701 aatgtagata caactaactt ggacgatatc ggaagcaaaa tagatatgaa taatttaatg
    14761 gaagcttctg acgttttaag cgacattggc gataagctta cagaattagg gaaacaagca
    14821 gtggactctg ctaacagtgt aggtagttcc cagagtaaaa tacaagctaa ttttggtttg
    14881 actaaacaag aggctgaaga attaacgaat gtagccagag acatttatta taaaggtttt
    14941 ggagaatcgt tagatcagtc cacagatgca ttgattttgg taaagcgtaa tttaggcgat
    15001 ttaaataatc aagatttaca aaatattacg gaacaagcta tggtcctaga aaacaccatg
    15061 ggcgctgata tggatgaaac gttacgtggt gtaaatggct taatggtcaa cttcggattg
    15121 agcgctcaag atgcaatgga tttaatggtt tcgggtactc aaaacggttt agataaaacg
    15181 cacgaattag gcgacaatat ggcagaatat agccaattat ggagtcaaat gggatattca
    15241 gctgatgaaa cgttcggaat gcttcaaaat ggtttagatg cgggtgctta taaccttgat
    15301 aaagtcaatg acttagttaa ggaaatggga atatcgttaa cagatggtcg atttgagcaa
    15361 aacatggata tgtttagtga aagtactaga aaagcttttg aagagtggaa aaatggtgga
    15421 ggaacacaaa aagacgttat taattccatg attcaagatt ttagcaatat ggatggtcaa
    15481 tacgaccaat taaataaagc ttctacaatt tggtctgcac ttggcgaaga taacgcgatg
    15541 aaagttgtcc aatctttgac tgatgttaac catacatttg atgatgttag tggatctgca
    15601 caaaaaatga atgaagattc tactactccg ttacaagaat taaacggaaa aatagctgaa
    15661 ttaaaggatt cattagctcc tataggcaac acaatcatag atgcactcga accagtaatt
    15721 gattttctag gaaagatggc tgatgcgttt aataatcttc cacaaccagt acaggattat
    15781 gccgtagcga ttggcggatt gactgctgca tttactttat taatgccaat aatagttggc
    15841 ttcatggctc taggtggtcc tactacatta ataataggag cagttattac tgctattgct
    15901 ggagttatag caattataaa aaactggggc gcaattactg actggtttaa gggaatatgg
    15961 agtaaattca ctgattggtt gggtggtact tgggaaagca taaaagaagg tgcctcatca
    16021 gtttgggatg gagtcaaaga aacctggtct ggatttgtag attgggttca agaaatttgg
    16081 caaggagttt ctgattggtt tggagagtta tggagcggat tagttgaagg agcttccaac
    16141 atctggcaag gagtccaaga gacttggcaa gcattcgttg attgggtttc aaatatttgg
    16201 aacggagtca aagaagtatg gtcgattatt tgggcagaca ttgtaggaat tgttcaaata
    16261 ccatggacat taataacgtc attgattcaa gctggtatta atattatcgt gggtatcttt
    16321 gatgtagctg gacagttatt aggcgcagct tggcaagctg tttggacacc tatttctgat
    16381 ttccttaaaa atacttggga tactatgaca caatggataa gcatcgcttg gaatggaatt
    16441 gtaactacat tccatactat atttgatcca gtagtggcat ggtggaatgg tatatggaca
    16501 tctattagta ctacggcttc aaatatttgg aactcaatta gtgcaacagc ttctagtatt
    16561 tggaatagta tcaagaatac aatcactagc ttggtacaag cagctgctac agtaattcaa
    16621 aatatttggt caactgtatc tagttggtta ggtggaattt ggaattcaat cagctctaca
    16681 gcatcaaata tctggagtag cgtgactagt agtataagca atgctataaa cgcagctaaa
    16741 agtgccattc aaagtgtttg gaatagtata tcttcgtgga tcagcggaat ttggaacggt
    16801 atcaaaaaca ctgctttgaa tctttggaat ggaattacaa gcactattag ctctaaagta
    16861 aacgatggaa aaaatgcaat ttcaagcggt tggtccaatc taacaggtat tgtttccgac
    16921 atattcaata atgttaaaag cacgatagct aatatatggg aaggtatcaa aaagactgtt
    16981 agcgctccga ttgattggat tagagataaa atcagtagtg tctttgataa tttgaatatt
    17041 tctataccac atattccgtt accacatttt aaattgagcg gagaattcaa tccattgaag
    17101 gggaaaatcc caacattggg tgttgattgg tatgcgaaag gtagtgtgtt taattctcca
    17161 aatattatcg gtgtaggtga atcaggacct gaagcagttt tacctttgaa aagatctgtg
    17221 ctgcaagaaa ttggtgatcg tatcttgagt agcacctcag tttcatctag gacacaagcg
    17281 gttcaacctg tgaacaatta cgaattcaat ttcacaattg atggtaacgc agatgaagtc
    17341 actatgaagc aaacaactca acaaatcatt gatagcatta caaaagttca aaatgataat
    17401 gcttcggcat ggcgttaaac aggagagtat ttctcctgtt tttttagtat taaaaaggat
    17461 gtgaaaaaat gactgattgt atacattcta taatcgatgg atttcctgat tatttgcata
    17521 aattggcttt agctgaaaga ccaaccatac cttctccaaa aagacagaga gttgaaactt
    17581 ctgttttagg aaggttaggt ggcttagtgc aagattactc gtttgaagac atgtcgttta
    17641 cattgcacta taactattta gaggatgtgg aagaccatca agcgttcaag caatcgtttt
    17701 atatcatgcg tcattggtta aactatgcaa agaaattaga attctctgac gatcccaacg
    17761 tctattacgt tatccagact atcgatattg gggatgcaga aaacgatatt gttgaatggg
    17821 gagagttcga tgtaaatatt actgcgaaac cattcgcaag agttcaagaa gatgtaccta
    17881 taaccgtaga taaaccacag tcatttaact tgctgaataa tagtttagaa gaaagttttc
    17941 caaagattat catcactcct tcagctactt catgccagtt catcttaaat gattatgtgt
    18001 ttagtttcga aggcttagta gcaggaactg atgtagtcat tgatagtgat ttgatgcttt
    18061 gctacgaaga gcaatcggac ggagatattt tagatcggtc caacaaaatg aagaccatgc
    18121 aatatccgac attgcaagtg gatatcaatc attttaattg cactggtttg agcaaaatac
    18181 aaatttatcg taacgggtta aggtaggtga aatagatgat cgataattta ataactattt
    18241 acgataaaaa tgacgcgaat aatttagctg aacatttata tgatacgcaa ggtttaggcg
    18301 ctttgtcaga ctggttaaca gctactgtta gcaataaact aaacggagcc gagatatttc
    18361 agggtactta tccaataagc ggaactaatg cagatttgat tgtagaagga cgtattattc
    18421 agtgttatgt agatgaaaat cgagcaaaac agcgtctacg gatttattat gcaaaaactt
    18481 ctgtaatagg caatacgata gaagtaaaag ctgaacctat tttcaatgat ataagaaaat
    18541 cggtgttgaa taaatatgac agcggaacag aaaaaatcac tgctactcag gcatggcaaa
    18601 acgcaaaagc tttagcgaaa ccagctatcc cttcgcagtt ttctttctcg tcattagtag
    18661 atacgcttgc taatgtgaag atagaaaaag cgaatttttt agaattcttt ggtggaaaag
    18721 agggatctat tctagatcga tttcatgggg aatttcttaa agataataac acattacatc
    18781 atgaaaaaag gctaggtacg gatcataaaa tcaaagcgat ttatactaaa aatttaactg
    18841 gtcttgactt agagatagat gctcaaagcg ttttagttgg agtttatcca ttcattagca
    18901 gttcttcaga aggagaagac gagatcactc taccagaaga agtcattttc acggattacg
    18961 tggatgatta tcctgctgga tatgtttctt ttgttgattt taaagacaaa gcgactgatg
    19021 tagccacatt aagggaagct gctaaagact ggttgaaaac aaacatagat aaacaaaaac
    19081 cacaagtgag tggttcgatt gaattagtac cattgaggca tcaaagaggc tatgaaaaat
    19141 ttgttgatct agaaaaagtt tcgatgggtg acggagtaga tgtgtatcat ccacagttaa
    19201 aagtgaatat gtcagcgaga attgtggaat atacgtttaa tgttctaacc aattcatacg
    19261 ataaattagt tgtaggaaac gtcaaaacaa acttcttaga aaacacagag aataatgtaa
    19321 gcaatttgat taatgatgcc attgatcaat tgaaaaatgg tggcgaaatc agtgatttaa
    19381 tcaatgatat tgtagatcat caaactgata tgattactgg tcaaaatggt ggttatgttt
    19441 tattagatcc taaagaagcg cctagtcgta ttttgattat ggacacacca gataagaata
    19501 ccgcaaggaa tgttttacaa atcaacaatg ctggtattgg tttttctaaa actggcatta
    19561 atggaacata tgaaaccgca tggacattag atggcggatt caatgcctcg tttattacgg
    19621 ctggtgaaat agtaggaatt actattagag gtactacatt aattagtgat ggcactgatt
    19681 atagaacaag tattgctaat ggcaaaatga cttggtactc aaaaaaagtt aacaaagata
    19741 ttatggagct agaagcacgt gattatgtaa gtgctgatgc cggtattgta tcatacacca
    19801 tgaaaactgg tggtggtttc atgattagaa atccacaggg taacttggtt tttagtacgt
    19861 gggataatgg taataacaga ccgtttctat cttttggtgc gcccaatttc aggtatagca
    19921 atgctagtta tgtaacttct ggcgacggta gttctttaag cattaatggt agtgcgggta
    19981 actcatggga atttaaggta gctggtagga ctatgaaatt tactagtgat ggtatgctaa
    20041 cgttgccagg ttgttttttt ggttcatggg aagatgggaa acttgctagg tttgaacaat
    20101 caacggtaca agtatataaa gattttactg ttagaggtac taaaaactca accgtaccaa
    20161 cagaacatta tggacaacga ctattaaacg cttatgaaac tccagaatat tatttcgctg
    20221 attatgggga agccgttaca ggtgatgatg gtaaagttcg tgttgatatt gaccccatgt
    20281 ttgctgagac agtaaatcta agtcgatata tgacacatgt gacacctaca gaactagttt
    20341 tgtgtgctgt tactcatgaa gatattgacc atttcatcat tgaaactagt aagccaaacg
    20401 tattagttag atggaattta gtggcacacc gtctagggta tgaagatatt agattaaaag
    20461 aggatacagc atatgatagc acagtgcttg accaaaaacg tttttaaaac gaagacaagg
    20521 aggtatataa atggctagca gtttatataa tttggctcta gatttcagca aagaattaaa
    20581 ctacaccaaa gctattatgg ctcgtcaagg tgataaaggg attacagtga ctgttaaacc
    20641 atttttaaat ggcttgcaga tggatacgag tggcggaaca tttactttaa aaggaacaac
    20701 gccatctaac cgttacgtag atagtgtggc aactagtgta actagtgaag aagtcacgtt
    20761 ttctcttgat ggcacattta tgagtgaagc aggatattat aaacactgct acgtagaata
    20821 tagaaaagac aatcaaattt taacaacgca agatatcatt tttttctcac taggagtgtc
    20881 tgacatttcg caaggccaag ccgatgaata cgtttcgcaa ttggaagagt tgattcaaaa
    20941 gtataacgaa acttttgatg cttttatggc tgaaatcgaa ggtagagtgg acagcttaaa
    21001 taaacagatt actgatttaa ctggtcaagc taaaacacta caagacaagt tagacgctct
    21061 gaaagaagaa atttctaaat taggtaactt gcaggtgatg tacagtaaca gcatcga
//
LOCUS       DARBDN010000043        21068 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000043 DARBDN010000000
VERSION     DARBDN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.043"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            46..1212
                     /locus_tag="SCH06_001543"
     CDS             46..1212
                     /locus_tag="SCH06_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEG1078124.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            1442..2089
                     /locus_tag="SCH06_001544"
     CDS             1442..2089
                     /locus_tag="SCH06_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEG1078125.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            2173..3117
                     /locus_tag="SCH06_001545"
     CDS             2173..3117
                     /locus_tag="SCH06_001545"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEG1078126.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            3252..4703
                     /locus_tag="SCH06_001546"
     CDS             3252..4703
                     /locus_tag="SCH06_001546"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEG1078127.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            4724..5560
                     /locus_tag="SCH06_001547"
     CDS             4724..5560
                     /locus_tag="SCH06_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEG1078128.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            5560..6219
                     /locus_tag="SCH06_001548"
     CDS             5560..6219
                     /locus_tag="SCH06_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEG1078129.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            6345..7034
                     /locus_tag="SCH06_001549"
     CDS             6345..7034
                     /locus_tag="SCH06_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078130.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            7040..7996
                     /locus_tag="SCH06_001550"
     CDS             7040..7996
                     /locus_tag="SCH06_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HEG1078131.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            8040..8552
                     /locus_tag="SCH06_001551"
     CDS             8040..8552
                     /locus_tag="SCH06_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078132.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(8808..9356)
                     /locus_tag="SCH06_001552"
     CDS             complement(8808..9356)
                     /locus_tag="SCH06_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1078133.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(9445..10626)
                     /locus_tag="SCH06_001553"
     CDS             complement(9445..10626)
                     /locus_tag="SCH06_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEG1078134.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(10862..12370)
                     /locus_tag="SCH06_001554"
     CDS             complement(10862..12370)
                     /locus_tag="SCH06_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEG1078135.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            12529..12720
                     /locus_tag="SCH06_001555"
     CDS             12529..12720
                     /locus_tag="SCH06_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078136.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            12923..13840
                     /locus_tag="SCH06_001556"
     CDS             12923..13840
                     /locus_tag="SCH06_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HEG1078137.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            13833..14906
                     /locus_tag="SCH06_001557"
     CDS             13833..14906
                     /locus_tag="SCH06_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078138.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            15054..15572
                     /locus_tag="SCH06_001558"
     CDS             15054..15572
                     /locus_tag="SCH06_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078139.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            15553..15945
                     /locus_tag="SCH06_001559"
     CDS             15553..15945
                     /locus_tag="SCH06_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEG1078140.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            16021..16956
                     /locus_tag="SCH06_001560"
     CDS             16021..16956
                     /locus_tag="SCH06_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEG1078141.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            17089..17868
                     /locus_tag="SCH06_001561"
     CDS             17089..17868
                     /locus_tag="SCH06_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEG1078142.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            17861..18178
                     /locus_tag="SCH06_001562"
     CDS             17861..18178
                     /locus_tag="SCH06_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEG1078143.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            18422..20032
                     /locus_tag="SCH06_001563"
     CDS             18422..20032
                     /locus_tag="SCH06_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEG1078144.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            20189..21037
                     /locus_tag="SCH06_001564"
     CDS             20189..21037
                     /locus_tag="SCH06_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEG1078145.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         6851 a         3746 c         4216 g         6255 t
ORIGIN      
        1 ttttagtatt aacgtaatag ggtagttttt ttaaggagga aaatcatgtt agagaaaact
       61 ttatacaatc aattattttc acgttctttc tcgctccctg tcgaagtaaa ttattgggac
      121 ggtacaacga aacaatacgg agatacggac actcctcccc aaatcaaaat caatatccat
      181 gaagaaatcc caatgaaaga gattacaagt aacgcatctt tggcactagg agaagcctat
      241 atggatcatc gaatcgagat cgagggaagt atccaagcat tgatcaacga tgcttatcag
      301 caagcaaaca gctttttacg aggaaaagat tatctaaaat ggctgccaaa gaaagaaaaa
      361 catacgaaac aaaaaaacaa agaagatatc catgcgcatt atgacttagg taacgacttt
      421 tataaacttt ggctagatcc aactttgact tattcttgtg cttatttcaa tacacctgaa
      481 gatacgttgg aacaagcaca aatcaataaa gtccatcata tcttagacaa actctttatc
      541 aaagaaggcg aaacgttgct tgatatcggt tgtggctggg gaacattgat gttcactgct
      601 accaaagagt ataatgtcaa ggcaactggg atcacactaa gtgaagaaca atacgatttg
      661 attaccaaaa gaataaaaga agaacattta gaagataaat gccgtgtatt attaatggat
      721 taccgcgaac taaaaggcga aacgtttgat catatcacaa gtgtaggtat gttcgaacat
      781 gtaggttctg aaaatcttga aggttatttc aaagtggtaa aagatttatt gaaaccaaaa
      841 ggaacagctt tgatccatgg aatcagccga caacaaggcg gtgcgacaaa tgcttggatc
      901 aataaatata ttttccctgg cggttatgtc cctggtgtta ctgaattagt tgataatatt
      961 acaaaaaacg atttgcaact gattgatttg gaaagcttac gtcgtgacta ccaattgaca
     1021 ttagaacatt ggacaaagaa ttttcatcaa gtccaagatc aagtcacgaa agaaatgggt
     1081 gattccttct atcgaatgtg ggatctatat ttacaagctt gtgcagcttc atttgaatca
     1141 agtaatatcg atgtgattca atatttgctt gttcaacctg gaaacaatga catcccaatg
     1201 catcgtgcat aattgaggca aaagtactgt ttaaagacta tttaaaaaga agctaagttt
     1261 tatgatgctc cagaagtgaa cttttttgtc taacttctag gattgtctct aaagcttagt
     1321 ttctttttct ttatattttc ataataaaag tttggttctt taatttttaa acatgacaga
     1381 aaattttttc ttcgttatac ttgtaataga atactatttt ataacaaagg ggatcgaatc
     1441 aatgaaaaaa actgttattt atactagttt atttgcagct ttgtttttag ctgcttgtca
     1501 atcaaatacc aatcaaggca catctgggaa tacgtcttcc agtagcgaac agcgctcttc
     1561 acaggtatcg gactcctcaa caaaagcaag cacatcttcg tctagccaga caaaaagttc
     1621 tagtgaagca agtactcagt cagatatcaa agtgtctgca gctcgtgcga tcgaattgtt
     1681 ccaagataaa tacccagata ctgcaattac tagtttggaa ttagatagtg attggggatc
     1741 ttacttctac aagatagaag gtgtcgatga tcaaaaagaa tacgaagcaa gaattgatgc
     1801 tcaaaatgaa aaaatggaga cagagaatcc agaaactcta gatcgagatg aacaaaatgg
     1861 tcaaaagaaa aaagaagatg gtctggatgt tgataaattg atcacgattg aggaagcagc
     1921 aaaaatcgcc gtcgacaaag taggaagcgg tacggcaaca gattgggatt tggataaaga
     1981 tttaggtact acttattggg aagtcaaagt aaaagacggc aatcaaagta catcagtcaa
     2041 gatcaatagc caaacaggcg aagtactgtc aactgaacaa gatgattaag aatttcttcg
     2101 gaaaacaaga gttgattttt cttttagtca tgatacacta gacaaaataa cttgtttgaa
     2161 ggagcgattt acttgagttt agaaacgacc tttgccaatc atatctttgc caatcctttg
     2221 atgaatgcat ctggtgtcca ctgcatgact acccaggaat tagatgaact ggctcattca
     2281 gaagcaggag catttatcac taagagctgt acgatcaatg aacgaaaagg aaatcccgaa
     2341 ccacgctatt ttgatgttcc tttagggagt atcaattcta tgggacttcc aaacttaggt
     2401 ttttcttatt atctagagta tgctcttgcg tatgaaaaag tgcaggaaaa ccaaaatcaa
     2461 ccgttatttt tttccattgc cgggatgagt gtccaggaaa acttggaaat gcttgagaaa
     2521 atagaaaaaa gtgggtttaa tgggatcact gaattaaatt tatcttgtcc caatgtgcct
     2581 ggaaaaccac aactagctta cgattttgag gccacttatg aaacactgaa agaagtattc
     2641 agcatctttt ctaagccgct aggaatcaaa ttgcctcctt attttgattt tgctcatttt
     2701 gatcagatgg ctgatatctt gaatcagttt ccattgacct atgtcaatgc tatcaacagt
     2761 gtgggcaatg gtttgtatat cgatacagaa caagaagcag tagtcatcaa accaaaagaa
     2821 gggttcggcg gcattggcgg agagtatatc aagccgactg ctttggcgaa tgttcgcgct
     2881 ttttatacac gtttgaaacc agaaatccaa atcattggta caggtgggat tcggacagga
     2941 caagatgcat ttgaacatct gctatgtggc gcaagcatgt tacagattgg taccgagctt
     3001 cataaagaag ggccggaaat tttttctaga atcataaaag aattaacgca gattatgtca
     3061 gaaaaaggat atacgtcaat tgacgaattt aaaggcaaat tacgcaccat ttcatagcaa
     3121 agagacgaag gtcatgattg atcttcgtct ttttttataa aaaacactcg tctgttcatt
     3181 cctgtgcaag cgtactcatt gtatgttaga cgaacttgtg ggaaaataac agaggcaaaa
     3241 aggaggataa tatgaatgat gcaacagaat tagcaaaaga gcttaaagaa aaagaattta
     3301 gttttcaaga actagttacg gatatacaga aaaaaataaa gaagcaaaat catgaattga
     3361 atgcgtttgt cgcgcttgaa ccattcgaga gtaattccca cgagctattg attccccagt
     3421 cagaaaaagg gccattggct ggtatcccat ttcctttaaa aatgctcggt caagaaaaaa
     3481 agggatggct agctacttca ggatctcgtt tatttgaaac acaccgagct tctcatacat
     3541 ctaattatgt gcggcaagca gaagcgatag gtctagttcc ttttggacaa accaatgcgc
     3601 cagagtttgg tttcaaaaat attacagacc cagtcatcta tggcccagca agaaaccctt
     3661 ggaaccttga atgtacaccg ggcggatcaa gtggaggagc tgctgctgca gtttcatcag
     3721 gaatcgttcc tttagctggt gctagtgatg gcggtggttc tattagaata cccgcttcgt
     3781 tttgcggatt gattgggctg aaaccttcgc gagggacgat gccagttggt ccatatgctt
     3841 ggagaggatg gcaaggagct gctattgatt tcggcttgac agtttctatg agagacacgg
     3901 aggctttatt ttatgggatg agaagtatcc attccggtgc gccatatcaa gtatcgccag
     3961 ttgagtggca aacacatcca agaaaaaaac ggttgaagat agctttttgt gttgattcac
     4021 cgatccactc acagattagt gaagaggcag tacttgctgt aaaaaaagct gtagatttcc
     4081 ttggaaaaga agggcatgat ttgacagaga ttccttaccc actagatggt cgtaaactga
     4141 tcacgtctta ttatcagatg aatggcgcag aaacagcagc aatgatccgc tcgattgaaa
     4201 caggcatcca gcgagctgtc agaaaagaag aacttgaacc catttcttgg actttgttcc
     4261 aatatggtca gaagctctct gccgctactt acatcgattc tctgcatgta tgggatgaag
     4321 cagcaattgt catggaaaac ctacatcaag aatacgatct attcctttca ccaacgactg
     4381 catttaccgc ccctaaaatc agcgaagatt tgcaaagtga tgcgataaga gcacagatgg
     4441 aacacatcag tgattgttct gaagtagaag gtttagacgt tgtttcttcc atgtttgagg
     4501 agagcttgaa gatcacacct tatacacagt tggctaatct gactggacaa ccagcaatca
     4561 gcttgcctac tcatttgaca aaagaaaaca tgcctctagg aatccaattt atggctgcca
     4621 gaggaagaga agatttgcta tttcaaatcg gctatctatt tgaagcaaat catcagttcc
     4681 atttaccaaa tccatggaaa tagcagaaac aaggagaaga agaatgaaga aaaaaagatt
     4741 gtttgctcta ataactagtg ccttttttat tttaagcgct tgcggtacag ctgccgctaa
     4801 tcaggaagat aacagctgga gtaatgtaga aaaaaagaaa gaattagtag tagcgacttc
     4861 tggcacactg tttcccgcat cttattataa tgatcaaaat gaattagttg gttatgatgt
     4921 agatttggca aaagaggtgg ctaaacggtt aaatgtcaaa atctccttta aagaatacaa
     4981 cgtggatgga caaatcactt ctgtttcaaa aagagaatca gattttgctg cgaacgattt
     5041 tggtatcaca aaagaaagag aaaaaaaatt ctccctttca gagactttca aatattcatt
     5101 tgacagtatg atcgtacgaa aaaaagatga ttcaggaatc cactcacttg aagatcttaa
     5161 agggaaaaaa gcagctggcg aacccaatac tagctatatg cgtttagcgg aaaaacacgg
     5221 agctaaatta gtcacatatg acaatgccac gaatgatcag tatttaagcg atgtagcaaa
     5281 tggtcgaaca gatgttattc taaatgatta ttatctgcag aaaatggccg tatctgcttt
     5341 accagatatc cctgtaaaaa tactggagaa cgtttatttc aatgaaaacg aaagtggttt
     5401 tttattgaaa gaaggaaatg atgctctgaa aaagaaaatc gatggcgtat taaaagagat
     5461 gaaagaagat gggacgacaa agaaaatatc tgaaaaatat tttcaaactg atgtttcagt
     5521 caaaccgaaa gaaacgatgg ctgagtcggt gagtgagtga tgtactttcc cctaattgat
     5581 ttttccctca tgtggacttc acttcctttc gtactgcaag gcttggtata cacattaggg
     5641 attggcttcg tgtcgtttct tttaggaaat ttggtagggt tgcttttgac agttttaggt
     5701 cttttggatt ggctgcctct gaatgtattt attcgttttt atttatcgtt ctttagaggc
     5761 attcccgcac tagtcctgct gtttctgtta tatttcgggt taccttatca attaagtgcc
     5821 ttaacggctt cagtcatctg ctttacgatt accagcagtg catttattgg tgaaatctat
     5881 cgaggatcac tagcaggcgt ttcttcaggt cagtgggacg ctggtttagc ttctggtttt
     5941 tctttctttg gggtattgaa atatatcgtt ttgccgcaag cttttcgaat ctcagtaccg
     6001 gcactcagta acgtagctat ggatctagtg aaaggtactt cgttagcagc aacaatcaca
     6061 gtgccagaaa tatttcaaaa agcaaagatc ataggcggtc ggacattcga ttatttttct
     6121 ctctatattt tagttgcact gatttattgg gtcatttgta tcgggatcga aaaagtgcaa
     6181 cagtatttag aaaaacgttc tatccatcag tcaatctgaa aaatagaaat ggtgctagcg
     6241 tggctggcac catttctatt ttttgtttct tgtatattct gcctagtatt ttaaaaccat
     6301 ttcatgtaaa atgtaaatcg aaaatatgtt cggaggtaga aaacatgaag accccgctaa
     6361 ccatcgaaat agaatcctcg ttataccaat attgcatcga gcaaggcggc ttggttgtag
     6421 aagaagtcac gatgcctgat gaccaaggaa ttgtagatac gcttagctgc ttgacaaaat
     6481 ttgatggaag ccgagaatgg cgatgctatg agctgaaagt gacaaaagca gattttcgct
     6541 ctacagccaa actgtcattt gttggacatt ataattattt tgttttacca agtaaactat
     6601 atgaagaagt aaaaactgaa atccctacag gaataggtgt tttagtgtat cgtccgtaca
     6661 cggttgaaga ggagatgcct gcctctggta catttctgat tgcgaaaaaa gcagcaaaga
     6721 aagagcttgc tgtaccggaa gaagctttga caaaccgctt catggcttct ttattcaggg
     6781 aagtaagaaa agcaaagcaa atggagcgag gcgtaaaata ttttccaaaa gatcaattgt
     6841 acaaagaatt gaaaagacgt tcagaaaatc aagatccatt ttctaacgaa cgatattatg
     6901 aacggttttt agaggaaata gctagtcagg caatcaatga gttgcaagaa gaagttatcg
     6961 cgcttcagca tgattatgaa tatttgaggc aacaacagca gatccgtcgg ttgcctacag
     7021 agccattgga gtgaaaaata tgtactatcc ttatttaaga ggaaaacaat ttgacctatt
     7081 agcattaaaa gaagcactgt cgcgaggatt gctctccaat aaaatccaac cagtgatcga
     7141 accagtacgt gattccgcta cgcttaaaaa tgtgatcgaa ttatttcaaa aaaagcacca
     7201 tccaatcgct gtgatccaaa atccccaagt aggacaattc aaattattcg atcagcatgt
     7261 gcacagttgg acagtcaaag aaaatagctc tgtcgtccct gcacagatct taacgccaga
     7321 aaatctcagt gaagtactgg attcacctcc agcgtttctt gttttcgatg gacagcacta
     7381 cccaaaagat acagaggtgt ggaaacagtt ggcaggagtt gattcgaaat ttttgatacc
     7441 agatactagt cgctttcgca tctggctgcc cgaaaacaaa attgtgatcc gtgactcttt
     7501 tcaaacgaga aagcatgttg aaagttatgc agataaaaca gatgactttt ttagtgatga
     7561 ctatcttttt ttccacgcag acggatatat tggattttct gatttcacga tcgaaggtag
     7621 ccgttatttc gataaagggt tccctagccg agcgcttgct atccatctaa cgtatattga
     7681 tgcttacggc aatatacgcg tgaaacattt tgtctctgac agtaacgact ctgctaaaga
     7741 ccaagcattg aagtttcttg aagcaggaga taaaatgaaa aaatggatca tgcgtcacca
     7801 tcatcaactc ttgattactt caggaatgat tgaattattg gctctttacc agcaacaaaa
     7861 attccctgga ctgggagtgt tgaaaaagtg gtcacttatg catcatttgg aacttattag
     7921 tcacctgcta gatcatccaa aagattggct taaatattat tcaaaagttc aggaactata
     7981 tgaagtgatc caatgattag ataatgtaaa tgaaaaagga atagaaaaga ggaaactgga
     8041 tgtatattcg gcaaacaagg aaagaagaag tagaagaagt ggtagaaatc attaatgccg
     8101 cagcggattt cattgcttcg caaggctctc ctcaatggca aaacgggcag aaaccaacaa
     8161 aagaaacgat tttgaacgat attgaaagaa aagaaagcta tgtattaata gtggaagatc
     8221 aaattgctgg aacagctgca ttagtctcag gcgtggatcc cgtttacaca aaaatagatg
     8281 gtagttggaa agaatcaact ggtccttatt tatcgattca tcgtgtcgct ttagcagaaa
     8341 gtactcgagg aaaaaaacta gcaaaaccgt tcttagaaca tttgttgacg attgcagcca
     8401 gcaaaaatat ccaagatatc cgtatcgata cttatccagc taatgaaccg atggaaaaga
     8461 ccatctattc tgctggattc acttatcaag ggatgattga atttcctttt gaacacggcg
     8521 aaagaaaagc atatcaaata atcatcaatt gactataaaa tcatctgagc aaagataaag
     8581 acattaacac tactgaaaaa aacaatcata tgatagccaa gaggttgtaa cagaagtggc
     8641 cagcttcaaa aaacaagaaa gaatttccga aaatgcttct caaatttttg tggaatttta
     8701 gcgtatttta cgaaatagct gctttctgaa actcccttca tcgagaggtc gtgacatagc
     8761 ttttgtcacg atctctcggc ttatcctacg agtattattc gatacattta tatcaataat
     8821 ccttttttta ttttatctgc agcttcttgg aacgctccat cgtttgacac gactaaaagt
     8881 gaggggatag ctttcaaacg tttcaactgt gctaaatctt ctacataaac cgccagtctg
     8941 gctgaaatct gttcagatga atctccacgt tttttcaggc gcgattgcaa tgtttcttta
     9001 gagatcgtaa taaagatagg acggactacc gtcccgaaat actcatataa atgccaaaaa
     9061 ccatttgctg tcaaaacggc gtaacaattt cctactgtca gtttcttttt aatttctgct
     9121 ttactggaac catatttatg ttgagcatat tggtcccact ctgcaaactc atttcccttg
     9181 atcatctgat tgaatgtatt gtcagaaaca aaataataat cctcttgatc tttttcccca
     9241 ggtcttggtg atcgattcgt gtaagtaatg atcttttgtt ccggctgaaa aatagcttct
     9301 gcgagtgaag tttttccaga accagaagga ccgataaata catagcaata attcattgtc
     9361 atttctcctt tgatgattga acaagtgaaa aagctttgga aaatatttcc aaagctttta
     9421 aaagtaactt tgcttttttg tattttatac cagcaagcca gtcacaatag cacttaaaaa
     9481 gctgactaaa gtcgctgtta gcaaaatttt caatccgtgt tttgcgacaa gatttccttt
     9541 ttcttcattt aatcccttca tcgcaccaga aatgatcccg atagaagaga agttggcaaa
     9601 tgaaacgagg aagacagata taattgctgt tgtacgctca gtaaaatgga aattaccatt
     9661 tgctaattct gtcatagcaa caaattcatt tgtaaccagt ttagtcgcca tgatactacc
     9721 ggcatccact gcttctttcc atgggattcc gctgatgaag gcaagagggg caaagatgta
     9781 acctaggatc tcttggaaag tgatgccgaa tatcccgtgg aagatagcat tgatcatggc
     9841 aatcaaagca acaaaaccga taagcatagc agcaaccgtg atcgccacat ggaaaccatc
     9901 aagaatgtat tctcccaaca tttggaaaaa tgtctgttct ttgttttctt caatgatcag
     9961 ctcatcttct ttttcttcta atacataggg atttacaatt gaagccagaa tataaccgcc
    10021 aaataagttc aaaacaaggg cagtgatcac atatttagaa tcgatcagtg ccatataaga
    10081 tccgacgatc gacatagaaa ctgtagacat agccgataca ctcatggtga acaaacgttt
    10141 ctcagatagg aagggtaatt ccttttttat ggaaataaaa acttccgatt gtcctaaaat
    10201 agcagaagct actccattat aagattccaa tttgcccatc ccgttgattt tacttaatcc
    10261 tagaccaaca gctttcataa ataatggaag aatcttgata tagcgtagaa taccgataat
    10321 agcagaaata aatacaattg gcatcaatac ggaaagaaag aaaggtgcac ttcctttatt
    10381 tgctacaccg gcaaaaacaa agtcaacacc ttgcccagca aaagcaagaa gatgatcaaa
    10441 catttttgcc aatacagaaa caaccgctgt accaaaagtt gtacgtaata atacgaaacc
    10501 aagaacaagc tgtaaaacga acatcacaat tagtggtttc aatttgattg cttttttgtt
    10561 actgctgatc aaaaaagcaa gccctaatgt gacaaataaa ccaataatac ctaataaata
    10621 actcaaataa tcactcctat tccaaattcc gttttatttt acctgttttg caaataaaat
    10681 actaatcttt agtgaaattt tcattacttt tttagagtga aacgcattca ttttccatta
    10741 gaaaataaag cgaacaaaat aaaaggttta aaaagtgtaa cgtcttagta aagtctataa
    10801 aaaaacgaaa ctatcgatta agctaatagt ttcgttttca acatttataa gtaaactttt
    10861 tctattggta atatagattt tcggaagggt agacaggtgc gcaggtaata tcgattccta
    10921 gttttttcaa tgtttgttca tcatttttat tgaccatcac agtagagtgg gcttgtgctc
    10981 cctcaagttc agctagttta tcataagcaa cttgagcgat tggattcgtt actgcactga
    11041 ttgataaagc gatcaagact tcattgatgc ttagtgcatc caaagaggaa tgaagtgtct
    11101 ttgatttcaa tccttgtatt gtttcaagaa ctaatggtga caataaagga atgtcatctg
    11161 cgatatgggc taaatgtttt actgcattta agataactgc cgctgacgca tccatcaatg
    11221 aacttgtacg cccggtaatg atgacttcat ctggtaattc gattgcaatc acagcagaag
    11281 gatcttttgt aggactttgc gcttgaatct tatctgcata gtcatgggca gggactacca
    11341 cgtttcggtc ttcaggacgt aaaccgactt cttccataat cagtttgatt cgattaactg
    11401 cttcttcgtc gatcaatcct tttttgaagt cgcattctgt ttggaaataa cgacggatga
    11461 tttcttgttt agaggcttct tggacaacgg tatcatccac gatcccaaat cctacacgat
    11521 tcacacccat gtcagtagga gattgataaa cagattcttt accagtaatt ttttcaataa
    11581 tacgtttgat tacaggaaat gtctcaacat cccgattata gttcacagct actttattgt
    11641 aggcatcaaa gtggaaggaa tcgatcatat tgacatcttt tagatcgact gtggctgctt
    11701 cataagcaat gttcagcgga tgtttcaacg gaacattcca tactgggaaa gtttcgaact
    11761 tggagtaacc agctgcatgt cctttttggc tttcatgata cagttggttc aagcaagtag
    11821 cgagctttcc acttcctggg ccaggagctg tcactacaac gattggttta gttgtttcaa
    11881 tatactcatt ttttccaaaa ccatcttctg agacgatttt ttctacgttg actggatagt
    11941 cttcgatttc tgagtgttta tagaccttga tgtttcgtct ttctagttta ttgataaaga
    12001 ctttcgtggc aggctgtcca ctatagcgag tgataacgac actgttgatt aataagccat
    12061 aaccacgtaa ttcatcgatt aaccgcaaga tatccatatc ataagtaatc ccataatcac
    12121 cacggatctt attacgttca atatctccag catagacgca aatcagtatt tcagcttgat
    12181 ctttcaattt ttgcagcaat ttgattttcg catcttcttc aaatcctgga agtacacgtt
    12241 tcgcatgctt gtcgtcaact aacttcccac caaattctaa atataatttg tcatagtggt
    12301 tcactcgttc caaaatatac gctgactgct cttcaatata tttttctgaa tcaaaaccaa
    12361 tttttttcac taggttccct ccttaagtac taaagcattt tttcattttt ttgaggattc
    12421 gtcaactgga agagcgaaat tcctcaaaaa aacaaagaaa atggtttaaa ccaacttgtc
    12481 tagatagtta ttcattggta tgatagtttt tgataaggaa ggtgctacat gaaaaaaaga
    12541 cagaaaaaga aaaacgcata taaacactat atccgttcga tttttaccgg ttatgaaaga
    12601 atgcttgaag atcccgaatt ggaacaattg acgtttactt atctaaacga agaaacgcag
    12661 ctaactcgtg atgagcatca gcgcattcat ttcacaacaa gagatctgcc tagtaaataa
    12721 aaaataagat aaaggtcatc ggattcgatt ctgtcctatc agatggaaag actagttgat
    12781 cgaaaaaaag gctgtaccaa attttggtgc agcctgtttt atggagcatt gcccgctctt
    12841 ttttataaca attttttaca gaaaatggta ctattgaagt attaataagt gaaaaacaga
    12901 tgagtaagag gaggcaagta gtatgaaaga gccagataca aatgcaaatt atgagccaga
    12961 cgaactagag gagacgaacg cggatcagga tacaggacaa gaatcgtctt ctttttacga
    13021 tatcaaagaa aaagcaagca tgaatctttc ccaattatta gaagacttac aggcttttga
    13081 aaaagctgtc cgcgaagaag atatccctga gatctaccgt ttatacaatg gccgattgaa
    13141 tgaagaatta aaaagaagct caaatgaaaa tcacgagatc gatcaattgc tgatgcgtaa
    13201 gatccatgat cgttttttac aggaatttcc ttttatggaa caagtagaaa acatctcgcc
    13261 aacgatgagc tattacaaaa tcggcactta ttaccatgat cggcccacgg tcggtattga
    13321 tgcaagtctg ccagaaattt ttgttttgcc taagatcgat gaagagtggg agaaatattc
    13381 ccaaccggag tcaacggact atgacaaaaa aatcaatgag ctagacgcaa aggtgatcac
    13441 tgctcagaca gaaattgaac gtttagatga acaaataaaa gaaatcaatc gacaaatgac
    13501 tgatttgaac gacaataaag gattcttgaa tcgtaaaaaa atcgaggaag aaattcaaga
    13561 attagagaag aagaagcaag tactatctaa tgaaaaatta ggctggcttc cttatattga
    13621 gacgcctgaa acaatccagc agcaaaaaga agcattgaag caagaagcaa gagcagacca
    13681 gcttcgtgca gccatcgtag aaaaagaaca aaggcaaatc agacgctatt tcggtagcaa
    13741 agagggattc ggtcaagcaa tccatgaatt cttgatgaat tatcttggca atgagaatcc
    13801 taataatcaa tctaatgaag gaggttccga gtatgaatga acacgatgaa gcagaatgga
    13861 caaaaaatga agaacaaaca gaagatcatg aagaaacgaa cacttcattg gaagaacaaa
    13921 caagtaatcc tctggatgac acagaagaaa tccctatgct agaggaaaca aaaatacatg
    13981 aaaaagaaaa agtaactccg acgaatacga atactgcaga aaacacccat gcttacgaaa
    14041 taactgaaaa tcccgggtat ttagaaggaa aagagcaaga tcatcaagat atcgtcagtt
    14101 tgattgaaac agcggaagca gaattagcgg atttacgtat gagaaaagat ttgatcgaat
    14161 cagattttcc acaattatta gaatcatatg atcgttttat attgaatgaa gaaccaatct
    14221 ccacgatcgg aaagacaagc ctgatcgaat acttcacgta tgaattactg aaaccgttga
    14281 atgatattgg tctggaacgg tcaaattcag cttatgacac atggaaaaca agacattttt
    14341 cgatcaatta tacgttgaat ggacaaaacg aattagtctt ttcctttgta ttaccgacca
    14401 tcgatcaacg ataccaagtg gaatcgatga gtctcctaaa cgtatcacca gagacaatgg
    14461 aaatcaatgt ccaagatgac cgggtgcttt ctttgatccg acactggtca gtggatcgag
    14521 tattctctgc agggcagatc acgatattca atcacaaatt gaatcaatta ttagcccatg
    14581 caagaacact tggttttacc gttaatcaga cattactaga caatacgaag ccacttcgtt
    14641 tgaatcttca gagcgaattt gaattgacga atgaagtatt ggatgatatt tttatcgtgg
    14701 caatgaaaaa tccatcctac gatatggaaa agatcaacga aactacttat caagtacgat
    14761 tagataaagg acagtcttta acgataacaa caaacgaaaa agatcaaaca gtcttgtcga
    14821 tctcatctgg agactaccca cgatctgtca ttgatttctt tatcaattac gaattcttgg
    14881 tcccattaat ggtgagaaag tcctgattgg ataagttgga ttaccagatg tcattcagat
    14941 aattctgttc caaaggactt gcggcagtta tccagaataa ttgtcacaag tcttttctgt
    15001 atgtactaaa tggacgtgaa taacttgctg atgaaggagg gatttcatta ggaatgtcca
    15061 caaataaaat agcacagctt agcttattgt ctgctgcttg tgtagcaggt aggatcgctt
    15121 ttcaatttat tccgaatttc cagccaatga ctgctatttt tttatttata gtactttact
    15181 taagcttaaa agatgcgtta attgtcatga gtctttctat tgcgatcagc agtttttatt
    15241 ttggtgttgg accatgggtc atcggccaat ggatcagcta tactgttgtt ctgagtttgt
    15301 tttcaatcgt ctgcttgaga aaaacagtgc aaaggaatct atggttaaag ggagtctgtt
    15361 tttttctggc gggcatggtt tacggaatag gtatgaccgt ttttgatacg ctgttatatc
    15421 gtttgcctca accttggatc tattaccttc aaggggtgtc gtttgatttg atgcacagta
    15481 taggcaatgt tgtgttcttt cttgtttttc tgccagtcgt caaacgtttt tacaatcatt
    15541 caggaggaaa aaatgaaaaa aataatttat agtttgcttg caatgagtgt cagtatactc
    15601 attttgacaa gttgcagtac aacctataca caatcggctt ccaaccaaaa ggaggaagta
    15661 aaaacatcgc aaaaagcaac aatcacgtta caagaaaatg gtcaaaactt ttcggaaaaa
    15721 gaagtggtct tcaaaaaagg cgatgattta ctgagtattt tgaaacgaaa ttttgaagtc
    15781 aaagaagata acggcttcat cacttcgctt gaagggcact cacaggatga gaaaaatcaa
    15841 ctctattgga tgtttactgt ggacgggaaa agtgctacta ctggtgccaa agagatcaaa
    15901 ttgaatgatg gacaatcggt cattttcaat ttgtctaaac tataagtttc ataaaaaact
    15961 gttaaagggc gaatattgcc ataattcagt gagttcagtt gatgaaagaa ggaaaataac
    16021 atggaaaatt ttaaaaaaag cggaatgttt tccgtaattg ctgctctagg ggctaatatt
    16081 ctagttgcta tcagcaaatt tgtcggctat gcaatcagtg gcagtgccgc catgctaaac
    16141 gaaagcatcc acagtatcgt tgattgcagc aatcagattt tgctgttatt cggtgataaa
    16201 caagccaata aaggacagag cgagttgcat caatttggtg aaggacgagc aaaatacttt
    16261 ttcagtacaa tcgtcgcaat gatgcttttc ttcggcggtg gggcacttgg ggtgatggaa
    16321 gcttttgaaa agttgacgca tccatcccat gaagtgggta atccgatcat tgttatagca
    16381 atactgttat ttggtttggt aatcgaagga agttcgttac gcgtggcaat gaaagaaatc
    16441 aaagaattga atactgaaaa actttccacg atgcgctttt tgcgcgaaag tcgacacagt
    16501 gaaatactga ttatttttac ggaagacttg tgtgctgtaa tcggtttggt cttggcttta
    16561 gcaggaacaa tattgactta tgcaaccggg attgctgcat ttgatgcgat cagcggattg
    16621 ctgatcggtt tcttgctgat gggagccgcc attttcctag caaaagaatt ttatagtctg
    16681 atcatcggtg aaagcgtgac agcaagcgat ttatcaaaaa tcaagttagc ttttgaacgt
    16741 cctgagatca gtcggctgat cgatataaaa acagttcatt taagtccaac ggagatttta
    16801 gttgcagcaa aagcagatat cgttggtaac aaagagaatg aagcttactc ggtcatcaat
    16861 gatattgaaa aaaatatgcg tcagtctctt cctgacaaga agatgtatat atacattgaa
    16921 acagataaat atgacccaaa ttattctcgt aaataaaacg tttattcatg aattgaagca
    16981 aaaatgagaa aaatataatc ttgtttttaa ataaaacggc tacaatttag cgaatttatg
    17041 ttacaatgag tccgctgttt atttgttgta attaaaggag atattttaat gaacaaaaag
    17101 aaaagtgcgc catggcttca agctttgcat gcagtgatgc cactttgtat aagctatata
    17161 ccagtaggat tagcttgcgg agtattgttg caaaaagttg gatttgatcc tctcttatca
    17221 ggactgttat cgattctggt cttttccggt ggcgcgcagt ttttagttgc atctatgctt
    17281 acgacgcaag catcatttgc aacgacatta ttgatggttt tctttttaga attacgctat
    17341 acattattag gagcaagtct tgccggtttt atgaaaaaag aaaagcggac gtttttggct
    17401 gtcttttctc aatcactgaa tgatgaaaac tatgcggtga actacttaaa gttttcaact
    17461 gacccttcct ggaataaaag aaaggcttta tatgtcaatt ggttctcaat gactgcatgg
    17521 gccggtagca atatgatcgg taattttttc ggctcggtga ttcgagtaga tgctgacctt
    17581 gtccattttg ctttgacggc catgttcatt ttcatgttta tcatgcagat gaaaagcgca
    17641 ctactgatct ttacaggttt attctcaggc gtattagggg tcgtattcat ggtattattc
    17701 caaaatactt tcggattgat tgcagcaaca gtcattgctt catttgccgg atttatgctg
    17761 gagaaggcat tcaaaaaaga aaaagctaag aaactaagag accgcggtaa agatgtcaat
    17821 gagccgctct tcaacttccc ggaacaggag gccaatcacc atgactaaac tatatttgct
    17881 acttttagtt gcttgtctgt tcatcgtggc atatatcccg cgcttgttcc cgatgcttta
    17941 ttttactcat cgaaaagtgc catcctggtt cagtgactgg atgaaatatg taccggtggc
    18001 attatttgcg gcgttagctt ttaaagatgt tttcattact catgaacatc tggatattgc
    18061 ttggaatatc aaaatagctg caatgattct agtagcaggc gtggcttaca aaacacgttc
    18121 gatggcgttg tcagttttga caggacttgc gtctgtcttt ttgctgtcta tgctttaaac
    18181 tgttttattt tattaaaaac agagattgcg acataagttg ttcaaactga tctatccgaa
    18241 ctgcatttgc aacagtcaat tctggatgca agtttattcg tagggataaa aaagattagt
    18301 gttggcttat gatgcaagct cttttttatt ttaggaatta gagagggatt tgtccttcta
    18361 tgattttttg ctataatagg gaagatgttt attttatgaa agaatagttg agggaattta
    18421 aatgaataaa aaattgatgc aaggaacatt ttggctaacc tttgctaatc ttctatgtaa
    18481 agttttaggg gtagtctatt tgattccctg gctaagtatg atggggaaca atcaagatgg
    18541 tatgcttgct acgacattgt ataatgttgg ctatcttcct tatggattgt tcctgatgct
    18601 tggtacagtc ggatttccaa atgcgattgc aaaaaaagta gctgtagcca caaaagaagg
    18661 agataacgct gcttgtcggc tgatttttag aagtacgatc aatatcatgt ttgtcatcgg
    18721 tatcgcctct gctgcactga tgtatttatt tgctccttta ctagccggaa tcagtccgat
    18781 tgctaacgtt aataatggga tactagctat cagaagttta tgcccatctt tgattgctat
    18841 cccaattctt agtgcaatga gaggatattt ccaaggaaaa aatgatctgc ggccttatgg
    18901 aacttctttg attatcgaac aggctgtgcg agtgatcgtt atcttggctg gtacttatta
    18961 cttgcgcgta ttgactgacg gaaccatatt agaagctgta ttgatcagta cagtcgcttc
    19021 tttcttcggt gggttagctg cgattatcca tatgtatatc gtcggacgca gaaaagactt
    19081 cttcgaactt aaagattttt tgatttccag ccgttatttc gaaagagaaa accgatctgc
    19141 ctctgtctct atcattcggg aaacactacc gtttattttt gtcggctcag tcattactat
    19201 cgttcaaatg atcgaccaag taacgatgaa accactgctt cactttttcc gtccagagat
    19261 cgcagatcag caactggaat tcttattcag ccgtgcttct gtcaatccaa ataaattgac
    19321 attgatcctg atctccatgg taggaacagt agctataagc agcttgccaa tattaagcac
    19381 gatgaagaaa aaagatcgga tacaaatcga aaaaacagta ggagatagtt tttcgattgc
    19441 gttattgatt cttcttcctt cattgactgg aatgtcttta ttagctggac cactatacac
    19501 attgtttttt ggctatgatc ctgaaagtgt cggatatttc caaatggctt tgctagcttc
    19561 tttgtttttc tctttattca cgatcctatc tacgatgctt caatctttga atcaccatcg
    19621 ttttgcgatc cgattaactg tagaagcaat tatcctgaaa gtcatcttcc aagtaatcgg
    19681 attaggatta gttggcggat acgggatgag cttatcaaat ggcttagcat tcggtattgt
    19741 ctttgttcgc ggctatcact ttatgtgcaa agaataccga atagcacctt tagcaaagat
    19801 cagcaatttt ttcttaaaaa ctttccgctc caccctgatt atgcttgcag tatgttttgc
    19861 cgttttcttt ttgctgaatc agcgattgtc aatggaatca aaaagctatg caatgattta
    19921 ttgtgtggct gtaggaagta ttggcggctt agtattttta ttttctcaat tcggaaaaaa
    19981 tgggtttcga atgttgaaaa atgttaaaca tcatagcaga agcaaagaat aggttaacta
    20041 atcgtttttt gctgtcactt gaaaaacggc aactcgtatg attacgcttg tcgtttttct
    20101 attttccaat tttagtttca tatctaatct tacttatgat atagttataa ggtctggaaa
    20161 aattctttga aacgaggaaa ttaaacacat gaaacttgca gtagttacag atagttcggc
    20221 atatctgccg gaacgtatca agaaccatcc cgacttattc gttattccaa tccctttgat
    20281 tatggatggg aaaatttata acgaaggaat cgatatcgaa gcggatgaat attatggact
    20341 tttaaaaaac agtaaagatt ttcctactac ttcacaacct gtcgtagggg aagttttggg
    20401 tttatatgag gaattgaaag agaaagggta tgacacgatt ttaagtatcc atctttcttc
    20461 agggatttct ggctttgtca acacattatt tgcgatgaaa gatgacatca gcggagtaac
    20521 ggtcattcct tatgactcta agatcactag tatgccgatg ggacacatgg tagaagctgc
    20581 cttagactta aatgatgaag gtcagtccct tgatgaaata cttgcacata tcgatcgaat
    20641 ccgagataat acctatgctt atctgattgt agatgatttg aacaatttag tacgaggagg
    20701 acgtttgaca aatggtgcag cgctgattgg cagcttatta aaaatcaaac cgatcctgac
    20761 attttctgaa gggaaaattg ttttattcga aaaaatccgt tcaagtaaaa aagcatttgc
    20821 tcgagctgaa gaaattattg gtagaagaaa taacgaaata caaccgccag tcaaacttta
    20881 cgtgatacat gcaaataatt tagaagtagc gattgcggag aaagagaaat tgcagaaaaa
    20941 atatccaaat gcagaaatcg aaattggtca tttcggacca gtcattggta cacatttagg
    21001 tgaaaaagcc atcggcattg ccatttcagc gcaataattc cttttattca aaaaacatac
    21061 caaaaata
//
LOCUS       DARBDN010000044        20873 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000044 DARBDN010000000
VERSION     DARBDN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.044"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            99..293
                     /locus_tag="SCH06_001565"
     CDS             99..293
                     /locus_tag="SCH06_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078146.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            562..861
                     /locus_tag="SCH06_001566"
     CDS             562..861
                     /locus_tag="SCH06_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078147.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(958..1392)
                     /locus_tag="SCH06_001567"
     CDS             complement(958..1392)
                     /locus_tag="SCH06_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078148.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1624..2334)
                     /locus_tag="SCH06_001568"
     CDS             complement(1624..2334)
                     /locus_tag="SCH06_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEG1078149.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2324..3184)
                     /locus_tag="SCH06_001569"
     CDS             complement(2324..3184)
                     /locus_tag="SCH06_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEG1078150.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3189..3827)
                     /locus_tag="SCH06_001570"
     CDS             complement(3189..3827)
                     /locus_tag="SCH06_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEG1078151.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3842..4141)
                     /locus_tag="SCH06_001571"
     CDS             complement(3842..4141)
                     /locus_tag="SCH06_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078152.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4184..5668)
                     /locus_tag="SCH06_001572"
     CDS             complement(4184..5668)
                     /locus_tag="SCH06_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEG1078153.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5688..6149)
                     /locus_tag="SCH06_001573"
     CDS             complement(5688..6149)
                     /locus_tag="SCH06_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1078154.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6167..7234)
                     /gene="ulaG"
                     /locus_tag="SCH06_001574"
     CDS             complement(6167..7234)
                     /gene="ulaG"
                     /locus_tag="SCH06_001574"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEG1078155.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7452..8222
                     /locus_tag="SCH06_001575"
     CDS             7452..8222
                     /locus_tag="SCH06_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEG1078156.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8495..9322)
                     /locus_tag="SCH06_001576"
     CDS             complement(8495..9322)
                     /locus_tag="SCH06_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1078157.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9890..11125
                     /locus_tag="SCH06_001577"
     CDS             9890..11125
                     /locus_tag="SCH06_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEG1078158.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12124..12384)
                     /locus_tag="SCH06_001578"
     CDS             complement(12124..12384)
                     /locus_tag="SCH06_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEG1078159.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12411..13712)
                     /locus_tag="SCH06_001579"
     CDS             complement(12411..13712)
                     /locus_tag="SCH06_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078160.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14004..14462)
                     /locus_tag="SCH06_001580"
     CDS             complement(14004..14462)
                     /locus_tag="SCH06_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1078161.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14475..15806)
                     /locus_tag="SCH06_001581"
     CDS             complement(14475..15806)
                     /locus_tag="SCH06_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HEG1078162.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15817..17259)
                     /locus_tag="SCH06_001582"
     CDS             complement(15817..17259)
                     /locus_tag="SCH06_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1078163.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17246..18010)
                     /locus_tag="SCH06_001583"
     CDS             complement(17246..18010)
                     /locus_tag="SCH06_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HEG1078164.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18114..18989)
                     /locus_tag="SCH06_001584"
     CDS             complement(18114..18989)
                     /locus_tag="SCH06_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1078165.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19244..19328)
                     /locus_tag="SCH06_001585"
     tRNA            complement(19244..19328)
                     /locus_tag="SCH06_001585"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19292..19294),aa:Leu,seq:caa)
     gene            complement(19346..19417)
                     /locus_tag="SCH06_001586"
     tRNA            complement(19346..19417)
                     /locus_tag="SCH06_001586"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19383..19385),aa:Gln,seq:ttg)
     gene            complement(19427..19499)
                     /locus_tag="SCH06_001587"
     tRNA            complement(19427..19499)
                     /locus_tag="SCH06_001587"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19464..19466),aa:His,seq:gtg)
     gene            complement(19561..19645)
                     /locus_tag="SCH06_001588"
     tRNA            complement(19561..19645)
                     /locus_tag="SCH06_001588"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19609..19611),aa:Leu,seq:caa)
     gene            complement(19666..19736)
                     /locus_tag="SCH06_001589"
     tRNA            complement(19666..19736)
                     /locus_tag="SCH06_001589"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19702..19704),aa:Cys,seq:gca)
     gene            complement(19782..19853)
                     /locus_tag="SCH06_001590"
     tRNA            complement(19782..19853)
                     /locus_tag="SCH06_001590"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19819..19821),aa:Gln,seq:ttg)
     gene            complement(19865..19937)
                     /locus_tag="SCH06_001591"
     tRNA            complement(19865..19937)
                     /locus_tag="SCH06_001591"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19902..19904),aa:His,seq:gtg)
     gene            complement(19940..20013)
                     /locus_tag="SCH06_001592"
     tRNA            complement(19940..20013)
                     /locus_tag="SCH06_001592"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19979..19981),aa:Trp,seq:cca)
     gene            complement(20020..20100)
                     /locus_tag="SCH06_001593"
     tRNA            complement(20020..20100)
                     /locus_tag="SCH06_001593"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20064..20066),aa:Tyr,seq:gta)
     gene            complement(20102..20177)
                     /locus_tag="SCH06_001594"
     tRNA            complement(20102..20177)
                     /locus_tag="SCH06_001594"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20142..20144),aa:Phe,seq:gaa)
     gene            complement(20213..20285)
                     /locus_tag="SCH06_001595"
     tRNA            complement(20213..20285)
                     /locus_tag="SCH06_001595"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20250..20252),aa:Asp,seq:gtc)
     gene            complement(20295..20367)
                     /locus_tag="SCH06_001596"
     tRNA            complement(20295..20367)
                     /locus_tag="SCH06_001596"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20332..20334),aa:Val,seq:tac)
     gene            complement(20383..20454)
                     /locus_tag="SCH06_001597"
     tRNA            complement(20383..20454)
                     /locus_tag="SCH06_001597"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20419..20421),aa:Glu,seq:ttc)
     gene            complement(20469..20558)
                     /locus_tag="SCH06_001598"
     tRNA            complement(20469..20558)
                     /locus_tag="SCH06_001598"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20522..20524),aa:Ser,seq:gga)
     gene            complement(20598..20671)
                     /locus_tag="SCH06_001599"
     tRNA            complement(20598..20671)
                     /locus_tag="SCH06_001599"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20635..20637),aa:Asn,seq:gtt)
     gene            complement(20681..20796)
                     /gene="rrf"
                     /locus_tag="SCH06_001600"
     rRNA            complement(20681..20796)
                     /gene="rrf"
                     /locus_tag="SCH06_001600"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6573 a         4383 c         3325 g         6592 t
ORIGIN      
        1 tgattctttt tatttatcat aaagatatag atacataatc attttcactt acatatattt
       61 gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta gaagtaaaaa
      121 caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat cctttacttg
      181 gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata aagaacgagc
      241 tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag taaatccaat
      301 gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat tatagaatta
      361 gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata ccatatgatt
      421 atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat gaatcaaata
      481 tacttgtcat tcatcatgaa atatagagac ttataaaatt gtttattttt ataatgtatc
      541 agtatagaaa ggaaataaaa catggattat actgttgaat ttgacagtga actacttaag
      601 caatttccac aagaagaaca tttcatgtat aaagaagcaa tttcccacaa agtgacagag
      661 tatttggagc ataatttttt tcgtataaag ccagtgcgta ctcgttcggc aaaaggaata
      721 tacgagatga aagtcaaaat taataaaaaa aattatcgca tagcatttgc tttaaaaaaa
      781 aatcatgtgt tcatttttta tattagttcg aatttgcaaa aaattgtatt tgataaagag
      841 gtgagtaaaa aaataaaata gctgagcatt ggaggataga ttgagtgata ctaagtctat
      901 cctcttgttt ttctaaagaa ctaagctaga attttttctt ttgtacgtta ttatatgtta
      961 tttgtcatta ccaaaaagca ccttttttct tctagtatct atgacataag aaataccacc
     1021 catttccttt acttgaacaa atcctactga ttcataaaat ttttttgttt tctcagtatc
     1081 atctgtcaat aattcgattt ggactggtcc ataactagtg atcttctcca aagcttcatt
     1141 caaaagcact ttgcctattc cttggcgctg atacctcgga tgaatgagga tatcttgaat
     1201 aaatgcgatc gtcgcaaaat cagtgatcca acgaacgatt ccgataatct tcccttcccc
     1261 attacgcttt atcagagatt cagattgttc aaatgctcta gctaaccttg cagtgtcttt
     1321 tgtgtaattc gtccaaccaa cgctcttata taattcagaa atctcatcga tcataaggga
     1381 atcaatattc atttttttct tcctttctta tacaattctc cctctaataa tacagttctt
     1441 tgactattta atctatcaca tataactctc ctgtaaagat tctctcgatt ccttaaaatt
     1501 cctctttcct tttagaatgc atactttttg ataaataaaa aggttgtgat aaattttctt
     1561 cacaacctct gtttctctct atcaagtgtt atcttttaat tttctaccct taccctagca
     1621 tctctattgc ccgtagtatg catactttcc atgtttgcga aaataatgtt tatctagtaa
     1681 atattgcggg atttcacata tattggggtt gatcagctcg ttttctttgg ccatcagaca
     1741 aatttcatct aagatcaaac tgttttctac tgctttcata ggtgaatccc cccatgtgaa
     1801 cggtccatgt ccatagacaa gtactccagg gacttcgttt ggatctaatt ttctttcctt
     1861 aaacgtctcg acaatcacat tccctgtatg aacttcgtaa gcttctctta cttcttcttt
     1921 cgttaattgg cgtgtacaag gaaccttacc ataaaaagca tcagcatgag tcgtgccata
     1981 agctggcaaa tcgcgtcctg cttgcgccca catgacggag tgcgtggaat gagtatgagt
     2041 aatagcagtt atatcttcaa aagtttgata caaaacaaca tgtgtgggga gatctgaaga
     2101 tggttttaag ctatcttctt ctattatatt tcccgacaaa tctgttacca ccatttgatc
     2161 tgcttgcatg cattcatatc tgacaccgct tggcttaatg acgatgactc ctagctcacg
     2221 gtccacttca ctcacattgc cccaagtcaa tttgactaat ccgtatcgcg gcaatgccag
     2281 atttgcttca aggacacgtt gcttcattgc tgcaattttt tcttcacaag acatcatagc
     2341 cagcctcctt caatttagaa cttaagtagt cttttgcctg ctggatttct cttcgaaagt
     2401 cttggctttt ttcactccac atttcaatca gaaatgttcc atcataatct agacgtttca
     2461 aatgtcttaa taatccaaga aaatcaacac aaccgctacc aaaaggaaca tcacgaaact
     2521 ggcctgaata ttcttttgtt acagggtaag tatcttttaa gtggatagca gtgatataat
     2581 cgatcccttt ctcaagttct cgagccggat tattttccgg ccatgcggac aaattgccta
     2641 ggtctggata tacttgtaga aaaggtgaat gaatctgttc tttgatttct aaaaattttg
     2701 aaatggagtt cataaatgga tcatccatga tttccacgga aagaatgatg ccatatttag
     2761 aagcttcctt tacgctttct tttattcctt cgataaagtc ttctctggaa ttcattgatt
     2821 tctcttcata ataaacatcg tatccagcta tttggattac tttgacgctt agattatgcg
     2881 ccaaatggat tgcttttttc attagttgtt tcgctgcttt tttcttttct ggatcagcag
     2941 aaccaaacgg aaatcgccga tgcgcactta aacaaatcga atggatacgt acaccggagc
     3001 tgaacatctc ttctctcagc tcagctatct tttcttcaga ccaatctaat cgtgctaacc
     3061 gctcatccgt ctcatcaatc gacatctcga taaaatcgaa gtccatttct tttacaaggg
     3121 aaaaacgttc tttccatgaa atatctttgg gtaacgcttt ttcataaatc ccaatttgag
     3181 ccatttcctt acccccagat acgaatgatc tcatctttga agttttgtgc ggccttcatc
     3241 ggatcatttg ctgctgtaat accacgacca gtgataaagg tatacacatc gatcccttca
     3301 aataagtgta atgtgtgtgg atttaatcca ccagttacag aaacattaaa gcctagttca
     3361 atcagttttt tgatcttcga taaatctttt tcaccccaag tttcaccaga taacagcgca
     3421 tcacggcttt gatggtagat tacctgccgg ataccgatgt tatgccaatc catggcttgt
     3481 tcaaaagtcc aattgccgta gagttctact tgcaattcac ctatttcttt ttgtgctgcc
     3541 tccatagttg gaatcgttgc acaacaaatg actgtcatcc agtctgctcc tgcttttgca
     3601 acattactcg ccactgttcc tccagcgtct gcacatttcg tatcagcgac tagtttttta
     3661 tctgggaaca tactgcgaat acagcgaatc gctttttgtc cttcctgtaa gcaaagaatt
     3721 gtgcccactt caataatatc tactacatca ccaactttca taacatctcc taatgcatgt
     3781 tctaagtcat tgtgatctaa cgcaatttgc aaattcggcc tgctcatctt agttccttcc
     3841 tttacttgtt tttttggtac cactttgttt cagcaaattt ttcactgatt tctttgactg
     3901 acatcacatt tttgataccg ataactgtaa ctcctttttt ctctgcctga gtaaacatat
     3961 tcaaaaaatt gactggcgta aaaactacat cgtattggcc agctgaactt tttccctctg
     4021 aaatggcaca atgatggatt ttggtaattg gtacgtttag ttctttcatt gctttttcca
     4081 cacttctcat catcatcaag cttgttcctg atccatttgc acacgatact aaaattctca
     4141 tcttaatccc tccattatga gtgttgtcta atcagatttt cttttatact ctctgctttt
     4201 ctgcatatgt gtcatagtct tctacaatca aaaaataacc atcaggattt ttccgatatt
     4261 gtaactgcgg aatagccaat aaaccaatga caactacggc aattccagca taacctagga
     4321 ctttcatgat tactgtaaac aatggccaag ctgttgccca gtcgaacatc ccgatataac
     4381 caccgtatgt tgacatccca atccatgtag cgaataatgc tgaaccgcct acttgtatga
     4441 ttcctgaaag aaacgggaac aggcaagcgg ctttgaatcc acctcggtta ttggcataaa
     4501 ctgctataac ggcattatca aagaacaacg gaatgaaacc ggctatgacg atcgttggtg
     4561 atttcaataa aatcagtaaa ccaatcatca aaaactgtcc caaagcacca aacaagaacc
     4621 caatcgttac cgcatttggc gaaccaaagc caaaagtagc agctacgtca attcctggaa
     4681 cagctcctgg taaaatcgtg tttgagattc cttggaaaga ttgagttagt tcatcgacga
     4741 atgtccgaac acctaattgc aagatcgcca gatataccgc aaaatttaaa gaagtcgtca
     4801 taatgtagaa taagaaactc tgcccttctt gcatgaattg cgcttgaatc aaataatctt
     4861 tgcctagtac aatcagaatg atcccaaaga aaaatagcat gagtaacgaa gtagcaacca
     4921 tattctcatt gaaaatcgac aagaatcctg gtaatttgat atcttcaatt tttttgtctt
     4981 gcttgattga tctatttttc ttttcatccc gctttttcat ccactcagct aattttgcaa
     5041 atataaagat tccgaacatt tgctgatgtg ccactgcaaa tccggcacct tctgtcaatt
     5101 cctgcgtgat tcctactgtt aagttagaag ctactgtcca ataacaacct aaaatcagtc
     5161 ccataaaaat caatgcttgt atcctaccta gatcaggaaa gcaaaacagt aaaatccaaa
     5221 aagcggtagc tgcttgttga acctgaacgt ttccggtagt gaaaacggaa cgcagtttcg
     5281 tatatttctg aaaacggact aataagatat ttaaaacaaa tgcaatcagt aataaaatca
     5341 tcacatctcc aaaggtacgg ccaaatgtct ccattaatcc agcatccaca gcattttgtc
     5401 caaaataagg atctgtaacc atggcatcca aattgaaccg ttcctttagt ccaaccaaga
     5461 ttggccgaaa attattgacc aaaccaccag agccaacagt caaaataaag taaccgaccg
     5521 ttgcctttaa gaatccagcg atgcattcat gaagcgggcg tttcagcaaa atatagccta
     5581 ataacacgat aaaaccaatc aggtatgctg gctgcgtcaa gatatttgtt gcaaaatacg
     5641 tccaaatgct taacaaaaat tcccccatct tttttctcct ctatcaatta attatattct
     5701 gccatcacaa cttggtaatc atcgatggag ttcgtagaga tgagacgctc aaccaatcca
     5761 tctgtcatta ataattcgga taatttttgg atattttcta gatgttcttc tggatctttt
     5821 gctgcgagtg taaaaaacaa actagccgtt ttctcctcat tctccccttc actttcaaaa
     5881 cggattggct gtttcaactt ggtaaatgaa atagctgttc caaaaacacc atcacttttt
     5941 tctgaagaat gcggcattgc tacttgaggt gcgatcacaa tataaggacc gtatttttct
     6001 acacaatgga tgatctcctc cacatacgtt tcatcaataa tttccttatc gatcaataca
     6061 agacagcttt cggcgatagc ttcacgccaa tccgtgattt ctttatctgg gtaatgaatc
     6121 aattgatggt caaaaaagta tttcagcaag aaactcccct tctttcttat aaaaacgacg
     6181 gaaacggtgt atcattttca atcgagaaga catcttcaaa tcctcgataa aaattaaact
     6241 caagatcatc tttgtttgtc ggatagatga atttcccgcc tacttgccag atataaggtt
     6301 taaatccata cttcaggcga tcctttttga atttccaaat ttcagtgatc tcttttggat
     6361 cagccataaa attagaccaa atatcgtagt ggacaggaat cactactttt gcattcaatg
     6421 actccgccat gcgcagcata tcaacagaag taactttgtc tgttatccct cgtgggtttt
     6481 caccataggc ccctaaacag acatcgattt tgtgttcatt accatgtttg gcaaataaat
     6541 tggagtaatg tgaatctcct gcatgataaa gattccctcc tgatgtttcg aataaatagt
     6601 ttactgcaat ttgatccatc tcctgaggca tttttccttt taatacctct tctggatctt
     6661 cacaagtgac caacgctgtc cgatcaaacg cttctaaagc tactacattg atgtctttga
     6721 ttttgactgc atcacctggc tttactgtaa tcgttttttc ttcaggaatt ccccattttt
     6781 gccacgtgcg aaccacttct tttggcccaa tgaatgttgc ttcaggacaa ttttgatgaa
     6841 ctgctgcggc tgtatggata tctagatgat cggaatggat atgtgtaacg attaaagcgt
     6901 ctacattttt tatcgcaaaa ggatcgatta cgaaaggctg agtacgtaaa ttaggctgca
     6961 tattttgaac gccactcata cgcatcatct gatggccttt tttcatcatg ccattcccat
     7021 gactacgttt tcccgtccca caccatagat cacataaaat attcgttcct tcatgacttt
     7081 tcagccaaat tcccgtacag cccagccacc acatagcaaa agttccagga tccactactt
     7141 ctgtttcgat ttcttcattc aagtatgtgc cccactcagg aaatgtttct actaaccact
     7201 tttcttttgt tacttcattg acagttttac tcatttgctt gctcccccca tatcgttgtt
     7261 ccaacttaca agtaaatatt aatgtgtatc agcatccatg aaaacccttt tatatgaccg
     7321 tttgtttttt atatgatttt ctttcagtaa tcaatgattg tttcagtata ataaagacag
     7381 atatgaatgt ttaaatgaac aactagtcaa ataaatccat ggatcaagat gtccctcagg
     7441 aggcaaaagt catgaaaaac tcacttgtca atattgaaaa acgtcaaaaa gaaattttgg
     7501 aactgcttca gcagactgaa caactatcaa ctttcgaatt agctgaatcc cttgatgtat
     7561 ctattagtac gatacgaaga gatttaaatt tattagaaga aaaaaacgag atcatacgca
     7621 attacggtta ttgttcttat aattacaaaa accagactga ttttgatcaa tctggtcctg
     7681 aaaggattaa acaagcgatt gccagagaag ctagtaaata cattaacgat tatgatacgc
     7741 tgtttatcaa ttctagctcg actgcgttga aaacactgga ttttcttcaa tctaaccatt
     7801 tgacagtcat tacaaacaac gtgaaaatca attactctcc gcacaaagat aattgtagtt
     7861 atattttaac tggtggagag atgcgctttc caaaagaagc actagtgggc gacatcgcat
     7921 taaatacgat ttcttcagtc aatgcagaca tttgtatcat tggctgtagc ggagtcgatg
     7981 tagtacatgg ggtcacaaca aagatattaa atgaatcaac gatcaacgaa atgatggtca
     8041 acaagacaat caaatgtaag attttagtcg ctgatcatcg aaaaatcgga ctgacatcaa
     8101 agttcaagat tgctgatatt tcagtctttg attatttgat cactgataaa ttttgttctg
     8161 aaaaagtatt agaggagatc agaaatacgg ggataaaaac cattcaagta gattcatttt
     8221 aagaaccagg acgtaaatat gtaaatagga ttatcaaaaa aatgaataac aaatttatcg
     8281 ataaatgaaa aacacgctac gctcaaattg ataaaggaat cccaagatgt atccatccaa
     8341 tcgataccat cataatctat tgcttctttt ataaccgtta tatgttgcct aaataggaat
     8401 caaacaatat cgaaaaaagg aggtatgaca aaagtcacac ctcctttttt cgaataaacg
     8461 gtattcaaat cagaacactg atttcacaac cactttattt caggtcgttt tcaatcacct
     8521 ttaccgcgta atcatttccg ttgaaacgcg ctattttttt tgcgtccata tatctttcta
     8581 aataatcatc ttctcctaat tgcttatggc aagaagcaat ttcataaagc aagtattcca
     8641 atgcataagt cgatttatgt ttcttattat actcaatacc cttctcacat aattggattg
     8701 ctttatcata atcctcgatt ttacggtaat aggtggcgat atcataatat acaatgcaga
     8761 ccatcagatt atcaaaatca gtctcactca atattttaag tgtacgctcc acataaactt
     8821 tcgcaaaatc taattctcct tttgacaagt agatcattgc cacgtttgca gctgcttgta
     8881 agtgatggat atctgtttcg gtcgtttgtt ccaacacttg attaaaataa aataatgctg
     8941 catctggttt tttcgcataa agatgatcaa gcagtccttg ataaaataaa atttgattta
     9001 aaagatcaga attacttact ttttcctgat cgatcgtttg taaaatttta taagattctt
     9061 ggtattttga tacagaattc aatgattgaa tctcatttat ttttttcctg attttgtctt
     9121 cttctgtttc tactaatata tcggagatct cgacattcag ctttttgcaa agcgcactta
     9181 agatattgat gcctggcgac atattcttgt tttcgatatt gctgacagtt gcttgttcac
     9241 aaatgccttc tgctaattgt acttgtgtta accccttttt ctttcggtat tcttttagta
     9301 atgctccatc tactttaatc aaaacaattt ccttcccttt aaaaaattat ttctccttta
     9361 tatcatacac aaaaaaaagt tctaaacaac caaaaatgtt tagaacagaa taaaaatttt
     9421 aattttaaaa taatattcaa attaaacaac tggcgtatct gctccttgat ttctttttgt
     9481 gttatctgaa taattatcgt ttacagttat aacacatagt gaaaattgtc atggcgagaa
     9541 agtctaagaa tatttttaaa cataactatt tctttcttac gtgtgtataa tgacgacagc
     9601 acacctatca attaatataa ttattttatt tttttatgtt ctcatgttta tttttaatga
     9661 cacaacttct cgtatttatc tggcacaaca tataaatcga tcaaaaaatt gttgcgtgtt
     9721 tttttgaaaa ttggagtttc aacttgatta caaaatttaa atttagaagt tgtgaaaaca
     9781 gcgagagaca gtttaatatt caaaatatac ataggctact cgaacgctgt gttttttagt
     9841 atactagtaa gaaacgaagg gatagactca ttccaataag gaggatttca tgaagacaat
     9901 tctttttgct cctgcagtat tcaatttagc tgagacaaca cgaatgattg aggttgccaa
     9961 agctatgaaa gaccgttatt actgtgtatt ctttggcttt tctaaaactt ttgctccttt
    10021 gatcacagaa agtggctttg agtatcattt actagcgccg atccttacga aaaaacaaga
    10081 agaacaaatc ataaaatttg accagttgcg tacacttaaa aaccctttta ccaaagaaat
    10141 ggttgcctct cgtatcacta gtgaacagag tctgattgct aagtttgagc ctcgactgat
    10201 tgtgacaggt tcgaatgtga caattttttt atcggcccgc aataaaaaga ttcctttagt
    10261 atatgttaaa ccctatgctt tgagtgaacc tttttttcaa tcagagcatg cgctgatgcc
    10321 ccacgagtta cgtttcttcg gccctttaag caatcccctt tggcactgga caaaaaagcg
    10381 tatagtaaat acccgatgga tccccaatgc cttcaaacac gctgcacaaa aagaaatgct
    10441 tcctttacca aaaacaagtt tacaaatgat ggatgctgat ctaaatctca tcacaacgcc
    10501 taaactattt ttggaagaag aacagctgcc ggaaaattat cgaatcgttg gtccaatttt
    10561 tgctaagctc agtacttcct tgcctgaaga agtgctaact tttatacagc gaaagcaaca
    10621 agaaagaaaa cgtattatct atttcgcaat gggtagttca ggcaatccgc gtatgttacg
    10681 caaaattttg ttcttcttac aaaaacaacc ggatctagcg gttattgcac ctattgacta
    10741 tctgcttgat gacattcaat ctgactcaga agatctttta ataacagaat atctgtctag
    10801 tcatcttttg catgaattca ttgatttttc ttttatccac ggcggggaag ggaccgtcca
    10861 aactgcctgt gaatccggca aaccgtttat cggtgtgggg atgcaatttg agcaaagctg
    10921 taatattgac tattgtgtaa aatacggaaa cgcaatcgcc ctcacaaaac cagtgactga
    10981 aagaaaactg cagattgctc tgcgcgaagt ttcttcaccc aagattcgtc agcaggcacg
    11041 cacgctgcaa gccgtttttc caataaatgg tccacaacaa gcaattcaag aaatcgaaac
    11101 cttcctgagc aaccacccaa tatagtttca agtagaaaaa gcttttttaa tagagactca
    11161 tcagtaattt cgctattcga gacccagaca gtgaaaatac aaaaaaagta aatagtggat
    11221 tgaaaagtta gagttactta aattacggtg tctaaaaaac acaaaatcat ccttaaaata
    11281 aaagatctga cgctatccaa atgagcatag gtagcgtctg ccatttattc ttagtcaaat
    11341 tctttgacac ctttctctgg ttggatcatc tcaacgtttc ttcaaaagaa agaccataat
    11401 aattaggcaa atacattttc ttaaaatgtg tcatatagat ctagaagcat cgctttgtag
    11461 agatttgtgc cgctagtccc ctcaacaatt actaaatcaa atgtaggatt taccacttta
    11521 tctttgataa tcaacctccc tcttctgttg agacaatgat ctcgcaatcc gatgcatact
    11581 cctatataaa ctgccagcaa tccccacata ttgagtagat catgtcagaa tgttctatgt
    11641 cgtcagcaac gatacactaa aagtcacgtt caccatgact gattgctatt cccagcacaa
    11701 ttatttctat acacgtttca tgatttgaat aaacactcac atcatacata ttaccattca
    11761 tacaccatac tgcagcccct actatatggt tgtaagctcc caaatctata tttgacttga
    11821 tcactttggt agtagatcta ctaattctaa atccattgct gataaaattt ccattttttc
    11881 ctccttcttt ctgccaaaac agttaaaaca ataataatct ttatgtaaaa aagggctgtg
    11941 acaaaagcct tgtcacagtc ccatattccg aataaacggt ggtcaaaagc ttgcatctgc
    12001 ggtaataagt tcaaccaaac gaaaaataag ccaacatttc acaaaaattt aagaagcaat
    12061 tttcgtaaat ttcttcttat ttcttgaagc taaccacttc tgttacaacc acttttagaa
    12121 catttaaagc ttcgatgtga caaaccatct atgctgctcg atcataaaat tgatagcaaa
    12181 aattccacaa agtacatatg tcccccatga aaacaaaaca ttcatatgcg gtacaatgat
    12241 ctttggaaga atcacgatca aaaatgatgc cagtgcccaa atccatcgat tgatttgaat
    12301 atgatatgta gctagcatat tcaatataag gtgactagcc gttaataaaa agataaaaac
    12361 aaaaaataaa atcagccaat acattgtttc ccaccttcta aaaaccaaac ttagacagtc
    12421 tggacttcgt tttctccacg actttgttca tctgacagca tctttttatc ataagctttt
    12481 acaaatggat aatagataat aaatgctatc aatgtgttga tcatgatcaa gataacaaca
    12541 cgccagtcat ttcctgctga aagataaccg ccgattggag ctggtaatgt ccatgttggc
    12601 aaaacagtaa atctattgac catttctaat ttgactgcaa aataactgat aatagtcaaa
    12661 actaaaggaa ctaagttgaa cgggatgaac atgtaaggat tcaacatcat aggagctcca
    12721 aaaattatgg gctcattgat attgaagata ccaggaataa tagaaaaacg accaacctct
    12781 ttcaagaatt ttgatttaca gaagaatata aacaaaacag ataccacgat cgttgctcct
    12841 gcaccaccaa ttgttaccgt ccattgataa aactgttcag gagcgatata gggtaattgg
    12901 gtggcagctg taccatctgc caatgccttt gcattctcat ccaacatgat cagccacatt
    12961 ggacgaacaa cagcccctac aatactcatg ccatggatac caaatgacca caacaaatgg
    13021 atcaaaaaca ttggtagtaa aacaccaagc aaattattcc ctaaaatatt ggttaaaggc
    13081 tcgaataacg ataataaggc agcgtttaca tcaaagcccg cgacgcttcg aatcagccaa
    13141 gtaattgtta aaatgactgc acctggaatc aatgcctcaa aactacgggc aacagcaggt
    13201 ggcacttgtt ctggcatttt gatagtaata tttcgatttt taaagaaacg atatacttcc
    13261 actgcaaaaa tcatagataa gatccccgca aacatcccag atgctcccaa agaactcata
    13321 ggtaagaccc agccaagagg tgcctcttca ggagttaaaa cgtttacagg aacttgtaac
    13381 ataaagaacg ttcctaaaga taatatacca cctgtcacac tatctaatcc atatgattta
    13441 gctagatccg aacccataac aaaagttgca taaatagcca tcaatcccat cgtcatccta
    13501 aagggtaaaa caatcgttgc cgaataaggg gcaataaatt cattccatcc aggaaacggt
    13561 aaattgataa agaccataaa aaatgtccca atcaaaatca atgacaatgt tgaaacaacc
    13621 ccattacgaa ttgctaataa atgacgctgt gtaccaattt ttgccattgg tgggacaagt
    13681 ttctcttcga cccatttcat cagcttttcc actaaaacca ctccttttca ataaaatatg
    13741 aaccattcat tgcatgacaa cgcaaagaat gttcataact aattatataa ttaagaaatt
    13801 ttatttcaat atattctctt aaataatcaa atttattttt aagaatcctg aaaataagtt
    13861 ttctaaatca taggagcaac aaaaaaattc gataattaac aaaaatcaaa atgattaaat
    13921 ctagtgattg aaacatatca tttcaaaaaa attttgtaaa ttcacccata aatatcaccc
    13981 tatttaactt ttttcatcgt acactaaaat tcaaaacaac tatctttaat ctttacttct
    14041 tggttttgtt ttaataaatt tccttcaaaa atgcctggag aaactacaat gatcaccgta
    14101 tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt cccttctttt
    14161 acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc aactgtatct
    14221 aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat ggcatgtcgg
    14281 gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc atcatgattc
    14341 gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt tactgctgtt
    14401 aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt aaagaaatgc
    14461 actttttatc acctctactt taatgctggc caatattttt tgtttacttt gatcatttca
    14521 tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt aaatgcttgt
    14581 aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc tactgcaact
    14641 tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt aattggctcc
    14701 acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg tagattcgga
    14761 atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt caacaaggaa
    14821 atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa tacttcttcc
    14881 acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg tccatccatg
    14941 accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc aggatataag
    15001 taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat gactgacatc
    15061 atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac ttgcatttct
    15121 tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc tttatcataa
    15181 atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca attcttacga
    15241 tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc acaggcatta
    15301 atcattttta cattcggata tttacgacga acagcttcag aaacgatcga ctctggattt
    15361 gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac aatttccaat
    15421 aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt ttcttgtcct
    15481 actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa tcctccaaca
    15541 cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc atccgttgca
    15601 cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat caagtacata
    15661 tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg caaccgtttt
    15721 tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc tccagctata
    15781 gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata atttattgaa
    15841 ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt tttcagttgg
    15901 tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca tggtgggatc
    15961 cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat tggcttttcc
    16021 tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg ctaaccctaa
    16081 ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac gtcctaatgt
    16141 ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg caaaaaagaa
    16201 aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga tgagataatc
    16261 aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac agacaatccc
    16321 tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa acatgaaact
    16381 aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc ttcccatgat
    16441 tcctttgacc atctctttat tttctttata agctgcttta tagatagcta gacatatagc
    16501 tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag cctgaggatc
    16561 tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag atgtatagct
    16621 tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg ggatcagcaa
    16681 acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga gcagttttgc
    16741 aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa cagctgcgat
    16801 tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat aagaaaaaac
    16861 tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta aaccggaaat
    16921 aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc cttttttcaa
    16981 ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat ttttgacaaa
    17041 accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg catttccagc
    17101 tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga tcaatcccgc
    17161 taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca catttgattt
    17221 aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac tcaatcaaag
    17281 gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact tggtgggtac
    17341 gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct gcgtgacaca
    17401 tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa tattcttcca
    17461 cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg aaacaaggct
    17521 caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga accggcaaat
    17581 catatttttt tgctaatgta acaactacct cctgattttc atccaaagta tgagtatgat
    17641 gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga atctgagcat
    17701 tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa taagataagg
    17761 atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt ttgccacacg
    17821 tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt ttcacagcat
    17881 gctcgaaacc cggcatattt gccatcaatg tagttgatgt caaaattcct cgctgataag
    17941 catccataat cccataattc acaccatggc tatagccaaa atcatccgaa ttaaaaatca
    18001 cttttcccat ttcattctcc ttcttttttc tactaaaata ggcgcaacca aataatcata
    18061 gtccatttac tatgtgtcat ttggttgcgc ctatagatag ttacgccctt attttaatag
    18121 attcttgcta gatgaattgc caaatagatg atttcatttt cttgaatggc aagttgaaat
    18181 tgctgttcga tgatatcttt aatctttagt gctgtacaat acgctttgct atgtttaaat
    18241 gtttcagtaa aaaaaccaat attttctact ggcgtttctt cctgataaat caagcgttta
    18301 accaggaatt tgatatgaac cattaagcga tgataagtca gtgattcttt atcataaacg
    18361 tttgaatagg atttttctag atgggacaaa atcgtggtcg tcatttctac tatttttaag
    18421 ctctttaaac tattaggctc tcctagctca gcattaatga tatgcatagt gatgaatcct
    18481 acttcatttg accctaactc ggtttgatat cgatgattga ttcgctcgac cacttctact
    18541 gctatatcat attcatttgg ataaaggaat ctcatttctg gcaacataat tgctgtgaca
    18601 tctctatctt ctctttttcg ttgaatagca aaataaatat gatctgtcaa tgtaatatag
    18661 atatttgaat ctaatggaga ggagatccta gctgttatca gttcaatcac ttcttccgca
    18721 aaatccataa attcgattgg aatctgcgag actatctcac tgaatcgttt gatcttttct
    18781 ttagaatcta atacaaataa tttgtcagca tcctcaacat caaatggctt actcacttta
    18841 gcagaaaagc caatcccttt ccccatcgca attttttcta ttccatcgtc atcgatcaat
    18901 acagcattat gattcagctt tttcatcaca tacaccgtta attcacctcc tctatatgat
    18961 aaaacaaaac aacttgcaga ctccttcata catatttttg tctccaaaca atttttaaag
    19021 acaaaaaacg acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa tagtagcacc
    19081 ctacataatt tacaaaaata gtttaacaca taataaaagc gttatcaata tcttttttac
    19141 tcgttttatg ataatacttg tatcgaattg atttggaggt aattacataa aaacaaaaaa
    19201 aatatagcaa ctctctataa gaaagttgct atattgataa ttataccggc ggccggggtc
    19261 gaaccggcac gtcctcaacg gacactggat tttgagtcca gcgcgtctgc caattccgcc
    19321 acgccggcaa atttaaaaat aataactggg gtagctggat tcgaaccaac gcatgaggga
    19381 gtcaaagtcc cttgccttac cgcttggcta taccccaaga ataaagggcg aatgatggga
    19441 atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc cacattcgcc
    19501 atcataaaag atgttattta atttctcaat aaaaaactaa gatgaagaca tcttagtcaa
    19561 taccggcggc cggggtcgaa ccggcacgcc ctcaacgggc actggatttt gagtccagcg
    19621 cgtctgccaa ttccgccacg ccggcaagtt gatttattag tactaaggcg gtaaccggat
    19681 ttgaaccggt gatgaaggtt ttgcagacct ctgccttacc acttggctat accgccatta
    19741 tactattatc aatctataaa ataaagaata aattatagaa actggggtag ctggattcga
    19801 accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa
    19861 aaagggcgaa tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac
    19921 cacttcgcca cattcgccat ggcaggggca gcaggaattg aacccacact aacggttttg
    19981 gagaccgctg ttctaccttt aaactatgcc cctataaaat ggaggagagt ggattcgaac
    20041 cactgaaccc taaggaacgg atttacagtc cgtcgcgttt agccacttcg ctactcctcc
    20101 atggtggcgc gggacagaat cgaactgccg acacacggag cttcaatccg ttgctctacc
    20161 aactgagcta ccgcgccata ttttaaaatt attaattgaa taacaagaac gacggttccg
    20221 acgggaatcg aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg
    20281 gaaccagttc attatggagg ttaacgggat cgaaccgctg accctctgct tgtaaggcag
    20341 atgctctccc agctgagcta aacctccaac attcaattaa aatgacccgt acgggattcg
    20401 aacccgtgtt accgccgtga aagggcggtg tcttaaccgc ttgaccaacg ggccaggtaa
    20461 atttgctacg gagagtaagg gattcgaacc cttgagacag tttggcacca tctacatgat
    20521 ttccaatcat gctccttcgg cctctcggac aactctccag agtgaaagaa gctcaatact
    20581 ctttctcaaa atgagaactc cggcagtagg actcgaacct acgacatcat gattaacagt
    20641 catgcgctac taccaactga gctatgccgg aataacatca gcgtggcgac gtcctactct
    20701 cacaaggggc aacccctcac tacaatcggc gctaagaagc ttaacttctg tgttcggcat
    20761 ggttacaggt gtatccttct cgctatcgcc accacactgt ggtgttatct tttattgagt
    20821 aaattttgtt cactcaaaac tggatttgaa gtcacataag tttttttccg agt
//
LOCUS       DARBDN010000045        20505 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000045 DARBDN010000000
VERSION     DARBDN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.045"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(105..629)
                     /locus_tag="SCH06_001601"
     CDS             complement(105..629)
                     /locus_tag="SCH06_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078166.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="SCH06_001602"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="SCH06_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEG1078167.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="SCH06_001603"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="SCH06_001603"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEG1078168.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="SCH06_001604"
     CDS             complement(2351..3031)
                     /locus_tag="SCH06_001604"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEG1078169.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="SCH06_001605"
     CDS             3157..4026
                     /locus_tag="SCH06_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078170.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="SCH06_001606"
     CDS             4052..4567
                     /locus_tag="SCH06_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078171.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="SCH06_001607"
     CDS             complement(4614..5207)
                     /locus_tag="SCH06_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078172.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="SCH06_001608"
     CDS             complement(5232..5411)
                     /locus_tag="SCH06_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078173.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="SCH06_001609"
     CDS             complement(5488..5997)
                     /locus_tag="SCH06_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078174.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="SCH06_001610"
     CDS             complement(6093..6473)
                     /locus_tag="SCH06_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1078175.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="SCH06_001611"
     CDS             6803..7552
                     /locus_tag="SCH06_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEG1078176.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="SCH06_001612"
     CDS             complement(7736..9013)
                     /locus_tag="SCH06_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078177.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="SCH06_001613"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="SCH06_001613"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEG1078178.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="SCH06_001614"
     CDS             complement(9935..10879)
                     /locus_tag="SCH06_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEG1078179.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="SCH06_001615"
     CDS             complement(10881..11567)
                     /locus_tag="SCH06_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEG1078180.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12041..12361
                     /locus_tag="SCH06_001616"
     CDS             12041..12361
                     /locus_tag="SCH06_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEG1078181.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12515..13420
                     /locus_tag="SCH06_001617"
     CDS             12515..13420
                     /locus_tag="SCH06_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1078182.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13417..14190
                     /locus_tag="SCH06_001618"
     CDS             13417..14190
                     /locus_tag="SCH06_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEG1078183.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14371..15795)
                     /locus_tag="SCH06_001619"
     CDS             complement(14371..15795)
                     /locus_tag="SCH06_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1078184.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16006..16452
                     /gene="nrdI"
                     /locus_tag="SCH06_001620"
     CDS             16006..16452
                     /gene="nrdI"
                     /locus_tag="SCH06_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEG1078185.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16517..18499)
                     /locus_tag="SCH06_001621"
     CDS             complement(16517..18499)
                     /locus_tag="SCH06_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1078186.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="SCH06_001622"
     CDS             complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="SCH06_001622"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEG1078187.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19412..20473)
                     /locus_tag="SCH06_001623"
     CDS             complement(19412..20473)
                     /locus_tag="SCH06_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEG1078188.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
BASE COUNT         5921 a         4347 c         3633 g         6604 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaaaaatata gttgttttct
    11641 cacgaaatag acactatttt taaatatttt tcgttatttt tttatcacaa aaattatctt
    11701 acttattgta aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc
    11761 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
    11821 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
    11881 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
    11941 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
    12001 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
    12061 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
    12121 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
    12181 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
    12241 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
    12301 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
    12361 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
    12421 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
    12481 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
    12541 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
    12601 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
    12661 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
    12721 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
    12781 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
    12841 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
    12901 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
    12961 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
    13021 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
    13081 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
    13141 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
    13201 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
    13261 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
    13321 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
    13381 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
    13441 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
    13501 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
    13561 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
    13621 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
    13681 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
    13741 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
    13801 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
    13861 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
    13921 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
    13981 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
    14041 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
    14101 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
    14161 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
    14221 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
    14281 tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc
    14341 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
    14401 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
    14461 atgttgtaca ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
    14521 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
    14581 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
    14641 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
    14701 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
    14761 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
    14821 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
    14881 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
    14941 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
    15001 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
    15061 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
    15121 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
    15181 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
    15241 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
    15301 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
    15361 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
    15421 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
    15481 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
    15541 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
    15601 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
    15661 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
    15721 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
    15781 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
    15841 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
    15901 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
    15961 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
    16021 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
    16081 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
    16141 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
    16201 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
    16261 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
    16321 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
    16381 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
    16441 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
    16501 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
    16561 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
    16621 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
    16681 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
    16741 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
    16801 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
    16861 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
    16921 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
    16981 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
    17041 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
    17101 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
    17161 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
    17221 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
    17281 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
    17341 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
    17401 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
    17461 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
    17521 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
    17581 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
    17641 gaccgatggc aatcaatgaa agagttggtg taacgatgat atctaccgca tcaggtacta
    17701 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
    17761 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
    17821 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
    17881 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
    17941 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
    18001 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
    18061 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
    18121 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
    18181 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
    18241 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
    18301 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
    18361 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
    18421 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
    18481 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
    18541 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
    18601 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
    18661 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
    18721 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
    18781 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
    18841 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
    18901 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
    18961 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
    19021 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
    19081 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
    19141 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
    19201 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
    19261 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
    19321 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
    19381 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
    19441 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
    19501 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
    19561 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
    19621 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
    19681 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
    19741 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
    19801 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
    19861 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
    19921 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
    19981 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
    20041 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
    20101 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
    20161 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
    20221 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
    20281 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
    20341 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
    20401 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
    20461 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatt
//
LOCUS       DARBDN010000046        20485 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000046 DARBDN010000000
VERSION     DARBDN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.046"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            4..552
                     /gene="hslV"
                     /locus_tag="SCH06_001624"
     CDS             4..552
                     /gene="hslV"
                     /locus_tag="SCH06_001624"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HEG1078189.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            566..1966
                     /gene="hslU"
                     /locus_tag="SCH06_001625"
     CDS             566..1966
                     /gene="hslU"
                     /locus_tag="SCH06_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HEG1078190.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            1984..2775
                     /gene="codY"
                     /locus_tag="SCH06_001626"
     CDS             1984..2775
                     /gene="codY"
                     /locus_tag="SCH06_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEG1078191.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            2857..3732
                     /locus_tag="SCH06_001627"
     CDS             2857..3732
                     /locus_tag="SCH06_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEG1078192.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(3864..4502)
                     /gene="plsY"
                     /locus_tag="SCH06_001628"
     CDS             complement(3864..4502)
                     /gene="plsY"
                     /locus_tag="SCH06_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEG1078193.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            4629..5063
                     /locus_tag="SCH06_001629"
     CDS             4629..5063
                     /locus_tag="SCH06_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEG1078194.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5229..7274
                     /gene="parE"
                     /locus_tag="SCH06_001630"
     CDS             5229..7274
                     /gene="parE"
                     /locus_tag="SCH06_001630"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEG1078195.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            7286..9736
                     /gene="parC"
                     /locus_tag="SCH06_001631"
     CDS             7286..9736
                     /gene="parC"
                     /locus_tag="SCH06_001631"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEG1078196.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            10013..12244
                     /gene="pflB"
                     /locus_tag="SCH06_001632"
     CDS             10013..12244
                     /gene="pflB"
                     /locus_tag="SCH06_001632"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEG1078197.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            12488..13249
                     /gene="pflA"
                     /locus_tag="SCH06_001633"
     CDS             12488..13249
                     /gene="pflA"
                     /locus_tag="SCH06_001633"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEG1078198.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            13334..14260
                     /locus_tag="SCH06_001634"
     CDS             13334..14260
                     /locus_tag="SCH06_001634"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEG1078199.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            14442..15335
                     /locus_tag="SCH06_001635"
     CDS             14442..15335
                     /locus_tag="SCH06_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEG1078200.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            15469..15594
                     /locus_tag="SCH06_001636"
     CDS             15469..15594
                     /locus_tag="SCH06_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078201.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(15728..16360)
                     /locus_tag="SCH06_001637"
     CDS             complement(15728..16360)
                     /locus_tag="SCH06_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078202.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(16508..17050)
                     /locus_tag="SCH06_001638"
     CDS             complement(16508..17050)
                     /locus_tag="SCH06_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HEG1078203.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            17185..17574
                     /locus_tag="SCH06_001639"
     CDS             17185..17574
                     /locus_tag="SCH06_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078204.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            17578..18342
                     /locus_tag="SCH06_001640"
     CDS             17578..18342
                     /locus_tag="SCH06_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEG1078205.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            18471..19418
                     /locus_tag="SCH06_001641"
     CDS             18471..19418
                     /locus_tag="SCH06_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1078206.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            19548..20288
                     /locus_tag="SCH06_001642"
     CDS             19548..20288
                     /locus_tag="SCH06_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078207.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         7193 a         3481 c         4316 g         5495 t
ORIGIN      
        1 aacatggtcg aatcaccatt tcattcaacc actatctgtg ccgtcgaaaa agacgggaaa
       61 tttgctatgg ctggagatgg ccaagtaaca atgggtgaat ctgttgtcat gaaaggcact
      121 gcaaagaaag tacgacgtat ctacaatgga gaagttgttg taggtttcgc cggaagtgtt
      181 gcagatgcgt ttactttaga agaaaaattt gaaggcaaac taaacgaata taacgggaat
      241 ctacaacgcg cagctgtcga attagctcaa gaatggcgga cacagcaatc tatgcaaaaa
      301 cttgaagcga tgctgatcgt aatgaatgat aaagaaatgc ttcttgtttc aggtacagga
      361 gaagttatca caccagatga tggtatctta gctatcggat caggagggaa ttttgcgttg
      421 gctgcagccc gagcaatgaa aaactatgct caaaacgaca tgagtgcgaa agaaattgca
      481 gaaaatgcgt taaatattgc cgcagatatc tgtatcttta ctaatcataa tattatcgta
      541 gaagaactgt aagaggtgag tagatatgta tgaattaaaa caaacaccaa gacaaatcgt
      601 aagtgaatta gatgaatata tcgtaggaca gcacgcagca aaaaaatctg ttgccgttgc
      661 tttgcgtaac cgctatcgcc gtttgcagtt agatgaaaaa atgcaacaag atattacacc
      721 aaaaaatatg ctgatgatcg gacctacagg ggtcggtaaa acagaaatcg cacgacgttt
      781 ggcaaaaatc gtcaatgcac catttgtcaa agtcgaagca acaaaattta ctgaagtcgg
      841 ttatgtcgga agagatgtag aatcaatggt tcgggattta gtagaaaatg cgatccaaat
      901 cgtagaaaaa gagcagtaca gccgtgtata cacaagtgct aaaaaaaatg cagaaaaacg
      961 tttggtaaaa atcttggtac ctggtatcaa aaaagaacag aaacaatcca ctaatcaatt
     1021 tgaacaaatg atgaatcttt ttaatgctag tcagcaaaat accgctgaac cgcaagaaga
     1081 agtgacagaa gatattcgaa tcaatcgccg tacagtcttg gaacaactac aaaagggttt
     1141 actggatagt cgtgaagtaa ccattgaagt tgaagaccaa aagaaacctg caccaatgat
     1201 gaacaatgga ttggagcaaa tggggatcga cctaaatgaa actctaggtg ctttgacacc
     1261 gaagaaaaaa gtggaacgga cggtaacagt caaagaagct ttagagttat tgatcaagga
     1321 agaatcagca aaattagtca aggatgctga tatccatagt gaggcaatca aattagcgga
     1381 agaaagtgga attattttta tcgatgaaat cgataagatc acttctaaat cacagcaatc
     1441 tggagaagta tccagagaag gcgtccaaag agacatattg ccaattgtcg aaggttcaca
     1501 agtaaacaca aaatacggga tcatccaaac agatcacgtc ctattcattg cttcaggagc
     1561 tttccatttg tctaaaccaa gtgatctaat tccagaactt caaggacgct tcccgatacg
     1621 ggtagaatta gatgatttga cagctgaaga ttttgtgaag attctgaccg aaccaaataa
     1681 tgctttagta aaacaatacg tcgcgttgat cggtacagaa aatgtgtcag ttacgtttac
     1741 aaaagaagca attgaacgga tcgctcaaat cgctttcgat gtcaaccgtg acacagataa
     1801 tatcggcgca cgcagactgc ataccatttt ggaaaaacta ctagaagatc tattatttga
     1861 agcaccagat atgcaaatgg gagaaataac gatcacagaa gcatatgtgg atgacaaact
     1921 tggctcaatt gcggcaaatg aagatttaag tcgctatatt ttataaaaaa tcggaggacg
     1981 acaatgacag acttgctaac gaaaacccgc aagataaaca cacttttgca gcaaaagaat
     2041 acttttgaca tgcaagcaga tttgccttac gataaaatgg ctgtcacact aggtggtatt
     2101 cttgacagca acacctatat cataggaagt gacggagtat tactaggtta taatgaacgt
     2161 cacgatgtga acaatgaacg aatcaaaaca atgtttgttg agaaacaatt tcctgaatct
     2221 tatactgata cagtggcaca gttgatgaaa actgaagcta atatcccaat tactagtgat
     2281 attactgcat ttccggtaga gtcaagagag aaatatccat ttggtctgac gactgtcgtt
     2341 ccgatctttg gagctggcga acgtttgggt acgattatct tatctcgtat ggaacaatcg
     2401 tttgcagatg acgatctagt cttagcagaa tatggagcta cggttgtcgg tatgcagatc
     2461 ctttatcaga agtctcgaag catcgaagca gatgtacgga gtgcaacggc tgtccaaatg
     2521 gcaatcaaca cattatctta tagcgaattg aaggctgtac aagctatctt tgaagcattg
     2581 gatggagatg aaggtcgtct gactgcttct aatattgccg atagtatcgg catcactcgt
     2641 tctgtgatcg tcaatgcttt acgaaaattg gaatcagctg gaatcattga atctcgttcg
     2701 ttaggcatga agggaactta tttaaaagta ttgaattccc gttttaaaga cgagttagca
     2761 aaacacagtt attagaagta aggggactgg ggcagataga aatgtttgtt ccagccttcc
     2821 cattttaaaa agtaagtcga agttggagga atggcaatga ctgttattat tcaaaatgac
     2881 cagctgatcg ccgaaatcgc tgaacacggt gcggaattga tcagtctgaa atcaaaagaa
     2941 catggtttag agtatatctg gcaaggtgat ccagcgtatt ggggcagaca tgcaccggtt
     3001 ttattccctt ttgttggacg tttaaaagat gatcagtatg tttatcaagg gaaaacatat
     3061 caaatggggc aacacggatt tgctcgggat atggattttg aagtcattga acatggacaa
     3121 gaaatggcta gtttcatctt aaggagtacg ccggagacat tagaaaagta tccatttgat
     3181 tttgaattag tgatcagcta tgaattagga ggagacggca tcacggttca ttatcaagtg
     3241 gcaaataccg gtgaaaaaga aatgttcttt tctatcggtg gacatcctgc tttcaatgta
     3301 cctcttgaag aaggattgtc atttgaagat ttctatctgg cattttctcc attgaaatca
     3361 agattacgcc taccattgaa aggcccattc atcgatatgg atcaaaagac gttaggtcag
     3421 acaaatacga atctggcttt gaatcgtgaa ctttttgagc aagatgcctt ggtttttgaa
     3481 acaaggggtc taaatgcgta cgccattcga agtgaaaaat cttcccatag cgtaacttta
     3541 agctataaag atatgcctta tgtagggatc tggtctcctt atccaaaaga agcgcctttc
     3601 gtttgtatcg aaccgtggtg cggaatcgct gacacggtga acagtagtgg aaacttgatg
     3661 gaaaaagtag ggatcaatca actaggtgcc catgaaatct tcaagacaaa atattccatc
     3721 acagtgaagt aagaggttgt gaccgagaag ttagcaggga acaccgttta ccaaggtgtg
     3781 taaaaaagct atcctgtaag taataaggga gtgtgacatc gatttgtcac actcccgttt
     3841 tatctctttg gaatgaaaaa gtatcaggat tttttcttgc tgctattcaa accaaacggg
     3901 attcgacttt cagtatggtt tctgatacgc ttgatattgt ctttatgccg ataaaagata
     3961 aaggaagaaa ctaaaaaggc aatgatcgtc agtaaccaat tgggcttagc caaaatcaca
     4021 ggagctacat aaggaaggac gatcgtagat aaagtgatca atactgcact gatcatactg
     4081 ctcaaactca ccatacttgt acaaaataaa ctaacgataa agatgataca agaataaaca
     4141 aaaaatacag gattaaatcc taaaagcatt cctgcacttg tcgcaacagc ttttcctcct
     4201 ttgaacccag caaaaatcgg aaatgtatgg ccaagaatgg cgcatacccc aaaccaaaga
     4261 gggttaatcc cagaaaggtg gaagatcatc ggcaaacaag tagccaatgt accttttaaa
     4321 atatccataa gcaggacaac aatcccggct gttttgccta atacacgaaa tgtattggtc
     4381 gttccagtat taccgctccc gtgttgtcgg atatcttttt tgaaaaacaa tttgccaatc
     4441 cagacaccgg aaggaataga acctaaaaga tatgctaaaa taagtaataa gatcaatttc
     4501 attttttacc ctctttcaag ttgaaaacta tcctttattt tagcatgaat aggtaacagg
     4561 aacaattgaa aaaatgaaag atacaagtat aatagatgga ataaaaagaa aagcaagggg
     4621 tggcagaaat gtctgtaaaa aatccaacac aagaaacgat tttcaactat ttggaagaag
     4681 caaaaaatat tgccgtcgta ggcttgagca ataaaccaga acgaacaagt tacatggttg
     4741 cacaggtatt gcaagacaat ggatataaaa tcataccagt aaatccatta ttggctggtg
     4801 aagaaattct aggcgagaaa gtctatgcga atttgacaga aatcgatgat ccaatcgata
     4861 tcgtagatgt atttagacgg agtgaatttt tacctgaaat agcaggtgat tttttgaaaa
     4921 ctgatgctaa agtgttctgg gcacaattag ggattgaaaa caaagaagca gctgagatgc
     4981 taagaaaagc aggacgtaca gatatcgtaa tggatcgttg tattaagatt gaacttggta
     5041 agttgaaaga aaaccaaaaa taaaaatgac cacaaagaag agatgatcga tagaggggaa
     5101 tgtcgaaaaa gcggttagga gataattaaa attgatttct cgtctaccct cttttttttc
     5161 acgacctttt ctagtatgat aatcgtggtg cggttttgcc gcaaagtatt attgaaggag
     5221 cgtttgcctt ggcaaaaaaa gtaaacaacg aatacaatga ctcgtccatc caagtattgg
     5281 aaggattaga ggcagttaga aaaagaccag ggatgtacat tggatccact gacagccgag
     5341 gcttgcatca tttagtctat gaaatcgtcg ataatgcagt tgacgaagca ttatcaggtt
     5401 atggcagtga gattgatgtg accatccatg aagacaatag tataactgtt gcagatagcg
     5461 gacgtgggat gcctgtagga atgcatgctt ccggaatacc aacagttgaa gtgattttta
     5521 ctgtgctgca tgctggcgga aagtttggtc aaggagggta caaaacttct ggtggactgc
     5581 acggtgtagg agccagtgtg gtaaatgcct tatcgaaatg gctaattgta acgatcgtta
     5641 gagatggcgt agagtatcag cagaaattta aaaacggcgg taaacctgac ggtactttga
     5701 aaaagatagg aaaaacaaaa aaagcaaacg ggacgactgt ccatttttta ccagatgata
     5761 caatattcag tacaacgaaa ttttcatatg aaattttagc cgaacggtta agagaatctg
     5821 cctttcttct aaaaggcgtt aaaatctctc tttctgatct tcgtggagaa gaaccagtca
     5881 aggaaatttt tcattacgaa gaaggaatca aagaatttgt tgattatctg aatgaagaaa
     5941 aagatacatt gacaccagtt gtttattttt caggagaaaa agaaggtatc gaagtagagg
     6001 tcgcttatca atacaatgac ggttattcag aaaatgtttt atcttttgtc aataacgttc
     6061 ggacaaaaga tgggggaacc catgaagctg gtatgaaagc ggcgatgacg aaatcttata
     6121 atgaatatgc gagaaaagtt ggtttgctga aagaacggga caagaatctg gaaggtagtg
     6181 atttcagaga agggttagct gctgtacttt ctatccgtgt acctgaaaat cttctgcaat
     6241 ttgaagggca aacaaaagaa aaacttggta cgccagttgc tcgtaccgta gtagataacg
     6301 tcatcagtga acaaatgggc ttttatttgc aggaaaatag cgaaatgagc cagatgttgg
     6361 tccgtaaagc aatcaaagcc agagaagcga gagaagcagc acgtaaagcc agagaagaaa
     6421 gccgaaatgg gaagaagcgt aaaaaaggcg aatctcttct ttcaggaaaa ttgacacccg
     6481 cacaatcccg aaaccctaag aaaaatgaat tgtatttagt cgaaggggat tctgctggcg
     6541 gatctgctaa acaaggaaga gacagaaagt tccaagcaat tctaccttta cgaggaaaag
     6601 tcatcaatac cgaaaaagct aaaatgcaag atatcttgaa aaatgaagaa atcaatacga
     6661 tgatctatac gattggtgca ggagtcggtc ctgagttttc tatcgaagac tgtaattacg
     6721 acaaagtaat catcatgacc gatgcggata cagacggcgc ccatattcaa gtattactgc
     6781 ttactttctt ttatcgttat atgaaaccgc tgattgaagc tgggaaagta tatatcgcgt
     6841 taccgccttt atataaagta tccaaaggac aaggaaagaa gcaagtcatt gaatatgcgt
     6901 ggacagatga cgaattggca gcaatgatta aaaaagtcgg caaaggatat atgctgcagc
     6961 gatataaagg acttggagag atgaatgcgg aacaattgtg ggaaacaacg atggatccga
     7021 cttcccgtac gttgatccgc gtccgtatcg atgatgctgc gcaagctgaa cgtcgagtaa
     7081 ccacactgat gggtgacaaa gtagaacctc gaagaaaatg gatcgaaaat cacgtgcaat
     7141 ttacgctcga agaagatggc agtatcttag ataaaaaaga ggatactgaa atctctcctt
     7201 cagtttctaa tgatttatta gatgaagaac gagcagataa aaatgaaaac aatcagttat
     7261 ttgaagtaga ataggaggtc acctgatgga aaatcgacaa gaagtacaag aattaacttt
     7321 agaagaagtg atgggtgacc gcttcggacg ttattccaaa tatattatcc aagaacgtgc
     7381 actgcctgat atccgtgatg gattgaagcc agtgcaacgc cggatattat ttgccatgaa
     7441 caaagatggc aatacgtatg acaaaggatt ccgtaaatca gcaaaatctg tcggaaatat
     7501 catggggaat tatcatcctc atggtgacat cagtatttat gaagcgatgg tccgcatgag
     7561 ccaagactgg aagttgcggg aagtactgat cgaaatgcac gggaataacg ggagtatgga
     7621 cggtgatcca cctgctgcga tgcgttatac tgaagccaga ttatccaagt taagtggaga
     7681 gatgctagca gatatcgaga aagaaacagt cgatctcgtg tggaattttg atgatacaga
     7741 aaaagaacca acagtccttc cagctcgata cccaaacctt ctcgtcaatg gatcgacagg
     7801 tatatctgct ggatatgcaa cagaaatccc gactcataac ttagctgaag tgatcgatgg
     7861 cacaatctat atgatcgatc atccacaagc gagccttgaa aaattgatgg aatatattcc
     7921 tggacctgac tttccaacag gagggatctt gcaaggaaaa gatgaaatca aaaaagctta
     7981 tgaaacagga cgaggaaaag ttattcttcg ttcgaaaaca aagatagagg caatgaaggg
     8041 taataaacag caaatcgtga tcacagaaat cccatatgaa gtaaataaag cgaccttggt
     8101 gaaaaaaatg gatgagatcc gtttgaataa gaaaatcgat ggaatagctg aagtacgaga
     8161 tgaaagtgat agaacaggtc tgcaaattgt cgtcgaattg aaaaaagacg ccaatgctca
     8221 aggaattttg aattatttgt tcaaaaacac tgagctacag atcaattaca atttcaatat
     8281 ggtcgctatc gaccatatga ctccgcatca agttggactg aaagacattt taagaagtta
     8341 tatcgagcat cgaaagcaag tcataacaaa acgtagtcaa ttcgatttag ccaaagctca
     8401 aaaaagacag catatcgtag aaggattgat gaaagcttta tcgattctgg atgaagtaat
     8461 cgcaacgatt cgtgaaagta aagacaaaaa agacgccaaa aagaatttag tcgacgtctt
     8521 tcaatttaca gaagaacaag cagaagcaat tgtcacattg caattatacc gtttgacgaa
     8581 cacggatatc acagagcttc aaaaggaatc cgaaagcttg attgcgcaaa tcacagagtt
     8641 gaataaaatc ctttcaaatg acaaagagct tttctctgtt atgaaaaaag aattgcgaga
     8701 agtgaaaaaa aattattctt ccgctcgtct aacgacaatc gaagacgaaa tcgaagaaat
     8761 caaaattgat acgcaagtct tagtggcaca agaagacgta attgtcagtg tgacgcgaga
     8821 aggctatgtg aagcgaacaa gccttcgttc ttatagtgct tccaaaccag aagaaatcgg
     8881 gatgcgagaa ggcgactact tgctatactc aggtgaattg agtacattgg accatgttct
     8941 tctgatcaca aataaagcaa atgtgatcta ccgccctgtc catgaactac ccgatttgaa
     9001 atggaaagat gctggtgagc acatttctca aacaatctcc aatctgtctg tagacgaatc
     9061 gattttagct gttttcccat atcaaaaaat tcaagcagag aaaacatttg tattcatcag
     9121 caagaatgga ttgatcaagc aaacacgaat gacagagttc gaaccatggc gcacctataa
     9181 gagccgtccg ctcagctgta tgaagctaaa ggcggaagaa gatgaactga ttgctgtgta
     9241 tctgaaagaa gatcagccag gcttagatgt tttcttagta acgcatcaag gaatgggttt
     9301 gcgctatcct ttaacagatg ttcccgttgt tggagcaaag gcagctggag tgaagtctat
     9361 gaatttgaaa gatggagata ggattatcaa cgggctgctt gtgttagcag aaggtgatac
     9421 gccgatcgta atcgttactc agcgaggagc tgttaaacgc atgcttgctc aagaaatcag
     9481 ccaaacttca cgtgcgaagc ggggagtgac ggtcatgcgt gagctgaaaa aaaatccgca
     9541 ccgtattatc tatatgtcgg aaggaagatc aaaagaaata accttgatga atcaaaaagg
     9601 gcagcagtta acgattgacc caactgattt ccctataggt gatcgaacat cgaatggatc
     9661 atttgcgatg gatgagaaaa aaggtggaga agtcatcgaa gttatcgatg ctcctgagat
     9721 tttcatcgag tcgtaactgt tgtagtattt taatgaagag acgccatctg tattaataca
     9781 ggtggcgtct ctttttcatt catttttaat aaatccttat acgtttgcaa aaaaagatga
     9841 aagtgttcac aatgcttaaa tgttggtatg tcaacgttga tttaaatata tgtaaataaa
     9901 acataaaaat tgttaaataa aaaacaagaa aacccttgca aagatagggt gctgtgttat
     9961 actaatcacg taaaaactgt tacataaaac agaaatttag gaggtccata caatggagca
    10021 atggaatgga tttaaaggta ccaaatggaa agaaggcgta gacactagag actttattca
    10081 aaataactac actgaatatc gcggtgatga cagctttttg gaaggcccaa cagaagcaac
    10141 agaaaaatta tgggatgaat tgcaaaagtt aaatgatatc caattcgagc gtaacggtgt
    10201 ctatgatatg gacacagaaa tcgtatcaac tattacttca cacgatgcag gctatttgga
    10261 taaagatttg gaaaaaatcg tcggtctaca gacagacaaa cctttgaaac aagcattcat
    10321 gccgttcggc ggaatcaata tggctaacaa tgcgctaaaa agcaatggct atacaccaaa
    10381 cgatgaattg acacatattt tcactgactg gcgcaaaaca cataatcaag gtgtatttga
    10441 cgcttatact gctgaaatgc gtgctgctcg taaaaacaaa atcattacag ggcttccaga
    10501 cgcttacggt cgcggacgta tcatcggtga ctatcgtcgt gtggcattgt atggaatcga
    10561 ctatttgatg gaacaaaaga aaaaagatca tgatatgact ggttatcata caatgagtga
    10621 agaagtgatt cgtttacgtg aagaaatcac tgaacaatat cgtgcattag cgcaaatgaa
    10681 agaaatggct gcgaaatatg gctatgatat ttctaaacca gctgcaaatg caaaagaagc
    10741 tgtccaatgg ctatacttcg gatatttagc agcaatcaaa tcacaaaatg gtgctgcgat
    10801 gtcaatcgga cgtatctcag cattccttga tatctatatc caacgtgatt tggataatgg
    10861 agtaatcaca gaaaaagaag cacaagaatt gatcgaccac ttagtaatga aattacgtat
    10921 ggtcaaattc gcgcgtacac ctgaatataa ccaattattc tcaggattcc ctatctgggc
    10981 tactttatcc attgcaggta tgggattaga tggtcgttca ttagttacaa agaatgattt
    11041 ccgtctgctt catacattaa caaatatggg accttcacca gaaccaaact tgactgtttt
    11101 gtattctgaa caccttccag aaggattcag aacatatgct agcagaatcg ctatcgaaag
    11161 ttcttcgatt caattcgaaa atgataatca gcttcgtgaa caatggggtt ctgatgattg
    11221 tgcgattgct tgctgtgtat caggaacagt tgtcggaaaa gacatgcaat tctttggcgc
    11281 tcgtgctaac ttggctaaaa cactattata tgccatcaat ggcggagtcg atgaagtgac
    11341 tggcgcccaa gttggaccag aatatcgtcc aatcacatca gaaatactag actttgaaga
    11401 agtgaaacat aacttcatga atatgatgga ttggttagca gaactatatg tcaatacgtt
    11461 gaacatcatt cattatatgc atgataaata ttcttatgaa gcagctcagc tggctttgat
    11521 ggattctgac ttgcaacgca catttgctac aggtattgct gggatctctc atgcggcaga
    11581 cagcttgtca gcgatcaaat atgcaaaagt aaaagcaatc cgtaatgaaa aaggaatagc
    11641 agttgatttt gaagtggatg gcgacttccc taaatacgga aatgatgatg accgtgcaga
    11701 tgaattagtt tcatggatct tggaatactt catgggacaa atcaaacgtc ataaaactta
    11761 ccgcaactca aaaccaacaa cttcattatt gacgattact tcaaatgttg tttacggtaa
    11821 aaatacagga aatactcctg atggccgtga agctggaaaa ccacttgcgc caggagcaaa
    11881 tccaagttac aatgcggaac aaagtgggtt attagctagc ctgaactcaa cagctaaaat
    11941 gaattacggc tgtgcattgg atggaatttc aaatacccaa acaatcaatc cttcaggtct
    12001 tggaaaagaa caagatacaa gaatcgaaaa cttgcgtaat gtcttagatg gatacttctc
    12061 aaaaggagct tatcatttga atgtcaatgt attcagtaat gatttattgc gtgatgcaat
    12121 ggaaaatcca atgaaatatc cgaacttgac gatccgggta tctggttatg cagttaaatt
    12181 ccgtgacttg acaagagaac aacaattaga tgtcttgatg agaacttcac acgacagaat
    12241 gtaaaaagtt cgtgaaaaaa gtttttcgac ttagcgtcga aaggacgttg aatagccatc
    12301 gcatcaaaat cgaataatca gtatgcttat ttgaaagaaa cgatttacag gggcaggact
    12361 tgtatgttcc gtccctgtaa attttacaca taacgaagcg gcaattgcga aaaattttgt
    12421 tcagaaagct tcgcttcgac agctaacttg tacttaaaat gaaatcaaag aaaagatgtg
    12481 aacttaaatg gaagaaaaaa caatcggcta tgttcattct atcgaaactt tcggttcagt
    12541 agacggacct ggactgcgct ttgtcgtgtt tatgcaagga tgccgcatgc gttgccaatt
    12601 ttgtcacaat ccagatactt ggaatattgg cggagggaaa gaatacacag cagatgaact
    12661 tttagataaa gcagaacgct tcagacctta ctggggagat aaaggtggta ttactgttag
    12721 tggtggagaa cctctattgc agatcgattt tttgatcgaa ctatttaaaa aagcaaaaga
    12781 gcggaagatg catactacat tggatacatg cggaaaacct tttacgtatg aagaaccttt
    12841 cttttcacgt tttcaagaat tgatgaagta tacagattta ctgttatttg acatcaaaca
    12901 catcgataat gaagagcata aaaaactaac gcattgggac aatgaaaata ttttagaaat
    12961 ggctcaatat ttgtcaaaaa tcaacaaacc ggtttggatt cgccatgtac tagttcctga
    13021 gcgaagtgat tatgatgaat atttgatccg actagacaac tttattcaaa ccttgtcaaa
    13081 tgtagacaga gtagagattc ttccttatca tacgatggga aaatacaagt gggaaacact
    13141 tggtttgaaa tatccattag aagggatcga accacctaca aaagaacgtg tcgaaaatgc
    13201 taaacgattg cttcatacag aagagtatac aaaatattta acgcgatagg tcgcatcgga
    13261 aagaagataa gtattgcttc tttccgtttt tttgctatta ttaaatagga gaaatcacaa
    13321 aggagcgaat gacatgtcaa aaattttagt ttttggtcac caaaatccag atacagatgc
    13381 aatcggggca gccattgcgt tttcacactt gcaaaatgaa ttaggtaaag aaacagaagc
    13441 agttgctcta ggtacaccta atgaagaaac acaatacgca ttagaccact ttcagctatc
    13501 tgcaccacga gtagtagagt cagctaaagc agaaaatgca gatgtcatgc ttgtggatca
    13561 taatgaattc caacaaagta tttcagatat cagcgaagta aatattttag ctgtagtaga
    13621 ccaccatcgt attgcaaact ttgaaacagc taatccattg tactatcgtg cagaaccagt
    13681 tggatgtaca agtacgatta ttttaaaact atataaagaa aaccaagtaa caattcctaa
    13741 agaaatcgca ggaatcatgc tctcagctat catttcagat acattgttgt tcaaatcacc
    13801 aacatgtacg cctgaagatg aagcagctgc aaaagaactt gcagcaatcg ctgaagtcga
    13861 tctaaacact tatggacttg aaatgttgaa agcaggaaca aatctaagtg ataaatcagc
    13921 tgcggttctt cttgatttgg atgcaaaaag tttcccaatg ggcagttcca acgttcgtat
    13981 cgctcaagtc aatacagtgg accttaatga agtgatggat cgacaagcag agctagaagc
    14041 agcaatggaa gatgaaatga aagcaaatgg ctacgatctg ttcgtattag ttgtcacaaa
    14101 catcttagac agtgattcag aattacttgt tgctggtaaa ggaaaagaaa aagtagaaga
    14161 agctttccaa acaactttga ccaacaaccg tgctttgctt aaaggtgtcg tttcacgtaa
    14221 aaaacaagtc gtacctcaat tgacggctgt atttagctaa tcaaatggta gtatgaagca
    14281 ttcaaaatga atggataagc gattgatata aaaagaaaca tagaacatac taaaggccga
    14341 agaaatggag gagaataaca gtcaattatg actcttgttc ttcctccttt ttacgtaaaa
    14401 gccttttaag taaaataaaa cggatagaaa agagaacata tatgaactat tattcaaaaa
    14461 ataaggaaaa cttttatcaa aaactgaccg atgatccgct tttttcttca ttgaccgatt
    14521 atctatatga acatcgagaa caagaaacga ttctaagaga attgaaaaaa gaattttcgc
    14581 aaaataaatt ttcccatttt cttgatttat tgatcgatgc aggattaatc aagagggaag
    14641 aacgaagata tcatttgaac tttccaatat ttgatcctaa agattacttg caacaagcca
    14701 cttcggctgc tgaaaccata gctgaacaat tgaagagact ctctgttgat gaacaaaaat
    14761 tagcgatggg agaagttatt tgggcgtatt gtttcgaaga tgaacggaaa gaagcgtatt
    14821 tttatggagt aagaaacagc cgagagacag aattgctgag gacaactgca ggaaatgaga
    14881 agtaccgttt tatcacactt tcctctatag aacacttccc gcttactttg gctaattact
    14941 tttttgtaca gaagaatcag cttcctgtaa cgaaggcatt caaagaatta gccgaactta
    15001 ttggagacgt aaatgaatcg tacttttttg atcaaataga agttatcgtt gacaggatac
    15061 gtaagaataa atataaaaat cgccggccta gtattttcca tcagtctcta cttgtgacga
    15121 atactataaa ggaagaagaa tcattcacat tagaattacc tattgtcgaa aaaaacaatt
    15181 ttgagattga attaccaaca ttggatcctt cattgacaat ggaggaaatg gcctttctta
    15241 aacgacaaat cttttctgag ctgagcaaga aatttatacc gcatgcattt tcttatatca
    15301 aagaatatgg aacagtttta gtgagtaaaa cctaagagag cagtaagcaa aaattatact
    15361 gactcttgca ggaggagcct ttctcttcct ttatggttaa aagaattatt tgagtatttt
    15421 gcctatctac cacctattag attcactaca tggtctggaa acaaaggaat gcaaaaaaat
    15481 ggtgagaaat gtggaatgac aaaggaagta gtgataagaa aagttagatt tttaaataat
    15541 caatattatg attcagtcaa gtatggcatt ttatgggaag aactagctga ttagattagg
    15601 aagtccattt gataatccag aatcactaag aaacgaatgg cgagtcatta ataatttatc
    15661 caatcttggg ttattctttt agattgaagt gtttaaaact aaaaaagcat ttatgaagtc
    15721 gtaatagtca ggcttcaaaa tgctttttat tttgtttgtt ttttctttgc cacataaata
    15781 cacctagact gacgatgaag agcatatcca acagatttcc tgcgacttgg atcgtcgaag
    15841 ggttggtcag tggcattaaa gcaaggacaa aaaaggaaaa caagctgtaa ataaaacagg
    15901 tgacaggaac taatcgaaag aagagcggac atttcaattg gctaaaaatg agtgaaaaaa
    15961 taaaataagt aaaaatggat aaaatcacga ctaaaccatt catgataaag aagaaaagcg
    16021 tattgtgatt aaacgaataa aaaagaattg ctaaaaaaga aaacgtttta aatgcaatca
    16081 atacgcttga agcttcgttt aacgtaccag gatgtcgatg aaaaaaatag gcaccgaaat
    16141 aaacagaaaa cagtaagccg caaagagaag acaaaatcaa aaaaaacgga ttttcttcgg
    16201 cttctgtgat atcagaatga tccaaaagca accagcctaa tgcactagaa ggcgcatgtg
    16261 aggtcttaag gtatgaataa catagaaaaa ataagatcgt caaagttgca aaaaaagagc
    16321 ctaaatgtaa aaaattagtg gttctacgtt gaatttccat aatatctcca aattaaattg
    16381 ataagtatat aaagtataat aacaaattga tgagtatatg tcgatgtttt ttaatcaaaa
    16441 taataaataa aaactgtcta acatttaaaa tttaatttag atattagaca gtttttaagt
    16501 ttgtgagtta ttttccttgt cgttttctca cttttttagt ccagaaacca cctgaaatat
    16561 attttggctc ataagaaatg ataaaagcac gctcttcgat ttctttgatc aggcgataca
    16621 gttcacgttc gctttttcta ggagaaagta tttcgagaac tagccgctca ccttccagcc
    16681 ccattgcaga agtctgtgtc acaccataac cgtgttctct cagtataccc ggcaaacttt
    16741 tatcttctgc gctatttgct ggcaaaatcg ttgtgaccat gatgtatcct aatgccaatt
    16801 tgtcttcaat caaaattccg acactgatac ctactgcgta acctaacgca tagacaaata
    16861 aattcagtgg attatctaaa cgatctaaaa caagggataa gccgacgata taaatcgtga
    16921 tctcgaccat actgacaagt ggagcaatca gtcgatagcc tttcattgtc aacatgaaac
    16981 gtaacgtgtt cagagtgata taagcaaaat taatgaggaa gatcatcccc aacatttttg
    17041 gatcaatcat ttgtaaaact cctttcattt atataacaac aatatcaaaa aaaatcgtaa
    17101 gtgaagaaaa attgaaactt tatacataca aaaaaatgat aaaatgatta taatagaatt
    17161 ataaagatag gttaggtgat taaaatgaaa acggtcaatc gtgtgttttg tgccagccac
    17221 gtgctaagtc tccttctcag tatatactta ggtgtctatt cgattcaaca gccaattgag
    17281 gtagagaaca ttgtttttca gatgtcgctg acagatggtt taattttaag cgtttttttc
    17341 tttttgatac tgtttattgg taatattttc ggtagcgttg ccagtttttt gaatttttct
    17401 atttatccac tcctttcgct agcattagga gtggtgggac tttgttctct gtgcttattt
    17461 cccgagccat tcagtcctgc atttatatta tttggtacac tgaacctgtt ccagacaact
    17521 gttggagcat ggttgctatg gcgatcagga aatttaatga aaataggtga gtaacaattg
    17581 aatccaatta tattgaaacg ttctgtccat catattccag tgttagaagt tgttctgaaa
    17641 gaattaagag aggaacgtat tcccgttgtc atctattatc acggatggca gacaagtaag
    17701 gagttagttt tgacgcaagg aagaaaaatt gcgcagcagg gcattcgtgt gatcctgcca
    17761 gatgcgatga atcatgggga gcgcaaacag ccggtttctt ctattccatc ctatacattt
    17821 tgggatagta tctacggaaa tctgtttgaa tttgacacac ttatcaagca tttagaaaaa
    17881 agaggtcttc tacatgatca gcttgcagtt ggcggggttt cgatgggggg aatgacaaca
    17941 tgcgccttgt tggctaaaca tcctcatata gtagcgggcg tgtgtttgat gggttcccct
    18001 gcacctttgg aatatggaaa agaaatcgta aggcgcgcat cggaatataa ttatgtcgta
    18061 ccaaaagact attttgattt gatttcatgg gttaagagct atgatttgtc attgcagccg
    18121 gaaaagttag ctggacgtcc tctgttcttt tggcatggac aagctgacga aaaaatccct
    18181 tatatacaaa cggaacgatt tgtagaaaaa aatcggcata agtcttacgg aaaagaaatt
    18241 gtttttcgtt cctcaaaaac acagcgacat atggtacaaa taccactaat ggaagaagct
    18301 tccacttttt tagcaaaaaa tttgataaaa aagtataaat aattgaaacg gaaaatcact
    18361 catgacgata gaggattttc cgttttttat tttgggctat aataaactct gttaggaaaa
    18421 tttggtataa ttgatagtaa gaatgacaac atgttagaaa ggaagagagc atgcccactt
    18481 tagcagatgt tgcaaaacgt gccaatgttt caaaaatgac ggtctctcga gtcatcaatc
    18541 atccggaaca ggtgactgac gaattgaaag agttagtttt ctcagcaatg gctgaactgg
    18601 attaccgtcc aaatattgct gcaaaagcac ttgtcacgaa tcggtcgcag atcatcaaat
    18661 tatttatact ggaagaaatc gacacaactg agccctatta catgaatttg ctgatgggaa
    18721 tcgctaaacg gatcggtaaa gcgcattatt ctctccaatt agttacaaat gatgccttcg
    18781 acgtcggttc ttgtgatgga tacatcatca caggtgtcag aaaaaaagac ttcgattgga
    18841 tcgaccgttt ggaaaaacca gttgtcttgt ttggggaaaa ttctgaagga tatgattatg
    18901 tagacagcga taatgaatat ggtacagcaa aagcaacgca atatgcctta gaaagagatt
    18961 atcaaacgat tatttatatc ggtatcgaag tggacgagcc ttttgaaatt tcaagggaaa
    19021 ctggttattt atctgtgatg aaggaagttg atcttcctag taaaatcttg cggtttccaa
    19081 atcattcgac agaagtagaa agatatatga cagaaaactg ggcagatttt acagataaaa
    19141 cttgttttgt atgtagttca gatcggctag cactaggagc agtaagaggg attataaatg
    19201 ctggaggaca cttgcccgaa gaatttggtg tgattggatt tgatggggta tttttagacc
    19261 aaatcagttc acctaaattg acaacgatca agcaagatat tatacgtatg ggtgaagtat
    19321 gtggagaaat gttgttaaaa aaaatagaag aaaaaggggc gagtcaaggt tatcgtcgtt
    19381 tttttcctga actagttatc agagagacaa cgaattaagt cttattacta tatatatatt
    19441 tatgaaattc atcgctattt tcttaaaata atcagcgcat tgctactgaa aacaatgaat
    19501 ctgtgctatt attgagaaaa gttccatttt tgagaaggat ggtttgaatg aaagaaatca
    19561 gacgaaaaca tttccgtttt cctgcgtacg atgatgagtt aggcgtaaaa ttaaccaacg
    19621 acaagaagcg agtattattt gacggacaag aagatctttt gactgaacag aatcagtccc
    19681 cgtttgaaca gatgaaagaa tttcatttca cgaacacgaa caccgagaaa atccgtcgca
    19741 agcgtcgtgc aacaaatgga ttgaagtcag ctccgcgtaa ggaaaatttg gaaaagcata
    19801 aaggaaaatt accggattat accggccatt accaatcaga aatcacatcg acaggacgaa
    19861 aaaaactttt tggtgattcc tctcgttctg tcagacaaag tgaaacaagg acagagtcca
    19921 agcatactac acgaaacgca tctgttgaca cgaaggtgcg ggagcgttct tattttgttc
    19981 ctaaatatgt acccgcatcg attatcccag accctagaga aagcaaaatt tctgaggatc
    20041 atttaatcga atcgatgaaa aaaacggatg actcttatct gttgttcgat acagaaccga
    20101 cgccgtatca agaaaaaaga aatggtgagc cgtctgtacg aacattcaat cgaacaaaaa
    20161 cgttagagga aacaaagcag tcagaagaaa aaaaatcgaa aaaaagccat ggtatcttag
    20221 aacgctcatt acaaggattg atcgatgatc aaggaaactc tttgggagaa aatagctatt
    20281 ttaaataagt gatatacaaa tttatattcg gctacagttg gaaaggaaac gctgcggcgt
    20341 ttccttattt tatactctat ccgaaagttt atatcgtatc ctcaaatttt tttgagttta
    20401 agcgaatttt ttctcccaat aagtaagaaa ataatggcaa aataaaaaaa caaactattt
    20461 tcgcagatcg tttgcaaaaa tagtt
//
LOCUS       DARBDN010000047        19007 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000047 DARBDN010000000
VERSION     DARBDN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.047"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(70..279)
                     /locus_tag="SCH06_001643"
     CDS             complement(70..279)
                     /locus_tag="SCH06_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078208.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(290..1618)
                     /locus_tag="SCH06_001644"
     CDS             complement(290..1618)
                     /locus_tag="SCH06_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078209.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            1754..1909
                     /locus_tag="SCH06_001645"
     CDS             1754..1909
                     /locus_tag="SCH06_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078210.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(1983..2570)
                     /locus_tag="SCH06_001646"
     CDS             complement(1983..2570)
                     /locus_tag="SCH06_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEG1078211.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(2653..3903)
                     /gene="clpX"
                     /locus_tag="SCH06_001647"
     CDS             complement(2653..3903)
                     /gene="clpX"
                     /locus_tag="SCH06_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEG1078212.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVFNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(4150..5439)
                     /locus_tag="SCH06_001648"
     CDS             complement(4150..5439)
                     /locus_tag="SCH06_001648"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEG1078213.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(5593..6525)
                     /locus_tag="SCH06_001649"
     CDS             complement(5593..6525)
                     /locus_tag="SCH06_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078214.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(6682..7341)
                     /locus_tag="SCH06_001650"
     CDS             complement(6682..7341)
                     /locus_tag="SCH06_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEG1078215.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(7344..8369)
                     /gene="sppA"
                     /locus_tag="SCH06_001651"
     CDS             complement(7344..8369)
                     /gene="sppA"
                     /locus_tag="SCH06_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEG1078216.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(8382..8672)
                     /locus_tag="SCH06_001652"
     CDS             complement(8382..8672)
                     /locus_tag="SCH06_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078217.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            9081..10886
                     /gene="glmS"
                     /locus_tag="SCH06_001653"
     CDS             9081..10886
                     /gene="glmS"
                     /locus_tag="SCH06_001653"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEG1078218.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(10958..12313)
                     /locus_tag="SCH06_001654"
     CDS             complement(10958..12313)
                     /locus_tag="SCH06_001654"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEG1078219.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(12337..13506)
                     /locus_tag="SCH06_001655"
     CDS             complement(12337..13506)
                     /locus_tag="SCH06_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078220.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(13503..14390)
                     /locus_tag="SCH06_001656"
     CDS             complement(13503..14390)
                     /locus_tag="SCH06_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEG1078221.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(14579..18271)
                     /gene="nifJ"
                     /locus_tag="SCH06_001657"
     CDS             complement(14579..18271)
                     /gene="nifJ"
                     /locus_tag="SCH06_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HEG1078222.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            18470..18991
                     /locus_tag="SCH06_001658"
     CDS             18470..18991
                     /locus_tag="SCH06_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEG1078223.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         5317 a         4087 c         3381 g         6222 t
ORIGIN      
        1 agtcaaaaaa aaataaaaaa ccagtcagaa agactggttt tttatttttt tgtctatcat
       61 caagccgttt tatcgttttt tattttcgct tcttgttttt ttcatataaa cagaagcagg
      121 ttttctttcc ttatgaagaa gataataata aagtcccatc ccgccaaaca tgaccaaaaa
      181 accgatgact gatcgaatag gaaaattagg aacaaaaaag agacagacgg ataataatga
      241 tgccggaacc attattcgat aatagagttg tttatccatt ttcttcacct catatttttt
      301 gtaaagtaat caattgttct aattctcggt aatctaaaaa ttgcacacgc agatgctgct
      361 cacctttctt gacatcgaat tggatacttc gccgcttttt ctttattcgt ttgaaggtaa
      421 catcagagag tctatgtttg atttccttta acggtaattc tgacagggat tctgaaggaa
      481 catagattct taaggataaa agatactctt gatatttttc atctgttacc tctacttcta
      541 gatattccct aatataataa caataagctt cgattccatt atccaaagca acagtcggat
      601 cgataacttt atagcacatc atgcgtgatc gattctcgtc aacccaagga aaatacgcct
      661 gagcatttag tgttccgcga acacgccttt ctttataatc tccttgttgg atatcataac
      721 tttttgttac aaaaaatgaa gcattctttt taggaacagg ttgcatttgt gcattctgat
      781 actggacaga ttggatcgta tggtcagtgt aaatgtattc aacgaatggc ggtttcaata
      841 aaccgacacc attgtcccaa gcaagatgat caaacccaag ctggtcccta aaataggatt
      901 gaaacatttg attgtttggc ttttgccagt taaaggggtc tcgataaagc tggatacata
      961 tgacttcgtt ttctaattcc ttcacttttt ctacttgttg gatgtcgaga aaaatcggtt
     1021 tagggatgat ttgatgataa tagcgactat aatacatttc ccaacacgaa gtgaaacata
     1081 aaccttggta aaaaagatcg tatcctggaa attggttgca atcgactact acttccccgt
     1141 tttgttgttt cattttaggt aaatgttcga tttcatcctt tttctcaaac aatagccgtt
     1201 gagagatctg ttttgtattg tgatagataa actcgctata agctcgcata taggcgaaca
     1261 ccccatgagc aatcattttt ttctgaatga agtctcgaat caaaaattgc ttttctttga
     1321 aaacagagat agacaataca ttttttatca ataattgatt atcttccaag cgaaaactac
     1381 attcgttctc gtcatttcct acaactaacc aactttcgtc tcttaccgat gctagcatta
     1441 ttttttcttg aagctttcga agatcatacg gatccgcttg ttgtgtgaaa gagcggataa
     1501 atgttggctg gatcaacaga cgtgtcaaaa tagcccaatc gcttatttcc tgtttttttt
     1561 cttcttcatt taagtctgtg agctggatag tcatcaataa tttatcttcg ccaatcattt
     1621 tctcacctct ttcaaatctt tttataattt aattataacc aatgataaag aaaaactaaa
     1681 actttatgtc ttagaaacca atttggacga ttacatgata gactaagtaa aaagaaacaa
     1741 agaggtgttt acaatggggt tgaaatttga acgtacagat aatttagata aacttttcga
     1801 atcatttgct gtcgatccgg aaaaaacagt tgcaccaaaa gaagagatcg atcgatttct
     1861 aaaaccacag ccacaaaatg aaaagaaaaa agacaagaaa caaaagtaag ttaagctcaa
     1921 aaaaagactt accagccaaa cttttatgaa agagtttgac tggtaagtct tttttattct
     1981 ttttatgatt caattgcttg ttcgattgct gcccacgctt cttcttttcc ctgttttgta
     2041 acggaagaaa agagaataaa cgtgtcattg cgatcaaaat ccaacgcttt tttgatttcg
     2101 ctctcatgct tgttccattt accacgaggg atcttatctg ccttagtggc aacaacaatt
     2161 acagggatat cataatactt caaaaattga tacatctgga tatcttcttg agaaggctta
     2221 tgacgcaaat ctactaaaga aacgaccgca cgtagctggt ctctagtcgt taaatatgtc
     2281 tcgatcatct ttccccattt tgctcgctca gttttggata cttttgcata cccatatccc
     2341 ggaacatcga caaaatgtaa tgcgttctcg atcaaataaa aattcaatgt ctgggtcttt
     2401 cctggcttac cggaagtacg ggctaaattc tttcgatcaa tcaatgtgtt gataaaagaa
     2461 gatttcccta catttgatcg tcctgccaga gctatttctg gcaattgtgt atctggatat
     2521 tgttttggtg ccactgcact tatgataatt tcagcttgat ggactttcat ggtctctctc
     2581 cttaacaagg tgatgaataa agcaagcggc tgtcgcaaaa gccaaaatga cttttacggc
     2641 agcctctttt catcaacccg cttttttctc tgaatcttta tagattactg ttggctcacc
     2701 agacaattca gctgcttctt ttgtgataat cactttttcg atgttttcat ttgaagggat
     2761 atcaaacatc acatccatca tgatttcttc aatgatggaa cgaagtcctc gagcaccggt
     2821 attgcgttcg attgcttttt tcgcaatggc tctcaacgct tcaggttcga attcaagttc
     2881 ggtattatct agagaaagaa gtttttgata ttgtttgact agcgcatttt tcggctcagt
     2941 caagatccgt accagatcat ctgttgtcaa tttctctaaa gctgccataa caggtaatcg
     3001 tccgataaac tcagggatca atccgaattt tagtaaatct tcaggaatga tatgctgcat
     3061 gacactttcg tcttcagaaa gtttttggtt ttgtgtacca aatccaatcg tcttttcgcc
     3121 catacgattc ttcacaatcg tttcgatgcc atcaaatgca ccacctacga tgaacaatat
     3181 gttcgtcgta tcaatctgaa taaattcttg atgtggatgt ttacgtccgc cctgaggtgg
     3241 cacacttgca acagttcctt ctagaatttt cagcaaggct tgttggacac cttcgccgga
     3301 aacgtcacga gtaatagata cattttcgct tttacgcgca attttatcga tctcatcaat
     3361 atagatgatc cctttttctg caagttccac attgtaatca gcagattgaa gcaatttaag
     3421 caaaatgttt tctacatctt cccccacata accagcttct gtcaaacttg tcgcatctgc
     3481 gattgcaaaa ggtacattca atgtttttgc taatgtttgt gctaaaaatg ttttaccaga
     3541 ccctgtaggt ccgatcaagc agatattgct tttttgcagt tcaacatcat ctgtgttttc
     3601 ttgtgcttgc tgattgacac gtttatagtg attgtatacg gcaacagcta acgagcgttt
     3661 tgcgcgatct tgtccaatca cgtagttatt aaatacttca agaatttcta gtggtttagg
     3721 gacttcagtg aattcgcgta cagcttcttc ataaaattct tcatcaatga tttctttaca
     3781 taggtcgata cattcattac agatgtagac ccctggacca gctacgatct ttttcacttc
     3841 ttcttgggtt ttcccgcaaa aagaacagcg tacggtctca ttgctacttg gattgtcata
     3901 catggtcttc accccttaac ttgcaaaaag tatgcaagaa actatcaaag actttacagt
     3961 cttttactat cataacatag tttagtaaaa agaaaaagtg tttaacaaag gatcaactga
     4021 cctatacctt tgcatttttt actcttaaca aaaaataagg aactgtgaca aaatcgtgtc
     4081 acagtccctt atttcgaata aacaattttc tagaagtagc ttcttcagaa atgatttatt
     4141 acttgatttc tattctttcg cttctgtcgc tgtacctgtg atcaattcga ttgctttttt
     4201 cattgtcaca tcatgttcca gcatatcttc tgtcaacacg cgtttgattt gttcgattgg
     4261 catgttgtat gtttctgata attcttggat ttctgcattg atttcttctt ctgttgcttg
     4321 aagattttca gcagctgcaa ttgcttcgat cacaagattt gttcttgtgc gcatttctgc
     4381 ttcaccttcg aattgtttat gcaagtcttc ttctgtagaa ccagttaatt gatagtacat
     4441 ttcaggagag ataccttgac gttgcatgtt gttcaagaat tcgtccattg aacgatgtac
     4501 ttcatcatga accatcacgt gtggcaattc aacgatttct gcgttttcaa cagccatacg
     4561 gatcgctgct tcatcttttg catcgtccgc tgctttttct tttgtttcta ctaattcttt
     4621 gcgatatttt tctttcaatt cgtctaatgt tgatacttcg tcatcaacat cttttgcgaa
     4681 ttcgtcatct aattcaggca cttcttttgc ttttacttca tggattgtca ctttgaagac
     4741 tgcttctttt ccagcaagat cttctgcttg ataatcttct gggaaagtta catttacatc
     4801 tagactttca cctgatttat gaccaactaa ttgatcttca aaacctggaa tgaatgagcc
     4861 tgaacctaat tcaagtgagt aattttcgcc ttttccgcca tcaaacgctt cgccatctac
     4921 aaagccttcg aagtcgatta ctactgtatc gccattttca gctgcagcat cttctttgat
     4981 aactaattca gcttgtgctt cttgttcacg tttgatacgt gcatccacgt cagcatctgt
     5041 tacttcacgg tcttgttttt caacaactag atctttatat tgtcctaatt ttacttctgg
     5101 tttcactgtt acttcagcag tgattaccca gtcttgacct ttttccatgc tttcaacatc
     5161 gatttttggt tgagaaacag gatcgatgcc agcttctttg acagcagctt cataagcttc
     5221 tggtaataca gcattcaatg catcttcata taaagcttct tcaccgtaca tacggttgaa
     5281 tacttgacga gaaactttcc ctttacggaa tccaggtacg ttcaagcttt ttttcacttt
     5341 attaaacgca gttgttaatc ctttttggat ttcgtcttgc gcaatcgtaa attttaaaac
     5401 accatcattc gtgccttttt tttcaaatgt tgcagtcatt taattccctc cgagtttaga
     5461 aattcatttt atacatcaaa aacgtttcat gcataccttt aaatagtaca ctaacccttt
     5521 caaattgtaa acatattgaa tggatagaat ccttgttttt cataacattt ttatcttttt
     5581 cactgataaa atctaatgga agaagatcat ttgctgcaaa attttttctc ttttttttaa
     5641 aaaatcttgt ttttcatctt ctgtaccttc atacatcgtt tttcctgtac acgcctctac
     5701 agtcagttga aaccagcgct tcgggtcttc gatgtatgta tcatagacag gataaacaat
     5761 tgcagattgc aacgtgaatt cttcttttaa cacggaacta agcagcgcat cttcattccc
     5821 gtaacgatct gaaaatacac ataattgctg gtaacttgcc tgctgctgcg gctttggcag
     5881 atcttttggt atgactttga ctaacttttc ttcaatcgtc aaatagaaaa caggatggca
     5941 ttcgttcaat tgcctaagtg tctccagtaa ttttgccctt gctaaaatat ggacctctgg
     6001 cgatacaata agtttactcg ctgtttggat aaactcatga taaggaagct gttcgatctc
     6061 atcaatagac gcaagctgac gtgcaggttc caacgaagga agttcctccg atttattgtg
     6121 gagtgccttg atcttctgcc tctccatttg tccggataat tcttctgcaa attggatttt
     6181 ttcaatgacc cgctgctcga aagcttcata aaaatctgta cttgctatca attttctagc
     6241 atataaaaaa tcttgtgtac tgattaacaa gtcaaaataa aattcagcaa actcctcatt
     6301 ttgaagatac tgtttttcat gcaagagtgc ttgcttcaat gcttcttttt tctcgtccaa
     6361 ctcgtaaaga caaaaaacaa gcaggctatt agcctcaaag ctttctttca actcgtaagc
     6421 tcgttgaaat aattcttttg cctgctgata ttgctggttt gctagtgctt gttgtgccac
     6481 tcgcattaaa ttctcatatt tttctggaaa atcaatcggc ttcacgcagt gtcctcctct
     6541 tgctcatatt cagctcatgt tcaatagtag caaaacaaaa aaagcatgac aattaaaaat
     6601 aactgaagca ccctctaaaa gctagatttt agatctgact tttagaaggt gctttcaact
     6661 gttactgctt tttattgctc atcagctgtt gacttcctgg ttgaacgctt tgatcagatt
     6721 gatcgtaaca acacttgtat tagtgaaaaa atcgcccaga tgttgctttt tctgattaaa
     6781 gactgctgga agatacccta acatcagcaa aggaaatttt agaatgaacc ggcaagcacc
     6841 ttctctaact aaaacggttg accagctaag ttcttcttca tcaaagctga tgactcgaat
     6901 accaaagatc attttcccaa tcgtttggcc atgattgaat ttcgtcaata aaataaaata
     6961 cgctagataa ataagtaagg ctgtgaatcc gtagagactc agataagaat ctgaaaaatt
     7021 aagccaacct agatttttgg caataccaag tgttaaacgc gtaatagctc cgatacacaa
     7081 aagatcgacc aagaaggcaa acattcggat aaaaaaacct gcatagaaat acttaggaaa
     7141 atcatttgct tttggcggtt catttcttgt gtccgtatac tttttccatt tacgttgttt
     7201 ctttttgatt tcttcgggcg tcaaaggctc tctttcaaaa gagctcagta ccttttggga
     7261 aaagttggag tcaggtccta cagcaggctg ctgttgctta tctttttctt gttccttatt
     7321 ttcatttgaa agctctgaca tgcttactca cctccgtaat aatacattgc ttttggtgat
     7381 tccgctgtcc ctagattctc aagaacggat aagatctgac tagtctcaga aggcttcaat
     7441 ccctggaatt ctgctagttt acttcctaac catgtactag caaacccaga tggcgtggaa
     7501 gaatattcta ctagttccgc atcttcaagc tgttgttcct ttcgtatagc ttttaaagca
     7561 tcttcaggaa atcccaattc atcgactaaa cctacttctt ttgcttggac accatcataa
     7621 atccttccat cagcaatttt tttgacttct tcttcagatt tattccgtcc ctcgctgacg
     7681 attgctacaa aacgactata tgcgctgtcg atatatgctt gaagcaccgc ttcttcttct
     7741 tttgtctctg gtcgcgttcc tgaacccata tctttcaacg ctccgctttt aactgttgta
     7801 tcttccacac ccagtttttc tagaagtcct gaataattca atcctgacat gatcacacca
     7861 attgagccgg tcactgtttc ttctgttgca aagattttat ctgcttgagc agaaatatag
     7921 tagccaccgc tagctgccat gtttttcatg ctgacataca ttgggatatc atgttcttta
     7981 cgaatcgtat ccaatttctt agcgatttcc gcactttcgt agacaccgcc accaggagaa
     8041 tttacttcta aaaagatacc tttgactgtt ggatcttctt caatcgcctt cagttgttcc
     8101 ataaaatttt tatgattgta accttcagaa gcaaataaac ctgaagaccc tcccgcagca
     8161 atcgttccat ctactgataa ttttacgatt ttttgcgtac tgtctccctc ttccaacaca
     8221 tttggagcta gttcttcatc cccatataac caactgttca atccctcaat ttgatcgttt
     8281 tcctgaggct tagtcaaact agctgaaact aacgaaacca caaataatcc tgcagcaatc
     8341 agaactgctg cccaacgtct tttattcatt ctttctcctt tctaatacaa gttttttatg
     8401 acgatcacag tttctgactg ctcagaagtg tcgaaccgct ctgctttttc ttcccgcgca
     8461 tacccggaaa acgactcttt tgttaattca tcttctaccg taaactcacg agcttgagca
     8521 acttccaagg catcaggtgc gatttcttgg atgctatccc agccagtatc taaaaatatt
     8581 ttcgtatcat ctgatacacc agctgatgct tcgaatttgg acaattgttt ttttaacatt
     8641 cccagtgtca tgatctcaat ttttgaatcc atttttactc ctcctctatc cgattacttt
     8701 ctattgtacc gaactcctga aaaagatgat agataaaaac ccattatttt ttgacataaa
     8761 aaggacattt gacaaagaat ttgatatata ccaatttatt ttttattctt tttttgttga
     8821 caagaacatt cgcaaaaggt tatgatttta aatgtttcca gataaaaaac aaaaaggagg
     8881 atagttatac cttttaggat agcgccaggt ctgtgtaaac agatgacgag gagagggttt
     8941 atcgaaagat tcggcggatg gccctaggga ctgcactcta cagaaaatcc acaaaaaatg
     9001 tctgcaaaga taaaacaaaa ggattttcct gcagctggaa gcattcatac gaattcatta
     9061 tagaaagtag gatgtttttt atgtgcggaa ttgttggaat gattggatta aaaaatgtaa
     9121 caccaggatt gattgacggt ctagaaaaat tagaataccg tggttatgat tcagctggta
     9181 tctttgtctc agatggcaca actgattatc tggtcaaagc acaaggcaga attcaaaatt
     9241 tgaaaaacaa aataaatatt gatactacag gaaatatagg tattggtcat acacgatggg
     9301 caactcacgg gcaaccttct gaagaaaacg cccatccaca tacttcccaa agtggacgct
     9361 tcgtgctcgt tcacaacggc gtaatcgaaa actttgaaga acttaaaatt gcttatttag
     9421 caaatgacca ctttattggt gagaccgata ctgagattat cgctcatcta attgaaactt
     9481 tcgcgaagga tactacaacg caagaggcgt ttttaaaagc tttgcgggtc atcaaaggtt
     9541 cttacgcttt cgctttgatt gatcggacag cacctgatgt tatttacgtc gctaaaaata
     9601 aaagtccact attaatcgga ctcggcgatg gattcaatgt gattgccagc gatgcaatgg
     9661 ctatgcttgc tcatacgaag gaattcgttg agattgaaga tgaagagatg gttaccgtca
     9721 catcagaaaa agttattatt caaaattttg caggtgacat cgtagaacgt tcttcattcg
     9781 aagcacaagt agatgcttca gatatcgaga aaggtaccta tcctttttat atgctgaaag
     9841 aaatcgacga acagcctatt atcatgcgtc gtatcgctca aaaatacgta acagaagaca
     9901 atcgtgtctc tcttgatcaa aagctggtcg atacattgtc tgatagcgat cgaatctata
     9961 tcgttgcttg cggaactagt taccatgcgg ggttagcagg taaacagact ttggaaaaat
    10021 tgacacagat tcctgttgag gttcatttag ccagtgaatt tggctataac acacctcttc
    10081 tttcaaaaaa accattcttt attttcttga gtcaaagtgg cgaaacagca gacagccgcc
    10141 aagtgctggt aaaaatcaac cgtctcggct acccttcact tacgattaca aatgttgctg
    10201 gttctactct ttcgcgggaa gcatccttta cactgctatt gcatgctgga cccgaaatcg
    10261 cagtagcatc aacgaaagct tatactgcac aaatagctgt actaacttta ttagccaaag
    10321 ctatcggtga taaaaaagaa tttgaaactt ctcttgtatt cgatatcact catgaattga
    10381 gtttagttgc taatgcgatg gaatcggtca tcgcccaaaa agattattta gaagagttgg
    10441 cagaagtata tctcagcgat acaagaaatg ccttttacat tggacgtggt gctgactaca
    10501 acgtttctct tgaagctgct ttgaaattga aagaaatcag ttatatccag gcagaaggtt
    10561 ttgccgctgg cgaattgaaa catggaacga ttgctttgat cgaagaagga acaccagtga
    10621 tcggaatcat cagtgaagaa gtgactggtg cgcatactcg aggaaacctg aaagaagtcg
    10681 aaagccgtgg cgctaaaaca ctagttattg tctcagaggg attagaaaag gaaagtgacc
    10741 agctggtgct accaactgtc cacccttatc taactactct aaccacagtc gtaccgactc
    10801 aattacttgc atattacgca acgctattac ggggattcga cgttgacaaa ccacgtaatt
    10861 tagcgaaatc agtgacagta gaataataaa agaacaagga ccagtgtcag acatctgaca
    10921 ctggtccttg ttcttttatt ttttatgaaa atatctctta atccagtccg atttcttctt
    10981 tgactactgc cgcgatttta tcgacatagt aattaacttt ctcatcagta ggcgcttctg
    11041 ccatcactcg aagtaatggt tctgtaccgg aaggacgaac taggattctt ccttctgatc
    11101 ccatttcagc ttctgcctct tcaatcactt ttttgattgc cggaacatcc atcgcaccgt
    11161 ttttatcact tacgcggata ttcactaatt tttgcggata gattgttacc tctgctgcaa
    11221 gctctgataa tttcttacct gtctgtttca tgatattcag taactgaatt cctgaaagca
    11281 tcccatctcc agttgtgtta aaatctaaga aaatcatgtg cccagactgc tcgccgccaa
    11341 agttataatc gtttttgcgc atttcttcta caacgtaacg atcaccaact tgtgtaacga
    11401 catctttcaa accgattcct tccaccgctt tgtggaatcc taagttactc atgacagtcg
    11461 taacgatcgt atcttttttc aatcgatttt tttctgccaa gtatttagca cagataaaca
    11521 tgattttatc accgtcgaca atgtttccaa gttcatccac cgcaataata cgatcgccat
    11581 cgccatcgaa agctagtcca gcatctgctc ctttttcaac gaccatctca gctaaacgtt
    11641 ctggatgggt agagcctacg ccgtcattga tatttaaccc gtctggattt gtgcccattg
    11701 tataaaaatc tgtttcaaga tcggcaaaca aacgattaac acttgttgaa gttgctccgt
    11761 ttgctgcatc gacacaaatg gtcaaaccgg aaaggtcacc gttgatcgtt tgtacaagga
    11821 attgagaata tttcaataag ccttctggaa attcttctac agttcccaat ccttcagctg
    11881 atggacgagg caattcatcc acttcagcat ctaataatgc ttcaatttct agctcttggt
    11941 catctactag tttaaaacca tctgcaccga aaaatttgat tccattatct tgtgctggat
    12001 tatgagaagc agaaatcatg acccctgcgc ttgctttttg caaacgtgtc agataagcaa
    12061 cacctggtgt agagatcaca cctagctgga acacttcgat acccaccgat aaaagtcctg
    12121 aaatcagcgc ttcttctaac atttgacctg agattcttgt atcccgccct actaacacgc
    12181 gtgggcgttt tccttcttct tcatgctggc ttaggacata acctccgcac cgtcccagct
    12241 taaatgcaag ttctggcgta agttccttgt tggcttcacc gcgtacgccg tctgttccaa
    12301 aatatttacc catagttgta aaattactcc tttaacttaa ttttctgagg aatttgttct
    12361 gctcatttgt gttgattcgc ttgtttctga tgtttcttct gtacttgtgg tcgagctgct
    12421 tgtcccagat tccgaactgg aagaaatggt tgttgtcgat ggttccgttc ctgaatcagc
    12481 agatgaaata cttctactcg tacttgtatt ttcttgtgtc cgactgctcg tcgaagcaga
    12541 gctactgctt gacgtttgca acacgggtgt aatctccaca ctaactgatt cgggcttgat
    12601 acttaacccc tcttctactg gtatttcaat tttacgagtt gttcgatgat tgatacctga
    12661 gacattgatc ggtacagcaa tactgtcacc gatcgatgca agcaaatcgc tagagccgct
    12721 tacttctgct tccagttttg aaaaactgaa atcatagctt tctaccccgg cagctggtgt
    12781 tccttgctgt atcccataaa gtcgtaccga cttgcttggc ttgatcgaat cagctctcac
    12841 tgttacttgc actggatcag agacgatact taatacttcc cctgctgcat tcagcgcctg
    12901 tattgggacc tcactattaa tcccatcatc tgtgaccatc gaagcgtcca catcagctac
    12961 tactcgtttg atttctgcca atgttttgtc acctgtagtg atagagactt ttttaggact
    13021 aacggaagta tcatcaagtt catatccaga tggtgtgaac gttgaaggaa tcaacgtttc
    13081 cacatcgaaa tcttttatta cctttttctc aaccgttact gtaatagtcg atggttcgat
    13141 ctttgctgtg acagcactgc tcaaattttg aatttttagc ggaacttcat gtgttccttc
    13201 gcccagctta gtgatatctg ctgtgacgcg gaacatccgt gtatcttcgt ttgcctctgc
    13261 attcaactga actcggtttg cactggaaag tttgacagtc actgcatttt catatccatg
    13321 gatatagtag cgctttgaat cataagaaat cttgatcggc acccccgtaa ctgtttgatt
    13381 atacgcttca tttccagaaa gcgtatttgg aacggactgg ccatttgcat tgaagtacag
    13441 cgcaatactg aacagcaatg caataaaact gtaaagaatg cttgtccgtt tctcttttga
    13501 gatcatttgc gatcccctcc cttagtcata ccgtctagga aagattgaat cacgtttttc
    13561 ttgttttttg ttttctcttc agcaattagt tctctacgca agattgccaa atattcttgc
    13621 tgggataagc cagccatcag ttcattatct aacgtgatgc tgacgtcccc ggtttcttca
    13681 gagacaacga tggtaatcgc gtcactgact tcgcttatac cgacagctgc ccggtgtcga
    13741 gtcccgaatt ctttagggat caacatactt tctgatagag gaagataggc gcttgctact
    13801 gcgatctttc cttcttttac aataactgca ccgtcatgca gcggtgtatt aggaataaag
    13861 atattgatca gcagctcccc agtgatatct gcatctaaag caatccctgt ctcaatatac
    13921 tcatctaatc cagtatgacg ttcgatagtg atcaacgcac cgatttttcg cttggacata
    13981 tattggatgg ctttgtcaaa agacaagatc atcttctcat cttcctgctg ttcgcttttt
    14041 gattgtttga aaagcgaact gcgtccaaga tgttccagtc ctctccggat ttccggctga
    14101 aaaatcacga tagcagctat caccccgtac gtaatgactt ggttcatcag ccaagacaag
    14161 gtgtgcagac caatgatttc cgctacgatt cggataacaa taaaaatagc tacacctttc
    14221 agaagctgaa tcgcttttgt gcctcgcagc agttggatca gtttgtatac aagataccag
    14281 acaaccagaa tatcaagtat gttcaccaaa aaattcagag agaacaagtc accggaaaac
    14341 atttgctgcc aatagtccaa attaaaaagt tccccgattt gaaatgacat aaaaagcctc
    14401 tcttctcttt tgagatttcc tctctagtat atcatatgtt ttaattttag aggctgatat
    14461 gctcgtattt ttcttgagaa aaacgcataa ttttcaagaa aattgcaagt atgcgtttta
    14521 tttttctctg caataaatat ttttaaactt cagagaatta ttcattatat tttttctgtt
    14581 atttttcctt tttttctttt gtagcttgtt ccattttttt acgtcgttct gctctggcag
    14641 ctcttctagc agctcttctt tcttctgctt caaggtccgt cgttttttct tttctagtct
    14701 taacgggtac atcgatagat tcctctggtt caagtcgttt cttgattttt tctaattctc
    14761 ccgtcagtgc agcatagttg taaaaacgtg ttttagcgtc gtggacagtc ttttcaaata
    14821 aagcttttgc aagatttgga tttgcgttat ctagcgagga aaagcgaact tgtttcctca
    14881 tgaaatcagg catagcagag aaatcaggtt ttttgtagtc caaagtcatt gggttcttgt
    14941 ttttttcgac cattgtaggg ttatatcgat ataatgacca ataaccagaa gaaacagctt
    15001 cttttgcttc tttaagcgat tctttcattc cgccaagcaa gccatgtgtg atacaaggcg
    15061 tataggcaat aatcagagaa ggaccaggat acttttctgc ttcttcaaat gccttgatcg
    15121 tttgcatttg attggcacct gaagcaattt gcgccacata aacatttcca tatgtcatcg
    15181 ccatcattcc tagatctttc tttgaagcat actttccact agccgaaaat ttagcgattg
    15241 ccgaagctgg tgttgctttt gaggtttgac cgccagtatt ggaatagact tcgttatcca
    15301 aaacaaggat attcacgtct gctccgctgg caagtacatg atcgatcccg ccaaaaccaa
    15361 tgtcgtaagc ccatccgtct ccaccaatca tccattggct gttttttacg aatagatcct
    15421 ttctcttgta tatatcctcc agttcaggga aaattgatcg ttcgctttcg atcgcagctt
    15481 gcagttttgc tgctctttgc tgcgttcctt cactctcaaa catgtgtact aaccagtctt
    15541 ccatcaattc tcgtagttct tctgatactt ttggcaatac ttctttgatt gaacttgcca
    15601 aagcctcgcg acgagtctgt gccgctagaa gcataccata accaaattca gcattatctt
    15661 ccaataaaga atttgaccat gcaggccctt gaccacattc attggtcgta taaggagaag
    15721 caggagaagc accgccccaa atagaagaac agcctgtcgc attcgcgatc atcattcgat
    15781 caccgaacat ttgtgtcaat aattttacat aaggtgtttc gccacagcct gagcaagcgc
    15841 ccgagaattc aagaagcggt tgattgaatt gtgtagacaa gacagtattc tttcctttga
    15901 ctggatttgc tttttgtctt aatgtcattg caaaagccca attcacagct tgttctttct
    15961 gttcttcata aggcttcatc actaaagctt tttcttttgc gggacaagcc tctacacaca
    16021 gaccacaacc tgtacagtct tccactgaaa cttggatacg gtattttacg ccgtctgcgc
    16081 ctcgcatttc tctcacgata aatccttctg gcgcttcttc catttcctct tcatctgcta
    16141 aaaatggacg gatggcagca tgaggacaaa caaaggcaca ttcattacac atcgtacagc
    16201 gatcactaat ccactcaggt acttctaaag cgacgccccg cttttccata gaagccgttc
    16261 ctaaaggcat ttcgccagtt gtcattccat ttgctacaag tgtaccaaca gagagttgat
    16321 ttccttcctg tgcattcact ggttcaagta tttcttgtat ataaccagtg ttccttttat
    16381 tgattttttc aggcatctcc aacgttctcc aatggtctgg gatcgcgact tgatgaagca
    16441 gttcggtcgt ccgatcgatt gcttgtatgt ttttttctac gatagccatt gatttatgtc
    16501 catagctttt cagggcttct tcttttagca gcggaagcac ctcatcaaaa ggaatgatgt
    16561 cagctaattt aaaaaaagcc gtttccattg ccgtattgat ccggcgtccc aaaccgactt
    16621 cttgggccaa tctcatggca ttgatcgtat agaatctaat gttattttca gccaagtaac
    16681 gttttaattt taagggcaga tgcgtttcta attgttcgtc gctccaaaga gtattcaata
    16741 aaaaaatgcc acctggcttc aatcctttga ccaagtcata gctatgcagg taagctggtg
    16801 tgtgacaggc aacaaggtcc gcatgctcga caagatacgc tgaacgtatc ggcgtatctc
    16861 caaaacgaag atgagagaca gtcagaccgc cagatttttt cgaatcataa taaaaatagc
    16921 cttgcgcata tttatcggtg tgatctccaa taatcttgat agctgattta tttgctccaa
    16981 ctgttccgtc agatccaaat ccccaaaact tggcctggaa tgtttgcggt tctgtcaaat
    17041 ccagactttc ctttggttcc aaagattgat aagtcacatc atccacgatc cctatggtaa
    17101 accgtttttt gcgtatgctt gggtcttttt tcaattcatc aaaaactgct gagatttggt
    17161 cgggagtcac atctttagac cccaatccgt agcgaccacc aataacagcc gggcgaagtt
    17221 cagaatcata taacgcactt tgaacgtcta ataagagagg ttctccacct gcccctggtt
    17281 ctttacttcg atcaagaaca gcaattgttt ttactgtatg aggcaacttt tgcacgaatg
    17341 tttccactgg aaaaggacga taaagatgga tattcaaaaa acctgttttc cgtccgtttg
    17401 cattcaagta atcaatcgtt tgttcaatcg tctgtgcaac tgatcccata gaaacaatga
    17461 cttcttccgc atcgtctgct ccgtaataag tcaccaagtc ataagaagtt cctcgtaatc
    17521 ggttgatctc tttcatatat ttttgaacga tttcaggtaa tttatcataa taggggttga
    17581 tcgtttcccg ttgttgaaaa tggatgtctg gattctggtt cgtaccacta acagtcggat
    17641 gattgggatt catccctcgt ttacgaaatg aagctaattt ctcctgattg atcagaggag
    17701 ctaattcttc atattccaaa acttcgattt tttgaatctc gtgactcgta cggaatccat
    17761 caaagaaatt caaaaaaggg acttctcctt caatagaagc aagatgggca acaggtgcta
    17821 aatccatcac ttcttgtaca ctgctttcag ctaacatagc aaatcctgtt tgtcttgcag
    17881 ccatcacgtc tccgtgatct ccgaaaatat tcaacgcatt tgtcgtcact gcccgactag
    17941 caacgtggaa aacacttggc agtagttccc cagcaatctt gtacatattc ggtatcatca
    18001 aaagcagccc ttgtgaagcg gtatatgtag ttgtcagtgc accagttttc aatgatccat
    18061 ggaccacacc agctgctcct gcttcggatt gcatttctac tacttttact ggttgaccga
    18121 atacgttttc ttttcctgct gctgaccatt gatctactaa ttcagccatg gtcgaactgg
    18181 gtgttattgg atatattgca gcaatctcgg taaatgcata agaaatatat gcggctgccg
    18241 tattgccatc cattgttttc atttttcgca tgattcatca tccttgttca tattctctct
    18301 tattatctgt tccattataa cgtaaaacat gccatttttt tcttttattt ataaaaatat
    18361 tttacatgta tctatttgaa ttggtcatct aatttttaga caaacagtct aaatcgttgc
    18421 ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca tggatatatc
    18481 agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt catcgaatgc
    18541 tcctaaaaaa atggtcgaat tcatcaactt agcttgtccg tattgccgac aatggtttga
    18601 agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc gagtgatcaa
    18661 attgttcgat aaagaaaaag aaagcttaca gcgagggaac gtgatgcacc ggtatctcac
    18721 aatcagcgat ggccaaaaag cgatcaaaga gatcaaacaa atattcgata ctcaagacga
    18781 gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac taaagctgac
    18841 agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc aagcacatat
    18901 tcgatttgtt ccaactgtca tcttgggtaa agaaatcttt gatgaatcta tttcaataga
    18961 ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtg
//
LOCUS       DARBDN010000048        18817 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000048 DARBDN010000000
VERSION     DARBDN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.048"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            111..1538
                     /locus_tag="SCH06_001659"
     CDS             111..1538
                     /locus_tag="SCH06_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1078224.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1630..1995)
                     /locus_tag="SCH06_001660"
     CDS             complement(1630..1995)
                     /locus_tag="SCH06_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEG1078225.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPLDVQNK"
     gene            complement(1992..2357)
                     /locus_tag="SCH06_001661"
     CDS             complement(1992..2357)
                     /locus_tag="SCH06_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEG1078226.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2549..2797)
                     /locus_tag="SCH06_001662"
     CDS             complement(2549..2797)
                     /locus_tag="SCH06_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078227.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2796..2924
                     /locus_tag="SCH06_001663"
     CDS             2796..2924
                     /locus_tag="SCH06_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HEG1078228.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2981..4675
                     /locus_tag="SCH06_001664"
     CDS             2981..4675
                     /locus_tag="SCH06_001664"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEG1078229.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4679..4798
                     /locus_tag="SCH06_001665"
                     /pseudo
     CDS             4679..4798
                     /locus_tag="SCH06_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4775..4948
                     /locus_tag="SCH06_001666"
     CDS             4775..4948
                     /locus_tag="SCH06_001666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078230.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5326..6459
                     /locus_tag="SCH06_001667"
     CDS             5326..6459
                     /locus_tag="SCH06_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEG1078231.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6490..6810
                     /locus_tag="SCH06_001668"
     CDS             6490..6810
                     /locus_tag="SCH06_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HEG1078232.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6839..7303)
                     /locus_tag="SCH06_001669"
     CDS             complement(6839..7303)
                     /locus_tag="SCH06_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078233.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7435..8688)
                     /locus_tag="SCH06_001670"
     CDS             complement(7435..8688)
                     /locus_tag="SCH06_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078234.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8717..9034)
                     /locus_tag="SCH06_001671"
     CDS             complement(8717..9034)
                     /locus_tag="SCH06_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEG1078235.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIINLYRR
                     LNA"
     gene            complement(9060..9380)
                     /locus_tag="SCH06_001672"
     CDS             complement(9060..9380)
                     /locus_tag="SCH06_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078236.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9844..11259)
                     /locus_tag="SCH06_001673"
     CDS             complement(9844..11259)
                     /locus_tag="SCH06_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1078237.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11276..12592)
                     /locus_tag="SCH06_001674"
     CDS             complement(11276..12592)
                     /locus_tag="SCH06_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078238.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12742..13440)
                     /locus_tag="SCH06_001675"
     CDS             complement(12742..13440)
                     /locus_tag="SCH06_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEG1078239.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13729..14685)
                     /locus_tag="SCH06_001676"
     CDS             complement(13729..14685)
                     /locus_tag="SCH06_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEG1078240.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14798..15631)
                     /gene="msrA"
                     /locus_tag="SCH06_001677"
     CDS             complement(14798..15631)
                     /gene="msrA"
                     /locus_tag="SCH06_001677"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEG1078241.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15806..17440)
                     /locus_tag="SCH06_001678"
     CDS             complement(15806..17440)
                     /locus_tag="SCH06_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078242.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(17427..18812)
                     /locus_tag="SCH06_001679"
     CDS             complement(17427..18812)
                     /locus_tag="SCH06_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078243.1"
                     /translation="MCTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAI
                     AEAIALTIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIV
                     RLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEA
                     LSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTN
                     LFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFL
                     LVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKH
                     EVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKH
                     GLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVT
                     KKEINKKNENK"
BASE COUNT         5951 a         3707 c         3144 g         6015 t
ORIGIN      
        1 ttttaacggc atttatatgc tttttcagaa attaactgat gatttcaaaa agaaaacatg
       61 tcataatatt tcccatattg tgcaaaaaaa tacaaggcgg aggctctact atgattgaag
      121 aatatattga gaaaaatatt ttaagacagc tgtttttatg tgggcaattc tatgtaaata
      181 aagaagtcaa tctagaaaag ctctccaatc tcctgcatgt ttgcaaaacc actttactca
      241 atgatatcaa taacataaaa aaagaatttg aagaacagat cgcttataca catcgggaaa
      301 aggaccgtta cactttatat ttttcagaac atatacctcg atgcaagatc atgcagcaat
      361 tgtctcaaaa ttcgttgttt ttaaaaactt gtctgcttta tttggaagaa gatgaacctg
      421 attatcttca attaactgaa tgtgaattca tctctgtcag caaagcttat tcattaaaaa
      481 aacaagtatt agcttacttt aatgactgcg ggatcgaaat cgaccgctac tcccctcgat
      541 tcactgaaat ggaaagacgt ctgctgcttc ttaatgtgtc gtatcgttta ggcggtttta
      601 attcttggga gctacctgaa tcgttttttg aacgtgccga tcgtttcatt gaatccgtaa
      661 cggaaaatag tggcagattt tatgataaag aaaataaaga aatcttatcg attggttttg
      721 ctatcagttt cctacgccag caagtgtgtg ctgtgacaat agattcaaaa tttatcgaag
      781 aaatcaaaaa acgtcctatt tacaattatg tcgaatcagc atgggaaaac actgatttcc
      841 aaacctatta taaaaaagaa gaattcgcct ttattttgac actattcaat ctttgtaatt
      901 atggtttcca ttcttatcag ttgattgcgg aagactttca acagctacac caagtgttta
      961 ttgacaatac tcccgaaata aaagaactag ttgctacctt tgaatctcac ttcaatcaag
     1021 aattattcgg aaaccaaccg ttcgaacgtg cgctgattca tctgatgcgt tcggcttggg
     1081 ataactatca attattcatg ccagaaaaat tttatctttt aaatgaggaa cagacaaatt
     1141 tatataaaga agtccagaca attttttcca gctggtccag ccagttacct tatgatctac
     1201 ggttgaatcc taattgcatg cgggcttttg tgatcgaatt gagcggaatt ctccgtctga
     1261 caaaagaaca tctgactatc tatatcgtca caaattcgga tgttcattat ctgatttatc
     1321 gggaagcctt ggaagctgta actactttcg attttcaagt tgcaccaaca atttattcaa
     1381 gtatatctga tataaagaag tatgcgcagc agtcctcaaa ccgggtatta tgtgaacgta
     1441 cattatatac accagatgcg gtccaatatg aaaatattat tcctatttcg atcaatacga
     1501 tcgatcgagc tatcatttca gctgtgcaaa acaaataagg ggctgtgaca aaaatcatgt
     1561 cacagcctct tatttgttga agatgcccat ttctgtaaca atctcttgat acacgtcagg
     1621 ctcacaacct cacttatttt ggacatctag gggtccgatc tctttattta aaaaataaga
     1681 aatgatggtt cggataacta ccaacgccgc tagttggaaa atatcctgca aggtaggttt
     1741 gataatcgat tcgatgatcc cagctgaaac aagaatttcc aaacttagaa gtatatagcc
     1801 tcccaacatc tttttaatag cattgttctc gcttactcgg tcgctttgca cttttgtatg
     1861 gacaaataaa tatttcaaaa aatccttgat tgatagacaa acaccccaaa ccaataaaca
     1921 gatagcaaag atatcaagtc ccagtacaag tttttcgaaa tatggaagaa gaaactgcat
     1981 caactctgtc gtcatcctac ctctcctctt ctttgttttt ctttgtcttc tatttcctga
     2041 ttcaagaaat aagaaatgac tgttcgaatg ataataataa gtgcaagctt caaaatatct
     2101 gtccaagtcg gcttgataac tgactcgatg atatcagcaa cgactagtac ttccaagctt
     2161 aacaaaatat aacttgctag cagttttctt gtatctgcat tacgagtatt acgttctgca
     2221 tagtttttct tgacatgaga ccaatcaaaa agtttgaata gaacaagaac gatcccgaca
     2281 attaagatac cgatagaaca aatatttaaa atagcaatga tccattctag aaattcaatt
     2341 aaatttgagc gaaacatata cgctacctac tttcttttaa tttgttccta ttcttttatt
     2401 gtaaaagaaa gttaccttgt tcgtctattt aaaagttgtt ctaatgataa cggttcgctt
     2461 aaatttttct ttttcactct cccatttttc tccctccatc cataaatcgt ggaagtatcc
     2521 aaaacaacgt agcaagttaa aataaggctt agtccgtcat cagcttttca aagaagcact
     2581 gtctcggtgc tttttttgta cccaaatttc taaaaataga accatacacc tcctcaaatc
     2641 ttttcttctt acctacccta tttttattta caggaaaatc agacacttct tcttttttgt
     2701 caaaatttcc tttttcttct cgtcctatca tttggcattc taataaaaac gaactatcct
     2761 tggatataga aagagaaaac aaggaggcgt ttttcatgag taaaaaatta atcaaagtcg
     2821 gcatcggttt aggtttgctt gcccttggcg ctgcatatct aggaaaaaag acaggactat
     2881 tcgaagatga cagtcattta tatgatgaat tcgaatcaat ctagcatcct atttagttga
     2941 atcactacgg acatacttgg aagacattgg aggaatcaca atgagaaaaa gtaaagcaat
     3001 aatgattggt gccggtattg ccaatatggc agcggctgtt tatttgattc aagaaggcaa
     3061 atggaaaggg gatcagatca ccttttattc attggatgat cacggttcaa atgatggtgc
     3121 accgaccgac actgtagtgg atgaatattg gaataaaaac catccattag aaaaccaaaa
     3181 aggctatatt gctcgaggcg gtcgcatgct taattaccgt acctatgtag atttgatgga
     3241 tctgttaagt cgaatacctt ctgttactga gccagggatg actgctgaag aagatacgag
     3301 agattttgat gcaaaacacc gaacctttga caaagcacgt ttgatggaag gtggcaaagg
     3361 aatcattgat ggcggaaaac tgggattcaa taataaagac cgtattcttc tgactaaact
     3421 gattgctatg cctgattcag aagaagaaaa actagacaat atcactatcg aagaatattt
     3481 caaagatgat ccacactttt ttgaaacaaa cttctggttt atgtgggaaa caacatttgc
     3541 tttcagaaca cgtagttctg ctcaagaatt gcgtcgctat atgcatcaaa tgatttatga
     3601 attcactcaa atcgaacatc tagtgggcgt caatcgaaca cgttacaatc aatacgaaag
     3661 tattatgctt cctttgatcg agtacttgaa agaacaagga tgcaaaatca ttttgaaccg
     3721 ccgtgtcact gactgggaat tcaaagaaac accgatgcaa gatgaaatca ctgtgactgg
     3781 tttgaaaatt accaatacac tgactcaaga agaagaatac gttgtggtcg atgaagatac
     3841 agcagttatt ttcactaatg ggtccattac agattcagct actttaggag attacgaaac
     3901 accagctgta gaaaatatgg attatggtgc agcttctagt ctctggaaaa aagccagtga
     3961 acgtttctac aacttgggaa atcctgacaa attctttgct gatcgagatg caagcgaatg
     4021 ggtcagcttt accctgacga cgaaaaacca tttgttgttg aatgaaatca cccgtatcac
     4081 gactcaagaa ccaggaaatg ccttgaattc atttatttca accacaccga tcacgccgtt
     4141 aggccaaaaa gatgtcaata tgtctattgt cgtgcatcat caaccgcatt ttacgtctca
     4201 gaaaccaaat gaaacagtta tttggggtta tttcctttat ccaagacgac gtggcgaatt
     4261 tgtggataaa cagtatatta aaatgaatgg aaaagaaatg ctagaagaac tgattggaca
     4321 actttcaaaa gtagatcctg gaccagtgaa tattcgtgaa aaagaaacag aaattttcga
     4381 cagcgtaata aataatatcc ctgtctatat gccttatgct tccgcgttgt tcaataatcg
     4441 tgccaaaagc gatcgaccaa aagtcattcc taaacattcg accaatctgg cctttacagg
     4501 agaatttgtc gagcagcctt atcagatgat ctttactgaa caaagtgctg tacgttctgg
     4561 agaaatcgct gctttccatt ttgcgggtat tcctatgtcc cgtcttgtca aaacaccgcg
     4621 ttacgacaaa gatattccta ctctagctcg tgccgcaaaa aaaatgtttg aataatcaag
     4681 aggttgtgaa aaagctgccc tgcatcaagt aataagaaca accaggctaa aacagcttct
     4741 tatgtttttg atttggttgg acttattacc gcagatgcaa gcttttgaac accgtttacc
     4801 aagaggttat gaaaaagctg ccctgcatca agtaataaga gcagccaagc taaaacagct
     4861 tcttatgttt ttgacttggt tagacttatt accgcagatg caagcttttg aacaccgttt
     4921 accaagaggt tatgaaaaag gcgtttagtt tcgagtatga agaaaaattt tgtgaaaatg
     4981 gttcctcacg tttttgcata aatttgactt aataccgaga aactgatccc ttctgtcata
     5041 acctcttttt atttatgtct gtttcttttt gaaaacaact attttttcaa cgtttactct
     5101 cttgccaatc caacatcatc taacggatac aactatttca atgattacca ttacactaaa
     5161 aaatcggaaa cacacctctc cgaacacaaa tacataagac tatagaatgt ttcatttaag
     5221 aaaaaaagcg tttcattatc aaaaaggtaa gatctccttt aaaatgaaat tatctgtagt
     5281 actaataatg cagacaattt tatgaatctg aaaggagcat ctccaatgaa agcagtcact
     5341 tggcaaggaa aacagaaaat ggaaatcaga aacgtagatg atccaaaaat attagaacca
     5401 acagatgcaa tcatccgtat cacagcaaca gccatttgcg gctccgatct gcatctttac
     5461 catcatggtg aagcagtttt ggaaaaaggg tatgttgtag gacacgaacc aatgggaatc
     5521 gttgaagaag tgggatctca agttcaaaca ttgaaaaaag ggcaacgtgt ggttatccct
     5581 tttaatatta gttgtggtca ttgtcatttc tgcctgaatc acatggaaag ccaatgtgat
     5641 gaatcaaatc cagatcagtt atatggcggg cttttcggat ttggcaagtt gaacggtaat
     5701 cattggggtg gtcaagcgga atatctaaga gttccttatg cagactctac ttcatttgtt
     5761 gtaccagata atgatcttcc tgatgaaaaa gttttatttc tatcagatat tttgcccaca
     5821 gcttattgga gcgttgaaaa cgcaggagta aaaaaaggcg atacagttgt gattctaggt
     5881 tctggtccag tcggtctatt cgctcaaaaa ttcgctgtta tggctggagc agagcgcgta
     5941 atcgcagtag atccagtaca gcaccgtcta gataaagcgg ctaattacaa tggggttgaa
     6001 acttatttct tagaagacac ggcacaagct ggaacagaat tgtatgaact ggctaaaggt
     6061 ggcgcagatg tcattatcga ttgtgtagga atggacggat tagagcctgt caaagaaaaa
     6121 gcgaaaaatt tagtaagctt acaaagcggc acaatctctc cattacagat ggcatcgcaa
     6181 gctgtcaaaa aatttggaac agtccaagta actggtgttt atatgactcc agcttcttct
     6241 tacccgctgc aagaattttt tatgcgggat atcgctgtca agcatggaca ggcaccaatt
     6301 atccatctaa tgccaaaaat ttacgcaatg attgcagaag gactattcga tcctacacaa
     6361 atcattactc attcgctgcc actatcagaa gcagcacaag catatgagat ctttgacaaa
     6421 aaagaagata aaaatataaa agttgttttg aaaccttgaa ttcagtaaaa aatacaggtg
     6481 attttcttta tgcccaaaat caaacgaaat acccatgaga tcgaaatagg aaaagaagaa
     6541 gatatcgaaa tacgaggacg tcgcttccgc ttctatttcc aaaatcgtta cacattgatc
     6601 tcactggctg tcgatttatt aaccgggatt ttctatattt ttggaagcct tgcttcctta
     6661 actaaaatcc ccgatcgata tggcacctat ttttatttgg ctggtgctat tttcttgacg
     6721 attcgtccta ttctcagaat cgtaaggaac atttttattt acgacgaaaa aaaagcaatg
     6781 aagagaacaa gcaaaaaaaa agaggcatga gaatttttca aatctcatgc ctcttttttc
     6841 accctatcgt atcactttga tacagacgag cggtcgtccc actttcttcc ttgaccattg
     6901 tcaaaaatgt ccactcgtat cgttcataaa acgtggtatg atctgtaatt aagtaaagtt
     6961 tttcgtaccc aagttgatgc atttcttttc tgatttccgc taatatccgc ttggctatcc
     7021 cctgcttacg cttttccggt tcaacaaaca gggcacaaag atttggtgtc agatcagggc
     7081 ggttatggaa gtcgttttca atgacgcccg ctcctccgac gatggtttct ttttcatcta
     7141 agaccacata ccattgagga atactttcct tattagcgat tccagtacga atactttcct
     7201 catacacaac agcaggaact ccccattttg atgaaaacca attcgcgctt tgttttacta
     7261 attctgggtg ttctcttaat ttgatccagt tatatgtaac caatgtttaa acctccgact
     7321 aaaataaaac gtttacaaaa attatacaag tctttatgaa aattagcaat gacaacaata
     7381 gtgatgtaaa aaaaaaaacg gaaaacaatc acttgttctc cgttttttga ttaatcaagc
     7441 atctaaagct tcttttcttc tttcttggat cgtagctacc ttgacgaacg gtagatagat
     7501 caaaatagaa agaaccaaat tgacagcggc tagtacacca cctgcaatac tttttgttgc
     7561 caatacaccg ccaataattg gtggagttac ccatggaggc ataacggtag ctgctggcac
     7621 taaacctgta gaagtcgcaa agtaagcaac actaactaag accattggtg tcaaaataaa
     7681 tggaatgaac atgatcgggt tcaacacgat aggtaaccca aacatcgttg gttcattaat
     7741 attgaagaca cctggcgcaa tcgacaagtt tgttacaacc atatatggtt tgtttttacg
     7801 tcctactaaa taaatagcta acagtaaacc taaagttgca cctgttcctc ctaagttgac
     7861 aaagctgtca aagaaaggtt tgttcacgat aaacggtgcg ctatgtccag ctgcgattgc
     7921 attaacgttt gcttcaatgg ctggcgcatt gattgtttgc atcaaaggat cgaccatatt
     7981 cgctccgtgt aaaccaaaga accataagaa tggtgtgata aatgcaagca gtaaggcaga
     8041 tggataagag tttgcaagtc ccataaatgg ttcttggacc actgtataga aagaacctac
     8101 gatatcatca acaccgaatg cagcaaaaat tgcagcaact aaagcaaacg cagagatagt
     8161 gatcattgct ggtagtaatg aagcaaatgc ttttgcaact gccggtggca caccatcagg
     8221 cattttgatg atcaattttt catttccgct taaacgtaca aagatttctg ttgaaataat
     8281 cccaacaata atagcaataa acaaaccgtt tgagctcata cctaatgctc cgcctaaagc
     8341 gaagaaagag cctaaagaaa tcacacctgc ggaaacaccg tcttttcggt agccgttagc
     8401 taaatgataa gcaagcaaga aagcaatcaa gacagaaaga atggcaaatg taccgttcca
     8461 agcagcagcc ccgaatcctt tccatgattc accaccaaaa attgagttca tcaattcttg
     8521 gaacccggga atcggtaagt tattgatcat tactgctaat gctcctaaga tcattaacgg
     8581 catactcacc ataaatgagt cccgaatcgc aactaaatgc cgttgtgcac caatttttga
     8641 tgctacaggt ataaaatgtt tctccataaa tgcaacaaat ttatccataa atcttccctc
     8701 ttttctttac tgtagattac gcgttcaatc gacgatacag attaatgatc tcttttgcta
     8761 aatctgtaaa agctatagat gtcatcagat gatcttgact gtggaccgtc aaaagcgtga
     8821 cttcaacgtg atttccttgt gcttcttgtg tcagcatctc tgtttgagag tgatgtgctt
     8881 ggactaaaga ttcctctgca tctttgattt tttcatctgc taaagtgaaa tcaccttttt
     8941 tcgcagcagc aatcgcttcc attgcatcgc tttttgcatt tccgccaaac atgatcagac
     9001 ccatgatggc ttctagattt ttttgatctt ccatttattg tatcctccga taatttttat
     9061 tatttgttta ttagtttttc tgcttggtcg agtacttttt caccattcat catgccatag
     9121 tcagccatat tgattacatc taaaggaatg cctttaggtg ctagcttttc agcaaattga
     9181 ttttgcataa agcgtacttg cggtcctaaa agtaaaacgt ctacattttt agattctagt
     9241 tgattatccg catctgaagc agatacagca aagatgtctg cttccattcc ttttgcttct
     9301 gctgcctttt gcatttttgt gactaggaga cttgtactca ttccagctga acatacaagc
     9361 atgattgttt tcttttccat tttaaacacg ttcctttcta tacttacact tgtatataag
     9421 caagtagcgt gccaacttta aaagcgcttt aaaaagttga tatcatcaca tttaaggtct
     9481 ataccaagtt gcatacacac taaaaaagaa agcgcacact aaacacacaa attaattttt
     9541 attacctttt ttcttttaac gtgcacaaaa aaagttgtga cacaaaactt gtcacaactt
     9601 ttttcaaata aacggtattc aaaagcttgc atctgcggta ataagtccaa ccaagttaaa
     9661 aacataagat gttgttttta ctttgctatt cttattactt gatgcaggac agctttttca
     9721 caacctctca ataaacggtg ttcaatcagc tgaccctggg tattagctca aaacgctgga
     9781 ttcacaacct cttttatttc aaataaccag taaatacaat gaacatctac aaaaaacttc
     9841 tatttattta tagatttcgt caggcaaatc caattctctc ttatcaatca aagtctgata
     9901 ccacgaagca gattttttca atgttctgct tcgttcatcg ttcaattcga ttcgaactaa
     9961 tccatatcga ttcttaaatg cattcattgg tgacacacag tcagtgaatg cccataacat
    10021 atagccttcg caatttgcgc cttcttctgt tgctttgatc aagtaatgca aatgctgtcc
    10081 gataaattcg atacggtaat catcttgcac gattcctttc tcatccatat actgttcttc
    10141 atattctctt cccataccgt tttctgttat cagccaaggg atattatgat aattttcttt
    10201 tagatacatg gctatatcat acatgatttt cggatagatt tcccatcccc tggaattatt
    10261 cattttcttc ccaggtaaat caaagacttc ataatatcgt tcaggatgga aaggtgtctc
    10321 ttcattccat tgataacgag gggcgcgaac gcgtttagga taatattgat tgattccaag
    10381 gaaatctact gtatgatgct gaatcgtttc taaatcctct gttgcaggat cgaaataaat
    10441 cgattgtttt tgacacaact ccaggaactc ttctgtgtag tatcctttta ccatcggatc
    10501 aaaaaatact cgattataaa acaaatcata catataagca gctttttggt cttctggaga
    10561 attggatcga gcatagacca tttcaggatt taaaatacag ccaatccttc caccataatt
    10621 tccgctgcgg taaatctcta ctgctttagc cgttgctaaa actttatgat aattccacat
    10681 catccacttt tttgtgtttt gttcatgcgg ccagcgaaca gcatccaaat agcaacgcgt
    10741 ttggggaacg attggttcgt tgaatgtaaa ccagtttttt accctatcac cgtaacgatc
    10801 aaaggcaatt tgagcatact tagcataaaa atcaactact tttcttgaag accagccatc
    10861 atatttttcc aaaagaaaag ctgggacttc ataatgttcc aaacaaatca tcggttctac
    10921 gtctgcttcg atcaaagagt cgatcatttc acttatatgc tgagcatatt cttcatctac
    10981 tatacagttc tcataatcag taaaaaaacg agcccaattg atagaagtcc gataatgtgt
    11041 cagatggatg gatttcatca gatccacatc ctgctggtat tgttccataa aattagttgc
    11101 tacggctggg ccatacccat tatgccaaac aaaatgttca tttttatacc agctatctat
    11161 aaacgaatcc tgtccttctt tttttccttt ccaaccttcc gtttgccaag cagaagatgc
    11221 agcaccaaga ataaaatttt ttggaatagt aattttcatg atttcctcct gttttttaga
    11281 tcccatcatt ttccacacga tttgctactt ttacaaatgg cagatagatc aaaatagaaa
    11341 caataataca aacaagttgc gtaataactg caccgatatt tcctgctgtt gccagataag
    11401 cattgacgat cggcggcatt ggccaaggga ccattacaac tgctttcgcc gcaaatccta
    11461 aagcggttgc aaaataacca atcgttccag tgataagagg cgttaagata aacggaatag
    11521 ctaaaattgg attcagcatg atcggcatac caaaaataac tggttcattg atgttgaaga
    11581 tcccaggagc aagggataac ttggtgattt gtttcatatc ttcccgtttt ccaactaaca
    11641 atactgcaat cagtaaaccg atcgtgactc cagacccgcc catactcata tacatatccc
    11701 aaaatggcat agtaataatg ttcggtactt cttttccagc ttcaaaagct tccgtattta
    11761 cagcaattgc cgctaaaagc aacggttccc gtatcggctt caccatttga tttccatgga
    11821 taccaatcac ccaaaagact tgcgcaataa acatcaatag caaaataccc ggtaaccctt
    11881 gtacgacacc ttctaatggg cgttgtacga cattgtaaat gatatcataa aggtacattc
    11941 ctgtaagttc tttgatgata aatcccgcag ccgcgatacc cgatacagtc agaatcgtcg
    12001 ggaataaagc agaaaaacta gcagaaacat tcgttggcac ggtatcaggc attctcagct
    12061 gtagtttctt ctgtttcctc aaccagcaat aaagttcaat agaaaggatg gagaccaaca
    12121 ttcccaaaaa taaccctttc gtatctgtat attgtttagc caatacgttt tctactataa
    12181 cagtctgatt ttcattcact aattcataaa cagttggatt aacagataaa taagacatca
    12241 ctgcgatgat accagggaat acaccatcca ctttattcag cttggctaat tcgatcccta
    12301 tcagaaaaac agcatagatg gtcaagaaac ttagtgtgac atagctgatg gcagatgcga
    12361 taggctttaa ttcttctaaa aaacgcaaga aacttatctg tgctaagcca ttttccgagt
    12421 caaagaccat tgctgaaaac aatgtgccaa aagcacccgt aataattacc ggaatcaatg
    12481 cagcaaatgc gttttttatc accatgatat accttaaatt attgattctc gttgccacgt
    12541 tccctaaaac attggctaat ttatccataa aactcattcc agatcccctc attcctgctt
    12601 cttctccttg acgtcatctc tttttgtcta ttagtcagcg cttacatttc gatgaacaga
    12661 aactatttac tcctcttttt taccaaatat aaaacaaaaa ttcatctgat gtatttatca
    12721 taaaatacat cagatgaact gtcaattagt ttctttttct cctattattt tctgtaattc
    12781 tctccgattt attgccatat ggacagtcat tgcatcaaac gcagcaagtg cattccgcct
    12841 ttcgatggcc tgaacgatct ctgtatgaat atcgatcgtc tcgattttca gatgctggat
    12901 atcataattt ttattaaaca aagcaattga ttcattaatg attgggataa tatgcagcaa
    12961 ggctacgttt ccgctagctt ctgcaatcat cgtatgaaaa tcgatgtcta attgaacatg
    13021 ttcttgtgtg ccttctcgaa aagaagtttc aatcttttgc gttaattttt tcatttggac
    13081 gatttgattc ttcgttgcat attccgctgc caaacctgcc atcttaggct ccaataaata
    13141 tctcagttca aataagtctc gtatcatccg atcctgatct tcaatcaaag aaaaaccgag
    13201 tgggtcattg gcaatccctc gcttatcact gacaaatgtc cccgctcctt gccgaacttc
    13261 aaggatattc ctggaagcta gagcccgcac agcttctcgc accgtgcttc gccccacctc
    13321 taaataatcg gacaattcat attcattcgg cagtttatct cctacttgca actgcatttc
    13381 ctttaaatat ctaaggatct tgtcagtagt tacttctact agggttttat tttcttccaa
    13441 accacatacc tccttttcat ctgatgtatt ttttcgtaat tattataaca cgtttgaatc
    13501 atctgatgat tttttgtata caaaattgat taatccgttc atagacatac aaacgaagaa
    13561 gatatttacc ataaaaaaga ctaggataaa attcactcct agccttcgat catttttatt
    13621 ttgaacgaca aaaaatatga tgttcaataa cagacgatct tcattcgatt cttgatgtca
    13681 tcttttgttt tttttaatat atggataaaa agtttgatta catcgtttct attctagaat
    13741 ttggtcgatt ctcaattctt cttctggtga gaaatctaaa ttatccatca ttcgaacact
    13801 ttcttgtaac tgacttaacc gacttgctcc gaccagtaca cttgtaacag atttttgtcg
    13861 caaattccat gcaagggcca tttgcgctaa tgattgtcct cgtgatacgg cgattgtttg
    13921 cagtgctttg attttttcca gagttgatcc aacttgttct tctgaaagga atggtatttc
    13981 cttacgatgt gctctagaat cttcaggaat accatgtaga taacgatttg tcagcaaccc
    14041 ttgagcaagc ggactgaacg tgattgcccc tagcccttct tcttctaata ctggagatag
    14101 atcgtcttct agtagtgcac gagaaaacat attgtagcgc atctgatgaa taatgaacgg
    14161 tgcttccttt ctttttaaaa tttcagtcat tttttttgta tcttctccat tatagttgga
    14221 tataccaata tataatgctt ttccttgtct tacaagttgc atcaaagctt ctgctgtttc
    14281 ttccaaaggt gtatcagggt ctgggcgatg atgatagaag atgtcaacat aatctagccc
    14341 cattctttgg agactttggt cacaacttga aatgatggat ttacgagagc cccattcccc
    14401 atatggccct tcccacatat gataacctgc tttgctagaa ataatcagtt catcacggta
    14461 ggcttgaaaa tcttctctaa aaatacgccc aaagtttttc tctgcagctc cagcagggcc
    14521 tccataatta ttcgcaaggt cgaaatgggt aattcccatg tcgaatgcgc ctcttaaaat
    14581 ctctctttga ttatggatag gatcataatc accaaaattt tgccataatc cgagagataa
    14641 aatcggtaat ttcaaacctg aatgaccgga tttacgatat tccatttttt cataacgtgc
    14701 actatctgca atatacaatt tttctcctcc tcatcaaatc tttttaaaac gctttctttt
    14761 ttctattttt agtttactac attttaaaga aaaggagtta atcaaaatga ttttttcgta
    14821 tatttttttg ccatttgttt tttactcgtt gatagatcag aaattgatta cgtgcttgct
    14881 ggattttttt ataacgtttc ggttgttttt tgtaaaattg ctgatgatag ttttctgctg
    14941 gccaaaacgt accggctggt tcgatttttg tgacgattgg ttggtggaaa gttcctgaac
    15001 tgtctagttt ctgttttgat tgttccgcta attctttttg tcgttcgact tgataaaaaa
    15061 tcactggacg atattgcttc cctctatctt gaaattgtcc aaatgtatct gtgggatcag
    15121 taatttgcca atagattgtc agcaactcgc tataacttat ttctcttgtg tcataaatga
    15181 tctccacagc ttccacatga cctgtgtaac caccacttac ttgatcataa tttggttttt
    15241 caacatgtcc gcccgtgtat cctgacaaaa cagataggat cccttttttc gattcaaacg
    15301 gctcgaccat acaccagaaa catccccctg caaatactgc acgttcttga tagtcagcat
    15361 cttgcatggc atgcttggaa aagtcatatt tttgctcctt atcaaatcct tccgtaatca
    15421 ataaataaaa gtccattaca tcaggcgtca gattcattcg gatagctaat ggacgtagtg
    15481 ttgcttctag ttttgataac tgttctttaa cggatatatt ttctcttatg tcattctttg
    15541 tctgaatcaa tacttttcgt tcccaatctc gtgtattcgg attcaaaatc agattataaa
    15601 gtgtttgaat gaatatttgt tcctcatcca tagattctcc tcctttccga agaagacaag
    15661 ctagtgactt tagctgtaat ttatcataaa gtgaggaaat aagcgattac ttcatccccc
    15721 tacagatttt tcgtataaaa aagagagaat ccttatcgac agattctcct ttttaatcaa
    15781 tttattttat aaatgaaaag ttaatttacc ttttatggaa aactatttta aaaaataaac
    15841 ataaatatgc agttaatgta acaagataag aaataatagt cgttactgta taacttgtgc
    15901 ttactttaat atcagcaact cctttgactc cgcttatttg taccaatcca ttagcattca
    15961 cctgctcctt tacaggttga tgatttattt ctacattcgt tcctaaataa gcatatacag
    16021 gaagtgtgat tacttggctc ttctcattag ttactctata tatgatagaa ctaccagttg
    16081 ttttataagg aaggtttacc cattgactgc caatctttgc ttcgtgtttt attatatgct
    16141 ccttattctc caatgaagcg ataggagaat aatcatataa aaaataatcc attcctttag
    16201 tggtatacgc ctctactgtt tctttgttta caacaatatg tcccggctga gaaattattt
    16261 tttgattgaa atttttttta ctagaaacag ttaaagtgat taataacaaa acagtcataa
    16321 ataaataaaa tagttctctt gtcttattgt atcttctatt tttgaaaaat atcatcgtta
    16381 atatcagaga agagaatatt atttgcaagc ttaagatccg ccaaggaaat tgtaacaatt
    16441 tggctggcgt attttgcaga agataccatg gcaccaaact agttgtagct agccaagtca
    16501 aacacgtacc ataataaatc tttttttcta tgtttgttaa ttttttaaat aaaatcaggg
    16561 gaatacataa agataacaga ccaactagtc ccattgagta agtagttaag tcgttgttca
    16621 tagcttcagt cagactatcg aacacattag atgcatgagc atataaattt gtcacgctag
    16681 gtttgttgat tttttggtag agcatttgtt caaacatcgg ataccaaaaa gcactcgtca
    16741 gaaccaatgt cattcctgcc gcactaaata attttttaaa tatagcaata aaatctgcat
    16801 tcttgaaacc tttagaaacc aaacgaataa aaataaaaat gataattaat gctgtactca
    16861 ttaatgttga tagtacatgg ctgtacacta gcaaactcat actcaatgct agctttacag
    16921 acggatactt ttcttctttt ccagagatga tttgataagc ataaaataat acagggataa
    16981 caagtgttat tgcgatagct tcggcaattg cggaacgata gtagatgtct actgtccgat
    17041 aagcagagaa aatatagaga caactaaata aaaatgccgc ttttttttgt tttaaaaacc
    17101 gctcgccata atgataagct acgagtgttg tacacaagtt caataaccaa acgtaaataa
    17161 tatagcttac aatcaaattt tttgtcatcc aatataacat tacagctgga aaaaaagtca
    17221 gaaagggata aaaataattt acaccatatc cagtataatt gaatgtctca taattaatcg
    17281 gactggtaaa aatagtcgat aaccccttga ttcgagataa gtgaaaagaa agatctccag
    17341 tggtataaat actctgtgta tttttgaaaa agatgaaaga atatatacta ctaactataa
    17401 ttaatccact caatattact acttttttat ttattttcat tcttcttgtt tatctccttt
    17461 ttagtcacat atcgagaatc tttcaactta ttaggtgcaa atcgtttaaa acttgaatac
    17521 accactaaac aataagtcag aatactgatc cataaagcca tgagagcagt tggagtatat
    17581 tttgttgtaa tttctatctt attttctcca gcatttacat ccacattcac taagccatgt
    17641 tttttataag agtcatttac gactttaccg tttactttta cctgtgtacc taaataagca
    17701 tatactggta ctgtcacttt ttgctttttg ttgcttgcca ctgtgtaagt aatgttatta
    17761 tctgcagctt tatacttccc tttttcccac gattctccta cttttacttc atgtttttct
    17821 aagtgaggcc tttcttttat cgcttctgtt ggggcgtaat cgtataatcc tcccatatct
    17881 gatgttgtat aacgtgggag tgtttcttca ttgataacaa tatgaccgtg ttttgattgg
    17941 ataacttttg cgtaattttc ttttgctgct atagacgtga cgagtagaaa caccacagta
    18001 gcgccaatga ttaaccatga atatttttta ttcatagtct ttttcataaa aacaagcgtt
    18061 atgatcattg aagaaaaaaa gatttggata cctaagatac gccaaggaaa ctggagtaag
    18121 cttatcggtg ttttttgaaa caaaaaccat ggaaataaat tagttacgca tacccatgta
    18181 gaaactacgc caacatagat gattttttct tttttctcca tttctttcag tatgaataaa
    18241 ggaaaaatca acgcaaccaa tcctaataac cccatagtgt atgttgtaat atcgttattt
    18301 aacgcttgaa tgatactatc tgaaatagaa agtgcttcta gctgcaaatc tgttttgaag
    18361 ggactgtgta tttcttgata attcatctgc tgcaacatag gataccaaaa atagctagtt
    18421 aatgcacaag tcaaaaaaac agcctttact aaattcacga ccacaaattt tatatcgttt
    18481 tttatttgct tgcttaaaaa caaacgaact ataatcatac aagcaatcaa tgcactacac
    18541 aatagtgtag ttaagacatg agtatacaca agtagactta tactgacaga taaagcgatg
    18601 actttttttt ctctattgaa tatcaatcca taagcataat ataaaacagc tgggataatc
    18661 gtaagagcga ttgcttctgc aattgcggat cgataataga tatcaactgt tcgataagtt
    18721 gcaaaagtat ataaacaact aaataaaaaa gcagcatcta tctttttaaa aaacttttct
    18781 ccataataaa aactaatcag aatcgtacaa atattta
//
LOCUS       DARBDN010000049        18511 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000049 DARBDN010000000
VERSION     DARBDN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.049"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(28..852)
                     /locus_tag="SCH06_001680"
     CDS             complement(28..852)
                     /locus_tag="SCH06_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEG1078244.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(825..1505)
                     /locus_tag="SCH06_001681"
     CDS             complement(825..1505)
                     /locus_tag="SCH06_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEG1078245.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1528..2466)
                     /locus_tag="SCH06_001682"
     CDS             complement(1528..2466)
                     /locus_tag="SCH06_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEG1078246.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2711..3574)
                     /locus_tag="SCH06_001683"
     CDS             complement(2711..3574)
                     /locus_tag="SCH06_001683"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEG1078247.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(3716..6289)
                     /gene="mprF"
                     /locus_tag="SCH06_001684"
     CDS             complement(3716..6289)
                     /gene="mprF"
                     /locus_tag="SCH06_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEG1078248.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6430..7236
                     /gene="proC"
                     /locus_tag="SCH06_001685"
     CDS             6430..7236
                     /gene="proC"
                     /locus_tag="SCH06_001685"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEG1078249.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7315..8871)
                     /gene="rny"
                     /locus_tag="SCH06_001686"
     CDS             complement(7315..8871)
                     /gene="rny"
                     /locus_tag="SCH06_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEG1078250.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9282..10331)
                     /gene="recA"
                     /locus_tag="SCH06_001687"
     CDS             complement(9282..10331)
                     /gene="recA"
                     /locus_tag="SCH06_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEG1078251.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10440..11681)
                     /locus_tag="SCH06_001688"
     CDS             complement(10440..11681)
                     /locus_tag="SCH06_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEG1078252.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11921..12499)
                     /gene="pgsA"
                     /locus_tag="SCH06_001689"
     CDS             complement(11921..12499)
                     /gene="pgsA"
                     /locus_tag="SCH06_001689"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEG1078253.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12708..13631)
                     /locus_tag="SCH06_001690"
     CDS             complement(12708..13631)
                     /locus_tag="SCH06_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1078254.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(14370..15656)
                     /locus_tag="SCH06_001691"
     CDS             complement(14370..15656)
                     /locus_tag="SCH06_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEG1078255.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(15649..16917)
                     /locus_tag="SCH06_001692"
     CDS             complement(15649..16917)
                     /locus_tag="SCH06_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEG1078256.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            17169..17630
                     /gene="mscL"
                     /locus_tag="SCH06_001693"
     CDS             17169..17630
                     /gene="mscL"
                     /locus_tag="SCH06_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEG1078257.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(17690..18136)
                     /locus_tag="SCH06_001694"
     CDS             complement(17690..18136)
                     /locus_tag="SCH06_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078258.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(18229..18474)
                     /locus_tag="SCH06_001695"
     CDS             complement(18229..18474)
                     /locus_tag="SCH06_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEG1078259.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
BASE COUNT         5281 a         4048 c         3232 g         5950 t
ORIGIN      
        1 ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg caaccaatat
       61 tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga ttgttgctcc
      121 tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta gaaatcctac
      181 acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac cgattgctgc
      241 gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca tcacagcaat
      301 agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta gcccatccac
      361 gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata aaaagaacaa
      421 tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg taatggtcac
      481 gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc tcaaattcat
      541 caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga tttctgaata
      601 ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa cgactagcat
      661 ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg ctaaagagac
      721 atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca cacctagcat
      781 cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga attcatatga
      841 aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc cgcatactgt
      901 ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac atgcgcacta
      961 tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt tgttggttca
     1021 tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat tcgctgcttt
     1081 tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc tacagcttct
     1141 aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca gcggcctctt
     1201 ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc attgaaagat
     1261 gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt tttctcagca
     1321 atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac caaggttgac
     1381 ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac atgataagag
     1441 acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat ttcgatataa
     1501 cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag ctttcagatt
     1561 tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag tcaagctttc
     1621 taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct cagctacctt
     1681 cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca caaattcttt
     1741 tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg aaatcgctac
     1801 ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag tgacaaatgt
     1861 gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt caagcttttt
     1921 gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt tttcgcctaa
     1981 ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc aaacatgtgg
     2041 atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt ctgcttcttg
     2101 cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt tgctatccac
     2161 tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca cgaaaacatc
     2221 tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg gctccgttcc
     2281 agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg taaaatcata
     2341 catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt ccttgttcgt
     2401 atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca aaagatattt
     2461 tttcatttat atgctccttt caatgaacaa atcggaattt tacgatttat taacgtgaac
     2521 taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg atttaagcat
     2581 gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag ccatttcact
     2641 acaataaaaa actgaagaat accattttag gattcctcag tttttcatca cctattttac
     2701 ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa ccttttaacc
     2761 cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg gttggtccgc
     2821 ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg atttgatgga
     2881 tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt ttgatcatct
     2941 gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga tgttggatgg
     3001 cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt ggtttgacca
     3061 acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct ttgccaccga
     3121 caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc aaaccgattt
     3181 ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct cttagagcag
     3241 ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc ttcttaacaa
     3301 agatcttgac accggttttg atattgtatt tattttttag caataaagca gcttgataaa
     3361 cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg attttgtctt
     3421 ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc accatttcca
     3481 actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt atcttggctg
     3541 gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc gcaagtattc
     3601 tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt ttgtcatcgt
     3661 ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt gattcttata
     3721 attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt cctatcagac
     3781 tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca aaataacgtc
     3841 cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag gaatagaaaa
     3901 aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa aaatctgttt
     3961 ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc attttctcgt
     4021 atacaataaa cagattggct aacagatagt cagctaattc ctcagattct ttaggtaaga
     4081 cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg atgaagccaa
     4141 cgactttttg atctttacgg acaataccga caccgctaga taatacatat gatttatcaa
     4201 atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt gaaacttcat
     4261 ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg tatccttctt
     4321 tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct gttgctagat
     4381 caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga agcatcacta
     4441 cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct gcttgtttca
     4501 taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct cctaaaacaa
     4561 agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg tcttcttggt
     4621 aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg cctccgtatg
     4681 tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc gtagtatctt
     4741 cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa ccaataagcc
     4801 ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt attcgaccga
     4861 ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa aagccgaaca
     4921 agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga taaaattctt
     4981 ttctggataa ccacacagct aacagaatca agacatatac caatatcaac tgccaagata
     5041 acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta ggcagaaatg
     5101 cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag ccaaccaata
     5161 gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga aatagccgac
     5221 tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc gcaaaataga
     5281 cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga atgttatcta
     5341 aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc gtcataaaag
     5401 gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca tcttgccgaa
     5461 cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt ccacctggga
     5521 ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc gaaagcatcg
     5581 aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct cccgtccatt
     5641 gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg aagaacaatg
     5701 tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta ccgccgaaaa
     5761 gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca tcaataaatg
     5821 taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt gatacagtgg
     5881 ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga cttgctccta
     5941 ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca gcaagaagaa
     6001 actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc gtcacccaat
     6061 catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc aggatcgtca
     6121 tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca ttagcaatat
     6181 ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt tttaaaatca
     6241 gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca ttttcccatt
     6301 cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt aatttttcca
     6361 ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa tgctaaagga
     6421 gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc tattattgat
     6481 ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag tggacatttt
     6541 gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag taatcaggaa
     6601 gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat tgaaaaagta
     6661 ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc ttcaggaaaa
     6721 tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt acgtgtgatg
     6781 ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa tgaagctgcc
     6841 acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag cgtctatcct
     6901 ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc cgcattcgtt
     6961 tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc caaacagaca
     7021 gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct ttcaagtgat
     7081 aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac tgttgcaggt
     7141 gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat caatacgacg
     7201 atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt tttcgtgcct
     7261 tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt tttattattt
     7321 agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc caggataatc
     7381 cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt ctaaatccga
     7441 gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg cgtaacttga
     7501 ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac ggatgtagtt
     7561 ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg ctgcagctac
     7621 aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga tcgcgttgat
     7681 tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa cgtgagatcc
     7741 ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac gttttgctaa
     7801 ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa cctcgaccga
     7861 atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga tgatcttgat
     7921 tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc cgtattcgcg
     7981 aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac gcgctggatg
     8041 gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc ttcggattgg
     8101 atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat cgataccagt
     8161 cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac ctttcatttc
     8221 atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg ctgcgcagcg
     8281 ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt tggcacgctg
     8341 ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag tcgatttcat
     8401 gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt ctttttgttg
     8461 atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct gttttgaact
     8521 aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt catctttacg
     8581 attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt ctaacttact
     8641 ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct tagcttctaa
     8701 caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga ttccagcagc
     8761 tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca taaaccctaa
     8821 accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca taaaatccac
     8881 ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa ttattctaaa
     8941 ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact ttattctaat
     9001 gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta cttattcatt
     9061 aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt taaattgaga
     9121 aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta tgtacccact
     9181 cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg tcaaggagag
     9241 tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc tactaaaggc
     9301 aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat accataagct
     9361 gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat atagatttta
     9421 gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc accgctttta
     9481 tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga gatccctaaa
     9541 ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt ttttacgact
     9601 ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc tgcacgacgt
     9661 acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt gatttctgga
     9721 ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc gattgttttt
     9781 gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg tgcttgtaac
     9841 ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa agcagcaact
     9901 gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc gatctctaga
     9961 ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac acctaatttt
    10021 tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt tccgccattt
    10081 ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact ttcaggtcca
    10141 tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac atctaacgca
    10201 agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa tttcataata
    10261 gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc tgctttacga
    10321 tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat ttcattatcc
    10381 ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat tcgcatttat
    10441 cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc attatatctg
    10501 atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc tttagatgaa
    10561 atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc agccactccg
    10621 gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc catctgctcc
    10681 acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat ctccagaaaa
    10741 ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc agatacacca
    10801 gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc tgctgttaca
    10861 gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt atcatcgccg
    10921 tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc taaaagagct
    10981 tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac ttcatttggt
    11041 ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt tagctcagtg
    11101 accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag tttttcttca
    11161 gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg tttcaactca
    11221 ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa agtccctaaa
    11281 gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga ctgttgcaga
    11341 ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt tttgtatcct
    11401 tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt tgtcaggtca
    11461 tcttctgtcg gtcctaatcc gccacataag agtatgagtt cacttcttgt ttcagctaga
    11521 gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata ataaacttcg
    11581 atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac gacttgtcct
    11641 agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg ctcccttata
    11701 tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag ctgtgacaaa
    11761 aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa cctcggtcat
    11821 aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct tgtgactcag
    11881 agttagacgg caggctcaca acctctccac taaacgatac ttacattgat cctttgaaca
    11941 caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc agacaagcat
    12001 aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta ttgataaaca
    12061 gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa gctgcagcca
    12121 tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat tcacgacaga
    12181 caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg ataaaagcag
    12241 tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta gtgacaaggc
    12301 ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa gcaaaaataa
    12361 ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat tgtccccaat
    12421 ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta agtacagtta
    12481 atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt gactatcagc
    12541 gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga gtatttttat
    12601 tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt cacgatcctt
    12661 cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca ttctgcgtat
    12721 tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt aactggtacg
    12781 gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat ggtcgcattt
    12841 gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt cccttgataa
    12901 acataggcat tgtctactag cacacctaac catacacgat tgacagcagt aaattcaagg
    12961 gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga atcttctcct
    13021 gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac tgtagaagac
    13081 tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc ttctacttta
    13141 agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca agtcatatag
    13201 cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg aagacttgtc
    13261 caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt acttactgtt
    13321 tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc aaaaacatcg
    13381 actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa tgcccgcacg
    13441 taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa ataacgtttt
    13501 tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag gcgtgcttgc
    13561 cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt ctgtttgatt
    13621 ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg acaaaagtca
    13681 tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc ggtcacaagt
    13741 cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg actcggagtt
    13801 aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc ctcggtatta
    13861 gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta atactcaggt
    13921 caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta
    13981 ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt tcttattact
    14041 tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag tagcttcttc
    14101 ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    14161 tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat tttattttaa
    14221 tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt ttccaacaca
    14281 actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc taaaacgaaa
    14341 tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa ctcgctgaag
    14401 gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg gatcgaatcg
    14461 atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt aaattgattg
    14521 gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt cttcttcagc
    14581 aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat gatttctttg
    14641 actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc aaagtgaaat
    14701 tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg attgtacatc
    14761 gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt gattgctgtt
    14821 ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt aataccaagt
    14881 acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat ttcttttgtg
    14941 ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc ttcttggttt
    15001 tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa taaaaccata
    15061 ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt gattttgtcg
    15121 atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata caagttattt
    15181 agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat ttcctgaccg
    15241 atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg tacaaaatcg
    15301 atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata gctggttttc
    15361 gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg aaagacatca
    15421 ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc tggaactttc
    15481 accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata attcgtactg
    15541 aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt caaaccgttt
    15601 ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt attcatttgc
    15661 atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta cttgttgtat
    15721 ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata attttgtttc
    15781 cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt ctagagaaag
    15841 cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg ttatttcacc
    15901 atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc ggttcttttc
    15961 atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac tagaggcata
    16021 ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag gaaaaccgcc
    16081 aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat acacatttgt
    16141 ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc gttccttcac
    16201 gatattcact tgaggttggg tataaaacag atctggataa actgtttccc gcgactcaaa
    16261 tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga caacaaaaat
    16321 gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac tagcagtgat
    16381 cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc tgttttcaaa
    16441 ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca aactttccaa
    16501 atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact gatgattttt
    16561 aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa aaaggtttgg
    16621 atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat gtaaatttcc
    16681 tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt gcgcacttaa
    16741 ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga gaagtgaacg
    16801 tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc ggatcgtttt
    16861 gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat acaccatatt
    16921 tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca acctgccttt
    16981 tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt tttctaaatg
    17041 atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga cggctaaaag
    17101 cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa aagaagggag
    17161 ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc ttggatcttg
    17221 ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg gtgcaaggct
    17281 tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct gatttagaag
    17341 gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg tttggtaacg
    17401 ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta gttgtcaaag
    17461 cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg gaagaaactc
    17521 ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa gtggcagaag
    17581 acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa taaagaatct
    17641 aaaaaaaaag aaagccgatt ttcagtgtcg gctttctttt tttagattct taacttgcta
    17701 cttgttcctt tttcatgtcg atatgtggaa tatcatcttc caaatacaca tctgagattg
    17761 ccttgaatcc aaacgactca taaaaagctt gtaggtattc ttgtgcgccg atcacgattg
    17821 gtttttctgg aaaatttttc tggatcatgt taatcgtttc ttgaacaatc tttcttccta
    17881 aaccatcttt acggttgtcc tgatgaacaa ggacacgtcc aaaatggata ctctccgctt
    17941 cttcatatac tcgcgtgtag gcaaggatct tcccatcagt atcttgaaaa aacgtatgcc
    18001 aagcttctcc atcaatgtca tcaacttctt gataaggaca ctgttgttcc acaacaaaaa
    18061 ctgcgattcg ttctttgacg atcgcgtaaa actctgctgt tgacaattct tcaaatttct
    18121 ttacctgata ttccactaag caaacgcccc ctgctttttt attcttagca taccgattcg
    18181 cacacaaaaa agcaaacgaa ccttacgaat ctcaggctcg tttgcttttt aaactgcttc
    18241 agttaaaaat tcgatctcaa ctgtccgagt aagtacatct gaatagctgt aagatactcg
    18301 ttcaaaagaa ttttcttcag gatccaaatc aacaacgaat actgaaggat aggtttctgt
    18361 taaaacgccg cggcgttctg tttgacgctt tcttcctgtc tgagcaacca acatgattgg
    18421 gctgccgata cgaccttcta aatctttctt gattgaagct aaagttgttg gcatacagtt
    18481 cacctctact atcaactata ccacatattt t
//
LOCUS       DARBDN010000050        18196 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000050 DARBDN010000000
VERSION     DARBDN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.050"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..152
                     /locus_tag="SCH06_001696"
     CDS             <1..152
                     /locus_tag="SCH06_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078260.1"
                     /translation="NFAKNQGYNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIY
                     MKKTL"
     gene            complement(230..763)
                     /locus_tag="SCH06_001697"
     CDS             complement(230..763)
                     /locus_tag="SCH06_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEG1078261.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(857..2035)
                     /gene="mutY"
                     /locus_tag="SCH06_001698"
     CDS             complement(857..2035)
                     /gene="mutY"
                     /locus_tag="SCH06_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEG1078262.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2028..2825)
                     /gene="recX"
                     /locus_tag="SCH06_001699"
     CDS             complement(2028..2825)
                     /gene="recX"
                     /locus_tag="SCH06_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEG1078263.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            2932..4314
                     /gene="rlmD"
                     /locus_tag="SCH06_001700"
     CDS             2932..4314
                     /gene="rlmD"
                     /locus_tag="SCH06_001700"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEG1078264.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4488..5066)
                     /locus_tag="SCH06_001701"
     CDS             complement(4488..5066)
                     /locus_tag="SCH06_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HEG1078265.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5388..5858
                     /locus_tag="SCH06_001702"
     CDS             5388..5858
                     /locus_tag="SCH06_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HEG1078266.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLTMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(5966..7192)
                     /locus_tag="SCH06_001703"
     CDS             complement(5966..7192)
                     /locus_tag="SCH06_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEG1078267.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(7946..8146)
                     /locus_tag="SCH06_001704"
     CDS             complement(7946..8146)
                     /locus_tag="SCH06_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEG1078268.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8280..8888)
                     /locus_tag="SCH06_001705"
     CDS             complement(8280..8888)
                     /locus_tag="SCH06_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEG1078269.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(8973..9443)
                     /locus_tag="SCH06_001706"
     CDS             complement(8973..9443)
                     /locus_tag="SCH06_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEG1078270.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9491..10405)
                     /locus_tag="SCH06_001707"
     CDS             complement(9491..10405)
                     /locus_tag="SCH06_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEG1078271.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10551..11354
                     /locus_tag="SCH06_001708"
     CDS             10551..11354
                     /locus_tag="SCH06_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEG1078272.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11532..12479
                     /locus_tag="SCH06_001709"
     CDS             11532..12479
                     /locus_tag="SCH06_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HEG1078273.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(12547..12840)
                     /locus_tag="SCH06_001710"
     CDS             complement(12547..12840)
                     /locus_tag="SCH06_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HEG1078274.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(12868..13533)
                     /locus_tag="SCH06_001711"
     CDS             complement(12868..13533)
                     /locus_tag="SCH06_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEG1078275.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(13673..14305)
                     /locus_tag="SCH06_001712"
     CDS             complement(13673..14305)
                     /locus_tag="SCH06_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078276.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(14312..15379)
                     /locus_tag="SCH06_001713"
     CDS             complement(14312..15379)
                     /locus_tag="SCH06_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1078277.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(15376..16107)
                     /locus_tag="SCH06_001714"
     CDS             complement(15376..16107)
                     /locus_tag="SCH06_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEG1078278.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(16276..16755)
                     /gene="greA"
                     /locus_tag="SCH06_001715"
     CDS             complement(16276..16755)
                     /gene="greA"
                     /locus_tag="SCH06_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEG1078279.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(16891..18066)
                     /gene="mltG"
                     /locus_tag="SCH06_001716"
     CDS             complement(16891..18066)
                     /gene="mltG"
                     /locus_tag="SCH06_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEG1078280.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT         5405 a         3687 c         2908 g         6196 t
ORIGIN      
        1 aaaactttgc taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg
       61 aaacttttta cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca
      121 tgcctcatat ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca
      181 gcaagctttt gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg
      241 acaattgctt gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc
      301 cattattgat ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt
      361 tcgggtaatt catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct
      421 cgccgtcagg aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt
      481 ccagcaaaaa aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg
      541 ctattacatt gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc
      601 atcggcgtcc atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt
      661 cgcttgtttt taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt
      721 aactttggat cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag
      781 cagcattttg tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa
      841 taaaaatgag ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta
      901 ccagtttcat ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact
      961 tcgaagtttt gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa
     1021 ggagaacatg ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct
     1081 gccaaacaaa gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt
     1141 catcaaacag atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct
     1201 cttgtgtcac ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc
     1261 tttcttcaaa ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt
     1321 cttttggctt tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag
     1381 ctaaacaaaa ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag
     1441 ctgaacctag atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt
     1501 tccgcatcgc ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc
     1561 aaaacaatct gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa
     1621 atgcgatact tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt
     1681 cttcaggcgt ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt
     1741 ggatgttccg ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt
     1801 ctggagcatt tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat
     1861 cgatcactgt gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag
     1921 gatcacgatt atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact
     1981 gatcttgaaa ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc
     2041 tcttcctttt ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag
     2101 ctttgcttta cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt
     2161 ttatctcctt gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga
     2221 tcagctatcg cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg
     2281 atttttctca ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct
     2341 gtctgatgtg cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg
     2401 atttcaggtt tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca
     2461 cttaagcgca tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc
     2521 aattctttta agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt
     2581 aagtatgttc ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg
     2641 tgaaaaccga aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat
     2701 tcccgtcctt ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct
     2761 ccttcagata aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt
     2821 aacataaaca tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc
     2881 aggtattata tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa
     2941 acaattgtca aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt
     3001 gaaggaatcg gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa
     3061 gaagtactag tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa
     3121 gtcaaaaaaa caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt
     3181 ggctgtcaat tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt
     3241 ttgcaagcat tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg
     3301 atcgggatgg atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat
     3361 aagcagactc aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct
     3421 ataacagact gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa
     3481 ctattgaata aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc
     3541 acaatcatgg ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc
     3601 agtaaaaaat tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa
     3661 gttgtttcaa tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa
     3721 acgatccact tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat
     3781 ctttctcctc gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa
     3841 ggaatcaaag cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt
     3901 gggacgatcg gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt
     3961 cctcaagcaa tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga
     4021 tatgaagtcg ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct
     4081 gatggtatca tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta
     4141 ttgaaatacc ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga
     4201 gatctggtta atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt
     4261 cctcagactg cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa
     4321 gaggttgtga aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc
     4381 ttcatgtttt atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt
     4441 taaaaaaagg gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc
     4501 acgtctatca cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc
     4561 acattatatc cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga
     4621 acagttgctt tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga
     4681 ttaggattcc aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct
     4741 gttaaattcc aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta
     4801 gatgtctgtt catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca
     4861 atgaatgtat ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt
     4921 tgatttaagt ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata
     4981 taaccatgcg caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata
     5041 aacaataacg tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta
     5101 aacgctttat tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa
     5161 ggtgaaaaaa gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa
     5221 catgagaatc aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa
     5281 ctttttaata acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg
     5341 ctgtgagcct tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa
     5401 aagatattcg tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt
     5461 tgcttagcgg aaatcccgga aaatattact attctttgca acttccacca tttgcaccac
     5521 ctagctggat atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt
     5581 atttgttact taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga
     5641 ttcagttcat ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca
     5701 ttgcagcaat cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt
     5761 ggctgcatca tcgcctgaca atgtggctca tgattcctta ttatttatgg gtactattcg
     5821 caactctatt gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt
     5881 aatttaacac atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac
     5941 tctttattaa ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct
     6001 ggtcataacc ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt
     6061 gacttggtgt atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt
     6121 ggtactgatc atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg
     6181 atccatcacc gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat
     6241 tctcattttt caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt
     6301 cattttggat cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca
     6361 tttgtccttc gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg
     6421 tcgctacatc aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt
     6481 ttaaaatttt tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg
     6541 tcactacttc ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca
     6601 ttcgagaata ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga
     6661 caccatccaa agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca
     6721 aatcttccat gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt
     6781 gctcaattga atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat
     6841 ctaccgttcc ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg
     6901 attttttttg tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg
     6961 ttcttcctaa tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat
     7021 caatgcttac tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt
     7081 ttactgtttg gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca
     7141 gcaaaacgaa tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc
     7201 tctgtttcac attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt
     7261 ttaatcataa gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt
     7321 ctcaaaattc ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca
     7381 gttcgcaatc gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta
     7441 ttttccaaat aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc
     7501 tttgcctacc gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct
     7561 tttgttaaac ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga
     7621 ctcgaactag tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag
     7681 taaaacgatt ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg
     7741 tttcacaaat ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact
     7801 aacgaagaaa atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat
     7861 ttacttagcc aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga
     7921 agtcgtgtct ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc
     7981 gtgcaccttc aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt
     8041 ctccttgaat tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc
     8101 caaatccttt ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc
     8161 caaaaaagtt cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc
     8221 aagctttcgc tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt
     8281 tattttgctg cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct
     8341 gcaatataat ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc
     8401 aaacctagaa ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta
     8461 atagctaatt ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg
     8521 gctgcttttt tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct
     8581 tcttttattt ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat
     8641 gaatggttag catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata
     8701 gcgtccatat cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca
     8761 attgctgaat ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc
     8821 gtttcttcgt caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg
     8881 taagtcataa aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta
     8941 acaaagagaa ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact
     9001 tcttcttcaa aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca
     9061 aggataacaa taatttgagt gatgattttc gccacatact cattgctgtt cataacattg
     9121 atcaacaata ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac
     9181 ttaccgcatt caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt
     9241 ttgttcgtta caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc
     9301 atacttaaat caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc
     9361 aaaccaccaa aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct
     9421 tttaactgtc gatactgctt catgagccaa cctaccttat taaaaattct tatttatcat
     9481 actctatatt tcaataactt tcatctttat ttaaaaaaat taattttttt tgatcctttg
     9541 cctttgtctc tgcttggatc gtcacatgtg taataccata ttttaatttt aataaagaaa
     9601 ttatacgagg atatatcttt tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc
     9661 cgtcgaaaat aattatcttt tcgctatact gccaaatatg gacatgatga acatccttta
     9721 ccccatcgat tgcttcaatt tcttgttcca ttttttcata gtcgatagca ggtgcacttt
     9781 gtatcaaaat agcggcagct tttttgatca ccattatcgc ttctatcaat atatatatcg
     9841 aaatgatcag tgtaataact ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg
     9901 ctccgataat cacacttacc gaagacagtg tatcacttaa caaatgcaaa taactagatt
     9961 ttatattcaa actttcatct gcttcttgtc gtaataataa tactgagaac aaattcgcga
    10021 gcaatccaat aactgctact gttagcatca aatgactatt tatcttttct ggtgaagtga
    10081 accgcttgaa tgcttcaacg gttaaaaaca aggataatat gatcaatatg aatgagttga
    10141 tgaaagcact caatatttct aaacgctggt agccatacgt acgtttttta tttgcttctt
    10201 ttcgggccat tttttgtgcc ccgtaagaaa aaataattgc caatgtatca ctaaggttat
    10261 ggaaagcatc tgaaacaaga gacaaactcc ctgacataat ccctccaata aattctgata
    10321 aagtgatcac cgcattcaaa accactactc caaatagttt ttttgatgat ctctgtggct
    10381 gtgtaggcac tattccttcc tccattttat ttatattgga tagtctttag acaagaataa
    10441 catttttttg atatttcacc aatcattcag ctgtttcctt aaagcacttg tatttcactt
    10501 gatacttcgc tagaattgca agtgatgaca ctactagatg aggagtactt atgacaacaa
    10561 aacaattaat tatcagttcc tttatacgat tcaaagacct aaaggaggcg agaaatgtcc
    10621 cattttggaa agccattgtc tatcttttag ttttgagtat aattatggct ttgccaatct
    10681 cttttcaagt ttttcaagtc ttaaacaaca ttcaattgga tgggcaaaag attgctactc
    10741 gcattcctga ttttacaatc caaaacgggc agcttcaaac cgaagaaaaa gaaggattca
    10801 tttaccaaac aaactccatt atcttcacat ttgatccaga gggaaaacga acagaacagg
    10861 acatctctac tgatttgatg gggaattttg ttagtgtcgg gatgttaaaa aacaaactta
    10921 tcatagctct tcctaataca ggcacgactt ctgctttgtt gaacaataac caattagaac
    10981 ttccctacac caatgaatct ttaaaaaact taacaggtaa gcagctccgt tcttttttaa
    11041 gtgaagcatc tataccactt tggataaaag tcctgacatt tatattttct atttatccta
    11101 gttttctgaa tctgctgatc actttgctat ttaccaacat tgctgctttt ctctatgcac
    11161 gctttcgact aacaaaagct acttttcttg attgtttaaa aacattgatc tattcaattt
    11221 cattgcctac tataattgca acaatcttga tggtctttct tccttctttt gacactagcg
    11281 ccttcattgc ttttgcagga atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa
    11341 tatcgatcaa ttaagaaata aagacaactc gttatttcta cttcaataga cccttttaga
    11401 ggttgtgaca tttttttgtc acagcccctt ttttatttga aaaatatttc tttctcaaaa
    11461 aacaagcaag gcgcttcaaa gttcttcttg tatgcgctac acttagagta aagaaaggcg
    11521 ggaaattaac tatgtcagaa agaatcattt atgcagatcg tccatttcgt gatgaattta
    11581 tcgaagaaat ccatactata gcgcctggtt atatctttaa aacagaatta caaccagagg
    11641 atctacaaaa tgtagagatc agtttgggct ggaactcaga ctaccaagaa aaactattag
    11701 cctcttctac cttgaaatgg gtccaatcta tctcagctgg tgttgatcag ctaccccttg
    11761 agactttttc aaagaaacat attttacttt caaatggtag tggcatccac agtgaatcga
    11821 ttacggagca tgtcttagga atcatccttg ggtattctcg tggtcttttt caagcacaaa
    11881 aggcacagag tgacatgaaa tggttaggtt catcggtcca ttaccaatct atccaaggga
    11941 aaaaaatact aatcattgga actggccata ttggaaaaat gattgcaaaa aaatgcaaag
    12001 cattagacat gaactgctat ggaatcaata catccggtca tccagcagaa ggaatggaaa
    12061 agactttttc tttaaatcaa ctaaaggaag ttcttcctga agtagatttc gtagtcaata
    12121 tcttacctct aacggaggaa acaactgggc tctttgatca gcatatgttt gaacactttg
    12181 atccaaaatc tgtattcatc aatgttggcc gtggtgcttc tgttaagaca caagatctgg
    12241 tgcaggcttt aaataaccag caactttcct ttgcagcatt agacgttttt gaggaagagc
    12301 ctcttccaca agatcatcct ctttggaaaa tggacaatgt actgattact tcccacattg
    12361 caggtttgac acctgatttt caaaagaaat taatggctat ttttttaacc aatctgaaaa
    12421 gctactttgc cacccatgag cttcaaacca atcaagtaaa attgtctgca ggatattaat
    12481 agctgaaaac aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct
    12541 ctttttttat tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac
    12601 aagtaaatca tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc
    12661 atccatttcc actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa
    12721 accatcatga acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc
    12781 tggcagatca atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat
    12841 cccaacaacc tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac
    12901 atcgcctgtc tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc
    12961 aggagaagcg ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg
    13021 ttgcctgaaa tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat
    13081 ttctgctaaa gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa
    13141 attatgcgca atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat
    13201 cttttcaagt actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc
    13261 catttccttt accatcagag taactaagat actggcttga atatcttctc caatagcgac
    13321 aattacatga tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt
    13381 tgccacaaca gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc
    13441 aatagccagt acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg
    13501 tccaagacct acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt
    13561 ctcagtataa caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa
    13621 gaaaaataat agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca
    13681 ccaaaccatg tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag
    13741 ccaatatatt ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta
    13801 tttcctgatt actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta
    13861 gttcttcatg taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca
    13921 cttctggttc taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat
    13981 gtgcggtaga ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt
    14041 tttcgtcatc aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga
    14101 ttgcttttgt tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt
    14161 ccggtcgaag tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta
    14221 cttcaatgtc ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt
    14281 catctactaa taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga
    14341 tttctacact tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag
    14401 ctactcgttc tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa
    14461 accctgttcc gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata
    14521 cctctaattc attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc
    14581 ggaacaagtg atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg
    14641 aaatctggat tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt
    14701 tctcttctaa attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag
    14761 cgttgatgat ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt
    14821 tttctgcttg ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa
    14881 ctgaatcatg cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg
    14941 tttgtccatc tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa
    15001 tcattttttc ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg
    15061 atgcacttgg gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac
    15121 gcagcttttc ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga
    15181 caattaatcc tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata
    15241 aacgtgcacg cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga
    15301 aaagtgaaaa tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc
    15361 tggatatttt tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat
    15421 aatcttcaat ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt
    15481 tttcaaagaa aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa
    15541 tcggatggct acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat
    15601 cacaatatta tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga
    15661 aatgacggcg atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc
    15721 gaataattgc tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat
    15781 catgatctgt ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac
    15841 acctttcaga ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt
    15901 gactaagcta aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt
    15961 acgaggatgt ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa
    16021 aagtccagta ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac
    16081 cacaaaaaaa cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc
    16141 atcataccta tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa
    16201 atctaaaata cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta
    16261 gatctttcag tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc
    16321 tggagtagca atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg
    16381 agaatcattg gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta
    16441 ctcttcttct tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc
    16501 atctgcatct acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt
    16561 tgtgattctt ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc
    16621 ggaaagatct ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac
    16681 tgtttttagt tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata
    16741 aactttctct accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct
    16801 tttgaggaat atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct
    16861 aaaaatgatc aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa
    16921 ttccatatgt tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac
    16981 gaaataataa tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg
    17041 attgtcaaaa ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac
    17101 agctgtatct tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat
    17161 atctgactga agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt
    17221 acgatcattt tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg
    17281 tacagtcaaa tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt
    17341 gttcaccatt tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc
    17401 tgggaataag taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa
    17461 cagttctggg aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa
    17521 aaattctttc ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc
    17581 gtacccttct ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc
    17641 ttcttgcaac tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc
    17701 agcttgaaag ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt
    17761 aataatattg tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat
    17821 ctcgacttgg actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata
    17881 acgatacacg gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa
    17941 aatgatcttc ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat
    18001 atctgctgta gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc
    18061 tgacaaaaca actcctcctt actatcaagt tcgtaacttt attcattata catgatattt
    18121 gaattggcgt gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt
    18181 actataagat taaaat
//
LOCUS       DARBDN010000051        17635 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000051 DARBDN010000000
VERSION     DARBDN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.051"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            289..528
                     /locus_tag="SCH06_001717"
     CDS             289..528
                     /locus_tag="SCH06_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078281.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(890..1150)
                     /locus_tag="SCH06_001718"
     CDS             complement(890..1150)
                     /locus_tag="SCH06_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078282.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1335..1832)
                     /locus_tag="SCH06_001719"
     CDS             complement(1335..1832)
                     /locus_tag="SCH06_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEG1078283.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1962..2672)
                     /gene="budA"
                     /locus_tag="SCH06_001720"
     CDS             complement(1962..2672)
                     /gene="budA"
                     /locus_tag="SCH06_001720"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEG1078284.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNIQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2685..4349)
                     /gene="alsS"
                     /locus_tag="SCH06_001721"
     CDS             complement(2685..4349)
                     /gene="alsS"
                     /locus_tag="SCH06_001721"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HEG1078285.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4557..5219)
                     /locus_tag="SCH06_001722"
     CDS             complement(4557..5219)
                     /locus_tag="SCH06_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEG1078286.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKENSFSPVRLFIKMFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSTNCWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5229..6044)
                     /locus_tag="SCH06_001723"
     CDS             complement(5229..6044)
                     /locus_tag="SCH06_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1078287.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6305..6748)
                     /locus_tag="SCH06_001724"
     CDS             complement(6305..6748)
                     /locus_tag="SCH06_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HEG1078288.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     HSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6882..7220)
                     /locus_tag="SCH06_001725"
                     /pseudo
     CDS             complement(6882..7220)
                     /locus_tag="SCH06_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(7208..7585)
                     /locus_tag="SCH06_001726"
     CDS             complement(7208..7585)
                     /locus_tag="SCH06_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEG1078289.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7809..9002
                     /locus_tag="SCH06_001727"
     CDS             7809..9002
                     /locus_tag="SCH06_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1078290.1"
                     /translation="MTTYQRKVLVSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFVMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9168..9590)
                     /locus_tag="SCH06_001728"
     CDS             complement(9168..9590)
                     /locus_tag="SCH06_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1078291.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQQYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10173..10667
                     /locus_tag="SCH06_001729"
     CDS             10173..10667
                     /locus_tag="SCH06_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078292.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQAA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10829..12001)
                     /locus_tag="SCH06_001730"
     CDS             complement(10829..12001)
                     /locus_tag="SCH06_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEG1078293.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEGSSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12207..13022)
                     /locus_tag="SCH06_001731"
     CDS             complement(12207..13022)
                     /locus_tag="SCH06_001731"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEG1078294.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13172..13618)
                     /locus_tag="SCH06_001732"
     CDS             complement(13172..13618)
                     /locus_tag="SCH06_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEG1078295.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13615..14619)
                     /locus_tag="SCH06_001733"
     CDS             complement(13615..14619)
                     /locus_tag="SCH06_001733"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEG1078296.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14659..14988)
                     /locus_tag="SCH06_001734"
     CDS             complement(14659..14988)
                     /locus_tag="SCH06_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEG1078297.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(15114..17441)
                     /locus_tag="SCH06_001735"
     CDS             complement(15114..17441)
                     /locus_tag="SCH06_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1078298.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5098 a         3484 c         3069 g         5984 t
ORIGIN      
        1 caaaagctat cctcctagca actatttaaa tacccaaaaa aattacctct agataatatc
       61 atacctacgt tttcacttat aaattttttc ataaaaaaag cgtttagagg cataatcgtt
      121 aatacagatg gtaaccaatg tatctggttt gaactgggat atcaccctct ccatatatgt
      181 attactaaga ctaatagata ctataaaaga cttgatagtt ttgcattgat tttgcctaat
      241 actgagcata ggtgtatgct aaacgatact ataaggagtg tgtacataat gaaaagaatt
      301 ctgtttatca gtttatcaaa tttattgtta cttactgctt gtgggacttc tgcatcaaag
      361 aacatacctt cagatacgca aatttcgaat agtatcgatt caacaatttc tacaaatgag
      421 aaaaattctc cggtagaaac ttccgatata aaagtttcta cctctgcaaa aaacagggta
      481 aagaaactgt cagcacgtct cctttatttc aaacaaactc tgaattagct tcttcatctt
      541 cttcagcaaa taatgatgat agtttcgcgt ttactcctaa ctaaatgcaa cctttacaaa
      601 tgctttacga taacaagcct gagctaaatg atcctgatat cagttttgca ttttttgaaa
      661 tgattggatc ggatgatctt tttaaaacta ctagtttgtc tatccgaaaa taggacagtt
      721 ctggcagtat aggtttttat cgagtttctc caccaggcct cgttacagag acagattctc
      781 taggcgaacc ttttgaataa atcaaaaatc atgaacaatc actgccaact aaataaagtg
      841 ccttcaaaag cttggtcttc tcgcttttga aggcacttta tttaaatctt tatgaaacta
      901 aagtatgttc atatttgttg ctatagttat atagatattc tgttgtttcc aactcataaa
      961 cgtgagtata ttttgccact acttttccgc atttttctaa tatttcattg cgatcgacgt
     1021 catgatattc gtctacgcag atcacaacac aattttctaa tttactgatt acttctccaa
     1081 ccactttttg tttcaagcca ataggttggc aaatatattt ttttcctaaa atgatagttt
     1141 cgttattcat atttcatcca tccttaatgt tttttcatta ttcaaaatga taataccatt
     1201 aaaatatgat tgtgaaaatc aataacactt gtgattttat aaaaaaataa aaaaaccgaa
     1261 aaacagaaat gaccactgtc tttccggctc tttttattct tgatttctct tcttttttgt
     1321 ttcaatagac gattttagtt attaataaat gaaaaagcat ttatattaaa atttgctaat
     1381 aaaagatcta catatttttc tagaaatgct tgatcgattt catcataccc tttcgttact
     1441 ccgcaatcga tatctaaaac accgattaaa ttaccttctt ttaccattgg cactacgatt
     1501 tctgattgtg cggctgaatc gcaggaaatg taatttgcat gggttttgac atcatcaacg
     1561 atcaatgttt cttgtttttc agctgattct ccacaaactc cttttcccat cttgatacgt
     1621 gtgcaagaaa ctcgcccttg gaacggtcct aaaatcaatt cattaccatc gaataaataa
     1681 tatcctgcaa agacagtctc aggcaaagtc tcattcaaca atgcagatga atttgctaaa
     1741 tttgctaacc agttatcttc tgcttctaat aatccttgtt gctgtaataa taaaatttcg
     1801 tatgcatctt ttttctgttt ttctgtccac atgataaaaa ccgctccttt ttgatctatg
     1861 gagaagatta tagctcagtt tttttgtaaa cgctaggttt cctcctcaaa aaaacgagat
     1921 acgtcaggtt aatcaccttg aacgcatctc gctgtctttt tctattctgc ttgttggatt
     1981 tctgctgcta aatcagcata atcaatcgtt tcgtgaacaa aagtcggatc atcaactgga
     2041 aaatgctgta caagggacga gatgcggcta atctcaactt ttccttcagc cacttcaaaa
     2101 tccattacat gtccgccaaa tgtatgtgta tcatcgataa aatgcaggtg aaatcccgct
     2161 gcagcaactc cttggaataa ttcaggcgta aagaacccga ctaatgttcc ttggatattg
     2221 ctttgttgga attctggttg agactctgaa atttttgcta gtcttctgta aggtttttct
     2281 tgcttcggca tgatacggat gtgcatattt ttgaataatc cagttatctt cactgccaaa
     2341 aataggtttt ccccggcttc tcttactaat atgtcttttt tcaattgttc tccatctgca
     2401 gtttttgaga cagaaaaact agtatctggc gtaaaatctg taattgctgc atagggggta
     2461 agttcacttc catctaattg ggcaactgag ccatctgatc ttccttgata agctacgcca
     2521 tctaaaaaga tgacttcacc atcaagccca tgcaatgttc ccaatcccag agttcctttt
     2581 tctaatatat gagcaatcgt ttctgttcca tccatcaagc cggccatcaa agctcctaat
     2641 gtcccgtgct ggtataagat tttttcagtc atgtcgacac ttccttaata gaattgatct
     2701 ggtaagattg tttctcccaa tttctcatta tcacggtaat caatcggaat atcaataatt
     2761 acgggtcctt ctgtcgcaaa tccttcttct aaagcttttt ctaattcctc tacacttgta
     2821 gctcggattc ctttagcgcc aaaagcttct gcatatttca caaaatcaac tggaccaaag
     2881 tctacacctg acgcccgctg atatttcatt ttttcttgga actctaccat attgtagtgt
     2941 ccatcattcc aaatcaaatg aacgatattc aattttttac gtaccgccgt ttctaaatcc
     3001 tgggcagaga ataaaaatcc cccatcgccg gaaactgata cgatttgtgt atttggacgc
     3061 accaatgcag cagaaatcgc ccatggcaat gcaacaccaa gcgtttgcat accattactg
     3121 aataacaaat gacgaggttc ataacttcta aagtggcgtg ccatccaaat ataatgacta
     3181 cctacatcta cggtaacagt catatcatct gttacttttg actgaagcgt gttaataact
     3241 tctaaaggat gcaagatacc tgcttctcct tttgattgaa caatgtcccg ctccgttaat
     3301 tttgcttgaa gagatgctaa atattctttt gcatcttctg acacttgttg aggctctaat
     3361 gaacctgtca ataaatcaag agtggctgag atatcaccga tcaattctct ttcaggctgc
     3421 ataaaaggat cgatttcagc tggcgcttca tcgatcacaa tgatccgcgc atctttttcc
     3481 gcattccagt ttcttgcttc atattcgatt ggatcatagc caattgcaat aactagatca
     3541 cttcgtttca aaagcatatc tcctggttgg tttctaaata aacccacacg accaaagaaa
     3601 tgcgcttcta attcacgtga gatcactcca gctgcttgga atgtctctac aacaggcaat
     3661 gctgtctttt caactaattg cctgatggct aacgtttctt tttcacttga tcctcgcata
     3721 cctactaata gtaccggtag ttttgcttct ctaatgcgtt cagctaggta acggatatca
     3781 tctgcagaag cagaacctaa tttaggatcg ctcaatggct tgatgacatt accttggaca
     3841 ggtgcatcca ctacatcttg cgggatactg ataaagctcg cgcctttttt tgaactctta
     3901 gccatacgat aagcattggc aatcacttct gaaattgttt ctggatcttg gatttctgca
     3961 ctgtattttg tgattggctg gaacagtgct gcattatcca tgctttgatg ggtcaacttc
     4021 aatagatcgc ttcgttttac ttgtccggca attgctaaaa ctgggtcacc ttctgctgtc
     4081 gctgttacca aacctgtagc taagttacta gcaccaggac cacttgttgc gataactact
     4141 cctggctctc ctgtaatacg tccgattgct tgtgccataa atgcagcatt ttgttcgtga
     4201 cgagtcacga ttaattcagg accttgatcc tctaattcat taaatacacc atcgattttt
     4261 gcacctggta taccgaatac ataatcaaca tgatgattaa tcaaactttc tactacagat
     4321 ttcgaacctt gtttcatttt ttcagccatt gaacatcgtc ctttttatgc tttattttta
     4381 attattagtt agaaataatc acaaataagt gatacagttt ctaaacctgt ttcatacaaa
     4441 agtatagcac gttttatttc atttgtttag ccatatgttt caaaaaatga aaaagaatga
     4501 cagtttttac ataaaaaaaa ctgtcattct taattgaaag tttcaattta taaagtctac
     4561 agatccatag ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa
     4621 ggacctagta gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat
     4681 agtaaaaaat ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt
     4741 agaacttgat ttggtttcga cgctggattt ctcacctgaa aataccagca gttggtgcta
     4801 aaggaaactg ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa
     4861 aaacgtataa aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc
     4921 caataaaaaa atccctttag ccaaaattgg cgaaacatct ttatgaacaa acgtactggt
     4981 gaaaaactat tttcttttgc taattcttct gtcataccta tcatcacgat gcaacctgga
     5041 ccaataaaaa gtaaagaaaa aataaaggaa aagacattcc ttccatctat cgacaaaagg
     5101 aacgcagctg ctatatacaa gatattgaca caccaaaaac aaaggctact tgccaatgat
     5161 tgatacaacc aataaaagaa ttccatataa acatttttgt caaaacgctg ctctttcata
     5221 atcacctcct attccttcat tcctgatgaa gcgatccctt ctacaaaata tttttgcatc
     5281 gctaaaaata taaaagcaac aggaagaaca gaaacaactg aggcagccat gattaatgcg
     5341 tactctgcat caaatagccc aataaacatt ttcaacccta actggattgt tttattttcc
     5401 gtagaagaca aataaatgaa tggccccata taatcgttcc atgtattaac gaatgtgatg
     5461 atcgtcaaac tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg atagattccc
     5521 cactctgata agccatcgat ccgcgcactc tcacataaag aatctgggat actactgtaa
     5581 tattgcttca acaagaacac accaaaagca ttgaacgctt gtaatagcac caacgaccac
     5641 aacgtatctg ttaaacccac ttttctcatc ataatgaact gcgggatcat ataagactgc
     5701 caagggacag caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc tttaaaattt
     5761 agtttagaaa acccgtaagc agcaaaacta gaagtaaaca actgaatcaa cgtgatcaca
     5821 acgcttaaaa aagctgtatt cttaaaaaat gtcactaaag gaatacgaga ccaaataacc
     5881 agataattct ctaaatgcca agttttaggg atccattgaa tcggaatcgt gaacacttca
     5941 ttatttgctt tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt caataaagct
     6001 aatacaatca gcagaatcat acccaaccat tgaataaagg gcatgttttt tgaacgaatt
     6061 tttgcttttt ttctttcatt tcgaacacct ccaaagttat aatcttcatt tctttgtaat
     6121 gattacaatc cagaacaacg gttattatag ctgattcatt tccgttcttc ttatttttgt
     6181 aagcgcttat ttaacaagtt atgtaaatct ctttattttt ttgatttaaa aatgaaaaaa
     6241 tacaaaagca agactgtcat acgtctcgct tttgtattga aatttcttcg attagagata
     6301 cttattactg ttcaaaagct tctttgaaac ggtgaatcaa ttcattgact acaggtgata
     6361 aaatccgatt ctttttccag actagcatgc agttcgtttc aatcattggg tcaagcggaa
     6421 cgaatgtcac tcgctttgaa tgatgactta cagcaccttc tatgactaaa gcagcaccta
     6481 cctgattctc aattagcgca aatacattga aaatcaaatt gtacgttcct gtgatcagca
     6541 actgctcctt ttttatgcct aaccagtcag caaacattcg ctgtatttct ggacgctttg
     6601 agatcaaaag aggtacattc gcaaagtctt cttttgttat cacgtctttt tttgctaaaa
     6661 cagaattttc taaaatgagc aatccccatt tttcctttct tggtaacaaa atcgtttcgt
     6721 atttctctgt atctactgga tctagcaaaa tcgctaaatc taacaggctt ttttctagtc
     6781 actccgtgat atcatcactt gttccgctgt ggatatgaaa ttgaacgctg ggataatcac
     6841 ggatcaactt ttctagtaat agtgccaatg tattcgaact atcagcttcc acacagccga
     6901 tcgtaaatcg gccgctgaat aattgttttt ttctgttctc gaattcttga gtggtttgat
     6961 tcgttaaatc taaaatttct tctgctcggc ttttttagaa aataacctgc ttctgtcaag
     7021 atcattttgc ggttttcgcg tacaaacagt tctgttccta gttactcttc taactccttc
     7081 agttgtcggc ttaaggttgg ttgtgtaaga tgtagaactt ctgcggcttg agagattgtt
     7141 ccttcttctg caattgtcca aaaatatttt agtaagcgta actccatagc gatgctcctt
     7201 gattttttta cttgatacat tccattttat ttctagataa cacacgatca tatttcttga
     7261 tttttccttg taaacgttcc aaacattctt gcatttcagc aatttttttc gtcaaaagtt
     7321 cactttcttc aatcaaaagc ttacgccgct caaatacagt tgcttctcct tcgctagata
     7381 ggcgaatata ttcaatcaaa gactcgatcg ataatccggc atttcgcata cagatcgtaa
     7441 agtcgaccca ttttaggtct tcttctgtat aatcacggat tccgcctttt gtccgattaa
     7501 ctggtggaat caacccgatt cgttcataat agcgcaatgt atcggccgaa atgccctttt
     7561 cttcactgac ttgtttgata ttcatctgat cactctttct cttaatttct tgccacttta
     7621 cttatgtatt ttatttattc tacaacttta agtgtactcc aagtcaatac tcatttctat
     7681 taaaactaag ctggattatc tatatcggtt gtttgtgtat tatttcaaat aaaaaagtct
     7741 tgttttttta ttcttttttg gatatacttt taacaattta gggaaatttt aggaaaaggg
     7801 gtataaaaat gacaacgtat cagcgaaagg tattagtatc gacatcggcg ggaattgctt
     7861 tagagaatat ggatattatg tttttagctt tttcattatc ttcaatgatt acttcttttc
     7921 atattagtgg tacgcaagcg ggtttcattt caacgatcac taatttgggg atgctcattg
     7981 gaggtatttt ttttggcatc atagctgata aatatggacg tgtgaaagta ttttctcaaa
     8041 cggtccttct gttttcgatt gcttctttat tgatgtattt tgcttcaaac atctacttgg
     8101 tttatctctt tcgctttatc gcaggtgtag gagcgggagg agaatatggg gcgtgtatgt
     8161 ccttgatttc cgaaagtttt tcaaaaaaac aaattggacg agcttcttcg gttgctggta
     8221 ttggtgcgca ggtcggtgcg gctttggctg cgattttagc tgctgtgatc attccaacgt
     8281 ttggttggaa gatgttgtat gtcgtaggtg tactgccggt gttgatggtc ttgttcattc
     8341 gtcgcggctt gactgaacca aaggaattca aatctgtaca atctgccgaa aagaaaacca
     8401 aacttagcag actgtttgaa tcaaaacatc ttgcttggca aacatgtggc cttagtatca
     8461 tggtaactgt ccaaattgcc ggctattttg ggttaatgaa ttggctacct tcaattatgc
     8521 aaaatcgatt agggctttcg gtttctgggt cttcattgtg gatggtcagt actattttag
     8581 gcatgtcttt ggggatgatg acttttggca taatcatgga taaattgggg cctaaactag
     8641 ccttttcttt gtttttaatt tgttcatcct tatctgtcta tctacttgtg ttagcccata
     8701 gccagtggag tttggtagca gccgctgtga tagtcggcta ctttatcaat ggcatgtatg
     8761 gtggatatgg cgcagtgatt agtagtttgt atccaacaga aatccgcgcg acggcgaata
     8821 atttcgttat gaaccttgga cgagctgttg gtggtttttc ttctatcgtc atcggtttct
     8881 tgatggatca ttatagttta actgccgtaa tcttgttttt gagcggtatt tacctagtca
     8941 gtctgctggt cttgacaact cttactggtg ttacagcatt aagggaaagc ttgcagcatt
     9001 gatagttgag tctgtaaatg acaagaaaga ggtgtggaaa aagcttgcat ctgcggtaat
     9061 aagaccagcc aaatcaaaaa catgagacac tgtttccgtt tggctggtcg tattacttga
     9121 tgcagggcag ctttttcaac tgctaatttc cttctatctg gcggcgacta ttctttgacg
     9181 tccgtcattt caaagtactt tactaataac ttagcataac gaaaaactgt ggatacactc
     9241 gtatattgag cgtctgcata atcttccaaa tttttctcag gatgttgata catgaattca
     9301 atcaaatgat aattatatga ttttctgtag aaatgaagat aaataatgta gattgggaag
     9361 ttctcctgct tttccataga aaagcgccga ttattctcat tcttcaaaat gaccttatca
     9421 ggatattgtt ggaacaattc ttctaaatct gttagataat tcaagataga cttacttgat
     9481 accttcaatt cgttttgtag ttcttctatt gaacaccaac gttctgtttc aagcagtaaa
     9541 tgaatcattt taattttctt ttgagaaact tttgttaaaa aagtctgcat attttctcct
     9601 cctgtatcta ctttactata ctacatacaa gaaaaaaacg gatacaaata tcatattgtc
     9661 acaccgtcaa tagtgcataa acctgttatt atttctcttt ttttcctaag tattctattg
     9721 atatgaatca tttaatcgtt tattatataa atgtcaataa tctaataata aaataacgta
     9781 catattttat tattgcatac ttaataacag aactatagca aaaaatcccg tgtatcaaca
     9841 cgggattaga ttaagtttcc tcaatcacta ttcataacac aattattata acaagtaagt
     9901 aaacaattga aaaggacatt tattgaaaac ggttgttttt tacttaagga ggaaatttag
     9961 tgaaaaaatt agttgcgttg tttttggtcg caggaagttt gttgagtggg tgtggtgcta
    10021 ctacgtctac tactcaaagc acaagttcag ctcaggcttc cagcagcagt accacgatct
    10081 ccgaaagtac ggcagattca tcgaaagaac aaattgaaaa gaaaaaagaa gaagagaaac
    10141 aaaaagcgga aaaagctgca ctagaaaaaa aagtgacaga agcggaatct gctttgtcac
    10201 aagctgaagc aaatcctaca aaagaaaact atgcaactgc ttcagcagct atccaagcgc
    10261 tacctgaaaa caaacaagag ttgacaagcc gtcttgctgc aattgattcc acaatcaaag
    10321 caaaagaagc agaagaagaa cggaaaaagc aagaagaaat tgcacgacaa caagcagaac
    10381 aagcgcaaca agaagcaatc gcacagcaac aagcagaaca ggcgaggcaa gaagcaatcg
    10441 cacagcaaca agcagaacag gcgcgacagc aagcagcagc tgaacaggct tctcagcagg
    10501 cacaagccgc agctcctgag caaaataatg aacaaactgt ctatgtcaca ccgaccggtt
    10561 caaaatacca tacacataaa tgtggaaatg gtacgtatac ccctgccact ttaagcgaag
    10621 ctcaagctcg tggtttaacc ccttgctcca aatgttatgg aaactaattc aaaagttata
    10681 ctataataat aaaattcttc tgaaacataa aaaaatagaa gctggcgttc cagatagtaa
    10741 accaaaaata gcagtttaca cgtccatttc gtcagcttct ctcttttttc atttagtctg
    10801 ttccctctgc ttttttggac atcttcattc attctttctc aatcaaatag tacacctctt
    10861 tttcttttcg cagtttatat cttccttttt tcaatttcat tgaaaactgt ttcgaatgtt
    10921 tatgttttac atggatttta agcaggagct cctcatgttg caagcgatag ttcctgcctt
    10981 ttaaatcaga aaatctcact agtccgtatt catcagaagc tttcacaaat ggaacttttt
    11041 ctctagtaat atagtgtttg ccgttgagcg tttttacaga aaagaccatt ccttcgattg
    11101 gtcgtccgtt tgtgttcttt acataaaaag ataaaggata gtttcgctta gcgatggcca
    11161 aagaatctaa ataagcgatg agtagccaaa ctaagccgat tgatccaagt agtataccga
    11221 taaaccaaat aaaaaatttc cattttttcc attgatcaat tccttggatc gctttttttg
    11281 cctcttttgc ttgataagga atacgatgcc ccgtcacaag cagtcgatgt gtattgacca
    11341 tataaggagt gcaggtaagc aaagtcacga gatctctgcc tttttggata cccaaagaat
    11401 ctacttcgtc aggtaagacc acttggattt tttctacttg atacgccaat gtctttccat
    11461 tgatctggat gaaaaactgg tctccttttt tcaacttagg caaatctgta aataattttg
    11521 cttctgggag tccacgatgc ccagaaagaa cggcatgggt gtttttcccg ccagtcggat
    11581 aagaacttcc ttccaataat gacgttcctt tttgcaaaaa tatttccgtt gtctgatcga
    11641 atataggtaa gctgacattg atttttggga tttcgatgac tccaagcata tgttccataa
    11701 aaaaggcatt actaggtaaa tcttttaatg cttttgcatc aactgcttgg ttgaaactgc
    11761 ctatccctgg tgatacgttt tgctctgcca actgttggtt tttctttgtc attttttcct
    11821 gctgtttttt tatttcctct gaattcttat tcgatgcttg cttttgataa tggatgatca
    11881 tttgctgggc aagaaaatca ttcagtgaat cttctacaaa aggataagaa aagatcccga
    11941 tcccaacgac taaaatgatt gccatgaaga tgtccagtat tcttattctg cttttattca
    12001 tcatgtccac ctattttcta atatgtatat gaagaggttg tgaaatcagc gccttgacct
    12061 gagtattagc gaagcaaacg gcaaaatagt tcctcctatt ttgccgtttg ttgagcgaat
    12121 accaagagac cgaccacttg tcacaacctt tctccccatt tgaatcacta tcgtttattt
    12181 atcgtatgat ttttgtttcc aatagtttaa gcttctgttt cttgatggcg ttttttgaaa
    12241 tagatcactg ctcctccaac taaagcagta cctaccaaga tgaatacgat gatccccata
    12301 ccaccagttg aaggcaagat tcctttaggt tggttatcga tcgttgtttc atcagaagtt
    12361 gttggatcat catctactgt aaattcagtg tacgcagctt cattcttagg taatgcgtag
    12421 ccttctggtg cttttgtttc ttgaaggcag tatgcccctt gtttcagccc ttcgattgaa
    12481 aatttccctt ctgaatcaga aatcaatttc acttcttccc agtcagaacc tgtgacttca
    12541 tctgaccaag catatgggta ttctcctgag gcaaggtttg ctattttttt cattaattta
    12601 acagttggat cttttgctct tagaatagaa aattctgcat cggctaattt ttcttgcgtg
    12661 ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt ggacattttc tacagtaatc
    12721 gtgttatccg tagttgtatt ttcccgattg actacaccgt ttggattccc aagattggct
    12781 tcatctgcgc catggatgat accggttgtt tgttgcaatt ttccgttttt tactataaaa
    12841 gtagtttctt tttgtggatt ggttaattga taaccatctg gtgcttttgt ttcaactaaa
    12901 gtataattgc cgtctattaa tccattgaca ctgatggatc cttcagtatc agttgtgaat
    12961 gtcaacgctg actcagcagg atcatagaga gcgacaccag tgttttcatc aaaaccggtc
    13021 acgaattgat tctctgaatt tttgatctgg aattgcgccc ctgctaactt atctacccct
    13081 gaaaagttcc cagctttctg gattttgata ttgctttctt tgatgacatt tttagcatat
    13141 aggtgaatcg tgtctaaagg tttgtcaggg tctagggtaa gcttaacacg atatttggcg
    13201 acgtttcgac accgggcttt ggtgtttcta caaagacgta tacagcatct ttcccatcag
    13261 atttacctgg aagagtcagg ttagctaatc cttcaccaga agtcgttaca cttgcgaagg
    13321 gtgtagcgtc tgctggaact gctgtgtctt tacttggata gtacgtagca gtgatgtcat
    13381 atacgttgaa ttcaacgccg ttcaacggtt cgctattcgg aaatgtcaat tccgttccgt
    13441 tgtttatttg attttctggt gctgaagtga atttcaattt atgcaaatta accgtaacat
    13501 tttctggtgt aggtgatacg gctgcagaaa cctctgcagt tcctaggccg agaacgaaag
    13561 gaagcagcat gatagcagtt cctaaaaacg tccatatttt tgttttgatg tttttcattt
    13621 tatttccctc ctattgtttc ctttttgttg ttttttataa aaccaagctg tccctgttga
    13681 aaggactagc aataacccta aaattgagaa acctccaagc atctcttcgc ttgtttttgg
    13741 aaagcttcct ccattttttt catttgatgg accatttgtc tgcatctgaa ctggcgtttt
    13801 tccattattc gtcggatttg cttttggttc gttgatgatt tccaatggta taggatgaag
    13861 cggatcataa ctgccttttt caacttcaaa gagaatggtt gattgactca atatatatcc
    13921 tttaggcggt ttaatctcca ctagttcgta acttccaaaa gacaatccat ggacagaaaa
    13981 tgttccatct ttactggaag taaaaatcgt tgctcttgaa tcatctttgg ctacccaatg
    14041 atttatcccg ttttcttgcg ctaagtattg gtcatttttt ttgactagaa attgagcatc
    14101 tgctagtttt tgtttcgttt gccgatccac tttgacaaat tgtttgcctc ctgtttggat
    14161 ggcaagatgt gtttctactg tttgattgtc agtcgtcaaa cgtacatcgt tatcaaatgt
    14221 cgttttttca ctgttttctt tcaatgtcat ttggtaacgg atcgttaatt tttttccagc
    14281 aaacgaacta agatcttttc cagaatctga taagacaaaa ccatgtttta ttttttgtgt
    14341 gtgaaatgta tgaatcttgt ctccaccaat caaaaaatcg atcgtttctg gttctagcca
    14401 taactgagga tcagctgtat ctttgatcgt ataggttcct atctcgttga tgttctcagg
    14461 aattgttacg gtgatgagat aagggacttt atccccatct gcaaaatctg tctgcttatt
    14521 ctctactgtt tttgttaatg tgagtgcagc aggtattttt tgttcgctct ttggatacaa
    14581 gtggatggtc gtcaatttat gattagatga atctgtcaca ggaagcacaa cgacaaatgg
    14641 tgctgatttt tcttttactt aatctgaagt ctttatttcc gtaaatcggt aaacagcgtc
    14701 acgaccttgc tcatctttgt ccgatgcact aaaagaagca atgccctctt cctcgtctac
    14761 tgtttttgtc acattttctg ccagtatttt ttcactatca cttttttgtg ctagttttct
    14821 ttgtgcgtct tccacactac ttccttctga ccgcagcttg taaaattcat ccgagacatc
    14881 atatatagcg aaagtaacgc cgttcaaccc ttttactcct tgaaagttat ccgggatatt
    14941 tattccgtcg ttttgactga tacttggcat cttatcgctt tcgaacattc gattatgcaa
    15001 agtaaatgta ataggtgatt ctctagctga cacagtcgga gaacctataa aaaagaccag
    15061 taggataaaa aagagaacag caaatatatc cacacgtaca ttttttgttt ttttcatcgc
    15121 tgttcacctg cttttttctt acgatggata aaataaaaga agccagaaaa aataaagatc
    15181 agtcctaaaa agacaaaggg cagtagacct atcccacctg tcgaaggaag caagagagtc
    15241 ggattgatcg tcaacttagc ggtatctgtt gcgataatcg tataattatt gtttacactt
    15301 ccttcgccta aactaatcgt tactatttgt gatccaatat ctgtccggct gttaactgtt
    15361 agggtataat ccaatgattc gcctaagaca acaccggtaa cgtggagatt tccaaccgaa
    15421 atcgagtgac tttgggcatc ataattaaag gcagcgtcat cgacagtaat cactgcgtta
    15481 gctttataga tggtataagt tcctgatgtg ttggctatat cagtaaatga caacttggga
    15541 tttgctgctt tgactttgtc tattccgcta ttcgttagtt taattgtata gctgccagca
    15601 ttaaccatat tttttgctga ttgtgcatct gctgtgtaat ccatactgct aagtgccact
    15661 tgtactggag taagcgaact agtgacaccc tctgctagct tgacatggat tgacgggaca
    15721 cctgcttttc catcatatgt cttactgcca ctgagctcta ccgcaccgct gatttgctta
    15781 atcgtataga catcagatgt ctgcacgata gtaaataaat agtttgttct ggcagctagt
    15841 ttagctagtc cgctttttgt caattgccaa gacgtatagg ttccaatttc agtaggcgca
    15901 gttacttcaa ctcccttttc attcatcgct ttgaaatcag ttggattcca tgtgatttga
    15961 tcaatactga gatcattgtt taaaagggat gttgattctg ttttatcatt aaaggcatat
    16021 ttaacgatcg gtacaacaga aagaccatca tagtacttac tgccatttgc attgattgat
    16081 actgttgcat ttgtcttata atataggatg acttcagaaa tctgttttcc atttgcgtcc
    16141 tttacgatta catttccatt tgtatctaaa ctagctaaaa cactcattgc tgattggttc
    16201 tttgtttcta tcgctgaaac agctgtaaag gtatatccgt tgatagtagg cgtattagtc
    16261 gtcaggtctt gtgcagcact tccgtaagta agattcatta ttttagaagg agcaatcatc
    16321 tgtccaaaat agtcttgata cttaatagtg attggtgttt gtttgcctgt ataggtcacc
    16381 gtatcgacgt tactttctag ggctgtgaaa gaaccgtttg tttgtgcaaa agaatagccc
    16441 gttactgctg ttggagtgat aaccactttg tcacccacat ggattccaga taatgtagtc
    16501 ccgtacgttc cgatttttgc tgctccacca ttgactgtat aagaaaaagt tcctgtccga
    16561 ttcgcattga cctgaaccgt tgctgcttga taggttggaa aatttgaaac atttccctta
    16621 ccatcaacga tctgcccatt tttgatcgag taccccgtga atggaatatc atttgctaac
    16681 tgtataccga ttgaaaaagt actcatacct cctccggcag gaagccctcc ccatgttgag
    16741 ggtgtaaaag aataactttt atccgcattg ggtgtaactg aatcgatcgt atttccagcg
    16801 gtagccaccc ccatatagat actttttggg aatgtgatag tagtaccatt tactgtggag
    16861 ccaataaaca gattatggat atctggacgg ttatcaataa aagcgattgc tttggttacg
    16921 ccttgtaacg cagttttatc cgcactcatc gatccgttaa ccgcaacaat gactccatct
    16981 ttggcatata tcactgtata tccatctggt atggtatgtc cgttgaaatt cgcagtggcc
    17041 gcaacagtac taaatgtctg gcttctacct gtttctgaat aagctttctc ccctgctgct
    17101 tttgctgctg tgatttcttt ttctgtcgga tcaatcagtt gagtcgagga tgtggttgag
    17161 gttgtctcgt tgttgctaga ctgattggtg ctttctatgg actgtatttc agaatagggt
    17221 ggactatttg tctcctctgt cgtttggtta gcaaaatttg acgtttctgt ataaacgttt
    17281 acataaatac ttgataagct ccctaagaaa gtaaaaatca agatgatcga aatcataatg
    17341 ggatgtaagt attttctttt agatacagct ttgagtctag aaacaaaatg tttttgacat
    17401 atacgttgga ttttattttg agttttctta atcattttca tccctcctct caataaaaaa
    17461 tcatcaaata atcctttaca cgttattcta aatttaattt ttattatttt attgatgtat
    17521 agaaagtttg gggctttttt tctcttttta ttctaaggtt attttagtct tgtcctttaa
    17581 tacaaagatt ttatttttaa ataaaaaata ctcttttttt acgattattg aaaaa
//
LOCUS       DARBDN010000052        17150 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000052 DARBDN010000000
VERSION     DARBDN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.052"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            138..1475
                     /locus_tag="SCH06_001736"
     CDS             138..1475
                     /locus_tag="SCH06_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEG1078299.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            1523..3652
                     /locus_tag="SCH06_001737"
     CDS             1523..3652
                     /locus_tag="SCH06_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HEG1078300.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3627..4316
                     /locus_tag="SCH06_001738"
     CDS             3627..4316
                     /locus_tag="SCH06_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078301.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(4724..5410)
                     /locus_tag="SCH06_001739"
                     /pseudo
     CDS             complement(4724..5410)
                     /locus_tag="SCH06_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(5546..5740)
                     /locus_tag="SCH06_001740"
     CDS             complement(5546..5740)
                     /locus_tag="SCH06_001740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078302.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5790..6230)
                     /locus_tag="SCH06_001741"
     CDS             complement(5790..6230)
                     /locus_tag="SCH06_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HEG1078303.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(6234..7079)
                     /locus_tag="SCH06_001742"
     CDS             complement(6234..7079)
                     /locus_tag="SCH06_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEG1078304.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            7228..8646
                     /gene="pepV"
                     /locus_tag="SCH06_001743"
     CDS             7228..8646
                     /gene="pepV"
                     /locus_tag="SCH06_001743"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEG1078305.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8703..9650)
                     /locus_tag="SCH06_001744"
     CDS             complement(8703..9650)
                     /locus_tag="SCH06_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEG1078306.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(9873..10223)
                     /locus_tag="SCH06_001745"
     CDS             complement(9873..10223)
                     /locus_tag="SCH06_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEG1078307.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            10423..11502
                     /gene="pepA"
                     /locus_tag="SCH06_001746"
     CDS             10423..11502
                     /gene="pepA"
                     /locus_tag="SCH06_001746"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEG1078308.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            11646..11966
                     /locus_tag="SCH06_001747"
     CDS             11646..11966
                     /locus_tag="SCH06_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEG1078309.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            11988..12452
                     /locus_tag="SCH06_001748"
     CDS             11988..12452
                     /locus_tag="SCH06_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEG1078310.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            12657..13262
                     /locus_tag="SCH06_001749"
     CDS             12657..13262
                     /locus_tag="SCH06_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HEG1078311.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(13301..14590)
                     /locus_tag="SCH06_001750"
     CDS             complement(13301..14590)
                     /locus_tag="SCH06_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEG1078312.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            15018..15497
                     /gene="rlmH"
                     /locus_tag="SCH06_001751"
     CDS             15018..15497
                     /gene="rlmH"
                     /locus_tag="SCH06_001751"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEG1078313.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15700..16250
                     /locus_tag="SCH06_001752"
                     /pseudo
     CDS             15700..16250
                     /locus_tag="SCH06_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            16321..>17150
                     /locus_tag="SCH06_001753"
     CDS             16321..>17150
                     /locus_tag="SCH06_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HEG1078314.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT         5459 a         3105 c         3467 g         5119 t
ORIGIN      
        1 cataattaag gttttttaat tgaaaactga acatttatgg tcacccttta atgaaagcgc
       61 taactacata agttagaatg agtttgactg atatattagt ttgcttatca gaaaaacaaa
      121 atggacggag gaataacatg agtgatatta ttattggtat tttgttagtt atctcattct
      181 ttttcatggt ctggtactgt gtaaaaggct acaacttgat ggtcggcttt gccatcatgg
      241 ctactgtatg gatgggatta gcgctagtcg gaaacacgtt ttcaccaaac ccggcgatgg
      301 aagggcaagg agtaattgat gtgttgacgc atatctatac gacggggcca gctgagtacg
      361 ccaaatcgat cttggtaaat gtcttctttg gtgccttttt cgggcgtgtt ctagtagata
      421 gcggaatcgc agctaccctg attcgaaagg tagttgaact tggaggggac aagccaagaa
      481 tcacgatgag cttactatgt attgtaaccg ctgttatatt catgtcgatg acaggaatcg
      541 gaccagtgat ttctattgca gttattgtgt tgccaatctt gatgtcatta ggtatttcag
      601 taccggttgc actgttctca tttatgggct cgattatggc tggaatcttt gctaatatcg
      661 tcaatttcaa acaatatcaa acgatttatg ctggtttcaa tccagcggct gaaagctata
      721 cttataatga ctatttccaa attggtatga ttgggatgat tgtaagctta gttgtggtac
      781 taacggtcgc taatatatca atgaacaaaa agaaacgcta tgcaatggca gcaaacgtac
      841 cagctgaagg tggcgacgca ccaatgatct catggttagc cgtattatta ccagttttag
      901 gggtcgttct tttagatctt ccaatcatct taggttttat tctagcaggt atctgggcat
      961 tgctgtttac tggaaaattg cgcggaggtt ataaagaaat ctgtcgtcag tttgcgaaat
     1021 tatttacaga tggcgcagta gatgttgcgc caatggttgg tttcttgatg accttagcga
     1081 tgttcaataa ttcagctgcg tatgcttctc cttatttttc agctattttt ggagattgga
     1141 taccgcaatc accattagtc ttggcaatcg tatttgctat attgacacca ctaggatttt
     1201 tccgcggtcc aatgaatcta gtcggttcag gctcagctat tttagctgtc gtattagctg
     1261 ttaatccaac gatgtcgcca gcctttttgt tcccgttatt tgcaatcaca acgattgctc
     1321 ctcagcattt agatattaca caatcttggg ttgcttgggg attaggttat acaaaagtaa
     1381 cttctcgaga atatatgaag aaatccatcc caactggttg gatcatcgga gcgatcttat
     1441 gcctgatcac gttcttattg tacgggaacg cctagtaaac aaaacgtcga taaaaacgat
     1501 tagatgaatg gaggaaaaga aaatgaaacg ttttgtgcga atgggaattg atgttggcgg
     1561 tacacatacg aaagcagtcg caatcgataa tgcgacgcac gaaatcatcg gaaaatcttc
     1621 agtgaaaaca acccacgatg atgtccgtgg agtagccgca ggtgtcgttc agtcttttca
     1681 aaattgtttg ctggaaaata atatcagtcc agaagatgtt gtgtttgttg cacattctac
     1741 cacacaagcg actaatgcac tgattgaagg agacgtagca aaagtcggcg taatcgggat
     1801 ggcaaaaggt ggattagaag gttttttagc aaaacgacaa actagattga acgatatcga
     1861 tttagggaat aagaaaaaaa tagagattgt caatgcattc ttacctgtca aacacttaaa
     1921 tgtagaccgt gtttcagaaa cgatttcttc tttagaaaga gaaagagcgg aggtcttggt
     1981 ttcttctatg gcatttggag tagataatgg ggaaccagaa cgagttgttt atgaagcagc
     2041 atcggtaaaa tcgatcccta caacgatggc ttctgacatc acaaaattat atggattgac
     2101 aagaagaact cggacagcag caatcaatgc atctatttta ccaaaaatgc tagatacggc
     2161 aacctctaca gaagattccg tacgagaagc aggggtcaat gtttctttga tgattatgcg
     2221 cggagacggc ggagtaatgg aaatcaatga aatgaaaaaa cgacctgttt taaccatgct
     2281 ttccggtcca gcagcatcag tcatgggctc tttgatgtac ttgagagcgt ctaatggtgt
     2341 ttattttgaa gtaggcggaa caacaaccaa tatcggggtc attaaaaatg gacgtccagc
     2401 aatcgattat tcaattgtag gtggccaccc aacatatatc tcttcattag atgttcgggt
     2461 tctaggtgtg gcaggcggtt cgatggtacg ggctaatcag tcaggaatca tcgatgtcgg
     2521 tccacgttct gcacatattg ccggtctaga ttatgcagta tttacggaga cagaaaaaat
     2581 caaaggtcct aaggttgaat ttttctctcc taaagaagga gaccctgctg attacgtcaa
     2641 ggtagtgatg gaagacggag aagaagtgac tattacaaat acatgtgcag ccaatgtcct
     2701 tggattagtg caagaagaac atttttctta tggaaatgtc ccatctgcac gaaaagccat
     2761 ccaagcatta gctgattatt gtcatacgac ggttgaagac atcgcagaac agatcatgga
     2821 aaaatcctat gctaagattg aaccggtgat tttagaattg gcagacaagt atcacttgga
     2881 gaaagatcag atttctcttg taggtgtagg gggcggcgct gcctcattga ttacttactt
     2941 tagtaataaa atgggtgtga aatattcgat tcctgaaaac gccgaagtga tttcttctat
     3001 tggtgtagca cttgcaatgg tccgagatgt tgtagaacgt atcatccctt cgccaagtaa
     3061 agaagatata cgatcgttga aaaatgaagc gatgaataaa gcgattgaat caggcgctac
     3121 accagaatcg atcgaagtcc acgtagaaat cgatccacag acttcaaaag taacggctat
     3181 cgctactggt tctacggaag tgaaagcaac cgatctaacc aaggagatca caacagaaga
     3241 agcactagag cttgctgcag aggatatgcg attaaataaa aatgaagttt gcttattgga
     3301 aaatacacct ttcttttatg tatgcggcga acagaatcgt tcaaaaaatg ctggaagtct
     3361 tcggatcatc gatcaaaaag gatttatcaa ggtccaacgt ggacatgctt catgtatgaa
     3421 aacaactgca gccaattata tgacagctgt cgaacaactt tgggaagata tggcagttta
     3481 tcaaactgaa ttgattgccc gaccagaatt ttatctctgc ttaggagcaa gagtctctga
     3541 ttttacagcg acggatctgg aacaactaca gcttttgatg gatctggaag tatctactat
     3601 ggaaccggag gaagaagtga tcgtcgttgc cggaaatatc aaacaaacat aagttagaag
     3661 agttactaaa cgaattacaa cagatccccg aagaaatttg gggattctac cagtttcggc
     3721 gagatttatt ttggaaaaag attcctttgt ccaagcagaa aattcttata caacaatcaa
     3781 tcgattgtgg tatcgaaacg gcatgtagca tcaaaaaaaa gtaccctttt gccgatgtag
     3841 gagaaatttg tgaacaaatg gctgttccaa tcgtttcctg tgaatcagag caaataaacg
     3901 aacgaatcac ttttgcaact tatgcagaag atgaagggat tcgattgatg acggagccgt
     3961 tagaaaaatt aaaatgttca ggactagctt cgatctctaa agaaacagcg caagctttga
     4021 ttattggaca tgaactattt caccacatcg aagcttctgt taagggaatt tatacgcaaa
     4081 gcgaaaaaat tgtgctgtgg cggttgcctt tttatacaca tcaatcaaac attcgtgcat
     4141 tgagcgagat agcagcgatg agtttttcaa aagagatgaa tcaaagcgat ttttcgcctt
     4201 atgtattaga ggcagtctta ctttggccat ataatgaaat tcgtagccaa gggatcttag
     4261 aagaaataaa aaaaatagaa aaaagatgta cggagtatga tttagattac aaataaagag
     4321 actgtgacaa aagtcgtgtc acagtccttt ttttccgaat aaacggtgtt ctcctgtcaa
     4381 ctcctcggtc acaagtcaaa atattcaaca aacatgagaa gctgtttttt gaaattgttc
     4441 cttgtgactc ggagatgaac ggcaggctca cgacctcttg gaaaacggtg ttcaaaagct
     4501 tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctattt ttacttggct
     4561 gttcttatta cttgatgcag ggcagctttt tcacaacctc tcaataaacg gtgtgcaatc
     4621 agctgaccct cggtattagc tcaaaaaaaa cggcaaaata tgaggaacta ttttgccgtt
     4681 tctttctcta atactcaggt caaaacgctg attccaaaac ctcttatttg atgggtctgt
     4741 cctgaatatc ttcaaaataa tcggggtaat tatgaatcac gtattcttgc tcctcgataa
     4801 tcatatgtaa atgcatcgtg caaagaaatc cgacttcatc aaagttatga tcaatcattg
     4861 attgaagcat tgtctgatgt tcatctaata ctcgacccca gtctaattct gaaatcgtca
     4921 aacgtaacca tctgaaacgg ttcaagtgcg tactataact ttctagccaa tcccaaattt
     4981 ctcgttttcc agcaatttca taacaagttc ggtgaaaatc agtatccaaa tcaaaaaaag
     5041 cttttttatt ttgagcgatt actgcctgat cggtttgttc tagtattttt tctagtttag
     5101 cttgatctta cttggtcatt ttcgcactgc attcttgcag gatcggtttt tccaactttt
     5161 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
     5221 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
     5281 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
     5341 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
     5401 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
     5461 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
     5521 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttggatc ggtttgacac
     5581 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
     5641 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
     5701 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
     5761 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
     5821 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
     5881 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
     5941 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
     6001 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
     6061 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
     6121 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
     6181 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
     6241 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
     6301 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
     6361 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
     6421 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
     6481 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
     6541 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
     6601 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
     6661 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
     6721 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
     6781 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
     6841 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
     6901 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
     6961 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
     7021 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
     7081 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
     7141 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
     7201 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
     7261 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
     7321 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
     7381 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
     7441 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
     7501 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
     7561 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
     7621 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
     7681 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
     7741 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
     7801 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
     7861 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
     7921 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
     7981 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
     8041 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
     8101 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
     8161 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
     8221 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
     8281 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
     8341 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
     8401 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
     8461 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
     8521 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
     8581 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
     8641 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
     8701 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
     8761 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
     8821 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
     8881 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
     8941 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
     9001 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
     9061 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
     9121 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
     9181 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
     9241 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
     9301 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
     9361 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
     9421 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
     9481 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
     9541 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
     9601 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
     9661 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
     9721 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
     9781 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
     9841 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
     9901 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
     9961 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    10021 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    10081 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    10141 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    10201 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    10261 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    10321 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    10381 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    10441 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    10501 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    10561 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    10621 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    10681 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    10741 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    10801 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    10861 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    10921 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    10981 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    11041 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    11101 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    11161 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    11221 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    11281 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    11341 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    11401 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    11461 ttggataaat caacagtaaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    11521 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    11581 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    11641 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    11701 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    11761 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    11821 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    11881 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    11941 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    12001 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    12061 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    12121 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    12181 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    12241 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    12301 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    12361 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    12421 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    12481 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    12541 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    12601 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    12661 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    12721 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    12781 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    12841 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    12901 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    12961 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    13021 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    13081 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    13141 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    13201 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    13261 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    13321 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    13381 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    13441 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    13501 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    13561 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    13621 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    13681 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    13741 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    13801 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    13861 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    13921 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    13981 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    14041 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    14101 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    14161 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    14221 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    14281 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    14341 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    14401 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    14461 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    14521 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    14581 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    14641 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    14701 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    14761 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    14821 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    14881 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    14941 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    15001 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    15061 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    15121 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    15181 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    15241 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    15301 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    15361 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    15421 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    15481 ctccatacca caaataatga tattttttaa gagaaaaaat tatccctatt ttaaataata
    15541 gcaataggta gtggtaggga gaaatttata aataactttt ttatttgctt tggtagccaa
    15601 gtaagttgca aaagaaaaat agatactgtt aaaaagataa tgtagacata gaaacaaata
    15661 cgtaaaattt tagttagaat aatggcaagg agaaaaaaca tgatagatga aaaaaagtgt
    15721 ttaaaaaatc tattagagga tatggatgat attgaagaaa actatctaaa tggactggga
    15781 aaacaaatat atttcagata cttaagctat ctaaaaatga aataagacat agtaattttt
    15841 tagctttttt gtttgctcca aatgaaaccc acaatttatc tgatgagttt tttaaaatgt
    15901 ttttgaaaag gtatatagat tctaatgatg ataccaaagc tgctatcaat tattttgatg
    15961 ctttacttaa tagctatgaa gatttaattg tttacagaga aaataagaat attgatattt
    16021 tattggtatc ggaaaaaaat aaaatagtgg tgtgcatcga aaataaaatt ctgtcttcgg
    16081 agtctggagg gcaacttaat aaataccaaa tatatataga acgcaattat tctaactata
    16141 aaaaaatttt tgttttttta actccagatg gaaatgaacc cacaaatcct agttggggca
    16201 taattactta caagaatatc gttgaagaga gtgtaaaata ttttgtgtaa atagaaaaaa
    16261 ggaagtccct tctgtagaat agagttacca caacacattc acagaaaaga ggacttccat
    16321 atgaacgatt ttactacaga aattatggaa atactaatca ataaaggtga tttggatgat
    16381 ttgtttcgtc gtcacctaga attggctatt aacgctttat tacaagctga attaacggta
    16441 tttcttgact atgaaaagta tgatagagct ggatttaatt caggtaattc ccgtaatggg
    16501 aattattcgc gctcttttaa aacagagtac ggtgaattga atttagtaat acctagagat
    16561 aggaatggag acttttctca acaaacttta cctgcttata aaagaaccaa tgactcttta
    16621 gaaaccacta ttattcagct agttcaaaaa ggaattacta tgtccgaaat ctctgatcta
    16681 atcgaaaaaa tgtatggtca ttattacaaa ccacaaacta tttcaaatat gagtaaaatt
    16741 gtgtctgaag atgtttcggc atttaaagaa agaactttag aagctaaata ctcagtcatt
    16801 tttatggatg ctactcatat tcccttaaaa agacaaaccg tatcaaaaga agctgtctat
    16861 atagtaattg gtatcaggtt ggatggaact aaagaggttc taggatttac tatagctcca
    16921 actgaatctg cttatgtttg gaaagagatt cttcaagatc taaaagaccg tggtttagaa
    16981 gaggttttgt tagtcgtaac agatggttta agtggtattg acgatagtat tcatagtgtt
    17041 tatccaaatg ctcaatttca acaatgttgt gtccatatat ctagaaatat cgctcataag
    17101 gttcgtgtta gtgatcgaca agaaatctgt agcgatttca aattagttta
//
LOCUS       DARBDN010000053        16527 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000053 DARBDN010000000
VERSION     DARBDN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.053"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(29..727)
                     /locus_tag="SCH06_001754"
     CDS             complement(29..727)
                     /locus_tag="SCH06_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEG1078315.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="SCH06_001755"
     CDS             complement(720..2072)
                     /locus_tag="SCH06_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEG1078316.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="SCH06_001756"
     CDS             complement(2295..3695)
                     /locus_tag="SCH06_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEG1078317.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="SCH06_001757"
     CDS             3856..4593
                     /locus_tag="SCH06_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEG1078318.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="SCH06_001758"
     CDS             4718..5197
                     /locus_tag="SCH06_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HEG1078319.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="SCH06_001759"
     CDS             5194..5961
                     /locus_tag="SCH06_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078320.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="SCH06_001760"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="SCH06_001760"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEG1078321.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="SCH06_001761"
     CDS             complement(6864..7466)
                     /locus_tag="SCH06_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1078322.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..8041
                     /locus_tag="SCH06_001762"
                     /pseudo
     CDS             7572..8041
                     /locus_tag="SCH06_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8147..8731
                     /locus_tag="SCH06_001763"
     CDS             8147..8731
                     /locus_tag="SCH06_001763"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEG1078323.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="SCH06_001764"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="SCH06_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEG1078324.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="SCH06_001765"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="SCH06_001765"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEG1078325.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="SCH06_001766"
     CDS             10632..10811
                     /locus_tag="SCH06_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078326.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="SCH06_001767"
     CDS             10833..11858
                     /locus_tag="SCH06_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEG1078327.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /locus_tag="SCH06_001768"
     CDS             12033..13277
                     /locus_tag="SCH06_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEG1078328.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="SCH06_001769"
     CDS             13430..14377
                     /locus_tag="SCH06_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078329.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="SCH06_001770"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="SCH06_001770"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEG1078330.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="SCH06_001771"
     CDS             complement(15279..15521)
                     /locus_tag="SCH06_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078331.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="SCH06_001772"
     tRNA            15642..15714
                     /locus_tag="SCH06_001772"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="SCH06_001773"
     CDS             complement(15833..16471)
                     /locus_tag="SCH06_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEG1078332.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT         5634 a         2949 c         3324 g         4620 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagtt
//
LOCUS       DARBDN010000054        16454 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000054 DARBDN010000000
VERSION     DARBDN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.054"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            135..2606
                     /locus_tag="SCH06_001774"
     CDS             135..2606
                     /locus_tag="SCH06_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEG1078333.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2709..4445)
                     /locus_tag="SCH06_001775"
     CDS             complement(2709..4445)
                     /locus_tag="SCH06_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEG1078334.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4442..5146)
                     /locus_tag="SCH06_001776"
     CDS             complement(4442..5146)
                     /locus_tag="SCH06_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078335.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5277..5780
                     /locus_tag="SCH06_001777"
     CDS             5277..5780
                     /locus_tag="SCH06_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HEG1078336.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5740..6078
                     /locus_tag="SCH06_001778"
     CDS             5740..6078
                     /locus_tag="SCH06_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEG1078337.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6099..7517
                     /gene="ffh"
                     /locus_tag="SCH06_001779"
     CDS             6099..7517
                     /gene="ffh"
                     /locus_tag="SCH06_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEG1078338.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7629..8207
                     /locus_tag="SCH06_001780"
     CDS             7629..8207
                     /locus_tag="SCH06_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEG1078339.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8211..8732
                     /locus_tag="SCH06_001781"
     CDS             8211..8732
                     /locus_tag="SCH06_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEG1078340.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8811..9365)
                     /locus_tag="SCH06_001782"
     CDS             complement(8811..9365)
                     /locus_tag="SCH06_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEG1078341.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9618..9893
                     /gene="rpsP"
                     /locus_tag="SCH06_001783"
     CDS             9618..9893
                     /gene="rpsP"
                     /locus_tag="SCH06_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEG1078342.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9905..10156
                     /locus_tag="SCH06_001784"
     CDS             9905..10156
                     /locus_tag="SCH06_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEG1078343.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10281..11072
                     /locus_tag="SCH06_001785"
     CDS             10281..11072
                     /locus_tag="SCH06_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078344.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11242..11763
                     /gene="rimM"
                     /locus_tag="SCH06_001786"
     CDS             11242..11763
                     /gene="rimM"
                     /locus_tag="SCH06_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEG1078345.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11753..12514
                     /gene="trmD"
                     /locus_tag="SCH06_001787"
     CDS             11753..12514
                     /gene="trmD"
                     /locus_tag="SCH06_001787"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEG1078346.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12650..12997
                     /gene="rplS"
                     /locus_tag="SCH06_001788"
     CDS             12650..12997
                     /gene="rplS"
                     /locus_tag="SCH06_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEG1078347.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13129..14265)
                     /locus_tag="SCH06_001789"
     CDS             complement(13129..14265)
                     /locus_tag="SCH06_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1078348.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPDLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKIPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVNFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPNGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(14381..15295)
                     /locus_tag="SCH06_001790"
     CDS             complement(14381..15295)
                     /locus_tag="SCH06_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HEG1078349.1"
                     /translation="MKKIVFGLLFLGLVLSGCSTSPNSASTKENTVSSTSEYETKKLT
                     SSDVHKIKVGDDLTQVYQTLGSPLRKWTNDFVYKELDNAITRDELIVSISKDAQGDYY
                     KEHSELIEHGNSAKDIKKLEMLQYTYSTDSDDETMLIWVSPKTEQVVYYNQRTFLDKD
                     GKSKDSSSTTTTTTTSSSEPQTASVAHSIGEAVPFTSENGNSINVTVQSVSKDYGDDF
                     YKPEGLFYAKVDFLVENTGTTPFDASSSYLEFYDSSDIKSDLASRDYFSETIQPGKSA
                     QGTAYFEVKNDGTTFEVFFADTSWKGSY"
     gene            complement(15386..15814)
                     /locus_tag="SCH06_001791"
     CDS             complement(15386..15814)
                     /locus_tag="SCH06_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEG1078350.1"
                     /translation="MEMDTINLVEELKRKYQSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKRIEELKNLYGLPESAYRFLI"
     gene            complement(15819..16193)
                     /locus_tag="SCH06_001792"
     CDS             complement(15819..16193)
                     /locus_tag="SCH06_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1078351.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
BASE COUNT         5308 a         2960 c         3227 g         4959 t
ORIGIN      
        1 cctttttttt tgctatatga caggaatgaa aggtgtttgc aagcttaatg tgaggaacac
       61 tttccatatc tgttctatac tggataggag aagtttggaa atatccagaa aacgaaatca
      121 atcgaggtag ccacatgaag aataaatgga taaatcgaag taaaaaaaag aaagtaacac
      181 aaagatcatc agataaagtc atccgtcttt ttccatcgta taaagaagga ttaacggcag
      241 atcaagtcaa ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat cccacattca
      301 aaacaaatca gcaaatcgta ttggaaaaca tatttacgta tttcaatttg atctttctta
      361 tcttagccat tttgctttgt ttagtagaat cctataagaa cttgactttt ttaccagtta
      421 tcatagccaa tacaggaatc gccatttttc aggaaattcg atccaaaaag atcttggacg
      481 aactaaatgt tttaaataca gcaaaagtca atgtcatacg agacgggata gaacaaacaa
      541 tagatataga agaccttgta atagatgaca ttgttatttt agagactgga tatcaaattc
      601 cagcagatgc agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta ttgacaggcg
      661 aagcagatga aataaccaaa gaaataggtg atccattaat gtccggcagt ttcattgttt
      721 ccggaaaagc ttacgcccga ttagacaaag ttggagcaga ttcgtatatt tcccagctga
      781 cagtcaaagc caagacaatg ggagaaggag aacagtcgga gatgattgct tctcttaatc
      841 aattgatcaa atggattggg atcatcatta ttcctatcgg tatcctgctt ttttctcaaa
      901 gttacttttt taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa gcagcattga
      961 tcggtatgat acctgaagga ctgtacttgc tgacgacgat tgcattagca ttaagtgcga
     1021 ctaaactagc aaagcaaaga gttcttttac acaatatgaa aagcattgag acattggcaa
     1081 gggtaaatgt cctttgtgta gataaaacag gaacgatcac agaaaataaa atgtctgttc
     1141 aaaaaatgat cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa ttggaagcat
     1201 gcattgctga ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa gctgttaaag
     1261 catattttac aaaaaccact gatcaatcct atcaccatgt tattcctttt tcttctgtcc
     1321 aaaaattcag cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg cccgaaatgg
     1381 ttttgcgcga tcaattgccg gaatatgcgg aagagtttgt ttctttcgct gaaaaaggct
     1441 atcgcgtgtt ggtctttggt gtgtacgatg ggattcttga agaaccagta ttgacagaag
     1501 cagtcacacc attaggctat attctgattg ctaatcctat cagaaaagaa gcaagagcca
     1561 catttgatta cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga gataatccgc
     1621 tcaccgtatc caatgtagct gtccaagcag ggatttcaca tgctgatcag tacgttgatg
     1681 catctaaatt atcagaagaa gaatatgaag cagctgtcga aaaatataca gtttttggac
     1741 gcgtcaagcc agaacaaaag aaaatcttcg ttcaattgat aaagcgtaac aatacagtag
     1801 ctatgacagg tgatggcgtg aatgatattc tagccatgaa agaagcagac tgcagtatag
     1861 cgatggcttc cggaaatgaa gccgccatgc aggcctcaca agtggtctta cttgattctg
     1921 acttttcacg catgccagaa gttgttgcag aaggacggcg cgttgtgaac aatattgagc
     1981 gatcagccag cttgttttta gtgaagaata ttttctcctt tttgctctca ctgttttcag
     2041 tgatctttgc tctgacctat cctttagaac catcacaaat cacattgatt agtttgttta
     2101 ctatcggact tccatctttc ttgcttgctc tagaagaaaa caaaaagcga atcagaggga
     2161 aattcatcat gaatgtgatg gaaaaagctg tgccaggtgg actaacagat atgatcgtag
     2221 tcggtgcgtt ggtgatctgc ggggtgactt tgaatctaaa taaaacagat gtttctacag
     2281 catctaccat gcttttgatt gcagtagggt tcctcgttct ctataaaatc tgttcaccgc
     2341 tgaataaatt cagaagtcag atcattcttt tctgtgctag cggtaacttt ttttcggtca
     2401 tctttttgca taagctgttt tcaatcaccg gtatctcagc tgtatcactt ttgctgttga
     2461 gcattctatt tttctcggca gattcgattt ttaggcattt gaccacattg gtagaatatt
     2521 tgtttgaacg taaaaatgaa aaagagcaaa agccgtttag tcgcgtagct aaaaaatttc
     2581 tatcgatatt taaacgagaa aattgacgaa aagtatctca aaaaagagta aaaaagaaca
     2641 accactcgtg tatctttcga agcaggatga gtcatccaac tttaaaacgc acgagcagtt
     2701 gctctttttt acattttcgg aatggtaacg gtgaaagtcg aacctgttcc aagatgactg
     2761 tctacagtaa tcgtaccatt aaggagttgc acgtagtctt ttacaatcgc taaccctaat
     2821 ccggtcccgc ctgaatgtcg gcttcgcgcc ttgtctacgc ggtaaaaacg ctcaaagatc
     2881 cgttcctgat cctcaatgtc gatacctata ccaaagtctt ggacagaaaa cgatagatca
     2941 tctgttgcct gatagcggat aataatctcg ctgtcgcttt ttgaatattg gacagcattt
     3001 tcaattagat ttttgataat tggataaagg atatctgttt tagtagtaaa tggttcgttc
     3061 tttccaatca atcgaatcgt caaccgtttc ttttcgatga ttggctgata attttgaacg
     3121 atttgctgga aataaggttc tgtataaatt gtctggatct cgtaagaatt ctcgccatct
     3181 tttgacagct ggatgatttc ccgaatcagt ttatctaacc ggatcgcatc tttttgcatg
     3241 atctcaagaa aagaagtcag agtttgcggg tcatcttttg caccatccag taaagtctcg
     3301 gtaaaaccaa tcagtgaagt cacaggagtt tttaattcgt gagagacgtt gccaacgaaa
     3361 tccttttgta gcttttctaa acgtcgcact ttcgttaagt catacgccac ccctagaatc
     3421 tgtccggtac cttctgaatt agtaaagtag cgcaaactca agtctaatgt ctgccgacct
     3481 tctgtaaggg tgatctcctg atggatcagc ggatgctcag gagtcacttg atgaatcagc
     3541 tgaatgagtt ttggctcttg aatgacttct gtgtaccgct gttcaggttg atagcttacc
     3601 acgtttaaat gtagctgcat ctttggatta agcagtagta aacgagaatc agcatcatca
     3661 atcaggaata cgccaatcat cagttcgttc agtaacgtat ataattgctc ttctgtggta
     3721 gtacacgccc gatacatctt actcatttgt tcgctcaacg cattaatcgt ctgatacaat
     3781 tcttcccatt gatcgggtgt ttgcatgatt acttccgcct gattaggatt ttgcaccatt
     3841 ttttttagta cgggcagcac ggttttcaat ggctggtttt tttgatagat cagataatag
     3901 atcattcctg caagaacaag gaagaaagac agaaagaaga aaaagaccca acggcgaaaa
     3961 ctctcagttc tcggtaaaaa accgcttgtc ggttctgcga tacgtaaaat ggcttctaac
     4021 tggccacttt ttttgactgg taatgcgaca tataaaagat cctcattcaa agtagtactt
     4081 ttgcgcaaag cgctacctag gttcccacca ttcaatacgg ctttgatttc gggacgggag
     4141 tttcgctgtt cattcaatgt ttcattgttt gtgtcaaata agatctttcc agtagcatcc
     4201 attaaagtaa tccgttcgtt cgactgatgg acgaattctt ccaaagcagt tttgttttgc
     4261 gctgcttgga ggttttcgac atctaattgc cggatcagca gttgtgcttt ttttgtcagg
     4321 tagctttctt gctgttccac gatctgctgt tgaaaataat gggaaatcaa ttgccagcca
     4381 ccaaaaaaca aactaactaa aagaataaga aagaagagac gttcataaat ttttttccat
     4441 ttcatcgttt gggttcctga aacttatagc caaatcctct aatagtcacc aagtactttg
     4501 ggtgttttgg atctcgctcg attttttctc gcaaatgact aacgtgtaca tctacgattc
     4561 ggctttgtcc tgcgaagtca aaattccaaa tgcggtctag caatgtgtct cggtcgatca
     4621 cacggtcttt tcgtttcatg aaataaacaa gtaattcaaa ttctttcggt gttagttcaa
     4681 tcagatggtc gtctacggtc acttgataat tggtcaaatc agcagtgatt tgtccaatcg
     4741 atagatattc aggctcagct tcatcttttg attgcttacg aggttcaatt cgtctgaata
     4801 ttgctttcat acgggctaat acttcgcgag gactaaatgg tttggtcaaa tagtcgtcag
     4861 cacctatttc taggccaatg atccgatcca cttggtcatc tttagccgtc agcatcaaaa
     4921 tcggtgtttc atttttttct tgacgcagcc gctgagtgat ctccatgcca tccatcgttg
     4981 gaagcatcac atctaaaatg atgaaatcaa atgattgttc taatgctaat tctaatcctt
     5041 cgcctccatc tgtggcactg gttaccttgt agccttcttt ttccaaattg aacgtcaaga
     5101 gcgttacaat agaaggttca tcatcaacaa ctagtatttt tttcattcaa atctccttta
     5161 aataggtttc attctgttta tattttagca tagaatcagt acaaagggct attttacaaa
     5221 agaaataaat ggtataatag gaaggcactt tgctgaatag aaaggaagag cagtcaatga
     5281 ttggaatcag tgcatgttta ggcggtctgg cctgtcgcta tgatggacag aaaaaagaag
     5341 taccagaatt gatggaacta gttgaaactg gagaagctgt catggtctgt ccagaagtga
     5401 tcggcggatt accaattcct agagatcccg ctgaaatcat tggtggaaat ggattcgatg
     5461 tgtggaaaga tcaagcaaaa gtatggacga caagcggcga agatgtaacg gaagcgtaca
     5521 aaaatggcgc gatcaaagcc tatcaaaaat tgcaggaaaa acacattgat ctagtcatca
     5581 tgaaggaaaa aagcccttca tgcggaaccc attcgattta tgacggaagt ttttccggaa
     5641 taaaaaaaaa tggtgccgga gtggctactg cttattttat tcagcaaaaa atgactgtgc
     5701 tctctgatga agaatggctg aaaactagag gtgagcagaa tggaaatcga aaagaccaat
     5761 cgaatgaacg cgctctttga attttattcg accttattga cagaaaaaca aatgaactac
     5821 atggaattat attatgcaga tgatttttca ttaggtgaga tcgcggaaga atacgaagta
     5881 agccgacaag cagtatatga caatatcaag cggacaagca agatcttgga ggattatgaa
     5941 aaaaaactcc atcttttttc taattatatt gttcgagaac aggtattgga aaatatgact
     6001 gcatatatta cagataagta cccggaagat aaaaaactac ttgaatatgt acagcaaatt
     6061 caagcaatcg aagaataaat aaaaggaatg aagaaaatat ggcatttgaa agcttaactg
     6121 aacgtctcca gcaggcgatg ggaaaaataa gaaaaaaagg aaaagtatca gaagctgacg
     6181 taaaagaaat gatgcgggaa atccgccttg ccttactaga agccgatgtt aacttgcaag
     6241 tagtcaaaga ttttactaag cgcgtacgcg aacgtgcggt aggggcagaa gtgctggaaa
     6301 gtttatcacc tgcacaacaa atcgtaaaaa tcgttgatga agaattgacg atcacacttg
     6361 gttctgaaac agcagagtta aataaatcac caaaaatacc aactgttatc atgatggctg
     6421 gtcttcaagg ggcaggtaaa acgaccttta ctggtaaatt agccaattat ttaaagaaaa
     6481 atgaaaatgc tcgtccgctc ctaatcgcag gggacgtata tcgaccagct gcgatcgacc
     6541 aattgaaagt attaggtcaa cagctagacg ttcctgtatt tgatatggga actgaagtca
     6601 gcccggtaga gatcgtccgt caagggatgg agttagcaaa agaaaagaaa aacgactatg
     6661 tattgatcga tacggcagga cgtctgcata tcgatgaaac attgatggat gagttgaaac
     6721 aaatcaaaga attgacgcaa ccaaatgaga ttttgcttgt tgtcgatgcc atgactggtc
     6781 aagatgccgt caacgtagct gatagcttca accagcaatt aggtattaca ggggtcgtca
     6841 tcactaaact tgatggggat actcgaggcg gggcagcact atcgatccgc tcagtgacag
     6901 gcgcaccaat caaattcatc ggttctggtg aaaaattgac tgacttagaa gtattccacc
     6961 cagatcgtat ggctagccgt atccttggta tgggggatat gctgacattg attgaaaaag
     7021 cgcagcaaga ctacgacgag aaaaaagcgg aagaacttgc acagaaaatg cgggaaaatt
     7081 cattcgattt caatgacttt attgaacagc ttgatcaagt gatgggtatg ggcccactgg
     7141 aagatctaat caaaatgatc ccaggaatga atcaagtccc tggaatcgaa aacgtcaagg
     7201 tagatccaaa agatgttgaa cgcaaaaaag cgatggttta ttctatgacg ccagcagaaa
     7261 gagcaaatcc tgatctgttg aacccaagcc gtcgtcgccg aattgctgcc ggttctggaa
     7321 acagtgttgt tgaagtgaat cgaatgatca aacaattcaa ggaatcaaga aaaatgatgc
     7381 agcaaatgtc caaaggggat atgaacatcc caggtatgga ccaaatgttt ggttcaggcg
     7441 tcaaaggaaa actaggcaaa atggcgatga atcgaatgat caagaaaaat aagaagaaaa
     7501 agaaaaaacg gaaataagat gaaaaaaaca gcttcggtac agactgaaaa tgtctactgc
     7561 cggagctttt ctatcagcaa tttttattct ttactaatac aattactcta aacgaagagg
     7621 tggcacagat gagatgtccg tggagtgaac aaacagaaag tatgcggcaa tatcatgata
     7681 ctgtctgggg tgttcctgaa tatgatgacc aaaagctgtt ccgaaaattg atgcttgata
     7741 ttaatcaagc cggattgagc tggcagacga ttttaaataa aagtgaagca ttcgatgaag
     7801 catatgatcg attcgatatc aaaaaagtcg caaattatgg agaaacaaaa atcagtgaac
     7861 taatggaaaa caaaggaatt attcgtaacc gaagaaaaat cgaagcagcc gtccaaaacg
     7921 ccaaagcagt cttgaaaatt caagaagaaa tcggcagttt ttcagagtat ctttggtcgt
     7981 tttctaatgg aaaaatcgtt gattcttctt atcattcaca agaagaagtc ccaacaacaa
     8041 gtcctctttc agatgaatta gcaaaagatc taaagaaaag aggatttaaa tttatcggaa
     8101 gcacaacaat ctatgctttt ttagaagctg tcgggatcat caatgatcac cttgacagtt
     8161 gtttccgcaa agaagaggtc gtacgtatcg gcagaaaggg cgaataaagc atgcgaaaaa
     8221 tcatatttta tggtgctata agtttagatg gctatttggc aacgaaaacg gatgatcttc
     8281 aatggctttt tgacactcca acaggtaagc aaactactta tgaagctttt tatgaaacaa
     8341 tcgatacgac catcatgggc agaaaaactt atcaggaagc aaaaaaatat ttggagaccg
     8401 aagcaattta tccagagaaa aagaatttcg ttttttccac ccacgcacaa ttacaattgc
     8461 cagatgctga ggtcgtaaac gaagatcctg ttgcttttct aaaaaatcta caaatgacag
     8521 aaggaaaaga tatctgggtt gtgggtggcg gtcgattgat caaaccgcta ttggaacatc
     8581 aaatgattga tgaatggtat atccagatta cccctgtatt attaggggac gggattcctt
     8641 tattccaaaa aggaacatat gaagcgcgtt ttgaaatgct agacacgaca cgattcggtg
     8701 aatttatcga attgcattat gtacgaaagt agaagtaaat aaaataaaaa aggcaactat
     8761 atgcagaaat gtcctgtaca tagttgcctt ttttattacc gttatgcttt ttactctgtt
     8821 aatttgttag aaaaatctag atacgcatct aaaatcgttt ggaagaaact taatgttcct
     8881 tcaacgatat taccattttc atcaattaga ttcgcaacgt ttccgatata tgcttccggt
     8941 tgctgcaagg ttggcacatt caaaaagaca agtgattggc gtagatggtg gtttgcgcca
     9001 aagccgccga tcccacctgg tgatgcagta acgactaaac ctggtttatg atcccaaaca
     9061 ctgtgtccat aaggtcttga gcctacatct aaagcatttt tcaatactgc tggcacagaa
     9121 cggttgtatt caggagtaac gaaaacgaca ccgtctagtc ccctcacttc ctcacgaaaa
     9181 cgagtccatt cagcaggagc ctgttctgga gtttcgagat cctcattgta aaatggcaga
     9241 tcatcgattt ttacaaatac actttcgtac ccttcaggaa gcaatttcgc aaaagcttct
     9301 gctacttttt tgttgtaaga atcttttctt aaactaccaa taaaaaatcc aatttttttt
     9361 gtcatacgat ttttcctcct tcaaactatc tataataatc ttacaaaaga taagtaactg
     9421 gagcaaataa aaacacttac tgacaaaagc tacatagaag atagattact tatttttaac
     9481 aaaaaagaag tctaaaatct tctattttct aaaaaaaatc gaatttaatc aagctgtaaa
     9541 gaaaaaaagc tttacagggt aaaaaaaaac tgttacacta catcttgtga ataaaacaat
     9601 ggaggtggaa ataaataatg gcagttaaaa tccgtttaaa acgtatgggt tctaaaaaga
     9661 gtccgtttta ccgtatcgtc gtagctgatt cacgttctcc tcgtgatgga cgtttcatcg
     9721 aaactgtagg tacttacaat cctttgaaag accctgcaga agtagtttta aaagaagact
     9781 tagttcttga ctggttatca aaaggtgcac aaccttctga cactgtacgt aacatccttt
     9841 caaaagaagg cgttatgcaa aaacaccacg aagctaaatt ctcaaagaaa taaggtgacc
     9901 ggatatgaaa gatttaagcg acttagtctt aacaatcgtt cgtccgctag tcacttatcc
     9961 tgatcaagtc aagttagacg tcgtagagtc gaaagacttt tacgagtaca atctaacagt
    10021 ggctcctgaa gatattggcc gtatcattgg aaaacaaggg cgtgttgcta aagcaatccg
    10081 cacaatcgtt tacggtgttc ggatcaatgc accgaaaaaa gtgcgtttga atatcatcga
    10141 tgataaggaa aagtaaataa acgtgctgta ctcgaatttt cgagtgcagc ttttttgttt
    10201 tttttattaa ttgaagaaat gattatttgg caaaacaagc aagaaagcgt atccttatag
    10261 gaggagggag tgaacagcca atgagaaaga aaatgttatt tattccattt gctctattgt
    10321 taagcgcttg tagttcggtt actcaagaat cagacaatac acatctatca agcagtatat
    10381 ctgaaactgt taccagtcca gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa
    10441 caatggctac ctcaaataat gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc
    10501 caaatgttcc catgcctcta gatgtaccag tctcttcagg ctatctcaat atcgcagcga
    10561 cacatacaaa gcaaggttat tctattttat attacagaac agatcgtccc ctcgggttga
    10621 atgctgacga attgaatcaa gaaacgccta ttgcaaccta tctatatcaa tatgggtttg
    10681 cttctagtca agaaacaatc caagttttgc agccatttga gatcgacaca aatggtcagc
    10741 aagtggactt aggttctcga atcacagggt atcagcaagg tgcagcaggt tcaagttttc
    10801 ttgaatggca agaaggaaac tggcgtattc gaatccgtgg gaataatata gaaggccaag
    10861 atcccttact attagctaaa gaaatcgtag cttatttgga agaaaacagt ctaccagcac
    10921 ctgaacaatt tggtaaaatt actgttgata tgggtgatac gacgaatcga gccgtagaag
    10981 taagctggca agaaccgaaa aatgcctata cgatcactca tcaagatcct atgtctgcgt
    11041 tgaagatggc agtttctatg aagaggttgt gaaatcagcg cgctgatctg agcccatcat
    11101 ttaactccaa gtcacaggaa gtaatcaaaa atagcacgcc gcatttttgc ataattttgg
    11161 cttaatacct taaaagaaaa ctagaattgc ctcttcacac atgctaaaat aaaacagaca
    11221 aaaaagaaat ggggatataa gttgactgaa tacttgaatg taggaaaaat cgtaaacaca
    11281 caaggtatca aaggcgaagt ccgtgttatc tcaacaacgg atttcccaga agaacgttac
    11341 aaaaaaggaa cggtgctaac actattccaa gacggaaaag cacctgtgga attaacagtc
    11401 aaaagtcatc gcaaacataa aaattttgac ttattgagtt ttgaaggaca tccttctatc
    11461 aatgatgtgg aaaaatatcg ggatggcata ttaaaagtgt caaaagacaa ctctgtagat
    11521 ctagctgaaa atgaattcta ttaccatgag atcatcggtc tgcatgtatt agaagatgga
    11581 actgagttag gtaaagtaaa agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt
    11641 caacgtccga aaaaagctga tatattgctt ccatatatcg cttctgtcgt caaagaagtc
    11701 gatttagaag ctggagtggt ccgtgtagaa attccagaag gactgattga cgatgaagat
    11761 tgatgtattg actttatttc caagaatgtt tgaaggtcct atgggggaat ccatcatcgg
    11821 taaggctgta gataaaggat tattagatat caatatctct aacttccgcg attattcaga
    11881 taacaaacat cagacagtag atgattatcc atacggcggt ggagcaggta tgctgctcaa
    11941 agtccagccc atctatgata acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa
    12001 aagagtaatt cttcttgacc cagctggtaa acgattcgat cagaaaatgg cagaagaatt
    12061 ttcacaagaa gaacacttag tattcatttg tggtcattat gagggatatg atgaacgtat
    12121 ccgcacatta gtgacagatg aagtttcctt aggagattat gtccttactg ggggagaatt
    12181 aggtgcgatg gtcatgatcg atgcaacagt tcggcttttg ccagatgtgt tagggaatca
    12241 gacttcagct caaacggatt cttattcaac cggtttattg gaacatcccc aatatactcg
    12301 cccggcagaa tataaaggga tgaaagtacc agaagtattg acaaatggaa atcataaatt
    12361 gattgaagaa tggcaattaa aagaatcact aagaaggacc tatcaacgtc ggcctgatct
    12421 tttggaaaca cttgaatgga cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga
    12481 agaacaagaa aaaacagcag atgaagccaa gtgacttttt ctaaaatctt ctttacagta
    12541 ggttgataat atgttagtat tttatggtga gtgcaaaagc acttaactat tacgatattc
    12601 cgctgtgaga aaagctcata agaatatttg gaataaggag aagaaaacca tgaatccatt
    12661 aatcgaagaa ttaacaaaag aacaattacg ttctgacatc ccagcgttcc gccctggtga
    12721 cactgtgcgt gttcacgcaa aagttgttga aggtactcgt gaacgtatcc agttatttga
    12781 aggtgttgtt atcaaacgcc gcggtgctgg aatcagcgaa acttatacag tacgtaaagt
    12841 ttctaacgga gtgggcgttg aacgtacatt cccattgcat acaccacgtg ttgcaaaaat
    12901 cgaagtagtt cgctacggta aagtacgtcg tgcaaaattg tactacctac gtgcattaca
    12961 cggaaaagct gctcgtatca aagaaatccg tcgttaatca tcgttatcag actgagaaag
    13021 aacccttggt attcaagggt tctttttttg ttctctgttt ttttatatta acgatttcta
    13081 tttgggacat ttttgattaa taaaaagggg caaaaaaggg gcaacaagtt acagtttttc
    13141 tatatcttct ttcaattttt cttttactcc ctttgtcaca tgcaaataaa tcttttcagt
    13201 gatatcacta ttttcgtgcc caacgcgatc ctgaatagca tacagaggag ttcctagttc
    13261 cgctaatttt gaaatatggg tatgtctaaa aatatgtgaa ctaagttttt tatcaatctt
    13321 catgtcagct ttatgatttc tcaaataggt gttaattgct gttagttgga aaggagttcc
    13381 tttcgttgtt tgaaatagaa attgaccatt cggatttaat tctagaagct cattgtaaat
    13441 agctatcgct ttttttggta aatcaatttc tcgcattcca gcagcagttt ttgtagaatc
    13501 agattttttc atatcagcta ttgaacgttc tctatacatc atcgtcccat ttataactac
    13561 tgatgcatta ttattggtaa tgtgtacatc gtctttactt aatgcgattg cttctccagg
    13621 cctcattcca gtcaaatata gccactggaa aaggagagaa tatcttttat tgtgtgaagt
    13681 tgtgaaattt actagtcttt tatattcatc atcttctaaa aacttatctt taatttttat
    13741 cgtttttgac tctcgtttat aatcaataac tacttcgttg ataggatttt tttctacata
    13801 gccttttttc atagcgtatg aaaaaagaag attcaatttg gatttaatta cactgacgta
    13861 cttatttgac aagtcatctt tatatatcat atcttcaaaa atattattta aatctactgt
    13921 attaatacca gaaacgatgt aagtctcagg tatctttttc tttatagtgt ttaagatatt
    13981 attcgtagga taatatgtag actccttaac ttgtcttttg taaataacta accattcttc
    14041 gacaagctca tgaaatgtta gatcaggctt ctgaagtgtt ttttcgttta attttatatc
    14101 aattttttta tttaactcta gcaatgccac tttctgagtt tctcgagatt tatttttata
    14161 agtaatgctc actttttttc tttttctagt ttttggatca atatatcgct cattatattt
    14221 atatactttt tttccgtttt tatcagtttt ggtttcaatc cacattgttt tcatctccta
    14281 tttgttgcta taataggaat ggataagtaa gccaattata gcaggtttat ttttcatcac
    14341 gtccacaaac tttggcgagg gagggggcgt gtttttttgt ttagtagcta cctttccatg
    14401 aagtatctgc gaagaacact tcaaatgttg ttccatcatt tttcacttca aaatatgctg
    14461 ttccttgtgc ggatttaccc ggttggatgg tttccgaaaa gtaatctcta ctagctaaat
    14521 cagatttaat atctgatgaa tcataaaatt ctaaataact tgaacttgca tcaaaaggtg
    14581 tagtccctgt gttttctaca agaaaatcta cctttgcgta aaataggcct tctggtttat
    14641 agaaatcatc accgtaatct tttgatacag actggacagt tacgttaata gagttaccat
    14701 tttcagaagt aaaaggaact gcttctccta tactatgtgc aactgatgcc gtctggggtt
    14761 ctgaagacga agttgtagtt gtagttgtag tagagcttga atctttggat tttccatctt
    14821 tatctaagaa agttcgttga ttataatata caacctgttc agtttttgga ctaacccaaa
    14881 ttaacattgt ttcatcatca gaatcagttg aataagtata ttggagcatc tctaattttt
    14941 ttatatcttt tgcactattt ccatgttcaa ttaattcaga gtgctcttta taataatctc
    15001 cttgtgcatc ctttgaaata gatacaatta attcatcccg tgtgatagca ttgtctaatt
    15061 ctttgtaaac aaaatcattt gtccatttac gtaacggtga accaagtgtc tgataaactt
    15121 gagttaaatc atcaccaact tttattttat gaacgtctga tgaagttagt ttttttgttt
    15181 catattcaga tgttgatgaa acagtatttt ctttagtgct agcagaatta ggactagtgg
    15241 agcatccgct taataccaag cctaaaaaaa gcaacccaaa aacaattttt ttcattttta
    15301 attcctcact tctatgatat gatttttttg taggatctta gaaataaggt ttttagtccg
    15361 tgttgcagca cggacttttt ttacattata taagaaagcg ataagcgctt tctggaagtc
    15421 cgtaaagatt ctttaattcc tcaattcgtt taggatattg atcattgtct tctttgtata
    15481 gagaaacaat gagattagca gcaaagcaat tagcttcgct ttcagatttg cttctagatg
    15541 ttcttgttga tacatagtaa ctggataagc cacgatgaaa aatagcgtga cctaattcgt
    15601 gagcgcaaat gtagaatctt tcctcagagt ctctcagttc atcatttaag aagattattg
    15661 cacgacctct aatttcttga aactgtcctt tgggattctc gataaaagga acgtattgaa
    15721 ttttaatgcc catcttttca caaatataaa aaggattagc ggactggtat ttccgcttca
    15781 actcctcgac taaattaatc gtatccatct ccataagctc acatcttttt gcctttttct
    15841 ttgtcttctt tcacaatatc ccagaaggtt ccaataagga tatcttttac gcgttggacc
    15901 tgttcaggcg tcagtgtttc tccgccataa gacatattga catttgaatc tagtaattta
    15961 tcaagttcaa ctacttcatc ttttgttgcc cagtcaggaa cttggtttct accgagtaaa
    16021 taatcagtag ttacattaaa ataatctgct acaagttgta gtcttttagt actaggagtt
    16081 ctatttttcc attgataaat cgtgttttta ggtatattta attcttcttc caattgagtt
    16141 atacttatgc ctcttttatg agctaattcc tttattctat ctagtaaatt cattttcgca
    16201 cctcacaagc tacgaaaaca ctaataaaaa aattagttaa aggtgttgac aactaataaa
    16261 agtgttagta tactgttttc gtaagctaaa atattagcta aaaagacttg ataactaata
    16321 aacacttcac ggtcggcaaa ctctgaaatg taaattacta ggcatttctg tgtcttattt
    16381 agctatgtct atatactaat aaaaatatta gttattgtca acgaatatta gctaattttt
    16441 tagcttacag atta
//
LOCUS       DARBDN010000055        16384 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000055 DARBDN010000000
VERSION     DARBDN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.055"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(152..550)
                     /locus_tag="SCH06_001793"
     CDS             complement(152..550)
                     /locus_tag="SCH06_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HEG1078352.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(547..1320)
                     /locus_tag="SCH06_001794"
     CDS             complement(547..1320)
                     /locus_tag="SCH06_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEG1078353.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1317..2000)
                     /locus_tag="SCH06_001795"
     CDS             complement(1317..2000)
                     /locus_tag="SCH06_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEG1078354.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2167..3054)
                     /locus_tag="SCH06_001796"
     CDS             complement(2167..3054)
                     /locus_tag="SCH06_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1078355.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3051..3920)
                     /locus_tag="SCH06_001797"
     CDS             complement(3051..3920)
                     /locus_tag="SCH06_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1078356.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4057..5343)
                     /locus_tag="SCH06_001798"
     CDS             complement(4057..5343)
                     /locus_tag="SCH06_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1078357.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5616..6194
                     /locus_tag="SCH06_001799"
     CDS             5616..6194
                     /locus_tag="SCH06_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEG1078358.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPMKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6194..7123
                     /locus_tag="SCH06_001800"
     CDS             6194..7123
                     /locus_tag="SCH06_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1078359.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7120..8856
                     /locus_tag="SCH06_001801"
     CDS             7120..8856
                     /locus_tag="SCH06_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEG1078360.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="SCH06_001802"
     CDS             complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="SCH06_001802"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEG1078361.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9752..10261)
                     /locus_tag="SCH06_001803"
     CDS             complement(9752..10261)
                     /locus_tag="SCH06_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEG1078362.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="SCH06_001804"
     CDS             complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="SCH06_001804"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEG1078363.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11562..12653)
                     /locus_tag="SCH06_001805"
     CDS             complement(11562..12653)
                     /locus_tag="SCH06_001805"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEG1078364.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="SCH06_001806"
     CDS             complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="SCH06_001806"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEG1078365.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="SCH06_001807"
     CDS             complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="SCH06_001807"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEG1078366.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="SCH06_001808"
     CDS             complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="SCH06_001808"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEG1078367.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4729 a         3621 c         2913 g         5121 t
ORIGIN      
        1 gcatattttg aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc
       61 ataagtattc acgagaaaaa tgcaaacaaa aaagcggaaa taacgctcat ccgccttctt
      121 gtttgtgttt atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat
      181 tttcatctaa aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac
      241 caatgacttt gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga
      301 tgccttgacc aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca
      361 caatatcttt ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag
      421 aacctcttcc atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa
      481 catcttcgcc cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa
      541 gatctttcat ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc
      601 atcttttcgt ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat
      661 cattgcaacc acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat
      721 tgccacgctc attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt
      781 atcaaaagcc attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc
      841 gtatcctggg atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa
      901 tcctactgct gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct
      961 cccctcgctc aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc
     1021 tactaagaac cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc
     1081 aatagcactg cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa
     1141 aaggatcaac ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt
     1201 gcgcatacga aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc
     1261 caaaatgact tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat
     1321 tggaagatca cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc
     1381 attccaaaac tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca
     1441 agggccaaga taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca
     1501 atcggcataa attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata
     1561 gccatcaatt gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat
     1621 actccagtgc cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat
     1681 atatcatata cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc
     1741 ccgatagcaa atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc
     1801 cctactagat ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt
     1861 ccgatcatca tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt
     1921 gcaaaaacaa acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact
     1981 tctttaaaat tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga
     2041 aagagttttc gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac
     2101 acacgtccca aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt
     2161 gtttttttat tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa
     2221 tacgatggca gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg
     2281 tgtataggaa gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg
     2341 caaagctact aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc
     2401 cgcggcatag gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt
     2461 tagaccgtct aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg
     2521 aaagaagaag atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt
     2581 gattcccaaa accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc
     2641 cgcaaaagga accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact
     2701 ttgataaatc tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt
     2761 caccaaagcg atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa
     2821 caaattttga aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc
     2881 cacgggtgta ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga
     2941 taggatgctt aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc
     3001 ttgttttttg acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt
     3061 tctcctccta ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag
     3121 gaaactgctg ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat
     3181 tgagataggg tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca
     3241 aaaagctgca atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa
     3301 tttgggatcg tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct
     3361 tcataaatct ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca
     3421 gtccaacgcc aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac
     3481 cagccaatcg gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat
     3541 tgagaaaata gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga
     3601 aagatagcgg ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa
     3661 ataaaaagtg ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta
     3721 aaaaaagctt ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta
     3781 aatgtcatat tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga
     3841 ataaaaacca tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg
     3901 aataaatctt tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa
     3961 agacaagaaa gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg
     4021 atgaaaaagc gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac
     4081 ttgtttttgt gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag
     4141 agcttcagct acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat
     4201 ttcagatgtc catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc
     4261 ttcttgataa gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt
     4321 cgcaagagtg cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc
     4381 tgaatcttct ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc
     4441 ttgcgctttt tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga
     4501 ttggttttct gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac
     4561 tgctcctgat tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc
     4621 ttctttcaaa agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat
     4681 cgtgactgtc tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct
     4741 tactcgacca aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac
     4801 atctcgcgct acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata
     4861 acctgcttct gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg
     4921 aacaccgtat attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc
     4981 ttcctttaca atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg
     5041 tatcctataa tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa
     5101 agcggtgttc agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt
     5161 ttcttcgttc tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc
     5221 ccacgcccag acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc
     5281 tgttaagaaa cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt
     5341 catttttatc cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc
     5401 aaaatttgaa aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata
     5461 aaaaaataca aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa
     5521 atggtgaggt ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt
     5581 taaattacaa gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg
     5641 atgatgaaca gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt
     5701 ttcaattaat agggactttt tccagtccga tgaaagcgct tgatttttct ttggtacatg
     5761 caatcgatat cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc
     5821 ggctattaaa acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat
     5881 ttgatatggt taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat
     5941 tgagtcctga tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc
     6001 ccaacaaaag cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga
     6061 ttgctggaca aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct
     6121 gttatatacc gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat
     6181 cacccattca ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc
     6241 ggaagaatcc ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca
     6301 aaagtttcgt caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat
     6361 ccaagatatc aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta
     6421 tcataaggga aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga
     6481 gcagcaagca agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa
     6541 agaacttgag aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa
     6601 acatgaggca atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg
     6661 gaatgaagaa ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta
     6721 tttcgaagat ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc
     6781 aaatgcaaaa aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa
     6841 ttatgagaaa gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta
     6901 tctctcagcc atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt
     6961 ccgtatcagt aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg
     7021 tgagaaagtc ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg
     7081 aatgacacct tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag
     7141 catgaactct ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc
     7201 gtcatttctt tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa
     7261 tcgaatgatg tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc
     7321 gagaatacat tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat
     7381 ccagcccaac atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct
     7441 ctttcaaaaa tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga
     7501 acttttgtcg gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg
     7561 attgctcaga gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga
     7621 ttgactcttc gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca
     7681 ttgaatcacg tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt
     7741 tttcaatctg tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg
     7801 atcatcgcat caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta
     7861 acagtaggtg aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc
     7921 caggattgta cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg
     7981 atttttccga ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt
     8041 atgtatttgg atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta
     8101 gaggaagatg gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta
     8161 gggaatacga tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa
     8221 gacgaaaaga agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat
     8281 tttatttata atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa
     8341 gcagttcaag gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa
     8401 gaagtgattc cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt
     8461 atgcgatatg gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta
     8521 tctatgccga atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac
     8581 aataaaacgc aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc
     8641 gaagtgattg ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat
     8701 ttttcaggaa tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca
     8761 tatggcttaa cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg
     8821 cttcttccta aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt
     8881 tattttaagt taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact
     8941 gtcagcactg gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg
     9001 agcgcattct ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat
     9061 tctcccaagc tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag
     9121 ccaaaagctg ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg
     9181 acactcattt ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa
     9241 aaacgtgtct ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca
     9301 tgctgtgctg tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca
     9361 tacattgctg cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt
     9421 tctaaaaact gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt
     9481 gttgctggat tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg
     9541 acttctggat gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc
     9601 tctacaggaa cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg
     9661 atggaagcat acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg
     9721 aatgaacttt ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg
     9781 tatcgatgat cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt
     9841 cataccaaga aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag
     9901 ctaaaggtcg aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg
     9961 cctctaagta aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga
    10021 caatccctcc accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg
    10081 actccacttt tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt
    10141 ggatatgttc ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta
    10201 accctttacc gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca
    10261 tgagcttctc ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt
    10321 gaaacagctt cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc
    10381 agcatcatac cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc
    10441 ggcccatgga tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat
    10501 tcttctgcca ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg
    10561 atgatcgtga ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc
    10621 agacgcggaa tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt
    10681 aaatcagccg attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc
    10741 tccaacacat ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt
    10801 tggctttccg gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct
    10861 ggaacagtta tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct
    10921 tccactgtga tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt
    10981 tctttttcaa cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat
    11041 ttgacttgcg cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct
    11101 gtcacagtga ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg
    11161 cgtaaaggtt ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga
    11221 gtagtcgtaa aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag
    11281 tttcccatgt caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc
    11341 ttgatcacct cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta
    11401 ctcagacaat cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct
    11461 ccaaacatga tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt
    11521 aatccatgta tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga
    11581 taactggtat tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa
    11641 ctgatttgca gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa
    11701 gaaactcccg cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc
    11761 acatcgataa ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg
    11821 tctcgacttt cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg
    11881 atccattctg ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc
    11941 tgcttattgc tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg
    12001 atatctcgaa agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt
    12061 tctgcctgat tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt
    12121 atacggtcat gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt
    12181 tcttgcagtt tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca
    12241 ttttcaaata gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga
    12301 tgtccaccga caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta
    12361 ctgctgacat ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga
    12421 taagctaagg ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct
    12481 gtttcaaaat cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt
    12541 tttgactgac tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt
    12601 gccatagaag caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt
    12661 gccccctttt tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc
    12721 aacaagcgaa tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac
    12781 attttccgca acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc
    12841 tttgtaaggt tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat
    12901 gggtttcatg accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc
    12961 gcctagatta ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat
    13021 cacttctgag cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa
    13081 ggcattgata ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac
    13141 gtagcttcct aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt
    13201 atctccattt ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc
    13261 aacaactcgt acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc
    13321 aggtatttct gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag
    13381 ttcttccaga attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc
    13441 agaggaccgt tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa
    13501 atccgcgtgt cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac
    13561 ttctgctaca gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt
    13621 gacaggtgaa ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt
    13681 ttcgatcttc atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt
    13741 gatttcttct tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc
    13801 tggtccatgg gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt
    13861 tgaatgtctc tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga
    13921 tattcaattg gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg
    13981 gatgacttag atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag
    14041 ctgtcgatcc agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc
    14101 caatagctac tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat
    14161 ggccaattgt atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt
    14221 ccactacttt tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa
    14281 gatctttttc gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg
    14341 ctgatttgat gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa
    14401 cctcaggatc aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt
    14461 tgtttgtatt gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag
    14521 tcggaatttg aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat
    14581 cacccaccat tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg
    14641 ctaaaaaatc gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta
    14701 cgattgaaag gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat
    14761 atagtggagc aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt
    14821 gaagccatga tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt
    14881 tatcaacatg tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc
    14941 gagtgtctga atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga
    15001 gtaagtcttt tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg
    15061 gatctctacg atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac
    15121 aagttcccaa attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt
    15181 tttcatcaat gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg
    15241 aatcccacgt tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc
    15301 attaagccat tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt
    15361 tttaccgaca gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat
    15421 atcgctgtac tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt
    15481 cattccaaat tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg
    15541 gaaagcatat ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc
    15601 ggctttggcc attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc
    15661 agccatcgtc acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt
    15721 gccaggatgg aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc
    15781 tactccttca tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc
    15841 aatcactact cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg
    15901 atcgacgact ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt
    15961 ttttcccgct ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg
    16021 tggttttaca ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc
    16081 tttcctactt atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct
    16141 acagtgaaca tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata
    16201 gatgaatttc tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca
    16261 aacctggttt gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt
    16321 aatacgtatt cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt
    16381 aaga
//
LOCUS       DARBDN010000056        16356 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000056 DARBDN010000000
VERSION     DARBDN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.056"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..258)
                     /locus_tag="SCH06_001809"
     CDS             complement(<1..258)
                     /locus_tag="SCH06_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078368.1"
                     /translation="MERQESIREVQEVPTEQAKETQEGRSFSYGKNFSFLRPSIQISV
                     FVLWRIHNNRYSVGSQLFYQEICHALSKKYSQNAYKEALAFL"
     gene            complement(274..924)
                     /locus_tag="SCH06_001810"
     CDS             complement(274..924)
                     /locus_tag="SCH06_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078369.1"
                     /translation="MKKRFIYVCVGGLFLFGVGSTFFLIHEKLQLTAKEEKLTVEINK
                     FQEEKKGQEDLVTSLKEQLQQVESEVTTLKKANEELKNNDSTEKGNIQTFQKTVTEAF
                     EVLFNYEPDSFQERKNNCAPYLSDKLMKQYFKEGVSYGDSNGVSSELEKCSVYLKSTQ
                     KATIQGLVVVSYRNKIGDSSWNNAMNIFDVTFDPASKKITFMQNLGSSFNQQLLEE"
     gene            complement(935..2107)
                     /locus_tag="SCH06_001811"
     CDS             complement(935..2107)
                     /locus_tag="SCH06_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEG1078370.1"
                     /translation="MKKKLLLWCGFGCLPTLLLCMFGFLFMILLISSGSEEEEIDCSP
                     TEIVASTISLTNQGMETNGLQIAKEVQKHIPNTTLEGLAGMLGNFQQESSMSPTAIER
                     PNDPLSGHGIAQWTAGRTTALKNFAKERNKEWSDLGVQVEFLIHELNTTEKASQVALQ
                     AKSVEEATEQWQVKFERAGIPMMGNRITFANQWYAKLGKNDSDPVASITLENGANAGS
                     KDLTDYCLETTGTSSSSDSNVLNVAKSLIGYFHYSQPQRAQFGSVENPDKNGYADCSS
                     FVWLVLTKAGYKTPANVGWFTGSMTSDARGSKQYLQEIPESEAKAGDIIIVNLGSGVG
                     NDGHTAVLAEDWHGLSTKVIEQGGMNTNGVGEGQVNLSFGYLLNGGDICFARPIKK"
     gene            complement(2126..2998)
                     /locus_tag="SCH06_001812"
     CDS             complement(2126..2998)
                     /locus_tag="SCH06_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1078371.1"
                     /translation="MKKMILGSLFSATVLLGMVGTSAYADTTSPGDPSVPPTEIIPPT
                     EETPEVPEEPVLPPTDGGEETPEIPEIPETPETPEIPPTEENPDTGGGTETPEVPENP
                     DTGGGEGTPEVPPVEENPGNGGNTETPEKPSNPGGNEGNTTPPTTPPTNNGGTNTTPP
                     VQDVVVKPDGSIGSQQTGGQNVQIETNNASELTHIPTPSTPIETASGEKIVSVVDGVA
                     YKESGNGLTPISDKVEQLPSGNIAVKGSDGKMKVLPKTGEEVSLVATALGGLLASGSG
                     FAFWRKRKATQKMN"
     gene            complement(3020..3940)
                     /locus_tag="SCH06_001813"
     CDS             complement(3020..3940)
                     /locus_tag="SCH06_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078372.1"
                     /translation="MMMIRFTEVDNMSLLTDKKIALDKAFIQLKRENEELLARAEIGW
                     CTLEIYTENHEIPVFEGSYDFPVEEFHLISLIEQSLTENGQLSEEAQTFIQTLNSELP
                     KFYQVKKDQKNERRPTKIKKEKKTPLSVETAFTQSNGSLQKKKMSFQWLLFGFIVVVS
                     CGLFIMQLSTQREIEQLTKKEHQLQERIAFAEELATKQPQIDTFSRYFITNYYSGEMA
                     EERYRKKLQSFLTEKVAKQISPQKEKVKSILSWEMKKEGKHWQIAYVITLETEKKTQE
                     TKKVSFQLEEQEKNYLVSTLPELDDFEINQ"
     gene            complement(3940..4209)
                     /locus_tag="SCH06_001814"
     CDS             complement(3940..4209)
                     /locus_tag="SCH06_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078373.1"
                     /translation="MIIVTGIVLLGIGVLFGYHFAYFPKIGEWQQRQAIQKYFQVKGN
                     EYTYYAEDEDSYIVSLNNQEYRVKFSLNNPIQVVYAVEVVEEVFD"
     gene            complement(4206..4586)
                     /locus_tag="SCH06_001815"
     CDS             complement(4206..4586)
                     /locus_tag="SCH06_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HEG1078374.1"
                     /translation="MITNYKKFWQNSFNYKGKATRKEYWLVALMNALIGFGLGLAIGL
                     AGALNASETIIGCLIGVLIVYCFVVLVPSLSLSVRRLRDAGFHWAFIFFYFVPTIGSL
                     VLLVLYCLPTKESIEDKQVQEETR"
     gene            complement(5053..6516)
                     /locus_tag="SCH06_001816"
     CDS             complement(5053..6516)
                     /locus_tag="SCH06_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEG1078375.1"
                     /translation="MKKTSKCLSALLLVGQVFGYTPAVLANEQGNNQLTNSQSATITE
                     ETTTNSTGEENQPETPTEDTIDTPDNPEMNAPPTGSEEQPETPNQPDKPEDNQQPEEE
                     PSEEPNEQPSDESSQTPQKPSTETEAEPPTKTERPQKAPEQSVTVPMNDVPQAQSIGS
                     EETKNYHQAPSAPIQELVPSSTQDNEGTIHFEKDASVETFIRKIGESARKIGQENDLY
                     ASVMIAQAILESASGQSQLAQAPNYNLFGIKGTHNGKGVSFATQEDLGNGTLYTTQAT
                     FRQYESYEESLKDYAKLLKEGLVGNTSFYDGVWKSKAKTYQEATKFLTGRYATDTSYD
                     KKLNGLIETYDLIKYDKEVAGPQLSKEGYMVPLKNYSISSSFGWRGEEFHRGLDMAAN
                     QGEPIYASKAGTVIEASYHTLSGNYVTIEHEDGSVALYAHQQEYCVNVGQTVEQGQII
                     GYVGSTGNSTGPHLHLELALDGSLTKDKLINPETVLF"
     gene            complement(6580..9597)
                     /locus_tag="SCH06_001817"
     CDS             complement(6580..9597)
                     /locus_tag="SCH06_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1078376.1"
                     /translation="MFKRMATWLAIFVTFLNPMLGSVTAFAETINESNSTEEVMKTEE
                     SKSSEEAISTETTSETTEETTTQDTTEDVSPPNVMTQEVPEGYEKYFITIEDIQKATS
                     FSEQERLAQESEEWQAILEKNAQTRATNLTLTENGRKDVNMTRITPEGTMYTHDYMVR
                     WQIDGEDVFCIQEGAITSAGIQYDVTPLENLITTSAIRKKISLIGYFGYYSSGSMDNY
                     VLAQTYIWEVLGGSFVNYGTIGQSNYEAFKQTVDRKINNLLEDPSFDSQTVTVKVGEE
                     VEVKDTKGVFSQWDGSVVENTANVQVRKSGNSLFIKANQNSNDGRISVSSLDPNSRGV
                     GSSFAYVDPVAQNLGKLYVPDPNRAGLTIKVLKNGDFKLTKLDAVTGKKVPNVTYEIK
                     RHDTGETKQYTTDAKGEIALKEIPAFYEKDGKYVQNKLDVKEVKAPAGYILDKQTHTI
                     TIEPNKEVTLTAKNDLQQFIPEGKKVKEVYNAEESWNQGKPVYDTVPAENIEFDIIAK
                     TDITAPDKETVLVKKGEVLDSVKTDKDGHWKANKKFYNGDQNKYQLIEKNVPDNYRQP
                     SEEQTTFSVAYGDNTTPVLTFELDVIDNLLKTGEVDFNKVDSINHLQLPGAKFLIEGM
                     TAHNKNVSFVYETKEEPEKLKLPDGTYKFTEIVFPEHYGQASGQTETILVTVKDGEVQ
                     PITVKNEEIVVPEEDQPEISTLFVTTTGGKDFNPKKDQELVDKVSQVFPKSAVGTEKY
                     WVTQFHKITADGKVTVLDTVKETRKVTDEKETFDVTFNYKADMVSDGDTIVATHIVYN
                     DKEEEEEFARHFDLTNKDQTVTAKEPKIETRFITVNGDQTFDPDKDQELIDHVSQEFP
                     ESTVGETKYWVTQFHKIDKNGKDTVVGTVETARKVSKASEEFKVSFDYKAGTLKDGEK
                     LVATHIVYKDKDHKEEEARHFDLKNEKQTLTAKGIKKETPTTPVKQTPTSTPKQSLPK
                     TGETVNDVLIALGLFLFVGVGAVLVRRKMKQSN"
     gene            complement(9748..10587)
                     /locus_tag="SCH06_001818"
     CDS             complement(9748..10587)
                     /locus_tag="SCH06_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1078377.1"
                     /translation="MKMLKVLALGIVVGGVSLAVGTNAEAAENKVWTPRSAEQIKAEI
                     KGNEYTIVWGDTLSAISQATNITVQKLADMNKITNVDLIYAGNKLVFNGNVASVQNSA
                     GETVAQTVIQEKDKVDPNQPVGQGTTSNTQTTPNTTTPTTPAGDQTGTTGGTTTPSTP
                     ENNGGTTQTPTQPGNGGNTGGETTPSNPSTGGGTTTPEEPSNPGGGDQGGNGGTTTPE
                     EPTIVVGEIGNSGKVFNTVDEAYDWANAEVSDPNSQWYNKGFMVDVIIYSDGSQKHTV
                     DFY"
     gene            10732..10977
                     /locus_tag="SCH06_001819"
     CDS             10732..10977
                     /locus_tag="SCH06_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078378.1"
                     /translation="MQLNNLNEIHDWAQNNLLNRKQAAKITGQNYDAFSSSLRRNNIK
                     PFLEIGDEPGPSIIRLYLREDIEKYAKQLEEKRQKRQ"
     gene            11040..11462
                     /locus_tag="SCH06_001820"
     CDS             11040..11462
                     /locus_tag="SCH06_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078379.1"
                     /translation="MNKKYIVSVGSIVLIVLAIIAFSVSNKTETQPQNTVQSTTTSQS
                     SDHSVYPSLNSLKETHGQDLIDLGSSQITTVLFEKKNIAFITPKEGTDLEFSIKVTNT
                     KENLFSIPDIQYTPNKLKIGDTFGLAKVNEQYFAYSLK"
     gene            complement(11556..11873)
                     /locus_tag="SCH06_001821"
     CDS             complement(11556..11873)
                     /locus_tag="SCH06_001821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078380.1"
                     /translation="MPVKGTSNFDFEIFYVDDEICGVFNKQKYTKEQAIEAWKNELFD
                     PEEEISFVVDESFVGWYHGNAEEEEVHYAGWWLEEGEPREQSVPVWVISENPLEEIEK
                     LEK"
     gene            complement(11900..12106)
                     /locus_tag="SCH06_001822"
     CDS             complement(11900..12106)
                     /locus_tag="SCH06_001822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078381.1"
                     /translation="MNWLKNEAELYVFHEEMQEKHLVPNVRNYLFWLEEKNDAQVFGK
                     SAQSPKIKLQLTSKQWNEHEWYIY"
     gene            complement(12087..12269)
                     /locus_tag="SCH06_001823"
     CDS             complement(12087..12269)
                     /locus_tag="SCH06_001823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078382.1"
                     /translation="MTKCERVSVTISFIALLLSVISLLNTAIFIGQVEKQKEISLSEW
                     RYEEVNEGMNNELVEK"
     gene            complement(12283..12633)
                     /locus_tag="SCH06_001824"
     CDS             complement(12283..12633)
                     /locus_tag="SCH06_001824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078383.1"
                     /translation="MKKSYKVFENNEIKEQEAIILSAQTPEEALEQALPFLVESQNIV
                     VEELPEFDSKIVFSFNCKKESEISVSPEFYCRSDISVEGLVMCASAFIEIFANHLQIS
                     VKELLDLLQEITNE"
     gene            complement(12659..12961)
                     /locus_tag="SCH06_001825"
     CDS             complement(12659..12961)
                     /locus_tag="SCH06_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078384.1"
                     /translation="MLSKQEKKYIRQKMYAMIGNRAITELSSEELLQVQQLAQIIGSN
                     SIFDSNPLPEMTLETLTAKRYKELRAIGYRMIDIRRALRISDTKFREWRTSNGLAN"
     gene            complement(12964..13197)
                     /locus_tag="SCH06_001826"
     CDS             complement(12964..13197)
                     /locus_tag="SCH06_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078385.1"
                     /translation="MTISVGNKVKYIGTAIPRYTNKLVVVKNILVNGLILEYPKEDRR
                     KVVVEGNGTWNMNSFICGFTEVEVTNDNENRSG"
     gene            complement(14183..14505)
                     /locus_tag="SCH06_001827"
                     /pseudo
     CDS             complement(14183..14505)
                     /locus_tag="SCH06_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14628..15743)
                     /locus_tag="SCH06_001828"
     CDS             complement(14628..15743)
                     /locus_tag="SCH06_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEG1078386.1"
                     /translation="MATKRFTATRKYNELYYQFPKVFITSEKYRSLSDKAKIAYMVFR
                     SRLDLAIQRNQVDSQGFVYFEFTEQELANALNCCRRSVNTIKKELKEYELLEIEDMGF
                     DQQTGKRNKARLYLGELDTTENDVYSLGPVDSTSVDSAQGKEEEESVDNLAIFDDFDE
                     KNPCENSAQLFNNSSNNLDTENLDTKIDTTSPVEMADDWQKEFIAHYSESTFVPKDVL
                     TWIVRSSAEWREAKEQLNMIYDSKRIIEKRQRKYNQTHGLSDGSEYRILGETFAEDLS
                     KTYQRCIQNEKIARHEGKAIQNRKGFYFRALLNFWECCVRELNLDPMATKLSDQAEYS
                     LLQAKRSCSYEDLETQIYGLSQLPKISMHNWLEELDT"
     gene            complement(15749..16147)
                     /locus_tag="SCH06_001829"
     CDS             complement(15749..16147)
                     /locus_tag="SCH06_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEG1078387.1"
                     /translation="MVKNKFRATDVLTQATFHMPKLFFIKSSKYYAMTAQAKYAYSLL
                     NEYLEESLIEKRIDEKKHVYISYTNQELAILLNVSEEEIEEIKNELEDYDLLTIEFGR
                     IYLKELIATMEDVRVYQHQNSFLIYGQDEV"
BASE COUNT         4332 a         3421 c         2564 g         6039 t
ORIGIN      
        1 caaaaaggca agtgcttctt tgtaggcatt ttgactgtat ttttttgata aagcatgaca
       61 aatttcttga taaaatagtt gactgcctac cgaataccga ttattgtgta tccgccacaa
      121 aacgaacaca ctgatttgaa tcgacgggcg taaaaaagaa aaattctttc cataagaaaa
      181 agaacgtcct tcttgggttt cttttgcttg ttctgttggt acttcttgta cctctcttat
      241 tgattcttgt ctctccataa ccttctcctt ttcttattct tctaaaagct gttgattaaa
      301 gctacttccc aaattttgca taaacgtgat tttctttgac gctggatcaa aggttacgtc
      361 aaaaatattc atggcattat tccaggaact atcaccaatt ttattgcgat acgacaccac
      421 aacgagccct tggatagtcg ctttttgtgt gctttttaaa taaacagaac atttctctaa
      481 ttcagaagac accccgtttg aatcaccata ggaaacgcct tctttgaaat attgcttcat
      541 cagtttgtca gaaagatatg gtgcacaatt gttttttcgt tcttgaaaag aatcaggctc
      601 ataattaaac agaacctcga acgcttctgt cactgttttt tgaaaggttt gaatgtttcc
      661 tttttctgtt gaatcattgt ttttcaattc ttcatttgct ttttttaacg tcgtgacctc
      721 gctttctact tgttgaagtt gttctttgag tgacgttaca aggtcttcct gtcctttctt
      781 ctcttcttgg aacttgttta tctccaccgt cagtttctct tcctttgctg ttagctgtag
      841 cttttcatga ataagaaaaa atgtactgcc tacaccaaat aagaacaatc cgcctacaca
      901 aacataaata aatcgtttct tcatttgaca cctcttattt ctttatcggt cgagcaaaac
      961 aaatatcacc accattaagc aaatacccaa aggataaatt gacttgccct tcacctacac
     1021 cgttagtatt cattccccct tgttcgatta ctttcgtaga aagtccatgc caatcttccg
     1081 ctaaaacagc tgtgtgtcca tcatttccca caccagaacc taagttcaca atgataatat
     1141 cgccagcttt tgcctcgctc tcaggtattt cttgtaagta ttgcttactt cctcttgcgt
     1201 cgctcgtcat tgagccggta aaccacccaa cgttcgcagg cgttttatac cctgctttcg
     1261 ttaaaacaag ccacacaaag ctcgaacaat cggcatagcc atttttatct ggattttcga
     1321 cactaccaaa ttgtgcccgt tgcggttgtg aataatgaaa ataaccaatc agactttttg
     1381 ctacgtttaa tacattacta tcggaagaac tgcttgttcc tgttgtttct agacaataat
     1441 cggtcaagtc tttacttcct gcgtttgccc cattttctaa tgtaattgaa gcgacgggat
     1501 cactgtcatt ctttcctagt tttgcgtacc attgattcgc aaaagtaata cgattcccca
     1561 tcattggtat ccctgcacgc tcaaatttca cttgccactg ttctgttgct tcctctacgc
     1621 tttttgcttg taatgcaact tgtgaagctt tttctgttgt gtttagttca tgaatcaaaa
     1681 actcaacttg tacacctaaa tctgaccact ctttgtttcg ctctttggca aaatttttca
     1741 aagcagtcgt tcgccctgcc gtccattgtg caatcccatg cccagataat ggatcgtttg
     1801 gtcgttcaat cgctgtggga ctcatactcg actcttgttg aaaattgcct aacatacccg
     1861 ctagaccctc taatgtcgta tttggaatat gtttttgtac ttcctttgca atttgaagcc
     1921 cgtttgtctc catgccttgg ttcgttaatg agatagtact tgcgacaatt tcggttggac
     1981 tacagtcgat ttcttcctct tcagaaccac tactaatcaa aagtatcata aacagaaaac
     2041 caaacataca tagtaatagt gtgggtagac aaccgaaccc acaccataaa agaagttttt
     2101 tcttcatgtt tgatccttca ttcgcttagt tcattttttg tgttgctttt cttttgcgcc
     2161 aaaaagcaaa accgcttcct gaagccaata atccaccaag tgctgtcgca acgagagaca
     2221 cttcttcgcc agtcttaggc aatactttca tttttccatc agaccctttc accgcaatat
     2281 ttccgcttgg aagttgttcg accttgtctg aaatgggcgt caagccattt cctgattctt
     2341 tataagcgac accatcaacg acggagacaa ttttttctcc tgaagctgtt tcaattggtg
     2401 tacttggtgt tggaatatgg gttaattcag acgcattatt ggtttcaatt tgaacatttt
     2461 gtccacctgt ttgttggctg ccaatacttc catctggttt tactacgacg tcctgtactg
     2521 gaggcgtagt gttcgtcccc ccattattgg taggtggtgt cgttggagga gtcgtatttc
     2581 cttcattgcc tcctggattc gacggctttt ctggtgtctc tgtattacca ccatttcctg
     2641 ggttttcctc aacgggtgga acttcaggtg ttccttcccc tccgccagta tctggatttt
     2701 ctggtacttc aggcgtttct gtgcctccac ctgtatctgg attttcttcc gttggtggaa
     2761 tctctggggt ttcaggagtt tctggtattt cgggaatttc tggggtttct tctcctccat
     2821 ctgttggtgg taaaacaggt tcttcaggaa cttcaggtgt ttcttccgtt ggtggaataa
     2881 tttctgtcgg tggtacactt ggatcacctg gtgacgtagt atctgcatac gcactggttc
     2941 ctaccatacc tagcaataca gttgcactaa ataaacttcc taaaatcatt tttttcatgt
     3001 gtttttcctc ttctcttatt tattgattta tttcaaaatc atctagttcg ggaagcgtgg
     3061 aaactagata atttttttcc tgttcttcca attgaaaaga cacttttttt gtttcttgtg
     3121 tctttttctc ggtttccaat gtaatgacat acgcaatttg ccaatgcttg ccttctttct
     3181 tcatttccca ggataaaata cttttgactt tttccttttg aggactgatt tgtttcgcaa
     3241 ctttttccgt tagaaacgat tgaagctttt tcctataccg ttcttctgcc atttcacccg
     3301 aataataatt cgtaataaaa taacgactaa atgtatcaat ttgtggttgt tttgtcgcaa
     3361 gttcttccgc aaatgcaatg cgttcttgta actggtgctc ctttttcgtt agttgttcaa
     3421 tctctctttg cgttgaaagt tgcataataa aaagaccaca agatacaacg acgataaatc
     3481 caaacaaaag ccattgaaaa gacatttttt tcttctgaag agagccgttg ctttgtgtaa
     3541 acgctgtttc tacagaaagt ggtgttttct tttccttttt gatttttgtt ggtcgacgtt
     3601 cgttcttttg gtctttcttt acttgataaa acttcggtaa ttcggaattt aaggtttgaa
     3661 taaaggtttg tgcttcttca cttaattgcc cattttctgt taaagattgt tcaatcaatg
     3721 aaatcaaatg aaactcttct actggaaaat catacgagcc ttcaaatact ggaatttcat
     3781 ggttttctgt gtagatttcc aaggtacacc agccaatttc cgctcgtgcc aatagctctt
     3841 cattttctct tttcaattga ataaatgcct tatctaatgc aattttttta tctgttagta
     3901 aagacatgtt atcaacttct gtaaatcgaa tcatcatcat tagtcaaaca cttcttccac
     3961 cacttctacc gcatacacca cttgaatagg gttatttaaa gaaaatttca cccgatattc
     4021 ttgattgttc aaactgacga tatagctatc ctcatcttca gcataatagg tatattcgtt
     4081 gcctttgact tgaaaatatt tttggatcgc ttgtctttgt tgccattcgc caatctttgg
     4141 aaaataggcg aaatgatagc caaataaaac gcctatccct aataaaacaa ttcctgttac
     4201 tataatcatc tggtttcctc ctgtacctgt ttatcttcta ttgactcttt tgtcggtaag
     4261 caataaagaa ccagtaacac aagagagcca atcgttggga caaaatagaa aaaaataaat
     4321 gcccaatgaa aacctgcgtc tcgtaaacgt cgaacgctga gagaaagaga cgggacaaga
     4381 actacgaaac aatacacaat caatacgcct atcaaacaac caattattgt ttcagaagca
     4441 ttcaacgctc ctgctagtcc aatcgctaag cctaggccaa acccaatgag ggcattcatt
     4501 aacgcaacga gccaatactc ttttcttgtg gctttccctt tgtaattaaa gctattctgc
     4561 caaaattttt tataatttgt gatcatatct ttgtcctttc taatgtttat ttttgattct
     4621 agtttcttct gttttactaa caatgaaact tgccataaaa aaggtggcca atacaccacc
     4681 agctagaaat ccacttacaa ataacaaaat tttttcctcc tttctaaaaa atttcgccat
     4741 aaaaaggcaa agtatgaaca cgataaatac catgtacata ctttgccttt ttatgcaata
     4801 tatgttaact ctccaagcaa ttactgattt ttaaattctt tataaataaa ataaaaatcg
     4861 tttgagtaaa gaaataagtc aatgaagacc caaacgataa aaaatattcc taatactata
     4921 tttaataaac tacgttctag atagatacga gatttcaaat taaaaaacga aaatgagaga
     4981 tacaaatata tcaaatattt aaaaagtaac cacattttct ataccactcc ttatcagaaa
     5041 cagccttatt ctttagaata agactgtttc tgggttgatt aatttgtctt ttgttaaact
     5101 accatctaag gcaagttcta aatgtaaatg tggtcctgta ctatttcctg ttgaacccac
     5161 ataaccaata atttgtcctt gttcaactgt ttgtcctacg ttcacgcaat attcctgttg
     5221 gtgcgcataa agagccacac ttccgtcttc atgctcaatt gtgacataat ttcctgacaa
     5281 agtatgatac gaagcttcta tgaccgttcc tgccttgctc gcatagattg gttctccttg
     5341 attggctgcc atgtctaatc ctctatgaaa ttcttctcct cgccaaccga aggaactaga
     5401 aattgaataa ttttttagag gtaccatata gccttctttg cttagttgtg gaccagctac
     5461 ttctttatca tatttgatta agtcataggt ttcgattaac ccatttaatt ttttatcgta
     5521 gctagtgtct gttgcgtatc ttcctgttaa aaatttagtc gcttcctgat aggtttttgc
     5581 cttacttttc caaacaccat cataaaaaga ggtatttcca actaagcctt cttttaacag
     5641 tttggcatag tcttttaagc tttcttcata gctctcatat tgccgaaaag ttgcttgggt
     5701 cgtataaagt gtcccattgc ctaaatcttc ttgtgtcgca aaagagacgc cctttccgtt
     5761 atgtgtgcct ttgattccaa atagattgta gtttggtgcc tgagccaatt gactttgtcc
     5821 gcttgcggat tctaaaatgg cttgcgcgat cataacagaa gcgtataaat cattttcttg
     5881 tccaatttta cgagcagatt caccgatttt acggataaac gtttctacag acgcgtcttt
     5941 ttcaaaatga atagtccctt cgttatcttg tgtgctggaa gggactaatt cttgtatcgg
     6001 tgcgcttggt gcttggtggt agttttttgt ctcttctgaa ccgattgatt gtgcctgcgg
     6061 tacgtcattc ataggtacag tcacactctg ttcaggtgcc ttttgtgggc gttccgtttt
     6121 tgttggcggt tccgcttctg tttcggtact tggtttttga ggagtctgtg agctttcatc
     6181 agaaggttgc tcatttggtt cttctgacgg ttcctcctca ggttgttgat tgtcttctgg
     6241 tttgtctggt tgattcggtg tttctggttg ttcttcagaa cctgttggtg gagcgttcat
     6301 ttctggatta tctggtgtat ctattgtatc ttcagtcggt gtttctggtt gattttcttc
     6361 tccagtggaa tttgttgtcg tttcttcagt gatcgttgca gattgcgaat ttgtcagttg
     6421 attgttgcct tgttcattag ccaaaaccgc tggcgtatac ccaaatactt gacctactaa
     6481 taacaaagca gataaacatt tactcgtttt tttcacaaga ttgcctccat tcttcaatca
     6541 atcatctaga gacagctgat tgctgtctct agtcatactt taattgcttt gtttcatttt
     6601 acgacgaacc agaacagccc ccacaccaac aaaaagaaac agtcccaatg caattaacac
     6661 atcgttcact gtttctcctg tttttggtaa gctttgtttt ggtgtgctcg tcggcgtttg
     6721 tttgacaggg gttgtcggcg tttctttttt aatgcctttt gctgtcaatg tttgtttttc
     6781 attcttcaaa tcaaagtgac gtgcttcttc ctctttatgg tctttatcct tatagacaat
     6841 atgagttgcg accaatttct ccccgtcttt taacgtgcct gctttgtagt caaaggatac
     6901 tttaaactct tcagacgctt tagaaacttt acgtgcagtt tctaccgtac caacgactgt
     6961 atcttttcca tttttatcaa tcttatggaa ttgagtcacc cagtatttgg tttcccctac
     7021 cgtagattct ggaaattctt gcgatacatg atcgatcaac tcttggtctt tgtctggatc
     7081 aaatgtttgg tcgccattca ctgtaataaa gcgtgtttcg atttttggtt ctttcgcagt
     7141 cactgtttga tctttattgg ttaaatcaaa atgacgagcg aattcttctt cctcttcttt
     7201 gtcgttatag acaatgtgcg ttgcgacaat cgtgtcaccg tctgaaacca tgtctgcttt
     7261 gtagttgaac gtcacatcaa atgtttcttt ttcatcggtc acttttcgtg tttcttttac
     7321 cgtatctaat acagtgactt ttccatcggc agtaatttta tggaattgcg tcacccaata
     7381 tttctctgtc ccaaccgcag atttagggaa tacttgggac actttatcca ctaattcttg
     7441 gtcttttttc gggttgaaat cttttccacc tgtcgttgtc acaaacaaag tagaaatttc
     7501 tggttggtct tcttctggaa ccacgatttc ttcgtttttc acagtaattg gttgtacttc
     7561 tccgtctttg accgttacta aaatcgtttc tgtttgtcct gacgcttgcc cataatgctc
     7621 agggaacaca atttccgtaa atttatacgt accgtctggt aattttagtt tttctggttc
     7681 ttcttttgtt tcatacacaa aggacacatt tttattatgt gcagtcatac cttcaatcag
     7741 gaatttcgct cctggtaatt gtagatgatt gattgaatcg actttattga agtctacttc
     7801 acccgttttt aacaagttgt caatcacatc taattcaaac gtaagcacag gcgtcgtgtt
     7861 atcgccatag gccacagaga acgtggtttg ttcttcagaa ggttgacggt agttgtctgg
     7921 cacatttttt tcaatcaatt ggtatttgtt ttgatcgcca ttgtagaatt ttttgtttgc
     7981 cttccagtgt ccgtctttgt cagtttttac tgaatccaag acttctcctt ttttcacaag
     8041 gactgtttct ttatctggcg cagtaatatc tgttttggcg ataatatcaa attcgatatt
     8101 ttctgcagga acggtatcat aaacaggttt gccttgattc caggattctt ccgcattata
     8161 gacttctttg actttctttc cttctggaat gaactgttgt aagtcatttt ttgcagttaa
     8221 cgtcacttct ttgtttggtt caatcgtaat cgtatgagtt tgtttgtcta gaatataccc
     8281 agctggtgct ttgacttctt tgacatccaa tttattttga acatattttc cgtctttttc
     8341 atagaatgca gggatttctt ttaaggcgat ttcccctttg gcatccgttg tatattgttt
     8401 tgtttctccc gtatcatgac gtttgatttc atacgtcaca tttggaactt ttttccctgt
     8461 gacagcgtct agtttggtta gtttgaagtc gccatttttt agaactttaa tagttagtcc
     8521 agctctatta ggatctggca cataaagctt tcctagattt tgagcaacag gatctacata
     8581 ggcaaaactt gaacctaccc ctctagaatt tggatccagt gaagaaacag aaattcgtcc
     8641 gtcatttgag ttttgatttg cttttataaa caaactattt cctgattttc ttacttgaac
     8701 gttagctgtg ttttcaacaa ccgacccatc ccattgagaa aacacacctt ttgtatcctt
     8761 aacttctact tcttccccta ctttaaccgt cactgtttgg ctatcaaaag aaggatcttc
     8821 aagtaaattg tttatttttc tatctacagt ctgtttgaaa gcttcataat tagattgtcc
     8881 aatagttcca taattaacaa atgaaccacc taaaacttcc caaatatatg tttgtgctaa
     8941 tacatagtta tccattgaac cactagaata gtagccaaaa taaccaatta aagaaatctt
     9001 ttttctaata gcacttgtcg taattaaatt ttcgagtggt gtcacatcat attgaatacc
     9061 cgcactcgtg attgcgcctt cttgaatgca aaaaacatct tctccgtcaa tttgccagcg
     9121 aaccatgtaa tcatgagtat acattgttcc ttcaggagta attcgagtca tattcacatc
     9181 tttacgacca ttttcagtca atgttagatt ggtagcacgt gtctgtgcat tcttttccaa
     9241 gattgcttgc cattcttcag attcttgcgc caatcgttct tgttcagaaa aagaagtcgc
     9301 tttttgaata tcttcaatgg ttataaagta tttctcataa ccttcaggga cctcttgagt
     9361 cattacattg ggcggagaaa catcttctgt cgtgtcctgc gtagttgtct cttctgttgt
     9421 ttcacttgtg gtttcagtac tgatcgcttc ttcactactt tttgattctt cagtcttcat
     9481 tacttcttca gtagaatttg attcatttat cgtttctgca aatgccgtta cagatcctaa
     9541 catgggattg agaaatgtaa cgaaaattgc caaccaagtt gccattcttt taaacatatt
     9601 tttttcgttc ctttcatttt atttttcagt cttctaaagt aatttcttat ggacttcgac
     9661 accgaaacat ttttatcctc ctcaaaacaa aaaaagacta gaacttataa ttctagtctt
     9721 catcaaccac ttacttttct tttattttta gtagaaatct acagtgtgtt tttgtgaccc
     9781 gtcactgtaa ataataacat ccaccataaa acctttgttg taccactgcg aatttggatc
     9841 gctaacctct gcattagccc aatcataggc ttcatctaca gtgttaaata cctttccact
     9901 attaccaatc tctccaacta caattgttgg ctcttcaggt gtcgttgtgc caccatttcc
     9961 gccttgatcg cctccaccag gattgcttgg ttcttcaggc gttgttgttc ctccacctgt
    10021 gcttgggtta gaaggagttg tttctcctcc agtatttcca ccattacctg gttgtgtagg
    10081 tgtttgagta gtgccaccat tgttttctgg tgtacttggc gttgttgtac caccagttgt
    10141 tcctgtttga tctccagctg gtgttgttgg tgtcgttgta tttggtgtcg tttgtgtatt
    10201 tgaagtcgtt ccttgtccta ctggttgatt cggatcaact ttgtctttct cttgaatcac
    10261 tgtttgagcc acagtttcac ctgcgctgtt ttgtacactt gctacattgc cattaaatac
    10321 taatttattt cctgcataga ttaaatccac atttgtaatc ttattcatgt ccgctaattt
    10381 ttggacagta atatttgttg cttgactgat tgcgcttagg gtatctcccc agacaattgt
    10441 gtattcattc cctttaattt ctgctttgat ttgttccgcc gaacgaggtg tccaaacttt
    10501 gttttctgct gcttcagcat tcgttcccac agcaagacta actcctccga ctacgattcc
    10561 tagtgccaat actttcaaca ttttcattgt ttttcgcctc cgatttgaat aaatttattt
    10621 acaaaaacat agtaccaaac ttatgtctat cagtcgatat attttttgta gattttttta
    10681 ttttttgata tactaacttt ggtactaaaa taactaaaag gaatgtcaca catgcaactt
    10741 aataatttaa atgaaataca tgattgggct caaaataatt tacttaatcg taaacaagct
    10801 gccaaaatca ctggacaaaa ctatgatgct ttttctagct ctttacgtag aaataatatc
    10861 aaaccatttc tagaaatagg cgacgaacct ggtccttcca tcattcgctt atatctaaga
    10921 gaagatattg aaaaatacgc aaaacagctc gaagaaaaaa gacagaaacg tcaatgaggc
    10981 gttttctgtc ttggatttac aagtaaaaca ataataaaca cttttacaac ggaggttcta
    11041 tgaataagaa atacattgtt tcagttggtt caatcgtact gattgtactc gctattattg
    11101 ctttttctgt atccaacaaa acagaaacac agccacaaaa tacggttcaa tcgactacta
    11161 caagtcaatc tagcgatcat tccgtctatc cttcactaaa tagtttaaaa gaaacgcatg
    11221 gacaagattt aattgatctt ggttcttctc aaattactac tgtcttattt gaaaagaaaa
    11281 atattgcgtt tattactcct aaagaaggaa ctgaccttga attttctatc aaagtaacaa
    11341 ataccaaaga aaatttattc tccattcctg acattcaata tacccctaac aagttaaaga
    11401 ttggggatac gtttggtttg gctaaagtaa atgaacaata ctttgcttac tcactgaaat
    11461 aagtttctaa tagcaagagg aaaaaccctc ttgttatttt tatcacataa tcattttata
    11521 aaaacgcttc gaaaatatca acatttttga agaaactatt tttctaattt ctcaatttct
    11581 tccaagggat tttcgctaat gacccataca ggcacagatt gctctcgagg ctccccttct
    11641 tctaaccacc aacctgcata atgaacttct tcctcctcag cattaccatg ataccaacca
    11701 acaaaggatt catctacaac gaatgaaatt tcttcttctg gatcaaataa ttcatttttc
    11761 catgcttcaa ttgcttgttc tttggtgtac ttttgtttgt taaatacacc acaaatttcg
    11821 tcatctacat aaaaaatttc aaaatcaaaa ttactcgttc cttttactgg catcttaact
    11881 tttcctcctt tgactcactt caatagatat accactcatg ttcattccat tgtttactag
    11941 ttaattggag ttttatctta gggctttgtg cactctttcc aaaaacttga gcgtcgtttt
    12001 tttcttctaa ccaaaaaagg taatttctta cattcggtac taaatgtttt tcctgcattt
    12061 cttcatgaaa aacatataat tctgcttcat ttttcaacca attcattatt cattccctca
    12121 ttcacttctt cataccgcca ttcagatagt gagatttctt tttgtttctc cacttgtcct
    12181 ataaaaatcg ctgtattcaa caagctgatc acacttaata ataaagcaat gaaactaatg
    12241 gttacactta ctctttcaca ttttgtcatt ttgtttcctt ctttactcgt ttgttatttc
    12301 ttgtaatagg tctaataact ccttcaccga aatttgcaaa tggttcgcaa aaatttcaat
    12361 aaaagcactc gcacacatta ccagaccttc aactgatata tcactgcgac aataaaattc
    12421 tggagaaaca ctgatttctg attctttctt acaattgaac gaaaaaacta tttttgaatc
    12481 aaattccggt aattcttcca caactatgtt ttgggattct accaagaaag ggagtgcctg
    12541 ttctaatgct tcttctggtg tttgagcaga tagaataatt gcttcttgtt cttttatttc
    12601 attgttctca aatactttat aacttttttt cattgttagt tcctctttca ttcctctctc
    12661 aattagctaa gccgttactg gtacgccatt ctctaaattt agtatcgcta atccttaatg
    12721 ctcgtcgaat atcaatcatt cgataaccta ttgcacgaag ttctttatat cttttagcag
    12781 ttagcgtctc taacgtcatt tcaggcaatg ggttcgaatc aaaaatagaa ttcgaaccga
    12841 ttatttgggc caattgttgt acttgtaaca gctcttctga acttaattca gtgattgctc
    12901 gattgcctat cattgcatac attttctgtc gaatatactt cttttcttgt ttagacaaca
    12961 tttctatcca ctcctatttt cattatcatt tgttacctcc acttcagtaa atccacaaat
    13021 aaatgaattc atattccaag taccattccc ttcaactaca acttttctcc tgtcctcttt
    13081 cggatattca agaatcagac cgtttaccaa tatgtttttc actactacta atttgtttgt
    13141 ataccgtgga attgctgttc cgatatactt cactttattt cctacgctaa ttgtcatttc
    13201 ctcactccta ttctttttta tccaaaactt tttcctgtcc tattcctgcc aacgaatata
    13261 cttcactgca tgcttaaaca aaacaaaatg ttgccctgtt ttatttccgt cttttacttg
    13321 ttccacatac agttcatatt tggtcacacc ttttaaaacg ccagatactt tttttcatcc
    13381 attgtcacaa ttagtttttt catcaatcga ttgatactgc actgctcatt tttcttgttc
    13441 atatagtatt cctttctttt tcaaaactag cctcttttgt ttactagttt tcatcaatca
    13501 tcaacgattt aacagatttt ttctttcgca gggtttctag cgtcagcaac cccaaactct
    13561 aaaaaagtgc ctttgctccc ttgaaaaacg agcggacgat tgtactcgtc atcatatgtt
    13621 tttcatacta cctgatccac gcaaataacc tttttttgtt ctgtgccaca cccatccata
    13681 cgtatcgctt gagattcacc atactttttt aggtggttta tccttcctaa gtccctgtta
    13741 gacacgctga ttaacttaga aagtcctgtt tgtatccaat tttcaaagat ctcccaaaag
    13801 aaataagtag gtttacgtgt atcgcttctg ttcaaagtac ctgtttgtac ttgagtattt
    13861 ctactcccct cgttcaaggg attccttcca ccagctagct tttcctttca tcatcaaatg
    13921 ttcctgaaaa gcatttacgt ttcgtgtccg tgtgcttact tattcttttt tcgatagcga
    13981 ttatccgctc gctactcgct attttatact ttgtttgtta gctcaaataa aaactaacaa
    14041 acaaaaaagg ctagtttctt tccgttttat ttttttaact gtcgataaat agttgttagt
    14101 ttaattccaa gttctaaaac caatacgccc aacaaaacca caggaaaaac aattggggca
    14161 aacaagtaaa atcggatagt tttcatgtct tccctctttc tttttggtgt cgctgtggtc
    14221 gttcttgccg ttcaatactt cgatacattt tttattcatt atttgctcgt tttgttttcc
    14281 tctggactgc ttttcttgct ttttgaatac tttatacgct tttcgtgcct gaattaatag
    14341 gtcttgtcgg cgtttcattc gtgagaaaac aatatttgaa accatcaaat cctggttcga
    14401 acaaccacga ttcgcaataa ttttcccatc aaaaaaaata gttttcactt gagaaaaaaa
    14461 cagttggaaa tcttgttttg ttgctaattt ttttgtcaaa atcactgtgc ttttccctgt
    14521 tgaatctaca atgattcttc gaacaatccg attcgataac ttccaacgtt gccgattaaa
    14581 caatgttact tcacaacaaa tatgacgtaa gtgattaggg gtcattttca tgtgtccaat
    14641 tcctccaacc aattatgcat cgaaattttg ggcaattgtg acagcccata aatctgcgtt
    14701 tccaggtctt cataactaca agaacgcttg gcttgaagta atgaatattc tgcttgatct
    14761 gatagttttg ttgccattgg atctagattc aattctctta cacaacattc ccaaaaattc
    14821 aatagcgctc taaaataaaa tccttttcga ttctgaattg cttttccttc atgacgagca
    14881 attttttcat tttgaataca ccgttgatac gttttgctta aatcttctgc aaatgtttcc
    14941 cctaaaattc gatactcgct tccatcagat aaaccatgtg tttgattata ctttcgttgc
    15001 cgcttttcta taattcgttt actgtcgtat atcatgttta gctgctcttt cgcttcacgc
    15061 cattcagctg aactgcgaac aatccatgtc aaaacatctt tcggaacaaa cgtactttcg
    15121 ctgtaatgag caataaactc tttttgccaa tcatcagcca tttcaacagg actagtcgta
    15181 tcgatttttg tatctagatt ttctgtatct agattgttag aagaattatt aaataattgt
    15241 gcagaatttt cacatggatt tttttcgtca aaatcatcga aaatcgctaa attatcaaca
    15301 gattcctcct cttcttttcc ttgtgcagaa tctacactgg ttgagtcaac aggacctaat
    15361 gaatacacat cattttctgt cgtatctaat tctcctagat acaaccgagc tttgtttctt
    15421 tttcctgttt gttgatcaaa tcccatatcc tctatttcta gtagctcata ttctttcaat
    15481 tcttttttga ttgtattaac agaacgtctg caacaattca atgcattggc taattcttgt
    15541 tccgtaaatt caaaataaac aaaaccttga ctatctactt gatttcgttg aatggctaaa
    15601 tctaagcgtg accgaaaaac catatacgcg atttttgctt tatcagacaa tgagcgatat
    15661 ttttcacttg taataaatac ctttggaaat tgatagtata attcattgta tttacgagtt
    15721 gcggtaaatc tttttgttgc catcgttatt acacctcatc ttgtccatat attaagaaag
    15781 aattttggtg ttggtagaca cgaacatctt ccattgtagc aatcaattct tttagataaa
    15841 ttcgaccgaa ttcaattgtt agtaagtcgt aatcttctaa ttcatttttg atttcttcaa
    15901 tttcttcttc agacacattg agtaaaatgg ctaattcttg attggtataa gaaatataga
    15961 catgtttctt ttcatcaatc cgtttttcaa ttaaggattc ttctaagtac tcattcagta
    16021 agctataggc gtattttgct tgtgcagtca tcgcataata ttttgacgat tttataaaga
    16081 atagttttgg catatgaaaa gttgcttgtg tcagcacatc tgttgcgcga aatttgtttt
    16141 ttaccatatt ttttcctcct agaaaaacac gcaaaaaaag ctctgtataa atcgaattac
    16201 acagagtttc ttcttgttga tatttaattt ctaaaatacg tttcgggtaa aaactaaaca
    16261 cttactaata tttagattgt agaatcttcg ccttcattta ttcattttaa agagaaaaag
    16321 atcaagtgaa atgtgcccaa aagtttgatt ctatta
//
LOCUS       DARBDN010000057        16191 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000057 DARBDN010000000
VERSION     DARBDN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.057"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(57..1586)
                     /gene="ahpF"
                     /locus_tag="SCH06_001830"
     CDS             complement(57..1586)
                     /gene="ahpF"
                     /locus_tag="SCH06_001830"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEG1078388.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1596..2159)
                     /gene="ahpC"
                     /locus_tag="SCH06_001831"
     CDS             complement(1596..2159)
                     /gene="ahpC"
                     /locus_tag="SCH06_001831"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEG1078389.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2303..2965)
                     /locus_tag="SCH06_001832"
     CDS             complement(2303..2965)
                     /locus_tag="SCH06_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1078390.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3149..4795
                     /locus_tag="SCH06_001833"
     CDS             3149..4795
                     /locus_tag="SCH06_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEG1078391.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4786..5868
                     /gene="uxuA"
                     /locus_tag="SCH06_001834"
     CDS             4786..5868
                     /gene="uxuA"
                     /locus_tag="SCH06_001834"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEG1078392.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5976..7529)
                     /locus_tag="SCH06_001835"
                     /pseudo
     CDS             complement(5976..7529)
                     /locus_tag="SCH06_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7677..8818
                     /locus_tag="SCH06_001836"
                     /pseudo
     CDS             7677..8818
                     /locus_tag="SCH06_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8944..10023)
                     /locus_tag="SCH06_001837"
     CDS             complement(8944..10023)
                     /locus_tag="SCH06_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEG1078393.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10126..10566)
                     /locus_tag="SCH06_001838"
     CDS             complement(10126..10566)
                     /locus_tag="SCH06_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1078394.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10623..11033)
                     /locus_tag="SCH06_001839"
     CDS             complement(10623..11033)
                     /locus_tag="SCH06_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEG1078395.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11213..11647)
                     /locus_tag="SCH06_001840"
     CDS             complement(11213..11647)
                     /locus_tag="SCH06_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1078396.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11747..12595)
                     /locus_tag="SCH06_001841"
     CDS             complement(11747..12595)
                     /locus_tag="SCH06_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1078397.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            12984..14750
                     /locus_tag="SCH06_001842"
     CDS             12984..14750
                     /locus_tag="SCH06_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEG1078398.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            14852..16111
                     /locus_tag="SCH06_001843"
     CDS             14852..16111
                     /locus_tag="SCH06_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEG1078399.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
BASE COUNT         5502 a         2924 c         2979 g         4786 t
ORIGIN      
        1 aaaattcttg tcaccatcct tttttccgct ctctgacttt ttacaatctt catagctcaa
       61 gtgcgcatca gataatcgaa tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca
      121 atgatttgtt tgtatggact atctgtacaa tcaccagctg cgaaaacgcc ggggatattc
      181 gttgcgccat ttttctcggt cactatttca tttcttggat tcatttcgat cgttccatct
      241 agccaatccg tattagggag taagccgact agaatgaata ctcctgaaac agctagtgta
      301 tgcatctcca tcgtacggcg atcgatatag gagagagatt ctacctgatt cgtaccgctg
      361 atttctttcg tcgctgcatg tttgataaca gtgacattcg caagagagac tagtttatcc
      421 tgtaagattt gatctgcttt taattctggt aagaattcta gaacatatac atgttttgct
      481 aacccagcca aatcgattgc tgcttcaaca ccagaattac caccaccgat aacagcaatc
      541 tcttttcctt taaataaagg gccgtcacag tgtgggcaat aagcaattcc tttattttta
      601 aactcttttt cgcctggtac attgatagaa cgccagtgcg cacctgtcgc gatgatggcg
      661 gtttttgctt taagtgatat accgttagct aagccaatat taataaaatg ttgctcttta
      721 tttaaggaaa cggcctgttg attcatcata atgtcgatag ggtaactacg cacatgactt
      781 tctacttgct gcatcaattt tggaccttct gtgtaagagg taccaatcat attttcaatc
      841 cctagtgttt caacgacttg tccgccgaaa gaatcagcga caagtcctgt acggattcct
      901 ttacgtgctg catagatagc tgcactacta gctgctggtc caccgccaat cactaataca
      961 tcataaggtt ctttttcaaa caactcttct tcaatcaaag ggccagtgat tttttcaaca
     1021 atttgttcga tcgtcatgcg tccgctacta aattcttctc catttaaaaa cacagttggc
     1081 actgccatga tttttttatc atcgatttct ttttggaaca tcccaccttc aatcatcgta
     1141 tgagtaatat ttggatttaa tacagctaat atattcaatg cctgtacaac gtcggggcaa
     1201 ttatgacaag tcaagctaac ataactgtca aaatgcaatg tttgtgttat ttttttgatt
     1261 ttaagactca aagattcact gattttcggt gcccgtccac taatttgtaa catagccagt
     1321 aaaaaagagg aaaattcatg accgaggggg ataccagcaa aaacgattcc actttctttg
     1381 ccaactggat tgatagaaaa actaggtgtg cgcatcgaat ctcttttttc ccaagagatt
     1441 ttaggagaca tttctgctat ttccttcgta aattcagcta gtttttgact attttcacta
     1501 ttatccaaac taacagaaaa aacaatagga gattcaatca gtgctaaata ttgttcgaga
     1561 ttttgtttag tttctttgtc taacatatcc accacctaaa tctttccaac aagatcaaaa
     1621 cttggtttca atgtttcgcc actttctttc cattttgccg gacaaacttc acctgggtgg
     1681 gtacgtacat attgagcagc gcgaatctta tcaatcagtg cactagcgtc acgaccgatt
     1741 ccatctgcat tgatttccat agcttgaacg attccgtctg gatcaataat aaatgttcct
     1801 cgctgagcta atccttgctc ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac
     1861 ggatcaccga tcatcacgta ttcgatttta ccgatagcat ctgatgtatc atgccatgct
     1921 ttgtgagtaa agtgggtatc ggtagagcaa gaaaagactt caacacctaa agatttcaat
     1981 gtactgtatt gttcttgtaa gtcttctaat tcagtaggac aaacaaaagt aaaatcagct
     2041 ggatagaagc aaagaatact ccagttcccc ataagatctt tttcactgac ttctaaaaat
     2101 tctccttgat gataagcatg tgcattaaat tcttcgattt ttttcccaat caatgacata
     2161 gtaaaacctc caataataat tatttattta taattattgt aatttagttg gagttgcaaa
     2221 gtcaatggat attttgttat ttaataaaga ttactcaaaa acgaaggtta attataaaaa
     2281 tagaagaggt cgcaagaaaa tgctactgct ggaaatactc gggataacgt tgagtaacag
     2341 tttcctgttc tttcagcatc atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg
     2401 gttttttatc aactaaagcc ttgagtaaat cataatgttg ttccatgatc gtttcccatg
     2461 gaagcccctg aatggtcact cgtaaccagc ggaaacgttc taaatgggta ttatggtcat
     2521 ctaaccagtt ccaaacttct tttcttcctg caatttcgaa acaagcttca tgaaataaat
     2581 tatctgcacg gaaaaaagcg cgttcgtcat ttattttgac tgctttttct tgttcttcta
     2641 aaatcgtttc tagcactatt cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga
     2701 tttgctcttc caactgttct cggacaaagc gagcattttc tgcagaaaca agattaattt
     2761 tggaaacata cgtaccactt tgaggtatcg tatacacgag ttcttgctga cgtagttgaa
     2821 tcaatgcttc gcgaatggga gtccggccga tagcaagatg ttcctccagt gccttttcag
     2881 atattttcct tccaggttct aagtcagcat agataatttg tttacgaatc gcttgataag
     2941 cttgtgattg caagctgctt ttcatcttta ttcctccaaa atcatttcta tgaacgtagt
     3001 ataacagaag aggtctgaaa aacaatctgg tatgtcacat taactagtaa atttgtataa
     3061 atagtaaaat tttggttgac atagcgattt ttattgcata aaattcactt gaatacaaaa
     3121 actaatatgt tagtttagga ggggaaaaat gattgattta aacaactgga ggaactttat
     3181 ccctgaatta tctcaaaaag aagtagaaat acctcatttt gaccgtgcat cattaagaga
     3241 aaatggacaa aaaaatcctg tctggatcca tttcggtggc ggaaatcttt atcgaggatt
     3301 tcatgcagaa atcgctcaac gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt
     3361 ttgtgaaaca ttcgatgaag aaataattga aagggcttac caagattttg atgatttgat
     3421 tcttgaagtg gtcatgccaa gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc
     3481 tgacagtctg tattgtcatc cagattgttc tgaacacttt gataagatga ttcgacactt
     3541 tgaaaatcct agtttacaat tagttacttt tgctattact gaaaaaggtt atcgattgaa
     3601 agatacaaat aataaatata taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa
     3661 gccatcacat acaatgagta ttcttgctgt gctactttat aaacgttttt tatctggagc
     3721 ttggccgatt gcacttgtct ctacagataa tttttcacaa aacggtagtc aattacgtac
     3781 ttctttgcta acgatcgcaa aagaatggca aaaggaaggt tatgtacaaa atacatttat
     3841 ccaatactta tcgaatgaag aaattgttgc gtttccatgg acgatgattg atcgtatcac
     3901 cccgaatcct tccttgtcag ttagcaaaat gttggcaaaa gagggctttt caaatatgtc
     3961 gattttccaa accgcaaaag gaaataatat tgctccattt gtcaatacag aggacatcca
     4021 ttatttaatc atggaagatc attttcccaa tggacgtccg aaattcgaaa aagctggggt
     4081 attcttgact gatcgtgcaa cggtagataa agcagatacg atgaaggtga cgacttgcct
     4141 taatcctttg catacgtctt tagctattat gggttgttta ctggggtata ggagcatagc
     4201 tgaggagatg aaagatccag atttatcgct gctagtttct gaaatcgggt acaatgaagg
     4261 cctcccagtt gtggagtctc caggtatcat tgatccaaag atctttctgg aagaagtaat
     4321 tactgtgcgc ttttctaatc caaatattcc taatatgcct cagcgaatcg ccacggatac
     4381 ctctcaaaag gtggcgattc gttatggtga gacgattaaa aaatatatgg aaatagaagt
     4441 taaagacccg cagacacttg tattcatacc attgactctc gctgcttggc ttcgatacct
     4501 tattggcatt gatgatcaag gaaaaccatt catcccgagt ccagacccac tattgacaga
     4561 ccttcagcat aagctttccg atattcaact gggtacgcaa gatacatcac atattcatga
     4621 gaaaatggct cctattttgt caaataaaga aatttttggt gtagatcttt accaagcaga
     4681 gcttggcaga aaaatagaag aaatgttcat caagatggta gcaggaccaa atgccgtacg
     4741 aaaaacatta caggattact tacaagaaca tggaggaaat ttatcatgga aatgactttt
     4801 agatggtacg gatcacagga agaaaagatt accttagatg aaatcagaca gattcctgcg
     4861 gtcaaaggga ttgtaggcac attgatggat ataccagtag gagaggtatg gcctagggag
     4921 aggatcaaag aactaaaaga agaaattgag tctcgtgggt taacactaaa agtaattgaa
     4981 agcgtcaatg tgcatgatgc cattaaaatt ggattacctt cccgtgagca gtatatcgaa
     5041 aactataagc agacaatccg aaacttggca gaatatggaa tagaagtcat ctgctataat
     5101 tttatgcctg tatttgactg ggtgaaatct gaccttgact accgcttaga agacggctca
     5161 tccacgttag cttttatatc tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc
     5221 atcgaacatt ccagcaatga atttggattg ccgggatggg aacctgagcg cttagctcct
     5281 atcaaatcct tgcttgaagc ctatgcatca gtagacgaag aaaaacttcg agaaaatttt
     5341 gcctattttc tccaatcaat catcccaaca tgtgaagagg taggggtcaa aatggctgta
     5401 catccagatg atccgccata ctcgattttt ggattagctc gaatcgtaaa gaatcgagaa
     5461 gatttagatt ggttgtgtcg catagtagac agcccttata acggaatcac tctttgtaca
     5521 gggagtattg cagaagatcc agaaaatgat gtatatggga ttttagcaga attttgccaa
     5581 agagatcgaa tcccatttgc acatgttcga aatattaaat ttttagctaa tcgagatttc
     5641 tatgaggcac cacataaatc cgaatacggt tcattagaca tgtaccgcat actaaaaaca
     5701 atgtatgaca acggatttaa cggatacatc cgtcctgatc atggaagaat gatctggaat
     5761 gagacaggaa gaccaggata cggcttatat gatcgagcat taggtgctgt ttatctaaat
     5821 ggattatggg aagcaatcga aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg
     5881 taattttatt atgtaaataa gaaggatgtt caaattcttg atacataaat ccggaggttg
     5941 ttaataagca ttcggattta tgtatcttat ttggtctagg aagtaacttg attttctttt
     6001 ttcgattgat ccatgagtgc ttcttctttt aattcaaaga tatattctga gatcctcata
     6061 atcacttttt tccagtcttc tggtgtgatg attcctttta aaatatagat ttttttgata
     6121 tgagaaggca attgtttcaa agggcagtcg ctgataacga tgttgcagtt ctccataaaa
     6181 tcattttgta ttttgatcga ttcatttgaa aaaatttgtt ctatcttaac gatcagatct
     6241 ttactgatat aaaaatcacg cgtatagttc acaccaatca caattcgcgg ctgttttttg
     6301 tagcgatcat acaaatgtac taggtcttca accatccatt gcacattttc cttttctaaa
     6361 ataactggta acaagtgttg attttgttct ctgaaatcca tataaaattg ttcaatggcg
     6421 gtttggactt ctttcaatac gctatgttct tgataaagca tgaaagtagg aaggggcgta
     6481 tttggttgat tgaagttaag aaatccatta taaagtttat ttcgtgcgaa tgccaatgag
     6541 taaagaatct tttctttttc aggtataaac aaatcaaata cagtacaaag ggactccacc
     6601 atttctcttg aataaagaac atgaggaacg tttgcttttt ttaaaagttt gtattgctcc
     6661 aagcttgttt cttccgattc gattttcgtg atagaaagtc gagctaaaat attcactaag
     6721 atgcgttgtt cgcgacaaat tggcagatta ggtcgcaaaa tatctacaga gagatcaata
     6781 aaaaagtcaa tatattcata ctctgtgaat tctttttgta cgtctttcac agaagttgca
     6841 ggaaaattct ctttacatat ttttaataga aaatataatt tatctatcat accgctattt
     6901 agtcggtcaa gtacttcttt tttaaaaaaa gtattcatca taaaagccac tacttgcgga
     6961 tcttcatcat aaaattctgt agcagtactt gaaaagatgt tccaataaat atctaatgct
     7021 gcatattgaa tttgtacctc ttttccagaa aaagactttc tgccattatt agaaaaggag
     7081 atagacaaac cgtactatgc taaaaatgca ttaatctttt tcattttcgt atacaaataa
     7141 gaggcactat agtttgtttg ctgactgaaa ctgataatcg aatttgtctg acagctgaac
     7201 aaagaagtca agatctgata actgactgat tcgttgcagt atcttccaaa tagacgataa
     7261 tagcagtaag ccggatcaat tccttcaaaa ttcaacttta aaaaaggttt ttgcttatca
     7321 atatgcagtt ctgttagatt gagacgctca aagtcttgtt ctaattcttt gatgtatagt
     7381 aaaaaatttg attcagacat atggaaatga tctgctaaat attgtgtagt aataaagaaa
     7441 cgatgttcag ataggaaaag aaaaatatct aattttgtat tgcttttttt cttcaagata
     7501 aacgttttaa tcgcttcttg agtttgcatg aaagaggctc ctttttactt aaattgttaa
     7561 aacttgaaaa tattactgtt tttttcataa atttagacaa aaaaacagta aacatatagg
     7621 tagaatctct actatcttat ttcttgcata caaaaaaatc aaggagtgag agagttatga
     7681 gatattcaac catcttaata tcaacatttg cagccttaag cttatcgctt actataaatc
     7741 agacagtcca cacagaggag acagaaacag ccaaatggac agaaaccaag tgggccaacg
     7801 tcaatcgaat tacctttcag gatgaatttt catccttcaa ttcaggagtc gcaaaattaa
     7861 gaaaaggaca aacagcgacc atcaaagcaa aaattgacta ttcgggagac ttagcaccta
     7921 tactacaatc agctgttaca tttgagaatg ttgatcccac tttgtcgatt ggctatgacg
     7981 agaacacttt gactatccaa cacaagcaag cgatatttac cttcaccgtt acattaaatc
     8041 aggacttgtt aaaaccagcg ctttttactg tcaaggtatc agatggacta ccgaacgatc
     8101 atcatttaac gccgtatagt cagcggcaga caattgagca agattcagcc atcgactcag
     8161 gaggagatct tgttgaagaa ccaacagata aaccagaaaa tgaaaataag ccagaagtac
     8221 cgcctacaga aaatccagac ggagaacaga aaccggaaat agaacctgga gaagaacccg
     8281 atacagaaac tcaaccagag ccagacaata aatcaaaacc tgaaataacc cctggagaaa
     8341 aaccagatgt aactccagaa ccagatacgg attctggaaa ccaaacagta ccggaaacaa
     8401 atccagacac agataatgaa actgaaaatc cagaaaaacc agaggtagat ccagaagaaa
     8461 aaccagatgt gactccagaa ccagatacgg acgcaagaga ccaaggaata ccagaaaaaa
     8521 taaacaaaaa aacaattcaa gaggatggaa aaaaagagag taaaaaatca aatctagcaa
     8581 ttctaaaaat aaatgaagag cagctgaata aaaaatcacg aatatttgat agcgcccaat
     8641 cagctgaaac cttaaaaagt agcaaggata caacctttgc tgtcctgaaa cgaaaaataa
     8701 acagctacca aaatccggag agtcacaaaa caaagttata ctgtggagcg gaatcattct
     8761 attaagtata gcaacaatgc tttctgcaaa aagatttaaa caaaacagat ctctctaaca
     8821 tttgaataat gtctgtgaac gcatttttca aataaaaaga aatatccaga aaatgacccc
     8881 aaaataccag attgaaatct gatatttggg gtcgttcata ctttatcttt cttcatattt
     8941 attttaaggg atatctgttt cttttggaag atggttcggg atctttttca ctttcaatac
     9001 atctaaaaag aaggtaaaga tcggaatgcc gacaatcaag ccccaaacgc caaagaaccg
     9061 ttcgctaaca agtaagacca caaatgtata aaaaatcggc agttctgttt tgctggacat
     9121 caacttcgga ttcagcacat aagactcaat tagatggaca atcaaaatcg taatcaggat
     9181 ataaacaaca tctcggatgc ctccttggga ataagctatg aaagatagag gaatacaaga
     9241 aatgataaca cctgctactg ggatcagact taaaatgaaa atcatgatcg ctaaactcag
     9301 cagctgatga aagccaaata cagccaaggc gattgtagtg agcaacgtat ttaaaagagc
     9361 gacaacaaat tgagcttcta ataccaaacc aaatgtattg acaaacttat cggcaaaata
     9421 gtaaatatct tgaaagaacc aagaaaattc actttttaaa aacaatcttg agaatacaat
     9481 tgtttttttc ttttcaatca taaaaaagaa acttaagatg aatgacatag caaacgccac
     9541 tgccattttt cctatatcct gtaaatagcc aagcgcaatc gaagcgccat tttgaagctg
     9601 ttcaaaaaaa tcgtttcgct caatataagt atggatatat tgtaaaacag gatctgcatc
     9661 ttttggctga tgctcgtaaa aattaataac ggactggatc atgtcaaatg tttgatgaat
     9721 aagcatcggg atatactttg tgaatgccag atagataagg taaacgatca gtgtataaat
     9781 catgatagct aaaacacctg tagggattcg gacaaatcgc tgaatgattt gaacaagatg
     9841 aatcatcaaa taagtaaaga taaatgtgag caaaatggtt gtaatcatac ttctaactaa
     9901 gaaaagaaca aaaacgacaa ataataaaac agtgagacgg cgtatttttt cattcgccaa
     9961 aaaacgctga taaacggtca aatcgacaac ctccaaataa caaaaaataa acacgttatt
    10021 cattatatga tggaatatga aaataagaaa gagcaaaaag aaaaaccgct aaatgacgtt
    10081 atcttatgag ttggttttcc tcataaaatc gttcatctag cagtttcagc cctttttctg
    10141 gtcttgatga aaattatcta gcatttttcg ggtcagatgt tgcagtgtat ccaattcttc
    10201 ctgttcaagt ggaagataag acttgatctt ttgtggaata ccttctgctt gtttttgcaa
    10261 cgcagcacct tgagcagtca gcgtaacatt tacgattctt tcatcacccg tttcacgctg
    10321 acgattaata taattttttt ctgctaactt ttttagtaag ggagtcagcg taccagaatc
    10381 cagacacaaa tcatttccta gctctttcac tgaagtcttt ttcttttccc ataaaactaa
    10441 catcacaaga tactgggtat aggtaagatt cagcggcttg aggaggggag tgtagtgtct
    10501 aatgatttct ttagaggcgg catataaagg aaaacatact tgattaacta aatatagatc
    10561 ttccattttt ccacctccgc tgttttacta tagtgtatca tagcggattt acacaaaaaa
    10621 gtctattcac taactgcttt cagagtaact tctatatttc cagctgtagc ttttgaatac
    10681 ggacacactt tatgcgctgc ctctaataat tcttgcgttt cttccagaga aagaccttcg
    10741 atagatcctt caatctctac acctaagaca aagctcgttt cactttctga ataaagggaa
    10801 acttgtgcac tgacagtaga agccccagag atattttttt gctgtttgat caattctaat
    10861 gcactgttaa aacatgcact gaaaccagct gcaaacaatt gttcagggtt ggttgcattt
    10921 tcgacgcgtt taccaggagc tgcaatattc aattcgaatg tacgatcggg attatgcact
    10981 tctccagagc gtccgcctgt gttgatcatt ttcgtagaat acattttttt cataaaatta
    11041 ccacctttaa ttatatttta tacaattgaa ttttacacaa tataattgtg gaaagcaaag
    11101 aaatggattg gcataagata aataagagaa agcacatgaa acagacgcgc tttctcgaat
    11161 agcaaacata tacaaaaaat atcagagaca aaaaataatc tcatcataaa cattacatat
    11221 atttctcaaa aagttgtttt ctttcttcaa aaattacttc acgatggacc tgatgaagca
    11281 tccataaata accaaaagga tctctgaaca ttgagttagt cacaccaaag tccatcattt
    11341 ctgtcatttc ttgaatctct acacagccat ttcgtaatgc tttattatgt gtgtcctcga
    11401 tatcagagac gatgatattg aaccagatcg tatttggatg ttcagcagta ggagcagtca
    11461 aaccaagaga cgtgttttca tccagcatat ggaatctcgt accatacaag gtaaaaatga
    11521 cttcattatt gcctctaggg taatctgttg cctcaatcag ttgtatttca tcaaagattg
    11581 tttgatacag ttctagtgct ttcaaactat catttaatac aaaatcgatt tccgttcctt
    11641 tatgcataaa gatctcctct ccttttcagt cgaacagtta ctagattctt ttattatacc
    11701 agctaaagaa aacgcattca aaaaaatagc ggatttactt accaactcat tcgattggat
    11761 gataagtaaa tccgcgtccc attacttctg ctacgctgct gacaatgaca aaggcacttg
    11821 gatcgatttc ttctatcaat ggtttcattc gggaaaattc atgatcagtc acaacgatca
    11881 ataaaacctc ttttgacttt cgattatacc cgccttttgc ctctagcagg gtaaggccac
    11941 gtccaatctc agcacttaag cgaaggcgga tgtcttccaa ataatgttca ctcatgacca
    12001 taacagattt ctttcgattg atacctgttt cgatataagt catgacaatt gaagtgattg
    12061 caatagataa aatagcataa agaaactctt ctattccaaa aataaacaga ttaagagaaa
    12121 caacgaatgc gtctgtaaaa aataagccaa tcgaagtatt caagtggaaa tattttttaa
    12181 aaatgagggg agggatcgtc gtaccgccgc tagaagagtt gtttttatat aaaatcgcaa
    12241 ctcctaaagc aaaaatcgca cttccaaaaa tgacagacaa caaccgatct gaagtaatca
    12301 ttgtttctgg aactattgca atgattaaag gaaaaaccaa gcttccgaaa agtactttaa
    12361 aaaagggttt tttacctaaa aatagaagag ctagtaccaa cataacgata ttcaacacta
    12421 aaataactat agctcggtca aagcctaaag cagcttccag taatattcct agaccgctga
    12481 cacctccagc agcaatatga tgaggcccta aaaacatatt gatagcgact cctaatatga
    12541 agagggcaaa aataatctta atgtatgtcc atataaattg tctcgtttct ttcatttatt
    12601 cacttcctta attcattaat aatactctta tcttattata acttactttt caccttaagt
    12661 taactttaat taataaaaaa attaggctag tctaaattat tatgtttcat tcttctagaa
    12721 tatacttcta cgccaaaaac tgttaaaaaa cttttacttt agaaaattgg agaaattgat
    12781 cgcttaagat aaattcagga cactaaatag tacaggaagt agactaaaac ttttaaaagt
    12841 tttaagtcta tctatttggc aagtttaaaa aataaaaatt cggtatcaaa aaactgttac
    12901 cgataacatt tttgaaagcg ttgtcttttg cttctctatc acttatagtg atgacgtcat
    12961 attaaaacac aaggaggaaa tcaatggata cagctgcaat ttatcatcga ccggaaagtg
    13021 aatatgcatt tctatatacg aatacaagat ttcgtattcg gcttcgtact aggaaaaatg
    13081 atatcaaaaa agtatatgtg ctatgtggag atccatatac cataacaact gaaaaatggt
    13141 atcaaaaaca acgaccaatg aaaaaatgtc taagtaccaa tgttcatgat tattgggaaa
    13201 ttgaagtgac gagcgaaaca agtcgcttac agtatgcgtt ccatgttgtt ggggaagata
    13261 acacggactg tttttacggt gatcaaggaa tttttcctta tcgagaaaat gtgattactg
    13321 aaccaaattt ttattttcga ataccttatt ttcatcaaat cgatcgattc actattccag
    13381 aatgggtaaa agaaacagta tggtatcaaa tttttcccga aagatttgca aacggggaca
    13441 aagcaaatga ccccgaacac actttacctt ggggaagtaa agatccagac cgagaagact
    13501 ttttcggggg agatttgcaa ggtgtgatgg atcatttgga ttacttgacg gaccttggca
    13561 tcaatggcat ctatttttgt cccatattta aagccacatc caatcataaa tacgatacga
    13621 ttgattatta tgaggtggat cccgcttttg gcgataaaaa acttttaaaa aacttgattg
    13681 atgaagcaca taaaagaggg atacgtatca tgttcgatgc tgtattcaat catatgggtg
    13741 tccattcacc acagtggcaa gacgttctca aaaacggaga aaaatcgatc tataaagact
    13801 ggttccacat ccgttttttc ccagtagatt cttatcagat gactgactta ccagaaactg
    13861 ctgaaaatat cccatatgat acttttgctt ttactccatt catgccgaaa ctaaatacag
    13921 caaatccaga agtgcaaaaa tatttgctgg atatcgcaac ttattggata aaagaattcg
    13981 atattgatgg atggcgtctt gatgttgcta atgaagtcga tcatcatttt tggaaaaaat
    14041 tcagagaagc agttacagaa atcaaaccag acatctatat ccttggagag atttggcatt
    14101 cctctcaagc ttggctgcaa ggggatgaat tccatgcagt gatgaattat gcatttacag
    14161 attcgattaa agattatttt gcaaaaaaga aaatcacagc ttcacaaatg gtcagtggaa
    14221 tgaatcatca gcaaatgctt tacagagatc aggtgaacga aggaacattc aacttattag
    14281 attctcatga tactgccagg atcttgaccc tttgccaagg taacaaagaa ttgatgaagt
    14341 ctgtgatggc ctttatgttt cttcaaaaag ggtctccttg tatctattac gggacagaaa
    14401 tagggatgac tggtgaagat gacccggatt gccgcaaatg tatgatatgg gagaaggagg
    14461 aacaagatct agagctattc ggttttataa aagaacttgt ttctctaagg aaacagttgt
    14521 ctaagattat ttctgaaggt tctactcagt ggctaatagt aaatgatcgt gaagataagc
    14581 tctatttcac acggaaacta gagggacaga tcatctatgt ttactttaat cagtcaaaag
    14641 aaccttgggt agtagaacag gaaaatgagg tgattcttag tcaaaattgt cagttgttag
    14701 aagacgggaa agcagagata cgacaatacg gatttttgat catgtgttga aaactgttac
    14761 cggtaacaac aagaaagcgt ttgcaaatga agatttgtgc ccattataat aagggtgtaa
    14821 cagcacgttg aatacaaagg aggaaatgaa gatgaaaaaa agaagtgtga aacagttggg
    14881 tttagggtta atctctttag gaatcttagg cggattagcg gcttgtggca atggtaactc
    14941 ttcagcagaa ggggaagccg atgaaggaaa aacgttaaca gtttccgttg attctggata
    15001 taaagattat ataaacgaaa taaaaaacac tttcgaaaaa gaaaacgatg tgaaaatcaa
    15061 gctagtagaa aaggacatgt tcgatcagtt ggaatcatta gcgttagatg ggcctgctgg
    15121 aaagggacct gacgttatga tggcagcata tgaccggatc ggtgcgttag gacagcaagg
    15181 acatctggcg gaagtaaaac tgggaaatga agcagcttac gatgaaacag acaaagccca
    15241 agtgacttat gatggaaaaa tctacggaga acctgcagta atcgagaccc ttgttttgta
    15301 ctataacaaa gatttagtcg atacagcacc atcaacgttt aaagatttgg agaatctatc
    15361 caaagacagt cgttttgctt ttgagtcaga agcaggaaaa aatacaggat ttttagctaa
    15421 atggactgac ttttattatt cctatggttt aattgcaggt tacggtggct atgtatttgg
    15481 tgatgatggc acaaatcctt cagatatcgg tttgaataat gcaggtgctg tagaaggaat
    15541 ctcttatgca acagattggt tcaaaaatgt ttggccaaag ggaatgcaag acataaaaag
    15601 tgcaggagac ttcgccagcc agcaattcat gtccaataaa actgcagcaa tcattgacgg
    15661 tccatggcaa gcgcaaacat acaaagaaaa caatatcaat tatggtgtag ccaaaattcc
    15721 tactctaaat aatggacagc cttatcaacc gtttggcgga ggaaaaggat gggtagtcag
    15781 caattatgct aaaaacaaag acctctctca aaaatggctt gattatgtaa cgaatcagga
    15841 aaatcaagaa aaattctttg aaatggtaaa tgaaatccct gcaaaccaac aagctaggga
    15901 aacagcaaag gctaaaaacg atgaattaac aacagctgtg attgaacaat atgaaacagc
    15961 tcaagcgatg ccaaacatcc cagaaatggg cgaagtttgg acaggtgcag aaaacttgat
    16021 gttcgatgca gcatcaggtt caaaaacacc aaaagaatcc gcagatgaag cagtaaaaac
    16081 aatcagtgaa gccatagaac aaaaatactg attaaaatga taaccgtcca tttttataaa
    16141 aaatggaaca ggtgcttcag ataaaagtgg caagagcgag atggaaaatt a
//
LOCUS       DARBDN010000058        16156 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000058 DARBDN010000000
VERSION     DARBDN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.058"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            226..894
                     /locus_tag="SCH06_001844"
     CDS             226..894
                     /locus_tag="SCH06_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEG1078400.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFSLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1480)
                     /locus_tag="SCH06_001845"
     CDS             complement(1094..1480)
                     /locus_tag="SCH06_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078401.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1452..2834)
                     /locus_tag="SCH06_001846"
     CDS             complement(1452..2834)
                     /locus_tag="SCH06_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEG1078402.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2990..4177)
                     /locus_tag="SCH06_001847"
     CDS             complement(2990..4177)
                     /locus_tag="SCH06_001847"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEG1078403.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4184..5215)
                     /locus_tag="SCH06_001848"
     CDS             complement(4184..5215)
                     /locus_tag="SCH06_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEG1078404.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVGIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5231..6685)
                     /locus_tag="SCH06_001849"
     CDS             complement(5231..6685)
                     /locus_tag="SCH06_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1078405.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEELENKLAPADTMEDELHDAVVPSH"
     gene            6860..7765
                     /locus_tag="SCH06_001850"
     CDS             6860..7765
                     /locus_tag="SCH06_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEG1078406.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7856..8533
                     /locus_tag="SCH06_001851"
     CDS             7856..8533
                     /locus_tag="SCH06_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEG1078407.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8530..8700
                     /locus_tag="SCH06_001852"
     CDS             8530..8700
                     /locus_tag="SCH06_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078408.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8814..9710
                     /locus_tag="SCH06_001853"
     CDS             8814..9710
                     /locus_tag="SCH06_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1078409.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9765..11135)
                     /locus_tag="SCH06_001854"
     CDS             complement(9765..11135)
                     /locus_tag="SCH06_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1078410.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11373..12119
                     /locus_tag="SCH06_001855"
     CDS             11373..12119
                     /locus_tag="SCH06_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEG1078411.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12116..12955
                     /locus_tag="SCH06_001856"
     CDS             12116..12955
                     /locus_tag="SCH06_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEG1078412.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12956..13906
                     /locus_tag="SCH06_001857"
     CDS             12956..13906
                     /locus_tag="SCH06_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEG1078413.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14047..14799
                     /locus_tag="SCH06_001858"
     CDS             14047..14799
                     /locus_tag="SCH06_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078414.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14818..15969
                     /gene="queG"
                     /locus_tag="SCH06_001859"
     CDS             14818..15969
                     /gene="queG"
                     /locus_tag="SCH06_001859"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEG1078415.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEVYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5244 a         3016 c         3242 g         4654 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttctcttg aaaatgccaa acatgttatc ctagagaatg ctggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt
     1381 tgactagttc ttccatcgca aaagcagtcc cccattttaa tccaaatggc cgatctcgat
     1441 actcgttata gtcaatgaat ttttttgctg tccgtctcat cttttccacc ttctaatcca
     1501 ctcataccac ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg tcctccttgc
     1561 aagagactat gcgcatggat gattgattga aagccgtatt tttttctaat cgtatcgaca
     1621 acaaaatcaa ctttcgcttc atttatctgc ttttcaggat cttcaaaaag gttaagctgt
     1681 aaacctgtcg cgtatacgag gtcggaacag ttcacgccta cacgccgaat atcctggtag
     1741 tggtaatgct ggtggaaaat ggtcaataaa gcatctgcta gatctctgct agcatttgtc
     1801 gcttcgattt tcatttgctg gtgaaacccg gtcttgccat ttggatcaag atagcctaaa
     1861 gagtatccta cccataagct gactacttgt gtttttgctg cagatcgtct caagcgagtg
     1921 ccgacttggt cggccatttc tttgataacg atctcgattt cttctcgtct tgtataatct
     1981 ctatctagga tttgactatt tccgatactt tttgattttg gtgtatattc ttgtcccaaa
     2041 aaacttcgat cgatgcccca agcatgggca taaagctgag taccgatgac ccctagcttg
     2101 cttttcaagt gataataatc cgcgtgagct aaatcataaa cagaatgtat acccatttgt
     2161 ttcagacgtt ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc tgagattttc
     2221 cataactttt ctggtacatc ttcataacgc cattcagcaa acatttgctt tccgtctttt
     2281 gagccattgt ctaaggctag tttagcaagt agcgggttat cgccaattcc tatagtcgtg
     2341 tagattccgg tctgctcaaa cacatcttta tggatcagtt tagccatgtc gtacgcattt
     2401 gttttaccaa agagtgccat gctatttgtt acatcaagga agctttcatc gacggaatag
     2461 acatgatggt tcgcttcgtc tgcatatttt ttatagatag aattgatttc tctgttcttt
     2521 tccatataat aggccatcct tggggcaaca atatataaat cacttggata ggggaaggga
     2581 agatctctgg cacggctgat attggtgatg ccgtaagctt tttttgctgc aggactggaa
     2641 gccaagatta atccgctacc ccgtgtttct gtcgaatcgg acggatagga catgactact
     2701 aatttagttg taaggggatc aagatccttt tcaacgcact ctacggaggc gtaaaaagat
     2761 ttgcagtcaa tacataaaat atctcttgaa ggttcttttt cataaacaaa taccggattt
     2821 tgattcgccc acataacaat cacctcttca acacaattag aacacacgtt ctctttccgt
     2881 gtcaataaaa aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg aaattgctga
     2941 gaggttattt ttatctattt gtttttagct gagatcgttg atttttttat caaacatgaa
     3001 cagcttctgg atcgatcttt gttgtcccat ttccaatgtg tgcaacataa aattccggag
     3061 catagccgac aactttcatg tattcatcat agacattgtt tttgaaggca ggtatatttt
     3121 cttctttgac aagagcaatc gcacagccac caaatccagc tcctgtcatt cgtgcaccta
     3181 agacaccttc ttgtttttga gcagcatcta ctagtgtatc taattcgatc ccagttactt
     3241 cataatcata gcgaagagag tggtgagaat catttaacag ttgaccaaat gcttctaagt
     3301 tcccagcttc taattcagct tttgccttca aagtccgctg attttcagaa acggcatggc
     3361 gagctctgcg tatcaatgta tcatcgccga tttggtcaat agttgattca aattcttctt
     3421 catctaagtc tcctaaagaa gagataggca aagttttttg caaacgtgcc aaggcttctt
     3481 cgcattcgct acggcgttca ttgtattttg aatctgccaa ttcccgccgc ttattcgtat
     3541 tcatgatgac gattgcataa ccatctagtt tcactggaac catttcgtat ttcagcgtat
     3601 ttgtatctaa taagattgca tgatctagct caccgaagcc gatggcaaac tgatccatga
     3661 tacctgaatt gacaccgatg aattcatttt ctactttttt acctgtttgg actagttcca
     3721 agcgatctgt ttttaaatca aacagatctt ctaatacaac acctactaat aattctaatg
     3781 aagcgctact ggaaagtcct gcaccattag ggattgttcc ttccactaac aactcaaacc
     3841 catgatcgat tgagtgtcca gcttctttta atttaaggac cattcctttt acgtaatttg
     3901 cccagtttgc ttttttatca tattctagct catctaaagt aaaactaatg acaccgatat
     3961 cgtcaaagtt tgtggaataa actaatattt tattatcgtc tcgaggtgct gctacacctt
     4021 gcgttccata agtgatggaa gcggggaaga catggcctcc attgtaatct gtgtgttcac
     4081 caatcaaatt gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt ccgaatgttt
     4141 cggcaaattt tgtgtttaag cttcttttga tttccatgat gagttattcc tttcttgttt
     4201 tgattttgaa ttctgtcact gtttcaaata ctgatccagc ttttaaatga atcgaaccaa
     4261 atgctgagaa gcgctctgca cctggagctg tttgagtctc aaatgtgatg ccaccgtgat
     4321 gtgccagttt tcggttgcgc atttctggtg tttctgtgcc gaaatttgca gtgaaaataa
     4381 ccacactaga agcatctgta gcaataccta cttggattct tttatcgggg ctagtcaagc
     4441 gagcggcttc tttacccaag ccggtttctt ttaagaaaaa tggatgatcg attccgtcaa
     4501 caagattttt ttgatccaaa tcactagcaa aaacggacgc taatttttta ggtatttgaa
     4561 aatcgaaagc acttcctgca gcattttctt ttacccctat aggaatacta tctgttcgca
     4621 aaggagcata agcttcgcta ttgagccaaa gctcatgttg atcgattgac tgagaagcat
     4681 ctcccgtcaa gttgaagtaa acatgatttg tcggattgaa taaagtatct tggtcactgg
     4741 tgccgcgaga ggtcactcgc cagatattat cttttgtcaa agtatagcgg atttccacat
     4801 ccattgtacc tggaaaacca tgttctccgt cgggacttgt agtagtaaaa atgacagaag
     4861 cttcattttc gccattcaaa atgacataag accatttttt taattcaaat ccaggagcac
     4921 caccatgcag attatgtcca gtttttggat ctgtggctaa ttggtaagtt tttccattga
     4981 gagaaaagcg gccattttcg attctccctg cggtgcgacc gatagaagca ccgatatacg
     5041 gatctttttc gatatattct tcagcggtgt caaatcccaa aactaattct cgatcatttg
     5101 attttaaact gacgattcta gcacctaaat cagagataga aagtgctagc ttgtttttgt
     5161 tctccaaggt tatcaagtga taaccttggc caaaatcttt ttctgtaatc ttcattttca
     5221 agatcctttc ttaatgggaa ggaactactg catcgtgaag ttcatcttcc attgtatcag
     5281 ctggagccaa tttgttttcc aattcctcaa cgatttgtgc atgttttttc tctgtcaatg
     5341 taatcttcca agcaaaaata atagcggaga aaatcatcaa agcagcagga gcatagaatg
     5401 cataagcttt gaaagtcgtt acgccatgag cagtgatatc agcagcagta gcattaccag
     5461 tcatcccaga agcgatagcg acaaacccta cgatcccgtt agacaaagca ccagcgattt
     5521 tatctagtaa agggcgaatt gatagagtaa cagcttcgtt acggatacca tttttccatt
     5581 gaccatattc aacagagtct gtgatcgtca tcaaagcgga taagaaaatc aattgttgag
     5641 ggaagtagaa caatactagc ccgatgataa cgattggcaa acttgaacct gcgatcgtaa
     5701 agaaaaagta agaagaaatc atcattgcga tccctccaag gtaaacgtag cgacgagaga
     5761 tgacgcgtgt aagcattggg aatagtggaa cagctactaa accaagtaag gcagcaacta
     5821 gaccaacgat ccaaaattca gttggttggc caagtacata tttgaagaag tagaataata
     5881 cggcagttgt tgctacattg gcaatcgcat aagcgatata agcaagggca agccacatca
     5941 actgatcatt ttgagcaact gctttgaaca catctttgat cccagctttt tcattttgct
     6001 gacggatcgc agtatcgact tcttttgtgc ccaaggcagt gataatcgca gtaccgcctg
     6061 aaataacagc agcaatcaca ccgaaccaga accagcctga agcgccttca atatgtttat
     6121 gagtaacaag ataggtaaag aaagtaacga tagggacaac gactagagta gtaccatttg
     6181 cacctagaga agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc tttgtttccg
     6241 tactcaaagc tggaatcatt gaccaaaaag cgatatcctt aaatgaataa aaactatcca
     6301 ataagatgaa aacgattgca aataatatga taaataaagt cgtattatga gtagctaagc
     6361 caaagaaatt ggtaaagatt gctaccaaga gtacggaact aacaacgccg ccgataacta
     6421 accatggttt gaatttaccg tattttgtac gagtattatc gatgatgcca ccaatcaaag
     6481 gatcaaaaat aatttcaact aagcggatac ctacaactaa gcttgtaact gtagcaatca
     6541 tttttgcatt cgttgcctta tctgttcctg cgaacatctg gcttgtcacg aataccataa
     6601 aataagtgct taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa gcgtaggaca
     6661 cacgttggat cattttgctt ttcataatct gtattcctct cctgttcaat atataatact
     6721 aagtaaaccg gttacaacga ataacaaaga tcttttaatg acttaaactt aacaagaaat
     6781 cgcttccttt ttaatatatt tctgtgactt ttatttaact ttttgttgca ttatactaaa
     6841 ggagtaagga gggatagacg tggagcaatc gattttttta aaaaaggaac atcaacaagt
     6901 agaaaaagaa ttgtattttg atttttgtgg tttctctaaa acgatgccgt ttcattcttt
     6961 tggtcctgct attcgcaatg attacatcct gcatgtcgtg atggaaggca aaggatctta
     7021 tcatgtgaaa aatcaacaat tccaattgaa aaaaggtgat ctgttcttga ttcgtccagg
     7081 agactcgacg ttttacttat cagatggaga agatccgtgg atgtattgct ggctttcatt
     7141 tggtgggagt gctgcagaag aaatcattcg gcagtcgctt ttcagagaag accaatacac
     7201 gatggtctct tctgacatac aaaaatatat cgacattatt ttagaatgca tgaaagatac
     7261 ggaagaaacc ttggaaaatg aattacagtt aacagcatta acctaccgtt ttttatcagt
     7321 ccttttaaaa gatggcggaa aggtcagcgg tggtgtacaa aaggttcatt cctctttagc
     7381 tgttgaaaca gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg ttgaggaaat
     7441 cgcccagcat ttagcggtca atcggagcca tttgtcgcga gtattcaaaa atcatatggg
     7501 taccagtatc aaggaatatt tgatcggggt acggatcaat cgaggggcgt ttcttctttc
     7561 tctgacggat gaatccgtgg aaagtattgc ctatcaagta gggttcaata gtctagtcgt
     7621 atttagccga atgttcaaaa agagtaccgg agaaacggct acgaactatc gtaaacgtat
     7681 gaaaaacgaa aattttaaga atattgcttt ggataccttg aaaaaacagt tggaaaaaca
     7741 aaccgcagtt tcttggacaa cctgattagt ctggttaaaa tgacaagcat cggcaaaaga
     7801 aacttgtggc ggttatgcta cactgtaaag cgaagactaa aaaggaggaa aagggatgcg
     7861 tacacttatc atcattagcc atccaacgat cgaagaatct ttaaatcagc aatttttcaa
     7921 agaagcttct gctggtttac cagctacttg gcatcatttg gaatcaagtt atccagacgg
     7981 aaaaatagat atagagactg aactacagct cttggcccag catgatcgga tcattttcca
     8041 gtttccgttt tactggtata gttctcctgc tcatttaaaa atttggcaag ataatgtctt
     8101 ggaacgagca gcacatgtat taaaagggaa agaactagga atcgtattga caacaggtgt
     8161 ggcggaaaaa gaataccaag ctggaggaaa agaagaatat acgatttccg aatttttgag
     8221 gccgtatcag cgaatcgcaa ataaattcca tatgacctat cttccgccat tcgttttagc
     8281 acaatttatg tatttatccc aggaaaaacg ttgggagaag ctaattgctt atcagcagta
     8341 tctctcattg gaaggcaaac catcgctgac tcagcggatt gactggttta ttcaaagagt
     8401 acaggaaaat cagaaaatgc aggaagaaga atctgaaaaa caagcatata tcgtagaagc
     8461 actgactgag gcaaaagagc agatcgaaga cttgaccttt acactgcaag aaatgaaagg
     8521 aacttcatta tgacaaatga ttggctgatc caacaattag atgaattaag cgaaaaatca
     8581 gaatatcaag accgtgcgct cttatatgaa ataaagaaac tgatggctga gatagacgaa
     8641 cgaacaatgc agctgcaagg agaaatcgac ggacaatctt ggaatcatct caactggtga
     8701 aattttctta taaataacaa agataaaaat gtgcacagcg acaattattt gctacaataa
     8761 gaatatgaag cgtttgataa cgctattata cataaaaatt ggtggtgaaa aaaatgtatg
     8821 atgaaaatga gtggggagaa aatgttcgga tgacccgaag aagacagcaa aaacaggcag
     8881 ctcgtaagcg gatgatcatg attggggcag cagttgccgt gtttttgatc atagcaggag
     8941 gagttgcggg tctatatttt catggaaaaa attcgtcaga agcgaaaagt acgaccataa
     9001 cggaaacaac gacaaagaaa acagagacga aacaaacaag tgagtcatca actaaaacaa
     9061 aagagacaca aacttctgaa gaaaaaacag caaatggttt gccagagcaa cttcaagcaa
     9121 tcgtaaatga ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt gaagaatacc
     9181 agacagaaat tcagggaaat caagagggaa tagctggttt atcagcagtt gctaaccaaa
     9241 aagcacgtga gcttcaagca atctccgacg aagggatcag aaaattacgt gcagcgtatc
     9301 aggcagcaga aaataaagac ggtgtagact tagatacttt gatcaatcaa ttatcggcta
     9361 attatacgaa tcatgtcgct aagatttccg atatttattt gcagactagc gcctctcttc
     9421 aagcagagtc aacaagcaca caagacacaa catcttctga ttctgagaca gcagagtcgg
     9481 tagaagcttc tgaaatgcaa gctcgaacaa cacaagacac aacagattcc tctgaaacta
     9541 ataccaacag cgcgacttca caggctgcga caaccgtagt tttggaagga gaaggtccaa
     9601 atcaaatagc cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg aatgggatga
     9661 gcatggagaa ttatttcctg actcccggtg agacgctaaa attgaattga taaaagcaat
     9721 aaaaaagaac gaagcttcca ctaaggtgaa gcttcgttct ttttttattt tccggttctt
     9781 ttttcgcgta caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc aataatcaat
     9841 gagattctcg tttcaggatt gataaacatg aaaatcaata cgatagctaa aaaagcaagt
     9901 gtcacataat tcgtataagg agatagtggc attttaaaag gatgatcatg cattttatct
     9961 gcgtgcttct ttttgaagcg aatctcgctg atcaaaatca ctacccaagg aaccatacca
    10021 ggcaaaatac ttgagctgta tacgaaaacg aaaatatttt ctgactggtt gatgaacatt
    10081 ggtagaagat aatttaagat cagaccaatt aagattccac ctgagattgc tacgacagga
    10141 taaaaaggcg caccgtgacg agatagtttc agaaattttt tagacatctt tccatttatg
    10201 gcaagtgtat agaccatacg acttgcgctg aaaatccctg aattgcaacc tgataatgcc
    10261 gctgtaatca cgacaaaatt aatcagtcct gcagcaaatg taatgccgac tttagaaaaa
    10321 gtttgtacaa aaggtgaacc aatctcactc aattgattcc acggatagat actcacaatg
    10381 ataaaaatag caccaatata aaaaatcaag attcgaccga tagtggactg gacagcttca
    10441 atgatcgtct ttttaggatt ctctgcttca ccagcagtca ttccgatcag ttcgattcct
    10501 tgataggaag caacaacgat cgataatgca aagaaaaatc ctttgacgcc tccagtgaag
    10561 aatccaccat ttttccaaag atttgaaatc cctactgcct gaccatgatt accaaatcca
    10621 aataagatta ccccaagacc tgcaatgatc atcaaaatga tcgttatgac tttgatgatc
    10681 gaaaaccaaa attctaattc gccaaacgcc ttgacagaaa taagatttgc cagcataaga
    10741 aacaagacga caatgattcc gggaataatt gccggcaaat caggccacca ataattcata
    10801 taagatccta cagcaatcac ttcacttatt cctacgacaa tatattgaaa aatattactc
    10861 caagcggtca agtagccagc cacaggatgg atgtactcgc tcgcgtaatt tgcaaaagaa
    10921 ccagtcgaag gatcaacgta aagcatttcg cctaaagcac gcataatcaa atacaaaaag
    10981 aatcctgcaa tcgcataggc tcccatcact gagggccctg tccaacgtat ggttgaggag
    11041 gcacccataa acagaccgac accgatcgtt ccacctagtg cgatcatttg gatatgacgg
    11101 gcactaagac ttcgagttaa cttttcttct tccatacaaa aactcctttc gttgttgagt
    11161 caacaagaaa aaataatcaa acgtttcaac acatgttttt cattattagg ttagccttat
    11221 tgaactcttg atgtgattct acagaaaatt ttcataaaat gcgaggaaaa ttcgaaaaaa
    11281 actttttcat cattctactt gaaaatgctt tccattttag ttaaactata tttaaataaa
    11341 aagttaggta aacctaaaaa ggagtgtaag atttggaacg tacggccatt gtaattcaag
    11401 acctttcagc cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg acgataaatc
    11461 cacaaaaaat taccggtatt atcggaccaa acggtgcagg aaaatcaaca tttatgaaat
    11521 ctttgctaga gttgatacca gctactactg gtaaagtcac cttttctgga cagccggtaa
    11581 actcagtccg taaaaaaata gcctacgtgg aacagcgaag tgaattggat ctttcctttc
    11641 caattgatgt attaggcgtt gtacttttag gaacatatcc atctttacga attggacaaa
    11701 gacctgggaa aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta gggatggaag
    11761 aatatgccaa aagacagatc agcgaactat cgggtggaca gcttcagaga gtttttattg
    11821 caagagctct agcccaagga gcagaatgga tctttttaga tgaaccattc gtagggattg
    11881 atgcgttaag tgaacgaaag atctttgaca tcttgcagga attgaagaat tcaggaaaaa
    11941 cgattttgat cgtccatcat gatcttcata aagtagaaga atatttcgat gaggttattc
    12001 ttttaaataa acagctgatc gcttccggtc cagtacaaga agtctttaca tcgaagaacc
    12061 ttcaattggc ctatggtgag atcatcagac atttagtaaa aggaggagag aaaaaatgat
    12121 ccaatccttt attgatggat taatgaatta tcaattcctg caatacgctt tggtcacttc
    12181 catgcttgta ggacttgctt ctggagtcat cggttctttt attattttac gagggatgtc
    12241 tttgatggga gacgctatct ctcacgcagt tcttccaggt gtagccattt cttatatgtt
    12301 tggttttagt tacatctttg gagccactgc ttttgggatg ctaacagcag cagtgattgg
    12361 tttcgtgact cagcggagcc gattgaaaaa tgatacagcg attggaattg tctttagctc
    12421 cttttttgca ttagggatta tcttgatttc atatgcccag agtgcgacag atttgtatca
    12481 tattttattt gggaatgtct tagctgttag ggaaagcgat ttgttgctga cagcactcgt
    12541 tagtggaatc gtcttgatat ttgtcttttt cttttataaa gaattgaaga tcacatcatt
    12601 cgatccgaca atggcaaaag cttatgggct gaacacatcg ctgatccatt atcttttgat
    12661 gttctttttg acattagtgg ctgtagtcag tttacagaca gtaggaacaa tcttggtgat
    12721 tgccatgttg atcacaccag ccgccacggc ttacttgcta acgaaccatt tactgaaaat
    12781 gatcattaca gctgcaggaa tcggtatgct aagtgcagtt gtcggtgtgt ttttcagtta
    12841 tagttacaat tggccatcag gagctacgat cgtgttagca tgtaccgcat tttttatcct
    12901 tgctttttta ttttctccaa caaaaggaat tttatttcag aaaggaagca gatagatgaa
    12961 aacaaaaaaa tcactctttt taatcttggc agttagtttc ttggtattag ccggttgcgg
    13021 aaagcaggct tctgaccaag cggatgaagg aagtaaagaa aagttgtcag tcgtggctac
    13081 caattcgatc ttggcggaca tggcaaaaga ggtcggaaca gatcaaatag atatccacag
    13141 tatcgtacca gtcggaacag atccgcatga atatgaagta ctaccagaag acatcaaaaa
    13201 ggcaagcgat gcagatgtta ttttatacaa cggtttgaat cttgaaacag gtaacagctg
    13261 gttcgataac ttgatggaaa cggctaaaaa agaagaagga aaagattatt ttgcagttag
    13321 caaaaatgta gaacctcttt atttaactag cggtgaagaa catacaaaag cagatcccca
    13381 tgcttggcta gacctatcta acggaataaa atatgtggag gaaatcgcac gtatattctc
    13441 tgaaaaagat gcagaaaatg cgacactcta taaaaaaaat gcagaagcat atgtggaaaa
    13501 actaaaagaa ttagatacac aagcgaagga aagttttgct tctatcgaag agaacaaaaa
    13561 attattagta acaagtgaag gggcattcaa gtatttttca cgagcatatg atttgccagc
    13621 agcttatata tgggagatca atacagaaag tcaaggtacg cctgatcaaa tgaaagcgat
    13681 cattgatcag ataagagcaa aagaagtacc ggttttattc gtggaaacca gtgtagactc
    13741 aagaagcatg gaacgggtag caaaagaaac gggtttgaaa atctatgata aactgttcac
    13801 tgattccata gcaaaagaag gagaacaagg agattcttac tatcagatga tgaaatggaa
    13861 tattgaaacg atccatgaag gtttgtcaca aacaaaagaa agctgaaaag tgcaaggtct
    13921 agcttgagga gcagaccttg cattttttat aagagatatg aaaaaaaatt atgctgtttt
    13981 tcgtcgtaca gatacctttt ttgaagaaat tccgttatag ttagagtaag gaaggaaggt
    14041 gtggctatga attttacacg taaagataaa tatacgatta aagaagaagt ctttcgattg
    14101 atcagccagc aggaaaatac cgacaaggat caagaccttc aatttcttga agcagaatta
    14161 gctaaattat tcatagcaaa tcaaaatgag acaacagaac cagatgaaga gctgtacata
    14221 ggcaaatggt tgtttgatga atttcagcct ttagatgaaa ataccggtat cggttatttt
    14281 gtgttccttt ctccagtcgg cttcacacct ggcgtattag ttaaacaaaa cgacgaaata
    14341 accgtcaaag catggcctgc attattttca gtcatcaaag cagaaggagt aatcaaaaag
    14401 atccagtcgg cctattataa aagtcaattt attgccaaca gcaaattaat gaatatgttt
    14461 tataatcgtc tagtagaaat tgctaggcct gggaaaatcc cgcaaacatt cacgtacaca
    14521 cagcaaaaaa atctctatga agaagtattg tattcccgcg atctgtctga gttttcgcca
    14581 tgggaagagg taaggctcca tgaactgtta agtacaaaac cagtttcatt gaattttttt
    14641 aatgcattag ataacaaaag aaaattaatt tcaacaaatt attgggaagt atttgctgca
    14701 agaaaaaaat ggatggaaga aaagaagatt gccgatcagc agatccagtt tgtccagctg
    14761 aaaaaagaaa aactatatta tgggttatac agccgttaac agcaagcgag gaagaccatg
    14821 acattaaaag aagaaatcat acaagaaagc aaacgattag gaattgacaa aatcgggttc
    14881 accacggcgg aaccttttga ttcattaaaa gaatcgttgg aagaacaaaa agcagctggc
    14941 catacttctg gctttgaaca tccaaatatc gatgagcgtc tttatccaga aatgacattt
    15001 gatcagccga aatcgatcat ttccattgca cttgcgtatc ctactaggat ccatgaagaa
    15061 gtgcctaggg atgaaaaacg cgggcagttt gctcgtgctt cttgggggat cgattaccat
    15121 gatatactca gagaccgttt gaaccgattg atcgaattca tccaaacaag agcagaaaaa
    15181 tggcaaaaag aagaggaatg gcgtctagct ccgcaagtag atactggaga actgatcgat
    15241 gtcgctgtag cacagcgagc tggtttagga tttattggac gaaacggatt gttgatcact
    15301 gaagagttcg gttcatttgt ctatcttggt gagatcgtta ctaatattgt atttgagcct
    15361 gataaaccag gagaatttgg ttgcggtgac tgtatgcgct gcgtgactgc ttgtccgaca
    15421 aaagcattgc ttggtgacgg aagaatgaat gcccagcgat gtttgtctta tcaaactcag
    15481 acaaaaggga tgatgccgga agaatatcgt aaaaaaatgc gaaatgtcat ttatggatgt
    15541 gatatctgcc agttagtctg cccttacaat caaggaaaag attttcattt tcatgaagag
    15601 atggaaccaa aagtagacga agtatatcca aaattaaagc caatgctttc gatgtctaat
    15661 aaagacttca aacagcaatt tgggcattta gctggttcat ggcgtgggaa gaaacctttg
    15721 cagagaaacg cattgattgc tttagctaat ctaggtgatc gaacggcatt gcctgagatt
    15781 tcagaatgtt taacagatgt ccgccctgtc atcagaggaa cagcagcttg ggctattgga
    15841 cgtctaggaa caaaagaacc ggaaaaatgg cttgatgtat tagatgaaat attagctaaa
    15901 gaaacagaag aagtcgttat aaacgaattg gaacatgccc agaaattatt gcggagaaag
    15961 ttaaaataaa aaaatagtta acattattca aagtttttgt ccagtaattg ttgtaacaat
    16021 tactggtttt tttgtatttt ttacattttt ttaagagaat ttgataaaaa tcaaaaattt
    16081 ttttgctttt ttttatggat tattgcagtg aatgttacag aatctgcgtt tttcattcaa
    16141 aaataaaaaa acatag
//
LOCUS       DARBDN010000059        15951 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000059 DARBDN010000000
VERSION     DARBDN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.059"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(387..809)
                     /locus_tag="SCH06_001860"
     CDS             complement(387..809)
                     /locus_tag="SCH06_001860"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEG1078416.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            complement(823..2229)
                     /gene="atpD"
                     /locus_tag="SCH06_001861"
     CDS             complement(823..2229)
                     /gene="atpD"
                     /locus_tag="SCH06_001861"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEG1078417.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            complement(2252..3154)
                     /locus_tag="SCH06_001862"
     CDS             complement(2252..3154)
                     /locus_tag="SCH06_001862"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEG1078418.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            complement(3168..4724)
                     /locus_tag="SCH06_001863"
     CDS             complement(3168..4724)
                     /locus_tag="SCH06_001863"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEG1078419.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            complement(4747..5289)
                     /locus_tag="SCH06_001864"
     CDS             complement(4747..5289)
                     /locus_tag="SCH06_001864"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEG1078420.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            complement(5276..5800)
                     /gene="atpF"
                     /locus_tag="SCH06_001865"
     CDS             complement(5276..5800)
                     /gene="atpF"
                     /locus_tag="SCH06_001865"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEG1078421.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            complement(5891..6106)
                     /gene="atpE"
                     /locus_tag="SCH06_001866"
     CDS             complement(5891..6106)
                     /gene="atpE"
                     /locus_tag="SCH06_001866"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HEG1078422.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            complement(6159..6878)
                     /gene="atpB"
                     /locus_tag="SCH06_001867"
     CDS             complement(6159..6878)
                     /gene="atpB"
                     /locus_tag="SCH06_001867"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEG1078423.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            complement(7180..10023)
                     /gene="rnr"
                     /locus_tag="SCH06_001868"
                     /pseudo
     CDS             complement(7180..10023)
                     /gene="rnr"
                     /locus_tag="SCH06_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418328.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
     gene            complement(10026..10781)
                     /locus_tag="SCH06_001869"
     CDS             complement(10026..10781)
                     /locus_tag="SCH06_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEG1078424.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            complement(10884..11120)
                     /gene="secG"
                     /locus_tag="SCH06_001870"
     CDS             complement(10884..11120)
                     /gene="secG"
                     /locus_tag="SCH06_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEG1078425.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            complement(11238..11516)
                     /locus_tag="SCH06_001871"
     CDS             complement(11238..11516)
                     /locus_tag="SCH06_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEG1078426.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            complement(11629..12597)
                     /locus_tag="SCH06_001872"
     CDS             complement(11629..12597)
                     /locus_tag="SCH06_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078427.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     regulatory      12812..12856
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            12880..13854
                     /locus_tag="SCH06_001873"
     CDS             12880..13854
                     /locus_tag="SCH06_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HEG1078428.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     gene            13859..14434
                     /locus_tag="SCH06_001874"
     CDS             13859..14434
                     /locus_tag="SCH06_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEG1078429.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(14501..15640)
                     /locus_tag="SCH06_001875"
     CDS             complement(14501..15640)
                     /locus_tag="SCH06_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HEG1078430.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT         4357 a         3443 c         2856 g         5295 t
ORIGIN      
        1 ctgagccaga atgtggttca ttctgactca gatttgattt tgcacaactc atcagtcctt
       61 attgacaaag agcccaaaag tcttgtcgca gtcccttatt ccaaataaac ggtgttcaat
      121 catctgaccc tcggtattag ctcaaaaaac ggcaaaatat gaggaactat tttccatttg
      181 tttctctaat actcaggaca aaacgctgat ttcacaacct ccgatatacg gtgttccaga
      241 agtagcttct tcgaaaaata agctgagatt tcacaaaaat ttgagaagca attttcgtaa
      301 attccttctt atgtcttgaa gctgaccact tctgtcataa cctcttttta ctgttcttaa
      361 acacggataa acatccgcat ctcattttat gagtgcttag atactttgat acgattgatt
      421 gctcggtgca acgcaacagt tgcccgtttc aattcgttcg tatcttgttt tgcttttgct
      481 tcttcgattt ggcgttctgc gcgttgtttt gcacgttccg cacgagatac atcgatatca
      541 cgttcacgtt ccgcactatc agcaacgatt gaaacaacat tatcacgaac ttccatgatt
      601 ccgccattaa cagcgatcca atcgacgtgg gtatctgaat ctgttcgttt tacacgaact
      661 tcatcaatcg tcaatggaac gatgattggt gcatgtttag gcaaaatccc aagctcacca
      721 gctgtcgtac gtgcaacgac gatagctgca tggtgatcat agaccaaacc ggcaggagtt
      781 accacattta ctgttaaata ttgatccatg gggcacccct ttctagtagc ctagtgtttt
      841 cgctttttct acgacgtctt cgattcggcc aacacttcgg aaagcttctt caggaagatc
      901 atcgtatttg ccttccaaga tttcgcggaa tcctttcact gtttcttcta cagggacata
      961 tgaacctgga agaccagtaa attgttcagc cacgttaaag ttttgtgaca agaagaattg
     1021 gactctgcgg gcacgagaaa ctaacacttt ttcttgatcg gataattcat ccatacctaa
     1081 gatagcaatg atatcttgta attcacgata tcgttgcaat acgtgttgga cttctgttgc
     1141 tactttataa tgttcttctc ccacgatttc aggtgctaaa gcacttgaag aagaagccaa
     1201 tggatctacc gctggataaa tcccttgttc tgttaattta cgttccaagt tggttgtcgc
     1261 atccaaatgg gcgaatgctg ttgccggcgc cgggtcagtg tagtcatcgg ctggcacata
     1321 gattgcttgg atcgatgtga tcgaaccttt tttcgtagat gtgatacgtt cttgcaattg
     1381 acccatttct gttgccaatg ttggttgata accaaccgca gaaggcatcc gtcctaacaa
     1441 ggctgatact tcagatccag cttgagtgaa acggaaaatg ttgtcgataa acaacagtac
     1501 atcttgacct tctacatcac ggaaatattc cgcaatcgtc aaaccagtca aagcaacacg
     1561 catacgtgca cctggtggtt cgttcatttg tccgaacacc atggctgttt tttcgataac
     1621 tcctgaatct ttcatttcat aatacaagtc attaccttca cgagtacgtt cacctacacc
     1681 ggtaaataca gaaataccac catgttcttg ggcgatatta tggatcagtt cttggatcag
     1741 tacggtttta ccaacaccgg caccaccgaa tagtccgact ttcccacctt ttaaatatgg
     1801 ggcaagcaaa tcgataactt tgatccctgt ttccaaaatt tctgtacttg tacttaattc
     1861 gtcaaaggct ggtgcttttt tatgaatttc gcttctttcc gcatcttctg ggaaaggtgt
     1921 ttctaaatcg atcgtatctc ctagtacgtt gaatacgcga cctaatgttt ctttacctac
     1981 aggaacagag attgctttgc ctgtatcaat gacttccatt cctctttgta aaccatctgt
     2041 tgattccatc gcaatggtcc ggatcactcc gtcccctaat tctaacgctg cttcaagaac
     2101 aacttttgat ttattttcgt catttttata aacaactaat gcgttgttga tatctggtaa
     2161 ggattggtct aaagaaaatt ccacgtcgac aacgggaccg attacttgaa caatcttgcc
     2221 tgaactcatc ttttttcctc caatctcaat actattctag tgccgaagct ccggcaacaa
     2281 tttcggtaat ttcttgggta atagcccctt gtcttgcacg gttgtaagaa accgtcagct
     2341 catcaatgat attagcagca ttatcagttg ctgttttcat tgctgtcata ccagcagcat
     2401 gttctgctgt tttggcgtca acgatcgcac cgtagatcaa actttcagca tactgaggca
     2461 ataactgaga caagatttct tcttttgaag gttcaaaaat atattcttgt tcgaaagtag
     2521 ttgcttcttc tggatctaag tctgagattg gcagcatttt ttctacacga aactgactag
     2581 ttagcgaatt gatatgatgg ttataacata cgtataattc atcgaatact tcgttttggt
     2641 acatagttgt tgccatattt acgattttgc ggacttcatc aaagcttggc tgatcagata
     2701 gattgcgcag ctcatatgct agattgatac cgcgtgcttt aaagaagtct gcaccagttc
     2761 cgccaattgc gatcatcacg taatcatcgg gtgattggtg gtcttcttct aaaatagaca
     2821 tcgtttgttt caatatcgag ctgttatatc caccgactaa accgccatct gcagtgatga
     2881 cgatataacc cgttttctta acaggacggc tgagcaacat gctgttgtaa ttgatatccc
     2941 ctctaggatt ttctgaggca atatcattta actgagtagc agtcaaatgc gtaacgattt
     3001 ctcttacttt tgttgcataa acctgaaact tctgtgaaga agcttcagat tttgtcaact
     3061 tagaagcaga caccatctgc attgcccgcg tgatttggct cgtttttttc gttgaagcga
     3121 tacgtgtctt gatttcattt aatgaagcac ccattcatct cacctcacta tgcattttga
     3181 atggatttca atttatcttc tgtagaggaa ttatttcctt ttgtagctaa gaacatgtct
     3241 ttatattcct gaatcgcact gttcaacgct tcttcttctg gaagatcttt tgttgtacgg
     3301 attgtttcaa agatatctga atgattggta tccagatatt cgaataattc atgttcgaag
     3361 tctaaaatac tgtctacagg gatactatct aagaatccat gtgtcaaagc atacaaaatc
     3421 actacttgtt tttcaacagc tagcggtgca tgcaattttt gtttcaagat ttctactgta
     3481 cggcgtccac gatttagttt tgcttgtgtt gctgcatcca agtcagaacc gaattgtgta
     3541 aatgcttcta attcacggta acttgctaag tctagacgta aagtcccagc aacttttttc
     3601 attgctttga tttgcgcaga accccctaca cgagatacag atagtccggc atcaaccgct
     3661 ggacgagtac ctgcgtagaa caagtcgctt tctaagaaga tttgtccatc agtgatcgaa
     3721 ataacgtttg ttgggatata agcagagata tctccagctt gtgtttcaac aaatggtaag
     3781 gcagtcattg aaccgccacc taaatcatca cttaattttg ctgcacgttc caataagcgt
     3841 gagtgtaagt agaaaacatc ccctggataa gcttcacgac ctggtggacg gcgaagcagc
     3901 aaggaaagtt cacgataagc aacagcttgt tttgaaagat catcaaaaat gatcaagaca
     3961 tgtttcccgt tgtacatgaa ctcttcaccc attgcagtac cagcatatgg tgcgatataa
     4021 agcaacggcg ctggttgaga cgcaccggca ttcacaacga ttgtgtaatc cattgcgcca
     4081 tattttttca atgtttcaac ttgtgtacga actgtagaat ctttttgtcc gattgctaca
     4141 tagatacaga tcatatcttg acctttttgg ttgatgatcg tatcgatcgc aatggaagtt
     4201 ttccctgttt tacggtcacc gataactaat tcacgttggc cgcgtccgat tggtacaaga
     4261 gcgtcgattg cttttagacc tgtttgcatt ggttcgttaa cagatttacg ttgcataacg
     4321 cctggtgcca ttgcttctac tggacgagct ttgtcagtaa cgatttcacc tagtccgtca
     4381 attggctgac ctagcggatt aactacccgt ccaatcaagg cctctccaac tggaacttcc
     4441 atgatctttc ctgttcgttt tactttatct ccttcacgaa tggactcgaa atcgccaagg
     4501 ataatgatac ctacatcatt tgattctaag ttttgcgcca ttccgtatga gccatttgaa
     4561 aattcaagca actcaccact catcgcgttt tctaaaccat gtgcacgagc gatcccgtca
     4621 cctacataag ttacggtacc gatttcttcg actgaaagca cgttttgata attttcaatt
     4681 tgttctttaa tcaaggcact aatttcttct gctttgatgg ccattcgatt cacctacctc
     4741 tttgtactat ctatttaatt gattacgcat attttctaat tgcgtgcgaa tgcttccgtc
     4801 gattactcga tggttagctt caacaatcgc gccaccaata atagaagaat caacgatttg
     4861 ttttaattcg actgattgat agttcattgt ttttgcaaca ttcttttcta attgtattcg
     4921 ttgttcgtct gaaagtggaa ctgctgttgt gacacttccc aacagcaaac cttgatgttc
     4981 atcatatcga cgttcatatt cttcgatcat gaacaaaaga tcatccattc ggttatacgc
     5041 ataaacaact tctaaaaagt ttttaacgat tccatcatag ccactaacaa gcttgtccat
     5101 gatttctcgt ttttcatgag gttctagacg aacatcactt aacatattac ctaatccagg
     5161 tacttgttca tagatttgac gtaagcttac gagatcttga taaatttctt ctgctttatt
     5221 tgaatcgatc gccagttcaa ataaagcttt cccgtaacgt cttcctactg tatatttatc
     5281 tagtttcatt tgaagaacct agaccttcga tatattgatt gattaatgat tcgtgcattt
     5341 ctggagataa ttctttgttc aagatttttt ccgcgatttg aagagatagt tctgcaacat
     5401 cgtcttttac agagttcagc gctgaatcac gttctacagt gatatcagct tgggctttac
     5461 tttttagacg agctgcttct tcttgagcat ccttcaaaat attttggcgg cttaattctc
     5521 cactttcttt cgcatttttg atgatatcag ctgcatcaga acgagaggct aacaattgtt
     5581 gttcgcgttc ttgttccatt ttcgctgagt tgatgcgaga ttgttctgca gaatccaaat
     5641 cattggcgat cttgtcttca cgttttttca aaatatcgct gattggtccc caagcaaaat
     5701 gcttcaagag agccagtagt atcaaaaatg agccgctgac aacgatgaca tttcctaaca
     5761 tcgcattgcc aacttctgca attgccaatt gattcagcat aggcgagcct tcctttcttt
     5821 gaagtacttc tagttttcat gtaaaaaagc agtaacaaac caaattgttt ctgccttaat
     5881 actgattcaa ttaaacacca aaaactagaa tcaaggcgac aactacccct aagataggaa
     5941 cagcttcgac tagagctacc ccgataaaca ttgttgtacg gaattgacca gacatttcag
     6001 gttggcgagc cattgattcg attgttttag agataacttg accgttacca taaccggctc
     6061 cgattgctgc tcccatgatt gcgattgctg ctgcgatata attcataatt gttttcctcc
     6121 taaattagat aaatagtagt ttgtttttaa aacgaatatt attcttccac ttcaatctta
     6181 tggctcatat aaaccataga taaagtaacg aagacaaatg cttggatgct tccgataaac
     6241 aaggagaatg cgatccagac catctctaat ggaattgcta acggcaatga gaaccagcct
     6301 aagcttatta ccatttttgc aatcaaggtt agcaaaactt cccccgcata aatattccca
     6361 taaagacgta aagcaagtgt taataagttt gtaaattctt caatcagttt catcggaaac
     6421 ataaaactat atggtttcaa gaacgaattt acgaaatatc ctttgaagcc taactttttc
     6481 accccaaata agtgagtaag taagatcatt ataaatgcca aagttaaagt aacaaacggg
     6541 tctgctgtcg ggcttttcca aagtgttgtt tcgttaggta aaacgatttt tgttactaaa
     6601 ccgatgttgt ttgcaacaaa aacaaataaa aacaatgtaa atgccaacaa atggaaattg
     6661 ctcaattctt ttctaggcag attatctgtt acgattcctc gactaaaatc aatgacccat
     6721 tctatcgcat tttgtttgcc tgttggtttc aacttaagat ttcttgtaaa aaagtaagct
     6781 aagaagaaaa caatcaaaca ggtcagtaac accattatac aaactgtacc atcaaaccaa
     6841 attggtccaa tgtggaacgt tagcgagcgt tcatccaatc catttcacct cttttccccg
     6901 aaattcacat aaaatcaatt catgtgcgta tctggttttt tccaatcggt ttctaaccac
     6961 acggtatcat accaccatga aacagaaaat tcaaaacatt ttcatgaaaa ttagacactt
     7021 ttttatttca gtcaaaaacg aagcgaattt ttctttatac acggtgctcc tgatctaaga
     7081 aaaaacctat gataatcatg ttttatcaga ttaaatgcta acaaatttta tcattaagta
     7141 aaagcaaaag caccgaatat gcgaaaaagg ataatgaaat tatctagaga aattttttaa
     7201 tgttcgatca atttgtcgat cgatatcttt tcgtttcaaa tcttcccgtt tatcataaga
     7261 ttttttccct ttcgccagac caatcaatac cttggcatag ccgttacgaa tatagacttt
     7321 taaaggaaca acagtgattc cagtattttt caattcattt tcaagccgga tgatttgttt
     7381 tttgtgtaat aataactttc tcgtgcgcaa cggatcatga ttaaaaatat ttccttgttc
     7441 ataaggactg atatgaacat tatgcaagaa agcttctccg ttgcggacgc gaataaatcc
     7501 atcttttaga ttgatccggc tgtttcgtat cgacttgatc tcggttcctt gcaagaccat
     7561 ccctgcttcc atcgtgtcga tgatcgaata atcatggcga gctttcttgt tttgtgcaat
     7621 taattttccc tcgccttttg gcatagctgt ttcctccaac tcattttatt ttttcttttt
     7681 cttcttttta acacctttgt aaaatggctt cttccctttt ttcttaccga acgtttgctt
     7741 actatcgcta tatcgtttgt tcttcttgcc atttctttct gggcgttttc ctgcttgttt
     7801 tccttcgcgt tttcctgatt ttccatttcg tgtttttggc cgttccaacg ctgtaacctc
     7861 ttctgcggaa acaagttcaa aatctactgc tcgttcatct ggatcagctt tgactacttt
     7921 tactcgcact ttctgtccga ttttaaaagt cagaccagtt ctttcaccta caagagctaa
     7981 atgattttca acaaaatgga agtagtcctg tttcaattca ttgatatgga tcaatccctc
     8041 tactgtattc ggcagttcga taaacaggcc gaatttcaca acagagctga tgatcccatc
     8101 gaattcttcc cccactttgt ccatcatgaa ttctgctttc ttcatggaat ctacttcacg
     8161 ttctgtttct actgcacgac gttccatctt agaactatga tctgcaattt caggaagttc
     8221 cgtagcccac gaactttgat tgctttcact tttatcttca ctgtaagaac ggatcagacg
     8281 atggacgatt agatcgggat agcgtcgaat aggagatgta aagtgtgtgt agtaatctgc
     8341 cgctaagcca taatgcccaa aattgtcttc tgaatagcgt gcttgttgca tgcttcttag
     8401 caacatagta ttgataactg cagcttctgg tttgtcttct actccttcga tcacatgctg
     8461 taaatctttt ggtgtgatcg ttcctttcgt tcctcggacc agaatgccca aagctgaagc
     8521 aaaatcaaag aagcgctgca ttttttcttc ttttggctgt tcatggattc ggtaaataaa
     8581 cggcagattt aatttattat aatgttcagc taccgtttca ttggccgcaa gcatgaaaga
     8641 ttcgatcaag cgttcaccaa ttcctctgct tcttagctgg atatcatttg ggtgtccttc
     8701 agcatcaaca aggatttttg cttcgcgatc ctcaaaagaa atcgcgccac gtttgattcg
     8761 catcgtttca aggattcgat gcaattcacc catttcttgg aacataggta cgagctgagc
     8821 atagcgttgc atcgtttctt cgtcttgatc ttctaagatt tgattgacag ctgtgtaggt
     8881 catccgttct gttgtttgga tcacacttgg gaaaatatca tgagagacta cttgtccatt
     8941 tggatcaatc tccatttcgc aactcatggt cagccttgga acatggggat tcagtgaaca
     9001 gataccattc gataaacgtt gcgggatcat cggaatcact cgatcagtca aatatacact
     9061 tgtccctctt tcatatgctt ctctgtccaa ttgactgcct tgtgtcacat agtaagaaac
     9121 atctgcaatg tgtactccaa gaaaataatt accgttatct aattttttaa ccgtaactgc
     9181 atcatctaga tcttttgcat cttctccatc aatcgtaaca atgagctgat ttcttaaatc
     9241 tctacgtcca gttatatcct tttcgctgat ttgatctgga acttcatctg cttcagacaa
     9301 tacatcatca ggaaatttcg tagggatacc attagccacg acaattgaga ggatatccat
     9361 gccagggtca ttcttatgac caatcacttg cttgattatc ccttctaaac tagtcgcata
     9421 ccctttttca gggtaatggg tcagttcgat cagcacaata cttccgtcaa ctggacgaac
     9481 tccctctgct gctgcatata ctttaaattg gttgagcttt ctatctttcg ggataacaac
     9541 gccgtaaaga tccgtttctt gtatttcttc ttctgaataa gcaacgaatt cccctgctaa
     9601 ctgagtagtc gcccggtctc gaatctcgac tactttcccc tctgctccgc gatccatatc
     9661 tgtatttgct cgcttcatga tatcgattgc tacggtgtct ccatccattg caaaaccagt
     9721 cgcttctttt gggatataga tgtcatcttc ttcgggatca atcgttacaa atccaaatcc
     9781 tcgttcattt gctcgaaatg ttccttcgat caagattggt tttaaaggaa gtttcacttt
     9841 tcctttttta ttgaaaacta tactctgttc tctttccatt tgagcaatcg tttgtactag
     9901 taatttaaaa tcatcgcttt tttggaaccc taaaccttca gcgatttctt ccatagaaaa
     9961 actgcgtttg cgactgcttt ccatgaaaaa gagaattttc tcttttatcg tttcttttgt
    10021 catatttatt cctcattcca aggtaatttt tctaaaaatt ccaagacgtc tttttctaat
    10081 tcgcgtcttg ctgtaccaac tgtaatcaca tgaccacttt caggatacca tcgaagtgtc
    10141 actcgctgac ggctcaactt gcgtgcagtt tcaaatacgc cattagggtc gatcatttca
    10201 tctttcccag cttgagctaa aaatatcggc tgttggatat ctgacaacct actttctacg
    10261 attgctgcct gatcttgtat atccattaat tgttgttcag ctaacgagcg gtaagcaact
    10321 gctttttcat tgatttcttt ctctgattta cctgctgtct tcagcacttg acgtacgtat
    10381 ttttcaaagt tttcaggcac gtttgttttt acaggagaca aaggcgaaca gaaaaaaccg
    10441 ccgccaatca ctgattcttc ttctagtgct cgtacagcaa agatgccgcc cattgataat
    10501 cctaatacgg caatatcaga aaactgctca gactgtaaaa aatggatggc ttttttagtg
    10561 tctgcccacc agctttctgc tttttcttgc aaaatatcat atggctccat tgttccgtgt
    10621 cctttaaaaa gcggcgcata aactgtataa tctgcttttt ccaaaaatcg tgcgagcatt
    10681 cgaacatcgt ttggacttcc tgagtaagcg tgaagcagca aaaccgctcg ctttccatgt
    10741 tttgcataaa ggggttttgg taattgtctc actcgtctca cctctttcgc ctcattttac
    10801 catagtttct ttcataactt cttcttaagc gttctctttg caataaaaaa agccgcccgc
    10861 cgttttgcga gaggcttatt caactacttc gaagataaat atgctaggac aaataataag
    10921 atcatccaga tagctcccat aactgcagtt gatcgctgca tgacagcttc aaagccgcga
    10981 gctttttgtt tgccgaatag ttgatccgca ccgccggtaa atgcactcgc tgcactattt
    11041 tgcttgcttg gctgcatcat aatcgcaatg accataacaa tcgataaaac gatcacgatt
    11101 cccaaaatta aattatacat atcgcagcct ccttcccaaa agatatcgtc tctttaactt
    11161 tatcatagat aaaagtccgt gacaactcta tataaatgga ataacagctg aaagttcaaa
    11221 actttcagct gttattctta tgactgacgt aagacgtctt gatattctgg tttcttttca
    11281 aactcttttt ttgcataagg gcataaagga atgatctttt tcccgtctcg tcttgctaat
    11341 tctactccag tatacactag cttttcagct aacttttgac cacgatatgc tggatctaca
    11401 aatgtatggt caatgatcat gatgtctggg cccgcatctg accatgtcat ttctccgatc
    11461 tcttgttgtt catcattgaa taaagcaaga cgattttttt cttctttgat ttccatatgc
    11521 cgcactcctc aaataactga tattttttta ttcctacctt attttagcag tctcctgatc
    11581 tataaacaat tatttatcct cgaattactt acaaaaaaga agagaaaatt aattcatcgt
    11641 tattctttgt tcaataaatg aaaaaatcac tgtccaatag gttttcggat ctttcatcga
    11701 tgcttccaag tgttctgctt ctggaacaag cagcagtgct ttatcccctg ccgtagcatt
    11761 ttgaatcgtg tacgctgctt ctgtagggac aaaatgatct ctttcaccat gaatgaccaa
    11821 taaaggcaga tggttgctgc caagctgtct cgtagctgat gcttgcttta aggagtaacc
    11881 ggcgtatttc tgggcataat gattcgcata tctcatgacc atttttttag gaaagacagt
    11941 gattttactt aacatatatc ggaattctgc ataaacagaa acatatccgc tgtctaaaat
    12001 aaatcctttg accgctgatg gaagtttttc accacttgcc atcatgatcg tagaagctcc
    12061 cattgatccg ccgtgtaaaa taatggacgc attcggctgt tcatctaaga tgagttggat
    12121 ccaggcaatt aaatctagcc gatctagcca tcccattccg atgatttctc cttcactttc
    12181 tccgtgcgca cgtaaatcag gtacaagaac gttgaatcct ttctctgcat atcttttacc
    12241 tatatgagac atgtctcttt tccctgtgct tcggtaatca tgtacgcaaa tgacccattt
    12301 attctgctta tttggatgga tgaacatctg accagctagt ttcaacccgt cataactttt
    12361 gattgttttg ggtgttccct gctcccaaaa gctttcacac tcttcttcta atttttgtcg
    12421 ttttttttct actgacgtga ctgcagcagg gtccatcaaa cgatgaccag tgtcttcata
    12481 ccagtcatat cctctctgta ctcccgctct tactaatttc tttgcataaa aataagaaag
    12541 aaaatggtaa ctgatcccta taattatcag aataagaatg aaataaaaaa taaccattgt
    12601 acacccgccg ctttctgcca aactataatc taactattat ccaatgtacc gatccatagg
    12661 attctttatt ttcggcacac gtaaattcca tttctttttc attgtatcat ttacttaaag
    12721 ttctcctcaa tagatttact tgtaagagag catttacatt cgcaataaaa gccagtatac
    12781 taatttcgtg cattataatc aagacgctcg tcttggactg gttcggaaac ttcccagaat
    12841 aaaaaactaa gtatctctaa agaaaggaga ttggaaataa tgcgaaaagt aattattgat
    12901 tgcgatccag ggatcgacga cactttagct ttatcattag ctgtcaaatc ccctgatatc
    12961 gaagtagttg ctattaccgt agtttgtggg aatgtccctg cagatatagg tacgcagaat
    13021 gtgctgaaat gcctggaacg ctgtgatcgt ttagacattc ctgtttatca aggaatggaa
    13081 aaacctttga agcaaccttt catcagtgca caagacactc atggtatgga tggtttaggg
    13141 gaaacaaatt tcccgatgat cttgagaaaa caggcagaac ctctccatgc cgttgatttt
    13201 ttggctgatt atttcaaaga aaagacaaat acatcagtca ttgctttggg tcctttgacc
    13261 aatatcgctt ttgctttgaa agtcaaccca aatattggga aacatatgga tcgttttgtc
    13321 tcgatgggtg gaacttacaa aagccatggt aactgttcgc cagttgctga atacaattac
    13381 tggtgtgatc ctgaagcagc ttcttatgta ttcgagaatc tcaaacaaac gatagaaatg
    13441 gttgggttag atgtgacaag agaaatcgtc ttgacaccga ctatcctcga atactgctgt
    13501 caaatgaatc ctgaagaggg agagtatcta aaagcgatca ctcgttttta ttttgacttc
    13561 cactggaaac aagaaagaat tttaggatgt gtcatcaatg atccgttagc tgttgcttat
    13621 tttatcgagg gggccatctg tgaaggtttc aaaagcttca ctgctgtgga aactcaagga
    13681 ataagtcgtg gacaaacatt ggttgatcgt tatgaatttt ggcagaaacc tgctaacagt
    13741 aaaattatga caaaagtaga tactcgtctt tttttccgaa agtttttaac cgttctttta
    13801 aatgcacaag aagaaacgat tatgaaagat ttggaaaggt taaagatggg ctaacaaaat
    13861 gaataaaaac aaaatggcaa ctcgcgtact tacagtgatg gctttgtgta ttgggatcaa
    13921 ttatattgga ggaacgattg ctttatggct tcgtttgcca atctatctcg attctatcgg
    13981 aacgattttt gctggtgcat tgcttgggcc tgtacctgga atgctgacag gattgtccag
    14041 cggtatttta agtggagtga ctacagatat tttttctctg tattattcgc caatccaaat
    14101 tctcacaggc ttgcttgctg gattgatttt gccaagatat ctcggcaaag ataaaaacag
    14161 cttgaaactg ttattactcg ctttgatttt gtcggtacct ggaacgatcg tttcttcgat
    14221 cattaccgtt cagttatttg gcgggatcac ctcctcagga tccagtatga tcgttcagct
    14281 attacatggg ttaggtttaa gtcagacaac aagtgtgatc ttggtacagg caggtacaga
    14341 ctaccttgat cgtttgttgt ctatcgtcgt tgtttcatta gtcatcacta tgttgccaca
    14401 acgcttgata tattcaaaaa gaaaaatagg ctgaataaac agagctggat tagcaaaata
    14461 atgctaatct ggctctgttt tttcatttat taaaaaaatc ttacgctaag taggataaaa
    14521 taattccttg atatttttca atcatatcca aataattatc gatttcaaca tactcatcta
    14581 cttgatgagg caaagtaacg acaccaggcc caaagacgac aaagtcgaag gaatggttag
    14641 ctttcgtaaa ttcggctgca tccgttgttg ctgccgctcc aactaaaggt aatggctggc
    14701 tgaattgttg ctgaatgcaa tgaatcaaag gagaatctgg atcagctttg acaggtattt
    14761 tgttgtaatc gatcatcaat tccaaatgat agtctgtctc ttgattcaat tcattgacga
    14821 ttgattgcag caatgcaatg attttatcat ttgggtattc tggaatcgat cgaatgttcc
    14881 cttggagctg cgcatggctt gggatgctgt tgacttgatt cccgccactg atcaatgtaa
    14941 cattatggat tgtttttcct aggacaggat tctcgattgt ttcagcgagg tgattcattt
    15001 cagcatttgc tttcgtaatg aattcattta ggtgattgat tgcattataa ccttggtctg
    15061 gcatagagct atgcgcttct tttccgtgcg aggtgactgt atagttgatt gatcccatgt
    15121 gcgtatacat caaactgtaa ttagttggct ctccgatgat caaggcatct aagtcatcta
    15181 catagcctgc tttcgtgagc tgttccccac ctagttcacc cacttcttct ccgacagtgg
    15241 ctaataattt gactgttccg ttaaatggtt ttcctgactc tttcagttcg atcatggcaa
    15301 tcaccattgc tgccaagcca ctcttcatat ctgtagcacc acgtccgtac aaacggttcc
    15361 catggatttc tgctgcaaag ggtgcatagg tccaagacga ttcatcacca gccgccacga
    15421 catccatatg cccagatagg cctaacactt ttcctgattg gcccttttgg taacgagcaa
    15481 tcaaattatc tctaccatct ctgtaagaaa caatctctcc tgttatgtca tgctttgcca
    15541 aaagcttatt caaataggct gctacttcac cttcgtttcc attcactgat ttaattcgga
    15601 tgatctcttg taaaatcgcg attttttctt cttttttcat ctaatcctct cccttgccat
    15661 ttctttttat tgtatttgag tgtgctcgaa ttttcaaata ggagcaacca aagtaaaaat
    15721 gaagaaagag agccacttta tgaaaaatat gctgctactt ccctcctatt ttatttatac
    15781 gagaggactt gctcatagat tcctattcta ctgttctatc cttaaaagct cttatatgat
    15841 gctagttatt gttagctttc ctttttcaag gatgatcttt tcttgtacca ttctttgtaa
    15901 acatcatata cagaagctag ttgcaaaaaa aactctctac ctgctgatat t
//
LOCUS       DARBDN010000060        15803 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000060 DARBDN010000000
VERSION     DARBDN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.060"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(362..728)
                     /gene="ssrA"
                     /locus_tag="SCH06_001876"
     tmRNA           complement(362..728)
                     /gene="ssrA"
                     /locus_tag="SCH06_001876"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(899..1672)
                     /locus_tag="SCH06_001877"
     CDS             complement(899..1672)
                     /locus_tag="SCH06_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078431.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1816..2166
                     /locus_tag="SCH06_001878"
     CDS             1816..2166
                     /locus_tag="SCH06_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEG1078432.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2147..2863
                     /locus_tag="SCH06_001879"
     CDS             2147..2863
                     /locus_tag="SCH06_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078433.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2863..4311
                     /locus_tag="SCH06_001880"
     CDS             2863..4311
                     /locus_tag="SCH06_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1078434.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4381..4890)
                     /locus_tag="SCH06_001881"
     CDS             complement(4381..4890)
                     /locus_tag="SCH06_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078435.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4880..5605)
                     /locus_tag="SCH06_001882"
     CDS             complement(4880..5605)
                     /locus_tag="SCH06_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078436.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5828..7948)
                     /locus_tag="SCH06_001883"
     CDS             complement(5828..7948)
                     /locus_tag="SCH06_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEG1078437.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8178..9356
                     /locus_tag="SCH06_001884"
     CDS             8178..9356
                     /locus_tag="SCH06_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEG1078438.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9372..10130
                     /gene="aroD"
                     /locus_tag="SCH06_001885"
     CDS             9372..10130
                     /gene="aroD"
                     /locus_tag="SCH06_001885"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEG1078439.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10153..10638
                     /gene="ybaK"
                     /locus_tag="SCH06_001886"
     CDS             10153..10638
                     /gene="ybaK"
                     /locus_tag="SCH06_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HEG1078440.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10709..11962)
                     /locus_tag="SCH06_001887"
     CDS             complement(10709..11962)
                     /locus_tag="SCH06_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEG1078441.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12080..13429
                     /gene="gdhA"
                     /locus_tag="SCH06_001888"
     CDS             12080..13429
                     /gene="gdhA"
                     /locus_tag="SCH06_001888"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEG1078442.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13541..14887
                     /locus_tag="SCH06_001889"
     CDS             13541..14887
                     /locus_tag="SCH06_001889"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEG1078443.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15195..15581)
                     /locus_tag="SCH06_001890"
     CDS             complement(15195..15581)
                     /locus_tag="SCH06_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEG1078444.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(15630..>15803)
                     /locus_tag="SCH06_001891"
     CDS             complement(15630..>15803)
                     /locus_tag="SCH06_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEG1078445.1"
                     /translation="TVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQ
                     RRFEGTLRYSLGY"
BASE COUNT         5165 a         2819 c         3174 g         4645 t
ORIGIN      
        1 aattgttcta gaaaaacttt tgagtgaaca attattttat gttaggatga attaatttct
       61 ctagagttta taattaaaaa acttatttga aggaacatgc ttaaaccata attgtgtttt
      121 tccttccatc agcataaaag ttcacctcaa aaagagtgta cgaacaaaag ttctttttgt
      181 aaaccttaaa atagattttc ctgaatacgt attggggatt tctaaatgtt tgaatgtttt
      241 tttgaatgca aaatcaatgc aaaaaatttt gtatttctct acttttctct ccttgaccaa
      301 aataaaaaaa cgttgattta acaacgtttt tcatacatgt ttatctgtct caaccataca
      361 tatatggaga cggcgggagt cgaacccgcg tccaaacaca tcgccactta aaaatctacg
      421 ttcatagtca actcatttaa ggattcactt tacagcttgc cgagtgacag gcattctgta
      481 tcgctagtct gatgttctct ttttcaactt acagacggaa agttgaaacg tatcccacta
      541 aagttaggac ccttactcga gcacatgggc gatgccgaga ggatctacgc taactgtttt
      601 taggcagcta aagcgtaaga gttgttttcg tttttagcag ttatatttaa ctgtaacgtt
      661 tttacgtaga cgtaacctac gaaacgcaat tcaagctcga ctgtgcctgt cgaatccgta
      721 acgtccccgt tagctaacaa gggttacgtg tatttttcat acaaaattag tatagcatat
      781 attgggataa attcaataaa aaagcgaatc atatcccatt atttatataa taactgcccc
      841 tttcttaaga aaaaataagc gattttctta agaaaagagg tagcttcaaa aaaagatctt
      901 aaatcagatc aaaatacttc aatgcgtgga caattccgcc ttctgtattt ttctttgtga
      961 taaaggtaga aagttctttt aatccgtcat aggcgttgcc catagcgatt ttgttgtcgc
     1021 aagcttccaa caaggcaaaa tcattcggac catcgccaaa tccaaaagta ggaacttttt
     1081 ccagctgaag ttctttttgc agacgtttga cacctgcccc ttttgagatt cctttcttca
     1141 ctgtatcgat cgagtaagga ccattccgat aaaaagttag ctcaggaaaa tgttcgtgat
     1201 agtattcgtc acctgattga gataagatca gcaacatatt tactgtgttt tctttaaagc
     1261 ctaaaggatc aatttccgga acatctgaat gaatgaagtc gtaagcattg atcattgttt
     1321 ggctatgacc ggtacaccag attttctgat cgttatagta agaaagttca tgaccgttca
     1381 actgtacatg atcatacatt ttttgacatt cttctgaaga aaatgtttga gaatagattt
     1441 cttcgccgtc tactcgaatg aaagaaccat tcatggtgac cgcagaagta atgcccgcat
     1501 cttccatgat agagtggatt tctgcttctg tacgtcctgt agcgatgacg gggagaacat
     1561 tgttttcttt taatgcgttc atagcttttg ccacttcggg tgtgattttt gatttcgcat
     1621 ctagtaatgt tccatcaaga tcaaagaaag tgattgcacg ataatttgac acaaataaaa
     1681 ctcctttttt attggaataa gtttatctta acaaagaatg aacaaaagac aaacctttcg
     1741 tgaagaattc ctgaacatat tggttcagtc aacaatttag agtatactat aagaagagaa
     1801 tttaggaggg aaagaatgat ttttttcagt attggtatct tattcttaat aattggcagt
     1861 ctttttcgga ttctgccctc aaaaggaaat ctgccttttt atgggtatca ttcgcctctt
     1921 gccgcaaaaa cagacgctca ttggcggctg gctcaaaaga caagcggaaa ctggtttttt
     1981 cttatgggct tactgatggc attgatcggc tattatttaa agacatctgg gcatacgaat
     2041 tattttctga ttgaaatgct tctgctagta tttccaatta tgcctatttt tattatgaca
     2101 gaaaagaaat tacagaaata tgacctggaa actggaggga acgataatga atattttaat
     2161 gattgaagat aatcaatctg tttctgaaat gatgcagatg tttttcttaa atgaaggttg
     2221 ggaagcaact ttcaagtatg atggaaaaga agggctcgat gcctttttag aaaacccaca
     2281 acattgggat atgattacac tagacctgaa tttgcccaca ctggacggta tgctagtagg
     2341 aagagagatc cgcaaagttt caagtactgt gccgattatc atgctgacag ctagagattc
     2401 tgaaagcgat caggtgatcg gcttagagat gggggcagat gattatgtca caaaaccttt
     2461 cagtcctctg acgcttattg ctcgaatgaa agctttgcat cgccgtagtg agttggcaga
     2521 agcaagagaa gaagcagcag tttcagatga tcattttgat atcgagacta gtcatttcaa
     2581 gatgaatacg aaaacacgag aagcgtatct ggacaaccgg ccaattgaag gactgacgcc
     2641 taaagagttc gatctattgt ttactttagc aaaaaaacca cgtcaagtat tctctcggga
     2701 gcagttgctt gaattagtct gggattatca gtactttggt gatgaacgga cagtggacgc
     2761 ccatatcaag aaattacgac aaaaaatcga aaaggtcgga ccacaagtca tccaaactgt
     2821 ttggggagtc ggctacaaat tcgatgattc tggtgttgcc taatgcgtta tttgtatcag
     2881 caactcttag ctttttgcgg aatggtcgcg ttgatcttat tgatcgttgg agtttctttt
     2941 acacaactga caaaacaaac gattgaagaa aacaattacc agcaactgtt tggatatgct
     3001 gaatcagttg aaaagacaac gcaaacctat gccgatacgc tcccgcagtt tagtcaagat
     3061 caggcgtttc aaaatgcatt gctgctgaca gagcaagtac tgacagaaca aaatgtgaac
     3121 tttatattta tcgataaaaa cgaacgtgtc atttatccga ctaatacagc tttactgaat
     3181 tttaccttaa cagctgatca atggaaaaat ctgaggaatg gacgtcaaga aaaattcaca
     3241 tcgaataaaa atattttagg acaagcacag gcgacctctt acgcacttgt gccatttaat
     3301 ttgaatcatg aattctatgg agcacttgta gttagtcaac ctgcgcgaaa tatcgataac
     3361 agcgttcgtc caattacact gaacctgttc aaaggattta ttttttccag tatcgttgca
     3421 gttattgcca gctatgcttt tgcagcattc caagttaagc gtatcaatcg gttaaggaat
     3481 gcgacgaaag aagtgacgaa tggtaatttt gatgtacagc tccccgtaca tgacaaagat
     3541 gaatttgatg agttagcaga tgatttcaat aaaatgacga attcattgaa agaatctcaa
     3601 gcagaaattg aagaacaaga aaatcgtcga agacaattta tggcagatgc ttctcacgag
     3661 atgagaacac ctcttacgac aatcaacgga cttctggaag ggttagaata caatgcaatc
     3721 cctgaaaatc agcgagaaaa cgcgattaaa ttgatgaaaa atgaaacaga gcgtctgatc
     3781 cgtttggtga atgaaaactt ggattatgaa aaaatccgta cgaatcaaat cagtatggtc
     3841 attaaaaaat tcaatggaac agaaacattg aaaaatattg ttgcacagtt agaagctaaa
     3901 gcagaagcag caggagatac attgacattg aaagccgttg atgatattga tgtttacgct
     3961 gattatgacc gatttgtcca aatcatggtc aatattattc aaaacgcgat acagtttact
     4021 gaaaacggcc aaatcacgat tactttagaa aaaggctatc ttgaaacgat catcacgatt
     4081 gaagatacgg gaattggaat gtctgaacaa caaatgaaaa gtatctggga tcgttattat
     4141 aaagtagatc cttcaagaaa aaatacaaaa tatggtgaat caggattagg tttaccaatc
     4201 gtgcagcaac ttgtacgctt gcataaagga aaattagaag tagaaagcga actaggaaaa
     4261 ggaacaaaat tcgctgttcg tttgcctgac gtagaaatca aaaaagagta aaaaacaagc
     4321 ggtataaaag atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat
     4381 ttagcccgcg ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt
     4441 aaagagtaag ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc
     4501 ttggatctcc aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt
     4561 ggaaagcaag gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc
     4621 cgcacaatta agcaaggaag gagagatatc aagtttttct tgataggcca aacgatcttg
     4681 tttgatttct ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa
     4741 catcggccaa tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt
     4801 tttcaagtgc tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg
     4861 ttcagcatga atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat
     4921 ggataaaaaa agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa
     4981 gagtttgggc aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg
     5041 taaaaaaagt ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac
     5101 ggatatctgg cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt
     5161 cataaactga ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag
     5221 gaaagaacag ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggc
     5281 gccaattgat caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa
     5341 ggaaggcaaa tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt
     5401 ctaaagccgg aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga
     5461 cttgattggc taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag
     5521 cagaaaagct tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag
     5581 cagtagcata gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat
     5641 atgaataaag tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt
     5701 aaaaagcaag aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga
     5761 acactgttta ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt
     5821 tattttgtca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt
     5881 tataaagatc aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac
     5941 caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg
     6001 tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt
     6061 ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta
     6121 cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt
     6181 agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat
     6241 ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt
     6301 gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg
     6361 tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg
     6421 tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga
     6481 caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca
     6541 aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt
     6601 tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg
     6661 aataaggata atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt
     6721 ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat
     6781 tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt
     6841 atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca ctagtgtaac
     6901 cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg
     6961 tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc
     7021 ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt
     7081 ggtaaagact attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt
     7141 tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctt
     7201 tagcgagccc gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta
     7261 cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa
     7321 caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga
     7381 atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa
     7441 tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca
     7501 acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca
     7561 catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag
     7621 cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg
     7681 aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag
     7741 ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa
     7801 acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa
     7861 aaatcgtttt caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca
     7921 aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca
     7981 gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac
     8041 aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt
     8101 catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag
     8161 ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa
     8221 aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat
     8281 gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga
     8341 ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg
     8401 aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta
     8461 ccgcttttcg tatattcaat ggagaaggag acggaatcgg cggtctgatt gttgattatt
     8521 atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat
     8581 tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag aaaattcgat
     8641 ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct
     8701 tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg
     8761 ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga
     8821 aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag
     8881 gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac
     8941 agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg
     9001 agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac
     9061 caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg
     9121 tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg
     9181 cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg
     9241 tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct
     9301 ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg
     9361 agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt
     9421 gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg
     9481 aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg
     9541 atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat
     9601 ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg
     9661 acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca
     9721 aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa
     9781 ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga
     9841 atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac
     9901 gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta
     9961 ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc ggaacgacgg
    10021 gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac
    10081 cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg
    10141 aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa
    10201 caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg
    10261 tcatcggtcg ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct
    10321 gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta
    10381 aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg
    10441 gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt
    10501 cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga
    10561 agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt
    10621 gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg
    10681 tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta
    10741 catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca
    10801 gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa
    10861 tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt
    10921 tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg
    10981 cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct
    11041 caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg
    11101 tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca
    11161 ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg
    11221 gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac
    11281 cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct
    11341 cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg
    11401 tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag
    11461 tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta
    11521 taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg
    11581 tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg
    11641 ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga
    11701 agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc
    11761 caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac
    11821 cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg
    11881 cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga
    11941 tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa
    12001 gaaaacagaa aaaaaatgtt ttgagccaaa agagaaaatg agctaaaatg agggaagata
    12061 agcaaaggag cgtggaacga tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa
    12121 gctacatcaa aaggatcaag ggcaagaaga atttttacaa gcaatcgatg aattcatgcc
    12181 cacggttatg tcttttttgg acactcatcc cgaatatatc gaaaagaata tcttagaact
    12241 tttaacggaa ccagaaagag ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa
    12301 ctggcgagta aatagagggt accgtatcca atacaactca gctatcggcc cttataaagg
    12361 tggattgcgc ttccatccta gtgtcaatct aagtatcttg aaatttttgg cttttgaaca
    12421 gattttcaag aatagtttaa ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt
    12481 cgatcctaaa ggaaaatctg ataatgagat catgcgtttt tgtcaaagtt tcatgctgga
    12541 attgtcaaaa catatcggcc catcgattga tgttcctgcg ggagatatcg gtgtaggagc
    12601 tagagaaatc ggctatttgt tcggcgaata taaacgattg aaaaaatatg atactggtgt
    12661 gttgacaggt aaacctttgg atttttgggg aagtaagata cgtacggaag ctactggtta
    12721 tggattagtg tattatgtca aacatctatt gaacgaagaa aaagattcat ttaatcaaaa
    12781 aacagttttt gtttccggaa gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga
    12841 gctaggcggg aaagttgtta catgttcaga ttctagcggg tacatctatg atccagaagg
    12901 aatagatgtg aaactattga aagaagtcaa agaaatcaat agacaacgtt tgacggaata
    12961 cgcaaaccaa cgtccttctg ctatttatca tgctggagaa tctgtttgga cattgaaaga
    13021 aaaagcggat atcgctttgc catgtgctac tcaaaatgaa atagacgaaa gcttggccga
    13081 aatcttagta gaaaatggga tcaaaatcgt agcagaaggc gctaatatgc catgtacagt
    13141 aaaagctgtt tctgttcttc atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa
    13201 tgctggagga gtagcagtat ctgctttaga aatgagtcag aacgtccagc gattgacttg
    13261 ggaaagagag caagtggatg agcagctgga tcaaatcatg gaaacgattt accatacgtg
    13321 tcgccaaaca gcagccgagt acggcgacga aaaaaatctg cttcttggag caaatgttgc
    13381 tggatttgaa aaagttgcca aagcaatggc agcagaaggt ttagtttgaa aaatgaaact
    13441 ttcttggaaa tattgtcagc attttgttta tttgcttgaa aaataataaa aaaaaacgta
    13501 aagtattacc tgtagagtaa acctataagg aggagaacaa atggcacaca ttcattttga
    13561 ctattcaaaa gtagcaccgt ttgtcaacga acaagagtta gggtacatgc aaagccaagt
    13621 aacagcagcc cacaacgaat tacgggaagg tactggcgca ggaagcgact tccgcggctg
    13681 gatcgattta ccaacgaact atgacaaaga agaatttgca cgtatcaaag aagcagctaa
    13741 aaaaatccaa tctgattctg aagtattagt tgttatcggt atcggtggtt cttatttagg
    13801 cgctcgtgca gcgatcgact tcttgaatca cacattcttc aatttattag atagcaacac
    13861 aagaaaagca ccacaaatct tctttgccgg aaattcaatc agctcaacat atattgctga
    13921 cttgatcgaa gtaatcggtg atcgcgactt ttcagtaaac gttatttcaa aatctggaac
    13981 aactactgaa ccagcgattg cgttccgtgt attcaaagag cttcttgtta agaaatatgg
    14041 acaagaagaa gcaaacaaac gtatctacgc tacaacagat aaagcaaaag gtgcagttaa
    14101 agtagaagca gatgcagaag gttgggaaac tttcgtgatt cctgatgaca tcggcggacg
    14161 tttctctgta ttaactgctg ttggtttgtt accaatcgct gttagtggtg cagatatcga
    14221 tgcattgatg caaggtgccg ctgatgcaag caaagcatac tcaagcgaca aactagaaga
    14281 aaacgaagct taccaatacg cagcaatgcg caacattctt taccgtaaag gcaaagtaac
    14341 tgagttgttg atcaactatg aaccaggaat gcaatacttc tcagaatggt ggaaacaatt
    14401 gtatggtgaa tctgaaggaa aagaccaaaa aggcatctat ccttcaagcg caaacttctc
    14461 aactgatttg cactctttag gacaattcat ccaagaagga cgtcgcaata tttttgaaac
    14521 agttgtgaag gttgaaaaac ctcgtaaatc aatcacaatt cctgaacaag cagaagattt
    14581 agacggtcta ggctacttgc aaggaaaaga agtggacttc gtaaatacaa aagcatttga
    14641 aggaacattg cttgctcata cagacggtga cgtgcctaac ttgctagtca aaattccaga
    14701 aatggatgct tatacattgg gttatacaat gtacttcttt gaaattgctg taggtatttc
    14761 aggttacttg aatggaatca acccattcga ccaaccaggt gtagaagctt acaagaaaaa
    14821 catgttcgca cttctaggca aaccaggctt tgaagatctt gctaaagaat tgaacgaacg
    14881 cctgtaagat aagggttttt cgctagattt aaataatcag tgatagaaac atgttcgctt
    14941 taaaatgaaa actggtaccc atttaggtac tcaaacatac tgcatcgttt attcagaata
    15001 aggggctgtg acaagacgtt tgtcacagtc ccttgtttgt atagaaatcg attgattgcc
    15061 ttgctcttta gtttgtttta ggactttaag aacagtgagg ctgacttcga aggttaattc
    15121 tgtttttttg ttttctagaa tcagtaagca aaaaagcact cacttcgagt gcttttttgc
    15181 gatatattct tagcttaaga taggcctaat ttttctttta cagatgaggg taccttatcg
    15241 ctggtaatta cttttttctc tatgatccgc ttttcgcttg ctttcaactg caagatcgtt
    15301 ccttcggggt aagcagaacc attggcagag tcaccagaag taatgacatc gaaatctaac
    15361 tgtctttttt caccgttttc agcataagca tctacgttgt atttaaaacc tcttccaatt
    15421 acttccccat tatctgcttt gatatcagtt tctgcaggca ttggagcttt gactaccgca
    15481 taataatctt tacctacata agtagactga tagtagtccc aacctttcca tcctataaaa
    15541 gcaatcaata tgataacgat caaccctaaa atttttttca tgaaagatct ccttttttat
    15601 ttttattata cccgtggtgc tagttaattt taatatccta aagaatatct caaagttcct
    15661 tcaaaacgtc gttgtgctcg acttaataga acactgtaag ccagtaatat gctttcaaat
    15721 ctactctcta gccctttaac agaacgtgag ttgaaatttt gacaacctaa tttttctaag
    15781 gaagaaaaaa cagtctcaac tgt
//
LOCUS       DARBDN010000061        15796 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000061 DARBDN010000000
VERSION     DARBDN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.061"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            24..776
                     /locus_tag="SCH06_001892"
     CDS             24..776
                     /locus_tag="SCH06_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEG1078446.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            773..1687
                     /gene="pfkB"
                     /locus_tag="SCH06_001893"
     CDS             773..1687
                     /gene="pfkB"
                     /locus_tag="SCH06_001893"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEG1078447.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            1705..3636
                     /locus_tag="SCH06_001894"
     CDS             1705..3636
                     /locus_tag="SCH06_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1078448.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(3747..5306)
                     /locus_tag="SCH06_001895"
     CDS             complement(3747..5306)
                     /locus_tag="SCH06_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEG1078449.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            5461..7695
                     /gene="pcrA"
                     /locus_tag="SCH06_001896"
     CDS             5461..7695
                     /gene="pcrA"
                     /locus_tag="SCH06_001896"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEG1078450.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            7712..9748
                     /gene="ligA"
                     /locus_tag="SCH06_001897"
     CDS             7712..9748
                     /gene="ligA"
                     /locus_tag="SCH06_001897"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEG1078451.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            9854..10159
                     /gene="gatC"
                     /locus_tag="SCH06_001898"
     CDS             9854..10159
                     /gene="gatC"
                     /locus_tag="SCH06_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEG1078452.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            10159..11631
                     /gene="gatA"
                     /locus_tag="SCH06_001899"
     CDS             10159..11631
                     /gene="gatA"
                     /locus_tag="SCH06_001899"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEG1078453.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            11628..13058
                     /gene="gatB"
                     /locus_tag="SCH06_001900"
     CDS             11628..13058
                     /gene="gatB"
                     /locus_tag="SCH06_001900"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEG1078454.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            13068..14123
                     /locus_tag="SCH06_001901"
     CDS             13068..14123
                     /locus_tag="SCH06_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEG1078455.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            14234..15607
                     /gene="rlmD"
                     /locus_tag="SCH06_001902"
     CDS             14234..15607
                     /gene="rlmD"
                     /locus_tag="SCH06_001902"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEG1078456.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            15610..15738
                     /locus_tag="SCH06_001903"
     CDS             15610..15738
                     /locus_tag="SCH06_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEG1078457.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
BASE COUNT         5370 a         2899 c         3473 g         4054 t
ORIGIN      
        1 tttgtattga ggtgatcgtg aaaatgctta cagaggaacg cagacaaaaa atcctagact
       61 tgcttgaaca gcagaaaatc gtgaaatcac aagatcttgt aaaccttttg aatgcttctg
      121 aatcaacgat aagacgtgat ttacaagagc tggagaatag tgggtttcta gaaagagttc
      181 atggcggagc taagaaagag caattattga attttgagca gaatatgagt gaaaaatcac
      241 tcaaaaacgt tcacgaaaaa cagcaaatcg ccaaatcggc agctgaaacc attaatgacg
      301 aagatgtcat ttatttagac gctggctcta ctacgttaga aatgattcct tttctgcaag
      361 gaaaacagat cacagtagtg acaaattccg ttcaacatgc ggcaaattta gttgatttgg
      421 agcttgctac cattatttta ggtggaacga taaagctggc aactaatgct gttttaggat
      481 ctaatgcgat agaacaacta aaaaattttc attttaataa agcatttatg ggaatgaacg
      541 gtgcccatct tgaacaagga ttcacgactc cggatccaga agaggcagct gttaaacgtt
      601 tagccatgaa aaattccgaa gagacatttg tattgattga tcataccaaa ttcaaccagt
      661 tgtccttcac ctctgttgca cctttggaag cagccacgat cataaccgag cgttgtccat
      721 tagaattcgt taatgaattc cgtgaaaaga caacaattaa ggaggcaata caatgattta
      781 cacagtaaca cttaatccat caattgatta tatcgtacgc gtagatgggt taaaactagg
      841 cgatttgaac cgaatgaagg aagacttcaa gttacctgga ggaaaaggga tcaatgtttc
      901 ccgtattttg aaacggatcg attctcaatc tacagcacta gggtttttag gagggttcac
      961 tggcgaattt atttcgaagt ggcttgaaaa agaacaaatc cagtctttgt tcacaaccgt
     1021 aaaagaagat acaagaatca atatcaaact aaaatcagac actgaaactg agatcaatgg
     1081 cttaggccca tctatttcag atgaagaaat cgatgagttg aagcaagcat taggaacagt
     1141 aggacaagga gatatcgtcg tattgtcagg aagcgcgcca gctagcctgc gaaaaggatt
     1201 ttatcaagaa ctgattgata tcattcgaga aaaaggtgca gatttcgtga ttgatacaac
     1261 aggtgatgac ctaaaaaatg cacttgttaa gaaaccgttg ttgatcaaac caaacaatca
     1321 cgaattagct gagctttaca acacaacctt ccaatctgta gaagaaatca ttccgtatgg
     1381 gaaaaaatta ctagctgaag gggcacagaa tgtgctgatc tcaatggctg gagacggtgc
     1441 tttgctcttc acggaacaag gaacttataa aacgaatgta ttagttcgcc cattgaaaaa
     1501 ttcagtaggt gcaggggatt caatgattgc tggctttatt ggggcttaca gccgtacgaa
     1561 agatccaatc gaagccttta aatggggagt tgcttgcgga agcgcaacag ctttttctga
     1621 tgacttggca gctcgcgaat tgattgatga gttgctgcca gaagttgaaa tcacaaaaat
     1681 tgattagttt caaggaggat aatcatgaat atcaaggatt taatggtcaa agaagcgatg
     1741 atcatggatt tgcaagcgac tgataaaaaa ggcgcaatcg atgaaatggt ccaaaaaatg
     1801 tttgatgccg gccggatttc cgatatcgaa acatataaag aaggaattct agcccgcgaa
     1861 gcacaaactt ctacaggtct tggtgatgga atcgccatgc ctcacgcgaa aaacagtgca
     1921 gttaaagaag caacagtttt attcgcaaaa agccaaaaag gagtagatta tgaagcctta
     1981 gacggacagc caacttatct gtttttcatg atcgcagctc cagaaggcgc aaacgacaca
     2041 catttgcaag cattagcagc actatctcga ttgctgattg atgcagattt cgtaggaaaa
     2101 ttaaaagaag caaatacacc agaagaagtc caagacttgt tccaaacagc tgaagagcaa
     2161 aaagaagcag aagaaaaagc agaacaagaa acacaagctg cagaagcttc tgctcatcca
     2221 gaaagaaaat tcgttgttgc cgttacagct tgtccaacag ggatcgctca cacttacatg
     2281 gcagaagatg ctttgaagaa aaaagcgaaa gaaatgggtg tggagatcaa agtcgaaacg
     2341 aacggttcag aaggaatcaa aaaccgattg actgctgaag acatcgcccg tgcagaaggt
     2401 gtaatcgttg cagcagacaa aaaagtagag atgaatcgct ttgacggaaa agaactgatc
     2461 aatcgtcctg tcagtgatgg tatccgtaaa ccagaagagt tgatcaatct agcccttagt
     2521 ggtactgcac cagtattcca tggtgatgga aaagaaagca gttcagaaga aggaaatgcg
     2581 gatggtacta tcggacaaag aatttacaaa gatttgatga acggcgtatc acacatgtta
     2641 cctttcgtta ttggtggagg aatcgctatt gcgctttctt tcatgatcga ccaatttatt
     2701 ggcgtgccac atgatcaatt atcaaatcta gggaattaca atcaagctgc tagctggttc
     2761 aaccaaatcg gacaagctgc atttggtttc atgctgccgg tattagcagg atttattgct
     2821 tcaagtatcg gtgaccgccc tggtttgatc gttggatttg ctgctggtgc attagctaat
     2881 acaggcggtg caggattctt aggtgcactg attggtggat tcttagctgg ttatgtcatc
     2941 gtatttttac gtaaattatt caagaactta ccaaaatcat tggatggaat taaaacgatc
     3001 ctcttttatc cagtgtttgg cttactgatt actggtttct tgatgttgct ggtcaatgtc
     3061 cctatgaaag caatcaatga tgcattgaac ggtttcttga caagtatgag tggttcgaat
     3121 gctgctttac ttggtgcatt attagctgga atgatggcgg cagatttagg cggtccaatc
     3181 aacaaagccg cttatgtgtt tggtacagca actttagcta cgactgttgc aactggcgga
     3241 agtgtcgtga tggcttctgt tatggctgga ggaatggtac ctccattggc aattttcgtt
     3301 gctacacgtt tgtttaagaa taaattcagc aaaacagatc aagatgctgg tttgacgaac
     3361 atcgtgatgg gactatcgtt tgtcacggaa ggatcgattc catttgcagc agctgacccg
     3421 attcgtgcca ttccaagttt tattattggt tctgctttaa ctggcggatt agtcggagct
     3481 ttcggaatca aattactggc tcctcacggc gggattttcg ttgtattctt actgagtcac
     3541 ccggtcatgt atttggtgtt tattgctatc ggagcagtcg tatctggtgt gatttatggt
     3601 ttattgagaa aagctcctgc agtagcagaa gcatagaaat aaaaaagaag aggctgggtt
     3661 ttcccagcct cttctttttt tatagaatca tatagaatca agtagtgtag atgaatagtt
     3721 gttgtaaaat agtttttcca tgttcgttaa aatgattgct tcaaatttgt gatagaagat
     3781 ttagcctcga tttcctgctt gattcttggc aagtttgctt catcagtcaa gataaccaaa
     3841 atatctccta cattcatgat cgtatcaccg tgagtcaaga tttcctgatt tcctctgcgt
     3901 atagagatta gcagcatatt tttaggccaa ttgaagtctc gtaccattaa tccgtctaaa
     3961 gaactctctg ccgttactgg aaaatcaaaa gttgtccttg caccttttag tgaggcggtc
     4021 tgagtatttc caagtagacg ttccaataat gattcgtaaa ttggattacc gccgagaagg
     4081 tcattgacga tataagcaac aagagcagcc aatcctaaag gcatcagatg attaagagag
     4141 ccaaccattt ctgtcactaa aataattgct gtcagcggtg cttttccaat cgctgtgaaa
     4201 taaccagcca tggcaataac gacaaaatcc ttgatgtaga ttggatccat cccgaaatca
     4261 accataatgt ttccataaaa gctaccgatt aaagccccca atgtcaatat cggaaggaaa
     4321 atcccccctg gaagaccccc accgtaagaa atcatggaaa aaacgaatcg aagaacaaac
     4381 aaaccgataa tcataatgat tggcaaggaa gcatgtccaa aagctaaaac gatttgattg
     4441 cctccgccta gagtactagg ccataaataa ccaattggca aaatcagcaa gaaaggaacg
     4501 aacccgtgaa aataagctgg taaaggcaat cggttgtaaa attttggcaa agccagcaag
     4561 acattctgat aaataaaacc taagatgcct agaagtactc ctaagatcac taaggaacca
     4621 taatatttca acggcaaaga aggaaggtca cctagatata aaacaggtct caagccgaaa
     4681 aagtaaagag agacgaagtt agcagtgatt gctgaagcaa atgatgtcag ccaaacaagt
     4741 ggagaaaagg agtgatggat ttcttctaaa acaaagagta atcctgcgat aggagcattg
     4801 aatgctgctg caagtccgct acttgcaccg ctagaaatta aaatcttttc ttctgaagat
     4861 ggactccgaa acaattgtcc agctccttgt ccaatggatg cgccaagctg tatagaaggt
     4921 ccttctctac ctagaaaaag gcccgcacca actgaaagta caccgccaat gaactttttc
     4981 cataaaacag agaaccagtt cattgataat tccccgcgaa gctgtccctc tacttgtgga
     5041 atcccgcttc ccttgatatc cggttcattt ttgaccagat aacccacgaa aaatgctgca
     5101 aggatgcagc aaatagctag gccaattaag taaatcggct gttcccgact catttcatag
     5161 atacttcgaa ctaaatcgct tagcttttcg atagataatc gaaacaggct aacgacgatt
     5221 cctgtcagca gtccaacaaa tattcctttt agaataaaat atatctgagt cttatctaat
     5281 ttcttgattt ttcctttttt ttccattcaa acgcctcgct ttcttttaat ttagcgcgaa
     5341 atcaacgaat tgacaaggaa aaatccataa aaagaaacaa atgattttga actagctagt
     5401 ttaatgaaag ccaagaaaat gctataatta acaagattga taaaagaaag gatgttgtta
     5461 atgtcatcca aagctgaatt attaaacggg atgaaccccc gtcagaaaga agctgttctt
     5521 cacactgacg gaccattact gctaatggca ggtgcaggaa gtggaaagac gagagtgctg
     5581 acacaccgca ttgcctattt gattgaggaa aaagaagtca atccttggaa catcctagcg
     5641 attactttta ccaataaggc tgcaaaagaa atgaaagaac gtgtcaatgc gattctcgca
     5701 tctggaggcg aagatgtctg ggtatcgact tttcactcga tgtgtgtgcg tattttaaga
     5761 agagatgttg attttatcgg gtataaccgg aactttacaa tcatcgattc ttctgaacag
     5821 ctgaccttga tgaaacggat actaaaagaa ctgaacattg atccgaaaaa atatgatcct
     5881 cgaagtatat taggaacaat ctctcaagca aaaaacagcc tgcagacccc tcaggatttt
     5941 gcaaaaatgc aaggcagtta ttacgaagag attgcggcaa aatgttatgc tgcttaccaa
     6001 aaagagcttc aatataatca atgtatggac tttgacgacc tgatcatgaa tacgattcga
     6061 ttatttgaag aacatcctga ttcactcacg tattatcaaa acaaattcca ttatattcat
     6121 gtagatgagt accaagatac aaatcacgca cagtatacgc tagtcaattt attggcaggt
     6181 agatttagga acctgtgcgt cgtgggagat gcagatcaaa gtatttacgg ctggcgcggt
     6241 gcagatatgc agaacatctt ggattttgaa aaagattatc cagatgctgc agtaattttg
     6301 ctagaacaaa actatcgctc cacgaaaaac atccttagcg cagcaaacca agtcattgaa
     6361 aacaatagca atcgaaaacc aaaaaacttg tggacagaaa acaaagaagg aaacaagatc
     6421 acttactacc gtgcagataa tgaacgagac gaaacccgtt ttatcgtaga ccggatgcaa
     6481 gaagagattc gaagcaatca tcggaattac ggcgactttg ccatcttgta ccggacgaac
     6541 gcacaatctc gtgtaatgga agaaactctg ttgaaagcaa atattcctta taaaatggtt
     6601 ggagggcaca agttctacga tcgtaaagaa atcaaagata ttttagcgta tttgaatgtg
     6661 ctggtaaatc ctcaagattc aatcagtttt gagcgtatcg ttaattcgcc caaacgaggc
     6721 atcggaccag gatctatcga aaaactacgc agttttgctt ctcttcatga atggccactg
     6781 cttgaagcag cgcaaaatgt ggatctggca aatatcggtg gaaaagcagg acagcaatta
     6841 ggtgcatttg gagagatgat ccaagaagtc actcagatga tcccatactt gacagtgaca
     6901 gaattgacga aagaggtttt ggatcgtagc ggatatctag aagacttaaa aatccaaaat
     6961 acattagaag cacaagcacg catcgaaaac ttggaggaat ttttaacggt cacacaagaa
     7021 ttcgacaaac aattcgaaca gcaaaatgaa gaagacgctg atgcaccaga agaaaaacta
     7081 acggtcttct taaatgatct ggcacttgtt tccgacattg acaatttaga agaagatgct
     7141 tcccaagtga cattgatgac tttgcatgca gccaaaggat tagaatttcc agttgtattc
     7201 ctgattggtc tagaagaggg ggtttttcct ttatctcgag cattgatgga agaaagcgaa
     7261 ctggaggaag aacgccgtct cgcatatgtg gggatcacgc gagcagaaga agcgttgtat
     7321 ttaacaaatg ctttctccag aacattatat ggacggacgc aatataaccg accttctcgt
     7381 tttgtagaag aaatcgatca ggagttactg gaaatcgaag gcatgcgtcc tacgcctaaa
     7441 aaaacgcctg tattcgctaa aaaaacagca tatagctata aacagccaga gacagcggtt
     7501 gttccctcta aaagtgctac tggaggggaa aataacagct ggaaacctgg agataaagtc
     7561 aaacacaaaa aatggggtct aggaacagtc gtccgagtaa gcgggacgtc gaaggatcta
     7621 gaactagatg tggctttccc aagtcaagga gtaaaacgtc ttttggctgc ctttgcgcca
     7681 attgaaaaag cttagtagtg gagggtaaat gatggaacat gaaatgacga ttgacgaagc
     7741 tgctaaacga gcagaagaac ttcgtacaag actgaaccaa tggtctcgcg aatactacgt
     7801 agaagataaa ccaacagtgg aagactatgt ttatgataaa gaatacgcag aattagtagc
     7861 aatcgaggaa caatatcctg atttgatcac gtctgattct cccactcaac gagtaggcgg
     7921 aaaagtatta gaaggttttg aaaaagtcac tcatgatatt ccgctttaca gtttgaacga
     7981 cgttttcagc aaagaagagc tgatagcttt tgatcaacgt gtacaaaaag cagtgggacg
     8041 tgtagttgac tattgctgtg aactaaaaat agatggactt tccgtttctt tgcgttatga
     8101 agatggaaat ttcgtgagag gtgcgactcg cggggatgga actgtaggag aaaacatcac
     8161 tgaaaaccta aaaactgtcc ggtcggtccc aatcaaatta aaagaaccaa tgaacatcga
     8221 agtaagaggc gaatgtttca tgccaaaacg gtcatttgtc caattgaacc aagacagaga
     8281 agcagaggga aaagatatct ttgcgaatcc tcggaacgcc gcagctggtt ctttgcgtca
     8341 gttagattct aaaatcacag cgaaaagaaa tctggacact tttttataca cagtagctga
     8401 tttcggtcct atgcaagcaa aaacccagta tgatgcgcta gaagagctag aaaaaattgg
     8461 attccacacg aatcgggaaa aacgtctatg tcattcgatt gatgaagtgt ggtcatacat
     8521 tgaagaatat catgacaaac gtgtggattt gccctatgaa atcgatggaa tcgtcatcaa
     8581 agtgaatgaa ttctcgctac aagatcaact tggttttact atcaaagcac cgagatgggc
     8641 agcagcttac aagtttccgc cagaagaagt tgaaacgcta atcgaaaaca tcgaatggac
     8701 agtcggtcga acaggggtag taacgccaac agctatcatg acaccagtcc gagtagcagg
     8761 aacgacagta agccgtgcca gcctgcataa cggtgattat attaagttga aggatatccg
     8821 cttgaaagat acagttctga tttataaagc gggagacatc atcccagaag tttcgcaagt
     8881 cgtgttagat aaacgaccta aagacagcga agaataccaa ttgcctacac attgtccagt
     8941 ttgtggaagt gaacttgtcc atttggatga agaagtagcc ttacggtgca tcaatcctaa
     9001 atgccctgct caaatgaaag aaggtttgaa ccactttgtt tcaagaaatg cgatgaatat
     9061 cgatgggttg gggccgcgcg tactagaaca gatgtatgat aaaaaactag tagcagatgt
     9121 tgctgatctt tacaaattga cagaagaaga gttattgacg ttggacaaaa taaaagaaaa
     9181 atcagcaaat aatattttga cagcaatcga caacagcaaa gataattcgg tcgagcggtt
     9241 gattttcggg ttaggaatcc gacatgtcgg agcgaaagca gcaaaaattt tagcagaaca
     9301 tttcggtgat ctagaaacat tgagtaaaag tgactatgag tcgattattg cgcttgatac
     9361 gatcggtgat atcattgccg acagtgtagt cacttatttc agtaacgaag aagtccatga
     9421 attgatgaat gaattaaaac aagcaggcgt caatttcgaa tacaaagggc ttcgaaatgc
     9481 ccaattgcaa gaagtcgagt ctccttttaa agaaaaaaca gtagtcctta ctggtaaact
     9541 aacacgattt actcgtgaag aagcaaaaga gacgatcgaa aatcttggcg ggaaagtgac
     9601 tggtagcgta tcgaaaaaaa cggatatcgt ggtagcagga gaagatgctg gcagcaagct
     9661 gaccaaagca caagaattag gaatcgaagt ttggacagaa gatcaaatgg cagatgcatt
     9721 ggctaaaagt cgctcagtag aagaatgaaa aatgagtttt ttcagacaaa tttcaataaa
     9781 caatttcaga cacggcactc ttgtgttaaa atagagagca aagtttttaa ctcgtttaga
     9841 aagaaggggt agtatggcga ttagtgaaga acaagtgaaa cacgttgcca aattagcaaa
     9901 acttgcgttc gcagatgaag aacttgcaag ttttaccgac caattaggta aaatcatcga
     9961 tatggttgaa atgctggaag aagtagatac ggaaggtgtt ccatttacgt cgaatgtggt
    10021 tgaaacagta aacgtgatgc gacaagatcg ggcgcaagct ggatggaacc gcgatgaatt
    10081 attgaaaaat gtgccggaaa cagaagacgg ctttatcaaa gtacccgcaa tcatcgataa
    10141 tggggaggct ggcgcataat gacagaatta cacaatcgtt ctctagaaga actgcatcat
    10201 atgcttgtat cgaaagaaat cactgtacaa gatttgacaa aaacaacatt tgaacgaatc
    10261 aaagaaacag agcctgaggt cgaggcattc attacattga acgaagaaaa agcattggaa
    10321 caggcaaaag ctttagatga aaaagggatt gatgaaagca acgtccttgc tggtattcca
    10381 attggtatca aggataatat cgtaacaaaa gatatcttga caaccgctgc atctaagatc
    10441 ctttacaatt ttgaaccaat ttatgatgca acggtcatgg ataaaatcta tcaagcagat
    10501 atgatccctg ttggtaagct aaacatggat gaatttgcta tgggtggaag tacagaaact
    10561 tcttatttca agaaaacaaa aaatgcttgg gacccaacaa aagtacctgg tggctcttct
    10621 ggtggttctg cagcagcagt tgcagctgga caaattccag tttctttagg tagtgatact
    10681 gggggaagta tccgccaacc agcagctttt aacggcatcg tagggatgaa acctacttat
    10741 ggccgtgtct cacgttttgg tttgattgcc tttgcttcat ctcttgacca aatcggacca
    10801 atgacccgta cggtgaaaga taatgcatta gcattgacag ctatcagcgg ttatgacgaa
    10861 aaagacggta cttcttcagg cgtttcagtt cctgattttg cagagggact gacaggcgac
    10921 atcaaaggaa tgaagattgc tttacctaaa gaatacttag gcgaaggtgt ggcccctggc
    10981 gtaaaagaag ctgtattgaa agcagcagaa acattccgtt cattaggtgc tgttgtggaa
    11041 gaagtcagct tgcctcattc aaaatacggt gtggctgttt attatatcat tgcctcatca
    11101 gaagcaagtt ccaatttgca acgattcgat ggtatccgct acggttatcg ctctgaaaat
    11161 gtgaaatcat tagatgatgt atatgtcaac tcacgttcag aaggattcgg tgaagaagta
    11221 aaacgccgta tcatgttagg tacattctcc ttaagcgcgg gttattatga cgcttacttc
    11281 aaaaaagcag gacaagtccg tacattgatc aaacgagatt ttgaaaaagt ctttgcagat
    11341 tatgacttga tcatcgggcc atcttcacca acagttgcat tcggaatcgg tgagaacatt
    11401 aacgatccaa tcacaatgta catgagtgac atcttaacga tccctgtcaa cttggctgga
    11461 cttccaggta tgtctgtacc ggcaggttta tcagaaggat taccagttgg attgcagatc
    11521 atcggtaatt attttgatga aaaaacgatg tatcaagcgg catatgcgtt tgaacaagca
    11581 acagaattcc ataaacaaca accagctatt ttaggaggga aagacgaatg aattttgaaa
    11641 cagtcattgg actagaagtc cacgtcgagt taaaaaccaa ctcaaaaatt ttctctccag
    11701 cgccagctca ttttggtgca gaaccaaaca gcaatacaaa cgtgatcgac tggggttatc
    11761 caggcgtgct gccagtaatg aataaagctg cgctggaatt cgggatgaaa gcagctttgg
    11821 cattaaactg tgaaatctct aaagatactc attttgaccg gaaaaattac ttttacccag
    11881 ataatccaaa agcatatcaa atttcccaat ttgatcaacc aatcggtcat gacggatgga
    11941 tcgaaatcga agtagaaggt aaaaagaaaa aaatccggat cgaacgtgtc catttagaag
    12001 aagatgctgg aaaaaacatg catggtattg gcggttattc ttacgttgat ttgaaccgac
    12061 aaggcacgcc tttgatcgaa atcgtttctg aagctgatat gcgttcacca gaagaagcat
    12121 acgcttatct agaagcattg cgatcaatta tccaatttac agaagtcagc gatgtgaaaa
    12181 tggaagaagg ctctatgcgc tgtgatgcca atatttctct tcgcccttat ggacaagaag
    12241 agttcggtac gaaagcagaa ttgaaaaact tgaactcttt atctttcgtg aaaaaaggtt
    12301 tagcttttga agaaaaacgt caagcaaaag ttcttctttc aggaggagaa atccaacaag
    12361 aaacacgccg ttttgacgaa acaacgaata aaacagtttt gatgcgtgtc aaagaagggt
    12421 ctagtgatta tcgttacttc ccagagcctg atatcccgaa attcgtgatc gatgacgaat
    12481 ggattcaaaa agtaaaagct agtttgcctg agatgccagc ttctcgtcgc gaacgctata
    12541 tccgtgagtt tggacttcca gagtatgacg caatggtatt gacacttaca aaagaaatgt
    12601 ctgatttttt tgaagctgtt ttggaaaatg gtgcagatgc caagcaagca tctaactggt
    12661 tgatgggtga agtttctgct tacttgaaca gtgagaaact ggaattagct gagacaaaat
    12721 tgacacctga gaacttagca ggaatgattc gtttgatcgc cgatggaacg atcagctcaa
    12781 aaatcgccaa aaaagtcttc cgtgaattga tcacaaatgg cggagaagcc caagaagtag
    12841 ttgaaaaaaa tggttgggtg caattatctg atccgaacaa actactgcca atcattaatg
    12901 aaattttgga taacaaccaa caatctgtcg atgatttcaa aaatggaaaa gatcgtgcgg
    12961 ttggcttcct agtcggtcaa atcatgaaag caactaaagg acaagcaaat cctggtgtcg
    13021 tgaataagct acttaaagat gaattagcga aacgatagag gctgaaaatg aaaaaagcac
    13081 gcgtaattta taaccccacc tcgggaaaag aattattgaa aaaaaatttg gcggatatcc
    13141 tacaggcatt agaagaagca ggatttgaag ccagcgccta tgcaactaca ccagaaccag
    13201 attcagccaa gaatgaagca tgtagagtcg cagaactagg ttttgatcta gtagtggcag
    13261 ctggtggcga tggcacaatc aacgaagtgg ttaatggaat cgctccgctt gaacaccgtc
    13321 ctaaaatggc catcatccca gctggtacaa cgaacgacta tgctcgagca ttaaaaattc
    13381 ctagagataa tattaaagca gcagcagaag tgataaaaaa acaccaaacc gtaaaaatgg
    13441 acatcggcct ttctgataac agttacttca tcaatatcgc tgcaggtggc tatttgacag
    13501 aattgactta tgaagttcca tcagaactaa agagtatttt tggttatctt gcttatcttg
    13561 cgaaaggagc agagatgctc cctcgagtaa agccaatcaa aatgcgcttg aagtatgatg
    13621 aaggggaata tatcggaaat gcttcgatgt ttttcctagg gctgacgaac tctgttggag
    13681 gattcgaaca gatcgcgcca gatgccaaat tggatgatgg gaagttttct ttaatcattg
    13741 tgaagacagc aaatatcttt gagatcttgc atattgcagc actcatgctg aatggcggtc
    13801 gacatgtcga tgatccaaga ataatctata ccaaaacaag cagtttgttc gttgaaacag
    13861 aagatgatat caatcgacca gtaatgatca acttagatgg tgaatacggc ggggaagcac
    13921 cgatgcattt ccaaaatctt catcaacaca ttgagttctt tgccaatacc gatcagattc
    13981 ctgatgaagc aatcacaggt acagatgaag aagaattaga ggttgtcagc aaagaattcg
    14041 taaaagaagt cgaacgttta acggatgaag atatcgacgg tgacggaaaa atagcagacg
    14101 aaacacctaa tcaaaagaat taatcaaaag ccggtgctga acgtagtaag gtcagtgccg
    14161 gttttagttg tgtaattagc tgatttatag tagagttcag taggattgaa aaataggctt
    14221 aaaggagcaa aatatgacag aacagcaaat agtaaagaaa aacgaacgat atacagtcga
    14281 aatcgtcgac ttgagttatg aaggaatggg ggtagcaaaa atcgatggtt atccattatt
    14341 tatcgaaaat gcactccctg gagaagaagt agaaatacta gtagtaaaag caggcaataa
    14401 gtttggatat ggaaaagtcg aaacatttat tacacaatca cctgatcgtc agcctgtaga
    14461 aaacaatgca ttacttcgca taggtatcgc acctttagcc catttgaagt atgaacaaca
    14521 gcttgtcttc aaacaaaaac aagtagagca tgtaatggcg aagattgcta agatgccaga
    14581 agttcctgta cttccaacgg tcggaatggc agaaccattc ggctaccgta ataaagcaca
    14641 gatccctgtt cgccgtatcg atggacagtt agccaccggt ttttacaaaa agaatagcca
    14701 tgatctagtc cctatcgaag atttttatat ccaagatcct gtcatcgatc aagcaatcaa
    14761 agtagtcaga gatatcttgc aacggttcca agtacgagga tataatgaag aaaaaaatga
    14821 aggacagctt cgtcacatca ttatccgtcg tggtcattat tcccatgaaa tgatggtcgt
    14881 tttagttact cgtaaagaaa aattctttaa atccaaggaa attgctgaag ctattcatga
    14941 agaattgcca gaagtggttt cggtcatcca aaatatcaat gaagaaaaaa caaatgtgat
    15001 tttaggagac aaagaaaaag ttttatatgg cagagactat atcgaagatc agctattagg
    15061 aaaaacctat cgaatctcag caaagtcatt ttatcaagta aatactcaac aagcagagta
    15121 tctgtaccaa acagccatcg agtttgccga gttagataaa aaagacattg tgatcgacgc
    15181 ttattcagga ataggtacga ttggcttgtc tttagcagac agagtggata aggtgtatgg
    15241 gatggaagtt attccagaag caattgaaga tgcacagttc aatgctttaa ataataaaat
    15301 cgaaaatgtt cattatgaag tcggaaaagc agaaaaagtt atgaaaaaat ggcaagaaaa
    15361 agggatcaaa ccatctgtga tcgtagttga ccctccacga aaaggattag atcatcattt
    15421 tattgaatca gcaatcgaaa tgtcaccaga acgaatcgtc tatatctcat gtaatccggc
    15481 aacttttgca agagatgcta agttatttgc agaagcaggt tatgccgtga agaaagttca
    15541 gcctgtagat cttttcccgc aaacccatca tatcgaatta gtcgcttcat tcgttaaagg
    15601 agaataaaaa tggaccaaaa agaaaaaatg aaagaattga tcaaaaagaa acaaggtgga
    15661 ggccgatcca aacaaatgga aacacctaag aatgatcgta aaaacatgag aaaaggccct
    15721 aaaatcttta ataaatagac gtgctaaaga aagactaaga agtgttaact tttgttattg
    15781 tttcttagtc ttttta
//
LOCUS       DARBDN010000062        15706 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000062 DARBDN010000000
VERSION     DARBDN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.062"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(284..787)
                     /locus_tag="SCH06_001904"
     CDS             complement(284..787)
                     /locus_tag="SCH06_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEG1078458.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1146..2171
                     /locus_tag="SCH06_001905"
     CDS             1146..2171
                     /locus_tag="SCH06_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEG1078459.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2494..3372
                     /locus_tag="SCH06_001906"
     CDS             2494..3372
                     /locus_tag="SCH06_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HEG1078460.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            3848..3964
                     /locus_tag="SCH06_001907"
     CDS             3848..3964
                     /locus_tag="SCH06_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEG1078461.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            4892..5230
                     /locus_tag="SCH06_001908"
     CDS             4892..5230
                     /locus_tag="SCH06_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078462.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5324..5554
                     /locus_tag="SCH06_001909"
     CDS             5324..5554
                     /locus_tag="SCH06_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078463.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            5954..6325
                     /locus_tag="SCH06_001910"
     CDS             5954..6325
                     /locus_tag="SCH06_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEG1078464.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(6599..7291)
                     /locus_tag="SCH06_001911"
     CDS             complement(6599..7291)
                     /locus_tag="SCH06_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1078465.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(7294..8079)
                     /locus_tag="SCH06_001912"
     CDS             complement(7294..8079)
                     /locus_tag="SCH06_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEG1078466.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            8316..9716
                     /gene="lacG"
                     /locus_tag="SCH06_001913"
     CDS             8316..9716
                     /gene="lacG"
                     /locus_tag="SCH06_001913"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEG1078467.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            9741..10058
                     /locus_tag="SCH06_001914"
     CDS             9741..10058
                     /locus_tag="SCH06_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEG1078468.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            10071..11744
                     /locus_tag="SCH06_001915"
     CDS             10071..11744
                     /locus_tag="SCH06_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HEG1078469.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            11758..13389
                     /locus_tag="SCH06_001916"
     CDS             11758..13389
                     /locus_tag="SCH06_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HEG1078470.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            14261..15451
                     /locus_tag="SCH06_001917"
     CDS             14261..15451
                     /locus_tag="SCH06_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HEG1078471.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            15585..>15706
                     /locus_tag="SCH06_001918"
     CDS             15585..>15706
                     /locus_tag="SCH06_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1078472.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALT"
BASE COUNT         4984 a         2597 c         3214 g         4911 t
ORIGIN      
        1 aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat tgagatattg
       61 actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt tttgttaaat
      121 aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat aatatagtag
      181 attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc gtcatagata
      241 cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga agacggacag
      301 ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa taaaatgtat cccaaaataa
      361 tggctagacg gtctaactta tttgtcgata gatgtttgtt tagaagttga taggcccata
      421 aacctatcag tcctcctgtt gtattagtta tcaaatcagt gatgtccgct acgccaatac
      481 cgaataggaa ttgaatcaat tctgccaaga agcttacaag gaaaataatc cctaattttt
      541 tagaaaaaga aagtctcttg aaattgacat tcaaaagcac cccaaaagga aaaaagacaa
      601 tcaagttata agtggtctca cgtaataccg tcgtattttc aaaagaaaaa gtagaaaaag
      661 ggacgagatt gacattgctg taagaataag tgagaaattg tggaagatta aatgatagct
      721 tgaataaaat caaccataat agaaagaata aataaatccc taataaaaat tttgatacat
      781 accgcataga catctcctcc atttaaaaag tataccatcg aaaaccgctg aaaaatcata
      841 aaaaagtatg aagtttaagg accaacgtag ttatcgtacg aaaattagaa gctttttttt
      901 gttgggaatc cggtttcttt aacaaagcta agatagcgag ttgcttggaa aagttgctat
      961 cttttttctg tcaaaacgac tcggaatgtt cgttttttgt tctaatttct ccaagttgtt
     1021 tactttttga tactaagttt atgaaaaatc aagaaatagt tgttatacta ggtaatgctg
     1081 acaaacggga ttggcatttc atcttggttc agcttttttt ccaattacta ggaaggaggg
     1141 atagattgtt caagacttat tttcgtttca ataaaataca agataatcct tttcgtatca
     1201 tgaatctgat gctacttatc tttattgtat tatggttagg ttacataaat catgattttt
     1261 tgatttcaag tttttcatca ttagggatct ttactttttt ctattatcaa aacataccga
     1321 tgaaatattt gctgaaacgt atgtttctga tcggttgcgg actgttggtt gctttcgttt
     1381 tggggatctt atcgacttat gttttatggc ttgaaccatt tgccgtagct ttggttgctt
     1441 tttccagcag attcgtgttg cgattattcc atatttctaa accaggtggc ttgttttttg
     1501 cgatgctttc tgccatggga acgagcatgc agctgccaat cgctcaatta ccgatcgtct
     1561 cactttattt ttttatgggt gtcgtttttg ccctgattgc ggcagtgatt acaaaattac
     1621 tggattcacg gcctgagcag acaattgaaa aagcaacttt aaaagaaaga tttcacgaag
     1681 agcctttagt gatcattgat tctgttttct acagcgctgc cttatttctt tccgtttatg
     1741 tcagtcacgg cttgaatctg cataatcctt attggttgac cttgtcatgt gcatcgattt
     1801 tgctagcaga aaacttggat gcgatgaagc atcgacaagt ccaatatctg attggatcga
     1861 tgggtgggtt atgtgtgtcg gcattcttgt catttgtgcc gtttacgcag ttgcagacca
     1921 tttttctgat cacttttcta tatggaatcg cacaatttct agttgctaga aattatgcag
     1981 ttgctaatat ttttcttaat ccgatggcgt tgatgctatc tacacttatt cgtggagcat
     2041 acttgatttc tttgatcgaa tatcgttttt tagggatcgt cataggaagt ttcatcggtt
     2101 taggtgttgc gtgggtaatg acggttggtt tgcaacatta tttaacggtt gttcgtcaaa
     2161 aattagaata gaaggacaaa tatatgtgcc aaaagaggtt atgacaagat ttttgtcaca
     2221 acctctaatt caaggtgttc aaaagccaga ttctcagcat taagtcaaat tcacacaaaa
     2281 atgtggaaag gaactttcaa aaaaatttta tatttattct atcaaaaaat tttgtttatg
     2341 atggtaactg aataaacttt cctgagatgg tcaatgcttt ccttgaaagt cttacagata
     2401 ttctttcttc atagaaagtt taagttttat agttagtgta caataaaagt atgtttatac
     2461 catatggtgt ccggataatc agtcatttaa acaatgaggt tcaaagatat gaaaagggga
     2521 aatttgatga agaaaataag caatgaaatc caaattctgg cagaaacttt aactcttccc
     2581 aaagtcgtta tagagcaaat gattgtacaa gcaaaaaaca tccttgatga ggtgtttgag
     2641 caatatagtc atgaactaat ggatcctaat aaagcaaagg cgactgcaaa gaaaatagac
     2701 aaagtctatg aagaggaacc ttttgcagca ttagctattt atctatatgc agcttctcaa
     2761 agttggaaaa aaatttatca accattgaag attccaagaa ctatctattt ggcaacaatg
     2821 aatgctttta ctagatttat tcatgaacat ttccaagtaa caggaagcta tcgctttgac
     2881 cgtggttttt ggatttggca ttacactagt ggcttgatct ttcggattgg tgaattggag
     2941 tacgaaatga catattttcc gaaagggtac acggatctaa gattagaagg aaagcagtgc
     3001 ctttctcttc atattccttc cgatgcagat ttatctcaga ataagataag agatagttac
     3061 gaaagtgcca ttcgtttttt tgaactttat tttcctgatt accattacca agtgatgtac
     3121 acagatactt ggttactatc acccaatctt actaaatggt tgaaaaaaga gtcaaaaatc
     3181 tgtctttttg cagccgatta tcgattatta tcagttgatg aacaggacga tagtggagtc
     3241 ccttggatct ttggacgagt agatgcccaa atacatgatt atccagaaag tacgagttta
     3301 cagcgacaag caaaagagca attgcttgca ggcgagcaca ttggctctgg cttaggtatt
     3361 cttacttcat aagtttagta cttcgaaata gtttaaaaga gcgtgagaca aaagtaaaga
     3421 acacttttgt ctcacgctct aaacacgtat aaacggcgga agcagaagca actccttcgg
     3481 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct
     3541 tggagttaaa cgcttctgtc ccagcctctt ttttagtgtt ctatcgaaca cacagtacgt
     3601 tcaataggta aactagctat aacaatagat attaaagtta acggacaaga gggccttttt
     3661 taggtagcta aaacgtaata atgaaaattt atttccagag ataggagtca atcagctagt
     3721 ctgatcgact gttttaacaa gttgactttc attttaactt ttgataccat ttaaaacaca
     3781 aatcgtaatt gtttcgattt gtgtttttta gcatgactac aatcaaagaa gaaagtgggt
     3841 cgtccatatg gaaaaaacag atatctcaag tgcataccgc cgcttgaaaa gcccaaatat
     3901 caaaacacga aaacgtgcgc tgaagatcat caaagatgtg aaacggaata gtgggaaaag
     3961 gtaagaagaa ggaaacttaa ttaaaaaaat agccgaaaaa cgtttttcgg ctattttcaa
     4021 taatcggttt ttgtgtaagg tttccgaaag aactgctgtt gattttccat ttttaacata
     4081 tgataaattg gtagaatctt tcttttcaaa ttgataccat tccctaattc cagttatata
     4141 gttaactaca gaaccacaaa gcacgtacgt ttataaaagt attatctgta gttatttttc
     4201 aattcccttt caacctctta ttttgaccag tagtattgat cactttacct tttaacacct
     4261 ttgttcgttt ttgaaacatt tttagtcaag aatggaaacg taactacata atcaaaggtt
     4321 ttgcgaaata tttcatgaaa tatttcatgt agaagcgagc aatacggttg caaataacca
     4381 ttatcgttta ataagcagtt acgaaagctc ccaatatctc taacgttcag ctcactccat
     4441 ttcttttctt caaaaaaatc agtgattcgt atctctttct atttgtcgaa aaagttaact
     4501 ttaaaaagta acgccgaaaa aatatgcaaa aaaataaaaa agcagttact attgctagaa
     4561 taacatcaag gaataataag ttttggtttt cagataatag tcgataagtt gtgtattgga
     4621 attttagata cagtaataaa gtatttttca tgaaattttg tgagaatcac tattacaagt
     4681 atctttaata aaattaatgg ttaaggagga acttaaagta gaatgtaaat gaatagttgt
     4741 agtcagtcga ttgtgatact agactcaaag ttgcaggaat aagtttttca atttgtgatt
     4801 ggaagataaa aaatgaaaaa gaagggcttt tttttatact ttgttgattg tagtgtttat
     4861 tttccctctg tttagccaag taacattttc tatgactcaa ccagtttcaa gtgaggaaca
     4921 tgataacctt tttcgtgcta cagaagagtt taagaaatat caggaaaata ttgttccgga
     4981 gactccatta gctagtgagc caattactga tattgatgga aaccaaatag gatggtatat
     5041 acagtacgaa gttatggtgg taaataatga ctcaatagta aaaaatacag taggcttaga
     5101 gctaacaccg attgaaaagg tgagttcatt gttaacgtat atttatactg atgaaagtga
     5161 cgagactgag atcattttaa cggattactc aaaaattgct actgataaaa agtatatatt
     5221 gtggatgtag acactagtga aatactttat gatatagaaa ttgatgaaaa tttactagat
     5281 gtagcacaag aaatcgatca tcaaaagcag gaagctattc gatatgctgg tagaaaaggg
     5341 aaaagaaaat atttattacg tgaatgtagc aaaagttaga gaagatgaaa atgagtggaa
     5401 agaattcaag agtcgctact caattaactc gactccgaca tttacagttt acagagaagg
     5461 atcgatagaa aaaactgttt tttggactaa agaaagtgga atgtctttag ctgaagtaga
     5521 agagtttttg gattatgtta gtatgcaaca gtaagggagt tcttattatg aaaaattttg
     5581 acacatatta tgttattgtt ttttcgatat ctttgctgtt aatattacta actttaatgc
     5641 agtataaaga gtatccagag tattttattt taacttttgt atatttagta agtagctaca
     5701 cacttctata taaattcaga agttcttcta gagtttctaa agtttgtttc ttaattagct
     5761 tattgattct ataatatttt tgatttatat aggaaattaa aaatattata gaatcaacac
     5821 tcagagaacg ggttggtttt taatagattt aataagtact gataatgaaa tttctcctgg
     5881 ttgggaaaac gaagttggtt accctgtaga agaatttttt caagattact ttgcggagta
     5941 tgccgatagg ataatgagag attacgtaac agataaaact caagaagtca tcaatcaatc
     6001 ccagtcatta aatgaattat ctgataaggc gaaagaagaa gcagttgcca ttatttcttc
     6061 agggattagt gactatattg atatgagtgg tgaaatcaat tatggcgata aagacaaaat
     6121 tgtacgcatg ataaaagctt ttatcaaaac ttttgatgtg aaggcagatc ttaagtttaa
     6181 tgatacttac ctagtaggaa aattaattaa tatccttggg acagagaaag atacggaaac
     6241 gtttatttcc tctttgtcta tgttgtttac agataagcat ttttcaactc agcttggtgg
     6301 agaggaacta gtggaaatct tttaaccatt acgcccagca ttaataaaag tatatcaaaa
     6361 aagtactcct gatgattttt aagattggtt tgagaaataa tgtgaaaaca ctatttttaa
     6421 tgttaattat agatagagat gaacgcgtca tatggttaaa agaatgaaaa agtcaaagat
     6481 acactgctat atttcactaa ggatatagca gtgtatcttt catgtcgttt cactggcagt
     6541 tttttataaa aggaggtgtg catttcagtt gcttttcttt ggtagttagt tgaatcgttt
     6601 aagaattaac ggatgtggca gacaggtgct ctgtccaaaa accagtaaaa tctttgatgg
     6661 ttccatcttt atttagctgt gcctgttcaa atactgtttt gtttttaccg aatggatcaa
     6721 ttgcaataat tgttccgatc cccgcacgtt tggcagcaag taatcctgag taagcatctt
     6781 cgataacaag acaatcagcc ggagctaagc tcagtttgtc tgccgcttta agaaaaatat
     6841 ccggttgcgg tttcccaggg aaagagccgt cgtcatagac aatcttgtcc cagtcaaacc
     6901 agcgggctaa atcgaaaata tcaaaataaa aagcaacatt ctctttgaca gtagccgtgg
     6961 caatcgttaa tggaatctgt tggtcagtca gctggtcaag agtcgcttca agcccttttg
     7021 tcaactgaag ctcgttttca ttttgcaagc aaagcatacg ataatagctt tctttttctt
     7081 ctgacaatac ggcgatctca gaggcggtca aatgctctga aatgaaatgt ttcaaaatct
     7141 ccgtattcgt ccgaccatga atatttttta aaatatcctc gtctgataaa ccatcttttg
     7201 tatgatcatg tatcatatgc agccaagcag cttcatgcag atgagagtcc aaaaacattg
     7261 ttccgttgaa atcaaatata atccctttca tagttacgct cctatagtgg tattttcggt
     7321 tgaatcagca atttgcagat cgacatattg tgcatagtgc tcttgaacct cccgcgagat
     7381 ctggcgatcc gtaatgagca gatcgaaatc atgcaaatta taaaacacat aaaaatcatc
     7441 tcgattgaat tttttattat caacgagtag atatttctta cgggaattat ttagagcgat
     7501 ctgctgtgct tctccttctt cggtactgta agtagagatc gcttcgttgt gaacgccatt
     7561 tgaactgata aatgcttttg taaactttag tcttcttaaa ttgtcgttgg tgatcggtcc
     7621 gacaaatgcg ccggtatttt tccggaaatc accgccaatc agtagaattt ctggtccatc
     7681 tgcttgagca agaatatcaa aaactggata attatttgta atgatccgaa ttttcttgtt
     7741 cagtaaatgc gtcgccaata gttcgattgt tgtacctggt cctaagaaaa tcgtttctcc
     7801 ctcgtgaatc aaggaggctg ctgtggcagc aatttctttt ttttcttgaa tctgcagagt
     7861 ggctttttca gtgtgagaaa gttcttgatc taaagtgtag gaaagacttt gagcccctcc
     7921 atggacacgc agcagcttgc ccgatttttc taattcatct aaatctctgc gaacggtcat
     7981 atcagaaaca tctaattgat tgatgatttc attaacggta aggattcctt ttttattgac
     8041 catttctacg atagtaagca atctttcttt tttcaacatt gtcttcacct ctaatttaag
     8101 gataatctat catataaacg gacaacagtc aatctaattc gaacaaaagt aaacatttag
     8161 ggtggttttt atgtttgtta caatagattt tattgctgtt ttctggtttt tatgattatt
     8221 tgtgtttgtt tttgttgaca aatgttttgg atgcgtttac aatgcaatca gttagaaaga
     8281 gcgaaaactg attatagatt tgaggagaga tgtacatgct taaattacca gaagatttta
     8341 tttttggcgg agccacagca gcctatcagg ttgaaggagc cactaaggaa ggtggcaaag
     8401 gcgctgttgc ttgggatgac tttttagagg aacaagggcg attcagtccc gatccggcaa
     8461 gtgattttta tcatcaatat gcaaaggaca ttgaattgtg tgaacgtttt ggtgtaaatg
     8521 gtctaagatt atccattgct tggagccgca tttttcctga tggagctggg aaaccaaatc
     8581 cagaaggaat cgctttttat catcgtgtgt tcgaagaatg taagaaaaga aacgtaacgc
     8641 cgtttgtgac gttgcatcat tttgataccc ctaaacgttt gtttgaccat ggagattttt
     8701 tgaatcgaga aacaatagaa gcatttgttt cctatgccat tttttgtttt catgaattca
     8761 aagaagtcaa ggtgtggagt acctttaatg aaatctatcc agttgcaacc aatcaatatt
     8821 tgttaggtgt tttcccacca ggaatcaaat atgattttac aaagatcgtc gcctgtcttc
     8881 ataatatgat ggttgctcat gcccgtgtag tgaactattt caaagaaaac gaacttccgg
     8941 gtgaaattgg tgtagttcac tcattagaga cgaaatatgc ggcaacagac gcgccggaag
     9001 ataagcatgc tgccttttta gacgatgcat tgtcgatccg tttcttatta gatgctacct
     9061 atttaggcta ttattcaact gaaaccttga ctgctcttga tgagatatgt gaagcaaatc
     9121 aggccagcta tcattttcct gaagaagatt tcgttgaatt gaaaaaagca tccacgcgta
     9181 atgactactt agggatcaat cactaccaat gccattttgt caaagcttac gatggagaaa
     9241 atgcaatcca tcataacggt acgggtgaaa aagggacctc tgtttataaa gtgaagggaa
     9301 tcggagaacg tatttataaa gaaggaattc ctcgaactga ttgggactgg ctgatttatc
     9361 cagaaggtct atatgacttg ttgctgcgaa ttaaaagcga ttacccacat tacaacaaaa
     9421 tctatatcac tgagaacggg atggggtata aagatcagtt tgaagatggc attattatgg
     9481 atcagccgag aatcgactat ttgagagtct atttggaatc cttaagcaag gcgataacag
     9541 ccggggtaaa tgtgaagggg tattttttgt ggtcgcttat ggatcttttc tcatggacaa
     9601 atgggtataa caaaaggtat ggcttgtttt atgttgattt tgaaacccag aagcgttacc
     9661 caaaagaatc agcttactgg tacaagttgg tcagtgaaac caaaacgatt atttaataag
     9721 tgataatgga ggaagaaaag atgaataaag aggaattaca aatgcttggt tttgagatcg
     9781 ttgcatattc aggcgacgct cgcagtacat tattgaaatt attgaaagaa gtaagacaag
     9841 gaaactttga acatgttgat tcggcgttga aagaagccga cgaaaattta acccttgcac
     9901 ataattcgca aacaaaaatt ttagcggaag aagcatctgg gaaagagatg gagatgggat
     9961 tcatttttat ccatgggcag gatcatttaa tgaccacttt attgctgaga gatctgattc
    10021 aagactttat tgtactgtac agacagaatc aaggatagga gaagaacgct atggatggaa
    10081 tcattaaaca aatcgaaaaa gggaaaccat tttttgaaaa aatctcacgt aatagttatt
    10141 taggagccgt tcgtgacgga tttttaacag cgatgccagc tattttattt tcaagcattt
    10201 tcattttgat tgctgcggtt cctgagattt ttggttacca atggcctgaa tctgtctcca
    10261 catggctatg gaaagtctat aattattcga tgggtgttgt agggttactc gtttcagcaa
    10321 ccactgctcg ctgcttggct gattcgatga atcgtcgctt accgaaaaac aaagtaatca
    10381 acaccacctc tgtgatgctg gcctctgtgg taagtttcct gttgttaagc gtctctccga
    10441 ttgaaggtgg attttcaacg gaatatatgg ggacaaaggg actactggct tcctttgtcg
    10501 ctgcattttt aacagttaat ttatataagt tttgtgtgct gaaagatatt accattaaaa
    10561 tgcctaaaga agttcctgga acgatttcgc aaaccttccg agatattttt cctttctctt
    10621 tttcagtatt tgcggccgtt ttaattgatt taggcattcg acaaatcttc caaatctcat
    10681 ttgcagaagc aatcattacg gtgctgcagc cgctatttac agcagctgac gggtacttag
    10741 gaatcgctat tatctgggga gcgatggcgc tgttttggtt tgtcggtgtt catggaccgt
    10801 cgatcgtgga gccggcaatt gcggcaatta tctatgccaa tgtggaaacc aatctgcaat
    10861 tgttcaattc cggtgaacaa gcttctaaag tactgacggt gggtttaggg aattttgtag
    10921 gaactatggg aggaactggg gcaacattgg ttgttccttt tatcttccta ctctttgcta
    10981 agtctaagca gttgaaggca gttgggaaag cttcctttat tccagtaagt ttcgctgtca
    11041 acgaaccatt gctatttgcg gcacccatga ttttgaaccc ttattttttt attccatttt
    11101 tgttaacacc tgttgtaaac gtttgcctgt tcaagttttt tgtcgatgta ttgggcatga
    11161 acagctttat gtacgttttg ccttgggcaa ctccagcacc gatcggtttg gttctaggaa
    11221 cgggcatggg tatcttagct tttgttctag cagcggttct aatcgtcgtt gacttcctga
    11281 tctatctacc attttgcaaa gcatacgatg ctgtcttagt agagaaagaa gcacaaaaag
    11341 cagaggtgat cgcaaccgag gaaggtgctt ctgccgatgt acgtgaggaa gtacctgtgg
    11401 cagcgagtca agttatcagc gatgcaaata aagaaatcaa tgtgttggta ctttgtgctg
    11461 gcgcagggac aagtgcgatg ttagctaatg ctttaaaaaa aggtgcatct gaatcgaaag
    11521 caccgatcag tgcaatggcg ggtgcttatg gttctcatta cgaaatgctg caggattttg
    11581 atatggtggt cttagcaccg caagtcaatt cttactatga tgatatcaaa gaagacaccg
    11641 atcgcttagg aatcaagctg gttgcgacaa aaggagcaga atatatcgga ttaacgagag
    11701 atcctgaaaa agctgttcag tttattctga accaatttca ataaaggagg agccataatg
    11761 aaaatgggaa tttggttgcg taaagctgtt ttatttgcag ctgtgttagg ggctttgggg
    11821 gctgtttcaa aaactgttga agcatctgcc agcgaattta ttcgcggagc agatatttcg
    11881 atcctgtcag atatggaaaa atctggtgca aaatattatg aagacgatat ttcaaaagat
    11941 gccttagaga ttttaaaaaa taatggtgtc aactatgttc gactgcgttt gtggcaggat
    12001 ccttataata gtaatggaga aagttatgga gcagggacaa atgatctgga aacgacgatt
    12061 gaccttgcaa aacgagcaaa aaatctggga cttaaggtgc tgctggattt tcactacagt
    12121 gatttttggg ttgatcctgg gaaacagaat cttcctaaag catggcaagg tctgaccttt
    12181 gaagaaatga atacggcatt gtacgactat acaaagaacg ttctgtcgga aatgaagcag
    12241 ctggacgttt atcctgatat ggttcagatc ggcaatgaac tgaatagcgg aatgctctgg
    12301 ccttatggca agtcttgggg agaaggcggg ggagaatttg atcgattggc tgcttttttg
    12361 aagtctggta tccaagctgt tcgagacact caacctaaaa caactccagt aatgctccac
    12421 ttagctgatg gtggcgatac aggagcattt acttggtggt ttgatgaaat cacgagtcga
    12481 ggtgtgtcat ttgatttaat tggagtgtcg tattatccgt attggcacgg ttcaatgaat
    12541 gaacttcaaa ccaatatgaa tgcgatcagc caacggtatg gtaaagaagt gatcgtagtt
    12601 gaaacagctt atgggcatac aacagcgaat gccgatacta tgccaaatgc ttttggtgaa
    12661 gccgaagcag ctgcgggggg atatgaacca acaccgacag gacaagcaga gtatttgctg
    12721 gatcttgccg atcggattca ggcagtaccg aataatcgcg gggcgggctt cttctattgg
    12781 gaacctcttt ggtacaacgg aaatgtgagt tgggcaacac aagcaggtat gaattatctc
    12841 agtgttcaat ccactatggg aaacgaatgg gacaaccaag cgatgtttga ttttgctgga
    12901 aacgccttgc caagcttgcg tgcgtttaaa caagcagggg cgcaaataaa tctagttaaa
    12961 aatgcaagtt tcgaaagcga tggaccaacg accagtcctt ccaattggca aacctggttt
    13021 caacaaggaa ccgctaaggg tacgatcaaa acggaagcgg gcactttttt tggggactac
    13081 aaactaactt tttggcagga tcaagcatac gaggcatcag cttatcaaaa tgttagtggc
    13141 ataagcaaag gaacttacac attgagtgcc tatgtaatgt ctgggggaga gtttgatact
    13201 aatcagttat atatcaaaaa ttatggtgga gcggaactaa atactgcggt tgttaaaaca
    13261 agtgaatgga caaaaattac aatcaaagac attccaatta caacaggtgt ttgtgaaatt
    13321 ggggtttata gcaaggcttc aggaaatgct tggacgaacg ttgattttgt ttcattggtg
    13381 aaacaataga ctgcggatcg tttcgattca agatcggagg ttcccttcag ccacatcgtt
    13441 agcgtagaag gcaggaatcg aacctgcacc tcgcctttgc caaaaataac cagaaacgat
    13501 ttccagtcat ttttaccaaa acgagtaaag caccagactt catctacact ttgtattatg
    13561 ctaaagagag ttcaacgatt tcgtaagaag caatgaaaaa attgcaaaaa gttgtgcaga
    13621 taacataaag tttgtttaag aaagggtaac cttagaattc cgtcgtgaat atgatttgag
    13681 cacttagatg gatagaaaaa agttctcgga aaacagttcg tttttcgaga acttcttttt
    13741 atgataagaa tgaaacaaat taacttatat tatagtctct tttggtaggg aaccatctta
    13801 tttttaatga aaatcaagca ttttagctat tgaagaatgt tgatttatag ggattccccc
    13861 tccatattat gttggctctt tattcccact ctgttttcaa cgtaaagtgt ataaaacaga
    13921 atgcgatact atcaagggag ttaaaacaat atacagaaca gtaaaacact ataaataaaa
    13981 ataaaagtgc aataaaagtg caatttttgc acctaatcat actctgttta tatatgaaaa
    14041 ctagattctg aatccaatat ttggttaacg agaggcgttc gaatttgaac gtcttttata
    14101 tattactttc aaataaatat gaggtagaat actatctatt ttctttttaa cccaattgtt
    14161 ataatggaga gtgtaaaata ttttgtgtaa atagaaaaaa ggaagtccct tctgtagaat
    14221 agagttacca caacacattc acagaagaga ggacttccct atgaacgatt ttactacaga
    14281 aattctaaag actctagcga acaaaggcga tttgaatgaa ttattccgtg tccatttgga
    14341 gaaagcagtc aatacgcttc tcaaaacgga gttaacggct ttcctagatt acgaaaagta
    14401 tgatcgcatt ggttttaaca cgggtaattc tcgtaacggc tcctatgacc gtacggtcaa
    14461 gaccgagtat ggggaacttc atctccagat tccgcgcgac cgcaatggtg agttcaagca
    14521 acagactgtt cctgcttata gacggacgaa tgacacgtta gaggagaccg tcattcacct
    14581 cttccgaaaa ggtattacca tgtcggaaat cgcagacttg attgagaaaa tgtatgggca
    14641 ttactacacg ccccaaacca tgtccaatat aacaaaatca tttacagaag aggtaacggc
    14701 gtttaatggg cgggagcttc atgaccgtta tgctgctatt tatatggacg caacgtatat
    14761 tccgttaaag cggaaaaccg tcgccaagga agctattcat atcgcagttg gcattcgccc
    14821 ggacggatca aaggaagtat tgagctatgc gattgcaccg actgaatcca tcacgatttg
    14881 ggaggaaatt ttattggacc ttcaagagcg cggtttgaaa aatgtcctcc tgttcatcac
    14941 ggatggctta aaggggatgg taggagcgat tagtcggttc tatcccaaag ctcgttttca
    15001 acattgttgt gtacacgttt cccgtaatat cagtcataaa gtgcgtgtcg atgatcgtaa
    15061 ggaagtctgt gatgatttta aaatggtgta tcaagcctca tctaaagagg tggcgttgga
    15121 agcacgtggt acttttgcgg aaaaatggaa aaccagctat ccaaaagtgg ttgaatcgat
    15181 tctttcgaac gatcacttgc tcactttcta tgatttcccc ttggccatac gcaagagtat
    15241 ttattctacg aacttgattg aatcctttaa taaacaaatc aagaaataca gccaccgcaa
    15301 ggaacagttc caaaatgaag agtcgatgga acgtttctta gtctcgtctt ttgatactta
    15361 caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa caggccgaag gcgagctcga
    15421 acaaatgcta agccaactga ttgagaatta gaaacaatct gcagtaggga agaatcattt
    15481 acacaaaatt attgacgctc ccttataatg agaactttta ctaacataat ttatgataaa
    15541 cttactatat aatcatatta attaaatagt taggagatct gcttatgttt atatctactc
    15601 ttcaaattcg aaattttaga aattatgaat ccgaaatctt tcgattcgat aatgagacaa
    15661 atactattat aggtgagaat gattcaggga aaaccaatgc tcttac
//
LOCUS       DARBDN010000063        15255 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000063 DARBDN010000000
VERSION     DARBDN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.063"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..353
                     /locus_tag="SCH06_001919"
     CDS             <1..353
                     /locus_tag="SCH06_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1078473.1"
                     /translation="QTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTI
                     SSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNF
                     RARIYLQQGLIFEN"
     gene            complement(736..1464)
                     /locus_tag="SCH06_001920"
     CDS             complement(736..1464)
                     /locus_tag="SCH06_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HEG1078474.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1442..3016)
                     /locus_tag="SCH06_001921"
     CDS             complement(1442..3016)
                     /locus_tag="SCH06_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEG1078475.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            3245..4183
                     /locus_tag="SCH06_001922"
     CDS             3245..4183
                     /locus_tag="SCH06_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1078476.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            4195..5106
                     /locus_tag="SCH06_001923"
     CDS             4195..5106
                     /locus_tag="SCH06_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1078477.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            5130..6602
                     /locus_tag="SCH06_001924"
     CDS             5130..6602
                     /locus_tag="SCH06_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEG1078478.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6653..7264
                     /locus_tag="SCH06_001925"
     CDS             6653..7264
                     /locus_tag="SCH06_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEG1078479.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            7294..9207
                     /locus_tag="SCH06_001926"
     CDS             7294..9207
                     /locus_tag="SCH06_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HEG1078480.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            9335..12316
                     /locus_tag="SCH06_001927"
     CDS             9335..12316
                     /locus_tag="SCH06_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HEG1078481.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            12313..13974
                     /locus_tag="SCH06_001928"
     CDS             12313..13974
                     /locus_tag="SCH06_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEG1078482.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            14014..14946
                     /locus_tag="SCH06_001929"
     CDS             14014..14946
                     /locus_tag="SCH06_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEG1078483.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4955 a         2424 c         3060 g         4816 t
ORIGIN      
        1 gtcaaacaga aatcgttgat gagctgttaa gctacaacga agaattgcga actgcgtatc
       61 atttttgtca attattacgc tattatttcg ttaaacgagg tacggaaggc tttcaagaaa
      121 cccttaaaac aatttcatct acgttacctc agtcgtttaa aaagaaattc acgatcttcc
      181 attgctacca atcgggtatt tcaaatgcct ttaaggtgtc ccactcaaac ggcgtcactg
      241 aggggctgaa taacaagatc aagctgatta aacgaattgc gtttggttat cgcaactttt
      301 ataactttcg ggcacggatc tatttacaac aaggtctgat ctttgaaaac taaaaaaata
      361 tgcggcgcac agaacgcgcc gcatatcgga ctaagtttta ttcaaatttg tcttcaccaa
      421 cacgatttga cgaagagcct atttaaataa ctacatccat ttattctatc ttctaaaata
      481 gcctttttca tttcagttaa atagttcagc gccatttttg cactcgactt gcatagtagt
      541 tttttccata ttcctcaacc tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta
      601 tgctcaactg gatctgatta aatattctaa tgtatttttc tctaccatca ttaaatggtt
      661 aatagccaaa aatcaccact tttcaatggc tccttgttgt ataagtataa ctagaagatg
      721 aacacgtctg agaaattata gaagcttttt acggtaatta ctggggctgt gtccagtagt
      781 ttttttgaag agaacagaaa aatagctcac gtgatctatt cctacttttt gactaatttc
      841 atcaatagat aagaatgtgt ctttcagtag agcacttgct cttttgattc gaaagtctag
      901 caagtaatca tgaaaggaat aacctgtttc ttttttgaag gcccgtccta aataagcggg
      961 atggtaatgg aattgtgtag ctacatcttt gagcgtaagc ttttcactat aattgttttg
     1021 aacgtaatca atcacttgtt gaattgactc attaaaagaa tcatcagtta gagagttttg
     1081 attagctgct gatttacgca ttttttcttc ttgtactaac ttaactaaat aaggaaaatc
     1141 aatgggtttc gttatgtaac ttttaataga taaatcaatc cccttttttg catactgaaa
     1201 attttggtgg gcactaatga caatactagt aaagtagcga ttggatgttt gttgcaaaga
     1261 ttcgattaat tcgagtccag aaattttccc catcgtaata tctgtgataa gtaaatcaaa
     1321 gcgctggttt tgcaggtttt taaatgcttc gtctccgtct gtgtagcagt gatcgataat
     1381 gatgtcgggg actttcttca aaagataatg ccttatgcct tctacaattg tacaatcatc
     1441 gtcaacaatt gcaattctca acatgcatat tccccccttt ttgtattttg atagtaatcg
     1501 ttgttccgac gtgtagttgg ctttctataa caaaacgtgt atctccagga tagagatgct
     1561 ttatacgtcg aaaagaattt gagatgccga tattctcact ataaggaata tcatcattaa
     1621 gtttttgttg aatatgctcc agcttgtctt ggtccattcc tttcccattt tcaacgattt
     1681 ttaacacata atggttggtt gtttcagttg catagacagt caaacgattt tccttttttg
     1741 atgaatcgaa gccgtgttta atataatttt caacaaatgg ctgtaaagaa agttttggta
     1801 acattaattg atcaatatga tcaatcagct gatagtcaaa gttatgtcga taacgacgtt
     1861 gatgtagttg caaggagagg tcgatattaa ttaattcctc tttcaaatca attatgtcgg
     1921 gctgatatgt attattgcga tacaacttgc tcaataaata tatactgtcg ctgatttctt
     1981 cgtcatcatt caatatggca gtcattcgaa taaattccaa attattaaat agaaaatgag
     2041 gctcgatttg atattgaagt gctgcatact ttgcttcttg cttcaaccaa ttattttcat
     2101 aaagtgtttt ttgatatgta gcattatcta aataaaactg attgatatgc atagcgattt
     2161 ctttcaaatc accgactttg ttttcgatat tgattgactt gtagtctcct gtagatgaat
     2221 gatttaagga agtaatgatt tcctgatact gctggatata gttacgaaaa cttctattta
     2281 ataattgatg aatagcaaga ataaacaaac tcattaataa gaaaatcatg attgccagac
     2341 ctaataaggt ttgtgacgaa taatttggat tttcatatac ttgtaatgtg tggttaccga
     2401 tagctatctg ttgcgttttt ttccatttag aaggcgagat gtcttcagat aaattgacgg
     2461 aatcaatacc attagacaaa gaataattgt aatgtgttgg aaagagactc ttttttagcg
     2521 cgttgatcga aacgtctaga atcaatgtag catcgggcat gtcctcacta atgaaactta
     2581 atgaacgaat aaaagaaatt ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt
     2641 cgtaatctaa tgagatagat atatttttaa cttcatcatc ttgcacaagt ttttttaagt
     2701 tatctactaa ataggtaggg gagcgatcct ttgacaaaat atcttccatg tattcagcag
     2761 gtgatgagag gtagtagtca ttaaggtttt cttggaaatc ataattttga tagatctctg
     2821 tcacgatacc ggagagaata cgattatatg tttccatata gtgggtgatt tgctgaatgt
     2881 tttgcaggtt ttgatttttt tctttttcaa tcacattgat ataggaaaag aacaatgtga
     2941 aacaggcaag taaagtaata aaaaaaatca atatgtatgt aaaacgcata ataacttttg
     3001 ataaatcgtt tttcattcaa agtcctcatt ttgataatct ctaattttat gaatcattat
     3061 agcacatatt acaagtgatg taaacgcttt gcaaacaggg ctacttatga ttgtgaatac
     3121 agtttccgtt taaaaactat tctattgtag aggtttaata aactaaaaat aatgtataaa
     3181 aaattaatgt aagcgattaa ccaagtgggt ataatcaagg aaacgctgag agaggagaga
     3241 caaaatgaag ctaaagaaag ggttattagg aaatctaaaa aaaaaccgag cattgtttat
     3301 tatgctttta ccaggtgcgt tatggttatt tatattttgc tatataccaa tgtttggagt
     3361 tgtaatcgct tttaaagatt tcagaatttc atcaagggga ttctttacaa gtttgttcaa
     3421 cagtccttgg gttggctggg aaaatttcaa atatctcttt gcttcgcaag atgcttggat
     3481 cattactcgc aatacggttg tttataacgt tgtaggtatt ttgctaagta ctttttgtac
     3541 agtgtcatta gcaatcattc tgagccaaat ggcgaacaaa cggttattga aaaagatgca
     3601 gacatttatg atttttccta attttttatc atgggtagtc atcagttact ttgtttacgc
     3661 atttttgagt acggataaag gattaattaa tattttacta agcaattttg gtgtggaacc
     3721 cataaattgg tatagtgaac cgaagtactg gccttttatt attgttttta cgagtttatg
     3781 gaaaggcgta ggctatggat ccatcattta ttacgcgtca attatgggga tcgatactag
     3841 ttattatgaa gctgctttag ttgatggtgc cagtaaatgg caacagataa ggaatgtagt
     3901 cttgccacat ttaagatcga ttattgtcat tatgttgatt ttgtctgttg gtagtatttt
     3961 tcgagctgat tttggattgt tttatcaatt gccaagaaat tcgggggctc tttatgatgt
     4021 gacgaatgta ttagatactt atgtctaccg tggattaatg aatagcggag atatcggaat
     4081 gtctacggca gcgggattat atcagtcatc agttggcttt gtcttgattt tgattactaa
     4141 taagatagtc aacaagttag atcctagttc agcactattt taggaggaat caaaatgata
     4201 tcaaaattaa aacggcagat gtacttttcg ctgccagtcg aacggttttt cacaatatta
     4261 ctaatcttat ttactcttag ctgtattttt ccctttattt tcgtaatcgt catttcatta
     4321 acagatgaaa aagcattaca actcaacggt tacgaattat tgccggctca atggagcact
     4381 gatgcatatc aatacttaat acaagatggc ggacagttac ttcggtcatt aggcgttaca
     4441 attatgatta cagtgattgg aacgttgatt actgttttta tgacgggaac ctatgcttat
     4501 gttttatcaa gagcctcttt cccttaccgg aagttcttta ctttttatct tttttttacc
     4561 atgttatttg cgggagggat ggttccttct tacttagtga tgacgaagat gcttggctta
     4621 aaaaatacaa tttgggcttt gattctacct cttgctttta gcccatacaa tgtcattatt
     4681 ttaaggacat tctttaagaa gtcgattcca gaatcgatta tcgaatccgc taaaatggat
     4741 ggctgtagtg agtttcgagt ttttttccaa atcgttttgc ctttagcgat cccaggggtt
     4801 gcaacaatag gtttattttc aagcttaggt tattggaatg actggttcaa cgcattgctg
     4861 tatattgaca ccaacaaatt gattccattg caatatttgt taatgaagat tcaaaattca
     4921 atggaattct tagcaaataa taatgacatt acattagcgc agcaacaagc aattcaaaat
     4981 agccttcctc aagaatcaac acgaatggca atggtcgtag tagctacttt accgattgca
     5041 attgtttatc cgttcttcca aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa
     5101 gaataaaaaa gaataggaga tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg
     5161 gtggtgcttc tgtactaacc cttggcctat taggtgcttg tggtagcagt aatggcgaag
     5221 caaataatga aacaggaacc acaaaagtta cttggtatca ggttggagaa gaacccaaag
     5281 attttgatga ggtcatgaca aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt
     5341 tggatatgcg gctgattccg gacggggatt atcagcaaaa gcttggtgtg atgatcaatt
     5401 caggagaaga atatgatatt tgtttcgtca atggcacaga ttatgtgaat tatgggaaca
     5461 aaggtgcttt cattagtctc aacgatcatt tggataaaga gttgaaagat tatgcagctg
     5521 aattgaatga aggatttatt gaaggtgggg caattaatgg cgaaacttat ggattgccag
     5581 tcaataacga tattgccaca acggaatatt ggacctttaa taaagatttg gtagatcaat
     5641 accaattgga tgtagagaat gttgaaggtg tagaaacatt ggctccagta ttagaaaagt
     5701 ttgcagaaaa aaatactgat acgaatatta cgccaatcgg tatgacccgt accagtgtct
     5761 gtattcctta tgacaatatt atcggtggtg gtgtaccgct agcggttgca tttgaaggcg
     5821 atacacaaac agttgttaat acttatgaga ctccagaaat gatgacttat ttgaaggcta
     5881 tgcatgagtt ttataaaaaa ggatatattt tgaaagatgc agccactgtt acgacagatc
     5941 catttcgaat tgatagtaaa aactggtttt taggtcgtaa ctcaagtggt tatcaaccat
     6001 tagcacaaaa aaaattagaa gctctagcgg gacatggatt aattttaaaa ccagctggaa
     6061 aagcttttaa aacgactgga tttgcaagag tggcaatgca tgcggtatct gcttcaagta
     6121 aacatccgga agcagccttg aaattgttga attatgtgaa taccaatcaa gaagtagcgg
     6181 atttaatggt ttatggaatt gaaggaaaac actatgatcg caatgaagat ggttcgatta
     6241 ctttaacaaa ctctgatgat tattatcaag gcgcttgggc attggtaaat acttatctag
     6301 tttcaaaaac ttcaccgatt acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt
     6361 ttcaaaatga agcaccgatg tctcctattt taggtttctc ttttgacgct tctgattttc
     6421 gaacagaaat tgcaagtgta caaaatatcg tgtcacaata tgaagtactt ttaagctcgg
     6481 gaacagttga ccctgaacaa tatgtaccag agttgttaga aaaactagaa aaagctggat
     6541 tggataaaat tcaggcatct gctcaagaac aatacgatga atggcgaaaa tctaacaaat
     6601 aattttttac taaatgaaaa gaatagacta agcagttagt ggggggattc aaatgaacga
     6661 aaacaaatgg accaaaggat ttaattgggt ttttcaattg ttgttactaa actttactta
     6721 ttttatacta atttgtttag gatttggaat tttaggtttt ttccctgcta cgatagcttt
     6781 gattgctggc gttgtgaatc gaaaaaaata tggcttgcaa gagtctgtga agttcatgag
     6841 taaaatctat aagaaaaatt ttgttagata taatctatat tgctggtcag caactttgtt
     6901 gttggccggc aatattacta cgatctggct ttgttggcag caaagcgcac cattgtttta
     6961 tttattaagt acattattat cggtaattac actgttccta gtctttgcaa tgttgaattg
     7021 ggtcgtgatc aaaagtcttg ggttgtggat gatgggagac cgactgattg actatttgct
     7081 tttcacagca acgatgttgc caacggtagt catgcaaggc ttggtgcttg gaatttattt
     7141 ccgaatattg atgattttgc ctgtgatttt tctgtttggc ggaacagctg taacggtaat
     7201 attgattagt aaattaactg aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca
     7261 ctaatttttt cacaaaaagg agtatttctt tctatgaagt taactgataa acaagtagct
     7321 aatatagcct ttatccagca acttgagatt ccattgacac aaaaagatga agaacaaata
     7381 gacttgattt ttactgacac aaaggctaat gtgcgacaaa tcaagattac taaaaatgag
     7441 cagcaacgaa tttgcttgtc ttattcacat gaagacttgc tgtatcgagg attgtttatc
     7501 tgccttccac gttttttagc tcaaggagga gagatgccat acattgaaga aacctcgatc
     7561 attgagacca gttattcatt agatgcttct cgtaatggcg tgatgaataa agagactcta
     7621 aaaaaattca tttcttactt agcgttgatg gggtacaaca cattgtatat ttacacagaa
     7681 gatacctatg aagtagaaga ccttccatat tttggttacc ttcgcggagc gtatacaaaa
     7741 gaagaagtga atgaaattgt tgaatttgct tctggttttg gcatagaagt agttccatcg
     7801 atccagaccc ttgctcactt gacccaattt ttgaagtggt atgctcaaca agaactgatg
     7861 gatgatcaaa atactctact gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg
     7921 attattgcct gcaaagaaat gtatcagaca gagcgtattc atttgggaat ggatgaagcc
     7981 tatcaagcag gtctgggacg atatttaagc ctgtatgggt attgtgatcg gacaacttta
     8041 atgattcaac atatggaccg tgtgttatca attgttgata aatataagat gaaaccaatg
     8101 atttggagtg atttcattta taagctatta gatgaaaccg gtaaagatag gtattacaat
     8161 cctgatttta aactcaaagc attagcagct aaaggattac cagcaggatt aacctatgtt
     8221 cattgggact atggttcaga tgaagtttcc tcctatgaga aagtaattga taaccatttg
     8281 aaattttgtg acattgatca ttacgtttta gctagtggtg cccatatctg ggggagacta
     8341 gccccgaatc atgggaaaac agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat
     8401 aaaggtgtac gttctgtgat gttaactact tggggagatg aagggcagga aacagagcat
     8461 tggcattcct taattggggc attaaaatta gcagattatg tctattctga agaagagtgg
     8521 aatgattttg aggaaatcta cgatcgttta ttaggaacag gtagttatca attaatgtcc
     8581 gaattacgat atttcgatga agtggatacc attacaaata acaacttaca aatggcttcc
     8641 gtgagtaaac tgctactttg gcaagatccg ttagttggta tatatgactt tcatgtagcc
     8701 gctcataaca aaattgccac tagaacaatt ggtacttatt atcatgagtt agctcagaaa
     8761 ttagatatga ataaaaattg gaatccaaaa caaccaattt taacaactat tcgtcaacga
     8821 tatatacttt tagctgaaat tttagcacaa aaggcagaac taggcatcta tttacaacac
     8881 tgctgtctgg tagaagacct tgcaggatta atggaattag cgaatcggtg tgaagcacta
     8941 gccaatcgag taaatgaatt ggcatctatt catgaaataa tttggtatca aacatacaaa
     9001 acctatggtt gggaagtatt agaacaacga tatgctgcat tagctcatcg tctgaaaacc
     9061 gttgcgcgtc gtattaaaaa tcatcttcag gggcaagatg ccctagagga gcttttggaa
     9121 gaacgattac cgttttgtca atatcaagtg ccgcttgaaa tttctggctt taattatcgg
     9181 caaagctcgg tgtcaggcta caattaacga aggaatcttc ccgttgaacg gaccacttgc
     9241 tcatctaatg ggaaagtggt tcgttttcta ttcataagta gcttaccact aactctttta
     9301 ttaagaagag aaaaaaagta ggaagtgaga aaatatgtta tcggactatt atcaaaatct
     9361 gtcagttata agtgtcaata cagaaccatt acgtaattat tatattcctt atgcaagtaa
     9421 agaagaagca aaacaagagt tagaaaggga aaaaacgagc cagtttatcg atctcaatgg
     9481 tacatgggat tttcagtatt atccttctgt ccaacagtta ccggaaaatt tttttcaaga
     9541 ggcctttact gaaagctatg atagaatttc tgttcctgga gtttggcaaa cagagggatt
     9601 tgacttacct cagtatatca atgtatctta tccaattcct tttgatccgc cttatgtacc
     9661 taatgatacc ccttgtggtg tatatcggcg tcagtttcaa attgagcaaa cagatgcacg
     9721 cttttactta aatctagaag gagcagatag taattgtttt gtttggataa atagaaactt
     9781 tgtaggctat gaccaagtga gtcatagtac atctgaattt gatgtgacca agtatttaca
     9841 ggttggggtt aatgaaattc aaattctagt gatgaagtgg tgtgatggta cctactttga
     9901 agatcaggat aagtggcgaa tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc
     9961 aactatgcat ctgacaagtt atcaactacg gacgttgact gatcctaaaa aaggaagcgg
    10021 aacattaatg gtttcttttc aacgatttac tcctattgaa gtatcgttac ctatttctta
    10081 cgaattattc catcctgatg gacgtctcat agcgaaaggg gagtgttact cggaacaaca
    10141 aataaatttg gatgttgaag attgcctttt ttggacagca gaaacgccta aattatatac
    10201 attactttta acatgtaatg gtgaatattt taaagaaaaa gttggctttc gagcactgac
    10261 gatcaagaat cgtaagttat tgctgaacgg aacacctatt aaattatatg gagtcaacta
    10321 tcatgacgtg aatcagcaag gcacgccagt gatgacccga gagcagttac gtgcagattt
    10381 gttattaatg aaaaaattaa atgtgaatac tgtacgaacg gcacattacc ctaaatcacc
    10441 agatttttat gaattggcgg atgagattgg tctgtatgta atcaatgaag cagatttgga
    10501 gtgtcatggt gtggttaatc tatatgatac tgaagcgaat tatcaactaa ttgctaatga
    10561 tccgacattc gaaaagccga ttatggaccg agtgatccgt tctattcttc cttatcaaaa
    10621 tcgaagctct atcattatgt ggtctatggg gaatgaatct ggttatggag taaattttga
    10681 aaaagctcaa gctttagcac ggaaattgga tgattcacgg ttgattcata atgaacgctc
    10741 gattgaacca gttattgacc aagtgaatga ttttagtaac ttggatgtta ttagtcaaat
    10801 gtatccccca ctggaagatg ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt
    10861 ttttatgtgt gaatatagcc acgctatggg caacggtcct ggagatctta aaacgtactt
    10921 cgatttgatt caacagtatg attcctttct tggcggttgt gtctgggagt ggactgatca
    10981 tgcaatcaat agaggaactt tagaaacgcc atcttattta tacggtggtg attttggtga
    11041 aaaatatcac gacggcaatt tttgcgtaga tggtttattg accccagatc ggcaattaac
    11101 agtaggtgca ttggagtacc gtaatattca ttcgcctatt caactgattg ctgtagatga
    11161 ggagctgcaa gaagtaacct tgagcaatat aactgctttt acagccggtt cagcatttaa
    11221 cctttctctt gaatggtata tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt
    11281 catacttgag cctggcaaaa gttgttcatt gcccatcaca gtacctacaa cgattcatgg
    11341 tgctcatacg gttgctgttt cgctatctgt ttataaaaat gatgagcttt atggacagca
    11401 acagctcttt cttaaaaaag aaaaaatgag attgccaaga actgctcatc ataatgatgc
    11461 accacaaatt tcagtaaaag gcacagagct gataatcaaa ggagaatcct ttatttatat
    11521 atatcaatta gcaaaagctg cgttcacttc tgtaaagatc aatcaaaagg aacttttgga
    11581 acgtcctact caattttcaa tttggcgtgc accaacggat aatgatcgta acttagtaaa
    11641 caaatggaaa gcagctggat atgctgaaat gtctttagaa atcagaaaaa aagactggaa
    11701 attcgtagat gatcatctcc tgatcgaaac gtcttatcga ggagttattc caggattaca
    11761 gccaattttt acaatgcaca tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa
    11821 agtatcagtg gagaaaaatc cgatttttcc agatttccct cgctttggga tggactggcc
    11881 gttgaatgat actttttcga aggtttctta ttgtggctat gggccgtatg aaagttatcc
    11941 tgataagcac tatgctgcga tgtttggtat ttatgagatg gagattgagg aatttgatca
    12001 gccatatatc aaaccacaag aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa
    12061 aaatcatcaa ggatctacca tgacggttta tggaaactct aatttttctg ctctgcctta
    12121 tagtcaagct caattaaccg aaaagtcaca ccattatgaa ttaataaaag aaaatagaac
    12181 ttggttcaat ttaagttata aacaaaatgg tatcggctca cacagttgcg gtccttattt
    12241 agaagatcgt ttccgtttta tggaagatac ttttgactgg aatatagtga ttactttcaa
    12301 aggagaaaat agatgaaaga aacaaagatc aatcaagtca aaaaaaaatt atctcgttat
    12361 caagaagttg tttatcgaaa ccattgctta aaatggtcaa aaaataagct gaatgttcgt
    12421 tttaatggat tattttatcg tttcgaacag ttagaagaag tctggaaacc ggtaacgaat
    12481 ttccaatcat gtcctgtaca gctcataaat gatccaaaag aaacatacga tttatgtata
    12541 acacaccttt ataaccagca tttgaaaaat gacggatttt atttaaaggt tactaatgac
    12601 aatcaactta cgattgaatc agcaaacctt cgagggtttc aatatgctat ggaagcctta
    12661 ttagagagtt ttttttcggt aggagatcaa ttattattac cggaattgat tctgaaacat
    12721 gaaccatcag tgaaaattcg aggaatcatt gaagggtttt atggtatccc ctggacacat
    12781 gaaatgcgcc tctctctttt ttcatatatg aaagataacc aattgaatac ttttatgtat
    12841 gcccctaaag atgatgaatt attacgtaaa aaatggcgtg aactctacga tgcgcaagaa
    12901 ttagacaaat ttaaggagct tttatctgct gctgaggcta gcaatatcga tttttggtac
    12961 ttaattagtc ctggaaatga tattgatatt acgtgtgaag aagacattca agttcttctg
    13021 aaaaagttag aacaactgat tgagcttggc gtatttcaat ttggtctatt aatggatgat
    13081 attgactatc aattaaaagg tgctgctaaa cgccgttttc gagagccagc attcgctcat
    13141 gcctatttag tgaatcgagt agaggaatat cttagcactc ggttgtccaa tcatgaatta
    13201 gtcatttgtc ctacagaata tgataatcgt catggttctc gctatttagc aacgttaagt
    13261 caagaaatac cagaacaatt accgttcttt tggactggcc caagcacgtt agcggcgtca
    13321 atttctacag aagagctgca ggaaatggct tctgtctatc aacggccgat gctgatttgg
    13381 gataatattc cggtaaatga ttatttagag gataaagaac tattgttcat gagtccatat
    13441 gagaatcgaa caccgaatct ttctaaggag agataccagg ttacaggagt agtttcgaat
    13501 ccaatggctc aattagaagc ttcaaagttt acgatcaata gtatggctaa ttacttatgg
    13561 aactgtgagc gttttgatcc tttggaaact tggacgtcag tcgttgaaaa agtagttgga
    13621 agtaaactac aaccagctta tcttacctta accaatgctt ttccaaatca ttacacaagc
    13681 agtctgcttt cagatgaaga attactgcta gccaaagacc cagaatgggt cacaaaagaa
    13741 atggctgctt tagtccaagc agtaaaatgg atccagcaag aacaacatac atctagattg
    13801 agaacagaat tggagccttg gttacaagca atcacagaaa gttggacttt ctggcaagaa
    13861 tggcaattaa aaaaagatcc aaaagaagca gaagaatggt tggctaagaa aaaaacacac
    13921 cgcataggac gtgatttagt aactgcccat ttagagcaaa ttatcaaaag ttagatatct
    13981 taaaaaataa aaagcaagaa aaaggagaac aaaatggtca agagattaat tagtgcaaac
    14041 tacagtgatg tcaagaaaat gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa
    14101 ggacgggtga ttgtttgtga aacggttgct aatactcttc cacaatctgg agaaattacg
    14161 aatgcagaag ttgcgtcagc atttggtgca gatttgattc ttttaaatgg tttcgattgt
    14221 tatcgtcctg cagtttttgg actaccaaat gtgacgattg agaaggtttt tgatctacag
    14281 caaacgattg aaaacccgat tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt
    14341 aatttagaac ccattgcccc taaaacaaat atgatgagtg agaaagtaga aatcagccaa
    14401 ggaagagcaa gctctgttga aacgatacaa aaagcagaag aactaggagt cgattttatt
    14461 tgctttaccg gtaatccagg cactggagta accaatttag aaattactaa atccgtaaaa
    14521 atggcaaaaa agtatttttc gggattgatt attgctggga aaatgcatag cgccggctca
    14581 gaagagccag ttgtgaataa agaggcgatt atttcttatg cggaagcagg cgcagatatt
    14641 ttactagttc cttcagtagg gtctatccca ggctttttag agcaagacct aattgaagcg
    14701 gttcggttgg caaaaaaata tgatttgtta acgatgtctg caatcggtac tagtcaggaa
    14761 agtgcccgac cagaaacatt gcggcaatta gccattatga ataaaagttg tggtgttgat
    14821 ttacaacata ttggagatgc tggatacggg ggattggcac cagcagaaaa tattttcgaa
    14881 acctcggttg caattagagg aatgcgacat accatcaact gcgttagccg ctcgatcaat
    14941 cgctaacaaa attaaataaa aaatggttaa attgattatt taagtgggaa catacttgag
    15001 atatcagcta acttctgtca ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa
    15061 aaatatccga acaagagact aggatagcag aaaaactatc gttttgcaac gaggaccaac
    15121 tggaccgtag gagcaattct cttattgttc ggatatttcg cttgttcaag gacttatgtc
    15181 tgtagtgccc ttttttggta ggaaaaatgg tagggaacca tatcattttt aatgaaaatc
    15241 aagcatttca aaagt
//
LOCUS       DARBDN010000064        15230 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000064 DARBDN010000000
VERSION     DARBDN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.064"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            278..787
                     /locus_tag="SCH06_001930"
     CDS             278..787
                     /locus_tag="SCH06_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1078484.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="SCH06_001931"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="SCH06_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1078485.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="SCH06_001932"
     CDS             2322..3302
                     /locus_tag="SCH06_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1078486.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="SCH06_001933"
     CDS             3424..4842
                     /locus_tag="SCH06_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HEG1078487.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="SCH06_001934"
     CDS             4913..6382
                     /locus_tag="SCH06_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1078488.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="SCH06_001935"
     CDS             6392..6859
                     /locus_tag="SCH06_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1078489.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="SCH06_001936"
     CDS             6895..7767
                     /locus_tag="SCH06_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1078490.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="SCH06_001937"
     CDS             7848..10382
                     /locus_tag="SCH06_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1078491.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="SCH06_001938"
     CDS             10538..11311
                     /locus_tag="SCH06_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078492.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="SCH06_001939"
     CDS             11304..12095
                     /locus_tag="SCH06_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1078493.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="SCH06_001940"
     CDS             12105..12596
                     /locus_tag="SCH06_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078494.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="SCH06_001941"
     CDS             12614..13024
                     /locus_tag="SCH06_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1078495.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="SCH06_001942"
     CDS             13028..14428
                     /locus_tag="SCH06_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HEG1078496.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="SCH06_001943"
     CDS             14451..14825
                     /locus_tag="SCH06_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1078497.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2135 c         3046 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DARBDN010000065        13917 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000065 DARBDN010000000
VERSION     DARBDN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.065"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            131..505
                     /locus_tag="SCH06_001944"
     CDS             131..505
                     /locus_tag="SCH06_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEG1078498.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="SCH06_001945"
     CDS             complement(619..1248)
                     /locus_tag="SCH06_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEG1078499.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="SCH06_001946"
     tRNA            complement(1382..1454)
                     /locus_tag="SCH06_001946"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="SCH06_001947"
     tRNA            1668..1741
                     /locus_tag="SCH06_001947"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="SCH06_001948"
     CDS             complement(1879..2043)
                     /locus_tag="SCH06_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078500.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="SCH06_001949"
     CDS             2338..3666
                     /locus_tag="SCH06_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HEG1078501.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="SCH06_001950"
     CDS             3868..4701
                     /locus_tag="SCH06_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HEG1078502.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="SCH06_001951"
     CDS             4717..5454
                     /locus_tag="SCH06_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEG1078503.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="SCH06_001952"
     CDS             complement(5609..6577)
                     /locus_tag="SCH06_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEG1078504.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="SCH06_001953"
     CDS             6809..7642
                     /locus_tag="SCH06_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HEG1078505.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="SCH06_001954"
     CDS             7676..8515
                     /locus_tag="SCH06_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078506.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="SCH06_001955"
     CDS             8541..9101
                     /locus_tag="SCH06_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEG1078507.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="SCH06_001956"
     CDS             9300..11021
                     /locus_tag="SCH06_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEG1078508.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="SCH06_001957"
     CDS             11186..12328
                     /locus_tag="SCH06_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEG1078509.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="SCH06_001958"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="SCH06_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEG1078510.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DARBDN010000066        13810 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000066 DARBDN010000000
VERSION     DARBDN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.066"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(221..1423)
                     /locus_tag="SCH06_001959"
     CDS             complement(221..1423)
                     /locus_tag="SCH06_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1078511.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1426..1620)
                     /locus_tag="SCH06_001960"
     CDS             complement(1426..1620)
                     /locus_tag="SCH06_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEG1078512.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1667..2515)
                     /locus_tag="SCH06_001961"
     CDS             complement(1667..2515)
                     /locus_tag="SCH06_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEG1078513.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2720..3070)
                     /locus_tag="SCH06_001962"
     CDS             complement(2720..3070)
                     /locus_tag="SCH06_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078514.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3665..4111
                     /locus_tag="SCH06_001963"
     CDS             3665..4111
                     /locus_tag="SCH06_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEG1078515.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4735..5727
                     /locus_tag="SCH06_001964"
     CDS             4735..5727
                     /locus_tag="SCH06_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1078516.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5743..6627
                     /locus_tag="SCH06_001965"
     CDS             5743..6627
                     /locus_tag="SCH06_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1078517.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6676..8283
                     /locus_tag="SCH06_001966"
     CDS             6676..8283
                     /locus_tag="SCH06_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1078518.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8284..9768
                     /locus_tag="SCH06_001967"
     CDS             8284..9768
                     /locus_tag="SCH06_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEG1078519.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9945..10937
                     /locus_tag="SCH06_001968"
     CDS             9945..10937
                     /locus_tag="SCH06_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1078520.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10989..11858
                     /locus_tag="SCH06_001969"
     CDS             10989..11858
                     /locus_tag="SCH06_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1078521.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12278..13771)
                     /gene="guaA"
                     /locus_tag="SCH06_001970"
     CDS             complement(12278..13771)
                     /gene="guaA"
                     /locus_tag="SCH06_001970"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEG1078522.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4231 a         2337 c         2851 g         4391 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttacgtt gaaaaacgtt gatttatcgg cattccccat ccatattata
      121 tttacgtctt attcccactc aatatgagta gcctcgtaaa gaagctatta tatcagtgct
      181 ttttcagcct attcctcatt ttggtaggga aatggtaggg ttagattttt actgcttgat
      241 ttccattaaa gtttgcaact ttagattttg ttgcacaggt aaatttaatg tttcctgtca
      301 tttgttctgc aattccttca tcattacggc tccatagatg agcgtagtgc tttaaagtga
      361 tttcagggct agaatggcct aaccgttgcg acacgaccag aatgtctgcg ttaaactcat
      421 tgattaggta gctaacatga gaatgacgta atccttttcc ttgtattagg ggtaccttag
      481 ctagtttggc ataacgctga ataattcgtt gaacagttga acgatagagt gggaggtcag
      541 tgtagctaag aataaattgt tctacaccat gatttttttg aataactttc cactttttta
      601 gcacttcaat tgtatcatcg tccagagaaa tgatccgcaa gccgctttca gtttttgtgt
      661 aaggtttccg aataaaatct ttttgatttg tcatttccaa ggtgtgatga accctcaact
      721 ttttacgttt gaagtccacg tcattccaat taagtgctaa tccttcgctt acacgaacac
      781 cagtcatgta atatagccag atcattaaaa aacacatatg ttcgtagaaa tcatctttat
      841 aaatttttgc caaaacttct tcaaattctt cttttgtcca gtaaggaacg attgattttc
      901 cttttggaat tgcttttgtt cttttggaaa tattctcatt cagaaattgc agggtgaccg
      961 catagtctaa tgatttacga aacataccgt acataagtga actgtatgct tgtgagtatc
     1021 cgctatcgtt caataaccaa attcgataat tttcacaatc tcgcacattg atttcacgaa
     1081 gcttcttatc accgaaaaat tcagtaatct gaatcaatcc acactcacga gaactccaag
     1141 tacttttttg tacgctagct ttgtagtgtg gaacgtaaga ctgctccata aattctttgt
     1201 aagttaaatc ataattcgca aatccattta caaccatgta ttcatttttt atacgcatga
     1261 cttctttgtg tgcttcacga gctgatgaga atcgttttcc tagagaatct tttgttcctt
     1321 tcttctggat cctctttcca gtcacttgat ctgttcctaa ctcaactaga taagaaaagc
     1381 gaccattttt atcttgatac acacaagggt attttgtttt catagttatt cctcctgtga
     1441 aagaggaaca cctataattt cttcaattac ttgtcggggt actaccccaa ctcttttatt
     1501 attataatat ggatatccct gatttaccat tcttgttttt gcttgtcgga ttattgtggt
     1561 agcttgatgt gttttaaatc ctagagcctc taaatctttt cgacaaattg tatttttcat
     1621 tgtataaact cactttcaaa gaaaacacta tcattgggta atagtgttat ttctttattt
     1681 ttgtataatg aacggtactt tcttgaaaat ccatcacttg ttcaggactt cccaactcat
     1741 ttaaagctaa agcattgtaa aaaaatggac gtctaactat atattcgctt gtatatagta
     1801 tatcttgatt cgtggaatca tagggtttct ttaccatctt tttggtgaca gttggtagtt
     1861 tgagattccg ggacttgaaa aaagcttttt tcttatgctc tttcaattcc agctctttat
     1921 cgaaatattt gctgatatag cgcccgcgat tttcgatact gtctacatcg atcttgttga
     1981 tcttaacgaa accctgaccc caaatcgtag ttaaccggtt aaatgagata aaggggaaat
     2041 caaacaagat aatatggtag tggattgcac cgcgttgctg cttttcccac gtggcgagat
     2101 actttaaatt tgctttttta gttttataga ggtcataatt cagtcgtttg ataaattttt
     2161 taaattcatt atttgcatac tcaatgtctt gaatgttttc tttgaaagtg agagttaaaa
     2221 atttcgtttg attgtcaaaa ttcgtgtcta caaggcgggc aatctcaaat cgcatacttt
     2281 gataatgttt ctgtttgcgt tttaaactgt catattgtcc ttgagcggat aattcatcat
     2341 agttttttct tttttcaaga gtaatatcat tttcataaat ccaagctaat ttttgttttc
     2401 gttccagatt tacttcgttt tcgatcgttt tacgtttggg agtaatgatt gcttcataat
     2461 cataaatttc aatatacgtg ggagtttcaa tgattttctg attataagct tgcaaaaatc
     2521 atcactcctt gttgcgtatt cgattgtcaa agaaccagtc attttctcct gatgttgatc
     2581 tataaatcaa gttaaggggg aaggcctgcg tagcagccct tctagcctat ggggtgttgg
     2641 gcggtcttaa cggacagaaa cggctctgtg ggcgctgccc cgccgtttcg tcctaaccac
     2701 ccaacactcc atagtatagt tagttttgtg tagtggtacc ttgttttctg ggaatcaaag
     2761 ttgccgtatc agcggttgcc gataacccat aactgacaaa ttgtccattc gagcgtcccc
     2821 aaggtacaat caccaaattg gtaaatgtaa ttatggctaa accttgttgg gtaagttctt
     2881 ccggcgtgat cacaggatgt tcagatttga ctttgacact gattttttcg tagcgaagtt
     2941 ttggtaggat acattcgtag ctccaaccta gaatttcgcc ctccttttgc cagcgagtga
     3001 cattgacgac ttggtattct ttttcgagtg tttcttttgg taaactgaga tcggtaattt
     3061 ttattggcat cacaattctc cttttttata cgaaagttta tacgatttga ttaaaaaata
     3121 tagatggcca tctacgactt gtattatata cgagaactta tacgtagtca agagattttc
     3181 taaaaaaata tatacgattt tttatacgag tgttataatg aaaaaaatga taaggaggaa
     3241 tttgaatatg tttggtttag tacaacctaa taaagtgaag gtgggccaac gaatcaaaga
     3301 aataaaagac ggaatgtctc tctcttttac agaattaggg aatcgattag gtttaaaaaa
     3361 gccgacgatc agttcctacg ttcaaggcta tgcgttggct cctaagagtg tgatcaacca
     3421 attatctagt atcagcggaa aacctgtcgg ctggttttat tttgggcatg tggaagaata
     3481 tatccgagag tatttgtttc tcattggtca gaaaaaaata gtggacgatt atcctgaaat
     3541 cattgagaaa ataaagcaag aattttatac gggcgagttc aaaaatcctg cttgggagaa
     3601 tgagctaggc tatcctttgg aggaatttat ccaagaatgt tttgtagaat attcgagtga
     3661 aatcatgaag gactatgtcg tacagattac gaaagaggta cttgaagaat ccaaaacgct
     3721 aaacaaacta tcatcaaaag caaaagaaga agctgtcacg attctttcat ctgggatcat
     3781 tgactatatc gagatgagtg gtgagatcaa gtatggagag aaagatcgca ttgcgaaaat
     3841 ggtgaaagaa tcaataaaaa cctttgatgt gaaacaagac ctgacattta atgattccta
     3901 tttgattgga aagttgatca atattcttgg tacagatgaa gatacggagc tgtttctttc
     3961 ttctttatca atgatattta ctgataagca tttttccact cgatttggtg gggaagaatt
     4021 agtcgaaata tttcaatcga tgcgaccagc gttaatcaaa ctctatcggg agaaaacacc
     4081 agatgaattt tatgattggt ttgagaagta aaataagaaa agtggcttag attacaagtt
     4141 ggtgaaaaaa tttttttcag cataacatca gtaatctata aaggggttgt tgattatact
     4201 gtagaagtta agtactcaag agattttttg tacgtaaaca aagcaaaaaa gggtgcagtt
     4261 tcactagaaa atgtactctt ttttgtgatt tttcttagtt atagagtttt tttgaaactt
     4321 taaaaatgag aaaacatatt gattttaaag agtgtagaca tagcttcttt tgctaaatag
     4381 attaaactta ctggtgagtg gtcttgaaca tacttttaaa tcacatttta ctgagtttta
     4441 ttggatttta taattcattg gaaacctcgt acttaatctg tttttatcta tcgactagaa
     4501 tctgtatata ttccagctat caatgaggcc gcagaaaagg gtgcttaaaa ataatctgtt
     4561 gtttaaaata ttattatcag aatacttaga tacaaaattc tggcacaaag taaaaaaaat
     4621 attgacttaa aaaaatggat atggtaatct ataaacgaaa atagtggtaa cgtttccaaa
     4681 atgcatcttc gttaaatttt tattttttta aacgaaaatg gaaacgtttc taaaatgtat
     4741 tgggaggaga ttgaattgga aaagacattg ggaccaggtg gtgagataag ggcggtacaa
     4801 cgggataaaa aaaatatttc gaagtgggaa aaattaaaga aacagttgcg gcgtgataag
     4861 tggatgtact tgttgctctt accaggtatc atcatgacgt ttatctttaa gtatgtgcca
     4921 atgtacggtg ctgtgattgc atttaaagac tataatccta tgctaggaat tttggaaagt
     4981 ccttgggtag gactagatca ctttagggaa tttatcagtt caccaaattt tacgcttttg
     5041 ctgagcaaca cattaaaaat tagtatttat ggtttattgt taggtttttt tccaccaatt
     5101 attttagcac tgagcttgaa tcaaattatc aataaaaaaa taaaacagaa aatccagttg
     5161 attctatatg cgccgaattt tatctcagta gttattattg tggggatgct gtttttgttc
     5221 ctatccgcaa atggacctat taatgggtta gtagaaaagg ttacggggca accaattatg
     5281 ttcatgtcta atccagctta tttcagaacg atttatattt tatcgggaat ttggcaagga
     5341 atcggctggt catccattct ttacaccgca acgctggcgg gagtcagtac cgatttatat
     5401 gaggcagcaa atatcgatgg ggcaaatatt ttacaaaaga tttggcatat cgatttgcct
     5461 gcattgaggc ctgtgatggt gatcagcttc atcttggccg ccggcggtat tatgaatgta
     5521 ggatatgaaa aagcctactt gatgcaaact tcaatgaaca tccctgcctc agaaatcatt
     5581 tccacttatg tatacaaagt cggcttgcaa tcaggtgatt atgcctactc tgctgctgtt
     5641 ggtctgttca atatgattat taatgtcgtt ttattactga ttgtcaacaa tataaccaag
     5701 cggctaaacg atggtcaagg cttgtaatga aaggagaaaa ttatgaatag tgctttatca
     5761 aaaatcgacc gtcaaatctt atggttgaat cgagtgattg taactttttt agtcgtcatc
     5821 accattgttc cgctgattta tgtactggta gcttctttta tggacccagc tactttgatc
     5881 aataaaggta taagcttcaa tccgaaagat tggacaatac agggatatca acgggtattt
     5941 gcagatgatt ccattttacg cggttttgta aattcgttgt tttactcttt tagcttcagc
     6001 ttattgactg tatttattac gatgatcact gcgtatcctt tgtctcgacc taacttggcg
     6061 gggaaaaaga ttattatgac tttttttgtc attacaatgt tcgtgggtgg tggcttgata
     6121 cctacctatt tattggtaaa gaacttgggc atgttagata gtgtatgggc gattatcgta
     6181 ccaggtgcta taaatgtgtg gaatattatc ttagcccgta cctattttag tgctttgcca
     6241 aaagaacttt ctgaagctgc tactatcgat ggcgccaatg acttgcaaat actgttcaaa
     6301 gtcatgcttc cattagcgaa accaattatg ttcgtattgt ttttatatgc ctttgttggg
     6361 caatggaact catactttga tgccatgatt tacatcaaag atcccgactt acagccgttg
     6421 caactcgtat taagaaatat tttgatccaa aaccaacctt cacaagacat ggtgggagcc
     6481 aatactgcca tggcagaaat gaaacaaatt gctgagttga tcaaatacgc aacgatcgtc
     6541 atttctagtc tgccattaat cataatgtat cctttcttcc aaaaatattt tgataaaggt
     6601 gttttagttg gttctgttaa agggtaagta ttgttcacta tttgtatgaa taaaaattat
     6661 aaaggagatt ttaagatgaa agcaaaatgg atgctgccaa tcgtttttac ttccgtacta
     6721 attttggggg cttgtggagg ctcaaaagaa aagagtaaat caagccctga ttatgaacta
     6781 gaaaatgtct cttttccatt gaaagaaaaa gtatctttaa aaatgatgtc tcaaagtgcc
     6841 cctttggctc ccaatgatcc taatgacaaa ttgattttcc aacgattaga agaagagacc
     6901 aatctccata ttgattggac aaactacagt agtgattttg ccgaaaaaag aaatttggat
     6961 atcgctagtg gtgatttacc agatgccatc ttcaacgccg ctgcaggtga ctatgattta
     7021 ttaaactggg cggaaagtgg cgttattgta ccgattgaag atttgatcga agattatatg
     7081 ccaaatctga agaaaatttt tgatgaaaac cccgaatacc gacaaatgtc tactgcacct
     7141 gatggtcaca tttactctat gccttggatt gaagaattag gcgaaggaaa agagtcgatt
     7201 catacagtaa atgggatggc ttggatcaac aaggagtggt tggataattt gggtcttgaa
     7261 atgccgcaaa ccactgatca gttgatgact gtgttggagg ctttcaagac gcaagatcca
     7321 aatggtaatg gtgaagcaga tgaaattcct tttagcttta ttaacaatgg aggaaacgaa
     7381 gacttaaaat ttttaatggg ggcattcggt ctaggtgata atgatgacca cttagtcgtt
     7441 gataacgatg gtcaggtaca atttactgct aacaaagaag ggtataaaga agccatcaaa
     7501 tatttcaatg aaatgaataa taaaggtctt attgataaag aggctttcga acaagattgg
     7561 aatacgtatg ttgccaaagg gaaagaacat aagtatggcg tgtactttac ttgggataaa
     7621 gcaaatatca cgggtgcaga tgatagttat gacgtcttgc cagtcttagc gggaccagat
     7681 ggaacgaaac atgttactcg tacgaatggc atgggtttct caagagatcg tttcgtaatt
     7741 actagtgcga ataaaaactt ggaacttaca gctaggtgga tagataaaat gtatgaaccg
     7801 ttacagtctg tccaaaataa ctggggaacc tacggtgatg aagcacaggc gaatattttt
     7861 gaattaaagg atggtatgtt aaaacatttg cctttagagg ggacagcacc gggggaacta
     7921 agacaaaaaa ccgaagctgg aggaccatta gcagttcttg attcttatta cggcacagtc
     7981 actactatgc cagatgatgc gaagtggcgt ttagatttga tgcatgacac gtatttgcca
     8041 tatattacag aagacaatat ctatccacgt gtctttttag aaaaagaaga aacagatcga
     8101 ttagcaaaaa tcgaaacgga tatgtgggat tacatctatc gcaaaagagc agagtggatc
     8161 accggcggta aaatcgatga agaatgggaa gaataccttg ctgaattgga acgtgtaggt
     8221 ttggaagaat ggattcaaat aaaacaaact ggctatgata attttttgaa gggagcacaa
     8281 taagtgttag tagaagaaac ggcgattttg gataaagcaa atcgatttat tgaaatgatg
     8341 cgaggaaaag ttaaccctca gtatcgacaa aactatcatt tttccgcacc catcgggtgg
     8401 ataaatgacc ccaatgggtt tatatattac aaagggcatt accatctctt ctatcaatac
     8461 tatccttacg atagtcgatg ggggcccatg cattgggggc atgcgcgcag tagtgatttg
     8521 gtccattggg aagatctacc agtagcgtta gccccagatc aaccttatga cagcggcggg
     8581 tgtttctcag gaagtgcaat tgaaagagac ggaaaactat atttatttta tacaggctgt
     8641 caagaaattg atggtattag ccatcagcat caatgtttgg cggtctctga agatggtatt
     8701 cattttagca aatacagtgg taatcctgtg gtagcagaaa aacagctagg tgaaaatggg
     8761 ctaatacaag aatttcgtga tcctaaagta attgttcaca acgatggtta ctatatggta
     8821 gtagctacta aatctacaca gtctactggt agaatagtga tgtttcaatc gtcagatttg
     8881 tatacttggc acttttactc tgtgctgcta gaagggactt cagagcaagg aataatgtgg
     8941 gaatgtcctg atttattcca tttagacgga cgagatgtct taatcatgtc tccgatacaa
     9001 atcaagaaga acggactgga atatcataat atcagttcta ccatggcttg tattggtgag
     9061 gtaaactggg aaacaggtca gatgatagtt gataatttcc atgaaatgga ttttggaatg
     9121 gatttttatg caccacaaac aacaagagat cctaatggtg gacgggtgat gattgcttgg
     9181 atgcagatgt gggatcgtac attgcctaca catgagttag gccatctttg ggcaggctct
     9241 atgagtttgc cccgagagtt aagagtgaaa aaaaatcgat tggtacaaaa acccatctca
     9301 actgtatata gtcatttagt ttatcaacaa ggcagtgaaa atattgcagt gactgacaca
     9361 tcagtcgtat ttcgaaacgc gctgtctgat tcttcatatt tacatctagt cgcagatttg
     9421 gagaaagctg aagtttttac aattgaatta ctgcggtcta agacggattg tctcaaacta
     9481 gcctatgaca ctgctacaca ggtttttgaa ttggatcgtc agaaactagg aagagagctt
     9541 acaggggcgg aagaagaccc tctgaatgta cgaaaagttg aagtaccttt gattgataat
     9601 cagctcgttc ttgagatttt tagagatacc tcatcaattg aagtctttat taatgggtta
     9661 gaagttatga cggctacttt ctatgagctg gaaaaagctc gagatatctt gtttcattcg
     9721 atcggagaaa gtcgtattca agcttttgaa acagcgagtg tgaaataaat gtttgattgc
     9781 ttaggcgatg aatcaattat ttaataggtt ttgaaggata atgtttttag aaaagaacag
     9841 atagctagat ttcccatgga tttgctatta gtattttgaa aaaattagta atttatgaca
     9901 aaattcatta tactaaactt gtgcagaaat gtgagggatc aactatgaaa gcaacaatga
     9961 aagatgtcgc aaaattagca ggtgttggag taggaactgt ttcccgggta ttgaataacg
    10021 gttctgttaa agcttctact agagaaaaag ttgaagcagc aatgacagag ttaaactatc
    10081 aaccagattt ttatgcccgg gggttaaaga tgaagcatac gaacacggtt gctttgattc
    10141 tacccacggt atggcatcca ttttttggcg aatttgccta ccatgtagaa acagcattag
    10201 aaagacaaaa ctacaagctt tatttgtgta actccagtgg taatagtgaa aaagaacaag
    10261 aatatatcca gatggtcagc caaaataaag tagacggcat cattggaatt acttattcag
    10321 atatcgatga atacatttcg agtaatctgc cttttgttag tattgaccgt tatttcactg
    10381 aagaggtgat ttatgtgacc gctgacaatg cggccggtgg acgtttggct gcaaatgaac
    10441 tttatcgccg aggatgtcag aatgtagcat atatcggtgg gtaccaagaa acaccgaatg
    10501 aaacgaagag tcgtcgaaaa tattttgaaa tcgagtgccg tcaactgggg atttcctata
    10561 aagcgttaga tatgttagaa cctttagacc atctctcaga acgtgtaaca aattttttgt
    10621 tagagaatcc cgatatcgat gggattttta cgatcaacga tccaatggca ttagctgtca
    10681 ttgatatgct tgaaaaaata gggaaaaacg taccagagga tgtccaagtt atcggatttg
    10741 atggtcaaaa gatgacagaa ggagatcctt atctagtctc aacgattgcc caacctacaa
    10801 agcaaatggc ggaagtggca gtggcaaaat taattgctgt cattaatgga gagacagtag
    10861 aaaaacgtac cgtattgccg attgaatttg gcgaaggtga cacaacgaaa cctttagtga
    10921 gaaacgattt tgcttagtgc aaatacgttt ctttttttga aaatgagtga atgaaaggtg
    10981 tagataaaat gttatatggt ggaatagaag ccggtggaac aaagtttgtc tgtgggattg
    11041 gtaatgaaca attacaagtg atagaacgga aaagttttcc taccacaaca ccagaagaaa
    11101 cgatggagca agtgtttgat ttctttgata agtacaaagg aaatatcgca tcaattggtg
    11161 taggagcatt tgggcctatt gatattcaaa tcgaatcaag aacttacgga tatatcacca
    11221 acacaccgaa gttagcttgg caaaattatc attttgtagg agctttggaa aacgccttgt
    11281 cggttcccat ctattggact accgatgtaa atgctgcttg ttatggagaa tatatggcag
    11341 ggtatggaaa aggtaaaaat agtgttctgt attacaccgt tggtacaggt gttggtggtg
    11401 gtgctgtagt ggatgggaaa atagtcgcag gttttagtca tcctgaaatg ggacatatgc
    11461 tcttacaacg tcataatgaa gatcaatttg aaggaatctg tccttttcat catgattgtt
    11521 tggaagggtt agcatcagga cctgcgattg aaaaacgctt tggaagaaaa gcccagacta
    11581 tctcatttga tcatccttat tggacgattg aggcagatta tcttgctcag tgtgtgtata
    11641 acacaacgtt actatatgca ccggaagtaa taattttagg cgggggtgta atgaaacagc
    11701 cgcaactact cgagttgatt cgccaatcgt ttaaagaaaa aatgggttcc tacgtggata
    11761 cgcctactct cgaagaatat ctactaactc caaggcttgc tgacaatgcg ggcttgattg
    11821 gctgcctagc tttagcaata aagaaactca atcattagaa tagtatttat tagaactatt
    11881 cataacatac cggaagttta aaagggtatt ctgaaactta aatagtctca attcattctt
    11941 ctttcttgag aatctgagta gagactttta ttctgtttca aattaatata attacgaaat
    12001 gatattgagt acaagaaagt tctttttacc agatctttta aatcgaaaaa tctgatatat
    12061 atatttatag tactaaaaat ctgattagat aaaaagctaa ttcaatagga aaataaaggt
    12121 agtgaataaa agcaaagccc ttgttagtag ttaatctaac aagggctttg gtagggaaaa
    12181 tggtaggaaa ccatcttatt ttttacgaaa atcaggaact ttagtaattg aataatgttg
    12241 atttataggt attcctcatc catattatgt tggctcttta ttcccactcc actgttgcag
    12301 gtggtttgct ggtaatatca tacacgatac ggttaacgtg tgcgacttca tttacgatac
    12361 ggacactgat tttttgcaag acttcccaag ggatacgggc aaagtcagcg gtcatgccgt
    12421 caatagaagt gacagcacgg atacctacag tgtagtcata cgtacggcca tctcccataa
    12481 ccccaacaga gcgaatgcct ggtaggacgg tgaagtattg ccagatgtcg cgatctaaac
    12541 cggcattggc gatttcttcg cgcaagatag cgtctgattc acggacgatt tctaattttt
    12601 cttctgtcaa ttcaccaagg acacgaatac ctaagcctgg tccagggaat ggttggcgcc
    12661 aaacgatgct gtcaggcatg cctaattggg tacctaattc acgtacttcg tctttgaaca
    12721 atgtgttcaa tggctcgatc agcttgaatt gcatgtcttc aggtaatcca cctacattgt
    12781 gatgtgattt gatggtttgg gcagtttcag ttcctgattc gatcacatcg gtataaaggg
    12841 ttccttgtgc aaggaaagaa acgccttctt caccggcaag tttggttgct tcatcatcga
    12901 agacatatac aaattcattt ccaatgattt tacgtttttc ttctggatca gacacgccag
    12961 caagttttga taagaaacgt tctttggcat cgacttttat aatgttcaag ccaaattttc
    13021 cgccaagact ttccataact tgttctgctt cacctttacg caacaatacg tgatcaacga
    13081 agatacatgt taattgatcg ccgatcgctt tttgtaaaag aacaccaaca acagaggaat
    13141 ctactccgcc tgaaaggcct aataaaactt ttttgtcacc gacttgttca cgaatttttg
    13201 cgatctccat gtcgatgaag ttatccattg tccagtcacc agtacattgg cagacatcta
    13261 gtgtaaaatg gcgcaacaag tcatttccat attcggaatg gcgaacttct gcatggaatt
    13321 ggattccgta cattttgcgt tctgcatttt ggatcgatgc gatggggcaa tctttgctgg
    13381 tagcaacgac atcgaaatca gtcggtgctt gggtaactag gtcaccatga ctcatccaaa
    13441 cggtttgttt ttcaggagtg ttttggaaaa gggccgcttc tgcagaagtg atttccaatt
    13501 ctgcttttcc gtattcacgg tttttggctg gtttaacttt tccgcctaat ttataagtaa
    13561 tcaactgcat accgtaacag attcctaaaa ctgggatccc caaatcaaaa atcttttcat
    13621 caataccaaa ggccttctca tcataaacac tgtttggtcc gccagaaagg atgattcctt
    13681 tagggttcat tgcctttact tcttctgcgg taatgcggtg gctcatcaac tctgagaaaa
    13741 caccgaactc acgaatacgg cgagtgatca gttggttata ctgactaccg taatcaagta
    13801 cgataatttt
//
LOCUS       DARBDN010000067        13781 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000067 DARBDN010000000
VERSION     DARBDN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.067"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            156..494
                     /locus_tag="SCH06_001971"
     CDS             156..494
                     /locus_tag="SCH06_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078523.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(699..1274)
                     /locus_tag="SCH06_001972"
     CDS             complement(699..1274)
                     /locus_tag="SCH06_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEG1078524.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(2006..2587)
                     /locus_tag="SCH06_001973"
     CDS             complement(2006..2587)
                     /locus_tag="SCH06_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1078525.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(2770..3396)
                     /locus_tag="SCH06_001974"
     CDS             complement(2770..3396)
                     /locus_tag="SCH06_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEG1078526.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(3418..4749)
                     /locus_tag="SCH06_001975"
     CDS             complement(3418..4749)
                     /locus_tag="SCH06_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEG1078527.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(4904..5305)
                     /locus_tag="SCH06_001976"
     CDS             complement(4904..5305)
                     /locus_tag="SCH06_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEG1078528.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5391..5597)
                     /locus_tag="SCH06_001977"
     CDS             complement(5391..5597)
                     /locus_tag="SCH06_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078529.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(5692..7194)
                     /locus_tag="SCH06_001978"
     CDS             complement(5692..7194)
                     /locus_tag="SCH06_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HEG1078530.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7212..7667)
                     /gene="argR"
                     /locus_tag="SCH06_001979"
     CDS             complement(7212..7667)
                     /gene="argR"
                     /locus_tag="SCH06_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEG1078531.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(7765..8382)
                     /locus_tag="SCH06_001980"
     CDS             complement(7765..8382)
                     /locus_tag="SCH06_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HEG1078532.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKPFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQLVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            8603..9976
                     /locus_tag="SCH06_001981"
     CDS             8603..9976
                     /locus_tag="SCH06_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1078533.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10051..11163
                     /locus_tag="SCH06_001982"
     CDS             10051..11163
                     /locus_tag="SCH06_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEG1078534.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWSTEDYQKDISTYITKNPS"
     gene            complement(11235..12872)
                     /locus_tag="SCH06_001983"
     CDS             complement(11235..12872)
                     /locus_tag="SCH06_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HEG1078535.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13040..13648)
                     /locus_tag="SCH06_001984"
     CDS             complement(13040..13648)
                     /locus_tag="SCH06_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1078536.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         3734 a         2892 c         2462 g         4693 t
ORIGIN      
        1 aatttgacaa ttaagaaact aaaaaaataa tccaagaaac attgaaccta tggatccaaa
       61 agctacccaa atactatagc taaccccccg ctaccttcaa ttttgcagat aaaacgcttt
      121 gggagaaaat ttcaaagaca acaggccatc ctatcatgcc cgattataaa caaaaagctg
      181 gctattcctt ttgctctgac aaatttcaat tgggaaagtt cacgaaacta gcaggtgaag
      241 aagtttcaac tgttcggatc aaagaatgcc cgcttcaaat agaaacattg gttcaacgaa
      301 tttcaactag acaagacttt gctattgtag aacgtgagat cgtagctatt tttgtagaag
      361 aagggatttt acatgatcca actcatatca atgtggataa atggcaacct cttatctata
      421 aattcagaga atatacaact gccaaccagt cgttaacttt gaattttaga ttccaagaat
      481 tcaaagagtc ataatgataa acatcgttag gtataaataa aaaagactcg cagcacgagt
      541 aaaaaacaaa tagaagctat acattagaaa ggtcgactgt gaccctatag atgcagtata
      601 tgcagcttat gagcatttct tctgttctct ttgtttttgg gatctgtgct gaagtctttt
      661 tcgttttttg ccgctctttc tttgaaaaat cgattatgtt ataccttctc cattactaat
      721 tcaggcatct gctgagtaat gatttttcgc gcaaaagaaa tatctgttac ccaaggttcg
      781 atttgttctt cagtcaagac aagcggcatt cggtcatgga ttggtgcgac tgtgcggtta
      841 ggttcagtag tcattatgat tgattctgcc attttttcat cctgatggct acgataaaaa
      901 ccgccaatat acactatttt ttccttattt gaaaacataa atttgtcttt ttcttcattc
      961 cactcataaa agccactcat tgggaaaaca caacgatttt gcaaaaatgg ttgatgaaag
     1021 gtcttttttt cttctactgt ctctgcacgg gcattaatca tcaattgtcc ttttttaaat
     1081 ccggtaaatc cccacttcat gatttccgga gtgaggatgt tttcttcctc ttttcttaac
     1141 gtcacaacaa gatttgacgg aaaaacttct ccagctgcta attctgctgc ctgcttcggt
     1201 tgtttcgtct gggcttctcg ataataattc tgaaggagct ctgactctag atcaaaaaaa
     1261 taacgaccac acatcctaat ccctcccaat ctttttttct atcatacact gcaacaagaa
     1321 gttcgcacca acaaaacgct ttcaattttt gtagaactaa aaaagttgtg acaagtgaca
     1381 aactctccag tgaatggtat tctcctgcca actcctcggt cacaagtcac aatattcaac
     1441 aaacatgaga agctgctttt tgaaattgtt ccttgtgact cggagtgaaa cggcaggctt
     1501 acgacctctg ggtaaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatgc
     1561 aaaaatgtag aaagccattt tcacaaaatt tttcttaata ctcgaaacta agcgactttt
     1621 tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
     1681 aacgaaaaat atgagcagct atttttattt ggctgttctt attacttgat gcagggcagc
     1741 tttttcacaa cctctccact aaacggtgtt caatcagcta accttcggta ttagctcaaa
     1801 aaacggcaaa atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaagcg
     1861 ctgatttcac aacctctaat acacggtgtt ccagaagtag cttcttcgaa aaataagccg
     1921 aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc ttgaagctga
     1981 ccacttctgt cacaacctct aattattaaa gaaccttttg cgaagttaac aatctttctt
     2041 tgatcaattg aaaattctgc ctaagtagtg atagatcctg tgtgactttc aacaataaga
     2101 tacttccctg gatttcagca atcaacgctt tggcttgacg gtctgcttct tcatcggaca
     2161 gtttttcttc agaaagtgcc aggatatttt gtttcgtata cttgacccat tgattgacta
     2221 attctagtag caacagacgg tattcttcat ccactgtact caactcaata atcaaattac
     2281 ctacaggaca gccatgataa gtgatctgtg tctcatgatc agcgaaaatc cagtccaaca
     2341 tttcttctaa tgcttcttct ggctgttttc cagcatttaa gatgtcttcg aacaattctg
     2401 tctgccatac gtccatatgc gcatggatca ccgctagaca aacttctttt tttgaagaaa
     2461 agtaataata aaattgacct tttcctgtat cagaagctgc tagaatatct cggattgacg
     2521 tttcatgata gcctttttta taaataagat ctttggtcgc ttccaagatc ttttcctttg
     2581 ttttcaatga tattctcctt tttcatttct catagtccta tattatacag taaattcatc
     2641 attttttctt cttaatcgtt taaaaaagac tgtgccaaat tatctgacac agccctcact
     2701 ataaaactgt tctcatatag ctagatgttc attgattcaa gaactgcgag gacaaaagca
     2761 attcctatct tatgatagtt gctctaatac ttcctctgtt gtcatcactt gatctgcaat
     2821 aaagccaaag ttcgtcaacg ctgcatccat tgcttcttgg ccaggagcac caattgcatc
     2881 tgtcgctacc acaacattga atccactctc taccaattca cgcatatggg aatcgctaca
     2941 caagtttccg ttcattccac caagaattac tgtgtcgatt ccattttttc tcaattggag
     3001 cgccaaatca ttgctttctg gtccaaagat tttatgagga gagctgatga tcgtattttc
     3061 atccaaataa ggtttcaatt cttcgataaa atcggctcct gaaccttctt ccactgattc
     3121 atattgactt tttctagcaa acatctgctg ctcaagcatc atatgttctc ctgcaccgcc
     3181 aaattgccat ttatggtcat gtgggtaaaa ataatgagga gaaataaaga gtttgtatcc
     3241 tttttctttt gcttgtttta ccatttcaat catattttcg atcgtattgt atttttctaa
     3301 gatatctttt gtcaaaccaa agccaccgcc tgctggtttc aagaactcga cttgcgggtc
     3361 agtgagaact actgctgtat ttttattatt gaacatggtg gattctccat tcgttattta
     3421 ttttaataca tcatttagag cttcactcat tgtcggatga gaatagattt gatctctcaa
     3481 taacgtataa ggaagttttc cattcatagc tagcgaaatc aagttgatga cttcatgaga
     3541 atcttccgca tagatacttg cccctagaat caagtcagtt tcagggtcga ctaaaacttt
     3601 gaatacacct ttaggatctt ctaatacttg tgctttaggg acaccgcttg tcatatactt
     3661 gaataatttg taattgacgc cttgtgcttt ggcttgtttt tctgttaaac ctacattgga
     3721 taaagtcgga gtgataaata cactgtaagg cacagctttc cggttattcg ttgttcgttt
     3781 attctcgccc ttcaactgat ccataatgat tcgataatca tctagagaga tataagtgaa
     3841 ctgcaatccg cctttgacgt ctccaatcgc ccaaatgttg tctgcatctg tacgaaggta
     3901 ttcatccaca gcgattgctc cgcgatctgt tagtttaaca tctgtatttt ctaatccaag
     3961 tgatgctgta cttggttttc ttccagttgc agccaaaact tttgacgctt ggattgttac
     4021 ttcttggcca tcttctgtaa aggtgacggc agctgttgat tcttggtctg ctacttgatc
     4081 tacagataca cctagatgga attcgattcc cgcatttgtc atgtcttcta aaatcatttg
     4141 cgcgatatct tcatcttcac gtggaagaaa ttcagaatgg gcatcaagaa cgacaacttt
     4201 agatccgtat tcattgaaca ttgatgcaaa ttccaagcca atatatccag ccccgatgat
     4261 cactaatttt tccggtaatt gttcctgatc catcgcttgc gtagaatcaa tcaagtagcg
     4321 acttgtattc aatcctttga ttggtaaaat gattggttca gaaccagtat tgatgaaaat
     4381 ccgttcgcct tcaacaatca ctttttcacc attattcgtc acttcgattt gatggttaga
     4441 aagaaaacgt gctgtaccgt ccatcactgt cccagttgcc tcatcgctga tcatatgata
     4501 atttttggcg cgaagcatgc ccgtcaattt ttctttccga gcaacagcct ctgtaaagtc
     4561 gattcctctt tctccattga aaatcaatga tttagaagga atacagccga tgttgataca
     4621 tgttccgcca tacatacgtg ttgacttttc aacgactaaa accgattcac cttttgaagc
     4681 taacgccttc gctaaagtct taccgccctt tccaaaaccg atcacaatat tttgatattt
     4741 ttccatcatt tttccctcgc ttctttttta cctaccgatt ggtacaaaaa tatgataacc
     4801 gataattgtc tattctccaa atcatctgct ttatttgtca aaaaaaacca gacaaaaagc
     4861 ggtcctttca cgtttttagt ctggttcgat ttcctttatt cttctaaaca atcgttactt
     4921 ctacatcgat atttcctcta gttgctttgg agtaagggca gaattcatgc gcatcttctg
     4981 caattttttg ggcttcttct tcgctgatgc catcgatatg cacttctaat actacaccga
     5041 tctgatagcc gccatcatct aaattataaa gagagacacg tgcttttact gtggactctg
     5101 ctgtcattcc tgcttctttg atcatatgtt gtaccgcccc attgaaacaa gaagcataac
     5161 ctgctgcaaa taattgttct ggatttgttc cttctgcatg gattcctgga ggagtgattt
     5221 tcatatgcat cgagccattt ggtgcctcga cttctccatt gcgcccgcca tggttgatca
     5281 ttgctgtttc gtatgctttt ttcattgtac tgctcctttc gattgaccat ttgctacttg
     5341 gctataatta tagtgtatga caagtaaggc gctttctaca aaaattctgc ttattcgaat
     5401 accagaatgc cgtcttctac tatttttcca aaaaacaaaa aaatactact cgtgaacaac
     5461 agcgtcatat ttgttccaaa ataaatagca atcttttcta cataatcttt tatatgattg
     5521 attttaagat acatatatac cagaaagttg accccataaa ccaatactgt taaaaaaata
     5581 accatattcg ttaccatttt ttcctccttt tgctggtctc cctaccagca ctcgatttaa
     5641 ccataccact ttttttgccg tccaagcaac tagcctttca aaaagactgg tttattctgc
     5701 tgttaatgat tcaagatcag aaaaatgtcc gaataatttt gctaatttta ctaacgccaa
     5761 cttgttcttt ccgaattcat cattttctat ctgtaatact agtaacggct catgtaagct
     5821 taaacggatc aaaaaccagc cgtttccgta tggctcttct agatcatatc gaataccttc
     5881 ttcattttcc gggtcgaagt tcatcccttt ttcttcttcc aacagtcgct tcatttcttc
     5941 taatatcttg tttccttgtt cgcgtggttc atcgctgaac aattttaatc ggatttcttg
     6001 tacttctacg ggctgtttca actctttgat ttgttcatct aatgtgatac cttttctttt
     6061 taattctggc aaaagcatca ggatctttgc gatgacatat gcaccatcat ccagaaaata
     6121 gttttccttg aatgcagcgt gtccgcttgt ttcgatggct agctgtgtat ctttcccaag
     6181 acggttaagt tctaatgctt tattgattac atttcgatag ccggaaatat aacgaacttg
     6241 gatgcctcct ttttcttcaa tgaatctttg tagatgagaa gaagtagggg aattcgtcac
     6301 gattcttgtt cctggatgct cttttaatac gattgtactt aatactgcga tcaaattatt
     6361 tcgattgatc actgttccag aagcactgac aactgcagaa cgatccacat ctgtatcgaa
     6421 aatgatccca agatctgctt catttgctaa aacagcctgc ttgatacttt ccatcgcttc
     6481 tttattatca ggatttggga tatgattagg aaatcggcca tctggttcca aaaattggga
     6541 acctgttgaa tccgcaccta agctattcaa tactttttca gcaaagaatc caccagcacc
     6601 atttccggca tcaacaatga ttttccaacc atttagtggt ttgctttcta gtgttccaat
     6661 ccccttttta atttttgtga ctaaatcttg cgcataaggt gtcaaaaggt ctgctttttc
     6721 tacgcttcca gtttgttcgc tttttatttt ttgctgctgt gataggataa aagcaatatc
     6781 ttctttttct gctcctcctt ctgaggtaaa gaattttatt ccattataat aatagggaag
     6841 atggctagca gtcagcataa ccgcagcatc gcacgagaac tgttcaaatt gagtggacat
     6901 aaacatagca ggcgtagtag ctaattcgaa atcgatgaca tgtatccctt gttctttcag
     6961 actttggatc aacgcctctt tcagtgctgg tccgcttatc ctactgtcat gaccaatccc
     7021 aatcgtccat tttttatttg gatcggttga tttcttcttt ttctttatcc agtttgctag
     7081 tccccagccg atctttttta ccatgtctgt cgtcaagttt acttcatatc cttcaactgg
     7141 taatgcgatt cctcgaatat ccgatccatt ttgcagcgct ttcatatctt tcatataaaa
     7201 gtcctcctca tttattccct cattttttcc agcttttctg caaatcgctg tgcttcttct
     7261 tctgagcggc aaataataat gaatgtatct acaccggcca tcgttccgac aacttcaggg
     7321 taagccactt catctagcca attcgttacc acatcggcac catttcgttc agtcaatacg
     7381 ataaccatga actgaacaga ctggatacgc aaaacctcgc gtctaattgc tgtacgcaaa
     7441 cgttcttcat ttaaagaaac agatggctgg ttaaataatg tatagcgtac tattttgttt
     7501 tcattttgac tttttactaa cttcatttct cgaatgtctc gagaaatcgt tgcttgagtc
     7561 acatcggcgc ctgcttcatg cagccgcgca agcagctctt cctgtgtccc aataggttgt
     7621 tctgtaatga tctggcggat cagtgcttgt cgctgtttct ttttcatatt agacacctct
     7681 caatgttgat tatagcaaaa gataagtaat atttcttcat attttggtat tttttacttt
     7741 tattttttgt tttcattcag gttgctaacc tttttctatt ttaacacgca aaatcgtctt
     7801 cattttttca ggtgctgatt ttcttggatc gctgatgtaa atctctttgt gttctttaga
     7861 agctctttca tagccttctt ttgcgatgaa tgcttctaat ttctcaaacg ttgctggttc
     7921 ttcggcatag ggcccgacgt gtaagatttg ggcacaaaga ccttcttcca tctttttgaa
     7981 tactagttgt tctttcaagt cttccggaag tttgctagaa cgctgaatgg cttcttgtgc
     8041 tatcgcttct gtaacaaagt caggctgtcg gatcatcaat tgataagaaa aatgttcttt
     8101 tttcatcact ggttcatgca aatacttttc ttgcagtccc cattgtcctt ccagtggata
     8161 gacagtatac atctgataat caggaatcag ccaatttttt ttaggcgaca tgcgtattgc
     8221 atagctgact gcatatagac aggctactct tcgtttaaag tcttcctgat tcgggtcgcc
     8281 gatccctctg atgctaaaga atggtttttt aggaacctct agtatttgcg ggcttttttt
     8341 catactatag ctcttgtctt tacgccattc aattttttcc atttttcttc ctccgcgaaa
     8401 ttccatttag ttatttatta tcatacctct ttttgagtga cttggctaat cgtgttgaca
     8461 ctatttttca gtttgtgcta gaataagtga agtaaataaa tcgtacagat aacacgtttc
     8521 ggcgtgtcga gagagaggcg gtttctattt ttataataga aatcactctc tttttttacg
     8581 aaatttttta gaggtgatgt aaatgacaaa acaaaaacag ctgcttttag tacctgcagt
     8641 aattgcaaca gggatgatgt cttttgcggg cgtattgatc gagacggcca tgaatgtaac
     8701 tttcccaact cttatcagac agtttgattt aacgactgca caagtccaat gggtaacaac
     8761 gatttatctt ttgatgattt cgatcattgt tccgctgtct acttatttga atcgcaattt
     8821 tagtctcaaa aaactctttt tagcttcaaa tctgcttttc ttggcaggta taatgatcga
     8881 tttcttctct cctaccttca tggtcctatt gtttggtcga ttgctccaag gtgcagcgac
     8941 aggtatcgct cttccgttga tgttccatat tatcttgaca tttgcccccc tcaatcgacg
     9001 aggcgcgatg atgggtgtcg gtactttgac aacggccatt gctccagcaa ttggccccac
     9061 ttatggaggc attatgactt cacattttac atggaatcat atcttcctgt ttcttgtgcc
     9121 cgttttgatt ctttctttga ttatcggctg gtttgctatt cccgagatgg cagtacaaaa
     9181 aagtggttat ttggattgga taagcgtttt aggaatttgt cttttgttta gtggaagtct
     9241 aacatttttg agtacgttgg gaacagtttc cagctggatt gctttaatca tcggcggtat
     9301 tggctggttc cttttttact atcgaagtaa aaaagtggag catccactga tccgactgtc
     9361 tattctttca aataaaacat tccgcttgtt tttgattggc ttcttagttt atcagttttt
     9421 attacttggt gtatcttttg tcttgccgaa tttccttcag atcgttcaag gaagtagtcc
     9481 ttttgtcgct ggattagcga tgcttcccgg cgcagcggtt ggtgctttgc tttctccttt
     9541 ttccgggaaa atgctggatc aatatggtcc gaagaagcca atttttgctg ggctgattct
     9601 ttctttgatt ggttggctag cattattcct actcatagga cacgcttcag tgggtgtatt
     9661 gattgcttgt catgtgtttt atatgatcgg tatcggatta tcttacagca atatgatgac
     9721 caccggaatg aatgcactga atgaagaact acaaggagac gggaacgcaa tgttcaatac
     9781 cttgcagcag ttttctggcg ctgtggctac ttcattagta gcggtcatta tcaattacgt
     9841 ccagcatcat acttcccata actatgaagt gtctactaca ttaggatcaa aagcagcatt
     9901 aggcgtcttg ttgctgttgc ttctcgtaag ctttgctcga ttcgcctatt atctgttctt
     9961 tgctaaaaaa gcgtagattc catatacggc aggtgttgca tctgccgttt ttttgtgtga
    10021 aaatggttgt ttgtaaaagg aggctttttt atggaaaaaa ttgccattat cggtggcggg
    10081 atcattggta tgactctagc cagttactta gatacatcaa aattcaatgt tgctttattt
    10141 gatgaaggga caggacaggc aactaaagct agcgctggga ttatctcccc ttggttgtcg
    10201 aaacgcagaa acaaacaatg gtatcgtctg gctaaagacg gcgctgcttt tttccctaaa
    10261 cttataaaag atttccaact tgatcaaacg atttacgcac aatcagggac acttttgctt
    10321 cgacctgaaa aagatttagc tgaattggct gttcttgccg agaaacgaaa agaagaagcg
    10381 ccagaaattg gaaacatcga atggctttca cctgaacaga catctcaagc acttccgtta
    10441 ttgaaaccag cagtttcact gcgtatcagt ggtggtggtc gtctggatgg aaaagcatat
    10501 ttagaacatc ttggtcagcg tttagcacaa aaacaaatgg agcagatcca ggcaaaagtc
    10561 actttgcata agaagagcga ttcttggctc atcaagggac cgtttggaga atacacagct
    10621 gatcgtgtaa ttttgacacc tggcccggca cttaagcctt tattacaaga attaggctat
    10681 gctgcagata tacgtccgca aaaagggcag ctcttagcat ttcagacatc ttataagatg
    10741 agtcaagact ggcctgttgc tatgcttgac ggagaagctg atttcattcc tttcatggat
    10801 ggaaagatcc ttttaggtgc tacccatgaa aacgatcaag gctgggattt ggctcctact
    10861 agcgaagctt ataagggatt gactaagagt acagaacagt tcttgactga tccagatcag
    10921 ataaaaaact ggccatacga gttccgtgta ggtacccgtg cttatacgtc agatttttcc
    10981 ccatttttcg gcgtactgcc agatgatcca agcttactgg ctgctagcgg tctaggctct
    11041 tctggcttga ccacaggtcc ttatatcggc tatctattag ccaacttctt aaatactggt
    11101 cattggtcta cggaagatta tcaaaaggac atctccacct atattacgaa aaatccatca
    11161 tagaaaaaca gctttttcaa gtaaggatcc cgagcgatat tgcgcatgga ttacttcttg
    11221 aaaaagctgt tattttagtt caatttctga atcaaattct ccaaactttc ttttgcttca
    11281 tctggcaaga gatcttttcc tatctgagct tcaatgaatc gtaaacgaat atcaagtcgt
    11341 tgtttcacca gatttttata ggacgtatcc tcaaaagaaa caggaaaatc tggtataggt
    11401 aaatagtgga tgtcttcaaa tggaccaaac gacttgaatt ctgccgtttg ttgcacgatt
    11461 ctttcaacga ttgacaatgt cgtttcaggt ttgatttttt tatcatcgaa atatccagta
    11521 ttcaggacat agcaggctgt ttgctgtttc aaaaacaact ctcgaaaagc ttgatagtct
    11581 tccctaagag gatagacacg gaaaggatta gcaaatggtt caatgactag ctcatctagc
    11641 tgtctttttg tagtgatatt ttccgcgtct gatcgttttg ttgctaatgt tgcaccaaaa
    11701 gacgctgcta aaactgggtc attgatcttg ataattggcg gaagcgaatc atctttcatg
    11761 atccaaaaaa cagcatcgat cttttcgcta agatgatcga ctcggtcggg tgtcgcataa
    11821 cgtgatttga ctgtccgccc atttccgttt cgtatatctc ctgttactag gactttttct
    11881 cctttacttg tacatgtcac gcccacattc tgacaagtaa ggaaagaaga aatggccgga
    11941 tcatcagacg gatagtcttg tgttttatca aagtaagaag gttccaaggc agtagcaaaa
    12001 ccattttttc gagaaataac gaaagcatcg tcatgcaaga tcgaaacaga gtgaccttcc
    12061 gtatgttttg ctaaggtaat cgttgatttt ccagaaccgg acaacccaaa tacagccatc
    12121 gtataggtct ggtcattact agcatattgt ttcatcccac cgtggcaggc aataaagcca
    12181 ttgcgatttc ccaatgccca agcaagcgtc aaagtcgctt tttttaattc tccaaagtaa
    12241 cgtaatccta gcacagccgc tgtattatgg agagcatcaa acaaaatgag tccatttgga
    12301 aatgtttcat gtgtccattc gggatcacaa aagatataaa gatctccctc atcaaaggaa
    12361 acagactttt gataagtctc taagatcttc gaattcgctg gctgaaaatt cagcaaataa
    12421 gaatacaaat tgttctcaaa tccttctgga atcagcaaat gactttgcac agaaaattct
    12481 tcagataggc caacgattac ttttgtatgg taaaactggc gcttgcgact ttgatacaca
    12541 gcttctctta aaattttctc gtatttgctt tgttccttgt ctaagtcctc aaagatccgc
    12601 cgagcacttg ctgttcttcc cacaatgctt ccatcattga atactagtgt cctaacatca
    12661 gctggtaaat ctagttcttc agcatgtgag attgttaaat ctgtgatgat cgttcctgga
    12721 ctcccttttg ctagttgata agctgtcttc ctgtcaaaaa cttcatgaac attattaccg
    12781 taaaatgtcg tttctacaat cgatcgaata ctggataaca gtggatttcc acttgtgatt
    12841 tcgtttaatt cgagactctc ttttgtactc atggctcctc ctcattccct aaacaaaaaa
    12901 acgttttctt tattatacat tattcgagtt tttatttgta ctgctgcgct gtgggaagca
    12961 aacgagttat ttttcacaca aaaaaaccga gaacttgaat aaacaagttt ctcggtttca
    13021 tcattttcct tttatcggct tagtaccagc cgtttgctaa ccagaatgtt ttagcagcat
    13081 cccatgaacc ataacgagat gttacatatt gttctgctac acgttcttga ttggcagctg
    13141 aatagtcgcc gtttaagtat gaagcatcta attgataacg gccgatgtaa cgtccgttag
    13201 tagctgtgta tgaaccgcct gattcttttt gtgcgatcca ttcttttgca gagcttgaag
    13261 ttggcgctgt tgcagcagct ggggcagcag gagctacttc aactgtttca acaggtgcaa
    13321 cgtatgtatg ttcttgcgtt gctgtttcag ttgtagatgc tgtattttct gttgttttgt
    13381 tttctgttgt tgctgaagaa tcatttgaag ttgggattgt taattgttca ccaacataaa
    13441 tgcggttgat gtttgcgatc gaattttttt cagcaattgc atcgatcatt gagttgtctc
    13501 ctgcaaattt ttgtgagatc ttagataatg aatcacctga ttttactgta taaacttcat
    13561 cagcgtgagc atttgtagtt cctacaaaca ttgcagtagc accagcagca aaagttgtac
    13621 ctaaaacaat tttcttaaat gaattcatat taaactcctt tttttctccg ttttttattc
    13681 tttcgacgct attaacttta tcatttagaa atatttcata ggtaaaagaa acatgacatt
    13741 taatgacaaa ataacgaatt atttaatatt tgtaacattt a
//
LOCUS       DARBDN010000068        13683 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000068 DARBDN010000000
VERSION     DARBDN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.068"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..1404
                     /locus_tag="SCH06_001985"
     CDS             1..1404
                     /locus_tag="SCH06_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEG1078537.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1753..2385
                     /locus_tag="SCH06_001986"
     CDS             1753..2385
                     /locus_tag="SCH06_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HEG1078538.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2973..4412
                     /locus_tag="SCH06_001987"
     CDS             2973..4412
                     /locus_tag="SCH06_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1078539.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4707..4925
                     /locus_tag="SCH06_001988"
                     /pseudo
     CDS             4707..4925
                     /locus_tag="SCH06_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5174..5389
                     /locus_tag="SCH06_001989"
     CDS             5174..5389
                     /locus_tag="SCH06_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078540.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5606..5862)
                     /locus_tag="SCH06_001990"
                     /pseudo
     CDS             complement(5606..5862)
                     /locus_tag="SCH06_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6049..6960)
                     /locus_tag="SCH06_001991"
     CDS             complement(6049..6960)
                     /locus_tag="SCH06_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1078541.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6979..7983)
                     /locus_tag="SCH06_001992"
     CDS             complement(6979..7983)
                     /locus_tag="SCH06_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEG1078542.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7980..10103)
                     /locus_tag="SCH06_001993"
     CDS             complement(7980..10103)
                     /locus_tag="SCH06_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEG1078543.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10108..12555)
                     /locus_tag="SCH06_001994"
     CDS             complement(10108..12555)
                     /locus_tag="SCH06_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1078544.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12542..12931)
                     /locus_tag="SCH06_001995"
     CDS             complement(12542..12931)
                     /locus_tag="SCH06_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1078545.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12991..13494)
                     /locus_tag="SCH06_001996"
     CDS             complement(12991..13494)
                     /locus_tag="SCH06_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEG1078546.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13507..13668)
                     /locus_tag="SCH06_001997"
     CDS             complement(13507..13668)
                     /locus_tag="SCH06_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078547.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4204 a         2699 c         2501 g         4279 t
ORIGIN      
        1 atgaaaaaat ctttaaaact tgcatcagca gttatattaa tgtcccaact ccttatagca
       61 acacctttcc atgtgttggc aagcgaaaat tcaacataca aaattgcaaa agaaagaacc
      121 gagacgactg aaatgagtaa ttccgatgta acagcagaga gtagtgaact tttgacaact
      181 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc atcaagtgaa
      241 agtagtacga cttcaaatgc cgagtcttca acaacttcgt caagtgaaag tagtacgatt
      301 tcaagtaccg aatcttcaac aacttcaagt agtacaagtg aaataacttc ttcgaaagtg
      361 acaaaaccaa accatataga atcttcaaaa aaggaagcgc caaaaacgga aggacaaaca
      421 aaaacttttt cgacaccaca gcaaatagaa tcaacagaat ctttccaatc acaaccaata
      481 ctatctggta atgaagaaat tcattttgac aaaaatgaat ctgtagaaaa ttttattatg
      541 aaaattggtg agtctgcgag aaaaattggt cagaaatatg atttatatgc ttctgttatg
      601 attgcacaag cgatcttaga atctgccagt ggtcaaagcc agttagctca ggcaccgaat
      661 tacaatttat ttgggataaa aggaacttat aatggaaact ttgtcattat ggtaacaaac
      721 gaagatttgg gtaatggaac gctttatacg acccaatcaa aatttagagt gtatgaaaac
      781 tatgaggaaa gctttgaaga ttatgccaaa ttattaacta agggaattag tggaaataaa
      841 gatttttatg caggagcatt aaaagctaat agtaaaacat atcgagaagc aactaaattc
      901 cttacaggac ggtatgcaac agatacacaa tactatttga agctaaatga attaattaaa
      961 acctacgatt taaccaacta tgataaagaa gttaaaggtc cacaaatgag taagactgga
     1021 taccaagtgc ctattcataa ttattcaata accagtttgt ttggaaatcg tggaaatgaa
     1081 tttcaccgag gacttgatat ggcagctaca cagggtgagc cgattcatgc agttaaagct
     1141 ggtaaggttg ttaaagcaga gtttcactac tcttggggaa attacgtggt gatacaacac
     1201 gaagatggat caaccgcgtt atatgctcac cagcaacaat acctagtaaa aactggagat
     1261 aatgttttgc aaggacaaat aattggctat gtaggaagta ctgggaatag tactggccca
     1321 caccttcatt tggaaatttg caaagatagt agtctttctc agagcatgtt agttgatccg
     1381 aaaaccttat tattcggaga ctaaaaaagg taatcaatct gacaaagtaa caagaaaatg
     1441 gttggattct tagacctttg atcaggatat tgagactgga attgatatct cgattacgat
     1501 gggtttgaca aataaaacaa gtccattatc gaatatcgag tgtattattg ccgtctttat
     1561 gctcatattt tgagcaggtt tcactagatg aaaacaattt atctatcttg aggatttcgt
     1621 gtacgtatcg ttcagtcttg tattgtaaat tagtcataaa atcagactaa gaaaaattgg
     1681 aaatattttt ttctgattta ttaaaagtta attgaaatta tatggtactt ctttcttggg
     1741 agggtaggtg cagtgaagga aagatatggt caccttactg ttgttgagga gattactcat
     1801 aatggatata aaaaatatcg ttgcctatgt gactgtggga atgaaacgat tgtatatcga
     1861 tcaaacttac tatcaggtag aaccaaaagt tgtggatgtg gaaattataa aaataggcat
     1921 aaatataaaa atttgacaaa taaaactttt ggtaagttag ttgcaatcaa gccaactaaa
     1981 ctgcgaagtg aaggaactgt tgtttgggaa tgtcaatgtc tgtgtgggag aaaaaagtta
     2041 gtatcggcaa agcgacttct aaaaggtgat gtaaaaagct gtggatgttt gaaatcaaaa
     2101 aagcatcaca ttgaaaataa aaaattcgga ttacttactg caaagtatcc tttggacaat
     2161 aactgttcat ggaaaacaaa atgggtttgt cattgtgagt gtggcagtat gtgtgagata
     2221 agttatagta acttattttt tggacatact caaagttgtg gatgtttaaa aaggcaagaa
     2281 acaaggacat gtgttgaagg gacagtaata gagtgtctaa cgtcaaaatt accgaaaaat
     2341 aatacaagtg gtgttaaggg agtttatcgt tctaaagaga aatagattgc gtatataact
     2401 ttaaaaaaaa agaggtacta tttaggatcg tatgattcta ttaagagtgc agctcaagct
     2461 agaaaagatg ctgaaaataa attgtttcaa cctttgattg acaaatatcg aggtaatcat
     2521 taattattgt ggataataat taacagtgat atataaacat ctataatata ttattcatac
     2581 tattgatatt tagtataatc ctatggaatt gaatatcata gcaatgtatt tgaaaagcaa
     2641 attggaaaac aaataggtgc aacaccataa atatgaaaaa attgggaaaa agtagaatgg
     2701 aaatttgctt acgtctcacg agatagctca cactattaat ctgaagaaca atgaagtcga
     2761 cttttagaaa ttgctagaag aaagtaaagc gaattatcac tagttactat agagtaagtt
     2821 caaataaagc atctccaact tacatggtta catgaggata tcaaatcgaa attactcaag
     2881 cttcctatgg ctagagtcgc gagaagttgt tgggcagtag acataggtta tattgttctt
     2941 agctacacga tcattagaaa ggaaatccta ttatgtatag ttatcaagaa gatgcaaaag
     3001 tccaaaaaaa tcgctggtgg attttgattg ctatatctat gtttaccttc atgtccacat
     3061 tggatggcag tattgtcaat attgcactac ctaccatctc agatgatatg ggcataccaa
     3121 tgaatcaagc ggaatgggta gtgtccgttt atctgatgat tgtctgttct tgtttgttgc
     3181 tgtttggtaa aattggcgat agccgtggga aaatcaaagt atttcggatt ggtacgctga
     3241 tctttgtctt gggatcgctg ttgtgtgggt tcaatcattc gctaggtatt ttattgttcg
     3301 cacgggtggt acaagccatt ggtgctagta tgactatggc tacaaatgcc ggaatcatca
     3361 cggaagtctt tcccatacat gaacgtggtc gggcattggg agcaataggt gcgtttgttt
     3421 cattaggctc gattgctgga ccaggtcttg gcggcttgat tttgtcccaa ttttcttggg
     3481 cgtacatttt ttggatcaat gtaccggtgg gaatcgtaac gatgttgatt gctgaaaaat
     3541 tcttaccaaa agatatcacc atgagcggcc atacaatcga tggagggggc tttgctgcca
     3601 ttgcggctac gattatcagc ttttttggag caatcttttt ggggcaagaa agtggctttt
     3661 tccatccagt cccccttgta ctgttcgtaa tttcagtgat tgcctttgtc agctttttaa
     3721 aagttgaaaa gaaagcagcc tctccattga tttctttcgg tatttttaag aacaagattt
     3781 ttaccatgag cttgattaca gccttgttga ttttttcttc caacttcttt gtcaatgtag
     3841 tgattccttt ttatctgcaa aatgctcgcg ggttgagtcc tagctatgct gggctgttga
     3901 tgatggtctt tcctttgatg atggtcgtcg gggcgccttt aagcggctac ctgaccgacc
     3961 gggttggccc ggagattttg gtattagtag gcttgggctt attgtcggta acccaggtca
     4021 tgtatatgtt tttgtcagtg gactctcctt tgtggctata cattgtcgct actgccatca
     4081 tgggtgccgg caatgccttg ttccagtccc ccaataatac gatggttatg agctcggtca
     4141 ctatcgaaaa cttgggactg gcaggctcga tgaattcctt tgcccgaaat ttggggatgg
     4201 tcagcgggat ttcgctttct acgacggtct tatatcaagc gatgtctgct aagatgggcc
     4261 agcaagtaac taactatatc gcaaatcggc cggatgtctt tttatatgga atgaagatta
     4321 cctttttagg cagctttgtt ttgtgttttg ttgccttttt cctgactatc tggcgtatca
     4381 aaaaacaagg aggtattcag aaaaatgtct gaaaaaacca ctgttgaaga atttttggag
     4441 gcctgcgtat gggtgagtgg gatttccatg gatgatggaa gatgaagtga acttctaaaa
     4501 gccgaaaaac tcaagtatta tcttcaaaat actagtgctc aatgagatgc ttgatttgat
     4561 cacaagaaga ctgcgaaagc cgctggcaac cgcaagctag gtatcccacc gatggactac
     4621 gttttagagg ctactggtta tgaatacgga gccaacgctc tcatctgcat aagaatacat
     4681 cacccagatt atgtaaagat tttcgatact tctgtcaaaa aatcattaag atagataaat
     4741 gatttccgtc tagtcaaatt ggttcagaat gtagacacac agatggtaag aagtcactca
     4801 caattcgaga atggacttgt cctatttgcc gtatacatca taatcgaaac gtcaacgata
     4861 gtatcaatat tttgaccaag ggctatgaat acaagcattg ccttagaaaa catcaagaac
     4921 cttaggaaca acggggatag cttggttaat aagagatacc gctgtttagg cttgcaagta
     4981 tactctttta tcaagaattc cgtggcttta gtcatgagag gcttaatact atgaaaattt
     5041 tctttagcat ttttgattta ggttcctttt ctaattataa taagatgacc actacagtaa
     5101 cctactgaaa tatataaaca gccactgtag taccattttc aaagtagtct atgagaggag
     5161 aatcttcatt cttatgaacg ctggaattgc ggatatgaat ttaataaaaa aaacccttaa
     5221 tgattttact tccaattcaa tatcaaaagg tactggtatc aatttaagca caataaaaaa
     5281 gctgaaaagt ggtgaaagat cagtggaaaa gctgaatctt ttagatgcta taaaaataac
     5341 ggaatttgct atgaaaaatg gaaaagctga gattgaaata tggagataat tatcgtctag
     5401 tgaattactt gccacttagc tgaatttaac gatccttggt gcttgaaggg ggagattctt
     5461 gggaatagag catacttgca agcctatgtc tttactaaca acgatatctc ttattaacca
     5521 agctatcccc gtagttctaa ggcttttact tttatctaag caataatcgt attcaaagga
     5581 aatttttgac ccttagaaag tctcatttta tcagacgtga gcttaggcat tgctgaattt
     5641 tgttaattcg gttttaggtt gtgctttgag cataatatga aagtattctt tatcacgatt
     5701 tcattcatct aaggtaatgt gatgtgattc tgaaattctt tcaaaggcag tttttgcata
     5761 agctgacatt acatcatcaa tgacatgttt acaatgtttc actactaaaa taagggggta
     5821 accaagaaga aaaactgaat gattatttgt atctaattcc atggtatatc aaccatttcc
     5881 tatatagact gattatgaca tggattaaaa taaaaaggca ctatgtctta attgtcggtt
     5941 ttcgagttac cgaatggcat tcatcaccca cctatagagg atgggcgact tctgcctgaa
     6001 ataagttaca ctacttataa cttctaataa aattagattg agtcattatt atttaacatc
     6061 aacgattttc cagtttccat ttttttgtaa tactaatttg tactgaaagt agctagtggt
     6121 ttttgataca ttatcaaggt attttatctt tgtactcact agaaaatttt ttccgttttg
     6181 tagataaact ggattctcta actccgaaaa ctttaagtca atattgattg gtcgcatcgc
     6241 accattttca acataatact ccaattcttt ttcagaagct gatggataaa gtttaaaaaa
     6301 tgtttctaaa aaatcggtga tttcttccgt tgttttggca tcaatttctg aatcgttttc
     6361 tacttgtttt gcttcatatt ttgccttgtc tggctttcca atcattgttg gcaaactagt
     6421 tactaaatga ttcctgtttt catcttcaaa gattgtcact cgatatgcag aagaaattga
     6481 ttgcgtcttt tttccctctg taatatgttg ctccactaaa aatgaaacga caaattcttc
     6541 cgagtgtttt tcaacatcta gaatttttac agattgaact tcggaactcg tgggaatatc
     6601 tgctcgaacc atatcttgga ttaaagcgag accgttttct gtaaggtact gttcgagatt
     6661 actcattctc ttttcaattg cttctttgtt atttttccat gaaaaatatt ctttcgcaaa
     6721 atcctctgta aaactttcaa cgccagaagt attcactacc ttctctttta taaccacttt
     6781 ttcatgagtt gtatgttgat caatggcggt gaaattttta taaacgccaa aagcaagact
     6841 acaagacaat aaaagccaaa gggcaagcac catttttcga tgcttaccca cggatacaac
     6901 tcgttctttt ttcttttttg ggctcttttc cttttgattc cgttcaattt ttatcttcat
     6961 tctttttcct cttttctctt atttgtatcg gccagctccg ataagatgct gccgccaata
     7021 gttttccgtt agattcgtcc accccactgg atctcctgca tgaaacatgc gattctcccc
     7081 tgcgtaaatg cccacatggg tcacataagt accggcatca taggttgaat gaaagaaaac
     7141 taaatcacct ggtttggcat cttttagatc aatatgagtc atggcatcat attgatcctg
     7201 agccacccga ggaagtttca ggtcaacttt ggcataacac cattgggtca agccactaca
     7261 atcaaacccc gtttctggac ttgagccacc aaacacatag gccgttcctt catacttaaa
     7321 tgcctcatca aaaatttctt ggactatttt gtcatcaaac tgagttgtag ttaggtattg
     7381 cttcactaat aaacagtaaa acatattgcc ataattatac cgccacccac cattttcctt
     7441 aatcgcgatt gggttggggt aatcgacttt ttgaccacct gatttttcct ttgaaaaaga
     7501 ttcagctaaa gcaaaactat gcttcttccc gtttttcccg acatgatcta gatacccgcc
     7561 accatagtta taggcctgaa taatactatc ttgatcacac cctagttctt tggaacgctt
     7621 aaccaaagac gcaaaataga gacagccttg tttgatggat gcctcggtac ttaatgaatt
     7681 aggtggtaat ccggctgact cagaactttg cataacgtct tccattgtgc caccagattc
     7741 cacttgaata atcgccaaaa gaattggaat atactctgtt atatccgatt ctttggcata
     7801 cttttccacc attgcacggt gtttcaatac ttcttctgag acactagttc cgccaggaga
     7861 agtgccagaa ctaccatttc cctcactgtc ttcaccaaac aacaaaccca cacacatcaa
     7921 aatacccata aaagagatgg tcagaaaagt taatgaaata acacccactt tcttcaagtt
     7981 cattttttct cacctgacct tgattttgga cgatggttca ttcttttttg tactttttga
     8041 ttggtctgct ttggcagagt ggacctctgt ttcacttgtt ggaaagaatt tttcttactt
     8101 gctgattggc ttttcccttt tgaaatgatt tcttgactag ttagttttcg tttgatttcg
     8161 ggattcagat ttgctctcac aatccgcttt ggtgcttctt ttttcagcat catatctttc
     8221 tgaggttgag ctgctttatc tattggaata ttcgcccttc tttttccctg acgatttgtt
     8281 gcttcactca gtatcttgcg tttttcgtcc attttcgcat ttcttcgttg tcgttgtttt
     8341 tctcgcaaat ccactcgatc cgctttttct tggaacagtc cgcgcttgaa ttcttctggt
     8401 gcttttttcg acttttcgat tcctttatgg agattgtatt tcaaattcgt tggcgtattc
     8461 cttacctgat cctttacttg tttagtctta tctttcacca aagcttgggt atccaaaact
     8521 ttgccgattt ttctcccagc caaattcatt cgggattgtt tcttattatt tgaaactgga
     8581 ttctccttag ttaagtcaga tagtatttcg tgatcgttcg gtaatcgtga attctttcgt
     8641 agagaagaac cggatggctt aaatttggat tttgattgtt cctttgccaa cttatttccg
     8701 actgctgcac caccaccaaa agccaaagct cgtcccacat ttcgattgag ttgccgcaat
     8761 tttcgattca ttaacatttg cggttttcgc atgacgcgtc ttcccattga ctggctatca
     8821 ttactctgga ggttgaacat actcataatg tcgcccaatt tgaaatagat accggcaaag
     8881 gtcacaattt gcagaaaagc aaccatgaaa aatggatagg ttgccgaaat attgaaaaac
     8941 atcgtggaga tgctaaatgc agtcgtaatc accaaagtaa cacccgctcg catcataatc
     9001 gtattgaata aacgaataat cgccttcttt cctaaacttt cataagtcgg caacatggac
     9061 aataagaaac taattggcag aaacatcgca aagataatga agagaatttg cgagaacaac
     9121 ataatccctg ttagaagaaa aacaaagaag gaaatgccaa tattgaacaa taccaaaaag
     9181 accacggtcc ctaaacggtt catggtcttg gtaatactga gattcgcatt gtcattgtct
     9241 tcaatctctg ccttgaccgc ttcttcccga tctttgcctt tgttttcatc tggactcaca
     9301 gatagaatct tgttgacccg gtcttcacca atttcttcta tgttggaatc atcaaattgc
     9361 agtagtaacc aaggttgttg gacttgaatc gaaaacaaac tatcccgaat caaatccaca
     9421 ctatcttttc cttggctttc tgaattgggt acaacgatct cggttccaag ggtaagggcc
     9481 gcttcactaa catctgagct aaagtcattg atttttgtga tataggtagg cgcataagca
     9541 atgaacgaac ccgatagtag aaaaatcatc acaaaattaa tcacggctcg aactgctttc
     9601 gtggtttctc gttttaataa tccggtatac gccacataca cccccagagc taaaatcatc
     9661 aataatagaa acccaaaata aaatccggag gtctggagtc cattttcagt aataccagcc
     9721 aatgtttgga tattctttcc aatactttca gccgtatccg aaatgaaatc taatttgtaa
     9781 gcctcttgaa ccacataacc cgtggcgttc gacaaataca aactcaccgt ccaaatgaaa
     9841 ttagtaatgg cataaagacc atacatcacg cttttcccta agccatcacc ccaattccaa
     9901 ggcaaccaat cccaagagct atccacaaag aaatctagtt gatagttgtt cagtgaatat
     9961 ttggaatata gatttcctgc ttcaactgta tcatcaacta gccctgtcgc ctcggctacc
    10021 gtaccaacta aactcaatag aactatcaga gtgagtatgc taataaaaac gattcccaca
    10081 atccgaaaaa gtttcttttt catcccctca ctccattctc tcttgaacag gtggacgggt
    10141 atcaaaggca tggaagagtt cttcaaagac tggatgtacc tgaaccacgc ctacccgacc
    10201 atacaaatcc tgcatcaagc attggccatt ttccaaatct cgtaggcgtt tttgattgct
    10261 ttcatcttct cgatccaagc caaagaattc caaggttttc ttgatttcat gaatatcggt
    10321 actgcgaaac gcaaacttca acccgatatt attcttcaag cgttcatcca gtaaatcatc
    10381 actattttgc gtgacaaagt aaaccccggc attcatagcc cgcccagcac gaacgagctt
    10441 attcgataat gttttccctt gcgctacttg aagaaaactc cacgcctcat ctaagtctac
    10501 aattttgaag atttctcgat tactatggat aaagtccaag gcaaaagtgg aaatgacgat
    10561 tagcatggaa acactaagca attccatggt ggtatattct tcaaaagtgg tttctgcatc
    10621 tggtaaaacc aaatccgcta cttgaatgat atttaactgc ctatctaaac taatcgactg
    10681 ggtaatcgaa ccatctgaga aaagcaaatg ggcaaaatca taatcggtaa aggactcgat
    10741 gtgatccgcg atattttccg caactggtga gccttctttt cgaagctcat taattacttg
    10801 taataatccc cgttgattgc tttgggtaac cgtccgaatg gccttacgca acactggaaa
    10861 cttctcccca tctcgactag aaattcctgt taaaaaggtc agaatatcaa ttgctagact
    10921 ttcagaatcc ttctttttct ccataatcac ataaggatca agtaatcctt gattttttgg
    10981 cttactagtt aagttgagaa tattgatttc atccgcaatt tctggcaagg tttctttcca
    11041 gccaccccgt tccccttttg gatcgacaat cacagcttgt ccaccaaaaa ggacggcgta
    11101 ataaactaag agattgttac taaaggactt tccgccaccg agtgaaccga ggaatgccgc
    11161 tgctagcgca ttggtaactg aatccttgac cccttgtgag gccaatgccg gtttcaggta
    11221 aacattgcgc cccgtatcta cgttataacc aaagtaaatg ccttccaact cccctaacat
    11281 ctgagtggcg ccaaaaccaa gtccggcgag aaaatcagac gtaacatact ggatataatc
    11341 attcatgtat cgcttactag aaggtaagaa ttcttcatgt agccccatca tatcgccaaa
    11401 aggccggact agttttacat tggtatcatc ataaaaatct agcacttcat cacaccggcg
    11461 ctttagttca tctactgatt cggcacttac tcgaaccaca tagctcagtt tgtacatgga
    11521 ttctttggac tgatccaagg tagtttccaa ttcatctacg gaatccaatg catctaagac
    11581 attggaattt gtttcattgt cagattgata ggcatggttg tccaagtctt ttaattcctt
    11641 tttcttattg cgaacggtag caagtgcctt tttgttcgtc acaatctcca cattcatact
    11701 agtgtcaatt gggaatgtaa attgttgttg ctggtaatag aaaagttctg aggagggaaa
    11761 ctccatttcc cccacaattg tattaattgt taagtacgct acatatgatt catgattctc
    11821 atgttccatg cataagtacc ggggcttttc ttcaatcaaa caacgactgg gacgtaataa
    11881 gtcgtaacgt ttcaccaaag tttccgactt cagctttttc tttggtagct gaaattcata
    11941 ttcttcaaat ggtgtaccct tttcgccata gatatgttca atcaaataca tcagatcact
    12001 cggtgtgact cgtctgactt taaatcttcg agccaattta ctttccatta gtttttcaag
    12061 cttggtatat cggcgaattt cttcattgga taaggaaaca aaatcgccca tcaaatgatg
    12121 attcactcca tagacaaatt cttgaaagcc ggagaagaaa gatttcttga gattctttag
    12181 attgacctct tcatctgtcg caatcagttt gaagccaata aaaaagcgat aatcaatctg
    12241 actatcgcca atcatggata ctaatgcctc tgtctgtaaa tcaattcgtt gtttcgctac
    12301 ttctgttaat cgcccggtaa tttccttttt tgatcgttct tgcgtggcac gaatactact
    12361 ttctgtggca atttgtaagg catgaatctt gccttcacga ttttgcgcaa tcaattgacg
    12421 aaagttatcg tggacttgat atttctgttc aggtgacaaa aaggagtaat tgtaaggtat
    12481 taactcatag taggcaaaac attctccctc ttgattaaag acaagattat tttcaatata
    12541 cttaatcggg tacatagttc acactcctta ccagagtaat gggttcgtcc catcgtttct
    12601 tctgttcttt gactttcttt cctgcgaaag tgaccttaaa tcgtaagtga tagctaataa
    12661 aagatcgtaa aaatcccaat ggtttcttac cgtcaaacgt tttttgcgac atgaaccaag
    12721 taactgccac cggtatacct aagtatttta aaaaggcccc ctctatcata gatagtggag
    12781 gcacatgggc aaatacgatg acaaacagca aggataaaac aaaccaagcc atctggttaa
    12841 aagtcacagg aaaaggcagt tgaaagtcat taattgcata aatgaccttt tcaactgccc
    12901 aaatactggt gtagcttttt attttcttca tcaaatcatt cctttaaaaa gaaggatagt
    12961 ttagaaatca actacccttc aataattttg ttaatatgga tactcaaaaa cacctcgact
    13021 cgttaccaaa taattgcctc caatctccaa gtctctacca cacgcatcaa aatcaatata
    13081 cgtcttcaag tgttctggta cttctccaaa atcaccagct tctacaatca agaaatatgc
    13141 tacatcactc atatcatcgc aatctggata atagataata tcatccacat gctctaccat
    13201 ctcctcaaaa gaattgaaga aagcatgttg aatctcagaa gcaacttcac caactggcgt
    13261 tccttcaagt tcctccgcta agccacacaa ccgattaatt tcctcaattg gcgtatactc
    13321 atcaatctca aagggaagtt cataatcatg aattgcatat tcctcgtatt cgtcatttaa
    13381 cccaattcgt tctttcactt catcaaaatc gacaggtggg gtaaaccacg cccccaccaa
    13441 ttcaccttcg ttatatttcc cgaggttcgc aatataaaca cgcatctgtt ccatcgtgct
    13501 tcccccttac gcaccgacaa ttcggttaaa caaactgagt aagacatcct tcaccccaga
    13561 agcattaaag accaatccga ccgcaatcaa agcaatcacc aaaaagccaa tcagtttgga
    13621 aaactcccgc ttaaatccta aaaacaaacc aatgaccaca attgccagta agactaagga
    13681 ttg
//
LOCUS       DARBDN010000069        13434 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000069 DARBDN010000000
VERSION     DARBDN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.069"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            85..252
                     /locus_tag="SCH06_001998"
     CDS             85..252
                     /locus_tag="SCH06_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEG1078548.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(314..2125)
                     /locus_tag="SCH06_001999"
     CDS             complement(314..2125)
                     /locus_tag="SCH06_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HEG1078549.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2122..2487)
                     /locus_tag="SCH06_002000"
     CDS             complement(2122..2487)
                     /locus_tag="SCH06_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HEG1078550.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2650..3045)
                     /locus_tag="SCH06_002001"
     CDS             complement(2650..3045)
                     /locus_tag="SCH06_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEG1078551.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(3063..4025)
                     /locus_tag="SCH06_002002"
     CDS             complement(3063..4025)
                     /locus_tag="SCH06_002002"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEG1078552.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(4025..4237)
                     /locus_tag="SCH06_002003"
     CDS             complement(4025..4237)
                     /locus_tag="SCH06_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEG1078553.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4258..4956)
                     /locus_tag="SCH06_002004"
     CDS             complement(4258..4956)
                     /locus_tag="SCH06_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEG1078554.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4976..5518)
                     /locus_tag="SCH06_002005"
     CDS             complement(4976..5518)
                     /locus_tag="SCH06_002005"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEG1078555.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5650..6654)
                     /locus_tag="SCH06_002006"
     CDS             complement(5650..6654)
                     /locus_tag="SCH06_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEG1078556.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6651..7640)
                     /locus_tag="SCH06_002007"
     CDS             complement(6651..7640)
                     /locus_tag="SCH06_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEG1078557.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7637..8443)
                     /locus_tag="SCH06_002008"
     CDS             complement(7637..8443)
                     /locus_tag="SCH06_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078558.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8609..9565
                     /locus_tag="SCH06_002009"
     CDS             8609..9565
                     /locus_tag="SCH06_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1078559.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9642..10160)
                     /locus_tag="SCH06_002010"
     CDS             complement(9642..10160)
                     /locus_tag="SCH06_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEG1078560.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10248..10397)
                     /gene="rpmG"
                     /locus_tag="SCH06_002011"
     CDS             complement(10248..10397)
                     /gene="rpmG"
                     /locus_tag="SCH06_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEG1078561.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10625..11071
                     /locus_tag="SCH06_002012"
     CDS             10625..11071
                     /locus_tag="SCH06_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEG1078562.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11266..13161)
                     /gene="asnB"
                     /locus_tag="SCH06_002013"
     CDS             complement(11266..13161)
                     /gene="asnB"
                     /locus_tag="SCH06_002013"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HEG1078563.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4189 a         2843 c         2288 g         4114 t
ORIGIN      
        1 aggtttacaa acaaacgtaa aactagcctt tttttctctt ttgttccata atagatataa
       61 caaataataa atgaggtgga ttcaatgaaa aaatttgtat ctggaatatt agtaggaagt
      121 ctggcaacag ccgctgccgt tgctggtttg gttgcttctg tgaaaaaaac agtgatcgat
      181 ccaattgacg aaaaagaagc aatgatcgaa gaaaaccgta aaaaagcaat gcgtaaacgc
      241 gtttctcgtt aataattatt taaaaatacg catgaagact ttctaaaaaa cagataagtc
      301 atcatgcgta tttttatttg tcagtcaata taagttgtgc tattttatct gcctgtctca
      361 gattccatgg atctgtataa ggtctagcta ctgctgcagt tagccaatcc acaccttcaa
      421 caggtattcc atagcaataa aagtcagact ggatttcccc tgaagcatca atcacgcgat
      481 tcgtacctcg ctcaacatct atagcttctg aatgataact tcctgtatta tctgaaaatg
      541 aaaaagggcg aacaagtttg ttttccttca aattttttat gacaggatta cttgaacgag
      601 aaaagcttgt ttgtggcaat cgagcttcaa tcaaatagcg actgctgatt tctttatctt
      661 gtagagaaat aacatagcgg ttgtgctttt gctgaatatc aaatggcggt tcgatcaaat
      721 gaaaaatacc cgcatctatc agtgctgcta attctttcgt ccgaatgatt ggcggaccga
      781 tcgttaaaaa gctatttaga tgagtaaacc atccccatag tatttctttg tattccttag
      841 cagaaaaaac gtgccattca atagcctgcc ggattggatc acgccagtct tttaatgcat
      901 caaatgttga agcaaatgct cctgtgcaat tgcctttttc cgcttctttt atctgccctt
      961 caataaatat tcggctagct tctgaaaagg gctcattctg ataggcaaga ggagtttcta
     1021 aatacgacca atcccatcta taagggatta gtgctggatg ctttccgaga cactcctctg
     1081 aagagaggga gagaaaatca tgctcaaaat ttttctttgg aatcggcaag tgatattctt
     1141 cgatgatttt cttgtaataa aacaactcaa cgtctttttt cagatagtca aaaaatgttt
     1201 cgccagtcaa aaatcccgac tgatgccatt gctccaggtt ttcttttgtt agtaaccgtg
     1261 gccatgccat tgctccgcct tgcttttgat ttcttcctcg agggtaataa gggagccccc
     1321 ttcttgatcc actgtataca atcggttcct tgcctgatgg atgatagacc agttttccct
     1381 tttcgttctc gaagcgccct cctcttgata ctgtaaacaa tccgacataa tcaaaaaaac
     1441 ttaagcctag acctcttaaa aagacatttt ctttaggcgg tatcttcgaa agatctacat
     1501 ctgcaggatt agaaggaagc tgatacagta aaacattttt ctttgcgtag tctacccaca
     1561 ctctttcttc ttctgtctca tcattttccc agtgaccgct tgctaaaaca agctgatcga
     1621 tagaatagct ttgctgatct gtctgtaaaa gataaccatc ttttcttttg cttacttttt
     1681 ttactaaaga ataaacaaac tgaatagaag ctggaaattc ttcttgcaac tttgagaaaa
     1741 accagcgttg atagagtccg tataaacatc gagtagattg ctgatctttt tccagacgat
     1801 tgatttcttc tataattagt tgcttatttt tggttaccgt ctgttcgata taatctgtag
     1861 caggtccttt actccattga aacaagttgg gtccctgtgt taccaatcct ccactggaca
     1921 atgtttcatc tgtaaaaagc gtcacttgtt gagaaacaga attcattaat aactccggtg
     1981 gctgattcaa ccgccaaact cgacctccag gaccattggg atcgaaaaga aaaagttcaa
     2041 gagaatgtct gtcctgatta ttatggagaa tcctttctgc tacacttaat cctctaggtc
     2101 cggcaccaat gatccctatt ttcatttgca tgcctccatt tcgataaatt ttttcaataa
     2161 aacagcatgg ttctgatgtt cattttttgc accataaaca aaagtaatga ctggatgttc
     2221 tttcataagt tgactgagtt taaaaatagc ttgcttcttt tcttcttcga aaatcaattc
     2281 ttgctggtat ttctttgcaa atgaagcaaa tcgttctggt acatggtcaa aagttttgcg
     2341 tgcttcatta ctaggtgcaa tttctttcaa ccacagatct aactgcgctt tttcttttga
     2401 aattcctcgt ggccagaatc tatccacgag tattctatag ccatcctctt tttcagcatc
     2461 aaggtaaaca cgttttaatt tgatcatagt tgtttccttc tttctacctt ttcgcttagc
     2521 ttatatatgt agataatagc acaaaataaa aaaaatgaac ggcacaacta tccattgcgc
     2581 cgttcatgtg atcttggtca aaatctaatg attgattcgg tttttaaagc tgtcatacaa
     2641 tcatctgttt tatacttttt tacttttgat ttttccagac catccgtcat atccaccctt
     2701 aagtaaataa atctcttgat aacctgcttt acgtaattta tttgctgtac ggatgctcaa
     2761 acttttcttt tgatcgtaaa tatagacagg ctggtctttt cgaatagatc ctaatgaatc
     2821 tttcaaaaca gtgtaaggga tgtttcttgc acctaaaata tgcccagcat caaacacatc
     2881 tttttcgcga acatcgatta cttgtgcttt tctcattcct tctcgaaatt cttcttctgt
     2941 caaagtcgtt gctgaacgtt tggccattac tcgtagatag acttcccaaa ggatgattgc
     3001 aagcacaatc aatagcaaaa tgatattaat tacccataaa accatgtaat gcctccgttt
     3061 ttttaagcaa atttcaaggc taatgaggca gcaccaatga caccagcttc attaccaagc
     3121 tctgctaatt tgatttttgt tgattctctt acttgcggga aagtaaattc tttaaaatat
     3181 ttctctacac ggctacgtaa aaattctcct gctgccgata ctcctccacc taacacgata
     3241 cttgacggat ttaatgtatt ccccaagttt ccgcaagcta aacctaagta gaagcatacg
     3301 cgatcaacaa ccatcaatgc aaacggatcg tcttcttgag ccatttcaaa gatatcttta
     3361 cttgttactt cttctccgtt gtctagcatt gctttcagtt ttgaatcccc tgcgtattct
     3421 tctgccaaga aacgacctag gcgtaccaca cctgtagcgc tagatacagt ttctaaacat
     3481 ccgcgtttac cgcaagtaca ttcgaaccct tcaggatcca cagtgatatg tccgatttct
     3541 cctccagctc cgctcacgcc gtgaatcaaa tttccgccag caacgatacc tccgccaaca
     3601 cctgttccta gagtaacgaa tacaacgtct ggatcgtttt ctccagcacc tttccatcgt
     3661 tcacctaaag cagcaacatt cgcgtcatta tcgatagcga atttgattcc tgttcctgcc
     3721 tcgatcagtt ttttcacaaa ttgaacttct gtccagttta agttatacgc accaataacc
     3781 gttccagctt cgctgtccac gcttcctggg gtacccatgc cgattccgat aaagtcttcg
     3841 gctttcatat tatataaatt caaacgatga ttgattgatt caatgatttc aggaacgata
     3901 tgcttaccat catccaaaat attggtatcg atgctccatt tttgctgaat ctctccttct
     3961 ggtgttaaaa ttgcaaattt tgctgttgtt ccacctaaat caatcccaat aatcttcttg
     4021 tccattacaa atttcctttc tttcggcttt cttcaattcg gtgctctctt tttaatatgc
     4081 gccacgctgt catgtatgta tcatgatcaa tcaaacggct atcatacaga ttacgcaatt
     4141 cgatagtcat taattcaatg tcatagatgc gtgcacccac atagataaag atgccaaatt
     4201 ttttgaacag ctgctgtaca tcatataagc tctccatctt taagcacttc cttcatatta
     4261 tacaagtaaa ccatattttt ttaaacccag taaaatacat attacaaaaa gaaatacaaa
     4321 aactagtgta gaaagaatcc tttggtgtat cgaatagctt gtctgttgtt tcggtagacc
     4381 caaaacattc cctaacacta atccgccaat tagcccaccg acatgtcccc aaacatctac
     4441 agaggtatcc agaagaccaa aaacaaatgt caacacaata aataaaagaa aatgtctgac
     4501 tagctgctgg atcgctgggt tatgtttaaa atgaaaccct aagataaaca acgcaccgaa
     4561 caaaccgaat atcgaagtac ttgcaccacc agacagaaca ttcgcttcgt taaaagcaaa
     4621 gcttgctgta tttcccatta tcccgctgaa catataaatc aagaaaaaac gccaatggcc
     4681 atagattgcc tcgatttgct gccccataaa atacagtatc agtgagttca ttacgaaatg
     4741 catcagtcca aaatggatga agattggtgt cactaaacgc caccattcat tgaagtgaac
     4801 aagataagga ccatacattc cggcataata agggatctca agtcgcggaa ataattccat
     4861 catgaggaag accgctgtct gtatccctaa aaaagcatag gtccataacg gtcgtcttaa
     4921 ccatgcacgc aattttattt gctgttgata attcatgaaa acctcccatt tcattttagt
     4981 caataaacaa ttgttggatc ttctgatcaa agctctccgg ttgccattgt tcattcaatt
     5041 gttcacgaaa aacaaggcta catgtttttt tatgaaaatt atttaaatac cggtcgtaat
     5101 aaccaccgcc aaaaccgatt cgataaccgg ctctattgta gataatacct ggtacaatga
     5161 ggagatcgat catctccggc aaatagagct tctctgattg tggctcaaga acaccaaaac
     5221 tcgaacgtac aagaacggac tgttcatcca tttcataaaa cgccatctga cgtttcggca
     5281 aagttttagg tacaactatt ttcttttgtt ctttttctgc tcgttggata accggctgtg
     5341 tatccagttc aaattcattc gataaagtcg tccctatcac ttttgctgac ttccagtact
     5401 cgctggcgaa tagctgttta tagattcgct gttctttttc ctttttcttg ccacttttgg
     5461 ccagattttt cagcttttcg attcctttcc ggcgtaatct tactttcaat tggtccaaaa
     5521 actcaccctt ccttctctca taaaatggta taggaaaaaa agaaaaatag caatcgaact
     5581 ttcaaataaa tgcataaata gaataaaaag aagacctaga aatgattggc cttccttttt
     5641 taatgaattt caactgttca gcgcgtgttt ttgtctgata aaaagtgcat acagaaaata
     5701 tggcgcacca aaaagggcaa tcaaaattcc tgtaggtact tccccacttg gtagaatcac
     5761 tctagcaacc atatctgcac taagcagaaa aatggaaccg aacaaaccgc tcagaacaaa
     5821 ggtccagtta ttttctttac gtacgactag cttcgcagca tgaggagcta gtagtcctac
     5881 aaaagataaa ctacctgtca ccgctacact accgcttgcc aaagcaacag ctaacaacaa
     5941 aaggattttt tgacttttag ccacgttaag gcctaatcct tgcgcgcgtt cttgaccaaa
     6001 tgatagcaat acaatcctct gtgcataaag tcctcctagc ggaattaaga taaccgccca
     6061 tggaagcaat gcccaaacat aaggccagct cgcaccccag attgatcccg ctaaccatgc
     6121 attcacaaat ccataatttt ccttagataa ttggatcgtg catagcaatg ttaatgcaga
     6181 aaggccggca ttaacggcaa taccggacaa taagattcga ttcataccca aaaagccatt
     6241 tcgatcatag gccgcaagat agacacagca agcagctaaa acaccaccta gaaaggctac
     6301 aactagcaat agaaacggca gcgaatagtg cgaaaagaaa cctaaataaa gcatcactaa
     6361 aaatcctgct ccggcattaa tgcccaatat actagaatct gccaattcat ttcttgttac
     6421 tccttgcaag atataaccag aaacgccaag acaagctcct gctaataaac tgatcagtaa
     6481 tcgaggaact cgaaattctc taacaatcag cgccaaagaa gatgattctt tccctatgaa
     6541 cgtggcaaaa agctgatcca ggtaaataaa aggcgtacca atcattaaac tacctataga
     6601 caggatgaca agtacaaaaa gcaagaaata gaacgtccaa tatatttttt tcaccgttgt
     6661 tccctcctta cttgtatcag taaaaacgga acgccaatca atgcaatgac taatccaaaa
     6721 ggtgtttcaa aagggggatt gatcatcctc gctgtaaaat ccgccaacat aaccaatcca
     6781 ccgccaacta aaaaagagac aggtagaaca taacgatagt ccgttccaac cattccgcga
     6841 acaactggcg gaaccaacag cccaataaat gaaacaggtc cgactaacga aacggcaatg
     6901 gctgctaaca ctgcaactag acagaaaaca atcaaccgcg ttcgtttagg atgacttcca
     6961 agagctaatg catgtgtttc actcaaatga atcaaagata ttgcttttcc taatgaaaaa
     7021 gaaaccaaaa cagcaagtat atataaagga aacaatactg ctaattgttt ccatgtgata
     7081 ttggcagctc cgcctacaaa ccaaaaagca agatcctgct gcagattaaa gaattgggta
     7141 agtgcttggc tgatagcagt aaaaaaagaa ctaatagcta cgccagctaa aatcagctgt
     7201 aaaggattca tgcccatttt cgaaaactgc aaaaaaccaa atacgagcaa agttacagca
     7261 aaagaacctg ccaatgacat tagaaacaca gaaaaatcag aagctttagg ccaaaaagca
     7321 aaactaaggg ccattgccaa cgaagcaccc gcgttgattc ctagtaagcc tgaatctgct
     7381 aaaggatttc ttgtcacccc ttgcatcaat gcaccgctca atgcaaaaca actccctaca
     7441 agaaatgctc ccgccacacg aggcaaacga atatttcgta tgatttggtg actttgtttt
     7501 gatctatcaa aatcaaacaa cgcctgccaa aaatctgctt tttccacagt cgctgcgcca
     7561 tttgaaagag caacaaaaaa aataatcaaa agaacaaaac agaccaaaag caggagtcta
     7621 tttttcttca tagtcctcat aattgatcct cctgctcttt tggcaacaaa tcataggtta
     7681 gaaaaactgg tttatttgtt cttggaagcg tgacaatcgt tgcatcaatc tcaaatattt
     7741 ttttcataca ctcttttgtg atcacttctt caggtgtacc ttctgtgatc aacttaccgt
     7801 ttttcattgc taataaataa tctgaaaaac gtgaagcatg attaatgtca tgaatcgaca
     7861 tcaagatcgt tgtttgtttc atttgattga tttcagtcaa taactgtagg atctctaatt
     7921 ggtgtgccgg atctaaaaat gttgtcggtt catccaagat caagatatct gtttcctgag
     7981 caagcgccat agcgatccag acacgctggg tttgtccacc agacagcgtt gcgatatccc
     8041 gcatacgaaa tccagctaga cctgtagcat ccaacgccca ctcaattgct tcatgatctt
     8101 gcgtgtccat gccactgaac agtttttgat aagggtatcg tccgtaagat actacttctt
     8161 ctactgtcat acctgtaggg tgttcactag tttgtgctaa taatgcaatt ttttttgcaa
     8221 gttcttttga actgtatgta gagatatcag agttattgac aatgatcttt cctgatttca
     8281 caggtagtat acgggtaaaa cttttcaata aagtagattt tccacttcca tttggcccaa
     8341 tcaaactagt gattttccct tcaggaatcg taacagacat gttttcaatg atttttttgt
     8401 tttcgtagcc ggctgcaatg tcagctgctc ttaatctcgt catttcaccc atcctttcgc
     8461 tgaaaatcat tctcaattat gacgctgttt caacatttcg tcaagcgcta ctttcatatc
     8521 tatagccaaa tgaagcggtt gacagcgttc gaaatatcag gaataataac caatgagaaa
     8581 gattctcaat tatgttagga ggaaagaaat gaaattaaaa acaaaagtat tcacattatc
     8641 tagcatattg ctgctggctg gagtactgag cgcttgctcc ccctcttcag ataaagaaac
     8701 agctacaact gccaattcga cgacttcatc caatagtact catacagtca cagatacact
     8761 tggacataaa gtagagattc caaacgcgcc caaacggatc atcggcagtt acttagaaga
     8821 ctatctgatt gcactagggg aaaaacctat cgcccagtgg actgttggca gtggttccat
     8881 tcaagattat ctgcaagatg atttaaagga tgtcccaacg atttcttatg accttcctta
     8941 tgagaaagtg ttaagctttg agcctgattt gctgttgatt tcttcttccg ctactgtcga
     9001 aggcgggaaa tacgaacaat atagcaaaat cgcgccaact tatgttgtaa aaaacggaac
     9061 agatgtcaca tgggaagaac aactaaaaga tgtcggcaaa gctttggcaa aagaaaaaga
     9121 ggcagaaaaa atcatttccg attatcaaaa atccatcaag aaaactcgag aagaactagc
     9181 agataaaatc gagaacaaga cagctgcagt gttgtgggtg accaacaact cagcctttat
     9241 ggtcagcaaa aatcggtcaa gtggaagaat cgtatacgac gatctggaat ttggtgttcc
     9301 tgatctagtg gaagaggtct ccaaaaaagc cacttctgac tggtctgctg tttcctctga
     9361 aaagctagct gaattagatg ctgactacat catccttgtg aacagtgaca aagatgctgc
     9421 catgttcaat gaaccaagct ggaagaatct aaaagcagtg acagacaatc atgtactgca
     9481 attcggacct gaatctagtt ggctatataa cggacctatt gccagtcagg aaatggtcaa
     9541 tgatatcaaa gaaaaactaa attgatttta actaaaaaaa gcatcttcac gattagtcgt
     9601 gagatgcttt ttttcttatt aacaaactag acgcatagat tttattcttc ttttgaagca
     9661 accctatttt ttactctttc ccatttttga aaacgatggg catatagatt ttcttgatcc
     9721 gttatcccct catactcctc tataagggcg aagtctgaaa aatcaatatt cccaatatac
     9781 gtatcgcctt caaacgtgct atcgatcaat gttcgccaga tccgaccagt gtaaggaaga
     9841 agttcttgaa aaatccgact accacccgaa acatagatat cttctgagat cgtttgacta
     9901 tacgacaaaa gttcatcgat cgaatgcatt acttccgcat tttctttcgt gcgaaaattt
     9961 ggttgcgttg tcaacacgat gatatggcga taaggaagtg aaagatcccc cattccttca
    10021 taggtctttc ttcccatcac taaaattcga tccattgtat gttcgcgaaa gaaacgcata
    10081 tcatttggca atcgccatgg taacaaacca tttttgccga tcagaccatt tttatcttgt
    10141 gcccacatgg aaataaacat attatccgct ccttatgatt ttagatgttt tgagataaaa
    10201 aaagtctcaa ttctttgacc agcaaggaat tgagaacttt aaaaacatta ttttgtttca
    10261 cggtgcaaag taactttgcg ttcgcgtggg caatattttt gtttttccaa acgatcagga
    10321 ttgttacgtt tgtttttgct tgttagatag ttacgttctt tacaagaagt acactctaaa
    10381 gtgatgttta cgcgcatgtt tttccctccc atttttacaa gaatcctcta agatgactct
    10441 cagacttgat tatcttacca tgattttttc tagattgcta gtgtttttca cgattttgtt
    10501 aagtaaaact acttgacgat aaatacaacg gttttacttc tcaaacaaaa tctttttctt
    10561 tttgtataaa tacccttaca cttgtttata tagattatgt tttttaataa agggggatac
    10621 taatatgcca tggaacatga aggactttcc tgcatcaatg aaaaacttag ataaattgac
    10681 aagaaaaaaa gcaatcgaca tcgcaaatgc attattagat gaagggtacc ctgataaccg
    10741 tgcgatccca attgccattg atcaagcaaa aaaatggtat gaagatgcta gtgaatcaga
    10801 aaaacgaact ttcgaaaaag aaaaaaatcc aagcaagacg gatgaacacg atacgaatcc
    10861 tcgtgctgga aaactgcttg attcagatgt gatcgtagaa tatgaggaag aacaatggat
    10921 cgtgaaatct aaaggggcaa aaaaggcaag caaccatttt gatacaaaaa aagaagcaat
    10981 cgaaaaagga aagcaagtag cacaaaacaa agaatcaact ttgttcattt ataaaaaaga
    11041 tgggacaaaa gaaaaagaaa tcgattattg aacatatgta aaggggttgt gacgaaaatc
    11101 gtgtcacaac ccccttatgt tcgaaacaat ggtgttcctc tgccaactcc gaaccataag
    11161 tcataatatc tataaaacgg gaagagctgt tttttgaaat tgtttcttat cactcagtgt
    11221 taaacggtag gagaaaacct cttttttatt gatatttgat tttcatcaaa cagtcacata
    11281 gtcgattgct tctgcttgcg gaatcgtttc atctacaaag tagactttat accatgtcaa
    11341 gaaactgaag attgtccaga tttttctttg ctcttcttta cgtccttcgt gatggtcatc
    11401 tagcaacttc atgatttttt cttgatcaaa aaattctttt gcaaaatctg cttcgaataa
    11461 tgctttgact tgttcgtagc cgtgttcttc tttcaaccaa gctttgattg gcacagggaa
    11521 tcctaatttc acacgattcg accattcttc cggaagatgt ttgttcgcag cttgtctgaa
    11581 aatatctttt gtgttgtttt gattcaataa aaacttactt ggtatttgtt gagccaattt
    11641 catgacttcg atatccaata aaggtactcg gacttccaaa gaacttgcca tagaaagttt
    11701 atctgccttt aacaagatat cttttggcat ccattgatga agatcgacat attgcatctt
    11761 attgacttca tctttgattc cttctgtttt ctcgtaatga acagtcatga tttcatccac
    11821 agatggtgct gtttgatatt ttggtgttaa cacttctgat gcttctgatt cttcgaacac
    11881 tcgagcatga ccgataaaat attcttttgc aggagcaagt gattcatata aatggatccg
    11941 tccatggaag tttttcattt ttccgatttt acgtcctaaa ttatagcgtg ttccttttgg
    12001 taattttttc aatccttgag caatcacacg gatgaatttt gaattcgtat ggaatccata
    12061 cgtttggtat cccgcaaaca gttcatccgc cccttctcca gattggacta cccgcacact
    12121 ttgtgaagca agatttgcta aaaagtacaa aggtacgcaa gaaggatttg aatcaggttc
    12181 atctaagtga tactggatca aagggaatgc tttgaacgac atgtctccgt cgatcactgc
    12241 tgctgtatta tctaagtcca atagttcggt tagttttctg gcttcaatcg cttcattata
    12301 ggttttatca tcaaacccga ttgagaaaga atgatctggt ttcaatacag aggttacata
    12361 actggaatca accccgctgg ataagaaaga accaacttct acatcactga ccgtatgtgc
    12421 ttcaatagaa gcttgaacgg tttcgtcgat tttttcgatc cattcttgtc gggaatgcgt
    12481 ttcttttgtt tcaaaatctg catcccaata ttgctgaatg tctatttttc catctttata
    12541 cgtataataa tggccttcag gcaaacgata gacatctttg aagaatgttt cgccgtttaa
    12601 tggagaatat tggaaagtca tataaggttt caacgcttct ttgttcaatt ctttgttaaa
    12661 atcaggatga ggcagaaaac ttttgatttc tgaaccaaac ataaatgttc cgttcatttc
    12721 tgcataataa tatggtttga tcccaaagtg gtctcttgca ccgaataact cattcttttc
    12781 attatcccaa atagcaaaag caaacattcc gcggatcttt tgcaataatt ctgttcccca
    12841 ttcttcgtaa ccatgcaaaa ggacttctgt atctgcatgt gtttgaaaaa cgtggccagc
    12901 tgcaatcaat tcttctctca aaggctggta attatagatt tcgccattaa aaataatgat
    12961 ctttgtccga tcttcattgt aaataggctg agtaccgccc tctaagtcaa taatacttaa
    13021 tcttctgaat cctaaagcaa catgtttatc gatatattct cctgaactat taggtccacg
    13081 gtgaacgatt cgatccatca ttgtattaat aattgttttt ttgttgtcct tgtcgttaac
    13141 aaaacctaca ataccgcaca tttaactttc acatcctaat ataaaattac tgtttatttc
    13201 attcatatgc atcttatcat agaataaata gcggacgaat attttctctc ttacaatttc
    13261 gtcacgtgaa aacaaaagat gaaagtttct gtttttacag aaaataaagt cccaatatct
    13321 aatttaccat gttttctttt ttgaggctac cttattctct tcgtgttaaa aaaatattag
    13381 tggatgctat ttccaaaaaa accagcaaaa aaagacacga cctaaagatc gtgt
//
LOCUS       DARBDN010000070        13402 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000070 DARBDN010000000
VERSION     DARBDN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.070"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            291..2030
                     /gene="yfcC"
                     /locus_tag="SCH06_002014"
     CDS             291..2030
                     /gene="yfcC"
                     /locus_tag="SCH06_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEG1078564.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2187..3371
                     /gene="iadA"
                     /locus_tag="SCH06_002015"
     CDS             2187..3371
                     /gene="iadA"
                     /locus_tag="SCH06_002015"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HEG1078565.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3482..3685
                     /locus_tag="SCH06_002016"
     CDS             3482..3685
                     /locus_tag="SCH06_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEG1078566.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3786..4448)
                     /locus_tag="SCH06_002017"
     CDS             complement(3786..4448)
                     /locus_tag="SCH06_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078567.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4461..5963)
                     /locus_tag="SCH06_002018"
     CDS             complement(4461..5963)
                     /locus_tag="SCH06_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078568.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6511..8190
                     /locus_tag="SCH06_002019"
     CDS             6511..8190
                     /locus_tag="SCH06_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEG1078569.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8317..8796
                     /locus_tag="SCH06_002020"
     CDS             8317..8796
                     /locus_tag="SCH06_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEG1078570.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            9015..9695
                     /locus_tag="SCH06_002021"
     CDS             9015..9695
                     /locus_tag="SCH06_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HEG1078571.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9703..11034
                     /locus_tag="SCH06_002022"
     CDS             9703..11034
                     /locus_tag="SCH06_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEG1078572.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            11049..12011
                     /locus_tag="SCH06_002023"
     CDS             11049..12011
                     /locus_tag="SCH06_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEG1078573.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12122..12460
                     /locus_tag="SCH06_002024"
     CDS             12122..12460
                     /locus_tag="SCH06_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEG1078574.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12539..13246
                     /locus_tag="SCH06_002025"
     CDS             12539..13246
                     /locus_tag="SCH06_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HEG1078575.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4298 a         2348 c         2925 g         3831 t
ORIGIN      
        1 ttttgcaatg aaattcaatt tttcaatgat tgtaaaatga aaaaaacagg acgagatttt
       61 ctctaatcta aaaataaaaa aagaatttta aggaaaaaca gagaaataaa atacttaata
      121 taaatggaaa gagaaaaaaa taatcataca taggagaaaa aaaacaaaat agaaaaaagt
      181 gattttctaa taaattattc atgtggaaat gtcattttta ctgtataatt catttgatta
      241 tccatttttt attcatcaaa attactgaaa aaagaaagga agaaataaat ttgaagaaaa
      301 caaattcttc aggaaaaccg aaacgcgact tcactaaatt atcgacaccc catacgtatg
      361 tcattatttt tggtgtagtc atctttgcat ggatactgac ttttgtcgtt ccagcaggaa
      421 agttcagcac gcaagatatt gaatacaaag atgcaaatgg cgaaacaagt actcgtactg
      481 ttttacgtca agattccttc cgttatgctt acgagctgga taagtcgtat gtgtttgatc
      541 aattagaaga actgcaagat catccagcag aacgtgaaaa actggatgtt ccggaaaaag
      601 gattggaaaa agtcattgct gacggagaaa aaaatcttac gcaggaaaaa ctagatgaaa
      661 tctccttgac agatgatgtg ctttacgatc agtacggcga aaatatctat gatacttcta
      721 aaaaattgca taaaacagcc aaaatatggg gaacagatga ttttggcggc tttggtttct
      781 taaattttgt ttttgaagga ctagtatctg gagataagta tggatctgct gtagggatcg
      841 ctgcattgat ccttgttgtt ggaggtgctt ttggtattat tatgcgtacc ggagcgatcg
      901 acgcaggtat ctatgcgttt atcagtaaaa ctaagggact ggagcgttta gctttaccgc
      961 tattattctt tgctttttca ttcggtggcg ctacattcgg gatggcagaa gaggtaattc
     1021 cattctcaat ggtgatggtt ccatttgtca ttgcgttagg atatgactcg atcgtagcag
     1081 taaccgtgac ttatgtcgca tctcaagtcg gaaatgcgac ctcttggatg agcccgttta
     1141 gcgtagcggt ggctcaaggg attgctggaa tccccgtgtt gtctggtgcg acattccgat
     1201 tgattatgtg ggtagttgtt actgcattag ccgctggtta tatgatgata tatgcagaaa
     1261 aaatccgtaa aaaaccagaa agttcgttga cttacaaatc agatgattat ttccgttctc
     1321 atatcaaaaa gacatctgat gaaaataaaa aattcatgct tgggcataaa ttgatcttat
     1381 tagagatgtt agttgtcctt gtctggatcg tttggggcgt gactcaaaaa ggctattaca
     1441 ttccagaaat cgcttctcaa ttctttgtga tgggattagt tgctggaatc attgctgttc
     1501 ttttcaaatt agatggaatg aaagtcaatg acatcgcttc ttctttccaa tctggtgcag
     1561 ctgatttagc tggtacagca atcgtagtag gtatggccaa agggattctt cttgtcttgg
     1621 gaggatctga tgcatctgtt ccttcagctt tgaatacgat tttgcatggg atcgggacgg
     1681 cgttgaccgg tgttccagct gtcattggtg cttgggcgat gtacatcttc caaagtttgt
     1741 tcaacttggt tgttacatca aattcaggac aagcagcttt gactatgcca atcatggctc
     1801 cactggcaga tttagtaggt gtatccagac aagtagcagt tcttgcttat cagcttggtt
     1861 caggttttat ggacgctttt acacccgtat cagccagctt gattggtgtg ctaggtgttg
     1921 cacggatcga atgggcaaaa tgggcaagat tccaaatcaa gatgcaagga ttcctgtttg
     1981 ttttaggaac tattttcatc atgattgcca ttgcaatagg tctgcagtag tactggagac
     2041 ctgtaaataa aaaagtaatc caaacagtag ataaggactc caagaaccgt cattttacgg
     2101 taaaatcaaa ggagtaaaga tcctatcgtt tggattattt tttaagatcc tatcatcagt
     2161 tatacttaaa gaaagaggaa aaatgtatga aaatcattcg acaaattgaa gtgtttgcac
     2221 cagattactt aggaaaaatg gatgtactga ttgccggtgg gaagattttg gctgtagaag
     2281 aacagctaga aggcggctac gaaggagtgg aagtagaaga actttcaggt gagggaaaag
     2341 tactaacccc gggtttcatt gactgtcatt tccatatttt aggtggagga ggagaaggcg
     2401 gttatcaaaa tcgaacgcca gaagtcacat tgagccaatt gactacagct ggtgtaacga
     2461 cagttgtcgg ttgtttggga acagacggag aaggtagaga tatgactgcg ttgatcagca
     2521 aagcgaaagg tctggaagca gaaggaatct ccacttatgt atacgaaggt tcgtaccgat
     2581 tgccggtaaa aacagtaaca gattctatca tcaaagactt tttgacaatt gataaaatta
     2641 tcggaatcgg agaaatcgca gtatccgatc accgttcttc tcagccaagt tttgaagagt
     2701 tcgctcgtgc agtagcagat gctcgtgtag gaggcatgtt atccggaaaa gctgggatca
     2761 tcaatgtcca cttaggcgga ggaaaaagaa agctagagct attgacacga atcgtagaag
     2821 aaacagaaat tccgatcaca caatttttgc ctactcatgc aaatcgcaca ccagaattat
     2881 ttgaagcttg cgtggcattt gccaaacgtg gtggcacgat tgacttcact gctagcgaag
     2941 atcctgattt ttgggagaag acagatggtg aagttcgctt cagcaaagca ctgaaacgat
     3001 tgatcgagga agatgtttct ttagataatt tcacgatgac ctcagatgga caaggaagct
     3061 tgccttattt tgatgaaaac aatcatttcc tagggttagg agtaggaagt gccaaggcat
     3121 tgctagtagg gatcaaagaa gctgtgcaaa aagaaagtat ccctttggaa atcgccttac
     3181 gagctataac cagtaatcca gcacgtatat tgaaattgga taaaaaagga aaaatcgaaa
     3241 ttggtgctga tgcagatctg tgtatcttgg ataaagaaac gcttgatatt gatacagtta
     3301 tcgctaaagg agaaataatg gtccaagaaa aagaagtcaa agtatggggg actttcgaaa
     3361 aaagttttta atcaacagct ctaactatct tttttagaaa acgagcgttc tgtttgtctg
     3421 tatctgttgt tgatgttacc ctgaaggtag atcaataaac aaactaagag gaggaagcac
     3481 aatggcagat ttaaaaggac gttctaaaga tatgaaagat aaagtagtcg gtgaaggaaa
     3541 agaagcatac ggcaaagcaa cagacgacaa gagcaaagaa acagaaggga aagcacaatc
     3601 actaggtgct gacatcaaag aaaaagctcg aaatttaggc gacgaagtca aagacaagtt
     3661 ttctcgaaaa gacgaaaaaa aataaaaacc acttattact aattgaatca agcaaataaa
     3721 aaatccgaac catatctgcg agacagatat ggttcggatt ttttatttga tcattatcct
     3781 gttttttaaa cttcgatttt ttgaaatttt ttatttttta gttcaaagac ttcatcacag
     3841 ctttttgcta cttcaatctc atgagtcacg atgataatac agcgattttg ttcatgggcg
     3901 atttcttgga aaagtttgac gatatcttgt gaagttgttt catctagatt tccagtaggc
     3961 tcatccgcta cgattagttg atgttcacag cagatagcac gaacgatagc gactcgctgc
     4021 tgctgacctc ccgaaagttt ggtcacctgt ttttttgcta atatttcatc aattcctaca
     4081 cgagccagtc gatctaaagc aacttgtcga taattctctt gcttggtctt agtgatttcc
     4141 attgctgcta tgacgttgtc tagagccgat aaataaggaa gcaagttgta agcttggaaa
     4201 ataatcgaga catcattttt acgataactt cttaacccga ttttgttcag tgaacgatct
     4261 tgatagtata cctttccttc ttttggtgca tctagtccag aaataagcga aagaaaagtc
     4321 gtttttccag aaccacttgc tcctaaaata gcgtacattt ttccagcttc gaaattcagt
     4381 tctacatctt tataaagcgc atcttgcgga tcttgatacc aaaatcccaa ttgttctgtc
     4441 cgtaacatca aattcctcct ttagtttaat aggatttttc ttgggtttaa tcttaatatc
     4501 cctatagaag ctaaaaagac agaaaacaga ctgattccaa atgctactcc ggctaatagt
     4561 cccaattgtg caggtttgac attgatttcc aattcgctga cttgatcaga aacagcaaat
     4621 ggattattcg tggttccttg ttgaccatcg cgttgaccgc cttgttcttg tctgttacct
     4681 ggcatttgtc caccgccagg agcttgctgg ttttgtgtcg tggtttctgt ctgttggtca
     4741 agtagctgct gtcccacggc attcgcgacg acgtttccgc taagcgaagc aactcctaat
     4801 gcaagaatca tacaaatagc cacttcggta aacaattgga gaatgatttt acttctggat
     4861 tctcctaaag atagcaagac gcctaactca tgccgacgct cccgaatggt aatcataatg
     4921 atcagagtaa gtatgataat accggctaca gccactagta aaacaacatt tttagaaaaa
     4981 cttgccacgt tgtttaaagg ttccaacatt gactgataca tggaatcatt tgattgtaag
     5041 ctaaatgtat ctgtgtcgat cagcttctca gcttctttga gaaactcatc cattttatct
     5101 ggatcagata gagtgtaaat agcagaatct atcgtgttat cgtcagatgt cccatttagt
     5161 tcatttgcaa aagtgtaaga agtgtaaagt gtattcgacg gattcatgaa gttgaatttc
     5221 atacccatac tgccgcttgt ttcgctggat tcataaattc ctttgatcgt catttcataa
     5281 gtggtatctt catcttcagt actcgtgatt gtgaaagtat ctccgactgc caggtcattt
     5341 gtttctgcta gagtagaatc aatgactaca ttgtttgtgc ctttgtcgct gtcatctatt
     5401 ccttcaccat ccgtgatttt tgctgttcca tcagaaaaat tactattttg tgcagttgct
     5461 gacacaccac tgatttgaaa gtctgcttga gtcatttgcg gattcccgcc cattcctcca
     5521 gcaggttcac cgcctgcatc agtagtttct gaactgtctt cacttgaatc agaactagtg
     5581 atggcagtta ttccatcttt tgccatagct gaggcggaac tttcaaagga ataactcttt
     5641 acattatcta attcagctat tttttccgcg tccgttaagg aaactggtgt aagagaaaaa
     5701 ctgcctggat ctggacgttc ttcagtggta gaaccgcttg aagaagtttg ttcctgtttt
     5761 ttaaatgaag cttctcgatt ggcacttaaa gtcactgttg ctccaacttc tttttgtgct
     5821 tgattcgctg cttcttctgc agcgcttcga atcgtgaggc cagctagcac aaaaataaga
     5881 atggctgtga acacggcaaa caataacaat gaacgtcccc attttacttt tgtacttttc
     5941 catgcacgtt tcataaaatt catattttgc atccctccta gtagatgcat ttgataatag
     6001 acaacctatc ttaaagctag cttaaatctt atgctgtttg cacaccatca acatgaggtt
     6061 ctgtatatat aaaaagtcac tatagttatt gcaaaaaatg tggtaaaatg aaaaaagtat
     6121 gtttcaaacc gacgaagaag aaatgaaaga ggaatagcaa aagaaatcct agatgctaca
     6181 gagggatttt tacgtgcata gttgttctaa caattgctga tactagcgat ttagtttatt
     6241 tgttgtataa taatggggaa cagctgaata cttatataag tattctggct atagcgtttc
     6301 gcaaaagatc cattttgtta atgaagtata tccaaaataa aatgcccatc caactgtcag
     6361 aacgcggatg tgctggtaat tttcctgctg attctccata agttgagaaa tagtgatttt
     6421 gcatatgctt cattggaatg gctcatatat ttagataaag aagaaaatcg acatctttaa
     6481 acttggatgt cataagaaga ggtgaagttt gtgagtacca ttaaaattat cccattaggc
     6541 ggcgttcgtg aaaatggaaa aaacatgtat gtcgcagaag tgggcgagga tatttttatt
     6601 ttagattgtg ggctaaaata tcctgaaaat gagttgttgg ggatcgacgt cgtaatccct
     6661 gattttacgt atttagaaga aaacattgat cgtgtagctg gtgtcttttt aacacatgga
     6721 catgcagatg cgatcggggc acttccttac ttgttgtcaa aaatttctgt accagtattc
     6781 gggacagagt tgacgatcga gttagcaaaa ttgaatgtca gtcgtaatga agcagccaaa
     6841 ggatttaagg atttccatgt ggtagatgag catacagaaa tagactttgg tgaaacagta
     6901 gtgagctttt tccgtaccac tcatacgata ccagattcag tggggatcaa tctgaaaaca
     6961 aaagaaggta gtatcgttta tacgggagat tttaaatttg accaaacggc tatcccaatg
     7021 tatcaaacag attatgcacg attggcggaa atcggcaaag aaggagtctt agccttacta
     7081 agtgaatcgg caaatgcaga aaatcctcag cctgtagctt ctgaagccca aatagcagat
     7141 gaagtatttg atacgatcaa atattgggaa gggcgtatca tcgtcgcttg tgtagcaagt
     7201 aatttgcaac gagtgcaaca agtattggat gcagcagaaa aagcacaacg aaaagttgtc
     7261 ttgactggtc aagatttcga acgaattatt cgcacagcga tgcgtttaga aaaacttcaa
     7321 ttaccaagtg aagatctgct tgttacgttg aaagacatga aaaactatga tccagaagaa
     7381 ctgatcattt tagaaactgg ccgaatgggt gaacccatca agtctctgca aaaaatggca
     7441 aacggtacac accgtaatgt caagattgaa gaaggagatt tggtttatat cactactacg
     7501 ccaagcatcg cgatggaaac catcgtggcg aaaacggaag atatcattta tcgagctggt
     7561 ggaacagtga agttgatctc tgagaatatg cgcgtttctg gccatgccaa tcctaatgac
     7621 ttgcaattaa tgatcaattt gatgaaacca acatattttg tgccagttca aggagagtat
     7681 cgtgaattag ctgctcatgc agatttggct catgcagtag ggatgccata caaaaatatc
     7741 tatattactg gacgcggaga cgtgctggaa tataagaaca agcgtatgag tgttgcagga
     7801 actacaagtg cagaaaatgt aatgattgat ggattaggca taggtgatat cggaaacatt
     7861 gttttacgtg atcgaaaaat cttgtcagaa gacgggattt tcgtagcggt tgtcactatc
     7921 agtcggcgag aaaagaaaat catttcaaaa cctcaaatta cttcacgggg attcgtttac
     7981 gtaaaagcta gccgtgatct gatgaaagaa agcagcaata tgattgaaac aatcgttgag
     8041 aaacatttag aaagcaatga ttttgagtgg agcaaattaa agcaagacat ccgagatcaa
     8101 ttaggccgtt acttatttga acaaacaaaa cgccgcccag tgatcttgcc agtcattatg
     8161 gaagctactc aacgtcgaaa taaaaaataa acaaaaagag taagatgaac ctctctatag
     8221 agtgctcgtc ttgctctttt tttgcgaaaa acaaataatt tttgaataca gcatccctcg
     8281 ctttataata aacgatagaa taaagggagt gaatcaatga tgagtcaaac aaaagtcgaa
     8341 cgttatttag aagaacaaaa gatcagctat caaccacttg attttagtca tgtggtagaa
     8401 gaatctttca cagaagaact acaaaaaaga gggattgatc cagctttgat atgtaaaact
     8461 ctcgtagtga aaggaaacaa aactggggtg atcatcgcat tgattccttt gaacgatcac
     8521 ttagattaca aaaaaacgag acaagtgacg aaagatcgta aagttggttt tcctggaatg
     8581 gattttgtat taatgcatac aggatatccc cacggagcaa acacccctat tggaataaaa
     8641 ctcgcacatc ctgattattg ttttttagca gacagttctt taaaagaaaa agaagaagta
     8701 attgtgtcaa gcggtgaaat cgggagaagc cttcggataa aagtagccga tttagaaaag
     8761 atcgtccatc ctatttacgc tgatttaatt agttaaggga cgagaagaga agctaagcag
     8821 agcagagacc tcaaacttga gattatatct gcttggtact tggtgcatcc tgtattatct
     8881 gttacaattg ctttgtacat actgtactat caatccaatg aaaatatatt tagcagctat
     8941 attttttcat tgatgtgcaa gtgatgaaat cgtttttaat aaaaaagata cagagaaaac
     9001 gcgaggtgta aaatatgaaa attacgtatc atggacattc ctgtttaaca attgaaatgg
     9061 aaaatggcca acgcgtgatg attgacccgt ttattacagg aaatccattg acagacttaa
     9121 ctgcagaaga agtaaagaca gattggttgc tgattactca tggtcatagt gaccacatag
     9181 gagatatgat tcctattgca aaagaaaatc aagccacaat tatcagtatt gttgagattg
     9241 ctgattatgc gaacagcaga ggagtagatt cattcggtat gaatatcggt ggaaaacatg
     9301 cgtttccatt cggcgtggta aaattcgtac atgcacagca tagttcaagc tatgaagtag
     9361 acggtatcgt tcagtatatg ggcgagccta gcggaattat tattcaagca gaaggaaaaa
     9421 cgatttatca tgcaggggat actgcttatt tcagtgatct aggattgctt gcagaagaat
     9481 tcgatattga tgtcgctttc ttgccgattg gcgataacta tacgatgggg ccagaagatg
     9541 cagcaaaggc tgcgcaaaca attcgtgcca agaaagtagt tccaatccat tacaatactt
     9601 tccctgtcat tgaacaagat cccgaatctt ttgtagagtt actggaagat agtgaaggaa
     9661 aaataatgag cgtctcggaa acgctggaag tgtaggcaga aaatggcgac aaaacatgat
     9721 ttgattttag aatatattga aagtttacct gttggcaatc gaatttctgt aagaagcatc
     9781 gcaaaagaat tgaatgtcag tgaaggaaca gcgtaccgtg caatcaaaga tgcagaaaat
     9841 gtcggactag tttcaacaat tcaacgagta gggaccatcc gtatcgaacg caaattaaaa
     9901 aaacatattg aacgtttgac atttggcgag gtcgtcagga tcattgaagg ggacgtttta
     9961 ggcggggcgg caggattaga caaggtcttg aataaattcg tcatcggcgc gatgactaaa
    10021 catgccatgg aacgctatat tacgccagga tcactaatga tcgtcggcaa ccgggcggaa
    10081 gtccaaaaat tagcattgga agatggcgcc gcagtattga tcacaggagg attcaatacg
    10141 actgctgaga ttgcaaagct agctgatgat cttgaaatgc cgatcttacg cacctcttat
    10201 gatacattta cagtcgcaac catgatcaac cgagcgttaa gcgaccaatt gatcaaaaaa
    10261 gatatcatgc ttgtcagtga tatctatatg ccagctgaaa agactcatta tttgcagcag
    10321 acagatacga tttctgatta tcagcgtttg tcagaagaaa cgcagcattc gcgttttcca
    10381 gtcgtcaacc gccatcatcg tttgatgggg attgttacgg caaaagatgt tttagggaaa
    10441 tcgccaaacc agatcatcga tcgggtgatg acgaaagaac caatcagtgt aaagaaaaca
    10501 atgagtattg cctctgttag ccatcaaatg atctgggatg ggctagaagt catgccggtc
    10561 gtttccgatg acttgacatt ggaaggcttg attacccggc aagatgtaat gaaagcgatg
    10621 cagcttgtcc agcgacaacc gcagattgca gatacgattt cggatcagat atctggaaat
    10681 atccatacga ttgatactga ccgtgaagga aatcgtttgg aaaaccctaa gttcaaattc
    10741 gtagtagcac cacaaatggt caatggcgtt ggaaccattt cttttggcgt acttagcgaa
    10801 atcatttctg atgtcgcaca aaaaacaatg gtgatgaacc aaaaacgaaa tatcttgatt
    10861 gaacaagtga acctacatta tttgcggctg atccaattgg aaagcgaatt agacattcgt
    10921 ccacgtgtat tggaaatcgg cagacgttcc gctaaactgg atatcgaagt gtttattgaa
    10981 aacaccatcg tttccaaagc aatcgttgtt tgtcaagtaa tggaacgttc ttagaaagca
    11041 ggagtgaaat gacagtacag caagaaatag tagatacaat aaaaaaatac gataaaatca
    11101 ttatccacag gcatttgcgc cctgatcctg atgcattagg atcacaagta ggattagccg
    11161 aactattacg ggaaagtttc ccagaaaaag aaatacgtca agtaggtgaa acgattgaag
    11221 ggcttcgctt tttagcagaa atgcaagaag ttgaagatgt cttctaccaa ggagcgctag
    11281 tcatcgtgac tgatacagct aattcaccca gaatcagtga tcaaagatat cagttggcag
    11341 aaaaactgat caaaatcgac catcatccca atgatgaccc ttatggagat cttgtgtggg
    11401 taaatacaaa agcaagtagc tgtagtgaga tgattgcaga atttgctttg atgtttcctg
    11461 aatctttaaa gatgaacgtt aaggctgcac ggttacttta tgcaggaatc gtcggagata
    11521 cagggcgctt tttgtatccc tccacgacgt cccgtacatt agagattgct tcgatattga
    11581 gaaattatcc atttgatgca agtgctttga acagagagat tgaacaaatg ccgatgaaag
    11641 tcgctaaact ttccggttat ctttatcaaa atatccaggt ggatgaaaat ggtgcaggaa
    11701 gaataatcct tccgcaagaa attcttgata aatatggaat cgatgattca gagacagctt
    11761 cgatcgtttc acttcctgga gtgattgacg aagtgctggc ttgggggatt tttgttcagc
    11821 agccttcagg gtattaccgc gtacgtttac gttctaaggg gccgatcatc aatgaattgg
    11881 ctaaacgcca tcatggagga ggccatccat tagcaagtgg tgcgaatgca aaagatttag
    11941 cagaagtaga ggaaatctat aaagagatcc aagatatatg ccaatcgtat aagagcagaa
    12001 aaacagaatg atacttcgtt cgaaaacgtg ccttttgtag taaaaatcac aaatgtatct
    12061 tttcaagatc ttctttttcc gttacaatag tgctcactaa agattttaaa ggagaaagaa
    12121 gatgacatta ccaaattgcc cagaatgtgg ctcagagtac acatatgaag atcgaggctt
    12181 gttgatttgc ccagaatgcg ggaacgaatg gaacaaagaa gaacaagaaa ctgtcataga
    12241 agacggatta gtggtattag atgcaaatgg aaaccgtctg ttagagggcg atagcgtgac
    12301 agtgattaaa gacttgaaag taaaaggtgc gtcaggtgcc attaaacaag gaacaaaagt
    12361 caagaacatc cgtttagtag aaggcgatca taatatcgat tgcaaggtag aaggatttgg
    12421 accgatgaaa ctgaaatcgg aatttgtgaa aaagaattaa agaatattca aggtcttttc
    12481 acattctttt cctactacta atgataaaat aaagtaaacg aaaaggagtg aaacgaaaat
    12541 gtatggttat ggaatgtatg gttttttaga tccgacattt cttttggtca ttcttggatt
    12601 agttatttcc ggaattgcgt cagcgtacgt caatagtact ttccgaaaat acgatcaagt
    12661 gagaagcaaa aacaatgtga ctggtacaca agcagcacaa tatatattac aaagtcaaca
    12721 gataaataat gtcggtgttc aacaaattgc cggagatctc acagataact acaattcagg
    12781 taataagatg ttgagtttgt ctcaagcaac tgcacagtct acttcagttg ctgcgatagg
    12841 tgtagcagct catgaatgcg gacatgcggt acaagatgct tcgggttatg tcccattgaa
    12901 gattcgtgca gcacttgttc cagcagctaa ctttggttcg atgatttcgt tccccttgat
    12961 tatggtaggt gtattgctta gctggaactc tacgttaatc aatatcggga ttttcgcttt
    13021 ttctttagca ttacttttcc aattggtgac attaccagtc gaatttaacg cgtctcggcg
    13081 agcaatccaa attttgagtg aaggcggact actgacggaa gaagaagtac cgatggcaag
    13141 acacgtatta tttgcagcag cactgactta tgttgcagca gcgctttcga cattcctgca
    13201 gctgttgcgc ttgatcttat tgttcggcgg caaccgaaga gattaaaata aagaagttgt
    13261 gaaatcagcg ctttgatctg agctaatacc gagagttagc tgattgaata ccatttattt
    13321 ggaataaggg ctctttgtca ataaggactg atgggttgta caaaatcaaa tctgggtcag
    13381 aatgaacctc attctggctc ag
//
LOCUS       DARBDN010000071        13399 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000071 DARBDN010000000
VERSION     DARBDN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.071"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(15..707)
                     /locus_tag="SCH06_002026"
     CDS             complement(15..707)
                     /locus_tag="SCH06_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEG1078576.1"
                     /translation="MQIELQHTHDKETFEKNYKVYFELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1144..1713)
                     /locus_tag="SCH06_002027"
     CDS             complement(1144..1713)
                     /locus_tag="SCH06_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEG1078577.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1787..2110)
                     /locus_tag="SCH06_002028"
     CDS             complement(1787..2110)
                     /locus_tag="SCH06_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078578.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2264..3076)
                     /locus_tag="SCH06_002029"
     CDS             complement(2264..3076)
                     /locus_tag="SCH06_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078579.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3430..4278
                     /locus_tag="SCH06_002030"
     CDS             3430..4278
                     /locus_tag="SCH06_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HEG1078580.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4423..5364
                     /locus_tag="SCH06_002031"
     CDS             4423..5364
                     /locus_tag="SCH06_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HEG1078581.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGLPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5354..7525
                     /locus_tag="SCH06_002032"
                     /pseudo
     CDS             5354..7525
                     /locus_tag="SCH06_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7637..9808)
                     /gene="copB"
                     /locus_tag="SCH06_002033"
     CDS             complement(7637..9808)
                     /gene="copB"
                     /locus_tag="SCH06_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HEG1078582.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9828..12014)
                     /locus_tag="SCH06_002034"
     CDS             complement(9828..12014)
                     /locus_tag="SCH06_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEG1078583.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12014..12223)
                     /gene="copZ"
                     /locus_tag="SCH06_002035"
     CDS             complement(12014..12223)
                     /gene="copZ"
                     /locus_tag="SCH06_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HEG1078584.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12236..12676)
                     /locus_tag="SCH06_002036"
     CDS             complement(12236..12676)
                     /locus_tag="SCH06_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEG1078585.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12750..13289)
                     /locus_tag="SCH06_002037"
     CDS             complement(12750..13289)
                     /locus_tag="SCH06_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEG1078586.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3765 a         2807 c         2381 g         4446 t
ORIGIN      
        1 gaggggggga ttttttatcg ttgtggaata tttaaatacc aacgcttgtc atgaaaatct
       61 tgtgctccac ccttagtatt tccttctgga tcgtttgtcg cacgcatcat gacgtatact
      121 ttcttattag ggaaatcacg catattgaaa gatacatgat agccaacatt tcctaaagta
      181 ttataagctt gatttacgtc tggtctataa atcccatcag ctcttactct agctagttct
      241 tttccagtat tgtagtccat aatgaaaata tactcgtatt tataattagc aatgtgccat
      301 ccagctacat gcaagtttgc gttttcgatt tctccgaact gatcaatgtg ggcgtaattt
      361 gttccatctg tcagcgtaga atttgcagca cctgctcgag ttggatcaat tactggttta
      421 tcctccgaag tagttggatt atcatccgta aaaccatgag ccaaatcata ggctagtttt
      481 tctttactta cacccatttc agaaagataa ccgtaaggat ctgtatgatc gccccaaata
      541 ttttgtgtta cccataaatg cgatttgatt cctggttggt tataaggagt gtctaatgtt
      601 aatggaatac catatttcat tgctgaatct cttgccaatt caaagtatac tttatagttc
      661 ttttcaaaag tttctttatc atgtgtatgt tgtaactcga tttgcacagg acttttggct
      721 cacgaggttg tcctactcta catcttgctg atagatatgc tgaaaggaaa acaccaacat
      781 tatgttttgc tttttcagct agaacgagac aagcaggaat acctttagaa gatatcaaag
      841 gttttttagg tcataaagat gtttccacta cacaagtcta tgcccatatt tctcccgaag
      901 tgaaaaaaag atcaatgaat caactagaaa actatataga agagcaaata aaaaagcact
      961 caaattgagt gcttttttaa gctcactatc actaaaacta tcactaattt tatttataag
     1021 cgaacatgtt tctatcactg attttttaaa tctagcgaaa aacccttatc ttaaaggcgt
     1081 tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc ctagaagtgc gaacatggtt
     1141 ttcttatagc tcatgtagaa aaattttctt gatgatgatt ttatccatca attgagattg
     1201 actgttttgc tctcctatga tttcagctat gattgtccga ttttgcggtt ttcttcttaa
     1261 ctggtagttg attttcccag tttccatcaa ctcgctaagc atatccacga ctccgccaaa
     1321 tccggtcttt ttcgtaataa aacctagtgc taccattcgt tcatctagat tttttgctgt
     1381 aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg gccagctctt ccatcccttc
     1441 agcattggat acgacggaag ctgttttgtt aataggttct tcgtttattt cttttggttc
     1501 tttcctctcc actttcactg tttgacgaag gacatctagt tcttgcaaga gcgtttcgta
     1561 ttgttcttgg gtcagcatca cgccagctac tttttcacga ttaaatatat atacgccagt
     1621 tcccgcgtct cgcgcttgag caaatacatc catcggcgat cgtttcactt ctgtgatcga
     1681 agatgtggga acttctaatt tctttaattc caatggattt cctcctttac taatcgcttt
     1741 ttattatagc acagactgac ttgttttgat cttttttcca aaggttttat cggtttttgc
     1801 ctaaccagta attgatatcg gtaagaagtc tttcgatacc aaatgaagga tggtacagat
     1861 acgttttttg atcttcgtta tggtctagtg gaaaaaaatg atcgatgatc actagatctg
     1921 cataccgagg cggcttattt cgagtacata catgtataga gatccgtttt cgatgtctta
     1981 gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg gtgttcatag cgaaaaaaaa
     2041 agacgatttt cacttcagga gggtggacat ctaaataccc tcgttcctgg agtgttttca
     2101 gtaaaagcat cccccactct actgcggggt gtgcaagtgc ttgttggatc gctagccgaa
     2161 attgatatag tttatctttg gaattgggaa atttttctaa tgtttcctga taataacgaa
     2221 cttcttctat cagccggtca tggataccaa ttacgtaacg aagtcattct tggtaaagta
     2281 cttttgtcag ctttgatttg ctttcgctct caaattcgct attcagccaa aacagcgaat
     2341 caagcttttc agtcacaatc gtcaatttcc gatagtcttg tgtctcttct atccgtttcc
     2401 accgcttttc agtaatctgg ttacagctca agcgcaaaat tgctagataa tttttttctt
     2461 ttattggcaa aatctgctcc tctctaaata gcaattcagg aaacaattca aagaatagtg
     2521 ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt tctttgcttc aataattgga
     2581 tgaacatctc agaaaaggac tgctctccat catctgcaaa aaaatgcgga aaatctttca
     2641 aaaagcaaaa cagcagatat cttacttttc tttctgaacc aaagatctgt gcttttttat
     2701 aagaaaaaga aaggtggtac tcgccaaacc actttctcaa tcgctcttgc gtagaacgat
     2761 cgtacttctg ctcgtaaggt tcattcaata gcagattttt cagtaaacaa aacgggggtg
     2821 attggatcag aaaaacaaac aagagataag gttcgctata tccttgatca taaactaact
     2881 gaacggtttt cttatgaaga atcagctgaa tgggacagtc gctttccgcc aaacgtttca
     2941 gatgccgatc cactgtttta acatcgattt tcagttcttc agctaaatca gcttttcgcc
     3001 agatcaaatc tttcattaga ttgattagtg aaaataaatt ctgtgcattt tttgataata
     3061 gtttttgcca tctcatcgat catttctcac ctgatttcta aacatattgt ttgatcaaaa
     3121 tgggttcact cctaaaaaga taaaaaactc cctttctatt tatttaaata cgcaaatctt
     3181 cctcattatt ttttatttta ctcaatttaa tcgtattctc atttcaaaac gaatgtactt
     3241 taaaaaaaca taataagatc actttgcttg tatgatgtat tcccttccat tacaatgaaa
     3301 taaatagcga ttttatgaga aggtgatgtg aaaatggaag aaaaaataga agaatccaaa
     3361 caaaaaatcg atcagttgat ataagaatta gaaaaagcgg tcatcagcaa acgttcaact
     3421 atccaattga tgatcgtggc cctattagca ggtggtcatg tcttattcga agatattccc
     3481 ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag ctgtacaggg aaccttcagc
     3541 agagtccaat gtactcctga tctgctgcct agtgatattc ttggtttttc cgtatacaat
     3601 tcacaatcaa aagagtttga atttcgtccg ggaccgatct ttaccacgat cttgttagca
     3661 gatgagatca atcgtacgac tcctcgtact cagtcagcac ttttagaagc aatggccgag
     3721 aatcatgcaa cgatcgacaa caatacatac cctctagaca atcatttttt tgtcttagct
     3781 acgcaaaatc caatcgagta cgaaggaaca tatcctttgc cggaagcaca gctcgatcgt
     3841 tttttattcc gactacaaat cggttatcct tcttttgatg acgaactttt gctacttttg
     3901 gataaattcg aaaaagtgtt ggataactta aatgaagtat tgaacagtta tgaaatagaa
     3961 gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg aagtggcatc ttatgccttg
     4021 cagttagtgt cagcaacaag aagtcatgct gccatccagc ttggcatcag tccacgagga
     4081 agcctttcct ttattcaggc agcaaaagct tatgctttaa tccatgggag aaattacgtc
     4141 acgcccaaag atttgcagga tttagttcct tacgtgtttt cccatcgcct gattttttac
     4201 gatcgttcat tgaaggaaga cgaaaagaaa caaatcattc atactcttgt tgcacaaatt
     4261 cctattcctg tgaggtagat tgaggtagac aatggaaaaa atcaaagatt atttcattaa
     4321 ttttgtgtta tttctggtat atttcatcat tgtgcttttt gctcttgtat tcaacaattc
     4381 tttaggctgg ttcttgttgg ccttttttac tctttatgta tcatggagct tgatttcatt
     4441 aagcagcttt ctaaagaaac tttcggttac ttgtacattg cagccactcg tttatcgcaa
     4501 aaaaagtatg caggttattt tttccatagc aaaaaagaga actttttctt tacctctccc
     4561 tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa aacaagagat tttgattctt
     4621 acaaataaac cgcaagaagt ccaattgctt tggcagccaa aagaaagagg atgccatgaa
     4681 acattaactg tcatttttac agcctatgat agtctaggac ttttcagaaa aagtgcaaaa
     4741 agagagatct cttttcctgt gactgttctg cctgcttttt gtaagattca agcagaaaaa
     4801 ttacagagag ttctggaaaa aaaacagcag ctgaacgcgt accaaagagg tcttgatttt
     4861 cgggaacatc gcgcttatcg tccaggtgat tctttcaacc gaatcgattg gaaattgtct
     4921 gctcatactc aagagtggtt ataccgtgaa tacgattatc aagaagaaga atgttctcct
     4981 cttttttgct tttggggttt gcccagtcca aaatttgaac ctctgctaga cttgtatttt
     5041 tctttatggc atttgagaaa agaaaagcag ccggaacttc tgatattagg caaccgcgcc
     5101 tttcatggca aagaccccgg tcatacctat tttgcttctt tggaagctgg cgatgagaaa
     5161 gcttttttcg cacacttgaa aaaatatgca aaaaaacaaa tcgtcctctt tgttcctgag
     5221 aattctcctg aagtctcaga agctattgaa acattgtcaa aagatcgaac ggtttatctt
     5281 gtttatttcg tagaaaaaca actcatggtc caagaaaaag acaagatatg ttcattgcca
     5341 ggaggtgaat ggattgacga ttaaacggga aaaatggctg cgtggcgttt actcctttgt
     5401 gatactaagt gtaggtgctc cgatatttgt agtagctaat caattgcaaa acagctacct
     5461 tcttatccta actattggtg tcctatgcct tattgtctgc tgtattccta aaaaatgggt
     5521 acgtttgctg ctttctttgc cagtaatgat aggttgtttg tttttatatt ttccttcgaa
     5581 gacattttcc atattatgga tcttacagtt tttttcgtca gtcacagagg aattcttcca
     5641 tctatcccaa ggtaaacttt attatttgcc agaaaagaca gctttttttc tcataatgtt
     5701 gctgatctat ttatttatta cattgaccgt ggattacgac tattggtacg caccctttct
     5761 ttctttgatg gcttacttca tgatgcttac cgtttttcgg aaaaaagatt tactgtacga
     5821 aatgattgcg gtagtaactg ttttgttcgt gtatctggca gcaaggcaat ttttctccat
     5881 ccggttgttg tcgggaaaca ctcgattcca gtcattgact acagttctgc ttatttgttt
     5941 cttaactttt agcgctatct tgcctttata tcttccgaaa gtacaccaat ctctcgagga
     6001 aacgagtgaa ccgatccgag aatatcttaa tgatgaaggg ctttatgaca cactccatga
     6061 gtatcaatta accggaagtg caagaacagg cttcagtgag aatgatgaac agcttggtgg
     6121 acctttatat gataatggcg aagttgtttt tacagcgaac caaaaaggaa atggctattg
     6181 gaagatcgaa aataaaaatc attacaccgg ttctggatgg atagaagatc aggacgcacc
     6241 catccaacca atccaagaat tccctgttga catcacgagc taccaaaccg ttatagaaga
     6301 caaagaaaac attacattga ccctaaaaaa acaagttttc ttaccttatc cttatggaaa
     6361 tactaccttg actgattttt cattagctag tggacaaacg ctttactatt tgcctgaaag
     6421 ccagcgattc attcctgtcc cgaatgaatc gacacgttct gcaactttac aaacagaaag
     6481 gttagttttt acgagagaag aattaaaaag cagtcagtta aaagctgatg atttagaaaa
     6541 tcagcagaca aatcttcaat tgccaaaaag tttgcctaaa cgtattgagg acttggcggt
     6601 cgaattgacc aaaaatgaag caactttaat tcgtaaagtc gaagctgtct aacagtattt
     6661 aaaaacaagc ggaaatttcc gctattccaa aacggatacc gggcatactc caaaagaaca
     6721 cgattatgtg gattatttcc tctttgattc aaaagtcggc tattgtgaca acttttcaac
     6781 ttctatggtc gtccttcttc gaacacttgg tatcccagct cgctggacaa aaggttttac
     6841 aaatgggctc agaacaggca cagataatca agggaatgag gaatacagca ttctcaatag
     6901 tcatgctcat tcttggccag aggtatactt tcctggattt ggctggcttc catttgaacc
     6961 aaccccttca tttgccaatc caatgggttc acaaccagtt gctgaaacaa ccgaaaccgt
     7021 ccagcctgct atcgaacaac caaatgaaag cgaaaatatg gcagaaacta tttccagtga
     7081 gagatctgag gtcattccat cagaagaaac aacactcaca ccagcttata aaatcgtctt
     7141 attcagcctt ggagtgtgtt tatccgtctt gttgttcttt ctattgttat tcagaaaatc
     7201 tctgcgctgg acaagttatc ttatctatct tcattttttt gcttctacta atacgattgc
     7261 atatcaaaaa cttcttaacc ctttggaaac attggtaccg cgcaaacccg cagaatcttt
     7321 gcaggaatat agcctgcgaa tagaacaaga attcaagcta gatctgcgtt tcattcgatt
     7381 aactactcaa tatgaagcag aaatatatgg acgacaagca gatccggtaa aattcgataa
     7441 aaaaacctat ttagaaataa cgcatataat aagaaaaatg gtatacaaaa aaattctgac
     7501 aaaagggagc cgcttcaaaa aataagataa aatttctgga gaatctactt ctggaatgcc
     7561 gagaaccagc tgattgagta tcgattactc gaaaaaaagg ttgtgacacg ttttttgtca
     7621 caaccttttt tcattattat ctgattttca atgtcaaagc atttagagct acaactaccg
     7681 tacttaacga catcaagaca gcaccaactg ctggacttaa tatgatacca attggcgcaa
     7741 gaattccggc tgctagcgga attgcaagaa tattgtaacc tgccccccac cagaggttct
     7801 ggatcatttt ctttcgcgtt tgcttggcta gatcaagaaa atgcaaaata tcttttggat
     7861 cgctgtttgt caatacgaca tccgcagaat cgattgcgat atctgtccct gcaccgattg
     7921 ccatcccgat tgaagcacgg gctaaacttg gcgcatcatt gatcccatca cccaccatga
     7981 ttactttttt cccttggtca aggtatttct ggacaacagc ttctttatca tctggtaata
     8041 aaccgccata atattcttcg atccctaaat aatctgctac tgcttgggca gcgtttttat
     8101 tgtcaccagt aagcatgaca ggagtgattt ttctttcttt caatgttcgg ataaattctt
     8161 ttgcttctgt ttttactacg tcacctaaag caacgattgc agctagatga ttttctaaaa
     8221 tcaggaagct gatggtattt ccttgttctt ggtaaggttt caataatgct tgttctacgt
     8281 ttaatccgag acgctcaact tctttttcat taactatttt cacttgttgt tttttgactg
     8341 ttgcctctag cccgactcct gaaagatttt ttagattttc agcttgataa ggcttgattt
     8401 catgttcttt caaataattc ataatgccaa cagccaatgg atgattggca ttcgcttcca
     8461 aggctcctag atattgaagg atttcatttt tattgaacgc atcatcaagt acttcgacac
     8521 ccgttacagt aaattttcct tctgttagtg ttcctgtttt gtccagcatg atcacatcta
     8581 gatcattggc ttgctccagt gcattgcggt ttttcaaaag taatccgttt ttagctgcta
     8641 ttgatgtgga acgagcaaca actaatggga tagctaaacc tagagcatga ggacaggcga
     8701 tgataaagac tgttaccata cgttctaatg cattaggaag atctgtcaag aacaaccagg
     8761 cgatgaatgc caggataccc acaattaatg cgacataaaa cagccatttt gccactttgt
     8821 cagataatga ctctagcttg gatttttctc cttgtgcttt tcgcaccatt tccataacct
     8881 tcgctagata accattttca ccagttccag ttacttcgat ttcgatcgtt ccatccccat
     8941 tgatagaacc gccaatcact ttgtcattgg cttgtttttt gattcctctt gattcgccag
     9001 tcacagctga ttcgtcaaca attgtttcac ctttcaagat tacaccatct gttggcattt
     9061 tatcaccaga ccggacgatc aaacgatcac cttcgtttac ttctttcaat gaaactgtct
     9121 cttcttttcc atctttcgtc aagcgtttca ctgattctgg cagtaattct gctagttttt
     9181 gtaaagcatt gctggcattc gacacagcat tcatttcaat ccagtgacct agtagcataa
     9241 taacgatcaa agtagccaat tcccagaaga aatccatgac gtgtgtatgt ggattgagca
     9301 gatttgcgat aaacgaatag acactataaa tatatgcaac tgtaatcccc atcgcgatca
     9361 gtgtcatcat agcaggactt ttttgtttca attccatctt agctccactt aaaaatggct
     9421 gaccgccata gataaatagt atagttgcta agatcaatac gagccaatca gaaccaggaa
     9481 acgttacttg aaatggaaat tccattccca tcattggtga aaaaagaatg attgggatag
     9541 ctaggataag cgatagccaa aatttttgtt tgaaattccc catgtgcatg gaatgatcca
     9601 tgccgccgtg ttcgtgatcc atgtgcatcg aatggtccat ttgtttgctg tttgctatat
     9661 ctccatggtt atgtcccatg tgcatggaat gatccatctg actatggtca tgtttcatct
     9721 ccatctgttt ttcatgagat tctgtacttt ctttgtttac tacttctttt ttatgctcat
     9781 gttttttctc catatcgttc ccattcattt ttactccatc ccttctctta ctttttcatg
     9841 tgtcgattta agcacaggga gttcaacaat acactgacgg aactaaacgc catcgctcct
     9901 cctgcaatga ttggattcaa aaagcctagt gcggcaaaag gaataccaat cgtattatag
     9961 acaaaagccc agaaaagatt ttgtttgatt tttctcaatg tcaacctaga caactcgatt
    10021 gtttgtgcaa tggatgccaa actgctattc atcagcgtca catcggctgt ttccatcgca
    10081 atgtccgttc cacttcccat tgccataccg acatcagcta atgctaaggc cggtgcatca
    10141 ttgattccat cgcctgccat accgactttt ttgccatctt tctgaagttt ttctacgtag
    10201 gctgctttat cctctggaag tacttcagca aagatatgct ttggatcaat accaacttgt
    10261 ttaccaatcg tttcggctgc cagtttgttg tctcctgtca gcataaaaac atctaatcct
    10321 ttattctgga gctgcttgat tgcttgtttg acttctagtt tgatttgatc agccacggca
    10381 atcaacccga tcacttgctt ttcatcagct aaaaacatga ctgtttttcc ctgctgttct
    10441 aattctaacg cgtgttcttg gtattcatca aatgataggt tcaattcaat taatcgttta
    10501 cgtgtacccg caaaatagcg tactccgtta atcgtaccgc tgattccagc acctgggtgg
    10561 gctgtaaaat caatcatatc gtatgttgct gcttcttgca gttttccgta ttccacgatt
    10621 gctttaccta gtggatgttc agaagcttgt tctaaagtat aaaaaataga taggacttct
    10681 ttagaaccga ctagatctgt aactttgggc tttccttctg taatcgttcc agttttatcc
    10741 aaaacaatgc tgtctaagtg agcagctgct tctaatgctt ctccgccttt aattaaaatt
    10801 ccatttcgtg caccaacacc cgttcctacc ataatagctg ttggagtcgc taaacctaat
    10861 gcacatggac acgcaatgac taatacagag acactatgga tcaatgcgag ttgccaatca
    10921 ccagtgatca aacctgtagc tatgagcgtg ataaacgcga tgactaatac gatcggaaca
    10981 aaaatccctg agatccgatc tgcgattttt tggattgggg ctttgctccc ttgagcatct
    11041 tccaccattt gaatgatttg cgctaatact gtctgcttgc cgacttgtgt aacttccatg
    11101 tgaagtagac cattcgtatt gattgtcccg ccaaagagcg tgtcatccgg attcttttct
    11161 acaggaagat tttcaccagt aagcatactt tcatctatcg cactgcttcc tgaaataatt
    11221 cgaccatctg ctggaatctg ctcaccagga cggatgacta gttgatcacc aacgactact
    11281 tcttcaatcg ctaacgtttc ttctttcccg tttcttatca cttgggcggt ttttgtttga
    11341 agagacatca attgtttgat tgcattacct gttttcgttt ttgctgtatg ttccaaatat
    11401 ttgccgagca aaatcagcgt gatgatcata ctgctgcttt caaaataaag atcttggggg
    11461 tgtccacgga aaaatccgtt gtaaatgctc aatgcaaagg cagccgatgt tccaattgct
    11521 accaatacat ccatatttgg tgctttcgtc ttgattgcat ggtacgcacc tttataaaaa
    11581 cgagcaccga cataaaattg gacaggagca gacagcacta actggacgat tggaaaatga
    11641 aaaaagtgaa caatcgccgc atggcttcct aacatcatag caatcattga caacatcaac
    11701 ggcaaagtca aaaccgtact caatataaga tcgaatagca tttttttcaa atacgcttgc
    11761 ttttcttctg caattttttg tttgtgggct tcatcgtaca aaattgcacc atagccgatg
    11821 ttttctacgc tttggattaa tttttcagtg gtcgtccctt catatttgac acttgctttt
    11881 tcagtggcca agttgactgt ggcattgacc acaccaggtt gtccgttcag ctctttttcg
    11941 atcctagcag aacaatttgc acaagtcata cctgtaatga cgaacgtatc cattttggtt
    12001 tctgctgttg ccatcaaatc acctctgctt tataacccaa tccattgatt gcttgacaaa
    12061 tcttttcgga ttgaactttt gtttcatcaa acttgaccgt accgtttgct tttttcaaat
    12121 ttactttcac tttttgcacg ccgtcaagtg cgcttactgt ttcttctact cttgctgcac
    12181 aatgattgca gctcatacct tcgattgaaa attgttgttt cattttttct tcctcctatt
    12241 gatgttgttt acattcacat tgacctggga tacagttaca ttcgatcgta tctactggtt
    12301 gcttttgttc cagttgtttc aaaatctcat tgatatcttc ttgagtcaaa gtggcttctt
    12361 ctactagatc cgcaatcgtc tctccaatcc tttttgcaca gatatgggaa aaaagatttt
    12421 ccgtcgcact gcgaactgtt tccatctccg agacagctgg ataataaatg aatttttttc
    12481 cttcttgttc tgtccagatc acttcttttt ttaccaaacg acccagcaaa gttttgatcg
    12541 ttgctggttt ccaatccatc gaatcagcta agatctgcgt gatttcttgg gctgtcgtct
    12601 gtccaagtgt ccaaataaca cgcatgatct cccactctga atcactgatc tttactggcg
    12661 ttttgacttt ttccatttat ttcacacctt tcgtttacaa atgtaatcat tatcttatga
    12721 atacagatta cacttgtaaa caaaaactgt caattatttt tgctctctat tttcaattta
    12781 gttaaaaatt cttgtttctc tcgtcttgtt ttaaggatga tcagtttatt tcttgcatta
    12841 gctacttgga tcagctgctg tattttcggt tcattgtttt cttcaaaatg ccagataaaa
    12901 gataaaaatt ctaagtattc cctgtttagt ttctccgaaa atgattcagg catatctggc
    12961 cgagattttt tgtttatctt tctttttaga gaacgccaaa ctactcggta gatggcgaga
    13021 taacgcggca ctttaagcca aatgatctta tctgcttctt taatcctttc ctctaatgta
    13081 gaagtataat ttccttcaac gatccatgac ggattagata ccataaacaa ttgctgttct
    13141 tgcaaaaacc acttttttgc ctgaatactg tagtctgttg tatgccataa aaggtctagc
    13201 ggcagtagcg gaaagtcggt gatttctttg atcttccttg cgagggtcga ttttcccgac
    13261 ccactttgtc caatcacgat gatcttcatt cttctccctc acttctcttt ggaatttggt
    13321 tcgatcatac cacttataac gccgcaaaaa aacaagggac tgtgacaaaa gtcgtgtcaa
    13381 agtcccttgt ttcgaataa
//
LOCUS       DARBDN010000072        12945 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000072 DARBDN010000000
VERSION     DARBDN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.072"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="SCH06_002038"
     CDS             complement(64..1173)
                     /gene="rpoD"
                     /locus_tag="SCH06_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEG1078587.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1197..3038)
                     /locus_tag="SCH06_002039"
     CDS             complement(1197..3038)
                     /locus_tag="SCH06_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEG1078588.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3220..5535)
                     /locus_tag="SCH06_002040"
     CDS             complement(3220..5535)
                     /locus_tag="SCH06_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEG1078589.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5720..6580)
                     /locus_tag="SCH06_002041"
     CDS             complement(5720..6580)
                     /locus_tag="SCH06_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEG1078590.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6639..7160)
                     /locus_tag="SCH06_002042"
     CDS             complement(6639..7160)
                     /locus_tag="SCH06_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEG1078591.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            7438..8199
                     /locus_tag="SCH06_002043"
     CDS             7438..8199
                     /locus_tag="SCH06_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078592.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            8225..10816
                     /gene="mprF"
                     /locus_tag="SCH06_002044"
     CDS             8225..10816
                     /gene="mprF"
                     /locus_tag="SCH06_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEG1078593.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="SCH06_002045"
     CDS             complement(11004..12191)
                     /gene="tuf"
                     /locus_tag="SCH06_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEG1078594.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12559..12915
                     /locus_tag="SCH06_002046"
     CDS             12559..12915
                     /locus_tag="SCH06_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEG1078595.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         3713 a         2708 c         2300 g         4224 t
ORIGIN      
        1 tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt caatagtcca
       61 cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca attttcttaa
      121 tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt tccctacttc
      181 ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga cattctcttc
      241 ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact cataagctgc
      301 gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt gagagtcatc
      361 ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca agatttctcg
      421 gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag gttctcttcc
      481 aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt caaccatatg
      541 aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg cttgacgaat
      601 ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc
      661 cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc ctcgtcctac
      721 ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac gctgtttcgc
      781 ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg cagttaaaag
      841 ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt ttacaccggt
      901 tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac tcttcaagct
      961 gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt caatcttttg
     1021 gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct gattggataa
     1081 atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg ctactgctgc
     1141 ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt gagtagctat
     1201 ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc aagctcaagc
     1261 tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt tatttcatca
     1321 gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg cgaactttct
     1381 tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc atcttgcaaa
     1441 aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc atcgaataaa
     1501 aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt taaaatatta
     1561 cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt ttctacttgc
     1621 gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc
     1681 tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc
     1741 gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc ttgttcgatt
     1801 ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat cttgtctttt
     1861 tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg
     1921 cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag atattcatca
     1981 ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt ttgccgaagc
     2041 aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc
     2101 aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact tgtccccata
     2161 gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat aaacccttcg
     2221 aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag attaaataaa
     2281 acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg ctgatctttt
     2341 tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa
     2401 ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc atcatcatgc
     2461 gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt cttgaatact
     2521 tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc aattaattct
     2581 aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt tgtatgcaat
     2641 agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt ccccgtagca
     2701 gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa cggtatctgt
     2761 tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag ttcttgaaga
     2821 aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct
     2881 gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa gtaattttta
     2941 ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt ttgactgcgt
     3001 actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc tgctctattg
     3061 atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa atcgcactaa
     3121 ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat catatttcat
     3181 tgctttttca agtataacac atttctatct cattaagcat caatttgcta ctcttttcag
     3241 taactgattt tgaatatcag ccttccagta caatactcga agaacaatat ttacgagcat
     3301 gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca aaattccatg
     3361 gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga agatgcgcaa
     3421 tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa tcagcaagta
     3481 atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa gtagatacac
     3541 cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa gtgctgtagg
     3601 caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga aggaaggata
     3661 cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa atccaattgc
     3721 tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa aaaagatgcc
     3781 tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt ctggcaatgt
     3841 agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc catcaccttc
     3901 tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca caccgtcgcc
     3961 tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt tcttttgctg
     4021 cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt ccatttcttc
     4081 agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac gtctagcgat
     4141 attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac cttcctcatg
     4201 aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt caaacagagc
     4261 aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag cgatccccaa
     4321 cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc
     4381 ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa attccatcgc
     4441 gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc gattagaaag
     4501 ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt ctgccagata
     4561 cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt ctacccgctg
     4621 gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg tatcgacatg
     4681 ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg ccagtttggt
     4741 tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa gcatgcctaa
     4801 caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga tgaacagtgc
     4861 ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt
     4921 gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct cgctagtcaa
     4981 gcggacagca taattatctg cacctactcg gataacttca gccatgacag aaccgcttgt
     5041 caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat cagattcgcc
     5101 tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat cggctggtat
     5161 ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag tagaaatcga
     5221 ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg ataatttccg
     5281 tacaagattt cttgcatgta tttcttgata aattccaata acgatattga cgacaataat
     5341 tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc caataccaaa
     5401 gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg tactttttga
     5461 tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta cctcttgctg
     5521 tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa taatcacgtg
     5581 tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt tatagaaaaa
     5641 cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt
     5701 ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc caccaaccta
     5761 gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact cccaatcccg
     5821 cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa atgaaatgga
     5881 atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat ccaagaacac
     5941 aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct ttaaatccgt
     6001 cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc aatcctggga
     6061 cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa ttctgatcga
     6121 cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga acaaaagtaa
     6181 caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct ttccataacg
     6241 caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt tcatacgcac
     6301 ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg cctagaccaa
     6361 caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct aaaaaagaaa
     6421 tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact cctggcaaga
     6481 taaatcctga accgataaac attcccttca caaaccgtaa catccagtct ttggttgtgt
     6541 accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgca ctccttcttt
     6601 catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac tttttcatag
     6661 gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt acctccatta
     6721 tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg gtattgtttc
     6781 ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc tgctaattct
     6841 actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc aaaattatat
     6901 gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat catttccgcc
     6961 aaatatttga caccttgatc aatactgtca gctggattat caatgatctc agcttctcca
     7021 tgcagacttt ccgagctctg catgagatct gtcccttttc cttttgattc ggtcaatatt
     7081 atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc tgttgttatt
     7141 tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctca taaaaacaac
     7201 accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat agataatcgt
     7261 tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac tatttcttta
     7321 tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat gaattttcct
     7381 gtattttttg acatcttacg aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg
     7441 actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga aaagaaatat
     7501 gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg cttccctctc
     7561 tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt ccctgtactc
     7621 gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc gacaaacgaa
     7681 gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat gttgctggaa
     7741 aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc actggtattt
     7801 gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa cacgcttgtt
     7861 aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg ggtatggtta
     7921 ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact tttgctgcat
     7981 gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt gatcatcgtg
     8041 ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac tataccaaaa
     8101 gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga tcctgaacgc
     8161 ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat agaaggtgat
     8221 ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt tcaaaacaat
     8281 ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg gtaaaactct
     8341 atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa gcggactaat
     8401 gctattgatt ggtcttatct ctgtgttacc tatggttggt tatgatatta ttttgaatcg
     8461 gatgcttgaa caaaagcaga atcctcgtta cctgtttgag acaagctggc tgatcaatac
     8521 gatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct ctgaactata
     8581 tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt
     8641 gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct tcacgccagt
     8701 tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat attttcctgt
     8761 cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct cacttaaaac
     8821 tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct
     8881 ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc cattattcat
     8941 tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga gtttcgatgt
     9001 aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat
     9061 cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg tctttttctt
     9121 caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac aattagcaac
     9181 agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca tgctagtact
     9241 ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt tgaacccatt
     9301 gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt taatcattat
     9361 gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct tcttgattgt
     9421 tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg ttttcttgtc
     9481 tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac aattgatcta
     9541 ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct tgctttacat
     9601 cgttattggg gtatacaatc tgccggattt ccctcatcgg cgtcaccatt ttatttcctt
     9661 tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca tcgctgttag
     9721 tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc
     9781 ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact ccgatagtca
     9841 attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg aaccaactgt
     9901 tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc cttctggtaa
     9961 gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc gactatgcta
    10021 tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg aattcggcta
    10081 cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta caacttcagg
    10141 gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag gatttacatt
    10201 tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa atatctctga
    10261 taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct ctgaagatta
    10321 tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc
    10381 aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga tgcgatatga
    10441 ttctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt ttgcctatat
    10501 gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa atgtcggaac
    10561 ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt ttggttctca
    10621 tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa actgggtctc
    10681 acgttatact ctatattcta gagatagttg gattgcatat gttatgattg ctttgctgat
    10741 tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga aaaaatggat
    10801 acgaagaaag tattaaaaac tgcataccga tagatgaaca ctctcatgat gaataaaaga
    10861 gactgaagta aaacgaaagt tcatgcttct acaatctctt cttatacaat tgaagaacaa
    10921 agagcggtcc aaacagaaat cctgtttgga ccgctctttt attttaaaca tttttcatta
    10981 ccaaaatatt cgagtcgcgt ttcttatgct tcgatctctg taacgatacc tgaacctact
    11041 gtccgtccgc cttcacgaat tgagaatgtc gttccgtttt caacagcgat tggatggatc
    11101 aagtcaacat caatcgtcac gttgtcacca ggcatgacca tttctgtatc ttctggcaat
    11161 gtgattgttc ctgtaacatc agttgtgcgg aagtagaact gtggacgata gttgttgaag
    11221 aatggagtat gacgtccacc ttcttctttt gtcaacacgt acacttctgc tttgaatttt
    11281 gtatgtggag taatggaacc tggtttagca agtacttgtc cacgttcgat atcgtcacgt
    11341 tggatccccc gtaacaacac gcctacgtta tccccagctt ccccgtaatc taacgtttta
    11401 cggaacattt ctacacctgt tacaactgct ttttgtgttt caggtttgat ccctacgatc
    11461 tctacctcat caccgacacg aacagcacca cgatcaatac gacctgaggc aacagttcct
    11521 cgacctgtaa ttgagaagac gtcttccact ggcaatagta atggtttatc tgtatcacgt
    11581 tctggtgttg ggatatattc atctactgta tccatcaatt ccataatagc agcttcagca
    11641 tctggatcgc cttgcaatgc ttttaatgcg gaacctttga tcacaggagt gtcatcgcct
    11701 gggaaaccat attcgctcaa taactcgcga acttccattt ctaccaaatc gatcaattct
    11761 tcatcatcga ctaaatcaac tttgttcaag aaaacaatca ggtattttac accaacttgg
    11821 cgtgacaata aaatgtgttc acgtgtttga ggcatcggac cgtcagttgc agaaacaact
    11881 aagattgcac catccatttg tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt
    11941 cctggtgcat caatatgcgc gtagtggcgt ttttctgttt catattctac gtgtgcggta
    12001 ttgatcgtaa tcccacgttc acgttcttct ggagctgcat caatactagc atagtcttga
    12061 ggatttgcta ggcctttttt gcctaatact gtagtgatcg cagcagttaa agtagttttc
    12121 ccatggtcaa cgtgtccaat cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt
    12181 tcttttgcca taatttacaa acctcctaaa taatatagat cactgaaaaa tttcagctct
    12241 caccttttta ttatagtctt tttttgacta aatcaaaaag aatacgtccg acttactttt
    12301 tgtaagattc gaactaagct tattatacgt caatattggt caaagtcaac taagagcact
    12361 cgtctgtctt atacgcgaaa aaagtacctt ttataaataa aaaaatgtgt tttttgagaa
    12421 aaacttcaag atagtcctta actttctttt gaagcaataa gaacaaaatg aggaaaagtt
    12481 taaaattcag ctgttgccaa caactttcaa tagacgaaat cttctatttc gttaataata
    12541 aggaaagagg tgaagtacat gaaaaaatta attggcgtac ttgtcgtttt aggcatattt
    12601 ctcggcggaa gttttgcagc ttatcattat ttttacggcg gcgaagctta ttatacaaaa
    12661 atcacgacga atggcgaaat gtcagctacc caagcagata acggagagaa attcacgact
    12721 tatacctaca agcaagcggc ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc
    12781 gaagaaagag aacatccatt aaagatgaat gcgtatctta aactcaaagt caatcctcgt
    12841 aaaggtgtat taagctggga agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa
    12901 aaaatcgata attagtaaat ggtcttaaaa ttttattaga taaaa
//
LOCUS       DARBDN010000073        12838 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000073 DARBDN010000000
VERSION     DARBDN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.073"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            6..305
                     /locus_tag="SCH06_002047"
     CDS             6..305
                     /locus_tag="SCH06_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078596.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="SCH06_002048"
     CDS             378..1739
                     /locus_tag="SCH06_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEG1078597.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="SCH06_002049"
     CDS             1761..2021
                     /locus_tag="SCH06_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078598.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="SCH06_002050"
     CDS             2035..2787
                     /locus_tag="SCH06_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEG1078599.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="SCH06_002051"
     CDS             complement(2881..3486)
                     /locus_tag="SCH06_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078600.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="SCH06_002052"
     CDS             complement(3539..4513)
                     /locus_tag="SCH06_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HEG1078601.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="SCH06_002053"
     CDS             complement(4891..5610)
                     /locus_tag="SCH06_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1078602.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SCH06_002054"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="SCH06_002054"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEG1078603.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWIVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="SCH06_002055"
     CDS             7161..8558
                     /locus_tag="SCH06_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1078604.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="SCH06_002056"
     CDS             8639..9079
                     /locus_tag="SCH06_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEG1078605.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="SCH06_002057"
     CDS             9227..9553
                     /locus_tag="SCH06_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEG1078606.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="SCH06_002058"
     CDS             9554..10303
                     /locus_tag="SCH06_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078607.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="SCH06_002059"
     CDS             complement(10383..10838)
                     /locus_tag="SCH06_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEG1078608.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="SCH06_002060"
     CDS             complement(11265..11540)
                     /locus_tag="SCH06_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078609.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="SCH06_002061"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="SCH06_002061"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEG1078610.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4109 a         2211 c         2621 g         3897 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aatccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagctt
//
LOCUS       DARBDN010000074        12773 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000074 DARBDN010000000
VERSION     DARBDN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.074"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(367..729)
                     /locus_tag="SCH06_002062"
     CDS             complement(367..729)
                     /locus_tag="SCH06_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078611.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(803..1183)
                     /locus_tag="SCH06_002063"
     CDS             complement(803..1183)
                     /locus_tag="SCH06_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEG1078612.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1247..2440
                     /locus_tag="SCH06_002064"
     CDS             1247..2440
                     /locus_tag="SCH06_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEG1078613.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2517..3101)
                     /locus_tag="SCH06_002065"
     CDS             complement(2517..3101)
                     /locus_tag="SCH06_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEG1078614.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3302..4300
                     /locus_tag="SCH06_002066"
     CDS             3302..4300
                     /locus_tag="SCH06_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEG1078615.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4412..4921
                     /locus_tag="SCH06_002067"
     CDS             4412..4921
                     /locus_tag="SCH06_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEG1078616.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4951..5610)
                     /locus_tag="SCH06_002068"
     CDS             complement(4951..5610)
                     /locus_tag="SCH06_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEG1078617.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5612..6376)
                     /locus_tag="SCH06_002069"
     CDS             complement(5612..6376)
                     /locus_tag="SCH06_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEG1078618.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6384..7061)
                     /locus_tag="SCH06_002070"
     CDS             complement(6384..7061)
                     /locus_tag="SCH06_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEG1078619.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7098..8483)
                     /locus_tag="SCH06_002071"
     CDS             complement(7098..8483)
                     /locus_tag="SCH06_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEG1078620.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8693..8777)
                     /gene="ffs"
                     /locus_tag="SCH06_002072"
     ncRNA           complement(8693..8777)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="SCH06_002072"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8800..9315)
                     /gene="tadA"
                     /locus_tag="SCH06_002073"
     CDS             complement(8800..9315)
                     /gene="tadA"
                     /locus_tag="SCH06_002073"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HEG1078621.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9422..10279
                     /locus_tag="SCH06_002074"
     CDS             9422..10279
                     /locus_tag="SCH06_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1078622.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10360..10695)
                     /locus_tag="SCH06_002075"
     CDS             complement(10360..10695)
                     /locus_tag="SCH06_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078623.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10762..12132)
                     /locus_tag="SCH06_002076"
     CDS             complement(10762..12132)
                     /locus_tag="SCH06_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HEG1078624.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12210..12746)
                     /locus_tag="SCH06_002077"
     CDS             complement(12210..12746)
                     /locus_tag="SCH06_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1078625.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         3792 a         2592 c         2132 g         4257 t
ORIGIN      
        1 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
       61 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      121 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      181 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      241 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      301 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      361 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      421 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      481 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      541 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      601 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      661 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      721 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      781 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
      841 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
      901 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
      961 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1021 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1081 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1141 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1201 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1261 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1321 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1381 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1441 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1501 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1561 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1621 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1681 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1741 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1801 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     1861 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     1921 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     1981 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2041 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2101 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2161 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2221 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2281 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2341 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2401 acttaatcga atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa
     2461 ggacgagacc ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat
     2521 tctgaaattt caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt
     2581 tgtacatttg cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta
     2641 tgtcggaaat ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg
     2701 aatccagcac cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata
     2761 aagaattggc ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg
     2821 ttgaacagtt cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc
     2881 attcctgttc cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa
     2941 atcacgccat cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt
     3001 gctagttcag ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt
     3061 ggtccttttt cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt
     3121 tgcatacttc ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt
     3181 tttcttttat ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca
     3241 aacatttttg agaagcattc tcaattaaat tctgctatag tgtgaaaagg gaggaatttt
     3301 tatggaaatc tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt
     3361 ttacgcagga atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg
     3421 tcaattagca actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat
     3481 aaaagcaagt gaattaatcg atcaattaga aaaacaatta actactttta accatacatt
     3541 ccatttaaaa gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac
     3601 aaataaaggc atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca
     3661 gccaagaaaa ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt
     3721 cgtgaatgat ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc
     3781 tgctatcgat tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg
     3841 tcgcccggaa tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa
     3901 cttgcttact ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat
     3961 ccggttaaaa aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt
     4021 caattatgga ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag
     4081 aaatgccatt actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg
     4141 tgacatctgt acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc
     4201 tactgcagtg aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca
     4261 cagcacaagc ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat
     4321 ttcaagttaa acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata
     4381 gagaaagaaa aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga
     4441 aaaggcaaga gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt
     4501 catgttttta caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt
     4561 caacagcgtg ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga
     4621 tatattagca gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga
     4681 aggcctttac ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat
     4741 cggctttacg aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa
     4801 cagccacgat ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc
     4861 tgctgctgcc agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata
     4921 attcaacaaa aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt
     4981 caagctattt tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa
     5041 taagataaag ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac
     5101 gggatcgaat aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg
     5161 atcaaatcct atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa
     5221 cggacgaatc aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact
     5281 cgggatcaaa gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata
     5341 aaagtgatgg gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa
     5401 gggattattg agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa
     5461 agaagtataa tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt
     5521 gatcgtcaca ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata
     5581 ttccatccac tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt
     5641 tcacataggt agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata
     5701 aaacgagcaa agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat
     5761 ctccaaccat gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa
     5821 tgatggcttc tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag
     5881 agatgactga ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt
     5941 tcgttccaat gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat
     6001 aggtcagata attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa
     6061 atccggcagc taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc
     6121 cttttccatc tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg
     6181 gagctacatg aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag
     6241 tcgtgttatt ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc
     6301 gtttaccggc cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat
     6361 atcctttata gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt
     6421 gttttttcta cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac
     6481 tctgtttttc gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc
     6541 tcatcgatat acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct
     6601 tttttaccgc cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa
     6661 agatagtctt ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg
     6721 aaaaatcctt ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg
     6781 gctagtacat cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg
     6841 gacacaagcc gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact
     6901 agctcgcctt tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc
     6961 agttcttcgg tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt
     7021 ttatgctcaa cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt
     7081 tttattatac cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca
     7141 cttcggataa attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa
     7201 aatggaacaa acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt
     7261 ggcttgttct tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc
     7321 atctgcccaa aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag
     7381 ttacgatttt tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca
     7441 tttaacaagt gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct
     7501 tttggaattt cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt
     7561 tctttcaccg cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc
     7621 agagaaaatg gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga
     7681 taactattta tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct
     7741 ttggctgaat gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca
     7801 tactgcccgt actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg
     7861 aataaatgat gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt
     7921 tggaaatcat cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt
     7981 aaatcttcga ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga
     8041 ttataagtaa gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc
     8101 gttgtaatga ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat
     8161 aagttatcca ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg
     8221 gaatttccta cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc
     8281 agcaagatat tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa
     8341 tcacctagat ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt
     8401 tgatccaaaa accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta
     8461 tgtaaaatca ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata
     8521 ggcagctttt tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa
     8581 attgtataag tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt
     8641 tacagtacta taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc
     8701 agacacatgg cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc
     8761 ccaccattgt cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca
     8821 gtcttttttt aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat
     8881 cccacattcg tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc
     8941 ctccaaaaga ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata
     9001 aacttctgct acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt
     9061 aacaaaaagt gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat
     9121 tgcaagcatt tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct
     9181 tccaatcact tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc
     9241 tgctttcttt gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag
     9301 atttgtattt accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat
     9361 gataaaaagg ctgtaactaa cttttttttc tatggtaaaa taaatacaag aggtgaacaa
     9421 gatgaaaatg gataaattac ttgctcttta cccacaagca cagaaaaaaa actctccagc
     9481 atcagaagcg gatatccttt cttttgcaat tgatgatgct tttatctgga tcaaacaaga
     9541 ttcattatct caacaagaaa ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca
     9601 aaaaaaacac ccatggtatc gctatctttt taaagatgct tcttgtgttc aagaaaaaag
     9661 ctttcgtttg atccagcttc acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca
     9721 agatactatt ttggaattat ttcgctattc tgctgatttc tttttttata cagacacaga
     9781 tgcgctctta gtcgaacaaa taaaccgtga ttatcttgat gctactgaaa tcaacggtat
     9841 ttttctatct ttagatgctg attttgatac gacaacgtct gtattcgttg gttctttcca
     9901 ttcacctggc accgacctcg tccctttgtt tgctgaagaa agaaaaattt ttttaacaga
     9961 gcaaaacaat ctttatactc acagccgtac tttttctatg caagatgtgg ctttacatta
    10021 ctatacaaaa gatactgtaa aagatagtaa gttgatcaaa agttacatag aactgatcaa
    10081 acaaaatgaa atggaagtga tcattcaaga attatggaat gaattaggca atgtcagctc
    10141 tgctgcaaaa acactgtttc ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca
    10201 agaacagtct ggtttcaatc taaaaaaagc caacgattta ctgttttgct atcttttatt
    10261 gcttcatgaa cataattaaa gatagattaa aggggttgtg acaataattt tgtcacaacc
    10321 ccttatttcg aatgaatagt gttcaaaagc tagtttctct tacatcattt tttcaacaaa
    10381 atgcattagc cggtctttta catcttcggt tgaatctttg attgaatcac cataaacaga
    10441 gattttcttt tttcctgatt tgatttttgc taacattccc atcaaagaat ccaagtcact
    10501 atctgaaaga ccatctacga tttctagtaa tttttcattt ccatcaaatt tgtcatagac
    10561 gaattttttt actttcgtcc gagtagtcat atgatggatc ttttccatta cttttcccga
    10621 tacaacgact gctgtcgcta cactggcagc ggctgctacg cttaatccga ttgttacttt
    10681 tgttgatgtt ttcataagta tcagctcctt tttatctatc tccatcatag catagacaaa
    10741 aaaataaacg aactaatcca ctcagtgaaa tctcaatcct ttagggaaaa agttctttac
    10801 tgttcctttt acttgtttcc caaatccgac aggtatctta tctaatacta gcaaaaccca
    10861 tccttgattc ccatcacgtt gaaatgtttc tcctgctgtg taagattgcc attccttttg
    10921 agtgatcggc aagcaaggta tattctctat cttttttgta gcaagcgcta atgcatagct
    10981 aggttcaaat cgattctttt tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa
    11041 accatcgaga gaaggggcta actcaggaac ttcccaaaga tggtcgttga acactaaaag
    11101 tcttccagta gcttcataat gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc
    11161 ttttgtcatt tgcactttac ttttttttcg tgtcttcttt tctttatgca tctgattttg
    11221 tccatgaaaa gtcagctttg caacaaaatg tccttcaccc tgatctttat gaggccatat
    11281 acgtattgtt ttttccaaac cagctacgct tccccattca gaacgtcctg aactaacgga
    11341 ttgagtcaaa ggaatctcct caatcgttac tggataattt tctacaagcc agctaatgat
    11401 ctcttcattt tcttctggtg caaacgtaca agtcgaataa atcagttgtc ctttattttt
    11461 tagcattttt attgctgaag acaaaatctc ttgctgacgt ttttgacagt atagcggaga
    11521 ttcttctgtc cactctttta ttgcatttgg atcttttcgg aacattcctt ctcctgaaca
    11581 aggagcatca accacgatcc gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg
    11641 tgcatgattt gtcactattg cgttcgaaac tccccatcgt tctatatttt ctgataaaat
    11701 cttcgcacgt ttcggaaaga tctcattcgt cactaataac cctttcccct tcatttgagc
    11761 agctaattgg gttgatttac caccgggagc cgcacacaaa tccaaaactt tttcaccggg
    11821 ttttgctgca gcagctgttc caacgatcat tgcacttggt tcttggctat attcataccc
    11881 agcttgatgg aggaaagact ttccattgac agtgccaaga aatccctcat tgctgtaggg
    11941 agcgggttgt aattcttcgc tatggtaagt ttggaccatg tccaatcctg ccggttttag
    12001 tggattccac cgaaatcctt ttttcacgct tccttgttca agcgcagaaa aaaaatcgga
    12061 tgcttcttcg cctaaaagaa gacgatattt tttgataaat tgctgtggta acgttgtcgc
    12121 ttcctccttc attccaatgt ttcgttagac attttacaat cttttttacg aaaaataaag
    12181 gtggctgatc tactttttca tgttgctgcc taaggtgact gttcctttaa gatattttcc
    12241 aagtattcat ccgtcacctc gtttttatcc caaacagcgt tcatcatttc aagaaaatct
    12301 tgagaagaat catctgagcg caaacttccc aatgcattaa gccataccaa ttcaagcgac
    12361 ttttcttctt tgatcttcgt gtgacctttg acatatgaga aaaatggccg cttaaatagc
    12421 gaatccatgt ctaaatcaga ttttgcaatg atttcacgaa tactttcatg gatagaaaaa
    12481 aaatctttca ataagtagac aatgcttaaa acatcatcgg aactgcattc agctaagtag
    12541 ttttcaaaat aaacagtgat ttcttctaat atcttctctt ttaacccgct gattgatttg
    12601 aaatgtgtat aaatcgggta tgtagaacaa ccgcagaact ctgctaactc tcttgcagta
    12661 attgacttca ttccatattc ttccacgtat accatacttt tgaacagcaa atattcttta
    12721 ctataatttg ttactctccc catcattctt acctccgtct cttttcatct acc
//
LOCUS       DARBDN010000075        12734 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000075 DARBDN010000000
VERSION     DARBDN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.075"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SCH06_002078"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="SCH06_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEG1078626.1"
                     /translation="MAVLARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="SCH06_002079"
     CDS             complement(322..891)
                     /locus_tag="SCH06_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEG1078627.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="SCH06_002080"
     CDS             1077..1979
                     /locus_tag="SCH06_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEG1078628.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SCH06_002081"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="SCH06_002081"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEG1078629.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SCH06_002082"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="SCH06_002082"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEG1078630.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SCH06_002083"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="SCH06_002083"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEG1078631.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="SCH06_002084"
     CDS             8547..8732
                     /locus_tag="SCH06_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HEG1078632.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="SCH06_002085"
     CDS             complement(8794..9990)
                     /locus_tag="SCH06_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEG1078633.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVARAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="SCH06_002086"
     CDS             complement(10160..11596)
                     /locus_tag="SCH06_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEG1078634.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="SCH06_002087"
     CDS             11889..12698
                     /locus_tag="SCH06_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078635.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2674 c         2249 g         4008 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctagtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcac gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gaca
//
LOCUS       DARBDN010000076        12306 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000076 DARBDN010000000
VERSION     DARBDN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.077"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            286..693
                     /locus_tag="SCH06_002088"
     CDS             286..693
                     /locus_tag="SCH06_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078636.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            707..1108
                     /locus_tag="SCH06_002089"
     CDS             707..1108
                     /locus_tag="SCH06_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078637.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1110..1481
                     /locus_tag="SCH06_002090"
     CDS             1110..1481
                     /locus_tag="SCH06_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078638.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1517..1816)
                     /locus_tag="SCH06_002091"
     CDS             complement(1517..1816)
                     /locus_tag="SCH06_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078639.1"
                     /translation="MLFNETQLWFKFDPTNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1822..2052)
                     /locus_tag="SCH06_002092"
     CDS             complement(1822..2052)
                     /locus_tag="SCH06_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078640.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            2669..3331
                     /locus_tag="SCH06_002093"
     CDS             2669..3331
                     /locus_tag="SCH06_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078641.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            3410..6635
                     /gene="fss3"
                     /locus_tag="SCH06_002094"
                     /pseudo
     CDS             3410..6635
                     /gene="fss3"
                     /locus_tag="SCH06_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
     gene            6749..7063
                     /locus_tag="SCH06_002095"
     CDS             6749..7063
                     /locus_tag="SCH06_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1078642.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            7076..7450
                     /locus_tag="SCH06_002096"
     CDS             7076..7450
                     /locus_tag="SCH06_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1078643.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            7460..7804
                     /locus_tag="SCH06_002097"
     CDS             7460..7804
                     /locus_tag="SCH06_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEG1078644.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            7875..9227
                     /locus_tag="SCH06_002098"
     CDS             7875..9227
                     /locus_tag="SCH06_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEG1078645.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            9287..10429
                     /locus_tag="SCH06_002099"
     CDS             9287..10429
                     /locus_tag="SCH06_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEG1078646.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            10454..10708
                     /locus_tag="SCH06_002100"
     CDS             10454..10708
                     /locus_tag="SCH06_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078647.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            10964..12148
                     /locus_tag="SCH06_002101"
     CDS             10964..12148
                     /locus_tag="SCH06_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEG1078648.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            12145..12282
                     /locus_tag="SCH06_002102"
     CDS             12145..12282
                     /locus_tag="SCH06_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEG1078649.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         4168 a         2017 c         2646 g         3475 t
ORIGIN      
        1 gaggggaagt acatatagtt gttgatatag ttgctaatat tgttagctaa tttgttagta
       61 aaactgtata cgaatttaga tagtaaaaaa acagtttgtt ccttatatag aggcactttt
      121 actactgatt aaatgtcaga tatgcttaca aatatactta taaatatgct tacaaaatta
      181 gctaatattt ccgttgacaa agctttgtta ctattgttaa actaaattga ctagcaaaag
      241 tgaaacataa atttattaaa taaatgtaaa aattaggaga aatcaatgtc ttatagagta
      301 caattaataa tttcagaaga tgtagaaagt cagcaatttg gcactaatgt tattaataaa
      361 gtaattaatc cagctctttc tattaatgcg cctttaattc ctactgcttt atcattttct
      421 gtaacagctg tggtgtctga gatagaggat acagaaaaga taaaaatagt agaaattgaa
      481 gttttaaaca agaatgaaaa acaaattttt tctacgggtg aagtatcggt aagcttgcct
      541 cctcaagtta acgatataaa ctttaatata aacgccagaa atgtcttggt tgaagaagca
      601 ggagagcatt atgctgttgt taaatttaat ggaactgaga ttggaaggca aatctttgat
      661 atcaaggtca acaaaccagt ggaaaaaaat taaggagacg atacggatgc ttgatatagt
      721 accatcaaat acacatcgga gtggtagctt aataaatttt gctgcgattt ttgcttgcgc
      781 atcggtaatt ctagcatctc cagttgttgt ggatgcaagt tctactccga aaactaaaaa
      841 tgataatcaa cttgtaatta ctacaaaaaa tgagattaac acaatttcaa gtaatgatgg
      901 caaaattttt gatgtgataa atacggtttt aaaaagaaaa gctgaaatca atataaaata
      961 tgatgaagat ttaaacttgt atttctttgt tatcaaaaca acatctgaat tgttttcctc
     1021 agattacgat gttttggata ctctcgataa tgtattatct gactataaat atatggggaa
     1081 atctgtagta gcaactttgg gggaataaaa tgtttgactt taatgaatat ttatctattt
     1141 ccaaacaaat tgaatcagat gataaatata attctaaaga atcttataga agaactgctg
     1201 tttcaagagc atactacagt gcttttaaaa aatctgatga gtatttgaaa gaaaattatg
     1261 atattattta taatggaagt agcggaaaag gaagccacca aaccgtttgg aatttgtttt
     1321 caacagttaa ggaattgaat accttaggaa tacataatag tgggtataga atgttagaga
     1381 aaagaaaatg tgctgactat attcctaatg aaaccattac gaaaacagat atggcgctga
     1441 tgaatcgaga agcagaaaaa ataataaaca aactcaccta atgaatttca agcgagtttg
     1501 tttgttattt ttttatttaa tctttgtatc tttctggatc aacgaaagta tactttatat
     1561 agtcataacg ccgatgatcg ctacgtgcgt ccggcacgtc agtcacgata tcaaacaaaa
     1621 agtatacacc cttcttcatt ctagttttcg cagcaggaat tttgaaatag ttcttattag
     1681 aatagtagag attgattaat aagctatctt cgattgctaa aaagaaaact tctgaattcc
     1741 atactttata aaaatctttg ataaatctat tcgtaggatc gaatttaaac cataattgtg
     1801 tctcattaaa aagcataacc attactccga tctgttttta aaattagttt ctacctctaa
     1861 tatatatcga gtttttattt tgccttcaga gaatactgtt tctttttttg cagttacagg
     1921 ttgtttattt tcggaaaaag ctaatatagc taaaattgaa acatccatct ggaatttatc
     1981 ttttttgctg ctttgctcat aaaagtctgc atattcatca ctgatatttt ttctaataaa
     2041 gtcttccatc ataaaaatca cctcaaaacg attatacgaa cttacgttct cgttgtaaag
     2101 cgatatttga ggggcaaaaa gggggcaaaa atacgtttat ctttgatata tctcagattg
     2161 aacatagtgt ttattatatg tcggtattgt tgatttatag ctgttttgag ggtattagat
     2221 acataataga atatagtggt tttgtttacg tgcattacac ggaaaagctg ctcgtatcaa
     2281 agaaatcaga agataaacac ggaaaacttc cttggaaatc tgaaatttgt gaaaagtcct
     2341 tgtatatcaa gggctttttc ttttttctct atcacagttt taagccattt ttggctgttt
     2401 tggaccattt ttcaatcata ttcccttaaa aattgtccta gattgtccga cattgactat
     2461 cagtgtcgtc aaaatagggc aaaatttagt agtcagcttg acgacaaata taatacgaaa
     2521 aataccaaaa catttaccga atttagcaac ttttgaaccc aagtttctca aagggtcagc
     2581 tattagcaaa aaagacaaaa catgtacttt tctactaaaa agttgatgtg ataggcttct
     2641 atctaaataa ctattaggag tttttatcgt gaagcaaaat gatggacgta tcatttggaa
     2701 aaatcaaagt gagttaaaac tgattttaac aattaatgaa ttcatcgaaa aacacggaat
     2761 tacatctagc cgtcaatacc agaaaaagct atcagaaaat ccaaattctg caccaagtat
     2821 gtggttcatt aacaaaaaat atggatcatg ggagaattta ttgattagta taggacgaga
     2881 aaatactggg tatggaaaat gggctagaat gtcagaacaa gaattattgg aaatagtaga
     2941 agcctttatt aagtgcgaga agataacctc tcaacgaatg tacgaacaaa aatcagtagg
     3001 gaagaatatt ccttcactta gtaccattaa aaagatgtta ggagatatac gtccactttt
     3061 taaagaaaaa aatgatggat ctcgatttac tgatttcgaa ctgctgttag aactaaaaaa
     3121 tgaaataatc cgattaaaac tacaggatga tttatcaatg acaaagtttc gaaaactagt
     3181 tcaatcccca aaactaccat cagttgatac aattatgaaa agaacgaaca aaaattggga
     3241 ggaattgatg gcagagattg gatttgatta tcgaagaatc aaaatttata agcagagaaa
     3301 caacctatcc aagacaaaga aaactaaata gtatcactct aaatcagacg ttcaaaatta
     3361 aaatttggac gtctttttta ttacccaaaa acgaaaggag atttatttta tgaaaaagcc
     3421 aagatttaag aattggcgtt tgctcgcaac actgagtcta ttatgccaaa caattggtgg
     3481 atcgcttggc ccaacgattg cctttgctga tgaaattact catccacaaa cggtaactgt
     3541 ggaattggat ttggctcacc agtatgctgt cgaaggtaca tttagcgatg gtcgtcccat
     3601 gtcagaagtt accgttccgc actatgcagt ttacaatggt gtgaagcaag atattttctg
     3661 tattgagcca ggggtgccga tttacaatga gttcactcct ggttatgaga aaaatccatt
     3721 gcctgatatg tcggagaaag cgaaattagt ttccgtttta tggaaggaag ctggtacgga
     3781 tgtggataca catattgtgg cccagaagat gatttggcaa gaagttaatg gctacgcttc
     3841 actcaattaa acgttctgat ggtagtgcag taaatatcgc agccattgag tcaaaaatca
     3901 atcaagccat tgcggattat caaaagaaac caagcttcca taactccaca gtgaaaaccg
     3961 tgttaggtca atcgactact gtgacagata cgaacggctt gaatttatcg gagtttgatg
     4021 aagttgtcga gaatatcgca aatattgatt atcgtgtgaa cggcaatcaa ctagtgatta
     4081 ctccaaatgc caattcaaaa gagagtggtg aattaaccct aaagaagtca gctaatacag
     4141 gaacaccggt agcttataaa atggctggtc aacaaacttt gatggcgggg gcaattgata
     4201 agcccaatac ctacacaatc aaaattgatg tggaaactga gggttctttg aagattaaaa
     4261 aagtcgataa agaaacagga aatgttgtac cgggaaccgt tttccattta gactttggaa
     4321 aaacattacc tgcaaaagac gtgaccaccg ataaagaagg cattgcgaca ttggatgaga
     4381 ttcctcatgg cgcgaaagta accattactg aaaaatcagt gccagctcct tatacgattg
     4441 acactacacc aatcaccgca accattaaat ctggtgagac tatttctgtg acttcaaaaa
     4501 atactcgcga aaaaggtcaa atcattttga ataaaatggg ggtggaaaca ggaactgatc
     4561 tttggaacga caaatactca ttagccggaa atacgtttgc cattcgcaaa gacagtccaa
     4621 ccggtgaaat tgtccaagaa atgaccacgg atgaaaaagg tcatgcggaa acaccaaaag
     4681 agattgccaa tgcgttggaa ttgggaacct attatgtgac cgaaaccaaa gctagtaatg
     4741 gctttgtgaa tacctttaaa ccagtaaaag tcgaattgaa ctatgtcaat caaaccgtgg
     4801 ctcttgttac cagtaacgta aaagggcaaa accaagaaat cactggtgaa accactttga
     4861 caaaagaaga caaagatacc ggtaatgaaa ctcaaggtaa agctgagttt aaaggagctg
     4921 aatatactct ctttactgca aaagatggtc aagcggtcaa atggagtgag gcttttaaac
     4981 cagagttagt gaagggaacg aaagcttctg atgaaacggt gactttgact ttagatgaaa
     5041 agaatcaagt tgctgttaaa cacttagcga ttaatgagta ttactggcaa gaaaccaaag
     5101 cacctgaagg atataccttg gatgaaacaa agtaccctgt ttccatcaaa aaggtggatg
     5161 ataacgaaaa aaatgccgtg attacccgag atgttacggc aaaagaacaa gtcattcgct
     5221 ttggctttga tttctttaaa tttgctggat cagctgctgg gactgccgaa actggcttca
     5281 atgatctgac ctttaaagta tcgccattgg aaggaaccag tgagattaca ggtgccgaag
     5341 atgaagcaat tacagcttat aacgagcaac taggttttga tggctatggc aagtttgaaa
     5401 atcttcctta tggggattat ttacttgaag aagtagaggc tccagaagga tttcaaaaaa
     5461 ttacgccatt agaaatccgt tctactttta aagaaaataa agcggattac actaagagtg
     5521 aatacatttt tacgattacc gaaaaaggac aaaaacaacc aattaaaacg gtgaccgttc
     5581 cttacgagaa actgacgaat aaagcatttt ctgttagctt gaatcgtttg atgctctatg
     5641 atttacctga agaagaagat agcttaactt ctcttgggac ttggaaagac ggaggcaaag
     5701 aattgacaga ccttgattct accgagctag ttgataaatt gagctataac ttgcatgaaa
     5761 tcaaagaaga ctggtatgtg gtagcgcaag ccattgatgt ggaagcgaca aaagctgccc
     5821 aagaaaaaga tgaaaaagcc aaaccagtgg taattgccga aacaaccgca acgttggcga
     5881 ataaagagaa aacaggaact tggaaaattt tgcataaatt aaccgcagaa caagttttgg
     5941 ataaaaccat cgtcttattc aactatgtgt atgaaaacaa gaaaccctat gaagcaggtg
     6001 atgatccagt agcgaaagat gctagcttga acaatcaagc ccaaactgtc aattgtacgg
     6061 tggaacgcca tgtttccatc caaacaaaag cccacctaga agatggttcg caaaccttta
     6121 ctcatgggga tgtggtggat atgttcgatg atgtgtcgat tacccatgat gtactggatg
     6181 gctcaaaaga agcttttgaa acaattctgt atgcattact tccggataat acgaccaaag
     6241 aaatttggaa atctggcaaa attgattatg aagtgaatga caaagaattc actaaaaccg
     6301 tacttgcgga aaaagtggac acaagtaaat atccagaagg tacaagtttt accttcaaag
     6361 aaattaacta tggcaaagac ggaaacatca atgggaaaca caatgaggat ctaaaagaaa
     6421 aaactcaaac tttaacacct aaaaaagttc cgacaacacc aagtgcacca gaacaaccgg
     6481 aaataccaac tgttccaagt gactctcaag aatctagtcc tacagtaaag acattcccac
     6541 aaacagggga gaaaaattct aatgttctgc tgtttattgg gtttaccttg atctttgcga
     6601 ctgctgggta ttatttctgg aatcgccgaa actaaggtga tgtgatgaaa caactaaata
     6661 ggaaaaacca acgtgcgcga ccgcctccta aaaaaagtgg tcgcgctatt tttgtatcca
     6721 aaactaaaaa tgaaaagagg aaaagaagat ggaattgaaa tttgttgtgc cagatatggc
     6781 cgaaaccttt ggaaagataa ggtatgccgg cgaaggcgaa gttttaactg aaggatatgg
     6841 gcggaatact acagtaattg gtcgtagtta tcatttgtat tccagtaagc aacgagccga
     6901 tgatattgaa gtggtggtag ctgcggaagc cggcgaaaag gattttgatc aagatcaacc
     6961 actaaaagcc gtgaatcccc atttggttgc caaaggctat gagattgaga atcgtgggtt
     7021 taccgactac gtgttgtatg tcgatgattt agtgaaagca taggaggaaa agaagatgag
     7081 attaacagaa ggtattgttg tagattcagg actaacgttt gggaaattac gattttccgc
     7141 attacgccga gaagtacgga agcaaaatga ggatggaacg gttagtaacg aggtaaaaga
     7201 acggacttat aatttgaaat cctctgcgca aggtcgaatg atccaagtta gtatcccagc
     7261 aaatgtaccc ttacgcgagt ttgcctatga cgcagaggta gagttggtca atccaatcat
     7321 ggatacggtc gccaattatg ttttccgaga aggaactact gtcaattggt tcattaaggc
     7381 cgatgattta gtcttgaaac gacaaccaga tcagggaaat tctacaaacc aaaatgaagg
     7441 aaagaaatag gtgaagcgta tggaaattaa tgttgaacat attttagatt gtctcgatca
     7501 atatggaaaa ggtgagctaa cggaggaaca actcactaaa gcattaacct atgatgaaaa
     7561 aatgtttctg attatgcatc aagggttact ggaagtaggt aacgatgccg aagaagattt
     7621 tgatgtactg aattggttag gggaagaaga gtccttcttt atggttatcg aagtaaatga
     7681 aagtctatgt cgagaagccg aaaccgtatt ggaagaaatt ggtgtggaaa tgccggatgc
     7741 cattgaagtt tttttaaagc aactagtgga aacgaaacaa ctccctatag cagtaaatga
     7801 ctagcataac tgcttgaaat tggatcaatg aaatcctatg aagctttttt cgattggagg
     7861 tggaaaccat aaaaatgtac aaagggcatc gtatacgggc aggagatcag cacttggttt
     7921 atcactttgt tcttggctgg ctactcgctc tgttcatcgg ttggatgagc gtcttttatt
     7981 ttcaagagct tagacaattt gatatttcta agctatcact ttctactata gaaatcgttc
     8041 gttctataaa agatttaatc tatttgctag gaagtctcgt tctttcagga agcacgatgt
     8101 tgctttatat acactttttt caggatcatt ggcgcagttt gtggcatcga caaaagctag
     8161 cccggatgat tctagaaaat cattggtacg aagtaaaaca aactcagagt gaaggatttt
     8221 tcaaagacct caatagtagt cgaaccaaag agacaatcag ttacttcccc aaaatctatt
     8281 accgtatgaa ggatggttta ctttctattc gcgttcaaat ttcactggga aaatatcaag
     8341 atcagctttt aaagctggaa aagaagttag aaagtggtct atattgtgaa ctagtagaaa
     8401 aggaactcaa agactcctat gtggagtaca ctttactgta tgatataatt gccaatcgaa
     8461 ttgggataga cgaagtagtg gcagaaagtg gggctttgcg attgatgaaa aatcaagtat
     8521 gggcttatga ttctttacct catatgttaa tcgctggcgg cacaggtggt gggaagactt
     8581 actttttact cactatcatc gaggctttat taaaatctga tgccgagctt tttgttcttg
     8641 atcccaaaaa tgcggactta gccgatttag gtacggtaat gcctcatgtc tattcccaaa
     8701 aggaggaaat ttctgcttgt gtggaagatt tctatgagcg catgatgact cgtagcaagg
     8761 caatgaaaga aatgcccaac tacaaaacag gagagaatta tgcgtttctt ggacttccac
     8821 caaacttttt aatctttgat gaatacgtgg tttatatgga aatgttaacg acgaaggaaa
     8881 gtgcggtgat tttgaataag ctcaaacaaa tcgtgatgtt aggtcgtcaa tctggtttct
     8941 ttctgattct agcttgtcaa agaccggatg cgaaatattt aggagacggg attcgcgatc
     9001 aatttaattt ccgggtggct ttgggtcgta tgagtgaact gggatattcc atgatgtttg
     9061 gcgaggttga taaaaaattc tttatgaagc gtatcaaagg tcgaggctat gtagatacgg
     9121 gagggagtgt gattagtgag ttttatacgc cacttgtacc aaaaggatat gatttcttaa
     9181 gggaaattag cgacattggt ggattaaacg ttaatacgga aggataaaat aatagtatgt
     9241 agcctaggag tgtcaagaat cctgggcttt ttttacgagg tgatttatga catttttaga
     9301 tttattcgct gggattggtg gcttttgctt aggtatggaa caagcgggtc accagtgtat
     9361 cggcttttgt gaaattgatg attttgctcg ccagagttat aaggcaatcc atgatacaag
     9421 taaggaggtg gaaatgcatg acatcacaag tgtatcagac gagtttattc aatctctcgg
     9481 accagtggat atcctttgcg gtggatttcc gtgccaagct ttttcaattg cgggaaagcg
     9541 gcaaggattt tccgatactc gaggtacttt attctttgaa atcgctcggt tcgccgctat
     9601 tctccaacct aagtttttat tccttgagaa cgtccgggga ttactcaatc acgaaggagg
     9661 ggctacgttc gagacgatcc tccgaacgct ggatggattg gggtatgatg tggaatggca
     9721 agtgcttaac tcaaaggcct acgttcccca aaaccgtgag cggatcttcc ttatcggaca
     9781 ttctcgagac gcatgtaccg aacaagtatt tcctatcatt ggatcgtctc caacatctga
     9841 tcaaaacatc agaaacttat taaatatcaa cccttccaat cgaggaatgg ggggacaagt
     9901 ctatgggtca gatgacgtag cgcctacctt gaccggtgat gaaggaatca aaatcgcatt
     9961 gccggtagat gatggaattt ctgtagcggg tatgttactg ggaaattttg aacaaggcaa
    10021 tcgggtttat gagataactg gaacagcgcc tactttgtca acgaaacaag gcggaacgaa
    10081 gatcatgctt cggaaaaacg aaacagaata tcaagaggtg aagccaggga acagtgtgaa
    10141 cctggctttt cctaattcca caagtcgtcg aggccgtctg ggaaaacaaa gtgtgcatac
    10201 cttattaaca ggagaccaac aagcagtcgt cacggatcag tatcaaattc gaaagttaac
    10261 acctagggag tgctggcggc ttcagggctt tccggactgg gcttttgatc gagcttctca
    10321 agtcaattca gatagtcagt tgtataagca ggctggaaat tctgtaacag ttccggtcat
    10381 ttttgatatt gctagaagat taaaggaggt aaaaacagat gatttatgat gagttgattg
    10441 gggaatctac tgggtgattg gcaagattca gtcagatccg gaattggaag aagaactgta
    10501 ccggctcaat tttgatattc gcaaaaacgg ggtgaaagtc cctgatgatc cgtatgtaat
    10561 tgatgaggaa acggatgctc gaatggagct gaatcaagtc atcagtgaat tggaacgaat
    10621 tgcggacttt gctaaagaac ctgatatccg ccaatacttg tttgagataa aagcagagtt
    10681 ggaaattgag ggtattaccg cggagtaacg gccaaataaa ccactgatag gcactgaccg
    10741 cgggggattt gcgaagcaga aatcctccgt ggtgctgtgc ctgtttatgg acggcgttag
    10801 ccggccatga tgtctcaccc cccgtatcta acaggggggt acaaaaacac aaaaaataag
    10861 caagcaacga taaggaatgg ctgtcctatc aaggataata agcaatttgt gtagatgtta
    10921 actgatttga aaaagttaac accttaaatt tggaggtgag aacttggcac aaaggaattt
    10981 agattatcgg ctattaaaag accggcgtaa tgaatatggc gtttcacaaa ataaattagc
    11041 tacgacttgt ggacttagtc gcccgtactt aaatcagata gaaaatggtg gcgtaaccgc
    11101 atcgacaaaa accatgagga aaatttttga ccaactggaa agtttcaatc ccgagttacc
    11161 tttaacgtta ctgtttgact atgtaaggat tcgctttccc acaacggatg cgaggaaaat
    11221 cattcaagag attctccatt tgaaatttga ttatatgctc cacgaagatt acgcctttta
    11281 ctcctatcaa gaacaatatg ttatgggaga tattgtggtg atgttgtcac atgaagaaga
    11341 taaaggcgtc cttttagaat taaagggtcg tggttgtcgg cagtttgaaa cttttttact
    11401 cgcccaaaag cgtagctggt atgacttttt cgaagattgt ctaaaagccg gtggcgtgat
    11461 gaaacgctta gacctggcaa tcaatgatcg agttggcctg ttagatattc ctgatttaac
    11521 gaaaaaatgt cagaaggaag aatgtatctc cttgtttcgt accttcaaaa gctatcgttc
    11581 cggggaactg ttgaaacctg atgataaaga tggtatgggc aatactttgt atattggcag
    11641 tcttaagagt gaggtctatt tctgtttgta cgaaaaagac tatgagcaat atatcaagtt
    11701 agggattcct ttagaccaga ccgaaacgaa aaatcgtttt gaaatccgac tgaaaaatga
    11761 tcgagcttat catgcaattc aagatttgtt aaaaggtcgc agtattgaaa gtaccacatt
    11821 ttccattatt aaccggtact tgcgatttgc ggataaggtg gaaggcaaaa ggcgaactaa
    11881 ctggcccttg aatgaacaat gggggcgctt cattggacgg aatcagaagg aaattcaatt
    11941 aacttctgaa ccgaagcctt ataccattga acgaacgttg aactggcttg gacgacaagt
    12001 cgcccctacg tggaagatgg ccaaggagtt ggatcggttg aatcagacaa cgtacattca
    12061 ggatatggta aataatactc gactatcaga ccggcacaaa aagattttgg agcaacaaag
    12121 tatggcaatt gaaaatttga ttatatgaaa agaggaatcg tgatggaaat tgtgaaagat
    12181 attttattgg tgtttggtgg cagtatgctt ggtgttactg tgatgtgctt gatgcatgca
    12241 agtgcagcgg cggaccgagc aatggaaaag aaaggaaagt gatgaaatga atttcggtca
    12301 aaattt
//
LOCUS       DARBDN010000077        12237 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000077 DARBDN010000000
VERSION     DARBDN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.078"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            507..1070
                     /locus_tag="SCH06_002103"
     CDS             507..1070
                     /locus_tag="SCH06_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078650.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1131..1496)
                     /locus_tag="SCH06_002104"
     CDS             complement(1131..1496)
                     /locus_tag="SCH06_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078651.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1572..1817)
                     /locus_tag="SCH06_002105"
     CDS             complement(1572..1817)
                     /locus_tag="SCH06_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1078652.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1887..2141)
                     /locus_tag="SCH06_002106"
     CDS             complement(1887..2141)
                     /locus_tag="SCH06_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078653.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2305..2628)
                     /locus_tag="SCH06_002107"
     CDS             complement(2305..2628)
                     /locus_tag="SCH06_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078654.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2815..2888
                     /locus_tag="SCH06_002108"
     tRNA            2815..2888
                     /locus_tag="SCH06_002108"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2849..2851,aa:Ile,seq:cat)
     gene            complement(3273..3770)
                     /locus_tag="SCH06_002109"
     CDS             complement(3273..3770)
                     /locus_tag="SCH06_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEG1078655.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3810..4619)
                     /locus_tag="SCH06_002110"
     CDS             complement(3810..4619)
                     /locus_tag="SCH06_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEG1078656.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4953..5810
                     /locus_tag="SCH06_002111"
     CDS             4953..5810
                     /locus_tag="SCH06_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEG1078657.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5803..6705
                     /locus_tag="SCH06_002112"
     CDS             5803..6705
                     /locus_tag="SCH06_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEG1078658.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6738..7088
                     /locus_tag="SCH06_002113"
     CDS             6738..7088
                     /locus_tag="SCH06_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEG1078659.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7137..8060
                     /locus_tag="SCH06_002114"
     CDS             7137..8060
                     /locus_tag="SCH06_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEG1078660.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8138..9031
                     /locus_tag="SCH06_002115"
     CDS             8138..9031
                     /locus_tag="SCH06_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1078661.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9069..9632
                     /gene="amaP"
                     /locus_tag="SCH06_002116"
     CDS             9069..9632
                     /gene="amaP"
                     /locus_tag="SCH06_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEG1078662.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9646..9834
                     /locus_tag="SCH06_002117"
     CDS             9646..9834
                     /locus_tag="SCH06_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEG1078663.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9847..10749
                     /locus_tag="SCH06_002118"
     CDS             9847..10749
                     /locus_tag="SCH06_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEG1078664.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10781..11023
                     /locus_tag="SCH06_002119"
     CDS             10781..11023
                     /locus_tag="SCH06_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEG1078665.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11279..11650)
                     /locus_tag="SCH06_002120"
     CDS             complement(11279..11650)
                     /locus_tag="SCH06_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078666.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4366 a         2051 c         2309 g         3511 t
ORIGIN      
        1 cattggtcgt tgaatgggct gaatagtagt gtataaaaca attttgtgga gcgtgaagct
       61 tttatggtag aggaaaatac gaataaagtg atgttgataa aaagattcct atcttgaata
      121 tgaatcgaga tgtcttgaaa atgaatgagt ttgaccaatc attatcctat cgaaatttac
      181 agtttcgttc gattggtctg tcaattaatg aaaaagtaaa aaagaatatg ttctaggaag
      241 agggcggcac atctaaattt ttaagtaacg gacagttcaa atatcaagca ttgaaagagg
      301 ctatcctact gtttgaagga atacgaatat ataaaaacga caaagaggaa aaagtagttc
      361 attaaatccc ttcaagtgat gaaagaatga gatctaataa aacctgatct ttcatctgtt
      421 tttttaataa cgtaataatt tttttatttt ttgtgctttc gccgttattg tagagtgatt
      481 tagcattctt atttttaaaa ataactgtgt tatatattaa aaaaggcata atagttataa
      541 gcttttttaa agaatattta gaaattatta attttcgtct gaaaacaaaa aaagaaagcg
      601 ttattatttt agtctatttt caggggggga accttatgat aaaaaaacta tttttactat
      661 caatattaac gctagcaatg gcaggttgtt ctgactctgg cttagcaact gaactgatca
      721 caaaatcaac tgaagccacg acagaggagt taaaatgtgg aaacgatcac agtgactaca
      781 gaggcttaaa tcgacgatgc atgggaatat taggcagaag caattgtaag catcgatgta
      841 gtaatcgaag aaggtgtaga agaagcaaca gaaaaatcaa aagaaagatc aaaagaagca
      901 atctgtgctg tgcatcgtat acagacgtcg aagatgcggt acttttaaac cacgtcagga
      961 gatgttcatt tatgtctagg gaagttggcg atgaaccaaa actagagtac gcttttagtt
     1021 ttgcacgtga ggatgaagat aaccctaaaa cttacgacat tttagcttga tctaagatgg
     1081 ttaaagcttt ttaatgaagt aagaggagat agaaggcttt tctagttata ttaggtaaga
     1141 taaattcctt tttgctccaa atttgctaaa cattctgcta gataaacttc atcgtgttcc
     1201 ggataaatcg gcacgttgcg ctctacagta ggtaaatcaa aaaatgcttc gcatgatttg
     1261 ccacgataca taggattttt ccactctggt gctgggctgt aaccacgttt ttccatttca
     1321 tccatgacaa gctgatgata ttggaataat ctataaggag aatagtgaaa aacataatcc
     1381 acagtagcat gtttctttcc ccagccattt cctcttaatg cacagcattc ccgatgttgt
     1441 cctaaaagct gttgacgagg aagctttgaa atcaattttt catgccataa tcgcatagaa
     1501 atgtctcctt tatatataga ttgttaacct tagacgttaa atgaaaaaac cagcaccaag
     1561 gctggaaaaa atcacttcag tttgcttgct gtttctgagc gaccaattag gtaatcaacg
     1621 gaaatatcgt aaaagtcagc gatatagatt aattcaatga tgcttggaat ttcttctcct
     1681 tcttcgtact tacgatattt gaataaagga atacttaacg cgctagaaac agctacttga
     1741 gataaagatc ggccagttct taagaaattc agacgacaac gtaaagtatc cagtaaaata
     1801 gcttcttcga tactcattta atcacctttc attatagtag aatagttata atgactatag
     1861 aaagctacac atgcaatcaa tagtactcaa tgttttttat ttaaacgtat caaataaaga
     1921 atgacgatca ataaagacaa aaccagtcct gataattctt ctataaaaac actatcgggt
     1981 tcaaagtagt tgtaattaaa aactttccac ataaagtaga tagccggaag agtcaaaata
     2041 gctaaataaa accgttcttt gttccaattc ataagataaa caatacttgc gaccagtgcg
     2101 accgcaggca cccaaaacaa aactctcacc aacgtaatca tgtaacggac tcctcaacga
     2161 ttcatataat aaaagataac atgttattgc atacatcaca aatgaaatgc taggaaaata
     2221 aaagaagaat agatcaatga aaaatgaaaa agcagaacag ttttctgctg ataagcagga
     2281 actgttccgc tgaatgtgtc ttatctatcg agaaaaaatc aatggattga tatctaagta
     2341 attcaataca tataaaaaga ggacgatcgc attcactaaa aaggaaagaa tgatgatccc
     2401 atagcgaatg gaaacatatt taacaaatac ttttgtttga atacgggcat atctttttcc
     2461 tttatagctg agcatcatga caagaagcaa aagggtaatc acaccttgaa aaatcattcc
     2521 aataaacaga attcctgagg tttgataatt taattggaga aaataagctg ctgccgcaac
     2581 taaatcgaat aaaatcgcaa taaatggcaa aataatcact cctaacattg agaataaata
     2641 aaagaataac attttttcta aaataagcaa ataaaaatta aagtaacaaa atagttatga
     2701 cacaagtaaa agaaataaga ataacaatat tattttactt atattttgaa acttgtgaga
     2761 gtttgtcatt cgtgctatag ttgaaaagta acaaaaataa attttattta tgatgtacct
     2821 ttagctcagt tggttagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac
     2881 aaggtacata agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta
     2941 aaaacagctt cttatgtttt tacttggctg ttcttattac tgcagatgca agcttttgaa
     3001 taccgtttaa ggaagaggtt gtgaaatcag cgttttgacc tgagtattag cttaacaaac
     3061 ggaaaaatag ttcctcatat tttgccgttt gttaagctaa taccgagggt cagctgattg
     3121 aacaccattt aagaaagagg tcgtgagcct gccgtttcac tctgtgtcat aaaaaagcca
     3181 atctactttg atagaaaaag cacgtaggac taaaacagtt ctgcgtgctt tttttattgt
     3241 gtgttaaata tcgtaaatga agatagatat ttttatgatt cgacgataga gacgttgaaa
     3301 tctttcaaca gctctaaagc ggattctccg tgttttctac tggagactaa cattggatca
     3361 acaaaaaagt ctgcttcagg aaaagcactc tgcaggccta tcagattaga gagtacacac
     3421 aagtttgttt caatcccgac tacttcgatc tctttttgtt cttctttgct ttcaaataaa
     3481 gtttcctgga tttcagctaa agtttcaggt ggaatcgtaa agtaatactt tttaatcact
     3541 cgttcatttt cttgtggaga aagaagaggg atcaattgca aatcttctcg ttcttcttct
     3601 ttgtccttca gttcaactgg tatatcccgt gtgaagagaa tatattcatt attttggcgt
     3661 gctttagcta atctttgagc aatacgttct gccaattgat ctgactctgg aatataaaat
     3721 tcgctgtttg gatcaagaat atgattttgc atatcaataa taactaacat tttctttcct
     3781 cctacattca tatcgtcatt ttattctttt taatagaagt tttttaaaat ataagcaaca
     3841 ccagcttctt cattcgtcag tgttacttgg tttgcaattt cttttacttg tcgctgtgca
     3901 ttccccatcg caatactcaa cccgctgtaa ttcaacatag caatgtcgtt ttcttgatcg
     3961 ccaaaagcca tgatgtcact cgattcgatt ccaaggtaat ccgccagaaa aacaagtgaa
     4021 tgagctttag tgatacctgt aggcgtgatt tctaagaaat gcggatcaga gaatactgat
     4081 tggataccat ctgcttgcag atctctttgt agcttctgta gtttttcttc actcttatct
     4141 gttaatgcta atttaagata gctaagagaa ggatcttcca acatatttaa aatttgatca
     4201 aaagaatggt tctgtaaatt gaaatgttca taataagggt catctttgac tagatttgat
     4261 tcatcgaatg tcagctgatc atcttgggtt tctcggctag caatgatgga tattttcgct
     4321 tcttgagcat agaagaaggc ttttctcagt gtatcgctat ctatttttga acgtctgaga
     4381 actttcgcca tttttccatc cttcatttca gcaatcagtg aaccattgga agaaatcaaa
     4441 tagccaccga ttcctaattc ggaaaaaata tctttagcag aaatgctgtt ccttccggta
     4501 gcgacggtta cgattccgcc attttcatca aatttccgaa gtgcttggat attttcttct
     4561 ggtatctttc catttcgatc aagcaaggta ccgtctaaat caatcgctgc tagtttcatt
     4621 ttatcttcct actttctttt tacatatcta ttttcctgtt accttaagat taaatgagaa
     4681 tttaaaaaaa tgaaactaac ttgctttgtc attatgaatt ttttcaaaaa acattcttaa
     4741 gaaaaaggtg gctatatata gtagtttttg gtcaatacct ttgaataaaa agccatgaaa
     4801 aacgaatagt tagcgcttac cgatgcgttt tgtgataaaa aaattttaaa atattcaatg
     4861 aaaacaaagc atatattttg ctttaaaacc aaatgaggaa tattctagat gtagaacagg
     4921 ttagaaaaag attagaaaaa ggagtgattt tgatggagaa gagatacggc gtagttcctg
     4981 tggtaactgc ttcagacgaa aattatgctc cttacttgag cgtgatgatc gcaactgcat
     5041 tagaaaattg caataaaaca agacgcataa aattttatgt gattgacgat ggtctatcag
     5101 aatatagtaa agaaggattg gaagaaacgg taaataaata ttcaagtaat gcaagtatcc
     5161 aattcctgac agtggaaaaa gatatctacg aagacttcct agtcagtgac catatcacaa
     5221 ctaccgctta cttaagaatt tctttaccaa acttattagc taaagaggat tataagaaag
     5281 tcctttactt agattcagat gtgttagtac tagacgatat cgtaaaacta tatgatgagc
     5341 cgttaaatgg aaaaacaatc ggcgctatta tcgatccagg ccaagtgaaa gctttggaaa
     5401 gattaggaat cgattccgat gacttgtact tcaattcagg agtgatggtg attgacattg
     5461 atcaatggaa taaaaaagaa attacagaaa aaactatcca ttacctcagt gaaaatggcg
     5521 atcgaatcat ctatcacgac caagatgctt tgaatgctgt actttatgaa gattgggaac
     5581 aacttcatcc aaaatggaac atgcagactt cgctgatttt tgaacgtcat ccagcaccaa
     5641 atgaaaaata tgaacgtcag tataaagaag gaaatgaaaa accttcgatc gttcacttta
     5701 caggacatga taaaccttgg aatacgttga aagatcatcc gtataccaat ttatacttaa
     5761 aaaaattagc acacagtact ctaacgaaag taggcgagat caatgaataa aaaagaaata
     5821 gcagtagtcg caagttgtaa cacaaaattc gtaccacatt tagctgcatt atttgtctca
     5881 gtattagata attgcaaccc gtctaaattt gttcggttct atgtgattga cgatgatatc
     5941 gattttgaaa gtaaacagct tttacgcttc tcagtgaaaa acgcacgaat gaactcagat
     6001 gtggaattct tgaaaatcaa taaagaattc tttacaaatg tggtaatcag cgatcgtatt
     6061 ccagaaacag cttattatcg tattgcgatt ccggaattgt tccgcggcac agaagttgaa
     6121 cgtatcttat atatggattg cgacatgatc gctttacaag atatctctaa attatggcgt
     6181 cttgacttcg gtgattcaat cgtagcagct gttgaagacg ctgggttcca tcaacgactg
     6241 gaaaaaatga aaatttcagc taaatcaatg cgttatttca actcaggttt gatgctgatc
     6301 aatgtgaaaa aatggttaga tgaaaatatt acgcaaaaag tattagattt catcgaacat
     6361 aatccagaaa aattacgatt ccatgaccaa gatgcattaa atgctatctt acatgaccgt
     6421 tggttaccac ttcatccgcg ttggaatgca caaggctata tcatggcaaa agcaaaaaaa
     6481 catccaacag cagcaggtga acgtgaatac gaagaaactc gcaacaatcc ttacattatc
     6541 catttttcag gacatgtgaa accgtggagc aaggattttg aagggccaac gaagaaatat
     6601 tacgaaaaat atgcagggat gacggctttc cgttgtgtag ctaaattccc taaatatcca
     6661 aaatatgcaa aagttcaacc aaaaacagat gtagttgtta aataatagaa gacaacaact
     6721 gaagaggggg agtaggaatg gaaattacaa tgtctaaaaa tgcagtagag acgttaattg
     6781 aaaaggttgg ggaaaataca aaaatcgcac tcgcgcttat caatgattcc gatccatttc
     6841 taagggacaa aggtgctttt gcaaaaggca gcttttttca aatcattcct tttgtttcgg
     6901 aatttggaga atatgcgact aaaatcgagc atccattatt ggacatctat acatctaaat
     6961 tagagcaaaa ttatttcggt aaacgattga acatggactt caacaaacag cttgacagct
     7021 tttcattaga aaatgaaatc gcagtactcg attataatat caaattaaag aactgcttct
     7081 tcagctaata gtttcgagaa agtccaaaaa ggaggtatac attgagatac tactttgtgg
     7141 atgaagaaaa gaatgtaata gaaacagatg aaaaaaaata taattggctc gtacttgata
     7201 gtgcaaagcc cgaagagatt gagcaagcaa tcgaagaatt cgagcttcct gatgatattt
     7261 tcgtaggaac cgaatatccg gaagaagttt ctcggatgga gcgcctttat gagacgaaac
     7321 tagagcatcc attttctttg gtagtgatta atctagatca gtcagataat cgtatcgaaa
     7381 aaaaattaac gccaatatct tttgtacttt ccgataatct cttgattact tgtatcgata
     7441 gaaaaaccga atttgtggat cggctgctga caaagcatgg aaatcattta aactcgtttg
     7501 aaaagatcat cacgtataca ttattagata tttacaccca ttacgtgaaa gaactaagag
     7561 agatgaaaaa gcgaattgac gctttggata aagcagctcg taaaacaacg gaaaatgaag
     7621 aactgtataa acaggcagat cttgaaagag acatcgtata tatcgatcat accttaagag
     7681 atcaacggga aacaatggat caattatgga attctgaaac tttcatcaaa cgtttagacg
     7741 atgaacagct actctatgat gtccatttga gacagcgaca aacagaaaaa atgatcgaga
     7801 tctatcgaga tttattagag agtattggtg atctattcaa cgggatgatg gacaataatc
     7861 taaatcatat catgaaatat ctagattcag ctgcattaat catttccgtt ccggcgttgt
     7921 tcgcagggat ttggggaatg aatacaggag gattaccggg taaaagttct gctctaggct
     7981 ttatactcgt agtctttggc tctttgatag cagcagtagt tttaggttac catttatacc
     8041 ggaaagatta tacaaattaa agaatctatt taaaacaggt atcaaacaaa gaaatttgtt
     8101 ttggcaatac aatttaaaaa ctaggaggaa tacagcaatg acagaaccaa aattaatcga
     8161 cccgcgaaac ttgtaccata cggagaaatt tcctaaacaa gatcaggata caccagcttt
     8221 acagcagaat atgattcctg ttcctgattg tggagaagaa tcctatgaag gcaataatca
     8281 actagaaaac cgccgtgtac taatcactgg tggagattca gggatcggtc gtgcagcagc
     8341 gattgcattt gctagagaag gggcagatat cgctcttcaa ttcttcccag gagaagaaaa
     8401 agatgcagag gaagtagcaa aatacgtgaa agatgcagga cgtaagattg tcttactacc
     8461 ttttgatctt cgtgacgaac aagcacctaa agaaatcata gataaagccg tgagtgaact
     8521 tggcgggcta gatacgatgg tactaaacgc aggacagcaa atttcttgtc agtctattgc
     8581 tgagttacca cttgagcaag tcaaagacac atttatgata aacatcatcg ctatgtttgc
     8641 tttagtgaaa gaagctgttc cgcatatccc agcaggagga gcaatcgtaa caacaacttc
     8701 tgttcaagca ttcaatccaa gcgaacattt attagattac gcagcaacaa aagcttcaat
     8761 cgctaacttt acgatcggtt tagcaaaaca gcttgcacct aaaggaatcc gtgtaaatgg
     8821 tgtagcacct ggtccaatct ggacaccatt acaactagac gaaggacaac cttctgattc
     8881 gatccctgaa tttggtcagc aaagtttact agaacgtgca ggtcagccag gagaattagc
     8941 accagtttat gttttcttag catcgaataa agcaagttat gttacagccc aaatttacgg
     9001 agtaactggt ggagaagcga tcaacttata agaagttgat cgtttcaccc ctatgaggag
     9061 gtgcgaaaat gaataaaggt gtaaaaacga tcggagtgat cggaacatta cttttgctat
     9121 ctgtgctttt gtttgcgata ctattaagtg caacctatcc attgcctttt cagctagaga
     9181 agtttcgatt cttttccatc actaattcat acgtgcaaca atatgtattt tggcttgccg
     9241 ttgcatttgc tattttgaca attatcacgt tacttgtttt cctgttttat ccaaaaacaa
     9301 tcggaaactt tctactgaaa catggtgatg gggagttgac gttggataaa aaagcaattg
     9361 aaggaatggt tcgttctcac ttgcatgaag atgaattcat ccattcacca aaagtaaatg
     9421 tcaaagcaac gaaaaacaag atcgccgtca atgtaaaagg ggagttgaaa cgaacttcag
     9481 cactcattgg taaaacagga acattgatga aagaaatcga aaatgaagta caacacatat
     9541 tgggaacaaa agagccagtg aaagtatcgg tgaaatacac aggctttgaa gaaccagcta
     9601 aacgaagcaa tgaccgcaaa cgagtagaat agggggggac caaaaatgaa agaactattt
     9661 tcgacataca agctccctat catctttggg gtacttggat tgatattagc cgttttatgg
     9721 atcaccgtgg gctttttcaa gaccttattg atcttgatca tggcagcgat cggcgtcgct
     9781 atcggttttt atctgaaaca aacgaaaatc ttagatcact attttaaatc ttaggaggaa
     9841 acatccatga ataacaataa caaaaataat aacaataaaa tgaacaacca aaaaccagtg
     9901 tctgcacatc cagacccaac gacaccaaac caatcaaatg gtgtgaacga tgaaaagaac
     9961 aaaacagcac cagtatctgc acatccagat ccagtagtcc ctaacgttca acaaggagta
    10021 gaagagaaga aacatgatgc agaaaagcat gcacctcatc atccaggaac tccagaatct
    10081 aaagttccag aacaacatga tgcaatcgat ccttctaaac ctgtggaaga gcaaaaacat
    10141 ccttctgacc atgcgaaagc acaagaaaaa cttagttctg accacacaaa cggacaagga
    10201 aaacttggtt ctgatcatac aaataaccaa ggaaagcatg attctgaaca ggaagattca
    10261 atgcgcggtg agctgaatta tgaagataaa gttgtgcaaa aaatcatcgg aatcgcaatt
    10321 gaacaagtag acggtttatt atctgcaaac ggtggtttct tctctaatgt ggcaggaaaa
    10381 cttgtgaata cagataatgt aacggctggg atcgaaacag aagtcggtaa aaaacaagta
    10441 gcagttgata tggatgtcat tgtggaatat ggcaaagata tcgaaaaaat ctttgaagaa
    10501 atgcaagaag taatcggcaa agaagtaaaa aatatgacac atttagaagt gatcgaagtc
    10561 aacgctaacg tagtggacat caaaacaaaa gaagaatttg aaaaagatca agaaacggtg
    10621 caagacaaag taactgacgc agcgaaaaaa accggtgaat ttgcttcgaa tcaaacagat
    10681 aaagtaaaat cagcagctgg aagcggcgca caaaaagtaa aagaaaatac agaaccacgg
    10741 gttcagtaat aaggaagtaa aacattagga ggaacgaaac atgggattta tttggtcact
    10801 tatcgtcgga ggaattatcg gagcaattgc aggagcaatc acgaataaag gttcttcgat
    10861 ggggattatt gcaaatgtcg tagcaggttt agttggatca gcacttggtc aagcattatt
    10921 aggttcttgg ggaccaagta ttgcaggaat ggcaatcgtg ccatcattga ttggtgccat
    10981 cattttagta ctaatcgtat cattctttgc tcgaaaactg taaaaagact tttaaaaaga
    11041 ggtcgtgaaa aagctgttct tcatcaagta ataagaacag ccaaacaaaa atagcttctc
    11101 atatttttca tttggttggg catattatcg aagatgcaag cttttgaaca ctgtttatac
    11161 ggaataagag gctgtgacaa gacttttgtc acagcctctt atttatgcgg gcaaattccc
    11221 aattagattt ttaaaagttt ttccttaaat gtgtctttat tgatacagag aagcttcttt
    11281 aataaaacaa tgcctcccta aattttcttg agataggaaa ggtgaacata caaaataata
    11341 cgaccacttt gaaaacccag atgatccaca aatggatcgt atgatactga tgaagtaaaa
    11401 agcaatggat cagaaactca aagagattga aaaagacaag gaagaaataa tatctctttt
    11461 ttactcttgt ctgttttagc caataatagc tcgtaaagta atctagacaa acaaatagaa
    11521 gtaaacaaag tttcgtaaga gcagcaatcg tatcatgttg ctctgctaga cgattgacga
    11581 gcaggaaaaa tgttggtaat ggaatataga tcacgagtaa tgaaagaaaa aagtaaacaa
    11641 taaatggcat actattcctc ctaattgtgt gagttcgccc tcattttaaa ataacgatat
    11701 ttgtttgtga agctttttcg tgtcgtaaca aatgttatct aatgtatttt taaataaata
    11761 atcattatta tcaaaataat gttaaaaata aaaaagaatt gtccatcact gttattcaaa
    11821 tcattttatc aaaactacat agtaaatgtt aaaaagcaac atgacataat atatagaagg
    11881 ctttacagta tatatgggag cttactaaaa aagaatggag taagagttaa cacaatgggc
    11941 cattagctga agttttaagc acttcaaggt atgaaacaga atggcctgta atactacatg
    12001 attatttaga ctgctcaaac tgctatcagt ctggtggaat gaataaagta ttatactaaa
    12061 agcagatcca actacaacgt aacaggaaac cagttgtatc aggaaaagtg atagtacatg
    12121 gagaagaaaa ggcccccttt gtatgagtca gtacatatct tatttataga taaaacggta
    12181 ttcaatcgaa ataaaaaatc tgaataatag acgtaaataa cttctaaaag tctcaca
//
LOCUS       DARBDN010000078        12182 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000078 DARBDN010000000
VERSION     DARBDN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.079"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            257..532
                     /locus_tag="SCH06_002121"
     CDS             257..532
                     /locus_tag="SCH06_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078667.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2617
                     /locus_tag="SCH06_002122"
     CDS             545..2617
                     /locus_tag="SCH06_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HEG1078668.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            2782..4668
                     /locus_tag="SCH06_002123"
     CDS             2782..4668
                     /locus_tag="SCH06_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEG1078669.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4680..5627
                     /locus_tag="SCH06_002124"
     CDS             4680..5627
                     /locus_tag="SCH06_002124"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEG1078670.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5647..6174
                     /locus_tag="SCH06_002125"
     CDS             5647..6174
                     /locus_tag="SCH06_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEG1078671.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6237..6890)
                     /locus_tag="SCH06_002126"
     CDS             complement(6237..6890)
                     /locus_tag="SCH06_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEG1078672.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7022..7864
                     /locus_tag="SCH06_002127"
     CDS             7022..7864
                     /locus_tag="SCH06_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEG1078673.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8022..8918
                     /locus_tag="SCH06_002128"
     CDS             8022..8918
                     /locus_tag="SCH06_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEG1078674.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8921..9634
                     /locus_tag="SCH06_002129"
     CDS             8921..9634
                     /locus_tag="SCH06_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEG1078675.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9654..10172
                     /gene="msrA"
                     /locus_tag="SCH06_002130"
     CDS             9654..10172
                     /gene="msrA"
                     /locus_tag="SCH06_002130"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEG1078676.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10169..10396
                     /locus_tag="SCH06_002131"
     CDS             10169..10396
                     /locus_tag="SCH06_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEG1078677.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10548..11099
                     /gene="lepB"
                     /locus_tag="SCH06_002132"
     CDS             10548..11099
                     /gene="lepB"
                     /locus_tag="SCH06_002132"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEG1078678.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11182..11682)
                     /locus_tag="SCH06_002133"
     CDS             complement(11182..11682)
                     /locus_tag="SCH06_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEG1078679.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11961..12182)
                     /locus_tag="SCH06_002134"
     CDS             complement(11961..12182)
                     /locus_tag="SCH06_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEG1078680.1"
                     /translation="MKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHEV
                     DMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         4231 a         2075 c         2459 g         3417 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaacgagt ccaataaaat aaaaaggtaa aaattttcaa
     2641 gttttataaa aaacaaaaca tatcagaaca ggatcgaatc ggtcctgttc tttttttgag
     2701 aacacaaaaa gaacaaatac caaaaaaatt ttcctgaagt tcactatttt tatgatacaa
     2761 tatccaagat aaggagggaa catgttgaaa gaattaaaag taactgacct caaaaaaact
     2821 tatggtgaaa aagatttgtt tgaccagatt tcttttttgg tccacgaaaa agaccgtatc
     2881 gggttgattg ggacgaacgg gacgggtaaa acaagtctct taaatattat tgccggtatc
     2941 gatagcagcg acggtgatcg gcaaacagtg ttttatccaa ctgattaccg tattggttat
     3001 ctttctcaag cagctgaatt ttccgatgaa ttaactgttc tccaagcagt ctttcaagga
     3061 aacagcccct tgatccaaac tgttcgagca tatgaggaag cattgatcga actaggggaa
     3121 aacggagaag accctgatgt gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa
     3181 gaagatgctt ggactacaga taccaacgca aagattattt tgcaaaaatt aggaatcagt
     3241 gaattagata aaaaaatcag tactttatca ggtggtcaga aaaaacgagt tagtctggcg
     3301 caagtgttga ttgatgaacc cgatttacta ttactagacg aaccaacaaa ccatttagat
     3361 tatgaagcga tcgagtggtt ggaaaactat ttgaaacaat accgtggcgc actattgatg
     3421 gttacccacg atcgttattt tctagataga gtagcaaacc gaatcttcga actttcattt
     3481 ggaaaattat acgagtataa aggaaattat gaagcttacg tcttagaaaa agcagaacgt
     3541 gatcgtgtag aagtagaaca agaagaaaag cgcaagcggc tttataaaca ggaattagct
     3601 tggatgaggg ctggcgtaca ggcacgtggc accaagcagc aagcacggat caaccgtttc
     3661 gaagatctaa aggagaactt gtaccaagta aaccaagaag atgatttaga gctgaaccta
     3721 gcgacacaac gtttagggaa aaaagtactg gaaatcaaag atggcagtta ccgtataaat
     3781 gaccaaacac tgctagaaca tttagattta ttgattcaat ctcgggaaag actaggtatt
     3841 actggtaaaa atggtgcggg aaaatcgaca ttgcttaata ttctagctgg cagaattccc
     3901 ctggatagcg gtacaatgtc tatcggtgaa acggttcatc ttgcgtatta tacacaagaa
     3961 aatgaagaaa tggcaccaga taaacggatg attgcttact tacaagaagc tgctgaagaa
     4021 gcaaaaacag cagatggcag tcaaatcgga gtagcagaat tacttgaacg atttttattt
     4081 ccaagattta tgcatgggac actgataggc aaactttcag gcggagaaaa acgccggtta
     4141 tttttgttga aactgctgat tcagcaacct aatgttttat tattggatga accgaccaat
     4201 gatttggaca tagcaacatt gacgattttg gaagattatt ttagaagttt tccaggtgct
     4261 gtgatcactg tttcccatga ccgttatttc ttggacaagg tagcagataa gttattagta
     4321 ttccaaggaa acggaaaaca agaactttat tacggaaaca tgtccagtta tttactgaag
     4381 caaaaagaga cccagcagcc tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct
     4441 gctgaaaaga agaaattatc ttacatggaa caaaaagaat gggaaacgat tgaagatgag
     4501 attgcagaac ttgaagaaaa aatctcattg ctccaagaag agatgaatca tcaaggagat
     4561 aatttcactc gattacaaga attgcaaaac gacgtatctg aaacagaagc acaacttgaa
     4621 gaaaaaatgg cacggtggga atacttgagt gaatgggtag aagattagga ggaaaaagga
     4681 tggaacaagc gtatcttgac ttaggaagaa aattgttgga agaagggcat cgtaaagaag
     4741 acagaacagg cacaggcaca ttaagcttat tcggatacca aatgcggttt gatctgcaaa
     4801 aagggtttcc tttgttaaca acgaaacgag taccttttgg attgatcaaa agcgaattgc
     4861 tttggttttt aaaaggagat acgaatatcc gctatctatt acaaaataaa aaccatattt
     4921 gggatgaatg ggcatttgaa cgctacatca aaagtccaga ctataatgga ccagatatga
     4981 ctgattttgg ccatagatgt ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga
     5041 gcaagctttt ttgcgagaag atcctaaccg atgattcctt tgctgaaaca tacggcgatc
     5101 ttggacacat ctacggctat caatggcgtc actgggaaac aaaagacggt ggctttatcg
     5161 atcaaatcaa acaagtgatc gaagcaatca aaaagactcc tgattctaga agattgatcg
     5221 tttctgcatg gaatccggaa gatgttccta gcatggcttt gcctccttgt catacgatgt
     5281 ttcaatttta tgttcaagag ggacggctaa gctgccaatt gtatcaacgc agtggggatg
     5341 tgtttctagg cgttccgttc aacattgcaa gttatgcgtt gctgactcac ctaattgcac
     5401 atgaaacagg tttagcggtt ggcgaatttg ttcacacatt aggagatgct catctttata
     5461 tcaatcatat cgaacaaatg aaagaacaat tgagccgaga aatacgcgca tttccgactt
     5521 tagttttgaa tcaggaaaag cagtcagtat ttgattttga gatggaagat atccaattag
     5581 aaggatatga cccacatccg gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat
     5641 gagaaaatgt tagctgcaat ttgggcacag gatgaaaacg gattgattgg aaaagaagac
     5701 cgtcttcctt ggcgtttgcc aaatgatctg aaattcttca aacaaatgac agaagcaaat
     5761 acactagtga tgggacgaaa aacattcgaa gggatgggta gccgtccgtt gccgaatcgt
     5821 cagacgattg ttttgacgag agattcttcc tataaagcag aaggcgtgca tgtcatgcat
     5881 agtgtggaag acgtgcttgc tctggaaaaa gaaacagacg gtatcttttt catcgctgga
     5941 gggtcagctg tttatcaaga atttctgcca ttttgtacga tattataccg tacagtcatc
     6001 catcatgtat tcgatggaga tgcttatttt ccacctgttg actggtctga ttggtcactg
     6061 atcaatacta gtcaaggaga aatggatgaa aaaaatcgtt atccgcatca atttgaaacg
     6121 tatcagcgta atgagaatcc tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc
     6181 tatggataga ctagctgtta tttagagctg tcccatccat agctttattt tttttattaa
     6241 gtaaagaata aaacagagaa gtacataaaa cctgcaccta acataacaaa caaatgccaa
     6301 acaacatgca tatagcggat agaattcaag ctataaaaga atgcgcctat cgtgtaagaa
     6361 agcccgcctg ctaccatcaa aataacacca gtcattccaa gagagtgata aagaggaaca
     6421 gcagccacga cacagagcca ccccataaaa atatagatga tcgtagatac ttttgatact
     6481 ctctcccgtt tatgcaacgt caacgcttta tatataatgc caagaatcgc aaacaaccag
     6541 attaatacaa ataaagtcca acctagccat cctcggatac tcagcaaaca aaaaggagta
     6601 taacttcctg caatcaaaag aaaaatcgaa ctatgatcga atacttggaa cacctttttt
     6661 gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta aaaataaaag aatcatcatc
     6721 gatccataga tagcataaga gacaatatgg agggaggaat gcaagtgggc accttttact
     6781 aaaagaacca ctagtcccgc gatactcaat ccagtcccaa ttccatgggt gactgcatta
     6841 aacacttcat ttaatatttc atacgttcga ttaaatttcg ttttttccat gaaaacggct
     6901 cctttactag gtgtaattaa tgaaaaatca ttatttgtct gttatactaa aaatagaaat
     6961 tgtcttacat gtagtttaac atgaataagg catcttgtta aagaaagaga gagagaaaat
     7021 aatgacaaat gtaaaaatcg taacagattc ttcatgtacg atggaaaaaa atgtacgcga
     7081 tgctttaggc attcgtgtca tgccgctatc catcatgatc gacggaacag tatatcccga
     7141 tgatgaccaa ctagacggcg aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc
     7201 caaaacaagc caaccaccaa ttggagaatt catctcgatg tatgatgagc taggagaaga
     7261 cggcagtgaa gtgatttcga tccatatgac aaaaggcttg agtggaacag tagaagcagc
     7321 aagacaagcc agtaatctaa caaaaacgaa agtaacggtt atcgacagtg ataccactga
     7381 ccaaggatta tcttttcagg taattcgagc agctgaatta gcaaaagaag gtaaaacagt
     7441 agagaaaatc cttgaagaag tcaaaaaagt acaagacaat acaaaattat acatcggaat
     7501 atccacacta gataacttgg taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc
     7561 tagtgttttg aacatacgcg tggtgatgaa tttcgcccat tctgaattaa tccctgtaac
     7621 taaggggcga ggaaagaaaa cgttcgataa atggtttaat aatttgaaaa atgaactgaa
     7681 agaattgcca aatgtgcgac aaatcggtat ttcacatgcg gatgcaaaag aattggcgca
     7741 agaattcaaa gagggtttgc aagaattatt cccggacatg catatccctg tactgcatac
     7801 gaatccggtt atcgctacgc atactggtaa agacgcgttt gcaatcatgt attatgtaga
     7861 ttagtcgaaa agaggataag ccctcagcct gaaaggcttg cagcttattc tctttttctt
     7921 tataaaatta ggaaaataat tgttttcttt tttcataaag actacctttt tgataaaatt
     7981 tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac
     8041 atttgatcct cgttttgttc ccattattaa ttgcgatcat catctatgca ggtttagctg
     8101 cttctatacc gaaagctggc ccactaatga aaccagtaac tactgtgaga gaagatccaa
     8161 ataaaaaaga aaaacttcac tacatagcta tcggagattc gctgactgaa ggagtaggag
     8221 atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata
     8281 atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct
     8341 taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat caaaacagct gattttatca
     8401 cactgactgt tggcggtaat gatttgatga aagttatcca aaataattta ttcgggttaa
     8461 cggtcaattc ctttaaaaag ccactgaaaa actatcagga aaatgtcaca gaactattgg
     8521 aagaatttcg atccctcaat aaaaccgcac ctatttacat tttaggcatc tacaatccat
     8581 tttatttgaa ctttcctgag atcactgaca tgcagacaat tgttaacaat tggaacaaag
     8641 gaacagaaac ggtgacaaaa aaaatgccga actgctactt tatcccaatc aatgatttgc
     8701 tttatcaagg attgaatcag gaagtaggtg tcacagaaga aggaacagat caaacaacta
     8761 gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc
     8821 atccaaataa tttaggttat caattgatgg caaatgcagt gagagatcag ctgatcgaga
     8881 cacaaaacca atggttagag aaggaggatg atcaataaac atgaaaacaa gatctgacgt
     8941 atcttcaaac aaaacaaaga aaacaaatta ctggaaattc gccttcctta tccttcttgg
     9001 ggtagtactt ggttcgaccg tatttttagg cagccgtatt tttgctaatc gggaaccaga
     9061 actcccagaa ataccagctc ttacggaaag acaaggagat cctgtcttaa cgatcaattc
     9121 aaataaagaa aaagtcaatc aaatcatcag ctttttcctt agtgagtatc aaaaagatag
     9181 tgatattgaa tataaatttt atttggaaaa tgaagcacta ctcaatggta ctttcgaagt
     9241 actaggtttt cctatcgatt tctatttata ttttgatccg tatgtgatgg aaaacggaaa
     9301 tgtccaacta aaagctagaa gtctttctat cggaacattg agtttgccaa tcaaagatgt
     9361 gatgaatatg atcaagagaa actataaatt accagattgg atcgaagtca atacagatga
     9421 tctgactatc atgcttaggt tggatcaatt ccgaatgcaa aacgggatgt atattaaagc
     9481 agataaaatc gacttagtaa atgatgacat tcggtttagt ctatatttgc caaaagatac
     9541 ctctgatgct tcaaacaact caaataccaa caaaactagc accagcagta ctgaaagcaa
     9601 gacaaaagaa aataaaaaat catcggatga gtagtattag agggggaatc ataatggaac
     9661 gagcaatatt tgcaggaggc tgcttctggt gtatgatcca gcctttcgac acgcttcctg
     9721 gtatccatac agtgatgtca ggatatactg gagggcatgt accagatccg acttatgaac
     9781 aagtaaaaag ccaaacgact ggacatacag aagcagtgga gattatctat gatccaacat
     9841 tgatttcata tgaacaatta gtagaacttt actggcagca aactgatcca actgacgctt
     9901 tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt gatcttttat ttgacagaag
     9961 aacagcggat cattgctgaa aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac
    10021 agccaatcgt tacaaaaatc gaaccagccc aaccatttta tctagcagaa gaagaccatc
    10081 aagagtatta taaaaagcat cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct
    10141 ttatcgaaga aaattggagg aacgaagggt gaatcgaagc ttttttcatt atttaatgac
    10201 actgcgaggc ggtggcacac atgatgcttt atctgttttc gctacagaag ccggtaaaga
    10261 catccaattt cctaagcaca gctctagcta cgaagaaatt tctaattatc tggaactgaa
    10321 tgtcgactat ttgccgtcca tggatatctt tgacgaagca tgggaaaaat atttagaaaa
    10381 taatcatgac atataagaga tagttttgta ctttatgatc aaaaaagttt tttgtccaat
    10441 agcctaattg aaagaattat ttttatttca gctatctagt cgcatttttt tgatattttt
    10501 cttataataa agaaagaatg aaaaaaagag ggatggattg atagagattg acaaaaaaac
    10561 aacgctatat taatcgcttc tggcttgtat tcaaatactt acttgtttct gtattccttg
    10621 cgttcatgtt gcggggattt ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa
    10681 acgtgttgaa gcaaggtgat atggttgtga tggaaaaatt ttcggagatc agacgatttg
    10741 atattgttgt ttttcaatta gcagatggca cgatttatat caaacgagta atcggtcttc
    10801 caggagaaaa tgtcagctac caaaatgatc aattgaagat caatgggaaa gtagttaagg
    10861 aaccttatct aactaaaaac ctgaaatcag atcatgcaaa tgcatcctat acgacggact
    10921 ttacactaca agagctaacg ggacaatcca agcttccgga agataattat tttgtacttg
    10981 gagataatcg aagagtttca aaagatagtc gttcgtttgg cacgatcaat aaaactgata
    11041 ttctaggtaa agcaagattt gtctattatc cacttgatga aataaaatgg atccagtgag
    11101 aaacaataaa gcgtgcagtc tgttgagact gcacgcttta ttgtttaatc caaaatcagt
    11161 ttactacctt agtacgtaaa atcaaacagc tcgtttaaac acttttctag cctctaaagt
    11221 tttgataaat gaataaacaa ccattatttg aatagggatt tggatcatat tcctgatgaa
    11281 tctacctaga aaaattactt tgaaatctgc accaaacaaa acagacatca gccaagaatt
    11341 gataaaaagg ctgactggga tcataatcaa taattgggca gcgatgacgg aaggcaggtt
    11401 tatcttttta tgatataaaa ataagccatt aataaatcca ccaaggaaag ccgtgataag
    11461 aaaagcagct tgaaacgttc ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat
    11521 ttcaagcaaa ccagcccaga tcggtccata tagataaccc ataagcgcca tacttaaaaa
    11581 tccgaatgtg atttgaaaat aagcaggacc aatcgctatc ttgtataaga tgacatcaag
    11641 ggctaataaa agagcagagg tcgacaacaa tcttgcattc atttcgggca atctaaaaac
    11701 gtcttttgca atcaaagtgt tcaaaatatt ctctcctttg tcagttaata ataaaaggat
    11761 accataaaat caccaatgtg tcatgacaca ttggtgattt acatacactg gcatctaaca
    11821 attaaaaaaa gggtgagaag actgctttta taaactgtaa aaaagagatt gtacgaataa
    11881 aaaaaataga ggcggagaat acttatcgta tcatccgcct ttgttttttt gttataaaaa
    11941 acgtcagatt agttatctgc ttacatcttc atccatacgg gttctaatgt atttccgtct
    12001 agatcttgga cttctaatga aaacatttct tcttcaggca ttcccatatc tacttcgtgg
    12061 aaagtaccac cattttcttt tgcaatttga gcaaattttt ttacttcatc cgcgttttca
    12121 acactaaacg aaatcaaagc accacttgtt tttttattat cagctatttc tttatctttt
    12181 at
//
LOCUS       DARBDN010000079        12108 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000079 DARBDN010000000
VERSION     DARBDN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.080"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..695
                     /locus_tag="SCH06_002135"
     CDS             <1..695
                     /locus_tag="SCH06_002135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HEG1078681.1"
                     /translation="LVTVAKRPLDRIDQEAVFCQELAIQGTLLPLTETYLKEYFPELH
                     ATEAFTVLQAFFLSRVINHLIAPIQNKIMAETIEKMKQDSKEIYAKNNSFLVASLSEL
                     KITDTYLPDIATSLTLLVRRLKERYLQDRKKIIFLLEGDLYVCQSIRSRVLHYFGKRH
                     DLFFMTIQALSDEFLAQEDIDLVVTNYSDYLSEYTVNTDYLLLKTVPDSQDWRLLFQK
                     IEPQLSTLIGLN"
     gene            complement(753..1748)
                     /locus_tag="SCH06_002136"
                     /pseudo
     CDS             complement(753..1748)
                     /locus_tag="SCH06_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558311.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1849..3063
                     /locus_tag="SCH06_002137"
                     /pseudo
     CDS             1849..3063
                     /locus_tag="SCH06_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738897.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase
                     domain-containing protein"
     gene            complement(3157..3461)
                     /locus_tag="SCH06_002138"
                     /pseudo
     CDS             complement(3157..3461)
                     /locus_tag="SCH06_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738896.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3975..5488)
                     /locus_tag="SCH06_002139"
     CDS             complement(join(3975..5327,5330..5488))
                     /locus_tag="SCH06_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179228.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1078682.1"
                     /translation="MYTYEERKKAVDLYFKYDQALAATTKKLGYPSVGALRQWIREFQ
                     SSDKLHKNIRTSWKYTLAQKEVAVNHYLDYGQCYARTIRKFGYPNKTTLRKWLEEYAP
                     STRKVRQNSIHYTKQEKEAAVLALCTRSLSAKSIANDFGVTRQALYLWKNKLLGKGAT
                     KPLKSMNVTPEIKLLKEERDILQREVYKLRLEKEILEQASDLIKKEPGIDPIILTNKE
                     KTQVIDALCSKYSVIELLRILDLPKSSYYYHRKQLAIPDKYLKERSLIVQLFHDNKGR
                     YGYRRIYCSLKLLGITLSEKVVRRIMTEEKLKVKSLRLRKYNSYGGEITPAVPNLLKR
                     DFKADQPNKKWLTDITEFHIPSGKVYLSPMIDCFDGAIVSWTISTKPNADMVNSMLEN
                     AIATLNAKDSPIVHSDRGAHYRWPGWIKRMKEACLVRSMSKKGYSPDNSACEGFFGRL
                     KNEFFYGQDWKSTSIDQFITDLDNYILWYNKKRIKCSLGGLSPLDYRKKLGIL"
     gene            complement(5811..6653)
                     /locus_tag="SCH06_002140"
     CDS             complement(5811..6653)
                     /locus_tag="SCH06_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEG1078683.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGYGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTEIAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            6978..7394
                     /locus_tag="SCH06_002141"
     CDS             6978..7394
                     /locus_tag="SCH06_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEG1078684.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIRESQQSVIDCRKLLVEQLTGGDDL"
     gene            7391..7861
                     /locus_tag="SCH06_002142"
     CDS             7391..7861
                     /locus_tag="SCH06_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078685.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            7875..8648
                     /locus_tag="SCH06_002143"
     CDS             7875..8648
                     /locus_tag="SCH06_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078686.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            8662..9474
                     /locus_tag="SCH06_002144"
     CDS             8662..9474
                     /locus_tag="SCH06_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1078687.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            9528..10493
                     /locus_tag="SCH06_002145"
     CDS             9528..10493
                     /locus_tag="SCH06_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1078688.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            10630..>12108
                     /locus_tag="SCH06_002146"
     CDS             10630..>12108
                     /locus_tag="SCH06_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1078689.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQE"
BASE COUNT         3951 a         1957 c         2274 g         3926 t
ORIGIN      
        1 atttagtaac ggttgctaag cggccgttgg atcggattga tcaggaggca gtcttctgtc
       61 aggagttggc gatccaaggg actttacttc cattaacaga aacgtattta aaggaatatt
      121 ttccagagtt gcacgcaaca gaagcattta ctgtcttgca agcattcttt ctttcccgag
      181 taatcaatca cctaatcgcc cctattcaaa ataagattat ggcagaaacg attgagaaaa
      241 tgaaacaaga tagtaaagaa atttatgcga aaaataattc gtttctggtt gcttctttat
      301 cggaattaaa aataaccgac acttacttgc ctgatattgc tacgagttta acgttattag
      361 tcagaagatt gaaagaacgt tatctacaag atagaaagaa gattatcttt ctgcttgaag
      421 gggatttgta tgtctgtcaa agtattcgtt caagagttct tcactacttc ggcaaacgtc
      481 atgacctatt ctttatgacg attcaagctc taagtgatga gttcttagcg caagaagata
      541 ttgatttagt cgtaacgaat tacagcgatt atttgtctga gtacacagta aatacagatt
      601 atctactatt aaaaaccgta ccagatagcc aagattggcg attgctattc caaaaaattg
      661 aaccacaact gagtacgttg attggtctga attaacttga agcctattta acttttttcg
      721 ttaagtaggc tctttttttg cgtcttgaat tgtcaaatca agtgcaacac tttattaaag
      781 aagacttcat aaggtgtttt ccaacctaga cactttctag gtctgctatt tagtttttca
      841 accatccgat aaatcgttgc gtcatctacc gtgtccatct cttttgattt cggtaagtac
      901 tctcgaatga gtccattcgt attttcattt gttcctcgtt gccaaggggc atgcggatct
      961 ggaaaataaa agggcacatt attcaatgct tctgtaaccg cgaaatgatt ggagaattct
     1021 tttcctctat ctggagtgat cgttttgacc acatcattgg ggatactgct taaaagttca
     1081 atcatttttt cgctcacgta agcagctttc tttcttggta cctttccagc taaaaggaat
     1141 cgcgattttc gatctgtcaa cgtcactaaa caagcaccac cagtttttcc agctacagta
     1201 tcggcttccc aatgtccaaa ttcacttcta tcgtctgcag attttggacg atcatgaatc
     1261 gaatgcgtaa tgcgtatttt tccacgagcc tcgacatgat tttttgtatg tcttgttttt
     1321 cctcgatggc gtaatgaacg gatcagccct ctattgccac tcgagagcgg ttctgtatcg
     1381 aaaataccgt tgtaaatggc acggtagacc gtgataaaac tgattgagaa gtccacctgt
     1441 tcaagcttca aacgattaga gatttcctct ggcgaccatt gaaattctac aaataaatga
     1501 cgaacgattg accaaattcg cggatcattt agaatagaat gacgccctca gtcctttcta
     1561 cgagaagcat actttttgtc tgctttggaa ggtgagtagg ttttctcctt gtttcttctc
     1621 aattcacgtg aaatggtaga cggactacga tgaatgtcat tgccgatttt tctaatagaa
     1681 acaccttctt catgaagtag aaagattctt tctcgttcga gtatggtaag atgatggtac
     1741 tggctcataa ttgtcttcct cctagtagtg ttctcgacaa acctattcta gttggatatt
     1801 gattatgagt cattttttag gtgttgcact taaagtgtaa attcaaaaca caaaaaaaag
     1861 gtgttagtaa aatataaggt taacgacgca gggagcaggc ctgtcaaaat caagccgcgg
     1921 gaactttaca gagcttcaca tttagattct tgcatctaca gatactacgc agaatgtcta
     1981 aacaaagatt atgaaaaagt agcagaaata agaagaattg gtgataatgt tgttgcttat
     2041 agggttggaa aaggtaaatc aaacatagac tatgcggctg aagcaataga ttttatcaaa
     2101 agaagcaatg atggctgtta tattttttta ggagattttg aaaaattttt tgatactttg
     2161 gatcatgaat atttaaagtg caaattaaaa gaagtcttaa gtatgagcac attggatgaa
     2221 gattggttta aaatttttaa aacaataact agtttttctt gggttgaaca aaaagattta
     2281 aatgatttat tcggttcaga aaaagaacaa tataagaatg gtttaaaatc ttattttgat
     2341 acgtgggaag aatttaggaa ttttaaagca gatggtcatg tatgtaaaaa tactaacagt
     2401 tttggaattc ctcaaggaac cccaataagt gctttgctat caaatatata tatgatagat
     2461 tttgacgatt ggctaaataa attatcatcc aaatatggtg ggaaatattt aagatatgcg
     2521 gatgatttca ttttgatact gccctttagt acaacctcta aggacatttt tcttgaaatt
     2581 atccgagaga ttctgcaata cgcatccgag gtcactaagt taaaaattga gagaaataaa
     2641 acagagaagt atctttttac aaatgattca gtatatttgt ttgagtcaaa taaaaatagt
     2701 acatcaagtc tagtaaaatc aaaattggat tacttgggat ttgtatttga tggaagccaa
     2761 gtaaagatga gacaaaaaag tgtttcaaaa ttttatagaa aagctgataa agcgatcaga
     2821 gctgctagag aaaaaagtcg aattaagaaa tcgagttatc taattggtaa aaggcatatt
     2881 tatagatatt tttttgatgt gggtgtaagg gatagtaaag ggagtaaatt tggaaacttc
     2941 atttcctatg ctagaagatg tcaaatgaaa tttgatcaaa tatctcctct gacggagaat
     3001 ttaatgatgg aacaaataaa aaacagacgt aaaaagctat taaagaaaat gtataagaac
     3061 tgataatcaa atgatatgct cccatcatag tagacgttag aaaaaaatat tgataatcta
     3121 ctatgatgag aatttatcaa atcgtgactt tcatatctat cgtccattaa ccgctgaaac
     3181 aaacaccaaa taattcgcga aatcgccaat ccgttgtcgg tggtcattca catcacttct
     3241 tgtacgttgt tcttgttctt cttgtaagaa taagcgtgat gtccaagaat gactgtataa
     3301 cgaatagcag cacccatcaa ctcttcccaa atttcgataa aatccttatc attcatatca
     3361 gcatttttta atatttcttg atagatagtg gtcatttcag taaaagatag cgcttctggt
     3421 tgttgtaaat aattttcgta tgtttgattc aattgggaca ttaaatcact ccttgaaatg
     3481 tttttgtttt aactagttta ctacaagaaa taaaagttag tgcatcaaaa gaaaaacagg
     3541 aaagcatacc attttggtag ttttttctcg ttgagttggt ataaatttga tgagacaaat
     3601 aggctagtat cactttattc attgatacta gcctattttg tatccaaaat ttatgaaaat
     3661 gattaaaaca aatctttttc ttgctcaatg aattgagcaa atttatcagc acttcgttct
     3721 tatcgttctg gataaaaata gttgtagact tgttttgtca tttttgaatc tttatgtcca
     3781 acacgataca taatatccta tagtttcatg tctgccattg cgcacaagga aacgtgagtt
     3841 tttctaaatt catgaagagt tatccgtttt tcaaggtgat atttattagc gatcatgtca
     3901 taccaatcat ttggtgtcaa gggcatctta aaattgtagg tttgggggtg cggacgtttt
     3961 cctgcaccaa aattttataa aatacctagt ttcttacgat aatctaatgg acttaatccg
     4021 cccaatgaac acttgattcg ctttttgttg taccaaagaa tgtagttatc caaatcagtg
     4081 ataaattgat caatagatgt cgacttccaa tcctgcccat aaaagaattc attcttgagg
     4141 cgcccaaaaa agccttcaca agcagaatta tcaggagaat atcctttttt tgacattgaa
     4201 cggactaaac aggcttcttt cattcgtttg atccaacctg gccaacggta atgtgcgcca
     4261 cgatcagaat gaacaattgg agaatccttt gcatttaatg tggctatagc gttctctaac
     4321 attgaattga ccatatctgc attgggtttt gtgctaattg tccaactaac gatagctcca
     4381 tcaaaacaat caatcattgg agaaagatag accttcccag agggaatatg aaattctgta
     4441 atatcagtga gccatttctt gtttggttgg tcagctttaa aatcacgttt taaaaggttc
     4501 ggaacagcag gagtaatttc tcctccataa gaattgtact ttcttaatcg aagtgatttc
     4561 acctttaatt tctcttcagt cataatgcga cgtaccactt tttcagataa agtaattcct
     4621 aataacttaa gcgaacaata aatacgacga tagccatatc ttcctttatt gtcatgaaat
     4681 aattgcacaa ttaaggagcg ttcttttaaa tatttgtctg ggatagctaa ttgtttcctg
     4741 tgatagtaat agctactttt gggcaaatca agaattctta atagctcaat tacgctatat
     4801 ttggagcata aggcatcaat cacttgtgtt ttctctttgt ttgtcaatat gattggatcg
     4861 atgccaggct ctttttttat taaatcagac gcctgttcta aaatttcttt ttctaagcgc
     4921 agtttgtata cttcacgttg aaggatatct cgttcctctt tcaacaattt gatttcagga
     4981 gtgacattca ttgatttcaa aggtttagta gctccttttc caagcagctt gtttttccat
     5041 aagtacaatg cttgtctggt tacgccaaaa tcatttgcga ttgatttagc agagagtgaa
     5101 cgagtgcaca gggctaggac agcagcttct ttttcttgtt ttgtatagtg tatcgaattt
     5161 tgacgaactt tacgagtaga tggagcgtat tcttccaacc attttcttaa agtagtttta
     5221 tttggatagc caaactttcg aattgtacgt gcataacatt gcccataatc taaataatga
     5281 ttcacagcaa cttctttttg agcaagcgta tatttccaag aagtacgttg atatttttgt
     5341 gcagcttatc tgaagattga aattctctaa tccattgtct gagggcacca acagaaggat
     5401 atccaagttt tttagttgta gcagccaatg cttgatcata tttaaaatat aaatcaacag
     5461 cttttttccg ttcttcatat gtgtacatga gacgtcctcc aaacttattt cagtccaagt
     5521 ttttgtccgc atgcccttgt atgtactttt attctgccat aaacagctta atgaatgtcc
     5581 acttgaaaaa gtgaataaac gaaatagatg actcgattta ataaggaagt aaacccacac
     5641 agaaatatag gtgattttcc ttgaatgacc aagatattga aagttagtga aaaaacacaa
     5701 aaaggtagcc ctattcacag aaggtctgcc ttttgtgtta tcgccagcaa acattagagg
     5761 ggatatttca tatagctttt gtcctctcga cagtcctatc agtttctctt ttaacttatc
     5821 tctaagtgct gtccagtttt aatagcttct agcttgtttc ctaactgtgt ttttaatatg
     5881 ttgaaggctt ttgaacctgt gcagtggcaa gtaaggattt tttctactcg tgagtcattc
     5941 aatttatttc caattttcat tacctcttgc tcaggtagac ctaaattatt tatataaggt
     6001 atgccaatca tatggaagcc accgattagg tattttatgg gtttagtcgg aaatgtttca
     6061 agagcaattt ccatcatatc gataatgcca tgatgactac agccagtaaa gacaatcaga
     6121 ccgtcttctt gctcaattac gaccaataat tcatctgaaa aatcatcata aacaaattta
     6181 tcatccatct ttttgtataa attcttggtg gtcgagtttg ctttgcctag ggggatgata
     6241 tgaaagctcg gagcaatttc tgttttcgtt tttattgtat gtaaattctc atgcatttta
     6301 aggatttcat ttttaggaat accaacatac agaaacgtgg ttaaaatctt taaataatgg
     6361 ggtaaagtta caccttcagc tgtataaata ggggcgtttc ctgattttaa atatcttaac
     6421 ccgccggtgt ggtcagaatg accgtgtgaa ataatcactg cctccagatc attcaaagtt
     6481 tcccccattt tagtcgcatt atagactaat tttttattag cgccagcatc gaagagatat
     6541 ttcttccctg agtagttaat taagagagat aacccatatc cacttttaaa gttcaaattt
     6601 attcttgagt tttcaaataa aaccttgatt tccactataa catctccttt cacatgaacg
     6661 tgtattcata tattgtagca cattaagttc tattttttgt tgtaattacc gaaaaaaata
     6721 ttaatggacg ctttttacgc tttatttcgt atgtggaaga aaatttctta ggatgtggcg
     6781 ggggattggg gcaaagctaa attccaatta cagtgatcat ttaattagac acctttaaat
     6841 acccacactt tcatcaacac tataatttag ggaaagaaaa gtgttggcat gatatagaaa
     6901 aacctttaat taacagcgtt tcctaaaatt ggcacgcatc ttgcttatag aaaagcgtaa
     6961 ggataggagg aatgaaaatg gcaactataa ttcttgccag ccatggggaa tttgctcaag
     7021 gattaaagca aacagcgaca atgattattg gagatagtgt accaattcat gccttgtcag
     7081 catttagaga tgaagatgaa tctattttgg tacaaataaa aaaactttta gccacaatag
     7141 atatagaaga aacctacatt ttaactgata ttctaggtgg tagtgtgaat aatgatatgc
     7201 tcactattat taaagagtat gagggattgc aattaattac tggaatgaac ttacctttag
     7261 ttatttctat tgcaacctat aatggaaaaa ttggggaaag tgagctagaa aagcttatta
     7321 gagagagtca acaatcagtg attgattgta gaaaattatt agtagaacaa cttactggag
     7381 gagatgacct atgattaaat tagtacgtat tgaccatcgt ttgttgcacg gacaggtagt
     7441 attttcttgg agtaaatcat taaatatcaa tcgtattatt attgccaata aagaggcagc
     7501 gaatgatgaa ttcaaaaaaa tgtctttgaa tttatctaaa ccgactggca ttaaattaac
     7561 aattttttca gttgaacagt tactagaaaa aatgcctaaa atcgaaacac ttaacgaaaa
     7621 tatcatgctt atttttggta atacaaaaga aattcgtcaa ttttgtgaag cctatcctaa
     7681 agtacaagaa atcaactatg gagggataat caaaaaagaa ggttccaagc aatttagtaa
     7741 tgccattttc ttgaatgaat ctgagcaaga agatgccaaa aaattaaaag ctcttggcat
     7801 taaacaattt attcaacagg taccaacttc taaaaaagaa gatttgaata caatgttata
     7861 aaggaggaat gaaaatgctc gttcagtcaa ttggtttagg gttaatcggt gttttttgta
     7921 ttttagactc aaggctttta ggaagaatga attttgaacg accgttgatt gtcagtacgc
     7981 ttgttggttt ggtacttgga gacatggaaa aaggattaat tgttggagcc tctttggaat
     8041 tgatgtcctt aggattagta aatatcggag ctgctgcacc acctgatatg aatatggcat
     8101 caattattgc tacagccttt gccattttat caaatgcgaa tgcagaagca gcattaacga
     8161 ttgccattcc aatttcagtg ttaggtcaaa tactaggtat cttaatgcgg acgattttgt
     8221 caaatttgac tcacgttgcg gatcgcttta tcgaacaagg aaaatttagc caagcaagga
     8281 gaattcatat actttatggc tcgggattat atgctctcat gtattttatt cctatttttc
     8341 tagcaattta ttttggaacg aatcttgttt ctcagattgt tgatgcgatt cctgagtggc
     8401 taacaaatgg cttaacggtt gcaagtaaaa ttttaccagc atatgggttt gcgttgttat
     8461 tacaaacgat gttaacgaaa aaaatggtgc catttttatt acttggattt ttaattactg
     8521 cttattctgg attgggaatc attggtattg cagccttcgc atgtattgtt gcgtttgtca
     8581 tggttcaagt tcaaggtaaa aactcaaatg gtaaccaaaa tgagccagat ccattagatg
     8641 acttataagg aggtagatta agtgaaagag aaagatcaaa atgcatggaa atatcggcag
     8701 ttcttatggc gttcatgggc aattcaagcc tcatggaact atgaacgaca aatgaacatg
     8761 ggttttatgt acggaattgc accaattcta gataacattt acaagaatcc agaagatgaa
     8821 gcaatgaaga aagaagctta cgagcggcat atgatgtact acaactgtac ccctcaaaca
     8881 agtgcatttg tgttagggtt aactgcttct atggaggagc aatactacga agaccaagaa
     8941 aactttaatc cggaatcaat cagtgcagtg aagacttctc tgatgggacc gctatctggt
     9001 gttggtgatt ctttctttca aggaacgatt cgggtattag cctttggact aggaattaat
     9061 ttagcccaac aaggtagtat tttaggtcca attctagcaa tgttaatttc ctttgtacct
     9121 tcctttttag ttacttacta tggtgggaaa attggctata acatggggaa taaatacttg
     9181 tctaaactgt atcaagaagg tttgatggat aaagtaatgt atgtttgctc cattgtgggg
     9241 ttgatggtca ttggttcgat gattgccagc atgatcggga ttacaacacc aattcaaatg
     9301 ggtaaagctt ttgtcttaca agatgtatta gatagtatta tgccacaatt tttaccatta
     9361 ggattaacct tcttcatgta ctggttattg cagaaaaagg tcaaaacagg atggatgttg
     9421 gcaatctgtt tagtcggagg aattattttt agtttgttag gtatcttaca ataagggaat
     9481 aaccaataaa tttggttgaa taatataaat aaggaggaat tcaattgatg aattcaaaag
     9541 aaattgttaa agaaatcgta gcgaaaaaag aggtaaaatc aatcgtattt gttggctgtg
     9601 gcgcttcaaa agcggacctt tatcctgcaa agtattttct agaccaaaat gcgaagcagt
     9661 tacggattag tcattacaca gccagcgaat ttaactatgc aacaccagca tctgtagatg
     9721 agtcaactgt cgttatttca gcttctttag gaggtacgac tccagaaaca gttgaagcta
     9781 acgcagtagc taaagaaaaa ggtgctacag ttattagtct aacacgaagc attgactcac
     9841 cgttaacaaa agatgcagat tatgtaattt atcatcgatt tgcagagaac tatgctgcta
     9901 aattagaaaa aacaggctac tgtttagaat tggcagtaga acttttacat caagtagaag
     9961 gttatgacca ttatgaagca atgcaagaag gatttgctac tatctatgat cttgcccaaa
    10021 aaagtgcaga atcagctcgt aaagatgcga agaaatttgc tgaacgcttt aaagatgaaa
    10081 aagttattta tgtaatgagt agtggtgcta cacatgaagt agcatactca acatcaattt
    10141 gcttgatgat ggaaatgcaa tggattaatt ctggtacctt ccattcagga gaatttttcc
    10201 acggaccatt cgaaattgtg gataaagacg taccgtttat attattaatg aatgatggaa
    10261 aaactagaaa tatagatgct cgagcattaa ctttccttga acgctttgat acgaaaacag
    10321 aagttgtaga tgccttggat tatggcttgt cttcacatat tgctaaagaa gtcttagact
    10381 actttaaccc attcgtgatt actgcagtat ttagagttta tgcagaagaa ttgtcagaag
    10441 caagagaaca tccattaact aagagacgtt atatgtggaa actaacttat taaaaaatag
    10501 atcaaactaa ataaggtggc ttgagaaatt aagccacctt gttttcttca atgtgatttt
    10561 atacatatgg taaaataact agtacatatg gtaaaataac tagtacatat tgtgaaagca
    10621 ggtggcaaga tgcagcgatt aaatgactat ctttatcaac taacattgct tttgaaatct
    10681 acgccttcag ataattattc agctcgcagt atttcgcaag ctttacagtt gaatagaagt
    10741 acaatcagta gctacttaaa tgaaggtgtt cgtgaagggc ttttcataaa agtaaaaagt
    10801 tacccggttt tatttttaca tagaacagct cttgaagaac tacatatcac actgaataac
    10861 tccgaaatag aatcaattga aagcttgtta acaatttctc aaaaacccgc attagatcaa
    10921 gtaattggct ctaaaggaag tttgaaagaa gcaattgatc aaattaaaac ggcagtctta
    10981 tatcctggaa aagggttgcc tttattattg atcggcgcta gtggatcagg gaaaaccttt
    11041 ctagcgaata aaatatatga atatgcagta gaagaaaagg tcattcacac atcggcacct
    11101 ttcatagatt ataattgtgc acaatatgtg agcaatccag agttactatc ctctgcttta
    11161 tttggctaca cgaaaggagc atttaccgga gcaagccagg agcatactgg tttgctagaa
    11221 aaagccgatg gaggagtatt gtttttagat gaagtgcatc gcttatctga agaagggcaa
    11281 gagaaattat ttacatttat ggatacgggc gaattctctc ctatggggga taatagtatt
    11341 cggaaaaaag ccgatgttcg attagtcttt gcaacaacag aaaatatata tacgactttc
    11401 ttaccaactt ttcttaggag attgccagtt attgttaatc tacctagatt tcaacaacgt
    11461 ccgtcgtttg aacgtctgtc attgattgat gaattttttg tttctgagag taaaatttta
    11521 gctaaggaac tatctgtttc tgatgcattg attcatttct taatgaatag tgattttgaa
    11581 ggtaacgtgg ggaatattaa aaatattatc aagtatgctt gcggaaacgc atatatccac
    11641 cagaagagtc agcaaacaat tcaagttaaa ttattggata tgcctttaga gtacagttat
    11701 aaattcaagg agcaactaaa taaacccaga aagaaaagag cagatcgaat ctactatcca
    11761 gaagaaacac gacaagtgca actagaaaga aacaatcagc tttttgttca attttttgac
    11821 caattactta ctggattctc tgaagtgatt gaaaataaca aggatattaa actattttta
    11881 gaagaaatgg ttaccaaggt aacacaagta atggatacgc ttatttttca agaggattac
    11941 gaaaaagagc agtctttata cgccattcta aactatcata ttcgtcaaag tattgatttt
    12001 atgcgagaaa gctacgggtt tgaacaagat ggtaaccggg tagtcgcttt ggccaactat
    12061 ctatatgtca aggataatca agtgattttt gaaaatagtc ttcaagaa
//
LOCUS       DARBDN010000080        11669 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000080 DARBDN010000000
VERSION     DARBDN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.081"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(37..216)
                     /locus_tag="SCH06_002147"
     CDS             complement(37..216)
                     /locus_tag="SCH06_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078690.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(597..1304)
                     /locus_tag="SCH06_002148"
     CDS             complement(597..1304)
                     /locus_tag="SCH06_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078691.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(1297..1734)
                     /locus_tag="SCH06_002149"
     CDS             complement(1297..1734)
                     /locus_tag="SCH06_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078692.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(1749..2000)
                     /locus_tag="SCH06_002150"
     CDS             complement(1749..2000)
                     /locus_tag="SCH06_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078693.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(2000..2206)
                     /locus_tag="SCH06_002151"
     CDS             complement(2000..2206)
                     /locus_tag="SCH06_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEG1078694.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(2643..2903)
                     /locus_tag="SCH06_002152"
     CDS             complement(2643..2903)
                     /locus_tag="SCH06_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078695.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            2978..3181
                     /locus_tag="SCH06_002153"
     CDS             2978..3181
                     /locus_tag="SCH06_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEG1078696.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(3322..3807)
                     /gene="ssb"
                     /locus_tag="SCH06_002154"
     CDS             complement(3322..3807)
                     /gene="ssb"
                     /locus_tag="SCH06_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEG1078697.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(3810..4709)
                     /locus_tag="SCH06_002155"
     CDS             complement(3810..4709)
                     /locus_tag="SCH06_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEG1078698.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(4722..5315)
                     /locus_tag="SCH06_002156"
     CDS             complement(4722..5315)
                     /locus_tag="SCH06_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEG1078699.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(5391..5540)
                     /locus_tag="SCH06_002157"
     CDS             complement(5391..5540)
                     /locus_tag="SCH06_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078700.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            complement(5556..7760)
                     /locus_tag="SCH06_002158"
     CDS             complement(5556..7760)
                     /locus_tag="SCH06_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEG1078701.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(7771..9231)
                     /locus_tag="SCH06_002159"
     CDS             complement(7771..9231)
                     /locus_tag="SCH06_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEG1078702.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            complement(9292..11664)
                     /locus_tag="SCH06_002160"
     CDS             complement(9292..11664)
                     /locus_tag="SCH06_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078703.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         2892 a         2433 c         1958 g         4386 t
ORIGIN      
        1 tgctatcact tttagttttt aggataaaaa gtgacgtcac tttttgagtg ctggtacctc
       61 aaatcctgct ttttcttggg caatcaataa atctaacgca atacacataa tcctggattc
      121 acttttgccg tacttctgct ttagttgctg caattctttt tgtctctttt catccaacgt
      181 cacgggtaac cgtttatttc ctattgcaat tggcattagt actctctcct ttcatcgaaa
      241 taaccctatt aaaaatatgg ctgcaatcaa cttgaatatt agactcacaa gggttaacac
      301 aaagcgccaa aagatcaaac aaaataccag tattcctaag aatactacga agtttaaatg
      361 tagagctgca ccatgacgca taagtatctc gccaacaaac agtacgaaca atagaggaat
      421 gattttattc atatggatct ccttctttct cttaggttat cgggctttgc ccgcttattt
      481 cgcaccacct aagcggcggg ggcggttgga tcgattggtg cgaaataaga accattccct
      541 taatttcaag gttttttgtt cttatttcac acatcctcac ttttcggtat aaatggttat
      601 tgaccttttt tcctttcaaa tcgttgatat ggcattcgtt tacggtcaag ttcattttgg
      661 atttcttctg tatcgtcgta agtgtaggtg tctaaaaaat cagttaaagt cgtgtaccag
      721 tcgtcgcctg ggttatctac ttcttctaca tattccctca aaaatgcttc gggtacagtg
      781 agttcataat ccattcccat taacacgata gattccgtcc cacacgtcaa aaatctagta
      841 aatacaaggt aataatcgtc taccgtcgca tctttgctgt ttagctcttc catttcttct
      901 tccattaatt ccatgctctc aaaaattgaa taatattctg attctgagta atagtgtttc
      961 ctgcaaatcg tgtagctgac aaagttttcg accagctcac tcctttctag gtaaacattc
     1021 atgatatatt tttctgtttc tagtcgtaga agctccgctc ctttttttaa tgtgtcagga
     1081 cgacgtttat acacgtctaa acgattatgg ctgactgtaa ccttcgtttg actcgtttca
     1141 ctttccatat acaactgttc ttccactctt tgaataaagt acttcatttc ttccatacaa
     1201 ctaaagtctt tttgaatccg tctgattact tcattcaagt gttctttgtt tgttaaaaat
     1261 tgcgaaacat cttctgttgt tagctgataa accaccttat tcattatctt tctcctccga
     1321 ttcaatcgta taaaatgcac catttttttc gatattttca aaagtatcta gccagtcgct
     1381 agccattgct ttagctttct taatctgtgc gaattttgca taagtcagtt ctaaggcttg
     1441 atattcggaa ggtttgatag tgcttggttt gacacctact tccaagcata gtaaggcttg
     1501 gaaaaaccat tttccatttt gttttttcag ttcttccagt gttcgatagt acgtcgcaat
     1561 gagattcatt tcgacacctg attcaatcat ttcttccact gcgactgaca atttttcctt
     1621 gtaatgtttt ttgggtacac gtgtttcatg gtataggaac gtcatatcct ccattttttg
     1681 tgccatttta tccaaaggta atttgacaaa ttcgtcatag taattttgag ccatattttt
     1741 tctccttttt agttctctaa tttggttaac caatattcga tttcataagt ttccatgttt
     1801 tcttgataat gcagttcata tcctgcaatc ttcactaggt cttcaaatag catagtcggt
     1861 gcatcctcta ctaaaggggt ttctatcgtc cagtaccgcg gaataagtaa agcttctgct
     1921 actttttcag aaatgacttc tttgtccacc aaaatttgaa cgacttcttt tacagtcaat
     1981 aatttgtgtt gtgttttcat caccgtttct ttactttctc atcaatcaaa acataatcgc
     2041 cataagacaa ggtatatttt ttcccgcatg ttggacattg atacaaacga tagcttttga
     2101 tacatttcgc tctttctcca caatcgcatt cgacagtatg tggtgcatga tagtttggga
     2161 ataattcgct gaagggaaca ccccaataat caaatttctt tcgcatgatt gattctgcct
     2221 cctcttagga aaggttttat ttcctttcgt tagttctttc tttattgatt tgttggccag
     2281 aatgaatcaa cgaaaagcga caaggacaag ggcgcgcagc gtgccattta cccttgtcct
     2341 tgtcgctttt tggtgataaa aggcaacttg ttgccggtct ggcaaatcaa taaagagata
     2401 gcgaacagga acgaaccttt tggtgagagg aagttttttc tattttgtct tgctttgcaa
     2461 gacaccatat cttagtgaac gtgcaacgtt cacttccttt cttctcgaac ggcggtggcg
     2521 gttggagtga gagaaaggtt tttcaattga gaaggcactt gtgtcttcct aaaaaggtct
     2581 tttcctgttt ctatgtaaaa caaaaagagc tgcaatcctc atttaggact gcagctcttc
     2641 ttttatatgc ccatcgatcg cgtaaaatga tcggggtttc taatttgcat cgattcaatg
     2701 actaattgat tccgtttatt gaaatgacct gtgacggcaa tattgtattt tccatcatcc
     2761 ataattaaca atttatcgat aatttcaata tctgcaacta cacaattaat cgattcatga
     2821 attgtttgta aagtaaagcg aaccaataat ggttgtgttt ttattactcg gattttatca
     2881 agcaaaccaa catatttgtt catcacgatc acctcgctaa aattatagca aaaacagcta
     2941 aaattgagaa tttttattcg attttagata tgctataatg atcaagacag taaagtttgt
     3001 gacggtggct atccgattga aagtgaggtg gtgcgtatgt gcgtacttcc aaaatcttac
     3061 agaaaggaga agccttttgc ctgttgaaac ggcgctagga ttaatgatta gtttcggttc
     3121 tttgatcgca acaatcattt ttggaatctt agcagttgta aacaacaatc aaaaaaaata
     3181 accgtcagct ttagccggtc gacgattatt tttcaaaaat aatattaagc tggtcaccgt
     3241 cttaaacggt gctgttaggg gagttgttag cgcaactcct cttttcgtat ccattataac
     3301 aactttattg atcttttaca atcagaatgg taaatcatca tcactaatat cgattgattg
     3361 tccgccaaat ggattttgtg aagcgttcaa tccattgttg ttaggcgtag ctacatcccg
     3421 ttgttcaaag gtggtagggc ttggactgct ggacgattga tcagcgtgcg cacggctttc
     3481 tgtcgctgct ttactttcta atagttggaa attatcggcc acaacttctg tcacatacac
     3541 acgttgtcct tgttggttat cgtaggttcg ggtttgaatc cgtccaacaa cgccgatcaa
     3601 actgcccttt ttagctaatg tcgccatcgt ttctgctggt ttgcgccaaa tcacacagtt
     3661 aataaaatca gcttctcgat tgccgttttg attcgtgaaa tttcggttga cagctagggt
     3721 aaaagtcgct actgcagtac cactcgcggt ataacgtaaa tctggatctt tggttaagcg
     3781 tcctactaaa gttacattat tgatcatctt tatctctcca tttcttgatt catttgttgt
     3841 gatcttttaa actgccgttt tctttcttga ttttcaattt tgatcacact tttcattagg
     3901 tgatcaattt cgttgactgt atctgtaaat gaaatggaat tcgcaaacgt gttaactgag
     3961 cgatattttt cccactgctt ttccaaatag tcatttcctc tgatcttatc catttctctt
     4021 tcataataaa aggacaacgg ttttgtatcc ccacgttttg taaatgtatt tcgaacactt
     4081 ttgtataact ctttcgtatc gatattttct agtttcggaa tggtaaataa gtcgtagtaa
     4141 tcttttgctc tcgaattatc tgtgccaaag ctgaacgtag cacttagctt ttctgcaata
     4201 atttgttctg ttggataagc tggaatctcc acttttttat cttcaaacat taattggtga
     4261 tagtgtgtat ctacttcagg ataaatagaa tctcctgttg tcacgtccat tttaaacggt
     4321 acacgtactt tctctaaatt agccaccaat ttaatttgaa atccaggata aaaatcggct
     4381 tctcttgttt ccttcattcc ttgaatagag aaaacaatgc cttcttttgt gggttttcta
     4441 gttaaatcat taaaaatgct cttcaatttt tcttcagtta atttgctatt tctaaatgtc
     4501 gtatcgatat caattgttgt ccttctatcg attccatatt ttgatcctaa taaaaagccg
     4561 cctttcaaaa tgaagtcatt tttgtacttt gattcagaaa tttgttcaat tagacgatcc
     4621 atcataaaat gccgttgcac taactgtgca tttaatcctg tactctttgc taaatttctt
     4681 gtttttgctg caaattgtgt cggtgtcatc tttttcctcc atcaatataa gctttgcatg
     4741 tggtatttca tttctttttc tacatgtagt tttgtcatgt aatctcttaa tttacttgga
     4801 tctctcaatg ggtcttccat gtactctttt aatgcttcta atttcatttc atattcaaat
     4861 tcatatctcg gattccaaat atcacaaagt gtacgctctt tatcatacat agtaatagga
     4921 tttccttgaa aggaagttcc ctctactttt cctagttcat aaacttcttt cttcacgaaa
     4981 tgaaattgta actgctgctc ttttgtaatt gaacgatcaa cgttatagcc atggggaaaa
     5041 gttaagtgaa tgaatttcgg catattcgta gaaagctggt aaatatctaa agtcgtttca
     5101 tgagagaaga ttcccctgga aaatcgttgc tgaagccaaa ataaatcatc tattccatga
     5161 ccatcctcta cataataacc acgatcaact ttgatcaatt ttccttgatt caccaatctt
     5221 tgtacagtgg ttgctgcgat tccaaatttc ctggcttcct tcatagataa atttccatcg
     5281 cgaatagcca acaattcttt cagtttatct tgcatttact tcccctccct tcgttacaaa
     5341 tacactacat caaatatatc atagtagttt atttgtaaca agattaacgt ctatcgatct
     5401 aattcgattt ctttttgaat gcgctgctgg ttctttaatt gttgcagtct tcttttattt
     5461 gcacgtaatt tctcttgttc taaacgaatt tttgcttttt gattttcgat ttcttgttgt
     5521 ttgtgtgttg tatttcgcat aggataaccc cttcattatt ttgtagtgcg gcgtgttctt
     5581 ttcttatagt tcgttttttt cttttcagaa aattcaaagc ctgttgtaaa gtcttctttt
     5641 aaaacgatcg ttgcttcaaa cgaacctttc tgacctttta gtcctctgac tgattggctt
     5701 gttcggccgt tttgaatgat ctctttcagt tgtgtggctg tgagtttctt tttggcaatc
     5761 gttgtccata atttaaaatc acaggcttca gacgtacatg ccgccacatt ttgataaagc
     5821 aagacttctt gttcccgaca ttttggacaa acacctaaat gacgcgttgc ttcctgtttt
     5881 tcactggctg ctttcacctc ttgtaacgtt gatccaaaat ctgttgactg gatttgtccc
     5941 ggtacgactt ccaacaagtg agagacaaat ttttggatat tagctaagaa agtagcttgt
     6001 gttcctttct gctcaccaat ctttaataag taactttccc atttggcggt catttcggca
     6061 cttgttagca gcggctcttt ttccacggct tggcaaagta aaatcccttt atttgtcacc
     6121 acaagcttat ttttttctac cttgatatat tccttttgtt tcaaagtttc aataatattt
     6181 gctcgtgttg cttctgtacc gattccttct acttctttca atatggattg tgcttcttcg
     6241 ctatccacgg tttttccagc tgttttcatc gctgtgatca acgtaccttc ggtataaggt
     6301 tgtggtggct tcgtttcttt ttcaaggact tgtagatcta ccgtcaccgc ttctcctttt
     6361 gtcactttag gaagtagcgg ttcttcttcc ttttcttttc tgtcgctctc tttgccaaac
     6421 agctttttcc aacctagatc tactggtact tttccgactg tctttagctg aagctgctga
     6481 acttgcgtca agatcgttgt ttcttcatag gtatactttt ccgcaaacat ggccaccgtt
     6541 gtttttaaca cttgttcata aatagcctgc tgcagtggac ttaattgttc aaaagccgct
     6601 gccgtcatga ccgtctttgt aggaatgatc gcgtaatgtt cctggacttt cttattattc
     6661 acatatcgac tattcggtgt atgaatagga gtaggaatgg cttcggcctt taaaaagtgt
     6721 ttgtattcgt ctaagtgatc caacagatac gcatactccc cttctgtaat ataaggggta
     6781 tctgttcgtg ggtagcttag atatttccct tcatacaacc cttgcatggc ttccaaagta
     6841 tctttggcac tagctttcat gagctgattc attttagatt gaaggctgga tagagaaaaa
     6901 agacgtggac ttgccgcact ttttttctcg gtttcaactt ggtggatcgt acctggctgt
     6961 tttcccaatt gaaccccctt ttcttttaaa taatcttcaa atgcttcttg cgtcgcttgg
     7021 gtttcattcg gatcaagctt cgcatcaaat gcgccatttt gagcgattac ttgggctttt
     7081 ccttcaaaat atggttcttt ttggaagttt ctaatctttt cctgtaattg ataaatcatg
     7141 taaagcgttg gggtttggac tctgcctaag gaaaaacttc ctggtatgcc tttttgctgc
     7201 aagagtaaac tatacagcgg gctaccgttc atgccgatca accaatcggc gatctggcgt
     7261 gcttgtgctt cttcaaattt tgggtaggtc tcttctgcat ctcgtaactg ctggaatccc
     7321 tgataaatgg cttctttttc taaggagttg atccaaagtc ttttaaatat ctttccatga
     7381 tcggcgcctg cttgttgaat gatcgtccaa gctatcagtt ccccttcacg atcgctatct
     7441 gtcgcaataa taatggtgtc ggccgattga agttgctgtt tcaccacctt gaattgcttt
     7501 ttcttatctt taggaacatg atagtgataa tgtgtaggga aaataggcaa atgctctaat
     7561 gaccattgtt tccaattttc atcgtacata tcgggcgaat ctaactcgac taaatgacca
     7621 aaaccatacg tgatcacagt ttctcctgaa aacaatcgat cttggatctc aaaataccca
     7681 tcttttcggg tagctttaga aaagctatcg gcataagcct tcgcttgtga cggtttttct
     7741 gctaaaataa cggttttcat catgacgatt tcactccctt tcttgctgtc taccttgttg
     7801 aaacaacatg gcacgttttt gctttctgat ctcttgttgg tagatttcat gcttcaattg
     7861 atcattccaa tcctttttta cttcaggtac aaattcatgt tcatgatttt tatagccttt
     7921 gtagtattgt tctgctttat aagagaaaag aatctgagca ttaatatccc ctttttcttg
     7981 ataaaaacga tcaaaatcgt acgtaccatc cacgcgttca caagctttta attcttttgc
     8041 gacttctcta caaatatctt tcaaattaat agcttctatt gaatcgttaa cagaaagctg
     8101 ctgaccaaaa gacgcattta ctttgtgagc ggaaaccaat tggttcgtta attgcagatt
     8161 gttttctgtc ttgtgtatgg ccataatagc ttctggtgtg atcttttctt cttttgcgac
     8221 ttcttcataa atgactttgt attcttttgg cacttgccaa tcattagcga ttcctcgttc
     8281 acaacgtact ttctgattcg taaatggatc aactgcgccc attaattgtt ctttttcgta
     8341 gaaaatatgt cctgcacggt cattatccac acaaatctcg atggattgag gaaaggcttg
     8401 tttctttctc aattcagata ctgcctcacc aaaataatga ctgatcacat ggtgttttaa
     8461 cccttccatc gaaactaacc acgtatcgtt taactgatca cgatttagtg cagcatagct
     8521 aagtaaatca atactactct caaaaaattt taactgctta gggtcaccga tctttaggtt
     8581 aaagccatga ttcgctgtcg aatttttatc tatatgctta tatgtgcctc tctcaccaaa
     8641 acgttcataa tcaatgaacg ttccttgata actcgcccct actgtctcat ttgtctgtgg
     8701 atctttccat aaaaaggcga ccgcatgatc taaacgatcg tctcgaacta agaaattttg
     8761 ccgttcatgt tttggcttta gttcggcaat caacccttct ttttctgcat aatcaatcag
     8821 ccactctggt agttttcgtt cttccttcag ataattcctt cctttttctg tgagtggttg
     8881 ataatcaacg gggtgatctt tgtacttttc tgtctcaaaa tgaagatttt ccactcgttc
     8941 tgttttgtct tcattcttta gaataaaatc agtggctgct ttaaattgtt gcttagggtc
     9001 ttggatctct ttgtctatga aaaaaagttt agctaattca ataatgtcgc cactaatatt
     9061 ttgactgttc caataaaaac gttgttttct tcgatcaaaa acaaatgaat catggtcttc
     9121 taagcgatag tctcgtcctt tattgactac agccattcca ttgtttcgag caaaatccac
     9181 tatatcgatc tgtttacatc gatcaataag actcattttt ttctcggtca ttttaaaacc
     9241 tcccaaaaga aaaaagacta tccgtttttc agatagtctt ttttacttgt tttatacacg
     9301 ttctttttgt gacaattgtt gttcataata gatttcattt tttcgttttg ccacttctga
     9361 cactgtctca agtgaaaatc ggaatgaatt tcctagcgca aattcttctg aaggtaacgc
     9421 cgtttggatc tcttttccat aactttttcc ttttaaaatt acttgattat gctgtggatc
     9481 ttcaataaac gccgcatcct tcaaatgtaa cgttcgaccc gtatcttctt ccattacttt
     9541 cccgtctttc ttgtcgatcc aaagtgaacc aacaggaaca atattctttt gttctgccgt
     9601 ttctacagta tttttatgct cctgcttcac ttctgctggt tggatctctg gttctctttc
     9661 tctgtattga ttgatttcat tagaaatggt ttgaatgaat tcatttgcga cacggctgac
     9721 atcattcatg attttcccac gttccgcagc ttccttatca tccaacgtct gaccattctt
     9781 cgtccatgct gcaatataag gaatagcttt ctccgaagtg tccattccaa aatgtttgca
     9841 cacaatataa gaagtcattt ctgcctgcaa ttctttagtt gcggtatcta attctgaaaa
     9901 tttgtgcatt cttgcatggg ctaattcatg aatacttgta gctaaatgct gcgtaggagt
     9961 atttcgagta ttcatgacga tttcttcttc gccagtaaat tcgttacgaa catatgcccc
    10021 ccgtgcttgt cctaattctc tttgatagac ttcactttct gtcatatctc gaatttgtat
    10081 tccaatattg ttggctaccg cttgaatccc agcttgaagt tctgactgtc cttttttatc
    10141 caattgaaaa tcaaagacac ggttcggaaa gattttcgga tagtcttcag gttttaactg
    10201 tgtttgtgtg atatcaaaca ctttttcaat cgtgtagtaa ggttttttga tcacttcgat
    10261 ttgaccactt tcgattcgtt ttttatcttc tggtgtagct tctgtttctc gaacaaagcc
    10321 acgtcctttc tcataaaatc ctttgaccgt ttttctgaca aagatcttgt tcccttgttc
    10381 cccttttttg atatagattc cttctttttt caacgcagca cgacctaaac aagccgttgc
    10441 acctggaaat tgttcctcaa tcaataattg atttctaaag gatcgttctg gaaaacgaga
    10501 cataaaattc aaaagttctt tcacgtcttc aggagaatgg gtatgctttt tcaccgcatc
    10561 cagtgcctgt tgcgaaaggg atttgacttc ttgcttaatc tcttctgccg ttcgtttttg
    10621 atagcccttt tgttttgttt ttgtttcttt cgactgcatt tgttctttcg aaacaggttc
    10681 atttttgacc gtttgttttt gttccttttc aggtacttgt tcgcacaatt ttgctaactc
    10741 taaatagatg ggttgattac tgttgacgcc atcccctaga tccattcgga tctgatcgac
    10801 tacttctccg ttcttcactt cttcaaaata gaatttataa taacctgctt ctgcggcgta
    10861 ttggttatcc aacgttttga gttgatcgat caattctaat gttacgatct ccccaccata
    10921 acttttcaat cctttttctg gatcattttc gttgaattct actcgataga aatgatcgtt
    10981 ttctttctcc ttcaaagaat cagttggcgc agcctcttca agtaattcac gaacagctgc
    11041 tttttcctct tccgacgtgg cttggtattt ttttgattcc tcaaatcccc cgttttcatt
    11101 cagttctaaa gcaacttttc gatagtcttt caaaaaataa atggttggat tttttttcca
    11161 ttgcgtcact cgtccgctgt caataattgc ttgtacttca ggaagaagat tttcttttcc
    11221 tttttctgat ctttctttca gctgttctaa tgtttccaat ttccgttggt attttcggat
    11281 cgtagcggct gaaaaagtcg attcaccttt ttcaaagcgt tcgatttctt ctttgattct
    11341 tggaatattt tcgattgtca tatccaggcc gccgtacttg ttatagccca tttcctttag
    11401 ctcttcttgt ctttcaagtt tttctacctg tttttcttgt tgcttgatct cttctctcag
    11461 actatgcact ttgttttcta aacgttcttg ttgcctaaac caagaatgcc catttctctt
    11521 atcgttcatt ggctgaccgt tggtctttct ctggtgttca aacatcttct caatttgttc
    11581 gtttaattca ttttgcaatc gtactaattt tcttttggat tttcccaagc gactattgtc
    11641 tagtggttct ttttcttctg ccatgtccg
//
LOCUS       DARBDN010000081        11473 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000081 DARBDN010000000
VERSION     DARBDN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.082"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(75..620)
                     /locus_tag="SCH06_002161"
     CDS             complement(75..620)
                     /locus_tag="SCH06_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEG1078704.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(632..1324)
                     /locus_tag="SCH06_002162"
     CDS             complement(632..1324)
                     /locus_tag="SCH06_002162"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEG1078705.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1343..1627)
                     /locus_tag="SCH06_002163"
     CDS             complement(1343..1627)
                     /locus_tag="SCH06_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078706.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1640..2203)
                     /locus_tag="SCH06_002164"
     CDS             complement(1640..2203)
                     /locus_tag="SCH06_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEG1078707.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2431..3093
                     /locus_tag="SCH06_002165"
     CDS             2431..3093
                     /locus_tag="SCH06_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HEG1078708.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3217..4413
                     /locus_tag="SCH06_002166"
     CDS             3217..4413
                     /locus_tag="SCH06_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEG1078709.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4514..5890)
                     /locus_tag="SCH06_002167"
     CDS             complement(4514..5890)
                     /locus_tag="SCH06_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1078710.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5927..6793)
                     /locus_tag="SCH06_002168"
     CDS             complement(5927..6793)
                     /locus_tag="SCH06_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HEG1078711.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6882..7907)
                     /locus_tag="SCH06_002169"
     CDS             complement(6882..7907)
                     /locus_tag="SCH06_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1078712.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7925..8599)
                     /locus_tag="SCH06_002170"
     CDS             complement(7925..8599)
                     /locus_tag="SCH06_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078713.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8783..9676)
                     /locus_tag="SCH06_002171"
     CDS             complement(8783..9676)
                     /locus_tag="SCH06_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEG1078714.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9750..11447)
                     /locus_tag="SCH06_002172"
     CDS             complement(9750..11447)
                     /locus_tag="SCH06_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEG1078715.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLAKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
BASE COUNT         3395 a         2520 c         1969 g         3589 t
ORIGIN      
        1 aaaacaaagt cgtttgtttt atgctcttct tttattattt tgtgcttttt attttatcaa
       61 atcactttgt ttttttataa aatttctgcg cctagtgtgg actcaaaatg tctcaatgcc
      121 cattcatgtc caacgggatc gaaacttgcc acggcatctt tgaaaatatg gagtttgtat
      181 cctagattat acgcatcgac tgctgtatgc aacacacaga tatctgtaca tacgccggtc
      241 aaataaatat ctgtgatctg gcgttctcgc aaacggatgt ctagatctgt tccactaaaa
      301 gcggaataat gccgtttgtc tatccaataa acattttcct cttgctcata gtcttggtat
      361 aaacttttta aagagccgta caattcccgt ccacccgttc ctatcacatt atgcggagga
      421 aataagcggt tctccggatg aaaggaatct tttggatcat gcgcatcaat ggcaaaaacg
      481 acaaaatcct tttgatcaat aaacttcttt gtatgagcag tcagcttttt ttcaattact
      541 tgtcctgctg tcccagtagt cagctttcca tcctctgcaa caaaatcata tgtgtagtca
      601 atcgagatca atgcgttcat cttagtcctc cttatacgag atgtttgaca aattcgatca
      661 ccatttctgc tgatcgtttg cctgcgtctt cgataaattc gtcaaagctt tgtgtcgccg
      721 agtgatctgc tgtgtcgctc attgcacgta cgatcaaaaa tgggatattg aactgacgag
      781 ctgtttgtcc aacagcggct ccttccattt cgcaagctaa tgcttcaggg aaattcgtta
      841 agatttcttt gattttatct ggcgagtcga caaatgtatc acctgtaacg atcaatcctt
      901 cttttgcgtt caaattcgtt gcttttgctg ctttaaccat ttcactgcgc aaatatgtgc
      961 ttgcttcata atatagaggc attcctggta attgtcctgg tttgtagcca aatcctgttg
     1021 catctgcatc aaaataagct actttgtctg atataacgat gtcacctact tgtaagcctt
     1081 caccgattcc gccagctgaa cctgtattga tcaccatgtt cacgccgtat tgttggatca
     1141 acagacttgt ggtaatagat gctaagactt ttcctatacc ggaacgtacg acgatcactt
     1201 cgtggttacc taatgaacct gaaataaata aagcgcctgc gcgttcccat gataatggtt
     1261 cgcttaggtt ctctctcaaa atttttactt cttcttccat tgcgccgata ataccgattt
     1321 tcatcttttt aattccttct ttctatataa atgcgattgc taaaaaaacc acacataaca
     1381 ttaggataac aataataaga gatttcatca aaaaagagtt ccatttggtc gtcttttccc
     1441 gttcgctgat ccttgttttc gtgattggtt tattcttttt gctttcttta cgataaaagc
     1501 tggcaatctt tttttcttct tgctgataag ctgtttctgc ttttcgctgt ttttttaatg
     1561 actcgcttgc ttgtgcttgt tgtcgcttgc gaagttcgct tcgcgtaata agcggtcctt
     1621 tggccataag ccgatccctc tactttcctt tggtcaatag ttcccagtat tgaatcgcat
     1681 aaatcgtctt tgcatcacaa atcaactgat ctttcatcgc ttgttgcgcc tcttcaagag
     1741 ttagatgata caactccagt acttcgtctt catcttgtgc taaaggattc tcgaccttct
     1801 ctaccccttg tgcatgataa atatgaagga cttcatttgc aaaacctggt gaaagataca
     1861 tcgaagtaag atggctcagc gacttcgcac gatagccagt ttcttcttct aattctctag
     1921 ctgctgtcat ttcgggattt tgtccttctc ctggatcgat ttttccagct ggaatctcca
     1981 aaatcacttt ttctaaaggt tttcgaaatt gtttgacaag aagcagacga tcttgttcgt
     2041 caaaagcaat gatcccgaca ccaccaggat gaaataccag ttctctcttc gaagttcctc
     2101 catctggcaa acgaacttcg tctacagcaa catcaataat ttttccgcta tagatttctt
     2161 tgcgactgat tgttttttct tcaaattgct cattgttcag catatcttct cctgctttct
     2221 ttgtaatcat aactgctttt ttttcatttt tcaatttttc tcaaaaactc cttattagtt
     2281 taccatagat aaaccttaga ttttctctaa atatagaaaa tccttcttta gtccgatact
     2341 ctttctagta gtccgtatgc taaaataagt atgtaatcga ataacgaaaa gaattcaata
     2401 ctcaacgata aatgacatgg agggtttatt atgataaaac gaaattggcc gtggcttcta
     2461 gcattggtct tgctatttct ctttgtccga aacaatagtt tttcttttgt tctaggactt
     2521 ttattgatag gtgtagtttt agttttgtgg ggactctttg gttcgcgcag gaaaaaggga
     2581 aaacaagaag aaattcctgc actgactgac gaacttgaaa ctcactatga aaaaagcggt
     2641 atgacagcga atgaaatttc attttttcga caaacaatga atcaaacaaa aaatgagatc
     2701 aatcaattgc aaatgaatat gcagcagaca gccaaactta aagcaatcga tctccgccat
     2761 gatccagtca aagcagcgaa agctttattc aaagaattgg tgaaagaacc aaaccgactg
     2821 catgaagcaa gtcagtttct ttatacgcat ctgccgaatc tagttgattt gacaaataag
     2881 tataatgaga tcaatgacca tgagatcaaa aacaaacaga cctatgaaaa actagaagaa
     2941 agcgcgcaga tcatcgacca gctgtcagct ttaatcgcac aagattatca aaaattcgtt
     3001 gctgaggatc tagatgatat cgacgtagag atatctgttg cgaaacagag cttaaagcgt
     3061 gataataaat atgaaccaga acaaaaggat taactctttt gttcataaaa gaagactcgg
     3121 aacattcaga tgatgtctgg ctgtttcgag tactttttct aaagtagaga cattcatgta
     3181 agaatcgaga acagattcaa caaggaggaa ttttttatgg atcataaacc gactgaaaca
     3241 aaagatgtta caccagttaa cgatacactt gaagatttat tgaacaaccc gttttcaact
     3301 ccaacagata cgctgaccac ttcacaacaa gcggagattg atcagctcca agagcaacag
     3361 acagctgctc gtttaattga caaactaccg gcggaacgcc aagaacaagc taaacagcta
     3421 gcagcaaaaa tcgatgctaa tgatgcacag tctgtcatca gctacggatc ggctgcccaa
     3481 gcaaaattaa gtgaattctc acaatcgatg ttgaatcatg tgcaagcaca agatattggt
     3541 cctgtaggag attccttaac tgaactgatg tatcgtctcc aagaagccaa tcctgacgaa
     3601 ctgcgtgccg gagaagggaa catcttccag cgtgtcttcg ggaaggtcaa acaatcgatc
     3661 tatgaagtga cagcaaaata tcaaaagatt ggtgcacaaa ttgacaagat ttcagtgaaa
     3721 ttagataaag aaaaagacgg tctgctaaaa gataatctga tgttagaaca gctttaccag
     3781 aaaaacaaag actactttga tgcactgaat atttatatcg ctgctggaga attgaaaatg
     3841 gaagaacttc aaacaacgat cattccagaa gcgatgaaaa gagcagaaga aactggcgat
     3901 cagatggatg ttcagattgc caatgattac acgcaattcc tagatcgtct ggataaacgt
     3961 acgcatgatc ttcgcttagc tagacagatc acgatccagc aagcaccaca aatccgtttg
     4021 atccaaaaca caaatcaggc cttggctgaa aagatccaag catctatcgc tacagccatt
     4081 ccgctgtgga aaaaccaagt cgtgatcgca ttgaccttgc ttcgtcaaaa agatgcagta
     4141 actgctcaac gccaagtctc tgaaacaaca aacgacttat tgaagaaaaa ttcagaaatg
     4201 ctgaaaatct cagccatcga aacagcgaaa gaaaatgaac gtggaatcgt ggatatcgag
     4261 acccttcaaa ccactcaaaa tgatttgatc gaaacaatcc aagagacatt gcgtatccaa
     4321 aaagaaggaa aagaaaaacg tcgtcatgca gaagtagagc ttggacacat ggaagaagat
     4381 ctgaaacaaa aactgttgga tttaacccaa tagatcacct ttcgcttgtt actaaaacaa
     4441 acgcccaaca acagtttatt acaactgttg atgggcgttt ttcttatctt tcttctaact
     4501 tctccattgg agtctatttc tcattcatct tgctgtgtcc atagccatag ccaaaataaa
     4561 tgatcagtcc aataaccatt acgataccga acacgatcca tgtcacagtt tgcagacgaa
     4621 gcatcaatac aatacaagtc aagatggaga cgattggcaa tagcggaacg aatggcactt
     4681 tgaattctcc agcttttggt ttgccaaaca tttttctcaa cttcagtaag cctagactaa
     4741 caagcatcaa ataggcgagc gccatgatat tcgttagttc cgctaataca ttcaatggga
     4801 aaaatccggc aaagaataca gctgccacac cagcggcata agtcgctttt ttcggtgtac
     4861 gatgcttttg atcgatttct gtcataaact taggaagtaa gccatccttg ctgacagcaa
     4921 acagtaaacg agcaagtgaa tacatcatcg agatcgttac cgtcagtagc gttaaaattg
     4981 cccctacagc gatcaccgcg cccactgttc catgtcctac atacctcatt gcaaaagcca
     5041 ctgggtcatt gactcctagt tcagtatacg gaacgattcc tgtcaagatc agcgtcacga
     5101 tgatgtaaag gacagtagca atcagtatcg aaccaatgat tcctcttggc acatcttttt
     5161 gcgggttttt gacttcctcg gctgccattg caacggcatc aaatcccaag aaagcaaaaa
     5221 acacaagagc tgcaccatct agcacaccgg aaaaaccaaa aggcatgaat ggctgccagt
     5281 tatcaggttt aacgaaaaat attcctacaa tgataaacaa cgcgatgata ccaaatttga
     5341 catataccat ggcattattc aaacgtaatg ctttcttggc ttcaagcgac acgatgtaag
     5401 tgacgaatat cactacgagc accgcaatca agtcaatgta tgtaccattt tccggattgt
     5461 acccgccagt taatgcttgt ggaagttcgg cccctaaact tttcaaaaaa ccttgcatat
     5521 agccagacca tccggaagca acagaggaaa ccgctagtaa aaattccccg atcaacaacc
     5581 accctgtcag ccaggcagca aattcaccaa atacaacata cagataggca tatggcccac
     5641 caatcactgg cactcgcgaa gcaaattctg cgaaacttag tccagacaaa atgacaacga
     5701 ttgcagctaa gacaaatgaa agtgacagtg ctggaccagc attttgattg gccgcaaccc
     5761 ctgtcaccac aaatattccc gtaccgatga tcgcaccaat tccaagcatg atcaaatcag
     5821 acgtttttag ttcttttttc atctcactcg tatgattgag attgatctct ttcttacgaa
     5881 acaaatccat tgaagttcct ccccatttta ggttggaaaa cagcgattaa actgttttca
     5941 tataccctaa aaggatacca cctaaaatga ctaaaaggca accaacaata acataaatga
     6001 gctctttttt cgtttttctt tcgccaagga tgaaaatccc acctaaagta gagataatga
     6061 tccccatttg tgaaagtgag aagccaacag ctaaaccaag tgatttgact gttagaagca
     6121 tgcagatgtt tcctaagccc cataataatc cacagatcat gtttttccac acaaactgat
     6181 cgactttaac tttacggaaa gcaaagaagc ttgcgcctaa gatcattccg atactttgag
     6241 gtaagataat tgacatcgca tccaaattcg cccagttgac gatgatggta tatacaccat
     6301 aaccaatcgt agagaagatc aatgctctaa aacccttacc aaaatcaagc attttattat
     6361 ctgtatctat ttttccttcg tcatcttgtc gggcagtcaa atacgcaccg cttacaagaa
     6421 gagctaaagc aataataccg tatacataat ctttcgtttg tgtccattca tggaagaaaa
     6481 cggctcccgc aatcgtattc aaaattaatt gaaaaccagt agacaatggt agccctacag
     6541 aaacacccat gtacttcatt ccatggaact gtccattttg tccaacactc caagctaagc
     6601 cggataaaaa tccgatcaag aaaatccaag gggtgattac aggactaaca acgaaaaaga
     6661 caactaaaga aaacagaaat gcaccgatcg tcattcctag tgtttgttga ttggcatcgc
     6721 caccaatttt accacttact aaaccaatac taccccatgc caacataggg actaatgcta
     6781 ttaaaatttc cataaccaat ctccttttat ttcacatgat aagaaactta tcagcgaaaa
     6841 cgttaacaac acaagcactt tttttcgttt ctaacgattt tctaacgttt ttcattataa
     6901 aaatttaaga ttgggaaaaa taaagtcatt gttgtccctt ttccttcagt tgattcagcc
     6961 gtcaaatgga tacctaattt ttcggccaga ttttttgcta aataaagtcc taatcctgtt
     7021 gaatgtgttt tgctaagtcg accatttctc ccagtaaatc ccttatcaaa gatccgtttc
     7081 aagtcttccg ctgggatacc gatccctgaa tctttaactg aaaggctgac tccttgcgct
     7141 tccttttcta tgctcacaat gatgtttccg tgatccggcg tatatttgat ggcattacta
     7201 agcaattggt tgaagataaa agcgatccat ttagcatcgg tcaaaacagt atgatcctca
     7261 ccaacgatct cgtagcgaat atttttttgg ataaaataat ttgcctgact gcgtatcaca
     7321 ggctgaatga ttccttttag tccatattct tggatgaggt agtcccgcga gaaactgtcg
     7381 agtcttgcat aatacaaaac ttgttctacg tattcatcga tttttgataa ttcattttct
     7441 agtaatgtat acttttgatc gtcaatatcg aactcgatcg aacgaactag caatttagaa
     7501 gcggaaagtg gcactttgat ttcatggacc catgagtcaa tataatcttt ttggtcttgt
     7561 tgattactga ttgctgattg cattacttct tggtgttcac ggatcagctg attgatatat
     7621 tcttctacca gtttttcttc ttctgtcctc ccaccactca aataattttg caaaggggaa
     7681 gttttttgta tgtcggctaa ttttccccac catcttctct tgctcaagta accacccagc
     7741 agataaaaaa tcagaaagac gccctcaatc aaagctaaat aagcaattgt gctcaaatca
     7801 actttgatgt ttggcgccag ccacatcaca aagatcgtca atgcaataaa aaacagccat
     7861 cccaagatca atgtccactg atctttcaaa tatttaaaaa aattcatctt aaccgctcat
     7921 cctttcaggg aacgatatat ccctgtccta cttttgtttc gatatatcct tggatacctg
     7981 cctgttcgat ttttcggcgt aaccgattga tgttgactgt caatgtattg tcatctacaa
     8041 atcgttcgtc atcccacagt gctcgcagca atttttcccg acttaagatc tttccattgt
     8101 gcttcatcaa aataaataat agacgatatt catttttgct caaatcaatg atctctccgt
     8161 tgatttccat acttccgttg tcaacattca acgtaatgcc attgtggctc atcatttcac
     8221 tagataattc tgtgtagttg taagaacggc gaagtaatgc attgattttt gcaatcagta
     8281 catcgatttg gaaatgtttt gtcacaaaat catctgcccc catgttcata gccatgatca
     8341 tatccatatt cgtattcctg ctggagataa aaatgatcgg tactttcgat acttcacgta
     8401 ttttttgaca ccaataatag ccatccaaaa cgggaagatt aatatctagt aatacaagct
     8461 gtggttcttc tctttcaaag tctgagaaca cttgattgaa atcggtcgtt ccaaaggttt
     8521 caaattgcca tttctcaagt tcctccatga tcaattgtcg aatgatctct tcgtcttcga
     8581 ctaccatgat ttttgccata aaaaatccct ccatctttct tcttgctact acaatatcaa
     8641 agaagccctt gtgaaacaag ttggcttacc tggaaaatgt cattttagca aacgttaaaa
     8701 aaaactggaa atatgcgatt taatcgcgtt tgtctcttcc aagcagctta aatttattat
     8761 gttattctta ataattggtc tattatctgt tatttttctt tcgttgtttt tgtcttttaa
     8821 attttcgata acaccaataa ccgaaaagcg ttagcactag caatatacct agaaggagta
     8881 taagtaatcg ataaagatgg tatttttttg tctgttctat ctttgaagag acttcttctg
     8941 taaagggaac tcgtcttcct gtcactagta atcggtgagt gttcacggtg taaggtgtac
     9001 aagtgataag tgtgactaga tcctgctttt ctctaattgc taatgtattt gtttttgttg
     9061 gaaggacaac aattttctca acgacttcat aagcgagcat ccgaccatac acttcaagat
     9121 agaatcggtc atcttgctcc atttcttcaa gatccgtaaa gagttttttc tcagcaatac
     9181 cgctatgggc ggtaatcacg gaatgtgtac tctctcctcc agttggaaaa gaggtgcctt
     9241 gcaggactgt cgctcctcta tctaacaaaa gatcattcgt ttcatcaaat aaaggcaagc
     9301 taacattgat tttcggaata tagatggctc cgatcatatg ttgttcgtaa tattcttttc
     9361 ctggattttg gacatttcta accgcttgct caaaaggatc tttgacttgt cccattcctg
     9421 ggattactga tgtatgagca agcgtctgat ttttcttttc atgcactgct aattgttgct
     9481 catgtttttc ttctttatcg cgttcaagct gcttttgata attctcgatc cttctttgat
     9541 ccaaataatt gctgagagca tctgctaaaa atggatatgt aaaaactgca gctccggcaa
     9601 gaaacatcac tgccataaat aattgtaata aaagactgat ttgggtttga ggtctattac
     9661 ctattttctt tttcattttc ttcaccttct tatttaaaaa aactgcagca acctttataa
     9721 aaccgattgc tgcagcttat ttttgttgct tatacttcag acttcatttt agatttacgg
     9781 taccagctgt acgctccaat catcaaactt attccgatta gtaagaatgc caagagcccg
     9841 ttcccaccag tagcaggaag tgacccgcgt ttcatattcg gtactctttc tggccctgga
     9901 ttttctactc ctacgatctg aatttcttca ttatagcttc cataagagat gataaattca
     9961 gtaaaggctg cctcacctgt tggaagtaca taaccttctg gcgccatggt ctctttcatt
    10021 tgataggttc cataatctaa cccttgaacc tcaaagtatc catttccatc tgcgacaaat
    10081 tctgttgctt gtccgcttgt tgcccactca attctatctg ctcctgattc ataaacagct
    10141 aaaggcgact cccctttata aaatattgcg tattcagaac ggtcttcatt ccacaattcg
    10201 aatcttgcat ctttaagcaa ttcactgctt gatgcatcat atttttcaaa ctttcttcca
    10261 cctgttgtga ctttctctgg cggctctact ccttcttcat aatcaaattc atcatttcgt
    10321 ccgatttcaa taaccgctgt gttgttatgg aaatcatccg cttctagttc tgtggaaacc
    10381 ttcaaattat acgtgatcgt taaatctcct ccacgtgcat ctgctaatct acctaaagta
    10441 tctactttgg ctactccatt ttcttctgtc aaaatcgtca cgacaaaccc gttgcttact
    10501 acttctacta tataatcttg tccttttgtt aaaatcgtct cgccggctcg cacttctatt
    10561 tcctgatcat aataagttag accaactgta ggcgtatctg tgattttgta atttttgata
    10621 acagcgcttc cgttttcaag gacagaatcg atgaaataag gaataggtgc tgtgatcgtg
    10681 taagaagccg tttttcctct ttctagatca atataagaaa tcgtttcttg ttctccagct
    10741 tcattaataa tcgttacttg tctaaggtcg ctttcctcta cattcatctg tttatctgct
    10801 tctctgattt cgtttttcgg atacaaatgc acatctgtat tgtatgtgtc tttccatgta
    10861 gaaccatccc acacgccatc caccatatca ggcatcatca ctggcatcat aacaaccatt
    10921 ggagacgcga ttctggaaat atgagctggc gaataagttt ctaagaaaag atagacttta
    10981 tctctagaag aaggtgcttc ttccgtcact tggacggtag agaataccgc ttctccagct
    11041 tcattcgttg tttgtttgtc aatacttgtc agtcgatatt ttaaaaacca actttctgtg
    11101 tgccgttttt gaatccattc aatcgcttcg gcagaattaa gaccgtcttc tcgttccggt
    11161 gttaaaggat tatctcgaat caaatcgtaa tatacttccg ttacgtcaaa caaatcaaaa
    11221 tcgactcctg gaatattttc ttcaccaaaa tccgtagaaa ccaatccgct attcggtcgt
    11281 tcttccggaa cagatgagaa accttttttg tgtaatgtaa tcgtcacttc acttggtttt
    11341 tgtgcgactt cttcggcttt ggctagtttt ccgttcccga aaatccctat tcccgcagta
    11401 acgagtaaca gtacactcat tcccgtgaca atcatttttt tattcatttt tttctccccg
    11461 ttcttttttt att
//
LOCUS       DARBDN010000082        11471 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000082 DARBDN010000000
VERSION     DARBDN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.083"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            4..189
                     /locus_tag="SCH06_002173"
                     /pseudo
     CDS             4..189
                     /locus_tag="SCH06_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347581.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
     gene            763..1026
                     /locus_tag="SCH06_002174"
     CDS             763..1026
                     /locus_tag="SCH06_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078716.1"
                     /translation="MFIKYGADTVATMFTEEYQVDYYEVIDKCVHFVYEKVWNFMNFA
                     ISEEILRVQENRTGIFTRDRKLNLIAHYIRNRWSSIPNFNYKK"
     gene            1360..1731
                     /locus_tag="SCH06_002175"
     CDS             1360..1731
                     /locus_tag="SCH06_002175"
                     /inference="COORDINATES: protein motif:HMM:NF016724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEG1078717.1"
                     /translation="MWLSDEKIQWRSYQKRILTNFATYLNNNSVHLVAPPGAGKTFLG
                     IEMIRRLDCKTLILVPSLILKKQWLTTIEEYFLVNPADSCYLSGAIEHPSHITVETYQ
                     TIYNRLKEEPTYGDQLELLVF"
     gene            1911..2333
                     /locus_tag="SCH06_002176"
     CDS             1911..2333
                     /locus_tag="SCH06_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078718.1"
                     /translation="MVKEEVLCPHQDFLYLIPANQETTQHYFTFLEKQNELVEALMES
                     QETVDYLLSLEFVQHPLEHSKEIYENFELFTSALIYLNHHNYELIPEHWQLLGSSKQQ
                     GKKASVPSLGKKELITIYQQMFEDQPELPIFYQLKKAG"
     gene            2478..2723
                     /locus_tag="SCH06_002177"
                     /pseudo
     CDS             2478..2723
                     /locus_tag="SCH06_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2832..3788
                     /locus_tag="SCH06_002178"
     CDS             2832..3788
                     /locus_tag="SCH06_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078719.1"
                     /translation="MLILANQASTFVQTQQLRGRGLRLGAQNKVTNIWHLAIGLPGVP
                     LSEQPDLKRMLRRLGNISGLTFESSPKIESGGDRFALPLEYTTTTMETYTQSMFYFSC
                     ERSRLKEQWSTALADGWHLSMPIVVRKVDQVKQKQETSLPIVVKNIEPLSFWSAIFKG
                     NLLEYFQIRRRQKLWEKECARKKSLAICVQTTLQRLGEVSDRKVIVAADQQEFRCYLE
                     NAGYREGQLFTEAMRELLAPLENPRYLIEGKKIVLTVPERFGRNKQIANLFLNELNQS
                     SLPKCQLVYTRNPEGRQKLVTYRMRQVFQTRDEVIIQKNIWT"
     gene            complement(4624..5295)
                     /locus_tag="SCH06_002179"
     CDS             complement(4624..5295)
                     /locus_tag="SCH06_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1078720.1"
                     /translation="MTIKTSLQNQAYQSIRQQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRHQGLVDTIPQSGNYISLIDLDLAKNARFVREHLERQIMLECCAKMNNQ
                     KKQVLETIIAEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLEDNNTHLERF
                     RWLRVKTEGLKWEKIMEQHHQLFKALTMQDPEEANFLTSLHLHLMLDEQNVVLTTHPK
                     YFKNI"
     gene            5612..7243
                     /locus_tag="SCH06_002180"
     CDS             5612..7243
                     /locus_tag="SCH06_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEG1078721.1"
                     /translation="MVLIKDWQDSIEGLNKMQVQLPYFNVEAVKQEGQKHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELESGVVVCETFDEEVVEKAYHDYNNDILEIVMGEDGEL
                     KKRLLAVTADSLYCNPKNITDYQRVVKYFEDPTLQFTTFTITEKGYSLKDSKGQFFSV
                     VEADIKSGPTNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFMIAE
                     AWQKKGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSESVKMDLLKAGFEDLDIIHTA
                     KNTNIAAFTNTEKVHYLVIEDSFPNGRPKLEAAGVIMTDRETVDKADIMKVTTCLNPL
                     HTALAITGCLLGYKSIQAEMQDDDLVGLIKGIGYVEGLPVVESPGVIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGKNFVPSPDPLLVELQEKFSVLKLGEQDPAKIHCAVQEILENKEIFGLDLYQ
                     VEIGKKIEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            7246..8325
                     /gene="uxuA"
                     /locus_tag="SCH06_002181"
     CDS             7246..8325
                     /gene="uxuA"
                     /locus_tag="SCH06_002181"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEG1078722.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKALKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYHLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEAKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLEWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            8399..9826
                     /gene="uxaC"
                     /locus_tag="SCH06_002182"
     CDS             8399..9826
                     /gene="uxaC"
                     /locus_tag="SCH06_002182"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEG1078723.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAEHQPIIDYHCHLDPACLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGAGNDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLKMMDVKAICTTDD
                     PTDDLRYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAGIPIKNFNGL
                     KQALSQRVDYFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIESRK"
     gene            9910..10557
                     /locus_tag="SCH06_002183"
     CDS             9910..10557
                     /locus_tag="SCH06_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEG1078724.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINAITAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVEIIKLFPGSAFGPSVVKTYQAPLPYVNIMP
                     TGGVSLDNLEEWFEAGVVAVGVGGNLLAPVEKGDFEEVTRIASKYIDKFYEIKNY"
     gene            10686..>11471
                     /locus_tag="SCH06_002184"
     CDS             10686..>11471
                     /locus_tag="SCH06_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1078725.1"
                     /translation="MERKFGLRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     TVGTLFLVARFIDAVTDITMGRIVDGSKPSKTGKFKPWILRMSGPVALASFLMYQTSM
                     ASASMSIKVIYMYVTYILWGSIFYTSINIPYGSMASAITSVAEERTALSTFRSIGATL
                     AGMFIGVLTPIFIYTRDSSGAQIVRGGSTFTIVAGVFSVCAVICYVICYKLTVERVKS
                     DESQLKVSLLKSLKGLAKNRALLSIIAAAIFLLLAQLLTMSMNN"
BASE COUNT         3910 a         1627 c         2300 g         3634 t
ORIGIN      
        1 gaagtgattt tattgatttt gtctctcgta ttactagttg tatctaatct aatgaaaaat
       61 aatcctccta caaaaattaa ttctttttat ggctttagaa ctaaaaagtc aatgaaaaat
      121 gaaaaaagtt ggcatttagc acaaaaattg ttgggggatt tttcaaaaaa aaaagttatc
      181 ccagtatttt tgatgggtat tgtttttttc agtatagaga tttatagttt agctatttta
      241 aaaaatgaaa attttttcgt tagtgtatta atgggtgaaa gtttaatcct aatactgatt
      301 ttgtgtttaa ttgttcatga agtgaataaa caattgtgaa ttaaaaaaat aaaaacctag
      361 tataatcact ttaataaatt gttggtagaa ggtgatcaaa atgggagtaa acgaaatgat
      421 gaaagtcaga ttgagttttt aaatgatacc ttcctcagaa cttcaaaacg aattcaaaga
      481 ttcgttgaca aatcttgagc aagatcattt aaaaaaatat tttctcttca tttgacgaaa
      541 aatgtttaga aatcttatat aagtgaagat aaagtaattg gtgtaattaa ttgtagagaa
      601 tagcctttga gcaattgaag cgatacaatt atttagaaaa tgaacttcct ccagcatact
      661 acatgattcc ttacgggacg atgttaaaga agaaagcaag aaattttaga agtattagta
      721 gataaactaa tgggcttttc tcaatttaag ggagtagccc aaatgtttat caaatatggt
      781 gcagatacag tagcaaccat gtttacagaa gaatatcaag tagactatta tgaagtaata
      841 gataaatgtg tacattttgt ttatgaaaaa gtgtggaatt ttatgaattt tgcgataagt
      901 gaagaaatct tacgagtaca agaaaacaga acaggaatat ttaccagaga cagaaagctt
      961 aatttgattg cgcattatat acggaatcgc tggtcatcaa taccaaattt taattataaa
     1021 aaataattat gaacaatctt ttatacaata tacacaataa atcaagtagt atttatgaaa
     1081 aaagacttca aaaacagaat gattttctat cagtcttaga aattatagag ctaaaaattt
     1141 tggtcacgcg tagaaacgcg ttttttttgt ttttttgata gtaaagaacg tacaaaacaa
     1201 tgagaattta aaagattgta ctaccagttt ttttaccttt tcatttgagt ttagagtaag
     1261 taaaatatta ctataaaaac acatattctt gaagaaatct tttttttgct gtattcattt
     1321 agattatgat agagaaaata cgtgagaggg ggacctggga tgtggctatc tgatgaaaaa
     1381 attcagtggc gtagctatca gaagcgtata ttgactaact ttgctactta tttaaataac
     1441 aattcagtcc atctagtggc tccaccaggg gctggcaaga cctttttagg aattgagatg
     1501 atccgacgtt tggattgtaa aaccttaatt ttggttcctt ccctaatatt gaagaaacag
     1561 tggttaacaa caatcgagga atatttctta gtaaatccag cagatagttg ctatctttct
     1621 ggggcgattg aacatcctag tcatattaca gtggaaacgt atcagaccat ttacaaccga
     1681 ctgaaggagg agccaactta tggtgatcag ctggagctgt tagttttttg atgaagctca
     1741 tcatttaaaa aaaagctggg gtgaattgtt gattgacttg aagaaaaaac aaccgaatct
     1801 gttgacgatt tccttgacag ccacgcctcc gattgatagc tctcagacgg agtggaagca
     1861 atatattgag ttaaaatggc ctgattgacg aagaaattag cattcccgag ttggtaaagg
     1921 aggaggttct atgtcctcat caggattttc tatatttgat tccggctaat caggaaacta
     1981 ctcagcatta ttttaccttt ttagagaaac aaaatgagct ggtggaagcg ttaatggaaa
     2041 gccaagagac ggtggattat ttgctttctt tagaatttgt tcagcatccg cttgagcatt
     2101 cgaaggaaat ttatgaaaat tttgagctgt tcactagtgc attaatttac ttgaatcatc
     2161 ataactatga attgataccc gaacattggc agctattagg cagttctaag cagcaaggta
     2221 aaaaagcttc agttccatct ttaggtaaaa aagagctgat cactatttat cagcagatgt
     2281 ttgaagatca accggaattg cctatttttt atcaattgaa aaaagctgga tgattgtttg
     2341 atgagtcgct gcatttgttt ccagagtatc cagacactgt tggtagtcag gcgattcctg
     2401 agaaaaagca agcagtttgt caaattttgt taaaagaaga agttcagctg aagcaagaac
     2461 tgacagcggt cattttgatg gatcgtattt gcaaggaggt attagcaggc agtgatggta
     2521 ccttagctta tggcgtggtt cctttgtttg atgaagttgt tcgtctatta ggtaacactc
     2581 agcaaatcgg tgccatctgt ggagagttct tactgttacc gaaaatgcta gtaactgttg
     2641 agctggcaga actagcgacg ggtatgaatg aacatcctta tatgtcgggt tatttttatt
     2701 tgacggtgga tgacaaaaac cgccaagcat tgatgcaagc agttactcgc ctattaaccg
     2761 aaaagaagtt gaatattttg gtaggaaccg ttagtttgct aggagaaggc tgggattgtc
     2821 ctgcaattaa tctgttgatc ttggctaatc aagcttccac ttttgtgcaa acacaacaac
     2881 tacgagggcg gggcttacgc ctaggtgcac aaaataaagt aacgaacatt tggcatttag
     2941 cgattggatt accgggagtt cctctgtctg aacagcctga tttgaaaaga atgctacggc
     3001 gtttgggcaa tatttcaggt ctgacctttg aatcttcacc aaaaattgag agtggtggcg
     3061 atcgctttgc tttaccactg gaatatacga ccaccacgat ggaaacttat actcagtcga
     3121 tgttctattt ttcttgtgaa cgaagtcggt tgaaagaaca atggagtact gctttagctg
     3181 atggctggca cctatctatg ccaatcgtcg ttaggaaagt cgatcaggta aagcaaaaac
     3241 aagaaacttc attgccgata gtagtaaaaa atatagagcc tctaagcttc tggtcagcta
     3301 tatttaaagg taacttgctg gaatatttcc aaattcgtag gcgacaaaag ctatgggaaa
     3361 aggaatgtgc ccgcaaaaaa agcttggcca tatgcgttca aacgacgttg cagcgccttg
     3421 gtgaagttag tgatagaaaa gtaatcgtag cggctgatca gcaggaattt agatgctatc
     3481 ttgagaatgc tggctatcga gaaggacagc tttttactga agctatgagg gagcttttag
     3541 caccgctgga gaatccgcgg tatttaatcg aagggaaaaa gatagttctg acggtaccag
     3601 aacgctttgg ccgaaataag caaatcgcta acctttttct aaacgaatta aatcaatcgt
     3661 cgctgcccaa atgtcagttg gtgtatacta gaaatcctga aggacgccaa aagctagtga
     3721 cttatcgaat gaggcaagtc ttccagaccc gcgatgaagt aattattcaa aaaaacattt
     3781 ggacgtaagt tgatgaaaat aaattttgct agagtagaac aagtccgaga attaagttgc
     3841 tacttaactg ataatgccaa ggacaggaga atcttttctt gacgactgaa agaaactatt
     3901 tgacttatat aacggtgtgt gatgaatatt tgcaaggcat tctcttaaaa agtactcgta
     3961 atagtttttt tgaaaacaaa acagtacttt attaatagga ctgacagagc gatataagaa
     4021 catctgcaga cagaggtgaa tgcttttctc atgatcgatg aaacaatggt acttcggata
     4081 ttcttgcttt tagtttgaac cgttgtgatt ttctttgatt cctaaaagta gttttataga
     4141 atgaaaatca agcatacgga atgctccttt gattgtgttg tggtgattca atctaatgga
     4201 gcttctatat gtttttttat ttgcaaaaag aaccgataga atatttttat cagtcttaga
     4261 aattatagag ccaagaaatt tcaagcacac ataaaaacgc gtgttttatg cattttatga
     4321 gcaaaaataa ctaaagacca ttacgtaaaa cataggtaaa tcagcattca atctcaaatt
     4381 atgtgatcaa atgttgatat tatttgatta taagttttct tttgctatta tcagtctgca
     4441 aataaacaga ttatagagta tgaatgtaga tagttcaatc tttgtttacg acctcacatg
     4501 tttttttact caagagaaag taatataaag tgactatatt tgacagaact ttacataaaa
     4561 aaagtagtta gttttctgta gtaatcagaa atgtaaataa attaaaaaaa agaaatttag
     4621 cagttatata tttttaaaat attttgggtg agtagtcaat acaacatttt gttcatcaag
     4681 cattaaatga agatgcaagg atgttaagaa gttagcttct tcagggtctt gcatggtcaa
     4741 ggctttaaat agttgatgat gttgttccat aattttttcc cattttaatc cttccgtttt
     4801 tactcgtaac caacgaaatc gttccaagtg cgtattatta tcttccaacc attgccatac
     4861 ttcttcccgt tctgcaattt caaaacaagc tttatgaaat aaattatcat tatgaaaaaa
     4921 actacgagca ttcttttgac taacagcttt ttcttgttct gcaattatag tttctaaaac
     4981 ttgtttcttt tgattattca tcttggcaca acactctagc ataatttgtc gttctaaatg
     5041 ttctctgaca aaacgagcat tttttgctaa atctaagtcg attaatgaga tataatttcc
     5101 actttgagga attgtatcaa caagtccttg atgacggagt tgaatcaatg cttcacgtat
     5161 tggagtacga ccgatagaaa gcgtttcttc caattttttt tctgatactt tttttccagg
     5221 ttctaagtca gcgtagataa tttgctgacg aatagattga taagcttgat tttggagact
     5281 agttttaatt gtcatattta atccctctca aaatttcatt tttgaatttg atattttagt
     5341 tctatgctcg ttatataata tcaaatttca aagtaacata ctagctatta aaaaaacaaa
     5401 aaatactcaa ataagatcaa agagaaatta agctttaatt taagttagtt ctaaaaaata
     5461 tatattggtg tgcttttact aaaaaaagac acaataattc tgacatggta gaaaaaagaa
     5521 tatttttagt tttttcttat tgacagcgat tacattcgat tttatactac aattgtaacg
     5581 gaaactaaca tatcagtatg gaggggtaaa tatggttttg attaaagact ggcaagattc
     5641 tatcgaagga ttgaacaaaa tgcaagttca actaccgtat tttaatgtcg aagcggtcaa
     5701 acaagaaggt cagaaacatc cagtgtggct tcattttggt ggaggaaatc tttatcgagg
     5761 atttcatgca gaaattgctc aatgcttagc agatcaaaat gaattagaat ccggagtagt
     5821 tgtgtgtgag acatttgatg aagaagtagt agaaaaagct tatcatgact acaacaatga
     5881 tattttggag attgttatgg gtgaagatgg tgaactcaaa aaaagacttt tagcagtaac
     5941 agctgatagt ttatattgca atccaaagaa tataacggac tatcaaagag tggttaaata
     6001 ttttgaagat cctacattac agtttacaac gtttactatt actgaaaaag gatacagttt
     6061 aaaagattct aaaggacaat ttttttcggt agtggaagca gatataaaat ctggacctac
     6121 caatcctcaa catacgatga gtattgtgac atccttgttg tatagcaggt ttaatgctgg
     6181 agagttaccg attgcgatgg tttctactga taatttctca cagaatggtc aacgttttca
     6241 agatagcatt tttatgattg cagaagcttg gcaaaaaaaa ggatacgttt ctgaaaaatt
     6301 tattgcttat ttaaaggata aagaaaaagt gacttttcct tggagtatga ttgatagaat
     6361 tacgccaaat ccttcggaaa gtgtcaaaat ggatttattg aaggcgggtt tcgaagactt
     6421 agatataatt catactgcga aaaataccaa tatcgctgct tttaccaata ctgaaaaagt
     6481 ccattatcta gtcattgaag atagttttcc aaatggtcga cctaaactgg aagcggctgg
     6541 tgtgattatg acagatagag aaacagttga taaagcagat atcatgaagg ttacgacatg
     6601 tttaaatccg ctccatacgg cattagcaat aacaggttgt ttgttggggt ataaatcaat
     6661 tcaggcagaa atgcaagatg atgatttggt tggcttaatt aaagggatag gttatgtaga
     6721 aggcttacca gtagttgaaa gtccaggcgt tattgatcca aaacaattta ttgatgaagt
     6781 aatcaataaa cgtttgccta atccctatat tccagataca ccgcaacgaa ttgcaacaga
     6841 tacttctcaa aaagtagcga ttcgctatgg tgaaacaatt aaaaagtatg tcgaaaaaga
     6901 cggaaatgca gaaaatctaa catttattcc tatcgctatt gctgcttggt tacgttattt
     6961 attggcagtc gatgatcaag gaaaaaattt tgtgccaagt cctgatcctt tattggtaga
     7021 gttgcaggaa aaattctcag tattgaaatt aggtgaacaa gatcctgcaa agattcattg
     7081 tgcggtacag gaaatcttag aaaataagga aatatttggt ttagatttat atcaagttga
     7141 gataggaaag aaaattgaaa aaatcttttg cgaaatgcta gtaggtcctc aagcagttcg
     7201 taaaacaatc aataaatata taacagaagt tggaggaaag taactatgga aatgactttt
     7261 agatggtatg gggcaaatga agaaaaaatc tcactacaag aaattcgtca gatcccagca
     7321 atgaaaggaa ttgttggaac attaatggat ataccagccg gagaggtctg gccgagagaa
     7381 cgaattaaag ctttaaaaga tgaagtcgaa gccaatggcc ttaccttgaa agttattgag
     7441 agtgttaatg ttcatgatga tatcaaaatt ggtttgccaa cacgagatca atacatcgag
     7501 aattataaac agacgattcg caatttggca gaatttggga ttgaggttat ctgttataat
     7561 tttatgccag tctttgattg ggtaaaatca gatttggatt atcatttaga tgatgggtct
     7621 tctacgttag cctatatttc aaaaaatatt cctactgatc cagaggaaat tattagaaaa
     7681 gtagaaaatt ctactaataa ttttgaattg ccgggttggg aacctcatcg gttatcacaa
     7741 atcaagcaat tattagaagc ctataaagaa gttgatgaag cgaaattgcg agagaacttt
     7801 gcatattttc tcaaagcaat tatcccgaca tgtgaagaag ttgggattaa aatggcagtt
     7861 catccagatg atccaccata ttctattttc ggattacctc gtattgttaa aaatcgtgac
     7921 gatttagaat ggttgtgtaa tgtagtggat tctccttcta atggtattac gttatgtact
     7981 ggaagtattg cagaacgacc agataatgat gtctatgaaa ttctatctga attttgtcaa
     8041 cgggatcgga ttccttttgc acatgttcgt aatatcaaat atttaagtga taatggactc
     8101 gatttttatg aagcgccgca taaatcagaa tatggttctc tagatatgta taagatatta
     8161 aaaacaatgt acgataatgg atttaatggc tatattcgtc cagatcatgg tcggatgatt
     8221 tggggagaaa ccggtagacc tggttatggg ttatatgacc gagctctagg tgcagtttat
     8281 ttaaatggta tttgggaagc gcttgaaaag ggggcgagta aataattata taatggagtc
     8341 tatttagaag aaaaattttc tcttctaaaa actaagggaa ggaaaggagt gcttaaatat
     8401 gtttttagat aagaactttt tattagagaa tgaaatagct aaaagacttt ttcataaatt
     8461 tgcagaacac caaccaatca tcgattatca ttgtcattta gacccagcat gtttgctaga
     8521 aaataagcaa tacaagaatt tgactcaggt atggttaaat gataaaggag ctggagatca
     8581 ttataaatgg cgattgatgc gagctaatgg gatagaagaa gagttgatca gtggtgcagg
     8641 taatgattat gaaaaatttt tagcttttgt aaaaacagtg gagaaggcgc caggtaatcc
     8701 tatttttgaa tggtctcatt tggaattaca acgttacttt gatattgatt tgacaatttc
     8761 tgagaagaat gcaccagaaa tttggcgacg tgccaacgaa aaaatccaaa cggattccta
     8821 tcgcccaaaa gaattgctga agatgatgga tgtgaaagcc atttgtacaa cggatgatcc
     8881 tacagatgac ttgcgatatc atactgagct ttctaaacag gataattctt tcaaggtatt
     8941 acctactttc cgtccagata aggtctggag tatcaaatca tcaggatttt cgaactatat
     9001 tttaaaactt agtcaagcag cgggtatacc aatcaaaaac tttaatgggt tgaagcaggc
     9061 attgagccaa cgagtggatt attttcatca aattggctgt cgattagcag atcacggttt
     9121 gaatacttat ttttatgaaa tagcagatga aaaaatactc gacaatctgt taataaaagc
     9181 tttagcagga aaaacggatt tccatttatc agaaattgca caatttgtta caggtattca
     9241 attacatttg atgtctgagt atacaagata tggttggacg atgcaaatgc atttaaatgc
     9301 tttaagaaat aattcaagta tattaaagga acaaattgga gtagatgtcg gtggtgattc
     9361 gatgggggat caagctagtt tgacacaaaa tgttgtagca ttgttcgaca ctgctgaaaa
     9421 gagtgggtgc ttaccaaaaa caattttata ttcattaaat ccaaccgatt ggcttccact
     9481 agcaacagca atgcaaagct tccaaggggg tatgattcaa aaaatccaat tgggatgtgc
     9541 ttggtggttc aatgatacag ctgaaggaat gcgtcaacag ttgactacga tggcgcaaca
     9601 aagtttgttg tcgaatttta caggtatgtt gactgattct cgaagttttc taagctatcc
     9661 tcgccatgag tatttccgtc gagtattatg tcaattacta agcgagtggg ttaaagcagg
     9721 tcgaattcca gatgatgaaa tgtatcttag tcagatagtg gagaatattt gttatcgtaa
     9781 tgcgtataat tattttaatt tttttgaaat cgaaagtaga aaataataca aaaaataaaa
     9841 gcttaaattt atttattgta agttagtaca actagctaga gtatgtatcc ataaaagaag
     9901 gagatagata tgaaaaaagt agaaatttta agtaagttag aagcggctgg agtcattgcg
     9961 gttgtacgtg gaaaaaataa agatgaggcc attaaagcaa taaatgcaat tactgcgggt
    10021 ggaattaaag ggattgaact aacttttaca gttccgaatg ctgaagaaat aatcaaagaa
    10081 attgctaaaa aatatgctga tcaaaaagat gtaataattg gagccggtac agttttagat
    10141 gcgtttactg ctcgtattgc aattatggct ggagcagaat atatcgtaag tccatctttt
    10201 gatcgacaaa cagcagagat ttgtaattta tatcaaattc cttatttacc aggttgtatg
    10261 acaattactg agataaagga ggcacttacc gctggagtag aaatcattaa actatttcca
    10321 ggttctgctt ttggtccatc tgttgtaaaa acgtatcaag ctccattacc atatgtaaat
    10381 ataatgccta ctggcggagt aagtctagat aacttagaag agtggtttga agcaggcgtt
    10441 gttgcagttg gtgtaggtgg gaatttgttg gctcctgttg aaaaaggtga ttttgaagaa
    10501 gtaactcgaa tagctagtaa atatatagat aagttttatg agataaagaa ttattaggag
    10561 aaaaaataaa taatactata aaatgtaaaa aataaatact aactctttat acttcagagt
    10621 atagtacgta agttggcagt tcaacagaat gaaaacgctt aacaatagga aggagcgcaa
    10681 attatatgga aagaaaattt ggtctaagag acaaaatagg atatatgttt ggagattttg
    10741 ggaatgattt cactttcatt tttgctagtt cttttttaat gattttttat acaaaagtat
    10801 tggggataag cggagctacc gtaggaacat tatttttagt agcaagattt attgatgcag
    10861 ttacagacat aacaatgggg cgtattgtgg atggatcaaa accatctaaa actggcaaat
    10921 ttaaaccgtg gattttacgg atgagtggtc cagtcgcttt agcaagtttt ttaatgtatc
    10981 aaacatcaat ggcatcagct tctatgagta ttaaagttat atatatgtat gtaacatata
    11041 tactatgggg aagtattttt tatacatcta ttaatattcc ttacggttca atggcatcag
    11101 ctatcacttc tgttgcagaa gaaaggacag cgttatcaac atttcgtagt ataggagcta
    11161 ccttagcagg tatgttcatt ggcgtgttaa caccaatttt tatttataca agagatagtt
    11221 ctggagctca aattgtacgt ggtggatcaa cttttacaat tgtggcagga gtattttcag
    11281 tgtgtgcagt tatttgttac gtaatatgtt ataaattaac tgtagaacgg gttaaaagtg
    11341 atgaatcgca gttaaaagtt tcattgttga aatctttaaa aggattagct aaaaatagag
    11401 cgttgctttc tataatagct gcagctattt ttttgttgct tgctcagctt ttaacaatga
    11461 gtatgaacaa t
//
LOCUS       DARBDN010000083        11118 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000083 DARBDN010000000
VERSION     DARBDN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.084"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            80..1339
                     /gene="lysA"
                     /locus_tag="SCH06_002185"
     CDS             80..1339
                     /gene="lysA"
                     /locus_tag="SCH06_002185"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEG1078726.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1326..2126
                     /gene="dapF"
                     /locus_tag="SCH06_002186"
     CDS             1326..2126
                     /gene="dapF"
                     /locus_tag="SCH06_002186"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HEG1078727.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2129..3010
                     /locus_tag="SCH06_002187"
     CDS             2129..3010
                     /locus_tag="SCH06_002187"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEG1078728.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3007..3723
                     /locus_tag="SCH06_002188"
     CDS             3007..3723
                     /locus_tag="SCH06_002188"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEG1078729.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3729..4424
                     /gene="dapD"
                     /locus_tag="SCH06_002189"
     CDS             3729..4424
                     /gene="dapD"
                     /locus_tag="SCH06_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEG1078730.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4440..5441
                     /locus_tag="SCH06_002190"
     CDS             4440..5441
                     /locus_tag="SCH06_002190"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEG1078731.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5438..6799
                     /locus_tag="SCH06_002191"
     CDS             5438..6799
                     /locus_tag="SCH06_002191"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEG1078732.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6759..7910
                     /locus_tag="SCH06_002192"
     CDS             6759..7910
                     /locus_tag="SCH06_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEG1078733.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7885..9054
                     /locus_tag="SCH06_002193"
     CDS             7885..9054
                     /locus_tag="SCH06_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEG1078734.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9229..10608
                     /locus_tag="SCH06_002194"
     CDS             9229..10608
                     /locus_tag="SCH06_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEG1078735.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10889..11118
                     /locus_tag="SCH06_002195"
                     /pseudo
     CDS             10889..11118
                     /locus_tag="SCH06_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3699 a         1946 c         2494 g         2979 t
ORIGIN      
        1 attattccaa taaaattcaa atctttatca aatgaaattc caataaaaac ggaaaaaaag
       61 tgaaaagagg aatgaaaaaa tgacagaatt gataattggc ggagtcacag caagcacatt
      121 ggcagaaaag tataagacac ctctgtatgt gtatgatgaa gaaaagatga gacaaacgat
      181 gctgtcattc aagcgaggct ttgtatcgaa acgttttgat acaaaagtgc tttacgcctc
      241 taaagcattc caaacgattg agatgctgca tttagttcgt gaatatggat tcgggctaga
      301 tgttgtcagt ggtggggaaa tctataccgc tttgcaagct gattttccta gagatactat
      361 ctacttccat ggtaacaaca agacgccaga ggaactgatc tatgcacttg aaaatgattt
      421 gttgcatatt gttgccgata atttgatgga agttgaatta ttagcagaat taagccaacg
      481 ctatttaaaa aaaatctgta tcatgcttcg gttgaatgtc ggagtagaag cacatactca
      541 tgaatatatc gtcactgcgc atattgattc aaaattcggc atgagctatg aaagtaaaga
      601 gtgccaacaa gcccttcagt tgataaaaga aagcagctat ctagagttag aaggatttca
      661 tgctcatatc gggtcacaaa tttttgatgt tactgcttgg ttagctgaaa tcgacaaatt
      721 gacgaattac ttaaccgatt ttgaccaacc tctttccttg aatcttggcg gagggtttgg
      781 gattcgttat acacaaaatg atcagccgat cccagtcgaa gaggcactaa aaaaactgat
      841 tgaatatacg gaagaagctt tggaaaaacg aaaactgacc attcgtcaat tactgatcga
      901 accgggtaga agtattgttg gagaagctgg tacaacacta tacacgattg gtttcatcaa
      961 aaagacacca cataaaaaat attactttgt agatggcggg atgacagata atatccgtcc
     1021 agctctgtat caggcagaat acgattgtga tttagcagca aaactgtcgg aagaaaaaac
     1081 agagaaagtg acgattgcag gaaaaatgtg tgaatcaggc gatgtggtaa ttaaagaagc
     1141 ttatttgccg aaagcagaat cgggtgatct tttagctgtt tattccacgg gagcttatgg
     1201 atactcgatg agcagcaact acaatcgagc gacacgacca gcagttgttt ttgtcaataa
     1261 tggccaatca agactgattg ttcgcagaca agcattttct gatctactaa ggggggaagt
     1321 ttcctatgat ccttcataaa tataatggct gcggaaatga ttttatctta ttagattacg
     1381 cagaagacac agattatagt caattagccg cttctttatg cacaaaagaa aaatatgata
     1441 cagacggatt gatcgccgta aaaatcgatc cgttggaaat gatctattac aacaaagatg
     1501 gcagccgcgc gccgatgtgc ggaaatggca ttcgctgttt tgctcgatac gtaaatgatc
     1561 agaacatgat gaatgaacag gaattcaacg tagagacatt agcaggcaca agaaaaatta
     1621 cggtgttgga tccctcacct ttttattgca gcgtagatat gggagtgcca gatgattctc
     1681 cggaaaaaat caaagctaat caaacttatc caataaaaaa ccaggaaata gagatcaatg
     1741 gtgaaaaagt aacgatcact agtttatttt taggaacgat tcatacagtt gtttttgttg
     1801 aaaatgcgcg tgaggaagtc tggagaaaaa gaggtgaact gatctgtcat catcctttgt
     1861 tcaaagaaaa aaccaatgtc aactttgtag aagtagtcaa tgaacaagaa ttgatcgtcc
     1921 gtacctatga aagaggagta ggttggacac ttgcttgcgg tacaggttgc tgtgcctctt
     1981 atgtggttgc taaggaaact gggaaaattt cagcagatca ggtagttgtt cacttggaac
     2041 aaggagactt gatgatctct ggtgaggatg cgatacaaat ggctggccca gcagttcatg
     2101 aatggacaag aatattggag gaatgaagat gataaaaggt tcgatcgtgg cgctgatcac
     2161 gccgatgaat gaagagggat cagtagatta tgctggtttg gaaaaattga tccaattcca
     2221 tttagatgaa caaacagatg gattattagt tttaggtaca acaggagaat cttctacgct
     2281 cacacaatct gaggaggagc agatccttca actgacagta aagaaagtgg ctggccgtgt
     2341 gccggtgatt gcaggagctg gaacgaataa tacgaaagaa acgattgaaa aagcgaagca
     2401 ttttgcttct ttgggggcag acgcactttt ggtcatcacc ccttactaca acaaaacaag
     2461 tgatgcagga ctagctgctc attttacagc aattgcagaa gcctcaccga ttccgcttat
     2521 tttgtataat gttccttcta gaacaggcat gtcgattcca atccatgtat tagtaaattt
     2581 agcagaacat cctaatatca ttggtttgaa agaagcctca ggagatatgg cttatgtgat
     2641 ggatgccgct cggttgattg gagaagaatt cttcctttac agtggaaatg atgatttgat
     2701 cctaccagta atgagtgtag gaggaagcgg tgtaataagt gtatgggcga atatccaacc
     2761 taaaatagtc catgaattag taaaagatac gcaggacgga agatggcagc aagcaaaaga
     2821 aaagcaatta aatgcacttg aactgatcca tgccttgttc agtgagacca atcctattcc
     2881 tgtcaaagca gccatgtcat tattagactt accttccgga cctctacgcc tgcctttagt
     2941 ttctctttca aaagagaaaa agaaacaatt agctcagctt ttgttaaaag aaaggacggt
     3001 tgaaaaatga aaatcggact gattggcagt ggacagatgg gaaatagagt cgaagaagtt
     3061 gcacaagaaa gaggagatac ggtccttctt ttacggacgg cacctaaaga agcaactacg
     3121 cttgctttta cggaactgcc agaactgctt attgattttt ctcatccaga taatttagag
     3181 aaaatccttt cgtatagctt atcatatcaa cttccgttag tcattggcac gacaggttat
     3241 acacaatcac agttccaaga aataaaagaa catgccaaac atgtacctgt gatgtatagt
     3301 gctaattttt cgttcggcat catggtgatg aatcaactaa tcaagcaagc agctgcaatg
     3361 ttgcaaggct ggcagatcga actgattgaa aaacatcata gtcgtaaaaa agatgcacca
     3421 tctggtactg caaatatgct gcttcaaaca atccaagaag tgcaaaagct gcagcccgta
     3481 tacaactggc aagggaaaaa aagagaagaa aaccaaattg gtgtacacag tattcgtgca
     3541 ggttctttac ctggtgaaca tgatgtattg tttgctgcta ctgatgaaat atttacgatc
     3601 aaacatgaat ctttttctaa tcgaatcttt gctgcaggcg cagtagaagc agcggactgg
     3661 ttgaaagatc agtcaccagg ttattacaaa ttagaagatt tattaatgga caaaggggtg
     3721 taaaaaacgt ggaagctcaa gaaatcatcc gctacattca aacggcatct aaaaagacgc
     3781 ctgtgaaagt ctatctgaat gtaaccgagc caatcgaatt taaagaaagt aaagtttttg
     3841 gtgaaggaag cagcttcgtt gtttttggtg actatgagac gattgctccg gttttagaag
     3901 ctgaatcaga aaaaatcatt gaaatcgaaa tcgaaactgc tgcaagatac agcgcagttc
     3961 ctttgctaga tattaaaaaa attaatgctc gtatcgaacc aggtgctatt atcagagatc
     4021 aagtgtcaat cggcaacaat gccgtgatca tgatgggagc gattatcaat attggtgcag
     4081 taatcggtga aaacacgatg attgatatgg gtgctgtctt aggtggacga gcgacagtgg
     4141 gcaaaaactg ccatattggt gcaggagctg tcttagcagg tgtgatcgaa ccagcatcgg
     4201 ccaaaccggt tatcgtagaa gacggcgtac tggtaggtgc gaatgcagtg attgttgaag
     4261 gtgtccatat cggaaaagat gcagtcgtgg cagcaggagc agtggtttta gaagatgtgg
     4321 cagcagaaac tgttgtcggt ggaatacctg cacgtgtatt aaaaataagt gatgatcaga
     4381 caaaagaaaa tacagcattg attgctgcgt tacgcgaatt atagaggaga tggagaaaaa
     4441 tgcgcgaaat agatacctgt attgtggggg caaccggatt agtcggccaa acgatgctca
     4501 aagtgttaga agaatatgat tttccagtag gacgattgaa attattagct tcaaaacgtt
     4561 cagccggtaa agtttgtgta ttcaagaaaa agaaacacac tgtacaggaa ttgacagaaa
     4621 cttcatttga aggatatgat ttagcgctat tttctgcagg tgcttctgta tccaaagagt
     4681 ttgcgccaat cgcacgaagt cagggactat ttgtcataga taattcctca gcatggcggg
     4741 aagattcgga tattccatta atcgttccag aggtcaatct ggaagactat acattgaatc
     4801 ggctgattgc aaatccaaat tgttcaacca ttcaagcggt acttccgctt aaagctttac
     4861 aagaagcctt tggtatccag cgagtcaatt attcgaccta tcaagcagtt tctggttccg
     4921 ggcaaaaagg cattgaagat cttcatcgta cgcaaaatga cgaggaacca gttttgtatc
     4981 cttataatat tagccaaacg gtgattccgg aaatcgatca gcctttggaa aatgggtata
     5041 caaaagaaga acagaaaatg ataaatgaga cccgtaagat tctgcatcag cctgctttgc
     5101 cagtatcagc aacctgcgta cgtgtgccaa tcgaaaatgg acatggagtc tctgtggcag
     5161 ttcaactgca aaaagagttt acgacggaag aaattagaga gtgtctcagc cagtttccag
     5221 ggattcaatt agaagatgat ctagcagcac ataaatatcc gacgagcatt cttgctagag
     5281 gaacagatat ggtttatgtt gggaggatca gaaaagacac ttctttagag aacggattgt
     5341 tgttctatac gactgccgat aacatacgca aaggagccgc tgcgaatgcc gtacagattg
     5401 ctgcagcttt aatgcagaaa atagcggagg tggcaagatg agtaatacgc tgaaagtagc
     5461 gaaattcggc ggaacatcga tgtctcatga agagcaattc aaaaaagtcc gtacaattgt
     5521 tctttcagat cccaatcgcc aagtgatcgt tgtttctgct ttaggcaaac gtacgtcaga
     5581 tgatgacaaa gtaacagact tactttattt gatttatgct taccttcagc atcatgttga
     5641 ttggacaccc ctttggaaaa ggatttgtga tcgtttcatt caagtaagag atgttcttgc
     5701 cctgcagtta cctattgaag atgaactagc acgcatacag aaacaactgg aagacgaaaa
     5761 gataactgaa gattatttag taagtagagg tgaatatctg actgctcaac tgatggctga
     5821 gtatcttggt taccagttta ttgacgcaaa agacctgatt ttctttgact atgatgggaa
     5881 aatcgatcag gaaaaaacag cacaggaaat cacaaaagca tttaaaagat atccgaaaat
     5941 ggttgttcca gggttttacg gggcgaaccc tgcaggaaaa gaaaaattat tgggccgtgg
     6001 gggaagcgac attaccggcg cgatactggc gaagatgttg caagcggaaa gttatgagaa
     6061 ttggacggat gtttcaggaa tcatgatggc tgatccgcga atcatcgatc atcctaaaat
     6121 catcgaggaa atctctttta gagaactgag agagatggct tatatggggg ctaacgttct
     6181 tcatgaagca gctgttttcc cagttcaaga ggctgatatc cccatccaaa taaaaaatac
     6241 caatgatcct ttcgctcaag ggacaaaaat atcgaatcac gaaatagaaa aggaaaatgg
     6301 actgacagga atagctggac gcaaggattt tctttccatc actttattca aacgtcatat
     6361 gtccgatgaa atcgggttta tctggaaagc aatgagcatt tttgctaaac atgagatatc
     6421 aatcgaacat attccttcag ggatcgacaa tatcggagtg atcgtctcag cagaagcgat
     6481 tgccgataag ttatttctca tcacgaaaga attaaaagaa acacttggcg tggaagaaat
     6541 cgtcgtgatc gaagacttag ctttgatctc tgtcgttggg ggtccgcata aagaattgat
     6601 tggattatct gggaaagtgt tatcgatatt gaacaaatta gaaattcgca catcgatctt
     6661 atcacaagga gcacaggagt tgaatctgat catcggtgta ccgaataatc aatatgaaac
     6721 agtagtgaag ggtatctatg aagggatggt gaatacggat gctgaaagaa tatcgaatgg
     6781 cactccatca aattcctgaa atcgggtttc atgaattcaa gacaaaaaaa tatttatatg
     6841 aacaagtaaa aaacagcggg gccgttatcc atgaaatcgg cgaaacagga ctactccttt
     6901 attttgataa tcagcaagaa gaaacgattg cttttcgaac agatatcgat gcactgccag
     6961 tcaaagaaga aacgaatctc tcttttgctt ctaagcatga aggttatatg catgcatgtg
     7021 gtcatgacgg acatatggcg atgcttttag ggttgactga ctttataact aaacacattg
     7081 aggatcttat ttataatgta gtactgatct atcagccatc agaagaaatt tccggtggcg
     7141 cacaaagcgt tattcagtca ggattgttgg ataaatatga agtacaagca atatttggct
     7201 ttcatctatg gcctggacta gctaagggag aagttttctc tcgaccagga cctttgatgg
     7261 cacaaagcag tgaaacagac attatcatta aaggccagtc tgcacatatt gcttctagtg
     7321 aaaaaggaat cgatagtctg gaggcagctg tacgattttt gaagaatgtt tatgattttg
     7381 accggcaatt accggcagag tggaatcatc taatgaaatt tggccaaatc caaggtggaa
     7441 cgatccgcaa tgttttagct ggagaagtta ttgtatccgg aagtatccgt tcttacagtt
     7501 cagatatgca aaattatttg aagaggggat tagaccattt agcagaacag tttcactcta
     7561 cagctactat ttcttttcgc tataatgacg gctatccagc tgtaatcaac catagaggct
     7621 tatatgcagc actgttagat tcaaacaaac tacatgaatt agatgctcca gttcttcaag
     7681 ccgaagattt tggcatatat acgcaacaat atccatgtgt atttttcttt ttaggtgtcg
     7741 gtgatacccc tgctttacat gatccgacgt tcgattttga tatggatgtt ttagaaaatg
     7801 gtgtagaatg gtacaaaacg attcttttta cagaaaatct tcttgtaaaa atcgatagca
     7861 gttcaaaaga ggagcgagta aataatgatg aatttatcca atcgatttag tcctaggctt
     7921 tctagaatag aagtatcaaa aatacgacaa ttcgatcagc aaatatcgtc gataccagat
     7981 gtgatcaaac tcaccctggg agaaccggat tttccaactc ctgaacatgt caagcaagca
     8041 ggaatagcag cgattgaaga agacttttct cactataccg gaatgagagg attagaggaa
     8101 ctgcgggaag cggcttgtat atttcagcaa cagcgttatg gattaactta tgatccgcaa
     8161 acggaagttt tgacgacagt tggtgcaacg gaagcgattg cctctgcgtt gttatctgtt
     8221 ttggaagaag gagacaaggt tcttattcca gcgcctgctt attcaggata tcagccatta
     8281 gtggaactag ctggtgctga attgatcccg atagatactt ctgacacagg gtttgtctgt
     8341 cagccggaac aatttgaacg agcatttgaa caatatggat cagctgtcaa agcagtcatt
     8401 ttaaactatc ctaacaatcc tactgggacg acattgtctg caaaacaatt gaaagcaatc
     8461 gctgaggttt taaaaaaata tccggtattt gttataagtg atgaagtata tgctgaattg
     8521 acttatagtg gaacgcatat gtccatagct acttatcttc cagaacaaac aatcgtgata
     8581 agcgggttat ccaagtcaca tgcgatgact ggttggcgag tgggctttat ttttgctcaa
     8641 aaagccctta ttgacgaact aattaaagtc catcaatatc tggtgactgc cgctacaacg
     8701 atgtcgcaaa aagctgcggc tgaagcgcta ataaatgggg tgaaagatag cgagaatatg
     8761 aaagagcaat atcaaacacg aagagactat ctggtccagc aattggcgcc tttaggattt
     8821 gaagtgaccc agccaaacgg tgcattttac ttgttttgca aactcccagc tgccattcaa
     8881 actgactctt ggcagttttg tgtagaatta gcggaacagg caaaagttgc gtgtatccca
     8941 ggaattgcat ttggcccaga aggagaaggt tatatccgga tttcttatgc tagcagcatg
     9001 gaaaaattac atgaggcctg caaacggatc aaagactttt taacagaaca gtgattcata
     9061 gattttatca aaaaaacaat cgttaatttt gcggtatatt ctgcaaggag acgattgttt
     9121 tttaaattta gttcaaatga acgcgtttct tttgattcat aactaatgta atgttaagtt
     9181 taaattgttt agaatgattt taaaagaata ttcaaggagg tttcatcaat ggaaaaaatc
     9241 aaagttgtca ttgtaggtgc atctcatgga gggcatcaat cgatcttgga actattgaca
     9301 cgatacggtg aaaatgtaga tatcacgcta tttgaagcag gagactatat ttccttcatg
     9361 tcatgtggta tggagctgta tttagaagac aaggtaacag atgtaaatga tgtacgtaat
     9421 ttcagaccag aaaactttcc gcaatccaat gttcatattt taaataatca cgaagtaaaa
     9481 acgatcgatg ccgataaaaa aacagtaacg gttactagcg catcagataa cgaaacaaaa
     9541 gaatatcctt atgacaaatt gattttgagt tctggtgtca aaccaaacaa tctgccagta
     9601 ccaggagcag atctagaaaa tgtctacttg atgcgtggat acaattgggc aaccaaaatc
     9661 aaagaaaaat taaatgatcc ggctattaaa aaaatcgctg tcgtaggtgc gggttacatt
     9721 gggatcgaag cagcagaagc aagccgaaaa gctgggaaag aagtcgtatt gcttgatgtg
     9781 atcgatagac ctttaggcac ttatttagat gctgagatga cagatatttt agaacaacac
     9841 ctaaatgaaa acggtattga agttttgaca aatgcaaaaa tcgaagcttt tactggtaac
     9901 ggaaaagttg aggcaatcaa aacaagtgaa aaagaaatcc cagcagatct agtcattcaa
     9961 gctgccggtg tgaaggcaaa tacagaatgg ttaaaaggga tcgtcgactt agatgaacgt
    10021 ggctggatcc aaacaaatga atacttgcaa acgaatcttc cagatgtgta tgcagtagga
    10081 gatgctacac ttgcttattc tatcccagca cgcaaaaaaa tgccgatcgc tttagcgact
    10141 gttgcacgta gagaagcacg ttatgtagta aaacatcttt ttgaagaagt accaaacaaa
    10201 ccgttcggcg gagtcgtagg ttcctctgca ttaagtgtct ttgactatca ttttgcagca
    10261 agcggattga atagctttac agcagcaaaa gcaggagtag atgtacgagt gtcttattat
    10321 gaagatacgt tacgaccaaa atatgtacca gaagaacaag gaaatccaaa agtgtccatc
    10381 caattattct cggatccaat gacccatcaa ttgctaggag gagcagtatt atctacctat
    10441 gatgttacag gtcaaggaaa tgtattggca ctagcgatcc aaaacaaact gactttagaa
    10501 gaactagcag aagctgactt cttcttccag ccaggctttg accgacaatg gagcatgttg
    10561 aatctagccg ctcaacaagc gttaggagaa gaaccatttg tagaataaga aaacgaaata
    10621 tttgaaaaga ggttgtgaaa aagctgcctt gcatcaagta ataagaacag ccaagtaaaa
    10681 acagcttctt atgtttttaa cttggctgga cttattaccg cagatgcaag cttttgaaca
    10741 ccgtttattt tcaaaaaagg gactgtgaca cgatttgtgt accgaccccc aaaagttaga
    10801 ccaaaaaatc taacttttgg aggtcggtat tttttatggt taaatatact tttgaactta
    10861 aattaaagat cgttcatgat tatttggatg gcaaaggcga ttggaccgta aaaatccaga
    10921 tcaagagatt gaagcggaaa tgcttaaaat tcgggagaag cacaaggatt atggctgttt
    10981 acggatgacc aatgaactaa gaaaccgcgg tttctctatc aataaaaaga aagttcagcg
    11041 cttgatcaag aagctaggaa taaaagtaac ggcatacacg cgtaaatcac gtcgctacaa
    11101 ttcttatcga ggaaaagt
//
LOCUS       DARBDN010000084        10922 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000084 DARBDN010000000
VERSION     DARBDN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.085"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..281)
                     /locus_tag="SCH06_002196"
     CDS             complement(<1..281)
                     /locus_tag="SCH06_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078736.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEA"
     gene            423..1541
                     /locus_tag="SCH06_002197"
     CDS             423..1541
                     /locus_tag="SCH06_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEG1078737.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            1669..3045
                     /locus_tag="SCH06_002198"
     CDS             1669..3045
                     /locus_tag="SCH06_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEG1078738.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            3446..5026
                     /locus_tag="SCH06_002199"
     CDS             3446..5026
                     /locus_tag="SCH06_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEG1078739.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            5224..5447
                     /locus_tag="SCH06_002200"
                     /pseudo
     CDS             5224..5447
                     /locus_tag="SCH06_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
     gene            complement(5652..5972)
                     /locus_tag="SCH06_002201"
     CDS             complement(5652..5972)
                     /locus_tag="SCH06_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEG1078740.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(6120..8354)
                     /locus_tag="SCH06_002202"
     CDS             complement(6120..8354)
                     /locus_tag="SCH06_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1078741.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            8833..9099
                     /locus_tag="SCH06_002203"
     CDS             8833..9099
                     /locus_tag="SCH06_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEG1078742.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            9099..10826
                     /gene="ptsP"
                     /locus_tag="SCH06_002204"
     CDS             9099..10826
                     /gene="ptsP"
                     /locus_tag="SCH06_002204"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEG1078743.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
BASE COUNT         3479 a         1911 c         2215 g         3317 t
ORIGIN      
        1 gcttcttcaa tcaatatttt tcctaaccct tggtgtctgt attcagaaag aatcgccatc
       61 cgctgtaatt tcatttttcc gttttctaaa ggcaaaagac gtacagttcc ttgcggttct
      121 tttttatctg agtacaggac gaagtggata caatgggctt catctttgtc tatttctcga
      181 gacaaaggca caccctgttc gactacaaaa acttgatgcc tgatccgtac agcatctaag
      241 taaatattgc tcattgtatc ttttgtttgt acaactttca tggtctagcc accttccttt
      301 cgtatagtat actggaaaat aaaacaaata aaaagtatgg caagttttca aaaataaaaa
      361 aagaataaaa gaatttttaa cgaatataat atatactagt aagaaagaaa ggaggaaatc
      421 tattgtttga aaaacttaga cagtctaaac taatgttttg gtcgcttgaa ttattgatca
      481 tagctgcatt gatcatgatt tcatcagaaa taaactttat tttcgaaccg atcgggacat
      541 ttttttccac gttatttgca cctgtactga ttgcaggctt tctttactat ttattgaatc
      601 ctattgtcaa gctgttgatg aaagcaaaaa tcaaaagaat atgggctgtc gcaattgtgc
      661 tgctcctttt agttgcagca attatttgga ttttacttag tgtcatccca agtctagtac
      721 agcaaatttc ctcattggca tctaatatgc ctgatttcat caaacaggta gaaagctggt
      781 taaaagaggt agccgaattg cctttgttca aggaagtaga tatcaataaa tattttgagc
      841 aattagacat ttcttacggg acaatcattc agcaattcct tagtggagta tccaatagtt
      901 taggttcgat cgttggaacg atcgcttcgg caaccgtagt aatcattaca gcaccattca
      961 tcttgttcta tatgttgaaa gacggagaaa aactagtgcc aaacatccaa cagtttttcc
     1021 cagaaaaaag aagaaaccaa attgtggagt tattggggca actgaataaa acattggcta
     1081 attacattag cggacaagca atcgaatgtt tattcgttgg taccttcaca tttttaggat
     1141 atatggtaat tggtgtggat tatgctttct tatttggggt cattgcggga ttgacaaacc
     1201 taattccata tttaggacct tatctaggac tagcacctgc atttctagta acagtcttca
     1261 atgatccggt aaaagcatta ctttgttgtg tggttgtgct aatcgtccaa cagttggatg
     1321 ggaatatcat ttatcctaat gtaattggga aatcactgaa aatccatcca ttaacgatca
     1381 ttatcgttct tctagtagct ggaaatattg ccggattgct tggtatcttc ttaggtgttc
     1441 ctttttacgc aatctgcaag acgatcattt cctatataat caaaatcgtc aaagaagaca
     1501 agcaaaatga aaacaagaag aaaattgcta cgacctcgta ggtagtttta gtacacttgt
     1561 ttttattgca aagaaaattg ctttgtgata ccattttaac gtggctatag tgccacgttt
     1621 ttttctatcg taaactaaaa attaatttta taaggagaga atgcgattat gaatgctgac
     1681 cctgagagtc agtcgctgtt agcgcagatt ttattattga tcgttttgac attgatcaat
     1741 gcttttttag cagcttccga aattgctgtt gtttcgatca ataagaatcg aatcgagcaa
     1801 aaagctgatg aaggagatgt gaaatctcaa aagcttttaa aaatattgca gaatccaaat
     1861 aatttcctat cgacaatcca agtaggaatc actttggtca acattttgtc tggtgcttca
     1921 ctagctaata ctttatcgga acggttagct ccggtattag gtggcggcac agcggcaaaa
     1981 aatattgcaa atatcattgt gctggctatt ttgacctatg tatcgattgt ttttggagaa
     2041 ttgtacccta aacgtattgc tttaaataaa tcagaagaag tcgcaaagtt cacttcaggg
     2101 ctgatacgct tgattggtgt agtagctaag cccttcgtct ggctgctttc tgcttccaca
     2161 agtttattgg cgcgtatcac gccgatgact tttgatgatg aagattcaaa aatgaccaga
     2221 gatgaaatgc gttatatgct tgaaaacgaa ggcgtattga ataatgaaga attagaaatg
     2281 ctccaagggg ttttttctct tgatacgaaa gttgcccgag aagtcatggt cccacgaacg
     2341 gatgcattta tgattgatat caacgacact gtggaagaaa atgtgaatga agttttatcc
     2401 gaaaactatt caagaatccc tgtttataac gaagacaaag ataaagtagt cggaatcctt
     2461 catacaaaga atttactaaa agctgcccat aaattcggct ttgataattt agatatcaag
     2521 aaaatcatgc aggagccttt attcgttcct gaaacggtct ttattgatga tctgttatat
     2581 gaaatgaaaa agacgcagaa tcagatggct attttattag atgaatatgg cggcgtcgtt
     2641 gggttagcaa cactagaaga ccttttagaa gaaatcgtcg gagaaatcga tgatgaatca
     2701 gatgaagttg agaatcttta tgaaaaaatc gatgaacacg aatatatcat ccaaggacgt
     2761 atgctgattg atgagttcaa tgaagctttt gacagtgatc tgcatatgag tgatgtagat
     2821 acgatggctg gttatttgat tacagcatta ggcatgattc cggatgaagg cgaaaagtta
     2881 tcgtttgatg tcgataatat tacgctggtt tctgaagaaa tggaaggttc tcgaatcctt
     2941 aaaatccgtg tcatttttca tgatccggaa gaaacagaag cggaacctga agaagaacga
     3001 agatacttca gaaaagaatt cgaagatgac gagccaagaa gataattgga aacttggtta
     3061 tgaaagacgt gttgcttgaa taaacaagca acacgtcttt tcttttagtc agctgacaaa
     3121 aaaatatttg actcttatgg tttggtggct ttttcattcg ctgaatccat gctatactga
     3181 ttcagttgta gtagttgaca aaggttgtga aaaagctatc ctgcattaag taataagagc
     3241 agccaagcaa aaacagcttt tcgtattttt ggcttgggtg ggcttattgc tgataggctg
     3301 tctctagaac gccgtttact cggaaaaaga gactgctaca cggcttttgt cacagcccta
     3361 tatgaaattg tctttcttta agagatcgga caatctgtgc ctagagaaaa tataaataat
     3421 tgaatggaag aaatggagtt aggttatgaa taatccaaaa ttaaagcaac aagtggacaa
     3481 tcgcagaact tttgcgatca tttcccatcc ggatgctggg aaaacaacga ttacagaaca
     3541 attactattg tttggtgggg ctatccgtca agccgggacc gtaaaaggca aaaaaacagg
     3601 taattttgcc aaatcagact ggatggaaat cgagaaacaa cgtgggattt ctgttactag
     3661 ttctgttatg cagtttgatt atcaagggaa acgagtaaat atcttggata caccaggaca
     3721 tgaagatttt tctgaagata cttatcgtac tttgatggcc gtggatagtg cggtcatggt
     3781 aatcgatagt gcaaaaggga tcgaagcaca gacaaagaaa ttattccaag ttgtaaaaaa
     3841 acgtggcatc ccgatattta cttttatcaa caaactagat cgtgatggtc gtgaaccatt
     3901 ggaattgtta gaagaattag aagagctatt agatatcgaa tcttatccga tgaattggcc
     3961 aatcggtatg ggtaaagggc tagaaggtct ttatgatatc taccataatc gtgtagagtt
     4021 ttatcgtccg gaaaattatc aggatgaacg attagtagaa ttggatgaag atggactgct
     4081 tcccgaaaat catcctctaa ctgaaaattc cttatatgaa caagtcttag aagaagtaga
     4141 actaatcaaa gaggctggag atgcatttaa tcaagaaaaa attgctcgtg gcgatcagac
     4201 accagtattt tttggttctg cattgactaa cttcggtgta cagacttttt tagagacttt
     4261 cgttgaattg gcaccagctc cttatggaca caaaacacaa gatgatcaga tggtaagtcc
     4321 ttatgaggaa gaattttcag gtttcgtatt caagatccaa gcaaatatga atccagccca
     4381 tcgtgaccga atcgcttttg tccgaatctg ttctggaaca ttcgaacgag gaatggatgt
     4441 ctggttggaa cgtacaaata aaaaactgaa attaagcaat gtcacacaat ttatggcaga
     4501 ttcgagagaa aacgtcgaaa aagcagtagc aggcgatatc atcggtgtat atgatacagg
     4561 caattatcag attggggata cattgttcga aggaaaacta aaagttgctt atgaagaact
     4621 cccttcattt actccagagc tgtttatgaa agtgactgca aaaaatgtca tgaaacaaaa
     4681 atccttccac aaaggaatct atcaattagt tcaagaagga gcgattcagc tttataaaac
     4741 atatctaacg gaagaatata tcattggagc tgttggtcag ctacaattcg aagtattcca
     4801 atatcgtatg ttaaatgagt ataacgccga agtaatcatg tctccaatgg gacacaaaat
     4861 cgctcgctgg atcgatccag aagatttgga tgagaagatg agttcaagtc gcaatatctt
     4921 ggctcgtgac cgtttcgacc aaccgttgtt cttattcgag aaccaatttg cagaacgctg
     4981 gtttgcggat aaatatccca atgtaaaatt aaaaagtttg atgtaaagaa gtcttgacac
     5041 aagctgccct gcatcaagta ataagaatag ccaaacaaaa acagcctctc atattttgtt
     5101 tagagccgtg acggattttc cgtgacggct ctttttacta tattaaaatc atagaaatgt
     5161 ctaatcaaaa aaatataaaa attattttgc gtacatatga ttaaagaaag gagagtgtga
     5221 cacatggaaa cagaatggca aagacgtgaa agaaaaaaac agaaaaagaa gagatgttac
     5281 gattatgtcg attattagat gtaaaagact gggacaaaaa cgagcaaatt gcacaaaaag
     5341 tacgatcaat catccataaa gaggaaaaag ttaaaaataa agacacgcgt agaactgaaa
     5401 atgaaaagag aaaagtacaa aagaaaagag aaaaatcaaa aagctagaaa gaaaaagagg
     5461 ctgagacaga agcgtttaac tccaagaaat aagctggaat tcacaaaaat ttgaaaagca
     5521 attttcgtga atttcagctt atttccgaag gagttgcttc tgctttcgcc gtttatacgt
     5581 gtttagagcg tgagacaaaa gtgttcttta cttttgtccc acgctcttta attattatgt
     5641 tcaaaatttg tttacacggc taatgtagcg cctaattcat gttttggaat cgagatttca
     5701 acaaggcctg ccaattcgat tactttgatt tcatcctcgt ggtaaacggc gtctttgatt
     5761 ttatctaaga aataattttt agcatcttcg atttctttcg gctggatttt acgtttgtca
     5821 ttgatcagca gaatttcatt atgttcaggg gcttcagtgt agacaatagt ggtatttccg
     5881 gctgtgtaga ccttgactag atgggcatca gtgttttcaa gctggtttaa tacaagacgg
     5941 gaatggctgt ttgttacatt taccaatttc atggcgctca cctcttttat gtatttttaa
     6001 ttgcttgttt ctcttattat aatttctttt ttataaaatg aacagtattt tgacttttct
     6061 gaaaaaagaa tgagacggca tttctcaaag aaataccgtc tcacgctata aaactggatt
     6121 tattcagccg tttcttcggc tgattcttta gccaaacgtt ctggtttaga agtaacgatg
     6181 atttttccat ctttatccag ttttgctttc aactcatgga tagaagggtg atcaagataa
     6241 aattcagcga taccatcttc gatttgttct tggatcgtgc gtcgaagagg acgagcaccc
     6301 atagatggat catagcctaa gtcaactaat ttttctttga cattcgtagg aacttcgatg
     6361 tgaagttgct gtgctgccag catttggttg acatcgtcta gcattagtgt gacgattgtc
     6421 atcaagtttt cttttgataa tgcactgaat tcgatgatcc cgtcaaaacg gttcagaaat
     6481 tctggtgtaa agtagttgtt taattggttc aatacagaac gagtaacacc ttcgcgtgcc
     6541 gcaccaaaac caacgtttgc ttctacttta ccagttccgg cattacttgt cataatgatg
     6601 atcgtatctt taaagctgac cgttcttcct tgtgcatctg tcaatcgacc atcatctaag
     6661 atttgcaaga acatatgcaa aacatctgga tgagcttttt ctacttcatc taacaagaca
     6721 agactgtaag gatttctccg tactttttct gttaattgac cagcttcttc gtatccgaca
     6781 taacctggag gagaaccaat caatttagag acactatgtt tttccatata ttcagacata
     6841 tcgaaacgaa tcattgaatc ttgtgaaccg aatagttcgt aggcaagttg tttcgcaagc
     6901 tctgttttac ctacaccagt tggtccaaca aataagaagg agccgattgg acgattctgt
     6961 ttgtttaatc caacacggtt tcggcgaatc gctttcgcta ctcgatctac agcgttatct
     7021 tgtccgatga catgagcttt caagtcatct gctaagtttt tcagttgtgt ctgttctttt
     7081 tcttttaatt cacccactgg aatacctgtc cgttgttcaa cgattttttc catatctttt
     7141 tcggtaatca caggtgtttc ctcttcagtg agctgacgtt ctttcatttt ttgaagttta
     7201 ttgatctgat cgcgataata agctgctttt tcgaaatctt cttctcgaga agctaaaact
     7261 ttttgttctt ctgcttcttg cagttttttc tcgattgttt taggatcaac gatttggatc
     7321 gtcaagtttt tcttagaacc tgtttcatct agcaaatcga tggctttatc cggcaagaag
     7381 cgatcttgga cgtaacgatt ggataaagtt gcggctgctt cgatggcctc atcagtatat
     7441 tttacatgat gatagtcttc ataacgtttt tgcaaacctt tcaaaatact gatcgtttct
     7501 tcgacagttg gttcatctac ccgtacaggt tgcatacgac gttctaaagc agcgtctttt
     7561 tcgatgatgc ggtactcatt taaggtagta gcaccaacca tttgcaattc tcctcgagct
     7621 aaagctggtt ttaaaatatt accagcatcc atatttccat caccagcaga accagcaccg
     7681 acgatttcgt gaacttcatc tatgaatagg atcacatttt ctgcttgacg gatctcttca
     7741 atcaattttt gcatacgttc ttcaaattgt cctcgtatac cagtaccttg gactaaagat
     7801 acgacatcta aacgaatgac ttctttgtcc attaattttt gcggtacatc accatctacg
     7861 attttttgtg ctaaaccttc aacaactgct gttttaccaa cacctggttc tccaatcaag
     7921 acaggattgt tcttggttcg gcgatttaaa atttcaatga ctcgtttgat ttcgtcatcg
     7981 cgtccgatca caggatcgat atcaccttgt cgtgcttgtt ctgtgatatt gattccgtat
     8041 tctcccaata aaccttctgt attgccttga ggtggctgac caccattgaa gttgttgttt
     8101 ccgccaaatt gtgttggtgg tgtttgctca taatttcctt gctgttgcat ttggcgagac
     8161 atggaacgga aaagatcgtc caaactgcca aatccaaatg gatcattttg ggccatatta
     8221 gtcagacctc cattttgttg atttttgatt ttttgataac agctctgaca gtaatcgagt
     8281 tgtgtccgct gaccattgac agtggcatac aagtgaatcg ttgcctcatt cttgccgcag
     8341 ttttgacaaa gcatgaatca ttcacgtcct ttcacaaaaa tgggtacatc catattttac
     8401 atctcgtttt tcatgaggta aaagaataac ccctagtttt ttaagagatt tatgaggtag
     8461 aaaaggtgaa atctctattg accattcctg acctttgact cttattatac taaaaataaa
     8521 aagggaagca agtaattcgt ttcatatgaa aacaaagagg gtcaaaggaa agaatgataa
     8581 acgtcaggag aagagaaagc gacaagaaaa aggaaataaa cacgtttgtt ataaaatgtg
     8641 aagaaaagga tgaaaaagaa tccggaataa tttgaatact tttatctgaa attgaatgaa
     8701 aactgttgta tctaacgaaa aaaaatgtta atctttacag atgaaagggt ggcatttgtt
     8761 aggattctct gaattactaa aaaagaaaac cctcacataa aaacaacact cacttaaagg
     8821 agaccgatta atatggaaaa gaaagaattt cacgtagtag cagaaactgg gatccacgct
     8881 cgtccagcta cactattagt acaaacagca agcaaattta actctgatgt aaacttagag
     8941 tataaaggta aatcagtaaa cttgaaatca atcatgggcg ttatgtcttt aggtgtaggt
     9001 caaggttctg atgttactat tactgcagaa ggtgctgacg aagctgatgc aatggcagca
     9061 atcgttgaaa caatgaagaa agaaggctta tctgaataat ggttgaaatg ctaaaaggga
     9121 ttgccgctag tgacggtgta gccgttgcaa aagcttacct gctagttcaa ccggatttaa
     9181 cattcagtaa ggcaacagta gaagatactg cggctgaaga agctcgtttg gatgctgcat
     9241 tagctaaatc tactgaagaa ttgcagcaaa ttcgtgaaaa agcagcgcaa agcttaggtg
     9301 aagcagaagc gcaagtattt gatgcccatt tgatggttct ttcagatcca gaaatggtag
     9361 gtcaaatcaa gcaaaatatt aaagacaaca gcgtaaatgc tgaatcagcg ctaaaagaag
     9421 taacggatat gtatatcggt atgttcgaag caatggaaga taatgcttat atgcaagagc
     9481 gtgctgcaga tattcgtgac gttgctaaac gtattttagc gcacttatta ggcgttactt
     9541 taccaaatcc atcaatgatc aacgaagaag tggtcgttgt tgcacatgac ttgactccaa
     9601 gtgatacagc acaattagat cgcaattttg taaaagcgtt tgtaacagac attggtggac
     9661 gtacttcaca ttctgctatc atggcacgtt ctttagaaat tccagcaatc gttgggacaa
     9721 aagaaattac tgctaaagtc aaagaaggcg atattttggc tgtcaacggg atcgaaggcg
     9781 atgtaatcat cgatcctaca gatgaacaaa aagctgaatt tgaaaaagca ggtgcagatt
     9841 acgcagcaca aaaagcagaa tgggaaaaat taaaaaatgc agaaactgtc acagctgacg
     9901 gcaagcattt tgaattagct gcaaacatcg gaacaccaaa agatctagtt ggtgtccata
     9961 ataatggtgg agaagcagtt ggtctgtacc gtactgaatt cctgtatatg gattctccag
    10021 acttcccaac agaagatgac caatatgaag cttacaaagc tgtattagaa ggtatggaag
    10081 gaaaacctgt agttgttcgt acaatggaca tcggtggaga taaagaacta ccatatctgc
    10141 aattacctca tgaaatgaat ccattcttag gatatcgtgc attgcgtatc agtttatctg
    10201 aacaaggcga cgaaatgttc cgtacacaaa tgcgtgcatt gcttcgtgca tctgttcatg
    10261 gtaatttacg tatcatgttc cctatggtag ctacactcaa agaattccgc gcagcaaaag
    10321 cgatctttga agaagaaaaa caaaaattga taagtgaagg caaggaagta tctgatacga
    10381 tccaagtcgg catcatgatc gagattccag cagcagcagt cttagcagac aagtttgcaa
    10441 aagaagtaga tttcttctct gtaggtacga acgatttgat tcaatacaca atggcagcag
    10501 accgtatgaa cgaacgcgtt tcttacttgt accaaccata taacccatca attttacgtt
    10561 tgatcaaaaa tgtaattgat gcagcacacg ctgaaggaaa atgggcaggt atgtgtggag
    10621 aaatggctgg agatcaaaca gctgttccat tgctagtagg tatgggtcta gatgagttct
    10681 caatgagtgc gacatctatt cttaaaacgc gtagtttaat gaaacgcttg gacacagcga
    10741 aaatggctga acttgctgat cgtgcattga aagaatgcga tatgatggaa gaagtcgttg
    10801 aacttgttca tgaatatgta aaataaacaa cgtatcaaaa gctggtgtgg cttgtaaaag
    10861 agctacgcca gtttttttgt tcttttttaa gaaaacgttt ttgtcagtaa gaatagacaa
    10921 aa
//
LOCUS       DARBDN010000085        10834 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000085 DARBDN010000000
VERSION     DARBDN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.086"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            34..657
                     /locus_tag="SCH06_002205"
     CDS             34..657
                     /locus_tag="SCH06_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078744.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1107..2156
                     /locus_tag="SCH06_002206"
     CDS             1107..2156
                     /locus_tag="SCH06_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1078745.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2153..3034
                     /locus_tag="SCH06_002207"
     CDS             2153..3034
                     /locus_tag="SCH06_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078746.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3037..3807
                     /locus_tag="SCH06_002208"
     CDS             3037..3807
                     /locus_tag="SCH06_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1078747.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4086..4940
                     /gene="aroE"
                     /locus_tag="SCH06_002209"
     CDS             4086..4940
                     /gene="aroE"
                     /locus_tag="SCH06_002209"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEG1078748.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5118..6281
                     /locus_tag="SCH06_002210"
     CDS             5118..6281
                     /locus_tag="SCH06_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEG1078749.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6398..6808
                     /locus_tag="SCH06_002211"
     CDS             6398..6808
                     /locus_tag="SCH06_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEG1078750.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6982..9210
                     /gene="topB"
                     /locus_tag="SCH06_002212"
     CDS             6982..9210
                     /gene="topB"
                     /locus_tag="SCH06_002212"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEG1078751.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9381..9665
                     /locus_tag="SCH06_002213"
     CDS             9381..9665
                     /locus_tag="SCH06_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078752.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9825..10061
                     /locus_tag="SCH06_002214"
     CDS             9825..10061
                     /locus_tag="SCH06_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEG1078753.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10058..10456
                     /locus_tag="SCH06_002215"
     CDS             10058..10456
                     /locus_tag="SCH06_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEG1078754.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3788 a         1796 c         2270 g         2980 t
ORIGIN      
        1 taataaaaaa taggagaaaa agtagaaaag aaggtgtttg ttatttggga agtagttaaa
       61 tcgagagtac aagaaatgaa tgaacatttc tcagtgtcat tcgcagaaaa tccaagtaag
      121 tattttcgac gtcttgtttt tctgctcatc ttatcattgc tgttaacagt tgcaatgttt
      181 ttattgccgg aaaaaatccg agaagagcaa gtaaatagtc tcgtttattc gtccatacca
      241 accagcaaat tgaaaccttt tgattacagc aaagctgatc agaaaatcaa acaaagccgg
      301 gcgatatcgg tgatgttcag caaaccgaac gggaaaacct atcaggacat gcttgatgtt
      361 tttaatgatc ctgagcttat ggaagaattg aatcgaccga tcttttatta tccgatcgtt
      421 tatgatgtac atgaactgga acaaaaatat aacatacgaa cggatgaagt gacatttatt
      481 ttctttgatg gaggaaaaga agcaaatcgg ataactgcgg gtaagggagg aataactgat
      541 tttgataagg agttgatccc tgaactgaat cgacttccgt tagccaatat caaacaatta
      601 gaagaagaat tggatagaac gggagtaact tcccaaaatt ccgagattgc taattgagac
      661 attggcgcga tgaaacggtg ggtctatata gcgctatttt taattatcag aacaagtgat
      721 gtttgatctt caaaataaca aataaaaaat taaaaaatat agttgacgaa attcaaaaat
      781 tcgattagac ttaaatcaat tcttaaggaa agggtgacct gtaatgaact tatcaaaacg
      841 tatttcagca gaaaacaaaa aaaattggcg cagctggcgt agataagttg tattaatggt
      901 gagactttcc catagataca actttttaga gtgcatttct aaagcttgta tctatgctag
      961 acatgaacat tgactgccgc atagattaga atctatgcgg ttttttgtgt aaagacaatg
     1021 accgctttgg ccattgtctt tttttgtaga ctggatactt gcctgattat aataaataaa
     1081 aagattgact ttgcaggagg aaaaaaatga aaaacaaacg attaataaca gttgtagtaa
     1141 ttattttagt ttatttagca ggtgcattta tttatggaaa agcctcaggc gaaaaagaaa
     1201 gtacttcgac gaaccagaca aaaaaaacaa cagttgttgg ggtattgcaa tacgtgagcc
     1261 atccggcatt agatgagatt tatcgaggaa tcaaagatgg tctgaaagaa gaaggattaa
     1321 aagaaggaga aaatcttgag atcaaatttc aaaatggaca agccgatcag agcaagctag
     1381 ccacaatgag tcaacagcta gtacaatctg atccagatgc cttgattgga atcgcaacac
     1441 ctgccgctca atcattagca aacacgactt catcgatccc agttgtgtta ggtgctgtaa
     1501 cggatcctgt gggggctgga ttagtcgctt ctttagagaa acctggtggt aatgtaacag
     1561 gtgtttctga tcagccgcct gttacttcac aaatcaagct tgcttctgat ttgttgccaa
     1621 atgcaaaaaa agtcggaatc ttgtatgctt cttcagagga taattcaaaa taccaagtag
     1681 cacaagcaga agaagctgca aaaaaagaag ggttagaatc agtaaaatat gcggtgcctt
     1741 ccactaatga gattgcacaa acggttcaag tgatgagccg acaagtcgat tttatctatg
     1801 ttccattaga taataccatt gccaatgcga tgcaaacagt ggtaaaagaa gcaaacaaag
     1861 caaatatccc cgtcattcca tctgtggata caatggtgga acaaggtgga ctagcaacaa
     1921 tcgggatcaa tcaatatcaa ttagggcttc aaagcggtaa gatggcggca gaacttgcga
     1981 gtggaaaaga aaaaccggaa acgacgcctg tttatacatt tgatcaaggg gatacagtga
     2041 tcaatcaatc tcaagctgat cgcttaggaa tcattgttcc ccaatcgatg aaggaaaaag
     2101 ccaaaatcat tacagatgac tcgcagcaag aaacatctaa ggaggatgac aaatgatcgt
     2161 atcagctatt tcacaaggca tgctttgggc aatattagga ttagggattt tcatgactta
     2221 tcggatctta gactttcctg atatgacgac agaagggtcc ttcccattag gtgctgctgt
     2281 ctgtgtgaca gctattactc atggggtagc gccgattgta gctacattat taggcgtagg
     2341 tgctggcatg atagcaggac tcgttacggg gttactttat acaaaaggaa agataccggt
     2401 tattttagca gggattttag tgatgtcagg attgaactca gttattttgt ttgtgatgcg
     2461 aacaccaaat ctttctttat tgaatcatcc gattctacaa gacagcttcc atcgctttgg
     2521 gttacctgat tactttgaca cagtccttct tggcttcatc tctttgggca tcttgattgc
     2581 tgtactgcta ttcttcttca atacagattt gggtcaaggc tatattgcga caggagacaa
     2641 cgaaacgatg gctcggtcgt tagggataaa aaccgatcgt atgaaaattt taggtttaac
     2701 tttgtcgaac ggtgtcattg cattatccgg tgcgctgatt gcccagaacg acggatatgc
     2761 agatgtaaat aaagggattg gcgtaatcgt catcggtctt gcttccatca tcatcggtga
     2821 agtgatcttc caagaattga cgctagcaga aagattgatt gctattgttg tcggcagtat
     2881 catttatcag ctattgattt tagtagtaat caaactaggg tttgacacga cttatctgaa
     2941 gttgttctcc gctatcatct tagctatttg tctgatgatc ccgcaattga agaaagcact
     3001 gaacttaaaa acgggttttg agaaggaggc atagtaatga ctgatatatt gacaatcaaa
     3061 aatggcagaa aagtcgtaaa caatggaatg aatgaagaga aagtactatt ggatgaaatt
     3121 aaccttacaa tcagagaagg ggacttcatc actgtccttg gcgggaatgg tgctggaaaa
     3181 agcacactgt tcaatacgat cgctggtacg cttcaactca gtcaaggatc gatctctttt
     3241 aaagatcagc tgatcacaaa agattcagaa gaaaaaagag cacgattcct ttctcgagtt
     3301 ttccaagacc ccaagatggg aacggctcct cggatgacag tagcagaaaa tttgctactt
     3361 gcacaaaaaa gaggtcaaaa acggaaattc cgtttacgta acttgaaaaa tcaaaaagaa
     3421 gattttttca gactatgtca agaagtcggt aatggcctag agcaacactt ggatactcca
     3481 gcgggtgaat tatctggtgg tcaacgccaa gcattaagct tgctgatggc gacgatcaca
     3541 gctcctgagt tactattatt agatgaacat actgcagctt tagatcctaa aacagctaaa
     3601 gcattaatgc gattaacaaa tcagcggatc aatgaacaaa aattgacttg tctcatgatc
     3661 acgcatcgaa tggaagacgc cttgaaatac ggaaatcgtc tgatcgtact ccaaaaaggg
     3721 aaaatcgttc aagatatttc tgaaaaagaa aagcaacatt tgacaatggg cgaccttttg
     3781 cagttctttg aagaagtagt ggattgattt cgacagaaaa attcctttca gtagaaggac
     3841 ttgaaaactc attgacatct tcctttgatt catcctatac ttaaaacaat aaacaattaa
     3901 acatatttgg gtgttttgta ggatcacgta gtcaatgatt ttaacaatta aatagaatat
     3961 tctttgctct gacaagtaaa cgatgagaaa agaatttgct actttgccac ctagacgttt
     4021 cgtacttttt cgtatcaaac gctaagtggc tttttttatt gaagtaagaa caaaggagga
     4081 ataagatgat ttctggacaa accaaattag ctgggctctt tgctgatccg gcttctcaca
     4141 gtttatcccc attgatgcac aatactgctt ttgaagcaaa caacatcgat gcggtgtatt
     4201 tagctttcca agtaaatcca atgaatttga agcaagcagt cgaaagtatt cgaacttttg
     4261 atatgttagg tgtaaatctt tcgatgccga ataaaacagc ggttattcct tatctggatg
     4321 aggtaagcca ggaagcgcaa ttgatcggag cagtgaatac gatcgtgcac gaaaagggtc
     4381 gtttgattgg ctataatacc gatggtgcgg gcttcatgca atccgtgcaa gaagctggga
     4441 tttcgatcaa aaagaaaaaa atgactctac tgggagctgg aggtgcagca aaggcagtca
     4501 ctgttcaagc tgcgttagac ggcgctgagg aaatcgtagt ttataaacga aacaaccaaa
     4561 cattcgctca agtaaaagaa acattcgaac aactcagcta tcgaacttct tgtaagataa
     4621 aagttcgtga ctttgccgat acgcatcaat taagaaaaga cttgaaagaa agctgtcttc
     4681 tagtcaatgc aacagatatc gggatgggaa agaaaatcaa tcagtcaccg ctcttagata
     4741 taagcatgat gcatgagaat ctagcggttt ttgatttgat ttatgcacct agagaaacac
     4801 gtttattaaa agaagcaaaa aaagtaggag caaaaggata caatggactt ggcatgttga
     4861 tctaccaagg agcaatcgcg tttgaattat ggacaaagga aaagatgccg atccatgtga
     4921 ttgaaaagct gtttgattaa aaaaggataa tagataaaga tcttttattc tcgcataaac
     4981 ggtctcaaga aaagtaatcc tttatgtatc gaagcattta tttcgttatt ttttattaaa
     5041 ttatcaaaaa atgataggct tttgtcgatt ggttatcgta tcctttattt atcagtaaga
     5101 aacgaggagg aaccacaatg agtcggatgg atcgctataa ggacatccat aagaaggcga
     5161 aacctctgaa gcgggatacg gggagtattt ttgctagaag agaacgaaaa cgaacgcgta
     5221 tggaaaatga ggaagatgct acccgtattt atgaaagaga gcagcattca tttgaacatt
     5281 tgaaccaata cgagcaacag atatacagag atgcaccaag agcagaagaa caacaaaaaa
     5341 ataaaaaatt tttcaatcgg caaaagaaga acaaaccgtt aaaacctcga agaaagcgat
     5401 cgtggaaaaa aatcattcta tcgattttgc ttgttttgat cctttattca ggtatctcat
     5461 tttttattgg taaatatgta gctgaacatg acacaagctt agaggcagcg acttcagaaa
     5521 cctttcatgg gcaaaaagcg acgaatggtg cgcataatat tttgatcctt ggaagtgata
     5581 cacgcggaga agatgccggg cgagccgata cgatcatggt cttacagttg gatggtcctt
     5641 cccataagcc gaaactgatt tcttttatgc gtgacagctt cgttacgatc ccaggggtag
     5701 gacaaaataa gatcaattca gcttatgcat acggaggagc cgatctagtg cgtcaaactt
     5761 tagtagaaaa ttttggaatc gattgtcaat actatgcgaa agtcgatttc aaatcgtttg
     5821 aaaaagtgat cgatgcctta ttcatgaacg gagtgaagat cgatgcagaa aaagatctga
     5881 atctggatgg tgtagatatt aaaaaagggg tccagaagat ggatggacat gttcttttgc
     5941 agtacgcacg tttccgaatg gatgaacaag gagactttgg ccgtgtcaga cgccaacagc
     6001 aagtaatgaa cgctattttc agccaattga agaatccatt gaatctgatc cgtgcacctt
     6061 atgcagctgg taaagcttta ggatatacat ccacagatgt cactgcttgg ttcttgacga
     6121 aaaacctctt ttcgattgca cgaggagctg gtggcattga tcgaataagt gtgccagtag
     6181 acggttcgtg gaattatggg caaagtgatt atgctggcag tattcttgaa attgataatc
     6241 aaatgaatca atctgctatt acagattttt tgaataaatg atcataaaaa agatcaagaa
     6301 gaagctgcgc aaggcttttg tcatgaatca atcaaacgat tcactcgtaa aaaacgcttt
     6361 cttatggtag atttaaccaa gagaggagct gtttacattg gatatctatc tgaacttcaa
     6421 aaatgagtcg cgtgaagcca tcgcttttta tgaaaaagtt tttcagactg aagcatcagg
     6481 tatcaccaca tacggtgaaa tgcctggaat agaacaaatg aacttgccag aagaagcaaa
     6541 aaatctaatc acgaatgcac ggctgaacat ttatgataca ttagttatgt ttgcagatac
     6601 gccagaagga attggtcctg aattagttgt gggaaataat gtttctttag tcatccagac
     6661 aagaaatgaa gaagaaacga agcgcctatt tgaaagctta gctgagggtg gtaagattga
     6721 gatgccactg gatgctgttc cgtgggctca gttgtatggg atggtaactg atcgatttgg
     6781 catcaactgg cagattaacc aagagtgaca gctaaagatg aatattttct ggaaacatca
     6841 agcagcaaac ggatcatcgt ttgtttgctt gatgtttttg tgtctatttc gactatacgg
     6901 tatctttttt ttattgccag atgcgaaaat atgttccata atagagaagt ccgcaaaaaa
     6961 ttaagtaacg gaggtcagaa gatgaagacg gtgatactag ctgaaaaacc ttcacaagca
     7021 aaagcctatg ccgaaacctt ccaacagcaa aagcggcatg aagggtatta tgaaatcagc
     7081 gatccattgt ttgctggtga agtaaccatc acttatggtt ttggacattt ggtagatatg
     7141 gttgctccag gagcttatga agagcgttgg gcaaaatggt ctttagaaaa tttgcctatt
     7201 ttcccagaaa ccttccgtta cgaagttcca atggacaaac gtgcacaatt ttcgatcgta
     7261 aaacgagaat tgcagtcagc cgataccatc attattgcaa cagatggtga tcgagaaggt
     7321 gaagccatcg cgtggtcgat tattcgacaa gcaaacgcat tttctaagga aaagaactat
     7381 ttacgtttat ggatcaattc tcttgaaaaa gaagcaatct atgaaggttt taagaatctc
     7441 caacctggaa agaactattt tccaaaatat aaagaagcgc aagcaaggca gaacgctgat
     7501 tggctgattg gaatgaatgg aagtccatta tatagcttgc tacttcaacg aaaagggatt
     7561 gatggcagtt tttctcttgg tcgtgtacaa acaccgacac tctatatgat ttatcagctg
     7621 caagaagaaa tcaaacactt caaaaaagaa acgtactttg aaggagaagg tttaattacg
     7681 acaaacaaag ggcagttttc tggaaaaatc gtaccaaaaa aagcatttaa aacccaagaa
     7741 gagttaacga aggaaataga aaaacttgga gcgcatttag gtaagcaaaa cggacggatt
     7801 cttgaagtta cgaaaaagga aaagaggttg catagtccac gtttattttc gctatctagt
     7861 ttgcagacaa agatgaatca gctaatgaaa gcaagtgcca aagctacact tgatgctgct
     7921 caaggattgt acgaaagcaa gtttctaagc tatccaagaa cggattcctt ttacattaca
     7981 gaaaatgagc atcagtatct ggttaaacat ctgcaaaatt ataaaaaatt tttaggaata
     8041 gaagaagtac agacaactga gatcaaagca aagaaacgat atgtcgatgc gaaaaaagtt
     8101 caagaacatc atgcaattat tccgacaaag acgattccga ctcctgcacg ctttgcgaag
     8161 ctttccaaat tacagcaagc aatctatttg caagttttgc gcactactgt ggctatgttt
     8221 gctgcagatt atatctacga agagacgacc gtaatgacgg gcgtacagca attaaagcta
     8281 aaaagcatcg gaaagatccc attacagcaa ggttggcagg aaatcttacg catcaagtca
     8341 aaaaagaaag aagctcagac tcttcctcct atcgtagaaa atgaagaagc agaagtagaa
     8401 ctgaaaagta tggagaaaga aacacaacct ccaaaaccct ataccgaagg aacgttgatc
     8461 acagcaatga aaactgcggg aaaaacgctg gataatgatg aagcgcaaga aattctcaaa
     8521 gaagtagaag gaatagggac agaagctaca cgagccaata tcattgaaaa tcttaagcag
     8581 aagcattaca tcgaagtcaa taaaaacgaa ataactgtta cgccaaaagg aatcactctt
     8641 tgtaaggcag tagccaatga accattactg acgagcgcag aaatgactgc gcgctgggaa
     8701 gggtacttga gaaaaattgg taaacaagag gggacaccat ctgttttttt agagaatatc
     8761 aaaaaattca tcctacattt attggcagaa gttcctaatc aaatcgacaa ggtagacttt
     8821 tcagatgaga ttagcgggac acgtcagata aaagcgatgg agaagaaaaa cgatcaatta
     8881 ggaagatgtc caaaatgtaa aaagggaata gtcatgcttt atcctaaaat cgctacatgc
     8941 ttgaatccgg aatgcgactt caaattgtgg ccaacagtag ctaaaaagaa gctgactaaa
     9001 acgaatctca gagatttgct ttcaaaagga aagacaagta aagttgtcaa aggttttact
     9061 ggtaaaaaag ggaaattcga tgcagtttta gtattaaaag aagatatgac aatcggtttt
     9121 tcttttccat ggatcgaaaa cagtggaaca aaagcagttg atggaaacaa agaaacatca
     9181 agaaaaaata atgaaaacga agtagagtaa atgaaaacaa tgaaatagcg gaatatttat
     9241 tccgaaaagt gagaatataa ataccaataa aactaaaaaa tatcagtgaa tcaagcaaaa
     9301 acgttggggt aggctgattt tatatagata gcaaggagtt tttttatttg aaaaaagtgc
     9361 attcattttt aaattatctt atgggagcaa tcacgattgt ggctgtgtac caagcatttc
     9421 taaagtatcc tgattacggg acgaagttgt tgtcattgac gcacaatcaa acagcatatt
     9481 caccaacgtt gattttatcg actttgactg caggagctaa aagcgctact tatttttttc
     9541 ataaaacgac aagcatgcta aagcgaaaga aacagcgaaa acaattgttg gtggtggtag
     9601 cggctatgat cattatttat tttctaccag ttattacaca agtatttcat caatattttg
     9661 gttaagaata cgagagtttg tgacaaaagt catgtcacaa acttttttct ttgtcatttt
     9721 ttcgtaagaa aaagcaaaat aaaagtatat acattgatta aaagtatata cttggatata
     9781 atgtacttac tatagaatga gaatggtata gagggtggcg aaatatgaaa aaaatgaaaa
     9841 agtataaaat tagaaaatct ggcaatagcg atgtaacaac tatcccacca gaagtaaaag
     9901 aattcatggg tgtgcagaca ggtgacgcaa tcagttatgt ttttcaatct gatggttctg
     9961 tacgaatgat caaagcacaa gaagaacctg atattgattc attagttgat tcgatcatga
    10021 atcaatatga agacgcgtta aaagatttgg ttgatttatg aggtatcttt cgactaaaga
    10081 aattatcaaa atcaacgcga aagttatttt acgtcactcg ccaggcgaaa tgatcggtgt
    10141 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
    10201 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
    10261 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
    10321 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
    10381 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
    10441 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
    10501 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
    10561 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
    10621 gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta cataatgtac
    10681 attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat
    10741 cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct
    10801 tacttttttt gtcgtttaat tgaatgataa aaac
//
LOCUS       DARBDN010000086        10723 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000086 DARBDN010000000
VERSION     DARBDN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.087"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(241..1089)
                     /locus_tag="SCH06_002216"
     CDS             complement(241..1089)
                     /locus_tag="SCH06_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1078755.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1088..2155
                     /gene="gnd"
                     /locus_tag="SCH06_002217"
     CDS             1088..2155
                     /gene="gnd"
                     /locus_tag="SCH06_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HEG1078756.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            2157..3158
                     /locus_tag="SCH06_002218"
     CDS             2157..3158
                     /locus_tag="SCH06_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HEG1078757.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3155..3439
                     /locus_tag="SCH06_002219"
     CDS             3155..3439
                     /locus_tag="SCH06_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HEG1078758.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3472..4269
                     /locus_tag="SCH06_002220"
     CDS             3472..4269
                     /locus_tag="SCH06_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEG1078759.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4283..5116
                     /locus_tag="SCH06_002221"
     CDS             4283..5116
                     /locus_tag="SCH06_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078760.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGGFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5134..5991
                     /locus_tag="SCH06_002222"
     CDS             5134..5991
                     /locus_tag="SCH06_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1078761.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6013..6522
                     /locus_tag="SCH06_002223"
     CDS             6013..6522
                     /locus_tag="SCH06_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078762.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6559..6960
                     /locus_tag="SCH06_002224"
     CDS             6559..6960
                     /locus_tag="SCH06_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078763.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7072..7425
                     /locus_tag="SCH06_002225"
     CDS             7072..7425
                     /locus_tag="SCH06_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078764.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7459..7902
                     /locus_tag="SCH06_002226"
     CDS             7459..7902
                     /locus_tag="SCH06_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEG1078765.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7919..9004
                     /gene="uxuA"
                     /locus_tag="SCH06_002227"
     CDS             7919..9004
                     /gene="uxuA"
                     /locus_tag="SCH06_002227"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEG1078766.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8997..9710
                     /locus_tag="SCH06_002228"
     CDS             8997..9710
                     /locus_tag="SCH06_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1078767.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9917..10066)
                     /locus_tag="SCH06_002229"
     CDS             complement(9917..10066)
                     /locus_tag="SCH06_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078768.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10462..10662
                     /locus_tag="SCH06_002230"
     CDS             10462..10662
                     /locus_tag="SCH06_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEG1078769.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3588 a         1694 c         2320 g         3121 t
ORIGIN      
        1 aaaaataata aaaaaaagaa aagataaatt ttttactact gtatactaac tttgttatcg
       61 catctaacaa gtaactcgaa taataccaat acaaccttct ccaaagatgc gatgacatac
      121 gttctaaccc accgactatt gatgttctgt accacccttg cagaaccaaa aaagccacta
      181 ccaaatattt ggtagtggct ttttttgttt tatggatttt tcgctttttc tgttatggtg
      241 ctattctttg atttcagaaa tagtatgtcg aactttagcg atagaacgac gtgattcttt
      301 ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa atgcttagtt gagaaatacg
      361 ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa atagaaataa aaacgacatc
      421 gccaagttta gcaagggaag aattagcttg gctagtaata acgattgttt ttgctccagt
      481 ttttcttacg gtttcagcaa tatggattgt ttcttttgat tgccctgtgt gagaaatcaa
      541 aacagcacag tctttttccg tcaataaaga agcttccatc aattgaatat ggtaatccgt
      601 gctgtgagaa gttgcgatag gggaacgcaa aaatttatga taagcgtcag ttgctacaat
      661 ctctgaaccg ccaacaccga aaaaatagac acgtttagat tcattgataa tagtagccgc
      721 tttttttaga tccttttgtt gtaacaactt ttttgtgtca tttaaagttg aaatactaga
      781 ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt ttctgaatat tttcgtggat
      841 agaaatagca gatagatcat tttcttggat caacatggcc attttaaaat ctttaaatcc
      901 attataacca agtttttttg taaattgaaa aaaagtagag tcagcaatgc ccagttcact
      961 tgctaaattg ctaataggac tatgacttac tttgcttgga ttttctaaaa tataatcggc
     1021 gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta gtcttatgga
     1081 gacgctcatg agaattcctc attttcataa taagattatc attttttccg ttctcattaa
     1141 tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa aatatttttg taaaatctat
     1201 ttacaaaaaa atttttttgt ataatgaggg tataagaaat ggaggcgcta tcatggaaat
     1261 tggtgtaatt ggtttgggaa aaatgggatt gaatttagct ttaaacttaa aagagcacca
     1321 tcacaaagta caaggactcg acatttcaag tacagctgtt agtcaggcaa gagaaaatga
     1381 cattcctgct tatcaagaga tctctgaatt tctagctact tttgagcaga aaaaaatcat
     1441 ctggttaatg cttcctgctg gagagataac cgaaaacatg ttaagaaaac tttttccaaa
     1501 actcggacca ggagacatta ttattgaagg cggaaactct tattataaag attcaatccg
     1561 tcgagcagaa gagtttcaga aaaatgaaat cggttacttg gattgtggga cttctggagg
     1621 aatcgaagga gcacgacatc aagcctgctt aatgattgga ggagataaag aaacttttct
     1681 atccgtggaa caattattca aagatgtagc aattgaaaga ggatatctgt atgctggtgc
     1741 atccggaagc ggacacttct tgaaaatgat ccataatgga atcgaatatg gaatgatgca
     1801 agcaatcggt gaaggattcc aacttgtaca aaaaagtgag tatgcttttg acttggaaca
     1861 agtcgcacgt gtttggaatc atggttcggt gattcgcggc tggctgatgg aaatcatgga
     1921 agatcagtta aacgaacatc ccaatttaag taattatcgg ggaatcgttt ctgcatcagg
     1981 tgaagcaaaa tggacggttg aaacagcgct agaaatggct gttccagttc cagtaattgc
     2041 aactagtttg ttcatgagga atctttcaca ggaagaagat agtttttcag caaaagtagt
     2101 ttcagcacta agaaatgggt ttggcggaca tgaaatagtt gaaaagggtg agtaaaatgc
     2161 cagattatca tatagcaatc gttaattcca gcagtttcgg aagagtcttt ccacaccact
     2221 tggaaagatt aaagtcagtt ggagacgttc atttctttac tgttgatcaa gagattccag
     2281 gaaaagaact agcggagtta cttaaaggat tcaatatcat tattgcaagt gttacgccat
     2341 tttttcgacg agattttttt gaaaacaaag atgaactgct attgatttcc cgacatggta
     2401 ttggttacaa caatattgat ttaaaagcag caaaagaaca ccagacaatc gtatctatca
     2461 tacctgcttt agttgaacga aatgctgtag cagaaaataa tataactaat ttgttgtcca
     2521 tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga cgatcgatgg gaagatcggg
     2581 cggagttcgt cggtaggacg ctgtttaaca aaacagttgg tgtgattggt gcaggaaata
     2641 ccggaagcgg agtaatcgaa attttgcgta acggttttcg ctgtgatgtt ctagcttatg
     2701 atccttacaa atcagattta tacatcgaaa gctttggtgc aaaaaaagta gaacttcaag
     2761 aattactgga acaatcagat atcatttgtt tatgtgcgaa tttgacagaa gagaactatc
     2821 acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa tgtttatcta tctaatagtg
     2881 caagaggcgc tctagttgat gaagaagcga tgattaatgg tctgaaaagc ggaaagatcg
     2941 caggatatgc cacagatgtt ttagaagaag aaccgggacg tcaagatcat ccgtatttag
     3001 cgtttgaaca agtagtgatt acgccacata tatcggccta cacaagggaa tgtttagaag
     3061 caatgggtga aaaatgtgtc agagatgtcg aacagatcag tcagcacctt cttcctgaac
     3121 gttctgtcca gacaaagagc aactatataa aaggatgatg aagaaaatgg tgaacggttt
     3181 aaaagtgaaa acaggccctc aattttattt atatgaagaa ggtggtattt caaaagtttc
     3241 tgatctcttg aaatcatacg gcgcgaaaag agtactggtc acccacggaa cggtatcatg
     3301 ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa acgattcaat ttttttatca
     3361 tcgttattct ggagaatgta gttatgctga agccagacga atagctacaa tcatcaaaaa
     3421 aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac tgaccgatct agtgggttat
     3481 agtgccaatc ttgcaagaat cgatttcgga gtcatcccta ctttagctag taattgtgct
     3541 ccatggacac ctcttgctgt catgtataag gagaatggac aagcagaagg gaaaacagaa
     3601 cacttttaca gacaagctgc tttttttata acagatcccc aattagtgat tgattcccct
     3661 gttccatatt tcattgccgg gttagcagat acactagcaa aatggtatga atctgagctc
     3721 atcttagaac aagatttttt gcaagatgaa tcatttttga agctagcaca agatactgcg
     3781 aagatctgca aagaagagat tttgaatcat tctgctaaag caatccaaga tatggcacaa
     3841 agaaaactga catcggagtt caaacagctt tcagagatta tctttgctgt tgctggttta
     3901 gttggaggat taggagataa atacgcaaga aatgcggcag cacatgctat gcatgacgct
     3961 atcagtaaat atattccgga aagccatcgt tttctacatg gagaaaaagt agcgtatggg
     4021 attttctatc aactggcact agaaggtcgc tgggaaaaaa tagacgagtt atatcctttg
     4081 tatcgggaat tagaactgcc ggtttctcta gaacaaatgg gattatttcc gaaagataaa
     4141 cagataatag ataaaatggc tgaatttatt gattcgaaag agaaagtgca tttgattcct
     4201 atagaggtaa cacagaaatc actgatacag tcaatgatgg aactggaagg ttatatcaga
     4261 aagatctgaa ggaggaggac acatggaaac attaagtgta gtacaaagtt tgttgattgc
     4321 tttatgggta gccgcggtta tgtcccgctg gttaggtgga ggagccacgt tgaccttacg
     4381 tttttctcct ttgatgactg gattagtcgt cgggttgatc atgggggaag ttgcacaagc
     4441 gatgattgtt acagccgctt tgcaaatgat ttatatgggg ggtttttctc caggaggatc
     4501 aatgccagct gaaccatcta ttgcagcagc tatcgcagta ccagtcgcat tattagggga
     4561 tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc ggattgctcg gaagttactt
     4621 gtatcagttt cgttttttca tcaatacttt tttaggtaaa tatacagaca aagctgtaga
     4681 agatttgaat acaaaagcta tggcccgatc aattattctt tatccaacgg ttgcctcatt
     4741 tttattattc gttccgcttg ttttcattgc tttatattta ggggcgccat tgatcgctga
     4801 tgtaatcaaa gctttagagg gaacagtcgt tatccacatt cttgaagtag taggtggagg
     4861 gttagcggca atcggtatcg cgacaactgt atacgttatc ggtcgaaaag attatctggt
     4921 ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa tctttagata ttacgatggt
     4981 tacttatgcc atttttggga ttattatcgc tttgatcttt gtccagtcgc aaaaagggaa
     5041 acaagtacag cctgccacaa gcaataacaa ttcagcatct tttgatgacg aagatgacta
     5101 tgatgacgga ttttaattta ggaggaatgg gaaatggctg aaataatgga taatcaaaca
     5161 ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag cctatctgag atggcatttt
     5221 gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc catcactact atacggaatg
     5281 atgccaatct tgaaaaaact ttataaagat gaagactctt taaaagcagc atataaacgg
     5341 cagttactgt tcttcaacac tcaattaagc tggggtggcg gtgtgattac tggcctaatg
     5401 tcttctatgg aacagcaaag agcagaagaa gagtatgaag aaaaagagat cttgatgcag
     5461 gatgacttga tgtataacac gaaagcggga ttgatggggg cactagcagg aatcggagat
     5521 gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa tcgcggtacc ttgggcacaa
     5581 cagggaagtc ctttaggcgc actttttcct tttatctgct ttgggttgta tcaggtttta
     5641 ctaggggtat ttttcgcaag acaagctttc actatgggcc gtaatgctac aggcctaatg
     5701 caaaacactg gtgttcagac agcgattgaa atgctatcag ttttagggtt gtttatgatg
     5761 ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat tgaaatttgc gatatccgga
     5821 cgtgagtttg ttatccagga aattcttgat caaatcgtgc cagggatatt acctttagct
     5881 gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat tgaaagtcac acaagcatta
     5941 ttatggctga ctggaatatt aattgtgcta gcaggaatcg gtattttata aaaagaaggg
     6001 aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg atgagcgttt gatccatggg
     6061 caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt ccatttttgt tgtagacgaa
     6121 gttgtagcaa aagataaatt tatgagagat ctttacaaaa atgcaggaag ccgtacagga
     6181 caaaaaacaa ttgtcattac accagagaaa gctaaattct attgggatga atatcaattt
     6241 aaagaataca attgtatttt gatcgcaaaa acagtccaaa cgatttacga cttagtaaaa
     6301 cacggaatcc ccatggaaga attgaatatt ggagggattg ctcaaaaaaa tcctgataca
     6361 gatcttttag tgacgaaatc tgtttattta aataaatcag atgctgaaaa attgaaagaa
     6421 atgaatgaac aatatggcgt aaagaatatt tattttcaag ccactccatc tgcacctaaa
     6481 acaggattaa aagatgtatt gaacaagttt gatttgtcat aaacaaatgc ttagaaaaaa
     6541 gataaagagg gcgaaaaaat gaagaagaac gagctgtttc gtgattggga atttcgttat
     6601 cgctatattt accgtaagcg ccgtacaaaa aagagtaaac agcgttttct ttcagcatta
     6661 gtatcagata tttacagtat gagaacagat gtgacagtca ttgcttacga tacgctagcc
     6721 taccgatcaa aaaatattta tgttggagat atcgaaaaag cagagaaagt tatctgtact
     6781 tattacgata cacccgttca tgcattagga agttatttca tgtttgattg gaaagaccaa
     6841 aggaaaaaaa caatctactc tatattattg tccttcattt tgttgttcag tttaggttgg
     6901 tggggaatga tgatatataa caaaaatcct catcacgtat tcgatctgct atccgtataa
     6961 acaggtatca ctgtactagc atttgggagc tactttttct tattgggaaa agcagctcgc
     7021 ggatggccta gcagacaaac ttttattcga aatacttcat ccatattaac gatgctagaa
     7081 atgatccgta cgattgatga tccgagtgta gcgtatgcgt ttgttgatga aggctgttat
     7141 ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa aagaggctat tcttttttat
     7201 ctagactctg ttggggcaga tacaccgcta cagttttcgg gaaattattt ttcaaataaa
     7261 gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa acgtcaatta tatttttagt
     7321 gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa cagatttacg agggaaaaca
     7381 tttaattggc aaaatgccaa tcagattatt gctctttttc gataagtaaa aagtgcaaaa
     7441 caaggagtga gaagactaat gttggaaatc atgatcgtta cacatggtaa gttgagcgaa
     7501 ggactgaaag atgcggcgga agtaattgtc gggacatcga gccatattga aacaatgtgc
     7561 ttagagtctg gggaggacat ccaaacattc ggagagaagg tcaaagaaaa attaactatg
     7621 atcaacacag cagaacccat gctagtattt gttgatctaa ttagcgcaag tccgtacaat
     7681 caagcgctct tggcagtcaa tgaactgact gaagaaaaga aagcagccac ttatgtcata
     7741 gggggcgtga atctgccaat gttgttagaa gcaatcaatc atcagatgct tcacacaccg
     7801 atagaagaag cggtggaaca aattgtcaaa caaggaaaag ataatttaac tgtttggcat
     7861 gcttcagcgg aagaaaaaaa attagatgag gacgattttt agaaggaagg ctgaaaagat
     7921 gaagtgggga tttagatggt atggtgaaaa aggggattcg atcccattaa aatatgttcg
     7981 ccaaataccg ggaataaatg ggataattgg aactttgctg actaaaatgc ctggagatgt
     8041 ttgggagatt tcagaaattg aggagttgaa agcatctgtt gagagccaag gactggaact
     8101 gcttggaatt gaaagtgtag cgatccacga tgcaatcaag gcagggacag atgaacgaga
     8161 ttactatatt gataactata tacgaacaat caaaaacttg tctcgatgtg gggttcgatt
     8221 gatttgttat agcttcaaac caatttttgg atgggcgaaa actgatttgt ttaatgaaaa
     8281 caacgatgga agctattctc ttttatacga tcagaaaatc gtcgatcaga tggagccagg
     8341 agaaatgtat caattgatac acagccagtc aaagggattc aaattgccgg gttgggaaga
     8401 agaacggttg aaaaaattcg ctcagctgga aaaactgtat gaaggaatga ccgaagaaga
     8461 attatttgaa aatctgactt attttttaga aaaagtgatt ccagtgtgcg aaaaagcaga
     8521 tgtaaaaatg gctatccatc cagatgatcc gccatgggaa ctttttggtt ttcctagagt
     8581 gacgaaaaat cttggcgact tgaagaaaat tctaaatgca gtagattctc catataatgg
     8641 actaacgctg tgcacaggat ctttaggggc aaatccggaa aacgatttag ttgaaatcat
     8701 ccatgaggta ggttcgcgca tccattttgt ccacttcaga aacgtggagt ttttaggaga
     8761 aagaaagttc aaagaaacgg cacatccctc tacagaaggc tcccttgata tgtatcatat
     8821 tatgaaagcg ttggtgcaag aagggttcga cggtcctata cgccctgatc atggtagaac
     8881 cgtgtggggt gaagtggcta tgcctggata tggcctgtat gatcgtgcaa tgggactcac
     8941 ttacatgcaa ggtctatatg aggcgataag taaggaaaaa ccactgggag agcattatga
     9001 ataaaatcaa gctcttcatc tttgatatgg atggcctttt attagaaact ggacgtttag
     9061 cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta tgaaatgcgt aaggaagtct
     9121 attatttact aactggccaa acagaaatgg cgataagaga acaaatgggc attttgtacg
     9181 gagaagatgt tccatatatc aaatggcgag aagcaatcaa tcaatataaa gaaaaaatcg
     9241 tgaaagaaga taagagagta tatacgaaaa aaggagcaga agaaatttta tcttttgcaa
     9301 aagaaagagg aatccataca atcgtggctt cgtctaatac acgggtaaaa gtagaaatgt
     9361 atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat catttcaggg gatgatgtaa
     9421 aaaaaggaaa gccggaacca gagatctttt tgaaagcttg ttcaaaaatg aatattcctc
     9481 caagtgaagc acttgtattt gaagactcga ttgcagggat cgaagcagca aggcgagcgg
     9541 gcattttgtc ttttctcatc aaagatcatt tgatagggtt gcccgatcat aatgggaagc
     9601 ataagttgaa agtagatgta agtttatatg aatccaataa agcagactat gaattttatg
     9661 acctgcatca agcaaaacga tttttagaaa gtaaagggtt gtatctctaa taaagaggac
     9721 tattttctag tcctctttat ttattgtcct gcacgactga gggaacagat gaaaaagaag
     9781 taatttttta ttttgaagta tctaccttat ttgtagtgaa caatttagaa caaacacaaa
     9841 acgcatctac tgttatctac cagtagatgc gtttaaagag aagaacgaga atcgtccata
     9901 tgagggtttc cactccttat gcagattttt ttaattcttg cactgcttgt tcgatcgtaa
     9961 cacctgtcgc tacatgattg gtattttctt tgtcaaaaac gacaaataga ttcaaatctg
    10021 tatccaaggt tactcgatat tgtatatctt tgttatagaa tgtcatagcc attctccttt
    10081 ctttaaatac ttgctgaaag gcaacgaacg cgttgataac gaaattccat ttataagtat
    10141 accaccaatt gaaaggtttt catagttaag aaattttaaa gtcaaaagtt gcagataaaa
    10201 gcaaataaac aagaaaacaa aaagtgaatc aatcgcggtt attcaacttt ttcttcgatt
    10261 cgaagacaat agaagacaat gaattttata tttcattgca ttatccttgt gttattagaa
    10321 aaagcatgat atattaaatg agtaatctat tttgaaacgt aatttgagcg atatatctac
    10381 atagataaaa ctccttttgc ctatcaaata tttattgcaa cgaaaaaacg tacattgata
    10441 cgtatcagga ggaatttatt tatgaataac ggtacagtaa aatggttcaa cgcagacaaa
    10501 ggttttggct ttatcactgg tgaagatgga aatgatgtat ttgcacattt ttcagctatc
    10561 caaggtgacg gcttcaaaac tttagaagaa ggccaagcag tgtcttacga tgttgaagat
    10621 ggtcaacgtg gccctcaagc aacaaacatt gttaaagctt aataaaaatt gacttttaac
    10681 cgtcttttcg aaagaaaaga cggttttttt gtacgaaaaa att
//
LOCUS       DARBDN010000087        10459 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000087 DARBDN010000000
VERSION     DARBDN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.088"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(160..645)
                     /locus_tag="SCH06_002231"
     CDS             complement(160..645)
                     /locus_tag="SCH06_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEG1078770.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    735..1080
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1125..1766
                     /locus_tag="SCH06_002232"
     CDS             1125..1766
                     /locus_tag="SCH06_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEG1078771.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            1785..2420
                     /locus_tag="SCH06_002233"
     CDS             1785..2420
                     /locus_tag="SCH06_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEG1078772.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2438..3253
                     /locus_tag="SCH06_002234"
     CDS             2438..3253
                     /locus_tag="SCH06_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEG1078773.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3572..5008
                     /locus_tag="SCH06_002235"
     CDS             3572..5008
                     /locus_tag="SCH06_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEG1078774.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5197..7644
                     /locus_tag="SCH06_002236"
     CDS             5197..7644
                     /locus_tag="SCH06_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEG1078775.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7874..8941
                     /gene="rlmN"
                     /locus_tag="SCH06_002237"
     CDS             7874..8941
                     /gene="rlmN"
                     /locus_tag="SCH06_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEG1078776.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9134..10237)
                     /locus_tag="SCH06_002238"
     CDS             complement(9134..10237)
                     /locus_tag="SCH06_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEG1078777.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         3452 a         1793 c         2278 g         2936 t
ORIGIN      
        1 aaatatggat ttggctaact atggaagaat actcgtatta gttttcagcg ttcatactag
       61 ttgttacatt gtttgattgg ccaaaagaat ttctgatata ttttgtgcta aataaagaaa
      121 aagacgcttg aattgggaaa taagaaaact actctatcat tacaaatttt cataaactgg
      181 cagatgttct aagtaaacaa gtatcttttc aaagtcggaa aaatccataa tcaacgtagt
      241 ggtattgata tttggatgaa agcctacggt atcttgacga tcaatagcag catcgatcac
      301 gacttggatt tttttctctt tgtcgtgcat caatgctaat ggagtcactg tacctgctgg
      361 aacgcctagg aggtcaggaa gctgttcttc agaaacaaaa gataagcgct tttcttttaa
      421 ttgttcagct agttgtttta aatcggcgtg cttttcatca ggcaagatga caagatagat
      481 ttgttttcct tttcttgatt tcaataatag attttttact tgcggaccag gtagggaaaa
      541 agggacattt ttgactgacg taatcgcagg atgatcgact ttttgaaaag agatacccag
      601 tttttttagt agttcataag cttcttgttc ggttgcacga ctcatcgcgc atcaccctcc
      661 tttttttatt agtgtatcat aaaaaagagt tgacaaatga aaaataatca tgtaaattac
      721 acgtaaagtt aaaacaaatg acatcgaaaa gaagagtagc cgttaggtgt ttttagagag
      781 tctctggttg gtggaaagag gcagcagtta accgtgaaac acatcttgga gtcgattttc
      841 tgaagcgtat agtaggaaaa tccggggagc ccgttacagc tgcggtcgtt gctagatgac
      901 cagataaggc tggcttttcc gtgaggagtc ggtaaaaaaa ggtggaacca cgtgattaac
      961 gtcctttgat cttcggatca aaggactttt tgttttcatc tgaacggcaa cgactgtgtg
     1021 aggttttttc tgcaaggaaa aaataaacag aggtggaacc acgtataata cgtcctcttg
     1081 gcatttgcca agaggatttt tttattttaa aggaggaaaa gaagatggag tatttgattg
     1141 aagttatgcc gcaattatta gtaggagcac tcacaacatt gaaattattt ttatttacct
     1201 tgattggctc attaccatta gggattgttt tagcattagg attgtctttg cattttaagc
     1261 cgctacgcta cttgcttcaa acatatgtat gggttatgcg gggaacaccg ctgttgttgc
     1321 aactgatttt tattttttat gggttgccga cgattgggat cgtttttgat cgtttcgaag
     1381 cagcactcat tgcctttatc ttaaactatg cagcttattt tgcagagatc tttcgtggag
     1441 ggatacaatc gattcctcaa ggtcaatatg aagcagcgca agttttgcaa ttaagtccct
     1501 ttcaaacggt gacgaaaatc gtcatcccac aagtgacaaa gattgtttta ccttctgtag
     1561 ggaatgaagt tatcaacttg gtcaaagatt cttccttgat ctatatatta ggtttaggtg
     1621 acgtaatgcg tgctgggaaa atcgcgatgg aacgcgacgc gactttactg cctttgctag
     1681 gcgtggcaat catctatctt acattgactg gtattctaac aatcataatg aaacaagttg
     1741 aaggaaaatt aaattattac cgctaactga taggaggaag aaatatgatt gaattgaaga
     1801 aagtgaacaa agcatttggt gaaaaaaaaa taatcaaaga tttgaatcta atcattccag
     1861 atgggaaaac attagctatc gtaggtcctt ccggtggcgg taaaaccacg cttttacgta
     1921 tcttggctgg cttagaaagt tctgacagcg gagaatttta tttagacggt gtaccgttca
     1981 acccattcga gcttaaaatg aaagaacaag ttgtaggagt cgtattccaa gacttccagc
     2041 tatttccaca tctgaatatt tttgaaaaca ttaccttagc accaaaaatg gtattgaaac
     2101 agacaaaaga agaatacacc aaaaaagcag aagaattagc ggcttcatta gggattagtg
     2161 atttattgaa tatctatcct tatcagcttt ctggcggaca aaaacagcgg gtagcgattg
     2221 ccagagcatt ggctatgaat ccacgggtat tggcttatga tgaaccaaca agtgctttag
     2281 atcctgaatt acgccagcaa gtcgagcgtt tgatcctatc attgaaagaa gatggggtaa
     2341 cccaaattat tgtcacccat gatttagtat ttgcagaaaa tgtcggtgat caattactaa
     2401 aagtttcccc aattcattaa gaaaggagaa gatagagatg aaaaaaacca gttttctatt
     2461 cgctttgatc gcaggtcttc ttctttttgc aggctgttcg aacaaaaaaa cttcagcaga
     2521 taattgggcg actatcaacg aagagaaaaa aatcgttata ggtttagacg atacatttgt
     2581 tcctatggga tttagagata aagacgggaa gctcacagga tttgatattg atttagccaa
     2641 agcagtcttt gaacaatatg ggattacggt agactttcag cccattgact ggtcaatgaa
     2701 ggaatttgaa ctgaacaatg gaacgatcga tttgatatgg aacggctatt ccaaaacgcc
     2761 ggcaagagaa aagaaagtgc aatttacaaa accttatatg gaaaacgatc aagtgctgat
     2821 cacacctaaa gaatcaggaa tcacaaactt tggacaaatg aataataaga gattaggtgc
     2881 gcaaaatggg tcatctggtt atgatgtatt tacgaaacaa ccagaagtat taaaagagat
     2941 agtcaaaaac caagatgctg ttttgtatga tagttttaat gaagcattga tcgatctgaa
     3001 aagcagacgg gtcgatggtc tgctgatgga taaagtatac gcagactatt atttgaaaca
     3061 aagaaacgaa ctagaagact tcaacataac aaaaggttct tatgagagtg aggattttgc
     3121 agttggtgca cgcaagtcag atagtacatt agtgaaaaaa atcaatgaag ccctagatca
     3181 actagagaaa acaggtgaat tccaaaaaat atccgataaa tggtttggcg aagatgttac
     3241 gccgagaaat taacaaatag gggactgtga caaaagacgt gtcacagtcc ctttttccga
     3301 ataaacagtg ttctcctgcc aactccttgt gactcggagc tgaatggcag gctcacaacc
     3361 tcttggtaaa cggtgttcaa aagccagttt ttcggtatta agccaaattt atgcaaaaat
     3421 gtagaaagcc attttcacaa aatttttctt actactcgaa actaagcgac tttttcacaa
     3481 cctcctttac ataattttat tttgttgtgg aaggggtttc gtgttattct aaaagaggaa
     3541 cgattgaagg ttataggaaa ggaagagatg aatggaacac aaagaactta cctcatttcc
     3601 aaaagatttt ctgtggggct ctgcttctgc agcgtatcaa gtagaaggag cttggcaaga
     3661 agatgggaaa ggagaatcag tctgggatcg atttgtacgg atacctggaa agacatttaa
     3721 aggaacgaac ggtgatttgg cagtagacca ctatcatcgt tataaagaag atattgcttt
     3781 aatgaaagaa caaggtctga aagcttaccg cttctctgta gcttggacac ggatttttcc
     3841 taatggacga ggagaagtca atcaagctgg gctcgctttt tatgagagat tgatcgacga
     3901 attgattgaa aacgatattg aacctatgtt gactttatat cattgggatc ttccacaagc
     3961 attgcaagat gaatataatg gttgggaatc acgtcagatc attgaagatt tcactcatta
     4021 tgcagaaaca ttatttgagg cattccgcgg gaaagtccat tactggatta gtttgaatga
     4081 acaaaatatc ttcacttcat taggttattt gttagcagca catccgccag gtgtgacaga
     4141 cccgaaacga atgtatgaag ttaaccatat tgctaattta gcaaatgcat ctgtcatcaa
     4201 taaatttcac gagttagaaa tgcctggaaa aatcggacca agctttgcgt atacgccaaa
     4261 ttatccaatt gacagtaatc ctgaaaatgt tctggctgct gaaaatgcag aagacctgat
     4321 ggccaattat tggatggatg tctatatgtg gggaaaatat ccgattgctg ccatgaggtt
     4381 cttagaagaa aaaggatggg caccaacgat tgaagctggc gatgcagaat tgctagaatc
     4441 tgctaaacca gattttcttg ggatcaatta ctatcaaacg gcgacgaatg cattcaatcc
     4501 attaaacgga gttggtgctg gaaaaatgaa tacgacagga aaaaaaggtt catcagaaga
     4561 aactggagtt cctggaatgt ataaaaaagt tgagaatcca tttgtcgaac gaacaaattg
     4621 ggactgggag attgacccag aaggattaag gatcggactg cgtcgtatca caagccgtta
     4681 ccgcatgccg gtactgatta cggaaaatgg cttaggagag tatgacaagt tgacagaaga
     4741 taaacaaatc catgacgact atcgaatcaa ttacttacaa agccacgtca aagccatcaa
     4801 agaagcaatt tcggatggag cagaagtcct aggctattgc acctggtctt atacagattt
     4861 gcttagctgg ctgaacggtt atcaaaagcg atatggattt gtatatgttg atcaagacga
     4921 aacacaagaa ggatctttgg aacgatataa gaaagacagt tattactggt accaaaaact
     4981 gattgaagaa aatggagaga acctttagtt cacatactta aaacaagaag gtacggctgg
     5041 atatggccgt gccttttctt gataaaatca tttagaaatt aagaaaaact gtaaaataag
     5101 ctgaaaaatg aaagaaagcg tcagttcttt caaacaaaac tttagttccc ttactttttt
     5161 ttgtataatg aaacttgatg aaatgaggga taataaatgg cacaaaagaa acggcctact
     5221 aaaaaaagga aaaagacgaa aaaaacgaaa aagcaaaaac agcagcagga acaaatgctg
     5281 acgattggtg ttgggtttgc cttgatttta tttgctgtct tcggcttttt aaaattaggt
     5341 tttttaggaa tattgattgc aaacggcttt cggatcattg caggaaatac ttaccaaatc
     5401 ctctgtcttt tattagccgt attaggattt tggattgtca ttaagaatac agagttttca
     5461 attggtaaaa accgacgctg gtttggcggc atactctttt atttcggtat cttattattg
     5521 ttacatgccc atttatttgg caaactccat actggggaac caaatatcat ggggacgaca
     5581 tgggatttgt tagccagtga tataaaacaa agtcaagtag acaataacgt tggtggtggg
     5641 atgattggag caatccttta tcattttact tacttcttga ttgcacagcc tggaagttat
     5701 ttagcagcag tgctattact ggcaggagga gcattcctgt tcagtaatct ggaaggctat
     5761 cagctgttaa atggtatcca atcaattgga gaacgagtac aggaattatt ggaaggtgat
     5821 cctgccaagc aagctcgaaa gcaagcggca aaggaagaga gaatgaaaca gcgcgcagaa
     5881 gcgaaagaag caaggcgctt agctgcaaaa gaagctgcag aaaaagaagc tgcagaatat
     5941 gagaagaaaa aagcggtgag ccagcaaagg gaaaatactg ctgatgaatg gcaggaacca
     6001 gaaaatacag agccggagca gctaagtttt gttccaatcg acagttttca agaaaatatc
     6061 catcctgcga atctagagaa accagtacca gatacaccaa aacagaccaa tacagcagaa
     6121 ggtttttcag atgagttgcc agaggatgac ggtacctcat tagaatttga gattgaagca
     6181 gaacaggaaa atcaagacta tgaattaccg acagttgatt tgcttgattc tataccaact
     6241 gtggatcaaa gtgatgagta taaaaaaatt gaaaaaaata tcggcgtatt agaacaaact
     6301 ttccaaagtt tcggtgtcga tgccaaggtc gtcaaagcca gcttaggacc atccgtcaca
     6361 aaattcgaag tccagccggc tgtaggggta aaagtaagta aaattgtgaa cttaacagat
     6421 gatatcgcgc ttgctttagc ggcgaaagat gtccggatgg aagcaccgat tccaggtaaa
     6481 tcactgattg gtattgaagt accaaatgga aagatcagta tggtttcctt tagagaaatc
     6541 atcgaagcac aaccaaacca cccagataaa ttactagaag tacctttagg acgtgatgtt
     6601 tctggacggg tacaaacggc tgatctttcg aagatgcctc acttactcgt ggctggttcg
     6661 actggtagtg ggaagtcagt agcaattaat gggattatca caagtatatt aatgcgtgct
     6721 aagccccatg aagtaaaact gatgatgatc gatccgaaaa tggttgaatt gaatatgtac
     6781 aacggcatac ctcatctgtt gacgccggtc gtgacgaacc ctagaaaagc agcgcaagcc
     6841 ttacaaaaag tagtacaaga aatggaagaa cgatatgaaa aattcgcggc aaccggagta
     6901 agaaatattt ctggttacaa tgaatttgtt caacagaaaa acttggaaaa cggaacgaaa
     6961 catccaacct taccattcat cgtagtgatc gtagatgaat tagctgattt gatgatggta
     7021 gccagcaatg aagttgaaga tgcgattatt cgtttagcgc aaatggctcg ggcagcgggg
     7081 attcatatga tcctagctac tcaacgtcca agtgtggatg ttatcacagg aatcatcaaa
     7141 gcaaatgtac cttccagaat ggcatttgcg gtatcaagcg gtacagattc tcggacgatc
     7201 attgattcta atggggcaga aaagctctta gggcgaggag atatgctatt cttgccaatg
     7261 ggtgagaata aaccgatccg tgtgcaagga gcattcattt ctgaccacga agtagaacgg
     7321 gtcgttcaat ttgttacaga tcagcaagaa gctcattatg aagagaaaat gatgccgaca
     7381 gatgaagttg aaacgacagg tgctccagaa cagccacaag atgagctgtt tgaagaagca
     7441 aaagcacttg tcgttgaaat gcaaacggca agtatttccc ttctccaaag aagatttcgg
     7501 atcggttaca accgagcagc acgtttagta gatgaactgg aagctcatgg agttgttggc
     7561 ccgtcagaag gaagcaagcc tcggaaagta ttcattgagc aggaagaaac atcagaaacg
     7621 ttgccggacg ataatgacat gtaaaacttg tgtgatgaag ggttgaaaaa cgaataacca
     7681 ataaaaagac aaggcatgat gataccaaaa gaaaaaatgg tttttttcca tcttttctaa
     7741 tacggtatga tgtcttgtct ttttagtttt tgtgagatta aagttctatt cgatttattt
     7801 gtgaagtatt gcattaagga aatgaatcat gtatagtatg tagcgaaact ttgagaaaaa
     7861 gagggaaaat actttggaaa aacagtccat ttatggcttg acgaatgaag aattaatcaa
     7921 ttggtttata gaaaacggcg agaaaaaatt ccgagctgcc caagtttggg aatggttgta
     7981 tcaaaaacgt gtaagtaatt tcacagaaat gacgaatcta tcgaaacaat tgatcgaaaa
     8041 attatcggag cattttatca tcaatcctct aaaacagatg gtcgtccaag aagcttcgga
     8101 tggtacagta aaatatttgt ttgaactccc tgataaaaac atgattgaga ctgtactgat
     8161 gagacaagaa tatggcttgt cagtttgtgt gacgacacaa gtaggatgta atatcggctg
     8221 tacgttttgt gcaagcgggc tgctcaaaaa gaaccgtgat ctgactgctg gagaaattgt
     8281 tgcacagatc atgatggtcc aacattattt tgatgagcgc aatcttggcg aacgcgtttc
     8341 acatgtcgtt gtaatgggga tcggtgagcc atttgataat tacgacaatg taatggactt
     8401 tttgcatatc atcaatgatg ccaaaggatt ggcaattggt gctcggcaca ttacagtttc
     8461 cactagtgga ttagcacaca aaatcaagga attcgctaat aacggcttgc aagtcaatct
     8521 ggctatttcc ttgcacgcgc cgaataatga ggtgcgaaca tcgatcatgc ggatcaaccg
     8581 aagtttccca attgagaaat tgatggaagc tgtggatgag tatttagaga aaacaaaccg
     8641 tcgaatcacg tttgaatata tcatgttgaa tcaagtaaat gatagaccag agcatgcgca
     8701 acaattagca gatctattaa aagataagaa aaaattagca tatgtcaact tgattccata
     8761 taatccagtc agtgaacatg atcaatattc tcgcagtcca aaagctgatg tattgagatt
     8821 ttatgatgta ttgaagaaaa acggcgtaaa ctgtgtgata cgtaaagaac atggtacaga
     8881 tattgatgca gcttgcggac aattgcgaag caagcaaatg aaaaaaacag ttgccaaata
     8941 atcgtatcct actcgttttt tcaattacca taaaaggagc agttttctta attaaggaac
     9001 tgttcaactt aaataagaga aaagattcta tagcgaaagc tataaagctt tttttgacaa
     9061 gaaaaaccct catcaagcaa agaaatgtcc tcaatttgat gacagcctgc ttgatggggg
     9121 ttttagcaat tatttaactg attttcttat atccttgctg gctttcttgt gtagcatgat
     9181 aagtttctac gtcaagaatg gcctgtttaa atttttctcg ggtgatttca taaggcacat
     9241 gtttaatatc atttgttgcc atggctttat ctaagattgc ttctaaatcg gtcgtgacat
     9301 tgagattcat gtcggttaac gatactggaa gttggttctt tttcataaac acatagattt
     9361 tatcaaacaa atcgaactgc tgatccatca tcaataaggt cagtacacca taactgacag
     9421 atgctccgtg aaggtatccc tccatttttt ctagaacagt cgtaccgtaa tagaatgagt
     9481 gtgccatagc agaattatag ttattgttaa ctaaaacaga aaccaatccg gtagtaacaa
     9541 tgatatccga aacgacttgt tcaattgcat atgagggacg atcgtcggca ctatctttca
     9601 atgcttgcgt accataagtc aagagacgat caatgcacat ttttccgatt tggattccta
     9661 atctatccgt gtagcctaga tcatcgccac gagcagaaaa agtagattcg acttctttgg
     9721 ataaagcatc gccaatacct gcccataagt atttatcagg tgcttcggca ataattgctg
     9781 tatcaatgaa ggtgtgtaca ggtggttttg aaggaaagaa gagtccgtcc attacgcctt
     9841 cttcgttata gatgacacat accgcagtga cgggcgaaca gttcgaacca atagtgggaa
     9901 aggtgaagac tggtttagct agtttttcac caatgacttt tacagtatcg caagcacggc
     9961 caccaccgac tgcaaacagg acgtctgctt tttggacact ttcatgctgg atcaactgtt
    10021 caatatttcc ataagttgaa ttacccccgt accagagact ggcgacaacc tctatttcct
    10081 gtgtcaaagc tacttttatt ttgttttctg cctttgaaag tgcagtcttc cctccaatca
    10141 gcactacttt tgtcccatat tctttgacga ttccatttgc tttttcatac gcatctgttc
    10201 caatggtata atttggtaag aaaacacttt gactcatatt catttccttc tttcttcgtt
    10261 gaaacgggtt aaaattttaa agagtgatcg atctgactgc ggctgtagat ggagtagagg
    10321 tgaacctaag acaggataag tgatgaataa ggtggcatga acaccttgaa atcatcaata
    10381 agtatcctaa aaacgaacaa gtacaaaaac attgaaaacg acaataatga atttttgttc
    10441 ctcttagtat ttctaccga
//
LOCUS       DARBDN010000088        10424 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000088 DARBDN010000000
VERSION     DARBDN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.089"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..612)
                     /locus_tag="SCH06_002239"
     CDS             complement(<1..612)
                     /locus_tag="SCH06_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078778.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINK"
     gene            complement(712..1221)
                     /locus_tag="SCH06_002240"
     CDS             complement(712..1221)
                     /locus_tag="SCH06_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HEG1078779.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(1422..2291)
                     /locus_tag="SCH06_002241"
     CDS             complement(1422..2291)
                     /locus_tag="SCH06_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1078780.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(2311..3432)
                     /locus_tag="SCH06_002242"
     CDS             complement(2311..3432)
                     /locus_tag="SCH06_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEG1078781.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(3434..3829)
                     /locus_tag="SCH06_002243"
     CDS             complement(3434..3829)
                     /locus_tag="SCH06_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEG1078782.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(3848..4654)
                     /locus_tag="SCH06_002244"
     CDS             complement(3848..4654)
                     /locus_tag="SCH06_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1078783.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(4647..5435)
                     /locus_tag="SCH06_002245"
     CDS             complement(4647..5435)
                     /locus_tag="SCH06_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078784.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(5449..5925)
                     /locus_tag="SCH06_002246"
     CDS             complement(5449..5925)
                     /locus_tag="SCH06_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078785.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(5997..8654)
                     /locus_tag="SCH06_002247"
     CDS             complement(5997..8654)
                     /locus_tag="SCH06_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1078786.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(8673..9077)
                     /locus_tag="SCH06_002248"
     CDS             complement(8673..9077)
                     /locus_tag="SCH06_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HEG1078787.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(9309..9566)
                     /locus_tag="SCH06_002249"
     CDS             complement(9309..9566)
                     /locus_tag="SCH06_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HEG1078788.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(9691..10023)
                     /locus_tag="SCH06_002250"
     CDS             complement(9691..10023)
                     /locus_tag="SCH06_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078789.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         3255 a         2111 c         1434 g         3624 t
ORIGIN      
        1 tttattaatt agttcatcgc ccaataatct ctccagtttc ttagcatctc ctgactcaac
       61 cggaattatc caagcccagt ctaaataatt ttttaaaatc tcatcatatt ttgcaaatat
      121 ttcattgcca tattccgtcc ttaaaattat attttcagtg ccagacaagt gatttatatt
      181 gagttgataa aaaagatctc catctaaaaa aatatcatta gaagaagatt tccccacagt
      241 aatgaccatt ccatcagctc tatgtgttac atacaaataa ttgtatgacc tcatttcacc
      301 taatgaatca attatttctt gccctttagc tctaatatat tgatctctat tacctatctc
      361 actcttattt aacaaaagtt ttttcatgtc aaatttaatc ggctgtttta tttttgtaaa
      421 ttcgcttcta ctactaatcc aatccgagat taatttttca acatgtccca gagtaaactc
      481 tgatttattc gctaaatact ttttttgttg tattaaagac atctttcccc gaagctcaaa
      541 attgagccta catcgattct ctatctcttc aaaaagcatc ttatcttcat cattcttata
      601 ttcatcattc ataaaaccaa tccagctcct cgattaagat aatattttaa tctcatacaa
      661 aaactagctc tcatcaaaac aaccattgtt ttgatttctc atgaaatttc tttatacttt
      721 tctccgatta taaattccta accccttgag aaaattacgc atatatttat ctccgcaagg
      781 cttaaaattt cgttggcctt cttttctcaa aaatgccccg atttcgcctt ttgatggata
      841 gatttctgcc tcagcaaaaa cgtctaaaat atcatcagtg gtcatagaca aggcgatttt
      901 taattttttt agcaacacat tgttgatata tttgatttcc ttgctttttt gcggcgtgtc
      961 tactatcggc ttatcttttt gcggaccacg cgccaagaga atcaggccat ttaggaatgc
     1021 gtcaaaaact tggttgttga tggttttttc atacacatta ttttctgcat tatctttgtt
     1081 cttatcctgt actttggtca gtaccgcctg agcttcttct ttagtcagtg gtacaccgcc
     1141 tagctcaaaa gctttaatca aatccgtatc tttcaaatca atcgcataac gcaatcgcaa
     1201 taacctatca ttgttattca tttgttcctc cgaagtattt agtctttact ttcttacgta
     1261 ctttttgtct tgctaagatt tttaggatca atgataaaaa ccgcatcact tatgataagg
     1321 cgctgggtat catgagtgaa tgatattgct gaatacaaat agtccgacca cattaagttg
     1381 atcggacttc ataagcattt tattgactaa tacttttttg cttaagaatt gattctaaca
     1441 tcttttgcta aagttaagca tcctatagtt cctgcattat ctgctaactt aggtgtgaca
     1501 atgtattctt cgatatttgg cgtatcgaca tagccgttaa ttagttctaa aaaacgtctt
     1561 tgtactttct ttttcagatg ttcttgttgc atgacaccac caccaaaaat tataatatct
     1621 ggtgaaagca tcagggtcgt attacaggca cattgtgcaa tataatccgc ctcgatttcc
     1681 cagaacggat cttctataga aagatcttgt cccttggttc ccgtacgcat ctcgatagcg
     1741 ggtccagatg ccaacccttc gagacaatca tgatgaaaag gacaagtacc agagaaagta
     1801 tctcctgaat gtctcttaac taacgtatgc cccatttctg gatggctaaa cccttcaaca
     1861 aaaatcccat cttgtatagc tcctccacca attccagttc caacagtgta ataaacaaca
     1921 ctggataaac cttttccatg acctgaaaca tactccccgt aacaagcagc attcacatcg
     1981 gttgtccagg caattggaat ttcgaaatgc ttattcaacg ttccaacaaa atcaaaattt
     2041 ttccaggcag tttttggagt agaggtgata tgtccatagg tctttgattc acgatggata
     2101 tcaatcggtc caaatgaccc tactccaatg ctttctaatt gttctttata gtgattaaag
     2161 aaatcaatta ccaaactcat tgtttcattc ggtgtagttg taggaaaact cactctttct
     2221 aaaaccttta aatcatcatt gccaatggca caaacaaatt tagtcccacc tgcttctatt
     2281 gagccataca tttcttactc caccgtcctt ttatctagga attcgttctt ccctgtctaa
     2341 tagtttttcg aaaaactcat gtggttcctt ttggtaccaa taggcaacag aagaaatatc
     2401 gtcttgacgc tcataaagct tgatgtcatc atttcctagg gtttggaaag taacacgtaa
     2461 attttctttg aaactaatgg ggtcgggtaa atgccagcgg tacaacccat gcatcggtaa
     2521 agcatcatcg ccaaaaccat gaactggatt tggattaggt tttccagcac taaaataatc
     2581 ccgggtgtga tctcttttag attgaaaagg atagcccata aatagcgtat taaaattttg
     2641 agcatatgcc ctttctccaa agttcttttt atggaaagcc caagcgccgc caaaataatc
     2701 ttctgctcct gtagatgtta ttgtagggaa atcttcatct ccatctatat aaaacttaaa
     2761 ttctccttcc ccccaccagt atctttccaa tgcgcacaaa gcaaagtagg ttcctacata
     2821 atacccagtg cctttgattc catcaataag ggtgtaatct tttccttttg tcgtgatggg
     2881 ttcacggttc catttagcat gaaaatacat cgcatcatcc ggtacttcag tcaatgcata
     2941 attaaatgta taaaaaatgt gcttaataaa ctcaggatgt tcattcgtta aagtaatctt
     3001 agcttttttt cgaaatggca tctcaaaata gcaattcatc cctgatgttg gattcactac
     3061 gattggtaag gaattcactt cgcatcttgt cccaaaccca ttacaaaaaa aatctcctaa
     3121 tggactttct acagaaggag tggattcatc atcccaataa atacgcaaaa ttaaatcacg
     3181 taagacgaaa ctcccagcga ttgttttgtc tgtcactgtc atccaaaaat gacgtaaaat
     3241 tccagggcct tccatttctg ctaaagtaat tgtctctcca gcatttatcg gaacagaagg
     3301 tgaccctttt ctcccaattc ctagatgact cgctgtcatt gccgctttcc ctttttcacc
     3361 atttttattt tctggtgaaa tagttctact ttcctctccc ttgtggagcc atatattatt
     3421 taaacaattc attttattcg tcctctatcc tttcttcact tttttgatta ttcatataga
     3481 tgatttgttg ttgtgcctcc gcaataattg ctccaatatc taaattatca tttcctaact
     3541 gcaaagcgat tgacattgcc aagggaagat tcattcctgc aattacgtgc actctgtcag
     3601 aaatataggt aaaaaacttt tgatttacac ttcctccagc catgtcagtt aaaacaatta
     3661 tttcgtctgt agtatccact aactctttaa tttgttcatc tatatcatca atttcttcga
     3721 catatgcaca taagctacta atttgattat gcatacctgt taaaaactct agtgtctctt
     3781 taaaaccctc agctagtatt gaatggctag caatgatcaa tcttctcata attcaaatcc
     3841 ttttccttta cgctaatatt ccaaatgcag ccataaccat cgcaaaaaca ataacgagta
     3901 gaatcaaaat ggtcatactg atttttttct tactgagtag ataatatgct gcagcagtaa
     3961 taattactgg aattaatgtt ggtaaaattt tgtccaacat tggttggatt ttcatactaa
     4021 cttcaccaaa agtgaattta agtggcgttg aaacactgat aactgaagca attaatgatc
     4081 caactactgt tagccccaat actgaagcag cttcagttaa ataattaatc ttttcaccgt
     4141 attcagtaac aatcttcatt ccctgcttat aaccaaattc aaagcctctc attcggaaaa
     4201 agaagattac catgattaaa atgaaccata aaaagattcc tacaggatta ttttctaaag
     4261 ccatataagc cgcaattgat cccatgatgg ttgggatcat cgtcatcaaa agagagtccc
     4321 caataccagc aattggaccc atcgtaccaa ctttaaagtc attaatcgca tcttttgctt
     4381 ctaatccttg cttttcctcc attgcaacac aagcacctaa aataatggct gccagccaag
     4441 gctgtgtatt gtaatactga aagtgattat ttaaagcttc gatgtattca tcatcatctt
     4501 tgtataattt tcttaaaata ggtgacaatg cgtaagtcac agatgcacct tgctgtgttt
     4561 gataattaaa ggtacaaact gacatcaacc aacgatagtt cgctttccta agatcctttt
     4621 tcgttacttg atatttttcg ctcattttat tcatcctccc caataaaccc aacatcagaa
     4681 gctcccgcag aagcagtgat ttgtgcatct ttttcagctc tatgatacac attaaatgct
     4741 aaagcgaatc ctatgatcgc cgctccaata ataggtacct tcaaaaaagc ggctaagaaa
     4801 aatccaacaa gtaaataact aatgtatcga cctgtaggca taaagcgtaa caacatcgca
     4861 ataccaacag caggcaacat ttttccggct aatgttagcc catccataaa ccaattaggt
     4921 aaaacatcca aaacgtaatt aacagcagac tgtcctaaag taacggcaat aaatactgga
     4981 attgctgcag ataaaccaaa gaaaattggc cccaaccaca aaacactatt cattttctta
     5041 aattctcgtt tattcgcata ttcctgtgat ttgcgaacaa caaaaccatt taagattttg
     5101 acaattacat ctagttgcac ccctaacata cctacaggta gtcctattgc taatccggct
     5161 tctactccaa gctggctacc aaatgccgtt gcaataattg cgcacgttcc atagtccggt
     5221 acagatgagc caccaaaacc ggcaactcct aatgacatca attgaactgt accgccaact
     5281 atcaaacctg tttttatatc acccatcaaa attcctgtga ataatcccca aaaaactgcg
     5341 taatttacaa agatcatcgg aatcccataa taatcaacat gtttaataaa tgctaatata
     5401 gtcagcataa taatttgaaa aatagtaaaa tgcattatcc ttactccttt atcctaattt
     5461 tgattgaatt tcctgtgcct tatccgccgg aacaaattgt gtaacaattt ctacaccaga
     5521 atccaacaat tttttatacg tgctgatatt ttcatctgat gcataggctc tagaagatag
     5581 ctgtaatgca ttatctttaa caacagtacc gccaacaatt agtcggtcaa ttctaatacc
     5641 gttatctact aaatgaagga ttgtttccgg ctctttcacg atgacaaata ctttttcctg
     5701 atcgtatttc ccctttttaa aattcgcaat cgctgtttct tcagtgataa ttgatacagc
     5761 cattccagca ggtctagcta aacgcatact tgatttttgg atgtcgttat ttgcgacaga
     5821 atcatcgatc accatcactc tgtttgcttt agacattggt gcccattgcg tgacaataat
     5881 cccatgcaat aaacggttat caactctcga cataacaata ctcataaata cttcctcctt
     5941 tatctttcat tttcttacaa gcaattacca tgccaaaaca aaaagaactt gataaatcaa
     6001 gctcttttta cataatcata aacgtattta acctcatgaa tcgggatgtc gacactataa
     6061 taatgttcaa cgacactgaa agattgctta aaatgtgtct gaaatttttg aaattcctca
     6121 ctcgtttcat tgaaataaat ttcatcttcc aaagtatttt gttttactaa tcgttcaatt
     6181 aagcaactaa tgtgaacata taatccgaaa cacgtattat tatcaaatga aattcctaga
     6241 tcattttgta agatgtatat agcatctgaa acccgttcta ataatttagt cggatttaat
     6301 atggtcaatt gctccattaa attcgttaga ctaaaattct tcagaatatt attgttcaaa
     6361 actttcagtt cattatcatt aaagtgtcta ttcaattgat tggagaattt acttatattc
     6421 attcctaaaa tcatatcttc aattgaaaag aattctacat cttctagatg tggatttagt
     6481 gttccaacaa taaaaagaat attgttctct ttacgaagct ccgataaata gttttcattc
     6541 actaaagagt aatagtcaca cgtttctatg acaagatcag tatcccttgg aaagctatct
     6601 tcaagtatct tttttaattt aaacgaagtt cctaatccgc ttgcacaaga acagacaatc
     6661 atatccttct taatatttga tgattcataa atataatcca cattttgatt ttcttttact
     6721 tgttcaagaa tctgtttaag cggtaaatct aataatatct gatttgcaac atcaatagcc
     6781 attcttgttg aaacattgtt tagtagtccg aatttttttt gagcgtctag ttccaaattt
     6841 agataaattt tctccagtga acccatatca acaagtaaaa taatttcttc atatccggta
     6901 cactcttgta agtatctatt aattttgtct gcaatctcac tacttgaagt cattagtggc
     6961 atatcaatgg cgtcgtatat atatctctca acgatcctat tagcagtact tgctatacag
     7021 gttgccgtta gatctccatg agccaaaatc agtgctaaac gtttttgctg aaattcttta
     7081 ctacacatta acttaaataa aataaccaaa acattttttt gaatttttgt taaataaata
     7141 tcccctattt gaataaaacg attgactaat tgaacttctc gactacacca actattaata
     7201 tcattgatga aggaatataa tttatcgtcc gatgttaatt ggatttgata aatccaagaa
     7261 ttcaaaaaga tagacgttat ttgaagataa taatagtcaa attctatttg aaaatctctc
     7321 tctatttcct taacatactg tctaaatcga atctcttgat aggtgggata tgttaaagct
     7381 gaattatttt ggatatcaac attcttttgt ctaaaatatc tatcatattt ctcaaaaagc
     7441 tgctgcttat cagtgtcttt cttccacgtt tgataaagat actctataag ttcgttgata
     7501 ttaaaaactt cgtctacttt ttccaaatca tccatttgaa tatattttaa ttcattctgt
     7561 cttttcataa ccttcatgcc gttgaaattc acccattgtg gtaaatgata catctgaata
     7621 taaagttctt ccaaatcatc taagaaataa aaggcattgg cacaggtcaa ttgaatgata
     7681 tttttcaaat tgccaacatt ttcactaaag cgatagttta ataaaaaatc taataattgt
     7741 tgagatatca gtattttctt tgctagtctt tcttcttctg atttaaaaaa tatcttgatt
     7801 aactgttttc tttcataaag agaacgactg tctaatgttg gaagtgttag ctttacaggt
     7861 attcttctca acaaagttga taatagttta tcctcaggtg gttctgatgt tgcaaatata
     7921 atccagcaac ttgatgtgta ccagttttca ttatcaccca tccgatgaaa tttcctcgta
     7981 tccataaact gaaaaagttt ctcctgacat tcattgctca atgcatgaat ttcatctaaa
     8041 aataagactc cattattagc taattctgct aaaccctttc ttccatcttc ggctcctgta
     8101 tatgcacctt ttacatgccc aaaaaaattg gacaagaaaa gttctggatt attggcatat
     8161 tcactacaat taactgaaat gaaagatgcc ttctcttcta tataattatt ggccaacaaa
     8221 tccttataca cataatttgc taaatagctt tttccagttc cagtctcgcc atgaagtaaa
     8281 atgggtaagc catttggcgg atagtagatt gctgctttaa tttgagcaat tacatttcgc
     8341 agacttcctt gacttccgat aaccctttct attccaaccc taaaagagct atcataccat
     8401 ttttccgctt cctctgaaga gctaaaaatt tgttgatttg gaactttctc cggtaaagaa
     8461 aagaagatta ctggacgagt attgattttt ccaaattctc catcttttac gaattcattc
     8521 aaatattgag agacaatatt acgactaaca tttaattttt cagatatttt ctgtgctgta
     8581 ttgttccccc atttattttt aatctcagag ttctctatga cataattgac aatgcgttct
     8641 tttaattctt ccatcacagc acctcctcga cactattcga attttgccga cagtattttt
     8701 ccataaatat gacttgctaa aaaggctttg tttagatcat tcaattggaa cgttgcttgt
     8761 tttgcttgat ccgctaagac gttgaaaaga tactctggcg aaatcgcata ccccaaaata
     8821 tcaacgattg ttgcaatcag atcttctttt gattcttcat ctgaaagtaa ttcacgatac
     8881 aacatcgttt gtttgcttac tgtgtcatat tcctctaagg attcatctgc taaaagaacc
     8941 acttgttcca acaaacggtc ggataaatat ttatagaaaa tcagccccaa taaataattt
     9001 ttatattctg acgcatccat tttactacgg agattatctg ccgcactaaa taacttctga
     9061 tttaattctg cacccaaaaa gatacactcc tatctcttat ttaaagttgc tatataccct
     9121 cttattttag catactcagt tttagaaaaa gcaaaaaaat aaagaaactt attcttgata
     9181 acaagctacg tgacgtatat ccctaacaca aaaatagcca tatcctttgg tttggatacg
     9241 gctatttgat attactcatt caattatcaa atcacagtag gtgtgaatct catcgggatc
     9301 ggcaatatct acttctgatt aggatcaaag gtgattttct caataaaggt gtgatacaaa
     9361 gctttaactt gcttcttctc actctggata agaaagcaat ccaaactagt caatatctgt
     9421 tggacatctt tgacttgaat cggttcccct tgttgttgaa agatccctaa gatttcattc
     9481 tctcgaattt gtaactgtct tcgtttttca gtcaattcat ttaaacgatc ttttaacatc
     9541 ggaaacaatt cgggactatc ttccaaagca gcttcctgtt tttgctctaa tagttagatt
     9601 ttgcgtacca ttttcttctt ttattttcct tcgattgctg attttaatat agtctaaagg
     9661 aaatttatat ttattgtatt ctttataact tcaagagaac ttcgtttgag tattactgta
     9721 tttttttaat tccataagaa aattagttat tacctgccac ctaatcagca aatctgaacc
     9781 tgagtcaata taattaatat tattttccat ctccaacatt gtaagtactg ttggtgttaa
     9841 tatagggact ttgtacaatt gtattttttt gattttatca tctgcacaaa ggagattttt
     9901 taaatctaat ccttctttta tttcaaaagt tgaatttttt aaatctataa gagtaaaacc
     9961 aattccttca tactgaattt ctgaaaatcg aatttttctc ccagttgata gatcaagggg
    10021 cagaaaacct tttattacat tgtgagtgtc accatcattt acaatgtcat taggaatttt
    10081 gattttagaa ttctgtggag cacctattgg aagataataa ttcattataa ttttgtagtc
    10141 ttcatgagga aataaagtac ttttaggatt gctaagatat tctcgtaccg aatctaagaa
    10201 tggcttatcc attgaatctt catccccatt taaactaaaa aacattccta caattgcttt
    10261 tgcaactcta agtgaattca ttttctttat tgaatgtgtt aaatcagact taccattctt
    10321 taaacttgta ttgttataaa ggaaattttt attgtcttct gcaaatctaa tatattcctc
    10381 aacatactca ctaccaaaaa aactattaca tttactacat aacg
//
LOCUS       DARBDN010000089        10192 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000089 DARBDN010000000
VERSION     DARBDN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.090"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            119..625
                     /locus_tag="SCH06_002251"
     CDS             119..625
                     /locus_tag="SCH06_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEG1078790.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            642..1541
                     /locus_tag="SCH06_002252"
     CDS             642..1541
                     /locus_tag="SCH06_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HEG1078791.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            1628..2512
                     /locus_tag="SCH06_002253"
     CDS             1628..2512
                     /locus_tag="SCH06_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEG1078792.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(2704..2775)
                     /locus_tag="SCH06_002254"
     tRNA            complement(2704..2775)
                     /locus_tag="SCH06_002254"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2740..2742),aa:Arg,seq:ccg)
     gene            2835..4169
                     /gene="rpoN"
                     /locus_tag="SCH06_002255"
     CDS             2835..4169
                     /gene="rpoN"
                     /locus_tag="SCH06_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HEG1078793.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            4318..5409
                     /locus_tag="SCH06_002256"
     CDS             4318..5409
                     /locus_tag="SCH06_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HEG1078794.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            5450..6451
                     /gene="gap"
                     /locus_tag="SCH06_002257"
     CDS             5450..6451
                     /gene="gap"
                     /locus_tag="SCH06_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEG1078795.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            6561..7751
                     /locus_tag="SCH06_002258"
     CDS             6561..7751
                     /locus_tag="SCH06_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEG1078796.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            7855..8610
                     /locus_tag="SCH06_002259"
     CDS             7855..8610
                     /locus_tag="SCH06_002259"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEG1078797.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            8726..10024
                     /gene="eno"
                     /locus_tag="SCH06_002260"
     CDS             8726..10024
                     /gene="eno"
                     /locus_tag="SCH06_002260"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEG1078798.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT         3565 a         1886 c         2112 g         2629 t
ORIGIN      
        1 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
       61 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
      121 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
      181 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
      241 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
      301 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
      361 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
      421 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
      481 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
      541 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
      601 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
      661 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
      721 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
      781 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
      841 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
      901 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
      961 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
     1021 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
     1081 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
     1141 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
     1201 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
     1261 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
     1321 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
     1381 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
     1441 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
     1501 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
     1561 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
     1621 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
     1681 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
     1741 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
     1801 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
     1861 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
     1921 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
     1981 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
     2041 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
     2101 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
     2161 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
     2221 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
     2281 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
     2341 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
     2401 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
     2461 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
     2521 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
     2581 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
     2641 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
     2701 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
     2761 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
     2821 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
     2881 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
     2941 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
     3001 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
     3061 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
     3121 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
     3181 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
     3241 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
     3301 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
     3361 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
     3421 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
     3481 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
     3541 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
     3601 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
     3661 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
     3721 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
     3781 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
     3841 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
     3901 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
     3961 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
     4021 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
     4081 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
     4141 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
     4201 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
     4261 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
     4321 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
     4381 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
     4441 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
     4501 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
     4561 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
     4621 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
     4681 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
     4741 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
     4801 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
     4861 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
     4921 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
     4981 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
     5041 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
     5101 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
     5161 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
     5221 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
     5281 atggcaatcg cgggcggaaa atcaaaagcc aaagcaattc gagcttatat gaaaaatgca
     5341 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
     5401 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
     5461 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
     5521 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
     5581 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
     5641 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
     5701 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
     5761 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
     5821 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
     5881 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
     5941 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
     6001 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
     6061 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
     6121 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
     6181 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
     6241 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
     6301 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
     6361 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
     6421 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
     6481 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
     6541 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
     6601 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
     6661 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
     6721 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
     6781 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
     6841 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
     6901 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
     6961 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
     7021 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
     7081 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
     7141 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
     7201 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
     7261 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
     7321 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
     7381 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
     7441 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
     7501 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
     7561 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
     7621 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
     7681 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
     7741 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgatcaa aaggtgaagg
     7801 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
     7861 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
     7921 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
     7981 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
     8041 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
     8101 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
     8161 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
     8221 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
     8281 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaagt gtcaaacatg
     8341 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
     8401 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
     8461 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
     8521 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
     8581 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
     8641 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
     8701 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
     8761 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
     8821 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
     8881 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
     8941 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
     9001 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
     9061 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
     9121 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
     9181 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
     9241 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
     9301 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
     9361 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
     9421 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
     9481 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
     9541 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
     9601 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
     9661 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
     9721 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
     9781 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
     9841 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
     9901 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
     9961 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    10021 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    10081 ttagttaagt aatcgaactc tctacttgct gaaatatcgg ctctttgtca ataaggactg
    10141 atgagttgtg caaaatcaaa tctgagtcag aatgaaccac attctggctc ag
//
LOCUS       DARBDN010000090        10086 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000090 DARBDN010000000
VERSION     DARBDN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.091"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(247..759)
                     /locus_tag="SCH06_002261"
     CDS             complement(247..759)
                     /locus_tag="SCH06_002261"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEG1078799.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(773..3070)
                     /gene="recJ"
                     /locus_tag="SCH06_002262"
     CDS             complement(773..3070)
                     /gene="recJ"
                     /locus_tag="SCH06_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEG1078800.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3212..3655)
                     /locus_tag="SCH06_002263"
     CDS             complement(3212..3655)
                     /locus_tag="SCH06_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HEG1078801.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(3656..4444)
                     /locus_tag="SCH06_002264"
     CDS             complement(3656..4444)
                     /locus_tag="SCH06_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1078802.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4441..5382)
                     /locus_tag="SCH06_002265"
     CDS             complement(4441..5382)
                     /locus_tag="SCH06_002265"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEG1078803.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(5559..6146)
                     /locus_tag="SCH06_002266"
     CDS             complement(5559..6146)
                     /locus_tag="SCH06_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HEG1078804.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(6367..7674)
                     /gene="obgE"
                     /locus_tag="SCH06_002267"
     CDS             complement(6367..7674)
                     /gene="obgE"
                     /locus_tag="SCH06_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEG1078805.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            7968..8978
                     /gene="gap"
                     /locus_tag="SCH06_002268"
     CDS             7968..8978
                     /gene="gap"
                     /locus_tag="SCH06_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEG1078806.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(9063..9998)
                     /locus_tag="SCH06_002269"
     CDS             complement(9063..9998)
                     /locus_tag="SCH06_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078807.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         2778 a         2298 c         1746 g         3264 t
ORIGIN      
        1 ttttacgggg gtgtgacaaa aatcggtcac atcctttttt tcgaataaac ggtgttctaa
       61 agccagtttt tcggtattaa gtcaaattgc ggaaaaagtg attttttaaa cttctactgg
      121 tctttgcttg tttccattta taaaaaaata gcgaccctca aaagtcagat agagaatctg
      181 acttttgagg gtcgctttaa aatcgcttct ttaagaataa catcaagaat agcttctttt
      241 ttctgcttaa tattccatta atgtaatgat gtcatatcct ttgattttgt cgcgtccatg
      301 gagatccatc aattcgatca aaaatgcgca gcctacgact acaccgccta attgttcgat
      361 cagttcgatc gtcgctttga ttgttcctcc agtagctagc aaatcgtcac aaatcagcac
      421 acgttgacct ggtttaatgg catccttatg caatgtcaat gtatctgttc catattctaa
      481 tccataagtc acttcgatgg tttctcgagg taacttccct tttttgcgga ctggggcaaa
      541 accgactcct aactcataag caacaggaca tcctacgatg aatccacggg cttctggccc
      601 aactaccata tcaattcgtt tttcttttgc ataatttacg atttgtttag tagcttcccg
      661 ataagcgtca ccatctgcca tcagtgggga aatatctcga aacacaattc cttttgacgg
      721 atagtcggga atactggcaa tataatcttt taaatccact ctttgtttcc tcctaggttg
      781 ttaaccattt ctttatggta ggaatatcgc tcaaaagcaa aaattcctca actttgattt
      841 tattgagccg tcgctggtat aatctgctct cagtcaaagg atgactttct gggctagcga
      901 ctttttgtaa aacaccgttc tctattgtaa caaatttcaa ttcaaaaaac acctgtatca
      961 taaaaattaa taatttttca gggatacgca aatattgagc tattgctttt attttatgac
     1021 gtatatcaat tcgttcttga gaatggatca atttaaacaa ttttgcgtac tgttctcttg
     1081 tgcctacccc attcaaatag gcctcatcag gtgaaatccc catcagataa acacgattga
     1141 atgaataaga ccgaaaaact tctttcagat ccgctaaatc atctggacaa tccataacaa
     1201 ctagagagtt tggttttctt ttttcaatta ttgcctttac agaatctagt ccttcgaaaa
     1261 caatcgcagc ttcctggata atctcaggca cgaatttcaa cgtcgaagaa tcaaatgcta
     1321 aataaaggct accttccgac gttcggctct gttcacggaa acgttttgcc cgccaatcaa
     1381 atacttgcag accacccaca gaaaaatcag ataccatcag ctgcggtttc ttacgcccgt
     1441 tccattcatt gatcgaaagc tttcctacca catctacctg attattcagc agttcttctt
     1501 cttgagtacc aaaaccaaaa gcgaccgcat caagctgact cgatgcatcg gaaaggacaa
     1561 atttcagatg ctgttggttt gctccgattc ttttgatatt ttctgcttgg acttgtcgaa
     1621 ataaaaactg aggcaaagga ttatccgtac caaatggcgc caatagtttc agctcatcaa
     1681 ttcgctctac tgttacttca tttggcagca atacttcatc aattctcaac tcaggccctc
     1741 tcatcaagtc aatttgatga tcgactatat attggttcat cttctcctgt agtatagtga
     1801 cattttcact tggcatcgtt aaaccgactg ctgcatgatg tcctccgaag taagtaaata
     1861 aatctcgcat ctggtcaagc atttcaaaaa gattcaaggc ttcaatacta cgtccagatc
     1921 ctttagctga tccatcttct tttaaagtaa ggacaagcgt tggtttaccc gtttcattca
     1981 ttattttccc agcaacaatg cccaaaacgc cttcatgcca tcctcggttt accaatagat
     2041 ggatatgatt ctccttattg accatcgcta atgcttcttg tgttatctgc tctacgattg
     2101 cttttctttc ttcattgatc tcattcaatt tttttgcttg aacggatgct tcctcttcat
     2161 caaacgtcgc aagtaacgag acggcaggac gtggatcgcc catccgaccg attgcattta
     2221 gtctgggagc aatcgaaaaa ccgatcgttg tttcgtctgc gtccctcatt tttacgccgc
     2281 tttcttcaaa tagcgcctga agtcctatcc gttctgaatg atgaatggca tcgattccta
     2341 atgaaacaag gattcgattc tcatcagtca atgaaactaa atcggcgatc gttcctatcg
     2401 ctactaaatc caaaaattct gcaggcggtt cttccaataa tgcagaagct actttgaatg
     2461 ctactccgac tcctgccaaa tctggaaatg gatagtgccc cgctggatga cgagggtgaa
     2521 caatcgcata agcgtctggt aaattctcag gtagttcgtg atgatctgta atgatcacgt
     2581 ctacaccagc ttgctgagcg tatgctaccg catcatttcc tgctaccccg ttatcaacag
     2641 tgatgatcaa ctggattcct tcttcgatct tttcttggta taccgattgg tttggtccat
     2701 acccatgctc aaatcgattt ggcaggaata cttctacttc tgcaccaagt aattccagtg
     2761 tttctttcat taccgttgca ctggtgatcc catctgcgtc ataatcaccg taaacgagga
     2821 ttttttctcc actgattaca gcttcttgga ttcggctgat tgctttatcc atatcgtgta
     2881 tcagatacgg atcatgtaat tcttgttcct ttggatgtaa aaatcggttg atatcctttt
     2941 cctcatggta acctctttgc cacagtaact taccgacaaa tggagataat ttcagttcac
     3001 ggatcatttg gagaaaggat tcagaaggct ctgtctcgct taacttccaa tcaaaatttg
     3061 cttgtctcac tttctcactc ctaacttagt tattatagca aaggaaatca gcaaaaaaaa
     3121 gcagaaagaa agaataaaaa cagatcagat ccgctagaca gatgttcagc aggacctgat
     3181 cttttgtacg accatttatg aaatatccct attagtcaaa ataattgaag ctttgtttgg
     3241 gcgattgagt tttttgttct tccggcgctt tcaattgact gatttgtgcg gttttcgctt
     3301 gtaactccgc ctgataagca gcttccaact ccgcacgttc gtttctaaac tcgcgttgct
     3361 gttcttcttt tgcttcttca attttctttt gaagttctgt ttgatattct gacatttcct
     3421 gagtcagctg tttgatttgc tttttttgct gccatagtgt tgccgaagca gtcaaaaata
     3481 caatcagtgc accaatcagc gcagaaccga tgatcactaa gatcaatggc gcagaaaagg
     3541 aagtgaagcc aaaacttaca ggaacatttt tattgttcaa tacagcaaaa agaacaataa
     3601 tcaaaactaa aacaaatcca agaatcacat tgctttgctt tttcaattcc ttcacctact
     3661 ttttgttaaa aattccgctg gctaaataat caccaatcgt tggaaacagc gtataaaatt
     3721 ttgatgcaac ttctaaaata aacggttgat tgatttcccg ttttggatgt ctcatattgc
     3781 ggacgatcat ttttgccaac ttggcaggtt ctaaaacgat ttgtccgact ttttccaaat
     3841 agcttccgct tggatcagcc ttatcgaaga aatttgtctc gattggacct ggattcactg
     3901 tcgtaacagc tacgccaagt ggtttcaatt ctaatcgcaa agcgttggag aagccaagga
     3961 ctgcaaattt cgtggcagaa taaaccgttg attttgcagt tgccattttt ccagccatag
     4021 aggcgatatt aatgatatga ccttgtcttc tttctgccat atcgatcgca aatttttgtg
     4081 tcaaaaccat cattcctaag atgttgactt caaacatatc gtatgctttt ccaaggtcga
     4141 atgtaaggaa gtcttcgaaa atcccaaaac ccgcattgtt taccagaata tcgacgcgcc
     4201 cgacttcttc catcaccttt tcatataatt cgtccacgct ttcaggattg ctgacgtcta
     4261 ccttgaaagc ataagcctct ttgccgctca agcgtctgca ctcgtctctg acaccttcta
     4321 caaatgccat tcttcgtgcg caacttataa cgattgctcc ttgctttgct gcttcataac
     4381 agatttgtgc gcccagaccg cctgaactac ctgttactaa aacaacttta tcttctaaat
     4441 tcatgcctct tcctcctcgc gaaatggaat ctcaatgcta tcaaaatctt tcataatcgt
     4501 cgtgttttca aacacttctt gtgcttcttt ttcaagctct aaagctgctt ttcctaaata
     4561 tctcgcactg atatgagtaa gtagcagccg ttttgcctgc gcttcttttg caacttcagc
     4621 agcttgatga gtcgtggaat ggaaatagtt gtgcgccatt cttgcttcat ctttattaaa
     4681 tgtgctttca tgtaccagaa tatcgctatt ttccgcaagc acaacggaat tatgtgtttt
     4741 tctcgtatcg cctaaaatag tcacgattcg tcctttttta tctggaccta cgaaatcttt
     4801 tccattgatc gtccgcccat cttctagttg gatcgtttca ccttgcttca gtttgccgta
     4861 cagtggtcca gctggaatac ctaattcttt tagacgatcc acctgcaatt ctcctttatg
     4921 atcatgttca accacacgat aaccaaaact gtcgatccca tgatttagtt tttttgtata
     4981 aacagaaaat tgctgatcag taaaaatcgg ggctgtttca tttagctcaa tgaatttcag
     5041 cggataactt aaacgcgttt gcgaaatacc taaagagact tttatgtatt cctctatccc
     5101 ttttggcccg taaatctcta atggcgtatc cccaccttga aatgaccggc tgctgatgag
     5161 cccgggaagt ccaaaaatat gatcgccgtg taaatgtgta atgaaaattt taccgatttt
     5221 tctcggacga atagtcgttc gcaaaatctg catttgcgtg ccttcgccac agtcgaacaa
     5281 ccaaacttca ttgcgctcgt ctaaaagttt caatgctata cttgtcacat ttctatgttt
     5341 tgcaggaaca cctgcacctg ttcctaaaaa ttgtaattcc ataatctacc tgactttctt
     5401 taagttcctc tttaatttta gggtaaaaag aagggataat caaccgtaag tcgagaatgg
     5461 gttcaaatta aaaataacgt tctaaagcga tagcgttttc tttgaaaatt actataaaaa
     5521 cagcagcgaa cccgtttgag atcctctgct gttttttatt aatttgaaga tccagaactt
     5581 tcattgtcgt tggaagtttg cggatgtttg tccttccaag tcttttgtgc agcttctttc
     5641 gcatgatttt cagcttcttt cgcatcatgc acatcttttt cgacatcttc ataatccaag
     5701 cgagtaattt ctccgcctaa ttccatcatt accaattgat tcagtgggcg attgtcctct
     5761 tcatcagcaa tcaagatcag tcctgtagct ccttcaccga ttttatttcc tacaaagtcg
     5821 aacacggtct gggcatcttt tatttctttg gcatcttgtg tcgcaccgat cattcctccg
     5881 gcaaaccatc ctaataaaat ccctagcgga ccacctaata caccaaccaa cattccgatt
     5941 aatccacccg tagaagattt gttattaccg gtaaagtcga taaaatcttc tattttgaat
     6001 tgatgtgtcc cattaggatc atggctgaca actgccatct gttctccttt aatcgaacga
     6061 acagcatgta actttttgat ttctgaaaat gcctgatatg cctggctttc tacttgaaaa
     6121 tttaaaatga ttactcgttt gctcattaaa aacgcccctt tcataccttc ttgttattta
     6181 ttttaccttt aattgaaaaa taagaaaaga aaagcactct ttttttccaa taaaataggg
     6241 ctgtgacaaa agtcgtatca cagctccttt ttccgaataa acggcgttct tgaagctgat
     6301 cacttctgtc acaacctccc ttaaatctga atctatattt tttggtattt gtttttattt
     6361 gcttgcctat tcgacaaatt caaattcaaa ctcaccgata cgtacaaggt cgccatcttt
     6421 cgcaccgcgt gcccgaagag cttcatccac acccatacca cgtaattgac gagcaaaacg
     6481 catcactgtt tcatcatgat cgaaattcgt catttggaat aatttttcga tcttctcacc
     6541 agataagatc cacgttgcat ctgaatcacg atcgatttgg aactcaggac cttctggatt
     6601 gaatccatag tgtacagttt cttcttccag ttcttcttcg tacaatggga attctggcgt
     6661 tacttctaac aaatctgctg tagcattcaa taacgcgtcc aatccttgtc gagtcactcc
     6721 agaaattgga aatactggga tgtcatcagc aaattcatct tctttttcct tgttcagctg
     6781 ttctttgaat ttcactagat tttccggtgc atccggcata tccattttgt ttgccacgat
     6841 gatttgcgga cgctctagca agcgtaagtt ataagtagat aattctttgt tgatggcaag
     6901 atagtcttca taaggatctc gtccttccat cccactcata tcgatcacat gtaaaattac
     6961 tcgtgttctt tcgatatgac gaaggaattg tgtacccagc ccaacacctt gcgaagctcc
     7021 ttcaatcaag cctggcaagt ctgctgcggc aaaacttctg ccatcacttg tagtaaccat
     7081 tcctagatta ggtacgagcg tcgtgaaatg ataagcgccg atttttggac gagcagatga
     7141 aataacggat agtaaagtcg atttcccgac agatggaaaa cctacaagtc caacgtctgc
     7201 caatactttc aattctagtt cgatttttcg ctcttgtcct ggttcaccgt tttcagcaat
     7261 ttccggtgca ggattccgag gagaggcaaa acggatattc cctcgtccac cgcgtccacc
     7321 ttttgccaca actagtgttt gaccattttc aattaaatct cctaaaagag caccagtctc
     7381 cgcatctcgg acagtggttc cttgtggtac tttaacatag gtatcttctg aaccacgacc
     7441 gtgcatccct ttactcatcc cattttcacc tggctgcgct ttgaaatggc gattgaaccg
     7501 aaaatccatc aatgtacgta acccttcatc gacgatcaag atgacatcgc cgccacgacc
     7561 accgtctccg ccagccggtc cgccgtcagg aacgtatttt tcgcgacgaa atgcaaccat
     7621 tccgtctccg cccttgccag ctttcacatc gatcgttact tgatctaaaa acatggacat
     7681 aattaagtcc tcctattatt catttattta tttgactgcc tgaatttcca caataaacaa
     7741 aagtcttact tattttatcg gtgaaatctg attttgtcta tcatttcagc aaaaagattg
     7801 tttaccttct tcttttttta tcatttggta aggtttccaa ccttttttct gctaccaagt
     7861 ataatttttt gacaaaatat tctttgcgta gcagaataac agtgtattaa ttgtattaat
     7921 tgaggatgcc gtttcacagc acccctaata aaggaggaac ttttgatatg acagtaaaag
     7981 taggtattaa cggatttggg cgtattggcc gtctggcttt ccgccgcatc aaagaagtct
     8041 cagatgatat tgaagtagta gcaatcaacg acttaacaag tccaactatg ttagcacaat
     8101 tattgcaatt tgactctact catggtactt atcctggcac agttactgca acagaagact
     8161 caatcgtagt ggatggcgaa gcaactcgtg tttatgcaga acccgacgca agcaaaatcc
     8221 cttgggcaaa agaaaacggt gtagatatcg tactagaatg tactggtttt tatacatctg
     8281 aagaaaaagc aaaagcgcat ttagatgctg gtgtcaaacg agtagttatt tctgccccag
     8341 ctggtgctat gaaaaccatc gtctataacg tcaatgatga tacattagat gaaaacgaca
     8401 aaatcatctc agcaggttca tgtacaacaa actgtttagc acctatggct tatttcttaa
     8461 ataatgaatt tgggatcgaa gttggtacaa tgacaacagt tcatgcctac acttccacac
     8521 aaatgctctt agatggacct gtaaaaggcg gtaatttgcg tgctgctcgt tcagctgctg
     8581 acaatactat cccacattct actggtgctg cgaaagcaat cggcttagtt atccctgagc
     8641 tacaaggaaa attacaagga cacgcacaac gtgttccagt cgttgatggt tcattaactg
     8701 aattggtttc agtattgaaa acaaaagtaa ctgctgatca agtaaacgaa gcaatcaaaa
     8761 aacacacagt tgacaatcct tcattcgggt atgatgaccg tcaaatcgtt tctagcgatg
     8821 tcattggaac aactcaaggt tcgatctttg acccaacgca aacagaagta acaactgctg
     8881 gtgatttcca acttgttaaa actgttgcat ggtatgacaa tgagtatgga tttacttgcc
     8941 aaatgattcg cttactagaa aaattcgcta acttgtaatt tgatagatca atcgataaaa
     9001 gaagcctttg actggatcca gtcaaaggct tctttctttt catcccctac ttttaaactc
     9061 gttcaatgaa catattggct taaaaattgt tggactactt gctgatattt ttcaggatct
     9121 gtcttgtatg cttccgcatg ctcggctcct tttacaacat acttttcttt tggtcccttc
     9181 gttgcacgat agaccttatc taacatttca aatggtacaa atgtatcttc gtctccatgt
     9241 ataaagagca ttgggcgctg gtttttcttc aattgttcca ctgcatttgc ttcaccgaaa
     9301 aagtagccag cacggacttt tgtcactaga ctcgttactt gcataagcgg aaatgctgga
     9361 agactaaaca tatcgtctag ctgataagca agctcatcat gaacggaaga ataaccgcaa
     9421 tcttcaatga ttgctttcac attatctggt agtttttctc cgctagtcat cataactgtt
     9481 gctgctccca tgctgacacc gtatagaacg atttcttgcg attttccatt gttttctagc
     9541 actttgttta tccactgtac atagtcttta cgctctggcc atccaaatcc aatgtaatcc
     9601 ccttcgcttt ttccatgtcc tcttgcatca ggaacaagga cattgtaacc catatcatga
     9661 aacatctttg cgtaattggt catcgtttca gcgtttccca tatagccatg agccacaaga
     9721 gctgtttttt cacttttcgt ttcagcagga agataaatcg ctgataattt cagaccgtct
     9781 tttgaagtga tggtccaatc gcttcggttt tcttttgaac taaaccattt atgtgcatcc
     9841 gtttctttgg atgtctgtgt tgtaccaggt gtatcttcgt ctaaaaagtc tttctcagaa
     9901 ggcacaacag cataattata aaaataattc cctgcaaaca ctaacgcaac aatcagagct
     9961 aaagcgacgc ctaaaaggat tttcatccaa agtttcataa atcatccatc tcatttctct
    10021 tttttcatat aaccttgaat tagtataatc aaagaatctc tactatgcaa tgttcatttt
    10081 tataac
//
LOCUS       DARBDN010000091        10084 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000091 DARBDN010000000
VERSION     DARBDN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.092"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            162..392
                     /locus_tag="SCH06_002270"
     CDS             162..392
                     /locus_tag="SCH06_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEG1078808.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="SCH06_002271"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="SCH06_002271"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEG1078809.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="SCH06_002272"
     CDS             1803..1979
                     /locus_tag="SCH06_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEG1078810.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="SCH06_002273"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="SCH06_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEG1078811.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2474..2941
                     /locus_tag="SCH06_002274"
     CDS             2474..2941
                     /locus_tag="SCH06_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078812.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3026..3910
                     /locus_tag="SCH06_002275"
     CDS             3026..3910
                     /locus_tag="SCH06_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1078813.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4024..4260
                     /locus_tag="SCH06_002276"
     CDS             4024..4260
                     /locus_tag="SCH06_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEG1078814.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4348..4428
                     /locus_tag="SCH06_002277"
     tRNA            4348..4428
                     /locus_tag="SCH06_002277"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4382..4384,aa:Tyr,seq:gta)
     gene            4435..4506
                     /locus_tag="SCH06_002278"
     tRNA            4435..4506
                     /locus_tag="SCH06_002278"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4467..4469,aa:Gln,seq:ttg)
     gene            4631..4801
                     /locus_tag="SCH06_002279"
     CDS             4631..4801
                     /locus_tag="SCH06_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078815.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5021..5728
                     /locus_tag="SCH06_002280"
     CDS             5021..5728
                     /locus_tag="SCH06_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1078816.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5788..6432)
                     /locus_tag="SCH06_002281"
     CDS             complement(5788..6432)
                     /locus_tag="SCH06_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEG1078817.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6559..6846
                     /locus_tag="SCH06_002282"
     CDS             6559..6846
                     /locus_tag="SCH06_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078818.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6954..7274
                     /locus_tag="SCH06_002283"
     CDS             6954..7274
                     /locus_tag="SCH06_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078819.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7355..8668
                     /locus_tag="SCH06_002284"
     CDS             7355..8668
                     /locus_tag="SCH06_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEG1078820.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8665..9384
                     /locus_tag="SCH06_002285"
     CDS             8665..9384
                     /locus_tag="SCH06_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEG1078821.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9512..10063
                     /gene="raiA"
                     /locus_tag="SCH06_002286"
     CDS             9512..10063
                     /gene="raiA"
                     /locus_tag="SCH06_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEG1078822.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         3359 a         1668 c         2151 g         2906 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcttattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2461 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2521 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2581 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2641 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2701 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2761 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2821 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     2881 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     2941 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3001 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3061 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3121 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3181 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3241 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3301 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3361 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3421 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3481 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3541 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3601 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3661 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3721 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3781 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3841 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     3901 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     3961 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4021 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4081 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4141 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4201 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4261 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4321 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4381 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4441 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4501 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4561 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4621 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4681 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4741 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4801 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4861 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     4921 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     4981 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5041 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5101 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5161 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5221 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5281 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5341 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5401 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5461 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5521 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5581 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5641 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5701 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5761 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5821 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     5881 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     5941 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6001 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6061 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6121 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6181 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6241 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6301 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6361 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6421 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6481 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6541 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6601 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6661 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6721 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6781 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6841 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     6901 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     6961 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7021 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7081 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7141 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7201 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7261 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7321 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7381 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7441 gatcgcagca gtggaacgtt tgggcaactg gattctttgt catcgctgtg gaatgaggac
     7501 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7561 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7621 agaagtcgtc tttttttgga caggacagct tactgaaaaa caaacggaaa tcgcaaagag
     7681 aatactttgc cattcagaaa aaagacatca tcttatttgg gctgtaacag gtgcagggaa
     7741 aacagagatg ctttatccta ttttagtgga aactttaaaa gctggaggaa gagtagcgat
     7801 ttgtacaccg cgagtcgatg tttgtaatga attgttttta cgctatcgtt atgtttttcc
     7861 agaagaaaaa atcacgttgc tccatgggaa tacagcaacg gcttatacct ttacttcttt
     7921 tgttatctgt acgattcatc agctataccg tttttatcgg tcctttgatt taatagtgat
     7981 cgatgagatc gatgcgtttc cttataacgg ggatgcagga ttagctcatg ctgtgcaaac
     8041 agcgattaaa ccagacggac gattcatcta cttaagtgcc acacctgata aaaagttact
     8101 aaaggaaatc aagcagacgt ttgacatcca caaacttgct ttgcgctttc atcggcgttt
     8161 acttcctgaa cccgtcttgg ttttcatgaa taattggcga caaaaatgca agaacaagaa
     8221 gaagataaaa tctttggtgc ggatcattca tcaattaatt aaagaaaacc atatcctttt
     8281 attttgtcca agtatcacga tgatgcatcg tttgaaagcc acacttcaag aggctcttcc
     8341 gagatatgag atcacagatg tttcttcaag agacaatcag cgggcggaaa aagtccagaa
     8401 aatgcgagaa gcaaaatatg acatactgtt aaccacgatg atccttgaac gtggagtcac
     8461 atttgaaaga atatccgtta tcgttttagg agcggatcat ccggttttta ctaaatcttc
     8521 tttggtacaa atcgcaggaa gagccgatcg taaagggcct tatacgaaca gtcaagtata
     8581 ctttttctat gaagaaaaaa ctgcagctat tcgaaaagct tgtcaggaaa tcaaagaaat
     8641 gaatgaagaa gggaagaaga tgctgtgagg tgcagttgct gcagtaaaga tatcgtccaa
     8701 aatttaacat tcagcgagat tattggtgtt tcgaaataca gattacctca gacttgttca
     8761 gtttgtcgcg cacaatttca tttattggaa acaagaggct gttctggctg tcaaaaacca
     8821 atccatttca atctagagag tacgaaaaag aaagtaaagt ctattcccgt ttactgcagt
     8881 gactgtcaag aatggaagaa gaaatatccg acctatgatt ttcagcaccg tgcctttttt
     8941 gtgtacgatg aaaatatgaa ggcctggctc aatcaataca agtttatggg agatatccga
     9001 ctagcaggca cctttgcata taaatggacg cagataaaaa aagaataccc gacatacatc
     9061 tattgtccaa tacctttatc tgaaaaaagg cgaacagaaa gaggattcaa tcaagtaagc
     9121 gagatgttga aagcagcaag aattcctttt cagatgctac tcaaaagaga gaagcatctg
     9181 ctggctcaag caaaaaacac gcgaaaggaa agattggaga tgcctcaacc ttttgaactt
     9241 gcagtcacct tttctaagat acaaaataaa aaaatattga ttattgatga tgtctataca
     9301 acaggacaga ctcttttcca cgcagcagat tgtttgcagg tcgcacagcc gaaaatcatc
     9361 cgaaccattt ctttagcaag atgaattaga tgtggaaatt tgatagcgat ttaatttgca
     9421 aataacctag agttcgatat aatagaatta agaagaggga aagagtggtc cttctccttc
     9481 ttgattgtgg tagacgaaag gggtaatttt tatgtttaga tataatgtac gcggcgaaaa
     9541 tatcgaagta actgaagcga ttcgcgacta cgttgagaaa aaagtaggca aactagaacg
     9601 ctatttcagt gacgcacccg atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa
     9661 aacagcaaaa gtggaagtaa cgatcccatt accttatctt gtattacgtg ccgaagaaac
     9721 ttctccagat ttatacgcaa gtatcgattt ggttgttgac aaattggaac gccaaatccg
     9781 caaattcaaa acaaaaatta atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc
     9841 tactgcttta ttcaatgaag aggacgaaaa cgaaaatgat tctgaattag atatcgtacg
     9901 tacgaaacgc ctttcattga aaccaatgga tagtgaagaa gcagtcttac aaatgaacat
     9961 gctgggacat aacttcttta tttttgaaga tgcagaaaca aatggtacaa gtatcgttta
    10021 ccgccgtaaa gatggaaaat acggactgat tgaaacagac tgatcagcct tacttaaata
    10081 acaa
//
LOCUS       DARBDN010000092        10023 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000092 DARBDN010000000
VERSION     DARBDN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.093"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(487..711)
                     /locus_tag="SCH06_002287"
     CDS             complement(487..711)
                     /locus_tag="SCH06_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078823.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            902..3679
                     /locus_tag="SCH06_002288"
     CDS             902..3679
                     /locus_tag="SCH06_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEG1078824.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3760..4179
                     /locus_tag="SCH06_002289"
     CDS             3760..4179
                     /locus_tag="SCH06_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEG1078825.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4191..4661
                     /locus_tag="SCH06_002290"
     CDS             4191..4661
                     /locus_tag="SCH06_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEG1078826.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4678..5457
                     /locus_tag="SCH06_002291"
     CDS             4678..5457
                     /locus_tag="SCH06_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1078827.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5444..6265
                     /locus_tag="SCH06_002292"
     CDS             5444..6265
                     /locus_tag="SCH06_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEG1078828.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6282..7331
                     /locus_tag="SCH06_002293"
     CDS             6282..7331
                     /locus_tag="SCH06_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1078829.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7344..8348
                     /locus_tag="SCH06_002294"
     CDS             7344..8348
                     /locus_tag="SCH06_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1078830.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8981..10000
                     /locus_tag="SCH06_002295"
     CDS             8981..10000
                     /locus_tag="SCH06_002295"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEG1078831.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3362 a         1651 c         2094 g         2916 t
ORIGIN      
        1 ttaatttgtt cttgcaatct tttttgctac gtaatttttg taaaaaagtg ggttgagaga
       61 aatctaattg attttcaaag aaggagtatg aaaatgagaa aaatatttat tcgtttattg
      121 tgggtactat cttagaggaa taaataatag tggagaaaac tatggtttgg cgcagattct
      181 atcaggtttg atggaacgaa gacaacctcc cgacatcaag tcaaaagcta cttgagattt
      241 tgatctgaaa ataaaaaaag aaaacaaggt aggaacatca atgtttctac cttgttttcg
      301 taatcaatgg gaaaaaacta agagtggtgt acgtaatcaa taaaaaggat ggtgacaaca
      361 gtacctcttt actctctgaa agcatcataa ctcgtttttc ctcattatgc caataaattg
      421 ttgttatacc acatataagg atttgtaata gctaaaaaca gacaggaaag ttgaaatctg
      481 tgaatcttat tttgtatgga aggatttata gaacgcaaaa atcaagataa agatgaataa
      541 aaatcctgtt tcggctatat attgcgtatc tacgccaata aaacgagttt gttctgtcat
      601 agccatataa agcaaaggca aaaatacaac tacagcgaga taagatccga tgatttctcg
      661 aaaagttttc caggaagtat gtttcctgtt tttatattta tccgatttca ttgaatagtc
      721 atagcctcct tattctttca tatgttgaaa ttccagtata aaaactggaa ggaactgtac
      781 gttttttaga ataaaaatta taagggataa gtaggctgct gtctataata agatatattt
      841 ttcaattctt tattaaagat tttattgaca aaatgaatcc gttttctatg atggaggagg
      901 ggtgaataag ttgttgaaga aggaaatttt atgttactta gagaaccaga cagccttttt
      961 cgatttagaa catatgaacg aggtctttac agcacaaagg ttagctgatc attttggggt
     1021 aaaaagaaac acagtcagtc attatttgaa ccagttaaat gatgagcaac tactagtcaa
     1081 aatcaattct cgaccagtga tttatttcca caaagaagct tttgaaaaac aattttttaa
     1141 gttacgcacg aatttttatt tttctatcga tgatctcaaa gaggaacagc cttttttcgc
     1201 gcaaccaaaa gacttattct cttttatgat cggatacgac gccagtttga aagaaagtat
     1261 cgaacaaatc aaaacagctc tttactatcc agatggcgga ttaccacttt tgattacagg
     1321 cgaaagtggc acaggtaaaa gttatttagt taatttggtc tatcagtatt gtctgcttca
     1381 tgatctgcta gaagattctg caccattcat cacttttaat tgtgcacaat atgcagataa
     1441 tcctgaactt ttgactagca atttgtttgg acatgttaag ggagcgtaca ctggtgcaga
     1501 agaaaataaa aaaggggctt ttgaagcagc agatggtggg atcttgtttt tagacgaggt
     1561 acatcgctta acaccagaag gtcaggaaaa actgttcacc tatcttgatc aaggtgtgat
     1621 ttatcgtatg ggagaaccta atttgtcacg ccggatcaaa acacgtctct tttttgctac
     1681 gactgaagag attactagtc atttcttaac aactttcatt cgaagaatac ctatccgaat
     1741 cgaactacct gcacttaatc agcgtagtcg taatgaacgg ctagaactga tttactcttt
     1801 ttttctcgaa gaacaaagaa aaatggggag ccctttgtca gtcagtggac cagctttgtc
     1861 acttttaaca agtcagaaat tatccggaaa cataggagag ctgaaaaata tcgtcaaagt
     1921 ttcagcagca aaagcatatg ctgaacagcg tgaacagcct gaaatccatg tcacgatcca
     1981 tcatttgcaa aaagaactac ttgcgcagcc tattactaaa aatacagcac agcaaggaat
     2041 ctatattacg caagaccaga ccttagagca attaatggag aagcaacagc ccgaacagca
     2101 gcgaatcgtt aaaagttttg agcaaatcct aattgatttc aagaaaaata actgtctgct
     2161 atattcttgc gaaggaaaat taaagcaaga agtgattcaa ttatttgatt ttttgctgtt
     2221 tgagaccagt agacaagaaa aacacgagct gctggtttat tggacacaat ctatccgaga
     2281 gacctttcga caaatggaaa ctgcctatca aatcaaattc gatggaaaca gtgtctatgc
     2341 cttgagttac tatctctatc agcgaagcac tatcaaatgg ttaccggaag aacatgatat
     2401 tatccaacta atcaaagaat tagaacaaca agtttctcag tcttatccat ctagttatca
     2461 ctatgtccaa cgaattctgg aattaagtaa gatcaaatta gatattgaag acacaagtat
     2521 ggatcggatt ttactgacga tctatctaaa aaaagcgaaa tggtcaaaag aaaaacgact
     2581 gccaaaagcg atgattgctg ctcacggtta tgcaactgct agcagtatgg caaatgtagt
     2641 aaatcgttta ttacaagagg atctatttga atcatttgat atgccactag atgtcacacc
     2701 acagcagatt gcttcagaaa tccttgatta ttgcgaaaac agcgatgttt caaatggatt
     2761 gatcatatta gtagacatgg gatctctgaa agaaatccat cagtttttta aaaaacagtt
     2821 atccgtaccg cttttgattt tgaataatgt gacgacacct ttagcaatca cagtagggga
     2881 atgcctgcaa aaaaatgtat cattagaaga gatagcagaa gagactgttc gacagatcca
     2941 gccagaatgg cgactgctct atccagagga aaacaaaccc aaagcactca ttactacttg
     3001 cttcactgga atcggtacgg cggtccactt aagtgaactg ctagaaaaaa gcttacctac
     3061 ggcttgtcag ttgaaaatca tcccatatga atatcagcaa ttaaaagata agaaaaacag
     3121 tgacccatta ttttccatat acgaagtcgt aggaatgatt ggcaccacag atcctgatat
     3181 caccaatatc gactatcttt cattagaaga cctcatctcg ggggaaaaga tgtctgtact
     3241 agctgaatgg ttggacacta ctatgaatgc ttcagagaag gaaatattca atcagcgcat
     3301 cattcgtaat ttttcattgg aaaaagtact ggattccgtg actattctag atacagagaa
     3361 ggtgatggga gaaatcgatc attttatgag agaattagag gtgcagttga atcgaagcat
     3421 cagcaatccc aaaaaattag cgttgtatgt ccatgtgagc tgtctcattg aacgattgat
     3481 ccgacaaatg ccaatcgaaa cctatcaagg attagagaaa tggaagcagt gtcaaaaaga
     3541 agggttatct gctattaaat ctgcgtttag tgtcattgaa gagcattata gtgtcatgat
     3601 ccccaattct gagattgcct atatctatga tattttgagt gaagatacag agtttctctc
     3661 gatagaagaa gaattttgaa cataagcaag ttgttgccac taattttggc atgcaacttg
     3721 cttttttagt atgtgtaagt gaaaagagga gatgaaaaag tggatagaga aattatctta
     3781 gcttcccatg gaaaatttgc ttcagggata ttagattcat tagagctgat ctatgggaaa
     3841 aatcattcta ttactgtatt cgattgctat actgatgaga attttgattt agcggaaaca
     3901 gtaaggcagc tttttatgag gtacaaagat aaagaaatca ttgttctgac ggatcttttt
     3961 ggcggaagtg tcaacaacga attcttacaa tatatcaatc gggatcatgt ctatctcgtt
     4021 gccggattga atttgccact attgattgag ctagtatctc ggttggacgc tgaagtagag
     4081 acaactgttt tgatccagca ggtgctaact gattcaaaaa aaatgatcca gttttgtaac
     4141 gagcggctca atcagaaaat agaagaagac gaattttagg aggaagaaaa atgattgtat
     4201 tgacaagagt cgaccatcgg ttattacacg gacaagtagc tttttcatgg acacaaacaa
     4261 taggcgcaga ctgtattttg attgctaatg atgatgtacc tacgaatgag atacgaaaga
     4321 caacgatcaa attagccaag ccacaaggag tcaaactagt gatcaaatca attgatgact
     4381 cgattgccgc gttgaaaagc ggggtgacag ataaatataa gttattcatc gtagtggaat
     4441 cgatcgagga tgcatataag ctggcagaag cgtatccaga aatcaaaacc atcaacttag
     4501 gagggatcaa ggcaaaacct ggtactcgca gcatcggaaa agcggtaaat attttaccag
     4561 aagaggagga acgcttgaaa cgattaattg acaaacaaat agaagtagaa atccgtcaag
     4621 taccagcaga taaaaaagtg gatgtaagag aagttttgta agaaaggaag aacctcaatg
     4681 attgtacaag cagtcttatt aggaattgtt gcatttgtcg cacaatcaga atatgcacta
     4741 gggacatcgt tgctttctcg tccgattgtg acggggctgt ttacaggaat cgtgttaggt
     4801 gatgtaaaaa ctgggatcat tatgggcgca actttagagt tagcatttat cggatcgttc
     4861 tcagtaggtg cttcgattcc acctgatgtt gtgaccggtg ggattttagg gacggctttt
     4921 gctattacag ctggagccgg tacagaaacc gcgcttttac taggtttgcc gattgctacg
     4981 ttgacattga tattgaaaaa tatttactta gggcttttga ttccaattat gaaccataaa
     5041 gcagacaatt atgcagaaga aggaaattat aaaggagtcg agcatatgca cttgcttgcc
     5101 ggtatcggtc tttccttgat gcttggtgtt gtggtaatgg tttcttatat ggtgggaagc
     5161 aatacgatcg gaaatctatt aaatatgatt cctgacttcg ttcaaaaggg gttgtcagta
     5221 gctacagggt tgattccagc tcttggtttt gcgatgcttg ctcgtttgct gatcaacaaa
     5281 caagttgcac catatttttt cttaggtttt gctatagctt cttacttaga gattcctgtg
     5341 accggagtag ctatttttgg tgcgatttta gcagttgtgg tagtcaatat tatgaatgtc
     5401 cgtcaactac cacttcaaac aactgcaggg gaggtagaag aagatgaaga attctgagat
     5461 caaaaacagc aaaataacga aaaaagagct aaatcacgta ttttggcgtt cttttcaaat
     5521 ggagttttct tggaattatg aacgtcagat gaatatggct tatgtttatg caatgattcc
     5581 gattttgaaa aagttatatc agtcgaaaga agaaatggca gcagctttga aacggcatct
     5641 agagtttttt aacacgaccc cacatatcgt tacactgatt ttaggaatca cggctgcaat
     5701 ggaggaagaa aataaggatg atcctgaatt tgatgtgact gcgatcgata gtatcaaaac
     5761 atctttgatg ggacctcttg cagggttagg agattctttc ttttggggaa ctttgcgatt
     5821 gattgccaca ggtgtgggta cctctttagc catgcaagga aatattttag gccctatctt
     5881 gttcattttg attttcaata ttccgcacat tctgtttcgc tatctagcaa caggttgggg
     5941 atatcgctta ggaacgggtt ttttgaaaaa gatccaggca aacggtatga tggaaagttt
     6001 gacattaggc gcgtctatta ttggactgat ggtcgttgga gcaatgactg ccacgatgat
     6061 caccatcaat attcctttaa aaatcggttc aggagaaaat gctgtgactg ttcaaagtat
     6121 ttttgatgat atcgttccaa atatcttatg tcttggagca tttggcatag tgttttatct
     6181 attgaagaaa gaagtgaaac cattaacgat cttgatcgga ctagctttct ttggaatttt
     6241 tggttcgtgg atagggattt tttaaaaaag gagcagagaa aatgtttacg atgcaagatt
     6301 atatctatga agaaaaggaa gtactaagta cgatcttgaa aaagaatgat ttttcgacaa
     6361 gagaacatat gaaaaaaaca gtgaatttac tgatcttagc aacgggttca tcttataacg
     6421 cttgtttagc agcgaagcca gcattggaat cttatggtga tcttactgtc gatattcaag
     6481 aaccttttta ttttttcaat tatggaaaac tttctccttc aatcgatact gtgattgctg
     6541 tgtcacaaag cgggaaaagt gcttctactg ttgaagcagt aaaaatgata caaaaacaag
     6601 ggttacctgt tgttgctatc acaaatgacg tgcaaagtcc acttgcttta gaagctgcac
     6661 aaattattga tttaggtgcc ggggtagaat cagtaggctt cgttacaaaa ggctattctg
     6721 cgactgtttt acagttacta ctcttaggga taggaattgg aataagtaaa aataaaatca
     6781 gcaaaaaaat agaacaagac tacatgcaac agttgcgcaa aataatcaac catttaccag
     6841 cgattattca aaaaacggaa gaattttttg atggatatca aagtttattt cgtttagcac
     6901 agcgtttcgt caccattgga tatggtccaa actggggaac agctaaagaa gcagagacga
     6961 aattgactga aacaatccgc gttccgtcac aaggatttga gttagaagct tatatgcacg
     7021 gcccatacct ggaggcagat gcttcgcatt tgctattctt tattgaaggg gaaagtgtaa
     7081 ataaggaacg ttcgcaaaag ttgcaaagat atatgagtcg gtacgttgga gagactctca
     7141 ccattaccac aaaaaaagca agaaacgaga aaacacttgg attagcaata gaatgtgatg
     7201 aatatctgtc tgtattagcg cttgtcgttc cgtttcaact attcgcttat aaaaccgcag
     7261 tagctaaagg tattgacttg aacaaaaaga tttttgaaga ctttgataca gtcttgaaaa
     7321 gtaaattata agaggtggaa atcatgctga aattcaatga agaagaacaa atcaaagcaa
     7381 taaaaggcgc actagcttta cgtccgcaag tagaagaaat catcgataaa ctttatgcgg
     7441 aaaaatttga cgctgtctat tatctaggaa tcggtggaac gtatgcttcc tcgatgcaag
     7501 ctgtcactta tatgaatggg aaaagcaact tgcctgtctt tgtacagcat gctgcagaat
     7561 attacactac tggaaacaaa agattaacaa aagattctat cgttattttg tcctctgtta
     7621 ccggtacaac tcaagaagta gtgaaagcag tagaacaaat caagaaagta ggagcgacac
     7681 tgattggatt tatcgataaa gcgaacagta agttgtctca gctatgcgat tttgtggtca
     7741 cttatccagc tcctggaaca gaacaaatca aattttttat ggcagcagat cgattgatgt
     7801 atttgaatgg agaattcgaa gcttattcag aatactatga acagctcgaa cgttatttac
     7861 caacagggtt agtggaagca gagaaaaaag cagatgcatt tggcttatca tttgcagaaa
     7921 aacatcgacg tgatagtatg cattatttta ttggagcagg gaatcaatgg ggagctgttt
     7981 attcatatgc catgtgttac tgggaagaac aaagctggct tccatcgaaa tctatccatg
     8041 ctgccgagtt tcttcacggg acgttagaga tcgtagaaga aacaacccca gtcacattat
     8101 ttttaggcga agatgaacag agagtgttat ctgaacgtgt ggctaaactt ttgccaaaaa
     8161 tttgcagcaa ttatacattg atagacacaa aagactatcc agtagaaggt atcagtgaaa
     8221 aatatcgcgg acgtgttttg tctttcttat tgatgcatgt agtgacacaa cgcatcgatg
     8281 ctcatgtgga gcagttgaac tgccatccat tagagatacg ccgctactat cgtcagtttg
     8341 attattagga tagactggat aaaaagaata taaaaaataa agagagcagc gataactgct
     8401 ccctttattt ttttaaaata ttggcatcaa ttacgttata aaacacattt tttgcattat
     8461 ctacagttca acttataatc tgtttaatgg gacatgtggg tgccaaccat tttttgttat
     8521 gcaatagtac tatttagttg ttgcatggat ccgtagtaaa agtccaagta caacgagttg
     8581 cgccagttta catagcgttt tgtatccaga atgttgacta aaacaaaagt tcctatgtca
     8641 accgtcaaca gagacaatct gtccgttgca ggacctgaca gatttagaaa tgttcaatct
     8701 gtctcttatg tattttaaat caatactcac taggagaagt ttcctaacct cctaatagta
     8761 atgctggtag taacattgtc aaaactgctt cctcttagga acaagcaaag cataacgagt
     8821 gtaaaaataa aatgtagact attgtaacat atcattgatt atttcaagta aaaacgataa
     8881 aagaagtaaa caaacactta aaaacaatgg aaattagtcc caactttaag aaatgtatac
     8941 tataatggaa attatcaatt atttatttgg aggaatatcc atgaaacaaa aaatcgcagt
     9001 tcttggtcct ggatcttggg gcactgcttt agcacaaaca ttggcagaaa acgggcatga
     9061 tgtccgtatt tggggaaatg tacctgaaca gattgatgaa atcaataagt atcatacaaa
     9121 tcagcatttt ttacctgatt tgacgatccc agaatcgatt atcggatata aagaattggc
     9181 agaagcagtg gataacgcag atgctatttt atttgttgtt ccaacaaaag cgattcgttc
     9241 agtcgcacag gaacttattg gtaaaatgaa tactaagcca atcattatac atgcaagtaa
     9301 aggactagaa caagatacgc ataaacgaat ctcagaagtt ttggctgaag aaattccaga
     9361 agaaaaaaga caggcaattg ttgtattatc tggtcctagc catgctgagg aagtggcagt
     9421 acatgatatc acaacaatta cagctgcaag tattgatcaa aaagcagcag cctatgtaca
     9481 aaaactgttc atgaatgatt atttcaggat ttatacaaat aatgatgtga ttggcgtaga
     9541 aactggtgca gcactgaaaa atatcattgc aattggtgcc ggcgctatcc atggattagg
     9601 attcggagat gatgcaaaag cagcaatcat gactcgagga ttggcagaaa tcagccgtct
     9661 tggtgtcgcg atgggtgcca atcctctgac atttatcggt ttgagtggtg tgggggactt
     9721 gatcgttact tgtacaagtg ttcattctcg caattggcgt gccggtaact tgttaggaca
     9781 gggacataag ctggaagaag ttctagaaaa catgggaatg gtcgttgagg gtgtggcaac
     9841 gacaaaagca gcagtagagc tagctcaaca gctaggtgtt gagatgccaa ttactcaaac
     9901 aatctataat gttttgtata atggagaaga tatcaaaaaa gcagcaaaag aaatcatgtt
     9961 acgtgacgga aaaatggaga atgaattttc tcttcgttaa atagatgatc aatagttaat
    10021 cgt
//
LOCUS       DARBDN010000093         9941 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000093 DARBDN010000000
VERSION     DARBDN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.094"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            124..3351
                     /gene="fss3"
                     /locus_tag="SCH06_002296"
     CDS             124..3351
                     /gene="fss3"
                     /locus_tag="SCH06_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEG1078832.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            3464..3778
                     /locus_tag="SCH06_002297"
     CDS             3464..3778
                     /locus_tag="SCH06_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1078833.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3791..4165
                     /locus_tag="SCH06_002298"
     CDS             3791..4165
                     /locus_tag="SCH06_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1078834.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            4175..4510
                     /locus_tag="SCH06_002299"
     CDS             4175..4510
                     /locus_tag="SCH06_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HEG1078835.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            4593..5933
                     /locus_tag="SCH06_002300"
     CDS             4593..5933
                     /locus_tag="SCH06_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEG1078836.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            6011..6685
                     /locus_tag="SCH06_002301"
     CDS             6011..6685
                     /locus_tag="SCH06_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEG1078837.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            6678..6842
                     /locus_tag="SCH06_002302"
     CDS             6678..6842
                     /locus_tag="SCH06_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078838.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            6918..8060
                     /gene="dcm"
                     /locus_tag="SCH06_002303"
                     /pseudo
     CDS             6918..8060
                     /gene="dcm"
                     /locus_tag="SCH06_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            8050..8340
                     /locus_tag="SCH06_002304"
     CDS             8050..8340
                     /locus_tag="SCH06_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078839.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            8599..9783
                     /locus_tag="SCH06_002305"
     CDS             8599..9783
                     /locus_tag="SCH06_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEG1078840.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            9780..9917
                     /locus_tag="SCH06_002306"
     CDS             9780..9917
                     /locus_tag="SCH06_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEG1078841.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT         3291 a         1679 c         2247 g         2724 t
ORIGIN      
        1 taggctcatt cattctcaaa tccattctat tcagtcaata aaaattttaa aaagacttta
       61 taaacaaaga tgttcaagcg agcatcttat ttttttgtgc ttaatttgaa aggagaacat
      121 ttcatgtata aaaaacaaaa aaagaaatta tgtgtattaa ctattttgag tttggctgtt
      181 caagcaattg ttggagcaat tgctcctacg attacttttg ctgatgaaat tacccatcca
      241 caaacggtaa ccgtagaact agatttagca catcaatatg ctgttgaagg aacttttagt
      301 gatggtcgtc caatgtcaga agtcactgtt ccgcattatg cagtgtacaa cggctttaaa
      361 caagatattt tctgtattga accaggagtc ccgatttaca atgagttcac tcctggctat
      421 gagaaaaacc cgttaccaga tatgtccgat aaagccaaat tagtttccgt tttatggaaa
      481 aaagtaggta cagatgcaga tactcatatt gtggcacaga agatgatctg gcaagaagtt
      541 aatgggtata cccttcactc aataaaacga tcagatggta gtgccgtaaa tatcgcagcc
      601 attgaggcaa aaataaatca agccattgac gattatcaga agaaaccaac cttccataat
      661 agtacggcta aaacagtatt agggcaatcg actactgtga cggatacgaa taatctgaat
      721 ttgtcagagt tcgatgaggt tgtggaaaat gccgcaaaca ttgattatcg tgtgaatggt
      781 aatcagttga taatcacccc aaatgccaat tcaaaagaaa gtggtgtgct gacgcttaag
      841 aaatctgctg gtaccggaac acctgtcgcc tataaaaagg ctggccaaca gactttaatg
      901 gccggggcga ttgataaacc taatacctac acaatcaaaa ttgatgtgga aacggagggt
      961 tctttaaaga tcaaaaaagt cgataaagaa tcgggtgatg ttgtaccagg aacggttttc
     1021 catttagact ttggaaaaac tttacctgca aaagacgtga ctactgacaa agaaggcatt
     1081 gctacattgg atgagattcc tcatggtaca aaagtaacca ttaccgaaaa atcagtaccg
     1141 gcgccttata cgattgatac cacccccatg actaccacca ttaaagcagg cgaaaccatt
     1201 tacgtgactt caaaaaacgc acgggaaaaa gggcaaatca ttctggataa aagcggagtt
     1261 gaaacaggga gtgatctttg gaatgacaat tattccttag ctggtaatac gtttgccatt
     1321 cgcaaagaca gtccaaccgg tgaaatcgtt caagaaatga ccacggatga aaacggtcat
     1381 gcggaaacac caaaagagat tgctaatgcg ttggaattgg gaacctatta tgtgaccgaa
     1441 actaaagcta gtcatgggtt cgtgaatacg ttcaaacctg taaaagtcga attgaagtat
     1501 gccaatcaaa ccgtagcccc tgttaccagt aacgtaaaag ggcaaaatca agaagtcact
     1561 ggcgaaacca ctttgacgaa agaagacaaa gatactgggg ataaagcaca aggtaaggca
     1621 gtctttgagg gtgctgaata caccttgttt actgctaagg atggaaaagc tgttaaatgg
     1681 agtgaggctt ttaaaccaga gttagcgaag ggaacgaaag gttctgatga aacggtcact
     1741 ttgactttag acgaaaagaa ccaagttgcc gttaaacatt tagctatcaa cgagtattat
     1801 tggcaagaaa caaaagcgcc cgaaggatat agccttgatg aaacaaagta tcctgtatcc
     1861 atcaaaaagg tggatgatag cgaaaaaaat gccgtgatta cccgaaatgt tacggcaaaa
     1921 gaacaagtga ttcgctttgg ctttgatttc tttaaatttg ctggatcagc tgcgggcact
     1981 accgaaactg gcttcaatga tctgaccttt aaagtgtcgc cattggaagg gaccaatgaa
     2041 atcacaggtg ccgaagatga agcgaccaca gcttataacg agcaattagg gtttgatggt
     2101 tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt agaagcccca
     2161 gaaggttttc aaaagattac gccattagaa atccgttcta cttttaagga aaacaaagaa
     2221 gactttgtga agagtgagta tgtctttacc attaccgaac aagaccaaaa acaaccaatt
     2281 aaaacggtga ccgttcctta cgagaagctg acgaacaaag cattttctgt tagtttgaac
     2341 cgtttaatgc tctatgattt gcctgaggaa gaagatagtt taacttctct tgcgacttgg
     2401 aaagacggaa acaaagaatt aacttctctg gattctaccg agctagttga taaattgagt
     2461 tacaatctac atgaaatcaa agaagactgg tatgtggtag cgcaagccat tgatgtggat
     2521 gcgacaaaag ctgcccaaga aaaagatgaa aaagccaaac cagtggtgat tgcagaaaca
     2581 agcgcaacgt tggcgaacaa agagaaaaca ggaacttgga aaattcagca taaattaacc
     2641 gccgaacaag ttttaaataa aactattgtc ttattcaact atgtgtatga aaataaggaa
     2701 gcttttgaag caggcgataa gccagtagcg aaggatgtta gcttgaataa ccaagcccaa
     2761 actgtcagtt gtacagtgga acaccatgtt tctatccaaa caaaggccca cctagaaaac
     2821 ggttctcaga cctttactca tggtgatgtg gtggatatgt ttgatgatgt gtcgattact
     2881 catgatgtac tggatggctc aaaagaagct ttcgaaacaa ttctgtatgc tttattaccg
     2941 gatggtacaa acaaagaaat ttggaaatct ggcaagattg attatgaagt aaatgataaa
     3001 gaattcacca aaactgtgct tgcgaaaaaa gtagataccg gaaaatatcc agaaggaacc
     3061 aagtttactt ttgcggaaat caattacgat aaagatggga atatcaatgg aaaacacaat
     3121 gaagatttga aagaaaaatc tcaaacctta acaccaaaag aagttccaac catactaagt
     3181 acgccgaaac aaccggaaac accaactgtt ccaagtggct ctcaagaatc tagtcccaca
     3241 gtgaagacct tccctcaaac cggggagaaa aattccaatg ttttactgtt cattggtttt
     3301 actttgattt ttgcgacggc gggctattat ttctggaatc gccggaacta aggtgatgag
     3361 atgatacaag taaatcctaa gaaccaacgt gcgcgaccgc ctcctaaaaa agtagtcgcg
     3421 ctatttttgt atccaaaact aacaatgaaa agaggaaaag aagatggaat tgaaatttgt
     3481 cgtgccagat atggctgaaa cctttggaaa gttaagttat gccggtgaag gagaaattat
     3541 aacagaagga tatggacgga atactacggt gattggtcgc agttatcatt tgtattccag
     3601 taagcaacgg gccgatgata ttgaggtggt agtagctgcg gaagccggtg aaaaggattt
     3661 tgatcaagac caaccgctaa aagccgtgaa tccccatttg gttgccaaag gctatgagat
     3721 tgagaatcgt gggtttactg attacgtgtt gtatgttgat gatttagtga aagcatagga
     3781 ggaaaagaag atgagattaa cagaaggtat tgtcgtagat tcaggtttaa catttgggaa
     3841 gttgcgtttt tccgcattac gccgagaagt acggaagcaa aatgaggatg gaacaattgg
     3901 taatgaggta aaagaacgaa cctataattt aaaatcctct gcacaagggc gaatgattca
     3961 agttagtatc ccagctaatg tacccttacg cgagtttgct tatgatgcag aggtagagtt
     4021 ggtcaatcca atcgtggata ccgttgccaa ttatgttttt cgagaaggaa ctaccgttaa
     4081 ttggttcatt aaggcggatg atttagtctt gaagcggcag ccgaatcaag gaaatcctac
     4141 gaaccaaaat gaaagaaaga aataggtgaa gattatggaa attaatgttg aacatatttt
     4201 agattgtctc gatcaatatg gaaaaggcga gctgactgag gaacaactcg ttaaagcatt
     4261 aacctctgat gaaaaaatgt ttctgattat acatcaaggt ttacttggag aaaatagcga
     4321 cagtgaagaa gactctgatg tactagactg gttaggagaa gaagagtctt tctttatagt
     4381 tgtcgaagta aatgaaaact tatgtcggca ggcagaatcc attttggaag aaattggtgt
     4441 ggagatgccg gatgctattg aaggcttttt aaatcaattg gttgaaacga aacaactccc
     4501 ctcctcgtag cagtaaatga ctagcataac tttttgaaat tgcctaatga aatcctattg
     4561 ggctttttcg attggaggtg gaaaccatca aaatgtacaa aggacatcgc atacgcgcag
     4621 gagatcagca cttggtttat cactttgttc ttggctggct actcgctctg ttcatcggtt
     4681 ggatgagcgt cttttatttt caagagttta gacaatttga tatttctaag ctatcacttt
     4741 ctactattga aatcgtttgg tctataaaag atttagtatg tctgcttgga agtctcgctt
     4801 tttcaggagc tatgatattg ctttatattc acttttttct tgatcattgg cgaagcttgt
     4861 ggcatcgaca aaagctagct cggatgattc tagagaacca ttggtatgaa gtgaaacaaa
     4921 ctcaaagtga aggctttttc aaagatttga atagtagccg aaccagagag actatcagtt
     4981 acttccccaa aatctgttat cgaatgaaag atggattact gtctattcgc gttcaaattt
     5041 cacttgggaa ataccaagat cagcttttaa aattggaaaa gaagttagaa agcggactgt
     5101 attgtgagtt agtagaaaag gaactcaaag actcctatgt ggagtatact ttactgtatg
     5161 atatgatcgc caatcgaatt gggatagacg aagtagtggc agaaaatggg actctgcgat
     5221 tgatgaaaaa tcaagtatgg gcttatgatt ctttacccca tatgttaatc gctggtggca
     5281 cgggtggagg gaagacctat ttcctcctca ccattatcga agcactattg aagtcagatg
     5341 cagaattgtt tatcctcgat cccaaaaatg cagatttagc tgatttaggt acggtgatgc
     5401 ctcatgttta ttcacaaaag gaagaaattt ctgcttgtgt ggaagatttc tatgaacgta
     5461 tgatggctcg tagcaaggca atgaaagaaa tgtctaacta caaaacagga gagaattatg
     5521 cctatcttgg acttccaccc aactttttaa tctttgatga atacgtggct tatatggaga
     5581 tgttaacgac gaaagaaagt gcggtgattt tgaataagct caaacaaatc gtgatgttgg
     5641 gtcgtcaatc tggtttcttt ctgattttgg cttgccaaag gccggatgcg aaatatttag
     5701 gagacggaat ccgcgatcaa ttcaactttc gcgtggcttt gggtcgtatg agtgaactcg
     5761 gatattccat gatgtttggg gaggtcgaaa aaaacttctt tatgaagcac atcaaaggtc
     5821 gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt ttatacgcca cttgtaccaa
     5881 aagggtatga tttcttagat tcaattagta aattagaaaa gatgaatgat tgagtgatct
     5941 tcaatactga ctttatactt caagtaacgt ataatacttt tatatagtag gaagaaaggg
     6001 gataattaat atggaaagta atgattctta tttagagtat gcaaaagcaa ataaggataa
     6061 gtttatttct tatattatca aagggaaatc ccccgaagtt ggacgagacg cagtttttat
     6121 ggcagggagt cctggggctg gaaaatcaga ggttgccatt ggattagctg agaattatga
     6181 taaccatgtg attattgatg cggattactt tcgcacccag tttcctgatt ataatggaaa
     6241 aaactctagt ctctttcaaa aagcatcttc ttggttggta gagcaggcat ttagatatgt
     6301 cttagatcat ggctattctt ttattctgga tgcaactttt gcaatattaa gtgctgaaaa
     6361 aaatatctcg cgggcgttga aaaaacattt tcgagtgacg attttctatg tttatcaaga
     6421 ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt gcagagggac gtcatgtgcc
     6481 gaaaaaggca tttattaacg cttttttcaa atcaagagag aacattgcaa aagtaaagag
     6541 taaacatcca gatgtattgc ttcatatcat aataaaagat tatacgaata atatttccga
     6601 agttcattat gctacggata atctagaatt atttttacca ctagggtata gtaggaaaga
     6661 tttggaggtt caattacatg actgagaaag aacaagtaac gaaaattgta aagaaataca
     6721 ataagagcat tgcggattta tcggaaaatg ctactgcaaa agagttcaaa acggtgatta
     6781 aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt agttggatta aataaaaaat
     6841 agtaggacaa attaataatg tatgagccaa gagcaaaatg ttcttggctt ttttctttgc
     6901 aatgaatgag gtaatgtatg agatttttag atttattcgc cggtattggt ggctttcgtt
     6961 taggtatgga acaggcgagc catcattgta tcggtttttg tgaaattgat aaatttgcta
     7021 gacgtagtta taaagcaatt catgatacaa gtaaggaggt ggaaatgcat gacatcacaa
     7081 gtgtatcaga tgagtttatt caatccctcg gaccagtgga catcctttgc ggcggatttc
     7141 cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt ttccgatact cgaggtactt
     7201 tattctttga aatcgctcgg ttcaccactc ttctccgacc taagctttta ttccttgaga
     7261 acgtccgagg attgctcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgc
     7321 tggatggatt ggggtatgac gtggagtggt aggtgcttaa ctcaaaggcc tacattcccc
     7381 aaagccggga gcggatattc cttatcggac attctcgaga cgcatgtacc gaacaagtat
     7441 ttcctatcat tggaccgtct tcaacatctg atcaaaacat cagaaatttg gtaaatatca
     7501 atccttccaa tcgaggaatg ggtggacaag tctatggttc agatggcgta gcgccaacct
     7561 taacaggtga tgaaggaatc aaaatcgcac tgccagcaag ggatggaatc tctgtagcag
     7621 gactattacc gggaaagttt gaacaaggta atcgagttta tgaagttact ggaaccgccc
     7681 ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat tcgaaaaaat gaaacagaat
     7741 atcaagaggt gaagccagaa gacagtgtga atctggcttt tcctaattcc acaagtcgcc
     7801 gaggtcgtct gggaaaacag agtgttcata ccttactaac aggagaccaa caagcgatcg
     7861 tcacggatca gtatcaaatt cggaagctaa cacctagaga gtgttggcga cttcagggct
     7921 ttcccgattg ggcttttgat cgagattctc aagtcaattc agatagtcag ttgtataagc
     7981 aagccggaaa ctctgtaaca gttccggtca tttttgatat tgccagaaga ttaaaagagt
     8041 tggatgtaca tggtttatga tgagttgatt ggagaaattt attgggtgat tggaaagatt
     8101 cagtcagacc cagaattaga agaacaattg cgacggttaa aatttgatat tcgcaagaat
     8161 ggtgtcaaag tcgctggcga tccatattta atgaatgagg agacggatgc tcgaattgaa
     8221 ataaatcaag taattgcaga atttgagcgg attgcggacc aagcaaaaga accagatatt
     8281 cgtcaatact tgttagaaat gaaagcagag ttggaagtaa atggtattac agatgagtaa
     8341 cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga ggattcgcga agcagaaatc
     8401 ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga ccatgatgtc tcacccccgt
     8461 atctaacagg ggggtacaaa aacacaaaaa ataagtaagc aaccattaag aatgcttgtt
     8521 gtatcaaaga tagtaagtaa tttgtatagg tgttaactca tttgaaaaag ttaacacctt
     8581 gaatttggag gtgagaactt ggcacaacgg aatttagatt atcggctatt aaaagaccga
     8641 cgcaacgaat acggcgtttc acaaaataaa ttggctacgg cttgtggact tagtcggccg
     8701 tacttaaatc agatagaaaa tggtggcgta accgcatcta taaaaaccat gaggaaaatt
     8761 tttgaccaac tggaaagctt taatcccgat ttgcctttga cgttactgtt tgactatgta
     8821 aggattcgct ttcccacaac ggatgcacga aaaattattc aagaaattct ccatttgaaa
     8881 tttgagtata tgctccatga agattatgcc ttttactcct atcaagaaca gtatgtcatg
     8941 ggtgatattg tggtgatgtt gtctcatgaa gaagataaag gtgtgctttt agaattaaag
     9001 gggcgaggtt gccgacaatt tgaaactttt ttactcgctc aaaagcgtag ctggtacgac
     9061 tttttcgagg attgtctaaa ggccggtggc gtgatgaaac gcttggactt ggcaatcaat
     9121 gatcgagtgg ggctattgga tatacctgag ctaacgaaaa aatgtcagaa ggaagaatgt
     9181 atctccttgt ttcgtacctt taaaagttat cgttccgggg aacttttaaa ggctgatgaa
     9241 aaggacggca tgggcaatac cttatatatc ggcagtctca agagtgaggt ttatttctgt
     9301 ttgtatgaaa aagactatga acaatatatc aagttaggga ttccattaga ccaaactgag
     9361 acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg cttttcatgc gattcaagat
     9421 ttgttaaaag gtcgtagcat tgagagcacc acgttttcca ttatcaatcg ttacttgcga
     9481 tttgcggata aagtagaagg taaaaggcga accaactggc ccttgaatga acaatggggg
     9541 cgttttattg gacggaatcg gaaagagatt caattaactt ccgagccaaa accgtatacc
     9601 attgaacgaa ccttgaattg gctaggccga caagtcgccc ctacgtggaa aatggctaag
     9661 gagttggatc gattgaatcg gacaacctat atccaggata tggtacagaa tgcacgctta
     9721 tcagaccgac ataaaaagat tttggagcaa caaagtatgg caattgaaaa tttgattata
     9781 tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt tttggtattt ggtggcagta
     9841 tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc agcagcggat cgagcaatgg
     9901 aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt t
//
LOCUS       DARBDN010000094         9852 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000094 DARBDN010000000
VERSION     DARBDN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.095"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            205..684
                     /locus_tag="SCH06_002307"
     CDS             205..684
                     /locus_tag="SCH06_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078842.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            717..2945
                     /locus_tag="SCH06_002308"
     CDS             717..2945
                     /locus_tag="SCH06_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1078843.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3074..4717
                     /locus_tag="SCH06_002309"
     CDS             3074..4717
                     /locus_tag="SCH06_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEG1078844.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4790..5335)
                     /locus_tag="SCH06_002310"
     CDS             complement(4790..5335)
                     /locus_tag="SCH06_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEG1078845.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5358..5843)
                     /locus_tag="SCH06_002311"
     CDS             complement(5358..5843)
                     /locus_tag="SCH06_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEG1078846.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5833..6645)
                     /locus_tag="SCH06_002312"
     CDS             complement(5833..6645)
                     /locus_tag="SCH06_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HEG1078847.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6784..8316)
                     /locus_tag="SCH06_002313"
     CDS             complement(6784..8316)
                     /locus_tag="SCH06_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEG1078848.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8425..9456)
                     /locus_tag="SCH06_002314"
     CDS             complement(8425..9456)
                     /locus_tag="SCH06_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1078849.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3278 a         1831 c         1896 g         2847 t
ORIGIN      
        1 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
       61 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
      121 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
      181 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
      241 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatat ggatgcaaaa
      301 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
      361 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
      421 attttagatt tagcgatctt agctgcgcaa ggaagtttat acttccaaga tgcttatcgt
      481 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
      541 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
      601 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
      661 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
      721 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
      781 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
      841 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
      901 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
      961 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
     1021 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
     1081 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
     1141 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
     1201 attacccttc tgaaatcgtt cgagcgattg aaaaaggcta tttattagag attcaagagc
     1261 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
     1321 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
     1381 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
     1441 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
     1501 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
     1561 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
     1621 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
     1681 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
     1741 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
     1801 agcatacaaa agaaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
     1861 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
     1921 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
     1981 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
     2041 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
     2101 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
     2161 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
     2221 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
     2281 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
     2341 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
     2401 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
     2461 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
     2521 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
     2581 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
     2641 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
     2701 tgttgcttaa tattagtgac ggtcagccaa aagcattgcc ggattataca ggcaaaaaag
     2761 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
     2821 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
     2881 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
     2941 tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt tcgtttctag
     3001 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
     3061 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
     3121 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
     3181 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
     3241 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
     3301 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
     3361 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
     3421 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
     3481 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
     3541 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
     3601 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
     3661 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
     3721 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
     3781 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
     3841 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
     3901 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaaca
     3961 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
     4021 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
     4081 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
     4141 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
     4201 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
     4261 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
     4321 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
     4381 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
     4441 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
     4501 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
     4561 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
     4621 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
     4681 accttatgaa gctcggttat ataaaacaaa caagtaaaac ttcctcgtta aagttcatta
     4741 gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt caataattcg
     4801 ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa
     4861 gggttttcaa acgaggtctg acaggtactt ggacatgctt gatatgcata ccgattgatg
     4921 tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca ggatcattga
     4981 actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga acaacagaga
     5041 caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct cggttcaaat
     5101 gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct tttaacgtac
     5161 ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct ccaacgactt
     5221 cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc tcagccaata
     5281 tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac ttcattttct
     5341 aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag acttgcagtt
     5401 ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg tatagaagcc
     5461 actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat gatcataact
     5521 aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct gaaagaacca
     5581 gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg cggatatcct
     5641 gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc cgttggacca
     5701 taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc attcgtagcc
     5761 ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag catagcatag
     5821 atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc cagaccagac
     5881 acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa caaatttttt
     5941 actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg ttattgcaga
     6001 agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat gagaaaatac
     6061 ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca tccttgtgcc
     6121 gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga gatggatcat
     6181 ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg ccaaattagg
     6241 cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt
     6301 gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg ggatattttg
     6361 ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca ataacccaat
     6421 tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt taagcaattc
     6481 caaagatata gattccagca taaatcgctc attaatatct agtgccccta tagaagtcaa
     6541 ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt ggattcctcc
     6601 accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat tttcctccat
     6661 gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat atttttatct
     6721 catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc tttccttaaa
     6781 tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca ctttcattgt
     6841 agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc gaggaagttc
     6901 atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta aagcaataat
     6961 cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa aatctaacga
     7021 atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca aatccacttg
     7081 ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc cgctatccca
     7141 ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg
     7201 tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat tcccaactga
     7261 atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc ttgcatcact
     7321 tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt cactttggcc
     7381 atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt
     7441 ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa aagcttctgg
     7501 atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct ctagtgcaat
     7561 tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat
     7621 cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg aatgcactgg
     7681 agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg ttttttgcca
     7741 tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga taccagttgt
     7801 accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt gagaaacaga
     7861 caaagcaggt tgttccatta aataaagaat aggaatctgt tttgattttg ttccatttga
     7921 aatttctctc actcgctttt ttgtctcatc atcaaataaa atgaaagggt cttctaaacg
     7981 atcgataaat acttccattg ttgttgttgg tagatgataa gaagtcatga caggcactgc
     8041 accaaggtaa gacacagaaa cagctagaag gtatgtgtca aaagcggaac tcttataaat
     8101 aataactttg tctccggatt tcactccaag atgagccaat tgataagccc gtttcaacac
     8161 actttcgcag cattttttgt aagttgtttc aagtcctaat tctgggaaag ctgaaagtgg
     8221 ctcatcaaag ataatcgggg tctcggaaaa gttagctgca gcttcttgaa aattcgtaaa
     8281 taagttcaaa ggggaatacg ttatggtctc catcattcac actccattat cttttgttaa
     8341 gtaatataca aattcaagat aatcgtaaca taatccttta tataataaca tagtttattg
     8401 tgaaaaaaag atcatacatt tgttttatat ggaagaaacc cgaacgaatg ccgctaattc
     8461 gtgataagaa aaatcaacca tcttttccca gatatcttga aaagaatggg atgagaggta
     8521 tcgattacca cataaataat ttaccgcgtc agcatcatct aaatatagtt ctgcataata
     8581 acgatatgtt tttctgcata gttctggcga tacgttttta tatactgtaa ttttgctcaa
     8641 aatttggcga atagtccgag gagaaatttg ctgatcatgt gaggaacgaa aaacaaaaga
     8701 attttcgtcc gtattttgtg ctgttaactt aaaatagttc tccagaaatg gcatcgcttc
     8761 ttttggtatt ggtactttat tcagtctgtt ttcttttcta ttcagattaa gaatctgctt
     8821 ggtcaaagat acatctttac gtttaagttc tactacttca tggatcttta atccgcaata
     8881 cagaagaatg gcagtaattg caaggttcct cggtctattc ttttcttcaa agctagcttc
     8941 tctgcttgtt tgaaagcctt caatcgggat aaacaaatgc tcaaaatctt tgaaaagttc
     9001 tgcatcgata tatcgcggag ctgctttggt tgtttccggt aaacttgtac ccaaaagaga
     9061 aatctcttct tcaatcagtc ctttttgata caaaaatcgt aaaaaatgat ttaatgaata
     9121 ttgcttcctt gaaatcccgt aatagctatt ttcaaacaat tgctccgttt cttggttcgc
     9181 tgtagtttgg aacgaacgag tatgtcgata gattttagct aagaaattct gataatcttg
     9241 tttttctaaa tggataatca gctgatcatc cacttcttca gaaaatactt ttctcaaata
     9301 atcagtaaac agatgaaaat cttttgcgta ttcatagcga ctgcctaatg aaagggaaga
     9361 acgattttct tctaaaaact gttgaaagac ggaagggagc aagtgtgtac gttgctttaa
     9421 cttttcttgc agttgttttc tagttttgct gtccattaca aattccctcc aatagtgttc
     9481 attttctata ttttaccgca tttcatcaaa tgaagataga cagtttgtct tgatcttagg
     9541 aagcaaattt ttaactaagt actagctaaa agatatgaag taagaagata catttttagt
     9601 tattttatta gtgcagtcat tcttttgatc ttttaattga tttatcctct ttttagctat
     9661 gtggttactt catgagcaat gaaatggatt tggttcgttc taatggcagg aggctctttc
     9721 ttttatttcc gaaaaattag aaaacatttt ttcagaatcg attggctctc catttattca
     9781 ataatggttt gtctaacgat attgttggga taattcttaa agaagtatta gaaatagttg
     9841 gtacttcatt ac
//
LOCUS       DARBDN010000095         9361 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000095 DARBDN010000000
VERSION     DARBDN010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.096"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(92..760)
                     /locus_tag="SCH06_002315"
     CDS             complement(92..760)
                     /locus_tag="SCH06_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1078850.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            894..1181
                     /locus_tag="SCH06_002316"
     CDS             894..1181
                     /locus_tag="SCH06_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078851.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1597..3135
                     /locus_tag="SCH06_002317"
     CDS             1597..3135
                     /locus_tag="SCH06_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEG1078852.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3132..4097
                     /locus_tag="SCH06_002318"
     CDS             3132..4097
                     /locus_tag="SCH06_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078853.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4084..5406
                     /locus_tag="SCH06_002319"
     CDS             4084..5406
                     /locus_tag="SCH06_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEG1078854.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5469..5573
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5647..6390
                     /locus_tag="SCH06_002320"
     CDS             5647..6390
                     /locus_tag="SCH06_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1078855.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6405..7397
                     /locus_tag="SCH06_002321"
     CDS             6405..7397
                     /locus_tag="SCH06_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1078856.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7409..8146
                     /locus_tag="SCH06_002322"
     CDS             7409..8146
                     /locus_tag="SCH06_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078857.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8136..8858
                     /locus_tag="SCH06_002323"
     CDS             8136..8858
                     /locus_tag="SCH06_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEG1078858.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8942..>9361)
                     /locus_tag="SCH06_002324"
     CDS             complement(8942..>9361)
                     /locus_tag="SCH06_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HEG1078859.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3068 a         1607 c         1972 g         2714 t
ORIGIN      
        1 tttttttata aagaagattt tactgaataa tatcatttta gtttacataa tgatatttct
       61 gtaaattaaa taaagtagtg aaaaataaga atcagtgctc taactgttca agaggatcaa
      121 gtggttcaaa tgtttctgta gtctgttttg cttccaattg gggcaaaaca gatccaattt
      181 ccagatactt cactttattc aatgtataag atagaataga acagctaagt aatgtataca
      241 gaaaatgtgt gagatccaaa taaagcaagg agacaactaa aataccaaaa gtaatcaaga
      301 aaagactttt gccaatctta atatgaaaat atttttcaat ggcttgataa atgatatctg
      361 ttccgcctgt gcttccgccg aatcgaaaga cgagaccgca accaatgcca gaaagaatac
      421 ctgtcatcaa actattgatc agtagactat ctacagcaaa atgtatatga aggctctccc
      481 ataaatgtaa aaagaaaact agcgcaaatg ttccgacgat cgtccggaga aaagcgtgtt
      541 ttccaaaaag aaacaatgag ataagcaata aaggtaaatt aaaaagcagt gaagtgacag
      601 aaggagcgaa tccaaaaaga ttatgcaaaa gcaaagcaat accagtaacc ccaccatctg
      661 ccagcttaga tggaatattg attcctgtca cagctaatcc gtagattcct gcgcctaaaa
      721 tgattccgca caattctgta aataaattta attttttcat ttctagcctc ttttcttttg
      781 aaaattttca gcaacttctt tattatactg acttatactc ttacttcaag aggaaaatga
      841 aaaaaaatta tttttggctg tttcttttta tttatcaaat aaggagtgga aaaatgcgag
      901 cagcagactt attgacaatt cttacaaaat cacccaaaaa aacagagtat caaggagttt
      961 ttttggctca agaacaaaaa ctggtgcctg tgacaatggt ccagataaat aaagcaaatc
     1021 aatttatctt tttatttgaa cacggcaaag caccacttgc tatgaaagac atctttcttt
     1081 ttttgatgaa gaaccgtgag aaagctgttt attatcagtc aaaagaagaa ctcattcctc
     1141 tttatggagt gaaagagata gaaaataaag tggtgatata agtaaaaata agaaaacaag
     1201 acgtttatga tgtcaaaaca accatttttt acatttttgg caaaaaagtg tcatgataca
     1261 gtataatatt cgttgaacag gccaataaag gtgttctccc ccacgagatt tctactttat
     1321 tggctgtttc tttttattaa aataaaagtt gtgtgtgtaa aaaagatata gctgattcca
     1381 agtgacaatt tcgtatagat ttttatggta ttcgtagtga aaaaacgaga accaaaaagt
     1441 tgatccgact ttgttgcttg gattcttttt ttgtcagcat atttagaggt atttttttct
     1501 tttttttgtt cgtgctgtaa ggttaaggca agacaagtta gttgggaaaa aggaaagaaa
     1561 tgtttatact taaagaataa cagaaaggaa ggtcgcatga ataattttat acaaacatta
     1621 agtgaaagaa aaggcgagtt gctggaagct gcatttcaac atctgtccat ttctctcatt
     1681 tctttgctga ttgcagcact gattgctatt cctttagcga tttgggcagc caatcataaa
     1741 aaaatggcag aagtcttatt gcagatcacg ggtgtgctcc aaacgattcc ttcacttgcc
     1801 ttattaggtt tacttatccc atttgtaggg atcggaactg ttccagcatt gattgcactt
     1861 gttatttacg ctttgcttcc gattttccaa aacacgtata ttggtctagc tgaaattgac
     1921 ccgtctattg aagaagcagc ggtagcattt ggtatgtcca gaatgagacg cttgctgaaa
     1981 gtagagcttc ccatcgcatt acctgtcatt atctcaggta tccgaactgc cttagtttta
     2041 atcatcggta cggctacttt ggcagcattg atcggagcag gtggattagg gacatttatt
     2101 ttgttaggta ttgaccgaaa tacacctgtt ttgacattga ttggtgcgat cagttctgcc
     2161 ttgcttgcaa ttatattcag cggactgatt cgctggttgc agcataagaa acctcgatat
     2221 tccatcatta ctttagcagc agtggtgtgt ttatttggcg gcgtttcttt atatcagtct
     2281 gccttgttta aaaatgaaac catcacgatt gctggaaaat taggagcgga acctgaaatc
     2341 ctgatccaaa tgtataaaga attgattgaa gacaacacaa aaacagaagt tgaattaaaa
     2401 ccgaattttg gcaagacgag ttttttgttc aatgcactgg atcaaggtca aatcgatatc
     2461 tatcctgagt tcacaggtac tgtcctagaa agcttggtga aggtacctga agcaatgaaa
     2521 agtgctgatt tgacaaaaga aaaaacatat gacgaagcag aagaattatt gaataagcaa
     2581 ttcgatatga cattattaaa accaatggct taccaaaata cgtatgcctt ggcagtcaag
     2641 agatcttttg cgaacgaaca tcaacttaaa aagatttccg atttggcagc tatctctgat
     2701 cagatcaaag cgggattcac actggaattt attgatcgtt cagatggata taaaggaatc
     2761 caagaagcat atggcttgaa tttttcaagt gtacaaagca tggagccaag tttgcgttac
     2821 caagcaatca ataatggaga tgtcaatatt gtggatgcct attccacaga tagccagctc
     2881 aaggagtacg atctagtgac tctagaagat gatcgagggt tattcccagc ttatcaaggc
     2941 gcaccgctga tgaaaaaaga ttttgctaaa gaacatcctg aaatcgttaa agcactgaat
     3001 aaattaagcg gaaaaataac ggaggatcaa atgattgata tgaattacca agtcaatgtc
     3061 gaaaagaaaa agccgacaga agtagcacga atcttcctga aaaatgaagg attagtaaag
     3121 gaggaagatc agtgactaaa ttaatcgagt tcaaacatgt gcaaaaaaag tatgatggaa
     3181 agtatgtcat cgatgaccta aatctggcaa tcaaaaaagg agaaatcttt gttttggttg
     3241 gtccttccgg tagtggaaaa acaactactt tgaaaatgat caatggatta tctaaaccat
     3301 cagcaggaga catctacttc aaaggaaaat cgttaaatga atataatctg cagaaaatgc
     3361 ggtggaatat gggatatgtg ctgcagcaaa tcgctttgtt cccgaccatg acagtcaagc
     3421 aaaatattga agtcatccct gaaatgttag gttgggaaaa gcagaaaaga gcagaccgtg
     3481 tagatgaact tcttcaaaaa gttggcttat ctcctgatat ttatcgagat cgtatgccta
     3541 gagagttgtc tggaggagaa cagcaacgga tcgggatcat ccgagctatt gctgcaagcc
     3601 cagatgtgat tttgatggac gagccattta gcgcattaga tccgatttca agaaactcat
     3661 tacaagaatt ggttttgtcc ttacacgaag aattgggcac gaccatcgtt ttcgttacgc
     3721 acaatatgga agaagcaatc aagctaggtg atcgtattgc atttatgaag gatggagaaa
     3781 ttatccaatg tgacacacca gagcagttat tgatgaatcc taaaaacgac tacgttcggc
     3841 atttctttga tgaaccgaaa cagacgaaag agtggcgagt agaagattta gtcgtcaatg
     3901 gatatttctt aaatgaaata ccagaaaatg ctcgtcaaca agtttgcttt gatacgccta
     3961 tgaaagaagt atattcgctt ctttcggtgt atccaagcat tgtgatagta gaaaagcaaa
     4021 gaagtattgg gtcgctgaca agtaaagaaa tctttgcttt tttaagtcga gaggaggaag
     4081 gaaatgaaaa catatgatgc aatcatcatc ggttcaggtg tgagcggctt aagtgctgct
     4141 tatggattga aagaagcagg taaaacagta ctagtggtcg aagaagatct atggggcggg
     4201 acttgtccta accgtggatg tgatcctaaa aaagtcttgt taagtgcagt agaggcacgt
     4261 aatcgggtaa aacaattgag tggaaaaggt tttaacgaga tcccaactgc caactgggaa
     4321 gaacttcaaa aattcaaacg aacatttacg gatccagtcc cagaaagccg aaaaaaacaa
     4381 ttagcagaag ctgaaatcga tcatctttca ggaaccgctc gttttttgga tgattcatct
     4441 attgaagtca acgaagaagt cttccatgcg gattacttag ttttggcaac cgggcaaaga
     4501 cctacgatct taccagtgga gggaaaggaa tacttgaaaa ctagtgcaga ctttttatca
     4561 ttgcctgtac tgcctaaaga aatcattttt atcggtggtg gttatattgc ttttgagcta
     4621 gctacgattg ccaatgctgc agggagcaaa gtaaccattg tccatcataa tcaacggcca
     4681 ttaaaagaat ttgaggcgtc tttggtagag gaagccgtcc atcaaatgga agcatctggc
     4741 attcagtttg cttttggtgt tgaaacccaa aagatcattt cagaaggtac tcgctatcgt
     4801 ttagtcggaa aagagacgga attagtagca gatatgattt tttgtgcgac tgggagacag
     4861 ccgaatacag aatctttagc acttgagcaa gcgaatatcg tctttgataa acacggaatt
     4921 gcagtcaatg attatctgca aacgagcaat ccaaaaattt ttgcgtgtgg agatattgtt
     4981 tcaaggaaaa ccccaaaatt gacaccagtc gccacttttg aaggaaatta tgtagctaag
     5041 cggataacgg atgcaacaag cgaacctatc aaatatccga ttatacctac gatcgtctac
     5101 gccagtccta aacttgctga agtaggagtt acaaaaagtc acgcctcttc gtcagatcaa
     5161 gtggtagaga tggatcttac cagttggttc acctatcatc gtgtcaatga accagttgct
     5221 aaggctgaat tgacctttga ccagcaaaat tatttgattg gtgctgcagt gattagcgag
     5281 caagcagacg aattgatcga tgatttgaca ctcgtcatca atcaaaaatt gactaaaaaa
     5341 gagttggata gctatatcat ggggtatccg acattggcaa gtgatctctc ctatttattg
     5401 aaataatcag catgataact aaagcgcttg ttgctttttc cttcttgtgc tacactttaa
     5461 aaaatgaata cctgtttctg gggatgtcgt agacgacatg agagtaagtt gtgaacttag
     5521 acccattgaa cctgtcagtt aatactggtg aagggagaaa catagcagac gcttgaagcg
     5581 ggttactatg tcgtgcccat ttcaagcgtt ttttgttatt catattagaa gaaaggaggt
     5641 aacaaaatga agaaaaatct ttatccagca gtcagtatgg cattcatttt aattatttgg
     5701 cagattgttg tcatagtttg gaaaatacct gcctttattt tacccggacc tgctgctgta
     5761 ttttctgcat tagcggcaga tgcacaagta ttactttccc attctgtcac gacattaaat
     5821 gaagcagtgc ttggtttggt aatagctagc gttctttctt ttattactgc cttggcaatg
     5881 gattattgga agtttttaga aatgtctttt tatccgttac tagtgatttc acaaatgttg
     5941 ccaatcatgg tgttagggcc attacttacc ctatggtttg gtttcggtat gcttccaaaa
     6001 gtgatccttg ttgtcttgat aagctatttt ccgatcgtag tttctttttc ggatacattg
     6061 aggaaagtat caaaagagca aatcatcttt ttgaaaacga tgggggcaga tacagggaag
     6121 atttatcgaa tatataaaat accagcgggt ttatccggct tcttttccgg tttaaaagtg
     6181 gctgctactt attgtgtcag cggagcagtc gttggagaat ggctaagcgc tcaagcaggc
     6241 ttagggtatt acatgatacg cgtaaaaaac agctaccaga tcgataaagt ttttgctgcg
     6301 atcatttgtg tcattctatt gagtttattg ctgaatggcg cttgttcatt attgaaaaaa
     6361 gggtattatc gtatgcttta tattttttaa gagaagggga tcaaatgaaa aaattatggc
     6421 ttttattacc gctactgttg cttttatccg cttgtggcac tgcaaaagaa acaagtagca
     6481 aacaagaaat aaaggatttg aaaaaagtga cacttgtttt ggattatgta ccgaatacta
     6541 atcatactgg catctaccta gcaaaagaaa aaggctatta taaagaggct ggtttaaatg
     6601 tccaaatcat cgaaccagga gataattcga caagtattgg tctagtaggt gcggacaaag
     6661 cacaatttgg tgtaagttat caagaagatg tcacttatgc tcacgcagat ggacagaata
     6721 taccagtcaa agcaattgct acagtgatca aacataatac ttctggattc gccaccctat
     6781 cagacagtaa catccattca ccaaaagatt ttgaaggaaa aacatatgca ggttggcaaa
     6841 gtccaagtga agaagctgtc ttaaaagctg tgatggaaaa agacggcggg gacttttcaa
     6901 aactgacaat ggtaggaagc aatggagaag ggccagaaag cttaggaaaa tcctcagata
     6961 tccaatggta ctttgaaggt tgggatatga tcaaagcaaa agaagcgggt attgaactaa
     7021 actatatccc attgaaagaa ttagatgaac ggttagatta ctatactccg gtaattatta
     7081 cgaatgatca actgatcaaa agtgatccag aattggtaca gtcttttatg gatgccacga
     7141 aaaaaggcta tcaggaagct attaaggatc caaatgacag tgctaaactg ttgcaaaaat
     7201 atgcaaaaga aaatgatcgg acgtttttag aagaatcaca agcattcttg tcaaaaaatt
     7261 atacggatga tcctgagaat tggggattga tggaagaaaa agtttggcgc aattatacag
     7321 cttttatgca ggaaaacgga ttgatcaagc aagatgtacc ttcgcaagaa ctattcacta
     7381 atcagtttat aaaataggag tgatagatat gtcaatccaa atcagccact tgaatgtagt
     7441 cattgaaaac ctgaaaatat tagaagacat ccatttcact atccctaaag atacctttac
     7501 atcgattgtc gcgccaagcg gagccggtaa gtcaacattg ctgaaaactt taacaggagt
     7561 ccagcctatg acttctggaa cgatcaaagt agacgatcaa aaagtaactg gtctccatac
     7621 agcatttagt tatatgccgc aagaagatat gttacttcct tggctgagcg tctatcaaaa
     7681 cgttacgtta tatcaaaaaa tcaatcatct aacaatcaat gaagaacaag taagggatta
     7741 tctggatatc tttgggttaa acggctatga acattttttg ccggaacaat tatctggcgg
     7801 gatgaagcag cgaacggcct tgttacgaac aatcatgaat ccttcttctt acttgcttct
     7861 tgatgaacca tttggagcgt tagatgctat gaccagaggg cagatgcaag actggatgtt
     7921 gaagctgcct aaaaaagcaa agcggactac tttacttgtg acgcatgata tcgaagaagc
     7981 aatttattta tcagacagga ttcttgtgct ttccgcccgt ccggcacatg tgattgctga
     8041 gattcaagtg cctgaaaaac gacggtcacg tgaatggcta ctgcagcaat cagagttgaa
     8101 gcaaacgatt tatcagttat tggcaggtga attagatgtt aagtgatgct cattgtcatt
     8161 tagatgggag tcagagttta gcactccttc agcaggaaca cacgattttg acgatcatca
     8221 attgtgattc gccagaagaa tggaaggaaa acagacagct tgcagcaagt aagactcaag
     8281 ccttaagtta cggtatccat ccttggaaag cagatagcta tacgtttgaa caagttgagc
     8341 cttttttgaa aaaagcaagg atcatcggtg aaatagggtt agataatatt tggacgaatg
     8401 taccgatgac tacacaaaaa aaagtatttg agcgacagct tgcttttgca gccataaatg
     8461 agaaacctgt tgtactgcac acaaaaggat gcgaaaaaga gatcttaaat tatatccaag
     8521 cttaccctaa tcactatttg atccattggt attcttcttt ggactatcaa caagactata
     8581 ttgatttagg ctgttatttc agcattggtc ttgatttgaa aaagaatcca gcagtctggc
     8641 aactagctaa agcagtccca atcgaccact tacttattga aacggatgga ctacatgcag
     8701 cagagtgggc tttagggggg attttttcag aaaaagatta tgtctcactg cttgaagaac
     8761 agttaaagac aatcgctgag atcaaagagc tatcagttga agaagttaaa aaaaatactt
     8821 atcaaaactt ggaacgtttc attagattag gtaaataaaa aagagatgtg acacaactag
     8881 tgtcgcacct ctttttggct ttctttgtat aaaagtaaac tgtttgatta ataaatgaat
     8941 cttagtacca accgtttgct tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg
     9001 aagtaacata ttgttctgct actctttctt ggtttgcagc agagtagtca ccatttaagt
     9061 aagaagaatc taattggtaa cgtccgatgt aacgtccgtt cgttgctgtg taagaaccgc
     9121 ttgattcttt ttgtgcgatc cattcttttg cagagcttgt gcttgctgga gtagcagcag
     9181 tttctgttac agcaggagca ggttgtgttt cagcaacagg cgctgcttgt ttttccgttt
     9241 gaaccgtttc ttgtacaaca ggttgttcag cttggactgg tgcttcttga acggctgctt
     9301 gaggttcagc agctgcttgt gcagagcctt ctgttgggat tgttaattgt tgtcctgagt
     9361 a
//
LOCUS       DARBDN010000096         9357 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000096 DARBDN010000000
VERSION     DARBDN010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.097"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="SCH06_002325"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="SCH06_002325"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEG1078860.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="SCH06_002326"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="SCH06_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEG1078861.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="SCH06_002327"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="SCH06_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEG1078862.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="SCH06_002328"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="SCH06_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEG1078863.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="SCH06_002329"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="SCH06_002329"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEG1078864.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="SCH06_002330"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="SCH06_002330"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEG1078865.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="SCH06_002331"
     CDS             complement(8053..8523)
                     /locus_tag="SCH06_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HEG1078866.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="SCH06_002332"
     CDS             complement(8569..8994)
                     /locus_tag="SCH06_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEG1078867.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="SCH06_002333"
     CDS             complement(9061..9330)
                     /locus_tag="SCH06_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEG1078868.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
BASE COUNT         2355 a         2095 c         1621 g         3286 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gctttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc ccctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatggaat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttt
//
LOCUS       DARBDN010000097         9329 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000097 DARBDN010000000
VERSION     DARBDN010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.098"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..365)
                     /locus_tag="SCH06_002334"
     CDS             complement(<1..365)
                     /locus_tag="SCH06_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEG1078869.1"
                     /translation="MRNKKVIVRILIVSFLLFGCFKLIKTNEESNGKLINSNLEEVLE
                     LQKTNQSFFVYLARNDCKKCQEVESFLERYDKKFSRNVYRIETRKEPRQEELQTFLQR
                     YHVKSVPSFLVIHDRNVKK"
     gene            complement(355..2529)
                     /locus_tag="SCH06_002335"
     CDS             complement(355..2529)
                     /locus_tag="SCH06_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 family protein"
                     /protein_id="HEG1078870.1"
                     /translation="MMNAPKRPTHFEQMFSVDRKRKQEKETPKSRFQQLYFIVTLLGV
                     CLYPFFIVGSIPLAIVFMIDKKETRAHIYDFEYESFLKRRSSLFFIFALGFTLLNLFC
                     FIFVLPRGYLSCYLLFPLNLFSHALQFNGQTIFALLLGGTGAGSCLIAYASFIEKRKV
                     VSKKERQTALLNSKEYKERRKNKFQESQKYTAEYQQAYQVAIVIKDVALRNKQLASLA
                     KVILLGTDEYGLPYVMNFSELNQHVIIPATTGSGKTTVIQLLAEHACKFRIPVILVDG
                     KGAGETLQALKEVAEAYNRPIEVFVDGGDLRYNPVKNGNDIAIRDKLTNLAETESVYY
                     STAAKALLQVTIQLLDEFQKSHKIERNLVWLQHYLLPRNVLHLFADRIQLKNPDLFKE
                     KVVVEKKKTTKKKTKKNEAMDKTERDFADVEQLSEERIVEHDRKTVDLETYYLLLKEN
                     ISLMTEIEQTLFKRLFVRYEHKKNPFYLYATSENLQTNINMLLDSELGELFDTSGGKR
                     ELDIQEVVKEGKIVYISLNGLIYSEFIRTLAQMLVGDINFFASEVYKQAGETANRSKV
                     LVIFDEPASYLNDNLIDLVNKGRGAGVHAAYAPQTLADIDRIDPVLRKQLIGNVNTFF
                     IGKTNDPTEIDYWADLMGTEEDIELTEMTTQEAGYSDMGKVDWTGERGTKRDVDRFKF
                     NPNRIRALRTGEFVVYRTAEDVQEPPRVVYIRKPNLEKQYAK"
     gene            complement(2545..4887)
                     /locus_tag="SCH06_002336"
     CDS             complement(2545..4887)
                     /locus_tag="SCH06_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078871.1"
                     /translation="MRKKSLKWWTLLLLGGLFFCLQGATVSADQMNDGAGVTETDRSE
                     GENANDKVEVKEVTTDVDQLYKNYKKNSFELMTNDYESMNLKKKLSYNVAGVMKNFVW
                     SGVKMLGEFNASMVEFLFELDIISAIREPIQNLTQKIADNMLSIAGTIGISFSAIMMA
                     IKYAGEARMKQALRVFLMTILIFTGLSVLKDSGTNKNLFDVLFSLDSTVETAFVKVNP
                     VLTPEEETNYETKETEEVTADKKVETAGKLMAARVFYSNVYEPYLLLNYGTTNVDTIR
                     EKKVKYAGKEYDRINLLLDNDLGTKIGEKIHDKVTEYEADTLKNKNIQYYNSWKNTAF
                     ALFYFVVNLIQTVVYFVLSMFRLIIGTMQLLLVPMLPFLLFLGLFLVTMNVFGNYAKV
                     FGILTFLKGMTGFACILFSSFLSYGFQLSSTQDDPWEKILLIIVYLFAPLGIYLFRGF
                     LGSLFTGRMGVRGALAFAGNPFGAEAKLRREAKQRLKERKEARKAQKQKEKENARKRQ
                     ERQRKRGGGSDVRMPQTAKQATRSAFRRESAQQPRHKAPNRMERMAQKARDLHDQAKQ
                     AEEQSQERMQRTAMEKQARKTADLLQRELQGNPSLRERSRKGASRSPYRNQGSAMVVS
                     LANPKQKHKSYGQKHTPRTELNDRKRRQGQTSRRRKEALTPVTKTSSMKTRTVAGQKH
                     AVQKPLRKGNVPRATGSTTPKSVRRPEGVREHMSAVNRVTAQTKAPSTVSKAYSTMKQ
                     TKSPKQAPKTRSEFRATQAKMKRKREKQPIYRREMKQRKR"
     gene            complement(4909..7452)
                     /locus_tag="SCH06_002337"
     CDS             complement(4909..7452)
                     /locus_tag="SCH06_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1078872.1"
                     /translation="MAFLFLLVVFIIGIWQFKKKKTKLPRLEFPIDAIIRNFVLTKND
                     DVWVGYQLSSQVFPLNDIDFFKNYLQDGEGILGHDEYDYHFINIPRQFNLDTHIEETI
                     RDLVKGECADLGKVYFEQAGKILKDEVQLNEYRTYLFVRFTTEMKVSDPIEYFQLLKH
                     VFKKFIYRITGQRVPISSVLPTYETLEKELYTELSNYKPIERLSAQEIGQIYYYFFHR
                     SEEKLPERQLTPMEICEGVISNEAGYIAIEQLNQTHYSTFLSQTDAPLAMYGSSFIQN
                     LQDSLSFPIDTHIRLRFEHSKSDERKINKMAGRIYEQEKEYETVDGILDSDDVLNFGT
                     ERLMDVKDKLKRKEKRLCYSTVTLVVSASSKEELEERVKDIEFAIESTDFKFYRSVAD
                     QLTLFNQCLIGSTQRFRSYEQVATTGFVADYGLDLKKEVGNKKGFPLGRIVIAKKFKS
                     AKEALALSSKLVWYYPNLTKKSIEGAEHTNGNTLIIGPPGKGKSVLVKYIFLWLMFLG
                     QKILYIDPKNETQKFFLKALEKFGHIPEFVAMYERINFISLSSDESCRGMLDPLLFLP
                     KEEAIQTAKNVLGMLGEVDTNRETASHKKTVIQDAIDVVYTMPGKHSLSQVIEEIRKS
                     DKELAKLILGHSVGLGKILIGNEHSTPIRFDSQINVLGTQGIRIPTQKEIDSGRLNSE
                     QLAGMAIMEVIMKFTYIFSTNKEEDAAIIYDEAKGYEDTAQGSYLIDDSLRKGRANNT
                     DIYLVVQAFKDYDQEDKKELISYKFAFRPKQKEAREKLLSFFDMEVNSANLEMMEQLQ
                     TGTCLFQDHLGRNQPIAIDVLFDSWLLAVSSTENQDEKIQAMLENEKQR"
     gene            complement(7462..7860)
                     /locus_tag="SCH06_002338"
     CDS             complement(7462..7860)
                     /locus_tag="SCH06_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1078873.1"
                     /translation="MEYNYTKEFKHPHKIYGIKGQKIPWISNGIRMEQLVIGGVFLFI
                     LLILFLIAYVNQISFLQTLFRKSWLIMIFGIGVLVWTLFSMKWDNKHFFEYLIGRTSY
                     YQKRKQRFEHEMYVPFFHEKVTYSLHKWKE"
     gene            complement(7941..8225)
                     /locus_tag="SCH06_002339"
     CDS             complement(7941..8225)
                     /locus_tag="SCH06_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078874.1"
                     /translation="MKLFDLKSLFDDVSGQVIWLLAIVAIVLMVGAYATQGFARAAFA
                     IIGVFILIMLVLLLSNAVDIGEWLKNIIFIKDSEENVGVTQMIVPWIQLS"
     gene            complement(8249..9247)
                     /locus_tag="SCH06_002340"
     CDS             complement(8249..9247)
                     /locus_tag="SCH06_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1078875.1"
                     /translation="MSNAKFNPQAFQTKPPKQQKEKKQKKRFLFQKKKTEPSDRMIQF
                     SQKSAMSVFSGAFFCLFLLMGVVLLLNFGRVDTLTRLAVKKQVNPETLLTEVNQTLSS
                     TEQLKYEGQHFIERLFTYSPEKRNEWEASVNHYLAQGLEASDLGFVTTATNRVAKDVR
                     FIKLEEIDLTQAMYRLFYEVTFTEGEHWKSSQLSFPVSYQNNVLKVLDGVQFLNLSES
                     KNTNSVNYQENRFYSSGQAVTESEEIKLEAFVKRFFELYVKNDEKLALISNEKGLEGG
                     ELINVQLDHAVKNKEGNYFLQGKYRFYFEKGNEFQSNFSMEVKTSGDSYFVTTLNE"
BASE COUNT         2652 a         1999 c         1461 g         3217 t
ORIGIN      
        1 atttttttga cgtttctatc atgaatcacg agaaaacttg ggacactttt aacatggtaa
       61 cgttgtaaaa aagtttgaag ttcttcttgt cttggttctt ttcttgtttc aattcgatat
      121 acattcctag agaatttttt gtcgtatctt tccaagaaag attcaacttc ttggcatttt
      181 ttacaatcat ttcttgctag atacacaaaa aatgattgat tcgttttttg aagttctagt
      241 acttcttcta aattactatt gattagtttt ccatttgatt cttcgttagt ttttatcagt
      301 ttaaaacaac caaataagag gaaactaaca ataagtatcc taacaataac tttcttattt
      361 cgcatattgt ttctccaaat ttggtttccg aatatagacg actcgcggtg gttcctggac
      421 gtcttcagct gttcgataca ccacaaattc gcctgttctc aatgctcgaa tgcgattcgg
      481 attgaattta aagcggtcta cgtctcgttt cgtgcctctt tctcctgtcc aatcaacctt
      541 tcccatatca gaataacctg cttcttgtgt cgtcatttcc gttaattcaa tgtcttcttc
      601 tgtccccatt aaatctgccc aataatcaat ttctgtcggg tcatttgtct tcccaataaa
      661 gaacgtattc acattcccaa tcaactgttt tcgaaggaca ggatcaattc tatcaatgtc
      721 cgcaagcgtt tgaggggcat acgccgcatg caccccagcg cctcgtccct tattgactaa
      781 gtctataagg ttatcattta gataagaagc tggttcgtca aatattacta ggactttcga
      841 gcgattggct gtttctcctg cttgtttata cacttctgac gcaaagaaat taatatctcc
      901 cacaagcatt tgagccaatg tccgaataaa ctcactataa atcaatccgt ttaacgagat
      961 ataaacaatc tttccttctt taacaacttc ttgaatatct aattctcttt ttcctccaga
     1021 agtatcaaag agttcaccaa gctcactatc caataacata ttgatattgg tctgtaaatt
     1081 ctcagaagtc gcatacaaat aaaacgggtt cttcttatgt tcgtaacgaa caaacaaccg
     1141 tttaaacaac gtttgctcga tttctgtcat gagagaaatg ttttctttta ataatagata
     1201 atacgtttct aagtcaacgg ttttacgatc atgttcaacg attcgctctt cacttaactg
     1261 ttccacatcg gcaaaatcac gttctgtttt gtccatcgct tcattctttt tcgttttttt
     1321 cttcgtggtt ttcttctttt ctacgaccac tttttcttta aataaatctg gatttttcaa
     1381 ctgaatacga tccgcaaaca aatgtaagac gtttcgtggc aataaataat gttgtaacca
     1441 aactagattt ctttcaattt tatggctctt ttggaactcg tctaaaagct gaatcgttac
     1501 ctgtaataac gctttggctg ctgtcgaata atacacgctt tctgtttctg ctagattggt
     1561 taatttatct cgaatggcaa tatcattgcc attttttaca ggattataac gcaaatcgcc
     1621 accgtccaca aagacttcaa tcgggcgatt gtatgcctct gccacttctt ttaacgcttg
     1681 taaagtctct cctgctcctt tcccatcgac taagataacg gggatacgaa acttacacgc
     1741 atgttctgct agtaattgga tcaccgtcgt ttttcctgaa cctgtagtcg ctggaataat
     1801 cacatgttgg ttcaattcac taaagttcat cacataaggg agcccatact catctgttcc
     1861 taatagaatc actttggcta atgaagccag ttgtttattc cgcaaagcaa cgtcttttat
     1921 gacaattgct acctggtacg cttgctgata ctctgctgta tatttttggg actcctgaaa
     1981 tttattcttc cgacgttcct tgtattcttt actatttagc aaagctgttt gccgttcttt
     2041 ctttgaaaca acttttcttt tttcaataaa agacgcatac gcaatcaaac aacttcctgc
     2101 acctgtccca cctaaaagga gggcaaaaat cgtttgtcca ttaaactgca acgcatgaga
     2161 aaacaagttt aatggaaata ataagtaaca cgacaaatac cctctaggaa gaacaaaaat
     2221 aaaacaaaat agatttaata gcgtaaaacc taacgcaaaa ataaaaaaaa gagagcttct
     2281 tcgttttaag aagctctcat actcaaagtc ataaatatgt gcacgtgtct cttttttatc
     2341 tatcataaag acaatcgcta aaggaatact gcctacaata aaaaatggat atagacaaac
     2401 acctaataaa gtgacgataa aataaagttg ttgaaaccga ctttttggcg tttctttttc
     2461 ttgttttctt ttgcgatcga cagaaaacat ttgctcaaaa tgtgtcggtc gttttggtgc
     2521 attcatcata ctatcgattt cctcctatcg ttttcgttgt ttcatttctc ttcgataaat
     2581 cggttgtttt tctcgttttc gtttcatttt tgcttgagtt gctcgaaact cactccgtgt
     2641 cttcggtgct tgttttggtg attttgtttg tttcatggtt gagtatgctt tagatacggt
     2701 tgaaggcgct ttggtttgtg ctgttactcg attgactgct gacatatgtt cccgaacccc
     2761 ctctggacgt cgaacagatt tcggtgtggt agaacctgtt gctcgtggta cattcccttt
     2821 tcttagtggt ttttgtaccg catgtttttg tcctgcaact gtccgggttt tcatcgaact
     2881 tgtttttgtt acgggagtaa gtgcctcctt ccgacgacga cttgtttgtc cctgacgacg
     2941 ttttcgatcg ttcaattctg ttctaggcgt atgcttctgg ccataagact tgtgtttttg
     3001 ctttggattc gctaatgaca ccaccattgc agaaccctga ttgcgatacg gactacgaga
     3061 cgcacctttt ctacttcttt ctcttagact aggattgcct tgcaattctc gttgtaataa
     3121 atcggctgtt tttcttgcct gtttctccat tgctgttcgt tgcatacgtt cttgactttg
     3181 ctcttctgct tgtttcgctt gatcatgcaa gtctcttgct ttttgtgcca tacgttccat
     3241 acgatttggt gctttatgac gaggttgttg tgcggattca cgccgaaaag cacttcgtgt
     3301 ggcttgtttc gccgtttgtg gcatacgaac gtctgagcca cccccacgtt ttcgttgacg
     3361 ttcttgtctc ttccgtgcgt tttctttttc tttttgtttc tgtgcttttc tcgcttcttt
     3421 gcgttctttc aaccgttgtt tggcttccct tctcaatttt gcttctgccc caaatggatt
     3481 tcccgcaaaa gctaacgctc ctcgaacacc cattcttcca gtaaatagac tgcctaaaaa
     3541 gcctcggaac aaataaattc ccaacggcgc aaacaaataa acaatgatca agagaatttt
     3601 ttcccatgga tcgtcttgtg tactacttaa ttggaacccg taactaagaa aagaagaaaa
     3661 aaggatacat gcaaaacctg tcattccttt taaaaacgtc aaaataccaa aaactttggc
     3721 atagttacca aacacattca ttgtgacaag aaacaatcct aaaaaaagta agaacggcaa
     3781 catcggtact aacaatagtt gcatagttcc aataatcaat cgaaacatac ttaagacaaa
     3841 ataaacaacg gtttgaatca gattcacgac aaaataaaac aaggcaaatg ctgtattttt
     3901 ccaactattg taatattgta tgttcttgtt tttcagtgta tctgcttcat actctgtgac
     3961 tttgtcatga attttctccc ctatttttgt acctaaatca ttgtccaata aaagattgat
     4021 tcgatcatat tcttttccag catatttgac tttcttctca cgaattgtgt ctacattggt
     4081 tgtgccataa tttaacaaca gatatggttc ataaacatta ctataaaaga cccgagccgc
     4141 catcaatttg cctgccgttt ccactttttt atccgctgtt acctcttctg tttcttttgt
     4201 ttcataattt gtttcttctt caggtgttaa cactggattg accttcacga acgccgtttc
     4261 cactgtagaa tctaaagaaa aaagaacatc aaaaagattc ttatttgtcc cagaatcttt
     4321 taatacgctt aacccagtaa aaataaggat cgtcataaga aagacacgga gtgcttgttt
     4381 cattcgagcc tctccagcat atttgattgc catcataatt gccgaaaaac tgattccaat
     4441 agttcctgca atacttaaca tattgtccgc aattttttgt gttaagtttt gaatgggttc
     4501 tcgaatggcg gaaataatat ctaattcaaa gagaaattca accattgaag cattgaattc
     4561 tcctaacatt tttacgccac tccaaacaaa atttttcatc actcctgcaa cattgtacga
     4621 tagctttttt ttaaggttca ttgactcata gtcattggtc atcaattcaa acgaattctt
     4681 tttgtaattt ttatacaatt gatccacatc agtcgttact tcttttactt ctactttatc
     4741 gttggcattc tctccttcag aacgatcggt ttcagtgaca cccgcaccat cattcatttg
     4801 atcggcagaa acagtagccc cttgtagaca gaaaaaaaga ccccctaata aaaggagcgt
     4861 ccaccatttc agagattttt ttcgcaaaaa aaccacctct tttttgtttt atcgttgttt
     4921 ttcattttct aacattgctt gaattttttc atcttgattt tcagtagaag aaacagccaa
     4981 taaccaacta tcaaacaaca catcaatggc aatcggttga tttcttccca aatgatcctg
     5041 gaataaacag gttcctgttt gtaattgttc catcatttct aaattggctg aattcacttc
     5101 catatcaaag aaggacaata gtttctctcg tgcttctttt tgtttcggac gaaacgcaaa
     5161 tttgtaagaa attaactctt ttttatcttc ttgatcgtaa tctttaaacg cttgcacaac
     5221 aaggtaaata tccgtattat tcgcacgtcc ttttcgcaag ctatcatcaa tcaaatagct
     5281 tccttgtgcg gtatcttcat acccttttgc ctcgtcataa ataatcgcag cgtcttcttc
     5341 tttgtttgta gaaaagatat acgtaaactt cataatgact tccataattg ccattcctgc
     5401 aagttgttcg ctatttaatc gacccgaatc aatctctttt tgtgtcggaa tgcgtattcc
     5461 ttgtgtccct aacacgttga tttgtgaatc aaaacgtatc ggcgtactgt gctcattccc
     5521 aatgagaatc tttcctaaac caacgctatg ccctaaaatc aatttagcta gttctttgtc
     5581 actttttcga atttcttcga taacttgact taacgaatgc ttacctggca tggtgtaaac
     5641 tacatcgatg gcgtcttgga tcaccgtttt cttgtggctc gctgtttctc gattggtatc
     5701 tacttctcct aacattccta acacattttt agcggtttga attgcctctt cttttggtaa
     5761 aaacaataga ggatcaagca tccctcgaca gctttcatct gaagataacg aaataaaatt
     5821 aattcgttca tacatagcca caaactctgg tatgtgtccg aatttttcaa gtgcctttaa
     5881 aaagaacttt tgggtttcat ttttcggatc aatataaaga attttttgac ctaaaaacat
     5941 cagccataaa aaaatatatt ttacaaggac cgattttcct ttacctggtg gaccaataat
     6001 caacgtattt ccattggtat gttccgcgcc ttcaatactt ttctttgtta aattgggata
     6061 ataccatact agtttactag atagcgctaa cgcttctttc gcagatttaa acttttttgc
     6121 aataacaatc cgtcctaaag gaaatccttt cttatttcct acttctttct ttaagtccaa
     6181 gccataatct gccacaaaac ctgtcgtagc gacctgctcg taactacgaa aacgttgcgt
     6241 acttccaatt aagcattgat taaacaacgt tagctgatcc gctaccgatc gataaaattt
     6301 gaaatctgta gactcaatcg caaattcaat atctttgact cgttcttcca attcttcttt
     6361 tgaagaagca gatacaacca gcgtgacggt agaataacac aatcgttttt ctttgcgctt
     6421 cagcttatct tttacatcca ttaaccgttc tgtaccaaaa tttaatacat cgtctgaatc
     6481 taaaatgccg tcaacggtct catattcttt ttcttgttca taaatccgtc cagccatttt
     6541 attaattttt cgttcatcag attttgaatg ctcaaatcga agtcgaatat gcgtatcaat
     6601 tggaaaagat aagctatcct gaagattttg aataaagcta ctcccataca tggctaaagg
     6661 agcgtccgtt tgacttaaaa acgtcgaata atgcgtttga ttcaactgtt caatcgcaat
     6721 gtatcctgct tcattcgaaa tgacgccctc gcaaatttcc attggcgtaa gctgtctttc
     6781 aggcaatttt tcttctgatc gatggaaaaa ataataataa atttgtccaa tctcttgggc
     6841 agataagcgc tctatcggct tataattgga caattccgta tagagctcct tttctaatgt
     6901 ttcatacgtt ggtaacacac tacttatagg aactcgttgt cccgtaatac gatagataaa
     6961 ctttttaaaa acatgcttaa gcaattgaaa atattcgatc ggatcagaca ctttcatttc
     7021 tgtagtgaaa cgcacaaaca gatacgttcg atactcgttt aattgcactt cgtcttttaa
     7081 aatctttcct gcctgttcaa agtacacttt cccaagatct gcgcattctc cctttaccaa
     7141 atctcgaatg gtttcttcaa tgtgcgtatc taggttaaat tgacgtggaa tattgataaa
     7201 atgatagtca tattcatcat gtccaagtat gccttcgcca tcttgaagat agttcttgaa
     7261 aaaatcaatg tcatttaaag gaaatacttg ggaagaaagt tgatagccta cccacacatc
     7321 atcatttttg gtcaaaacaa aatttcggat aatggcgtct atcggaaatt ctaatcgagg
     7381 aagcttcgtt tttttctttt tgaactgcca aatcccgata ataaagacga ccaaaagaaa
     7441 caaaaacgcc atttactcga ctcactcctt ccatttgtgt agggaatacg tcactttttc
     7501 atggaaaaac ggcacataca tttcatgttc aaagcgttgt ttccgtttct gataatagga
     7561 cgttcgccca attaaatact cgaaaaagtg tttattgtcc catttcattg aaaacaatgt
     7621 ccaaacgaga acaccaatcc caaaaatcat aatcaaccag gactttcgaa acagtgtctg
     7681 caagaaacta atttgattca catacgcaat caaaaatagg atcaaaagaa tgaagagaaa
     7741 taccccacct atgactaatt gttccatgcg aatgccatta gaaatccagg gaattttttg
     7801 tcctttaatc ccgtaaattt tgtgagggtg cttaaactcc tttgtatagt tgtattccat
     7861 gttcactcta cctcctttta caaaaaaaga agcgaccaga agttctaatc ttctgatcgc
     7921 ttttgcagtt tgtctttttc ttatgataat tgtatccagg gcacaatcat ttgcgttacc
     7981 cccacgttct cttcactatc cttaataaag ataatgttct ttagccattc accaatatca
     8041 acggcattcg ataacaataa gacgagcatt atcaaaataa agacgccaat aatggcaaac
     8101 gctgcccgcg caaagccttg ggtcgcataa gcaccaacca ttagaacaat cgcaacgatt
     8161 gccaatagcc aaatgacttg tccagataca tcatcaaata acgatttaag atcaaaaagt
     8221 ttcatttcca ttctcctcta agttcatttt attcatttaa cgtagtaaca aaataactat
     8281 cgccacttgt ttttacttcc attgaaaagt ttgattggaa ctcgtttcct ttctcaaaat
     8341 agaaacgata cttcccttgc aaaaagtagt ttccttcttt attttttact gcatgatcca
     8401 gttgtacatt gatcaattcg ccgccttcta accctttttc gttagaaatc aatgccaatt
     8461 tttcatcatt tttgacatat aactcaaaaa accgtttcac aaatgcttcc agcttgattt
     8521 cttcgctttc agtgaccgct tgcccagaag aataaaatcg attttcctga tagttcacag
     8581 aattggtatt cttactctca gaaagattca aaaattgaac gccatcaagt acttttaaaa
     8641 cattgttttg ataactgact ggaaaagaaa gttgactgct tttccaatgt tctccttctg
     8701 taaaagtaac ctcataaaat aggcgataca ttgcttgtgt caaatcgatt tcttctagtt
     8761 taataaagcg aacatctttc gctactcgat tggtagccgt cgttacaaag cctagatcag
     8821 acgcttccaa tccttgtgct aaataatgat tgacggaagc ctcccattcg tttcgttttt
     8881 ctggcgaata agtaaataac ctttcaataa aatgttgtcc ctcgtacttc aattgttccg
     8941 tagaagacaa ggtttggttg acttcagtta acaatgtttc tggattgact tgttttttca
     9001 ctgctaaacg cgttaatgta tccactcgtc caaagtttag gaggagcacg acacccatta
     9061 acagaaacaa acaaaaaaaa gcgcctgaaa atacactcat ggcacttttt tgcgaaaatt
     9121 ggatcattcg atctgacggt tctgttttct ttttttggaa caaaaaacgt ttcttttgtt
     9181 tcttttcctt ctgttgtttc ggtggcttag tttggaacgc ttgtggatta aattttgcat
     9241 tactcatgag aaatgccata ccgttctaac aataatttcg gtattttgtc cacaatcact
     9301 acttcgtgga caaccacact tgccccctc
//
LOCUS       DARBDN010000098         9281 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000098 DARBDN010000000
VERSION     DARBDN010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.099"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..435
                     /locus_tag="SCH06_002341"
     CDS             <1..435
                     /locus_tag="SCH06_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HEG1078876.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="SCH06_002342"
     tRNA            complement(759..842)
                     /locus_tag="SCH06_002342"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="SCH06_002343"
     CDS             1370..1870
                     /locus_tag="SCH06_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078877.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="SCH06_002344"
     CDS             complement(2060..2404)
                     /locus_tag="SCH06_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEG1078878.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="SCH06_002345"
     CDS             complement(2558..3478)
                     /locus_tag="SCH06_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEG1078879.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="SCH06_002346"
     CDS             3665..4156
                     /locus_tag="SCH06_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HEG1078880.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="SCH06_002347"
     CDS             complement(4180..6555)
                     /locus_tag="SCH06_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HEG1078881.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="SCH06_002348"
     CDS             6881..7507
                     /locus_tag="SCH06_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEG1078882.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="SCH06_002349"
     CDS             7530..8234
                     /locus_tag="SCH06_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEG1078883.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="SCH06_002350"
     CDS             8426..9259
                     /locus_tag="SCH06_002350"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEG1078884.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         2828 a         1791 c         1651 g         3011 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct t
//
LOCUS       DARBDN010000099         9160 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000099 DARBDN010000000
VERSION     DARBDN010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.100"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1872
                     /locus_tag="SCH06_002351"
     CDS             <1..1872
                     /locus_tag="SCH06_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEG1078885.1"
                     /translation="SAENMEEIKKMFPKSTWFGFTGTPIFPENRKQAKGQLARTTHDQ
                     YGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENKIYRKLKEVETYAEYSSEQIN
                     RMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNRLARKRAEFKQFGKQIDLAIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPDKTKGLIVTFRKPATMEKN
                     VEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEEQIGVYETVKGSLIEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHVFSNEWFVSEKELHASNLQYL
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
     gene            complement(3807..4472)
                     /locus_tag="SCH06_002352"
     CDS             complement(3807..4472)
                     /locus_tag="SCH06_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1078886.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            4652..6634
                     /locus_tag="SCH06_002353"
     CDS             4652..6634
                     /locus_tag="SCH06_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEG1078887.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6638..7276
                     /locus_tag="SCH06_002354"
     CDS             6638..7276
                     /locus_tag="SCH06_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078888.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            7304..7732
                     /locus_tag="SCH06_002355"
     CDS             7304..7732
                     /locus_tag="SCH06_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078889.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            8189..9100
                     /locus_tag="SCH06_002356"
     CDS             8189..9100
                     /locus_tag="SCH06_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEG1078890.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         3189 a         1400 c         1723 g         2848 t
ORIGIN      
        1 agtgctgaaa atatggaaga aatcaaaaaa atgtttccga aatccacttg gtttggcttt
       61 acaggtacac cgatttttcc tgagaatcgg aaacaagcca aagggcaatt ggcacgtaca
      121 acccatgatc agtatggaga ggtcttgcat acctatacca ttaagaatgc gctagaagat
      181 ggctctgtct taggatttca agtagagcat gaaaacaccg tggagccgac ttcactagag
      241 aataaaatct atcggaaatt aaaagaagta gaaacatatg cagagtattc atcagaacag
      301 atcaatcgta tgattgatca aatggaacct gtcaaaaaag aaagttattt ggacccagct
      361 gtttttgaag cagatgaaca tatccaaaaa gtcattcata aaatgttccg tccagataat
      421 gcctatacaa aatttgattt tcgaaatggc aggccaacga aatctgcaat cttaaccacg
      481 agttccattg acatggccaa aaagtattat cgggccatca aagagatgac gaaagagcct
      541 gattggttaa caaaagagtt tcccaatcag ctcattcgtg aaggacgaac gatggaggat
      601 cctgattttc cacgaatcgc tattacctat tcattagaag aaaatagccg agattcaagt
      661 gcccaacaag aagaaatgca aaaaattatt gaggaatata atcagtatta tgatacttcc
      721 tggtcattag cagacattga gcgttataac ggagacatca ataatcgttt ggcacgaaaa
      781 agagcggaat tcaaacaatt tgggaaacaa atcgatttag cgattgtagt ggatcgtcta
      841 ttaacaggtt ttgacgcccc tacgattcaa accctatttg tggatcgtaa tctagagtat
      901 gcaggattga tccaagcttt ttcacgtacg aatcgtacgt atcctgataa gacaaaagga
      961 ttgattgtga cgtttcgtaa gccagcgaca atggagaaga atgtcgagga tgcgacaaaa
     1021 ctgtattcaa aagcaaaaga agaatcaggt ttgatttatc caagttatca ggaatccaaa
     1081 aaaagattca aacaagcata tggtaagtta aaagaggttt catccatgga atccattgat
     1141 gaacatacgc cacttgaaat ccgtatcgag tacgtcaaag catttcaaga attgaatcgt
     1201 gcttatgaat cgttagtgac ttatgacgat tacaatgatg acatggtgaa atctccaact
     1261 ttgaacaatc aaattcaact tttggaagaa caaattggcg tgtacgagac cgtgaagggt
     1321 tcattaatag aggaagaacc agaaaaagaa ggagaagatt tttcaacgat cgaattttat
     1381 agtgaaaata ccactaagtt gtatgatatt gattcaactt atattgatca attactagga
     1441 acttatgctg cgaatagttc agatgcacga gaagaaattg aaaaagcttt ggctaaattg
     1501 aataaaacag aaggagtcaa agaagtttac cgacaaattt taaatgcatt tgatgtgggg
     1561 actttagata gtaatgaaga tatctttgtc attaaacgtc gctattttac acaagcgagt
     1621 gatgatttga ttcatgtctt ttccaatgag tggtttgttt ctgagaaaga attacatgct
     1681 tctaatctgc aatatctacc aggtgaagat ccaattccta atatgaaagc aattatcaac
     1741 agtaaggatt acgaaggata taaagccaaa catccagaag cgaagccatt taaataccca
     1801 caagaaatga agcgagcatg gcgtaaaatg ttagatgatg agttgattcc acttgagaat
     1861 gaattgaggt aaacgagaag agttaagaaa attgtacgat tcaaagatgg tagtcaagtg
     1921 gaagtgtaga aaatagggat agatgtcttt tatttgttca cattttataa cgaagtattt
     1981 aagacagcta ttgaataatg tttcctccac ctttttcatt catttacccc accccgttgt
     2041 tatatgaccg tgttttgaga ggaaccaata aaaagcatag gctaactagg ggttcctttt
     2101 tcttttgttt ttttggaatc cgcttaagtg aaatgtatct gaaatgaaac ggagataaag
     2161 tgattttttg ctataatgac aaggttttag ctgtttcaga taccatgtaa cccaaaatag
     2221 tttattgaga aaataggaga gtatttgata ctaactagta ggaaaaaatg agataaaaat
     2281 taaatggaat catttcaggt aatctcaaat aaaaaaatat acagtcctgt ggcactttac
     2341 ctatgggact gtatattttt tactctcagc gggcttgttt tgactccgtg tctgactccg
     2401 tcgtattgat tttaaatgat attcgatgac catttaacag gtcatttttg aaatttttgt
     2461 ctctatatga ctcagtttga taattattga tagatcaatt tgggtctata tcgaacaagg
     2521 gaataatcca ataaaaaatg atttagaata tcaaaataac aaaaaagagg actacctgta
     2581 ttcgtcctct tttttgacca gattttgacc agtctaattt acattctaat atattcatat
     2641 gagctaattt tttgattaaa tggtaagttt ttccttgttt gttttagttt aaactagtgt
     2701 gtaatttaaa aatctatatg gaagggtctg tggggtaata cttaaataaa ggctaggaac
     2761 ctgataacat caaggttcct agccttttta taataaaatg aagcgaaaat aatttctttt
     2821 aaagagccga gattatcagc tatataagag tgaatttgat gcaaaaaaca gagccgaaac
     2881 agtcttggtg ttcgtagctc tgcttatatg tttcgaattt aagacaaaga gttggcaaaa
     2941 gatgttgata aggaagataa gataactgtg ttatataaac taggtaacta actgtaacaa
     3001 gctaatttta agagattctt attagaagac gtttaggaat ataactaaga aaatgattat
     3061 acaggtaatt gtcatttcaa taatgttttc taattttcgc gtctttgttt taagaaaaag
     3121 gccagaatca gttggaaaaa agttcgtacg atagtgaaga ggggcaaaat ttcctactaa
     3181 tattcccact aacaagagat aaaacggcca ggttggtgtg attcctctat aaaaaaatgc
     3241 ccatgctacc gaaatcccat agattaacaa ctgaacaatt tttacaatga aaaaattgtt
     3301 ctgccattac tcaaagtctc ttcctccttg tatcgtttat ttgtttcatt ttatcattat
     3361 gataggcgct tgaacaatcc attttgtatt ttattgagta ctcttggata aactaccagc
     3421 gattatcata tttatttatg ttactgtaag ccatcatata aaagtaaatg agcagatcat
     3481 agaaatataa aaaagaacta aaattgatct aaattatgtg cagcttgact acgtaccaat
     3541 ctatattact tactagattg gtcgttaatc tattcggatc gaatgagcaa aatatttttg
     3601 tgaatgtcca tccttgatta tgattccaaa aagaatcatt gggaggctgt ggcgtaaata
     3661 ttatactata agccagaaat acctatcatt ctgaactttt ttatttagga actttcatct
     3721 caaggctttt tcaattaatt tgtacccctg ttttttggat aagatcatgt gcattgattt
     3781 tttctatctc tacgttcatc tcctacttaa tgcctatctg gctcctgagg gcttcttttt
     3841 aaggcgtcgt catagtcttg gctgaggatt tcttggtaat ctgagggaat ggcttcccaa
     3901 gtgagcaggc gaacgttcat gacgtgtttt cctttgtgtt tgattacagc atggtttttc
     3961 tctttttcta cctctccagc gtgaaaagac agccatgtac catggccaaa gatatcatta
     4021 catacccaac gttcgatgga attgtccacg tatcctacag ggagtgtggt atagccgatt
     4081 tgtggtttca aaaaaggatt gaatcgatcg atcgtttcat ttttgtattg ataattgata
     4141 agaaaaagat agaccaaaca aaagacgagc agaaagaaag atagtgtctt tttgagtgag
     4201 aagggttgtt ttgatgaata agatttcttg ttaacaagag gttcatctgg caatgttggt
     4261 tctattgatt cggtagctga ttcaatagaa ggaaaatcaa tcggcagacc taaagtatga
     4321 tgtaaaagtg acagcatttc aaggtctggc attgtacgag aattttccca actagaaatc
     4381 gttttatcgg aaacaccaat tttttcgcct aattcttttt gcgtaagctt acaatttctg
     4441 cggtaagttc gtattttttc tccggtgttc atcttcttct cctttcgatt ctacagtata
     4501 tagatttatt ctacatgacc tatacacttg atagatacgt ttttttgatg aaaaacggta
     4561 tgattttatc aaagaatcat ttaagtaagg gagagtggtg ataatcaaaa aaaagttcac
     4621 agttttactc acaatcatag tgaccggtat catgagtggt tttgccttgg ttagtataaa
     4681 taaacaggta ctctatcgga caaatgaatt tttccatcaa acagatactt atactccgat
     4741 tcgattgcca caacatttta ttgggcaaga agaatatgag cagctaatca tggtatttga
     4801 aaatgtctca tcagaaactg agctttctta tatgaaaaaa acagtaaatg aatccaatga
     4861 agtagataca tcttggaact tcaagataca gccaaagctt gaaatgacat tgtattatca
     4921 aggggatgtc aaatcttctc acgagaaggt accctattct aatacctcct ttcgcgtaac
     4981 gtccattgaa gaatcgatca aaataaaaga ttttgaaggt gaatttttct tgatgacgag
     5041 agaaaaagaa gcctatgaac ggttcatttc actattcact gatcgattca atcaagcatt
     5101 tcacactgat tatgccacta atatttttga agactttgaa aatagctatt cgtattcggt
     5161 tatttcaaat acagacgtat ataattatcg agtgtattta actattggat tgattctttt
     5221 attccttttg ttatcatcct ttttcttatt gatgaataaa gaaatcagtt tattgttgaa
     5281 taatgacttt tcattacatc aagtattgtg gtgtttattg gggaaaaaga aaatcattat
     5341 tacattcata attgcaggaa tcattggtgg ttttattttt atgtattata aggagcaatt
     5401 tctttatttg ttccagatgt acgttttctt gttcagcgga atatatggta tctctttgat
     5461 ttctctttta ttagttgaaa aaatcgcttc gttaagagaa gcgttcaact atatccaata
     5521 cattcttttt acatttggat tgttgttttc tcttcttttg accgttgcca atgtcgaatt
     5581 agcaactatc gttttttctt cttcacagtt agctgtttcc catgaaccac caaaagaaat
     5641 cgctggtgag gactatcatg tattttatcc agtaaccatc gggaaaaacc acgtggattt
     5701 tatttattcc aatcgttttg catcagcagc agatcaggaa ttatatgaaa ctttgaataa
     5761 aaacggaagt atattagtca atgtatcaga ttacttgaat gaagaaaatg aacagtttgg
     5821 cagagggata aaaataaatc tgaattatct taagaaattt cctttgattg atgtctctgg
     5881 aaggttgatc caaataaccg aaaaagaaac gcaccctgtt atattgatcc ctgaacgata
     5941 tagacataca gatttaaaaa atgacctggc gcaaataaca gaatattatc aagaaatcag
     6001 tgaaaaagaa ccgaaatttc tatttataaa aaacaatcaa cccatttata catttattcc
     6061 ttctatcccc tggatcgaac attatccggt tgttgaaata ctgacattga aaaacagtat
     6121 gtatttggaa agaaatattc tcagcggaga aatctatcca ccgttaaaga tcaagatagg
     6181 ctctttgtcg aaagaaaggt tatttgagct gattgaagaa agtcagttac gtgataactt
     6241 gcagttatca tttccgtata ctcagactga agagatagct gtcaaagtgt taagcagatc
     6301 atttcattac ttgatacaga tatttttact cactttcttt tctttcttct tgttgagcta
     6361 tgtcatgtta tgcatatatt ttgtctacaa ttgtcggaaa atcgctatct ttcgttcaag
     6421 tggttattcg ctctttgaaa cgtataaaga tttcttcatg atgaacctca tcaaatgggg
     6481 aacgacaagt gtaatcttcc tttttcttat agaaagagag cctaaatatc tttttaatat
     6541 ttttttcttt agcttcattg attttattct ttcagttgtt tttattttgt ctacagaaaa
     6601 gaaaagtcag ttattgctga tgaatggagg ttaacaattg gagccgttga tagtgataaa
     6661 aggtgcgaaa aaaatcattc gaaacaaaac gattcttcat ttggatcgtt tcactgcgga
     6721 tgctggggat cttgtgactg ttgttggaga aagtggagca ggtaaaagta cgttattgaa
     6781 tatattagga ttgaatgatc agttcagttc aggacaattc tatttgttcg atcaagagac
     6841 gaaacaatta actgggagag agaagcgctt gataaaaaga aataccatat cttttctttt
     6901 tcaagatttt gggttgattg aatatgaaac aatcgatttt aatttagata ttggattgaa
     6961 gttttcgaat ttaaatgttt cagataagcg aacagcaaag tatgaggcat tgaaaaaagt
     7021 aaatataaac aagaagctaa gtacgcctat ctacacatta tctggtggtg agaagcaaag
     7081 aatcgcctgt gcgagagtct tattgaagaa tagcaaaatc attttagccg atgaaccgac
     7141 tgggtcattg gataaaagaa ataaggataa agtagttgaa atcttatcgc aacaagcttc
     7201 ccaaggtacg ttagttatcg tagtcacgca tgatccatat ctgaccaaaa taggaaacaa
     7261 gaagatcatg ctttaaaaat caaaaaggaa aggatgtcgt tttatgaaaa aagcagttat
     7321 tatttgtgca ctagggatag gttttgttgg aggaaacgct atgtcatctg aagtggaagc
     7381 aaattcagtt cacggtgaaa tctattacaa atctttaaag ccaggagaga ttcattttga
     7441 tgctaaaggt aatattatta agtcaaattt accagtagac cgggaaattt ctagaacagc
     7501 aattaatcat agctctggaa gatgggttta ttatagtgat acaacttgta cgagaaaaac
     7561 aggtcattct aaccactata gtcgtgtcta taatcgtcac ggtgcaaaag cgaaagttgg
     7621 aaactctatt cgatcagcaa atgcaacaaa aggagtatgg gcctatgcaa gtgcgacagg
     7681 aaatagaact gacacattct catgttggta caatccaacc ggttggtatt aagtatccaa
     7741 aagtttatat aaaatagaaa aaacatataa tgaaacagcg ttaaaagtta tttttggtag
     7801 ttttaatata ttcattttta gttgtataaa aatatatcat aataaaaaca acaaaaaaat
     7861 gtctggaaaa tcgaacataa aagtgtctga tttgaatatc ccagcagcgg aagaagaaaa
     7921 acaaaatcga taacatttgt tctaagaatt agttacgtta aatacggaac gcaagataga
     7981 cttgaaaaac ggtaacaaaa gaagtagtat attaaggtgt gatgtgctac ttgacattta
     8041 ttctgctgag cgaactttct ggattgtgta gccttatatc tattcaggac gtatcgagca
     8101 gattagtaaa ggtgttcttg atgattttca tcttgaacac ctttgttttt agcaattcgc
     8161 aaaaaacgaa aagtaggaga attgataaat gaaaaaaaga tttttagcac ttgccatcgt
     8221 actaggcact ggcttattgt caggctgtac gaatgccggt gaaaaaacag ccgttagtta
     8281 taaaggcggt acaatcagcg aacaagaagt aatggatagc ttgaaaaaaa tgcaaggagc
     8341 agattccgct gtgcaacagt tgatcgttta tcaagtattt gaagataaat atggagatga
     8401 cgtatcaacc aaagaaatcg attctcaata tgatcaaaca aagaaacaat tgggtgattc
     8461 atttgattca caattgaaat ctgcaggtta cacagaacaa acattcaaag acagtatcaa
     8521 acaaagtcta gcctttcaag aaggtctaaa gaaacatatc aaattgaccg atgaagattt
     8581 aaaaacggct tgggaatctt tccatccaga agtggaagct caaattatcc aagtagcaag
     8641 tgaagatgat gcaaaagatg tgaagaaagc tgctgataag ggagacgatt tctctaaatt
     8701 agccaaagac aagtcaactg atactacgac aaaagaagat ggcggaaaag tgaaatttga
     8761 ttccactact acaacggttc cggcagaagt caaagaagca gcctttaagt tgaaagatgg
     8821 tcaagtttct gatgtgatca cttctaccaa tgcttcaact tatactacgg aatattatgt
     8881 ggttaaaatg gtgaaaaacc aaaacaaagg caacgacatg gataaataca aaaaagaatt
     8941 gaaagaaatt gcaacagaca caaaattaag tgacagtacc ttccagaata aagtaattgg
     9001 cgaagtattg aaagacgcta atgtaaaaat caaagacaaa gactttgaaa atgttttgag
     9061 tacattcact tcagattcta gtacagcaag tagtaaataa gcggtataaa taaaaaatat
     9121 gaactattta aatcaataaa actgttcatc taaatctttt
//
LOCUS       DARBDN010000100         8675 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000100 DARBDN010000000
VERSION     DARBDN010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.101"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1101
                     /locus_tag="SCH06_002357"
     CDS             <1..1101
                     /locus_tag="SCH06_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEG1078891.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1609)
                     /locus_tag="SCH06_002358"
     CDS             complement(1280..1609)
                     /locus_tag="SCH06_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEG1078892.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="SCH06_002359"
     CDS             complement(1599..1871)
                     /locus_tag="SCH06_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEG1078893.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="SCH06_002360"
     CDS             complement(2322..3125)
                     /locus_tag="SCH06_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEG1078894.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="SCH06_002361"
     CDS             complement(3103..4227)
                     /locus_tag="SCH06_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1078895.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="SCH06_002362"
     CDS             complement(4243..5058)
                     /locus_tag="SCH06_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEG1078896.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5920)
                     /locus_tag="SCH06_002363"
     CDS             complement(5048..5920)
                     /locus_tag="SCH06_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1078897.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="SCH06_002364"
     CDS             complement(6005..7294)
                     /locus_tag="SCH06_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEG1078898.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="SCH06_002365"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="SCH06_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2691 a         1850 c         1371 g         2763 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacag
//
LOCUS       DARBDN010000101         8572 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000101 DARBDN010000000
VERSION     DARBDN010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.102"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..776
                     /gene="menA"
                     /locus_tag="SCH06_002366"
     CDS             <1..776
                     /gene="menA"
                     /locus_tag="SCH06_002366"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEG1078899.1"
                     /translation="YMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFVIG
                     VILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVYVN
                     TFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRDIE
                     NHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKHLD
                     QFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1590..2936)
                     /gene="gor"
                     /locus_tag="SCH06_002367"
     CDS             complement(1590..2936)
                     /gene="gor"
                     /locus_tag="SCH06_002367"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEG1078900.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(3070..4323)
                     /locus_tag="SCH06_002368"
     CDS             complement(3070..4323)
                     /locus_tag="SCH06_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEG1078901.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(4329..5252)
                     /locus_tag="SCH06_002369"
     CDS             complement(4329..5252)
                     /locus_tag="SCH06_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEG1078902.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(5473..7965)
                     /locus_tag="SCH06_002370"
     CDS             complement(5473..7965)
                     /locus_tag="SCH06_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEG1078903.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(7972..8439)
                     /locus_tag="SCH06_002371"
     CDS             complement(7972..8439)
                     /locus_tag="SCH06_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEG1078904.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         2354 a         1814 c         1422 g         2982 t
ORIGIN      
        1 attacatgga ttatgaaaag gctcattctg aagtatataa gtatgaagaa aatgtcattg
       61 gccgcagaaa tctatctcct gtattgattc gaaacatgat tttagctatg attgcatttg
      121 tttttgttat cggcgttatt ctaacgatca atacgggttg gcttttactt ttgatgggat
      181 ttatctgttg ttttattgga gtattctata cattcggacc gattccttta tctcgaatgc
      241 ctttagggga aattttcagt ggggtgacta tgggccttgg aatttttgcc atggtcgttt
      301 atgtcaatac attcggttca gatgtctatg atctgacagt caacttttca tctggacaat
      361 ttgatttggt aggaaatctt tgggctatag cagcaatcgt attagcttcc ttacccttgg
      421 tgtttacgat tgccaatatc atgttggcta ataatttgcg ggatcttgac cgtgatattg
      481 aaaatcatcg ctatacacta gttttttata tcggacgtcc tgcgggaaca gtcttattcc
      541 agctattgat gtatgcttgc tatttcgtga ttttaatggg gttgttgagc ggtatctatg
      601 aatggccgat cttggtcacc ttcttgacct tgccaattgt gaagaagcat ttggatcaat
      661 tcaagcaaac gttaccccag cctatcagtt tcagctattc catcaaaaat atggtcttat
      721 tcaatgccag ttatgtattg gggctattac taacaatcat tatgcaagcc atttaacagc
      781 atgaagaggt tgtgaaaaaa ctgccctgca tcaagtaata agaacagcca aataaaaata
      841 gctccttata tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg
      901 tttatcagga ggttgtgaaa aagtcgctta gtttcgagta ttaagaaaaa ttttgtgaaa
      961 atggctttcc acatttttgc ataaatttgg cttaataccg agaaactggc ttttgaacac
     1021 cgtttatcag aggttgtaaa atcagtgttt tgtcctgagt attagagaaa caaatggaaa
     1081 aatagttcct catattttgc cgttttttga gctaataccg aaggacagct gattgaacac
     1141 tatttgttcg gaaaaagtga ctaactatga cacaattttt ttcacagtcc cttttttcac
     1201 ttgatttgat tcgtaccagc gaacttgacg agaactttct tggtttggta actatatggt
     1261 attcttttaa catcctcgtt tgcttcttct aatttattta tacaaagtca cactttttta
     1321 aacatctgtt cttcgataca tttctatttc ttttaaacat cgataccaat attttgaact
     1381 taagagtgca taccaaatgg attcatttac tcttcgtcag ttacgaagat aatcaaaatc
     1441 tccaacttcc ctacttattt cgttttgaga attatcgaag caatcttaca taaataacta
     1501 aaaaacaaaa aaccagaaaa tcagtatact gattttctgg ttttacatgg tttgttcaat
     1561 aaaaagctgt tggaactgtt aatattaaat tatcgcatcg ttacgaattc ttccgctcct
     1621 gttggatgga tggctactgt attgtcaaag tcttctttag ttgcacccat cttgatagcc
     1681 acggcaaaac cttgcagcat ctcatcgaca ccaacaccaa tagcatgtaa gccgacgatt
     1741 ctttcttctt ttccgacaca gatcaatttc atttcgcatt tttggcgata atcatttaat
     1801 gcaaagtaca ttggggtaaa gcgtgaacga taaactttca attcattttc gccatatttt
     1861 tccaatgctt cttcttctgt caaaccaatt gttgcaattg gtggatgcgt aaagacgact
     1921 gtcggaacaa gtttatagtc aagataagaa tctttctttc cattaaataa acgttctgat
     1981 aaacgtctac cagctgcgat tgcaacagga gtcagatcta atttaccgat cacatcacca
     2041 acagcaaaaa tatgttcatc cgttgtattt tggtatttat ctactttgat aaaccctttt
     2101 ttgtccaatt ccacatttgt attttccaga cctaattttt cggtattcgg tacacgtcca
     2161 ccggcaaaaa gtacacaatc accagttaag gtttcaccat tttcaaatag caccgtatat
     2221 tcgtcattgt ttttagtaat ttctttagca atatgatgtg cgtaagtttt tattccagct
     2281 tcttggtaca tttggatcaa attgtccgaa agcattttat caaacgttct aagtggtcgt
     2341 tcttttcgat atgcccacat gacttcacta cctaaaccac gaaatacacc tgaaagttca
     2401 gccgcaatgt atccagcacc taaaacgatt gctctcttag gtaactctgt taattcaaaa
     2461 aatccatttg aatcaattgc gtattctcca ccaggaatgg tcattttact tgcacggcct
     2521 ccagtagcga tcaagatttt aggagcacga taggtttcac cgtttacttc gatcgtttga
     2581 ctatcgataa aagtagcgta accttttata gcctcgacat gattgctatc taatcctctt
     2641 tgataagcac cgtgtagaaa atcaatatat ttttctcgtc tttctactag accggcgaaa
     2701 tcaacatttt ttaaatctgc ttggataccg taacttgagg catctcgttc aattgtttcc
     2761 aaaatcgtac ttgcttgcca cataactttt ttaggtacac aaccgacgtt gacacatgtt
     2821 ccgcccaatt cattcgcttc aatcagcaaa acttttgcgc catgcatccc tgctctgttt
     2881 gctgaagcaa taccgccaga gccgccacca attacgatgt aatcatatat ttgcattttg
     2941 ttcctcctta ttgaagagat caatcaaaac ctttatttaa cgatcctttt tctacagaaa
     3001 acaagtgtaa cacttttctt gaattttgta tgcgaagatg cttaaaacag ggatatatca
     3061 gctttttcct tatttacgtt ttcggatcat atctccaggt ttcaccggct gtgcgactgg
     3121 catagttaaa atcatcattg gatttggtgc tcggtcaatg gattcgcctt cttcattatg
     3181 cataacttca acggtttgac tgaaatgact gaatcctgga ccataaaatt cgatttcatc
     3241 tcctacagaa aacaagtttc tctgacgtat cgtagcaatc tgtgttgcct catcataaga
     3301 taatacttca ccgacaaatt tatatactgg gattttacga cgttcaccga ataattgttc
     3361 gttttcagtt ggtgtattgt agtaaaaacc tgtagctaat tctcgttgtg ctactttcca
     3421 taactcgtcg atccattctt gcttgcagac atagttttca ggatcttcca tataactgtc
     3481 tacagccgct ttatagacat ttgacaccgt agatacataa tggatcgatt tcattcttcc
     3541 ttcgatcttg aagctgtcta cgccgttttc aatcaattct ggaatatgtt cgatcattga
     3601 catatccact gcactcatcg agaattcttc ttccacttcg cctgtatcag ttaaactgtt
     3661 tcgttcttga ccaaaaggca tatcgaacaa tccatacttc cagcgacaag attgagaaca
     3721 tccgccacgg tttgcatccc gcatcgacat atggttggac aatgtgcatc gaccagaata
     3781 agagatacac atggcaccat ggataaatgc ttcgatttcg gtatccgtat ttttacgaat
     3841 ctctgccact tcctccattg aaacttcacg agctaaaacg acacgttcca acccttcttc
     3901 tttccagaat tccaatgtct caaaattagt tgctgaagct tgagtggata aatggatcgg
     3961 cagacctggg gcttctgtcg cacaaatttc gatcaaagct ggatcagaaa caatcactgc
     4021 agaaataccg acatcacgca aactgcggaa aaattcccct gctccatctt catttccttc
     4081 atgggtgacc atattagcag caacgtatac cttcgcatca tgttcttttg caaaagcaac
     4141 tccttcagcc atttcttcat aagtaaaatt acctgcacgg cttcttaaac catatgcatt
     4201 cccgccaata tatactgcat ctgctccata atggatcgcg gtttttaact tttccagtgt
     4261 tcctgctggc gctaggattt ctggtcgttt caattttctt tttactgtca tttctttcat
     4321 catactcctt atttgatagc agaaggatca atataaaaga atcctgtatc taattcacgg
     4381 ttttcaggat gcaatttact gatttcgcta gtcatttttt ccgctttttc ttgatcccag
     4441 ctaccttcta aaatttgttt ttttgcttcg gcgaatagtc gagtgatgtt tacgaatttt
     4501 tcgcctggag taaataatcc gtccaatttc catgtacagt aatgatgctg ataaagttca
     4561 ttcaattcat tcgagagatt cagatcattg ctggcaaaaa tatgtgtgcc atgactatct
     4621 tcataaatag aataatgtgt ctcttctttt ttaggttccg agataaaaag acctctttca
     4681 cgatcttttt gttcgtcttg tttcgtatag ttatagtaat tctgtagcag tggacgtttg
     4741 gattgatgga tgcatgtagc accatacaca agggtttcta caggaatatc gagtttttct
     4801 tccatcgcct tcatctcttc aaaaggaact tcacgagcaa gtactgctcc aactgcgcct
     4861 tttttcgccc agaaattgat ttgacgtgcg ctcgttacta atgtttcagc atcataaata
     4921 tacggtatac gcaattcagg attttttttc atcgtataaa taatacctgt atcaccaact
     4981 gtgatcacat ctacgtttat ttcttttaaa aaagccaaat attcaggtac atttttcatt
     5041 ttttcaggat gaatgatccc atttacagca atattcgctt ttttaccata cttgtgtgct
     5101 aattctacca attgtcgctg ttcttctcgt gtaaatgaag caggcagacg caatccaaat
     5161 tgctcttcac cgaaatatag tgtatctgca cctgcagcaa gcaactgttc tgcttgttca
     5221 atagtttcta ctgtggttat gagttcgatc ataattttct cctcctacaa cttcataata
     5281 gtagcatagc tctaaaaact ttccaatact tcttctattt aaagtcggat ttttgaaaat
     5341 tatttcacaa aaaatcaaaa taaagttcga tatattctgt ccaaatataa aaagagattg
     5401 tgacaaaaat cttgtcacaa cctcttaatc aagtcttact attataaaaa ttcagctaca
     5461 caggccaagt aactataggg aacctactgt ttccttttta ggtccgcgaa cattcaatgt
     5521 gatcttacct tttgaagcac ctactgttac gtggtcacct aaacgaattt ctccgccaag
     5581 caaagcctcg ctcaatcgat cttcaatttc tttttgaagt gcgcgacgga ttggacgtgc
     5641 accatattca ggatcaaatc cagctttccc gatcacatcg attgcagatg gtgtgatttt
     5701 cacttgaata tcttgttctt tcaatcgttt gataatcgct ttgctcatga tttggacgat
     5761 tgtatggatt tcatctttac tcaatgaatg gaagacgaca gtctcatcga ttcgattcaa
     5821 gaattcaggt cggaaagctt tctttaactc ttctaagata cgtttttgca tggctttgtg
     5881 atctttagta acatcttgga cattgaatcc gacatttttt tcttctcgaa tttgtgtcgc
     5941 tccgatattt gaagtcataa tcatgattgt atttctaaag tccacttttc tacctttaga
     6001 atctgttaaa tgaccatcat ccaatacttg cagaagtaaa ttgaaaacgt ctggatgtgc
     6061 tttctccact tcatctaaga gaatcactga atatggtttt tgacgaattt tttctgtcaa
     6121 ctgtccacct tcatcatacc ctacgtatcc tggaggagac ccgattaatc ggcttgtact
     6181 gtatttttcc ataaattctg acatatcaac acggatcagg gcatcttcac ttccaaacat
     6241 gacttctgaa agtgctttgg ccaattctgt ttttccgaca ccagttggtc caaggaacat
     6301 gaatgaacca attggacgat caggatcttt caatccgctt cgtgcacggc ggatcgcacg
     6361 tgaaactgct ttgacagcct catcttgacc aacgacacgt tcatgcagaa gtccttccag
     6421 ttctaacaag cgttcgcttt cttttttctc caactgctgt agagggacac cagtccactc
     6481 cgatacaact gtagcaacat cttcttctgt tacacgatca gaataacctt gctcctgttt
     6541 tgcttcaatt gcagaaactt tttgcagctt tttacgtagt gctttttctt gtctgcgtaa
     6601 ttgagcagca ttttcaaagt cttgtttttg gatcgctgct tccttttctt gtactagttc
     6661 atcgatttct agtttgatca cagttgattt tgttaagtga tcggtttgat ccaaacggac
     6721 tttcgctgct gattcatcga tcaaatcaat tgctttatcg ggtagttgac gagaagtgat
     6781 ataacgaaca gaaagattga ctgctgctcg tacagcttca tctgtgatct ccactccatg
     6841 gtgctcttca tatcttgtac gtaatccttg aagaatcact tctgcttctt caggagttgg
     6901 ctcatctact tgaatgcgag caaaacgtcg ctctaatgca gaatcttttt cgatatattt
     6961 ttgatattca tctagggtcg ttgctccgat cgtttgtaat tctcctcgag ctaacgccgg
     7021 tttcaagata ttcgaagcat caattgctcc ttctgctcca cctgcaccaa ttaaggtatg
     7081 caattcatca atgaataaga ttacttgacc atcattatag atttcgtcga tgaccttttt
     7141 cattcgatct tcaaattcac cgcgatattt cgtaccagca accaaagatc ccatatcaag
     7201 catcatcagg cgcttttctt gcatgtcttc tggcacttca cctaaaatga ttttttgagc
     7261 taacccttca gcaatggctg ttttgcctac accaggttca cccaccagta cagggttatt
     7321 ctttgtccgt cggctaagaa tctggataag ccgtttcact tctctcgaac gaccaacaac
     7381 tgggtccagc ttgttttctt ttgctaattt cgtcaaatca cgtgctaatg aatctagcgt
     7441 aggtgttcct tgcggtgttt gccgtttatc ttgtacattt acatttctac gacgattcat
     7501 tccttttcca gcagaatcac cagctagccc cattttttgt ttcagaactt gacgggcttt
     7561 tgaaaggctg atacctaagt tgatcatgat tcgagtagcc atgatacttt catcttttaa
     7621 taagctcatc aaaatatgtt ctgttccaac tttttgagaa ccagttttct tcacttcgct
     7681 gctagctaaa gcaaaaactt gtttcattct tggtgaatat ggaagaaaga ctcctttagg
     7741 gtaagaacgg ataccaccat aaccaatcag atgttcaatt tcttcataaa tttccgtttc
     7801 attcaaatcc atttcacgta atacttttcc agcaattcca ttttgctcga ccactaaggc
     7861 tagtaaaaca tgttctgaac taactgattg atgtttcaac cgttttgctt cttcttgtgc
     7921 aatttctaat actgcttggg ctctttcagt aaaaagttct tccatctaat ctcacttccc
     7981 atcttcataa cttaaacgtt ccagaaatgc tcggagaatc cgagcacgtg tatgatcttc
     8041 atattcattg aaattcaatg tgttttttgc aattgcactc aacatcaagt ttccttcttt
     8101 ttttgtaatt atttggtctt cataaagttt ttgaataata gcaaaagcat ttttctcact
     8161 gattgtatca tcaaataact gatttatctg ctcaagtaat tgttttttat ctgaaatcct
     8221 tacttttgca attcgtatat aaccaccacc accacgtttg ctttctacta gataaccacg
     8281 ttggatggta aaacgggtat taatcacata gttgatttgt gaaggaacac agttaaagag
     8341 gtctgccatt tcaatccttc gaatctcgat catttcacta ttttccagaa ttttctttat
     8401 atatgattca attaaatccg aggtattctg atgtgccatc ttattcattc cctttgacta
     8461 atattgacct taattataac gaatttgata atagaaagaa agaagaacgc tttttgttaa
     8521 ataaatcctt tagaatcaac aaaaaaaaat acggaatata ctattccgta tc
//
LOCUS       DARBDN010000102         8511 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000102 DARBDN010000000
VERSION     DARBDN010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.103"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            476..1339
                     /locus_tag="SCH06_002372"
     CDS             476..1339
                     /locus_tag="SCH06_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEG1078905.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="SCH06_002373"
     CDS             complement(1468..3090)
                     /locus_tag="SCH06_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEG1078906.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="SCH06_002374"
     CDS             3339..3860
                     /locus_tag="SCH06_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEG1078907.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="SCH06_002375"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="SCH06_002375"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEG1078908.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="SCH06_002376"
     CDS             5941..6759
                     /locus_tag="SCH06_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HEG1078909.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="SCH06_002377"
     CDS             complement(6862..7059)
                     /locus_tag="SCH06_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078910.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="SCH06_002378"
     CDS             7228..7806
                     /locus_tag="SCH06_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEG1078911.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="SCH06_002379"
     CDS             7901..8038
                     /locus_tag="SCH06_002379"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078912.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2577 a         1521 c         1670 g         2743 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag g
//
LOCUS       DARBDN010000103         8494 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000103 DARBDN010000000
VERSION     DARBDN010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.104"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..173)
                     /locus_tag="SCH06_002380"
     CDS             complement(<1..173)
                     /locus_tag="SCH06_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1078913.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="SCH06_002381"
     CDS             complement(593..1714)
                     /locus_tag="SCH06_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HEG1078914.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="SCH06_002382"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="SCH06_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HEG1078915.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="SCH06_002383"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="SCH06_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HEG1078916.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="SCH06_002384"
     CDS             complement(4304..5215)
                     /locus_tag="SCH06_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1078917.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="SCH06_002385"
     CDS             complement(5232..6239)
                     /locus_tag="SCH06_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEG1078918.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="SCH06_002386"
     CDS             complement(6236..8365)
                     /locus_tag="SCH06_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEG1078919.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8494)
                     /locus_tag="SCH06_002387"
     CDS             complement(8370..>8494)
                     /locus_tag="SCH06_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1078920.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DARBDN010000104         8140 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000104 DARBDN010000000
VERSION     DARBDN010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.107"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            384..572
                     /locus_tag="SCH06_002388"
     CDS             384..572
                     /locus_tag="SCH06_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HEG1078921.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            650..1663
                     /locus_tag="SCH06_002389"
     CDS             650..1663
                     /locus_tag="SCH06_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1078922.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYWGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(1730..2764)
                     /locus_tag="SCH06_002390"
     CDS             complement(1730..2764)
                     /locus_tag="SCH06_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1078923.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            2879..5104
                     /locus_tag="SCH06_002391"
     CDS             2879..5104
                     /locus_tag="SCH06_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEG1078924.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5122..7005
                     /locus_tag="SCH06_002392"
     CDS             5122..7005
                     /locus_tag="SCH06_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HEG1078925.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            6986..7960
                     /locus_tag="SCH06_002393"
     CDS             6986..7960
                     /locus_tag="SCH06_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HEG1078926.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         2638 a         1478 c         1713 g         2311 t
ORIGIN      
        1 tagttagtct acattatttt ggcgatttgc caataaggac tgttgagttg tgcaaaatca
       61 aatctgggtc agaatgaacg tcattctgtc tcagattttt cgttatttca atttgattaa
      121 ctgattgatc aaaaagattt ttattttcat attctcaaat gattcaacac taaatataca
      181 tgtttgacgc ggaaattatt attcgatttt ggcggcatca ggggggatga cgacgtagca
      241 gacccattat tttactcaag aaaatgtccg tgcctattat ttagaatacg atagtgaacg
      301 tgctgggagt tttgttcttt tagagaaagt ctctgaagat aaattagttg tcttagattt
      361 tgactgtaac gaaaaatggc gaaatggaag agcaccagca agtgattgac cggatctacg
      421 aagcgacacg atatctgcct ttggatcgtt tgtgcttaag tcctcaatgt ggatttgctt
      481 caacagaaga agaaaatgtt ttgtttgaag aacaatggaa aaaatttctt ttgtcaaaag
      541 cattgcagaa gaagtttggg gaaaatcatt aaatcatcta ggagagcttg ataggaaata
      601 acactatggt ataatcagaa tgcttaatac taactactga gggagcctta tgaaaaagaa
      661 aattcttaaa tttatcggat ggttcttcgg aatcattctt gggatcgcgt ttgcaatctt
      721 tcttgccttc cagctttccc ccagacctgg agcattcttg atcaaccata tgttttcaaa
      781 tactgttcaa atcactgata aaaaaacgtt cgatcaagca gaaaaaaacg tggcgaaaaa
      841 aacagatttg acgtatgagt ccaagtataa agagaatact tatgacatct actatccaaa
      901 aaacagcaag gggcctgttc ctgttctatt ttgggtacat ggtggaggat tcgtcggcgg
      961 agataaatcg ggtgtcaaag aatttgcgac aaaattagtt tcagacgcca acatcgcagt
     1021 ggttgcgatg aattatgaat tagcgcctga ttcagaatac cctaatcaag ttcttcaagt
     1081 gaatgaactg atcaaagatt tattagctga agaaaaagac gacaaattgc tagacatgga
     1141 acaattattt tttggtggag atagtgcagg ttcacaaatc gcattgcaat atgcagctat
     1201 acaaacgaat gatgcgtatg ctaaacaaat gaaaatcaaa cagctacttc caaaagatag
     1261 tctgaaagga accatttctt attggggacc tgttgatttg aagctaacag cacagcagca
     1321 ttcggatgat cgatttatga agtttttcgt caaaaccgtt gcgtggtcgt tgattggaac
     1381 aaaagattgg aaaacgagtg agcaattgaa agaagctagt gtggctgacc atgtttctaa
     1441 ggaatttccg ccaacgtata taactgacgg aaatgcatac tcattccagg agcaaggtca
     1501 agcattagaa aatcggttga cagaattaaa ggtacccgtg caatccttgt tttatacaga
     1561 tacaaaaaaa gagattaccc atgaatacca atttgattac acgctaaaag aatcgcaaaa
     1621 ttgttaccag cagacattgg attttgtgaa taagtataag taagaggttg tgaaaaagcc
     1681 gtttcgtttt gagtatgaag aaacgaagcg gcttttcaca acctctcttt caataccttt
     1741 ttgttcttgg gataaaactt tccctaacaa tcaatcgtgc aggataagtc aaaatgattg
     1801 gttcgtcccg tataccgtca attcgctcca atgccattcg aacagctgct tgcccaattg
     1861 atttcgcatt gatttgaaca ctggtcaagc caggggagag gtttgcgatt gtctcgatat
     1921 tatcaaagct tgctacaaca atctcttctc caatttggat atttttttgt ttcaatgccc
     1981 gatagacacc aattgccatt ggatcgctcc cgacaagaat ggcagtagga agaggggatt
     2041 cattttctaa tagattagtc gcaagtacct caccttgttt ttctgtccag ccacctagat
     2101 gataagacat atatttttct aagtgatgat cgatcataaa atgctgatag gcacgcatcc
     2161 tcttttcatt tatagaaatc tgcttcccac cgaattcatc catatcgact ttatatcccc
     2221 cgatataggc tattctttta tgaccatttt ctaagaacaa ttccagtacg gttttagtca
     2281 tccgttcaag atctgcatac accatatcga cctcttgctg gatgtcaggg ttatccacga
     2341 cgactatttg catgttttgt tttaacaagg cggtaatcga ttctttcgta acagtcccaa
     2401 caacgatcac cgcacctaac tgatctagat cttcccattg tttaggatta tcagatagat
     2461 tatagattcg attcatccct aaatgcagac gtcgagcttc ttcttccatc cctactcgca
     2521 aatgtttgta atagatatcc tgttcttcgc tcgctttgcc gatcgtagag atcacaccaa
     2581 tcgaaggcat tctctttttg atatatttac gagtactgat gtcataatcc aacgcagcag
     2641 ctgcctctac tatccgttgc cgagtagtct gagccacatg gatcgtctga tcgttattca
     2701 acacacggga aactgtagca ggagagacat ttgcctttcg tgcgacatct ctaattccaa
     2761 ccatttttac acactcctca aaaaaataaa aaatttttat tgacaaaatt gtttagtaaa
     2821 cagtatacag gaattataaa aaaaagtaaa cggtttccgt tttgttggga gtgaaatgat
     2881 ggatattacg catagaaaaa cagataaaaa tttcatctta tttgatgaaa agagccgagt
     2941 cttccattta cgaaatacat ttctttctta tctgataaag atagaagaaa gcaatgtatt
     3001 ggcgcatatt tattttggca aaccagtcaa gcagtacaaa gacaataaaa attatccccg
     3061 aagagatcgt ggattttcag gaaatgttcc cttaaatcct gaccggtctc tgtcgaaaga
     3121 tacactaccg caagaatact cttctcatgg cagcatggac tttcgaacgc ccgcatcgat
     3181 cattcagcgc aagaatggat cagacttact ggatctgaga tatgacagcc attatattac
     3241 agatgggaag ccagagatcg aaggcttgcc tcaaacttat gtgatggaca agtcagaggc
     3301 acaaacgttg gtgatttcac ttaaggatag agaaacagcg atttatttcg atttgttcta
     3361 taccatattt actgatagag cagtgatcac acgatctgta aagataagaa atgaaaccgg
     3421 agaaacaatc aaactagaaa aagcggctag tttccagcta gactttgccc atactaggcg
     3481 atttgatgaa gtcattgctt tgccaggagc acatgtcaat gaaagacaga tttcacggca
     3541 atctgtttta tctggaacaa aagtatttga aagccgtcga ggaacgagca gtcaccatat
     3601 gaataacttt attgctttag ttcatcatca tacgacagaa aatactggag aagcgatcgg
     3661 acttcaattt gtttattccg gcaaccattc tttcgaactt gaaaaagatc agatcaatca
     3721 attgagagtc gtcggtggga tcaacagcca tcgtttttcg tgggaattga atgcaggcca
     3781 gtcttttcaa acacctgaaa tgatcctttc ttactcaagt cagggattga acaaaatgag
     3841 tcagatccac catgagttgc tacgtgaaag aatcgcaaga ggtcgtcatc aatttgctga
     3901 acggccgatt ctggtcaata actgggaagc cacttacttt gacttcaata gtgaaaaaat
     3961 caaggcgatc attgatgaag caaaggagct aggcatcgaa atgttcgtat tagatgatgg
     4021 ctggtttgga aaaagagatg cggacaattc ttcattagga gactggttcg agtatgaagg
     4081 caagttgaca aatggattac gtgaaatagc agattatgct catagcaaag gattgaaatt
     4141 tggtttatgg tttgaacctg aaatgatctc ggttgattct gaactgtatc gaacacatcc
     4201 tgattttctt atgcaggagc caggtagaat gccttctgct tccagatcac aacatgtact
     4261 ggattttaca aggttagatg ttcggcagac gattgagaaa caaatgagaa agattttaga
     4321 tacgattcct cttgactaca tcaaatggga tatgaaccgt tcgctttcag atgtctattc
     4381 gattaccctt gacccacaga gacaaggaga agtagcgcat cgttatatgc tcgggcttta
     4441 tgaactactt gaacatttga caactgatta tccggaaatc ttatgggaag gctgttctgg
     4501 tggaggtgga cggtttgatg ccgggtttat ttattatatg ccgcagtcat ggacaagtga
     4561 taacacggat gcagtggagc gtatgaaaat ccaatatgga acaagccttg cttatccgat
     4621 ttcgtccatc acagctcatg tatcagctgt accaaatcat cagaccgaca gatctacttc
     4681 gttgaaaaca agaggagaaa cagctatgag cgctgttttt ggttatgaac tggatttgac
     4741 aaagctgtct cctgaagaaa aaaagcaagt aaaagaccaa attatatcct atcaaacgat
     4801 tcgtccggtg atccagtatg gccattatta tcgtttggcg agtccttttg aagaaaatat
     4861 tgccgcatgg atgtttgtgt ctcctaaaca agatgaagct attgtgtttt tagggaggat
     4921 actagcttca gctcaaccag cgttccatga agtatatctg atggggttag atgatgaggc
     4981 actttatcag gaacagacct cgaagcggat attttcgggg gccgaattga tgacagttgg
     5041 actttacttc cccgattttc aaggtgattt ccaaacagaa ctgcttcatt tcaaaaagtt
     5101 atgagagaga aggaaaaaag tatgaaagca aatataaaat ggttagatga tccacaagtt
     5161 tttagagtga accaatcaaa tgcacatagc gatcatgttt gttatgcaac aagggaagaa
     5221 gtagaaacca catcctccct taaacagtct ttaaatggat catggcgttt ttgttattcg
     5281 ccaaatcctt cggtacgacc aaaaacattt tataaaaaag attttgatgc ctgttctttt
     5341 gatgaaatca ctgttcctag tcatattgaa ttagcaaatt atgacaagat ccattacatc
     5401 aatacgatgt atccgtggga gggacatgta tttcgccgtc cccctttcac gacaagccct
     5461 gagaaagagg cggaagggat cttttcagct gctaaagaca atccggttgg ttcgtatttg
     5521 acgacttttc gattagaaga aggtctaaag ggaaaacaaa tctcgattca ttttgctggt
     5581 gtagaacaag caatgtttat ttggttgaat ggtcatttta tcgggtatgc cgaagattcg
     5641 ttcactccgt ctgaatttga tttaacacct tatttggaag aagaaaatat tctagctgtg
     5701 gaggtttaca aaagaagtac agctgcattc ttggaagatc aggacttttt ccgatttttt
     5761 gggatcttca gagatgtctt cttagttgct cgaggacaaa accatttaga agatctttgg
     5821 atcaaacctc gcttagatga caaatgtcaa aatggcaaac ttgaagtaga tttgtctttt
     5881 gagcaagtag ccaaaaacag tcagctgaat gtagcgatac tagatcctga tgggaaggaa
     5941 atctatcaac agcaatatcc gttaaaagag caaatgacga ttcgcatcga tggatttgaa
     6001 aatgtggcac tgtgggggca ttttcagccc aatttatata agcttgaatt ggagacgata
     6061 gacgaagaaa aaagagtaac ggagtatatt gactattcct tcggttttcg taaaatcgaa
     6121 atcaaagata aaatcatcta cttcaatgga aaacggatga ttatcaacgg ggtaaatcga
     6181 catgagtggc atccgaaaaa aggacgcgcc atcactatag aagatatgga aaaagatttg
     6241 gctatcataa aaaatgcaaa gatcaacggc gtacggacat ctcattaccc caaccagatc
     6301 acttggtatt atttatgcga ccaagcagga atccatgtga tggcggaaac gaacctcgaa
     6361 tcccatggct catggcaaaa aatgggcgca tttgagcctt cttacaacgt accaggtgca
     6421 gtacctcagt ggcaggcggc tgttcttgat cgagcaaaaa cgaatttcga aacattaaaa
     6481 aaccatccaa gtattctttt ttggtctctt ggaaatgaat cttatgcgga agaaaacatt
     6541 cgacaaatga acgattactt caaaaaagta gaccccgatc gacttgtcca ttatgaaggg
     6601 aattttccaa atccagcatt cgaagattcg atttcagatg taaaaagctg catgtatgcg
     6661 ccaccagaag agatcattga ctaccttgaa aataaagcgg aaaaaccgtt catcttatgt
     6721 gaatatatgc atgacatggg gaattcgtta ggtggaatgg attcttacat gacgttgctt
     6781 gatcgttatg aaatgtacca aggaggctat atatgggatt ttaaagatca ggcgatccaa
     6841 gtgactgatc caatcacagg cagagaagtg atgcgctatg gcggtgactt tgacgataaa
     6901 ccaagtgact atgaattctc agggaatggg atcgtttttg cagatggaca agaaaaaccc
     6961 gccatgcagg aggtaagata ttattatgaa aaatacagta aataaaagtc atatggatac
     7021 ggaaaaagtt gcaatcgtct tcggcgactg tacattaggt gtcaaatcgg ggaatacgca
     7081 ttatattttt tcttatacaa gaggcggact ggaatcgctc aataaaaacg gaaaagaatg
     7141 gctataccgg gaaacacttc cagttttttg gcgagcaacg accgataatg acagaggtag
     7201 cggatttgga tttaaatccg gtatgtggtt aggagccgga ttgtatccaa aagtcaaaga
     7261 aatagaagta ctggtggaca ataaaaagat cgatttgccg attgctccag taaataatca
     7321 atattcaagt aatgaatacg ctgaaacggt tgaaatcatt tttacactgg aaatcaacac
     7381 agtaccaaaa acccaagtga caatttccta ccaaatcgct ggagagggta aaatgcttgt
     7441 caatatgcat tattatggac aaaaaggatt accggaatta cccgcattgg gtttaaggtt
     7501 cattatgcca acgaaagcaa aattttttga gtatgaaggc ctatcagggg aaacatatcc
     7561 ggatcggatg gctggtggtg tcgaaggtat ttataaagtg gcaggactcc ccgtttcccc
     7621 ataccttgtt ccccaagaat gcggcatgca tatggaaacg aaatgggtag aactaacaag
     7681 aaatcaaacg ttggataata cggataaaga tcaagaagat ttttcgttgc gatttgaaca
     7741 gcaggatacg ccatttgctt tttccgcttt accattcaaa gcagaagaac tggaacaggc
     7801 aacacatata gaagaactac cgccagaaag acgaacggtt cttacgattt ttgcaaaagt
     7861 aagaggagtc gggggtatca atagctgggg agcggatgtt gagtcacctt accgaatcag
     7921 cagcgaagag gaccatgaaa tcggctttat tattcagtag caatctttag attattattt
     7981 gaaaaacgga gtttacaaga caaagctgct ttattctata tgtcatgaac aagagagtaa
     8041 aaaagttctc agatactttt gttcatgact attttcttca ataaaaccaa ttgttatttt
     8101 tctgaaaaac aaagttaact atcagaaaat taaaaaaagt
//
LOCUS       DARBDN010000105         8024 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000105 DARBDN010000000
VERSION     DARBDN010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.108"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            197..898
                     /locus_tag="SCH06_002394"
     CDS             197..898
                     /locus_tag="SCH06_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEG1078927.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1507..2523)
                     /gene="tsaD"
                     /locus_tag="SCH06_002395"
     CDS             complement(1507..2523)
                     /gene="tsaD"
                     /locus_tag="SCH06_002395"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEG1078928.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2520..2984)
                     /gene="rimI"
                     /locus_tag="SCH06_002396"
     CDS             complement(2520..2984)
                     /gene="rimI"
                     /locus_tag="SCH06_002396"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEG1078929.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2991..3533)
                     /gene="rimI"
                     /locus_tag="SCH06_002397"
     CDS             complement(2991..3533)
                     /gene="rimI"
                     /locus_tag="SCH06_002397"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEG1078930.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3517..4239)
                     /gene="tsaB"
                     /locus_tag="SCH06_002398"
     CDS             complement(3517..4239)
                     /gene="tsaB"
                     /locus_tag="SCH06_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEG1078931.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4430..5410)
                     /locus_tag="SCH06_002399"
     CDS             complement(4430..5410)
                     /locus_tag="SCH06_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1078932.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5434..6918)
                     /gene="galT"
                     /locus_tag="SCH06_002400"
     CDS             complement(5434..6918)
                     /gene="galT"
                     /locus_tag="SCH06_002400"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEG1078933.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6930..7919)
                     /gene="galE"
                     /locus_tag="SCH06_002401"
     CDS             complement(6930..7919)
                     /gene="galE"
                     /locus_tag="SCH06_002401"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEG1078934.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2266 a         1713 c         1408 g         2637 t
ORIGIN      
        1 tattattgtt gttttttata cacaaatcat tcgcttcaaa acaaattatt caataccatt
       61 gtatattttt tacataataa caaattatat ttgtaaagta ttaaaacttg tttctaatgt
      121 tggtatgtta aaactttaca aattctttaa aaaaagtgac aataaatata gtgaacaata
      181 aggagaggac tttttaatgc gtgttaataa aatcgatttt cacttttcaa aactcagata
      241 tcaacctgat tttgaacatt tctcggatga agagttccaa cagatcaagg aacatactgt
      301 tcttcgttct tataaaaaag gacagatcct tttcgacgat ggtgatccca gacaacggtt
      361 gtatatcttg accaaaggac tcgttcgttt agaacgttat gatgaaagtg caacttatta
      421 ctactatgac tatgtgaata caaataacct ttttcctatg tcaggaatgt ttggagaaga
      481 gacctacact tatacagctc aagcgatgac tgatattgaa acattctacc ttcctgtttc
      541 ctactatgaa aaattagcac gaaaaaatcc cgaacagttg atctatatga tacaaaaaat
      601 ttctaaagta gttgaaatac atgaattgcg tatccaaatc ggattgacct ctagcgcctt
      661 tgaccgggta aaacaaaatt tattcatttt gaaagaagaa ttgggcgtac caacaaaaga
      721 tggtcatatc accattcctt atccgatcac cttaaaagaa ttagcagtga atagcggcac
      781 gacacgtgaa actgctggac aagtaatcaa acaactacgt gattccgggc tgttagatta
      841 tgacaaaaag cgttttactt tctgtaagac agctactact ccagctatga gagaataacg
      901 cgaacaaaaa taagcagtga ccctgataaa tatcagggtc actgcttatt ttcctcccta
      961 aaacttctga aagatccggc agttttagat cactggacaa gactcaaaga ttttctatgt
     1021 gtgtttcagt tatgtaatat tcactgtttg caaaaaatac tgttagatta actagatgaa
     1081 gcgtcttgtc ctcatccgat ctagattatt cgatattcct cgacaataaa cgattactca
     1141 gtgagggcaa tcagaggaac ggataatgat aaataagctg taaaaaatag caaaataaca
     1201 ataatgatta aaagtatgta aaaaataggg ctttgacaaa aacgtgtcac agccctattt
     1261 cgattaaacg gtgtgtacct gtcaactctt cggtcacaag tcataatgtt cataaacatg
     1321 aggagctgtt ttttgaaatt gttccttgtg aatcagagtt aaacgacagg cttacgaact
     1381 cttgattaaa cggcgttcaa aagcttgcat acgcggtaat aagaacagcc aggtcaaaaa
     1441 catgagaagc cgtttttcct gggctgttct tattacttga tgcagggcag ctttttcaca
     1501 acctctttat tcagataaaa ccaagcttgg atcagcattc aactgatagc tagcaaaatt
     1561 tcttttttgc atttccacat gtgctgctgc tccaatcatt gcagcattat ctccacaaag
     1621 tcgaagaggg ggaatcacta gttctacctc agggagttta gctgccaaag catcctgcaa
     1681 tccttcacgc aacccttgat tggccgctac acctccagct ataatcagtt gcttgactgg
     1741 ataattttga caagctcgaa gtgttttagt aatcaataca tcgatcacac ttgcttgaaa
     1801 gctagctgct aaatcatttt tgtctagatc ttctccacgc tgttgtgcat tatgcaccaa
     1861 attgataaat gcacttttta atccgctaaa actgaaatca taattatctt catggatcat
     1921 cgctcgcgga aaatggtaat tatcttttcc ctgatgagct agctgatcga tttcttttcc
     1981 gcttgggtaa gaaagaccta atactcttcc aactttgtca taagcttctc ctgctgcgtc
     2041 atctcttgtc tccccaatga tttcatatga tccatcttct tgcatataga ctaattctgt
     2101 atgtcctccg ctaacaagaa gtgccatcaa tggaaactgg aatggtttaa ccagacgggc
     2161 tgcatagata tgccctgcca tatggtttac aggaataagc ggcaattggt gtgcccaagc
     2221 aaaagcctta gctgcagaaa taccaatcag caacgagccg acaagtcctg gtccataagt
     2281 gacagcgact gccgataaat cttctgccga cacaccagct tctaccagtg catcttccaa
     2341 gcataaggtg atttgttcta cgtgatggcg gctagctact tcaggtacta cgccaccaaa
     2401 acgtttatga ctgtttattt gagaagcaac gatgttagat aagatctctg ttccatttct
     2461 aacgaccgct acactcgttt catcacaact tgattcaatc gccagaatca attcttcatt
     2521 catttcatcg tctccgtttt taactttctg ctcataatga tcgcatcttc cgtcggattg
     2581 cgataatatg atttccgttt acctaatata cgaaactttt ctgattcata aagttttctt
     2641 gctgcttcat tagatagacg tacttctaaa aaaacatgca gcgaatcttt tatttgttcc
     2701 gtaatcagta attgtaacaa atgccgtgca tgcccttttc cttgttctga aactgcaaca
     2761 gcaatatttg tgatctcgac ttcatctatt actttcgagt atccaataaa gccacagatc
     2821 tggttatctt cagctaaaag cagataatca gagtgaggct gttggatgtc tgccaaaaac
     2881 tgcattttcg tccaaggtga accatgtgga taagcatttt cgctaatcat ccatacgcat
     2941 tctgccaagt acgcttcatc aaaatctttt tttctgcaaa tcaactaatc tcactcattt
     3001 tctaaaagtt ttatcatatc caacgcatct tcttttgttt cagtgtaata tctttttttg
     3061 atcgttgttg cttgaaaccc caatttccga taaagtcttt gtgcatcttg attactcata
     3121 cgcacttcta atgacatcgt ctcacagcga ttcattatag caaagttctc gatttcgtca
     3181 ataagcagcg aaccgattcg tttacgctga tatgccggtc gaacggcaat attcgtgata
     3241 tggcaatcta aaccgaacgc tcttgaaccg ataaaaccaa tcattcttcc attatcaaag
     3301 atacctagat atagatgagg aagcggtgac ttcaattctg atataaaggc actttttgtc
     3361 catggcaatt cgccattata gacttctcgt tcgacatcca gcagctcttt gatatcttct
     3421 gtagtcaatt ctcttagtac gtaacgacga tcgatttgtt cgactgtttt ttctgtataa
     3481 atcattttat cttgaaaaaa gcttctggca tacgctctaa attttttcaa cataactttc
     3541 gtctccaggt gtgtgcgtct ccaaccattt ttcttctgct tctactcgtt ttaaatagcg
     3601 aggaagaaaa gcttgtttct ctgcaactgg ttcaactaaa gcacctaatt gagccacagt
     3661 tacaccactt ggaatatccc atgctggaac tgtattaatc atcgcactag gcaatatttc
     3721 ctttatttca gagaagaatt tgtgacaatc actcccgacg aaataaatag cttcattcag
     3781 cttttgtagt tgtgtgaaca aatcagaagc agaaatatgt acatcttcaa gtacagtttc
     3841 taatctattt tctttccagc ggtatgcccc agcgtataca ttttttcttc gagcatcaaa
     3901 catgggcaca ataatattat ccacaccgat gcaattagcc gcgatggttt tcagactaga
     3961 tactcctact agctctttat ctaatgtata agcaatcgtt tttgctgtcg ttacacctat
     4021 acgaagccct gtataagaac cgggaccatc agaaaccgcg attcggtcaa tgtcttttgg
     4081 acttatttga agatctgcaa acaattggtc gattgcaggc atcagtgtta cactgtggtt
     4141 gcgtttgata tttgtttgta tttgtccaag aatttgttcg tcttctacca caccgatcgc
     4201 caaagtttgg tttgcagtat ctattcctaa tgtaatcata tatttgatcc tttctgctat
     4261 gacattctcg ccttccattg tagcatactt ttttattctg aggatgaaaa taccaaaggc
     4321 aaaactagta caataataca tgattatctg ctggcgggca aattttgccc cttcctgaaa
     4381 cacaaaaaag ctgcggtatc actccatttt cccacagctt ttccatcttt tatttcgttg
     4441 attctcgaat aatcaactct gtttccacaa taatctttct tgaaaccggt gctttggaat
     4501 tacttaattg aagaatcgtc tccactgcta gctctcccat ccattcggta taaactttta
     4561 cagtagaaag cgagggcgtt acatatttcg ctacactgac atcattgaag cccatcacag
     4621 aaatatcttc tggtaccact aaaccttttt cttgaatcgc tttcagtgcg ccaatcgcta
     4681 atgcatcatt agctgcaaaa agcgcatcag gaacatgcgg attcgttttt aaatattgct
     4741 tcactgcttg atatcctgac tcgacagaaa aatctgcttc gataattgga ccttcgtcgt
     4801 agcctttttc tgccaaaact tgttgaaatg ccataattct gggatctttt agccgctgat
     4861 ggtttttctt cgtatattct gttccagcaa gcatagcgat atgttgcgct ttatgggaga
     4921 caaagtgttc aatgactttt tgaacacttg acttaaagtc gacaactaga gagtcgattc
     4981 cttgagaagt gccgtcagaa tctaccaaaa gcaaggcatt ttgggatcct ttcatttcta
     5041 ataactgagc ttcgtcgaat tttcctagtg cgatcgttcc atctgccgga agatcactaa
     5101 tggaatccca cgtttctttc aataaagtaa cgtttgcttc ttctgccttt ttttcgattc
     5161 ctaggcgaat agataaataa taaagatctt caagctcttc cgtatcgtcg taccactgga
     5221 tcaggcgaag cgtttgctta gtatttgctg catttttacg atgtttcgta taatttaagc
     5281 gttctgctgc ttcaaaaatt ttttgctttg tggctaagcc aacggaaaga tcaggatcat
     5341 agttgagaac tcttgaaaca gtagcaggag aaactcctgc caactgcgca atgtctttaa
     5401 ttgttgccat ttgtctctcc tcctttttta cgtttataaa atcgcagtaa atcgttcaaa
     5461 cgctgcctgt cctttttcat ctcgcttgaa tactccagcg tcttccagta cacgtgcaaa
     5521 aacctgacct acagattttt gtacgacatc ggtgaccgta tctttcgtca aatcaggatg
     5581 ttcttttttt aattgttctg cccacggacg atgatattca gccatctggt tttcttctcc
     5641 taataagaaa tgctctactt ctactagttc tggtttcaaa cgaggtggta aaacagcaag
     5701 ccccattact tcgatcaacc caatgttctc ctttttgata tgttggacat ctttatgtgg
     5761 atgaaaaatc ccatcaggat gttcttctga aacattgttg tctcgaagga caaggtccaa
     5821 ctcaaagtaa ttgtcccttc ttcgtgcaat tggcgtaatc gtatggtgtg gtgtaccatc
     5881 tgctgaaaaa gctctgatag atactgtttc atccgaatat gctttccatt tttccaatac
     5941 tgagttagct gcttcaataa gcaagttttt ctctgttgat tgcaaacgga tcacagacat
     6001 cggccatttc acgactcctg cgatgacttg cggataatct tctagtttga taagtttttc
     6061 tatcggtgct tttgccatag gaaattcatg acgtcctgcc tgataatgat catgagaaag
     6121 aatcgatcct ccaacaattg gtaagtcagc attcgaacca acaaagtaat gaggcaagac
     6181 ttcagtaatc cgaagcagtc tagcaaatgt ttcctttgtg attttcatcg ggcggtgttg
     6241 ttctgataaa atgatcgaat gttcattgta ataagcataa ggggaatatt ggaatcccca
     6301 gctttcaccg tctagattca ttcgaataat ccggtgattg gtgcgggctg gatagttcaa
     6361 gcgacctcta tatccttcgt tttccatgca aagcatgcag gtaggatagt ctacttttac
     6421 cgcctcgcgt tctgctgcga tttgttttgg atctttttct ggcttagata aattgattgt
     6481 gatttccagt tcaccatact ccgactctgc cggaaatttg atgttttttg cgatggctct
     6541 tgttttgatg tagtcatttt tcttacttaa attaaagaaa tactcagttg cttcctctgg
     6601 gcttttcgaa tagtgctgtg caaagaatgc attgacgact gaaggtggcg gtgtgagaaa
     6661 atccattaat tgcgcttcaa aaatctcttg ttctgctggc aattctgaaa gaacaccatt
     6721 ttctcttgcc ttagcgacaa gctgatccaa taagtctaca gattcttcct taactggtct
     6781 tacttcaatg ctttctagag catcttctcc taccatccct aaaagacgat tctgtaaata
     6841 taagcggtcc atttccatcc atccgccagc ttcgatcgca agtgtggcaa aatcacaaat
     6901 cgtttgactg attgacatat ctcattcccc tattcttcat aaccatttgg atggctgaca
     6961 tgccaatccc atgctgtttt gataatcgct ttgatatctg tgtattcagg tttccagccc
     7021 agaatctctc tcgctttttc acttgaagcg actaatcggc taggatctcc agctcttctt
     7081 ggtgctattt ctgctggaat ttcttttcct gtcacttctc tagctgcttc tagcatttcc
     7141 ttgactgagt atcctttgct gctgcctaaa ttgaagaagt tgctttcatt tccttctttc
     7201 aagtattcca aagctaaaat atgtgcagca atcaaatctt ctacttgaac ataatctctg
     7261 atacatgttc catctggtgt atcataatcg tctccataaa cagccaaggc ttttctttga
     7321 ccaagagcta cttgtaaaat gattgggaca agatgcgttt ctggtgtatg atcttctccg
     7381 atagatgcat ctgcttttgc tccggctaca ttgaagtagc gcaaagcgac atagcgcatg
     7441 ccatatgctt ggtcacacca cttcatcatt ttttccatca tcaatttact ttcaccatac
     7501 ggatttttag gattagctgg tgtatcttct gtgattggag actctttcgg ctctccataa
     7561 gttgctgcag tagaagagaa tacgatttta ttcacgttga actcgtgcat gacttcaagt
     7621 aagatttgca taccgtatac gttgttgttg aaatacatca atggtttttc gacagattct
     7681 cctactaaag agcttgcagc aaaatggatt actccttcaa tcggttcctt ttcaaatacg
     7741 gaacgtagaa attctttatc ccggatgtct ccttcataaa aatgagcatc tggatgtact
     7801 gcttgtttgt gacctgtgag caaattatct accacagcta cttgataccc cttttgaact
     7861 agctggtcta cagcgtgcga accgatataa ccggctccgc ctagtactaa aattgtcata
     7921 aaaaacactc ctttgattag taaaattgtg tttgttgatt ctatataatt taaaaaacga
     7981 agtttacttt tatggtgaaa acaaacaaag taaaatttcg taaa
//
LOCUS       DARBDN010000106         7865 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000106 DARBDN010000000
VERSION     DARBDN010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.109"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(22..996)
                     /locus_tag="SCH06_002402"
     CDS             complement(22..996)
                     /locus_tag="SCH06_002402"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEG1078935.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(1076..1951)
                     /locus_tag="SCH06_002403"
     CDS             complement(1076..1951)
                     /locus_tag="SCH06_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HEG1078936.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            2081..3988
                     /locus_tag="SCH06_002404"
     CDS             2081..3988
                     /locus_tag="SCH06_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HEG1078937.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(4529..7807)
                     /locus_tag="SCH06_002405"
     CDS             complement(4529..7807)
                     /locus_tag="SCH06_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HEG1078938.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLESYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT         2217 a         1662 c         1462 g         2524 t
ORIGIN      
        1 ttctttccct cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact
       61 catcggtgta ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac
      121 gattgttaag ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat
      181 atctttgatt ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga
      241 cgcacaggca tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag
      301 cgttgctcct gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc
      361 gatcacataa ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct
      421 gttcaaatat tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac
      481 tacgatgtca tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt
      541 aaataaatta tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa
      601 agtcagtact cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat
      661 cggttcatga ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac
      721 attgatcgtt ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata
      781 gtagtcattg acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact
      841 ttcttcgata ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa
      901 ttctgttccg aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa
      961 aatcttcaac gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta
     1021 ttcttcgata gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag
     1081 gaagtgaaac tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt
     1141 tgtcgtgtac tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca
     1201 cccaatgatt gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc
     1261 cttcacgtat acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct
     1321 catgattgcc attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg
     1381 taggaagtcc tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag
     1441 ccgtattttt cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat
     1501 aggcaaggag aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt
     1561 tcttatacct caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc
     1621 ctgacctttt ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata
     1681 actcgattgg ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag
     1741 tatattttgc tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt
     1801 gatcttcaaa aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag
     1861 tgctggctaa ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt
     1921 gattcagttg ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc
     1981 agtttgattg ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta
     2041 agataatggg cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa
     2101 acaagatttc tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga
     2161 taaaccagct acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg
     2221 agaaacagac gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt
     2281 ccttgcatat tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc
     2341 gcttcaacct ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca
     2401 atttccagaa tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga
     2461 tatgaagaat gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga
     2521 taagacgtat tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga
     2581 tatggctgtt cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac
     2641 ggaacaagca gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa
     2701 cgcagattac agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga
     2761 taaactggac ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat
     2821 cgtaactgat ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc
     2881 gttattcaaa agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga
     2941 agaattccgc caagtcagcg gaatctattc tcgcgtattg tctggaacag acgaagcaat
     3001 gcctcagaaa aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga
     3061 ttactacgga aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa
     3121 aaaaatgatc gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac
     3181 aaaagaaaaa gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa
     3241 gatcccagca ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct
     3301 ttcaaatact cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa
     3361 accagtggat cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc
     3421 atttcggaat gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga
     3481 acaatcaagc tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca
     3541 tgcatttgat aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac
     3601 agaagaagat cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg
     3661 tctgcctttt gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga
     3721 tgcaggcggt ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga
     3781 ggaattcttt gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca
     3841 acttttactg caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa
     3901 aaaccttgac gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc
     3961 gccagaaaaa agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa
     4021 ataagaagga atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc
     4081 gaagaagtta cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa
     4141 gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta
     4201 ccgagaaact ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct
     4261 gagtattaga gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat
     4321 accgagggtc agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca
     4381 tcaagtaata agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag
     4441 aaggaagtga gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg
     4501 ttttacatca taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa
     4561 ctacaccgat taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg
     4621 tttttgggag tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag
     4681 aaggttttcc atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt
     4741 tgtcatttcc cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa
     4801 cagattctgt atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt
     4861 ctagcgtata ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag
     4921 cacttgactg tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga
     4981 caggcgttcc ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa
     5041 tgatatttcc ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat
     5101 tttgttcatt tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg
     5161 aagacggtga ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc
     5221 tttccttttc tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac
     5281 ttccattttc atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact
     5341 cgatccaatc ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat
     5401 tccaatagta gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct
     5461 gctctctcat ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg
     5521 tgtttcctgc tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac
     5581 tgctattgac gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga
     5641 aagacaaact attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc
     5701 cattaccgtt accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt
     5761 ttttgatgat tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt
     5821 catctgcatt atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt
     5881 tggccgcaaa tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt
     5941 tcttgactaa gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt
     6001 ggattcctgt atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag
     6061 aaatctgtaa tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc
     6121 agtagtgact gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct
     6181 tgttttctgg atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc
     6241 cttttggaat cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct
     6301 gcccagcata tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt
     6361 ttcctgcatc tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt
     6421 ccactgtatg aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg
     6481 gatagttttt atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg
     6541 tctgataatc aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct
     6601 ctcctgttgc tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag
     6661 tatgatcttg gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc
     6721 gagtaggtct ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc
     6781 cttctacctt gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat
     6841 ctgaagcgta taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt
     6901 caggatcgta ataatatgac tctaaaccag tattcgtttt tttcatctct acgtccagtt
     6961 tagtaatcga gttcgtggcc ggaaacaaat tcccatgacc gtttccgaat atattataag
     7021 aacctgtttc tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga
     7081 cactcccagg agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg
     7141 tccccaatcc aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat
     7201 ccgagtccca gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg
     7261 cctgcccaaa caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt
     7321 gggcattcgt ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt
     7381 ctttggggat tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc
     7441 cgccgttatt cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac
     7501 tagcacttgt gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt
     7561 gcttttttgt cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat
     7621 ccatatcttc actagttctt ggtacttcct ccattgttga catcccttca atgttcacgt
     7681 gtgcattttc ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta
     7741 aaaccggggt actgagcata aggagattca tcattagcgc actgtatttt atacgttttt
     7801 ttaacaagtg tattcctccc gtaacaaatt agaaagcgtt tacttaaagt attacctaat
     7861 ttatt
//
LOCUS       DARBDN010000107         7828 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000107 DARBDN010000000
VERSION     DARBDN010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.110"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..384
                     /locus_tag="SCH06_002406"
     CDS             <1..384
                     /locus_tag="SCH06_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078939.1"
                     /translation="LNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLL
                     FTRIYIFLMSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGI
                     LEGIIFYIGYFPNKNNNFYFYRNKL"
     gene            complement(510..1187)
                     /gene="nth"
                     /locus_tag="SCH06_002407"
     CDS             complement(510..1187)
                     /gene="nth"
                     /locus_tag="SCH06_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEG1078940.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1194..1892)
                     /locus_tag="SCH06_002408"
     CDS             complement(1194..1892)
                     /locus_tag="SCH06_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEG1078941.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2160..3344
                     /locus_tag="SCH06_002409"
     CDS             2160..3344
                     /locus_tag="SCH06_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HEG1078942.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3350..3793)
                     /locus_tag="SCH06_002410"
     CDS             complement(3350..3793)
                     /locus_tag="SCH06_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEG1078943.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(4019..4306)
                     /locus_tag="SCH06_002411"
     CDS             complement(4019..4306)
                     /locus_tag="SCH06_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078944.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4477..5829)
                     /locus_tag="SCH06_002412"
     CDS             complement(4477..5829)
                     /locus_tag="SCH06_002412"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HEG1078945.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            complement(6102..6548)
                     /locus_tag="SCH06_002413"
     CDS             complement(6102..6548)
                     /locus_tag="SCH06_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEG1078946.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6784..7710)
                     /gene="cysK"
                     /locus_tag="SCH06_002414"
     CDS             complement(6784..7710)
                     /gene="cysK"
                     /locus_tag="SCH06_002414"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEG1078947.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
BASE COUNT         2118 a         1590 c         1272 g         2848 t
ORIGIN      
        1 ttaaataaat ttactttaat tgctcctatc cttgcattta ttattttttc tgtactttta
       61 agcactactc ttaaaggaaa atttatggaa agaagctctc atgcaatgat tctcactttt
      121 ttatggttgt tgttcaccag aatctatatt tttctgatga gcctgaaacc gcccaaatcc
      181 attagtttat gtttagttat aaatggtatt tttttattat cacttatcat ttttattaca
      241 cctttagata gatacgtcac ttatttatat aatcctttgg aatactggac ttattttata
      301 ggtatattgg aaggcattat tttctacatc gggtattttc ccaataaaaa taacaacttt
      361 tatttttatc gcaataaatt gtaataagtt accatcctag ctactgagta tgtacattta
      421 ctttttcatg caaaaaagat aaacgaaaca gcttttctcc ataataacaa gataattcat
      481 acatttattt gcaattaaag aaaccacgtc tacaggcgtg gtttcttttt tagcgccttt
      541 tcttttagac gcatccgatt tttcccatct tgacatattg atagcaaagg acatacctcg
      601 cacttgggat ttcttgccgt gcaatgatat ctaccaaaaa aaatcagtgt atgatgtgtc
      661 tttacccata attcttgtgg tactttccgc atcagtgttt cttctacttc catgaccgta
      721 gcatctagtt tgcagatcct caggcgtttt gagacacgtt ccacgtgggt atctactgcg
      781 attgctggta tcccgaatgc atcccccaat acgacatttg ctgtctttct gcctacacca
      841 ggaagagaca tcaattcttc tcttgacgtt ggcacttgcc catcgaaacg ttcaatcagc
      901 tgctgtgcac acgctttgat gttttttgct ttatttcgat acaaaccaat cgtttttatt
      961 ttaagaatga tttcatcgat tgaagcttct gctaacgcat cgggtgtcgg aaaagaggca
     1021 aacaaatctg gcgttgcttt attcactgat acatctgtcg cctgggcact taagatcact
     1081 gcaatcaata actcaaatgg attattgtgc ttgagttctc catgtgcttc gggaaacatt
     1141 ccatacatcg tttctagagc ttccattgtt ttttgtttgc ttaacatatt ccgctactcc
     1201 tccaaccaat ttttcagtga gactttcggc aattcttctt gttgagctga ctgttctact
     1261 tctctttgaa gaagctgctg ttttcttcgt ttttggtctt cttccacttg ttgttttgta
     1321 cgtagatttt ttctttccca cgatagcaaa atgcggtcaa cgtaattaaa actataagcc
     1381 tgatttaata cggcttcccg cagtgctagc ttcaaaattt ccggctgata atggtcttct
     1441 tctagccatt gtccgatccg ctggaactcg atcgaagaaa gcgggcgtcc aaattcttgt
     1501 tcaaataatt gatacactga ctggatttct ttttcttgtg ttttttcttc gtattttttt
     1561 tcttgtgttt ttaaatactc acctaataga tcatagatgg ggtaaagatt atatcgatct
     1621 gcttttttac cgttgacaat cgtcgtttct atcttgataa atccatttgt tacgagacga
     1681 tccagtattt gaaaaatctg atcttgtttg attcccatat ccatagcaat catctgcaaa
     1741 tcagggaaag tatctccttc aagctgtgcc atatgcaact gtagaacaaa taaaaattct
     1801 tcagattgta gaccgatcct atgataattt ttaagtaaaa gattagatat gactgtttgt
     1861 ccagcgctta agtaattttc taaattcaac atgatttctc ctccgctcaa tcacagtata
     1921 cgtaaaaaaa acatgggaag caagaacagg tttcttttct atttacttca ctgatcggtc
     1981 agatttacaa tgtcgtctac ttgatttttg tttgttcatg tttttgatgc gtatcttcac
     2041 ttttcggaat aaataaatta agtagatttc gctgttcctt agaatgttga caaggaaaca
     2101 aaattactat acactatttt tgtttccaag ttaacattat tgcataaagg agtttttaca
     2161 tgtacagttt cacaaataaa cattctaaag tttttggata cgtctctgtc ttattcactg
     2221 gattaggatt tactatcgtc agtcctgtac ttccgttttt aacgctgcct tattctcact
     2281 ccatacatca gcaagctttc tatatcactt tgctcatgtc tgtttatgct ctagctgcct
     2341 tcttatctgc ccccattctc ggtagcttaa gtgatcattt tgggcgtcat ccgatcctta
     2401 ttatcagttt attaggatca agtatcggat atttgctttt tggtttagga aattcgatat
     2461 ggatgttgtt ccttggtcgt atcattgaag gattgacggc aggagaaatc tccaccttat
     2521 atgcttactt tgccgacatc acggaaccta atgaaagaac caaagttttt ggatggatgg
     2581 gtgctttagt cggtatagga acaacgctgg gtcctattat agggggtcta ttagctgagt
     2641 tggggaattc tgttcctata tttattggag cactctttac tttcttaaat gccgtttatg
     2701 gctacacatt tatgctagaa agccttccaa taaaaaaacg ttcagtagat ttaagtttct
     2761 cccatgtaag accttttcac caattacaac aattattcaa gatttcatcc gttattcctt
     2821 tattgacagc aggttttgct gtttggttgg cagctggctc tcttcaatct atcttttctc
     2881 aattttcgat tgacgccttt cagtggaagg ctgggttggt tggtttaagc ttctctttga
     2941 ttggaatctt ggatactgtc tcgcaattgt tcattatgcc tcgattgctc aaaaaatttt
     3001 cagaacagca gatcacaaga atagggatgt tcagtgaaat cctcgcctat ctattcatca
     3061 cattatctgg aattcttcta ctgccgattt tgtttttatt tgggattatc tgttatggtt
     3121 tcggtgattc tatttttact cctgtattca atggccaact atccaattct gtctcagata
     3181 accagcaagg tcttgtaatg ggcggtaccc aaagtataca atctctatcg cgcgtcatcg
     3241 gcccgctaat cgcaggacag ctttatgctg cagcaccatt tcttccgacg gtattcggat
     3301 ttttgcttat gatttttgcc tattatcact acaataaaaa atagtagctt catttgctac
     3361 ttcgtataaa ttctctgtat cgaccgataa aacgaaatac tgtgtcaaat tcttcttttg
     3421 acatattttc aaatacagta gcatctcgct gtacccattt ttgatggagt tgctcgtgtc
     3481 tattccttat tttttgtccg attggcgtca attgaaaata gatttctttt ttattctctt
     3541 cgctttgata agtgtttatg atccctctag ctatcagttt ttttgttagc ttactgatgg
     3601 ctcctctagt catgtaacta gcattcgcta attttgtcac gttaggatca gggattttcc
     3661 cgatatgttc aatcacttct agttcattta gagtaaatcc tgcaaattct ttttccattt
     3721 ctggtttatt acgatgaata atctcattag ctaaatccag atattcttct attagcagtt
     3781 gtcttttatc catttctaca ccttcttttt ctttcattat attgtttttt tgtttcctat
     3841 tcaacaaaga taaaaatatt ttgtaggaaa acccaatctg aaaccaagaa aaaaaggggt
     3901 tgacaaagct tgtcataacc cctttttctg attaaaagat agtaaagaga cagtcatcgg
     3961 taattgtgat gattttttgt catcacttaa ggatgagcgg ccttttcaaa aactgtcttt
     4021 aaagatcatc atcagtttct agcacatatg gctgaccttc atatgtgtac tctgtattca
     4081 atgtgccgtc attttcatct gagtagatgc gtctactgaa aggaaaacga tgagaaacat
     4141 tatctttggc gtcatttgct ggcatcgtgt aatattcctc ttgcgtttca ttcaactgag
     4201 agagtacttg atctgccaac tcatcaatat tgatcgttaa tttcttcgaa gcacttttat
     4261 aatcttctaa aaatgcatct tgttggacaa aatattcttt attcatcttc tttctcacct
     4321 ttcttttcaa aatcaaataa agctgcttgt tcttttatgt aacagcttta tctttgctgc
     4381 ttattgtgac aaaaaattcg aagaaagaca actaattgta cttttcacaa aaaaagacag
     4441 agggtcgtga caaaattgtg tcacaaccct ttttctttat tgtgcagttt cgatttcgcc
     4501 tagcgctgct tgtgcaagta ggttcaagta attccatggg cggtcaaaat gtggttggaa
     4561 gaagaaatct gaaagtgcga gatcttctac agtcatttta ttttgaacag ctaaagacat
     4621 ggtatttgct gattgtgtaa tgtcgtattt ggacatgaac tgagcaccta cgatacgatt
     4681 cgttcctttt tcatagacta gctccatcat tactttttca gtagttggca tgaactctgg
     4741 acgataatta tcttcaaata cagtcgcttg gacttctaga tcgttcaaag ttgcgctttc
     4801 tttggtcaca cctgtcgaac cgatcgtcca gccaaatagg taaagtcctg aagttccttg
     4861 agtaccacga tacgccattt tatgatctgt caagttattt cccacaagca aaccttgacg
     4921 aacggcattt gttgccaaag gaatatagtt ttgcgtgcca cttggattgt agttgactac
     4981 tgcagagtct ccagctgcaa aaatgtctgg attacttgtc tgcatgtatt cattcacttt
     5041 gattgccccg tttggcagtg tatctacttt tccttcgatc agttttgtat ttggacggaa
     5101 gcccacacat aaaatgacca tatctgtatc aaatgtatct gttggtgtag ctacttgttt
     5161 cacttttcct tcttcatctg tgataaattc agtaacattt tcgcctagcg caagagtaac
     5221 accgcggtct gtcaattctt tttctaagat atctgtgaat ggtttatcta gatatttatt
     5281 caagatgcga tctaatccat caatcaatgt cacttgtttt ccagattcga caaaagcttc
     5341 tactaattca ataccgatat atccaccacc aacaattact acacgttttg cttctttcgc
     5401 ttgtgcaata atttcatttg cttgattgta gtttttgcat aggagtacat ttttcgcatc
     5461 gattccacta atcggtggga taataggcca tgaaccagtt gtcatcacta atttatcata
     5521 agaaaccgtt tctgtttctc ctgttttcag atcttttgcc gttactgttt tattttctgt
     5581 atcgacgtct gttacatcgt gttccatttt aactgttgct cctaatgaag ataattcttc
     5641 aggatttgag tagaacaagc ctgctgggtc ctttactact ccgccgacat aaagtgcgat
     5701 accgcaagat aagaaagaaa tattgtcatt tctttcatat actgtcactt ctgcttctgg
     5761 atgatttttt aaaatacttt ttacagctgc agtacctgca tgagtacagc caattactac
     5821 tactttcatt tatggtccct ccgattaaca ttttgtcctt cgacaaaact actataacag
     5881 aaataaaacg gatacaacag tttaatgctt gtgaattcac aaaggtttgt ttgtagtttc
     5941 attccttttc aagcataaga acccaatatc tacaagattc ttattttaat aatattcact
     6001 tttatatcta agattgtgaa taaaagacaa aaaaataaaa aagctagcgt tttttttaca
     6061 cagctagctt tttttaggta taacacttgt agaaactgtt tttacatttg cgcctttttt
     6121 gctgactctt tacaatccgg acagagtcca tacaattcca accgatgttc attaatctca
     6181 aaatcagtca gtctgcttgc agccatttct atatcttcaa gccctgggta atgaaaatca
     6241 acaatcttac cgcagttttc acaaattaca tgataatgac gctttgaact gaaatcaaat
     6301 cggctagaag catcgccgta cttcatttct tgaacaaatc caatcgaagt aaataagcga
     6361 aggttattgt aaacagtcgc aacactcata tttggaaacc gatgttcaag tgctttataa
     6421 atctcatcag ccgttggatg ggaatgatgt tcaatcaaat attctaaaac cgcgtaccgt
     6481 tgaggtgtga ttcgaatgtt ctcttttttt aacttttcga taacctcttc gactaactta
     6541 ttttccatgt aaacacccca cgttgttatt ctcgtcttat catactattt ttacatttta
     6601 aaatccactt aacatgaaaa gaaaattcaa ttttattgta ttttaatgaa aaaagacgta
     6661 aaacagtcgc gttcactatt ctacgtctct attcaaataa tttttctcat cataaatttt
     6721 tgtgtgttct tttcatcttt aaaagttttt tacataaacc tatctggaga aaaaccaagt
     6781 gccttatatc tcttggtaaa gggctgtaga taaataacgt tcaccattgt cgggaaccac
     6841 agctaatacc ttcttgcctt ttcctaattc ttttgcgact tttagcgcgg cagcaattgc
     6901 agcgccagat gagatgccta ctaaaatccc ttcttttcgc ccaacttctc tagctgtttc
     6961 catcgcttcg tctccactaa tagaaaggac tttatcatac acagaagtat ccagtgtttt
     7021 aggaacaaaa cctgtaccga ttccttggat tttgtgaggt cccgcttctt tcccttctaa
     7081 aatagcagat tctgctggtt ctaccccgat taattcgatt ttcggataca cacgttttaa
     7141 ttctcggcca gcgccagtga tcgttcctcc tgtaccgata cctgcaacaa acgcgtccaa
     7201 gccatttact ccaaatgctt gatgtatctc aggaccagtc gtcttctcat gcacaagagg
     7261 atttgcttca ttttcaaatt gtaatggtaa aaagtagccg ttttcttttg ccaaacgttc
     7321 tgcttctctg attgatccag aaataccatc cgcaccagga gtcaaaatca actctgcgcc
     7381 gtaccctttc atcaataaac gtctttcgat actcatcgtc tcaggcatca cgatgattac
     7441 tttatatcct tttgcaactc ctaccatcga caatccgatt cctgtatttc cagaagtagg
     7501 ttcaatgata gtatcacctg gtttcagtag accatcgtgt tctgcttttt ctatcatact
     7561 taaagcaata cgatctttta cacttcctcc tggattaaaa aactcaagct ttacaaaaac
     7621 atctgctgaa tcttctggta cgattttatt taatttgacg attggcgttt tgccaatcaa
     7681 ttcggtgact gagttataga tagctgtcat cttcaattcc tccttgtctt tgctcttctt
     7741 acttatcata atacaatctg ttcatttatg gcgagtgatt cgtctttgac tagcaaaaaa
     7801 aagacaaaga tataccatat atggtaat
//
LOCUS       DARBDN010000108         7649 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000108 DARBDN010000000
VERSION     DARBDN010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.111"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(63..791)
                     /locus_tag="SCH06_002415"
     CDS             complement(63..791)
                     /locus_tag="SCH06_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1078948.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(804..2084)
                     /locus_tag="SCH06_002416"
     CDS             complement(804..2084)
                     /locus_tag="SCH06_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1078949.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIDDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2225..2827)
                     /locus_tag="SCH06_002417"
     CDS             complement(2225..2827)
                     /locus_tag="SCH06_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEG1078950.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3072..3278
                     /locus_tag="SCH06_002418"
     CDS             3072..3278
                     /locus_tag="SCH06_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078951.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3590..4309
                     /locus_tag="SCH06_002419"
     CDS             3590..4309
                     /locus_tag="SCH06_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEG1078952.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTNK"
     gene            complement(4390..5073)
                     /locus_tag="SCH06_002420"
     CDS             complement(4390..5073)
                     /locus_tag="SCH06_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEG1078953.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5291..7477
                     /locus_tag="SCH06_002421"
     CDS             5291..7477
                     /locus_tag="SCH06_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEG1078954.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2739 a         1291 c         1439 g         2180 t
ORIGIN      
        1 aaaaagaacc gaagggtttg gatcggctgg tcatttagtc ggtccaaact attcggttct
       61 ttttatgaaa tcaatttctt taatccacgg atagaggctg ggatggtctc gccgtttgcc
      121 aacgtgactt ctctggtttt tttattaatc gaccgcacat tttgtgtatt gataacatag
      181 gatttatgac aacggataaa attccgatgc attttctcga tttctttgat cttctcatag
      241 aattgtaatt gggcatgagt caaatggact tccagtttat gtggcgctcc tagcgaagta
      301 gaaaaatatt ggatgtcttt gatcggtaaa aatttgatct catcattaaa ctctattttg
      361 aagatatctt tttggatttg ggacatttga aaatcttcga aaattttgct caggatatgc
      421 tcgacatttt cttttaaatc ataaagatct tctttgacga tataatcagt cggttcgatg
      481 ttgcttttta agattttcat cgacatttcc gtatgggaag tcacatagat tatttttcct
      541 aaaggatcta attcacggat caatttaccg atcgctacac catccatttc actgtcttct
      601 agttcgatat ctaaaaagta aataccaaaa gaagaagttc tgatcttggc tgcattgaga
      661 agttcttccg gatcagaggt agaaatatgg acataactgt ctaagttttc aatcatgatt
      721 ctatttttga tcaccgttga taaaacttct aattgttttg gatcgtcttc acaaatataa
      781 atgggaatca tatcattact cctttatttt atttgtatat aaatcgtttg agaaaaacgc
      841 tggttttcaa ttgatgtttc aaggaaaaga taaggattgg tctttgtcaa ttcatccaag
      901 ataaacaagc caaggccttc gttttttgga tttgtttttg ttgagaaccc tttttgtttc
      961 aactggttta acggtaatgt atttgttgtt gtattgatca cacgaatcat cacggaatga
     1021 ttcttcttga gtatggtcaa ttcgattttt ttcttctttg cagcactagc tccttcaatc
     1081 gcattgtcca agataatacc aagcatacgt acaaggttta ccgtatgttt cgtatccagt
     1141 tcgattggct caggaaaatg aagctggacg atcaaccctt tttcctgtgc catcatgagt
     1201 tttaatgaca gtaaactacg gatctcagga actttcatat tatccaacat acttagattg
     1261 gccggaaaaa ggttcatcat ctggcgtgta ggtaatatcg tttgatcata ataagaccgt
     1321 aatccttcta agtcgccttc tgaaatatag ctgtgaagag aaaaaagcag attttggtaa
     1381 tcatgtttga attctctcaa gtcttgatag tttttttcta gatctttgat ataatcctgt
     1441 tgcatcctga cttgttgctc taataactga tcagctaatt tcttattaga gattttccaa
     1501 taataaacca agatgatcag gccaacacac agatatagaa tgaaaaaact cgtattcaaa
     1561 gctaagacat caggtgtttc accagaaaaa cgggtataaa aaataatgat atagtatgta
     1621 aataatatca atgtcccgat cgtaccgatc atacggcggt ccacagtgtg aaaccaagtc
     1681 tctaacgatt tttttaaaca aaaagctaat aaagcagata aaaaagcgga taagacaatg
     1741 tgaaaatact gcaatgaatc tcctggttca ataaccgaag atttcaaaac aaaaaaatcg
     1801 tcgatgcttg ttaagtgatc tcctaaaagc gacgtcaata acccaaaagg aagcgcgtaa
     1861 accaattgtt gacgcgaagt cgaaaagaag aaaaaagtaa gcatcagcat tcctatagca
     1921 attagagcag taaaaatccc taaaatcgaa tagacccatc caatcaaaat acaagaaatc
     1981 agaatgactc ccgcaaacag atatttgtat cggatgtgat ggtcaatcaa taagatacaa
     2041 attgtgtaaa tcaaatattg caacgctatg gaccataaaa acataaagta cagctcccat
     2101 tgatttttac caaattatag cacaattagc gtattatttt tttaattttt cagggatttt
     2161 gaattcagaa ctcataccaa agcagcagcc agatacaaaa aagtcagata agttagttaa
     2221 ttgtttaatg attgtttttt tcatgaaaga ttcctccaaa attcatcaag tagtttgtaa
     2281 taggaagcaa cgtagctatt tctaaaacaa tcccaagtag caaataggta gaaaagtaag
     2341 aagctgagaa aaataaagta atgagagaaa aaattagaaa catgctgatc gccttcttta
     2401 ataatggggg acgtttctcg ggttcaatgg gattgattgc tgtacctctt gatccatagc
     2461 gaagcagtaa caaaaagcag ctgattaaca aaaagaccat cattgggaag gagatagtca
     2521 attgcagatg tttcatcacc aagggaacgc cccataaata aagtagtgtc cacagcagac
     2581 aaacgaattc agagtcggaa tgcaatccat aagcatatct gcggatgcag atataagaaa
     2641 gaaaggtgat tcctgtttcc gcccatgagc ctgtcaccag agaaaagact agaacgaccg
     2701 ctagttttcc aagattattc aataaaactt ctaaggcaaa ttttacttgg acatacacca
     2761 tatcttcttc cgatttgtct ccgctgaata aggcttctaa taatttgttc acaactttat
     2821 ctttcatctc atacgtacct ccaccacaaa ttttatgcta aaaaaaataa aaaacgtctt
     2881 ttgtttcata aaaagtggtt ttgacatcaa aaccgtcatg atctcctaaa aaaatcttcg
     2941 ttttccaaga accttaccaa aaaaagtgac agttttgata cgaaaagtac tttttatgac
     3001 aagtttgtgc tttttcgagt gatttatgtt aaaaaattac tgaccttata aaaggtgatg
     3061 gagggattct tatggaaaat gaacaattgt ttgaagtcgg cgaaacatat gcatttaaat
     3121 ctgatttatt tgaatcacca ataaaaggaa aaatagaaaa aatctatgaa aatagtgtga
     3181 tgatacgtgt catgaaatgc gcagtagaag acaatgatac cgctcataat ctgcactggc
     3241 agttagttgt acgcaaatca agtacaatag aagaataaaa acagataaaa tgttgagagc
     3301 ataaagaggt tgtgagtctc ccgtttagct ctgagttaca aggaataatg ttaaaaaaca
     3361 gcttttcatg ttttatgaat attgccttgt gaccgaggtg ttggcaggag aatactgttt
     3421 atttgaaaaa agggctgcga caagactttt gtcacagcct ttattttcat gaataggagt
     3481 tacttttggc tacttttaga gaagtagctt ttaaggagca gataaagtca aggcttttat
     3541 ttctataaat gaagtagtaa aatgaagaac agattttatt acaggaagga tgccgataat
     3601 tgtgatcatt gttgcaggaa cgatcggtgc agggaaaagc acactaactg aaatgcttgc
     3661 ccaagattta gaaacaaaac ctttttatga gaacgtggaa gataatgaag tattgccgct
     3721 attttattct aatccagaaa agtatacttt tttattacag attttctttt tgaacaaacg
     3781 ctttttggca atcaaagatg ctttcagcca tgatgacaac gtactagacc gctccatcta
     3841 cgaagatagt atgctgtttc atttgaatgc agatttaggg cgtgtttctg aagtagaagt
     3901 aaagcagtat gaaggtcttt tagaaacgat gctgaaggag ttagaagaaa tttcgccaca
     3961 aaagaaacca gatctactgg tttatattcg tgtatccttt gaaactatgt tagcgagaat
     4021 caaaaaaaga ggccgggaat atgaacagct agaacaagat cctgaactct attcctacta
     4081 taaagaactc aatcgacgat acgaagagtg gtatgaacag tttgatatat gtcccaaaat
     4141 agtgatcgat ggggacaaat atgatttcgt agccgatccg gcatgtggag aacaaatcgt
     4201 acaagaaatc aagatgcggg caaagaaaat gacagaagag gcagatgccc agtcgatccg
     4261 ctacactaca aataacccga aagcaaaggg aatctttaca aataaataat ataaaaacta
     4321 agcaaattgc tcactcgcag atatttctct gtgagcagca tcttgcttag tttttttgat
     4381 tcattgagat caaatagtga accgattcgt atgataaaat tgccataaat gaaatgtctg
     4441 agtgagggcc atgatcaaaa ataaaatgga aacgatcaaa atcgaatggg cgccaaacag
     4501 atgatgacag aaaacaagga caatagctcc tgcgataaag gcaagaacga cacttagata
     4561 gtggaaaaat cgatcaaaat ctgctttttc tttagaaata caataatcat ataagttcgt
     4621 tgctacccct tttaaatttc cagttgtaaa taaattagtg taggcacgcc cgttgatttt
     4681 atcaaaagct acccactgga tcgatgcagt aaaagcaatc aaaatcgtta ctaatgcggg
     4741 atgctcatgg acgggtgtca aactaacaaa gaaaaaaatc actgcttcat aatatagaac
     4801 aaacaagcgc cagaaatgtt tttctttttt tctaaaataa tcaattagat actttgttag
     4861 aagaatccct aagaaaaaga aaagggtaga caatactttt ttaccaacac ttagccattc
     4921 tccgtcaaat gcttggatga tcgatagaat gatattgcca gtttgagcag aggcaaaagc
     4981 accatattgg atataagtat aactgtccat ggctcctccg ataaatgtca gcaaaagtcc
     5041 tattgtacgc ccctcgtgaa aggaagtctg catttttttc atcacctttt atgaatattt
     5101 ttgtcttcct tatcttagca taaacgattg aaaaaaagga aaaattttca gaaaactaaa
     5161 atcatatcgc ttcccatttt catttttaga aaggtctgtt agtataaaga aaaaatagac
     5221 aacgaaactt taaataacca acttgaaata aacaaattca aagaagaaag atgggaagga
     5281 aatcaatcag ttgaatgaaa aagaaattct ccgattacaa aaagaattga aacgctggga
     5341 gaacaagtat aaaaagcttc aacaagtctt tcggctacaa gaagaaatca ttgctaccta
     5401 tgaagcggct tatggcgaag cacccggact tattgaggaa gaagtacaag taaaagaaag
     5461 tgaaggaaac agctctttct ttaaaatgat ggagaaacgt tcctataatc gcttcaatca
     5521 agaacaaaaa gcagctatca catatgatat gaagaaacat cttcgaatca tagcaggagc
     5581 tgggagcggc aaaacgcaaa caatctgtgc aaaagctgtt tatctgatga cgcaaaaaca
     5641 agtagacgaa gaacgcatac taatgatcac ttttacaagg aacgctgcaa atgaactaaa
     5701 aaaacgagta gataatttca gccagagaaa aaccgctgtc catatcggaa cattccatag
     5761 tatctttttt aggatataca atgaaatttg tcgaaaattt cctgaagtag caatgcaagg
     5821 aatacaagga gacttttcaa aggatactgc acaaaaagtg aatgctgttt tgcaacagct
     5881 gatacgtaaa tataatcttt atatatttga tcaatatgga gaaaaaacga ttgcttctcg
     5941 gttagactat tggcagaata tgaacctttc agtagaagaa atggttcagt tagttaaaga
     6001 aaaatatgat tccattgata agaatgcacg acagccgata tcagaacgac tgtatggatt
     6061 gctcacggaa ctccaagaac aaaaaagaag ccagcaattg ctagagttca atgatgtact
     6121 ccaaaatctg aaaagcgctt tggagaatga ggagatccag cattatatcg gccaaaaata
     6181 tgattatcta ttcattgatg aatttcaaga tactaatcca cttcaatggg aaatcgtgaa
     6241 acggatgaca aaggaaaaca ggatcaagtt gattgttgtt ggagatgatg atcagagtat
     6301 ctatggattc agaggatcag agccagcata catcaagaac tttgaaaaag aatatcctac
     6361 caaaactctt ttcttattga ctaattatcg ttctcgggca gctattgtcc aaggagcaaa
     6421 tagattgatc agctataata aaaatgatcg gataccaaag gcgatgattc cagcacaaaa
     6481 agaagcaggt gttatggaag cctatttgtt ttctgatact aaagcagaaa gtcagtggct
     6541 aatcaaacaa attcagacat ttattcaaaa aaatgggaaa tataaggaat caatcatatt
     6601 ataccgatca gcttcacaaa cgcagcagct tgtccaatct ctgctgaaaa cgaatattcc
     6661 ttttgtactg gaagcagata gtccatatga aggtatcttt ggtatcaagt ctttccaaca
     6721 tttctatcaa aaaattgttc attggcaaac agcactgaat ctgcaaaaga aaaatcaggc
     6781 ctaccagcaa ttgctccggc agctgatggc agactgctac ctgaaaaaaa gtgaatgcga
     6841 tcaatacttt tctcctaaat atcaaaatat agccgttgca gattatattt tgtcgataag
     6901 ccccaattta aaatcgaaat ctgcagaaat ccgagagttt gaggaagcgt tgcgtaaaac
     6961 agaccagcat caagaaatct attcgcttgt tcaaagctat cttcatctgc cacgtatagc
     7021 taaggaaatc gaccagagtg atcaagaatg gatacgagaa gaagtaaagc agcatgctac
     7081 tttcagaaga ctccaagcct tatcgcaaga aacccaagcg acagctaaag aattaaaaac
     7141 ccgcttgatt gcttacagac aaggaaaact tgatgcacta tgtatccaga gcattcacaa
     7201 aagtaaaggt cttagttacc gaaatgtctt tttgattggt tgtaacgaag gaagtttgcc
     7261 ttataacgga gcgacagaaa agaaagtaat cgactttaat gaaataaaag cagaaccagt
     7321 gacgacgata gaagaagaac gaagactatt ttatgttgcg atgactagag caagaaatcg
     7381 tctgtatcta tgtgtacctc aaatgaaaaa ttcaagaaaa ttgaaagtat cgagatttat
     7441 caaagaaacc gggagtcgtg tgaaaaaagg aaagtgatag aagagagggt gtgacagaag
     7501 tggtcagttt caagaaagaa gaaggaatgt acgaaaattg cttctcaaat ttttgtgaaa
     7561 tttcagctta ttttcgaaga agctatttct ggaacacagt ttattcggaa aagggaggtg
     7621 tgacaagaat tttgtcacac ctcccttat
//
LOCUS       DARBDN010000109         7641 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000109 DARBDN010000000
VERSION     DARBDN010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.112"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..179)
                     /locus_tag="SCH06_002422"
     CDS             complement(<1..179)
                     /locus_tag="SCH06_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEG1078955.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAIN"
     gene            complement(192..1295)
                     /locus_tag="SCH06_002423"
     CDS             complement(192..1295)
                     /locus_tag="SCH06_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEG1078956.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(1385..2341)
                     /locus_tag="SCH06_002424"
     CDS             complement(1385..2341)
                     /locus_tag="SCH06_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HEG1078957.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            2622..4556
                     /locus_tag="SCH06_002425"
     CDS             2622..4556
                     /locus_tag="SCH06_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEG1078958.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5013..5429
                     /locus_tag="SCH06_002426"
     CDS             5013..5429
                     /locus_tag="SCH06_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEG1078959.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            5443..6009
                     /locus_tag="SCH06_002427"
     CDS             5443..6009
                     /locus_tag="SCH06_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HEG1078960.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6032..7018
                     /locus_tag="SCH06_002428"
     CDS             6032..7018
                     /locus_tag="SCH06_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEG1078961.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(7173..>7641)
                     /gene="scm"
                     /locus_tag="SCH06_002429"
     CDS             complement(7173..>7641)
                     /gene="scm"
                     /locus_tag="SCH06_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEG1078962.1"
                     /translation="TSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTS
                     DSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNF
                     NLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2192 a         1463 c         1576 g         2410 t
ORIGIN      
        1 ttattgatag cggtagtcgc taaatcaaaa actagcattc caataaaaaa taaaaaagtg
       61 tttagccaat gtatctcatg aaaaaaagcg atagagaata atacccctac cgcaaaagga
      121 aatacactag ccacctttgt tcgtatttca actacttcta aaaagatttt tagtgtcatg
      181 gttcgtactc cttattttag ttcagaacgg tcacccatcg tgtaatggga gtcctccgat
      241 aatttgaagg tgtctttgat tggatcggtc acatatactt tatcgtcttt tgtcacgaag
      301 atcgcttccg tcccgttatt caattcgctt tcgacgtatt ccagtccttt tttcacaccc
      361 attgaaaaga ctgctgtaga caacccgtca ccatcaattg atttatctgt tatgatcgtg
      421 acacttgcga tatcattgtc gaacggataa cccgtttttg gatcaaacaa atgatggtat
      481 tttttgccat ctacttctaa ataacgctcg taaattccag aggtaactaa tgttttgttc
      541 cgttctttaa tagaacctaa aacagatccg cgagccatgt tcggatcttg gatgccgact
      601 gtccagtctt ggttttcgcc tcttgggctg tggcctaaga catagacatt accgcccaag
      661 tcaacgatgg cagtggtcac tccttgtttt ttcaagactt tcactacttc gtccgtaatg
      721 taacctttgg cgattgcacc taaatcgatg atcattcctt tttcttttag ataaacagtt
      781 ttttctttgt catttagttc gatcttatga taatccacta atttcaatgc ctgatcgatt
      841 tcttcttggg aaggttttct ggcgtcatca aaaccgattc gccataattg tgtgattgca
      901 ccaatcgcca tatcgaatcc gccttgagaa tcttggctat attcgtaggc ccgcttgact
      961 aacgtgtaga cgtcatcaga aacttttact ggtttgatcc cagcttgctc attcacttca
     1021 tcgatctcag aacctttttg attgatcgtg attttatcac caagttcttt tactcgatcg
     1081 aaggcaggtt tcaatgctga ttctttgcct tcatcataca cacggatacg aacgtaagtc
     1141 cctaacaaga actgttcatc agaatatgga tctttcaata tcttggtagc tgctgaactt
     1201 tcagtggttg ttttatttgc tgagttgctg cagccagtta gcaccataaa agagatgccc
     1261 agtgtgatta aggaaaatag tagttttttc cgcatctttt tcctctcttc attttgaaag
     1321 gtgagacgac tgcctaatct ggctatcgtc ccaccctcca acttttatta gtatgattat
     1381 gtgattattt ttctgttacg atattatcta cttcgattgt ttgagtgtcg cctttttcag
     1441 ctgcattcac taattgttgt gcgtacatga tgaatgaatg tgagctgtgt gtagcacctg
     1501 taacaacttc tacattagca ggtgagccat cttcttcgcc cattgctttg acgaattcgt
     1561 cgttcagagt agggatgtaa gtttttggtt ctgtaccgct ttttgctttc atattttcat
     1621 tatattctgt atcatcttgt tttgatttac cgtctttgtc gatataatca aagtttgatt
     1681 cagttacttt gccgccagca actgtcattt cgaattgcac acggtagccg ttagagtagt
     1741 tcttttcttc aagcttgtaa gtgccgtctt tcaaatcagc accattgtcg atttcgattg
     1801 tatctgtgtt accagcttga gcagcttgga tcaattgttg tgcgtagttt tggaagcttt
     1861 cagatgagtg agtagctcca gttacgactt ccacaccgct tgcgctttgt gcttttaaga
     1921 attggtcatt caactcagga atgtattttt ctgggtttgt gccagatttt gcttccatgt
     1981 ttttgttgta ttctgcatct tttgtttttg attcgccgtt ttcattgacg ttatcatatt
     2041 ttgattcagt gattttgccg tcttttacaa ccatttcaaa gactgcacgg taaccatttg
     2101 aataattttt ttcttctaat ttatatgtgc cgtcttgcaa atctccgcca gctacaactt
     2161 ttgcagatga ttctgttgtg ctttttgcag tcgaagattg tgctgtagat gattcagaag
     2221 aagagtttga gcttccgttg tcatctgcgc cgcaagcgcc taacactaga gctgaaaatg
     2281 ctaatacggc aaatccagtt acaaaacgtt ttttcttcat tttaataccc caccattcca
     2341 tttctagtcc acaatttttc tttgtgattc attatacatt ctaatctttt tagcctataa
     2401 gtcaactatt tttgataaat aacccatgta atatttcaaa cgttttcttt cagcaaattt
     2461 cgtgaaaaaa cgctttattt taaaatttga aaaaaatcca aaaggagtta gacaaaagaa
     2521 cagaacatct atataatata tggagattgt gtaataagta tcaaactaaa agaattatca
     2581 tatattcatt atatagatag tctataagga gcggatgatc aatggcaaag caaaatattg
     2641 tcgttgtagg agcaggatat gccggtgttt cagctacaaa atacttggca aagaaactga
     2701 aaaaagaaga tgtagcaatt actctgatcg atcgtcattc gtaccatact atgatgaccg
     2761 agttgcatga agtagctggc ggacgtgtag aaccagaagc aatccaatac gatctgcagc
     2821 atttgtttgc tcgtcaaaag aatgtacaac ttgtcacaga cactgtaatc ggtatcgata
     2881 aagaacgaaa aatcgtcaag accaaattag gttcctatcc ttttgatcag ctgatccttg
     2941 gaatgggcgg agagccgaat gactttggta cacctggtgt caaagcacac ggattcaccc
     3001 tttggtcatt tgaagattct gtaaggattc gggaacatat tgagaagaca gtagcaaaag
     3061 ctgcattgga accagatgat gaactgcgta aagccatgct gactttcgtt gtctgtggtt
     3121 ctggatttac cggtattgaa atgattgggg aactgatcga ctggaaaaat cgcctagcca
     3181 aagattataa attagatcca aacgaaatca cactgatggt cgtagaggca atgccgacga
     3241 tcttgaatat gttggatcga aatgatgctg caaaagctga acgctatttg cgtaagcaca
     3301 acgtggaatt attattgaat gcaccaatcg tagaagtggc tgctgatcat atcaaattga
     3361 aagacggacg caacattccg actcacacac tgatttggac agctggtgtc aaaggaactt
     3421 ctgacgctgc tgactttgga ttagaatcag cacgcggaca gcggttgatc gccaatgaat
     3481 atatgcaggc aaaaggctac gaagataaaa acatctatat cattggtgat ttagtctttt
     3541 atgaagaatt cccaggaaca ccgacaccgc agatcgttca agctgctgaa caaacaggac
     3601 acacagccgc agcgaatatc gtggcttcga tcaaaggcgg agaaaagcat aaatttaaag
     3661 gaaactatca aggatttatg gtttctattg gtgccaaatg gggggtagct aacctatttg
     3721 ataagatcca tttaagcgga tttttagcta tcgtaatgaa acatatcgtg aatttgaaat
     3781 acttctttga tattcgttct ggttattata tgttccaata tttaatgcat gagtttttcc
     3841 atatcaaaga tgatcgcaac gtgactcgag gacattcttc tcgttacggc aatgtcttat
     3901 ggagtgtgcc acttcgtatt ttctatggtt tagtttggtt cgttgaagct tccaaaaaaa
     3961 tcattgggaa tggtgaagtg ttcaaaccaa gtacttggtt tggtgaagga tcatggttca
     4021 ctggaaacag tgtgttccct tggacatggg aatacaatgt aacagatgtt gccagtggtg
     4081 cttctgctgc tggtgatgca accacagctg ccagcggagc aggggcaagt gccggagaag
     4141 cagcgactca agctgcacat tttggtttga gttatgcata cggtgaagaa ccaatggctg
     4201 tgattgagaa gtcaccagac tggttcacaa agatcatgca agtgatcatg ccaaacaatg
     4261 atgtagcaat gttcttccaa aaattcatgg tattctttga aattgccttg gcattagcat
     4321 tgattgctgg attattcaca tggctatgca gtgcgacaac gattgtattg gtgatcacgt
     4381 tctgcttatc aggcatgttt tactgggtaa acatttggtt catttttgtt gctttcgcat
     4441 tgatgaacgg ttccggacgt gcgattgggt tggatcgctg ggtaattcca tggctacaac
     4501 gtacactagg taattggtgg tacggtagac caagttccca gtacggcaag aaataaatag
     4561 ataaagaacg ttatttgaat gcaagatttc aatagaaagg ggctgagaca aaccgtcaca
     4621 gcctcctttt tatgtaaaat taaaggaata agatgcccga gataagcctc catgagcaag
     4681 acacaggtgt cacaacctct gttacaacct cttgttataa acggtgttcc agaagtagct
     4741 tcttcgaaaa ataagccgaa atttcacaaa aacttgaaaa gtaattttcg taaattcctt
     4801 cttatttctt gaagttgccc acttctgtca caacctcttg ttataaacgg tgttccacct
     4861 gctgcttctc ggtaataagc ccaaagaatt agaaaacatg gaaagctgtt ttctattctt
     4921 cgttcttatt actcaaagca agacacaggt gtcacaacct cttgttttta tgctaaaatt
     4981 gggtgagtta atctggaaaa aggagaacaa aaatgagcct taaagaattt gctgaaaaaa
     5041 gtctgctcaa accttgggat gtttttatta ttttgctttt gactgttctt tcttttttac
     5101 cagtcatgat ttttggtctt cagcaaaaca ccgcaacagc agaaaaagaa gcggtactgc
     5161 gtgtggatgg cacagaaatc aaaacattcc ctttgatggc tggagaagag agcaacacat
     5221 atacttacaa agatgaacac ggagattata acttgatcga gatagatggc gatcgagtac
     5281 ggataaaaga agcagattgc gatgaccaga tctgcgtacg tcgaggctgg gcaacgaaaa
     5341 atggcgaaac catcgtctgt ttgccacata aattagtgat cgaagtccgt tcaacagatg
     5401 gaggtgacga agacagtctg atttattaga ccttcacaca ccatgagtaa attacaaaaa
     5461 atgatttata tttcgctact tgttgcacaa ggagtgatca ttggtttatt ggaaaatatg
     5521 atcccttatc ctttttcttt tgcgcctggt gcaaaactag gcttagccaa tctaatcacg
     5581 atcgttgcca tttttaccat gaaaaaacaa gacagcttct tactactttg gctacgacta
     5641 ttcctgacta ctttgctagg cggaacgatt tccacattcc tttatagtat gagtggtgct
     5701 ttgcttagtt attttggaat gttattggtc aagcaattag gaccaaaacg tgtcagtatc
     5761 atcggaatta gtgcggccgg cggtttcatg cataatgtcg gacagctttt gatggcttct
     5821 ttcattgcac aatcatggac agtcatgttg tacttgccag tcctttcagt tttagggatt
     5881 ttatcaggga ttgcaatcgg gatcgcagcg aattatcttt tacgacatgt gcagacactt
     5941 caacgattcc aaaaagatta tgagcaggga accaaacaaa aatggagccc aatgtttacc
     6001 aaaaaataat cgtcacacaa ggagtttttt tatgaagcta catccaatgt gggaaaacta
     6061 tcctgcttta agtaaagaat tgacagaaac actaaaacgg atggaagaaa ctgtccgcct
     6121 gaaaaacaaa cctgtcgaac aagccatcaa agaaacgatc catgccggcg gaaagctgtt
     6181 gcgtcctgcc tatcagctat tgttctcaca atttggacca gagcaagatc gagacaaagc
     6241 catcgctttg gcagcttcta tcgaaatgct ccatacggcc acactgatcc atgatgatat
     6301 cgttgatgaa gcggatctgc gacgtggtca gcctaatatc cgtagtcagt ttggtaatgt
     6361 cgtttctgtc tatgcaggag actatttatt tgtctgctgt tttaaactat tgtctgatta
     6421 ctccacttcc ttgaaaagtc tccaattgaa ttctcgcagt atggaaaaag tattgaatgg
     6481 cgaattaggg cagatggatg atcgctataa ttatgaactt tctgtaaaag aatatttgga
     6541 aaatatttca ggtaagacag ctgaactgtt ccaattaagt tgttctgttg gcgcttttga
     6601 aagtggaaca agcgagcgct tcgcaaaaaa agcaggagat atcggacttt ctatcgggat
     6661 ggcctttcag attatcgatg atattttaga ttatacaaaa gagagccagg aaatcggcaa
     6721 acctgtacta gaagacatgc gtcaaggggt ctattcttta ccgttgatct actctttgca
     6781 aaaaaacaaa ccaaagctac taccttattt agagaagaaa gcggcaatga cagaagaaga
     6841 tgtcgacgcc gtacgcaaaa tcgttgaaca tacaggaggc gtggaagaag ctaggaagtt
     6901 agcggcctct tacacagaaa aggctttgaa ggaaataaag aaattacctg ccacctctct
     6961 tcgaacaaaa gagaatctct tttcccttac ccaactgatt ttggatcgca aagactgaat
     7021 agggaaaggt tcgatacgta aataaatttc tcagaaggaa atctacgtgt tttttgacaa
     7081 attgaattgt agttcttgta tttatgataa aaagcaaaaa taaagagcaa cgtccgttag
     7141 cgacgttgct cttttttatc ttgaatattt ttttaccttt tcgatttctt ataactcata
     7201 aaagtgattc ttaaaccgat tacaagtaat ataacgcctg cgagtgttat ccaattattc
     7261 gattgacttc cagttttagg aagtgctctt tttgatttgt ttccattgtc attgcttgtt
     7321 ttattagtta agttaaagtt cgtcctgtta tccgaacttg tttttgagaa ggagacactt
     7381 gcatgacgtg tatcgcttgt ggtagacgac gtgtctgtac tatcgcttga agttgatgaa
     7441 tctgagctat cacttgtggt agaggatgta tctgtactgt cacttgaagc tgacgtgtcc
     7501 gtgctatcac ttgtagtggt agatgaatct gagctatcac ttgtggtaga ggtagtatct
     7561 gtactgtcac ttgaagctga cgtgtccgtg ctatcacttg ttgtggtaga tgtatccgta
     7621 ctgtcgcttg aagctgacgt g
//
LOCUS       DARBDN010000110         7615 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000110 DARBDN010000000
VERSION     DARBDN010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.113"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(94..1242)
                     /gene="nagA"
                     /locus_tag="SCH06_002430"
     CDS             complement(94..1242)
                     /gene="nagA"
                     /locus_tag="SCH06_002430"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEG1078963.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1318..2154)
                     /locus_tag="SCH06_002431"
     CDS             complement(1318..2154)
                     /locus_tag="SCH06_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1078964.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2338..3555)
                     /locus_tag="SCH06_002432"
     CDS             complement(2338..3555)
                     /locus_tag="SCH06_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEG1078965.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3704..3883)
                     /locus_tag="SCH06_002433"
     CDS             complement(3704..3883)
                     /locus_tag="SCH06_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078966.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3938..4021
                     /locus_tag="SCH06_002434"
     tRNA            3938..4021
                     /locus_tag="SCH06_002434"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3972..3974,aa:Leu,seq:gag)
     gene            complement(4261..5631)
                     /locus_tag="SCH06_002435"
     CDS             complement(4261..5631)
                     /locus_tag="SCH06_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078967.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYVF
                     EKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEI
                     NRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELI
                     FSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLI
                     FLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLF
                     TELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLI
                     MGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFI
                     ITVINR"
     gene            complement(6345..6635)
                     /locus_tag="SCH06_002436"
     CDS             complement(6345..6635)
                     /locus_tag="SCH06_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078968.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(6843..7535)
                     /locus_tag="SCH06_002437"
     CDS             complement(6843..7535)
                     /locus_tag="SCH06_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEG1078969.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQALTDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         2312 a         1516 c         1177 g         2610 t
ORIGIN      
        1 tttgaaactt atgtaaagtg atttttacta gaacacaaaa aaaccttaaa accaaactta
       61 agaagtttag ttttaaggtt aacttaaatt atattatgcg tggaaacgtt ccacgccatc
      121 tagataagtt gcttccaatg tcatatcagg gttcaatacg ataaagtctg catcgcgtcc
      181 ttgagcgatt tttccacatg tatcatcgat tttacagctg attgctggaa tcagactagc
      241 catcatgact gcttgttctg gtgttgctaa tccccagtct acaacatttt taattgcttc
      301 tttcaatttc aatatacttc cagctaagtt gccagattct agacgtgctg ttccttcttt
      361 tactactact ggaaattcgc ctaaattgta atttccatca ggcatcccac cggccatcat
      421 acagtctgta attaatgcga catgatcatg tcctgctttt tccattagga ttcccgcagc
      481 atttggatgt acatgatggc catcacaaat caattcagaa aagacatgtt ctaaagataa
      541 taacgcaccc accatacctg gttcgcgatg attcaatcca cgcataccat tgaaagcatg
      601 gacaaataca cttgcgcctg cttcaacagc tttttgcgct tcttctagtg tagcattact
      661 gtgtcctaga gaaacaacta ctccttcttc agtcacttgt ttgacaaact cttctacacc
      721 ttgacgttcc ggtgctaaag caattttttt gattaaacca cctgaagctt cttgccattc
      781 atggaaagta tccaaatcag gatccccgaa ataacttggg ttttgtgccc ctttgtgttc
      841 ttctgtgaag aaaggacctt caaaatagat tcctttgatt ttagctcctg gtgcttcctg
      901 atacattttg ccgattgtct cagctacatc ttttaaacgt tctttgcttg acgtcaatgt
      961 tgttggtaaa aatgaagtca ctccacaaga taacagacct tcagacatca ctttgatgcc
     1021 ttctgcatca ttatccatta catcatgatt catatagccg tgaatatgtg tatctaccaa
     1081 accaggagca atccatttgc cgctttggtc aatgatgttg acttctccct caggtagttc
     1141 tttggtgtat tcaccaaaaa gtccatcggt aatttcaaga tagcctgcat gtttgacacc
     1201 tgacgctaaa aagaatttgt cagcatagat aaaagttctc attctattct ctccctttgt
     1261 ttttctacct ctaaagtact cttatttaga gaagaagtca agaatggtct acaccattta
     1321 caaatttttt gaaatttgtt tcacagcttg tgctaagcct tcatagaatg ctgctctttc
     1381 tggttcttct ttacgcttgt atattaagct tttaagcaca aataaatcat tgaggtaata
     1441 gtagctattc ttctcttgag cccaatagat tccttgattc acctgttcta acgcttcgtc
     1501 gatttcattt tgatggaata agaaatttcc ataattataa aaaatttgcg aaaattcact
     1561 ttttgatcgt tcatcagctg attgatgcag cagttggatg cttcgactca aatagtagcg
     1621 tgcttcagcc gtttttcctg ccacaccata tatttttccg atacaactaa tcagttgtat
     1681 ttctgtgtca gaaacatgga ttctttcttt ttggctagag tagcttaatg cttctttcaa
     1741 ataataaagg gactgagaga tattttgacg caacgtgaat tcgcaaacac cgagataata
     1801 ataatagcgt tgaaagtcag ttgcttgata cagattttca gaaatatcag aagattttag
     1861 tacttgttct aacttccgat aatcacgttt ttggaaacaa ctatccaaca gttcaaataa
     1921 tttatcgttt gtccgagtag tttttcgaga gagattcatc acatgatcaa tcgttacccc
     1981 tagccgttga caaatctgca tcatcaccaa tacattcggc agttcctcat tattttcgat
     2041 ccgacttaat acactttgtg aacaaatatc atgcgaaagc attttttgcg tcattttttg
     2101 ttcttttcga atctctttaa tgatcgttcc aaaggactcg attaacgttt ccataagtat
     2161 cctccccaaa atatgcgtat tcgcattcta ttcgtatttt actttaggaa gtcgcaaact
     2221 tcaagaaaag acttgcaact aaataatata ctttagttat ttaagaaaac tccactagaa
     2281 agagagcctc agtgtgtttg tctgtggccc tcctactgaa aaatttggtt tttaaaatca
     2341 tttttggcga taggttgcta ggaattctct cattttctta gctgtttgtt tcaaatcatc
     2401 cattttagga agataaacga ttcgaaaatg atctggctgg ttccaattaa atccaccacc
     2461 atgtacaagt agaatatgat gttcatgtaa aaagtccaaa acgaattttt catcatccaa
     2521 aatattgaat cgctttgtat caatttttgg gaatatataa aaagcagctt ttggttttac
     2581 ggctgaaaga ccaggaatat cattgattgc attatagata tattctcttt gttcatagat
     2641 ccttccgcct ggcaggagca gctcatcgac actttgataa ccgcctagcg cggtttggat
     2701 aatttgctga gacaatacat tggaacacaa acgcatggag gacaacatat tcagcccttc
     2761 tatatagcct ttgacgtgtg acttatctcc acttaggacc atccagccta ctcgaaatcc
     2821 tgctacacga tgagatttgg atagaccgtt cagcgtaaca acgaacaaat caggcgctaa
     2881 tgtagcaatc ggaatatgtt ctagaccatc catcactaag cgatcataga tttcgtcgga
     2941 ataaataatc aggttatttt gtcgagctac ttcaacgatt tcttctaata attcttttgg
     3001 ataaagtgcc ccagtaggat tattaggatt aatgataaca atagcttttg tccgactcgt
     3061 tatttttgat ttgatatcat caatatcagg ataccattct gcctcttcat cgcaaatata
     3121 atgaacaggt gtgcctccag ctaatgcaat agaagccgtc cacaacggat agtccggcat
     3181 tggaaccagt acttcatctc cattgtccag caacccctgc atacacatcg tgatcaattc
     3241 gctcactccg ttgccggtgt agatatcatt gatcgtcaca ttcggaaaat gtttcagttg
     3301 gcaatattgc tcaattgctt ttctagcaga aaagatcccc ttggaatctg agtagccttc
     3361 tgagtcacgg gcattcatga tcaaatcacg aatgacttcg tttggtgctt caaatccaaa
     3421 aggtgcggga tttcccgtgt tcaattttaa aatactaatg ccctcttctt gcatccgctc
     3481 cgcttcttct agaacgggac cgcgaacatc gtaactgaca ccttctaatt tgttggattt
     3541 ttcaaattct ctcatcactt agccaatccc tcatttcaaa aagttagaac tttccaaatt
     3601 ttttgttatt tactatttca atatcatact ccatcctaga aaattttgcc acttatttag
     3661 gaaaaacgta agtattaaaa aaacacaaac aagcgttgag aacttaattg tcatgatagt
     3721 cattccatag attcgctgcc caatccattg caattccaca aatgattcct agcataaaac
     3781 caagcaaaaa acgtccgaat gcaagtccaa tcaatacacc taagatcatt cccagtcctg
     3841 aaaattctcc gtcatatttc tccatcttaa taagtcctcc catttttgag cttgacaact
     3901 atgtaaaacc tcgctatcat tagtgtgtta ttattacgca gatgtgttgg aattggcaga
     3961 caagcatgat tgagggtcat gtgagcgtta gctcgtgtgg gttcgagtcc catcatctgc
     4021 actacaactc gtgaagttaa ttttgcttca cgagtttttt tgtttgaacg tttctttatg
     4081 ccattatata catatcactg tatcctttac aaaaagaacg tacaatcatg taaacagcct
     4141 gaggtgagta tatgaaggtc ggaaacaagc tactcgtaga aacttgcaag tgttaaaaca
     4201 attaatcgaa aaacgagtaa aatccctcac ctaatactaa agcgagggat tttttgtata
     4261 ttatctgttt atcaccgtta ttataaaggt acaaatacca agcacggtta atccaaattg
     4321 cataaattca tttttttgta cactcatgct tttcattagc tctttaactg ccattagtac
     4381 taagatggcg ataacaacat aaagtatata gtacgtccgc attccggaag cccatactgt
     4441 gggagaaaat cccataatta accttgaaca aaatcccatt atcatcaaaa taactaaaaa
     4501 aatagaagtt ttcttattgt caaaacttaa ataaattcca acaattaaac atagtaataa
     4561 tgccaagact actaaagtag ctatccaagt acctggataa aaaagtgaca gtttcgttcc
     4621 taactctgta aagagattat tcaggttact actactccaa atcattgccc ttttatttcc
     4681 attgacgtaa gtaaagcttt gacccattgt attaccaaaa taaataatca ggtttaagaa
     4741 aaacggtaat gcagtcaata tacgcacata atagttttga catttcctat atgttagaag
     4801 gaaaattaag aaaaatagca ataaaaataa gatattcatg tctaaaaaaa acggctttcc
     4861 aaatgatgaa atacctaaat ctaacttatt aagaaagttg aaatttttat attcaggaaa
     4921 ccatttatta atttcatgtg cagcacgtaa tgcattccct ggagttgtca aagagaaaat
     4981 taattctgct aagcttatta ttgaaaatac tgataactta taattatatc gtccattgac
     5041 aatcaaatat aaactaacta tacttgttag aacaaaaaaa caggcgttga cttgttcttg
     5101 attagttaaa aatatcaata aaggaatact tacccaatat atttttctat ttatttcttc
     5161 tcctcttaag agttgaaaaa acggataaaa agttagtaaa ctaaatgcta ctggccactg
     5221 atagttcaag gtggttgctc tccaaccggt ttcccccatt actgtcaatg gtattaaaca
     5281 gtatatagag caaaccaata ataaattttt aacatttatt ttctcaaaaa catacttgca
     5341 aagtaatact acaattccta acataatcgt agaatttaat aatttccata gcataaagtg
     5401 tttagaaaag aacattaaga atagttctat aataattctt gaactccatg tcttataatg
     5461 ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc
     5521 cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag
     5581 taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact
     5641 ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa agataactta
     5701 aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg
     5761 atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg
     5821 gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt
     5881 taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac
     5941 tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta
     6001 tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa
     6061 ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg
     6121 agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat
     6181 gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat
     6241 tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt
     6301 ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca
     6361 tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac aattttgggt
     6421 ttccctaaca catgatagga tctcacaaca aattgctttc tattattata ataacctgta
     6481 acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc
     6541 aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta
     6601 cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat accattatac
     6661 gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat
     6721 tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa
     6781 agaggcagca gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa
     6841 gattatttac gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact
     6901 tcatcttttg ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt
     6961 gcttcgtcta atttcttttg tgtatctgtt aactgagttt ctacatttgt tttttcttgt
     7021 gtcagtgttg cgatttgttg attcaaacca tttacagtat tttgtaattc tgaaagtttt
     7081 gcttgtgctt cttgtagtct tgctgtccaa tctgcattca gatgattgat ttcatcattt
     7141 ttttggttga tctcatctag tttgacattg atttcatttt gtttgctttg tagttgtgca
     7201 tccttgctga ctaattgact ttctaagttt tgtttttctg ctgccgattg atttttttgg
     7261 ttttctaatt catttacttt tgtttggtat tcttggacat ctgcctttga atcttgcaat
     7321 gtctgttctt tttgtgctag tcgagcggta agatctgtaa gcgcttgctc tttatctgtc
     7381 aatgtatgat caagctgtgt cagattctca ttgattgtat caatatctgt ctctccaccc
     7441 cacaaaataa tttcatttgc gtaccgcgtg cctgtgtagc caattagaca tagaaatgca
     7501 acgacaatcc caccagtaat aaatttcttt ttcatttgca tagctcctta atccaatact
     7561 tttacatgct aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa attac
//
LOCUS       DARBDN010000111         7601 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000111 DARBDN010000000
VERSION     DARBDN010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.114"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(943..1356)
                     /locus_tag="SCH06_002438"
     CDS             complement(943..1356)
                     /locus_tag="SCH06_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HEG1078970.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="SCH06_002439"
     CDS             complement(1812..2297)
                     /locus_tag="SCH06_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078971.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="SCH06_002440"
     CDS             complement(2436..2651)
                     /locus_tag="SCH06_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HEG1078972.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="SCH06_002441"
     CDS             2875..3675
                     /locus_tag="SCH06_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEG1078973.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIKEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="SCH06_002442"
     CDS             3694..5562
                     /locus_tag="SCH06_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEG1078974.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="SCH06_002443"
     CDS             5555..6046
                     /locus_tag="SCH06_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEG1078975.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="SCH06_002444"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="SCH06_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEG1078976.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="SCH06_002445"
     CDS             6606..7601
                     /locus_tag="SCH06_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEG1078977.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2709 a         1213 c         1442 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacataaaag aagggatata taaagtaatg aaacatttta agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgttcccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg a
//
LOCUS       DARBDN010000112         7259 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000112 DARBDN010000000
VERSION     DARBDN010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.115"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..515)
                     /locus_tag="SCH06_002446"
     CDS             complement(<1..515)
                     /locus_tag="SCH06_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEG1078978.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKK"
     gene            complement(515..1651)
                     /locus_tag="SCH06_002447"
     CDS             complement(515..1651)
                     /locus_tag="SCH06_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEG1078979.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDVVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            complement(1683..3134)
                     /locus_tag="SCH06_002448"
     CDS             complement(1683..3134)
                     /locus_tag="SCH06_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEG1078980.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            complement(3178..3942)
                     /locus_tag="SCH06_002449"
     CDS             complement(3178..3942)
                     /locus_tag="SCH06_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEG1078981.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            complement(3970..4668)
                     /locus_tag="SCH06_002450"
     CDS             complement(3970..4668)
                     /locus_tag="SCH06_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HEG1078982.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(4680..5459)
                     /locus_tag="SCH06_002451"
     CDS             complement(4680..5459)
                     /locus_tag="SCH06_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HEG1078983.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            complement(5475..6419)
                     /locus_tag="SCH06_002452"
     CDS             complement(5475..6419)
                     /locus_tag="SCH06_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEG1078984.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(6465..7244)
                     /locus_tag="SCH06_002453"
     CDS             complement(6465..7244)
                     /locus_tag="SCH06_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078985.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
BASE COUNT         1990 a         1563 c         1140 g         2566 t
ORIGIN      
        1 aattttttag catccactgc atttggaatc aaagtgaatt tatcatttcg aaacaaaaaa
       61 tcacctgcta cttttccaca tgaaaattca tgtgtcaaaa cagacgttaa cttacatcga
      121 taatattgct ttaaaagata tttaaaatct ctatctatcg atgtattatg gctatgtgct
      181 atccgtatcg gaatcccagc tttttttgca gcttttaaag gtaaataact catcgcatca
      241 atatgagaat gaacaatctc atattctgga tgatccttaa aaaattgttc catccattta
      301 aaatatttag gataattttg tggataaagt ctcggtgcat aatagacctt tcctccaaga
      361 cttattattt cctcatcata atcactttta tatggacgat gtgtcaaaaa atcaaactga
      421 attttagttc gatctatatt cctataatag ttcattagca tcgtctccaa ccctgcacga
      481 tgcatatcat tcacacactg taatattcga atcattatat atttccccta tacaaattta
      541 atgtttcttg tacgatttta tcccaattat atttactaca aataaactca gtagcttgat
      601 tcttcaaaac tttaaccatt tccgattgat tgcatgcctc ttctaatctt atctttaaat
      661 cacttacatc cgatttctta aaaatcatag ccttgtcttc tactacttcc gtacactctg
      721 agatatttga aactatacaa cagttcccat aactcattgc ttctaacaaa cttaatggca
      781 ttccttctaa atcacttgga agtgtataga tatacgcatt actatataat tcttctaatt
      841 cctgtccttg tacaaatcca gtaaatataa ttcgctcatc accttttgct aattccttta
      901 gttcatttgc aaattcatct gtatcagagc ttcctccggc tattataagt tttttatctg
      961 tctgaacatc tttaaatgcc tcaattagat accgaattcc tttttcggga accaatcgcc
     1021 ccaaaaacaa aatataagaa tcttttgtta atccatactt ttctgtaatc aatcctgctg
     1081 attttatttc aattttttta acgccatttg gtataaacct tgtttttctt ccatatatat
     1141 cttcaaaata attttggacg ctttcactaa gtacaattat ttcatctgca aattttacag
     1201 cacacttttc ccctaacatg atgtatgtac tagcaagctt gttccatttt tctctttgat
     1261 gatctagacc atgaattgtt gcaacacatc ttttcccaaa aagttttggc aaccacaaca
     1321 tagcacatgg tccttctgca tgaaaatgaa caacatcata ttttccgaat gctgctctaa
     1381 ttccaccaaa tactgaagaa ctcattgctg caattccttt tatatttaat gtaaaaatag
     1441 tctttaattt tacaccttta tattctttat ttttatgctg gtcaaattcc tttccgctaa
     1501 catgatgacc acttcgatta tagcaagtca cttcatgccc aagtgcaacc attcgcgttg
     1561 ccaattcttc taccactatc tcaattccac cttctcttga tggaattctt ttatgaccta
     1621 gcatacagat ttttaatttt tttcttgcca tcacgtttta ctccttctat agtatcttta
     1681 tcttacatgg aaccgtttct atgaagcaca gttttgactg tcctaaacaa aattctaaaa
     1741 tctaatccca tactccaatt cctgatatat tctgcatcaa gttttacaac ctcttcgaag
     1801 tctgtgatat cacttctacc actcacctgc cacattccag taatcccagg tttcatcgca
     1861 attctcgcac gatgatgaaa atcatacttc tcatattctg acttcaagca aggtctaaac
     1921 cccaccaggc tcatttttcc cattaggaca ttataaaatt gtggaaactc atccaatgat
     1981 gtagatcgaa taaattgtcc aattcctgtc ttctttgttc catcaggaag tattttattg
     2041 ccaatgattc ttgggtcaaa atccatctta aacatgagat tattactcat cttattttct
     2101 ttcatcaact ctgctttgcg ttcttctgca tccatataca tactacggaa cttatacatc
     2161 ttaaatgtct taccattttg accaatacgt tcttgtgcaa agaaaatcgg ccctggtgat
     2221 ttgatgtaaa taactggtgc tacgaagata aaaataacac ctgttgcaat acatccaata
     2281 attccagcaa gaatgtcaat cgttctcttt ataaatgctt gcctcatcgt cataacatta
     2341 atactagatg taataacagt ataatcacca actcggccaa taaattgttt tccacgtgta
     2401 ctatcagaca cttttgtaag attcatatgt acagcaagtc ccatttccga acatctggcg
     2461 attaattctt tgggatatgg aacactttcg tcaacattga tgaatacttc atctacccaa
     2521 ttctgtaaaa gatattccgc tgcattatca gcatttgcaa ctactgggac acctccgatg
     2581 gtagttccat acatatctct gtctactaca atcacaccac taagtttata catgccataa
     2641 ttcttctctt taagattacg aactacattt tttgcaatct tttgagatgt tacaataact
     2701 aacgatacat cttcaccgtt tttcatgcgg tgatgcaaca accctttcca aagtatacga
     2761 attatatatg ttaataatcc atacaccacc cccattataa ataaagaaac tctggaataa
     2821 tcatttccat cctgcattgt aataaggtat aaactgcaca caagtaacag cataaaagat
     2881 tgctttatag aagctacagc ctctttataa tatcctcttt ttaaaacatt tttatatgcc
     2941 tcaaataaaa atataatcgt aagattctca agttctataa aaattgccat gtggcgataa
     3001 ataggaatca catacggatt ccagtcaccc tgtcgcatta catatgatat ataaaaagca
     3061 agctggacac aaaataagtc taataaaata aaatcaatat gtttagacca accacttgag
     3121 ttttttctat acatctctca ctctctcctc atttcctttt tatctacgaa taaagaacta
     3181 aaataaacca aacttcttct tttttacctc ttcatagatt ggataattga tctcatcccc
     3241 gttgatcaga tcctttgcga cttgtttcat ctgtactact ttttccttac caaactcctt
     3301 ggcaatctgc tcatagcact cttttaagta aaaggtgcgc ttagagaccc cgtgtgcatc
     3361 agaagcagcc atctgcacga gattatgttt gaccattgtt ttggctgttt tctggatatc
     3421 tttgccaaat acaccaacat aacttggcgc agtaagttgg gccaaacatc ccatatctag
     3481 gaacggaagc aaatgatttg ggtcttctcg aaaatgcgcg ttgcgttctg gatggacgat
     3541 cactggtatc tttcctagtt ctaacaactc aaaaaaaagc cgttctgcat ataacggcac
     3601 ttccagtgtc ggaaattcga tcagaagata tgtatcatct aaatctgtaa ataaaatttc
     3661 atctcggtgg atgtcttcga tgagcgttcc ggtaatacgt acttcttgtc cttccaataa
     3721 cgtcaaaggc aactgtcttt tctctaattc ggcttgtaac gaagcgacta gagaaatgac
     3781 ttgtgatttt tcattgctgt attttccatt attgtggtgt ggtgtgcata aaatatgcgt
     3841 aatgccttgc tgaatcgctt tttcagccat tgcaatactt gcttctaagt tttctgcccc
     3901 gtcatcgatt cctggtagga tatggcaatg tagatcgatc atttctcttg tctcctctct
     3961 tcttattcct taatttccgt agtaataacc agcatctttg ctgtgttctg ctccgttgta
     4021 tacgacacct aagactcgtg cttgtaccat atctaacagt tcttttgctt tagtcaatga
     4081 ttcttttcgt gacgtatttt cccgtacgac caataaggtg ccatccgttt ttgaagacat
     4141 gatctgtgca tctgttacgg caacgactgg cggcatgtcg aagatcacta catcaaatag
     4201 ttgtcttgct tctgctaaaa tctgatccat tcttggcgaa cttagtagtt ctgatggatt
     4261 tggtggttta ggtccacttg gcagaatcga caaattgtcg actggtgttc gttggatctc
     4321 atctgctaca cttcctgatg aactaagaac agtacttaat ccgcttgcgt tgttcaactt
     4381 gaacgtttta tagatgacgg gcttacgtaa gtctgcatcg actagcagca cccgttgacc
     4441 agatttggca aaaacaacgg caatgtttgc tgcagtggtc gatttccctt ctccaggtcc
     4501 tgatgaagtc acaacaatcg ttttgatttg ctgaccagct gcggaggcaa actggatatt
     4561 cgtccgaatc gtacgatatt gttcagcgat tggtgaagag ggattggtga gtgtgaccaa
     4621 actgactgca tgagtttggg ctgctttttg tttctgtgtt cgtgccattt tctttcctcc
     4681 tagactcttg agcggcttct gcgtgatggc gctgttttat cgtttgtagc ttttggttgt
     4741 gtctgagctg gtcctttttt acggatacca gcattcaatt ctttcgctga catttctgga
     4801 actgttccta agattgggaa tcctaatgta tctgtcacat atttttcatc tttcactgtc
     4861 cgatcgagta attccaataa gaatgccaga cctacaccta ccatcattcc taacattaag
     4921 ccagtcatta aattcaattt attatttggc gaaacaggtg tcgtattggc aactgcacct
     4981 gaaatgatcg agattttatc aacattcatc acatcttttg cgttctcttg gaaaacttgt
     5041 gaagttgtgt tagcgatctg ttgagcagcc actgcattcg tacttattgc ctgaatcgag
     5101 aacatttgtg aattttctgc ctgattaact gagatggcat ctttgatttg ttcagcagtc
     5161 attttcacat tgtcttctgt ttctaaacga tctttgactt cattgagcac taaatcactg
     5221 acgatcatat ctttatacgt attgatcatt tgcaggttcg tattgacatc attgacattt
     5281 gcagtgtctg attgtggcag tgtcacgatc aattgtgctt gtgaactgta ttttggtgtc
     5341 aagatgaaaa atgttacgat tcctgagatg gccaagccag caaacattga gatgatgatt
     5401 attaccaagt gtttgcgtaa tgtttcaaaa atttctttca agctgattgt ctcttccatt
     5461 ttttctccac tttcctattt attctctaga ttcatttgat cttttaattc ttttttcaca
     5521 cgatcaagtt cttgatcact gactttttga taggagatat tatcttgcat gaagccttct
     5581 ccttgcagct gatcttgctt aatcgtacca aatgcctccc gataatctaa agcaattttt
     5641 ttcatttcat caaagttcat gtctgttttc atattcgact ctagagcatt caaaacggat
     5701 tgatagttgc tgacaccgtt tagactcaat acttttttcg ctacgccttc tacgatcttt
     5761 ctttggcgcc cttgtctacc gtaatcacca tttgggtctt cataacgcat acgagaataa
     5821 gataatgcct gatccccgtt caatgtaatt ttaccgattg gaaagtcata gccatcttgt
     5881 gagaaagtga ggtcattatt gacttcgata ccaccaactg catcaacgag ttcctttagc
     5941 cctttcatat tgatagagac atagtgatcg attgggatgt ctacatattt ttgtacggta
     6001 tccatcgcca tggcagctcc gccgaatgcg taagcgtggt tgatcttgtc ttttgtgtca
     6061 cgacctacga tgtcgacata cgtatcacga ggaatgctga cgatcgttgt ctgtttgtct
     6121 tcaggactga ctgtggcaac catcatcgta tctgatcttc cttgatcgac ccgacctaaa
     6181 tctccagtat caatccccat caatagaaca gagaaagatt cttgtttgtc cagatcaact
     6241 ggtttcgttc gttctccttg ggttcgttcc actgattcgt aagttttctc aatagaatgt
     6301 gagagatcca gatataattt tgctcctact cctacaattg ctaatactaa tacgataaga
     6361 actgctaaaa taatcagaaa tatttttttc cctcttgatt ttcttcttcg tcttgccata
     6421 gtttcctccg tttgctaacc ttgcttgaat caacgtttta actgtcaata gcttatattg
     6481 ctatagccca tttgctcagc aacagtttgt gcttttgttg cgtatgctgc gcttattttt
     6541 tcattccgga tctgctctat ttgactgagc accgtcaaat attgatcgta agtagcggtg
     6601 gcagtcactt gaccatcctt taacatcgta tcgaataact gatctagttg cgtgacttgc
     6661 gcgatctgaa tatcagcgaa tcctagatat tgcataacaa ccgttttcca aggactatct
     6721 ttaaaaaagc tcatattttc acgtacacga gcgacatctg cacttgtcac cttttctttg
     6781 atgatgacat cgtctacagc ttgctgccag tttgatacat ttttagtaaa taaatcgttg
     6841 acagctgtct ggatcttcag ttttgattct gcactatcta actgtgtcac gattgctttc
     6901 ttctcatctt ggattgcaac agcttcttta ggcaattctg attctttgat gtcgtaatca
     6961 tctgctgaaa gtttgacaga ggatagctta tttgacaaac ttgtgattgt ttcttctgtt
     7021 atttcagggt ttagaaaaat tttttctttt gtactataca gcttgtctac ttcttttgat
     7081 aaagaagtca aggtgtcttt ttgattggtg atggcagatt ctgcataatt gatccgttgc
     7141 tgatgttgcc gctgattatt gatatggtat ccaaacaaac agatcgcaat agcacctgca
     7201 cctaccgcca cagcagtcaa tgacttgacg aatggctttt ccatagattc actcctaag
//
LOCUS       DARBDN010000113         6924 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000113 DARBDN010000000
VERSION     DARBDN010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.116"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            94..1248
                     /locus_tag="SCH06_002454"
     CDS             94..1248
                     /locus_tag="SCH06_002454"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEG1078986.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(1270..2022)
                     /locus_tag="SCH06_002455"
     CDS             complement(1270..2022)
                     /locus_tag="SCH06_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEG1078987.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2386..5052)
                     /locus_tag="SCH06_002456"
     CDS             complement(2386..5052)
                     /locus_tag="SCH06_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEG1078988.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5393..6844
                     /gene="cls"
                     /locus_tag="SCH06_002457"
     CDS             5393..6844
                     /gene="cls"
                     /locus_tag="SCH06_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEG1078989.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
BASE COUNT         2044 a         1421 c         1252 g         2207 t
ORIGIN      
        1 aatccttaaa tattctcttt tttatatttc ttttaatctt tttatgatac cttagtaaag
       61 taagtttttt atcataagta aagaggtgtt gaaatgaaaa tagggattga tcgtctttcc
      121 ttttttattc ctaatttata tttagatatg acagagttgg cagaaagccg tggggatgat
      181 cctgcaaaat accatatagg gattggtcaa gaccaaatgg cagtcaatcg tgcaaatgaa
      241 gacatcatta cactaggagc aaatgctgcc agcaaaatcg taacagaaaa agaccgtgag
      301 ctaatcgaca tggtcatcgt cggaacagaa tccgggattg atcattcaaa agcgagtgcg
      361 gtaattatcc accatttact gaaaatccaa tcttttgctc gttcttttga agtaaaagag
      421 gcttgctacg gtggcaccgc agctttgcac atggcgaaag aatatgtcaa aaatcatcca
      481 gaacgaaaag tactagtcat agcaagtgat attgctcgtt acggcttggc aagcggtggt
      541 gaagtgacgc aaggtgtcgg tgctgttgcg atgatgatca ctcaaaaccc gcgtatttta
      601 tcgattgaag acgacagcgt atttctgaca gaagatatct atgatttctg gcgtccagat
      661 tatagcgaat ttcctgttgt tgatggtcct ttatctaatt ctacgtatat cgaatcattc
      721 caaaaagttt ggaatcgaca taaagaattg tcgggtcgag gactcgaaga ttatcaggcg
      781 attgctttcc atattccgta tactaagatg ggaaaaaagg cattgcaaag cgtattagac
      841 caaacagacg aagaaaatca ggaacgtctt atggctcgct atgaagaaag catccgttac
      901 agccgacgaa tcggtaatct ttacactggt tcattatacc tggggctaac ttctctactg
      961 gaaaattcga aatcactaca gccaggagat cgcatcggtc tattcagcta cggttctggt
     1021 gcagtaagtg aattttttac aggttatctg gaagaaaact atcaagaata tctcttcgca
     1081 caatctcatc aagagatgct agattctcga acacggatca ctgttgacga atatgaaacg
     1141 attttcagtg agacgcttcc tgaacacgga gaatgtgcag aatatacttc agatgtacca
     1201 ttttcgatta caaagatcga aaatgatatt cgttactaca aaatataata aaatcataaa
     1261 aagaaccctt cacgagtcgt gaaaggttct ttttttatct gcggaccaaa ggagcagtct
     1321 ataggtcagc ttagtcgtac taaggatttc tcgtttttca ctgaatagtt tgcgaatgta
     1381 cctggtcaca acaggatctt ttgcgtacgc gtcatagtat agcttcatca attcttcagt
     1441 aattgattcc tgtgtaaaat aagtaaaatc ttttttcttc actttgaatc cttcatcaat
     1501 taagtatgtt tcaaattgat ccattacaac tggcgatgta ttaggatctt cttctatcat
     1561 tcctagttgc ttttcgatag gataaaaaac atcatcgatt gattccacta ctctgattat
     1621 cacgcaccat ttgcttgact ttttcatcaa tttttctaat tgaataagat gtaccaatgc
     1681 tggatttgct gctgtaaaaa ccatttcata tgtctcattt gattggataa attcttctaa
     1741 cgactgtttg ataaaggaaa catttggcaa ctcatttttt tctgcttctt tttttgcatt
     1801 ttctagcatt cctgaagaaa aatcgatcaa atcatagcga ttaatttctt ttgctaagga
     1861 aagaaatctg ccagatcctc cagcaacgtc tgctgctgtt tcagcaggca ggactttctc
     1921 cgttttcaga taatttttta catcttcagc aatagttact tgcgattctt gctggatttc
     1981 ataatattct tcagcaaatt catcccattc tttttcattc atttgatttc ctctaatttt
     2041 ttgttatatg ttttcacttt tcggaataaa tcattctcct cttttatcta ttctatctct
     2101 tttgatgaat aataaaatga ttggctttcc gtctatcata aataaaaaaa gggactgtga
     2161 ccaaagtcgt gtcaaagtcc ctctttccga ataaacagtg tccaatcaga tgaccctcag
     2221 tattagctca aaatgctgat tttacaactt cttccttaaa cggtgttctc ctgccaactc
     2281 ttcggtcaca agtcacaata ttcaacaaac atgagaagct gtttgttgaa attgcacctt
     2341 gtgactcaga attaaacggc aggctcacaa cctcgttgat tcgttttatt tatttccttg
     2401 tactcgtaca atgatcaatt tagtgatttc catcaaaaca attgtcacaa gtgcgattcc
     2461 catacatgta aagacttctg tcaatccaaa tgctgatggg atagagaaga cttctttcag
     2521 tcctgggatc attgttaagc agtaaagcgc gctacataca actacagcta gtaagacact
     2581 tctgttagag aagaaccctg cttggatagc tgtttgtgtg tttgaacgtg ctgggaatgt
     2641 ttgcaatgtc cgacaccaaa tcaatgttga aaatgacatg gctacaccga attcaggtga
     2701 atgctgcatg ccaagccatt gagcaaagat aacagcaatc ccaatcagca caccacgata
     2761 cgttacagaa atcaatgttt tgtccgtaaa gattcctgaa tttggatctc ttggcgggcg
     2821 gttcatcgta gcaggttcag ctttttctgt acctaatgca attgctggca gtgaatcatt
     2881 gactaaattg atgaacaaca gttgtaatgc tgtaaatgga ttggaccagt cagcaactaa
     2941 ggcaaagatg atcgcaatga tcgcacctaa atttcctgca aatagataag aaatagcttt
     3001 cttgatatta tcaaacacat tacgtcctac ttctactgcg ctgacaatag aagcaaagtt
     3061 atcatccgtc aataccatcg ctgctgcatc ttttgccaca tctgtacccg ttcccatagc
     3121 aattccgatg tctgcttgtt tcaatgctgg tgcgtcattt acaccatcac ctgtcatagc
     3181 tgagatatga cctttatttt gccaagcacg aacgatacga attttattct caggtgaaac
     3241 acgtgcataa acagtgactt tttctaaaac ttcgtttagt tgatcttctg tcaattcatc
     3301 tagttccgtc ccggtcaaag ccaggtttcc ttcttcaaaa atcccgattt gttttgcgat
     3361 agcaacagct gttgttttgt ggtcaccagt aatcatgatt gttttgattc ctgcacttct
     3421 tgcttctgtt accgcctgag tcacttcagc acgtggagga tcgatcatag caagcaaacc
     3481 aacaaggatc aaatcgtctt catcttcaaa tgataaatca aaattatcaa gtggacggta
     3541 agcaaaagct agtacacgta atgcgcgtgt tgaaaaagct tcattttgct cttggaattt
     3601 tttcatcaat tcatccgtca tcggaacgac ttcaccattt agcaatactt ttttactgcg
     3661 ttggaagacg atatctggtc cgcctttaac aaacaagtaa tttttgttat caattgtgtg
     3721 tccagtagac attaattttc gatctgagtc aaaaggaagt tctgcttgtc ttgggtagtt
     3781 gtttcggatt tcctgataag gctggtttaa tttttcacta aagtcgataa acgctacttc
     3841 cgtagggtcg cccaatttag taccgtcttc actgatcgat gcatcattcg ctaaaacact
     3901 gatttcgatc aagcgacgtt cgtcagctgt ccattttgaa gggtcatttg tgaaatcccc
     3961 agtatcgcca ttacctaaaa agtagtcaac aactgtcatt ttgttttgtg tcaatgtacc
     4021 agtcttatct gtacagatga tacttgtcga accaagtgtt tcaactgctg gaagcttccg
     4081 aataatggca tgacgttttg ccattttatt cgttcccaaa gataacacga ttgttacgat
     4141 agactgtaat gcttctggaa tagcagctac ggctacggct acggcaaaca tcactgcgct
     4201 gacgatatct gcagtcatat ctcctgtacc ttctccaaga taaatacgaa acagttggat
     4261 acctaaaatc aataaagaca atgccaaaat agccaaactt agttttttac tgaatttatc
     4321 cagacctcgt tgtaacggag tgacttgctc agttgttgat tccaaaaggc cagcaacttg
     4381 tccgatctcc gtattattcc cagttgaagt cactaagaat ttaccgcgtc cgtaagttac
     4441 gatcgttcca ctgaatacca tatttgtacg atctccgatt ggtaccgtac ttgtgatatc
     4501 cgttacttct ttttctgcag aagtcgactc tcctgtcagc ataccttcat ctacttttaa
     4561 tgatcccgca tctagtaaac gtccatcagc aggtacataa tcgcctgcgt ctaacaacac
     4621 gatatctcct accacaagtt cgtttgccgg aatcgttttt tccttaccat cacgaatcac
     4681 tcgagcatcg ggcgctgaaa ggtttttcaa cgcttctaaa gaaccttctg ctttttttgt
     4741 ttggacaaca ctgattatag aattcaacat caatactgca aaaataacta agaattcgat
     4801 gtagtcaccc atgaccatct gaatcagtgc gacaatcagc aatacgataa ccattgcatc
     4861 tttgaaagtt tctaagaaca atttccaagt tggcttcttc ggcttttctt ttagctggtt
     4921 caagccatct ctttctaatt tttccttcgc ttgcgtggtg ctcaatccat cggttgagct
     4981 ctgcgtttgc tgcatcaacg agtcgatcgt ttctttatag accgcttgtt gtgcttgttc
     5041 cttgttttcc aaatttcatc ccccattttt tgatcttggc cctagtcctg tctgaaaaaa
     5101 aagagaccta agacaaatac gcatttgtct taggtctcac catttcatac aataccagaa
     5161 aaccatttgg ttaacttact gttgatatta tcgcaacaaa cgttgccggt tactccccta
     5221 aggagatatt caactgtact aatatcctac cttattaacc tacaaaaagc aactacttta
     5281 gcccgattta cctacatttt catgaaagga gtgaaaagta tattcacctt ggtaggcttc
     5341 tttcttctat catgctatac taatgttatt gtatgtaagg aggaacattt ttgtggtatc
     5401 tagtattata accgcccttt atctattaaa tgcacttatt gctttggtgg ctattttgat
     5461 caaaccccga gatgtagcag ccatttgggc atggctctta gtattgtttg cccttcctgg
     5521 ggtgggcttt gtattatatt tatttttcgg acgtggatta acggataaga aaaaattcta
     5581 tctccgacaa agtgacttga aagaattaga aaactttcag tcttttagag gagataccat
     5641 tgaacattac gatcctgaca tgggcgataa agacaaacag caatttgttg acttcttctc
     5701 ttcattaaat cgtatgccgc tgacaagaat gaattctgtc actcttctca cagacggaca
     5761 agagaaattg gattcactgc ttcaagatct aaaaaaagcc aaacattcga tccatatcga
     5821 atattacgca tttgtgacag ataatatcgg ccagcaagtc ttacatgttt tagaagaaaa
     5881 agccgcagaa ggcgtggaag ttcgaatatt atatgatgca tttggctctc atggcacaaa
     5941 agcaaaagat ttcaatcgtc taatcaaaaa tggtggacat gtccatacat ttgttacctc
     6001 acaaagggca ttacttcgtt tccgattgaa ttaccatgat caccgaaaaa tcgttgtgat
     6061 cgatggaaag attagttata ccggtggttt caatattgcc aatcaatatg taaatacaac
     6121 aaaaaaattc ggctattggc gcgatacgca tatacggatt ttcggtgccg cttcttcttt
     6181 gctccagctt cgcttcttaa cagactggaa cgtctcggta cctgaagaaa aaaaggtcgg
     6241 ctatcatttg aattatttct ttaaaaaagc agatcgagat gaatctaagc ttgctgatac
     6301 atccatccag cttgtttcaa gcggaccgaa taacgaaagg gaacaaatca agctttcatt
     6361 tatcaaattg attacttctg ctaaaaaacg tgtttggata cagacacctt accttgttcc
     6421 tgatgaaagt gtcattgctg ctttaaaaat cgcaactgcc tctggtgtag atgtgaaaat
     6481 catgattccc aacaaaccgg atcatccttt tatttatcga gcaacacaat attatgctcg
     6541 gcagctgatc aaggaaaatg tacaaatcct tgtctatgag aacggcttcc tccatgcaaa
     6601 aacattgata atggatgatg aaatctgcat ggtaggttca gcaaatcaag atattcgtag
     6661 ctaccgattg aattttgaaa caagtgctgt catttacgat cctgagtttt tagaagaact
     6721 tgctactcag ttcaaagaag atgagacaca ttgttcatcc atgacaactg aaacagtcaa
     6781 ggaaatgtct aactggctat tattcaagca acaaatttct cgattatttt ctccaatcct
     6841 ataatttttt tattcaagta gagaaaaata tactaagatt aaagggactg tgacaaaaat
     6901 cttgtcacag tcccttcttc cgaa
//
LOCUS       DARBDN010000114         6853 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000114 DARBDN010000000
VERSION     DARBDN010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.117"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..182)
                     /locus_tag="SCH06_002458"
     CDS             complement(<1..182)
                     /locus_tag="SCH06_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEG1078990.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="SCH06_002459"
     CDS             517..951
                     /locus_tag="SCH06_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEG1078991.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="SCH06_002460"
     CDS             974..1294
                     /locus_tag="SCH06_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078992.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="SCH06_002461"
     CDS             1435..1626
                     /locus_tag="SCH06_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078993.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="SCH06_002462"
     CDS             complement(1697..1954)
                     /locus_tag="SCH06_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HEG1078994.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="SCH06_002463"
     CDS             2112..2375
                     /locus_tag="SCH06_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078995.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="SCH06_002464"
     CDS             2399..2587
                     /locus_tag="SCH06_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078996.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="SCH06_002465"
     CDS             complement(2670..2855)
                     /locus_tag="SCH06_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078997.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="SCH06_002466"
     CDS             3070..3441
                     /locus_tag="SCH06_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEG1078998.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="SCH06_002467"
     tRNA            complement(3591..3663)
                     /locus_tag="SCH06_002467"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="SCH06_002468"
     CDS             complement(3709..4137)
                     /locus_tag="SCH06_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1078999.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="SCH06_002469"
     CDS             complement(4197..4955)
                     /locus_tag="SCH06_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEG1079000.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="SCH06_002470"
     CDS             5250..5447
                     /locus_tag="SCH06_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079001.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="SCH06_002471"
     CDS             5553..6035
                     /locus_tag="SCH06_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079002.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="SCH06_002472"
     CDS             complement(6093..6689)
                     /locus_tag="SCH06_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEG1079003.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT         2326 a         1056 c         1347 g         2124 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc cccagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agt
//
LOCUS       DARBDN010000115         6830 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000115 DARBDN010000000
VERSION     DARBDN010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.118"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            160..2835
                     /locus_tag="SCH06_002473"
     CDS             160..2835
                     /locus_tag="SCH06_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HEG1079004.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3017..3256
                     /locus_tag="SCH06_002474"
     CDS             3017..3256
                     /locus_tag="SCH06_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079005.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3272..4645
                     /locus_tag="SCH06_002475"
     CDS             3272..4645
                     /locus_tag="SCH06_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079006.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4649..6283
                     /locus_tag="SCH06_002476"
     CDS             4649..6283
                     /locus_tag="SCH06_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079007.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTNLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6446..6652
                     /locus_tag="SCH06_002477"
     CDS             6446..6652
                     /locus_tag="SCH06_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079008.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTG"
     gene            6721..>6830
                     /locus_tag="SCH06_002478"
     CDS             6721..>6830
                     /locus_tag="SCH06_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079009.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         2409 a         1101 c         1368 g         1952 t
ORIGIN      
        1 aaaagaaaaa agttgtgatt tccaaaatca caactttttt cttttgtcaa gattttgagt
       61 gggatatatt tttgtagaac tgaagatcat gaaattatga gaggttggag gtaatgtagt
      121 catacaaata aaaatttttt agaaagtgag tggtaattaa tgaaaatgaa tcacacttca
      181 attcagaagc atttacaact gttaaataca ctggggattt cttatgttaa tttgagaact
      241 ttttctacat taaacaagaa aaccgtttct catatttttt ctactgcaga ttctcaagca
      301 attattaact atttagaaaa acagaaattg tctgaaggta cagtaaacat aacttataat
      361 cctattaaac aagaggtgat tacacaaaaa aagcattctg tgagagacaa tgatattgaa
      421 aaaattcggt ttgtatttat tgatattgac cctaaaagga aagagggaag tgcaacagat
      481 agcgaaaaga aaaaggcaga aaatgttatg gaacaagtag aacgttattt gaaagaaaag
      541 agaatagaat catttgtaaa agttgatagt gggaatggct accatatttt tcttcccata
      601 aatgaacaac caaataatca cgagacgatt cttactattc agaattttct tcaattactt
      661 caccgaagat ttggagtaga agatgaagtt gatattgata cttctgttta taatccttca
      721 agattatgca aattagttgg tacaccagcg gtcaaaggaa agtccacaaa agagcgtccg
      781 catcgtttat ctagtttcct ttctattccc gataacatag atagaagtaa ttgttttaaa
      841 attcttgaac agatagttga agaaaattcc atgatgtcaa cctctagagt aaaaagccat
      901 ccatctttta gagaagtgtt accttttatt caagcagact ataaacaatg gttagctcac
      961 tatcctgaat taacttatac cataaaagag ggcgatcata aaggagttac cttacttata
     1021 tttgacgaat gtccattaag aaaacacacg aataattcta atggttcttg tttgtctgtt
     1081 acggctgata ataagattcg atttcattgt ctgcatgctt cggataaaaa taaagatatt
     1141 caagactttg taaaaaaata tccgttgcca aaacctgtaa atccttctgt agaatcatta
     1201 gaatccaatc aagaatatta ttttgaccag tttaaactga atcaagaagg agtatttttg
     1261 gtgaaagaag gtcaagaaga aaaagttgct tgtccgatgt ttattaagca aatacgcaaa
     1321 aatatcgaac aaaaagtcat tacacttgtt cttgcctatt atgtcgatca ttgttgggat
     1381 gaaatagaaa tagaaggtgg atgtttacaa actaataatt ttaaacaatt agcaaaacat
     1441 ggcttaatca ttaaagctag aagagaagct gaagtcgttg actttttaca gattcaacgg
     1501 gagaatgctc caatcttttt tgaacatgaa tctcttggct ggaaaaaaga aaatgaagca
     1561 atgatttttc agttacaaga ttcttttgga cgtgaaattc cttctgtatt aactaaaaac
     1621 tcatgctacc aattaacaac taatggtaca gaagcggaat ttgacgcatt ggttcataag
     1681 tatgttttag gaacgaactt agaacttgct tggtcgattg gtattgcttc tattgtgtta
     1741 ggctatttaa acgttacgaa ggctaatact tttttgagtt tactaattaa cctacagggc
     1801 aagagcacaa cgggtaaaac cactacgtta cactttattg cctctttatt tggaaatcca
     1861 actacggttc ttagaaatat gaatgctacc aataaagcca ttataaagct agcatcaaac
     1921 aatcagggag gtgttccact aatactagat gagttaggag cagcaactca aaataacttt
     1981 agctcgttga tctatcaatt agcttcagga gaagaaaggc taagattaga ttctaattgt
     2041 cagcttatgc cacaagagac tttttctgtt ttgaccctta cctcttctga agagcgtttg
     2101 gaaaattatt tcaatgagaa attaactggt ttgaaagttc gatatatcga attttctgat
     2161 atcaagttta caaaggatgc gaatcacgca gagaaagtta aaagtctttc ttctaatact
     2221 tttggttggg gtataaagtt atttcttttg aaactctttg aacaagggat tacaaaaatt
     2281 gaagcaactt ttgtcgaagc tcaaaaaaaa ctatgggctg ttttacctga acattctttg
     2341 aagcaacgca ttggtaataa tctagctttg atttatagtg gagccctcct aattcaagat
     2401 atactgggct atcctttacg attagagcat atacagacgg tgcttattaa ttcgtacgaa
     2461 cagttaattg tagatactag tttaggaagt gagcaaacgg tatttgaccg agtgaaaaca
     2521 ttgttggtga tgaatagcca taaattttta acaaacagtg acaacaaaca tacgcccagt
     2581 acgatttggg gaaaagtatc aattcaaaaa aatggggata ttaaggtaaa tatttttcct
     2641 atcccgtttg aggacttgtt aaggcgagaa tttcaagtaa aggatctaac ctatcttttt
     2701 aggcaattgc ttgattcggg taatatgtgt gcagaaaaag ggagaagaac gaaacgtatt
     2761 cacatgaatc gtcaagttct tccaacatac gagattctat taccttcttc actcaaatcg
     2821 tattttcgat tgtaatttag aataaaccaa agtatgaaag tgaggcacca tgttatggaa
     2881 atatttctta ttgatttagc aaaacaactg attacttatc tgtatgatag cgagcaaacc
     2941 caaacggaag taaatgaagc ttgatctatg cttcatttac ttcattcaat caaacatgaa
     3001 agaaaggaaa attctaatga ctaaaaataa aatgacacta aaagcagagg ttcttctgta
     3061 tattcaagaa catttttcaa atcaagcctt ttttacaaaa ccaatttact tggatttcga
     3121 aataagaggg gtatctgctg gatctatcgg gggtactctt caagcgttga agaacgaagg
     3181 atatttagaa aatcactttg tgcaacgttc gttcaataga agagtcgtga aaaaatggta
     3241 tttagttcat tcatagagag gggaatcaag catgcgtgtg gcttgttatg atcgaacgtc
     3301 tgtttatgaa gaagcgaaaa ttagtaatga cgctcaatat gatgcagtga aagagtatgt
     3361 tttagagaaa tatgaacaaa ttccccaacg attttcagac aaaggagaat caggggaaaa
     3421 agcggagcgt ccagcttttc gacagcttag agcttgggtt tgtgcgtcag aagaagaggg
     3481 ggtgatctat gtttggcgtt atgatcgatt ggcacgtcaa gccaaaatag ccttagaatt
     3541 tattgagttg tgccaacaac atcaggttca agtgtattcg atttctgaac ctcttcctgc
     3601 ttctttctca cacgcgtcaa cgaataaact atttgtgcaa ttattgttca cttttgcaga
     3661 acaacaacga aacgtcatta ttgagaatgt tcgtgccgga ctttcctata aaaagcaaca
     3721 acggcaatat ttgtcttctg cggtaccata tgggtatcgt ttagtgaatg ggaaaatcca
     3781 acaagaagta cacgaagcaa ggattgttcg ctatattttt caactttatt tgaccaaaaa
     3841 atatggctac aaaaagcttt gtcaacgatt gacgcaacaa aagcttttct tccgcgaacg
     3901 tccttttcag ccctatcata tttatagtat cctaaaaaat ccattgtact atggcgaaat
     3961 caaaggagga tctttgggga agtatctagg aacctttgaa ccgattctct cgaaagcaac
     4021 ctttttacaa gcccaagaga ttcgccaatc aaggtgtaca gctaaaaaag atacgtatct
     4081 gtacttatta cgtcaaaaaa ttcggtgtcc cttctgtggt cgtcatctga gttcgaagta
     4141 tcaatggaat acaaagaaga cgaagacgct tcattattat cattgtaccg accgaagctg
     4201 ccaaggaatt tttcttcggg cagaaagggt tgagtcagaa gtattggaaa agatacaggc
     4261 tttttttcaa tacgaaggcg tctatcaagc cttgattgcc caattaacgc aacaattagc
     4321 cgaaaagcga aaagatgaaa aacgcaaagt aatccaacaa aagaaacaag aagcacaatg
     4381 gattaaggca tttgaagagg gcaattgttc actggaagaa ctcaagcaac aactgcaagc
     4441 tcttcaaaag ccgatgtcta cttcttcgtt tctttcactc caacagtgtg aagcaaaagt
     4501 gaaagaatgg cttcaactaa aagacctctc tagtcgacaa ttattatgtg actatgtttg
     4561 tcggattgag gtaacaaagg ataaaacagt ttgtgggatt tacttccgac aactgacaca
     4621 aaatatttta gaaaggaacg aatgatctat ggaaatgata caaaccaaac gagtcgcatt
     4681 gtatattcgc gtgagtacac aagaacaagc tttagaagga catagtattc aagcacaaga
     4741 acaaaatgga cgacagtttg ccgaacggat gggctatgaa gtggtagaag tttatgccga
     4801 tgaaggaatc agtgggaaat ccacaaaaaa tcggttcgcc tatcaacgaa tgatgaacga
     4861 tgctcggaac catcgttttg atctactagt gatttggaaa ttgacccgtc tcggacgcaa
     4921 tatgttagat gtcttacaaa cagtcgagga attattgcga tatgacgtag gattacattc
     4981 gatctcggaa caatttgacg tgaccacttc gacaggtaaa ttgatgttac aactccttgg
     5041 gagtttcggt gaatttgaac gcaaccaaat tgcggagaat gttcaaatgt caatgcaaag
     5101 cttagtgaaa gataaaaagc gttatgcagg aggccgacgt ttaggctatg tcagtggtat
     5161 tgacacgaat ggtcaaaaac aattggtcat tgaaccagaa gaggcgaaaa ttgttcgtct
     5221 gatctatgca aaatatttag gcggagcagg gtatcgagcg attgccaatt ttttgaatcg
     5281 tcaaggatat caaacagtca aaaagaatgc tttttctacc acggcagtca aagatatctt
     5341 acgcaataaa atttatgcag ggtatttaga atatgcgcgc tacatcaatt gggaaaccaa
     5401 acgacggaag gggaagaatc cgagaccgat tttagtgaaa ggaacccatg aaccgattat
     5461 ttcggaagaa gattatcaaa aagtacaaga acgccttgct ttagaaggaa aacaacccaa
     5521 atggaaccat acaggtgaaa atgtattgac aggcttgtta cgttgtccag aatgtggcgc
     5581 accgatggca gcgagtaatg tcacaaatac cctaaaggat ggcacaaaga aacggattcg
     5641 atattattct tgttcagtct ttcggaataa aggagcaagt gtgtgtcatg ccaattcgat
     5701 tcgtgccgaa caagcggaaa catttgtcgc cgaccgatta aaggagatcg ttcagctacc
     5761 agaagttctt ccccgattgg tggcagcgtt aaatgaagaa atagtgcgac aaagccaacc
     5821 attggaacaa gaactcgtgg tgttactgga acgaaaggaa gaattgaaga ctaaaattga
     5881 aaaatgggaa gctgctttgg aagatagtcc tgaattgttt ccgatgttaa aagaccgctt
     5941 agacgaattg actgaaaaac gacgacagtt gcacattcga gaaaatgaaa tcttagggat
     6001 ctttcaacaa ggagagccga ttcaagtcaa agatgtccaa cggatattga ctaatttgga
     6061 tcgttttctt gcccagagtg agaagaagca aatcaaagcc ttgtatcgta cctttataga
     6121 gaaaataacc tttgatccta accataagga gatgttggaa attacgatga aattcacgca
     6181 tgccgtggta caacaattga atgagcaata tcaaatagcc gtatccaaaa caaaggatac
     6241 ggctattttt gtgttaaaaa caccctttac gttaacgatc tagtctaggt tatatcaaac
     6301 aacgttagag gggcgctaac gcttctctag cgatttgaaa tcgttagaga agtagttagg
     6361 gaggtcctta tcataaatag ggatatttat taatgaatat ttgaaatata attgtatata
     6421 agaattaaaa agagtgggga tagatatgaa aaagatgggt aagtgtattt tatgtgaaaa
     6481 atacactgaa cttactaaag aacatgtacc acctaaaaaa tcagggaata ctggaggtaa
     6541 aaagaccaga actggtaatt tagatgattt ccttaagagc gattttacaa aaggtgattt
     6601 tccgaagggg attaaaagga aacctcaagg aaatgtttat tatactggat aggctacaat
     6661 taactagaca gaaaaattaa ggtgtgtaga ctagaagaaa acataccagg aggaattttt
     6721 atgtctaaga gaacacgaag aactttttca caagaattca agcaacaaat cgtcaatctt
     6781 tacttagctg gaaagccacg tgtagaaatc attcgagaat atgaactaac
//
LOCUS       DARBDN010000116         6643 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000116 DARBDN010000000
VERSION     DARBDN010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.119"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(1..859)
                     /locus_tag="SCH06_002479"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="SCH06_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="SCH06_002480"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="SCH06_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEG1079010.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="SCH06_002481"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="SCH06_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="SCH06_002482"
     CDS             complement(2603..3421)
                     /locus_tag="SCH06_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1079011.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="SCH06_002483"
     CDS             3582..4271
                     /locus_tag="SCH06_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEG1079012.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="SCH06_002484"
     CDS             4285..5787
                     /locus_tag="SCH06_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1079013.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="SCH06_002485"
     CDS             5800..6276
                     /locus_tag="SCH06_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEG1079014.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="SCH06_002486"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="SCH06_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DARBDN010000117         6600 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000117 DARBDN010000000
VERSION     DARBDN010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.120"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..486
                     /locus_tag="SCH06_002487"
     CDS             <1..486
                     /locus_tag="SCH06_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079015.1"
                     /translation="LIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLKDESNTTVSD
                     ANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKTGADIDHFDK
                     ALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQETIKKLRIG
                     G"
     gene            493..1344
                     /locus_tag="SCH06_002488"
     CDS             493..1344
                     /locus_tag="SCH06_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEG1079016.1"
                     /translation="MADNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDI
                     QSFIGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEK
                     DIENVTPSKKSKAKPVRHKYGEYKNVLLSDEQMEKLKIEFPNDYQERIERLSEYCESS
                     GKTYKNYLATIRSWARKEKSEPKNASGAYKRTGRREKLPEWAIDQEAYLKKKALERAN
                     RQSKAPF"
     gene            1356..1625
                     /locus_tag="SCH06_002489"
     CDS             1356..1625
                     /locus_tag="SCH06_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079017.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            1630..1794
                     /locus_tag="SCH06_002490"
     CDS             1630..1794
                     /locus_tag="SCH06_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079018.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            1787..2089
                     /locus_tag="SCH06_002491"
     CDS             1787..2089
                     /locus_tag="SCH06_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079019.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            2086..2397
                     /locus_tag="SCH06_002492"
     CDS             2086..2397
                     /locus_tag="SCH06_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEG1079020.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            2394..2612
                     /locus_tag="SCH06_002493"
     CDS             2394..2612
                     /locus_tag="SCH06_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HEG1079021.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            2623..3438
                     /locus_tag="SCH06_002494"
     CDS             2623..3438
                     /locus_tag="SCH06_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HEG1079022.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            3577..3933
                     /locus_tag="SCH06_002495"
     CDS             3577..3933
                     /locus_tag="SCH06_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HEG1079023.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKAHSIQHGFI"
     gene            3920..4138
                     /locus_tag="SCH06_002496"
     CDS             3920..4138
                     /locus_tag="SCH06_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079024.1"
                     /translation="MDLYDIESGATVSVESDHLIISFADERQIIIWVVDDMLYPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSK"
     gene            4135..4533
                     /locus_tag="SCH06_002497"
     CDS             4135..4533
                     /locus_tag="SCH06_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HEG1079025.1"
                     /translation="MIPKFRAWDKRENTMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLG
                     HRNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            4530..4868
                     /locus_tag="SCH06_002498"
     CDS             4530..4868
                     /locus_tag="SCH06_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079026.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            4865..5095
                     /locus_tag="SCH06_002499"
     CDS             4865..5095
                     /locus_tag="SCH06_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079027.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            5102..5305
                     /locus_tag="SCH06_002500"
     CDS             5102..5305
                     /locus_tag="SCH06_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HEG1079028.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASETIRKFGISILNDDRKWEAER"
     gene            5302..5607
                     /locus_tag="SCH06_002501"
     CDS             5302..5607
                     /locus_tag="SCH06_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079029.1"
                     /translation="MKLKDGFYTDAYGIGGLMMDLPTKNPIKQEESEIKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVINNGIKN"
     gene            5591..5884
                     /locus_tag="SCH06_002502"
     CDS             5591..5884
                     /locus_tag="SCH06_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079030.1"
                     /translation="MELKIDKVTFEEPAFQEMDERIAELVEKKQDELIALLEKKYQFP
                     KYMNKMQAAKYLGVSYNTMMDKYVPAGLKMGIVNGVIRISKEECDRFMKEHQK"
     gene            6144..6560
                     /locus_tag="SCH06_002503"
     CDS             6144..6560
                     /locus_tag="SCH06_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEG1079031.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
BASE COUNT         2470 a          969 c         1497 g         1664 t
ORIGIN      
        1 ctcataggcg atattttcat cgatacaggc atgccaacgg acttctggaa ggaattcttt
       61 tacttccgct ttgaaggtgt cacagggcgc aaaataagcc tcaaagatga atcgaatacg
      121 actgtgagtg atgctaacgt cttagcaaat atcatcttag atttcatctt tgaacatcat
      181 attcctttca aagaaggcta tgagatttta ccagcgaatc aagaatatta cttctacaaa
      241 tgcatcacaa aaagagtctg ttgcatctgt ggcaaaacag gagctgatat cgatcacttt
      301 gacaaagcgc taggaagacg aaagcgcaaa gaagttgatc attcagagta cacatttgca
      361 gcactctgca gaatccatca cacggagaaa cacaagatag gtgtgatcaa tttcaaaaat
      421 aaatatcaaa tcaaagggat caagttaaac caggaaacaa ttaagaaact tagaatagga
      481 ggataaaaaa tattggctga caacaaacga tactactatt taaaactaaa agagaacttt
      541 ttcgatagcg acgagatggt tcttttagaa agtatgccag atggatacat ttattctaat
      601 attcttctca aactttattt aagaagtctg aaacatgaag gcaaactaat gtttaatgac
      661 aggattccat tcaattctac aatgcttgcg actattacaa gacactctgt gggagttgta
      721 gaaaaagcag tacaaatatt tcgtgattta caacttattg aggtattaga taacggagca
      781 atttatatgt ctgatataca aagttttatt gggaaatctt caactgaagc tgataggaag
      841 agaaaataca gaaaagaaat tgaggaagca aaacagaatt taataacaag tggacaaatg
      901 tcggacaaat gtccggacaa aactacacca gagttagaga tagagttaga gaaagatata
      961 gagttagaga aagatataga gaatgtaacg ccttcgaaaa aatcgaaggc taagcccgtc
     1021 cgtcataaat acggagagta taaaaatgtt cttttgtcag atgagcagat ggagaaactc
     1081 aaaatagaat tccctaatga ctatcaagaa cgaatagaac ggctatctga gtattgtgaa
     1141 tcatctggta agacttataa aaactatttg gcaactattc gaagttgggc aaggaaagaa
     1201 aaaagtgagc ctaagaatgc aagtggtgca tacaagcgca caggaagacg agagaagctt
     1261 cctgaatggg caatcgacca agaagcctat ctcaagaaaa aagcgctaga acgagctaat
     1321 agacaatcaa aagcaccatt ttaagaggtg gaaaattgaa aatcgattat ctagaactaa
     1381 ttaatgaaat agcaaagtat aaaactggtg aggaaataga aatcctgaga gacgtatatg
     1441 atcaactcga agaagctgga atcgaaggaa ttaataatga tcgttcgagt tggagtaaac
     1501 tcagatacta tttcgcactc tatatcgata caacacaatt aagaaattta gcttatacaa
     1561 aattactatt tgttgattgc gttaaaggat tgcaaaaaca tcttagtgaa cttgagcagg
     1621 tgtaatcaga tggatctaaa aacatttaca gcacagatcg aactaatgca tcaagaagct
     1681 ttaagacaaa gcgcctcgta cgaagacaag tggctcaaca cgttccatgg tggacgtgag
     1741 agcgcacttg atcaagtact caaattattg aaaggggaac gtcgggatgg ataagaaagc
     1801 ggcaatgaaa cgaatcatcg aactgacaca ttctgagaat tggcaagaag acaaagaaat
     1861 agttacagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccca aacggagaac
     1921 gccgagaaag attgcaattt ggcatggtga tcgaattcta gtaacaggta ctgctgaaca
     1981 gttatctgaa attactggtc tgagcaaaaa catcatctgg gatagagcaa ggagcttatg
     2041 gattgattca aaaggacgac aatttaggta tgtggaggag aaaaaatgaa cgaactaatc
     2101 acaaaagtag agcagtgggc taaagacaag ggactggatc aagcagatcc aaaagcacag
     2161 tttttgaaag tagctgagga attcggggaa atcgcttcag caatggcaag aagtaatgat
     2221 gagctattta aagatagcgt aggagacgta atcgtcacgt tgattatcct ttccatgcaa
     2281 aaagggacaa acgtacaaga gtgtttagaa atggcataca acgaaatcaa agggcgcaca
     2341 ggaaaaatgg tagatggtgt attcgtgaag tcgagtgatt tggaggacag caaatgatag
     2401 gtttaacaat attttggtgt gcgattggtg gtttactagc atttctagga tactacctca
     2461 tctgtgaaag tagaaaagga agaaaatata cagtgacagg tattgtcctg ttaattatcg
     2521 gaattctagt tgcagttgga gcagaactga atctttatgt aaatggtaca caagaagatt
     2581 tggtgcgatt tatgttttgg atgaagaatt aggaggaaaa aaatgaacga aaacaaatta
     2641 atcaaattag gtgtagcagg agcagtaatc gtaggtattg gagttatcgg aggatttaag
     2701 ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa cggcggtatc
     2761 aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt gatccaatat
     2821 ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag cgacggcaaa
     2881 aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc agcaaaaatg
     2941 tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt aaaatctaag
     3001 cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt cctttcagga
     3061 gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt tgaatctaaa
     3121 gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga aacacaaaaa
     3181 tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct agatgcagaa
     3241 actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc agaagcagag
     3301 gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg ttatgaagaa
     3361 gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac tgtagttacg
     3421 gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt tcttaggttt
     3481 agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca aagaagatga
     3541 caacaacgat gaaatgaaat tttaggagga gaaataatgg atctcattac acaatacagt
     3601 gatatcatcc tcaagaaaat catggcaaag attcagaaag ataaaaaagc aaaagaacga
     3661 gcggaattag ttaagttgga aatggctgaa acaggagtag gagtgcgaag tagcaggcat
     3721 tggaaagcag cagcaaacat tgaattttat tacaacgaaa ttcaaaaagg gttcgatcag
     3781 atgcgtgagc tggatcggca aacaaattgg agcaagaaac ttcatcaaga tcgtttcaaa
     3841 tttgtagaga agtataaaga aatattagaa gagtatttga ggaggacagc gaatgataaa
     3901 aaagctcatt caattcagca tggatttata tgatatcgaa tcaggagcaa cagtatctgt
     3961 ggagtctgat catttaatca taagttttgc tgacgaacgt caaattatca tatgggtagt
     4021 tgacgatatg ctatatccag aaattgtaca tgattttgaa gaatcaaaag cggttgagtt
     4081 tgaaatagtg aaaaaagtaa tggaattgat tgaaaaatac gaggaggaca gcaaatgata
     4141 ccgaagttta gagcgtggga taagcgagaa aacacaatga gagatgtagc tgtcttacat
     4201 tttactaaaa acggcaaaac aaactttatt gaatattgga taaatcctac cgaattgaaa
     4261 tcatatcacg tgcgaaacat cgacctcatg caatccacag gaatgaaaga taagaatggt
     4321 gtggagatat ttgaagggga tgtagtaatt acatcaaaag gagcgattgg atatgttgcg
     4381 tatcttcaac aagaagccgg ctttgtagtt gtactaaaga aaagtgatta tagattaggc
     4441 cataggaata ctggcgaaag ttatgatgta gcaactgctc atgaagtcat cggaaatata
     4501 tacgagaata gcgagttatt ggaggtagag tgattatctt agctactgac tacatcgatt
     4561 ctttaaaaga tgaaaatggg aatgtcccag cattgctaaa ttgtggaatt aaaagcaaga
     4621 atagaatcat tttgttacgg atatcggctg atttagcaaa atatctttat ctgagcaaga
     4681 cagcagtata ttacactgcg gctacacgtt atcagtacaa gggaaaaaca atcagtcagg
     4741 attattatga tcgtttaatc agtcctgaca tgcatggaaa atcaaaatca gcgatcaagt
     4801 tatttggcgc aatagagata tatgccgatg attttccaaa tttatggttg aaggaggaag
     4861 cggaatgaaa tacgaaatac cactaagtga agcgggcatt caagcaatta tcaatggtcg
     4921 ggaggttaat aaaaaacttc ctgatggtac tgaattagtc atcagacaaa gttatttgaa
     4981 agatatggca gctccagtat taattgatcg ttttaacgtg actgattctg tggtagagaa
     5041 ccacttgaaa gaatttcgat caagtataaa cgacactttc agattaggga gttgattgac
     5101 aatgaacacc agacaccgca gagtagcaaa actaagaaaa caggaactga atgtactaaa
     5161 gacaaagttt gaaaaagaat atggaatttc agcagaagaa acatataaag tggcaagtca
     5221 gtttgttgct gatgcgagtg agactattcg taagtttggg atttcgatat taaatgatga
     5281 tcgtaaatgg gaggcagaaa gatgaaacta aaagacggat tttacactga tgcttatgga
     5341 attggtggtt tgatgatgga tctaccaact aagaatccta taaagcaaga ggaatcagaa
     5401 attaaagtcg gtgacatggt tcgctgcgaa gcagaagggt tcatctatcc atttcgtgga
     5461 tatgtagagc atctctataa tcactcagcg atcattcgta ttgaaaacac aatggaatgc
     5521 gataagtggt tagcgaaaag caaagagaat ttagcagtgg tgagattggt ggatatggag
     5581 gttataaaca atggaattaa aaattgacaa ggtaacgttt gaagaaccag catttcaaga
     5641 aatggatgaa cgaattgcag aattggtcga gaaaaaacaa gatgaattga ttgctttgct
     5701 agaaaagaaa taccaatttc cgaaatatat gaacaaaatg caagcagcaa aatatcttgg
     5761 tgtaagttac aacacgatga tggataagta cgtaccagct ggtttgaaaa tgggtatcgt
     5821 taacggcgtt attcgtatca gcaaagaaga atgtgatcgt tttatgaaag aacatcaaaa
     5881 ataaaataaa aaaacgttta gccccttagc taaacgcaca attataattt acctgacagt
     5941 taattataac aaaattgcgg aggttgagga atggcggaat gaaaaagaca ataaaaacag
     6001 aagaagcata tattgaagta tttgacacac cagcatgcta agtcgagaag tgtaactcgg
     6061 caaataaaaa aagccggatc gctccgactg atgtaataaa cccaacaagt ttattatatc
     6121 acataaagga gcggtttgac ttgatgcaat tgttacgaga ggtagatttc aaacagacaa
     6181 gatgcaatgc gagagatgtg ctgaagaatt ttcgacgctt agagcggatg gcaggtcgct
     6241 ctttgataga tattaagtcg ccgattatta cggatatgcc gaaggcaccg aagcacggca
     6301 ataaggcaga ggacgcgatt attcagatga tggatataga agcagagaga gatgcgattc
     6361 tagcggcttt gatggctctt agtctgatta gccgtcagat actctattat agcttttgtg
     6421 acgtaaacaa gcactctaat tatgaaatag ggcaattgat acgaggatac ggagagaaga
     6481 atgtagagaa gctgaaatct atcgcgctga tcgaatttgc tgaagcatac aaaaaaggcg
     6541 tattagttca gtatcgttga ttttgtaggg tttttgtagg gatagtgtag ggtttttgag
//
LOCUS       DARBDN010000118         6570 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000118 DARBDN010000000
VERSION     DARBDN010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.121"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            127..579
                     /locus_tag="SCH06_002504"
     CDS             127..579
                     /locus_tag="SCH06_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079032.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="SCH06_002505"
     CDS             593..1282
                     /locus_tag="SCH06_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079033.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="SCH06_002506"
     CDS             1407..3758
                     /locus_tag="SCH06_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HEG1079034.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="SCH06_002507"
     CDS             3838..4233
                     /locus_tag="SCH06_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079035.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="SCH06_002508"
     CDS             4558..5175
                     /locus_tag="SCH06_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079036.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="SCH06_002509"
     CDS             5216..5515
                     /locus_tag="SCH06_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HEG1079037.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="SCH06_002510"
     CDS             5549..5716
                     /locus_tag="SCH06_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEG1079038.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6366)
                     /locus_tag="SCH06_002511"
     CDS             complement(5761..6366)
                     /locus_tag="SCH06_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079039.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2265 a          910 c         1285 g         2110 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttccat
     6301 cattgccaat tgtcgatcca aattttgatc ttgtgaagat actcgaatat agccaatttt
     6361 tcccataaaa aactcctttt taaaagtgat ataatttaca tgtaaaattt acttgtagtt
     6421 ttactgctat catagcattt ttaaaaataa attttatgta gacttaaaat ttacttcatg
     6481 gagggtttaa atggatgaaa tcaaaagtaa caaaaaagca tttggcattt atttaggaga
     6541 acctagtaca gaacaattaa accaattttt
//
LOCUS       DARBDN010000119         6509 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000119 DARBDN010000000
VERSION     DARBDN010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.122"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(45..1421)
                     /gene="trmFO"
                     /locus_tag="SCH06_002512"
     CDS             complement(45..1421)
                     /gene="trmFO"
                     /locus_tag="SCH06_002512"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HEG1079040.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(1390..3468)
                     /gene="topA"
                     /locus_tag="SCH06_002513"
     CDS             complement(1390..3468)
                     /gene="topA"
                     /locus_tag="SCH06_002513"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEG1079041.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(3590..4447)
                     /gene="dprA"
                     /locus_tag="SCH06_002514"
     CDS             complement(3590..4447)
                     /gene="dprA"
                     /locus_tag="SCH06_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEG1079042.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(4503..5270)
                     /locus_tag="SCH06_002515"
     CDS             complement(4503..5270)
                     /locus_tag="SCH06_002515"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEG1079043.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(5263..6123)
                     /gene="ylqF"
                     /locus_tag="SCH06_002516"
     CDS             complement(5263..6123)
                     /gene="ylqF"
                     /locus_tag="SCH06_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEG1079044.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT         1661 a         1433 c         1151 g         2264 t
ORIGIN      
        1 aaaaagagcg agactatccg tctcaccctc ttcatggagt ttccttactc atttgggatt
       61 gcagtttttt ctaattctgt ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt
      121 gcttcatatc ttgctttttt gtctcgaatg cgctctggca gttcaggaaa cagaccatag
      181 ttggcattca tcggttggaa atgttttcct tccgcatgag taatgtagta agccatactt
      241 ccaatagctg tttcttgtgg aaactcgact ggttccattt cttttgctaa gcgtgcggcg
      301 ttgattccag caagtagtcc gctcgctgca ctttcaacat agccttctac accagtcatc
      361 tgacctgcaa agaacagatc ttcgcgtttc gttgattggt aagtcggttt cagcaattct
      421 ggcgaattca taaagctgtt tcggtgcatc acaccatagc gaacgaattc agcattttct
      481 aacccaggaa tcatccggaa aacacgtttt tgctcgcccc atttcaagtg agtctgaaag
      541 cccacgatgt tgtataaaga agctgcagca ttgtcttgac gcagctggat aacagcataa
      601 ggacgtttgc cagttttagg atcttccaat ccaactggtt tcataggtcc gaaaagcatc
      661 gttttgaatc ctcgctgtgc cattacttca attggcatac atccttcaaa atatttttct
      721 ttctcaaaag atttaagttc tgccacttcg gcattgatta gtgcctcatg gaaagctttg
      781 aattcctctt ctgtcatcgg acagttcaag taagctgctt ctcctttgtc atagcgggac
      841 ttcaaatata ctttatccat atcgatcgta gctttgtcta cgattggtgc agctgcatca
      901 tagaaataaa aaccatctga accattgaat gctttgatgc tttctgctaa tggatgagaa
      961 gtcaaaggtc ctgttgctac tacggtgatt ccttccggta tttcagtaat ttcttcgttt
     1021 atcactgtta ctaatggatg ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg
     1081 cggtcaacag ctaaggcacc accagctggc actgctgttt catctgccga agtgattact
     1141 accgaattca atcggcgcat ttcttctttc aataacccta ctgcattagc caaactgttt
     1201 cctcttaatg aattggaaca tactagttca gcaaaattac ttgtgtgatg cgcctcagtc
     1261 gatttgactg gacgcatttc atataaacgg acagggactc ctgcttgtgc gatctgccaa
     1321 gcagcttcac ttccggcaag ccctgctcca acaacattta ccattttcaa tgaaagaacc
     1381 tcttttctat tatttttgga tgtcttcttc gtaatctcca tttacacaga ctacttgttt
     1441 accgcctttg actttcttct cgaccagata tccgtcacat tttggacaat ttctgcccac
     1501 tggtttatcc caagaagtga attcacattc tgggaaacgg gaacaaccat agaatagtct
     1561 gtttttctta gattttcgtt caatgacttg tccttcatga catactgggc aagtcacacc
     1621 gatttctttt acgattggtt tcgtattccg acaatcagga aaattactgc aagcataaaa
     1681 cttcccatat ttccctaatt ttatcaccat cggatgtcca cagacatcac aatcgaatcc
     1741 tgctggttca tctttgattt gaattttttc gattttttct tccgcattcg tcagttcttt
     1801 ttcaaacggt ttatagaaac gatcaaccac tttgacccac gcttccgtgc cttcttcaat
     1861 tttatccaaa tctccttcca tttctgctgt gaaatggata tcgacgattt gagggaagaa
     1921 ttcacagatt aatgaattga caatttctcc tagttcagtc ggctcaaatc ttttttgtgt
     1981 caattttaca tagtagcgtc tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg
     2041 ccctaccccg ttttcttcta gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg
     2101 ttgagtaaaa tgttgttttg gttcaatatc aacagattgg actacatcgc cttcttcaag
     2161 ttctggaaga atattttctt tctcttcttt gccgtcatct ctaccttcca catacacttg
     2221 catgaatcct ttgaatttga tttttgaacc gttcgcaatg aagatgacac cattttgttc
     2281 taatgtcact ttcattgtat ctaaaatagc tggtgtcatc tgactagcca caaaacgtga
     2341 ccagatcaat gtataaagtt tcaattgatc tttatctaaa tattgtttga gttcatctgg
     2401 tgtacgaagc acactcgttg gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt
     2461 tttgatcttt cggtgatcat gtctagaaaa ttcttttcca tacgtatctt caataaatgc
     2521 tgcggcctct gcttttgctg tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat
     2581 caagccgact gttccttgtt tacccaaagt gattccttca tataattgct gtgctaccat
     2641 catggttttt cttgttcgaa agtttaactt acgggcagct tcttgttgca ggctacttgt
     2701 agtgaaagga ttcgcagggt ttcttttgcg ctctttcttt tctacttttt taacttcgaa
     2761 gtctgttcca tcaattctag cagtgacttc ttttacactt tgtgcatctg gtaatttctt
     2821 tttcttaccg tcgattcccc agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt
     2881 accgtcgatg ctccaatatt cttctggaac aaattctcgg atctcttttt cacggtcaat
     2941 aataattttt aaagcgacag attggacacg tcctgcactt aaccctttct tgaccttacg
     3001 ccagagaata ggactgatcg aataaccaac gattctgtct aaggtacgac gagcttgctg
     3061 tgcatctact aaatctacat cgatcgttct tggttcctta aaagctgctt tgactgcgtc
     3121 ttttgtgatt tcattgaaga ccacccgatt tttttctttc agatccaacc caagtaggta
     3181 cgctaaatgc caagcaatcg cttctccttc tctatccggg tcacttgcca agtaaacttt
     3241 ttgagctttt tttgctgcgg ctttcaggct tttgatgaca tcgccttttc cgcgtataga
     3301 aatataatgg ggttcataat tgttttcaaa atcgataccc attttacttt tcggtaaatc
     3361 tcttatatgg ccaacactgg ccattacttt atagtttcgt ccaagatatt tctcaattgt
     3421 cttggctttt gcaggtgatt ctacaatcac taaatattta tacgccatta ctgaatggac
     3481 tcctttccat tgtcgtgttc ctactattaa aagaggattc atacaaatcg tagctaatca
     3541 tatccattca gaaaacgttt gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa
     3601 attctgccaa gatatcttca cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat
     3661 gacatccggt agaatgttct gttaaaatat ttcctggaac agaaaaaact gttcttccaa
     3721 gatccaatgc ttgctgtgct gttatcagag agccgctttt tttcttggct tcaaagacac
     3781 atgttccttt agacaaagct gcgataatcc gatttctcat tggaaaacaa tgctttttcg
     3841 ggccggattg aggaggatat tcactcaaaa gaagatgatc atttgcaatc acctcttgca
     3901 agtcacgatt ttcagcagga tagacttgct ctatccctgt tccaatgact gcgattgtcc
     3961 gtccaccatg agagattgct gcttggtgac cgtatgtatc tatccctttc gcgcagccac
     4021 tgacgatcac atatccagct tctatcactg gttttagtaa ataataaact gtttttttgg
     4081 ctaaagcaga agtgtgtctt ccaccaacaa cgcttaacat gttacaagaa agtaaagata
     4141 gatcaccatt ataaaacagt acaattggcg gataggtcaa gtgaagcagc tgagggggat
     4201 atttgggatc aaagcaagtg ataaacgact gtttcgattg gattttgccc cagttagcgt
     4261 gaatttcctg ccaacttttg cgaaacagct cccgatgttt ggttatttta cctatcttaa
     4321 tgatgtcttc aaatccgatt tctttataag gatactgcat catccagtta gcaagtgccc
     4381 attttccttg actactgatt ccttttgtat aagcaagttt caataaattt tcttctattt
     4441 gatacatcat aaaaccgcct ttcgtctctc tttctaataa gatacgtaaa agcggctgtt
     4501 ttttattgta aatatttttt tacaggtgca aaacttttac gatggattgg cgtaattcct
     4561 tgtcgttcaa gtccttctaa gtgttccttt gttccataac ctgcattatg cgagaaacca
     4621 tatccaggat aaagcacgtc atattctttc atcaattggt ctcgatatac tttagcaatg
     4681 atacttgcag cagcaatcga cacagatcgt gcatcccctt tgattatttt ttcctgctga
     4741 ataggcaaat ccaaggtcat cgcatcgatc aacaaatagc ttggtacaat ggacaatttt
     4801 tctactgctt ggatcatcgc taatttactt gcttcataaa tattcacatc atcgattgtc
     4861 tgctgatcaa cgatcccgat cccgattgcc agggcttttt cttgaacttg ttgataaaga
     4921 agttctcgct ttttctctga taattgtttg gagtcattca gccctaatat gatctcattt
     4981 ttcggcaaga taactgcagc tgccacgaca ggtccagcta atggtcctct tcctacttca
     5041 tcaatgccgg caatccattg gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt
     5101 tcttcatatt tttccttaat taatgcttcc tttttcaatc gtcgttcaaa agaagccagt
     5161 gcttgctgca cgcctttgcg tggatcattt cttaatgatt ctagtgtagg atcatctatt
     5221 ctctgtatgc ttttcaatcg ttctttgata ctttggatgg attcagtcat cacttttttg
     5281 ctccatttct tcgcaacgat ccagtgtgta tcgtccaagt tttccttgac gaatatcatg
     5341 cacgactaat tcgctgccac gatcatagtc ttctttatac ccacgttttg ctgtaatatc
     5401 catcagtaat tccggtgcca atttttcttc ttgctcgatt gataaaccat aacgatcgct
     5461 gattcttcct gaataatatc gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa
     5521 atggacaagc tggtctttga tcgcgcctgt cagcgctagt tttttgccga tttcttcatc
     5581 ttcaaatttg ggccataaaa tccctggtgt gtctaacaat tccaactcat tacctaaacg
     5641 aagccactgc tgaccttttg ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc
     5701 tactagtcga ttcatcaacg tagatttccc aacatttgga atacctaaga ccattgcccg
     5761 aatagcgcga ggcttgatcc cccgagcagc atctcttgcc cgtttttctt tcaatgcttc
     5821 tttagccgca ggtactagac ctttaattcc tttactttct tgtgccgtga tagctaatgc
     5881 aagatggcct tgtttacgaa aatattcttg ccacagcttt gtctgttgtg gatctgccag
     5941 atccgcttta ttcaataaaa caaggcgagg tttttgctga atgatctgat ctagcattgg
     6001 attacgagaa gataaaggta atcgtgcgtc taccaattca aatacgatgt ccacatattt
     6061 cattttttca gaaacttctc gtcgggcttt tgccatatgt cccggaaacc attggatggt
     6121 cattgttctc tccattcctt tcataccgga atattccccg gctttacttg tttttttctt
     6181 tttcaatata aattcacttt tttattataa agaaattcca tctattagtt aagtgaaagt
     6241 gaaccagtcc tcattctatc acatcttcac ttttttgatg atgcaaattt ttattttggt
     6301 ttctatatat gaatctaaat ttttgacagc gtttcctaaa taagagatga tagacgaaca
     6361 aaacagaaag gagacgaaac aaatgaatag tatggttttt gttaattttc ctgttgctga
     6421 tgtcaatcgt tccgttgctt tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc
     6481 tactgaagaa gctggttcaa tggtatggg
//
LOCUS       DARBDN010000120         6287 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000120 DARBDN010000000
VERSION     DARBDN010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.123"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..177
                     /locus_tag="SCH06_002517"
     CDS             <1..177
                     /locus_tag="SCH06_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079045.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="SCH06_002518"
     CDS             190..690
                     /locus_tag="SCH06_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEG1079046.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="SCH06_002519"
     CDS             787..2634
                     /locus_tag="SCH06_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HEG1079047.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="SCH06_002520"
     CDS             2637..3533
                     /locus_tag="SCH06_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1079048.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="SCH06_002521"
     CDS             3583..3972
                     /locus_tag="SCH06_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEG1079049.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6287
                     /locus_tag="SCH06_002522"
     CDS             3959..>6287
                     /locus_tag="SCH06_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1079050.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1348 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacg
//
LOCUS       DARBDN010000121         6147 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000121 DARBDN010000000
VERSION     DARBDN010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.124"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            102..2543
                     /locus_tag="SCH06_002523"
     CDS             102..2543
                     /locus_tag="SCH06_002523"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEG1079051.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2873..3577)
                     /locus_tag="SCH06_002524"
     CDS             complement(2873..3577)
                     /locus_tag="SCH06_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079052.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(3764..4009)
                     /locus_tag="SCH06_002525"
     CDS             complement(3764..4009)
                     /locus_tag="SCH06_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079053.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(4026..4877)
                     /locus_tag="SCH06_002526"
     CDS             complement(4026..4877)
                     /locus_tag="SCH06_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEG1079054.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            5043..6047
                     /locus_tag="SCH06_002527"
     CDS             5043..6047
                     /locus_tag="SCH06_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEG1079055.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         1970 a         1064 c         1301 g         1812 t
ORIGIN      
        1 tttaaggatt gttaaaattt aatcttagaa aaaaataact ggaacaagag ctatttgttt
       61 ttacagcaaa gaatggtata tttttgtagg aggtggctta cttgaaagaa gtcgttatga
      121 tagatgctgc aagaacgccg ataggaaagt atcgcggaag tttaagtcca tttactgcag
      181 ttgaattagg cacacttgtg actaaaggat tattagataa aacaaaactg aaaaaagata
      241 aaatcgatca agtaatattt ggaaatgtcc tgcaagctgg taatggtcaa aatgttgcca
      301 gacagattgc tttgaacagc ggtctccctg tagatgtccc agcaatgacg atcaatgaag
      361 tttgcggatc tggtatgaaa gcagtgatct tagcacgcca gctgatccaa ttaggtgaag
      421 cagaacttgt gatagccggc ggaacagaga gtatgtctca agcacctatg ctgaaacagt
      481 atcagtcaga aacaaatgaa tatggtgaac caatttccag tatggtcaac gacggattga
      541 ctgacgcatt ttcaaatgca catatgggat taaccgcaga gaatgttgca acacaatttt
      601 ctgtgagcag agaagagcag gatcgctatg ccttgtcgtc ccagttgaaa gcagcacatg
      661 ctgtcgaagc cggtgtattt tctgaggaga tcatcccagt caagatttct gatgaagacg
      721 tgttatctga ggatgaagca gttcgtggaa atagtacatt ggaaaaactg ggcacgttac
      781 gtacagtatt ctcagaagaa ggaactgtaa cagcaggaaa tgcttccccg ttgaatgacg
      841 gtgcctctgt ggtgatcctt gcatccaaag aatacgcaga aaataataat ctgccttatt
      901 tagcaaccat caaagaagta gcggaggtcg gtattgaccc aagtatcatg ggaatcgctc
      961 caatcaaagc cattcaaaaa ttgacagata gatcaggaat gaatttatca acaatcgatc
     1021 tttttgagat caatgaagca tttgcagctt cttctatcgt agttagccaa gaactgcagt
     1081 tagatgaaga aaaggtcaat atatatggag gagcaatcgc attaggccat ccaattggtg
     1141 caagcggtgc acgtatcttg actacattag cttacggatt gcttcgtgaa cagaagagat
     1201 acggtattgc ttcattatgt attggtggag gtttaggctt ggcagtcttg ttagaagcga
     1261 atatggagca aacacataag gatgtgcaaa aaaaaaagtt ttatcagctt acgccatctg
     1321 aacggcgcag tcaattaata gaaaaaaatg tattgacaca agaaactgcg ttgatttttc
     1381 aggaacaaac actttctgaa gagctctccg atcacatgat cgaaaaccaa gtgagtgaag
     1441 tggaaatccc aatggggatc gcgcagaatt ttcaaatcaa tggcaagaaa aaatggattc
     1501 cgatggcaac agaggaacca tctgtcattg cagctgcaag taatggtgca aaaatctgtg
     1561 gaaatatctg cgcagaaaca cctcagcggc tgatgcgagg gcaaatcgtt ctatcaggaa
     1621 aatcggagta tcaagcagtg atcaatgcag ttaatcatcg aaaagaagag ctgattcttt
     1681 gtgcaaatga aagttatcct tcaatcgtga aacgcggggg cggtgttcaa gatatctcta
     1741 ctcgggaatt catggggagt ttccatgcat acttatctat tgatttttta gtggatgtaa
     1801 aagatgcaat gggcgctaac atgatcaact cgattcttga gagtgtggca aacaagttac
     1861 gggagtggtt ccctgaagaa gagattctat tcagtatttt aagtaatttt gctacagaat
     1921 cattggcttc tgcctgttgt gaaatcccat tcgaacgctt agggagaaac aaagaaatcg
     1981 gtgaacaaat tgccaaaaaa atccaacagg caggggaata tgcgaagctt gacccttacc
     2041 gtgcagcaac gcacaacaaa gggatcatga atggtataga agctgtagtg gcagctacag
     2101 gaaatgatac acgtgcggtt agcgcttcga tccacgccta cgcggcaaga aatggattat
     2161 accaaggatt aacagactgg cagatcaaag gggataaact agttggaaaa ctaacggtgc
     2221 ctttggctgt tgccacagta ggcggagctt ccaatatcct gccaaaagca aaagcatctt
     2281 tagctatgtt agatattgat tcagccaagg aactagcaca agtaattgct gcagtagggt
     2341 tagctcaaaa cctggctgct ttgcgtgcat tagttacaga aggaatccaa aaaggccaca
     2401 tgggacttca agctcgttca ttagcgatct caattggggc tattggtgag gaaatcgagc
     2461 aagttgcgaa aaaattacgt gaagcagaaa agatgaacca gcagacagct atacaaatat
     2521 tggaaaaaat ccgggaaaaa taaaaaagca atatctttag aagaataaag caagatttac
     2581 agttatttta tttactgcag atcttgcttt tttctctatc agaaaatatg tttattatta
     2641 gaatttttta tagttaaggt taggcatctt aagaaatcag gcaactccaa gatatcttca
     2701 ggtagaagag aagtcgccta acattgtagg atcataggtg atttgttgga caggtcaagc
     2761 tgatatttga gcctgatgtt agaaggaatt tctttttact tgctgtagaa attattatat
     2821 gactaaaaag gctgggattt taaatcccag ccttttatga caaatagaat ttttatcgat
     2881 cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat caaagtcaat ttgactttgt
     2941 atttccgttc gagtgctttt tcgataacga actcattttc agtagtcata gaaatagttg
     3001 ctaatttacg aggttcatca gcattttttt cattaataac tacttcatgt tcattttgtt
     3061 ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa atcagcaaaa cttaaagcgg
     3121 cattcgtatc agttgagcgt gtattttcag ttgtgtccgc ttttggtttt tccgtttttt
     3181 cttctggcac actgactgtt tcttctgtaa ctggtgtcgc aacagcttgc gcagttggtt
     3241 catcgttttt caatcgttga tcattccagt aagacacgat ttcaataaga agattgtcac
     3301 ggaatcgttc gaaaatcccg ttttctcctg aacgaattct ctttaataca gtattgaagt
     3361 tgtcatcgat tggcacgttg atccgtgtat cttcatttgt tttcccagct aatccgatcg
     3421 ttaagatttg acggtttttg ggatcaagca tgacttgtaa cggcaaacca taacgtcgca
     3481 agctctcttc ttctagagaa cggaataatt gtcctcttac accatccaat gaaggacgga
     3541 attgatttaa taatttttgt ttctgttttt tcttcatatg ttctctcctt cgctcatacc
     3601 ctttcgatta taagaaaaaa acagccaaat gaaaaggagt aatgcaaaaa aacttgcgta
     3661 tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt ttttgaaaga aaaataaaaa
     3721 atggaacgga ttatgtatat atacataatc cgttccattc tttctatttt ttcggtatca
     3781 aggcaaaaac aggtagttca ggtgaataaa tgacttcatg ttcgtgccag ggtttgacca
     3841 ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat ttgatcatgt gtccagtttc
     3901 ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa gacaaaatcg gaatgaaaag
     3961 tctgggtaac ttcttccgag agagaattca agcgttcgat tggatccata aaatcacctt
     4021 tcgacttaaa attgggtagt atctgggtct tttgctttgc cgactacacc atctaactga
     4081 tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa ataattcagt attttctttg
     4141 attctgcttg gtgtcactga cttaggaaga ggaaggaatt cgtgttgcag cgaccaacgc
     4201 aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga tttgtttcat ttcaggcaca
     4261 tcgaagattt taccagtgcc taatggacta tatgcttcga ggatcatatc atgttttttt
     4321 gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa ggaaaacttg attgaccatc
     4381 ggcataattt ttgctgtttt tgctagtgta tctagatggt ggggtaagaa attgctcaca
     4441 ccgattgctt tgattttacc tgcttcatac agttcttcaa atgctcgcca tgtatctgca
     4501 tttgcttgtt cccaattatc acgaaaagca acagggtttg gccagtggat caaaaacaga
     4561 tctaaataat ctgtttggag cttcttcaat gattcttcaa aagaagacat cacaagttca
     4621 tagctgtggt ttgcattcca taattttgtt gtcaagaata tctcttctct aggaattcca
     4681 ctttccttaa tcgcttggcc gacgctttct tcattcttgt atccttgggc agtatcgata
     4741 tggcgataac ctgcagccag cgcttcttta acagaggaaa cagcgacatc cccatcaggt
     4801 gtttgccatg tgccgaatcc tactaccggg atttcgtaac catttgatag acgataagtg
     4861 cttgttaatg aattcatact ttcagctcct tttttattcg ttcaactata agtgtagcgc
     4921 atttttcgaa aaaaagaatc cattttgttt ctactcttga aatttttgtt taaaagaaaa
     4981 tgattttgat tctggtattt ttgatttttt ttccgtaaac taagacagaa gggaatgaga
     5041 aaatggatat ctatttaaaa aaagcaattc tgcatattat tgacagagaa actggttctc
     5101 cagtcttttc acaaaaagag ctggatctga caaaagaata tattcgtgat tttcttcaaa
     5161 agaagatcca aaaaatctct tctgctcaaa caaaaactgg acaactagca gaagaaagca
     5221 tgatcgttga atcacttaaa atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg
     5281 ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc acctagtgca gatgtatttg
     5341 ttgtcttgta tgaattagat acagtgatgt acttatcttt attgaaagtc aattatcgtg
     5401 aggcttacac tcactttgtt gaagcagacg aagcagggat cgacaaccgc ttgattttga
     5461 atcgagcaat tctaggggcg aaaacacaaa aagcagatga agcattcgct gtgaatttga
     5521 ctgattggac ctacgaatta attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt
     5581 atttttctgg aagagtgatc gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag
     5641 tgatccaaaa agtagccaag catcttggaa aaaaatttga gacagaagaa tttgatatca
     5701 tggctgattt gaaagaagct gtctatgata cgatagaaga aaaaggtcgg ttggatcatg
     5761 agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc aaaaatggct tttaaagaag
     5821 aagtacaaga gcaaggattt gtcccagaag cacctcctgt aaaagaagta caagaaattt
     5881 ctgagaaaaa atttggaaaa caaaaattca agctatcaaa cgggatcgaa ctgatcgtac
     5941 cagtagatgt atatcgcaac ccagatttga ttgaatttgt gaataatccg gatggtacga
     6001 tatccgtgat gatcaaaaat gtggatgaag tattgaatcg tttataaaaa tgactagaat
     6061 attaggtgtt caagtaccag tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa
     6121 agacgaatat aacaaaaaaa gagcgtg
//
LOCUS       DARBDN010000122         6049 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000122 DARBDN010000000
VERSION     DARBDN010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.125"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            689..1600
                     /locus_tag="SCH06_002528"
     CDS             689..1600
                     /locus_tag="SCH06_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-relaxation family protein"
                     /protein_id="HEG1079056.1"
                     /translation="MKYLLHGYFIDYSTRNSSTLAILCLLHELRVVTRKQLYKLLNFD
                     RSISKQGVTNALVRLYEKQLIDRKKYGTEMYYYLTKEGHQSIGGYYTLPKVPEYNLNH
                     HLQINNYLIKGMALAKDHPHLKRIISERRTVYETKDLNPKTKGRKFFVPDFIFRFRDK
                     ENHEINWSFEIELTLKTRRRYREAIFPKYIRELRTRPESHLIYVTPSGAIQEELHAFK
                     RIFFKRETEKDASQQELFERLHIFSALEFEEGLKALLENDPAVNWRTVEREKIYPNGA
                     VQSRLNLFEESTENEEKPKVKFTPEVL"
     gene            2087..2353
                     /locus_tag="SCH06_002529"
     CDS             2087..2353
                     /locus_tag="SCH06_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079057.1"
                     /translation="MTTKNEQLKEQARKELQERGLIIEGSFEGDFETYIGCYARPINK
                     PTALDPMNEQEVKEQEKHAVNGFPQDFTEWYEWEINNGKLENFL"
     gene            2425..2766
                     /locus_tag="SCH06_002530"
     CDS             2425..2766
                     /locus_tag="SCH06_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079058.1"
                     /translation="MAKNTPYQVGDIFYSSWGYEQTNVTFWQIVKLTEKTAWFQPIQK
                     KTVEHYSSMSGKVVPMKDKFIEYPLAKTKDSIVKKRIDPETYPDMLCGYRSWDTFHRY
                     KNQAVYESSYY"
     gene            2821..3240
                     /gene="ssb"
                     /locus_tag="SCH06_002531"
     CDS             2821..3240
                     /gene="ssb"
                     /locus_tag="SCH06_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEG1079059.1"
                     /translation="MMNSVNLVGRLTKEVDLKYTPKGNATGTFILAVNRNYTNANGER
                     EADYIRCVIWRKAAETLAKYTGKGSLIGINGRLQTRSYQNQQGQTMYVTEVLVTDFYL
                     LESKEINEQRSKSMANNQNNSSIPGNEIQISDSYLPF"
     gene            3317..3613
                     /locus_tag="SCH06_002532"
     CDS             3317..3613
                     /locus_tag="SCH06_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079060.1"
                     /translation="MKIIDSYDQRTMQYLGSFDYTDENIINYVASLPPYQSVRLVDFA
                     SDELVLTTMGNFLDYVGDKKWLEKILSKLIAKQTGEEPINAIQLFNRYEQENND"
     gene            3628..4059
                     /locus_tag="SCH06_002533"
     CDS             3628..4059
                     /locus_tag="SCH06_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEG1079061.1"
                     /translation="MKRLKRSIFIVLALIDFVGTGCEAIDVQKAPLSEIKQAITKQDE
                     EQPLNTQVEIVNQNKPSFSEEDFSLENGTRQFFSDLDRLNRVGVASALLHKSRMPTEE
                     RDRLYIKPTGWKQKKMKNGDYLYNRCHLIGYQRATSFPISM"
     gene            4241..4546
                     /locus_tag="SCH06_002534"
     CDS             4241..4546
                     /locus_tag="SCH06_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079062.1"
                     /translation="MKLDMPGRYKLLRVRLFLIKLTNLRMYGSITDLYSKDIRLRMQR
                     TLSKSKNVGHEIRDGRLAVYLSRVGKTCLIDSDESGNATKRFTEEIEQLAELNIRYF"
     gene            4950..5438
                     /locus_tag="SCH06_002535"
     CDS             4950..5438
                     /locus_tag="SCH06_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEG1079063.1"
                     /translation="MKKTIFVLAIFICFGLLLVGYLLFNSNEMRTISTNDLLKKSELK
                     DKKKESLAFIMFTQEECEYCIAINPIIDSVNKETLNKIKKYDISVDFQSKQKCKIKFV
                     PTIVAYSKNKEVGRIDNELDNLYRKKQDGSIVIDKKKTKTLLIDWMKKMDKQGEYLYG
                     ED"
     gene            5425..>6049
                     /locus_tag="SCH06_002536"
     CDS             5425..>6049
                     /locus_tag="SCH06_002536"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1079064.1"
                     /translation="MEKIKQTFPLINKYWNKKKIFIFFITFLLSSLFSLIFPYLFSNV
                     IDLYLENELSQNIVRIVTILIFQLFLVLIKEVYGYIKTIYAFEVDLSMKIDFLKVLQK
                     KNLFFSQTKHSGEIQFRMFSDISTIVNTIFIFSVELPVIGVLVLVAVFIISKVNLIFL
                     IFSLIMMGAMVLQYNLFQLPLKKTIENTKSVNQSITGELNAHFDQLEI"
BASE COUNT         2231 a          854 c         1223 g         1741 t
ORIGIN      
        1 taaggattat ttgagggtta tttagagatt atttaaaggt tatatgtaat aagtgggggg
       61 agggctgtcg gcgcttggta tgaaaggcat tctccgactt ccaggttttt gaccattttc
      121 tctcaacgtg gaaaaaccgc cacttatgag agaaaatggt caaaaaccta agcgggaagt
      181 ctccgaataa cataccaagc gccgacagcc aacagataaa gaatacacta ctaaaaatag
      241 tagtagcata aaatttaaaa gggaaaaaat caacccctac cccagtcttg gggtctcaaa
      301 actaactccc ccctaacccc ctctttcagc ctcttttgaa agagggggag aatcaacccc
      361 acggccaacg ccccagtgtt cttggggctg tccagaacag aaacttgcga gagagtgggg
      421 gtaaaacaag tgtagaggaa acttgaagac ttgttcgaac agaaacttgc gagagagccg
      481 gagtaaaaca agtgtagagg aaacttgaag acttgttcga acagaaactt gcgagagagt
      541 tggagtaaaa caagtgtaga ggaaacttga agacttgttc gaacacaaac ttacaagaga
      601 ggggagtaaa gcagttgcag aggaatcagg aagatttgtt cgaacagaaa cttgcaagaa
      661 agcattatta aattgaaggt gatgaaatat gaagtattta ttgcatggct attttattga
      721 ttattctact cgcaatagta gtactttagc gattctatgt ttgcttcatg aattgagagt
      781 ggttactaga aaacagctat acaaactatt gaattttgac agatcaatta gtaaacaagg
      841 agtaacgaat gctttagtga gattatatga aaaacagtta atcgatcgaa aaaaatatgg
      901 aacagaaatg tattattatt tgacgaaaga gggacatcaa agcataggtg ggtattatac
      961 gttgccgaaa gttcctgaat ataatttgaa tcaccattta caaattaaca attatttgat
     1021 taaaggaatg gcattggcaa aagaccaccc acatttaaaa cggattattt cagaaagacg
     1081 taccgtctat gaaacgaagg atttaaatcc taagacaaaa ggaagaaaat tttttgtgcc
     1141 agattttatt tttcgttttc gagacaaaga aaatcatgag atcaattggt cctttgaaat
     1201 tgagctaacg ttgaaaacac gtcgtcgcta ccgtgaagcg atttttccga aatatattcg
     1261 tgagttgcga acacgtcctg aatcacattt aatttatgtg acacctagtg gcgcaattca
     1321 agaagaactt catgcgttta agcgtatttt tttcaagcgc gaaactgaaa aagatgcgag
     1381 tcaacaagaa ttgtttgagc ggttgcatat tttttcagct ttagagtttg aagagggatt
     1441 aaaagcatta ttagagaatg atccagcagt caattggcgg acagtagaac gagaaaaaat
     1501 ttatccgaat ggcgctgttc aaagtcgttt gaatttattt gaagaatcaa ctgaaaatga
     1561 ggaaaaacca aaagtgaagt ttacgcctga agtattgtaa aagagggtgt tcgcttcgct
     1621 ctttttttgt gccagtttgc tggcaccgtt cagacgcaag cgtctgaacc ggctcgtttt
     1681 taggaaggac taacttgttt gatttatccg ttgtcaaaga agtggacgtt cgagagtccc
     1741 taatcgtata gcagtcattc ggcgagtata acctaaaaca taacctgcca attgccaagg
     1801 gtaaaatgca cgctgcgcgc ccttggcaat cgtcagaaca tgttttcgag ccggttatgc
     1861 cgaacgaccg ctatacgaaa agggcctcta aacagaagtc cactttgatc cttgacaact
     1921 gaaacccaaa atcaaacaag caggccttcg tctaaaaacg agccgaatga agaccttggg
     1981 ggttgcaccc ccaaaccccc gtgcccccga cacactaccg aaaaggtggg ggtgggtggc
     2041 gaaaaaatca aataaaacat tctattcaag aaaggaagaa acaaccatga caactaaaaa
     2101 cgagcaactg aaagaacagg caagaaaaga gttgcaagaa agaggtttga ttattgaggg
     2161 gagctttgaa ggagattttg aaacctatat tggttgttat gcaagaccga taaacaaacc
     2221 tacagcctta gacccaatga acgaacaaga agtaaaagaa caagaaaaac atgcagtgaa
     2281 tggttttccg caagatttca ctgaatggta tgagtgggaa attaacaacg ggaagcttga
     2341 aaacttctta taaaagtcag atgacgtgca aagagaatga ttctctttgt acggtaaaaa
     2401 tataaagaaa gaaggaaaaa gaaaatggca aaaaacacac cttatcaagt aggagacatt
     2461 ttttatagta gttggggcta cgaacaaacg aacgtgactt tttggcaaat tgtgaagtta
     2521 acagaaaaaa cagcatggtt tcagcctatt caaaagaaaa cggtcgagca ttattcgtcc
     2581 atgagtggaa aagttgttcc aatgaaagac aagtttatag agtatccttt agcaaaaact
     2641 aaagacagta ttgtaaaaaa acgaattgat ccagaaacct atcctgatat gttatgtggt
     2701 tatcgtagtt gggacacgtt tcatagatat aaaaatcaag ctgtttatga aagtagttat
     2761 tattaagggg atagtttccc ctttcaaaaa taataaatag aagaatggag agaaaaaatc
     2821 atgatgaatt cagtgaattt agtaggacgg ttaacaaaag aagtggattt aaaatacaca
     2881 ccaaaaggca atgcgacagg cacatttatt ttagctgtta atcgaaatta tacgaatgca
     2941 aacggcgagc gtgaagcaga ttatatccgc tgtgtcattt ggcggaaagc tgcggaaact
     3001 ttagcaaaat atactggaaa aggaagtttg attggcatta atggacgtct tcaaacgagg
     3061 agctatcaga atcagcaagg acagaccatg tatgttacgg aagttctagt gacagatttc
     3121 tatttgttag agagtaaaga aatcaatgag caacggtcaa aatcaatggc gaataatcaa
     3181 aataattctt caattccagg aaatgagatt caaatttcag atagttattt gcccttttaa
     3241 gtgaaaaata attttgttct atacctgatt tcttcaggta tagaacaaaa aataaataga
     3301 gatgaggcga ttttttatga aaatcattga cagttacgat caacgaacca tgcaatattt
     3361 gggctcgttt gattatacag atgaaaatat tattaattat gttgcaagtt tacctcctta
     3421 tcaaagcgtt cgcttggtag attttgcaag tgatgaattg gtattaacaa cgatgggcaa
     3481 ctttttagat tatgtcggag acaaaaaatg gttggaaaaa attttgtcta aattgattgc
     3541 gaaacaaaca ggagaagaac ccataaatgc gattcaattg ttcaatcgat atgaacaaga
     3601 aaacaatgat taaagaggag agaaaaaatg aaaagattaa aacgaagtat ttttattgtg
     3661 ctagcattga ttgattttgt tgggacaggt tgtgaagcaa ttgacgttca aaaagctccc
     3721 ttatcggaaa taaaacaagc aataacaaaa caagatgaag aacaaccgct aaatacacaa
     3781 gtagaaatag tgaatcaaaa taaaccgagt ttttctgaag aagatttttc gttagaaaat
     3841 ggaaccaggc aatttttttc agatttggat cgtttaaatc gggtaggtgt agcaagtgca
     3901 cttttgcata aaagcaggat gccaacagaa gaacgagacc gattatacat taagccaact
     3961 ggctggaaac aaaagaaaat gaagaatggc gattatcttt ataatcgttg tcatttgatt
     4021 ggctatcaac gtgcgacaag tttccccata agtatgtaat acgaaacggg aggattaatc
     4081 ttaagattaa tcacaactaa cctatttgac agttggaatg aaagctatca tgtctgctga
     4141 atcaactggt ctgatactcc tacatgcaat aaagtctact aggaagttat tgtatgaagc
     4201 taggtaaagg cggcagaaca atttctaagt gtggaatcat atgaagttgg atatgccggg
     4261 acgctataaa ttactcaggg tgagactgtt tttaattaaa ctgacgaact tgcgaatgta
     4321 cgggtctata accgacttat attcgaaaga tataagattg cgaatgcaaa gaacattatc
     4381 gaaaagtaag aatgttggtc atgaaattcg agatggaaga ctagcggtgt atctgtcaag
     4441 agttggtaaa acatgtttga ttgattcaga tgagagtggg aatgcgacaa aacgttttac
     4501 agaagaaata gagcaactag cagaactgaa tatacgatat ttttaaatac tttagcggag
     4561 aataaaaaaa tcctctacag aaaactacgg agggcaacat gtgctattgt ttcaacaata
     4621 catttttaat ttttaccata acaaaaaagt acttgaaaaa aaacagaaat atgttaaatt
     4681 aaaaatgaaa aaatggaagc ggttacttat tcttttgaat ctaagataaa aattcaaaag
     4741 aataacataa cccaaatatg attatacttg agattctaaa tatttatcga aaaggaattt
     4801 gttttaagga aaaatgattc tatggacggt tattgattta tatttaccaa atggctaata
     4861 aaatagtatt tcttatattg tatagttttt gtttttatgt gaaaacatga gcaatagaat
     4921 tgtactagta ggataaggat ggatggaaaa tgaaaaaaac tatttttgtt ttagcgattt
     4981 ttatatgttt tgggctactt ttggtaggct acttgttgtt taattctaat gaaatgagaa
     5041 ctatttctac gaatgacttg ttaaaaaaaa gtgaattaaa ggataaaaaa aaagaatctc
     5101 ttgcctttat aatgtttact caagaagagt gtgagtattg tatagcaata aatccaatca
     5161 tagatagtgt aaataaggaa actttgaata agataaagaa atatgatata tctgtagatt
     5221 ttcaatctaa acaaaagtgt aaaattaagt ttgttccgac tattgttgca tatagtaaga
     5281 ataaagaagt ggggagaatt gacaatgaat tagataattt gtatcgaaaa aagcaagatg
     5341 gttcaattgt aatagacaag aaaaaaacaa agacattgct tatagattgg atgaaaaaaa
     5401 tggataaaca aggagaatat ttgtatggag aagattaaac agacatttcc gttaattaat
     5461 aaatattgga ataagaaaaa aatttttata ttttttatta cgtttctgct gtcatcttta
     5521 ttttctctaa ttttcccgta tctatttagt aatgttattg atttatattt agagaatgag
     5581 ttatcacaga atattgtgcg aatagtaacg attcttatat ttcagttatt tttagtctta
     5641 attaaagaag tgtatggata tataaaaact atttatgcat ttgaagttga tttatcaatg
     5701 aaaattgatt ttcttaaggt tttacaaaaa aaaaatcttt ttttttcgca aacgaagcat
     5761 tcaggagaaa ttcaatttag gatgttttcg gatatttcta ctatcgtaaa tactatcttt
     5821 attttttctg ttgaattacc tgtgataggc gttttagttc ttgtagcggt atttattata
     5881 agtaaagtga atcttatttt tctgattttt tcactaataa tgatgggagc tatggtgtta
     5941 cagtataatt tatttcaatt accgcttaag aaaacaatcg agaatacaaa aagtgttaat
     6001 caaagtatta caggagaatt gaatgcacat tttgatcaat tagaaatta
//
LOCUS       DARBDN010000123         5877 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000123 DARBDN010000000
VERSION     DARBDN010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.126"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..290)
                     /locus_tag="SCH06_002537"
     CDS             complement(<1..290)
                     /locus_tag="SCH06_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEG1079065.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTET"
     gene            complement(283..624)
                     /locus_tag="SCH06_002538"
     CDS             complement(283..624)
                     /locus_tag="SCH06_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079066.1"
                     /translation="MNKELSTLDQYLTDSEWGKSNIKETNNRKIRRNLLTNEELSCDQ
                     DDLGNFVSIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYNRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(798..1523)
                     /locus_tag="SCH06_002539"
     CDS             complement(798..1523)
                     /locus_tag="SCH06_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HEG1079067.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDGSNFGQMFVEGNEPDSYGRSRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
     gene            1576..2052
                     /locus_tag="SCH06_002540"
     CDS             1576..2052
                     /locus_tag="SCH06_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079068.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNTDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            complement(2058..2240)
                     /locus_tag="SCH06_002541"
     CDS             complement(2058..2240)
                     /locus_tag="SCH06_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079069.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEHRAKKASREGLTKI"
     gene            complement(2240..2539)
                     /locus_tag="SCH06_002542"
     CDS             complement(2240..2539)
                     /locus_tag="SCH06_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079070.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
     gene            complement(2644..2847)
                     /locus_tag="SCH06_002543"
     CDS             complement(2644..2847)
                     /locus_tag="SCH06_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079071.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(2862..3608)
                     /locus_tag="SCH06_002544"
     CDS             complement(2862..3608)
                     /locus_tag="SCH06_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEG1079072.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            3686..3994
                     /locus_tag="SCH06_002545"
     CDS             3686..3994
                     /locus_tag="SCH06_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079073.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            complement(3965..4222)
                     /locus_tag="SCH06_002546"
     CDS             complement(3965..4222)
                     /locus_tag="SCH06_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HEG1079074.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(4520..4660)
                     /locus_tag="SCH06_002547"
     CDS             complement(4520..4660)
                     /locus_tag="SCH06_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079075.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            4960..5280
                     /locus_tag="SCH06_002548"
     CDS             4960..5280
                     /locus_tag="SCH06_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1079076.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            5298..5729
                     /locus_tag="SCH06_002549"
     CDS             5298..5729
                     /locus_tag="SCH06_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEG1079077.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
BASE COUNT         1707 a         1081 c          939 g         2150 t
ORIGIN      
        1 tctgtttccg tatgtccttt aaccgttact gagacagata cataagtccc tgtttcatcc
       61 ataagaaaag gtttatattc ctcaacaaga aagtcttgat gagttccaga aacaaccctg
      121 tagtgtttat actcattaat agttaccgtt gcctgtggat cattcttttt cataatctcc
      181 cacgcgtgag cccaagataa ataatcaaaa tttccttttt tcttgagaat tttatttaac
      241 ttacgactaa aaagtttttc aaagttcgtt gtccctttga tttcactcat caaattctgc
      301 ctccatttca gcaatgtatt tcttacctga tccgtaataa gagatatcaa tcaagttatc
      361 tctgttgtac tcttctagcg catcaatcaa gccatcttcg atgacataga tgtattcagg
      421 tttatttgaa tgttttgata gatggataag gtaaacatga tcccaaatac tcacaaaatt
      481 tcccaagtca tcttgatcac atgatagttc ttcgttcgtc aaaagatttc gtctgatttt
      541 tcgattattt gtttccttga tattcgactt gccccattca gaatcagtca aatattgatc
      601 taaagtggaa agttctttat tcatatgcta aaattctcct tagatatgtt ttgtgactct
      661 atgcttgccg gctgagtcac ttttttattt gttgccatgc tttttgcttt tcgatatgtt
      721 gttggcttag gatgtttggt ttattgtgtc tccaccagcg attagcaatt accgtcccta
      781 ttcttagcgc ttcagctcta ttcattttca tcaccgaaaa gtctttgttg tctgttcagt
      841 tgatcgattt ccatgcggat cgcagtttct ggtaaccaca tttcaataaa tgaaacagca
      901 tcatcgaatc tcttacgagg taactcgcca tatcttggga ttgaaaaggt acgtttaaat
      961 tcagaccaaa attttgagaa tacttttttg ctgatttctt cataagctcg gctttctttt
     1021 ccccctagaa cttccataac tttcatattt cctttttgct taatttcaaa ctcttgttgt
     1081 ccgctaattc gcatagtatc tttaagcatg gaaacatctt ttttaacatc tttcatttct
     1141 tctaattgat agatcatcat gtcttcaatt gtttgaggaa cagtattctt ccgaataaca
     1201 tcttccattt cgttgaaagc ttcaataaat tttagtttga aatttattgc tttacttcca
     1261 gtgaatccca tagctagcaa ggaaaatccg tctctattca tgaaataaac tctccgactt
     1321 cttccgtatg agtctggctc gttcccttcc acaaacatct gtccaaaatt ggacccatct
     1381 tcaacattgg ccgaattttc gaccgatctt tttattgatt caattgcttc tagtacatgc
     1441 ttatgtttct ttttgaaact ttctgccact tgtaagctcg tagttacagc ttctttattt
     1501 ttcaaaatta ctaattcttg cattatttct tctctccttt ttggtataat tttcgttaga
     1561 aagtgaggtg attctatgag gaaaaagctc aattacattc ttactgcgac tttaaccata
     1621 tatataattc tgtttattac cttatctttc ctgtcttcaa ttaaaaaaat tccttttatt
     1681 acattgaata aaaatagtat tttgaaggag ttcaataaca ctgactacat cgcatttcta
     1741 aaactttttt cagtctgtgt gctaatatca tgtgtaatta tttttattgt tgctaaaaca
     1801 tgttggacaa tgttaaataa aaaccaacgc gatgttgaaa atattgctat atttttaatt
     1861 aagattactt cctcaatatc aattatcatt ccgatgactg taactttttc aaaagaacag
     1921 tttaatgtag cggctactta tctttcattt atagcgctat tttcttttgt tcttcctaaa
     1981 agaaataaga gcaactttga caacaaggag ctggatgaag tacgcaatag cagcccaaag
     2041 gaacaaaaat aaaaaaatca tattttagtc agtccctccc gactggcttt tttcgctctg
     2101 tgctcagctt catcaagccc cataaaaatc caaaccatgt aaacgattgt ccctatcaac
     2161 gcttgtctgc ttccccagag gcctaaagcg tagatgatta gcggtgcgct gaatactagt
     2221 gctctgttga atttgcccat taacttgcct ccttcaaaac atctgaaggc gataaacttt
     2281 ttacacgata tttgtttgcg tctttccact ttaaaaacca aataaaagta tggtaatgaa
     2341 taaatgtggt tgagtgacct ggacgaagta ttccttctgc aaattcagga attgtttcca
     2401 tttccttgca gtattcaact aaagtagttt ttgacatgcc gtggaacttc tccaagatta
     2461 aactttgtcg gtaccagtcg tctggtttta ctgccttctc agcagcttct atcagctctg
     2521 aaagtgttgg ttttttcact tattatccct cctaaaaatt atcgttccat actcgatgtt
     2581 taacatttct tgaagctctg attttgtaag aatgatttta tcttccaacg actttacctc
     2641 cctctacaat tcgtacatag tgataatcga atctataatt ctgtttgctt ctgcagaagt
     2701 ctttttaccg tttaaaatta aagataagta gcttttgcta attccaaatc tttcagcaag
     2761 catggtgtaa gttaagaact ttgaactttc gacatattct ttgatttttt ctctatctcg
     2821 ttgagtgatt tctgcaatgt cagtcatact aaaactcctt tctaaccaat ttcctctaaa
     2881 tccatttgag ggtaatagcc ctctgcgatt aataagttgt aaataaacac tcgccctttc
     2941 tgtgtccatt tggtattcat tacaacttta gtgccgccat cggctttcgg tatctcactt
     3001 gtgtgcgatt ttgtgtatcc ttggttcata tgttttcggt aaagtatcca ttgtccgcta
     3061 actttatgct gaacacctaa ctcgtttagc aatttgttta gagcaattgc cgacattccg
     3121 taatcagctg caatttgaga agtagctacc gtatctgtcg atgaaagaat cgtatctaag
     3181 tagctaatct ttggttcgta ctcggcaatt tgttgttcga gtaattggtt cttttcttct
     3241 aaatccgctg ctaaacgcaa tgcttgtgca aaactttgag gtacgtttga atagctacct
     3301 gtttttctaa ttgttggaag gacttcactc gttacccaac gtttaaattt tttggcagag
     3361 ggaagttttg attttaagat taaactgtaa aggcctgact cgttaatcaa aacaactgct
     3421 gttccattga cggtgaacga atcgttctgc gtcttatcct ccaagtccac atgatctcga
     3481 atagcttttt gcggattcga atatcctaga acgtctgcta catcttttcc tacaaaatat
     3541 ggttcatcat ttactaaaat agttcgaact tcgttttgct cgaaattaaa aatttgtggt
     3601 gtattcatat ttctcattcc tttctttggt ataatttcct tatcagtgtg acaggctgaa
     3661 ataattgtta aggaggtgaa aatttatgaa accagaattt gtaattacta tgcttgatgg
     3721 agaaaaaatc aaaatatttg ccgatacttt ggtcgttgga tacgatgatg cgtcaaatat
     3781 cgaagaaaaa gatggaatgt tctattcttc tcaaatttac gtgaatacct tgcaaggtga
     3841 tattggggta tctactcttg caacatcaag accgcttgta ggtcttatcg gctttttgtc
     3901 aaaagcaaca ttcttttctc tcggcgatga tatagattcg gatgaaactg tcatctataa
     3961 aacatcagct gttaaaagta tcggtttcaa atagtaattc ttgctcgttg atagcggaag
     4021 ccaacttttc ttccaacaca tcggcgagct ttctttttgt tggattcatt tcaaagttga
     4081 tagtcttgag aagcattttt gcatccttaa ctttttgtcc ttgcaattcc ttgatgattt
     4141 tatcggcttg gctatcaatt ccatgtgtta gatcatctat cattttttgt accttgattg
     4201 tttggctcat ttccttgttc attgtttagc ctcctttaat aaatgatttt ttgtattttt
     4261 taatttccat aaattcctca aattgctctt tggtattatt accacgacca tacatattgt
     4321 gaaattcttt atggcaactg acacaaagtg taacgccgtt tgaaatcgct gcggatttag
     4381 ttgttgcatg gctaaatcac gaatcacaag tatctactaa aggcgaatca atttcgccaa
     4441 aagaaattgt tcaagcttat ttagatattc attatgctgt tatctatggt cagcttccag
     4501 aagaccgtaa aaacgatgac taaacgtgag ctaaaatctc tgctatggct gcaaccatgg
     4561 cagagtcttc tttatctacc gcgtgttcca tcgccacttt tgcttgtttc agtatgtcta
     4621 atttcaaatc ttcgattttt gccgagactg ttttttccat attcttctct cctttctttt
     4681 atattcgtaa acaaatttaa caacttttta aaaaactgcg ttgactttat tagattaata
     4741 atctatacta aatgcatagt taaataagac atataaactt tgatttaaaa agctttcttg
     4801 gcggttggca tttattaatc aatagtattt tttgttgtct ttttagttgt taaacttgtt
     4861 tacaaaacat agtatagatt aataatgtat ataagtcaac tatttttaca ttatttatct
     4921 aaactttttt tgtaagcatt cagaaaggtt gatttatcaa tgaatactta cgaaataata
     4981 aaggagttag caaaagaaaa aggattatcc attagacagc tcgaaatgaa tttcgggtat
     5041 tcgaatggat atttaggaag ttggaaaaga caaactccta attctattga gttagctcgg
     5101 ttagctgatt actttggagt ctctgtagac taccttctag gtagagaaga aagagaaacc
     5161 cctaaacatg tggatttatc agaaaacgat actgtttttt cttttgatgg aaaagaaata
     5221 tctaaggaga caatgcgtaa agcgattgca attgctaaag ctttagagga aaatgaatag
     5281 ttggagtgat gggttgtatg tatttgaaat tgaaagaaat gttgagcgaa tacaatttga
     5341 aagtagttta catggaaatg aaagagcctg gcttctatta tccgaagcct agaatcattt
     5401 ttttgaatga aaatctatat ggcgaaactg cagaagcctt tcatttatct catgaacttg
     5461 cgcatttcac cgcttctcat tttgaatatt cagttttgta cgatacttct acaacttttc
     5521 actcaaaatt tgaaacagaa gcagataaaa tagctattct aattttatta aatatctata
     5581 ttgagaacga actgactgat gaatctcagt ttaatctcga aaaatttatg gagtattatt
     5641 ctattcagaa taagctcaga tacacttgtt atgctgtctg ccaatgctat tttaagaaaa
     5701 aatattctta cgcaaggcaa tatgtatgaa tacatcaaga attattaaaa aaaccgattt
     5761 cagcaaaaca ttaaaaaagc ccgtgctggc acacggactc atacctcatt tctgagatcg
     5821 caaatatatt ataacaagaa gtgaggaata tttaaatggc aaaaaaagtt atgggtc
//
LOCUS       DARBDN010000124         5859 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000124 DARBDN010000000
VERSION     DARBDN010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.127"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..395
                     /locus_tag="SCH06_002550"
     CDS             <1..395
                     /locus_tag="SCH06_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079078.1"
                     /translation="ISLKDESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQE
                     YYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKI
                     GVINFKNKYQIKGIKLSHETIKKLRIGG"
     gene            398..1228
                     /locus_tag="SCH06_002551"
     CDS             398..1228
                     /locus_tag="SCH06_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEG1079079.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKMQRNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            1244..2095
                     /locus_tag="SCH06_002552"
     CDS             1244..2095
                     /locus_tag="SCH06_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEG1079080.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            2092..2451
                     /locus_tag="SCH06_002553"
     CDS             2092..2451
                     /locus_tag="SCH06_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HEG1079081.1"
                     /translation="MNKYRNKKTVHRGIKSDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCSQYRV
                     PLILAKKYRNTFKEERF"
     gene            2466..2627
                     /locus_tag="SCH06_002554"
                     /pseudo
     CDS             2466..2627
                     /locus_tag="SCH06_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            2624..2929
                     /locus_tag="SCH06_002555"
     CDS             2624..2929
                     /locus_tag="SCH06_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079082.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWAEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            2929..3240
                     /locus_tag="SCH06_002556"
     CDS             2929..3240
                     /locus_tag="SCH06_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEG1079083.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGANIQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     E"
     gene            3237..3410
                     /locus_tag="SCH06_002557"
     CDS             3237..3410
                     /locus_tag="SCH06_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079084.1"
                     /translation="MMMPKEIYSDALRGARNQLKMAKRAYEIRPTIENERRVKAIRRR
                     CSIYGELQKEDSK"
     gene            3407..3823
                     /locus_tag="SCH06_002558"
     CDS             3407..3823
                     /locus_tag="SCH06_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HEG1079085.1"
                     /translation="MIPRFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIWENSELLEEQ"
     gene            3823..4491
                     /locus_tag="SCH06_002559"
     CDS             3823..4491
                     /locus_tag="SCH06_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEG1079086.1"
                     /translation="MNKQELIDELAKYVKRYENVMDEHGQGRYGAYEVSLKLVKRLNE
                     SKITDEQAWNKVAEAYPESAQSLRNTLDNAVFGKTGEPQKHVMPKFVAEWIEYAKKKG
                     DSLAISFKPWNLYGVEYSKADRWIGDNQETFARAWLDGYEVEKEPLYYVPLPYEVWDE
                     EAAELKTEYLYLHYEITSDETRIFPTKEPRKGFVAKLDELTIKSADENYWPFAVPVEE
                     VVEG"
     gene            4488..4865
                     /locus_tag="SCH06_002560"
     CDS             4488..4865
                     /locus_tag="SCH06_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079087.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQVKMVQISHLQLEL
                     EDLRQIEDPYQLNDNQQIVLEWLKLTASTGKPMQVVFWMMNNAAWGHLDELRDPLMEL
                     TDKQQFEVLTAFAQWGLEQEEKE"
     gene            4862..5161
                     /locus_tag="SCH06_002561"
     CDS             4862..5161
                     /locus_tag="SCH06_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079088.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKLLAKSKDNLAVVRLVDMEVINNEI"
     gene            5151..5309
                     /locus_tag="SCH06_002562"
     CDS             5151..5309
                     /locus_tag="SCH06_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079089.1"
                     /translation="MKFKIFEEDTRYKLEKKLNEFAKNNEIQHISLTASKSGYTTYYA
                     AVVSYVIQ"
     gene            5403..5819
                     /locus_tag="SCH06_002563"
     CDS             5403..5819
                     /locus_tag="SCH06_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEG1079090.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
BASE COUNT         2175 a          886 c         1361 g         1437 t
ORIGIN      
        1 aaataagcct caaagatgaa tcgaatacga ctgtgagtga tgctaatgtc ttagcaaata
       61 tcatcttaga tttcatcttt gaacatcata ttcctttcaa agaaggctat gagattttac
      121 cagcgaatca agaatattac ttctacaaat gcattacaaa aagagtttgt tgcatctgtg
      181 gcaaaacagg agctgacatc gatcactttg acaaagcgct aggaagacga aagcgaaaag
      241 aagttgatca ttcagagtac acatttgcag cactctgcag aatccatcac acggagaagc
      301 acaaaatagg tgtgatcaat tttaaaaata aatatcaaat caaaggaatc aagttaagtc
      361 atgaaacgat taaaaagtta aggataggag gataaatttg gctgagataa gttggatcaa
      421 acttaaaact actatgtttg acgatgaaaa aatacggtta atccaagctg ttcctgagtc
      481 ggatgccatc atcgttatat ggattcgatt actagtttta gcaggaaaga ctaacgacga
      541 tggtctgata tatatccaga ggaacatgcc ttataccgaa gaaatgcttg ctacattgtt
      601 tggcaaaaac gtaaatacgg ttcgcttagc gctaactaca ttggcaaatt tcaacatgat
      661 tgatctaagc agtgatggac taattgccat cagtaattgg gaaaaacatc aaaatatcga
      721 gggtatggat aaagtaaggc taaaaaatgc tgaaagaaac cgtaaataca gggaaagaaa
      781 gagacaggaa cgtctcaaat tggaaaatga cgttagcgtg acgtcacgtg acggtacaga
      841 taaagatata gaagaagata aagatataga taaagaagaa aagaaaggta agtattctga
      901 cgaacactta cgccttgcta aaaaaatgca aaggaattta actgaagatt ttccaaaaga
      961 aatgaacaaa gtagatatcg aaaaatgggc agacacaatc aggttgatgg aagaaagaga
     1021 taaagcatct atagaagcga ttgagtatgt gatcaattgg ctacctacaa atgaattttg
     1081 gtttggaaat attagaagtg ctaagaaatt gagagaaaaa tttgagaagc tcaaattcga
     1141 aatcaaagca gacaagaaga atcataaaaa gcaaagtcaa aaactacagt acagcaatcc
     1201 tagtgaatat gacgacttgc caatttaaaa ggagatgcat cacatggaaa gcctagcaaa
     1261 tgctatggag aagctaataa gaagagtatt agtgcaaagc ggaaaatgtc cagaatgtag
     1321 cgaacctttg tatagttggc gagctaaaaa taaggatggt tcagaacgtt gtaaaccaac
     1381 atgtatgagt tgtggttata aagcgttacg tgtgaaagag gatatacaga ccgaacggat
     1441 atataacgac agcttaaaag cacgagcatt gagttttttt caaaatggtt cggtattaac
     1501 agataaaact ttgtttaaat gcaaaatgga gaattatcac gtagtggacc aagaaacgaa
     1561 aattgcttta gaaagagcta aaagctatgt aaatgatgtc ctactgaacc atcctgcaca
     1621 tttcattcta tcagggaaat caggaagcgg aaaaagccac ttatcaatgg cgacagcttg
     1681 ggaaatactt gagcgctcaa attatgacaa gaaaatactt tttataagct atcaagagtt
     1741 attagagcaa ataaagtttt cttataacaa tgctgaactg agaaaagaaa ttgaaggatc
     1801 gcttatagcc gatatcaaaa caactgattt ggtggttttt gacgatattg gagctgaatt
     1861 aggtagcggg gtatcaaata gtaggcaatt tacaaacaac acgttaaaca cgctcttaga
     1921 agccagacag aacaaggcaa cgatcatcac aacaaactta tctggtcctg aactaagaga
     1981 agcctacggt gaaagaattg tttctaggat atttaagaat tcagaaggtt atgcgctgaa
     2041 attccaacaa acagcagaca agcgcataaa accagtgaaa ggtagtatcg catgaataaa
     2101 taccgtaata aaaaaactgt tcatcgaggt atcaagtctg attctatcgc agaagcagag
     2161 tattacgatc tagccttgtg gcaagctgaa gcgaacggct ggaaagtaaa acttcaggaa
     2221 agatttgagc tgatgccgaa atttgaacta gacggaaaga agtatcgcaa gatcgagtat
     2281 attcccgact tcacatttta taaaaacggc aaactagtca aagtcgtaga tgttaaaggg
     2341 atgcagacaa aagatttcaa aatcaaagcg aaactcttct gcagtcaata tcgagtacca
     2401 ctgatcttag cgaagaaata tcggaatacg ttcaaggaag aacggtttta acgaggtgat
     2461 ccatcatgac aacagaagaa gtgattcaaa tgcgtattcg aagccttcag cgtgagattg
     2521 acgatctgta acggacaaag gcagtgatgg tcaatgaaac ggcgaggaag gcaatcgatt
     2581 tgcacataga aaatttaaga aggaaaatcc atcgattgga ggaatgagcg tggataagaa
     2641 agcagcaatg aaacgaatca tcgaactgac acattctgag aattggcaag aagacaaaga
     2701 aatagttgca gaagtccaaa agctcggtaa atcaatgtgg gctgaaaagc ctaaacggaa
     2761 aacgccgaga aaaattgcaa tctggcatgg tgatcgaatt ctagtaacag gtactgctga
     2821 acagttatct gaaattactg gattaagcaa aaacattatc tgggatagag ctaggagctt
     2881 atggattgat tcaaaaggac gacagtttag gtatgtggag gagaaataat gaacgaacta
     2941 atcacaaaag tagagcagtg ggctaaagac aagggactgg atcaagcgga tccaaaagca
     3001 caatttttga aagtagctga ggaattcgga gaaattgcat cggcaatggc aagaagtaat
     3061 gatgagctat ttaaagatag cgtaggagac gttatcgtca cgctgattat tctttccatg
     3121 caaaaagggg caaacataca agagtgttta gaaatggcgt ataacgaaat caaaggacgc
     3181 acaggaaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggagga cagcgaatga
     3241 tgatgccaaa agaaatctat tcagatgcat taagaggtgc tagaaatcaa ttgaaaatgg
     3301 caaaaagagc atacgaaatt cggcccacaa tcgaaaatga acgcagagta aaagcaattc
     3361 gccgtagatg ttcaatttac ggcgagttac agaaggagga cagcaaatga taccgagatt
     3421 tcgagcttgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc attttactaa
     3481 aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga aatcatatca
     3541 cgtgcgaaac atcgagctca tgcaatcaac agggctgaaa gataagaatg gcattgagat
     3601 tttcgagtgg gatattgtat cagtcagcgt gcgaaatgga ttcgattatt tagataataa
     3661 agtttgtgtt gtcaaaaatt caataggaca ttcgggatta gtgtgtgcca ctgttgatga
     3721 agatttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt atgaagtcat
     3781 cggaaatatt tgggagaata gcgagttatt ggaggaacag tgatgaataa acaggaattg
     3841 attgatgaat tagctaaata tgtaaagcgt tatgagaacg ttatggatga gcatggccaa
     3901 ggaaggtacg gcgcttatga agtatcttta aagttggtga aaagactaaa tgaatcaaaa
     3961 attacggacg aacaagcttg gaataaggta gctgaggctt atcctgaatc ggcacaaagc
     4021 ttgagaaaca ctttagataa tgctgtattt ggtaagactg gtgaaccgca gaagcacgtt
     4081 atgccgaagt ttgtggcgga gtggatagaa tacgctaaaa agaaaggtga tagtctagct
     4141 atttcattca agccgtggaa cctctatggt gttgagtata gcaaggctga tagatggatt
     4201 ggagataatc aagaaacgtt tgctcgtgct tggctagacg gctacgaggt cgagaaagag
     4261 ccgttgtatt atgtcccgct accatatgaa gtttgggatg aagaggcagc ggagcttaaa
     4321 acagagtatt tgtatctaca ttatgagatc acaagtgatg aaactagaat atttcctaca
     4381 aaagaaccta gaaaaggttt tgtcgcaaaa ttagatgaac ttacgattaa atcagcagat
     4441 gaaaactact ggccgtttgc tgtaccagtg gaagaggtgg tagaaggatg aaaaaattgc
     4501 accaactcat atctgagaaa gaaagcgaac tccaaaattt agaagatagt ttgggattgg
     4561 ggtttccaat tgttgagcaa gttaaaatgg ttcaaatcag tcatctacaa cttgaattgg
     4621 aagatttaag acaaatagaa gatccgtatc aactcaacga taaccagcaa atcgtgttgg
     4681 agtggttgaa actaactgcg tcaacaggaa agccaatgca agttgtattt tggatgatga
     4741 ataatgcagc atgggggcat ttagacgaat tgagggatcc tttgatggaa ttaactgaca
     4801 aacagcaatt cgaagtccta acagcattcg ctcaatgggg attagaacag gaggaaaaag
     4861 aatgaaacta aaagacggat tttacgctag tagccacggt atcggcggtt taatgctaga
     4921 catgccgaca aagaacccta aaacacgtaa gaagccaaaa gtcaaagtcg gtgacatggt
     4981 tcgctgtgaa gcagaaggat tcatctatcc atttcgtgga tatgtagaac acgtctataa
     5041 tcactcagcg atcattcgca ttgaaaacac gatggaatgc gacaagttat tagcgaaaag
     5101 caaagataat ttagcagtgg tgagattggt ggatatggag gttataaaca atgaaattta
     5161 aaatctttga agaggacact cgctataaat tagaaaaaaa attaaatgaa tttgcaaaga
     5221 ataatgaaat tcagcatata tctttaacgg cttctaagtc aggttataca acttactatg
     5281 cagctgttgt gagctacgta attcaataaa aggaactcgg caaataaaaa agccggatca
     5341 ctccgactga tgtaataaat ccgacaagtt tattatatca cataaaggag cggtttgact
     5401 tgatgcaatt gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc
     5461 tgaagaactt tcggcgcttg gagcggatgg caggtcgctc tttgatagat attaagtcgc
     5521 cgattattac ggatatgccg aaggcaccga agcacggcaa taaggcagaa gacgcgatca
     5581 ttcagatgat ggatatagaa gcggagagag acgcgatttt agcggctttg atggcgctta
     5641 gtctgattag ccgtcagata ctctactaca gcttctgtga cgtaaacaag cactctaatt
     5701 atgaaatagg gcaattgata cgaggatacg gagagaagaa tgtagagaag ctgaaatcca
     5761 tcgcattgat cgaatttgct gaagcataca aaaaaggcgt gttagttcag tatcgttaat
     5821 tttgtagggt ttttgtaggg atagtgtagg gtttttgag
//
LOCUS       DARBDN010000125         5809 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000125 DARBDN010000000
VERSION     DARBDN010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.128"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            450..1604
                     /locus_tag="SCH06_002564"
     CDS             450..1604
                     /locus_tag="SCH06_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HEG1079091.1"
                     /translation="MIILKPKNKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1598..2020
                     /locus_tag="SCH06_002565"
     CDS             1598..2020
                     /locus_tag="SCH06_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079092.1"
                     /translation="MVNKPIVLVMGLVLVLFLTSCSKKQEIQKTELIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3143..4075
                     /locus_tag="SCH06_002566"
     CDS             3143..4075
                     /locus_tag="SCH06_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEG1079093.1"
                     /translation="MANEIVKYKPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFDQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEADNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRTKLFNIEHNGELTQEEKWRAKDRILDLPLGTHEAN
                     FKKQQQTEKEEVEKQTLSNELKQDLLGNLQNLFD"
     gene            4092..4607
                     /locus_tag="SCH06_002567"
     CDS             4092..4607
                     /locus_tag="SCH06_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEG1079094.1"
                     /translation="MADKTIKDLAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINE
                     IGQKAIKSMFFTENENSNQQPVGEKSKTENHKNANQVSELELFFFLEKQLNQKDIQLQ
                     EKDEQLKQMQKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQ
                     NKEKKWWQFWQ"
     gene            4903..5184
                     /locus_tag="SCH06_002568"
     CDS             4903..5184
                     /locus_tag="SCH06_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079095.1"
                     /translation="MDILVRNINPKIITRVDKRCQELTTKTGEKWSRNKYLKVLIESD
                     FDRQLMNYKKEQFDLLLEKFIDIQTKNTETLNDYVHTNNQLIETLIGGI"
     gene            5186..5602
                     /locus_tag="SCH06_002569"
     CDS             5186..5602
                     /locus_tag="SCH06_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079096.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EKQLNPSQRNQPKNRQKETSQTFTSKNFDPTNFLKR"
BASE COUNT         2228 a          961 c          930 g         1690 t
ORIGIN      
        1 aaaaaaaaag actgctcgaa agagcagtct caagcaaaaa ataaacgaac aaacgcaatt
       61 actcacgaac acaaacaaat acaataaaat acctaaataa tgaaaataag tgataaaaaa
      121 caagggtatt tatagtttaa caagcgctca taaaaataac aagtctttaa aaaatgacag
      181 ataaaaatgc acaaagaatc ggacacagat aaccgcgaaa aatcaagctt tagaaagttg
      241 tttttagcta gaccaatgaa aaatcacaaa gtccgcccct gtatccgttg gtagaggggc
      301 tacttggttt agtatacatt atgttaacta gctcgttaaa taacgattat gttcccaaaa
      361 caatatttta tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg
      421 tgtatatcac ttaattttaa cacaaaggcg tgattatttt gaaacccaaa aataaaattt
      481 atctaggtct cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct
      541 atgcttcaga aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta
      601 attttgcgaa aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca
      661 ctgaaactga tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata
      721 cggcaaatag ttctattttc tttccagtat tttcagacgc tgataatacg attaaatatg
      781 tttataccgt caaaaaaaat acaaatggag aatattcagg aagtatttca caatttttag
      841 caaaagaact tcaaaatcta gtagatagca atataacaga tacaacctta ttttttcaag
      901 ataatagcat ttattattcc gataatggcc aaattaaact actttggaaa tcacctttaa
      961 gtacagaaaa aaatggtgtc tcttccttta cagaaaaaaa tgatcttata tccgtaaata
     1021 taaaaaataa aattaaaaat ttctctaaaa aacaaaattt tcctgcggtt aaacgtgtaa
     1081 aaagtgtctc ctccggagat aactttatta tgattaattg gcgtatagca gaaacccaaa
     1141 caagttttcc gtggtgcgct gcttacgtag aagctgctat cttatgtaat aaaacagatg
     1201 tacgcgctac ttcagctaga gccattatgc attataccta tcctaattta aacaacagtc
     1261 aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat tactgtggtg
     1321 tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca caactaagaa
     1381 aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac agccgtcatg
     1441 cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat gtgtggaatc
     1501 cttggtataa ctacccaact gtaataagtg caaatgcagg gccagttaca attcctgtac
     1561 ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac ccattgtttt
     1621 agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac aagaaataca
     1681 aaagactgag ctgattcctt ttctaggaac ttggcaaact aaagatcact cagaacgtct
     1741 agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct tagtaaaaga
     1801 gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac aagttttcat
     1861 ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat tagattacac
     1921 ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg atgggacaga
     1981 agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg tttgatatta
     2041 caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt ggctagcatt
     2101 tgctagcctt ttttgtattg cggagcgtga gttttgaggg ggattcaagg gggagtttct
     2161 cccctttgac aagcggttat ttgcaccaaa tacgaaggta tttggctagc aaatatagag
     2221 cttgccaaac cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca
     2281 aacgatacgt cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat
     2341 ttggctagca atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt
     2401 cgagtgagcg aatccgaatt tgcaaatctg aagctttgca aatgagtgtg ccggcttccg
     2461 taaaagtcta ggtaacatta gtcgatatat acataaggct ctaatttgcg ttttaaggcg
     2521 ttttaaacgt tctggtatgt aatttatacc aaagcgactt taaaacgcct taaaacgaat
     2581 tttataggtc ttgtaggacg tttcagggtt gttagggctt gccctgaccg cctgtaaggc
     2641 gctttaaaaa caagataagg gattttatct agacttgtct taaaacgccg tagatgagcg
     2701 ctcagagctt cttaaaggac tccttacgaa ctgtttttaa gcaaaggagc ctttaggcga
     2761 ctgcgcagtt caatgtgaga gcgtagcgat cacaccttta aagcgaccgt agggagcaga
     2821 ttcccagttt aggaaatttc gcgaacctgt ttggagaaaa aaagtaggaa atttttaggc
     2881 gggaaatttt gcccccctct tttataatct cttttataac ctctttttaa acctctttac
     2941 cgtcggctgt atccttactc tcccaaggcc tgtagctttt ttagggcatg aaattatctg
     3001 tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata ggcatgaaat
     3061 tatctgtttt aggtattgtt ttaagacata atatacctta aaattatgtc aataaaatta
     3121 gttagactgg agtatcaaat aaatggcaaa tgaaatcgta aaatataaac cagaattaaa
     3181 taccattcct ttaaggaaat ttactccaat agaaatgaac ttgttttttt ctattgtttc
     3241 tagaatgcgt gataaaggta atcaaaaaat acgcttttat ttcgatcagc ttaaagattt
     3301 aagtgcttat aagcaaactg ctggagaagt ctttataaaa gatttaacaa gaacatacga
     3361 tcatttaatg gatttacgtt ttggaaaaaa aagcaatggt ggattaacca tagaacgatt
     3421 tacaatgttt actgattttg aaattcatgg agaagccgat aacccttatg tggatataaa
     3481 agttcacgaa aaagctttgc ctttacttaa caatttagaa agttgggtac gtttctcttt
     3541 aacagaattt cgagatttaa atagcagtta tgctaaaaca atgtttagat tactaaaaca
     3601 ataccgaaca caaggatggg ctgaattttc caaggaagat tttttagaac tattagatat
     3661 tcctaaaagc tatagacaaa caaatataaa tcagtttgta ctcaaaccca taaaagaaga
     3721 actcacacca ttatttaaag gattaacgat tcgtaaaaaa tatggtaaag gccgaggcaa
     3781 acctgttatt ggttatcgtt ttacttggaa agctgaaatt aatcatgctg acgatttttc
     3841 aaaagggaag caagaagatt tacgtacaaa attatttaat attgaacaca atggagaatt
     3901 aacgcaagaa gaaaaatggc gcgctaaaga tcgaatacta gatcttccgt taggtactca
     3961 tgaagctaat tttaaaaaac aacaacaaac tgaaaaagaa gaagtggaaa aacaaacact
     4021 ttcaaacgaa cttaaacaag atttattagg aaatttacaa aacttattcg attaaagtat
     4081 aaggagtatt tatggcagat aaaacgatca aagaccttgc tgaagaatta ggagttagta
     4141 agacagctat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt gcgaaaatcg
     4201 gaaacaagtt tgtgattaac gaaatcggtc aaaaagctat aaaatcaatg ttttttaccg
     4261 aaaacgaaaa ctcaaatcaa caaccagttg gcgaaaaatc gaaaaccgaa aaccataaaa
     4321 acgccaacca agtttccgaa ttagaactct tttttttcct agaaaaacaa ttaaatcaaa
     4381 aagatataca gctacaagaa aaagacgaac aattaaaaca aatgcaaaaa ttactcgacc
     4441 agcaacaaca actcacctta caagccaatc aacaaatcaa aaaacttcac gaacaactcc
     4501 agctaaccta tgcagaagaa tcttcagaaa aagaacccct ttctgttact gaagaaactc
     4561 aaaaaggaca aaacaaggag aaaaaatggt ggcaattctg gcaataaccc aacaattttt
     4621 attcataaaa attgttgggt tactttcttt ttttgctttt acaagcatag cgacatgatc
     4681 tcacgtcgct attttttaaa gagcataagg aaacgcggta tcactttctt acgaaaggtg
     4741 ctaggtaggc tgtgcctacc acgtttctaa gaaaaaaatt tgctatcact ttttcgccat
     4801 tgtggctagc ttatgtatag tatttcggta aaaaacagct atacaaatac tatatttgta
     4861 tgatatacat aaattataca cacataagaa aggacgtttt ctatggacat tttagttcga
     4921 aatatcaatc caaaaattat tacaagagta gataaacgtt gtcaggaact tacaaccaaa
     4981 acaggagaaa aatggagtcg aaataaatat ttaaaagtgc taatcgaaag tgattttgac
     5041 cgtcaactta tgaattacaa aaaagagcaa ttcgatttat tactcgaaaa atttatcgat
     5101 attcaaacaa aaaatactga aacattgaac gactatgttc atacaaacaa ccaactcatt
     5161 gaaacactta tcggaggaat ataacatgag aaaaacttct gttcaaaaac acgttaccct
     5221 ttatcccagt cacattgacg ttttagattc catcatcgaa aaaaatccag atatcaataa
     5281 ctactcggaa gccattcgct ttttatgtat gagttatgaa cctgatacca atacaacaac
     5341 taccagtaac caagccaaac taaatgcgat gggaaaagaa atttctatca tgaccgaaat
     5401 tatcgcagaa tttgctgatt tgtatttaaa agatacaggc gttcttatcg gtacaaactc
     5461 gaaagtatat caagaagtaa aagaaaaaat tgaaaaacag ctaaatccct cccaacgaaa
     5521 tcaaccaaag aatcgtcaaa aagaaacgag tcaaacattc acttctaaaa atttcgaccc
     5581 aaccaacttt ctaaaaagat aaaaaaataa accaggaaat ttttaatttc ctggtttatt
     5641 ttctagagag cggtcttcca ataagatttg caaatcgatc ccaatttgcg taaaaaaaaa
     5701 gctgctcgta cgagcagcta aacaagaaaa agtcagcttg ttttaagggt aaaataagtg
     5761 taacaaattt tgcgaatgca acgatctttt ttattatacg caaacaatc
//
LOCUS       DARBDN010000126         5791 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000126 DARBDN010000000
VERSION     DARBDN010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.129"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(99..1229)
                     /locus_tag="SCH06_002570"
     CDS             complement(99..1229)
                     /locus_tag="SCH06_002570"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEG1079097.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="SCH06_002571"
     CDS             complement(1877..3079)
                     /locus_tag="SCH06_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1079098.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="SCH06_002572"
     CDS             complement(3139..3342)
                     /locus_tag="SCH06_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEG1079099.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="SCH06_002573"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="SCH06_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="SCH06_002574"
     CDS             4879..5691
                     /locus_tag="SCH06_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079100.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1717 a         1189 c          922 g         1963 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta g
//
LOCUS       DARBDN010000127         5670 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000127 DARBDN010000000
VERSION     DARBDN010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.130"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            32..2185
                     /locus_tag="SCH06_002575"
     CDS             32..2185
                     /locus_tag="SCH06_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEG1079101.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            2154..3569
                     /locus_tag="SCH06_002576"
     CDS             2154..3569
                     /locus_tag="SCH06_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEG1079102.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            3602..4636
                     /gene="sppA"
                     /locus_tag="SCH06_002577"
     CDS             3602..4636
                     /gene="sppA"
                     /locus_tag="SCH06_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEG1079103.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            4638..5159
                     /locus_tag="SCH06_002578"
     CDS             4638..5159
                     /locus_tag="SCH06_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEG1079104.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            5156..5542
                     /locus_tag="SCH06_002579"
     CDS             5156..5542
                     /locus_tag="SCH06_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEG1079105.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
BASE COUNT         2034 a          769 c         1074 g         1793 t
ORIGIN      
        1 aaaatttttt agaaggagtt gtgttagata agtgataaaa tcatttcctt ttgtgcagca
       61 acaagatgaa aaagattgtg gtgttgcttg cctttcgatg attttaaaat attttaaaac
      121 tgatatcccg attcataaat tacgggacct atctgggact gatttagagg gtacttcagc
      181 atttggattg aaaaagacat ttgaaaaatt gtcttttgat tgtatggcta ttcaagcaga
      241 tagtgagatc tggaaagaaa gagatcttat cttaccatta attgcacata tattggttga
      301 taacagctat atgcactacg ttgtaattta taaaacgaag ggaaacgtac tatggattgc
      361 agatcccgct aatggaaaaa atagaaaaac gattgaagcg tttcaaaaag aatggacagg
      421 tattctttta ttacctatgc ctagagaaac ttatattcct attaaagaaa aagtagctgg
      481 attaagttct tttttgccta taatttggaa acaaaaagga ttagtattcc acatcgtttt
      541 agcatcgatt ttcattacgt tttttggcat aggaagctca tattattttc aaggtattct
      601 tgattttttc atccctaatc aagcacgttc aactttaaat ataatttcca ttggcttgat
      661 cgctgtctat ttatttcggg tattgtttga atatagtcgt agttatcttc ttattatttt
      721 aggacagcga atgagtatgg caattatgct tcagtatttc aaacatgtgt taactttacc
      781 aatgaatttt tttgctacga gaaaatcagg ggaaattatt tctcgttttc ttgatgccag
      841 taagattatt gatgctttag caagtgctac gttatcaata tttttagata ttggtatggt
      901 gttgcttgtt ggggttacgt tagctattca gaatagtacg ttgtttttaa tcactctatg
      961 ctctttgcct ttttatgtag ttgcaatatt cgctttcgtg aaaagctatg aaaaatcgaa
     1021 cagggaagaa atggcagccg gtgcagctgt aaattctagt atcatagaaa gtcttaaagg
     1081 aatagaaaca attaaagcat atagcggtga agagaaagta tataaccgta tagaccatga
     1141 atttgttaaa ttaatgaaaa aatcatttcg tacggttacg cttgataata ttcaacaagg
     1201 aattaaacat ttgattcaat taattagcag tgcattaatt ttatggctag gttcttattt
     1261 tgttatggat aatagaatta gtctaggtca acttatcaca tacaatgctt tactagtatt
     1321 tttgacagat cctttacaaa acattattaa tttacaagtg aaaatgcaaa cggctcaagt
     1381 tgcaaataat cgtttaaatg aaattttcgc gattgattca gaaaaatcga accagtcttt
     1441 tgaatatatg ctttctgaac aattatttca acaagatatc actgtaaaaa acgtttcatt
     1501 ctcgtatagc atgaaggccc caacgttgaa cgaaatttca tgtacaattc cttcgcacag
     1561 taaaacggct atagttggag ttagtggttc tggaaaatca actcttgcaa agttatttgt
     1621 tcgtttttat gaagcatcag aaggatcgat ccattatgga aacattaatc acttagacat
     1681 tccttttcag atattacgcg atcgagtgac atatttgcct caagagtcat ttttctttag
     1741 tggaacaatc attgagaatc ttatattcgg tttagatagc ccaccaagtt tcgaacaaat
     1801 aatagaagtt tgtgagatag tccaactaaa tgaatttatt aatcaacagc cattacgtta
     1861 cgagacattg ttggaagaag gtggaaataa tctttcagga gggcaacgac aacgattagc
     1921 cttagcacgg gctttattaa aaaatccgga catattaatt ttagatgaag caactagtgg
     1981 attagatacc ttgttagaac atgcaattat gaattatctc ctcaatttaa aagaaaaaac
     2041 gattattttt attgcgcatc atttaccaat agcaaaagca tgtgatcaaa ttttagttct
     2101 ccatgaaggg catttggtag aaaaaggaac gcacgatgaa cttcgttttg ccgatggtat
     2161 ctatcaaaaa ttatgggaaa tctaggagag ggaaacaatt tatgcagaat aataattggt
     2221 tcgaacattc tagtatctat actaaacaac atcatagctt ctaccgttgg gtgttatacc
     2281 ctgtaattct ttttttatgt attattggat tgtttttaac ctttgctaaa aaagaggttg
     2341 ttattcggac aacggctcaa ttgaaccccg aaaaaataga gaagttacaa gtgccattag
     2401 aagctaaaat aatggaaaac ttcctaaaag aaaatcaatt tgttcataag gacgatgtgt
     2461 tggttagatt ggattgttct ttaatagaga atgaaaaggc tcagatagaa caagaaaacc
     2521 aacgtattac tcaacaaata aagatggctc agctatttat tgaaagtata agtaaaggaa
     2581 aaaatttgtt ttcaacggat gacagttttg gctacagtaa tcaattaaag agcatgttgt
     2641 cagaaaaaga atcactccgc tacgctttga agcaaagtga attaaatgat caaaagcaat
     2701 tagaagtata cgaaaagaca aaaagacaac tagaaaaaca aattgagagt tcagatagta
     2761 aattacaaga atggcaacaa gtacaggtag cttggagtaa taatcaatca ttaaaagatt
     2821 tttcaaaaga aatgatggca aactatgaga attggcaaga acaactaaat aatgtttctg
     2881 atgatcaaaa aaatcaagtg aaactgacaa tttcagcaag cataaatgaa caaattgagc
     2941 aactaaaaaa agaagtagaa cagtatcagt cagaaaaagc taaattagtt aaaccaacta
     3001 cttctgagaa tgacagaatt agtcaaacgg aaaaaggaaa gcaagagcta gaacaagcaa
     3061 taacaactgt aaaacaaaca gttacagagc taaatgaaaa acaagagaag aaccagtcag
     3121 ttatcaaaag tttggacgat caactttcaa aaggaatact aaaagctcct gtatctggaa
     3181 cggttcattt aaatgaagaa acaaagggac aagcagaact agccaaagga acagtgcttg
     3241 cagaaattta tccgatccac gaaaaatcaa aaatgaaatt tacagcactt ttacctgcga
     3301 atgaaagtac ctatattaaa gaagggatga aggttcattt taaattggat caaaaaggtg
     3361 gggctccgat tacgatcgac ggaactttag atgaaatttc agaaaattct actgccactg
     3421 agaaaggtgt tttttatgca gtgaaaggaa cgttaaaaac aactcaatcg tttccgtttc
     3481 gttatggatt aactggagag ttgtctttaa ttgtaggaga aaaaacatat tggcaacaaa
     3541 ttgtcgatgt gtttctaaat aaaaaataat tatttttact aagaatatag gaggagttta
     3601 tatgaataaa agaagatgga ttgctgtggg agtagcgtgc ggattattgt tactatccat
     3661 tatcgtcgcg ctaattccag gaaaagataa agaggaagca tcaaatacaa ccctaacagg
     3721 aataaataag attttttacg gatctaacga aatcacagaa gaaacgttag aagaaggcgc
     3781 atcaaataaa aagattgtca aactatccgt caatggagtt attgcagata caggtgaaag
     3841 caatcttttt agtagggaac aatataacca tcagaatttt ttaacacagc taaagaaaat
     3901 tcaagaagac aaagcggtta agggagtgtt attagaagta aattcacctg ggggaggaat
     3961 atatgaaagt gctgagattg ctaaagaaat ggcaaaaatt aaaaagctag atattcctat
     4021 ctatactgca tttaaaaata cagcggcaag tggagggtac tacatttctg ctggttcaga
     4081 taaaatattt gctacggaag aaacaacaac tggatcaatt ggtgtcatta tttctggttt
     4141 aaattattct ggcttattag aaaaacttgg cgtaactgat gcgacgtata aaagtggtgc
     4201 attaaaagat atgatgtcac ctcaacacaa accttcagag gaagagaata aagttataca
     4261 ggaatttgtg atgagtgctt atgatcgttt tgtcaatgtt gtagcaaaag gaagaaatat
     4321 ggatactaat gcagtgaaag aacttgcgga tggaagaatt tatgatggta accaagcagt
     4381 agaaaatggg ttggtggatc aaattggtta ctctgaagat gcattagatt ccctaaaaaa
     4441 agagaagaaa ttaactgatg cgacggttat agaatataaa aatgacacaa ctggctttgc
     4501 ttcttcttgg ttaggtaata agattgctga atggcaaggg ctaaaggcaa ctacatcaga
     4561 tcgtgtaatt tcagtttttg aaaaacttgg attttctgat actccaaaac caatgtatta
     4621 ctatggaggg ctataaaatg aataagaaga gtggcattga aactttgcct aattatgtat
     4681 ttgcgggatt ttggttacga ttttttgctt ttcttattga tttaatttgt attagcatca
     4741 tcacccatgc tactataggt ctcttttaca aaatcatggg actggaatct gacaaatcca
     4801 ttattacttt ttatggtata gcgtcattag ctatttattt aacctatttt gtacttttga
     4861 ctaagctgaa ttcaggacaa acaattggga aaatgatttt tgggataaga gtagtgagct
     4921 ttgaggaaaa agagctaagt tggcaaacta tctttattcg tgagtgtata tgtaggttta
     4981 tattaaaaaa ttttgtattt caaattgggt atttggtggc tgctttcacg cccaagaaac
     5041 aacatattgg ggattatttt tctaacacgt cagtggttgt tattcgttca ttagaagcta
     5101 ttaactatgg tcaaaaaatt tctaattcta aaacacttaa tctggagaga attaaatgaa
     5161 taagagaaaa acagagttta ttttgatttt aattagtgga ataacaggga ttttatgtag
     5221 tcttttagca ttgatgggtg gtatgtttct atcttctatt gattcaacta ctttaaatac
     5281 tacagaacta accagtaagg atatagatat gttagtcaat ctaagcggga atgttgtttt
     5341 atttggagga attaccctag ttttttcgat aatgattttc ataataggtt ttttagtaag
     5401 aaaaaatcaa aaaacagtgg tctatggtat tagtttactc attttatcta ttattccatt
     5461 ttttctttta acattattgt gggtaattcc tggagtttta ggtattattg cgggattgat
     5521 gcttctaata agaaaatctt aattaggcaa tgtgtagaca acgtgaaacg attaatcaat
     5581 taaaagctaa atacgttttg agaaatgata acttgtagtc gatggaagac atgtagataa
     5641 aaaaactacg tgtcttttat ttattctaat
//
LOCUS       DARBDN010000128         5581 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000128 DARBDN010000000
VERSION     DARBDN010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.132"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(29..250)
                     /locus_tag="SCH06_002580"
     CDS             complement(29..250)
                     /locus_tag="SCH06_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079106.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            complement(247..537)
                     /locus_tag="SCH06_002581"
     CDS             complement(247..537)
                     /locus_tag="SCH06_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079107.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            complement(534..1718)
                     /locus_tag="SCH06_002582"
     CDS             complement(534..1718)
                     /locus_tag="SCH06_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEG1079108.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            complement(1900..3303)
                     /locus_tag="SCH06_002583"
     CDS             complement(1900..3303)
                     /locus_tag="SCH06_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEG1079109.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            complement(3325..4098)
                     /locus_tag="SCH06_002584"
     CDS             complement(3325..4098)
                     /locus_tag="SCH06_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079110.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            complement(4108..4485)
                     /locus_tag="SCH06_002585"
     CDS             complement(4108..4485)
                     /locus_tag="SCH06_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1079111.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            complement(4506..4820)
                     /locus_tag="SCH06_002586"
     CDS             complement(4506..4820)
                     /locus_tag="SCH06_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEG1079112.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            complement(5020..>5581)
                     /locus_tag="SCH06_002587"
     CDS             complement(5020..>5581)
                     /locus_tag="SCH06_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEG1079113.1"
                     /translation="LKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLYKFVTK
                     HIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGITLTTA
                     HKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNLFLFSE
                     VGYFTSKGDLLYPTQLLDKIEFDYNI"
BASE COUNT         1652 a         1100 c          940 g         1889 t
ORIGIN      
        1 cttcctattt tatcatgaaa aatatctgtt aagcaccaat gattcggtta aataagttta
       61 ataacacatc tttcacgcca gctgcattga acacaagtcc gacggcgatt agagcaataa
      121 tcaagaagcc aatgagtttt gaaaattctc gtttaaaacc taaaaacagt ccaatgacaa
      181 caatcgctaa caataccaat gactgtgcat tatccaagaa ccagttgtac aaattctgcc
      241 caaaattcat gtgattgtcc tcctttcctt aagatatttt tctcgataat agatatagct
      301 ttttacacgc cttaataatt gaaaaggggt taaatgctct ccatagacgg ttactcgatt
      361 ggtataatta ttataaaatc tcaccttgta aaaatcatag gtatagatgg tatcaccagc
      421 ttgccgtttt ccctcaataa tgagagacgt atatttccct gtattttgta tatacgcttg
      481 aaactcaatg ccacactgaa accctaactt ctttaattct tttgttaaaa ggctcatgta
      541 atcaaatcct ccatggctag atgttgttgt tcaattaatt tctcatgttt ttctgtcagt
      601 ttggcttcct gaatcatggt ggagataatg gttgtaccgt tgagaacatc taaaatgctt
      661 gcgattttta atgtaggggc gacttgatga tgtaaccagt tcaatgttcg ttcaaaagaa
      721 taaggctctg gctgtgtggt taggcgtaat gctccacgat ttttaccgat aaaccattcc
      781 caacgttcat tagttttcca atcactccga cgtttagtgt cgtctttatc tgcaaagcgg
      841 atatagcgat tgataatttc aaaggctgtt ttttccgcct gttgatgtgc caataaatct
      901 ttcatggctt gggtggctcg gtcatttttt aaccgaattt caaaccgatt ctttacttct
      961 gcgtcttcta agggaacatc atttttcacg tattgctcat aatctttctc atatatacag
     1021 aaatagactt cactttttaa tgagccaata taaagtgtgt ttcccatgta tggtttttca
     1081 tcacggtgaa ccaattcacc actgcgataa tttttaaagc ttcgaaagac ggaaatgcat
     1141 tcttcctgtt tacatttctt tgccaaatct ggaatattca aaatccctgt tttatcgttg
     1201 atagctaaat ccaagcgttt gaaaatacct ttatgttcca tgcaatcttg aaagaaatca
     1261 taccagctcc gatgttgagc caatagaaag ttttcaaatt gccgacagcc ttttcctttc
     1321 agttctaata aaacaccttt acttacatca tgagagacta ggacaacaat atcaccgaaa
     1381 cgatagtgtt cgggataaga ataatagcca aagtcttcgt gtagcatata atccatattc
     1441 aaacgtaaaa cctcaccgat aatttgagcc acatcattgg tagggaatcg aatccgtaca
     1501 tagtcgaata acatctccaa tgggttatcg ggattgaagc gttccaaagc gttcagtaaa
     1561 tcttctttca cctgttgagt agggactgcc ttgcctgttt caatatccga taggtaaggt
     1621 ctggtaatat gagaagcaac cgccagttta ttttgagaaa cgccataagc cagtcgcttt
     1681 tctttcaatt ccttaatcca aattttttcg ttttccattc gcaaacctcc aatctaaaaa
     1741 agatgtaaac tatgaccctt gagtttacac ctttcatatt ttccgcaatc ctttgtacca
     1801 tcaacattgg ttgatgagaa ttgcctgttt tcagttgtat ttgtgccccc ctgttagata
     1861 gagggggcta aaggattggc gtggctaacg ccacaccaat caaagcaagt ctgaacctgt
     1921 acctttcact tcgtgcggta caggctcaga ttgctttttt tgaatgactt ttcctatttc
     1981 tcctaagaaa tcgtaccttt ttggtacaag gggtgtataa aactcactaa tcacactttt
     2041 tcctgtatcc acgtaacctc ttcccttgat gggttttaag aaaaattgtt tttgtgtatc
     2101 gcttccgaac atcataccaa agcccatttc agacatacga cccaaagcca cacggaagtt
     2161 aaagttgtcc cgaatcccat cactaaaata ttttgcgtct ggacgttgac aggcaagaat
     2221 taaaaagaag cctgcttgtc gtcctaacat tacaatttgt ttgagtttat gaataacggt
     2281 ggtactttca cgacctagca tatccatcat tgccacatat tcatcaaaaa taagaaaatt
     2341 ggcagacaaa ccaagataag cataattttc tcctgtttta tagttagggt gttgtttcat
     2401 ggtttcactg cgatcaatca tatcttcgta aaattgattg atacatgcca acatatcttc
     2461 tttacggtaa tagacattat tcatgaccgc ccctaagtct gccaaatcag catttttagg
     2521 gtcaagaata taaagctttg catttgtatg caggagagat tcaatcaatg tgagaataaa
     2581 ataggatttt ccactaccag tgcccccagc aattaacatg tgagggagag aatcgaactc
     2641 ccaatagacc gattccatca atttgacacg tccatcttga gctaccacgt cttcaatgcc
     2701 aattcgattg ccaatagtat cataaagtag gacatactct acataagaat ctttcaacgt
     2761 tttttccact aattcacaat acaatcctgt ttctagtttg ttttctaggt gcaaaagctg
     2821 atcttgatat ttccctaagg tgatttctac atgaatatgg attagtccat ctttcattcg
     2881 ataatatatt ttaggaaaat ggcggattcg ttgtttggtt ttcttgctgg gtaaatcttt
     2941 aaagaatccc tctgattgag tttcttcggc ttcataccaa tgattttcta aaatcatacg
     3001 agctaacttt tgacggtgct ctaactgttt tatagaatct atacgatagt gataataaag
     3061 ccagctgata agtccgcata caaaaagagc agtgagaata ctgctccaaa agtatggcgt
     3121 atgaagttga tagaaaaatg tatctaactg aactgcttgc cagttcaccg attgtaacgc
     3181 tctccaatga aaagggagta ggacgactag aaaaactacc agcaatgaaa ttagtacaaa
     3241 atgatagacc aagtgcttat cgttggcttt gattcgctct cctctgtcat gaagcaatgg
     3301 cataaaaatc ctcctttcca cctatcaaaa taattgtgta ttgtagatac gagcctgttt
     3361 atcaaaagtt ggttgagaaa tggcttcata tttctgataa gcgattcgct tttcaaagcg
     3421 taaatttttt tctttcggat aataatgacg tcgatagaga gtgtgtccta acagtttttt
     3481 cgcttctttt gtcaacggat agagatagcg aaacatgcgt ccattgattt tctcaatccc
     3541 tttgtattcg caaaatgcct gggaaagcca atgctttttc tctacctgtt caaagcgagc
     3601 attttcctct aataaaaggc gagcacttcg agggtgtatc ttttcccatg actgcttatc
     3661 acgatagaca cttgtcttga aatacccgca gtaaaagaag ttggacgctt gatagacata
     3721 gccacatttt ccctcaattc catctgccag tgtatataaa aaatgacagt ccgtatgttc
     3781 tttcaaccac ttaattagag ctgaaagagc ttgactgcca aaataattgg tttgattcat
     3841 ttctggaaga aaacacatct ttccaatttc taaataatct gtggtttgaa gggaactgtc
     3901 gggaaagagt ttgcgtatgg tttgtagggg ttgcgtaccc cagcctaatt ccacaacgcc
     3961 taataatttt tcttctgaaa aaatccctag aaagtattta cacaatctag ggagtatctt
     4021 tgaataatgg tattgccgaa taaaagaaat ggcttcatcc ttcggaattt ctttcaaaat
     4081 caatggtgtg tttgtcataa gcaacaccta tttttcactt tcggacgctt cttttttata
     4141 tttctgatga ggttttgtct gtccttttaa tacaagatcg tctgctttca cgtaccaatc
     4201 aacgtctgcc cctcgaaaag tagccgtcgc tacggtatct gccacaggat tgattaattc
     4261 cacttctgcg ttgtagtcaa attctttcaa aggaacagaa gcggggatac tgacttgtat
     4321 catgcgtcct tgtccttttg attttaagtc ataggtacgt tctttaattt cttcggaaac
     4381 cgtaccatct tcattctgga tacgaacctc acgacgcaag gcggaaaatt tcaatgtgcc
     4441 aaatgtctgg tctttttcaa tcacaatacc ttctgctaat ctcatatttt ttcacctttc
     4501 ctttcttatg ctttcaccat atcgtctgcg tgcataatgt aattggtaaa tcctcgattg
     4561 ccaattttat aaccttctgc ggtaatatgt gggttgatga gtttgacttt ttcgtcggat
     4621 tcaaaatgtt tctcgccagc ttcggaggga agaatgacaa caatatcatc tgctcgttga
     4681 atcgttgagt ataaattgta actacgagag agaatggttg gtctgccatt tattcgacgt
     4741 tgttcaatgt tcccttcacc agcatattct aattgtccaa atgttttttc catattggga
     4801 atgacatatt taagttccat atttttacct atcctttctg tttttatgtt tgaatgaatc
     4861 ttatttgtgt gatggtttta aaggggggag agcgaccttt tgattcttga ttttttattt
     4921 tcataagttc acttcctttc aaaattgggt aaaaaaatag acgctccgta ctgagcgtcc
     4981 gattcctact atatttaaaa caacgactac ctaggtattt taaatattat aatcaaattc
     5041 tattttatct aataattgag tgggataaag caagtctcct ttactcgtaa aataacccac
     5101 ctctgagaaa agaaataaat tattttttgc tcttgaacaa attacgtata gtagttttct
     5161 cgctgaacta attcctttat cagaaacatt aaaaatttca ttccaatgag gaattttccc
     5221 gtttagaaga ttaatagcga taacagtatc atactcattt cctttaactt tatgtgctgt
     5281 agtaagtgtg ataccatctc gagatttaaa catcttctta aaactagata cactactaga
     5341 taatgaatta ttttttatcc gatcttctac ttcgttaata aaaaatagat agtgcttaaa
     5401 aatagacggg taatttttct cgtcaatatt aagattaaca aatatatgtt tggtaacaaa
     5461 tttgtataaa tcaacaccgt tgtcgtctcc actatacatt cttttcacac tgtttattag
     5521 ctgtaataaa tctaagtcaa taaaataatc tttaacttct attccaaatt cattttttaa
     5581 t
//
LOCUS       DARBDN010000129         5532 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000129 DARBDN010000000
VERSION     DARBDN010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.133"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..985)
                     /locus_tag="SCH06_002588"
     CDS             complement(<1..985)
                     /locus_tag="SCH06_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HEG1079114.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIG"
     gene            1137..1832
                     /gene="vanR"
                     /locus_tag="SCH06_002589"
     CDS             1137..1832
                     /gene="vanR"
                     /locus_tag="SCH06_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEG1079115.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1810..2964
                     /locus_tag="SCH06_002590"
     CDS             1810..2964
                     /locus_tag="SCH06_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEG1079116.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3179..4147
                     /locus_tag="SCH06_002591"
     CDS             3179..4147
                     /locus_tag="SCH06_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEG1079117.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4140..5171
                     /gene="vanA"
                     /locus_tag="SCH06_002592"
     CDS             4140..5171
                     /gene="vanA"
                     /locus_tag="SCH06_002592"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEG1079118.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5177..>5532
                     /locus_tag="SCH06_002593"
     CDS             5177..>5532
                     /locus_tag="SCH06_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX"
                     /protein_id="HEG1079119.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRG"
BASE COUNT         1669 a         1078 c         1252 g         1533 t
ORIGIN      
        1 ttccgataac cgtgtattga aaggcatctt cgaagccatt atccaatatt tcgcaggctt
       61 ttgtatattt aggctggtcg atatattcac cgactaaggc attcttagct gttcgagcga
      121 gttcaatatc cgtaaactta aagatcgctt ttactgcttc tctaaacggt tttgaattct
      181 tttttggaat ggaactgaag atgtttctta aaaaatggac ctggcatctc tgccaacttg
      241 cgttggtaaa tgacttacga atcgcagaca ctaggccttt atgggcatca gaaatgatga
      301 gttctgtccc ctttaggccg cgttctttta agtattcaaa gaagatggac catgtgtcat
      361 cactttcttc attttgaatc atgaagccaa tgatttcacg gtcgccacct tctgttatcc
      421 cgatcgcaat atggcagctt ttagaaagca ctcgatggtc ctcacggact tttatgtaga
      481 gaacatcagt catcagataa ggataattcg tacctgagag tgaacggttc tgccattcgt
      541 tgaccatcgg gtctaactgc tcagtcaggc tagaaacaaa agatttcgat acagattttc
      601 cacatagctc ttcaacaatc tttgaaactt tacgtgtcga aacgcccgaa acatacatct
      661 caagcattga agcgagcagt gccttttcat ttcgctgata acgctcaaac accgtcggtg
      721 aaaattcacc atcacgtgtt ctaggcactt ttaattcgag tgtacccaca cgagtcgtaa
      781 agtctcgctc ataatagcca tttctttgac tctgacgact ttctgaacgt tcatagtcat
      841 cggcttgaat atattctgtt cgttgatttt ccatcaattg gttgaaaaca gtggttaaaa
      901 tatttttaga aacatcatct tttaccgaat gttcaataat actttgaacc tcttcgttgt
      961 tcagtgtaaa atgtacttgg gtcatgtaac gtcctcctgg gtatgttttt gtggttaaaa
     1021 acattgtacc gtaaaagggc tgttacatgg ccttttatct tttacacaat tatatggact
     1081 ttatcctata atctgataaa ttattaaggg caaacttatg tgaaagggtg ataactatga
     1141 gcgataaaat acttattgtg gatgatgaac atgaaattgc cgatttggtt gaattatact
     1201 taaaaaacga gaattatacg gttttcaaat actataccgc caaagaagca ttggaatgta
     1261 tagacaagtc tgagattgac cttgccatat tggacatcat gcttcccggc acaagcggcc
     1321 ttactatctg tcaaaaaata agggacaagc acacctatcc gattatcatg ctgaccggga
     1381 aagatacaga ggtagataaa attacagggt taacaatcgg cgcggatgat tatataacga
     1441 agccctttcg cccactggag ttaattgctc gggtaaaggc ccagttgcgc cgatacaaaa
     1501 aattcagtgg agtaaaggag cagaacgaaa atgttatcgt ccactccggc cttgtcatta
     1561 atgttaacac ccatgagtgt tatctgaacg agaagcagtt atcccttact cccaccgagt
     1621 tttcaatact gcgaatcctc tgtgaaaaca aggggaatgt ggttagctcc gagctgctat
     1681 ttcatgagat atggggcgac gaatatttca gcaagagcaa caacaccatc accgtgcata
     1741 tccggcattt gcgcgaaaaa atgaacgaca ccattgataa tccgaaatat ataaaaacgg
     1801 tatggggggt tggttataaa attgaaaaat aaaaaaaacg actattccaa actagaacga
     1861 aaactttaca tgtatatcgt tgcaattgtt gtggtagcaa ttgtattcgt gttgtatatt
     1921 cgttcaatga tccgagggaa acttggggat tggatcttaa gtattttgga aaacaaatat
     1981 gacttaaatc acctggacgc gatgaaatta tatcaatatt ccatacggaa caatatagat
     2041 atctttattt atgtggcgat tgtcattagt attcttattc tatgtcgcgt catgctttca
     2101 aaattcgcaa aatactttga cgagataaat accggcattg atgtacttat tcagaacgaa
     2161 gataaacaaa ttgagctttc tgcggaaatg gatgttatgg aacaaaagct caacacatta
     2221 aaacggactc tggaaaagcg agagcaggat gcaaagctgg ccgaacaaag aaaaaatgac
     2281 gttgttatgt acttggcgca cgatattaaa acgcccctta catccattat cggttatttg
     2341 agcctgcttg acgaggctcc agacatgccg gtagatcaaa aggcaaagta tgtgcatatc
     2401 acgttggaca aagcgtatcg actcgaacag ctaatcgacg agttttttga gattacacgg
     2461 tataacctac aaacgataac gctaacaaaa acgcacatag acctatacta tatgctggtg
     2521 cagatgaccg atgaatttta tcctcagctt tccgcacatg gaaaacaggc ggttattcac
     2581 gcccccgagg atctgaccgt gtccggcgac cctgataaac tcgcgagagt ctttaacaac
     2641 attttgaaaa acgccgctgc atacagtgag gataacagca tcattgacat taccgcgggc
     2701 ctctccgggg atgtggtgtc aatcgaattc aagaacactg gaagcatccc aaaagataag
     2761 ctagctgcca tatttgaaaa gttctatagg ctggacaatg ctcgttcttc cgatacgggt
     2821 ggcgcgggac ttggattggc gattgcaaaa gaaattattg ttcagcatgg agggcagatt
     2881 tacgcggaaa gcaatgataa ctatacgacg tttagggtag agcttccagc gatgccagac
     2941 ttggttgata aaaggaggtc ctaagagatg tatataattt tttaggaaaa tctcaaggtt
     3001 atctttactt tttcttagga aattaacaat ttaatattaa gaaacggctc gttcttacac
     3061 ggtagactta ataccgtaag aacgagccgt tttcgttctt cagagaaaga tttgacaaga
     3121 ttaccattgg catccccgtt ttatttggtg cctttcacag aaagggttgg tcttaattat
     3181 gaataacatc ggcattactg tttatggatg tgagcaggat gaggcagatg cattccatgc
     3241 tctttcgcct cgctttggcg ttatggcaac gataattaac gccaacgtgt cggaatccaa
     3301 cgccaaatcc gcgcctttca atcaatgtat cagtgtggga cataaatcag agatttccgc
     3361 ctctattctt cttgcgctga agagagccgg tgtgaaatat atttctaccc gaagcatcgg
     3421 ctgcaatcat atagatacaa ctgctgctaa gagaatgggc atcactgtcg acaatgtggc
     3481 gtactcgccg gatagcgttg ccgattatac tatgatgcta attcttatgg cagtacgcaa
     3541 cgtaaaatcg attgtgcgct ctgtggaaaa acatgatttc aggttggaca gcgaccgtgg
     3601 caaggtactc agcgacatga cagttggtgt ggtgggaacg ggccagatag gcaaagcggt
     3661 tattgagcgg ctgcgaggat ttggatgtaa agtgttggct tatagtcgca gccgaagtat
     3721 agaggtaaac tatgtaccgt ttgatgagtt gctgcaaaat agcgatatcg ttacgcttca
     3781 tgtgccgctc aatacggata cgcactatat tatcagccac gaacaaatac agagaatgaa
     3841 gcaaggagca tttcttatca atactgggcg cggtccactt gtagatacct atgagttggt
     3901 taaagcatta gaaaacggga aactgggcgg tgccgcattg gatgtattgg aaggagagga
     3961 agagtttttc tactctgatt gcacccaaaa accaattgat aatcaatttt tacttaaact
     4021 tcaaagaatg cctaacgtga taatcacacc gcatacggcc tattataccg agcaagcgtt
     4081 gcgtgatacc gttgaaaaaa ccattaaaaa ctgtttggat tttgaaagga gacaggagca
     4141 tgaatagaat aaaagttgca atactgtttg ggggttgctc agaggagcat gacgtatcgg
     4201 taaaatctgc aatagagata gccgctaaca ttaataaaga aaaatacgag ccgttataca
     4261 ttggaattac gaaatctggt gtatggaaaa tgtgcgaaaa accttgcgcg gaatgggaaa
     4321 acgacaattg ctattcagct gtactctcgc cggataaaaa aatgcacgga ttacttgtta
     4381 aaaagaacca tgaatatgaa atcaaccatg ttgatgtagc attttcagct ttgcatggca
     4441 agtcaggtga agatggatcc atacaaggtc tgtttgaatt gtccggtatc ccttttgtag
     4501 gctgcgatat tcaaagctca gcaatttgta tggacaaatc gttgacatac atcgttgcga
     4561 aaaatgctgg gatagctact cccgcctttt gggttattaa taaagatgat aggccggtgg
     4621 cagctacgtt tacctatcct gtttttgtta agccggcgcg ttcaggctca tccttcggtg
     4681 tgaaaaaagt caatagcgcg gacgaattgg actacgcaat tgaatcggca agacaatatg
     4741 acagcaaaat cttaattgag caggctgttt cgggctgtga ggtcggttgt gcggtattgg
     4801 gaaacagtgc cgcgttagtt gttggcgagg tggaccaaat caggctgcag tacggaatct
     4861 ttcgtattca tcaggaagtc gagccggaaa aaggctctga aaacgcagtt ataaccgttc
     4921 ccgcagacct ttcagcagag gagcgaggac ggatacagga aacggcaaaa aaaatatata
     4981 aagcgctcgg ctgtagaggt ctagcccgtg tggatatgtt tttacaagat aacggccgca
     5041 ttgtactgaa cgaagtcaat actctgcccg gtttcacgtc atacagtcgt tatccccgta
     5101 tgatggccgc tgcaggtatt gcacttcccg aactgattga ccgcttgatc gtattagcgt
     5161 taaaggggtg ataagcatgg aaataggatt tactttttta gatgaaatag tacacggtgt
     5221 tcgttgggac gctaaatatg ccacttggga taatttcacc ggaaaaccgg ttgacggtta
     5281 tgaagtaaat cgcattgtag ggacatacga gttggctgaa tcgcttttga aggcaaaaga
     5341 actggctgct acccaagggt acggattgct tctatgggac ggttaccgtc ctaagcgtgc
     5401 tgtaaactgt tttatgcaat gggctgcaca gccggaaaat aacctgacaa aggaaagtta
     5461 ttatcccaat attgaccgaa ctgagatgat ttcaaaagga tacgtggctt caaaatcaag
     5521 ccatagccgc gg
//
LOCUS       DARBDN010000130         5511 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000130 DARBDN010000000
VERSION     DARBDN010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.134"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            377..934
                     /locus_tag="SCH06_002594"
                     /pseudo
     CDS             377..934
                     /locus_tag="SCH06_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            992..3031
                     /locus_tag="SCH06_002595"
     CDS             992..3031
                     /locus_tag="SCH06_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HEG1079120.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFNNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(3140..4291)
                     /locus_tag="SCH06_002596"
     CDS             complement(3140..4291)
                     /locus_tag="SCH06_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEG1079121.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4445..4975)
                     /locus_tag="SCH06_002597"
     CDS             complement(4445..4975)
                     /locus_tag="SCH06_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEG1079122.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(5074..5424)
                     /locus_tag="SCH06_002598"
     CDS             complement(5074..5424)
                     /locus_tag="SCH06_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEG1079123.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT         1996 a         1015 c         1037 g         1463 t
ORIGIN      
        1 tttcaaattc cattgcctaa tcattaggaa aagtctatca tgaactcgta aatagaatat
       61 agtaataacc ttgttaggtg aggctcctat acaaacatag gctgttgccc agaaacgtcg
      121 aaagtcgcca atgggtaaaa cagaaactgt tggattaagg ctttttccaa tagctaagaa
      181 tgttttcttt acgttgtata gtgctaaaac tcggacgatg agatgatgct aggtcagaat
      241 tcttgttcga aaaggtttct gaccttttct ttatattttt gtgactgact tatttgatga
      301 gacaaactcg ctcctcacct gacaagtgga ttgctgtgtg aggaggagat gcggtgaaaa
      361 aagatcgatt ggtggaggtc gctcggattc acttctggtt gcacaataca accagaaaac
      421 acaacaagca aaactgatct ctatcatgag agattcatat gtcgatattc caggttacgg
      481 aatgaataag ataaatgcag cttactctta tgggggagtt gatttattaa atcaaacatt
      541 aaaggaaaat ttcaaatttg aagctcccta ttatgcaagt atcacatttc aagattttat
      601 cgattgcgtt aatgaactgt ttcctggtgg agtcaagatc gatgcagaaa aatctctaga
      661 tttagatggc gtatatataa acaaaggaga gcaagtgatg gatggtaata ctttactcca
      721 gtatgctcga tttcgggaag acaaagaagg agacttcggg aggatcagaa ggcagcagca
      781 agtgatcaaa gctatctctc agcagctgaa agacgtaact tcaatattca agctacccaa
      841 agcggttggg aaattacttg gtagtatcca aacgaacctt ccagaaagtg tgcttctgga
      901 ttgtggtatg gatttcctca aagacatatg ttagaataaa caggtataaa tagtgaaata
      961 aaggaatgac aagcaagaga aggaggaaaa aatgaaaaga agtgacaagc acggcaaaaa
     1021 tcgaacaggc gcttatattg ccggcgcagt gatcttaata gcagctgcgg gtggcggtta
     1081 tttttactac cagcactatc aagaaaccca agcagtagaa gctggagaaa agacagttga
     1141 gcaatttgtc caagctttga acaagggaga ttataacaaa gctgcagaaa tgacatcaaa
     1201 aaaggcggca aataaaagtg cattatctga aaaagagatc ttagataaat accagaatat
     1261 atacggtgct gctgatgtca aaggacttca gatatcgaat ctaaaagtag ataaaaaaga
     1321 cgattctact tacagttttt catataaagc aaagatgaat acctcattag gtgaattgaa
     1381 agatctttct tataaaggaa cattagacag aaatgatggt caaaccacga tcaactggca
     1441 acccaacttg gtttttccag aaatggaagg aaatgacaaa gtaagcctga ccacacaaga
     1501 agcagcaaga gggaatatta tagatcgaaa tggtgaacca ttagcaacaa caggcaaact
     1561 aaaacaatta ggagtcgttc caagtaaact tggagatgga ggcgaaaaaa cagccaatat
     1621 caaagcgatt gcttcctcct tcgacttaac agaagatgct atcaatcagg cgatttcaca
     1681 aagctgggta caacccgatt actttgtccc attgaaaatc attgatggag caacgccaga
     1741 acttccagct ggagctacca ttcaagaagt agacggcaga tattatcctt tgggtgaagc
     1801 agctgctcag ctgattggtt acgtgggaga tatcacagca gaagatattg ataagaatcc
     1861 agaattaagc agtaatggaa aaatcggtcg ctcaggtttg gagatggctt ttgataagga
     1921 tcttcgtggg acaacaggtg ggaaattaag cattacagat gcagacggtg tagagaaaaa
     1981 agttctgatc gaacatgaag ttcaaaatgg caaagatatc aaattgacaa tcgatgcgaa
     2041 ggcacaaaaa atagcttttg acagtctagg aggaaaagct gcatcaactg ttgcgacaac
     2101 gccaaaaacc ggtgatcttc ttgcgcttgc tagctctcca agctatgatc caaacaaaat
     2161 gacaaacggg atctcacaag aagattacaa agcttatgaa gaaaatcctg aacatccatt
     2221 catcagccga tttgcgacag gttatgctcc tggatctacg tttaaaatga ttacagcagc
     2281 aatcggtctc gacaacggca ctatcgatcc aaatgaagtg ttgacgatca acgggcttaa
     2341 atggcaaaaa gacagttctt ggggatcttt taaaacaacg cgtgtcagta gtgatgtatc
     2401 acaagtagac ttaaaaactg ctttgatcta ttccgataat atatatgcgg cacaagaaac
     2461 gttgaaaatg ggtgagaaaa aatttcgtac aggcttagat aaattcattt ttggtgaaga
     2521 ccttgatttg ccaattagta tgaatccagc acaaatttct aatgaagata gctttaactc
     2581 agatatcttg ctagctgata ctggatatgg acagggcgaa cttctaatta ctcctatcca
     2641 gcaagcagca atgtattctg tttttaacaa caatggcaca cttgtctatc ctaaattgat
     2701 tgcagataaa gagacaaaag ataagaagaa tgtcatcagc gaaacagcag tacaaacgat
     2761 cgtgccagat ctgagagaag ttgtgcaaga tgtaaatggt acagcacatt ctctttctgc
     2821 tttagggatt ccgttggcag cgaaaactgg tacagcggaa atcaaagaaa aacaggatgt
     2881 aaaggggcaa gagaacagtt tcttgtttgc tttcaatctt gataaccaag gttatatgat
     2941 ggtcagcatg ttggaaaata aagaagatga tgattcagca accaaacgag catcggaact
     3001 attgcaatac ctcaaccaaa attatcaata aaaaattgct ttttaagtac agtaaaagga
     3061 ctgtggcgtt atcgtcacag tccttttttc aaataaacgg ttttcacgat gtctctttca
     3121 caacttcttt ttgatttact cacacttcat aaactttttt tgtaaaatat ttgagaacaa
     3181 gtggagaaat aagtgtactt aataaaatca cgataactaa aggtgaatag tactgtggtt
     3241 cgatcaattg actttgctgt ccaatttgta aaatgatcaa agccatttct ccacgcgaaa
     3301 tcataccagc accgaccatc aatgaactat gttgagaaaa accggcaatc tgagcaccaa
     3361 aataacctcc aagcaatttg gtcaaaatcg ctacaagcgt caatatagaa ataaagagta
     3421 gttgttcact aaagtcagaa aaatcaactt ctaatcctac actgacaaaa aatactggta
     3481 taaatactgc atatcctaaa gcctctacat tgtggtatac ttcttcttta acctttgtct
     3541 gactgacagc tatcccagca aaaaaagcac caatgacaga gctaagccca acaagatccg
     3601 ctacgtaaga cattcctaaa caaataacta gcgatacgat gataatagaa gaatttgcgt
     3661 acactttttc tgcaaatgaa agtaggaaag gcgcaatcca tttgactaat aagaaaataa
     3721 aaacaaaata aattagctgt tcaatcaaaa caagcggtaa agaagcattg ctagaagctt
     3781 cccccgttag aaaagatagg ctgaaactta gaactaaaac gactaaaatg tcatctacca
     3841 cagaagcacc caaaattgtt gatccttctt ttgtattcac tacgtttagt tcttttaata
     3901 cttctactga aatactgaca gaagttgccg caagaataat cccaaagaaa atcgcttcat
     3961 ttcccgaaac ttggaatgct ttgcctgtca accagccaaa aacaaccggg aagatgatcc
     4021 caagcaaagc aacgaacata ccaggtcgga aatatttttt caaaagagat aaatcacttt
     4081 ccagaccagc taaaaacatt aataagatca caccaatctc cgaaaagtca tggactagaa
     4141 tatcaggttt gacccaattc aatccagctt ggcctagcaa aacaccaaca agtaattgtc
     4201 caatcactgc tgggatacct aatctccgcg agatatgtga gccaatcgtt gttgaaatca
     4261 atatcaggca taaaatacca ataaattcca ttctcatcat tcctttgtat aaaatatagc
     4321 ccgaacttag cataacatac attattgaaa aaataggaaa atatactcac aaaaaaacca
     4381 acaatccaaa agattttttt ggattgttgg tttttatacg gtctatttta ataactaaaa
     4441 atgattaacg tatagtcatt tttcttattc tgatgaaatt gataatctcc tggatgccca
     4501 tgaaaatcaa aataaagccg aatatttgga atagaagcat caaacttttg aatggattga
     4561 acaataagac gaatccgcca atcaacaaca gaatactact ataaacactc caacttttag
     4621 cttttgtatt catgctgaag aacaactgga acaagctgtt gatgataaca gctaatccaa
     4681 gaagaatcgg caggatagaa acgattgcag gtgcaaaagc atagacgatc agagctaaga
     4741 tcaggaaaaa aagaccactg aacagaccga tactccaaga acctgttttc cttttaaaac
     4801 ggtaagcctc aaaaagattc aacaacccaa gcaaaacaag ataggcggtg atcagataac
     4861 cgataaaatg aaaaacagca gaagggttta gcacaatcgc aatcccagaa ataatataaa
     4921 cagcagctct taataaggcg tatttttgaa tattttgttt aatcgtctca aacatataag
     4981 aaaacctcct ttgacttatt ttaacgtgaa ctagtcattt taccaaatta aatgttacaa
     5041 aatgagcgaa ggagaagaat atctctggaa aaatcaactt ctgaggatct tttccatttt
     5101 tttgcctttt gctagctcat cgatcatttt atctaaataa cgaatttctt tcatcaagtt
     5161 atcctcgatg tcttctactc gtacaccaca aacaacacct gtaatcaagg aacgtgaagg
     5221 attggggaca ggggcttccg caaaaaattg ttcgaaagtc acttgttttt gtagttgata
     5281 ttctagttct gtttgggaat aacccgtcag ccaacaaatg atttcatcta cttcctcttt
     5341 tatacgatct tttctctccg cttttgctac atacatagga taaacgcttg caaaacttgt
     5401 cgtaaaaata cgattttgcg ccataatcag tcacctttct ttttttcaaa ttatttacta
     5461 cttatagtat ataagaaaaa gagaagaaaa agcgattatt caaaaaaaca a
//
LOCUS       DARBDN010000131         5440 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000131 DARBDN010000000
VERSION     DARBDN010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.135"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            132..1064
                     /locus_tag="SCH06_002599"
     CDS             132..1064
                     /locus_tag="SCH06_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079124.1"
                     /translation="MIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEEDK
                     KSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEVVY
                     KNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLS
                     EKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVS
                     ESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGL
                     ETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            1285..3048
                     /locus_tag="SCH06_002600"
     CDS             1285..3048
                     /locus_tag="SCH06_002600"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HEG1079125.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            3132..3590
                     /locus_tag="SCH06_002601"
     CDS             3132..3590
                     /locus_tag="SCH06_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEG1079126.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            3699..4382
                     /locus_tag="SCH06_002602"
     CDS             3699..4382
                     /locus_tag="SCH06_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEG1079127.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            4529..5143
                     /locus_tag="SCH06_002603"
     CDS             4529..5143
                     /locus_tag="SCH06_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEG1079128.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            5159..5365
                     /locus_tag="SCH06_002604"
     CDS             5159..5365
                     /locus_tag="SCH06_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079129.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
BASE COUNT         1949 a          855 c         1111 g         1525 t
ORIGIN      
        1 attatttgaa aaataaagaa atcattatcc cagaatttga ctcgcggaac atcttgctag
       61 ctttagtacg ttatgtcaat tgggaaggct atgaaaataa aaatccgtat gtagaagaag
      121 cttgtaacga gttgattgat tatgtagaga ctcatttttt taaaagaaga tattcggaag
      181 atgaaaagtc ctttatcata cgaggaatag agatcgcaat cggaagaaag gcatttcccc
      241 ttggactgaa agaagaagat aagaaaagcg cagaaacgaa gccgttattt caattagtct
      301 gtcaaggatt ggaagagcaa aaaggaattc tagacttaca agaagaagat gtctattata
      361 ttttttcttt gttcaacagt agaaattata ccaatgagaa catggagctg ttaagaaaag
      421 atttcgaagt tgtttataaa aattttgttc tcaatgacct atcactgaat gaattgattt
      481 tacagattat tagtatcgct gaaatcgacg atgcagaaaa ttttattttc aagcaatcct
      541 ttttacaatt tgtccgtacg ttgtgggcag atggacaagt atttttaccg gaaaggatct
      601 atcttctatc agaaaaagaa caacttctgt acggaaaaat tgtagaaata ttggaagagt
      661 ggaaaaagaa aaatcaaatc caactaagat ggaatgaaaa tttcattcga aaattcgtca
      721 aaagtctttc tttgatcaac agtgaacaag cggggagaca ggaaatagaa atttttgttg
      781 tttcagaaag ttcagtcaaa caattttttt atcgaaccca atttcatttg tatgcggaag
      841 aaggcatcgc tgaaataaat cctattttat ttcgttcatt agaagaattg cctgatgaat
      901 gtctatgtgc gaaaaaaaga gtggttttgt gcgatgctgc tagctatcaa aatggattag
      961 aaactgaaaa gacaaagatc tatccaatct cattaaaagg tgcaaacatc catttgtatc
     1021 atattgctca ggaacttcac ctattaaaaa aacatatttc ttgatgagac cttaattagg
     1081 agaccttcta caaagctttt taattgtctg tagaaggttt ttatttgagt cctgattcgt
     1141 gcgaagatct acttatataa caagctttct ctgaaatttt tttaaaatgc tattgactta
     1201 gagtcaactc taagtagtag aatagataaa gtgtaacaaa tctattttca ttaaaagaag
     1261 atagtacgga ggagagaatg tattatgagt acagtattac atgtattgga tgcaatcaat
     1321 agccccgcag atgtcaaaaa attatctgtt gaggaaatga aacagttggc agaagagatg
     1381 cgccaaaaaa tcttgcaaaa ggacagcgat gtaggtgggc acgttggtcc gaatctaggt
     1441 gtagtagaat taacgattgc gtttcattat gtatttgatt caccaaagga taaaatcgtt
     1501 tgggatgttt cccatcagtc ttatggtcat aagcttttaa ctggtcgaaa aaatggtttt
     1561 gaaaaaggac attaccgtga agtgagcgga tattccaacc aacatgaaag taaacatgac
     1621 tattttacag tggggcacac atctacatct atcagcttag caacaggttt agctaaagcg
     1681 agagatctga agaaagaatc aggaaatgtg gtagcattta tcggtgacgg ctccctaagt
     1741 ggtggcttag cttttgaagg attgaacaat ggtggtgttt tacaatccaa tctaatcgta
     1801 ttagtaaacg ataatgagat gtctattgat gagaatcatg gcagtttata taaaaactta
     1861 gctgagcttc gtcaaaccaa cggtaaaagc agcaataacc tatttaaagc aatgggattt
     1921 gattatcgtt acgtggataa tggaaacgat ctggaaacgg tgatccgttt atttgaagaa
     1981 gtaaaagata ttgatcatcc gattgtactt cacgtccata cggaaaaagg tcgcggttat
     2041 cagccggcaa tcgataataa aatgaaatat cattggcatg taccatttga tctgtccacc
     2101 ggggaggcaa agcaagtaac ttctggagaa acatttaata tgatcatcat ggattatttg
     2161 gataagaaaa tgcaaacaag tacagctcct attgccgcag tcaatgcagc gataccaggc
     2221 gcctttggac tgaaaacatt ccaagaaaaa catccagatc attattttga cgtggggatc
     2281 gctgaacagc actctatcac tttcgcttct gctttggctt ctcagggagt acgtccagtc
     2341 gtcttccaat caagtacttt cttgcaacgg gcatatgatc aattatcaca tgatttagcg
     2401 atcaacgaga atccagtgat tattttagtc ggtggcggaa cgatctcagc tagtgaccga
     2461 acacaccaag gaacatttga cattccttac ttatcaagta tcccgaacat caaatatctt
     2521 gctccagcaa caaaagagga tatgatctct atgctagatt gggcgttcga acaaacagcg
     2581 cagcctgtag caatccgaat tcctacacat ggtgtagaac atggtacagc tatcgcaaat
     2641 gattatagta ttccagccta tcaaacagta aataatggag gaaaagtagc aattttagct
     2701 ttaggcggtt ttcttgaatt aggaaaagaa acagtaaaag cttttagaaa aaaaggaatc
     2761 gaagcaacgt tgatcaatcc aggaacgatc acagaaaatg acgtagaaac attagataaa
     2821 ttaaaagaaa cacacgaatt agtcatcaca ttagaagatg gtagtttgtc aggaggattt
     2881 ggcgaaaata tcagtcgtta ttatggtgat tcttcaatga acgtattaaa ttttggtgca
     2941 gagaaagaat tcacggatag cgttcctgta gggcagcttt atgaacgtta tcatttaaca
     3001 ccaaaacaaa tcgttgaaga tagtctgcgt gtcttgaata ttcaataatt cattatgctc
     3061 accatccaga taattgttta tactagtatc tggatggttt tttcattata aaaagcaaag
     3121 gggtggatgt tatgtatcag caagtagaag aatatgtcaa aaagttccaa gaaaaatatc
     3181 ctagttatca atcagaaaaa ttaggtttct tttcatttgg ggatacagaa aaaatggcag
     3241 acgagttgag cgaactagtt gtaaaaaaga taaagactgg tacatcaagt ggttacgatc
     3301 tgtataaaca agagaatgag cctttaccaa aagttggtca attagacgtg gtcctgaatg
     3361 gaaaaaatga accagtttgt atcatcaaaa atataaatgt gaccatcttg ccttttagtg
     3421 aagtcacgaa agagcatgct tggaaagaag gagaagggga tcggacatta gcttattggc
     3481 ggaaagtcca tgctgagttt tttaaacatg cttataaaga agcgttgaac atagaattta
     3541 cagaagagaa gctggtcgta tacgaagaat ttgaagtaat tttcttttag taagaaaggt
     3601 ctgctgaaag aaatagctca ttattgtctc ctgaatagaa aagggttaca tttttatatg
     3661 aagctgtatt tttatataac attactggag gagatattgt ggatacactg gaacaaatca
     3721 aaggcggagt cgtcgtttct tgtcaagctt tggaaaacga gccgctacac agttctttta
     3781 ttatggggag aatggctttg gctgcaaaag aaggcggagc agttggtatt cgagcaaata
     3841 cgacagaaga tatcaatgaa atcaagcgaa tcgttgattt accggtaata gggattatca
     3901 aaagagatta cgatgggtca gaagtgttta ttactgcgac agaaaaagaa gtggaagaac
     3961 ttttggagac gcaagcagaa atcattgcac tggatgcaac ttctcgtaaa cgtccgacag
     4021 aaaaaacaac tgctgaactt gtccaaatga ttcacgaaca cggtcggtta gctatggcag
     4081 atatttcgac ttttgaggaa gcgcttcaag cgcaagaaga tggttttgat cttttgtcta
     4141 cgactttagc aggctataca gaatattcac gaaagacgca gacacctgat tttgatttat
     4201 tgaatcaaat catagaacaa gtcgatatcc cagtaattat ggaaggacat actgactctc
     4261 ctgaacaagt agagaaagca tatgaattag gtgctttttc agtcgtagtt ggatctatta
     4321 tcacccgtcc gcaattgatc actaaaagat atgtcgaagc cgcaagtaaa gcaaataact
     4381 aaaaaacacg cacggcacag attcttgaca aaaaagaaaa attgatagat agtttaaagc
     4441 agattctaag aagatgaaaa aagcattact tttcattttg tcttcaagat ctgcttttta
     4501 acgaatttta tagaaagaag gcgaaaccat gtttgaacgg agtccttcag aattgacaga
     4561 acgtgaaaat tacaagttgc tgattggttc agtcatccct agaccagtag cagtagtaac
     4621 gactaaatca gcaaaagata tagtgaatat cgcacccttc agttacttca atatcgtcag
     4681 ttcgaatcga cccatcttat ccttggcgat ccagagaaaa caagatgcag taaaagacac
     4741 agcaaagaat attcttgaga caagagaagc tgttatccat atccttgatg aggacaacgt
     4801 agaagaagta aataaaacag cagccaatct gcctaatgag gaaagcgaac tgtacctgac
     4861 tgacttgact ttaactgatt cagtaatcat ttcagtacca gcattgacag aagcaaaagt
     4921 tcgttttgaa acatccttat atgaacatgt cgagatacgg aataaaaata aagtaacagc
     4981 tgatttattt ttgctagaag tacagaaata tcatttaaat gaaacagtct atgatgataa
     5041 gacaggaagg atcgatccaa gaaaattgaa tgctgtaagc cgtttggcag gaaatgatta
     5101 tgcagcaata ggagaaattt tcacgattgc acgtcccgaa taaaaaggag cactagttat
     5161 gttaaaaata agctataaac catcgacaga ttcaaaagaa atgaaaaaag aatatgaaac
     5221 agtgaatgat tttctgcaag ggcagtactt agaagttccg ccattgcaag accattttgt
     5281 cgttactact gttactttag atggtaagga aatagaaatg ccagatcaaa cgattagcgg
     5341 attgtttaat tactttaaca aataaatatt tattccgaaa agtgaaaaaa catataaaaa
     5401 aacacataaa actaaaaaat tatcaaagaa tcctggtgca
//
LOCUS       DARBDN010000132         5409 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000132 DARBDN010000000
VERSION     DARBDN010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.136"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(59..2008)
                     /locus_tag="SCH06_002605"
     CDS             complement(59..2008)
                     /locus_tag="SCH06_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEG1079130.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(2050..3108)
                     /locus_tag="SCH06_002606"
     CDS             complement(2050..3108)
                     /locus_tag="SCH06_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HEG1079131.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(3227..3682)
                     /locus_tag="SCH06_002607"
     CDS             complement(3227..3682)
                     /locus_tag="SCH06_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079132.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(4266..5069)
                     /locus_tag="SCH06_002608"
     CDS             complement(4266..5069)
                     /locus_tag="SCH06_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEG1079133.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
BASE COUNT         1568 a         1083 c          753 g         2005 t
ORIGIN      
        1 cttacgaccc atcgttttat tctaaggttt tgtagtaaat atttcttgaa tttcatagct
       61 acgcccctcc aatcgaaaat acaatcttgt tttctttact ttcagcaacg gaaggctttg
      121 caataatttc agcattagaa tcaccttttc cttcaaacgc tccggcttca ctcaacttaa
      181 catcgaatat ttttgcgttt ggataagtaa ttattgcttc agtaatcgct tcttcaaact
      241 cagattcaac taaatgcaag atattccttg caccccctga tttagaatcc tcttgtgaag
      301 ccatgtcaaa aactaagtgc atggagagat cgtctgcata aaaattttga ccatatactc
      361 tttctttcct aggtggaaga cgtaaatcta tatttaaatg ttttcgtact aattcagcac
      421 tcttcaacat ttcattataa gcaatttcca gaagagtttg ttcggataaa gcccaaaatg
      481 gaactattcg tccaaatcgg ttaataactt caggctttag accttcacca atcaaggctt
      541 gtttgatccc tgatgcgact tttcggtatt ctctttttag ttcagtgctg tattcattag
      601 aattttcctt gtttgtaaca cgagatagtg agctatatcg gtttaacgaa tcgaacatct
      661 ccgcacctgc atttgttgtc gcaaataaaa ttgtatttga caatgaaacg gtgtcgtgaa
      721 cttctcgatc atcccatcct ctttcagtaa aacttatcct accttcatct aaaattgata
      781 aaaaggcatc gagtgtttct acaccagctt tctcatattc atcacacaca ataatcgcag
      841 aaggatcatg ccttacatga gtacctataa gtcgtctaaa acgcattgca tcatctttgg
      901 ttttgtagtc cggcatatta actaagagaa ctttattttc atcgccataa agtcctcttg
      961 ccacggcttt agccattgca gttttaccga cccctgttga tcctgtaaac agagcagttg
     1021 cttttggttg ctttcgacct ttaaaacgat caaatccaag cttcatacgt ttaaacaaca
     1081 ttgttatagt ataaactgct aacggttgtc cttttatgga ctttaattcc tcttgaagtt
     1141 tttccatatc aaaatcagaa tctagctgaa tattatactt accaaatatt tgcaatagac
     1201 tttctcgatt ataagcattt ccgtctactc gatcttttgc aatcaaatcc tccattacag
     1261 caattgattt agccggttcg gacaaatcct cacgataaag tttgtttgct tgtacgattt
     1321 cttgaagtaa ttcatcagga atcctttgcg ataatctaaa agaagcctga ggatcatctt
     1381 taacagagga tgtatttagc cattgtctca aaatatcgac gacaacatcg ctttttagtt
     1441 cattcaattc taacggttgt agccgtctcc ctaaggcatc atctcttttg atatagtttt
     1501 catattcttt tcttgtagta gcggtaatca tttgaagtga ttcatttgct aacggttctt
     1561 ttagcgaatc acccccaatt ttattgccac tcccaaaaga gctaacaact ttatgaaact
     1621 cgtcaatgaa gaggacaaat tcattatctt tgtcctcagc ttttaaaatt cgctcatatt
     1681 ctttcaatct tggaattaat gtttctaaac gtgtttggag gacatcatct cccccaacac
     1741 gcaattgtcc gattgataat ttatatactt gtactttctt tccatcttgt cgctgtcttt
     1801 cagcccattc acttgcaagt gctgttttac ctgttccggc ttcacctaac aagatagctt
     1861 gcggtgtttc cggtctattc aagatcagtg acaactcatg gagttcgtca tcacgtccca
     1921 ctaacttatg ttttggtggt ttcattggtg tgagagcatg attaaattcg gtttgaatat
     1981 tcttaaaaaa ctcggtacta ttttccatct gtttgtgttc acttcctcta aaataagaat
     2041 aatttacttc tagtcagtca aagttaggta cttaaatgtc gtcttcatgt ctccaaaaga
     2101 atctttgtta aagtcagcat ttttgtattg atcaatcaat ttttgtgtat cattgattgc
     2161 tttaatttcg gtctccattc gactgtctag ttgacgaata ctttcttgcg aatctttatc
     2221 gtcaggattt tgttgtaaac gttccagata ctcagctttt gtggcttcaa ttttcttgat
     2281 gttagtattt gaagcattta actgatcttc tagcttattt acaacattat tcttacttgt
     2341 aactgctaca acttttgaat aatcaatatc gccatctttg gtaagaaagc ttccttgata
     2401 gacattagtt gaatctgaat atggatttat tctgaaattg atattatcag gagtattaac
     2461 aggttttgct tttttcccaa aagaaattac tccttcatta ttaacatcat tcatagaata
     2521 ttgagaaagt gcttttgtaa ctgaatctgc ttcattcaca ttgactttgg tatcatcgtc
     2581 agctgtatca tcaccagaaa ttagtgatac ttggtttgca ataaaaactt gataagctct
     2641 ttcctctaat ttacctttta ggaataagaa agcatcccca tcagtactta acatcccata
     2701 gctcatttca agcttcttag gacgatcttt ttcttttgtt gccatatata agttatagtt
     2761 ttttccttgc gtagataaca actttctagc gttttgggag taaccaagtt ttactactgt
     2821 tacatctcta ttttgatctg tccacacatc tgaaatagtg atttctgctc ctgatcgagc
     2881 aaactccaat gaagacccta taggtgttgt attgttcacg agataataat tatagtttcc
     2941 taattgataa atgtagctac ccaagcctgt taataaaaaa agcactccta gaaaagttgc
     3001 aagcataatg cgtaatccgt gacgtgttct cttatcctta tcaccaagca accctccaat
     3061 aatactgtat tgatctttgg tagatgttga attgacgttt ttttccatca gtttgtctgc
     3121 cccctttcat aaaagagcaa acaatcagac gttttttcgg taattctagg ttcgggattt
     3181 tgaatcattt cggtatattc ttccccatta atatttaaca caaaaattat cttcctttct
     3241 tcgttccttt cttttgctct ttattttcca aataatcaat gatttttgct attgtaccaa
     3301 gatagtaatt cccctcagct ttgttttttc ggattttgct aaccattgga gtaggtacaa
     3361 tctcttcatc tctcaattca ctgaaagatt ttttacctag atattttcca ataacagatt
     3421 ttaaaaaacg ttcaaaatct ttctcgtaag ttgttttctt gccttttagt tcatggttca
     3481 tattgtcaac gacttttgcg gtttcaataa ttgttttagt tctcagctta ataatttcat
     3541 ctggaatttt caatcctcgt aatttcatcg ttgtactaac tggtaaccca tgctttactg
     3601 catcagcaat actaaaactt tttagatcat ctagtaagct ctccatatag ttaacaaatt
     3661 catgccaatt aatagcattc attgtctcac cccttcattt ttttaaaatg aggttcgggc
     3721 gtaacacatt tatgttatta taatatcata ataacataaa taaatcaatc agcaaattta
     3781 gatatccctt aaagtatcag caattattca acaagatatt tattttagct atttcagtca
     3841 tcataaaaga ctaattagca ataaaataac taatattatc catttatcag acgaaaagaa
     3901 aaaacttatc taattactct atattaactt ttaacaaata gttgacttgt ccaaaaatgt
     3961 taccttcaat ctcacaaaga tattaagatg tttcctacca aaactgatat caccggactt
     4021 tttattctgt gttgtccaaa agtgttacct ttagtcgatc aacaaattaa aaaaaattgt
     4081 ttttttcttg acttgtccaa aagtgttacc catagttgtt aaaatttgta tagattagcc
     4141 attctttcga atattattta gactgaaact tgcttacaaa aaaacttctt gcatttattg
     4201 tccaaaagtg ttacccatac ttttttaaag aagcaggttg tattaaaatt acaacctgct
     4261 tcttctcaat cttcttctaa ccaattatgc attgaaatgg ttggcaagtt tgattctggc
     4321 tcactaaaag tgaatctgag ccgatcaact cttcttcctt tctttgcata gattttttca
     4381 taatcaaaag tttcaaatac ctgtattccg ttttcatcag gagctaaaaa ttcttctttc
     4441 gcctgctcta gtattctttt gtcaatattt gtcattctat aacttgaagg tatacttaat
     4501 gctcttctaa aatcttcaac tttgactacc caataaccat ttcgccactc tttatttctg
     4561 tattgcatga gatgacgata caattctttt gtgtagctac ttcttagttt tgtaaaatta
     4621 tcaagttcaa aacgagtaaa gtttttgcca attgagttta agataaattc aaattcctca
     4681 tttgccttaa ttgtaactgt ttccttctgt ttatctatcc ggaatttttg aaaaagccac
     4741 agctgttcat agacgtctga atcttcaaaa cggtaggtta aagtacctag tttgtcactc
     4801 aaagctttta acacagaata aaaactgtcc ttttctcttc tgtcgtattt gaccaaataa
     4861 cgaaagaggt tgaaatcaaa agttacttct gctgttcctt gacgtttcat ttttgataaa
     4921 atagcccaaa acacatccat ttcaacaggc ttaaatcctc gcaaagctgt tgtattcaga
     4981 ccattgttat aacgcacaat tgcatttgtt tgttctgata ctaaatctac atcactatca
     5041 ataatctttt cggtaacttc ttgagacatt gattactctc caatcttctt tttgcgctcc
     5101 tttaatcatg ttaatctggt actaattaaa ggaaacaatt ttttctgctt gttacctaaa
     5161 ttaaatcaca actaaaggta acagtcaaca aagatttgtt actaatctaa ttttctattt
     5221 tttcgccttc caaatcaaga aaaccgaagg taacgtctta tcctagtgtg atacctcaaa
     5281 tgtccacttt tgttaccttt gctgtccaaa agtgttaccc ttactgtcca cttttgttac
     5341 ctttactgtc caaaagtgtt acctttatac ccctttaata cttactctcc caagagatta
     5401 agcctcccc
//
LOCUS       DARBDN010000133         5261 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000133 DARBDN010000000
VERSION     DARBDN010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.137"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(1..354)
                     /locus_tag="SCH06_002609"
                     /pseudo
     CDS             complement(1..354)
                     /locus_tag="SCH06_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(614..1162)
                     /locus_tag="SCH06_002610"
     CDS             complement(614..1162)
                     /locus_tag="SCH06_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079134.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1163..2020)
                     /locus_tag="SCH06_002611"
     CDS             complement(1163..2020)
                     /locus_tag="SCH06_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEG1079135.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2306..2593)
                     /locus_tag="SCH06_002612"
     CDS             complement(2306..2593)
                     /locus_tag="SCH06_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEG1079136.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(2583..2912)
                     /locus_tag="SCH06_002613"
     CDS             complement(2583..2912)
                     /locus_tag="SCH06_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEG1079137.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            3090..3659
                     /locus_tag="SCH06_002614"
                     /pseudo
     CDS             3090..3659
                     /locus_tag="SCH06_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
     gene            3794..4120
                     /locus_tag="SCH06_002615"
     CDS             3794..4120
                     /locus_tag="SCH06_002615"
                     /inference="COORDINATES: protein motif:HMM:NF012464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079138.1"
                     /translation="MKYGYARVSTRHQDLEGQMRQLEEERCDKIFFEKITGTKSDRPE
                     FQKLLQEVQTGDTLVVTKLDRFARSTQDALHTIKLLFEKGVRINVLNLGIIENTSTGR
                     LIIHYF"
     gene            4152..4346
                     /locus_tag="SCH06_002616"
     CDS             4152..4346
                     /locus_tag="SCH06_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HEG1079139.1"
                     /translation="MERTQEGKEIAKQRPGFREGRPKKFSKQQMTLAMKLLETNSYKE
                     VEKMTGISKSTLTRYKRKKS"
     gene            4498..4731
                     /locus_tag="SCH06_002617"
     CDS             4498..4731
                     /locus_tag="SCH06_002617"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079140.1"
                     /translation="MFQSFIHEKQRELSIKMIQALKTFRQSEEAIVNALNYHYSNGLV
                     EGINNKIKVIKRTAYGYRNFSNFRNRIFIEREL"
     gene            4816..>5261
                     /locus_tag="SCH06_002618"
     CDS             4816..>5261
                     /locus_tag="SCH06_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HEG1079141.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDSDTLPMKGKRKPNGHQEKRGKQQYQRSIHDR"
BASE COUNT         1652 a          996 c          841 g         1772 t
ORIGIN      
        1 taaatgttct tactgcctct tccacactaa tttcttcgtt caatttcact aataatactt
       61 gatctcgctt attataatcg ctttcattta tcctaagagt caaatctttt tccaccataa
      121 cttttacacc caataaattt tgcggtttat ttttctctgt tgaaattctt tgtgtagcct
      181 ttaaactgac aattagctca ttgggtacat acttatttga gagtcatcta attggctcat
      241 aatcctttct ttttggttag tatctgcagt tacttgttta gtatgagcca tgaacccaaa
      301 catactcacc ccaacaacca atcctaaata tattttcttt ttaaactttt tcatctacat
      361 ctcctcctaa tagttttatt ttagagttag ctctattact tatttactaa ctcaacaaca
      421 gattatcata cacttgttaa tgaaatcaca atatctcatt aaaacacacc ctaaaatcat
      481 aaccgttcct atgctcattt tttggatttt ttaatcacgt aaccagaaaa ataaatcccc
      541 tctatttcac gcaaatcaaa gaagaactaa gtaactaccg tttaaaggta gttacttagt
      601 tcttctttga ttattatcta actttattat tcattcccca ccctttgcgc agtgagtctt
      661 cggtatcttg ttttatctga ctggtagttc ttattatttc tccacgatca tctaattctg
      721 gaacaattgg atatttttct ctgaacaagt ctagttcttt caccacgtca ttaaacaaat
      781 cttgcttatc ttcttgcgta agattctgtt taatatactc atctaaagct tttctaagca
      841 attcatctct tgtcatatta gtctcatact tttctactaa aactctggaa gtcgcattta
      901 acaaagtcga cagttttaaa ggatgcttgg tggaataaac cttatcaaac tttctgattg
      961 gtgcgccaac tttttttgtt cttcctctac tctgtctttc aacattggag gaagttttta
     1021 tttcttgaac ttggtgcact tctaattgct tattttcaga tggtgtaatt gcttgctgct
     1081 ttttctttgc ttctgcttct ttttttattt tggcgagtcc tttgttgttc ccaaaaatat
     1141 caagtccttt gatgtcagcc aattactcca cctccgcata ccaattctcg tgttcttcca
     1201 attctttcaa aatactgata aataattcgt ggcttttgcg atcccattgt tttaagagac
     1261 ctttctttgt cttctccatc gtaatacctg atccgtcgta tcgttttaag cgcgcatttt
     1321 tgagtacaac atttttaatc aaatgttccc cataaatctc ttgggcttgt ttatacattt
     1381 cctgatctac tgcgtcaccg ctttccaaca tgaaaggaat aacaccagca acatataaat
     1441 ttgtatcaaa ttctttcaca aaaaagtcca tatactcaag atattgcatc gcatttctca
     1501 tcgattttac ttgggtctgt aagacgacga ttgcccagtc cgcaatgtac atcgcggatt
     1561 tactatatac agaaatagaa ggtgggacat ctaaatagat gacgtcaaac tcatcaaata
     1621 atggttctag cttttctttc atatatttga attgggataa tgaatcatta tattggtctt
     1681 tgatccaatc atcatacatt tcaaaggaca tgtctgctgg aagtatatag aggttattga
     1741 ttactttata gacagcctct ttaggtggaa gattgtttat caacacgtca gtcacagtat
     1801 tttcgtaaac aatcggttca ccttctccgc ccccttcttc gttagtgaag ttcatatgcg
     1861 ttaagttcat cacatcagaa gtatttcctt gcatatccaa gtcaattatc aaggttcttt
     1921 ttccttcatt aactgctgat tcaaacccta acatttgcgc gcacgtactt ttacctacgc
     1981 cacctttaaa attaccgatt acatatttct tcgctaccac gttcctacct cttttctttt
     2041 agcaatattc atttgatact attataacat atttattttt agttactacc aaaaaaaaga
     2101 tatatatgta ctaccttata attaataagg aaaaggtagt acataaataa ggaaaagctg
     2161 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
     2221 gagaatactc gcgactttag tcatgtagac gaatcagatt ttcgataaaa aagaagccgt
     2281 ccttcttaag aacgacaaca aatcactaga ttaatttttt caactgttca taaaagtttt
     2341 catgcgttcc acataacaat actggaataa ccttgttttc tataatctcg taagctactc
     2401 tatatgttgt gcccgcatat ttgaacccac tagaccaaat acctgataaa tccccagttt
     2461 tttgttcacc cttatatgga tcaatcgcaa tttcatcata aattaaattc aaaaattttt
     2521 ctttcaatgg cttctctttt agctttttta aatacttaat gacatgtttt gaaggaacga
     2581 tttcataagc caatttctgt tgccaactcc tctttagtca ttactttaga attagtaagt
     2641 gtatcttcag caatatctct aaaggaagaa tgcattttgt tttttctatt cttaaattct
     2701 acaagaatct catctttatc gtagccttct gcaattatat cagacaaaat atcttcgcta
     2761 aaatcataaa attctttttg tggttcaaca aattcataaa gaataccatt ctctaccaac
     2821 tttgcttcaa cttcgactcc attaggaaca ttaaaatctt taggtactgt caacatgatt
     2881 gaattgcctt gttttcttgt ttttgtaatc atttaaatcc ctcatttcta acagtatgta
     2941 attacttagt aaatacatta taccacgaga taatgtattt acaagtaatt actgtgactc
     3001 gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca tcttcatcta ccttatttga
     3061 tagtagattt aaaactttgc aacagaacca ttgtagctat tggggcaaag acttattcag
     3121 ctcactcgat tgccggcagc attgaaagtt ttgtttatat gccagcttat ggattagcta
     3181 ccgctgcagc aactttagca ggaaatagta ttggaaaaaa agactatgtg gaaacaaaac
     3241 gtgttgcatt ttatgcggtt aaatacggcg tgattgtttt aagtatccta ggtataggat
     3301 tgttttttgg tacgccatat attgcacctt ggtttaccac agatgctgag gcaataaagc
     3361 aaattgttat tgcgctaaga attgacgctt ttaatcaacc aggactagct atcagtctaa
     3421 tattagctgg cgtactccaa ggaatgggag atactaaaac cccattatac agtactgcat
     3481 ttggaatgtg ggtcacacgc atattaggtg taatactttt agggaatata ttggatttag
     3541 ggattgctgg agtgtggtta gcaattggca tggatctata tatacgttca ctttttttaa
     3601 tctatcgttt cagacgaaat atccaaattt taaataacaa taacgaaaca ccttcctaaa
     3661 ccagtgattt tttatcgctg gtttttgcca tttagcgatt aaaaaaattg ccatataaat
     3721 agaaaagtaa cacaaggggt acaatggtgt cataactaat ggtcataagt gaagtgaaat
     3781 aaggggtgaa aacatgaaat atggctatgc acgggtgagt acccgccacc aagatctgga
     3841 agggcaaatg cgtcagctgg aagaggaacg ctgtgataaa attttctttg aaaaaataac
     3901 gggaacgaag agtgatcgtc cagaattcca aaaactgctt caggaagttc agactggtga
     3961 tacgttagtg gtcacaaaat tagaccgatt tgctcgtagc acgcaggatg ctcttcatac
     4021 aatcaagctt ctttttgaaa aaggcgtgcg aattaatgtt ttgaatttgg gcattattga
     4081 gaacacgtct actgggcgat taattattca ctatttttag tgcctttgcg gactttgaac
     4141 gcgatttaat tgtggaacgg acacaagagg gaaaagaaat tgccaagcag cggcccggtt
     4201 ttagagaagg gcgaccaaaa aaattttcca aacaacagat gactttagca atgaaactac
     4261 tagagacaaa ttcctataaa gaagtagaga aaatgactgg tattagcaaa agtactttaa
     4321 cgcgttataa aaggaagaag agttaggagc cacagaatac cgatatcatc gtcttttcaa
     4381 aggcatggtg acggaaaggg gaatcgttga ttattttctt tccttggacg aaggtttacg
     4441 ccgccattac aacgtctacc aaacaactgt ctttgccatt aactatcgga accgaaattg
     4501 tttcagtcct tcatccatga aaagcaacgg gagctttcaa ttaagatgat tcaagcctta
     4561 aaaactttcc gacaatcaga ggaagccatt gtcaatgcgt taaattatca ctactccaat
     4621 ggtttagtgg aaggtatcaa taataaaatc aaagttatta aacggacagc ctatggctac
     4681 cgcaactttt ccaattttcg taatcgtatc tttattgaac gcgaattgta aaattaagtt
     4741 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
     4801 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
     4861 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
     4921 caaactattt ataatgtagt caataagttc aagcaaggta agactgctct tgattattgg
     4981 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
     5041 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
     5101 cgaaaagaaa gacctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
     5161 atatttgata gtgacacact accgatgaaa ggtaaaagaa aacccaatgg ccatcaggaa
     5221 aaacggggaa aacaacagta tcagcgctca atccatgatc g
//
LOCUS       DARBDN010000134         5219 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000134 DARBDN010000000
VERSION     DARBDN010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.138"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..1256)
                     /locus_tag="SCH06_002619"
     CDS             complement(<1..1256)
                     /locus_tag="SCH06_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEG1079142.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVV"
     gene            complement(1269..2486)
                     /locus_tag="SCH06_002620"
     CDS             complement(1269..2486)
                     /locus_tag="SCH06_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEG1079143.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(2476..4071)
                     /locus_tag="SCH06_002621"
     CDS             complement(2476..4071)
                     /locus_tag="SCH06_002621"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEG1079144.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            4196..4981
                     /locus_tag="SCH06_002622"
     CDS             4196..4981
                     /locus_tag="SCH06_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HEG1079145.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         1573 a         1023 c          869 g         1754 t
ORIGIN      
        1 actacaaaca cgatatgttg gcccattaat ttttggaagc gattggttcc ttttttctct
       61 tcttgtttct ttgcatattt caacgccgca tctagttttt gacgggttgt aatgattaca
      121 acatttgcat tggcatctgc caacagggtt tcacttaatt ctttggcact tcccgttcca
      181 acgatcaagc tattcgcttt ggcgttcccg gaagaaatcc cagtattaaa ttccgaagca
      241 aattttgtaa actctgtggt ggtttgatta tctaaatctt tgcggtccac taacatgatc
      301 gttcgatcga tccccgattt tcgtgctaaa agcttagtag atacaaaact agtcaacgtc
      361 tttcctgaac cagtcgcatg ccacacatac cctgattgat gtttatttgc ggcaataaac
      421 aaggcttgaa tcgcatgtac ttgataagga tgtaacacca tgagggtttt attgtcttga
      481 tcttcactga cgattgtata atccgcaatc aaacgatgag catccgggat atttaacact
      541 tgtttacaaa actcatataa gttttctact ttttcattgt ctttcgttcg ccaactaaat
      601 aaaaacttag ggtgcaagtc tttcggtaag gcatttgcaa aataccgagt ggtttgttca
      661 ttggaaacca caaacaactg taaggtcgaa aagatattgt tccgaaacat accttcttct
      721 gcatattttt tgatttggtt aaatgcctga taaacaccat cttttgcagt tacttgtttc
      781 agctcgattt ggacaatcgg taatccattg attaataagg tgacgtcaaa acgtcgatcc
      841 cgtgcttcta tgttacttcc acgttttgca atttgatgga ccacttcata agtagagatt
      901 cctccaccaa tgtcttgatt ggaataaagg ataagtgaga cagaacccaa ttgcgaatct
      961 tcccgttcaa tcgtgatccg agccatccca ttttcacctt ttaaccattt cgcagcatca
     1021 aatggggttt tcgttcgcag cagtaattcc gttttgatcg tttcaaattc tttatcggtc
     1081 aaaggaaaat cattcagttc tgcttgatta tttgagataa ttttttggcg taaattgacc
     1141 caaaggtctt cttctgattt tagatccgga cgatacgtcc actgattatg cccttctcca
     1201 agtacacgaa tcaactgttc ttcgacttct gcttcctcac ggtgactaat tttcattctt
     1261 cttccctcct agacaaacat cttttgtaag aagctttttt tcgtttcttt tagtaaatct
     1321 aacttacgtt gatgaagagc gatcgtatca tctagctgtt tgaagaaagt accgattttt
     1381 tgttgttcat cctttacagg aaccttaaca ctgatattct caatatcaga actgttataa
     1441 gaaggcaatg cccctacttg ggagtatctt ggcaaattta tagtttcaaa caatatttta
     1501 ccaaaataga tatcccaagt attattaaat aaataagcca tggtattgtt atctattaag
     1561 aaagggcttg tgaccaaacg ttttctatta agcattattg ctgcgccaac tttagcaaat
     1621 ataatcgctg gcacatcttt tattggcttc cattttttac gctcaatttg ctcattagat
     1681 acataatgat ttgcatttct catttcatac tcattaccaa tgttattcat gtcggaaact
     1741 ttaaaaaatg gagtaccttc agaaccacct tgctcggcat caggaaatcc aattcccgat
     1801 tgagttttac ctaattctcc caacttacgc tcttcccaat cttccgtaaa accaggaaac
     1861 cggatttctg gcacttttgc tccgttttca gggaacattt tttgtaagaa tccttttttc
     1921 gtttccttca gcaaatctaa cttacgctga tgaagagcga tcgtgtcgtc aagttgtttg
     1981 aagaaggtgc cgattttttg ttgttcttcc tcactaggaa acattgctac tatattttta
     2041 aactttttta gagacagaac atgttgacct gttccctctg cttgaataga taattgtcgt
     2101 tggattccat tgttaatacg tcttaagaag aagtcggaat cagcagattt taaagtaaat
     2161 acaggataaa aatagcttat aatccctcta tcaataatgt cattacggtt aaacacaaac
     2221 acatcattat cacttcgact acggaacgtg aaatatcctc taggtagtac aaagtaacca
     2281 atattatttt ctgtagttac ttgccgattt gcaaaatagt cttcttgcaa aactatccct
     2341 ttttgttgag atgaagttag cataggaaat tgattttgta cacttgtctt ttcaacataa
     2401 tctacaacga agtcccccaa cttcctctgt tcccaatcat ctgtaaatcc tgggaaacgg
     2461 atttctggtt gtgtatcatt gctcatgttt gaacacctcc agcgcacctt gtaaccacgc
     2521 ttcattttca ggtgttgttt gcagggaaga gatagcttct aaaagttttt tttctagcac
     2581 ttgctgttct tgtcgtatct tcttgatgtc atttccgaca tgaaccatat caattggttc
     2641 ttcttcttcg aaagtatcta catagcgtgg gatatttaag ttatagtcat tttctttgat
     2701 ttcatcaaag gttgccaaat gagcgtattt ctcgacatct tttctttcag cgtaggtttc
     2761 gaggattttt tgaatgtttt cttccgatag tttattttga tttttccctt taacaaattc
     2821 acgactagca tcaatgaata atacatctcg agtttgacga ttcttcttca acacaatcac
     2881 cgtcgttgga atcgatgtcc caaagaacaa gttcgcaggc ataccgatca cagcataaat
     2941 actgccatct tctagtaatt tttgacggat gaccccttct gcagcgccac ggaataaaac
     3001 tccgtgtggt aagacgatgg ccatggtacc tgtttccttc aaatgataga acccatgaag
     3061 aagaaacgca aaatctgctt tggattttgg cgctaatttc ccataacgat taaaccgaga
     3121 atcatctaag aaagtcgtat ctgctgacca attagccgaa taaggtgggt tcattactac
     3181 tgcatcaaat gtgtaaggtt catctgttgg ccagtcctta ttcaacgtat ccccattgcg
     3241 gagattcatt tcttcggcgt cgacaccatg taaaatcaag ttcatttttg ctagattgta
     3301 tgtcgttgta tttagttctt gcccatgata tttaacgtta tctgggtgtg ttaagtagtt
     3361 acgtacgttt aacatcaatg aacctgaacc catcgttgga tcaaaaacac taaagaatcg
     3421 tcgttccttt tgatcgagcg ttacgatttg cgccatcata tcagaaacca tatgaggtgt
     3481 gtaaaattct ccggctttct tccctgcttc tgaagcaaat tgactgatca gaaactcata
     3541 cgcatccccg atcacgtccc catcgtgttc taaaacatct acatcattca atttcttgat
     3601 gacttcggta atcgtcacat ttcgttgttg ctcatctgtt cctagttttt ttgattggag
     3661 atccacatca tcaaataacc cattaaattg attgtaggta gatgccaatt gcacaaaggc
     3721 tttgtttaga tcgttcaatt ggaacgttgc ttgttttgct tgatccgcta agacgttgaa
     3781 aagatactct ggtgcaattg catatcccaa aatatcaacg attgtggcaa tcagatcttc
     3841 ttttgattct tcatctgaaa gtaattcacg atacaacatt gtttgtttgc ttactgtgtc
     3901 atattcctct aaggattcat ctgctaaaag aaccacttgt tccaacaatc gatcggataa
     3961 atatttatag aaaatcagtc ccaataaata atttttatat tctgacgcat ccattttact
     4021 acggagatta tctgccgcac taaataattt ttgatttaat tctgcaccca aaaagataca
     4081 ctcctatctc ttatttaaag ttgctatata ccctcttatt ttagcatact cccttttaga
     4141 aaaagcaaaa aaaaaagaaa aaatcttatt cttgataaca agctacgtga cgtatatgcc
     4201 taacaaaaat agaacttttg aatcaatctt aaatgaaggt ttaaccacag aaccggcatc
     4261 cattattttt gatgaagtta tcgatgacgt tgaagatagt aagtatcata aaaatttaaa
     4321 agaacttttt tattttgcac tcaacaatgg accaagtttg ttcactggta tatcagtacc
     4381 tgatagtgat aatccattaa ttatggcaaa aatttactta acaaaatggt gtaataaata
     4441 catcagggat aggaataacc cagcattaaa aaaacctctt aaaacatttg gcgaaaaaga
     4501 tgctgcttta actactagag tagcagcaaa tgctaatatt gatgatcaaa aagtattgaa
     4561 tgactacttg cgtggacatt ttttatatat gagcgctgag aacatgaacg gaagtatttt
     4621 agaggaatat ttagccgaag tgttagaacc tgaaggttgg atttggtgcg ccggctctgt
     4681 atatcgagct gttgatttct gttatttagg aacctcacca attcttttac aagtgaaaaa
     4741 taaatacaat acagaaagca gttcgagttc agctataaga gtaggaacaa caattagaaa
     4801 atggaatcgt ttaaataagt cgacaaaaat ttctggtttg gatagcccta tccccaattg
     4861 gaaagcatta atagaaatga ctgaagctag taaggaactg gcagctaagt taactgaaaa
     4921 tagttattta gcttatatta atgaaaaatc cacacgagaa ttatggacac tcgatgacta
     4981 acaatatcct tattagtatc tatccacgat acatggaaaa aattataaac aaacaaaaaa
     5041 actttgaatt tagaaatttc tatcttacct cagatcctta taatatcttt tggatttacg
     5101 aaacaatccc caccaaagct ttaaagtata aattgattgt aaaaaatcca attactaaac
     5161 ttaagaaaaa tcaacactac tttttaggag acgatgagtt tgaacaatta gtttaaaag
//
LOCUS       DARBDN010000135         5192 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000135 DARBDN010000000
VERSION     DARBDN010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.139"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(34..714)
                     /locus_tag="SCH06_002623"
     CDS             complement(34..714)
                     /locus_tag="SCH06_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HEG1079146.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
     gene            1591..1845
                     /locus_tag="SCH06_002624"
                     /pseudo
     CDS             1591..1845
                     /locus_tag="SCH06_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1915..2427
                     /locus_tag="SCH06_002625"
     CDS             1915..2427
                     /locus_tag="SCH06_002625"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079147.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2424..3461
                     /locus_tag="SCH06_002626"
     CDS             2424..3461
                     /locus_tag="SCH06_002626"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1079148.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            3621..3797
                     /locus_tag="SCH06_002627"
                     /pseudo
     CDS             3621..3797
                     /locus_tag="SCH06_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            3852..5162
                     /locus_tag="SCH06_002628"
                     /pseudo
     CDS             3852..5162
                     /locus_tag="SCH06_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
BASE COUNT         1891 a          811 c          970 g         1520 t
ORIGIN      
        1 aatcaaacgc gccctctctg aactccaaat atcttaggct gttattccca ttaatacctt
       61 gatttcagta gacaccgaaa agccgaagag cgttccattt cttcggttct ttttatatat
      121 tcctcgaatg gtctccatgc ccttaatcgt ggaagaggct gtacggagac tttgataaaa
      181 tttatttcgt cgtttaatag gtcgatggtc ttgttctatt aaattgttaa gatacttcac
      241 agttcggtgc tctgtcttag tatataaacc cacactctgt aactttctaa aggcggagcc
      301 aagagaaggt gctttatcgg tcacaattgc tttcggctca ccaaactgtt tatggagtcg
      361 ttttaagaaa gcataggctg cttgcgtatc ccgtttcttt cgtaaccaga tatctaaggt
      421 taagccgtcc gcatcaattg cacgataaag ataatgccaa cgtcccttaa ttttgatata
      481 ggtttcgtcc attttccatg aatagaagga ttgtctattt ttcttcttcc aaagataata
      541 gaggactttg ctgtactctt gcacccaacg ataaatcgta gtatgacaaa catttattcc
      601 acgatcatat aacaattcct gaacttcacg atagcttaga ttgtaacgca ggtagtaacc
      661 aacagcgaca ataatgacgt cttttttgaa ttgtttgcct ttaaaatgat tcattactct
      721 gtcctctctg tcttttttct caattttaca ctaaaataga ttttttggaa aactttgcaa
      781 cagaaccgtt ttattgatga ccacgaaagt gcatggcgat atttgatgtt gatactttat
      841 gcagtaccct atgtattctt cgctatcatt ctgtggctca tagcattgtt ttttagagta
      901 tttaatgacc tttaggtaga tttatatata aaaagggcta aatacgcaaa ataccccctt
      961 aaaatgcaaa ataaatgcaa ataagggggt aactccttat gaaaaaacaa ctaatagtat
     1021 tataacacgt ttttatgccg agaaaactta ttggttggaa tgggctatgt gttagctaac
     1081 ttgttagcga gttggttgga cttgaattgg gattaatccc aagaaagtac caactcaaca
     1141 acacataaag ccctgtaggt tccgaccaat aaggaaattg gaataaagca acgaaaggag
     1201 ttgagtaaaa tgagtgagaa aacgaagaaa atcattcgag tatcattagc tttttcacaa
     1261 gtagtagtgc aatcattgat agtttattat acttaccagc aatataaatt atctaaagag
     1321 aattaagttt tgattatgta ataagttttg gtactaaaaa agacttgatc taattagacc
     1381 aagtcttttg ttagtgttat attaataaca aaataaaaat aagaagtcgc tcactccccg
     1441 accaaagttt gtgagcaaaa taaacagtcg atgtttgttt cttaattgta tatcttgata
     1501 ttaaacgatt taagattatt cttcaagata tatattcgca aatgtaattg gaaaagcgac
     1561 ttcttaaaca aaattaagga gtcgcttttt atggcaaaaa taacgaaaaa tgagcaagaa
     1621 aatttggtgg aaaattacac aaaaaaaccg gcgtactcta atagccggtt agacgcacat
     1681 ttcgtgtgca cttctaatcc gaaattgagc tttgacgcta tgacgatagt cggaaacctt
     1741 aataaaaaca gcgctaaaaa gctatccgat tttatgagtt tagatccaca aattagactt
     1801 tgggatatac ttcaaacaaa atttaaagct aaagcactac aagaccccct atgttaggct
     1861 agttgtcgta taggataata agttataata aagactatac ggaggatgat taccatgaca
     1921 aataaaaaca atgaacgtta ctctaccgaa ctgaaagcga cagccatcaa gaaaatgatg
     1981 ccacccgaaa atagggggat tcgccaatta agtcaaactt tgggcattcc agaagcgact
     2041 ctttattctt ggcgtaaaaa agctagaatt caagggaata ctacacccgg aacgaaaaaa
     2101 aatgtcgaaa aatggtcaag tgaagataaa tttttaattg tgatggaatc attctcaatg
     2161 aaccaagtag aacttgcgga atattgccga aagaagggct tatttaaaga acaaattgag
     2221 gcttggaaga aaacgtgctt atctgcgaat gaacaggaag aaaatcgaac gagagaactt
     2281 gcaactgaac taaaagaaga gaaaaaacaa gcgcgtcaat tagagaaaga attacgtcat
     2341 aaggaaaaag cattagcgga agccgctgct ctcttattac taagaaaaaa agcacacgcg
     2401 atttgggggg accaagagga agaatgattt catcttcaga tcgcaaacaa gctgttgaac
     2461 ttattcaaga agccaatcgc aatggggccc gtctcaccta tgcctgtaat gagctgaata
     2521 ttagcgttcg aacctacgaa cgatggacgc gtgaaggtac gatagcgcat gatcaacgcc
     2581 ctttggcgaa acgtcctgta cccaaaaata aactgacgga tcaagaacgc gaaaaaataa
     2641 tagaaaccgt ttcaaaaaaa gaatttatga atttgccacc tagccaaatt gtaccaaaac
     2701 ttgcggattg ctcgatttat attgcatcag agtctagctt ctatcgtgta ttgcgagaaa
     2761 aaaatatgca acatcaccgt ggccgaagtc aagtttcaca aaaacgcata ccgccaagtc
     2821 accttgcgac gaagccaaat gaagtttgga cttgggatat tacttggcta aaaggtccaa
     2881 taaaaggact cttttaccgg ttatatctca tcattgattt atttagccgt aaaatggtag
     2941 gctgggagat ttgggaatca gaagaagctc gtcatgccga aaaacttatt aaacagacgg
     3001 tgcttaagga acgtatccaa ggacagccgt tggttttaca ctccgataat ggcagcccta
     3061 tgaaagccgc gacttttcaa gtcttactcg aaaaattagg aattcaaagt tcttattcaa
     3121 gaccacgagt gagtaatgac aatccttatt cggaagcggc tttccgaacg ttaaaatatc
     3181 gaccagaata tcccaataac ggctttaaaa caatagatga tgctcgaaaa tggacgaaag
     3241 agtttgtcga ttggtataac gattctcatt tgcatagtgg gattcaattt gtgtctcctg
     3301 cagcgtgtca tgaaggacga catctcgcta ttttagagaa acgaaagcag gtttacgagg
     3361 acgctaaaaa gcgccatcct gaacgctggt caaaaggtgt tcgaaattgg actccacatc
     3421 aatcggtggc gttgaatcct ttaaaagaaa cagaaagtta acaggagcat aatctttcaa
     3481 gattatcaaa taaccctcgt cacccaatag gggaaaaagt tattcttccc ctattggata
     3541 acgaggccaa ccgaccatag ggaggttctg ctttttgata ggtggaaaat aaaaatacga
     3601 caactatatt gacaaacacc gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa
     3661 gtttacgcac tgcctctaca acgattaaag gcatggaagc catccgagga ttatataaga
     3721 aaacccgaaa agaaggcact ctcttcgggt tttcggtctg tactgaaatc aaggtattat
     3781 tgggaatccc agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt
     3841 gcaacagaac cgaatcatta aaaaaacatt atacagagcc ttgggaagat gaagttttta
     3901 gagtaattat tgaatataac aatgttccta ttggatatgg acaaatatat aaaatgtatg
     3961 atgagttata tactgattat cattatccaa aaactgatga gatagtctat ggtatggatc
     4021 aatttatagg agagccaaat tattggagta aaggaattgg tacaagatat attaaattga
     4081 tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt tattttagac cctcataaaa
     4141 ataatccaag agcaataagg gcataccaaa aatctggttt tagaattatt gaagatttgc
     4201 cagaacatga attacacgag ggcaaaaaag aagattgtta tttaatggaa tatagatatg
     4261 atgataatgc cacaaatgtt aaggcaatga aatatttaat tgagcattac tttgataatt
     4321 tcaaagtaga tagtattgaa ataatcggta gtggttatga tagtgtggca tatttagtta
     4381 ataatgaata catttttaaa acaaaattta gtactaataa gaaaaaaggt tatgcaaaag
     4441 aaaaagcaat atataatttt ttaaatacaa atttagaaac taatgtaaaa attcctaata
     4501 ttgaatattc gtatattagt gatgaattat ctatactagg ttataaagaa attaaaggaa
     4561 cttttttaac accagaaatt tattctacta tgtcagaaga agaacaaaat ttgttaaaac
     4621 gagatattgc cagtttttta agacaaatgc acggtttaga ttatacagat attagtgaat
     4681 gtactattga taataaacaa aatgtattag aagagtatat attgttgcgt gaaactattt
     4741 ataatgattt aactgatata gaaaaagatt atatagaaag ttttatggaa agactaaatg
     4801 caacaacagt ttttgagggt aaaaagtgtt tatgccataa tgattttagt tgtaatcatc
     4861 tattgttaga tggcaataat agattaactg gaataattga ttttggagat tctggaatta
     4921 tagatgaata ttgtgatttt atatacttac ttgaagatag tgaagaagaa ataggaacaa
     4981 attttggaga agatatatta agaatgtatg gaaatataga tattgagaaa gcaaaagaat
     5041 atcaagatat agttgaagaa tattatccta ttgaaactat tgtttatgga attaaaaata
     5101 ttaaacagga atttatcgaa aatggtagaa aagaaattta taaaaggact tataaagatt
     5161 gattatataa tatatgaaaa gctattataa aa
//
LOCUS       DARBDN010000136         5107 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000136 DARBDN010000000
VERSION     DARBDN010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.140"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..272
                     /locus_tag="SCH06_002629"
     CDS             <1..272
                     /locus_tag="SCH06_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1079149.1"
                     /translation="QMKAYRNKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHG
                     KVYNCFEELKSAIDSYIYYYNNERIKQKLNWQSPVQFRKTTVTVV"
     gene            complement(442..1404)
                     /locus_tag="SCH06_002630"
     CDS             complement(442..1404)
                     /locus_tag="SCH06_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEG1079150.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1406..2845)
                     /locus_tag="SCH06_002631"
     CDS             complement(1406..2845)
                     /locus_tag="SCH06_002631"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEG1079151.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3030..4976
                     /locus_tag="SCH06_002632"
     CDS             3030..4976
                     /locus_tag="SCH06_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEG1079152.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1656 a          859 c          835 g         1757 t
ORIGIN      
        1 atcaaatgaa agcttataga aacaaattga aggagtacaa aatctttcaa agcatgtctc
       61 ggaaagggaa ctgcttagat aattcactta tggagaattt ttttggctta ttaaaacaag
      121 agatttttca cgggaaagtt tataactgtt tcgaggaatt aaaatcagcc atcgatagct
      181 atatctatta ctacaataat gaacggataa aacagaaatt aaactggcaa agtcccgtcc
      241 aatttcgtaa aacaaccgta acagttgtgt aaaaatatca ttttagagca tgaaaaaagg
      301 agtggatttc tccactccaa aaaagtctaa cttttggggg tcactacaag ttgacaactc
      361 ctttttgttt acaaatcaat tggatatcta caaattgtat tttctaacga attttataga
      421 cattaaaaaa ttaatttaac gttaaatact tcctccagaa agtattgaga ttggtaaaat
      481 ataatcctta tttgtctttt cgcctttaat ttttttcaga agaatatcaa caataagact
      541 tgcaatttca tcaattggtt gtcttattgt tgtcaattgt gggaaaaatt tctcaataaa
      601 agaggtacca tcgtatccaa taatttttaa atcttctggg atattaagtt taagttgatg
      661 agcaattttc atagtgagaa tggctgttaa atcatcagaa acaaaaatac catctggttt
      721 gtgatttata atagttgact ttatttccat ttcacgacgg atagtagaca gattattagg
      781 aattttgaaa atttttccat ttggattttg aaaagaaaaa cctagtgcac gtaattctgt
      841 gggagaatcc gtgttatcat ttcctgtaat cataatggta ttttgacaac catttttttg
      901 taaagtctta gctgcaagtt ttcccccttc aaagttatct gaagaaacaa tggaaacatt
      961 aggagctaaa tttctatcaa aagcaacaat aggtgctctc acacgctcat aatcagcaat
     1021 tccaagatta tggcttgatg agattatgcc atcaacttgg ttggcttcaa gcatttcaat
     1081 gtattctctc tctttagcag gatcattttg actattgcaa ataatcgttt tatatccatg
     1141 tttaaataac tctatttcga gatactcaat gagttcagag taaaagatat tactaatatt
     1201 aggaaaaata agaccaataa gctgaggtga ctttccttga agtccacgtg ctaaattatt
     1261 tggtttataa ccaagagttt tcatagcttc atgaactttt tgttttgttt tttctgataa
     1321 atatccctta ttattaatga cgcgtgaaac ggttgttggg ctaactccag ctaattcagc
     1381 gacatcagtt aattttgcta ccattttaat attttaattc aaagtatttt ccagtaggtt
     1441 cgcctgattt gatttgaata ccattttggt gattttcagg gaatacacga ctagtaaaca
     1501 ctttttctcc tttattaata aaaatctcaa tgattgagtt atctacaaaa atgttagcag
     1561 ttgtttcttt agtatcaatt gagcattcac gaatcgtacc aaagtcagtg gcatattgaa
     1621 tgcctgcttt gctgcgatct aaaataattt ttccttcttt ggtatctaca atcaagctaa
     1681 gtccatttcc tttactatca gagaaaagaa gtaactccga tttctgattt ggaggaaaag
     1741 ttagttcaag ctcataagta ttatttgttt ctgcttttgc tgtaaattgt tcagaactag
     1801 cacgtaatga tgtaatagct tctactggat attggtaaag tttaccatct tttattgaaa
     1861 gttcttttac aagactcatt gctccctgat aatcatactt atcagttgga taatcgatat
     1921 caggtagtcc aatccaactg acaatcagag cacgaccatc aggagtattg aatccttgag
     1981 tcgcatacgc ttcaaatcca taatcaagat tttgaatttc tgaagcgccc acaagtttta
     2041 ctttttctat gtcaagcgat tgacagatct taaaagtatt cggatagata ttcccataat
     2101 ttagctcaga tttatccaac ccttgaggac aataaatgag aacaggtttt ttgtctacaa
     2161 atactagatt tggacactca atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc
     2221 caacttcctc ccatgtttcc acgttattgt catccgcttt gtaaagtttg ataaagcctg
     2281 atttttctaa attttgtgct ccaacaatcg catacaattg tccttcataa ttaaacattt
     2341 gtggatcacg aaaatgatca gttacatcag caggtttatg aataagaaca ttctcacctt
     2401 tcgtaatgtt gtagtcttta tccatccatg ctccgatttg aagtgtatca cgttcccaat
     2461 tttcatttcg aacgtttcct gtatagagta agaatagatt cccctctatt tcatatgcag
     2521 aaccggaata agcgccgtgg ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta
     2581 catgaaaatg aactaaatca tctgattcat tgtgtaccca ttctttcaac ccatgagcag
     2641 ctccaaatgg ccaattttga taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat
     2701 taggatcgtt taacaatcct gttttaggtt cgatatgata gctagcacgc caaggtgatc
     2761 gttttacatt atccttaatt ttatccatct catctttagt ccaatcagaa taagcacgat
     2821 atcgtatttc tcgaggtaag ttcatatttt actccttcaa tttatctttt tacaactagt
     2881 atggtaaacg ttttccgttg aaaaatcaat catttcattt aaaaaaataa actatatgac
     2941 aaacgtttga catattttta agatatgcta aaataaattt gcatttcagt gaaccgtttt
     3001 cacgtaaaaa taaaaaagga gtgattcgaa tgaattacag taaagtagct tccgacgtaa
     3061 tacaagcggt cggaaaagat aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc
     3121 tcgtactaaa agatgacacg aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga
     3181 aaagcacatt taaaattaat ggacaatatc aagtgattat cggtgcaggt gatgttaatt
     3241 tcgtttatga cgaacttatc aaaaaaactg gactttcgga aatttcaaca gatgatttaa
     3301 aacaaattgc tagtaaagat aaaaaattca accccattat ggcattaatt aaattattat
     3361 cagatatttt tgttccaatt atacctgccc ttgttgcagg tggtttatta atggcattac
     3421 aaaacttttt aacagctgct ggactttttg gaccaaaatc aattgaagaa atgtatcctg
     3481 cgattgaagg tatttcctca atgatccaac tgatgtccgc tgcaccattc atgttcttac
     3541 caattttagt aggtatttca gctgctaaac gttttggagc aaaccaattt cttggtgctg
     3601 caattggtat gatcatgaca acaccagatc ttggtggctc aactgaatat tggaatattt
     3661 ttggttatca tgtttcacaa acaaactatg cttatcaagt tattccagtt ttagcagctg
     3721 tttggatatt atctatatta gaaaaattct ttcataaaaa attgccatca tctattgact
     3781 ttacattcac gccattatta tcagtaatga ttactggatt tttgactttc acagttattg
     3841 gccctgtaat gttattgttg tctaatggaa ttacagacat tattgtttgg ctatataaca
     3901 ctactggatt tattggaatg ggtatttttg gaggaacata ttcacttata gtcatgactg
     3961 gtttacatca atcatttcca gctattgaaa ctcaattact ttcagcgtgg acaaatggta
     4021 tcggacatgg agactttatc tttgtagttg catctatggc aaacgttgct caaggtgctg
     4081 caacatttgc catttggttc ttaactaaaa attctaagac aaaaagtctt gcttcctctg
     4141 cgggtgtctc agcacttctt ggaattacag agcctgcctt gttcggagtt aacttaaaat
     4201 accgctttcc attcttttgt gctttaattg gttcaggaat tgctacagca gtagcaggat
     4261 tacttaaagt agttgctgtt tcacttggtt cagcaggttt cttgggattt ctttcaatta
     4321 atgcaacatc tattccattt tacgtattgt gtgaattgat tagctttgta gttgcttttg
     4381 caattactta cttctacggt aaaacaaaag ctgctggtat ctttaaagca gaagaaattg
     4441 ctgaacaaac accagttaat tcttcaaaag tagcaacaac agatccaata tctactgatg
     4501 ttgaatcaac acaaacaaaa gtttcatcag aaacaattgt tagtcccatt tctggtaaag
     4561 tgattagtct ttcttcagta aatgatccag tcttttcatc agaagctatg ggaaaaggga
     4621 ttgccattaa accaaatgga aacacggtcc attctccagt agatggtact attcaactca
     4681 cgtttgaaac tggacatgct tatggtatta aatcaaataa tggtgctgaa gttctaattc
     4741 atattggtat tgatactgta tcaatgggag gaaaaggatt tacacaaaaa gttactacta
     4801 atcaaaaagt tagaaaaggc gatattcttg gagcatttga ccgttcaatg attgagaaag
     4861 aaggtcttga tgatacaaca atgattattg tgaccaatac ttcggattat tcagaagtaa
     4921 atatagtagc tgaaaataca gtcactgagg gtactgattt acttgaaatc aaataaatat
     4981 atttccctga gtaaagatgg aattttcttt ccaaaatcaa ataatataga ttaatcaaat
     5041 atttgagaat aacattttat ttaatctttt catatatcaa ttgtatgaaa aattattaga
     5101 attttaa
//
LOCUS       DARBDN010000137         5066 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000137 DARBDN010000000
VERSION     DARBDN010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.141"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..254)
                     /locus_tag="SCH06_002633"
     CDS             complement(<1..254)
                     /locus_tag="SCH06_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079153.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
     gene            complement(244..1443)
                     /locus_tag="SCH06_002634"
     CDS             complement(244..1443)
                     /locus_tag="SCH06_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEG1079154.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVGGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1573..2949)
                     /locus_tag="SCH06_002635"
     CDS             complement(1573..2949)
                     /locus_tag="SCH06_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1079155.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2949..3605)
                     /locus_tag="SCH06_002636"
     CDS             complement(2949..3605)
                     /locus_tag="SCH06_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEG1079156.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3615..4892)
                     /locus_tag="SCH06_002637"
     CDS             complement(3615..4892)
                     /locus_tag="SCH06_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEG1079157.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4911..>5066)
                     /locus_tag="SCH06_002638"
     CDS             complement(4911..>5066)
                     /locus_tag="SCH06_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HEG1079158.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
BASE COUNT         1591 a          925 c          628 g         1922 t
ORIGIN      
        1 gtatcgactt ccttaatggt ttgtcgcatg gaacggatac cgaataaata ctgaataaac
       61 accaatttga tcagaatcac tggatcgata cttgggcgac ctaaatcgga gtaagtggct
      121 tcgacgattg gataaataaa ttcaaaatca agcgcggcat caatctttcg aacgagatga
      181 tcttgaggaa ctagatcatc aatcgtaagc atcgcaaatt gatttctacc attcgtattg
      241 tttttagaca tcatagctat cactccttgc attcgttttc ataaatctat tataaaagaa
      301 aagactgtag acatcatcca taaaatggac tttgtctaca gtctgcgcat tctcattaga
      361 gaacactccc ttttttgtga cttttctgaa gctagagtga atactttcaa ctgcattagt
      421 agtgtacatg atttttctaa tggcgctgcc ataatcaaag agttgttcaa catgagaaaa
      481 gtttcgtttg catacatcta ctgcaccaga ataatgagac caccgatttt gaaaactgtc
      541 gaaggcagcg tgtgcagcgt ttaaagaaga agcactgtag aattttttca tgtctcgaca
      601 gacttcctta taatccttac ttgggaggta tcgtaacgca tttcgaacaa gatgaacaat
      661 acagcgctgc acaatgacag aaggaaaaat tgcttttgcg ccttctttga gaccggaaac
      721 accgtccatc gaaatgaaaa aaacatcttc tacaccacct actttcagtt catcaaatac
      781 ttgcatccag cgatttttag attctgtttg attgagccat aggcctaaaa tctccttgtt
      841 tcctttaaga tcatagccaa gaatggtgta cacagcatat tctttagctt catagttttc
      901 gcgtaaagtg acgtacatac aatcaacgaa tagaaatgca taacacttgg ctaatggccg
      961 agcttgccat tcttccaatt caggaaggac ggcatccgtg atatcagaaa tcatttcgtg
     1021 ggaaatatca aagccgtaaa tatcttcaac ggttgcggcg atatcgcatt gactcattcc
     1081 tcgtgcatac atggaaagaa ccttaccttc gatgtcggag acatctcgtt ttctattagg
     1141 aatcaactca ggttcaaaag aagcctcccg gtctctggga acatcaatgt ttactttacc
     1201 aaagctcgtt ttaagcgtct tattgccata accgtttcgt cgattgtcat gtttctttgg
     1261 ctctttagaa tgggcgtcat accctaaatg gttattcaat tctccttgaa gcattttttc
     1321 aaataaggga ccaaacacat cttttaaaac atcttgcata tcctctacag attcgggttg
     1381 ataagtattc aaaatggatt cagctaactt ctcagcatca ggatttcttt tctttctagc
     1441 catcgtgtaa tcacctcttg atcttatttt agaaaaataa aaaccgtgaa gcaaccaccc
     1501 gcctaggatt gatggttact tacacggttt atattacact ctcatttttg gtgctaaaaa
     1561 gcaccgaaaa ttttaattat tgtcaattaa taattctttt ggattccttc ttaatatatt
     1621 gaatgaagaa ataatcaatg atacaagaag tactaaactc ataaatataa ctacataaat
     1681 catgaattta ggtaatacat tgatatctaa acttgataat gtcttgttaa atccttcagc
     1741 ttctgcccca ccacctaatt ggctagatgc agattgttta gctatttgtt tagctatatc
     1801 accagtaacc ttattcaata tattattccc aagcttgtca gctgtatatt gagctaagaa
     1861 ataggaacca acgaatgcgg ggattgatat aaataccatc tcaattagga attgaccaaa
     1921 aatttctaat tttgatatac ctaatgatag taatactgct atttctttct ttctagcatt
     1981 catccataag aataataata atgaaactac aactcctgca aatattaatg agccaaaaaa
     2041 taatttattt gaaattgagt aaatacctga tatagattgt tgtaatgcag ggtaatttga
     2101 tgaactttta atcaaattat attctctcca atttatatct aatttcccaa gatcttttat
     2161 tacactatca agattcttat caccttttac aaagaatgtt gcatcttggt atacagctgt
     2221 atcttcggta ttaccataaa ctttagcagc tgtatgaata tcagtgatta atgtattttc
     2281 gtatagttct tgtgctgcac ttactccacc gctattatgc ccatcgaata gacctttaat
     2341 ttctacttct actgtttcat ctgcaccttt ctcattatca gcatcaaata aattagattt
     2401 tatttttatc ttatctccaa ctttaaggtt atttttttca gctaaatctt tatgcattaa
     2461 gattttattt ttatcttcat tttctaaatg ctttccttct actaatttat atgcttctga
     2521 tacaaatttt gtttcttttg ttgagtcgtt aaccccagtt aacataactg ttcttttaaa
     2581 attctttgct ctttcaggtg attgattcgc aagagtctct tgagtttcaa taatatcata
     2641 atcaactaaa tctgcaacac tgtttattct ttttacatag gagtctatac tatctgtttg
     2701 agatatcttt ttaatatctt caccttttac atttccccca cctctaggtg ttcctggatt
     2761 tacttgtcta tttatctcca tagaaaaact atttgttata ttagcaaatg tttcttttga
     2821 agctctgtcc gtagcatctt taatagataa actaatgaga cttaaagttg acatagataa
     2881 aataactaat atgataatta atgattttaa actttttcta gttacataag caaatgcatt
     2941 ttttatcatt attcaacctc caaattcatt ttatttactt ttttcaactt tttaccactt
     3001 agttctaaaa tgatatccgc agaatctgct acttccttac tatgtgttac aactattaca
     3061 catttatttc tatctttagc taatgtcttt aatatattaa ttatttctcc agcagtaaca
     3121 ctgtctagat taccagtagg ctcatcagct agtattattg gagcatctga taccaatgct
     3181 ctagcaatag ctactctttg ttgctgtcca ccagataatt tcataacatt tctttttatt
     3241 tgttttttat ctaaacctag ttcaaacaag atactttcat ctgctgattt atttactaat
     3301 ctaatatttt caattggtga taaataatct attaaattat agttttgaaa tactaaagat
     3361 atattatttt ttctatgatt actatatcct ttattttgta tatcttcatt cttaaacaat
     3421 atttttcctg tttgaggttt atcaagtcca gcaagtaagg aaagaagtgt agattttcct
     3481 gttcctgact ttcctactat cgcataaaac ttcccaagtt caaatttttg atttactcct
     3541 gacaaaactt tttctttaga atttgcataa ctatatgcta cattctttat ttctaatata
     3601 tccattattt tctcctaact tatttttgat aagatttctt taggcttctt gattaacatt
     3661 aatgaagaag caaatacaac tgataaaaca ataatactta ttaatattaa ataactttgt
     3721 ccaagtgttg ttatatttga cataaaacta ctattattta ttaaacttcc accggaaatc
     3781 attgaatcct ctgagttaat gaatccatct acaattactt ttagtaatac atttcctaaa
     3841 aataaggaag atattatact tggtatcgat atgaatatta actcgaatat aaattgcatt
     3901 ataatttgta tcttagatgt tccaatagat aagaatatac ctatttcata aattctttcc
     3961 cttaaccata gaatcaagat taatgaaaga acaaccatcc cacctaacat aatagaataa
     4021 gtcattactt ttattatata ttttattcca ctcactgact ctaaagactc ttcaaacgca
     4081 ttagaatctt tttcaacaaa atactttgac tcatcaattt taagctcttt caatttgttt
     4141 aaggctaagt ctgtagattc tgcactacca gaatacatta aaattttatt tgcaatttca
     4201 ttattttctg aattatttaa tatctcttgg cttgttgaat aatctacaaa caccatattt
     4261 tcactaaaat cagaagataa tcctgtatat gtttcctgtt ttttaccaga aaagatccct
     4321 ataattttaa atttatgact ttttattttt ccactttttt caatatctag taattcaaga
     4381 tcaacttcat cacctaattt tagattgttt tgtttagcaa attcttcatg aacaataatt
     4441 gaattcttat cattttcttc tatattttta ccttctttaa ttgtaaatac tccactacta
     4501 aataaaatat ttcttttagt attatttgta gcttcgagtg aaacaacatt cttaaattcg
     4561 tcagataaat cttctctatt tattctttgt tctccgctaa ctactttagc atcttttagt
     4621 tttgctaatc catcatattg aattattttt tcttcaattt cttttaattt ttcaatatct
     4681 ttaaattgat taacattaaa atatttacca tctttttttg ttattgatat tgaagaatta
     4741 gaactttcat ataaagcctt ttctatttca ttgcttgatt tcattattgt taaacaagaa
     4801 tacaagcaag aaagaactat agttaatatg ataaaaatta ttaaagttct atttttcttt
     4861 cttgtaatat atgctatagc attttttatc actttcctaa ctactcctct ctattttctt
     4921 actccataac taattgcatc cactggacaa gcatttttac atcgtccaca tctgatacac
     4981 tccagatgat tgcaattctc aactgaatct ttattcattt ggcaaacttt tttacatttt
     5041 ccacaattaa tacacttatc cttatc
//
LOCUS       DARBDN010000138         5038 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000138 DARBDN010000000
VERSION     DARBDN010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.142"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            413..619
                     /locus_tag="SCH06_002639"
     CDS             413..619
                     /locus_tag="SCH06_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HEG1079159.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(821..1822)
                     /locus_tag="SCH06_002640"
     CDS             complement(821..1822)
                     /locus_tag="SCH06_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEG1079160.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1827..3740)
                     /locus_tag="SCH06_002641"
     CDS             complement(1827..3740)
                     /locus_tag="SCH06_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEG1079161.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3908..4414)
                     /locus_tag="SCH06_002642"
     CDS             complement(3908..4414)
                     /locus_tag="SCH06_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEG1079162.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4574..5014
                     /locus_tag="SCH06_002643"
     CDS             4574..5014
                     /locus_tag="SCH06_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEG1079163.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
BASE COUNT         1391 a         1007 c          769 g         1871 t
ORIGIN      
        1 tatttttgtt tcttattttc taaaaaatta aaaaaaattt tggtgaatta agtatttcct
       61 tgataacact ggcttttggc ctcattttag gttatcattt gtaattttat ttcacagttg
      121 atatgattgt tatgtaaaat aaaaaagttt aggatacatc gaatttttgg ggaaattctt
      181 ttgggggtat cctaaatctt ttctattata ttcccatatt ttctattatt ggtctagacg
      241 tatgatggta aactttgtac ctatctgatt gctgaatcat taattgctta tcattagcca
      301 tctttgtttc aagttcgcta gatgatcatt ttattcacat cctaacaaac ttgtcacatt
      361 tatagattct taatctattt atcatacaat tataaaaaag gaggtgctgc ttatgaaagc
      421 tatccatatt tctttgcttt ttttcgctag tgcattgatt ttatttgcta ttcatctttg
      481 ttcccagcct tatatcaata acaacggaat attagtggaa ccagcattct tttgcttacc
      541 actcggcttt ttgtcccttc ttgcctccgc aggcttcgga tttgttgctt tttttaaacg
      601 atcaaaacaa caaatctgac ttataaaatt tacgtaaaag agatcgtgac aataatcgtg
      661 tgatattccc aaatttcgaa taaaaggtgc cccttgccat ctctaactcc tcagtcacaa
      721 gttacaatat tcataaacca tgaaaagctt gtttattgaa attgctcctt gtgacttgga
      781 gctaagtgac agattacaac ctcttttgca tcataagact ttactccttg aaaaacatta
      841 ctaacttttg atatgtttct tgcgcttgtt tattgctgaa atcaaactga tattcatggt
      901 tcaaaacagc atttttctcc gcataatcta cttttgtgac tttcaccccc gctttctcaa
      961 atacagaagt tacttcttcc atttgtttcg taaacgtatt tgtatttcca tccgttaaga
     1021 atgtgttttg cgtccaacga tccgcatgtc tgaccaaggc taaacttttg accttctctg
     1081 attgttcaaa gtccttatta tcaaagtaag cccatccaca tttttcataa agaaagctag
     1141 agattttatc acttacttga gtaagtgcag aaggatccaa cagaccagac aaagaaataa
     1201 acttcgtaat ctgcttgttc tccaaagtcg gatcaagatg atcagctttt ttaatttctt
     1261 cattttgaag tgctaacaaa tattctccac taatttgtgc acctgccgaa tttccaccaa
     1321 tcgaaatatt cgaccaatct gcttgatctt ttatctcttt tttagctgct tgaatggctt
     1381 cgttcaattg gataactggt gtaggatgtt ttgcttccgg tgatcgttca taatctatat
     1441 ttacgatgat ttgctgcgtg tctgaacata gatattccaa ataatcacga caatcatttt
     1501 tatcccctcc tacatatgcg cctccatgca tccagaaaag aatcggtaat tttttctttt
     1561 ccactttcgg tgtgtagata tccatattat tatttttgta ctttgaagga taggatattt
     1621 ctttttttat atcgatttgt tcgatttttt gctggaaatc atctggtcgg gcatatactt
     1681 gttctttttc acttgtgtca aattgttttc taacaagcaa gctaatcggc tttggtgtga
     1741 tttgattaat caaaaataca gtgactaaaa taactacgat gataactggt actgcaatca
     1801 ctattcgctt gaaccatttc attcatttac cctctctttc ttcgccaaat ccatgtgata
     1861 atcgtgctaa cagataaaaa tccacctgaa taaatgagaa gcgaatgttt cttttctcca
     1921 gttttcggca acattctttt ttttgcatct gtcttttttt gtactttcac tgtcatctga
     1981 atcggttgcg tatcatcact tgattgatcc tctcgaggtt cattctttcc cttattgtct
     2041 gcattctctg tcggatcttg cttttttggt ggagctactg ggattttttt gtaatagaaa
     2101 ataatagttg gtatcgtctc attaaaaatc ccttcagtcg gtccttcaac atttgctaat
     2161 tcgtatcctt cgaatgtctt ttgctctgtc atataatttt ctccataagc tccgtaaagc
     2221 tggatttcgt cctggtcttt gagtagactt ttattgtttt catccacata ctttacgttt
     2281 atctgatcat ggaacactac tttcaaaaag tccgttacat gtttcgtgta ggcagcatgg
     2341 tcaacttcct gtgcctttcc atgccctgct ccttctacta ataaaagatc tttataccct
     2401 cctgataact catataattt ttgcgcgtta gacacaggta ctacatcatc tgctgttcca
     2461 tggataatca atttaggcaa tgaatctgac attccaatcg taggtagagc agcttttgta
     2521 tccaaatgca tctcctgatc aaaatagtat tgtttcaaaa ggcccataaa taaatcttca
     2581 tgctcttgat ccccaatgat gtctaactga ttttttatgg catccggtag tgcgggggct
     2641 actgtctggc tgtacgtaaa acgtagttgt tcatcaattg atgcaaatcc gcaattttca
     2701 ataattcctt tgacattgac aggaatatct ttcgctaata cagacatcat cgtagctgct
     2761 cccatcgaac caccataaag taaaatcttt tgagatggcc gctctcgaac ttcttgattt
     2821 atccagtaaa ggacgtcatc tgactcatat tgtccatagg tcacataatc gcctccgcta
     2881 ttaccagtcg ctctggaatc aacaaataat aaattatacc cggccttata aaaatcattg
     2941 tattcttctg taacgatccc gttattccaa ttccctcgaa atccgccatg gatcatgact
     3001 gttttatctg aaccttgatc gacataatat gcatatacat ccatcatttt gccatcttgt
     3061 ttgtttagta cagtttgatg aagttgtttt gtatttggat agaagcctgt gttttctgta
     3121 ggcgttgtcc catcatctgt acctccaagc atcgacatca acacactgtt ttttgcaaaa
     3181 gcgatatcgt acaatagata agtagcaatc agatgtttga taatctcttt atctacacca
     3241 taatcattaa cagcaagctc agtgactaat aactctatta attttgactt gatgtcttct
     3301 gttggtccat taagtatttc tgtcatctgt ttaccgaagt aattcaaata ttctttacca
     3361 ttgaaatttt cacctttacc gatatcatca ttttctgtcc cattctcttt gtcacttact
     3421 ttagcagaag aggattcgtc gtttgacatt tttgtagctg ttgcttcttc tgtttgttgg
     3481 ttatctgtgg tagcggtcgt ttcttgatct gtgctagtaa cagatgtctc aaccgttgtt
     3541 tcagtatttg tttctgtttg tgaagtactc gatttcgttt catttccagc atcagtagtt
     3601 tctgtggttt ctacctcccg agattccgat tcggaagaaa tgctctctcc atatactgtc
     3661 cattgcggga cgcttgtact tacagcaaat aagatgacca acgctccctt taatacttgt
     3721 tttgttctca agctattcac tcctttttat gtttctagga gaattatatg taaacgcaaa
     3781 cattttttat acaaaaaata aatggtttat cccataaaaa tagaacagga ttattttctc
     3841 attttacgta ataaagcaga atggataaac cagtatccat tctgcttttt ttaaacgaag
     3901 aaacaactta ttgctccaaa aatgtcagaa atcgtttatc ccaaattttc tcgtaaaaag
     3961 cgattgtttc ctttgctttc ataaaaggat tatcataagt tgtcgttgct cctctacaca
     4021 tcataagctg gtatcctaat ccatgagcaa acttcacagt cgtatctata caatactctg
     4081 cttgtgcccc acataattcg atcgaatgac agtccaattc agttaataaa acactcaaat
     4141 tagtcttata aaatgaattc gcatgggttt ttctcacaaa ataactgtgc tcaggaatag
     4201 ataattccga caatagctcc catggttttg tttgtggcac taattgagca tcttcgtgtt
     4261 gaacgaaaat aactggtttc ccaatcgttt cgtatgtttt gattctttta ttcactaatg
     4321 ctgtcactgt ttctaattcg tgtatcggcg aagaatcaaa acatacccct ttttgtaaat
     4381 cgatcactac tattgcgtcg gctgtgtttg acatacttgt gccttctttc ttttttcttg
     4441 atttaatagt atttcttatc tagctagttc cattatacgt gacaacattt tcttatttta
     4501 cacctctaaa tggcactttt cgactatttc ttcatgttat tatttcataa atacttagct
     4561 attggaggaa tgtatgatga ttaaattgta tacaggttct ggctgctcgt cttcaagacg
     4621 cgcaaaacgt tggcttatcg tccatgatat accgtttatc gaacagaact taattcgtca
     4681 accactaacc aaaaatgaat ttatccactt actaaaattg acaaacaacg gcgtgaccga
     4741 aatgctctct actcattcta ttagttataa aaatcttgtt cacagaatag atgaactcag
     4801 tttgagtgaa ctatatattg agattcgtac atccccttct ttattgaaaa aaccgattat
     4861 ctacgaccaa tctgcaaaac ttttgactgg atttagcgaa gataaaatca ggatgttcct
     4921 ttctaaaact aaaagaaagc aagagctcaa cgaactcttg ctttctggtc atcttgtcga
     4981 ttttaaagaa aataatcttt ttgcaatgtc ttaattttgg cataaacaat ctgctttt
//
LOCUS       DARBDN010000139         5035 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000139 DARBDN010000000
VERSION     DARBDN010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.143"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(6..1163)
                     /locus_tag="SCH06_002644"
     CDS             complement(6..1163)
                     /locus_tag="SCH06_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079164.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(1166..1522)
                     /locus_tag="SCH06_002645"
     CDS             complement(1166..1522)
                     /locus_tag="SCH06_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079165.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(1820..2794)
                     /gene="sgrA"
                     /locus_tag="SCH06_002646"
     CDS             complement(1820..2794)
                     /gene="sgrA"
                     /locus_tag="SCH06_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HEG1079166.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(2990..3829)
                     /locus_tag="SCH06_002647"
     CDS             complement(2990..3829)
                     /locus_tag="SCH06_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEG1079167.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            4014..4901
                     /locus_tag="SCH06_002648"
     CDS             4014..4901
                     /locus_tag="SCH06_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEG1079168.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
BASE COUNT         1638 a          995 c          745 g         1657 t
ORIGIN      
        1 ttttcttaat taacgaaatc caatttttcc aatatggatc tatttttctc attcctgatt
       61 tttatgattt cagctttcag acgcgcccaa tcattttttg taggttgtcc attccagtaa
      121 aatatctgtg tattcgtttg atcatatgcc tttttgtcga taggataatc gctaatgaca
      181 atatcaggta actgatcagc ggatgcacta tattttattg ggcgttcagt catagataat
      241 atccttttct ttgcccataa ttcctgtgtt ttaccatact ttgattgaat atagaatatg
      301 acaggttgtt cgtgttttat aaaaatatcc ctgactaaca tacagtattg aaaaatcaac
      361 cgtctgttct tttcataata agtattaagc tctggaattc tgcgagctac cccactaaaa
      421 aactgttgca tgattggata catcactgga aatatatgct gaaaatctct gtcttctgct
      481 gattttccaa aagcatccac cttctttttt gtcccaaaaa cccttgaata caaatggatc
      541 attgccaaat tgacatatag ataatttttt tctgaagttg taaaacaaat cttgaagttt
      601 ttttcaaaat tttctacaat agacgattca atccagcccc aactttcttg tactttatct
      661 ggagtatcca acaaatcttc ttccaaatag gtgttcatta caccaaacat aaaataaagg
      721 taagcttgct ctgttggagt gatgtgattc atcgaccaga agtttgcttc aaaaaaaggc
      781 tctagtatgt aatgcgtaaa ctcttctttt gttatcaatg gatgcacaaa tttgttcatc
      841 tcttctggga catacgtaat cgagtggcct tgtttcattc gttgcaacga aattcttagt
      901 aggctgatcc atttctttct atctatacta cgcgtatatg gcgcatgttt cgcaaatttt
      961 tctaatagtt gacgtttatt ttttatactt gataatatat cagaatgatt ttcgtcgaat
     1021 gactgccaat acatcaagtg aaaaaagtat cggatacggt attcttctcc ttctatcgga
     1081 ttaccttttt tcaagctgca agataaatga tagtttttca aaatagtatt aagttctctt
     1141 aattttcttt gaatcgtacg caaacttata taattttttg actaagattt tctaaggatt
     1201 gataagtacc tttgtaaagt gaatccagta aaatataacc aatcgttccc tctaaaagta
     1261 tagaataaac tttactcagt aaaaactgag aagaaaactc gacttttatc atcttgtttt
     1321 ctgaaagaaa agataattta tattctggat acctttcgca aaacgattct gcttgttgaa
     1381 tcaccgaatt catcttagcc agggtgtagt ttagatctaa agcgatatcc ttcaccacat
     1441 ataatttctc gtctctttca taacaatagt tcaaaaattg atatacttgc ctttcattga
     1501 tatcaataaa ttcttcaaac aaagtacata ctccttttta tctattattt agacttattc
     1561 cgacagctac atgaataacg tacaaataga ttcgttactg atttttcaga gatactacca
     1621 tgcgcagtgt gcattgtcaa ttattcttgc tcttattttc catttgtgtt cctgttattt
     1681 cctgtttctc aaatatgtta gtaaacaaaa atagatctgg caaagctaca acttcgccag
     1741 gcaatacagc actctcgaat gaaatattca ctcaaaaatc tatcgtttta ttcaatttta
     1801 gatctgttgc ttttattctt tatttcactc gatggaagag agaacgaaaa tagcttgctc
     1861 ctacaatcaa aatgagtaac acacccatcc atgtaattag cttgttcaag gttctactac
     1921 cagtttctgg taaatcgctt tttctattat ctgtttcttt cgctttttct tgatgatcaa
     1981 ttccacgaga aacaaaatca ggctgtttta gcacactttt taggttgctc cctgcatttc
     2041 tcttttgttc cttagttggt atgataggta ccaaatcaag ttcattattt acttttcctg
     2101 tgctgctttc gctgctcgtg cttcctgtgc tactctcact actcatgctt cctgtgctac
     2161 tttcactact cgtactctcc gtactgcttt cgctgctcgt gcttcctgtg ctactttcac
     2221 tactcgtact ctccgtactg ctttcgctgc tcgtgttttc tgtgctactt tcactgctcg
     2281 tactctctgt actgctttca ccgctcgtgt tttctgtact gctttcacta cttgtgctat
     2341 ccgtactgct tggcggtcca acaactgtcc aactgcttgg tttcaaattc tccgtgatcg
     2401 tcatctgtcc atcataaaaa acaatcaaat caactttatc tttactcttg atctcatcaa
     2461 tcgatagttc tgcagaaatc attattgtat actcaatacc agcggtccat tgtacgtctt
     2521 ttaaataaac ttccccaata actttttctg aacttccatt accatcccaa ccatatgtta
     2581 gaacagcatg tacatcacta gcattcacgc ttttgtttgg tttgactgga atagtaatga
     2641 cttgttgtgt catgtcataa acaatccgat cagttttcac agtaaatgaa agattctcat
     2701 ttgcccgttc atttgcagaa gtactgattc caatcattgc tgcaattata ctcagcccaa
     2761 gaataacaaa taatacggtc gctgttttct tcatttctat cactctccat ataattacct
     2821 tctatttgat aaaggaatta tataaaatga aaatgatgag aacacgacag tcagttgtga
     2881 aaatctaaca aaagatgtcg tgtattcgct tgaatttgtt tactttttcg tttaatcaat
     2941 gacagactta aaaaagcaag accgatatca gccttgcttt cttcatcttt tattgataaa
     3001 cagcagtgta tttcttcatc cgctttgttt tatatgcata gagtaacaaa ccaacaatca
     3061 agactaacaa gaataatgta gttgatatag atgcttcagc cccaaagttt cccccagtaa
     3121 ttattgtatt ttgcgattgg atcagagtgg agaaaaaacc ttgttcttgc gttccgctga
     3181 ctggtatacc caaaatagct ccttgtgtcc aattccaagt aatatgagca ccaatagccg
     3241 taaataaact tcctgtactg tagataagtg cgctgaaaaa gcaacctgct aaaaagatat
     3301 tgaaaactgc cagaaatgtc atgttaggat tcaatccgtg caaaagagca aataatgcag
     3361 cagatccaat cattgctatt aacggaccaa atctaagcat ctgatgctga aaaaagccac
     3421 ggaataaaag ctcttctgat gcccccactg caataaataa aataaaactc gttatcagcg
     3481 gcacaatgtt tgcgtttcct gaatctaacc gatacgcccc cgtcaaatat aatggactag
     3541 taataagcag aaacactcca attccaacaa cgagacctcc cgctaaatac ccccagtctt
     3601 ttcctcgaac agaaacacca taatcttcta ttctttttcc ttcgacctta ctagcaagaa
     3661 ataaagctag taaaaaaaca gctaaatgtc cgaccgtacc ggcaattgct ccaatccatt
     3721 cactatttcc aataaacata tccgcaagtg cattattgac aagaattcct aaaacaaaac
     3781 caactaagac tattaaaaca gatccaatca accgaataat cctgatcatc tttcatccct
     3841 cctttatatt aagtttaaca acccttttct ttcttgtctc gtgaaaacta tgtaaatgtt
     3901 ctccatcata gagagaatag atttttacga actaagaata tctacagcaa ccttacgaaa
     3961 atgaaagact gtctccctaa ttcttctgtt agactgtttt taataaggaa aggatgggaa
     4021 attttttgaa aaaacaacta ctaattatgt gcctttcagc atgtgcaatt ttactattct
     4081 caggttgtag caagtccaat gaaacgattg caacgtttaa aggtggaaca cttacagttc
     4141 aggattttta tgataaccca aaagttaaat caaataatca aacactatta aaaaaaatga
     4201 ttgtcttcaa agcatttgat gatgtatacg gaaaagagat ttcttcaaag gaagtaacaa
     4261 aagaatataa tgaacaaatc aaaaaactcg gtccaaacta caaggaacaa ttaaaagcag
     4321 ttggccaaac agaagagaca tataagaaac tctttaaaca gatgctggct ttccaatacg
     4381 gtttgaaagc caatgtaaaa ttaacagata aagatctaga cactgcttgg aaagaattct
     4441 atccagaagt tagtacacag atcattctat tttcgactaa agaagaagca gataaagcaa
     4501 aaaaagaagc aaatgaaggg gaaaatttct ccaagcttgt tcaagcttat ggaaaaaata
     4561 aaacattaaa ggaaactgat ggaaaaatga attttgattc aaccaatcca gagattccta
     4621 ctgaagtaaa aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg
     4681 taacagatcc aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg
     4741 ataaaggttc taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa
     4801 aaactcttga tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg
     4861 taactattaa agatccttat gtaaaaaata tattcaaata aacaaatttg acccaattgg
     4921 ggatgtggca aaatttgaga agtgattttt ggaaattcct tcttattttt gaggcaaacc
     4981 acttttgcca caacttcatc ggggcctttt tttatttgta ccaaaacaaa tcact
//
LOCUS       DARBDN010000140         4805 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000140 DARBDN010000000
VERSION     DARBDN010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.144"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            72..1118
                     /locus_tag="SCH06_002649"
     CDS             72..1118
                     /locus_tag="SCH06_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEG1079169.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            1135..2358
                     /locus_tag="SCH06_002650"
     CDS             1135..2358
                     /locus_tag="SCH06_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEG1079170.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            2447..3334
                     /locus_tag="SCH06_002651"
     CDS             2447..3334
                     /locus_tag="SCH06_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEG1079171.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            3420..3650
                     /locus_tag="SCH06_002652"
     CDS             3420..3650
                     /locus_tag="SCH06_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEG1079172.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(3707..4672)
                     /locus_tag="SCH06_002653"
     CDS             complement(3707..4672)
                     /locus_tag="SCH06_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEG1079173.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
BASE COUNT         1626 a          795 c          975 g         1409 t
ORIGIN      
        1 aaaaataggg cttaagtttg agtgacagtt tgtaggctat gttatactat ataagtgaag
       61 ggggacgtaa ggtgaaggta ttattatatt ttgaaagtga aaagatgctt gcaaaatctg
      121 gaatcgggcg tgcgcttgat catcaaaaac gtgctctgac ggaagtcggt atctcttata
      181 cactagatga aaaagaagat tatgacatcc tgcacatcaa tacatacgga atcaatagtc
      241 ataatatggt caataaagcc agaagagaag gaaaaaaagt tgtctatcat gcgcattcta
      301 cagaggaaga tttccgaaat tcctttatcg gatcgaacca gctttctcct atcgtaaaaa
      361 aatatctggt aggattgtac caaaaagcgg actatctgat cacgccaaca ccttattcaa
      421 aacagttgtt ggaaagctat ggtatccgtg tgccgattca agctatttcc aatgggatcg
      481 acttagagaa atatcaccct gatccaatga aagaacaaaa gttcagagaa tatttcaaac
      541 tgtctccgga tcaaaaagta atcatttgtg tcggtttgtt tttcgaacgt aaaggaatca
      601 ttgatttcgt agaaattgct aagaagatgc ccgaatacac atttatttgg tttggtcatg
      661 ttcccatgta ctcgattcct cggaacatcc ggaaaattgt aaaagaagat catcctgaaa
      721 atgtcctgtt tcctggttac attcgtggag agatcataga aggtgcgtat tcaggtgcag
      781 atctattctt tttcccttct tatgaagaga cagaagggat cgttgtttta gaagctttag
      841 caagcaaaca aaacgtactt gttcgagata ttccagtgta taatggctgg ttagaagata
      901 gcaagaactg ctatatgggg aagacaaacg aagaatttat ccgactgatc caacagatta
      961 ccaatcaaga actaccgagt acgacacaag ccggttatca aacagcaaaa gagcgaagta
     1021 tcaataaaat cggtgaagaa cttaaaaatg tatacgaaag tgtactgaat gaaaaagtct
     1081 ctagcaaatt aaaaaaagta aatcaggtca aggactagtt tggaggcgaa aaacatgaaa
     1141 atcggctttt ttaccgatac ctactttccg caagtcagcg gagttgctac atcgatcaaa
     1201 acattaaaac aagaattaga aagacatggg catgaagtct atatttttac aacgaccgat
     1261 cctaatgcgg ataagttgga aaaagatgtg attcgaatgc caagtgtacc atttatttct
     1321 ttcaaggatc gaagagttgt tgttagaggc atgtggtatg cttatttggt tgccaaagaa
     1381 ctagaactag atcttattca tacccataca gaattcggag cagggatact tgggaagatg
     1441 gtagctaaga agttgaaaat acctctgatc catacttacc atacgatgta tgaagactac
     1501 cttcattata tcggtaaagg aaaagtgatc aggcaatccc atgtaaaata cttgtctaga
     1561 ttatttgcaa atcatacgac aggtgtagtt tgtccaagtg aacgtgttat tgatacatta
     1621 cgcagctatg gtgtaatagc accgcttcgc gtgattccta ctggtatcga cattgaaaaa
     1681 ttcaaacgtt ctgatatcac tcagcaggat atcagcaaat taagggagtc actaggtctt
     1741 caggaaaacc atttgatgat tctttcttta agcaggattt cttatgagaa aaatatccaa
     1801 gccttgatta atgggtttcc tcaggtcatc tccgcttatc ctaacgccag attagttatc
     1861 gtaggaaaag gaccttatgt agaagagtta gaggaattga tctcagaact gcagttagaa
     1921 gaatttgtgc agttcacagg agaagtggac aacaatgatg tagcacttta ttataaagcg
     1981 gcagattatt ttgtcagtgc ttctacttca gaaacacaag ggcttactta tacagaagcg
     2041 atggcagccg gaacaccttg tgtcgtggaa ggaaatgctt atttgaaccg attgttcgat
     2101 catccttcat tagggaaaac ttttgaaacc gacgaagact ttgcaccagc acttattgat
     2161 tatatttcca gtgaagttcc taaagatcca aaagttttag aagctaaact ttatgatatt
     2221 tcatctacac atttcggcga agctatgatc gaattttatc aagacatggt tgtttatcat
     2281 gaagaagaga tgcgaagaaa agaagaagaa gactcgattg aacgaatcaa aataaaatta
     2341 aattcattta aaagataaaa ttcaaacatt ttttatgaaa aaatccttgt ttctagcgta
     2401 tactagcata gaagcaagga tttttgattt ttaggaggtc gaaaaaatga aacttggttt
     2461 tatcggaaca ggcgtcatgg gaagtgctgt cgcacgccat ctactagaag caggacacga
     2521 agtagctgtc tataatcgga caaaagcaaa agctgatcct ttagtaacag aaggagctat
     2581 ctgggcagat acaccaaaag cggtagcaga acaaagtaat attctcttta caatggtagg
     2641 ttaccccaaa gatgtagaag aaatctacta tggacagtcg gggatttttt ctgcagatat
     2701 ctcaggacat attttagttg atttgactac aagtacacca agcctggcag aaaaaattgc
     2761 aaaaacagca aaagaaaaag gcgcagatgc gttagatgca ccggtatccg gtggtgactt
     2821 aggagcaaag aatggtacac tgacgatcat ggtcggtgga gaagaagccg tttatgatca
     2881 agtactgcct ttattcaaag aatttggtac gacatttaca ttgcatggtt ctgctgggaa
     2941 aggtcagcat acaaaaatgg ctaatcagat catgattgca ggtacgatga caggaatgac
     3001 ggaaatgctt gtctatgcac aaaaaaacgg acttgattta aagaaagtga ttgagacgct
     3061 ttcaggtgga agtgcagcta actggtcttt aagcaattat tctcctcgta ttttaaaaga
     3121 agattacaca cctggttttt ttgtcaaaca ttttatcaaa gatttaaaga ttgcattaga
     3181 agaagcagaa aaaatggatc ttgtattgcc agcaactacc caagcattga aactatatga
     3241 agagttggca gataaaggtt ttgagaatga cggaacccaa gctttgatca aactttggtg
     3301 gcctgaagga aaaataccag aaaaaaaatc ataaaaaacg agttttttta gagaaaatca
     3361 atgcaagtag gctatgcttt tgatacaata taacagaaat aagaaaagga ggacctccga
     3421 tgacacattc acaattagtc gcaatcataa aacgactgga ggctatggtc gagtcagcag
     3481 ataatgaact gcaagttcgc cgttttgaaa aagaaggcgt agagaagtgt acagtaactt
     3541 atgataaagc gaccgataca tttgaattaa ctgaaacaga tactcatcag caatacgaat
     3601 ttgataatat cgatatcgta gcgatggaaa tctatgactt aatccaataa attttaggat
     3661 aattgacatt tgaagttgaa gatgcctaaa agaagccgag aagcaactaa tttagttgct
     3721 tttcagcttc ttttttgttt aacagttcaa tttcaaactg ttctttttct aattttttgc
     3781 ggtaactgat caagatttgt acaggatcga tttcttcttt tgacaattga cgtttcaaag
     3841 ataaatgagc ttctttcttt tcataataga agtcaggaga aacgtcacca gaggtaatca
     3901 ttgtttctgc aagttgacca taacaaacga ggtagtgctt tttctgactc tcatctgctg
     3961 ctaatggcat gctgaaggtg agcgatggtg ttcttaaaaa ctgcttttgt tcctggatcc
     4021 gtctaataaa ataagtaact aattcgatat ctttttgaag cataccggct ttttcgaaat
     4081 tcaactgata gatgaaatgt tgttgtcttt ttttcaagta agtcagtagc tttttatttc
     4141 ggccttgaaa cagcccttgg agttcctttt ttttctgttc aaaagtcatt tcctgtaggt
     4201 caggaagctg gactcgcaaa gctaacaaac taatttcaga caaccaaggc atttgataag
     4261 tttcttccat tatacgcaaa atagacggca tttttttata gagacgaaaa ggcccgtatg
     4321 ttcgagccgt aggagtatct gttaatacaa atcccttatt ggtaatatgt acataattat
     4381 aattactgaa ataattcatt tgtcggttat aaaaaggacg gtaatgttgg atcaattgac
     4441 actcgagcaa taaagcatct aattccgtgt ctactacgac gaaatcaaaa tctgttatat
     4501 gatgaatcat acgtaatact ttttttgaat gctgtttatt ctgatgaaaa tagctgctta
     4561 ctctattttt gagccgtttt gctttaccaa catagatgac cttaccatct cggtctttca
     4621 taagatagac acccggcagc atggggagag ttttcatttt ttcttttaac ataggatctc
     4681 cttttacgct ttgaataaaa agactataac aaattttgaa ataatggaca agttttaggg
     4741 aattctatag ttctgttcac agaaaatact ttgataatca aaatatgtga gatagatgat
     4801 ttttc
//
LOCUS       DARBDN010000141         4788 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000141 DARBDN010000000
VERSION     DARBDN010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.145"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            564..989
                     /locus_tag="SCH06_002654"
     CDS             564..989
                     /locus_tag="SCH06_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079174.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            1019..1183
                     /locus_tag="SCH06_002655"
     CDS             1019..1183
                     /locus_tag="SCH06_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079175.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            2141..3118
                     /locus_tag="SCH06_002656"
     CDS             2141..3118
                     /locus_tag="SCH06_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEG1079176.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     YFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQIYSEKDPTSLQEKIKEQKRKLELL
                     QQLEELERKQNNLNKENKEINEQIPDNNSDIPPELKKGLLDNLQNLFKE"
     gene            3128..3625
                     /locus_tag="SCH06_002657"
     CDS             3128..3625
                     /locus_tag="SCH06_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079177.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            4001..4282
                     /locus_tag="SCH06_002658"
     CDS             4001..4282
                     /locus_tag="SCH06_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079178.1"
                     /translation="MDILVRNINPKIITRIDKRCQELTTKTGKKWSRNQYLKILIEND
                     FDHELMNYKKDQFDLLFEKFIAIQAENTNILNDYVHTNNQLIETLIGGI"
     gene            4284..4700
                     /locus_tag="SCH06_002659"
     CDS             4284..4700
                     /locus_tag="SCH06_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079179.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPATNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1757 a          816 c          786 g         1429 t
ORIGIN      
        1 aaaaaaaaaa gaaaaatccg cttctgcgaa ttcttctttt ttcattttgg ggcgctgccc
       61 taatccctaa gtcccggtta ttcaatagca tggaaactca aagaataaga cgttccctgg
      121 aataaaaaaa aggctgctcg ttcgagcagt ccatacatag gaaaatgaaa aaacgacgtc
      181 ccttactgag aaacgctatt aaacttttaa caaatcctct aaaaaataac aagtctttaa
      241 aaagtgaccg gtaaaaatgc acaaagaact aaaaaagaga aattgcatca aatcaagcat
      301 tagaagctag taactagcta gaccaattga aaatcacaaa gtgagcgcct gtatctattg
      361 ctacaggcgc tacttggcat agtgtacatt atgtcaacaa gaatttaata taacatattt
      421 ttctagtttg ttataacaat gccactctaa caaaaatgta agcattatcc ttattaaaag
      481 ctccttgaca aggactatac cttttatttt atgattttta catagaaaac gttttctcta
      541 ttttttgttt agaggtgatt tttatgattt gcaagaacaa gaaaaaaatt attgctatta
      601 ttgctagttt ctctttgatt tttagtactg catgtactgt cttattaaca aataatgcta
      661 atgttgaagc tgcaagctct tcttacaaac ataatcatgc tggttataga tgttacaaaa
      721 tgagttatta tgtaagtcct tctaaatgca aacaattggc tcgccaaact aataaactta
      781 ataccgtctc agctattgca aactttattg gactatctgg attaacaccg gggattatat
      841 cattagtttt cggatcagca gttagtgcta ataatgtatt tgttacagcc gctagaagag
      901 gaaaaggcgt tcaattaaat tatattgccc attttagtaa taccactacc tataattata
      961 gttctaacca aaattatgtt ataaaataat taaaacttta aactaggagg aatgctttat
     1021 gaaattaaca aaaattgctg taattttagc tgttattgct ggcattattt tatattttgt
     1081 attgcctgct aatcaattct tcctttactt tggaatacct gcgattttaa tagtaaatgg
     1141 cgtaagaatc tttgaacaac gaaaaaaatg tagctctacc taatcgttac aaaacaacaa
     1201 tttcaccttc ggtgaaataa gcgaaacttt acaaaaagtg gctagcaaat gctagccttt
     1261 tttgtattgt agagcgtgaa ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1321 aagcggttat ttgcaccaaa tacctccgta tttggctagc aatccttcta aaaaatacac
     1381 ctatcgatca gagtcaaaac aaatcaattt tcgagtgagc gaatccgaat ttgcaaagct
     1441 gaagctttgc aaatgagtgt gccggcttcc gtaaaaatac atatggctat aatttgcgtt
     1501 ttaaggcgtt ttaaacgttc tggtatataa ttataccaaa acaactttaa aacgccttag
     1561 atctaatttt agaggtctta tagaacattt tagggttgtt agggcttgcc ctgaccgcct
     1621 gtaaggcgct ttgagaacaa gataagggtt ttatactaag actgtcttaa aacggcttaa
     1681 acaaacgctc agaacttttc aaaggagttc tttatgaact gtttttaagc aaaggagcct
     1741 ttaggcgact gcgcagtata atgtgagagc gtagcgatca cacattttta gtgaccgtag
     1801 ggagcgagtt tcccagttta gaaaaattcg cgaacttgtt tgaggaaaaa agcaggagtt
     1861 ttttaggcgg gaaattttgc ctcctctttt ataatctctt tttaaacctc tttttaaacc
     1921 tctttaccgt cggctgtatg cttactctcc caaggtgtgc agaatctttt gggggtcttt
     1981 ttgtctgttt ttaggggtct ttttgtctgt ttttaggggt ctttttgtct gtttttgggg
     2041 gtctttttgt ctgtttttag gggtctttaa ttaggggctt gacccctatt agaaagctct
     2101 ttataatttt gttaagtagt taatcttgaa ggaggatttt atggcaaatg aaattgtgaa
     2161 ataccaccat gaattaaata cgattccttt acgcaaattt acgtcagtag aaatgaattt
     2221 attcttctct atagtatcta gaatgcgtga cgtaggcgat aaaaaagtac aatttacatt
     2281 cgaacaatta aaagatttaa gcaattataa agcaactgca aatgttcgat tcatagatga
     2341 tttagaaaca acgtatgaca aattaatgga tttacgtttt ggtagaagaa gtgctgacgg
     2401 tttgcaacgt gaacgatttg ttttatttaa tcaatttaaa atcgatggaa aagctgatat
     2461 tccttttgct gaaatacaag tccatgagaa agccttaccc ttacttaata atcttgaaga
     2521 atgggttcga tattctctcc aacaattcaa tgaattagaa agcagttatt ccaaaaccat
     2581 gtttagatta ttaaaacaat acagaaccaa aggaattgcc tatttttcaa aagaagactt
     2641 tcatgaatta cttgatatcc ctaaaagtta tagagaaagt gatataaata aaaaaattat
     2701 aaagcctatt cgccaagaac taaccgcaat cttcaaaggt ctgacaatca aaaagaaata
     2761 cggaaaagga agaggaaaac ctgtcattgg ctatcaattc acgtttaaac ctgaaataaa
     2821 aaaagcagac gactttaata aacacgcacc aacaaaagaa gaacaaaata aagctttaga
     2881 actagttaat caacaaattt actctgaaaa agaccccact tcattacaag aaaaaatcaa
     2941 agaacagaaa cgaaaattag aacttttaca acaattagaa gagctagaaa gaaaacaaaa
     3001 taatctgaat aaagaaaata aggagattaa cgaacaaata ccagataaca attccgatat
     3061 tcccccagaa ttaaaaaaag gcttactaga taatcttcaa aacttattta aagaataagg
     3121 ggtttttatg acagataaaa ctatcaaaga attagcagat attctaggtg tttcaaaaga
     3181 taaagtgaag tatcaactga ggaaattacc tagtaatttt acctacaaaa aaggaaatat
     3241 tatctacctg aaaaaagaag cagtaacaac aattacaaag gttttatcag gtaatgagcc
     3301 gggtaactta cctagtgaat tacctgattc attacctacc gattacctac tcaaggagat
     3361 tgaaactaag aataatcata ttgaagaaaa agataggcaa attgaaaaac ttcaactagc
     3421 tttagaaaca caacaaaaat tactcgacca gcaacaacaa ctcaccctgc aagccaacca
     3481 acaaatcgag aaactgcagg aacaactaca gttgacttat acggaagaat cttcggaaaa
     3541 taaatcaacg actctttctg aagaaacaga atcgatagaa aaacaatcaa agacggagaa
     3601 aaaatggtgg caattctggc aataaaacca gcaatttaaa ttaataaaaa ttgctggttt
     3661 tattcttctt tttgcttttg cgagcagagc aacatgggcc catgttgcga tattttggtg
     3721 gcgccccaat ccccgttttt tcgttgaatc ttactcggac tgcactcgtt ttacagctga
     3781 tttttctgaa ttttgaaaga gcataaggaa acgtggtatc actttcttac gaaaggtgct
     3841 agataagctg tgcctatcac gtttctcaga aaaaaatttg ctatcacttt tttgccattg
     3901 tggctaggct atgtatagtg ttttggcgaa aaatagctat acaaatacta tatttgtatg
     3961 atatacataa attatatact gatacgaaag gaaaatttcc atggacattt tagttcgaaa
     4021 tatcaatccc aaaattatta caagaataga taaacgttgt caggaactaa caaccaaaac
     4081 gggcaaaaaa tggagtcgaa atcaatacct aaaaatttta atcgaaaacg attttgacca
     4141 cgaacttatg aattacaaaa aagatcaatt cgatttatta ttcgaaaaat ttattgccat
     4201 tcaagcagaa aatacgaaca tactaaatga ctatgttcac acaaacaacc aactcattga
     4261 aacacttatc ggaggaatat aacatgagaa aaacttctgt tcaaaaacac gtaacccttt
     4321 atcccagtca cgttgacgtt ttagattcca tcatcgaaaa aaatccagac gtcaacaatt
     4381 attcagaagc cattcgcttt ttatgtatga gttatgaacc tgctaccaat acaaccacaa
     4441 ccagtaacca agcaaaactc aatgccatgg gaaaagaaat ttctatcatg acagaaatca
     4501 tggcagaatt tgctgattta tatctaaaag atactggtgt tcttatcggt acaaattcta
     4561 aagtatatca agaagtgaaa gaaaaaattg aaaatcaact caatccttcc cgacgaaatc
     4621 aacccaaaaa tcgtcaaaaa gaaaccaatc aaacctttac ttctggaaat tttgacccaa
     4681 caaactttct aaaaagataa aaaaagaaac cgaaaaataa aaaaattcct cgatttcttt
     4741 ttagggatcg gtcttccagc aagatttgca agttggtacc aacttgcg
//
LOCUS       DARBDN010000142         4774 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000142 DARBDN010000000
VERSION     DARBDN010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.146"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..538
                     /locus_tag="SCH06_002660"
     CDS             <1..538
                     /locus_tag="SCH06_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEG1079180.1"
                     /translation="KQIDKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLA
                     GFTKEVEADVYVMTHTTAPFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPF
                     NYELDNIPRTQDLPPLYEETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEA
                     EDFMIADAIYNHLILQGS"
     gene            557..2140
                     /locus_tag="SCH06_002661"
     CDS             557..2140
                     /locus_tag="SCH06_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HEG1079181.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            2275..2853
                     /locus_tag="SCH06_002662"
     CDS             2275..2853
                     /locus_tag="SCH06_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079182.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            2799..3317
                     /locus_tag="SCH06_002663"
     CDS             2799..3317
                     /locus_tag="SCH06_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079183.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            3325..4365
                     /locus_tag="SCH06_002664"
     CDS             3325..4365
                     /locus_tag="SCH06_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEG1079184.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            4614..>4774
                     /locus_tag="SCH06_002665"
     CDS             4614..>4774
                     /locus_tag="SCH06_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079185.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         1748 a          546 c          943 g         1537 t
ORIGIN      
        1 aaaacagatt gataaagtgt atgtctattg tagtaaccca gatattaaag aatttatacc
       61 agaaggtgta acatttttaa agagatctag ttccttagat caggatacaa cgagtattac
      121 acaggtatta gccggtttca caaaagaagt agaggctgat gtatatgtaa tgacacacac
      181 aacagcacca tttattagcg aaaaatctat tgaaaaagga ctagatgccg tgctgacagg
      241 agaatatgat tctgcatttg ctgcaaaaaa attgcaagat ttcttatgga aagacggtga
      301 accatttaat tatgaattgg acaatattcc tagaacacag gatttgccgc ctttatacga
      361 agaaactagt ggattttata tttataatcg caatgtgatg accgagttgc atagaagaat
      421 tgggaaaaaa ccttgcatag ttgaagtagg tgagattgag tcagttgata ttgatgaagc
      481 cgaggatttt atgattgctg atgcgattta taatcatctt attttacaag gtagttaaga
      541 cagggggaag gttaggatga acaatgtaca gattttagat tgcacactta gagatggggg
      601 ctattgtaac aattgggaat ttggatttga taatacaaaa aaaattattt ctggacttat
      661 agaatcagga attgagatta tagaatgtgg gtttctcaca aataaaacag tatacaataa
      721 aaatgttaca aaatatacga ccttagaaga attagcacag ataattcctg aaaaaagaga
      781 aggaaaatta tttgtagcaa tgatgaacta tggcgaatat aatatagagg atcttccaga
      841 ttatgatggt tcatctattg atggaattag gattgcgttt cataaaaaaa attgcaatga
      901 agcgttgaaa ttatgtcgtg agataaagaa aaaaggctac ttagtttttg ttcaagctat
      961 ggtatctctc aattatacag atgaagagtt tttagcagta ataaaaaatg tgaatcagtt
     1021 taaaccatac gctttttata ttgttgatag ttttggaatg atgaaaggaa aagatttaac
     1081 tcgtcttttt tacatgattg agcataatct agaaaaagat atacagatag gttttcactc
     1141 acataataac atgcagcttg catattctaa tgcacaaaaa cttataaccg tacaaacaaa
     1201 tcgaagcctg attattgatt cttcggtgta cggaatggga agaggagcag gtaatcttaa
     1261 cacagaacta tttgtagaat atttgaatga taatgcagga aaaaaatatc aattaaaacc
     1321 attattatat ataattgatg aaatactaaa tagtttctat cagaagagtt attggggata
     1381 ttcattacca aactatattt cagcagttca taatgctcat cctaattatg caagctatct
     1441 gtcatataag aatactttaa caattgaagc aatgaatgaa atattcgaaa tgatggatga
     1501 agaaaaaaag gtatcttatg ataaacaata tatagaagat ttatactaca aatatatgga
     1561 aactgggaaa atacaggagg aatatatgga agaactgaga aaatttctct cagacaaaaa
     1621 aattctactg attgcaccag gaaaaagttc tgtagatgag gtagaaagaa taaaagagtt
     1681 tgttaccaaa gaagaagtcg taataattag tgtaaatttt gaatattctc atatagatat
     1741 agattacgta tttttaagta atttaagacg ttttcatgaa ttaccgaaag aaagcagaac
     1801 taaatgtatt gttacatcaa atatacaagc atcggatgta tatttacgga cgagttataa
     1861 aaagttgtta tctgaaaggg aagttgtaag agacaatgca ggattaatgg caattagatt
     1921 tttagccgat atgaatgtgg atgaaatatt cttagctgga tttgatggat attcacataa
     1981 tgaagatgag aattatggtg agcaatccat ggaaattata acaaaatttg cattattaga
     2041 tgcaatgaac gtgcaaatga gagatgaatt gtcagaatta gctaaaaaag taaaggtgac
     2101 atttttaacg gatccacgtt gggttcgaat tgataagtag tagtaataat gtttttaaaa
     2161 ttttgataaa gagatagtga gagaataaaa atgggtaaag tcttaaataa aaaagaagaa
     2221 aaatatttaa gggacgatgg ggcgagatga aactctaatt ttgaactttt aagaatcatt
     2281 tctatattgt gtattgttgc ttaccatgct aatttgcgtt taaattataa tgcagacgga
     2341 attatagtac atggttcatt aactgctaac cagattttct tgaattatat tggtatttgg
     2401 ggtcagctag gagttaattg ttttatattt atttcggcat attttttaag tgagaaaaga
     2461 aacattcact ttgaaaatgt tttgggaatt gtattagaat gtatttttta tagtgtatta
     2521 gtttatggaa ttctttgtgc atgtggaata gaaacatttt cattgaacag ctttgtaaaa
     2581 gaaatattat catttgctct aggtagatat tggtttatta catcctattt agcattgtat
     2641 attctaagtc cgtatttaaa tatcatgctt aacaatctgg aaaaacttca gttgcaaaaa
     2701 ataagtatgt tattgtttat aggtgtatgc tgttatcgta tgttatttaa aacatctttg
     2761 tttggggatt gtgctgtttt aattgcacta tatgtcatat gttatacact gaaaaaaacg
     2821 ataataatat ttttgagaga cacagaatca taggaacaat tgtatgtata acagttatac
     2881 cacttctcat atccatagga atacttttca aatttatacc aaatgcaatg gttaaccaga
     2941 tggttcatat tggttctcca ttgatggtta tagcaagtat atttttattt tatgtattta
     3001 aaaatttttc attttacagt aagtatataa ataaacttgc gagaaccagt ttaggggtat
     3061 atattttaca tgaaaatcat tatttcattg atggtatgaa gtctagaggc ttaatatggg
     3121 atgggatatt tggattaggc aaaaggtttt tagataggga tttttggatt tggtttataa
     3181 ttgcagttgt agttgtgtgc ataatttgca tggctatcga tgttgtaaga gaaaaatttg
     3241 aaagacagat ttttaaaatt aagagtgtaa agaacctgtg taaacttatg aatcatgtta
     3301 taaatatata cccataatta ataaatgagg agaaaagaag tgaaagttat atcattcgga
     3361 gaattattat tgagacttgc agcacccggt tattcaaagt tatttcaaag agatagtttg
     3421 gagactacat tctgcggagg ggaagctaat gtagcggtat ccttagcaat atttggatat
     3481 caatcagaat ttataacaaa gcttccggat tcagatgttg gatatgcggc agctaatgct
     3541 ttgcgttatt ttggagtaaa tgttgataat attatatttg gagagggacg catgggactg
     3601 tattatttag aaaaaggagc agctcagaga ccatctaaag taatttatga cagaaaattt
     3661 tctgcaattt cgttagctga tagtgatgaa tttaagtgga aggagatcct aaacgatgca
     3721 aattggtttc attggacagg gataaatcca gcattgtctg agaatctctt tgagacgtcc
     3781 ttagatgcat gtcaggctgc caaaaaaaga ggtataacaa tttcttgtga tttaaattat
     3841 cgatccaagc tttggacatc agaggaagca aaagaaaaga tggaacagat actaccattg
     3901 gttgatattt gtatttgtaa tgaagaagat gcagaaaaag tgctaggaat taaagctgag
     3961 catacaaata ttaatagtgg agaattaaat aaagatggct atgtgcaggt ggctagggag
     4021 attcacaaga agtttggatg taggtatgta gctacaactc tgcgtagaag ttattcggca
     4081 agtagaaatg gttggagtgc aatgttatac gaagcagaaa aagataaagc gtatttttcc
     4141 acagaataca acatacaaat tgttgatcgc gttggtggtg gagacagctt ttctgctggt
     4201 ataatatatg cgttatgtga aaatatgtcc ggacaaaagg ctattgaatt tgcgactgca
     4261 tctagttgtt taaaacatac tatagaaggt gattttaatc gaactacaat tgaggatgta
     4321 tataatttaa tgaatagcgg tggaaatggt cgcgtgttgc gttagtcaac atataaagat
     4381 aaatcacagt aatttttatg gtgattatct gtcttagtag tgattagaat aacgtgaaaa
     4441 taaattgttg agcgtttata ctgttttgaa aaataaattt aacatattga aaaatacaaa
     4501 tatatacgta tattataaag cgccgattgt aaaattaagc tagacaacta aaacagtcat
     4561 ttgtgctaca ctcaaaatag ttccgaccaa agaattataa ggagtgagtg caaataacct
     4621 atacctatct tacaacggat gaacttgtaa taatagagtc ttatttgaaa attaaccaat
     4681 ctgttgctaa aactgcgcat tgcttgaatc gttcaagtca aacgatccat aaagtatatc
     4741 tgttcttcaa gcaaagaaaa tcagccttag aata
//
LOCUS       DARBDN010000143         4750 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000143 DARBDN010000000
VERSION     DARBDN010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.147"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..547
                     /locus_tag="SCH06_002666"
     CDS             <1..547
                     /locus_tag="SCH06_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079186.1"
                     /translation="KIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGI
                     DETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLL
                     ISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSE
                     EKILLPENWAELRKLVEYGII"
     gene            534..1955
                     /locus_tag="SCH06_002667"
     CDS             534..1955
                     /locus_tag="SCH06_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEG1079187.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1968..2975
                     /locus_tag="SCH06_002668"
     CDS             1968..2975
                     /locus_tag="SCH06_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEG1079188.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2987..3991
                     /gene="neuB"
                     /locus_tag="SCH06_002669"
     CDS             2987..3991
                     /gene="neuB"
                     /locus_tag="SCH06_002669"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HEG1079189.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3988..>4750
                     /gene="neuC"
                     /locus_tag="SCH06_002670"
     CDS             3988..>4750
                     /gene="neuC"
                     /locus_tag="SCH06_002670"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HEG1079190.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMY"
BASE COUNT         1689 a          609 c          842 g         1610 t
ORIGIN      
        1 aaaaattccc aaaatagatg aaaacagtaa attgatgaaa aacatacaat caatctttgg
       61 gatagaagaa gtttttgtcg gagataaatg tatctttttt gatcaacctt tattatctga
      121 tggttatggc atagatgaaa cagatatttt cgctaaagta aatagtatat tttctggaaa
      181 aaaagaaact ttaattaagc ttcatcctag agcaaggaca aatcgttatg gtgaaaaaaa
      241 catattgaat tccagtttac cgtttgaagt cttgctactt gaaaatgact tctcttcaac
      301 acttttgatt agtcctatat ctacaatttc tttttcacca tctatgatgt ttgaaaagac
      361 gatcaactct attatgttgg ctaaattaat tttaaatgaa tatacagcat tatctgaaga
      421 taaaaaagaa acattgacaa atattgttct tttctgtgaa cattataacc gtctatcaga
      481 agaaaaaatt ttactcccag aaaactgggc agaattaaga aagttggtag agtatgggat
      541 tatttaacac actttccaag tcaaaattag ttaagtccag tttctggtat actataggga
      601 atttttttat taagggaatt tcattcataa ctattcctat ttttgtaaat attactactc
      661 aagcagaata tggtttgatt aataatttca cttcatttgt atcaattttt tcgattcttg
      721 ttgggctaag cctaaattcg gcaattaata atgcaagttt tgactataaa gatgacataa
      781 atgaatttat gtcatcggta ctttctctag ctacactttc gttaattgtg ttcttattaa
      841 tagggaacat atattttttg ttttcaaatg ctttttttga tatgaaccaa cttgtattta
      901 atttgatgtt attacaaagt tttgctagtt ttgtaattag ttatatccag tcttatttta
      961 cgattaactt taaccatttt aaatatttga ttttatcttt tatatctact tttttgaata
     1021 ttgcaatctc tgtagctttg atgcagacat tatattttga tgataaatat gttggcagag
     1081 tagtcggcgg aacactgtca tttgtgttga taggtttagt aatttattta agaataatga
     1141 taaagggtgc tcattttttt gataaaaaac agtggagata cgctttaaaa atctctttgc
     1201 cgctaatccc acattcctta gcaaatatag ttttagcaca attcgataga attatgatta
     1261 attcttattt aggtcctgct gcggggggaa tatattccta cattagtaac ataggtatta
     1321 ttctaagcgt aatatggatg tctactaata acgcctgggt tccatggttc tatggtgaga
     1381 tgagtaaaaa taatgaaaaa aaagtgaaga aagttagtaa ctattattta gtagtcttta
     1441 ctttgattac gatgattgta atggtagttt cgattgattt agcaaaattt atggctccga
     1501 aagactatta ttctgggtta tctttagtgg ttccgataac cttaggctat ttctttcagt
     1561 ttttatatag tttaccagtt aatgctgaat tttatgagaa aaaaacatcg tttattgcga
     1621 ttggtacagt agcaagtgct atagttaata tactattaaa catgattttc atacctaggt
     1681 taggaataat tgctgctgga tacacaaccg tatttacgta ttttttactt tttatttttc
     1741 attataatat cgctaaaaaa attacgaata aacaattatt tgacacaaaa aaaatatgta
     1801 tcataataat ttttgtatca attttttctt tgatacttca tattttaatc aatcaaatgt
     1861 tgattcgtta cgttttgaca tcattattga taattagttt agttatatat tttttaaaga
     1921 ttaagaatcg aattatagat gactataatt cataggagga gatataagtg tttaaaggaa
     1981 aaacaatatt agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt
     2041 taaaatatga accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata
     2101 tgcaacaaga gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact
     2161 ctcaaaggat tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga
     2221 aacacgttcc agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa
     2281 ctcaaaatgt aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta
     2341 cagataaagt agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat
     2401 taataatagc tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt
     2461 ttggaaatgt catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa
     2521 acaataaaga tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg
     2581 atgctgcaag attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct
     2641 taaaaatgcc ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg
     2701 atacacatga tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa
     2761 aattatatga agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa
     2821 tgtatatcat tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa
     2881 ttaaaatcac tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta
     2941 gaatcgcaaa agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt
     3001 atatgtaatt gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag
     3061 tattgataaa gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa
     3121 taagctagtt tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga
     3181 cagttctcaa tttgaaatgc taaaaaaatt agaattatct caatctgatt ttattagaat
     3241 aaaagattat tgtatacaaa ataaaattga ttttttgtct actccttttg atgaagaaag
     3301 tgcagacttt ctaaaacaaa ttggtgtaca aggatttaaa attggctcag gagatttaac
     3361 aaatttacct tttcttagaa aaatagatat gtatgggttg ccagttttat tatctacagg
     3421 tatggctgat attcatgagg tcagtgaggc tgtagattgt ttcatagata gtccagttac
     3481 tattttacat tgtacttcaa attatccggc tagttctgaa gatattaatt tattggcgat
     3541 taacacatta aaagaaatgt tcgggatacc cgttgggtac tccgatcatt cattgggata
     3601 tgatgttggt atttgtgctg ttgcgatggg tgctaaggta attgagaaac attttacctt
     3661 ggataaggaa ctacctggtc cagatcataa agcttcttta gatcctcagg aatttgcaga
     3721 ttttgtaaag catattagaa acactgaaat atttttaggt gatggtgtta agcgagcaat
     3781 gccttctgaa cttagtacaa aagaagtatc aagaaaaagc ctagtggtca ctgagaattt
     3841 aaatgtggga gatattctta cagagaaatc tcttacaata aaacgtcctg gaaatggaat
     3901 agctcctaag tttttatatc aatatattgg caaaaaagtt aaaagaccaa taagtgcaga
     3961 tagtgttctg cttgaggaag atgttgaatg aaaaaaatac ttatagtaag tggaacacga
     4021 gctgattatg gaatatataa acctgttgct gagaatttac tacaagataa ttgggatgta
     4081 tcatttgttg tttctggaat gcatttatcc cataaatatg gatttactaa agaattgatc
     4141 ttagctgacg gatttagaat tagtggagaa gttcaaagtt tgtttttaga gaacaataag
     4201 ggaaacatgg ctcggtctgt ggcattagag ataaatggtt tcacaaatat atttgaacaa
     4261 actagccctg attttgtatt attactaggg gatagaggag aaatgttggc agctgcgata
     4321 gcttgtttgt atcttggaat caaaacagca catattcacg gaggcgaagt gtctggtact
     4381 gtagatgaat caataagaca tgccataacg aaaatagcat ctgttcattt tgctgctacg
     4441 gaaaaaagca aagagcgttt aataaaaatg ggggaagatt cttggagagt ttttcccgtc
     4501 ggagctccta gaatagatac tattttaaat aatagattac ctagttttag agatataaaa
     4561 gaaaaatatc atctaaaatt tgaaaagaaa aaatacgttt tgcaagtatt tcatccagtt
     4621 gtaaccgaac tagaaaatat agaaaaacaa attttagctt tgatcaattc aatggaacaa
     4681 caatctcaac caattatttg cattttacct aatagtgatg ctggtagcga aattatcaga
     4741 aaaatgtacc
//
LOCUS       DARBDN010000144         4712 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000144 DARBDN010000000
VERSION     DARBDN010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.148"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            106..357
                     /locus_tag="SCH06_002671"
                     /pseudo
     CDS             106..357
                     /locus_tag="SCH06_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            450..1244
                     /locus_tag="SCH06_002672"
                     /note="aph(3')-IIIa"
     CDS             450..1244
                     /locus_tag="SCH06_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEG1079191.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1654..1737
                     /locus_tag="SCH06_002673"
                     /pseudo
     CDS             1654..1737
                     /locus_tag="SCH06_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1786..1869
                     /locus_tag="SCH06_002674"
     CDS             1786..1869
                     /locus_tag="SCH06_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HEG1079192.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1994..2731
                     /gene="erm(B)"
                     /locus_tag="SCH06_002675"
     CDS             1994..2731
                     /gene="erm(B)"
                     /locus_tag="SCH06_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEG1079193.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2994..3857)
                     /locus_tag="SCH06_002676"
     CDS             complement(2994..3857)
                     /locus_tag="SCH06_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HEG1079194.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3859..4131)
                     /locus_tag="SCH06_002677"
     CDS             complement(3859..4131)
                     /locus_tag="SCH06_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEG1079195.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4148..4357)
                     /locus_tag="SCH06_002678"
     CDS             complement(4148..4357)
                     /locus_tag="SCH06_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HEG1079196.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(4455..>4712)
                     /locus_tag="SCH06_002679"
     CDS             complement(4455..>4712)
                     /locus_tag="SCH06_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HEG1079197.1"
                     /translation="MIGFVPYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKV
                     STWSKNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENEKE"
BASE COUNT         1446 a          796 c          865 g         1605 t
ORIGIN      
        1 ttcttgggag ttttgagact actatatgcg tttttttgtt gatttaccaa catgtttaga
       61 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
      121 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      181 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      241 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      301 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      361 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      421 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      481 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      541 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      601 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      661 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      721 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      781 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      841 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      901 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      961 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     1021 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1081 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1141 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1201 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1261 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1321 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1381 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg ttattttgta
     1441 catttaactt gacggtgaca tctctctatt gtgagttatt agtggtacag ttttcaaccg
     1501 ttttaattat aaaaaagtgg tgcattttta aattggcaca aacaggtaac ggttattgca
     1561 ggtgtatttc ttatctatgg gtttaacatg gattttatca ttaaaatcat gagtattgtc
     1621 cgagagtgat tggtcttgcg tatggttaac cctaaagtta tggaaataag acttagaagc
     1681 aaacttaaga gtgtgttgat agtgcattat cttaaaattt tgtataatag gaattgaagt
     1741 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     1801 atgcgttatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacgca
     1861 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     1921 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt gtttatagat gtaatcactt
     1981 caggagtgat aacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     2041 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     2101 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     2161 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaatactcg
     2221 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     2281 aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     2341 aagccgtgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     2401 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     2461 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     2521 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     2581 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     2641 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     2701 tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt aaatttggaa
     2761 agttacacgt tactaaaggg aatgtagata aattattagg tatagggcac ctctaataac
     2821 taccaattaa ttcacctcaa aatgaaatta gaaaaaaaca gcgaaatttt taaatctatt
     2881 tcttatcgat acaaattcct cgtaggcgct cgggacccca acatgaggaa atgtttttat
     2941 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaata
     3001 cctggaagtt taggtgtttt gggtattggt ggtgtaggtg gctgcaagct ttccaatttt
     3061 tgttgaattg ctttaaattc aggtgtctct tggtgtttat ttagaaccat tttttgctct
     3121 attcgttcta aagtcggttg aatttctttc cctgatactt tacgattcaa ttctttttct
     3181 aaggtttctt ttggactaat agaaggtgtt tccaaacttg aatagagttt tactccttct
     3241 ctgttatata gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
     3301 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctggc tgtcattgga
     3361 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
     3421 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
     3481 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
     3541 aaacggctta tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg
     3601 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
     3661 ttatcaatga caataacatt cccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt
     3721 ttccctgacc ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt
     3781 ccttgaatca attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa
     3841 ttgactatat ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg
     3901 attcattgac cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag
     3961 atttacacgt tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc
     4021 atttttattt aattcatggt tcaaaacata gtttaatact cgattataaa cgcttgccga
     4081 taattcgtta atgatctcta tttcaaatgt tttttcatac gtaactgcca tttcattttc
     4141 actcctttta aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca
     4201 taacttcttt tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt
     4261 cagcacgaac acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat
     4321 catttcgttt tgctttttgt gcgcctaaat ttcccacaat cactcacttc tttctatttc
     4381 ttcttactct tattttatca tcaacaatca caaatcacaa gtgatttgtg attaatcact
     4441 tgtgatttgt gattctattc tttttcgttt tctaattgaa taattcgctc aagcatttca
     4501 aaaaatacgt tcttatacat ggataaaact tttttgtcat agcctttatg ctctgtaatg
     4561 ccgtttttag accaggtact tactttatta cttcgcttga taatattttg gaaaaccaag
     4621 ttatcttctt tatgttgctt atacagttct tccaggtttg attttatcgt tgcgctgtcc
     4681 gtatcaacta aataaggaac aaaaccgatc at
//
LOCUS       DARBDN010000145         4690 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000145 DARBDN010000000
VERSION     DARBDN010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.149"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            35..1663
                     /gene="treC"
                     /locus_tag="SCH06_002680"
     CDS             35..1663
                     /gene="treC"
                     /locus_tag="SCH06_002680"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEG1079198.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGENMSEGNGWNALFFNNHDQPRALNRFVVIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(1723..2904)
                     /locus_tag="SCH06_002681"
     CDS             complement(1723..2904)
                     /locus_tag="SCH06_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEG1079199.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            3156..4679
                     /locus_tag="SCH06_002682"
     CDS             3156..4679
                     /locus_tag="SCH06_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEG1079200.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
BASE COUNT         1718 a          821 c          943 g         1208 t
ORIGIN      
        1 aggtaataaa tcagttgaat ggaggtaaat atccatgaca tttaaagaca aagtcattta
       61 ccaaatctat cccaaatctt acaaagacag taatggtgat ggaattggag atttaaaagg
      121 aatcaaagaa aaactcccgt atctgaatga tctaggcatc gacatgattt ggctaaaccc
      181 tatttatcca agccctcaaa aagacaacgg ttatgatatc tctgattaca cagccatcga
      241 tcctatcttt ggtacgatgg aggaattcga acagctaata gccgaagcaa agaaataccg
      301 gatagaaatc atgctcgata tggtgctgaa tcacgtttcg acagaacatg aatggttcaa
      361 aaaagcacta gcaggggacc agcattatca ggacttcttc attttaagag aagagccaac
      421 ggattgggta tcaaaatttg gtggaagtgc ttggtcgcca tttggagata cggggaaata
      481 ttatttgcac ttatatgatc ggacacaagc tgacttgaac tggcggaacc aagcagtaag
      541 agaggaacta ttcaaagttg ttcgtttttg gatggaaaaa ggggtaaaag gattccgttt
      601 cgatgttatc aatgttatcg gtaaagacga acaattgaaa aataataaag aaaatgatgg
      661 caaacctgaa tatacggaca aaccaatcac ccatacgtat ctaaaagaat tgaaccaagc
      721 aacgtttggg acggattcca ctatcatcac agtcggtgaa atgagctcta cgacgatcga
      781 aaattgtatc ttgtatacag aacctagtag agaagaatta tcaatggtct ttaatttcca
      841 tcatttgaaa gtcgattatg aaaatgggaa taaatggtct actcctccat ttgattttgc
      901 agaattaaag cgactatttc atacatgggg agaaaatatg agtgagggta acggctggaa
      961 tgctctattt tttaataatc atgatcagcc acgtgcgctc aatcgatttg tagttatcga
     1021 tcagtatcga aaacaaggag cagagatgct agcaaccatg atccatttga accgtgggac
     1081 gccctatatt tatatgggag aagaaatcgg catgatcgac ccagactatt catcgatttc
     1141 cgactatatt gacgtagaaa gtttgaatgc ttataagtta ctccttgaac aaggattcac
     1201 agaaaaagaa gcgtttcgtc ggatcaaagc aaaatctcgc gataactctc gaacacccat
     1261 gcaatggtca gacacagaac aagcaggatt tactacaggg aaaccttggt taaaagttgg
     1321 aggcaagcta gaagagatta atgtagaaaa agaactatct tctgaagatt ctattttgtc
     1381 ctattacaag aaattgattc ggctgagaaa aacatatcca atcgttgcac aaggagatta
     1441 tcatgcttat gaagcaaatc atccggaagt ttatggcttt cttcgccaat ttgaaggaca
     1501 gcagctgctt gtattaacaa atttctatga taaagataca aggatcgcca tcccagaagg
     1561 attcacagaa gccaatattc ttatcgataa ttattccgat actgttcttc atcaaagtct
     1621 ggagctaaaa ccataccagg caattgcttt gctgaaaaat taaaacaaaa acacaaaacg
     1681 tcgttcctac gagctattct cgtaagatcg acgttttgtg ttttatttaa aataatcttc
     1741 ttcagaaaat gaagagtttt catactctcc tttatcgcca taaaatttat tgtagcgttg
     1801 tttgaattta cggaaaataa aagtaacgag taatttgact aacgtataga taggaatacc
     1861 aaaaataacg cccacaattc ccattagatc acccatgaca agtaaaacga ttaagatcgt
     1921 aatcggatgg atctgtaaac gatcacccat tactcgagga atcaccaagt caccgtggag
     1981 aagttgtacg gcaaaccaga caatgacaaa tttgacagcc ataaaagtag agtcttggaa
     2041 tgcaatgatc aaacctggaa agaaggcgat aaacggccca atatatggaa tgatacataa
     2101 caacccagca gaaatagcta aaacactagc aaattctaat ccgatcagta agaaacaaac
     2161 ccagtagact gctccaagga taaatgaagc aatgatttgc ccctttagaa atgaacccaa
     2221 ttgttgatta gcaatctttg tcaaattttt aaaatctgta cgaaatgctg gtgggacaat
     2281 cgctaaaact gactgataaa atttttgagg atctctcaaa aggaaaaaag cgacaattgg
     2341 accagtaaat aaagtaataa aaatagctgt aacagttgaa aaaatgttgc tgatccgttg
     2401 tgcgccactt tcccaataat ttccaataaa tccagctata tcagacgtca cgtcgtcaat
     2461 agaagcaaaa aattgattaa atgaatcggc aaaaggtgtt ttctccaaaa attgtcggag
     2521 actctcttga aaatcttgaa acaaatctgg caaactactg atcaatgtct ttgcctgttc
     2581 ttcaagaaaa ggaataagcc atatgcttcc aagccccaat aaaaataaaa taatcacata
     2641 aacgataatg actgacaagt tcctcgaaag gtgcttgctc aaacgtttga tgactggttc
     2701 caaaagataa tacaagatca gtgcaaacaa taatgggggc aagatagtag cgataatgat
     2761 tccgacaggc ttgaatataa acgagatctg atggaaaaaa taaatgatca gcgcaagtaa
     2821 gataactatt cctaaaacat agtaagaggt ttttcctcct aaaaagcgga tcaaacgatt
     2881 cgttgtatct gtttcttttt tcactctttt tcctccttta tctataactt cattatagac
     2941 aaaagcgggt ataaaaggaa aatgatagag gttgattgca aaaatatcgt caatcattca
     3001 tataaacttt ctcatcaatt aaaataagaa aacgcttgac agttctttta accatatgat
     3061 aaattaaatc ctgttgctaa aacgtaacta ttacggtttg cgaaaagcga atcggaacat
     3121 tcaaatgaaa gaagatgaga agaggagtgt cataaatgaa acgattgata ggtatattgg
     3181 ccatgctggt tttagcaggt atgttaactg cttgcggggc aagtgggaaa gccgaggaca
     3241 gtaaagaaaa attgagcgtg atgacgacct tttatcccat gtatgatttt acaaaagcaa
     3301 tcgtcgggga tgaaggagaa gtagagttat tgattccagc agggactgat tcccacgatt
     3361 atgaaccttc tgctaaagac atggcaaaga tccaagatac agatatcttt gtttataatg
     3421 atgaaaacat ggaaacatgg gtccccgcaa tccaaaaaac attacaagaa ggcaatgtcc
     3481 atacgataaa agcgacagaa ggtatgcttt tacttccggg aagtgaagaa ggacatgatc
     3541 atgaccatga acacggggaa gaaggccata cacatgagct agacccacat gtatggctag
     3601 ctccaagttt agcaatcaag caggtagcaa acatacgtga tcagctgatt gaagcttacc
     3661 cagaaaaaca ggaagtatgg acaaaaaatg cagcagccta taccgagaaa cttcaagcac
     3721 tccatcagct ttatcaagaa acctttaagc aagcaaaaca aagatctttt gtcacgcaac
     3781 atgctgcatt caactatcta gcgttagaat atggattgaa tcaagtatcg attgctggtc
     3841 tttcttctag tgaagaaccg tctgcggcga gaattgctga actgaaacac tttgttaaag
     3901 aacatggaat caactatatt tattttgaag aaaacgccaa agatagtatt gccagaacgt
     3961 tagcaaacga agcaggtgta tctttagaag tattgaatcc tttggaagga ttgacgaatg
     4021 aacaaataga aaatggagaa aactatcttt ctatcatgga agcaaacctc gaagcgttga
     4081 aaaaaacgac agagacagaa aacccgctag aagatacttt gacccccaaa aaagaaaaga
     4141 gcgtctacaa cggttatttt gaagacgagg atgtacaaga tcgctctctt tcagattggg
     4201 caggaacttg gcaaacagta gatacgtatg tagaagatgg gacttttgat cctgtttttg
     4261 aatataaaga aaaattgaat caggataaga cagcacaaga atataaagaa tattatacga
     4321 agggctatca aacagatatt gcttcaatca agatcagtga gaaagagatg gcatttacgt
     4381 ttaaggatgg aacaacgaaa cgttcaaatt atcgttatgt agggaaagaa atcttgacct
     4441 acgaggcagg aaaccgtggc gtaaggtatc tattcgaagc agaagataag gaaagtggcg
     4501 cttttagata tattcaattc agtgatcaca cgattgcacc ggctgactcc gaacattttc
     4561 atttatatgc aggaaatgaa agtcaagaag tattgctgaa agaaatggag aattggccaa
     4621 cattttatcc agatacaatg gatggacgtg aaattgcaca ggaaatgctt ttgcactgat
     4681 aggcaaaaaa
//
LOCUS       DARBDN010000146         4635 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000146 DARBDN010000000
VERSION     DARBDN010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.150"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            175..519
                     /locus_tag="SCH06_002683"
     CDS             175..519
                     /locus_tag="SCH06_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEG1079201.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="SCH06_002684"
     CDS             520..939
                     /locus_tag="SCH06_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEG1079202.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="SCH06_002685"
     CDS             complement(1031..1381)
                     /locus_tag="SCH06_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079203.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2567)
                     /locus_tag="SCH06_002686"
     CDS             complement(1347..2567)
                     /locus_tag="SCH06_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HEG1079204.1"
                     /translation="MLSNTPTDNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILT
                     LLSVLLAYRHKVILNGPLFASILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQ
                     YIMIGLFGSALSPVVSYITFGMRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGF
                     TLYNIGFTSGLIAMTFTAVLRLFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFY
                     YNSFRLLGIREIFDSSGKLTTDFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPV
                     IGAILSAVGFSAFGCHLKNSFPILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPIS
                     GFYGSFYGVIAGVLHIALVHNVSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKE
                     KKTLGKRIIKKNHR"
     gene            2933..3499
                     /locus_tag="SCH06_002687"
     CDS             2933..3499
                     /locus_tag="SCH06_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEG1079205.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3644..3731
                     /locus_tag="SCH06_002688"
     tRNA            3644..3731
                     /locus_tag="SCH06_002688"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3676..3678,aa:Ser,seq:cga)
     gene            4065..>4635
                     /locus_tag="SCH06_002689"
     CDS             4065..>4635
                     /locus_tag="SCH06_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HEG1079206.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1685 a          778 c          891 g         1281 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaacacc tgtaaaacca agataaaaat actttctttt ctgtgaaacg attcgttttt
     2641 gaggatgaat ataaataacg tcagtttcgt tttccattac acaccttctt tttcattttc
     2701 tttaactata acttgaaatg aaagatttgg acaactatca tttaggtcaa aactaaaaat
     2761 gtaagggaac ccattgaatt taaccaaatt tttttaattt tgcaaaaaaa agttaaagaa
     2821 gactgaaaaa aaatttaaaa tataacgttt tgagtaaaat gtttgcaaaa aatgctaaaa
     2881 atagggtaca ataaaacaac atatactgca gtaaagaagt gggggagttt taatgagaag
     2941 aaaagtctat accaaggatc aaattctaaa agctgcttat gatgttgttg caaaggaagg
     3001 gtttaaagga tttactgcga gaaatattgc taaaaagatg gggatttcga cacagccgat
     3061 ttatctggaa ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt ctatctttga
     3121 acaactaaaa gaagatgttt tccctattga acgtactggt gataaaatca ttgatctcgg
     3181 tttgaactat atctactttg caaaaaagca tcatagtctt tacatggcat tgtacattga
     3241 tgaacatggg gacggaaaga aaatgcatga tttttcatac aattatttcc gtgaaatagt
     3301 taaagaagat gaaagataca atcaattatc ggatgaatat gtcgatgctc tgcatactgg
     3361 tacatgggta gcagtgactg gcttagcgtc attgatgtca tcaaacatca tgcatccaac
     3421 agaagaacaa atcattgcac tgatcaaacg gacaattgac tcgattttag cattagataa
     3481 tcctgaaata atcagatagt gttctatcag tatgaatttg atcggtaagt ccgttggctg
     3541 caaactgtca atggactttt ttgctaaaaa aagcgatttc tgttatttat ctattagaaa
     3601 taggcttgac atttcgtgaa aaaagtttaa aaatagtact tacggaaggt tggcagagtg
     3661 gtaatgcacc ggactcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc
     3721 tgtaccttcc ttatatcaac gattagaggt tgtgaagaag ctgtcctgca tcaagtaata
     3781 agaacggcca aacaaaaata gcttttccta ttttttcgtt tgattgggct tattaccgca
     3841 gatgcaagct tttgaacacc gtttgttcgg aataaggggc tgtgacaaga cttttgtcac
     3901 agccccttat tgttgtactt ttaacctaca atattttttg attccccctg agtactattt
     3961 tttataaatg ctagtaaatc aatcttcttt ggcctttttt tgataaaaaa aatactagat
     4021 gtaagataaa agtgtaaaaa cgatttgttt taggagggga aacgatgtgt accgcaatca
     4081 cttatgcaac gaaagaccat tattttggaa ggaattttga ttatgagatg tcttataatg
     4141 aagtggtcac tattactcca agaaattatc gtttcgattt tagaaaggta aaaaatttag
     4201 ataaacatta tgcaatgata ggaatagcag ctggggtatc caactatcca ctctattatg
     4261 aggctacaaa tgaaaaaggg ttgagtatgg caggactgaa ttttcctggc aatgctgatt
     4321 ataaagaatt acaagaagga aaagataacg ttgcaccatt tgagtttatt ccatggatac
     4381 tagggcaatg ctcaaccata gacgaagcta aagaattatt ggctactatc aatctagtca
     4441 atatcgattt tagtgaaaaa ctacccttgt cacctttaca ctggttatta gctgataaag
     4501 aaaaatcgat agtaattgaa agtatgaaag atggacttca tttatatgat aatcctgtcg
     4561 gtgtgttgac aaataatccg ccatttgatt atcaattatt taatctgaac aattatcgct
     4621 cgctatcaaa tggaa
//
LOCUS       DARBDN010000147         4609 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000147 DARBDN010000000
VERSION     DARBDN010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.151"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(84..338)
                     /locus_tag="SCH06_002690"
     CDS             complement(84..338)
                     /locus_tag="SCH06_002690"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1079207.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
     gene            complement(449..703)
                     /locus_tag="SCH06_002691"
     CDS             complement(449..703)
                     /locus_tag="SCH06_002691"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079208.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(896..1171)
                     /locus_tag="SCH06_002692"
     CDS             complement(896..1171)
                     /locus_tag="SCH06_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HEG1079209.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1143..2096)
                     /locus_tag="SCH06_002693"
     CDS             complement(1143..2096)
                     /locus_tag="SCH06_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEG1079210.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2708..4201
                     /locus_tag="SCH06_002694"
     CDS             2708..4201
                     /locus_tag="SCH06_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HEG1079211.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4336..>4609
                     /locus_tag="SCH06_002695"
     CDS             4336..>4609
                     /locus_tag="SCH06_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEG1079212.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELR"
BASE COUNT         1492 a          774 c          802 g         1541 t
ORIGIN      
        1 gcttgaattc ttgtgaaaaa gttcttcgtg ttctcttaga cataaaaatt cctcctggta
       61 tgttttcttc tagtctacac accttaattt ttctgtctag ttaattgtag cctatccatg
      121 atcggtttat tagacctttg aggtctatat tttttaacta caatcgacct taaatttaat
      181 tgtttcatta gcttttggac atgtttaaga gatactgaaa tcccttcttt taataaaact
      241 tgatggatct ttgtggcacc atagcgttgt ttattcgtaa aaaaaattgt tgaaatcttc
      301 tttttcaact tattatttct gatttctgta gctgtcaacg gtttattctt ataaaaataa
      361 tagacacttc tagggatttc taataaccga cacaacaaag aaacagtgta atccttacac
      421 catttttcaa taaattgaac aagcgaattt aggttttccg agagaatatg gctgcggctt
      481 tttttaagat ttcaagttcc tcatttaaac gagcattttc ttttctcagt tcagctactt
      541 cttttccagt cagtcctgtg gactgatcag gtaaatataa attcttccat ttgtaaatcg
      601 ttgcttcaga taagccatat tctttcgcta accctcgaac agaacgtcca gtttgattca
      661 gttcaacaat catttgttta aaattttctt catatcgggt cataaaaatt catcctctcg
      721 tagataagtt taatttattc ttgtctctac gaaaagctgt ctaagatttg atactaacac
      781 caaatgttgt atacccccaa acaatacaca tattttgaag gattaggatt aataaagcta
      841 aaaatatagt aagtatacta aatatattta ctatatctag tatacttact atattttaat
      901 cttttgatcg tctattatat ataatccgtt cctcgtcgtt taaagtatca acataggcgt
      961 ccattgcaag tttgactatt tcatacatag gaatatcttt tgcataacta agatcccgaa
     1021 tggtttttag tacgggagga tctacttgaa ctggttttct ttctttcgca gtgtactttc
     1081 gttcccctaa ctcgacatta atatcatctt taattgaaat atcttcagca ccaattttct
     1141 tcttatcttt gttcgttggt aataatgcca tttagtttaa tctcctttcc aagaggtagg
     1201 atatgattgg ccattgagtc agcatattta ggtgtataat caaatccttc aatatcacca
     1261 tgttgttcat agtattcaat tctttcttct aattctgtaa agatgtctgc aaaaatagcc
     1321 caccatcttc gatctacata atcatttaat tggataccat tctcaccata catttctaac
     1381 cgatccgagc ctttaacaat gcttttaaaa atgtttgatt caccatactt atcaattgtt
     1441 ttttgatagt ttgcgtgttg agaggaacgt cgcactgaga aaagaacagg caaaattcca
     1501 atgatttgaa gatgagactc ttcaaaattc gtgacaatcg gaactaaaac tttattaata
     1561 aaatcttctg ttccttccat tgcgtaccgt tttaattctt gcattgcaat aatataatct
     1621 gcagcagtta agaatgcacg aaccacatta tctgttgatg gtgggcagtc gataaagata
     1681 taatcgaaat tttttctcaa ttcttctaaa ggtttaatga aggccaatga tctcttacga
     1741 cgatcaggat atttttcgga caagtattca ttaagttctt cagatccagg agagccagcc
     1801 ataatatata aatgtggact tacttgagta atacctgaaa cccagtcccc ttttttgatt
     1861 gctgcagaca tggatcgatc aaagctagta atttgatacg ttgatccaat gttggaagta
     1921 gtatttcttt gttggtcata atcaattagc aacacgtctt tttcaaaaag ttgactagaa
     1981 acaatcgcta ataaatcatt gtctgtagtc ttaccaatgc cgccttttct acctgtaagc
     2041 attacaactt ttcctagttt atctgatgtt ttaaatgcag tccgtaagtt ttccatagtt
     2101 ccctccaatt tcctatacta aatatattta gtatacttca tatacttaat atattcgata
     2161 tatctaatat actccaaatt gataagaatt cagactttat aaggaatata gtggatatac
     2221 taaatatatt tgctatattc agtatatcag atatattcaa aatgtcaaaa tatatttgtg
     2281 cgttttgcgt tgacaattta gagtgaaaag aggtaaactt aattctatag aaaccacaga
     2341 taattcacta tttacaaagt agcaaaagca gtggtactct ttaaacagaa aaattacata
     2401 aaaaaaagag acggaaataa ttgattttag cagaatcaat tatttctgaa tcacatggtt
     2461 aggacatgtg ttcacgctcg tctcaagaat atgtaagtag ctaccaacta cttatattaa
     2521 aagttgatcg gatacctttt ccgattgcct ttattctacc aaaaaaaggc gagcaactca
     2581 acagaagaac gtttatttag tgtacttaaa ttaaatattc ttaaacactg aagagagaac
     2641 acatactatg gctgagatta aagctaaact gtgttctctt tttgtttgag aaaggacgtt
     2701 acaatcgatg ttgagcgaaa tttattcagc tattcttaaa aacggcttac gtacatacaa
     2761 atatcgaaac agcaccatga aacctgcagg tcatattgat tccagtagga gtggtgctat
     2821 ctttgcgtac cgtagcaagc aattaatgaa tgttgggcgt ggtatggtca ttacttcgga
     2881 agaagctatt ttagagaacg aaaagaaact aacgcattgg acacctaata cctatcgctt
     2941 tggtacttat gcggatgatt atcgaacagt ggttaaaggt cattctgaga aaaacttaag
     3001 tcaaatcaac acatttgtag ttgatatcga ttcaaaagag aaccatcaag gcgaaattat
     3061 tttagcctgt ttagatcaag tgggctacat gccaacgcta attttagaat cagatcatgg
     3121 ttatcaagtt tattttgtac taaagacacc aggctatgtc acaaagaaaa gcaatttcaa
     3181 ggtgatcgat gtagcaaaaa aaatttcaaa aacaattcgt ctacagttgg ctgaaaaatt
     3241 gtccggagtg gatctaggat gtaaccactt cggaattgct cgattcccac aagaaaataa
     3301 tattgttttt aaagaaatga actatcagta ttcttttgct gactggattc aatggtcgat
     3361 gaagcttgaa tcagatcaaa aaacaaaaga agatcgagaa cgaaaactaa ttgtctttcc
     3421 tgagaaaaaa gaaattcgtc aagtagatga accgtggttc gatatgttac ttcataaagc
     3481 aaacatcgtc ggcggagaag gacgtcttgg tcgaaataat gtgattttca cgctttcttt
     3541 agcttattac tcttcaggtt atgcattgga tacttgcgaa tacaatatgt tcacattcaa
     3601 cgaacggtta caggaaccgc tatctgaagc agaattagta aagattgtac gtagtgctta
     3661 ttctggtaat tatcaagcag caagcagaga attcattatt gaattgtgcc agcaatgggt
     3721 ttcaccaacc ttaaaaaata atgatctgtt cattcaacga cgtggctggt ggaaatttaa
     3781 aaagccacga gatcaaagaa aatatagtca taaaaatgaa tggaaagaag atctattggc
     3841 ttatctaagc gaaaaaagtc ttgctagtga gccttatttg aacctgtcaa aaaaagaatt
     3901 ggcttcacaa ctaacgatgc ccaagcgaac acttgataag atcttaaatg agttacgaga
     3961 ggagaataaa gtcttctaca aggtaacacg aggaagaaat ggcggaatga tcattgcttc
     4021 agtcaaaacg ttgttcgcga gggttattca actaagtaaa gaaaagagac tagattattc
     4081 aacaaggatc acagaggtat ttggactcaa cgagagctta gtagaagaga catttagaca
     4141 attatcaacc cccttgaacc ctcttaaaga agtgaatctt tttgaagtag atacaggttg
     4201 aaaaataaaa ggtgcaaatt gccttataca atatatctat gatacttctg taggtgttgc
     4261 tccctttgcc tagctacgtg taggtggtat acttataact gcgtatgcag tcttatgtat
     4321 catggaggaa gttgtatgtc gttaaaaaat tatgtctatt cacatcctgt taatgtgttt
     4381 atcattggtc gtttgggatt atctgtggaa gtgttctgtg agctttatgg ttttaagcag
     4441 gggactttgt cttcttgggt taccagggaa aaaacagttg cttctttgcc gattgagttt
     4501 cttcatgggt tgtccttagc ttctggggag actatggatc aggtatatga ttgtttgtgt
     4561 gtgttagagc aggagtatat tgagtataaa atagctaacg agttaagaa
//
LOCUS       DARBDN010000148         4566 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000148 DARBDN010000000
VERSION     DARBDN010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.152"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..127
                     /locus_tag="SCH06_002696"
     CDS             <1..127
                     /locus_tag="SCH06_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEG1079213.1"
                     /translation="FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
     gene            209..1063
                     /locus_tag="SCH06_002697"
     CDS             209..1063
                     /locus_tag="SCH06_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEG1079214.1"
                     /translation="MENSLYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1160..3409
                     /locus_tag="SCH06_002698"
     CDS             1160..3409
                     /locus_tag="SCH06_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEG1079215.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3412..>4566
                     /locus_tag="SCH06_002699"
     CDS             3412..>4566
                     /locus_tag="SCH06_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1079216.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1603 a          649 c          836 g         1478 t
ORIGIN      
        1 tttcaactca cgttctgtta aagggctaga gagtagattt gaaagcatat tactggctta
       61 cagtgttcta ttaagtcgag cacaacgacg ttttgaagga actttgagat attctttagg
      121 atattaaaat taactagcac cacgggttat gtaataatat aaacataata aaacaaaaat
      181 tatccaaatc taacatagga gggtggatat ggaaaattct ctatatttag taacagaacc
      241 taacactcag ctgaaagatt gttactttaa tttttgtggg tattcaaaaa cagaacctag
      301 acatagtttt ggaccagcta ttcgagaaca atacttaata cacatagtgc tagaaggtga
      361 aggctattat tcaattaatg atcaaaaata ttttctgaag aaaggccaag gatttgttat
      421 cccaccagga gtatctactt tttatcaagc agatgaaaaa aatccgtggt catatgtatg
      481 gttgggttta agtggcaatc ttgtagaata ctatctaaaa gaaattggtg ttggaaagaa
      541 tcatcttacc tttaaagtcg aaaatttaaa ttcatttaaa ggattaattt ttgaaacttt
      601 atcgtatgat caggacaatc tagtcagtga attgtccaga caaaaacaag tttataaatt
      661 tttagaactc ctcttaaatt cagctagtta tctgaacgaa gggataatta ctaaaaagat
      721 gaatcctttt gttcgtcaaa caattgaaat aatacgtgag aatgcgtatc aaaaattatc
      781 tgttaaagat attgctgtca gtctatcgat acacgaaaat tatttatcac gattgtttaa
      841 gaatgatatg ggaatatcaa taaaagagta tattagtgaa atcaaaattt ctattgcaaa
      901 cgatctgtta tcatcaactg aatattcaat ccagcaaatc agtgacaaga taggattctc
      961 aacagtacaa tctttttcta aagcctttaa gaaagcaaat ggtgtttcac cgggagtata
     1021 tcgaaaacgt agattaggtc taggaatcat taatggtgaa taaactaaac atttgatttt
     1081 gataaatatt cgttacttta aacgcttact atttatgtga gcgtttttta taatgcaata
     1141 aagaaacgga ggagagctta tgtataagga taatgaaatg aatattattt atcgatcaga
     1201 aaaccaacaa tttcatttgt ttaatcagga gataagttac atttttaaga tatcggaaga
     1261 tggtaaatta ttgcatttat attatggtga gaacttacca gataatgact atagtcatct
     1321 aattgagatg catcatcggc ctatgacaac ctatagaaat gaaaacgatt tgctatattc
     1381 gttagagcac ttaaaacaag aatttcctga atatggtaca acagatttta gacatcctgc
     1441 tatttcatta ctacagaaaa atggctctcg cttatcagat tttgtctatc aagggtacga
     1501 agtggaagaa ggaaaaccta aactagaagg tttacctgct acctatgttg ataataatga
     1561 tgaaagcaaa acattgaaag tttatatttt agattcagtt acaaatgttc aagtagaatt
     1621 attatataca atttatagag attatcctgt tattactcgt agcgcgcgag ttatgaataa
     1681 aggaaaagat attcaaataa tcgagaatat tagcagttta tcattggatt tacccgatgc
     1741 aaattatgaa tggcaacaat tatctggtgc ttggggtaga gaaagaacta ttaagtcgcg
     1801 tactttacaa caaggaattc aatcaatcga atctactcga ggtatttcaa gccatcagca
     1861 taacccattt gttactttaa aaagaaaaaa tactgatgaa aatcaaggag aagctattgg
     1921 tgcagcacta gtttactcag gaaacttctt aattcaagca gaagtagata catgggatgt
     1981 tactagacta caagttggca tcaatccatt tggatttaat tggaaactca atccaggaga
     2041 aatatttaca gcaccagaag cgattctggt ttattcaagt aagggtttaa atgccatgag
     2101 tcaaactttt catcaactat ttagaaaacg cttagctcgt ggtaagtggc gagaaaaaga
     2161 ccgtcctgtc ttaattaata attgggaagc aacatatttt gattttgacg aagaaaagtt
     2221 ggtaaatatt gctaaaaaag catttgatgt tggtattgaa ttatttgtat tagatgatgg
     2281 ctggtttgga gaaagagaaa acgattgtgc aggattagga gattggcatg taaatcctaa
     2341 aagactacct agaggaatcg gcagcctttc agaaaaaatt cgtagttttg gtatgaaatt
     2401 tggtttatgg tttgaacctg aaatggtgaa taaggatagt gagttatatc gcacacatcc
     2461 gaattggatt atttctacac ctaatcgaaa acctaatcat ggtaggaacc aatatgtatt
     2521 aaattttggg ttagatgagg ttgttgaaaa tattttcgat caaatgtgta aaatcattga
     2581 tgaatcaaac ttagattaca ttaagtggga tatgaatcgt ccattgactg atgtatttga
     2641 cagtcacttg tcagcagatc aacaaggaga agtattccac agatatgtac taggcgtata
     2701 tcgcttatat gaaaaactta taacaaaata tcctaacata ctatttgagt cttgttcatc
     2761 aggtggtggg cgctttgatc ctggaatgct tcactatgca cctcaagctt gggctagtga
     2821 tgattcagat gcaattgaaa ggttaaaaat tcaatatgga actagtatgc tgtatcctct
     2881 ttcgtctatt ggtgctcatg tatcaattgt tccaaatcat caaacaaacc gtataacacc
     2941 tataaaaact agaggaaatg tagctttttt tggtgcattt ggatatgagc ttgacttaaa
     3001 tgaattaagt gaaggcgatt tgaggattgt aaaagaacaa attgcctttt ataaaaaata
     3061 tagaaccata attcataatg gtacttttta tagactatta tcaccattcg atgatgataa
     3121 tcaaaccgcg tggatggttg ttagtcatga taagaaaacg gctattgttg ctcattataa
     3181 aacattaaat gaggtaaatg ctccttaccg ccgactgaaa ttaaaagggt tagataatga
     3241 cggactttat aatgtaggac aaaatagttt gcgatctgga atggaattga tgagagcagg
     3301 actagtctgt tcagatgcat ctagtggaca aataaatgat cagaatcgac gcccagaaac
     3361 atttgatttt gattccaaga tttgggttat aacacaggag gaaaagtaga gatgaataac
     3421 caaaaaagct tacttcaaaa aggagcaatc ttaagtattt cactaatgtt aacaagctct
     3481 caagcaatta atggtgttat tccacaaatg aaacagtctt tggggatatc acaaagtcaa
     3541 agtgaacttt taggaactgc accaagtata actgttattt tgtttatctt attatctagt
     3601 tactttgcca aaagaatagg aatgaaaaag acaataattt taggtttatt attagctggt
     3661 ataggaggaa ttattccagt atttacagct accttccaaa ccgttcttat tagtcgagta
     3721 atattaggtg ccggtttagg agtatataat tcattggctg tgacatatat cagctcttta
     3781 tactctggca atactagagc aacgctatta ggtattagaa attcaatgga agctttaggt
     3841 cagacaatcc ttatttttct tgctggagtt ttagtgaaca ttaattggac ggcttcgttt
     3901 ttagtctatg caattgcgtt tcctgtagct ctcttattcg cgctaaaagt tcctgaaatt
     3961 agagatgaaa atagtgacat acctgaaaat catgtaaaag aaaagatgaa tccaatggtt
     4021 tttgccctag ttctatttgc aatcttactc gtaatgaata gtattgctat ttctgtacga
     4081 tttgcatcaa ttgcaactga aattaaaggg gtaaacttta atgctagtaa ctatttagct
     4141 ctaatgccta tcttaggaat actagcagga tttatgtttg gaccaataaa taagtggata
     4201 ggaaaaggaa ccctatactt gggaattata ttctttataa tttcaaattt gttaattgct
     4261 gtgtcaaacg gtaatatgac gttcctgcta acaggtttat ttttatcaag tataacagga
     4321 tcatggtgct tcccatttat ctttagtaac ttagataaag tcactacaaa gaatacaatt
     4381 aattttgcta cttcattgat ttttattggc tgtaatattg gtaattttat agctcctatt
     4441 gctatgcaat tagcacaatt tctaacaaga agtacaaatt tgactgctcc attttttgta
     4501 ttcgcaggaa tatttattgt gatcctattt gtaacatttt ttgcgacaaa taaaaaaaat
     4561 actaga
//
LOCUS       DARBDN010000149         4512 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000149 DARBDN010000000
VERSION     DARBDN010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.153"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..965)
                     /gene="lacD"
                     /locus_tag="SCH06_002700"
     CDS             complement(<1..965)
                     /gene="lacD"
                     /locus_tag="SCH06_002700"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEG1079217.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYV"
     gene            complement(962..1420)
                     /locus_tag="SCH06_002701"
     CDS             complement(962..1420)
                     /locus_tag="SCH06_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEG1079218.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(1417..2880)
                     /locus_tag="SCH06_002702"
     CDS             complement(1417..2880)
                     /locus_tag="SCH06_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEG1079219.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(2862..3794)
                     /gene="pfkB"
                     /locus_tag="SCH06_002703"
     CDS             complement(2862..3794)
                     /gene="pfkB"
                     /locus_tag="SCH06_002703"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEG1079220.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            3936..>4512
                     /locus_tag="SCH06_002704"
     CDS             3936..>4512
                     /locus_tag="SCH06_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEG1079221.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
BASE COUNT         1352 a         1015 c          723 g         1422 t
ORIGIN      
        1 acataaatag aagttgctgt ttcttctaat agtgtactta attctttaat attttgtttt
       61 ccttcttcta acatccaact actcgctttt tcttcgcctt cggtaacaaa aggtgctact
      121 cccttcgccc atgttgctcg cccacataag acaccattga atgtcgaacc tgattgtttt
      181 gcaaaacgca atgtatcttg aaatagtgca gcgctgactc ccgcacttaa aaaaataaac
      241 ggttgttcag tcactttcga ttgttcatag aaatacgcgg atgcctctgc ttgactataa
      301 caagtatctt gcccatatcc ttccacaaat ctcatattca ctggtacttc tactttcaat
      361 acatccactt gataacgttc ttttgaaaat tctcgcatgg cttcaatcac tttatgcggt
      421 tttacttttg catagtcaag agaagacgga tcgccaatag ttgcatcgta agaaaggagc
      481 tctaaaaaga aaggtatgcc ttctgcttcg cattctgaac caatccgttc tataactatt
      541 tgtttttgca cattaatctc tactggttca tcaacgtcat agtacaataa aaatttacaa
      601 gcatccgcac ccacttcttt taaccttttc actgaccaac tattcagtaa atctggtagt
      661 cggcctggca ttttcgcatc atagccggtt ttttcataag ctagcaacaa accacattct
      721 ttctctcgaa gcgctgctgc aggcagacca tattctggat cgagtaaaat agcggaagca
      781 tacggagtca ggtactgaga aaccatctgt ttaaattgga tgatatcttc tgatgtagct
      841 tctttatatt ggttgatcat tttcttcaaa gcaccacgtt ggtcgatagc tagcgcgcta
      901 ataattccag cttcatccgt caatcgcttc aaacgttcct gtttttctat actcattttc
      961 ttcatatatc ttcacctatt tctttagtta atattgtagc tatttctatt tttgattttg
     1021 cagctctcaa ctgttctgta acctcttttc gcatcaatga tcgtgcaacg agagacaata
     1081 atttcaaatg agtcgttcct gcttctgaat ctgggataaa taacgcaaaa ataaaatcaa
     1141 ctgactgtct atctaaactg ttccattcaa ttcctttttt cagtgtgacg ataatcaaac
     1201 taggttcatt gattgtttga gacttcgcat gagggatagc aaaacctgac attattcctg
     1261 tagtaccttc tttttctctt tccagaagtt tttgatatac ttctttttcg tcatgagcga
     1321 ttcctaaaca gaatgtttgc tttgctaaaa acttaaatgc ttcttcttga ttatctaatg
     1381 gctgttgtaa aaaaatgttc tcttcatgaa tgattgtcat gataaacctc ctgctcttcc
     1441 ttcttcgata actgtacgat ttgttgcttt attatccctc ttcttgtctt tatcagttac
     1501 tcttttcttt tggatcaaac ctagtatcac tccaccaacg atcgaaccaa taagaatcgc
     1561 tgtaacccat tggatttttc ccgtcactac aggtaacact aaaaaaccgc catgtggggc
     1621 tggtacttgg acaccaaaca gataggtcaa gacagcagca attgatgagc ctaacatcat
     1681 cgttggtaat actcggatcg ggtctttcgc agcaaacgga atagctcctt ccgtaatatg
     1741 agttgatcct aaaataaaat taaccaaacc tgcattacga tcattagtat caaaatattt
     1801 accaaacaat aaagtagcaa aaccagtaat caacggtggt gcaatgcaag ctgctgacgc
     1861 accagccata aaagtcgtgt ttccttgtgt caaaagagct gttcctgtta catatgccgc
     1921 cttattaacc ggtcctccca tatcaaacgc acacatacag ccaacaatca cgccaagaac
     1981 aagtggattc gaatattcaa atccagctaa aaagctcatc attccttcat ttatagcctt
     2041 cattggacct gccagcaaag acatcacgat gccaataaat gctacaccaa taactggata
     2101 taagacgatt gccttcaagc catctagttg tttaggtaaa attatcagta gcttttgcaa
     2161 aaataagata aaataacctg ctaagaaccc agctaaaata cctcctaaaa atccagtacc
     2221 gccattcatg gctacgattc caccaacaaa tccaacgact aaccctggac gtttcgcgat
     2281 cccttctgca atataagctg ctaaaactgg aaccatcatt cccattgctg catcgtcaac
     2341 tgcttttacc attgccgctg tagcattgta ttgtgcatga tctggatcag aagaatagat
     2401 tccccaaacg gcaaatgaaa tagcaatcaa tactccgcca gctaccacga aaggcaacat
     2461 atgagagaca ccgttcatca aatttttata gatgctacga ccaaaattag caccacttat
     2521 cgcttctggt tctaaagtat cagcagcttc attatctgct aagacagtac cttttcctgc
     2581 caatgcttcg tcaatcagcc gttgtgcatc cttgattcct gtactgacag aaacatcaat
     2641 gactcgtttt cccacaaatc tttctgaatg gacatctttg tctgcggcaa taatgacagc
     2701 atctgcctgt ttgatttctt cagccgttaa ttcattctcg atcccaattt gtccatgggt
     2761 ctccactttg atcgtgatgc cttttttcct agctgcttgc tctaatgcct cttgcgccat
     2821 gtaggtgtgc gcaattcctg tcggacaacc ggttgctgca attagttgat attttcccat
     2881 ctttcgaacc tctcttcctt gattttgatt tgtttactta attcctccac atccaaaaaa
     2941 tcagtcagtc ctttacgaaa agcagtagag ctgcctgctg ctatgctttt acgtaacgtt
     3001 tcatcaagcg atcgtcgatt catgtatcct gctaaaaaag tgcctaacat ggcatcacct
     3061 gcacatgctg tattgacaac ttttcctttt ggcgagtttc ctcgaatcac cctgtctttc
     3121 gtaaaaagaa tcgctccttt ctcaccgagg gataacaaaa cattttctgc gcctgactct
     3181 actagtcgtt gtccataaac aaagtaatct tcatctgtaa ccatttttcg tccgaaccaa
     3241 gaagaaagtt cttcctcatt tggtttcagc aaaaacggtc gatagggtaa acaatccatg
     3301 acttcttgat cactactatc aataatcaaa caaatccgac tgatttctat taaaaccttt
     3361 ggagacagcc ctcttggtaa actcccagaa acacaaagat aatcccctgc ttgtaatgct
     3421 cttatttgat ttaaaaaatt atgaacagct gtctgcggta tttcaggtcc ttgattcact
     3481 aatttgtatt cttctcccgt ttgattgact tgtgtaaata cattgatacg cgtcatacca
     3541 ggcacttcaa taaactctgt ttggatttgt ttctgctgta aatagtcttc tatatacttt
     3601 cctgtgaacc cagcagaaaa acctaatgcc gtacttggga aatctagcat ctttaatact
     3661 agtgacacat tcaccccttt tccgtttgcc tgaatgtcat cctcttttgt gcggtttacc
     3721 ataaaaggat gcatctcatc tgtttcaata aatagatcaa ttgccaaatt catcgtgcat
     3781 gtgtagatag acataaccaa cgacctcctt gattctatta tgaaatacgc gaaatagaaa
     3841 atgttttctt aatcgtccca acacaaagaa aacctttaca tttataaact cgtcgtgctt
     3901 tttttaacta acttttggtg aaagaaggaa agaatatgaa tcacaaatta agtgaaacag
     3961 agcagtacct ctggaacttt atcgaacacc tcatcctaga gatccctaac tattccatcg
     4021 tgaaactaag tgaacaagca aatgtctcaa cagccaccat tgtgcggaca atgaaaaaga
     4081 aaggctatga agggtttact tcgtttaagc atcatctaaa agaaggagaa aacaagaaca
     4141 tcaatttttc atttttagat aaagtagaca aaggaatccg ccgagccatt ctaaaaaatg
     4201 aacaagaagt ggtacgtaca atcaatatgt tggaaatcgg gaacattgaa gatgcaatac
     4261 aaagaatcaa atttgctgac cgggtttttg tctttgcccg aggattttca gaaatgattg
     4321 gccaagaaat gctggtaaaa cttcaattaa cgggaaaaaa ttgtcagatg catactgatc
     4381 cagaaattat caaaagcatc agtcggaaac taactaagaa agacagcgtt atttttgttt
     4441 ctttgaacgg tgagaaaaca aataaaaaca tcaaaaataa gatttatgtc tttatttttc
     4501 aattttttaa at
//
LOCUS       DARBDN010000150         4475 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000150 DARBDN010000000
VERSION     DARBDN010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.154"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            323..1054
                     /locus_tag="SCH06_002705"
     CDS             323..1054
                     /locus_tag="SCH06_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEG1079222.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1199..3226
                     /locus_tag="SCH06_002706"
     CDS             1199..3226
                     /locus_tag="SCH06_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEG1079223.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3334..4431
                     /locus_tag="SCH06_002707"
     CDS             3334..4431
                     /locus_tag="SCH06_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEG1079224.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1574 a          717 c          923 g         1261 t
ORIGIN      
        1 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
       61 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
      121 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
      181 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
      241 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
      301 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
      361 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
      421 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
      481 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
      541 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
      601 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
      661 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
      721 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
      781 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
      841 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
      901 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
      961 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
     1021 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
     1081 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
     1141 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
     1201 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
     1261 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
     1321 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
     1381 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
     1441 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
     1501 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
     1561 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
     1621 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
     1681 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
     1741 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
     1801 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
     1861 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
     1921 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
     1981 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
     2041 gcaaagaagt cttacttatg atttggaagg tgtcggtcac tcttctcgga ttatacctga
     2101 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
     2161 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
     2221 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
     2281 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
     2341 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
     2401 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
     2461 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
     2521 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
     2581 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
     2641 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
     2701 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
     2761 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
     2821 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
     2881 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
     2941 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
     3001 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
     3061 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
     3121 tacagctcat cgtggaatca gaatagatat tcctgtagaa aaccaaagaa tcggaacctt
     3181 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
     3241 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
     3301 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
     3361 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
     3421 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
     3481 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
     3541 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
     3601 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
     3661 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
     3721 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
     3781 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
     3841 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
     3901 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
     3961 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
     4021 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
     4081 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
     4141 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
     4201 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
     4261 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
     4321 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
     4381 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
     4441 aacaaatagt aaatttttat tattgtagga tggtt
//
LOCUS       DARBDN010000151         4408 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000151 DARBDN010000000
VERSION     DARBDN010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.155"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..338)
                     /locus_tag="SCH06_002708"
     CDS             complement(<1..338)
                     /locus_tag="SCH06_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079225.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEF"
     gene            complement(546..1472)
                     /gene="glsA"
                     /locus_tag="SCH06_002709"
     CDS             complement(546..1472)
                     /gene="glsA"
                     /locus_tag="SCH06_002709"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HEG1079226.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(1495..2922)
                     /locus_tag="SCH06_002710"
     CDS             complement(1495..2922)
                     /locus_tag="SCH06_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1079227.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(2953..4167)
                     /locus_tag="SCH06_002711"
     CDS             complement(2953..4167)
                     /locus_tag="SCH06_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEG1079228.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1388 a          929 c          778 g         1313 t
ORIGIN      
        1 ataaattcaa gatcagccag ttctgtactc gtgaatatac cattaaaata ataacttaaa
       61 aactttaaaa aataagattg accgtacaga aactgtgtga gctcagaaag agcaatacca
      121 tgtttgaata cgagtttata cttatgcttc tctcttactt gttcttttat acaatattct
      181 agacactcgg ctagactttc tagatcgtga aggatcgttg gtgtagtcac ccttagagaa
      241 atagctgttt gttcgatgtc tatttcttgg aattcaaata attgttcaca cagatacact
      301 tttctaaata tatttcgctc gatgtaattt tccagcattc ctgatacacg cctccagttt
      361 ttcttatgat tttatttaat catatctgta aatcgtattt ttgtttcctt tttatttaga
      421 aaagcccttt caaaaaccaa taaaaaaaga aactgggaca aaagtcaaac aagctcacaa
      481 tttcagcctc attgtaggta gctttgagcc gtttggactt ttaccccagc ctctttcaag
      541 aatggttatt caaagatgtc agcgtctagt tctttgacta catctttcaa caattggata
      601 ccagctgcgc tgttaccaaa tggatctagt gccgggctga agacacctat gccgtaacga
      661 tttggcacag ctgccatcaa cccgccgcct acaccgcttt ttgcaggtac accaacatgg
      721 acggaaaact ctcctgattc atcatacaaa ccagcagttg tcataattga tttgacgatt
      781 gtagcacttt cttcagtaat gatttgtttg ccattccaag gagcaattcc tttatttgcc
      841 agcacagcag ctaattttgc tatgcctgta gcggtgacat tgagggagca ttgtctgaaa
      901 taagcatcga gtatctccgg tacgtctcct tcgatcattt gattaccttt catatagtaa
      961 gcaagagagc gattgatatc acctgttctt gattcagaat gatagatttc ttcattcaat
     1021 gtgatattag gatcatcaca gatctctttc ataaatgaca agattcgctc aaatttttca
     1081 tctgcatctt taccggcaat caacgaggtt gttgcaatcg ctcctgcatt aacaaaagga
     1141 ttcattggat gtttgcgatg attgatttcc atattcatga tagaattgaa ggcaaaaccg
     1201 gttggttccg tgttgattgt ttgaaagact ttttctattc cgttgtcttt gattgctaat
     1261 aacaatacgg gaacttttga catgctttcg atggcaaagc gcacatcggc gtctcctccc
     1321 tcaatcagtt gttttgtatc caaatcataa atcgccatac ctaattgttt gggatccact
     1381 tcagctaatg ctggaatgta atccgccact tgtcctgttt gataatagtg gaaatttttt
     1441 ccaatcaatt gttctaattc ttttacttcc atttgaataa ccagctttca ttttttattt
     1501 ttctgcatgc tggaatttat gacggcatgc gtagatcgta aatggaataa ctaagacgat
     1561 aagataagaa acaatcagaa tcgtttcata aatcccatgc tgtccagctg cgatactagc
     1621 aggtggaaca aatgagatac aaaaagcaaa aagtgaagtc aaaagaccta aacaagcaac
     1681 gattactttt acaacttttc cgcctggaac ctgataggct ctttcaagac tgtcatcttt
     1741 aaaaaccagc ttcaaatagc ccgcgaaaaa cataaagtac aacatcaggt agattacaac
     1801 agtcaatgac atcgctgcaa gaaatgaaag attattcccc ccgccgctta atgtaaagac
     1861 ggctgcccag attgttgcaa cgatcccatt tgcgatcatc aaatgagcag gaacaccgtg
     1921 tgtgttttct tttgcaaaat attcaggaag taatccttct tctgctgcta cgtgaagtgc
     1981 ttttgaagga gaggttaccc aagaagcaat ttctccgatg acacctaaac aaacaagaat
     2041 cgcaagaatt ttcgcaatcc atgcaagatt tggatcaatg tgtcttaata ggaattctaa
     2101 cgattgaatc acccctgtat taagagacaa accatgttga ggtactgtag tagcgacggt
     2161 caatccgcca aaagtatcta aaatgattgc cagaataacc aatacaaaca ttgctaatgg
     2221 ataatccttt ttagggtttt ccatttcatt tgcatgactg gcagatgttt ctacgcccat
     2281 atatgctaaa ataaaggaaa caaaaacaac cagcgtaggc aatttcgaaa aatcaggaat
     2341 caatgttttc atagacagta tcgtttgtag tggagcgcct gaagcgacat aatggatccc
     2401 taagccaaac aagactaatg ctggcaacaa gataccagct acaaaaccga tccgagcaat
     2461 caatgaagtg tatttggttc cttttaactg tgagagtaaa atagcccaga aaataatcaa
     2521 taggattgcc aatttcagat atttattgtt ttgtatagca ccaatacccg ttgcatagga
     2581 taatgcacca gttaagaaat acagcatggt caagtagcca actgttatct caaaccattg
     2641 gaaaaagatt gcggcaaaac cgaatcgttt tcccaatgtg cgactgaccc aagtatagac
     2701 accgcctttt tcccatcctt tcaccgttgc catctctgct gcgcacaatg ccacagggat
     2761 aaaccatagc aaaccgccta ataacaagaa aaatactaag ctgaagcctg aggtcgcgaa
     2821 tgtgggatat tcatataatg aaacgaccat tgagatggtc atagccaaaa agccaaagaa
     2881 cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc atgaatcttc ctcttttcta
     2941 tttgaatttg tttcaattga gtttgttgcc aaagaagaaa aagtccaatc cttcttcttg
     3001 ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc gattttaaaa tcactgttgt
     3061 cagcacatag gcatacacgg cagtaatgat gacaccaatc acttgaatcc ctaagaagta
     3121 ccagctgctt ggattcgtta gtaaatggct gttagatgca aagatcccta tcagaatcgt
     3181 acctgtgaat ccgcccatgc catgaacacc ccacacatca agtgcatcat cccattgttt
     3241 ctttttacga aaatcaacag cagcatgaca gacgataccc gcaatgatcc caatcagcat
     3301 ggcacttttt gcttctacat aaccggcaca aggcgtaatg gctgccaatc cagcaacgga
     3361 tcctgttagt acgtcgacaa aatcaaagcc atttcctttt acttttgcaa tgatcagcca
     3421 agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca aatgcattga ctgcttgttc
     3481 atctgctcga agtgcaccac cggaattaaa accgaaccag ccaaaccaaa gcagtcctgt
     3541 accgatagca gctgccataa gactgctatg ctgacttctt tctcctaaag gaatctttct
     3601 ttgaccaagt gtgaggatac atgctaaaga gccgaatcca gctgtcgtgt ggatgactgc
     3661 tccaccagcg aaatctctaa atcccatctg atccaaaaat ccgccacccc atatccagtg
     3721 gcaaacaggg aaataaatca gcagattcca aaaaataaca agtataatat agccttttaa
     3781 attcaatctc cctgcaaaag ctcctgtcat caaaggaacg gtaatcacga taaacatcag
     3841 ttggtaaaga aagaacatta aaaatggaat cgttgcacca tgaaacatgt tggggaagct
     3901 tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca ataacaccgc cgatatcccg
     3961 tccaaaggcc aatccgaatc caccaaatac ccacataatc gttgttatcc caacggagag
     4021 aaaagattga gacatgatcg ttagtatatt attcttccgt gctaatccgc cgtaaaaaaa
     4081 agctagacca ggagtcatca ggcaaaccat tgctgtacat aaaatcatga atgctgtatc
     4141 tcctgtattg ataggtaatg tattcatttt tttcgcctcc tttctacgat tacgagtata
     4201 aaagaaggtg tagttgtttt tttcttctgt ttttttgaat taatacttgc atttataaaa
     4261 gacagacaat taataaaagc ttgatgtgtt gtgctctttt tcgtttttca cacaaataaa
     4321 gacaaaaaat aaacggtctt ctttttatag aaaaccgttt attttcgtct ttttttattt
     4381 ttaaagatat tttttcataa ggaataaa
//
LOCUS       DARBDN010000152         4345 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000152 DARBDN010000000
VERSION     DARBDN010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.156"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(387..1853)
                     /locus_tag="SCH06_002712"
     CDS             complement(387..1853)
                     /locus_tag="SCH06_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1079229.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKKITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="SCH06_002713"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="SCH06_002713"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEG1079230.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
BASE COUNT         1309 a          927 c          697 g         1412 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tttttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacataact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaa
//
LOCUS       DARBDN010000153         4324 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000153 DARBDN010000000
VERSION     DARBDN010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.158"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..281)
                     /locus_tag="SCH06_002714"
     CDS             complement(<1..281)
                     /locus_tag="SCH06_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEG1079231.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLKYQSLTLPLKMQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMRLNEGNGYLRSVSNNGWQLLDQHEEN"
     gene            complement(730..2138)
                     /locus_tag="SCH06_002715"
                     /pseudo
     CDS             complement(730..2138)
                     /locus_tag="SCH06_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
     gene            complement(2359..2721)
                     /locus_tag="SCH06_002716"
     CDS             complement(2359..2721)
                     /locus_tag="SCH06_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079232.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(2725..3063)
                     /locus_tag="SCH06_002717"
     CDS             complement(2725..3063)
                     /locus_tag="SCH06_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079233.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3042..3461)
                     /locus_tag="SCH06_002718"
     CDS             complement(3042..3461)
                     /locus_tag="SCH06_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079234.1"
                     /translation="MTDLSEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQLTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(3454..3687)
                     /locus_tag="SCH06_002719"
     CDS             complement(3454..3687)
                     /locus_tag="SCH06_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079235.1"
                     /translation="MTEKQKYFGKKNWLVNLTGDYVVVVFLDSKKMSGKLLDVTQYEL
                     ILKNNKIDSPIIIPKHAVKYIYAVAESSGEAND"
     gene            complement(3684..>4324)
                     /locus_tag="SCH06_002720"
     CDS             complement(3684..>4324)
                     /locus_tag="SCH06_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEG1079236.1"
                     /translation="PNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQ
                     YRVVDPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPPEITTWWR
                     LELQLRRGKATDWHEMVHESLDSFASPHYFPPNTKVTERIMVKGLLYDHSEWGNLAKN
                     TKKKYRDLLKQESQNDELTNHLRETFAESADDLKKELDTWLLGLDVTEEEEK"
BASE COUNT         1223 a          961 c          620 g         1520 t
ORIGIN      
        1 atattctctt catgttggtc taacaactgc caaccattat tactaacaga tcttaaataa
       61 ccattacctt catttaggcg cataagctgt tcaaaattta aaatcaacac atcatttgga
      121 gtgtgataat aaatattttc tttcagtttt ccgactatgg taattcggtc aattgaccac
      181 tgcattttta agggaagggt caaactttga tactttaacc gcctgttaga gggggctgtt
      241 aatttttccc actcatttat gatcgtgcct tttttactca aattttgttc ctcctcaaag
      301 aaaaagagac ttctggaaag aattttcaaa agttcacgta actcttaaaa attcattacc
      361 aaaaaatctc tagtcttgaa gaaatctaaa aatattcgta taatgattaa gaagttacgg
      421 agctagtgcg attagtttcc gtaaaggtcg agaacgtgtc cagcgttgct cgactttatt
      481 tttttgctct tttttcagtt tatttatttg ataactcaat aatagcactt ctctttagct
      541 atgcaaatat ccaaaaaata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta
      601 acgctaggtt ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt
      661 agtggtttag ccgtcaactc cttatcctcg gcacaaaccg cctccggtac cgttgactgc
      721 acatcgtaac taccactcga tctcatcttc agaacgctct aatttacgct gtgagacgtt
      781 ttgacgataa aataaggttt tctcctgctc taacacttct aattcctcag aaagccccat
      841 atccttttct gcaagaccaa aacggataga caaacgagtg atcgattttt gaaatgcgtt
      901 ttttaatcgc tctaaacgct ggcgtaaaga gcgattttct tctttcagct ttttattttc
      961 cacttgtaaa tctgctaatt gttttctacc agacaaatga cgctcttctt ccaatgtagc
     1021 tacatactca tttaattctg tattttgctc aagcatctgt aaatattgct cactcatgtt
     1081 atcagcattt ctcttggcat ttgttgctct cgtagctcgt tgatacaaat caacaaaatc
     1141 attcccagat aaatgatacg aaccatcagg aagcctcttg aaactttcta aaggaacaat
     1201 atctttttgg aaaatgaccg ccatctcttt ttttacattc agcatatttt tcttctcttc
     1261 ttcaatcttc actctctcag aagccaccag agccttttct cgctcatttt cttctctttg
     1321 cctagaaaaa tatacctcaa ctcatcagaa acgctctcac gctcttttac ggccgtttga
     1381 cgcaattctg aaatctcgct catgatttct ttatattcgt gaacatcttt gattttgtta
     1441 gtaccgacta actcacgctc ccaaccaaaa tctgccatca aacgttcaat tgactcaact
     1501 tcctgattcc taaaattatt ccaaatcact cgaccattct ctttatctgc tcgtaaaccc
     1561 tgctgttgca aggctttgtt aaaacttggt tgcttttgaa caccccgttt atacccttca
     1621 gcaacaggaa caatattcaa atgcaggtgc ggacttactt cgtcattatg aataacagca
     1681 ttgtagacgg ataaattagg attccgttct ttaaattctt tgaaatattc aactaaaatt
     1741 ttgttggcaa tcactcgatt ttgttctgct tgttgttccg atatgccagt agaagaacca
     1801 tcatcacgag tagtacgaaa atcatcaaga gtaccaattt gcacgataaa ttctcgctgt
     1861 ggttccaatt ttttatcctt gcgaaccttt gctaaatagt cctcgatttt tctatcggct
     1921 cttttctgct ttgcattata tttttctacg gcttcaccga ataattcttc atatttttca
     1981 cgaatatttg tttgttctaa atagatattt tcatccgatt ttgtgaaatc aatatgctta
     2041 tgccagtcat tgattttttg gctatcagtt aactcacgat tattatgaga aatgcttgta
     2101 ttctttgttc cctttttgaa cgaaatactg aaccccaagt taaaaccctc cttcggctgt
     2161 cgctaataaa aagagtgtaa acctttctgt tactctttgt caaagagtaa cattttccta
     2221 attgtgacat ggctgtcaca attccaaatg ctctccgagg gtattcgctg tcacaagtga
     2281 caacgaaaaa aggagccgaa agcgtgtcac gctctcaact ccttttacgc tttattttgc
     2341 ttcacgcaaa ataatcgctt atcgtaaatt cacgtcatta aatattgacg taaatttact
     2401 ctcactcatc tgacttttct tattcggtat cactccgaat aagccgtcag attcatcggg
     2461 ataatctcgt tcgcttggcg ctgatttttc atcagcaagc cactcattat ccactgattt
     2521 ttcgtgttgc tgatcgtcag aaatcgacga tagccaccgc tcaaaatcag caaaagtttc
     2581 aaacccaaaa cgcttccgaa gagccttgcc cattgcagca ttttctttct caatcaagcg
     2641 ttttttctgt tggcgaagtt tcgcttgttc tttttttaat ttttcttctt gcgctttaat
     2701 atctgctaaa gtcattccca taaactacat ctccttttct ttggaattaa taacggaaat
     2761 ttggtttaac tgcataacat gactcattaa tttcaaccaa aattcttttt ctgattcatc
     2821 agttgtttgc gctaaatgct tatgaacaaa ttcattagtc aaaactgaag attttgctaa
     2881 atcagcattg ataaccgagt tgagaacatc cataattcgt tcaagcattt cactataatt
     2941 atcttcatcc ggcaaattca aataatcagc taaccgttca tacatcaatt caattctatc
     3001 gactgtttct tctctcaaat caattttatc catgtcacac ctcacttcca gaattgccac
     3061 cattttcgat tttttaattc ttgattttct agtaacaact gatcgttttt ttgttgctga
     3121 agcagggtca atttttgttg atcacgaatc atttctgtta attcagaaat atgtttgtcc
     3181 ttctcagcta attgatcacg caaaaactca ttctcttttt ctaaaggaaa atcactgcct
     3241 gtgttattga ccggtaattg accagtcaat tgatcacttt ttgaccgata aattgaccga
     3301 acaacaccaa tcaactcttt atctagcatg ataatgccat tttctttata ctgagcaagg
     3361 tcaaaccctg aattgaccag ttgattgcgc actgtatttt tcgatacacc caattcgtca
     3421 gcaagatttt ttatggtcat cttttctgac aaatcagtca ttagcttctc cactactttc
     3481 agctaccgca taaatatatt taacggcgtg cttagggata ataatcggag agtcaatttt
     3541 attatttttc aaaatcaatt catattgcgt tacatcaagt aacttaccgg acattttttt
     3601 gctatccaaa aaaacaacca caacgtaatc acctgttaaa tttaccaacc aatttttctt
     3661 accaaaatac ttttgttttt ctgtcatttt tcttcctcct ctgttacgtc tagccctaga
     3721 agccatgtgt ctaattcttt ttttaaatcg tctgccgatt ccgcaaaggt ttctcgcaaa
     3781 tgattcgtca attcatcatt ttgactttct tgcttcaaca aatccctgta ttttttcttt
     3841 gtattcttag ctagatttcc ccactcagaa tgatcataaa gcaaaccttt caccataatc
     3901 cgttcagtaa ctttagtatt tggcggaaaa taatgtggac tagcaaagct atccaaactt
     3961 tcatgaacca tctcatgcca atcagttgct tttccccttc gtaactgcaa ttctagtcgc
     4021 caccatgtcg ttatttccgg cggaacaatt ttacgttttc tttcttgttc cagtttttta
     4081 ttatacatcc gaatttgtcg ttcactggca cgactacccc aatatgccgt ttctaactta
     4141 ccagaacgcc cataaattgg tttaaaagac acaggatcaa ctacccgata ttgtgtaata
     4201 aactcatcag gtacatcgat aatgtcgcaa gcaatatccg cacgtgaaaa gtgaggttcg
     4261 ataaacaaat catgaataaa atttttcatg gaactagcta agaattgact aatcttattc
     4321 ggat
//
LOCUS       DARBDN010000154         4310 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000154 DARBDN010000000
VERSION     DARBDN010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.159"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(65..1285)
                     /locus_tag="SCH06_002721"
     CDS             complement(65..1285)
                     /locus_tag="SCH06_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HEG1079237.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="SCH06_002722"
     CDS             complement(1305..1916)
                     /locus_tag="SCH06_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEG1079238.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="SCH06_002723"
     CDS             complement(1959..2891)
                     /locus_tag="SCH06_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEG1079239.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="SCH06_002724"
     CDS             complement(3312..4172)
                     /locus_tag="SCH06_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1079240.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DARBDN010000155         4153 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000155 DARBDN010000000
VERSION     DARBDN010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.160"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..106
                     /locus_tag="SCH06_002725"
     CDS             <1..106
                     /locus_tag="SCH06_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079241.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(359..508)
                     /locus_tag="SCH06_002726"
     CDS             complement(359..508)
                     /locus_tag="SCH06_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079242.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            970..1182
                     /locus_tag="SCH06_002727"
     CDS             970..1182
                     /locus_tag="SCH06_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079243.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1460..3259)
                     /locus_tag="SCH06_002728"
     CDS             complement(1460..3259)
                     /locus_tag="SCH06_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEG1079244.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3383..3979)
                     /locus_tag="SCH06_002729"
     CDS             complement(3383..3979)
                     /locus_tag="SCH06_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEG1079245.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1490 a          728 c          707 g         1228 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaaaac gcatatacct gcggtggcag gttatgcgtt ttttgttgta taaagacttt
     1441 tttcattaac gatttttgat tagccgactc ccaaaacaaa atttagcagt ttatctgaat
     1501 aagtgatttc ttcatctgtt tgtttcacac tttcatttag tagtcccatc tcatcggtta
     1561 tgataccatc cacaccataa aacatcatgc gactcatagc atctgaatcg ttgattgtcc
     1621 atacatatac ttcttttccg tcttggtggg cagaattaat gaagttacgg ttgatcgtac
     1681 tatattccat tgtcagaaaa tcagcaggcg tcacaggggg cccaacaata ttgaaaggta
     1741 agatgtagcc cacataaaag tttggttctg cttcttttaa atctgaaacg gtttggtacg
     1801 tcaaactttg caaaatatga tggttctcta agataacttt gcggtattta tggacaaatc
     1861 gttcgacaag gtcatccgaa tcttttttag aggtcttgat ctcaataagt aatttttggt
     1921 ttagcttatg tgctttttcc aaataagaat caaaagaaca aacaggggct tgcactccgt
     1981 tttcagtaac tgtaagattt gtcaattctt tcaatgtaag atcctgtggt gttccattta
     2041 cccctgttaa gtgacgaaga tttgcatcat gcatcactac gaaatgacca tcttttgttt
     2101 cctgaacatc catctctaca taatcaggat gatagtctct gcttgttttt tcaagtgctt
     2161 ctaaagtatt ttgcgcccca ttttgggtac tcacacctct gtgagagaca gtcactggtt
     2221 ttgtctgaac agctgaagtc agataatcca tattgtaaag acagacgcca ataccgaaaa
     2281 aaactgcaaa aagagtcaaa ccagtgtttt tcagcgcaga gaaacgcaag ttgggggctt
     2341 gtgggataaa ccacttaggg atctcaggca agaagccttc gtcatccatg aaatcaacaa
     2401 tgatataaaa aatccctacg gtagacatca cgatattgaa taataaaatc ccttgtaaaa
     2461 gcgtcatagc aaacacagcg ctgatcaatg catagtctgg gaaaaattgt tcaaccatac
     2521 tttgtgccaa aataacaacg atatatccta aagaagaaag gagtaaaatc gtaccgccaa
     2581 tcacaataaa ttggcccgtg atggccaaaa gacgcgattt ggtcaatgac cagctttccc
     2641 gaatggctgc tcgaaaagga cgatctcgta gaatcatttc cggtaaagca aaaatcagtc
     2701 gaatcccaat atagccaagg aaaatataaa cgagtaaaaa ggaactgacg atgatccaac
     2761 gattagcaaa aataaaatcc ataatgaaag cggggatttt tatttttgac agtagatcag
     2821 aattaaaact taatccgctg atcggtagaa tcaataaaaa ataagcaagg aaaaacaaaa
     2881 aagtaatggg tctcactttc ttcagctgaa gtatcgtcaa gtgtaagagt tgcttcaaag
     2941 agattggttc tttcttttta ataaaaaaaa cactcatcaa aagaaaagta aattcgaaat
     3001 aaactaacag taaaatcgtc atcaaaacta cgattaacga gagtagaacc ccaggatgtt
     3061 gagaaaaaat tgaaggaata ttgtcataag acaaatagtc aattgcccct cggtgtaaaa
     3121 taaaacgggt cgtactgctc aataagggta aacaaataaa taaaataaag ccatgcatca
     3181 gcaagacatc acggaaataa gcttgtgttc cttttaaaaa gtcccaagca ttacctaagc
     3241 tacgtttcaa ataattcatc ctatcacctg ctcttcacat tgtagcgcaa atctaatgaa
     3301 aaaggaaagg gtgcagtgtg ttttgcagac cctttcccag atttaacatt gtcaatcaat
     3361 gactaatttt acaaaataaa tattatccaa gaagaccact tagatattga cctccataaa
     3421 tcaaggccat actatataag aaaatcgaca gtggtttagc aatcaaaatg attagtgtat
     3481 atcgtttcac tgacatgttt gtcaatccag ccatcaaaca taacgcatcg tcaggagcaa
     3541 ctggaagaaa aatagctaga gcaaacagct tctcaaaacg gttttgatta tccagccagc
     3601 caatatattt gttatatgtc ttatcgctaa tcatggaaag tatgaatggc tttccataac
     3661 gacgccctag cagaaaaatg ataatcgaac caatgcagat tccaatatag ttatagataa
     3721 atccagcata agggccaaat atcaggacac cagctgcagt actgatccct ccaggaatga
     3781 ttggaataac tacttgcagg atttggatga agacaaaaat aatcggtcct aaaatgatgg
     3841 aatcacctac taatcctctt aacgcattca aatctttgaa aacacctaaa ttaataaaat
     3901 aaatcgtcag cgcgattgat aggcctaatc cgataatgga tatgaaattt atcagttttc
     3961 gagaggcagc aatattcatt attcatcaac tccttagagg ttctttgtta actatacttt
     4021 actagaaaag caactaactg cgccattttt tgatatgaca gaaaacaaac aattttgtaa
     4081 gttcatcata agtataaaag attgatctca aaaaaacatc caactaaaga cttatttaat
     4141 aacttgtttt ttt
//
LOCUS       DARBDN010000156         4131 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000156 DARBDN010000000
VERSION     DARBDN010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.161"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(130..216)
                     /locus_tag="SCH06_002730"
     CDS             complement(130..216)
                     /locus_tag="SCH06_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEG1079246.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            892..1842
                     /locus_tag="SCH06_002731"
     CDS             892..1842
                     /locus_tag="SCH06_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HEG1079247.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            1863..2396
                     /locus_tag="SCH06_002732"
     CDS             1863..2396
                     /locus_tag="SCH06_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEG1079248.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            2412..2582
                     /locus_tag="SCH06_002733"
     CDS             2412..2582
                     /locus_tag="SCH06_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079249.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            3032..3565
                     /locus_tag="SCH06_002734"
     CDS             3032..3565
                     /locus_tag="SCH06_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079250.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            3577..3780
                     /locus_tag="SCH06_002735"
     CDS             3577..3780
                     /locus_tag="SCH06_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079251.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKSKKK"
BASE COUNT         1474 a          681 c          763 g         1213 t
ORIGIN      
        1 caaaattgaa tttgattagc aatcatgtta aactgaacct gcaaatgatc aaacattaga
       61 tacacgaaag ccccagagag gtcggattct ctggggcttt ttttcaggtt gatgtcgcct
      121 ttattgattt tacttcttgt ttcggttatt caaccaataa ctgaataaag agacacaaac
      181 ttctacaaga agggggcaaa tgaaccgttc aaacattaga tacacctcct tccagtcgca
      241 agactgtcgg ataggcgaca agttattata ccttacaaaa taaaatctgt gtggtgtttt
      301 taagtatccc ttattttcgg gttgttaggg cttgccctga ccgcctgtaa ggcgctttaa
      361 gaacaagata aggtttttta cccaagactg tcttaaaacg acttagacga gctatcagag
      421 gcttccccca cctccgttac tgacttgttt ttagcaaagg agcctttagg cgactgcgca
      481 gtacaatgtg agagcatagc gatcacactt ttttagcgac cgtagggagc aaggttttga
      541 attggcagtt ttgaaaaatg cgcgaacctg ttggtagaaa aaagaagtgg tttttaggcg
      601 ggaaattttg tcaccctctt ttataatctc tttttaaacc tttttttaaa cctctttacc
      661 gtcggctgtg tccttactcc ttcaatggat acagcgtttt ataaactaca ttttgtctgc
      721 ttttaaacta cattttgtct gcttttaaac tacattttgt ctgcttttaa actacatttt
      781 gtctgctttt aaactctttt tttgcactca cgtatgttat aatatgcatt atcacagaca
      841 aaacgttgtt tataacgtct gtatccattg aaggagtaag gaggaatatc tttggcaaat
      901 gaaatcgtga aataccatca tgaattaaat accattccgt tgcggaaatt tacaccagtt
      961 gaaatgaatc tatttttctc tattgtgtct agaatgcgcg aaaaaggcga taaaacagtc
     1021 cgtcttactt ttgaccaact aaaagattta agtaattata aagcaactgc taataatcgt
     1081 ttcattaatg atttagaaat gacttatgat aaattaatgg atttacgttt tggtaaaaga
     1141 agtgctaatg ggctcgatat agatagattc gttatgttta gtgagtttaa aatacgtgga
     1201 actgctaaag atccatatgt agacatacaa gtttacgaaa aagctttacc tttactaaac
     1261 aatttagatg agtgggttcg ctattcactc caacaattta acgaattaca aagtagctat
     1321 gcaaagacta tgtttcgatt actaaaacaa tatcgaacta aaggttttgc ttatttttct
     1381 aaagaggatt ttcatgaact attagatatt ccaaaaagtt actggaacaa ccaagcaaac
     1441 gttgataatc gtgttataaa gcctatacga caggaattaa ccgcaatctt caaaggatta
     1501 tcaatcaaaa agaaatacgg aaaagggcga ggaaaacctg tcgttggcta tcaatttacg
     1561 tttaaaccag aaatcaaaaa agcagatgat tttaataaac atgcaccaac caaagaagaa
     1621 caaaataaag cattggcttt agctgataaa caaaaagaat acgaagaacc tgctacaaca
     1681 attaacgaaa aaatcaaaca gaagaaacga gaacttgaac tcctccaaca aatcaaacaa
     1741 ctagaaaaag agaaagaagc tcttgaaaaa caaacagagt ccgcactttc gaaaaaagag
     1801 aaaaaaagtt tattatctga tttagataat ttattccagt agcaacctag gaggcaacca
     1861 gtatgcaacc acaagaaacc tttacaataa aggaattgtc agaacttttt aagatgagta
     1921 ggcaagcaat atcgaaacat atccaaaaat tagattcttc catgatagct aaaaatgagc
     1981 gtggttataa ggttgtattg cgttctggag tattgcaact tgctcgcaac ttaggcaacc
     2041 aaatgttgct agataggttg cacgagtacg aacaagacaa cgataaaaat gttaatatac
     2101 caagcaaaaa cgtggttaca aacaagttgc tagatcagtt gcgtgaagaa aatgaatttt
     2161 tacgagaaca acttgccctc agagagcaaa ataattctca tatacaaaaa ctactcgacc
     2221 agcaacaaca actcacccta caagccaaca aacaaatcga aaaactgcaa gaaaaactac
     2281 agttgactta tacagaagaa gctccagaga atgactcaac gactctttct gaagcaacag
     2341 aaacaataga caaacaaatt gatactgaaa aaaaatggtg gcaactttgg aaataactgg
     2401 agggaacatt catgacaaga aaaaatcttc tattcggttc tattttacta ggaattctag
     2461 gattcagtcc gatgttattg tcagtgatca ataaagggaa taaacatggt gaattgaaat
     2521 tgaatccaaa ttattacaac agtcctaacg aagaattgtt tgtaaaagaa acagataaat
     2581 aataaaaaag actgctcttt cgagcagcca gttaaaaaat aatgagtgtt tattcttgaa
     2641 aaagcaacgc gcttatgaag cgctaccaaa aatttatcat attttattaa aaataacaac
     2701 ccagtaaaaa atgactggta aaaattcaca aagaaacgga aagaagcaac cgcagaaaat
     2761 caagcttaaa aagagctttt gacctagacc aatcgaaaat cacaaagtga gcgcctgtat
     2821 ctattgctac aggcgctact tggcatagtg tacattatgt caacaagaat ttaatataac
     2881 atattttcct aatgcattct aactatacca cattatcaaa aatataaatt atctttacta
     2941 aataaaatat tgacaagcct ataccttttg ttttatgatt ttcacaaaga aaacgttttc
     3001 tatatatttt tctgtatcag gaggaaattc tatgaaaaaa tttactttag gggtagcttt
     3061 gttaactatt ggggcagttg ttttaccgtc aactactata gtttatgctt cagaaaattc
     3121 ccaagtggta tcattaaacg aaaacaatgc tactgaaaat gtagttattg agtacactga
     3181 agatggtatg gtcgtaacta aatatgagga tggttatagt gcggaagatt ttgcaaattc
     3241 ttcagatatc atgacaagag ctgcagttgc aagatggggc aaaaaggaat atacaaatat
     3301 tgctgtaacc actggagtag ctgctaatgc tattaatgct gccttttggg caggagggaa
     3361 agctagcact tctatgtttg gtatcccagg ttgggcaatt ggtgctttgt taacaggtgc
     3421 aagttggact aaaaaaggtg cttctccagg gaatgcagtt gcaaaagaat gggacaaaaa
     3481 tggtaatggc tggattggat tttattacca aaggggatat gatgcagctg gaagagttgt
     3541 agctactaga tattcaacgt tataagttaa ggagtgatgt ttttgatatc taaatcatta
     3601 aaatcattaa aaacatttac taaaaagaat ccgcaaatag ctactattcg tatttttata
     3661 tttgctatag ctgttgctat aattgttaat atgctaagcg gagggcaatt atacaaatct
     3721 ggtttatttt tagtgttaat cttagttgtc ttagacataa taaagtctaa aaaaaaataa
     3781 atcgatacat tttagaagaa tagggttgtt tgaatattac aaagcaacaa tttcaccttc
     3841 ggtgaaataa gcgaaacttt acaaaaagtg gctagcaaat gctagccttt ttttgtattg
     3901 tggagcgtgg attttgaggg ggattcaagg gggagcttgc gctcctttga caagcggtta
     3961 tttgcaccaa atacggaggt atttggctag caaatataga gcttgccaaa cccttttagt
     4021 gagctttact cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga
     4081 cgtactgaaa gggtgggact tatgagcgaa caacatcaaa atttggctag c
//
LOCUS       DARBDN010000157         4047 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000157 DARBDN010000000
VERSION     DARBDN010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.162"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(156..1661)
                     /locus_tag="SCH06_002736"
     CDS             complement(156..1661)
                     /locus_tag="SCH06_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEG1079252.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1658..2344)
                     /locus_tag="SCH06_002737"
     CDS             complement(1658..2344)
                     /locus_tag="SCH06_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1079253.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2537..3958)
                     /gene="gndA"
                     /locus_tag="SCH06_002738"
     CDS             complement(2537..3958)
                     /gene="gndA"
                     /locus_tag="SCH06_002738"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEG1079254.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1115 a          856 c          692 g         1384 t
ORIGIN      
        1 gttcatctaa aagatactta catttaatta acggatgtta ttctatttaa ttgttcgcta
       61 gtttttttat aatgacatcc ctgaatttct cacttgcttg tattttgtac cttattcttt
      121 gttggatata taaaaaaaca agtaaagcac atgctttact tgtcttctgc ctttgcgata
      181 ggaataaaga ttctaaaaat tgtcccttgc cctactacac tttctgctaa gatacgtcct
      241 ttatagtttt caaccagttg tttagcgata gacaacccca gaccatttcc acccttcgtt
      301 ctagctcttg ctttatccac tcgataaaaa cgattgaaga tcttattaag gtcttctttg
      361 ggtattcctt cgccaaagtc ctgaatcgcg atctcaaatt cattcagagt ggaagaaata
      421 gagatatgga cttcttttcg tgtagttgaa tactttactg cgttatccaa tatgataatg
      481 attaattgtt caaagtgatt acgataaatt tgcagggtca cttcttttgt caaatcatca
      541 tctaaagtga tcacatagtc tggatataat atcttgaaat tattataaac ttgataggtg
      601 acttcttttc ctttagttgt ttcattcgca taatgaacat ctacttgttc tgctcttgat
      661 aagtctagca tctcttgaac taagcttttc atacggctga tttcttgcat gctggcgctt
      721 aatgattctt ctaatatctc aggatcatct ttcccccaac gatttagcag actaagatgc
      781 ccttcaataa ttgcaacagg tgtccttaac tcatgagata cgtcttccac gaattgctct
      841 tgttgttcaa tatacaaacg catacggtca agcatctcat tgaatatttc agctaaatct
      901 gccaattcat catttgtgtc gatttcaggc atgtggatat ctgattgcgg atctttacgt
      961 atagtatcca ttgtatctct gagtaccttg agtggtttta agaaataaga agataaaaag
     1021 aaacctaaaa tactacttaa gatcaaagaa acaacttcta aaacaataag agtcaataat
     1081 agcttatttc gaatatcata gaaagaagat aattcataga agctttgcgc atagccgatc
     1141 ttttctcttg tacctttaga atatataggc tggatagata aaaagccagt ttttccttct
     1201 agtgtaacga tcgttggaac tttacgtgta gtctgaatca ggtttcgact gttttcatgg
     1261 gttttaaaaa tcaagttctc gtccaaatca taaacataaa gatccattga tggctgccct
     1321 agctcagcta taaaggaatc gatcttcatt aagtttcctt cgaccagtga agtatgatct
     1381 acgacctcat ctccgtcatt tgtcgctttc gtcagattac gatacgtatt tactaatgtc
     1441 agttcttcat ccgagttagc caaacgagaa gctacttctg aaatcgtacg ctctacattg
     1501 tttctttctt ttgccacaat cagattgata gatgatttat aggtaatgac agcgaaaatt
     1561 gtaaacacaa cgaatatgaa gaaagaactc gcaaaggccc acttgattgt caaggagggc
     1621 cctttcagtt ctcttttttc cgattttttc ggctttatca cgagcgcatc acataacctg
     1681 ttccgcgtac agtttggata tagctttcct ccccgggaac gtcaattttg ttgcgaagat
     1741 aacgaatata tacgtccact acgtttgttt caacttctgt ttcgtatccc cacactttat
     1801 ttagtaaaac gtcacgtgct aataccacgt tcacgttttc cattaaagta agcagcaact
     1861 cgtattctct ttttgttagt tcaattactt catttccgcg acgtacgaca cggttttctt
     1921 tttcgatagt caaatcgcga taagtaatag tagtttgttt agccacattt ttatcgcctt
     1981 caatatcgat tcgacgcaac aatgcacgaa gacgtgctaa taattcttcg atagcaaatg
     2041 gtttgacgat gtagtcatct gctccgtggt caagtccaga tacacgatcg atcacagaat
     2101 ctcttgcagt catcataatg attggtgtat ttttgacttg gcgtacacgt ctgcagactt
     2161 ctaaaccgtt caattctggg agcatcagat ccaacaatat ggcatcccac tcattattta
     2221 atgccgcatc taaaccagtt cggccgttgt agtggacttc tgcgttatac ccttcatgct
     2281 tcaactctag ctcgacaaat cgtgccaagt tcttttcatc ttcaatgatt agaatattgc
     2341 tcatttatta ttttatcctt tctattctac tggcttttta aaaactctat cattataccg
     2401 ataatatgct taaaaatcta tagtcatttt atcatggata gcaattttaa aaaagagctg
     2461 aagtctactc ataacaatcg acttcagctc tttcgtcctc tttttatttt ctcatttcct
     2521 aacagccgaa agactattat tcttcatggt accatgagta atggaagatt ccttctttgt
     2581 cgacacgctc ataggtatgt gcgccaaagt aatcgcgttg ggcttggatt atatttgcag
     2641 gcagacgttc tgctctgtat gaatcgaagt aagcgatggc tgatgagaaa gtcggtacag
     2701 gtacgccagc ttggacagcc aaggcaacga cgtctctgac tgattgctga tattttttcg
     2761 tgatttcaac gaagtaatca tctagcaata aattttcgat ctcaggattt ttgtcatagg
     2821 catccgtaat tttttgcaag aatcgagctc ggatgataca tccagcgcgc cagatttttg
     2881 cgatttcacc aaatggcaag tcccaatcaa attcttttga agcgacacgt aattgagcaa
     2941 atccttgggc ataactcatg attttactga aatacaacgc ttctcggatt ttttcgacca
     3001 attctttttt gtctcccgtg aactcaaaat cgttcgtacg agacaaaatc ttgcttgctt
     3061 gtacgcgttc ttctttataa gcagaaatat agcgggcaaa tacagattca gtgatcaatg
     3121 gaagtggcac acctaagtca agcgcgcttt ggcttgtcca tttacctgtt cctttattcc
     3181 cagctgcatc aaggatcaca tctactactg gtttacctgt tccttcatcg tctttacgtg
     3241 tcagaatgtc agcagtgatt tctatcaaat agctgtctaa ttcgccttga ttccattctt
     3301 taaagatatc agccatttct tctactgaaa ggtttaaaat attcttcatt aagtcataag
     3361 attcagcaat cagttgcata tctccatact caataccgtt gtgtaccatt ttcacataat
     3421 gtccggctcc atttgggcca atatatgtga cacatggtgc tccgtcttct gcttttgcag
     3481 aaatttgctc taagattggt gcaactagcg cataggcttc tttttgtcca ccaggcatga
     3541 ttgaaggtcc ttttaaagct ccttcttcac caccggaaac gcctgtaccg ataaagttga
     3601 tgccagagtt ggctaactct tcattacgac gcatcgtatc tttaaagaat gtatttcctc
     3661 cgtcaatcaa aatatcgcct ttatcaaggt gaggaagtaa ctcttggatt gttgcatctg
     3721 ttgccggtcc tgctttgacc attagcaaga tccgacgtgg tttctcgata gattctacaa
     3781 attcttcgat tgtatatgtt gctttgaaat ttttatctgg gtgttcttct actacagcgg
     3841 ttgttttagc ccctgtacga ttgaataaag ccactgaata gccgcggctt tctatgttca
     3901 aggctagatt tttacccata acggccatac cgacaacgcc gatttgttgt tttgacatat
     3961 gaactcctcc tacatacggg atttctccct aatctcttac attatagctt aacacggcta
     4021 cattgcaaac taaagaacaa catattt
//
LOCUS       DARBDN010000158         4001 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000158 DARBDN010000000
VERSION     DARBDN010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.163"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(480..767)
                     /locus_tag="SCH06_002739"
     CDS             complement(480..767)
                     /locus_tag="SCH06_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEG1079255.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(787..1011)
                     /locus_tag="SCH06_002740"
     CDS             complement(787..1011)
                     /locus_tag="SCH06_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HEG1079256.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(1466..1636)
                     /locus_tag="SCH06_002741"
     CDS             complement(1466..1636)
                     /locus_tag="SCH06_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079257.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(1651..2184)
                     /locus_tag="SCH06_002742"
     CDS             complement(1651..2184)
                     /locus_tag="SCH06_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEG1079258.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(2205..3149)
                     /locus_tag="SCH06_002743"
     CDS             complement(2205..3149)
                     /locus_tag="SCH06_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HEG1079259.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            3786..3872
                     /locus_tag="SCH06_002744"
     CDS             3786..3872
                     /locus_tag="SCH06_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEG1079260.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
BASE COUNT         1138 a          740 c          622 g         1501 t
ORIGIN      
        1 gctagccaaa tattgatttt gttcgctcat aagtcccacc ctttcagtac gtcctacgga
       61 cgtatcgttc gcaataccat tgtacctaaa aaggtacaat aagtaaagct cactaaagct
      121 cactaaaggg cttggcaagc tctatatttg ctagccaaat acctacgtat ttggtgcaaa
      181 taaccgcttg tcaaaggggc gcaagctccc ccttgaatcc ccctcccccc cactctccac
      241 aatacaaaaa agactagcaa atgctagcca ctttttgtaa agtttcgctt gtttcacctt
      301 cggtgaaatt gttgcaaatc aataattagg tagagctaca tttttttcgt tgttcaaaga
      361 ttcttatgcc atttactatt aataaatcta taaatatgat aatttttcgg ctctataatt
      421 tatgggactg atgaatcaga attgattctt cagtcccatt ttcattttat tccaaagaat
      481 taactccaaa taccaataga agcccatcct ctatatactt gagattcctt actaacaatt
      541 tcttgtaatt ctattaaaga tttaggtaat ccaaatttat gttttaaaat atatcttcca
      601 agaaaactac ttaatttcat actaacttca ccaacacttt ttccctcact gatttcttta
      661 gaataaagaa agagcttttc ttttaagtca ggatagtcat ctatagttgc ttcattgtat
      721 actttactaa ttgcatttaa aagtttttct tctttagtaa aatccattat aataacctcc
      781 ctaccactac cttctaggtg cccatggacc atgattaacc caaccattaa caataatttt
      841 tccaatttct cctttagctt gattccaatc tacccaacat ttttctttgt tacaataaag
      901 accatttcca tagtaagtag ctgcatcaac ttttattcct gtaccgatgc cagctagaca
      961 agttcctaat attcctagaa taacacaatg ttttaatact ttctttttca tgattgtttt
     1021 tccttttcgt ttttttaaaa ttgcttgtta tattaaataa tcttagtaat tttattatat
     1081 aacattttat tatataacaa tgattaacgt cataaaaagt agttttgaat tcataatcgt
     1141 ttaaataaaa ttataagatc agttatttaa acagctagta gacataatgt gtatactacc
     1201 aagtaacgcc tgtaccaagg gatccaggcg ctgattttgt gaatttttat tggtctaggt
     1261 taaaagctct ttttaaggct tggttttctg cggttgtttc tttctaattc tttgtgaata
     1321 ttgatcggtc attttttaaa tacttgttat ttttgtttgt gtttgttatg ctttttacat
     1381 atctcatatt catttattat tcttttctaa ggttaataat aggataatct ctttcagaaa
     1441 gactgctcgt acgagcagtc ttttcttatt tatcaagttt ttctacaaat acttcctcat
     1501 tttgactgtt gtagtaatta ggattgagtt ttagttcccc ttttttattt cctttgttgg
     1561 ccactgataa taacattggg ctaaagctta atattcctag taggatagaa ccgaatagca
     1621 agtgtttttt tgtcataagt atttccttct tcatttccat agctgccacc attttttcca
     1681 attctttgtt tgttcgtcca ttgtttctgt tgcttcagaa agagtcgttg aactattctc
     1741 tgaagactct tccgtataag tcaactgcag ttgctcctga agtttttcga tttgttggtt
     1801 ggcttgcagg gtgagttgtt gttgctggtc gagtagtttt tgtatatgag aattattttg
     1861 ctctttgagg gcaagttgtt ctcgtaaaaa ttcattttct tcacgcaact gatctagcaa
     1921 cttgtttgca accacgtttt tgtttggtat ataagcattt ttatcgttgt tttgttcatg
     1981 tttatgcaac ttatctagca acctttgatt gtctaagttg cgagcaagtt gcaatactcc
     2041 agaacgcaat acaaccttat aaccacgctc atttttagct atcatggaag aatctaattt
     2101 ttggatatgt ttcgatattg cttgcctact catcttaaaa agatctgaca attcctttat
     2161 tgtaaaggtt tcttgtggtt gcatactggt tgcctcctag gttgctactg gaataaatta
     2221 tctaaatcag ataataaact ttttttctct ttttccgaaa gtgcggactc tgtttgtttt
     2281 tcaagagctt ttttctcttt ttctagttgt ttgatttgtt ggaggagttc aagttctcgt
     2341 ttcttctgtt tgattttttc gttaattgtt gtagcgggtt cttcgtattc tttttgttta
     2401 tcagctaaag ccaatgcttt attttggtct tctttggttg gtgcatgttt gttaaagtcg
     2461 tctgcttttt tgatctcagg tttgaacgta aattgatagc caataacagg ttttccccgt
     2521 ccttttccgt atttcttttt gattgttagt cctttgaaga ttgcagttag ttcttgacgt
     2581 ataggtttta taactcgttt atctatatca ggttgcttat aacttttagg aatatctaat
     2641 aattcaagaa agtcttcttt ggagaaatat gcgaaacctt tggttctgta ttgctttaac
     2701 agacgaaaca tagtctttgc atagccactt tgtagctcgt tgaattgttg taaagaatag
     2761 cgtacccact cgtctaaatt atttaacaaa ggcagtgctt tttcgtaaat tcgtatatct
     2821 acgtaaggat tttctacgtc cccgttgatt ttaaattctg taaacattac aaacatatcg
     2881 taagaaagcc cagactcact tctacgacca aagcgtaaag ataagatttt ttcataagtt
     2941 gcttttaaat cttctacaaa tcgtacattt gcagttgctt tgtagttact taaatctttt
     3001 agttggtcaa acgtaaaacg aactgtctta tccccttttt cacgcattct agacacgatg
     3061 gaaaaaaaca aattcatttc aaccggtgta aattttctta aaggaattgt atttaattca
     3121 tggtggtatt ttacaatctc attagccata taatcacctc aatccaatta tgaatgacat
     3181 tttttaaatg tcaagacatt catatttgac gttcaaacag acaaaatgtc cttcataaac
     3241 agacaaaatg tccttcataa acagacaaaa tgtccttcat aaacagacaa aatgtccttc
     3301 ataacattct gtatccattg gtagagtaag gacacagctt acggtaaaga ggtttaaaaa
     3361 gaggtttaaa aagagatata aaaagagggg ggctaatttt cccgcctaaa aaccacttct
     3421 tttttcttta aacaggttcg cgcatttttc aaaactgcca atccaaaacc ttgcttccta
     3481 cggtcgccaa aaaggtgtga tcgctacgct ctcacattgt actgcgcagt cgcctaaagg
     3541 ctcctttgct aaaaacatgt tggtaaagag gcctttgagc ggttctgaat gcttatctaa
     3601 gccgttttaa gacagtcttg gataaaaatc cttatctagc tttaaagcgc cttacaggcg
     3661 gtcagggcaa gccctaacaa ccctaaaata agcgatactt aaaaacacca cacaagttta
     3721 attttttaag atataataac ttgtcgccta tccgacagtc ttgcgactgg aaggaggtgt
     3781 atctaatgtt tgaattgttc atttgccccc ttcttataga agtttgtgtc tctttattca
     3841 gttattggtt gaataaccga aacaagaagt aaaatcaata aaggcgacat caacctgaaa
     3901 aaaagcccca gagaatccga cctctctggg gctttcgtgt atctaatgtt tgatcatttg
     3961 catgtttagt ttaacatgat tgccgatcaa attcaatttt g
//
LOCUS       DARBDN010000159         3980 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000159 DARBDN010000000
VERSION     DARBDN010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.164"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            56..715
                     /locus_tag="SCH06_002745"
     CDS             56..715
                     /locus_tag="SCH06_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEG1079261.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            800..1705
                     /locus_tag="SCH06_002746"
     CDS             800..1705
                     /locus_tag="SCH06_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEG1079262.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1707..2339)
                     /locus_tag="SCH06_002747"
     CDS             complement(1707..2339)
                     /locus_tag="SCH06_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEG1079263.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    2490..2615
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2659..3183
                     /gene="infC"
                     /locus_tag="SCH06_002748"
     CDS             2659..3183
                     /gene="infC"
                     /locus_tag="SCH06_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEG1079264.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            3255..3455
                     /gene="rpmI"
                     /locus_tag="SCH06_002749"
     CDS             3255..3455
                     /gene="rpmI"
                     /locus_tag="SCH06_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEG1079265.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            3508..3867
                     /gene="rplT"
                     /locus_tag="SCH06_002750"
     CDS             3508..3867
                     /gene="rplT"
                     /locus_tag="SCH06_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEG1079266.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
BASE COUNT         1338 a          700 c          827 g         1115 t
ORIGIN      
        1 tttaaaaagg ttggagttaa acacaatatt tagtgatgaa gtgagctgga ggtaaatgag
       61 cgtgatcgtt ttagcaggta caattggtgc cggaaaatca agtttaacag aaatgatggc
      121 tgaacacttt gatagtcagg cattttatga atcgattgat gataatgaag tcttgccctt
      181 attttatgca aaccctgaac agtatgcttt tttgctgcaa atttattttt tgaataaacg
      241 ttttgcaagc atcaaacaag caatgaaaga tgacaataat gtattggacc gttcgattta
      301 tgaagattca ctgcttttcc atctaaatgc agatctagga agagcaacag aaacagaagt
      361 tcgtgtgtat gatgaactgc tggaaaacat gatggaagaa cttccctatg ctgcccataa
      421 aaaacatccg gatttattag ttcatattcg tgtatctttt gatacgatgt tggagcgtat
      481 cgaaaaacgt ggtcgttcgt atgaacaatt gtcctttgat ccaagtctat acgattatta
      541 caaagaattg aacagacgtt acgatcaatg gtatgaagaa tacaaagaaa gtccaaaaat
      601 ccaaatcgat ggagaccgct ataattttgt ggaagatcct caagcaaaag aagaagtctt
      661 gaaaatgatc gaagaaaaat tagcagagat tcgccaaacc aaagtagcca tttgatttac
      721 agttgctcaa ataaagggta aacctttatt tgagcgactt ttttctttat actggaaaca
      781 aatgtcagga ggatagagta tgcgggaaaa acactatttt aatcaagacc gtaatttttg
      841 gatcaatgta cagcaaaacg atgtgctagc tgttaaaaac ttaaaagaag aatatggcat
      901 tagtgacgag atgctgactt attctctaga taaaaatgaa cgggcgcgcg tagagtacga
      961 ttcttttgat gaagcgttac tgcttgtatc aaatgttccg caccagcaaa aagtcgataa
     1021 tcattatgaa actagtccta tcgcttttat tttaaaagaa gacggtttgt ttacatttac
     1081 cacgccgaat accgagtacg tgattcgact aattcgatcg cttttggaac gaatgccaga
     1141 catgagtgta tacagtttat tgtttcgtac attgtttttg atttctgatt ccttttttcc
     1201 tttaatcgag gaagtgaata gtgaacgtca gcggcttaat ctgaaattaa gagaaaaaac
     1261 aacgaacaag aatctgctgc aactttcaga tttagagatc ggtttggttt acttagttac
     1321 aggaacaaaa caaaatgtag tacttttaga acaaatcaag gcattggcta tttatcgcaa
     1381 gttgtcagaa aaggaaaaag aagagttgga cgatgcgctg atcgaagcac gacaagcagt
     1441 tgaaatgacg aacttagctt cgcagatttt agaccagctc tctggcactt ataataattt
     1501 gctgaataac aacttgaatg acacgatgaa atttttgacg gtctggtcgc tgatcttgac
     1561 cgttccaact attgtgacag gattcttcgg aatgaatctc cagttaccct ttacccattc
     1621 cgttttcgga tggggaatcg ccttgatcat cagtttggtc ttatctattt ggatgcttat
     1681 tgcactgtgg cggcggattc gttgatctag tctttgatct gcaaaccaag ggcttgggcg
     1741 atcacaagtg cttgctcttg gttgacgatt agtcccgcca aagaatcttg agataaagcg
     1801 attgctgtga agaaattagt cgtaaagtct aatcccttca gagaagttcg aaaccagttc
     1861 gaaccggtca actgattgtc agacaaaaaa aggtttttcc aagtgacctc ataaaattcg
     1921 ctgtcttcta attgacaatg atcgaaggag acagctttca agtttgtact actaaaggaa
     1981 gccatcgaag caatacaatc agtgaaagta cagtctcgaa gataactttc ggcaaaattc
     2041 gtacctgtta atttacattg atgaaacacg acttggtgga aactgccacc aatccactcc
     2101 agattggaaa aatcacattt ttcaaaaatg acattactgc attcaaaatg acgtaaaact
     2161 gttttttgca tcgtaagttt ttggatatga ctctctctta ataccatatt tttggcatcg
     2221 agatagcttt ggtcaccccc gttgatcaga agaccagaga agatctcctc atcttctaaa
     2281 taaaactctc cctttgtaag aagaggaaga gaaggtggaa taggttcgat ttttttcatg
     2341 tgggttcacc tcgtttttct ttagtatagc aaagaagcgg gaatcactgc tagaaagtct
     2401 gctaatctaa tcattttcag aaaaggaaga caaactgtat gaaaaacatt gacaaaaaga
     2461 ttagtttttg ctatactatg atggttgaga aataaaagca gaagcacccg cttctcgcct
     2521 tagttgataa tgtcactggg ctagatagtt ttcactggtt ctattaggtg aagtacgcgc
     2581 gggttctgta agagaactcg tttttttatt gccgtttatt cggtaagctt ttctttctct
     2641 cataatattt ggaggtgaat gaccatagca aaggatatga tggttaacga cggcattcgt
     2701 gcacgagagt tacgattgat cggttcagat ggtgagcaat taggagttaa gacaaaagca
     2761 gaagcattga atattgcaga acaagcaaac ttggatcttg tgttagttgc ccctggtgcg
     2821 aaaccaccag ttgcgcgaat catggactac ggtaaatacc gtttcgaaca acaaaagaaa
     2881 gaccgcgaag cgcgtaaaaa acaaaaagtg atcaatgtaa aagaagttcg cttaagtcct
     2941 acgatcgact tgaatgactt caatacaaaa cttcgtaatg cacgtaagtt cttggaaaag
     3001 ggcgataaag tgaaagcttc tatccgtttc aaaggccgtg ccattaccca taaagaaatt
     3061 ggtcaaaaag tcttgaatcg cttagctgaa gaaactgcgg atattgcaac agtggaacaa
     3121 aaagcgaaaa tggacggacg cagcatgttc ttgacgctgg caccgaaaaa cgacagtaag
     3181 taatttgaat gactaactgg ctgttggaca gccgatagtc ggataacgaa agattttgag
     3241 gaggaaatat agtcatgcca aaacaaaaaa cacaccgcgg atcagcaaaa cgtttcaaac
     3301 gtactggtaa aggcggattg aaacgcttcc gcgcgtttac aagtcaccgt ttccacggca
     3361 aaacaaaaaa acaacgccgt caattgcgta aagcaagcat ggtttctagt ggcgacttca
     3421 aacgtattcg ccaacaacta gcaaaaatga aataagaagt acaaataaca gaatctgaag
     3481 atttattttt attaggagga attatacatg gcacgtgtta aaggtggaac agtaactcgt
     3541 aaacgtcgta aaagagtgct aaaattagca aaaggttact acggttcaaa acacacttta
     3601 tttaaaacag caaaagaaca agtaatgaat tcatacaact acgcatatcg cgatcgtcgt
     3661 caaaagaaac gcgacttccg taaattgtgg attgctcgta tcaacgcagc agctcgtatg
     3721 aatggcttga gctactcaaa attaatgcac ggtttgaaag ttgctgaaat cgacatcaac
     3781 cgtaaaatgt tagctgactt ggctgttaac gatgcagcag catttactgc attggctgac
     3841 caagcaaaag aagctttggc taaataagct aaacaattat aaagaggaaa gaagataacg
     3901 aaaagttatg ttctttcctc tttttttatt tacaatcctc catcaaatga aacaggacaa
     3961 taacgtataa gtctaaaata
//
LOCUS       DARBDN010000160         3925 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000160 DARBDN010000000
VERSION     DARBDN010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.165"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(573..1130)
                     /locus_tag="SCH06_002751"
     CDS             complement(573..1130)
                     /locus_tag="SCH06_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079267.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="SCH06_002752"
     CDS             complement(1309..1920)
                     /locus_tag="SCH06_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079268.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="SCH06_002753"
     CDS             complement(2033..2290)
                     /locus_tag="SCH06_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079269.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="SCH06_002754"
     CDS             complement(2887..3165)
                     /locus_tag="SCH06_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079270.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="SCH06_002755"
     CDS             complement(3199..3450)
                     /locus_tag="SCH06_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079271.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1195 a          799 c          520 g         1411 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacctctttt
     3781 cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa cttatatttc
     3841 cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag cattacgcct
     3901 gccagaataa accaattatt tgtat
//
LOCUS       DARBDN010000161         3910 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000161 DARBDN010000000
VERSION     DARBDN010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.166"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..503
                     /locus_tag="SCH06_002756"
     CDS             <1..503
                     /locus_tag="SCH06_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HEG1079272.1"
                     /translation="GIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGVLVILEGGMII
                     DTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVMAPLGDLMNVS
                     RDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFAILTLVSAVLL
                     YIATLF"
     gene            536..1381
                     /locus_tag="SCH06_002757"
     CDS             536..1381
                     /locus_tag="SCH06_002757"
                     /inference="COORDINATES: protein motif:HMM:NF013429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HEG1079273.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTYSNCQAVKQLAQKHALDIIAFTPESIIYPYNIAAPETMQWEKSKAYFRNAILA
                     TAELGCSLMTINSGYGLMEEPIEESWKRSREMLRYLAEIAETEGVTIALETLRPEESK
                     IVTKLQEAQRMVHDVAHPSLKLMVDTAAMGVAGEGLQDWFKAFGDDIVHLHFVDGTPE
                     GHLAWGDGNFNLHEFLTILEKYDYQGFLGQEITDSRYLKRPYLADKQVFDKLSEALRK
                     REGNV"
     gene            1378..2166
                     /locus_tag="SCH06_002758"
     CDS             1378..2166
                     /locus_tag="SCH06_002758"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079274.1"
                     /translation="MKDFVAVGYACMDIYDDLGKKYPTGNGVDVIAHLSKAGYDVALV
                     SAVGDDTYGKEFIEFCEDMEFDTSHVHVEEGDTAQIHLSLIDGDRVHGKVIDGVLANF
                     SLTKEDRAFIKEFKYLHTDYFGRIYGMLGEFQQAGCKIVFDFSSFINDKDFEMVAPYV
                     DIGQISVEGFSQETKKIMQYMHCLGIKICIATAGSQGALAYDGKNFYCQEALDPQEIV
                     NTVGCGDAFLAGFLMGDAASKPIEECLLLGAKSSQKIIQKFEPY"
     gene            2187..3050
                     /locus_tag="SCH06_002759"
     CDS             2187..3050
                     /locus_tag="SCH06_002759"
                     /inference="COORDINATES: protein motif:HMM:NF016777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEG1079275.1"
                     /translation="MTIDTCFHPIYFDMIQTSEAELKKREEAFGVHKQSPYTMDEILS
                     EMDYGKIEKSILHPIALTTTENVSIVTNEEISKIIQQEPNRFIGFASVDPNNPEAETE
                     LEQAFQKGLAGLTFHPGKQQIYPNDPKMKPLYQLCEKYDKPIYFHSGLSWEPRSYTKF
                     CQPLFVEDVLIEHPALRICLAHFSWPWIQEVMMLMIKYSNLYTDTSMLYLNSFDDFFG
                     DFFSNQLTPSTIERNFPRQIMFGSNTPRFRAFKVKRALEKIPFSKEVRENILTNNAYD
                     YVYGRKSRHDL"
     gene            3040..3468
                     /locus_tag="SCH06_002760"
     CDS             3040..3468
                     /locus_tag="SCH06_002760"
                     /inference="COORDINATES: protein motif:HMM:TIGR00149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HEG1079276.1"
                     /translation="MIYKEYLEFFSTEDVQLINITEEVEKVMARSNITSGVAFILSNH
                     TTTGITINEPLECVEKDIKNTLERLIPENSNYIHAHFLPSYGATSNNSPGHLKSSLLG
                     NHAMFSVEDGKLEKGSAQDIYLVECDGPQTRKILIKILGE"
     gene            complement(3767..>3910)
                     /locus_tag="SCH06_002761"
     CDS             complement(3767..>3910)
                     /locus_tag="SCH06_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079277.1"
                     /translation="DFREVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYS
                     SLI"
BASE COUNT         1218 a          666 c          817 g         1209 t
ORIGIN      
        1 ggggcatcgc tagattttct caaaaggaaa ttgctgaagc ttttgtcgaa ggctgttcag
       61 atttcgccta tgctgctgta atcattgggc tagctagagg agtcttggta atcttggaag
      121 gtggaatgat tattgacact attctaaaca gcttggctaa ccttttaggt ggtcttccaa
      181 aattcctgtt cactacgatt ctactcattt ctcaagtaat tgtttccttt tttgttccat
      241 cctcctcagg agctgcggca ttaacgatgc cggttatggc accattgggt gatctaatga
      301 atgtaagtcg tgatgttgtt gttctaagta accagtttgg aaatggttta atgaatatta
      361 tctccccaac tagtggtgta ttactggcag gattagccat cgcagagatt aatttctcta
      421 aatggtttaa ggttggcttc aaaatatttg ccatcttaac ccttgtttct gctgttttgt
      481 tatacattgc tacactcttt tagtcttaat catccattaa taggaggcaa tagttatgat
      541 taaaataaat caattagcag gaatgaatat ccactattta ttttattctc tcaaagaatt
      601 tttcgcttat caacagaaaa ttggtatttc ttctgttgaa ctttggggag gtgctccgca
      661 ttttttcata gatgctttta cttattctaa ttgccaagcc gttaagcaac tagcacagaa
      721 acatgctctt gatatcattg cttttactcc agaatcaatt atctaccctt ataacattgc
      781 tgcgccagag acgatgcagt gggaaaaaag caaggcctat tttcgaaatg caatattagc
      841 tacggctgag ttaggctgct cactgatgac aatcaactcc ggatatggtt tgatggaaga
      901 gcctatcgaa gaaagctgga agcgctcaag agagatgcta cgatacctcg ctgaaatagc
      961 agaaactgag ggagtcacga ttgcattgga aacgttgcgt cccgaagagt cgaaaattgt
     1021 aaccaaatta caggaggctc agcgaatggt tcatgatgtg gcacacccat ctttgaagct
     1081 gatggttgat accgcagcaa tgggggtcgc tggagaaggt cttcaagatt ggtttaaagc
     1141 cttcggggat gatattgtcc accttcattt tgttgatgga acaccagaag gacatcttgc
     1201 ctggggagac ggaaatttta atttacatga gtttcttact attttagaaa aatatgatta
     1261 tcagggattt ctgggacaag aaatcacaga tagccgctat ctaaaacggc cttatcttgc
     1321 agacaaacaa gtatttgata aattatcaga agcattgagg aaaagagagg gaaatgtatg
     1381 aaggattttg ttgctgtagg ctatgcatgt atggatatct atgacgattt agggaagaaa
     1441 taccccactg gaaatggagt ggatgttata gctcatctct caaaagctgg ttacgatgta
     1501 gctcttgttt cagcggtagg agacgacact tatggtaaag aattcattga attttgcgag
     1561 gatatggaat ttgatacttc tcatgttcat gtagaggagg gagatacagc acaaatacac
     1621 ttgtctctga tagatgggga tcgagttcat ggaaaagtaa ttgatggtgt actagcaaat
     1681 ttttccttaa caaaagagga ccgggcattc atcaaagagt tcaagtatct acacacagat
     1741 tattttggcc gcatctatgg gatgctagga gagtttcaac aagccggctg taaaattgta
     1801 tttgattttt cttcttttat caatgataag gattttgaaa tggttgctcc ctatgttgat
     1861 attggacaga tttctgtaga aggattctct caggaaacta aaaaaattat gcagtatatg
     1921 cattgtttag gaatcaaaat ctgcattgcc actgctggaa gtcaaggggc tctcgcctac
     1981 gatggaaaga atttttattg tcaagaagcg cttgatcctc aagaaattgt caatacagtg
     2041 gggtgtgggg atgctttcct cgcgggtttc ctaatgggag atgcagctag caaacctatt
     2101 gaagaatgtt tgttattggg agctaaaagt tcacaaaaga tcattcagaa atttgaacct
     2161 tattaattga cagaggagcg gaagtaatga ccatagatac ttgttttcat cctatctatt
     2221 tcgatatgat tcaaacatca gaagcagaat taaaaaaaag agaagaggct ttcggtgtac
     2281 acaaacaaag cccctataca atggacgaaa ttctttcgga gatggattat ggaaagatag
     2341 aaaaatcaat tcttcatcca attgctctaa cgactaccga aaatgtcagc attgtgacaa
     2401 atgaggagat tagcaaaatt atccaacagg agccaaatcg ttttattggt tttgccagtg
     2461 tagatcccaa taatcccgag gcagagaccg aactggaaca agcctttcaa aagggacttg
     2521 ccggtttaac tttccatcct gggaaacagc aaatttatcc gaatgatcct aaaatgaaac
     2581 cgctttacca gttatgtgaa aaatatgaca agccaattta ttttcactct ggtcttagct
     2641 gggagccaag aagctacaca aagttctgtc agccactatt tgtggaagat gtattgattg
     2701 aacatcctgc gcttcgaatc tgtttagcac atttttcatg gccctggatt caagaagtga
     2761 tgatgttgat gataaaatat tcaaatttgt atactgatac ctctatgctt tatttgaact
     2821 cttttgatga cttctttgga gattttttta gcaatcaatt gactccctca acaattgagc
     2881 gaaattttcc aaggcaaatt atgtttggat caaatacacc acgttttcga gccttcaaag
     2941 tgaaacgggc tctggaaaag attcccttct caaaagaagt gagagaaaac atcttgacaa
     3001 ataacgctta tgattatgta tatgggagga aaagtaggca tgatctataa agaatactta
     3061 gaattctttt ccacagagga tgtccagtta ataaatatta ctgaagaggt agaaaaggtt
     3121 atggcgcgga gcaatataac aagtggcgtt gcctttatcc ttagtaacca tacaacaacg
     3181 ggcatcacaa tcaatgagcc actggaatgc gtggagaagg acataaagaa tacactagaa
     3241 cgattaatcc ctgagaattc gaactatatt catgcacatt ttcttccctc atatggagcg
     3301 acaagtaata actctccagg acatttaaaa tcctccttac taggaaatca tgcaatgttt
     3361 tcagtggagg atggtaagct ggagaagggg agtgcccaag atatttattt agtagaatgt
     3421 gatggacctc aaactcgcaa aattctaata aaaatactag gagagtagtt ttgaattacc
     3481 ggaagggact gggacaaaag ttttttctta aaaaatagtc ccatttcttc agtattaatt
     3541 aaataaaaag taaaatacat tcccgaaact attggatgaa gatcccagta gtttcgggaa
     3601 tgtatttttt ctagaggctt tcttttgctc tttgtcaaga agtgttgatg acgagatttt
     3661 ctaattcaaa tgaaggataa tttcacaatc tattaagcag tggctaggaa ccaattggtt
     3721 cctaagttgc tgcttttatt tctaataatt tatattctat gatttgtcaa attaagctag
     3781 aataaaatgc ttcttgtaca tagctcaaaa atatttcgat tggtgttctg taattcaatg
     3841 attttcttgg aatatgatta cgttgattgc tgacactgga aataaatgtc tgattcactt
     3901 ctctaaaatc
//
LOCUS       DARBDN010000162         3876 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000162 DARBDN010000000
VERSION     DARBDN010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.167"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            158..2257
                     /locus_tag="SCH06_002762"
     CDS             158..2257
                     /locus_tag="SCH06_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEG1079278.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2453..3316
                     /locus_tag="SCH06_002763"
     CDS             2453..3316
                     /locus_tag="SCH06_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEG1079279.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3421..>3876
                     /locus_tag="SCH06_002764"
     CDS             3421..>3876
                     /locus_tag="SCH06_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEG1079280.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
BASE COUNT         1544 a          646 c          782 g          904 t
ORIGIN      
        1 agcttgagac tacgcagtct caagcttttt tttctatagg aaggaaattc attcattatt
       61 tttaagtaaa tcctaaaaat aagctattgg cgtgacgtat agaatatgat agattaaatg
      121 gtagcgtaaa cctagtaaag gagccgatcg ctaagtgatg aaaaaatgtc caaattgcgg
      181 atcgaaaaaa atggagcaga atactatctg tccagactgc ggtcatcaaa taactgcaga
      241 agatcagcaa ataaaagaat caattgaaga aacaaataca gatgcagcta tgcaggataa
      301 atcaactgaa gatgcagtct ttcctgatac agaattaaac gatccaatcg aatggtcgga
      361 attgaaagat ttacctctag aatctgtaat ggaattattc gaaaaagcag aaccagaaga
      421 cgaagaacca cctgctcacg atcaagtaac taatatagag aaaaatgaac agaagaaagc
      481 aactgttcat gagacttcgg aagaatcagg aaagaatcaa gaagaaacgc ttgaatcaaa
      541 acaaaaaaga agagtagctg aactgaaaga aatcgtcgat aatgaggaag aaaattcgat
      601 actatccgct tatatcaaag cacatcgtga agatacaaaa gaagagcacg cgaaagagct
      661 gctcaaaatg atcagtgaaa aaattgcaca ggaaaacaaa gtagagccag aaaaggaaca
      721 agaaactgaa aaagactctg atagagaaaa cgccacaggt aaagaaacag taaaaataaa
      781 agacgtaaaa acggatatca cagaaaaaac tgaagtattt actgaaaaac aattagaaaa
      841 ggaaaaaacg aataaactgc cggaagcaga gaaaaaagaa atactcgaaa acacagacaa
      901 aaagtcaaca gagcccgatg aaataaatag tgaatccgat gctgaaaatc aatctgtaag
      961 caaagagggt actgatcttg aagcaaaaat agaaaaagaa gagaaccagc ctaagctgtt
     1021 tgaagcagaa gcgaaatcaa taacaatcgt gccagatact gaaaaaacac atcaagaatc
     1081 aaacttagaa aaaacagatc cagataaagc gcaaaagaaa aaatcaaaaa aagtacctta
     1141 tctcgtttta gcagcagtac ttctactcgg tggaggaagc tgggcttatt atgaccatca
     1201 tcaaaaagta gaagccgaag tagcagcaga agcaaaaaga cagcaacaaa tggaagaact
     1261 tcatgagaaa cttgctgcct tttatacaga tgatcaccat caatttattc gtgcagatat
     1321 gattcatcaa gatttatcaa aactaaaaaa tgatttatcc agtcttaaga atgaaaaagg
     1381 atattcagag ttagaaacaa cttaccaaga tatccaatct aagatccgag atatccaaaa
     1441 agtgaatgag tggttcatag cacctgccat cgtcgatgat catctagcag atgacatcaa
     1501 gttgaaagca gataaagaga tccaagcaat cgaaacggat aacacagatt ttggaaaatt
     1561 gattcaacaa gcacaaacag aagctaaaaa tcaatatgct gaattgcaaa cagctaaaga
     1621 aaaaacagct atagtcttta aagacggaaa agtagtggat tcagcaacac gcgaccaata
     1681 caagacggca aaagaagcag tagaaaaagt gaaaaataca gatctatctg ctcagttgaa
     1741 tgaacaattg aaacaagtag ataagatgct cactgataaa gagaaaaaag aagaagagga
     1801 aaagaaaaaa gcagaagaag cgaaaaaagc agctgaagaa caagcaaaac aagccgctca
     1861 agcagcagct gcagctcaag ccgctcaaca agctgcggtc gcacaagcag cacagcaaga
     1921 agcggcatcc tcgacccctt cctcttcaaa ctcagcgaat cagccaatca aatctgccag
     1981 agcaagtgat attgccgatg catctaatcc agcatggacg tgggcaccag gtgtccaaag
     2041 caaagtgatt gctacatgta tccaacgtgg atatatcgtt gaaggaggtt acagattaga
     2101 aaaagccaga atcgaaaatg gggaaggcta ttataatcta tatgccactt caacaaaatc
     2161 tgcattgatg aaaggcattg gagaaagtgc tttgccattt tacatcgtaa ccatcaactg
     2221 taaaactgga tggttcggag gaaatgggag caattaattt taggcaaatg aaagaggctg
     2281 tgagcctgcc gtttaacacc gtttattcga aaaaggggag tatgacacaa ctgttgtcat
     2341 actccttttt tcacctttcc aaaccaaggc tcagctattc aagtagataa cattatgtta
     2401 tgatagcaaa gaaatgtatt aagaaaacct ttcactatag agggagaaaa aaatgaacga
     2461 tttattagca actatattta caggtattat tattgatgaa aatgaaaaaa actactttgt
     2521 ccaaaaaaac ggacaaacct ttggcttaag caaatcagaa ggtgaacaca aaatcggtga
     2581 agcagttgaa ggattcggtt accaaaatca aaaacatgaa aatcggatca ctacacaaat
     2641 tcctaaaagc cgtatcggtc attacgcttt tggaatcgtt actgctacac gaaaagattt
     2701 aggtgcgttt gtcgatatcg gtcttccaga taaagacttt gtcgtatctc ttgatgaatt
     2761 gccgacaatg acagagctat ggcctaaaaa aggggatcgc ttgatgattt cccttagagt
     2821 tgatgcaaaa gaccgtattt ggggcagttt agcagatgaa aaaatattca aatctttaag
     2881 caaatatgga acagaagaaa tgaaaaacaa agatgtgata ggaacagcat accgcttgaa
     2941 attaacaggt acgtacgttt taacggaaga tttctatctt gggtttatcc atccttctga
     3001 acgatataat gaacctcgtc taggcgagca gataaaaggt cgagtgattg gtgtccgacc
     3061 agacggtgta ctgaatcttt cattgaagcc aagagcatat gaagctatat cagatgatgc
     3121 acaaatgatt ttaaccattt tagaacgttc tgcagatcag caaatcaact ttacagataa
     3181 atcggatcca gaagaaatca tgaaagcttt tggtatcagc aaaggagcat ttaagcgcgc
     3241 attaggtaat cttttgaaac aaggattgat tacacaagaa aacggtgtga caaaactagt
     3301 caaaaaatct aattgagaat cccttgcatg tttttcttaa ctagcttata ataattttaa
     3361 ttaacatagt gttatatctt tttttatttg taattattat aaattgttgg ggttgagtaa
     3421 atggtcatga atgctatttc ggcgatgaaa aaaacaaaac agcagctaca tgaagcgggg
     3481 tttaagctga caccgcaaag agaagctact ctgcttgtgc ttttggaaaa tgagaaagag
     3541 catttatctg cagaagaaat cttcttttta gtgaaaaaaa agagtccgga aattggactt
     3601 gctactgttt atcgaaccct tgaaatcttg acagaattga aaattgtcga taaagtaagt
     3661 tttaatgatg gattagcccg ttatgatttg agaaaagaag gcgccaaaca tttccatcat
     3721 catttactat gcttgaactg cggcacgatc gaggaagtag aagaggatct tttacttgaa
     3781 gtggagcaag tagtagaaga acgttatcat tttttagtaa aagatcatcg gctaacgttc
     3841 catggaatct gtcaggaatg ctatgaaaaa gaaaaa
//
LOCUS       DARBDN010000163         3823 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000163 DARBDN010000000
VERSION     DARBDN010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.168"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..1256)
                     /locus_tag="SCH06_002765"
     CDS             complement(<1..1256)
                     /locus_tag="SCH06_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEG1079281.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVV"
     gene            complement(1270..2487)
                     /locus_tag="SCH06_002766"
     CDS             complement(1270..2487)
                     /locus_tag="SCH06_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEG1079282.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(2477..>3823)
                     /locus_tag="SCH06_002767"
     CDS             complement(2477..>3823)
                     /locus_tag="SCH06_002767"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEG1079283.1"
                     /translation="IVDILGYSISPEYLFNVLADQAKQATFQLNDLNKAFVQLASTYN
                     QFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKKLNDVEVLGHDGDVIGDAYEFLISQF
                     ASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERRFFSVFDPTMGSGSLMLNVRNYLTHP
                     DNVKYHGQELNTTTYNLAKMNLILHGVDAEEMNLRNGDTLNKDWPTDEPYTFDAVVMN
                     PPYSANWSADTTFLDDSRFNRYGKLAPKSKADFAFLLHGFYHLKETGTMAIVLPHGVL
                     FRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGTSIPTTVIVLKKNRQTRDVLFIDASR
                     EFVKGKNQNKLSEENIQKILETYAERKDVEKYAHLATFDEIKENDYNLNIPRYVDTFE
                     EEEPIDMVHVGNDIKKIRQEQQVLEKELLEAISSLQTTPENEAWLQGALEVFKHEQ"
BASE COUNT         1053 a          826 c          647 g         1297 t
ORIGIN      
        1 actacaaaca cgatatgttg ccccattaat ttttggaagc gattggttcc ttttttctct
       61 tcctgtttct ttgcatattt caacgccgca tctagttttt gacgggttgt aatgatcaca
      121 acattcgcat tggcatctgc caacagagtt tcacttaact ctttggcact tcctgttccc
      181 acgatcaagc tattcgcttt ggcattacca gaagaaaccc cagtattaaa ctccgaagca
      241 aatttcgtaa actctgtggt ggtctgatta tctaaatctt tgcggtccac taacatgatc
      301 gttcgatcga tccccgattt tcgtgctaaa agcttagtag atacaaaact agtcaacgtc
      361 tttcctgaac cagtcgcatg ccacacatac cctgattgat gtttatttgc ggcaataaac
      421 aaggcttgaa tcgcatgcac ttgataagga tgtaacacca tgagggtttt attgtcttga
      481 tcttcactga caatcgtata atccgcaatc aagcgatggg catctgggat atttagcact
      541 tgtttgcaaa actcatataa gttttctacc tttttattat ctttcgttcg ccaactaaat
      601 aaaaacttag gatgcaaatc cttcggtaag gcatttgcaa aataccgagt cgtttgttca
      661 ttggaaacca caaacaactg taaggtcgaa aagatattgt tccgaaacat gccttcttca
      721 gcatattttt tgatttgatt aaacgcctga taaaaaccat cttttgcagt tacttgtttt
      781 agctcgattt ggataatcgg taagccattg atcaataagg tgacgtcaaa acgtcgatcc
      841 cgcgcttcta tgttacttcc acgttttgca atttgatgga ccacttcata agtagagatt
      901 cctccaccaa tgtcttgatt ggaataaagg ataagtgaga cagaacccaa ttgcggattt
      961 tcccgttcaa tcgtgatccg agccatccca ttttcacctt ttaaccattt cgcagcatca
     1021 aatggggttt tcgtccgtag caataattcg gttttgatcg tttcaaactc tttatcggtc
     1081 aaaggagaat cattcagttc tgcttgatta tttgagatga ttttttgacg taaattgctc
     1141 caaagatctt cttctgattt tagatccgga cgatacgtcc actgattatg tccttccccg
     1201 aggacacgaa tcaactgttc ttcgacttcc gcttcctcac ggtgactaat tttcattctt
     1261 cttccctccc taaacaaaca tcttttgcaa gaagcctttt ttcgtttcct tcagcaaatc
     1321 taacttacgt tgatgaagag cgatcgtatc atctagctgc ttgaagaagg caccaatttt
     1381 ttgttgttca tttatatccg gtggaaactg aaatgtcctt tgttctatac cacctttagt
     1441 cacatgtacc attgtcgttc cgttagttga ttctttaatt ttctctttat cagtcaatag
     1501 ccaagtatat agatactgtt tgtccaattc cttagataaa aatttaagtt tccaaatatg
     1561 ataatggtag attacacgtt cttcattcca catttcagga ccgaagcttg ttgcccataa
     1621 atataagaga tctcctttat tagcatactt gtcttcctct aattctaagt ttgaataata
     1681 ccatctatca ttagtattaa aattacctac tcttaaaacc ctatattttc cagaatcaag
     1741 taattcttgt tgtttaaaag ctctaccatt caaaaaaact accacttccc ccaacttccg
     1801 ctcttcccaa tctcccgtaa atcctggaaa acgaacttct ggcacttttg ctccgttttt
     1861 agggaacatt ttttgtaaga atcctttttt cgtttccttc agcaaatcta attcgtgctg
     1921 gtgaagcatg atggtgtgat caagttgttt gaaaaatgaa ccgatcttga tctgttcgtc
     1981 ataagttgga agtgagatag gtgtcttttt accactatca attgtatagg ttccgacggt
     2041 tccaatgcct gcaacgtcac ggatatactt ctgaattttg ttatttatga acgagtagta
     2101 aaagaagttt ccgtcaattt tatgctcatt cttgaaccaa atgatgtttc catccttaaa
     2161 gtaaattggg ttatcatcag tgattaataa ggggacacct attgatccga caccagttac
     2221 aagcaagtct ccttgagaaa ctttacctga atttttcgaa tattcattat atttttcttc
     2281 tgaaatgtaa agataatcgg atggttcctc attttttgca gctgagacaa tatcacgagc
     2341 acgtaaaaat ctaatacctg agttagtcca atctgattga tgaattcgct tcacagaagt
     2401 aacatccatc atatctccta acttacgctc ttcccaatct tccgtaaaac caggaaaccg
     2461 gatttctggt cgtgtatcat tgctcatgtt tgaacacctc cagcgcacct tgtaaccacg
     2521 cttcattttc aggtgttgtt tgcagggaag agatagcttc taaaagttct ttttctagca
     2581 cttgctgttc ttgtcgtatc ttcttgatgt catttccgac atgaaccata tcaattggtt
     2641 cttcttcttc gaaagtatcg acatagcgtg ggatatttaa gttatagtca ttttctttga
     2701 tttcatcaaa ggttgccaaa tgagcgtatt tctcgacatc ttttctttca gcgtaggttt
     2761 cgaggatttt ttgaatgttt tcttccgata atttattctg atttttccct ttaacaaatt
     2821 cacgactagc atcaatgaat aatacatctc gagtttgacg attcttcttc aatacaatca
     2881 ccgtcgttgg aatcgatgta ccaaagaaca agttcgcagg cataccgatc acagcataaa
     2941 tactgccgtc ttctaataat ttttgacgaa tgaccccttc tgcagcacca cggaataaaa
     3001 ccccgtgtgg caagacgata gccatagtcc ctgtttcctt caaatgatag aaaccatgaa
     3061 gaagaaacgc aaaatctgct ttggattttg gcgctaattt cccgtagcga ttaaaccgag
     3121 aatcatctaa gaaggtcgta tctgctgacc aattagccga ataaggtgga ttcatcacta
     3181 ctgcatcaaa tgtgtaaggt tcatctgttg gccagtcctt attcaacgta tccccattgc
     3241 ggagattcat ttcttcggca tctaccccat gtaaaatcaa gttcattttt gctagattgt
     3301 atgtcgttgt atttagttct tgcccatgat atttaacgtt atctggatga gttaagtagt
     3361 tacgtacatt taacatcaag gaacctgaac ccatggttgg gtcaaagaca ctaaagaatc
     3421 gtcgttcttt ttgatccaac gtcacgattt gtgccatcat atcagaaacc atatgaggcg
     3481 tgtaaaattc tccggctttc ttccctgctt ctgaagcaaa ttgactgatc agaaattcat
     3541 acgcatcccc gatcacatcc ccatcgtgac ctaaaacttc cacgtcattc aatttcttga
     3601 taacttcggt aatcgtcaca tttcgttgtt gctcatctgt tcctagtttt tttgattgga
     3661 gatccacatc atcaaataac ccattaaatt gattgtaggt agatgccaat tgcacaaagg
     3721 ctttgtttag atcgttcaat tggaacgttg cttgttttgc ttgatccgct aagacgttga
     3781 aaagatactc tggtgagatc gaatacccca aaatatcaac gat
//
LOCUS       DARBDN010000164         3712 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000164 DARBDN010000000
VERSION     DARBDN010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.169"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="SCH06_002768"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="SCH06_002768"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEG1079284.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="SCH06_002769"
     CDS             complement(2260..2511)
                     /locus_tag="SCH06_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEG1079285.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="SCH06_002770"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="SCH06_002770"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HEG1079286.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="SCH06_002771"
     CDS             3461..3679
                     /locus_tag="SCH06_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079287.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
BASE COUNT         1025 a          796 c          688 g         1203 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca ag
//
LOCUS       DARBDN010000165         3669 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000165 DARBDN010000000
VERSION     DARBDN010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.170"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            75..470
                     /locus_tag="SCH06_002772"
                     /pseudo
     CDS             75..470
                     /locus_tag="SCH06_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(465..683)
                     /locus_tag="SCH06_002773"
     CDS             complement(465..683)
                     /locus_tag="SCH06_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079288.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWKS"
     gene            790..1104
                     /locus_tag="SCH06_002774"
     CDS             790..1104
                     /locus_tag="SCH06_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079289.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1208..2386
                     /locus_tag="SCH06_002775"
     CDS             1208..2386
                     /locus_tag="SCH06_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1079290.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            2789..3082
                     /locus_tag="SCH06_002776"
     CDS             2789..3082
                     /locus_tag="SCH06_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HEG1079291.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1255 a          538 c          715 g         1161 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga tttccatatt
      481 tcgattttgg ttggcatatt tttcatgcca aattctgtga ttttaatagc atcggcaaga
      541 tttaattttt cttcagctct ctctccactt ttaagttttt ttactgtact caagttgatt
      601 cctgttccga atgctattgc attagccgta gatttttcaa gaatttcttt aattattttt
      661 atgtctgcaa ttccttgttt catattaaaa attcctcttt tctagtccgt tttgatggag
      721 tactggagtg tttttttaca attttaaggg gtaccgtggt ggtcgttttg attttgagag
      781 agaagggtga tggagttgga agttaaaaca aatgttaatt ctctggaaat agagttctat
      841 tcaattttac aaaaaaaact ggaagattac acggaaaaat tgcttgcagt cagtcattta
      901 cctctggtat taacaaatac tgatttaaag cgactatttc agataagtga tagtacactg
      961 aaccgtttag taaaacttgg tgagtttcct ccctgttggt acgggattcg aggacactat
     1021 tttcgtgatg atgttttaga atggatgaga aagagtgatt cgaatgacta tcgagaaaaa
     1081 ttgcgactac ttcgatcttt ataagttaca ttttctttct aagatgcggt acaatgatga
     1141 catagataga aagatttcca aagggtttct gcttgttggg ttccttcaaa ataggaggaa
     1201 tcaataaatg gaaaaaacag atcgattcaa gaagcaaatc agttctactg gtaggatcac
     1261 atggtacttt caagcatatc gaacaacaag acgtggcttt aattcaaaac gtgaggcgca
     1321 actcgcttat ctggaaatgg agaaacaaca aaggcttaag aaaaaaattg ttgcaagcaa
     1381 tgacaagttt agtgttgtag gtgagcaatg gttccaatat taccgttcgt taaatgaaca
     1441 aaaggaaata acctatgata agcgagagga acaattaaaa attattgttc gatggattgg
     1501 tgataaaaag ttgtctgatt tgacaccaga gtgccttcaa gaattgcttt ttaccttaaa
     1561 ggaatgtggc gttaatggaa caaatgttgg ctatgccaaa aatagtttac aatcacttat
     1621 tcaagttcta aatatgattt ttaaatattg tcaaagaaag aatttgataa gtgaaaatcc
     1681 aatgaagtct gtgagaatgc caaaatatca gttaacggta actgatttaa aagaagccat
     1741 aaataatatt gaggacaagt ttcttactgt cgatgaattg agaacttttt tgaattatgg
     1801 cattgttcat gaggaattac cgatgtctgt acttttccat gttctatttt acactggctg
     1861 ccgagtcagc gaggcgcttg ctctacagcc tggagatata gatttcaaaa gaaatgaaat
     1921 tctgttctat aagcaaacgg cagttaaagg taagagtaag gattttcgaa ttgaaactac
     1981 taagacagtt agttctgcta gacgagttct agtaactcct ctagttatgg aaaagctaca
     2041 acagttgatt aaggctttgg gtgagatgag gcaacattac aggtttatta tagaagaaac
     2101 atatttgttt gtgtatcttg attctagtaa acgtggtgtt ccttatcgtc gagagtatgt
     2161 aaatgatcac gtcaaacggt gcgtgaatcg ctcaggaatt aataagccat ttcatactca
     2221 tttagctcgt catacaatgg caagcttagt agcggaacac tgtagctggg aagtcttgaa
     2281 agatcgctta ggccatactg accaaacaac ttcgaaaatt tatcgccact taacgtcaaa
     2341 tgaaaaggta aaacctctga ttgcttttag ttctttagag agttaaaaaa acggtgaaag
     2401 cactggtatt acaggattct tgaaaaacga ttttttaaca aattagtcaa tatgtagtca
     2461 gaggtaataa aaatcctttt atatcaatac tttaacgact tttcacaagt atcaaagaaa
     2521 tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa gggttctttt
     2581 ttcttagcat gtaatttgaa caccctgatc cagttttttc tttaattatt ggtaggggag
     2641 aataatggat tagaataaat ctacctataa gtagtagtaa aaaaaagagc actatgataa
     2701 tatctttctt aagagtaacc gctttaataa aaaatccaga atattctaac ataaatggag
     2761 tattcttaga atcaaaagga gaaagaagat ggtttatact tatacggagc aagaaaagat
     2821 gaaagtttta gacacattca tgaatgatgg aaaagtaaaa caagtaccaa gttcaacaaa
     2881 aaagaaatac atcctattga aagaagtctt gaaacgcttt gaccatggag tgacttatac
     2941 agaaacagag gttaattcga tactgctgaa cgtattttct agtggcgatt atgtcgaaca
     3001 aagacgttat ctaatcacat ttggcttttt caaaagaagt tcagacggtc gggcatatca
     3061 gatgatggga attgaaaatt agaagtttta atttatactc attgaaaaaa gttcaagtat
     3121 gcgatattgg ttctacaccg catacttgaa ctttttttgt catctgtatc tataatacaa
     3181 agccaagaac gttattcaaa atatggatag ctatgataaa agctaatgag cgattcgcag
     3241 ttaaataagc aatcgtcagt aaaatcgttc caggagcgta catgaaaaaa tcaattggat
     3301 gcgttacatg aataaagata attctctttt atttgtacga ataaatacca aaacgtacct
     3361 cctaaaatta gattttggac agatgccctt taaaaagata acaagatttc gttcttgaaa
     3421 caatatatat gcttttattc caatgaggtt gtgaaaacag tattttgtcc tgagcgttag
     3481 aaaattgaaa atggggaata gcaactcgta ctttaccatt ttttaagtga atacaagatc
     3541 agctaattga acaccgttta ttcgtgatga gggacacaac actgcagtcg acacatttct
     3601 cttttatgtt caaagataac aaatatttaa aacaaagaaa aatagtagat aatcccgtcc
     3661 taactcttt
//
LOCUS       DARBDN010000166         3651 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000166 DARBDN010000000
VERSION     DARBDN010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.171"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            175..411
                     /locus_tag="SCH06_002777"
     CDS             175..411
                     /locus_tag="SCH06_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEG1079292.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            430..645
                     /locus_tag="SCH06_002778"
     CDS             430..645
                     /locus_tag="SCH06_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEG1079293.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(1348..2100)
                     /locus_tag="SCH06_002779"
     CDS             complement(1348..2100)
                     /locus_tag="SCH06_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1079294.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(2115..3362)
                     /locus_tag="SCH06_002780"
     CDS             complement(2115..3362)
                     /locus_tag="SCH06_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEG1079295.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(3438..3584)
                     /locus_tag="SCH06_002781"
     CDS             complement(3438..3584)
                     /locus_tag="SCH06_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HEG1079296.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
BASE COUNT         1245 a          578 c          535 g         1293 t
ORIGIN      
        1 ttccacaaaa actttgaaaa cagttcttga acactaactt tttcattcct gaatcaaatt
       61 tattttggaa attttactat tcaagaataa acttgataag tttcaggaag atttttactg
      121 ttaatcaaat acgtatgtta cagtagcacc gtaaaaaata ttatttaaag aagcgtgttt
      181 aaacatgcaa aatgtaaagg aactaagtat tgtggaaatg cacaaactgt tggtggaggc
      241 aataatgctt ggggaaaatt ggggcaagtt gtaggtggac ttaccacagg ggcagtaggt
      301 ggtgcaggtt taggaacagc aatttgcgga ccagcttgcg gtgttgttgg agggttatat
      361 ggagctgtcg ctggaggtgc tgcagctggc tgggatgctc gaaaaaaata aaaaaggaga
      421 ataagtagta tgcatattaa aaacacaaaa acaacattta tattatcttc agaagagttg
      481 aaaaatattc aaggtgggag tgccgtggga gttttaggca ctactttttc tggggcaaca
      541 gcaggagtaa aactttgttc agccggagga ccttatgcaa tagctgcttg tggtgtaggt
      601 ggagctttat taggtgctgg attcagcatg tggaccggtg cgtaaacaat taaaaaatat
      661 caaacctcaa gattggtttg tgtcgattac gaacataggt atgttcttta tcttttcaaa
      721 agtttggaat ggacagaact ttttactaaa gcttcttgtg ctagttttta taattatatt
      781 aaatttttat cttttattaa agtcagataa aaattctttg gaaatgtaat ggtagagata
      841 tttttacaaa aggacttgca gcgctgtagt tggtgctgca ggaggaccta tttcggccgt
      901 tacaggaggt attggtaatg tacttgtcgg atgtgcatta aagcctgttc ctgcaagtta
      961 aatttataaa aacaggaaag taattatctc aaatcctatc aagtacaatc ataggattgc
     1021 acttgacagg acaaattttt taactaaaaa atgaaaaaca ctttctaaaa attagtagaa
     1081 tttgccaaat ctttcgcatc ttccaccata catttaattt taattcccct ttatggtact
     1141 taataaaaac aagaaaagaa ctattcattt ggcccttttt tggttccaga ccatagaaat
     1201 attcctccag taactaatat tgctgttatg cacgtaacta ataacagcta taaaaattgg
     1261 tacaacttta ataggattca gaaaaatttg cactagtgaa ggaatctatt ttattagaaa
     1321 aatgcaatct ccctaaagaa aaaaccacta aacagtgctt tctttcaact tctccttaat
     1381 tttttgtgct ttccctaaag taaagtttct ggccaactct gaatcaaaat atagtgaacg
     1441 ttttttaaaa tctatttctt taacgttaaa gatatttact aaacacgctc gactaattct
     1501 tgttaacata ggatatttct tttcaagctc actaattctt ccataaaatt cgtactgccc
     1561 atctttagta cacaatgata atctatgtgg taattttgaa gcttctacaa aataaatgtc
     1621 atttatatca aaagtaaatg tttgagaacc tatggaaaaa acaaatgctt gattcgtaac
     1681 ctgttttgtt gcatctatcc tttcttgcgc taataacaat aactcaacaa tctcgtttcg
     1741 atactcatct agtgtttgat cttttgttac aaatcctaac gtttcaactc ttctttttat
     1801 tgttacgggt aacatctcat catgagtagt tgtaaaaatg atttttgctt gaacatcata
     1861 ttttctgatt acttctgcta attctatacc gttaacttca tgatttaaat caatatctaa
     1921 gaaatatatt ccttgctttg gtcggaattg tttgaggtat tttttaactt ctaacggact
     1981 ttgtgttttc aatactatct taaatacttt atcgtgaaaa agaatgaaat tatcaataat
     2041 tcgttctaac tgatttaatt gtataatttg atcttcacat aatattattg gataactcat
     2101 aaatcctcct tccctcaaaa caacaaaata acttgagtag taaattgata cggatcgttt
     2161 tgatagttca caaacatatt gggattcttt ttattgattt cctctatact agataaacct
     2221 aacccttgat gtcccttttt tgttgttatt ccttttttca ttagagtatc tatagagagt
     2281 agtatctctc tacaactatt cgatatcgaa atttctatct gtttatcatc tcggtaaata
     2341 gctagagaca gttctctatc ttgactctct atagatgctt caattgcatt atcgagaata
     2401 attccaagca ccctaataca gtcaaatatt ggaacaggaa cttcaataat agtacttgga
     2461 cattcgaatt tacaacaaat cttattgtta tttgcttggt atagcttcgc tatcaacaaa
     2521 cttttcaaat attcattttt tatatttttt aaataacgat attcaaactt attggttaga
     2581 taagaattag aatagatctc taattctttt atttcttttt ccaatatcga atcatggttt
     2641 tgattagcga tttcttttaa actcagcaat aaatttttat agtcatgtct aaatctggca
     2701 aatttttctt gatctttttc cagtgaatca gtatattttt ttagataaac caattctttt
     2761 cttttcaatt gctgttcata ttgttctcgt tgcctaatag ttattctaat aaataaaaat
     2821 agaacaacaa acatttgaat gattaaaaat attaagacac caaacacaaa atgatcaaat
     2881 acttgatatt gatgagcaac ataagaaaca aataaaccaa ttgtaagtaa ataaatcatg
     2941 aatatagcag taagtttaga actggactgt tcaacaatcc tatttatagc taattttcta
     3001 tataaccaaa taaacatcag caaaaacaaa gaatcaagca ttatctggaa tactacataa
     3061 ccataccctt ttatcccttc aaatgaaaac atatacgtca taaccatgga agtaataata
     3121 gatctgaaat catcaataag catacataat agtaatttat ttaaaagcac tatattagtt
     3181 ttcttctttt cctttaatat aaaataactt ccgattatag gtatagctgc ggaaacatca
     3241 gtaaataatt caacaaaaaa agtgagtggt atcaataaac atacaaaaag atattttctt
     3301 ttgttaagat cagtattagt catataaaat aagagaaaaa agaaaaagtt tcccacgaac
     3361 attcttaata gataagcttt tgtatcgata gtaatcaaga gatcccctcc tgattttagg
     3421 atatcataaa aaaaatttta gttacacttt ttaaataatg aaaaaacaca ttccactaaa
     3481 tttgatgccg gttttccttg aggttttgtt ccagcacctc ctttaatttt tttaagctct
     3541 tgatctgaac attgtttagc atttagtcta tttttttctt ccattacgat tccccctaca
     3601 aactataaat acttttatgt cactgattca atatacctat ttttctaatc a
//
LOCUS       DARBDN010000167         3643 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000167 DARBDN010000000
VERSION     DARBDN010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.172"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(131..715)
                     /locus_tag="SCH06_002782"
     CDS             complement(131..715)
                     /locus_tag="SCH06_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079297.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(926..1129)
                     /locus_tag="SCH06_002783"
     CDS             complement(926..1129)
                     /locus_tag="SCH06_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079298.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1139..1561)
                     /locus_tag="SCH06_002784"
     CDS             complement(1139..1561)
                     /locus_tag="SCH06_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079299.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1799..2413
                     /locus_tag="SCH06_002785"
     CDS             1799..2413
                     /locus_tag="SCH06_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079300.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2578..3402)
                     /locus_tag="SCH06_002786"
     CDS             complement(2578..3402)
                     /locus_tag="SCH06_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079301.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3426..3581)
                     /locus_tag="SCH06_002787"
     CDS             complement(3426..3581)
                     /locus_tag="SCH06_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079302.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
BASE COUNT         1208 a          636 c          518 g         1281 t
ORIGIN      
        1 atattaacaa atgaataaaa tccttacaac atttgagaat aagttatcag tagacactta
       61 caaaaaattc tcatactatt gtcacttttc tagataaatg gcaaaaattt tcagcattaa
      121 atgacaaaaa ctaatgagaa tttgtctttc catttttctc ctccattttt gccaaataac
      181 gataaatggt ggttcttgag acgttccacc gttccgcaat agtcttaata ggtgtaccgc
      241 tatccactaa agtcttcagt aattccaaat cttgttcaga caatttttca ggacgaccac
      301 caaaccgtcc tcttgcacga gcagctgctc gtcctgctgc ggatcgttcc aggatcaaat
      361 tacgctcaaa ttctgcaaat gccgcaaaca aatgaaacat gagctgtcct gtagaacttg
      421 atttgtccat cgtaatattt tcttgaatac tatgaaaact cacaccacgc tcattcagtc
      481 gattgacgat tgaaatcaaa tcttccatat ttctacctaa acgatctaag cgccaaacga
      541 caagtgtatc gccagagcga acaaaatcaa tggccatttc taatcctggt cgattacttt
      601 ttgccccact catatgatca gtaaaaattt tttcacaacc aaatttattt aggctgtctt
      661 cttgtaaatc caaattttgt aaaccagtag atacccgggc gtatcctatt ttcaaaaaaa
      721 tcactccttc attaatttta ttgtaacata actttatcca tatagtttaa ctgaacatag
      781 atattgttat gggtttatga acatgaaatg aattgttttt ttgaaaaata aagcaaaaaa
      841 agaaagtgtc cagaaatggg tgattttatg aacactttca attagaaaaa aagaatgtcg
      901 actagacact ctttttttaa aatcattatt tttctttttg atatgttttt tggtctcttt
      961 tttttctttt ttcttcagaa tcttctagat tagaaattga tttttgaatt ttttgtgtct
     1021 cctgtaaagt tcgctgaact tgtaaagctg attcttcttt cggtaaatta attttactta
     1081 gaatatcgct atcttgataa aaatttggtg tgttcacaaa ttctggcata aaaaatccct
     1141 actttctagt taaggttcct gaataagtcg caatccaatt gtttccagct gatttataac
     1201 tttgtaaata caattttcca tagtaccaat aaccatttct tttttctttc caattccgtg
     1261 attgaggagg tctagaaggc caaccaactt tatcaaaaat catcgttcct gtcactcgta
     1321 tcgttttaga agctgctaga gcaagtaatg gagaaactat taaataattt tcagtaacag
     1381 ttaagtcgtt agttgggtta ccaatggcta ttccgtccct atctaaagga gttaattctt
     1441 ggttattatc tactacagta gttggttcat ttgtactatc agcaaatgta ggaattgtag
     1501 ttccagttac actaattcca atagttaaaa tacctaaaga taaaataaac ttatttttca
     1561 ttgtctatca cctcgaaatc aaaactaaga aaacgttttc ttaataaatc ttaacagata
     1621 aatcaagtta tatactagaa aattcataaa atatattttt aatgtcataa tcgtttaaat
     1681 tttcttgatt gacatttatt tacaaaaaat attgccattt aaaaagaaaa gtgacatatg
     1741 gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg taaaagtttt
     1801 gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc agattgaaga
     1861 aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg caacgattac
     1921 tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata tttttattgt
     1981 ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag tcaattactt
     2041 gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg aagcaattgg
     2101 caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg ccatgatcgc
     2161 tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga tcgcaaaagc
     2221 aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag atccccaacg
     2281 tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga ttgctaagat
     2341 tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag acagcatggt
     2401 caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat ttcctacata
     2461 taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa attccaacaa
     2521 accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt atttacgtta
     2581 atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct tattatcttg
     2641 tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa ttcctatagc
     2701 tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt gagatttatt
     2761 tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca taaagctatc
     2821 attaatttta taaaaaaaat taaatgtttt tagcactgcc atataacatt caaaacattc
     2881 ttctatagtt ggtttacttc cttgaggaga atgaaccaat ttattacgtt tttctatgaa
     2941 atttttaatt tcctttctta tttctttcgg aaactcaata ttaaagtacc ctttaaacat
     3001 gctccctaat aatttgtcta cagggggaga ttgtaaattc tcaaatatta gagttaaatc
     3061 aggtttctct tgttgataaa attcctttac ccctatttca caggctgtaa ttatcgaaat
     3121 aaacctatct ctagtatttg atatattttt acttctttta aggagtataa gagaaaaggg
     3181 gatactttcg tgtccatgca tgtaattaac taattgttga gcttcagaag ttatatctct
     3241 aattatatag ttaacggaat taggaagtgt ctttaactct aatgaaattt ctatccaatt
     3301 actatcttct aatctgtata tgctcgaagt ataatttgat tcgtcagcaa gcatcgctac
     3361 atcccaaaca ctgatcataa aatcttttaa acgttcaatc atttcagcaa tattgctaaa
     3421 atcagctaat ttttctttag aataaaaaaa acatttatat cagaatcaat aaattctatt
     3481 ttttttatta ctatatcgtc atcattatct tgaccattta tgtttattgt tccctgagtg
     3541 gggagtactt ctttcaaatt caagttaaat ttatattcca ttacttctcc tccaatatat
     3601 aaaaattact taactgtatc caaatttaat atgtaaataa atc
//
LOCUS       DARBDN010000168         3593 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000168 DARBDN010000000
VERSION     DARBDN010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.173"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            342..1382
                     /locus_tag="SCH06_002788"
     CDS             342..1382
                     /locus_tag="SCH06_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEG1079303.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            2206..2538
                     /locus_tag="SCH06_002789"
     CDS             2206..2538
                     /locus_tag="SCH06_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEG1079304.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            3157..3498
                     /locus_tag="SCH06_002790"
     CDS             3157..3498
                     /locus_tag="SCH06_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEG1079305.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1326 a          473 c          670 g         1124 t
ORIGIN      
        1 aggtagtata tattactagt aatggtagta tgttttatat gcataaggta gttcttaatt
       61 tattttttgt tttgacactg gtagtactta attatcttta attttaaaac taaattttat
      121 tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt agttcttaat
      181 gactttaaag gtagtacata attcatttta tttctgattt taggtagtat ttaattaaaa
      241 aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa agagtaggta
      301 attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat tttaaatttt
      361 ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc tttattgttt
      421 ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt ttaaaagcaa
      481 gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt tattttactt
      541 atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg atagcaatca
      601 aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt aacaaacagt
      661 tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca gaaaatgata
      721 tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa tcagagggta
      781 tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg gctcaagagg
      841 gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa atcataccag
      901 aacttaataa taatatatta gacactaata gacacaatat agacactgaa aaagaccgcc
      961 tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac agcattgcta
     1021 cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt tacagtgaag
     1081 ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata gaaagtggta
     1141 tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa gaattataca
     1201 cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat atccagaacc
     1261 tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct aaagtatcaa
     1321 gtgaaaaacg tttgaattat gaaagctccc caagcactat tacgaaagac tggttagagt
     1381 gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt aaaaattttt
     1441 tattattcta attatattac gaatattaca aaataatagc tattttaata gaatttataa
     1501 gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt gttaaaagaa
     1561 ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt tttttgagtt
     1621 ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat cttgatatta
     1681 cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat ttaattgtct
     1741 gctatgcttg tgatgaattg attttcgttc tgcacttttg gatgataaat ttggacaatt
     1801 gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct tcgtcagcgt
     1861 tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt acggtattac
     1921 ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt ggctgtgtta
     1981 aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcacaatgtt ataaaaatgt
     2041 ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat gtttggatgc
     2101 gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga aaaataacaa
     2161 gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc atatacagga
     2221 attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac agagaaaatc
     2281 acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa atatataatc
     2341 cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa gcaaataatt
     2401 ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt ttatgaccaa
     2461 aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc aaaagggatg
     2521 gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt ttttcgcttg
     2581 cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa taaggagtag
     2641 acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac gattggtaac
     2701 gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa tgaatttgtg
     2761 taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt tagaatagcg
     2821 tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac tcatggaata
     2881 aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg tgctgcagta
     2941 catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac cgctgtctac
     3001 tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat ttttaagtaa
     3061 acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga tataaaacat
     3121 agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga tccgaatata
     3181 cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa aggatttgtg
     3241 acgtttagaa gaggcggaaa ttgtaaagga ttagatgttt tagcattaga cgaggatgat
     3301 ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc tgaagatgat
     3361 gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga attatctgtt
     3421 gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat tgaatttgta
     3481 gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc ttagaaggag
     3541 tcacgatgat taataaaaag gtagtattac cttaggcatt gagtaaggaa ttt
//
LOCUS       DARBDN010000169         3558 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000169 DARBDN010000000
VERSION     DARBDN010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.174"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1223
                     /locus_tag="SCH06_002791"
     CDS             <1..1223
                     /locus_tag="SCH06_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1079306.1"
                     /translation="EFFANVLETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSL
                     NVTNVKTGIKSIVLAHGYSTASSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQF
                     LGDYRTDSGLILLVDMGSLNQLGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSI
                     TEIGAEIETSLTFKKQLLLPKKKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELV
                     IIPYDYKKLLENKNFETPFQLYDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHY
                     LEKELTIEVNDLQKELIFNFSISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSN
                     NQLFLLYLHCSCMIERIVRKESVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEI
                     PDLELRLLSDIVQG"
     gene            1236..1868
                     /locus_tag="SCH06_002792"
     CDS             1236..1868
                     /locus_tag="SCH06_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1079307.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            2767..>3558
                     /locus_tag="SCH06_002793"
     CDS             2767..>3558
                     /locus_tag="SCH06_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079308.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         1192 a          536 c          696 g         1134 t
ORIGIN      
        1 acgaattttt tgctaatgtt cttgaaaccc cttattggta tgcaaaaaaa atcttaagcc
       61 ttttatctga gtgtttagat caacctgtgt atgaagagga cattttcttt attacgctat
      121 atttttatag tttgaatgtc acgaatgtta aaacaggtat taagagtatt gtgctagctc
      181 atggttattc tacagctagt agtatggcga atgttgccaa ccgtatgctg aataagaacg
      241 tttttcaagc ttatgatatg cctttagata ttacattaga gaaaattgaa gcaaaattga
      301 ttcaattcct tggagattat cgaacagatt caggcttgat tttattggta gatatgggtt
      361 cactaaacca actaggcggt ttattagtga atcatctaaa tggaccactg ttaatcattg
      421 atcatatcaa tacaccgtta ttattggaag tcggccaaca agtattaaac aataaaagta
      481 tcaccgaaat aggagcagaa attgaaacaa gtcttacttt caaaaagcag ttactacttc
      541 ccaagaaaaa gaaaaagaaa gccatcatta cttgttgtta tacagggatt ggtagtgcga
      601 cccagattca ggagatttta acgaaatgct tgaaagatgc agttagagaa ttagtaatta
      661 ttccgtatga ttacaaaaag ctgttagaaa acaagaattt tgagactcct tttcaattat
      721 acgatgtcat catgattgta ggtacagaag atcccaaaat taatcagatt ccatatattg
      781 gattagatcg cctgattaat gggggaagca ttggcgaatt tgttcattac ttggaaaaag
      841 agctgactat tgaagtgaac gatttacaaa aagaattaat tttcaatttt tcaattagta
      901 aaattgtcga aaatttaacc attttggatc cagataaggt gctatctttt gtacaaaaag
      961 caattaaaga attatcgaag ttattaaatt ttgatttttc taataatcag ctgtttttgt
     1021 tgtaccttca ctgtagttgt atgattgaac gaattgtacg taaagaaagt gtggatgagc
     1081 aagaggacat tgaagaatat atgcaagcaa atggagaaat aatggataaa attcatagcg
     1141 ctttttttga gattgaaagg gaatacacaa ttgaaatacc agatttagag ttgcgattat
     1201 tgagcgatat tgttcaagga taggagtgaa ttcgaatgac aatgggagta atttttgata
     1261 tggatggggt actcatagac agcgagacat tttattttga gagaagaatg aacttctttc
     1321 aagaactgga gatagatcca ggatcaaacc agattgatga ttatgtgggg aaaacagaag
     1381 ctgcaatatg ggaaacatta gttcctgagg acaaatcatt aagagaggaa ctttatccga
     1441 aatatgtaga ttatcgaaaa acgcatccaa ttgatttcgc taaagattta cgaaaagaag
     1501 tgaaaccgtt acttgacttc ctcaagaagc gggatatacc attggcactg gcatcttctt
     1561 ctccagttgt tgagatagag agtatgctca ttcaatgtga acttactgaa tatttttcct
     1621 ttgttataag tggtgagtca ttaaaacaaa gcaaaccaca tcccgaaata tatttaaaag
     1681 cgaaacagca attagactgt gacttcttta ttgcagtaga ggattcaacg attggtatta
     1741 aatcagcaaa ggcagcaaat atctatacgg tggcactaaa acaaccaatg caaatcgatc
     1801 agagtgaagc agacatacaa attgaaagtc tacaagaact ggaacaaatt gttttagaaa
     1861 aaggttagtg aattaatgga aataaggcta tatatctgtg ctagctattt tgactaacca
     1921 aaaaaacttg ctataattca ggtgtagtaa aaggtgctgg taacaccttt tacgaaaatg
     1981 cttcggcagt gataatggga ttggcttttt aagtttttta ttttgctcgc aatccctaag
     2041 gtcatgtgaa tgatcctagg gattgctaga atattttgca acattctatc tatttcagaa
     2101 cgtaaccttc cccagttcat tgggattcat tagcatacaa ccaacatttc aaaaagaaat
     2161 tgcactacac cattattagc tattttgact aaccccaaaa aacttgctat aattcaggtg
     2221 taggtaaaag gtgctggtat caccttttac gaaactgctt cggcagtggt aatgagtgtg
     2281 gcttaaagga ctagtccttt aagcttttta ctttgttcgc aatctctaag atcaagttaa
     2341 tgatcgataa gattgctaga atattttgca acattctatt tcagaacgta acctttccca
     2401 ttccactgtg attcattggc aaccctcctc acaaccaacg tttcaaaaga aattgtaaag
     2461 ttgttggggt accacgaccg aacaatacta cacctgaatg atagtaagtt gtctcattaa
     2521 gtatagcata tcctcttttt gggtaaatag aaatcggtta cattttttat ccaagaccaa
     2581 gttttttcat ttggtcttat ttgctatacc caaacaattc cgcagtatag tcgacggtat
     2641 tgattttatc aggtgagtaa tagaaacttg ttttccttcc ccaaaacatt acctataaag
     2701 gagaaaaaat ggtatcgtaa ttatataggt ataggatgaa atttttttct aagaggaggg
     2761 ttgttgatga aaaatttaca gttaaaattt attgttgatc catcgattgt acgctggttt
     2821 cggattatca atcaatttga gcgcaatcaa cttgccacaa aaggagaatt agcaaagagt
     2881 aatcatgtat ctgaacgaac cattcaaaca gatgtcaata aaatgaagga ctacttttct
     2941 gaaagtgttc aatttgtttc aacgaaaagt gggtattctt ttcagaagga aagaccggtt
     3001 ctttttctca agcagaagga gcaactactg gagaacgaaa ttttatttga gttgttaggg
     3061 aatgtctttt atggcgaatt ggaagatatg acggagctaa ttgatcgttt tcatttatct
     3121 gaagcgactt ttcgtcggta tttgaagcag attcaaccag ttttggaaga atacggctta
     3181 gaattgagtc tttatcctct tgatttaaaa ggagaagagg caaatattcg caagtttttt
     3241 aaagacttct attatgaggg ggagatgacg ccccatactc ttgttccacc aagggatctt
     3301 catgaacttg tgcaagctac attctatgat aaatttgagt atttctcgat tggaacaggg
     3361 acttctcctg ctgaatttta ttatagtttg tatattgcga ttgagcgtgt gagacaagga
     3421 aaaacgatag ccattcctca aggtctgatt gagcgagtaa ttgctagtga gaattttcgc
     3481 ttaatgtatt ccttgaaaga agcgattcaa acaaattatc aagttgcttt atcagaagag
     3541 gagttttgtt ggttgtat
//
LOCUS       DARBDN010000170         3498 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000170 DARBDN010000000
VERSION     DARBDN010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.175"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..2177)
                     /locus_tag="SCH06_002794"
     CDS             complement(<1..2177)
                     /locus_tag="SCH06_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079309.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVL"
     gene            complement(2849..3117)
                     /locus_tag="SCH06_002795"
                     /pseudo
     CDS             complement(2849..3117)
                     /locus_tag="SCH06_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1000 a          768 c          540 g         1190 t
ORIGIN      
        1 aggacttcac cactgccttc agcatgttta attagttcaa caccacccgt atcaaggatg
       61 ttttcaatgg ttaacgtcac ttcttctatg gagtattcat ttataaaaac atcatgtacc
      121 gtcgcatcta aaagataccc ttccggtgct tctgtttctc ggacttgata gctacctaca
      181 ggaagcggtt cacttaaaaa ttctccgttt tctgccgtta taccttcttg tatcacttgt
      241 gaatcgcttg ataaaatttc aaattttgct cctgccagcc tttggccatt ctcatcagtt
      301 ttaattactt taatacgccc atcgattttc cttgttctta cagtactcgt attcaatcga
      361 ttgtcactat tcacaagcgt tgcaaagttt aaaatttgat cgccgaccgc atacgcctct
      421 acattgacct taaaagagag ggtaaaactt gtcggaccac caatcgtatt attcgcactg
      481 aaacgaacta ttccattatt gacttcggca tcaatgaaag agggaatatc tgatagaaat
      541 gacacaaatt ccatgccttc ttccaaaaca tcttcaataa caagcgtatt tcttgttcca
      601 gaaaacatcg agacatgcag agtatacgtt agttcatttt cattgagatt gataacattt
      661 ttgtccacac tttttcttaa agagattgcc ggaagattac tttcagggat tctcaagcgg
      721 tagtctcggc tcattacctg attattgtag gtcatactcg ctcgattccg agaaaaccca
      781 tcctcttgtc ttccttcatt gaacaagtcg acatcggtca cttcaagagc atattcaata
      841 aaatacgatt gaccctctgc tagattacca aagtccacaa caagtgtatt cgtttcctta
      901 ttaaaagata ctttgtccac aaattcctcg gaaacataat gagttctaac gtttgcttca
      961 cctggattcg ttacttctgc gatccgaacc ccacctgaaa taggttctct atttccagtg
     1021 gaactccatg tagtcggatt cggtgccaaa gttgttcctt gcggtagtac atcggtaacc
     1081 actacaccgt cttttcgtga tccttcataa tttacctgca aaataaattt attactgttg
     1141 gtcacgtctt gcccgtcaat cagcagattc ccaagatttc cttggctgtc gatttctcta
     1201 gagccatagt ataatttcga aaaaatgggt cttgatgaag gaataggcgt aattgaaaat
     1261 tccgtgtttg ctgctcgctc agcataagta agactcactt gaaagtcatt atttggctca
     1321 gtaccgcctg attgaaagaa agcaacttca aacgtgatac tgaatgtata cgactgagcg
     1381 gcttcattta atccttcata atcaaaggta aatggaaaaa caacgtctgt gccttcttgg
     1441 taaaatgcca gtggctttaa aggtgaatca tcagcgacct ccactctaat gaactcaatt
     1501 aagccaatcg atgctctagg aactcgtacg accatctccc catattcttc aagaatatcg
     1561 ccagcgcctc cttgaatgta tccctttaac gtttgtgtat gcctgctcgg caaagtgggg
     1621 cgctcagcag agatgccgat gtcataattc aagagctcct cttgtctttc aatctgagat
     1681 tcctgcgtta tagatggctc agatgatctg gcttcattaa aagattcact taagctttct
     1741 tctggtatat taaaagattc acttgtgctt tcttctggta cattaaaaga ctcacttgtg
     1801 ctttcttctg gtacactgat ttctattgag accgtatttg attgaatatc accgcttctt
     1861 gcggtcaatt cgtatttacc tgaatgctgg gaagaataag taatcagacg ttcgtaatca
     1921 ttgagttgct tcacttcccc ttcaatcaaa tcctcactct tatcaatgac caatgcattt
     1981 agcaggtctg gtgttcctct gactcgcaac tggaactgct cacccaaagc agcctcctct
     2041 tgatcaactt cgatcgtcag cgaacgctct ggctgttctg ctaaagactc agctagaacc
     2101 gttatgttcc caaattgatt gatcacaata agcataacta gaaacatact taacagttta
     2161 tgaaatttgt tcctcactat tactccccct tataattttg actaaacaac aaggtacccg
     2221 ataattttct aaaaagattc cccaactcaa aatggctgcg ttacctccct cgtattttcg
     2281 gttcaactca agcgttgcaa tgtaagctgt aaacaaagct aatgattgcc gattgtcttc
     2341 tgttgattga ttcgatagct ttgtatgact tttagttgtc cgtgtggctt aaccataatt
     2401 atgatttcac gattcctcct gccagtgcct tgcacaagct ggagcgtaac cctaatagtt
     2461 attttgttaa tgtacttata tacttttata cttttccatt agaaacaatc actaaatcgt
     2521 tgataccaag gtcagactct agaatttcat cagtgaatcc ctgtattggt taaccttcat
     2581 caatcccaaa aaaatatatc aatgcttagc atcaaaatga atatatagtt tagaatactt
     2641 gggattcatc gataactgat cgcttatttg gccatattat ttggcacttg gttcaactaa
     2701 acgcatttag gatgttcctt cattctcgtc atggatgttc tcaaaccgtc attactaata
     2761 aactgtccac cgaatcgatg gttcatttct tgcattttcc acgtccaatt actctttttg
     2821 ctctttattt gggcgtagtt tcactttctt aacttgtatc gtcttccatc aactccttaa
     2881 tcatcttctt agctttattg gctcggtttc cttgtaaaag gtatctacaa atagtgacaa
     2941 tctgtattaa atcttcatca ttttctgtaa tgtcaataat ttctatattc tgtaccatat
     3001 attgcaaagg gtttcactaa gttcataacc gaagcgaatt aaacaacttt tgtatagaat
     3061 aactaccttt tctatttttc cattggtaat tctatctatt aattggttta atccttttgt
     3121 tgtagttgat tccactacca agatgattct ctcgaatttt aaagcttgaa gatgtattgc
     3181 tatttttgct aactggcgta tttgcaacta tttttccctt ctattcttcc ttcattgatt
     3241 cccctctaaa attactatcc ataaaaaatt gcataaatga caatagtatt tatattagtc
     3301 atactgcttt ttaacacagc aaattccaga aaaacattcg ttacatattt gtgaattttt
     3361 ccaaaaaata acacttttat aaaacgacga aaaataaatc actaccagtc aacttctata
     3421 atattaccaa ataacaaact aactatccat caataacgtg ttttattttt taaaatttct
     3481 ataaaaaaac aatcattc
//
LOCUS       DARBDN010000171         3308 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000171 DARBDN010000000
VERSION     DARBDN010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.176"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..2015
                     /locus_tag="SCH06_002796"
     CDS             <1..2015
                     /locus_tag="SCH06_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEG1079310.1"
                     /translation="ESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNSE
                     SQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDYE
                     FYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVYV
                     DALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIGE
                     NINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIYL
                     ALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVHL
                     AEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNGL
                     LFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRIQ
                     RKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEIE
                     FLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGWF
                     AIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSAS
                     LKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2012..3265
                     /locus_tag="SCH06_002797"
     CDS             2012..3265
                     /locus_tag="SCH06_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEG1079311.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILIVKLS"
BASE COUNT         1252 a          448 c          553 g         1055 t
ORIGIN      
        1 aagaatcaga tttttttcat ggaattcaaa atgggtggca agggcattgg attattatct
       61 ctgcgacatt tgaaggaatc agcgaagaag aatttgacaa tgagatttgt gcttccattt
      121 ctttaaattc tgaaagtcaa acaatcttag aagaattgat ttcaaatgca gataaaggtg
      181 taggtagtat ttctctattt attagaccta acaaagctat tagaaagcaa ttatttgata
      241 tttccactga attagactct catcaattta acgaatttag aaattctatt cgtctatccg
      301 actatgaatt ttactacaca tctaaatcaa atctaaattt ctgtatcaat gaaaattatg
      361 ataaattggt aggaagactc aatgacaata tagctagtaa tcctgaagaa gacgatgaag
      421 ctctgttggg ctcaagaatt gacatgtcag atattttcaa gcatatttcg gttgtttatg
      481 ttgacgctct tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca gtcaaaagaa
      541 tcatggaaac aattgaatca aaaatatcat cagataatgt tgagtcatta aaaacaatta
      601 tacagcaatt aaatgagact attaccagtg ttcctgaaat taggaaaatt ggcgaaaata
      661 ttaatcggca actaaatagc ataattggtt cagtgtattc tcctaatctt cttctttcct
      721 caactatgtc agatgatatg ggttctttag caaaatttct ttcaatgaag ccagaacaaa
      781 atatcgactt agacttacta gggttaggac atctaaatat gatttattta gctttgaaaa
      841 tagtcgaatt tgaagcgtgt cgttcaagag aactacttaa tattatgttg attgaagaac
      901 cagaagctca tattcatcat catattcaaa aaactctgtt cgaaggatta aatcttcaaa
      961 aaaactatac tcagattctc atgaccacac attctgtaca tttagctgaa gtgtctgaaa
     1021 tatctcggat gaatgtatta aaatcgttta atggcaaatc tatcgttatg aatccagcaa
     1081 ataatctgaa ctcatttgct aaagaaaagt taaaaaagaa caatctaaat ctaataaacg
     1141 cagtagagag atatttagat gttaaaagaa atggattgct tttttctaaa ggtgttatct
     1201 tagttgaagg agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa ttatttggta
     1261 taaacttaga cgaacttgga ataggtttga ttaatgttgg tagtacttcg tttgaatata
     1321 tcgctagctt gtttgacgat gatagaatac agagaaagtg tgctattgta actgatttag
     1381 atgaacaggc aatcccatca gaacatcgat tgtataaaag cactgcacaa gagaaaggtc
     1441 aagcaagaaa agaaaaatta tcctcccttt ttaatgaaaa caattgggtt aattgttttt
     1501 atgctaatac aacatttgaa attgagtttt tagatgtgaa taaagaaaat attctaactt
     1561 atgtcagtcc aattatagat gacgcattca aagataaaaa aacaataact gcttataaag
     1621 aagaaataca aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa ctagccaatc
     1681 atgttggtaa ggggtggttt gcaattgagt taggtgaaaa aattgacttt ttaatcaaaa
     1741 ttcctaagta tattcttaat gctattgctt ttgcatgtca ggaaatagta gatctctcaa
     1801 tttataaaaa aattctactc catacaatcg acttgtacga ggaaactaca gaattgtcag
     1861 ctttatcagc tagtttaaaa acaagtgata cagctgattt gaatatagca ataatttctt
     1921 tattagagta ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag atagaaaatt
     1981 acacaaaaat actttatgct gaggtttcaa aatgacaaat atcttcgaaa aaatcgtaaa
     2041 tgatttaaat ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt atgtaaatgc
     2101 atgtcctggg agtgggaaaa caagggtact tacaaggaaa attgcttacc aagcaattaa
     2161 acacgatgga tcactaaaaa gaataattgc tatcacatac actaatagag ctgctgaaga
     2221 aattaaggaa cgcctaagtt tacttagtat agatgatgat attaatattt gggtggggac
     2281 aatacatcag ttttgtcttg aatttattat ttatcctttt aaaatgaatc tctcaagagt
     2341 atcaaaagga tttacaatta ttgatgatta tactcaaaga gcttacgtca gccaaattaa
     2401 taatatgctg aatttaaatc tcaaaacgta tgaactgaac aaaattgatt tgtcactttc
     2461 tcatgatttt aaaattaatg aagttcagta tactcaagtt tctgaaatgt atcacactat
     2521 gttggaaaaa aataaagaaa ttgattttga tatgatttta ctagtagcgt ataaaatttt
     2581 aactgtaaac agtaacgttg cacgtaatat tgctagtaat ataagggcga tttatgtgga
     2641 tgaatttcaa gatactagag aattacaata caatgtaata gctaaattac ttcaaaacaa
     2701 ccctcaaatt cagtcaatgt ttgttggaga tattgaccaa gcaatttatg gatcattaga
     2761 tggtatagct aaatcagttg aagaactaga aatgctaact agtcacactt ttcaatcaaa
     2821 gacgctacat ggctgttaca ggtctaatca gagattagta gacttctact ctaattttca
     2881 gagttgtcct tacgagattg aaagcagagg gaataataaa aacgaccgtg gttttataag
     2941 ttatgattgc aaagttacta aggaggattt acccaacata ataaaaaata taataaagga
     3001 aaagattgaa agcggcattc atgaaaaaga tatttgtgta cttgctcctc aacactatcc
     3061 tctgttttca ctgggtgagt atttaaagaa agaattaccg tattgcaatt ttgatgctat
     3121 aaatatatca ccaattaagg taaataatca tagtttattt ttcaagttag caattttgta
     3181 ctttactgaa tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg atattttaat
     3241 tatcttaatt gtcaaattaa gttagacaga tcatcaatac ttacgtaact caaaaatact
     3301 tccaaagg
//
LOCUS       DARBDN010000172         3221 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000172 DARBDN010000000
VERSION     DARBDN010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.177"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            301..585
                     /locus_tag="SCH06_002798"
     CDS             301..585
                     /locus_tag="SCH06_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079312.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="SCH06_002799"
     CDS             588..1004
                     /locus_tag="SCH06_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079313.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="SCH06_002800"
     CDS             complement(1141..1860)
                     /locus_tag="SCH06_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEG1079314.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2535..2630
                     /locus_tag="SCH06_002801"
     CDS             2535..2630
                     /locus_tag="SCH06_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEG1079315.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2932..3177)
                     /locus_tag="SCH06_002802"
     CDS             complement(2932..3177)
                     /locus_tag="SCH06_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079316.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1074 a          599 c          503 g         1045 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtactc
     2041 agataaaaag ttgttagtac ccttctgtat ccgttgggag agtaaggctc aactgccccc
     2101 taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat aaacgcgcgc gcgcgagcaa
     2161 aatttcccgc caaaaaatca cccacttttt aaaataaaca ggttcgcgca tgatattaaa
     2221 ctgccaatct agctccctat ggtcgctgta agaaggagtg atcgctacgc tctcacattt
     2281 tacttgcagc agtcgccttt aggctccttc gccaaaaata attcattagg gactcctttg
     2341 tggcgtcctg agagctcgtc taagccgttc taagacaaga ttcgataaaa actatgtcct
     2401 tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta acaaccccaa ggcaataaaa
     2461 aacttaggct tatttttgct tttttattgt ataattgatt gtcgcctatc cgacagtctt
     2521 gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat ttgctccctt cttgttgggc
     2581 ttttaagcgc tttgttcagt tactggttga ataaccgaaa caagaagtaa aacttaatta
     2641 aggcgactca gcccacaaaa aaagccccag agaatccgac ctctctgggg ctttcgtgtg
     2701 tttcgtgttc acttatttgc aatcaaatta taacagaaat aaatatttat ttcaaaaata
     2761 tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc aacatttaca aataaagtcg
     2821 ctctgagagc tcgtattttt cgatttaaga cgttttattt agtttttggt gtatttcatt
     2881 ggtccaagct aaaaaactct tagaagcgat tttagagcca tttaaaccca cttaattata
     2941 ttctccatga aattcgctcc atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt
     3001 cactagttgc attaattttt ccaacgatcg ttttctttcg ggtgtcatat ttttatattc
     3061 caacaatttt tcgtctgtta aatcgaactt gattgcttga attgcttgct ctaatttttc
     3121 taagttttga aaatattcgt aaggaaattt ttccattttt tctttctcca gtctcacaat
     3181 ttttctagaa ataaaatcac ttctttgccg tctatactct c
//
LOCUS       DARBDN010000173         3125 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000173 DARBDN010000000
VERSION     DARBDN010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.178"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            71..1372
                     /locus_tag="SCH06_002803"
     CDS             71..1372
                     /locus_tag="SCH06_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1079317.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            1375..2226
                     /locus_tag="SCH06_002804"
     CDS             1375..2226
                     /locus_tag="SCH06_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEG1079318.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            2239..3054
                     /locus_tag="SCH06_002805"
     CDS             2239..3054
                     /locus_tag="SCH06_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HEG1079319.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
BASE COUNT          869 a          586 c          601 g         1069 t
ORIGIN      
        1 attatcttgc tcttgttgcc attatcttaa aagcagtttg cggtttagca agtttagagg
       61 gggcattcag atgcagcaag ataaaacaag caatatcaac gaaaaaaaaa tcacgctttg
      121 ttcacttatt ccagggatgg ggcagtttgt aaatggccaa gcttttaaag gtatcgtttt
      181 tttcgccata ttcgtcctat tcattggtca gatgcttctg ggcggatttc atgcattggt
      241 aggattggtt actttgggaa gtataccaat ggaagatcat tcattattta ttttgattga
      301 aggcactttg caattcatca ttacaatcat tttcttgatt ttttacggtt tgaatctttt
      361 agacgcttat cgagtagcga agatgcgtca agagggcaaa aaaatcaatc ggacgatgaa
      421 ggaagtcata cataatatag gtgatgaagg ttttccttat ctattgacac ttcccgctta
      481 tcttctcatg atttttacga tcattttccc agtcctagtt acattgttca ctgcatttac
      541 taattatgac ttcaatcata ttccaccagc cagtttaatt gattgggtag gggctaaaaa
      601 cttttttagt atcttctttt taagctcata tcgtaatact ttttttgcag tcttttcgtg
      661 gaccgtgatt tggactttat gtgcaacaac tttgcaaatc acccttggta ttctcacagc
      721 ggttgttgct caccagaaat ttattaaatt caaacgtatt ttcggtatca ttttcttatt
      781 accatgggcg gtcccagctt ttattactat catgagtttt tcgaatatat tcaacgatag
      841 cgtaggtgcc atcaatactc aagtgattcc tttcataaac cagcttcctt ttgtagatat
      901 cagtgcaatc tcttggaaaa cggacccgaa ctggacgaaa gtagcaatta tcttagtgca
      961 gggctggtta ggatttccct atatctatgt gatggttaca ggaatcttac aatcgatttc
     1021 agaagactta tatgaagcag caaaaatcga cggagcaaat gcatggcagc gcttttcaaa
     1081 catcacgctt cctgctgtct tcctagtggc agcgccaaca tttattacac agtatacggg
     1141 gaatttcaat aatttctcca tgatctatct gtttaacaat ggcggtcccg gaagcgtagg
     1201 cggaggagct ggttctactg atattcttat ttcctggatc tataaactta cgactggaac
     1261 ttctccgcag tattctatgg cttcagcaat cacgttgatt atctccgtca tcgttatctg
     1321 tgtgtcattg ctggtattta aaaagacaaa tgcgttcaat atgggggatt aacaatgaaa
     1381 aaatttcatt cgagtgctcg attccaaaaa cgactttctc acttttttac ttactttttt
     1441 cttttaatac tgtcagtcat tatcatctat ccgcttttga tcacagcaag tactgccttc
     1501 aagtcaggaa atattgcagc ttttagttta gatctttcaa gtgactggac tttaggaaac
     1561 tttactcggc tattcagtga aacactttac gggacttggt ataaaaatac attgatcatt
     1621 tctgtcctaa caatgatcgt acaagtgact gtagtaactt tggcgggcta tacttatagt
     1681 cgctatcgtt ttatcggccg caaatcaagt ttgatgttct ttttagtgat tcagatggta
     1741 ccgactatgg cagcattgac tgccttttat gtcatggctt tcttattaga agcgctcgat
     1801 aagtactggt tcttgacaat gatctatata ggcggtggaa ttccaatgaa tacttggctg
     1861 atgaaaggat actttgacac tgtaccaata gatttagatg aatctgctaa acttgatggg
     1921 gcagggcatt tcaggatttt tttccagatt gtattaccgc ttgtcaaacc gatgctcgcc
     1981 gttcaagcat tatgggcttt tatgggacct tttggggatt tcatgttagc taagttcctg
     2041 cttcgaacac ctgaaaatca gactgttgct gtcggcttac aaacatttat ttctgatgtg
     2101 acaaaccaaa gagtctctct ttttgctgct ggggcaattt tgattgcact accgatttgt
     2161 ctattattct tctttttaca aaagaacttt gttaccggcc tgacatctgg cggaacaaaa
     2221 ggataggagc agagtatcat gcaaacattt ccgttaaact atttttccgc attacgtacg
     2281 ccaactcaag tgtttgcggg acgcaaacta ttatcatggc ctaaattttt cttgatattt
     2341 gtatttttag tttccttgat ggtcatgcct gtgactcttt tttatgccaa tcagatccaa
     2401 gcgattccat tagaacaatt tctatccgtt cattcgctga tcgatgaaca aggaacccaa
     2461 aaattttctg aacttgaatt atctgaaact gggttacaag catcgcaaca aacgatagct
     2521 gtgacccctg aaattttggt aggtgtgtct ttatctgaga aacaacaatc cgatcatgga
     2581 acttttattg attttgagaa ggaacaatgg gtgatccaac aaaaggataa atctggtata
     2641 cgccgctata cgatgaatta tagcccatct ttccaaccag attctgtacg tacgcccgaa
     2701 gatttccaac gatttttaga aagagaattt tatgccagta atcgtccaac aatcatttta
     2761 tcttatagtt taagtcttgg tcttgtccta tttgtcatga cgagtctcat tttattcggg
     2821 gcttcctttt tcttgtggat gacaagaaaa agccaacttt catccattca tacattcaaa
     2881 gagagtgcaa atttgatgct gaatgttatg ggaataggtt ccatggcagc agcagttgta
     2941 gggtttatcc actttgactt tatcttgatg ctaagtgtcc aaacaacgat aactgtcttg
     3001 ctgcttttat gggtttttgt caaaacaaga ttcaaagata agcgtgtcga atgacaagtt
     3061 taagcgattt atgcgacaat gaatgtgaaa aaaatgaaaa ataaagtagt ttttgaaaaa
     3121 tttct
//
LOCUS       DARBDN010000174         3095 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000174 DARBDN010000000
VERSION     DARBDN010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.179"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(83..1018)
                     /gene="murB"
                     /locus_tag="SCH06_002806"
     CDS             complement(83..1018)
                     /gene="murB"
                     /locus_tag="SCH06_002806"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEG1079320.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1091..2011)
                     /locus_tag="SCH06_002807"
     CDS             complement(1091..2011)
                     /locus_tag="SCH06_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1079321.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQEADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2124..2876
                     /gene="xth"
                     /locus_tag="SCH06_002808"
     CDS             2124..2876
                     /gene="xth"
                     /locus_tag="SCH06_002808"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEG1079322.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          872 a          631 c          538 g         1054 t
ORIGIN      
        1 gcgccatttg cgtaaacaac cacaaaaaag agcaggacgg ccaccgtcct gctcttttac
       61 ttattttaag ttccattact tattaattgg ctaaacttct gcttgtttct gatattgctt
      121 gtttttctcc aatgatccgc acttctgttt ctaaagacac atcaaatttt tctttgatta
      181 cttcttggat gtgcgcaatc aattcaatat aatctgtcgc tgtcgcatga tcgatattga
      241 cgatgaatcc agcatgtttt tcagagactt gtgcaccgcc ccatttcagg ccttgcaatc
      301 ctgcttgttg gatcagctga cctgtatagt gtcctactgg gcgcttaaag acacttccgc
      361 atgaagggta ttctaatggc tgttttgatt gacgcaattc ggtcaactca tccattcttg
      421 ctttgattgc ttcataatcc cctgtttgca aactgaatcg agcttccaat acgatagcac
      481 gtaattcttg gactttactg tgacgataag aaaataccat ttcgtctttt gtcaaagttt
      541 tcaatgttcc atcttcaagc aaaagatcca cttcagcaaa aacatctttg atctctccgc
      601 catacgcacc tgcattcata taaaccgctc caccgacact tcccgggatg ccgcaagcaa
      661 attcaaatcc agtcaatgat tctgccaaag ctgcataagt cgtatcaatc agtgaggcac
      721 ctgcttccgc aatgaccatc gttcctttga catgaatctg tttcatttca gtcagcatga
      781 tgactacacc gcgaatcccg ccatcttgaa cgatcagatt gcttgcattt cctaatacca
      841 tccaaggtat atcatggatt cggcaataat cgatgatttg ctttacttct tcttgttttt
      901 tcgggaatgc aaggacatca gctggtccac ctgttttcgt aaacgtatag ttcatcaatg
      961 gttcatcaaa caatatagta atcgtggcta agctttcaac tatttcttct ttattcactg
     1021 aggattttcc tttcttttct caaacgtcct cattattcta tcacgcttaa tacaatcttg
     1081 ccagtcttgt tcaaagttga tgacggtagt gatctttaag cacttcctca cataattcat
     1141 gacttcttac aacttctttt tgtttaagca attctgtttc cgatttacct aaacggatct
     1201 gagaaaagaa ggcctctacc attggctcaa acccgcgttt gactagcgtg tttgtccagt
     1261 cgccaaattc tttcactttt tttccatcag cctcttgaat gacaagctgg gtcagatcgt
     1321 ttacttcata agtaccattt ttacttgtta cttgatattt ttctatatta gcgccacttg
     1381 ctaaatccat cgttaaaata gccgtttgat tttgtgtttc taattgtaaa atggcatatt
     1441 ccaaaaattc ctttgtttct cttatctggt attttgttct caaaatgggt tcatctaata
     1501 aatacacagc tgtatcaata agatgtaaaa acaaatcata aaggacgaac tctgtcgttt
     1561 cttttgccgc tattcgattt ttttgcaggt ggatcaaccg cttatctggg atacgtttca
     1621 attcttctac cataggagca aagcgccggt tgaaaccgat catcaaaatt atttggttct
     1681 tatcagctaa ttcttgcaat tcacgaactt catttagatg gacactcagt ggtttgtcaa
     1741 tataaacatg gataccattt tctagacatt ttttggctaa ttcataatgt acttttgttg
     1801 ctgcgtggat catacatgct tcgatttttt cttctaaaag ctcatcgatc gtttcatata
     1861 gatgttggaa cccgtactct ttttgaattc tttcttttgt ttctttattt cttgttgcaa
     1921 aataaaaatc aagtgttcct tgttttttcg cataagttgg taaatatgct ttttctgcga
     1981 tattccctac accgattaca ccaatcttca tctactttcc tcctggatca tttagttact
     2041 ttcatcttac accatttttt actaaaatga ggtacaatag tatcgcaaag gtaaggaaat
     2101 taattcgaag gagtgtgctt ttattgaaat ttatctcttg gaacgtaaac gggcttcgtg
     2161 ccatcgtaaa taaaaatttt ttagaagttt ttcatgagtt agacgccgat tttttctgtc
     2221 tgcaggaaac gaaactccaa gcaggacaaa ttgatttaga tcttccaggt tattatcaat
     2281 attggaatta cgcggaacga aaaggctatt ccggcacagc gatttttgct aaaaaaccag
     2341 cattgaatgc cacttacgga atgggtatcg atatccatga tacagaaggc cgtctgatta
     2401 ctttggaata ttccgatttc tttcttgtaa cctgttacac gccaaattct caaagcgaat
     2461 taaaacgttt agattaccga ttagaatggg aagaagcctt ttataattat ttggaaaatc
     2521 taaaaaaaca aaaaccagtc atcgtgtgtg gggatctaaa tgtcgctcat caaaagattg
     2581 atttgaaaaa ctggaaaacg aatcaaaaaa atgctggatt cactccagaa gaaagagcgg
     2641 ctctttctcg actgttggat aacgggttta tcgatacatt ccgttatttt tatccaaccc
     2701 aggaaggtgt ctactcttgg tggaactacc gattcaattc aaggaaaaac aatgctggtt
     2761 ggcggatcga ttactttttg acgagcaaag atttagagcc aggactagct gatgcaaaga
     2821 tccatacgga cattatgggc agtgatcatt gtccagtaga attagatttg aaataaagag
     2881 gttgtgaaaa agtcgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
     2941 cattttgcat aaatttggca taataccgag aaactggctt ttgaacactg tttatcgaga
     3001 gattgtgaaa aagctgtcct gcatcaagta ataagaacag ccaaacaaaa atagttcctc
     3061 atatttttcg tttggttggg cttattaccg cagat
//
LOCUS       DARBDN010000175         3013 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000175 DARBDN010000000
VERSION     DARBDN010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.180"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            177..359
                     /locus_tag="SCH06_002809"
     CDS             177..359
                     /locus_tag="SCH06_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEG1079323.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            462..746
                     /locus_tag="SCH06_002810"
     CDS             462..746
                     /locus_tag="SCH06_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079324.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            762..998
                     /locus_tag="SCH06_002811"
     CDS             762..998
                     /locus_tag="SCH06_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079325.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1020..1274
                     /locus_tag="SCH06_002812"
     CDS             1020..1274
                     /locus_tag="SCH06_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079326.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1356..1541
                     /locus_tag="SCH06_002813"
     CDS             1356..1541
                     /locus_tag="SCH06_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEG1079327.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1608..2003
                     /locus_tag="SCH06_002814"
     CDS             1608..2003
                     /locus_tag="SCH06_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEG1079328.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1993..2370
                     /locus_tag="SCH06_002815"
     CDS             1993..2370
                     /locus_tag="SCH06_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079329.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2392..2766
                     /locus_tag="SCH06_002816"
     CDS             2392..2766
                     /locus_tag="SCH06_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079330.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1058 a          507 c          523 g          925 t
ORIGIN      
        1 tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacac ttttaaattc
       61 ttttctgggc tttgttttta gggtagggct aaaaaaaaca tcaccatctg atccaaaaca
      121 gctcagaaac gcattttaac gtatctgata ccaatattac agaaggagtg tatcgtatga
      181 ttaacctatt tcttttagtg acagctagta cattattctt tactggaata tcactgataa
      241 tttcctattt gatctataag aaagccgaaa atcacacaag caaagcaatc ggactagccg
      301 tttcatcctt tttaactttg ctgactttat ttgttacttt atcgttttct tttgtttaga
      361 acagctgatc cattagcacc tttttctctt tacattatac acactgttgt gtataatgta
      421 tttgtaaaca agctaattaa cttttaggaa ggagtgacaa gatgctaaca gctactttac
      481 agcaacctac tcacgttgct attgcagaaa gttatacaat taatgcaggg atcgttaaac
      541 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg gcaagcgtat aacagacagc
      601 taaagaaagc tattctaaag cacaaagatt ccttcatcgg gaacttggaa agtgtagatg
      661 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
      721 ctctatttgc ttttggaatt aattgatagg gagtgtgaac tttggaaggt aagacttttg
      781 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
      841 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttgga
      901 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
      961 ccgagtggga tgcaattgga aatatccatt tttcttaata taagaaagga gaacacaata
     1021 tgaattatac cgatgaagaa caaatcgctt tggaatacgt tttcacaaat gaagaagggg
     1081 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaaggct ttggcttatg
     1141 aaccatacga atcaaccgta actgtcattg aattcttaga tacctatact tctaatgata
     1201 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     1261 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     1321 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     1381 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     1441 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     1501 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     1561 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     1621 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     1681 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     1741 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     1801 tggaagaatt aactttgaaa gccaaccaag tggtagtaat catccaacta aacattaaac
     1861 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     1921 tagttctttt agggaaggag aaaaacataa acttctctca actacttcaa aaagcactag
     1981 aagaagagtt gcttgaaaag taaaaaggag accgaaccta tgaaagctac acacttaaac
     2041 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     2101 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     2161 tttattgaac aggcaacccc taactcaata cctgaattct gctatacgca cactgaaaaa
     2221 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     2281 ttaaacctcg ttaagaaggc aaaattgtta tttgaatttc aaaccgacta ccacaatgag
     2341 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     2401 acacaaacag aaaccgttaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     2461 tttgagatgg gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     2521 cttttttggg aatcaacact aacattctca gttctttttt ataagtcaga tttttataat
     2581 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     2641 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     2701 aaaagggtat ccttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     2761 ttctgagagc ttttgacatt ttcttgtata attttatcct aacacattac aaagcaccta
     2821 attcgagctt atatcaagca aatttgctat ttattactca atacatatct aaaaattact
     2881 tgatggaaaa ttagatacat ggtaagcatg aaaagaaaat caatttgagc agatgcagta
     2941 caatacatag caatttaaaa gctctcagaa ggcttctgag agcttttaat atattctttg
     3001 ataatttgtc ttt
//
LOCUS       DARBDN010000176         2739 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000176 DARBDN010000000
VERSION     DARBDN010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.181"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="SCH06_002817"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="SCH06_002817"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEG1079331.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1072 a          425 c          558 g          684 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatata
//
LOCUS       DARBDN010000177         2654 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000177 DARBDN010000000
VERSION     DARBDN010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.182"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(909..1427)
                     /locus_tag="SCH06_002818"
     CDS             complement(909..1427)
                     /locus_tag="SCH06_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEG1079332.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            2545..>2654
                     /locus_tag="SCH06_002819"
     CDS             2545..>2654
                     /locus_tag="SCH06_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079333.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT          881 a          478 c          392 g          903 t
ORIGIN      
        1 agttagatta ataaaaatac taaagttatt tgttctttta ttaaatacac ctacaactta
       61 taaattgatg gtatttagat aacacgaaag aataaaaata acagctgata gtaaagtttg
      121 ttgacgattg ctactcaatc gaaagtgagt tagtgcgtat gaacttgctt ctgaaaactt
      181 atgaaatgaa agacctttta catcttgcag aaatcggtac tgggattaaa ctaagcaata
      241 aaaactaatg ttcccctcat tctttgaact tctactattt gatttattta ttctgataaa
      301 tgacgatttc accttcagga tcttcaaatc ccgtatagaa tttatttaag atctcttcag
      361 tatcagtaat aggataggcg ataggccaca taccctttga tggttagaat aaactgctca
      421 aaatctgtat cgtatgttgg ctttagcata ttaacaaagg ctatctccaa attataaacc
      481 ataagcgttg aatcgttctt aacaatttca attcttccta acccaaagtc agaagatata
      541 attaccggac ttgccttacc cttcatgtgg gttgttgaga ttccatattt aaagggaatt
      601 gtcggtacta tcggcggtct gaaaaacatc ccaaaaataa aaaaatcttt cccctgctag
      661 tctcctaagt ccctttgtag cggatatggc accataatct cattttatcg aagtgagtca
      721 tggtttatct gttggccaac caaaattgat acaatctaac gatgcaccct ctacggcatt
      781 ctaggggagt gcacttgcat tcacccaata aaaaccggca gttagcaaag aacttatgta
      841 gtcgtatgtt cttactgtta acatacaaga ggtctccttt ccacaattgc ttagcagtaa
      901 acgggaattt acaaagctaa tctcttccat tttcttatct ttgttctaaa agtcccaaat
      961 ggagcaactg tatttacatg aataaattta tatacttccc atacagccgt tttggttgcc
     1021 tcgtctgccc attttctttt gtgtgcagtg aatagatctt catcactcat tgaatcaatc
     1081 atcatgttaa tatcatcaat attacgattg agaatttcct ctaattcttt caatggtaga
     1141 tgtgcatagg tatttgtaaa ccacttatat aactctccta actgattcca tttaaattga
     1201 tcagaaggcg ttttaacaga taatccattt ctttcatcat tttcccattt tagaattaaa
     1261 ttcgtccaac caacttgata tgctaaattt tcagcaggtg ttctatccac ttcctcaact
     1321 cttttatcct tcaattcttc aggaatagtt tcaaattcta aaatatattt agtataagtc
     1381 ctatttattt ctttttttaa ttcttcttta tttttatatg ttctcattat attacctcca
     1441 taaattccta attgtctcct ttaattcatc tataatttca tccacgatat tttaatccgt
     1501 tctacaatgc atatctgata tgcattgact gtctaactca tatgtgaatg atttataaaa
     1561 tatcccaacg tctcatctaa agaaatgttg atcgtcagca aggagctaaa aaatacgaat
     1621 atatttcttt tgtagtaaaa tcggactggt ttgcatatca ttttcttcgt aaatatcaaa
     1681 atcatgttaa ctactatcaa ttactaataa aaactaccac tttaagcgtt aagaactgtt
     1741 aagtttagtt aagtgaggat agttcacaaa atccattgtt aaacttcacg aaagtggtaa
     1801 aactcaaaat gctttatata ggattacagc atcgctcttt cttcgattgc gcgttgggta
     1861 aaaaatatta tgaagtaaaa attgacgatg acacgttcct tacggctcat cagatgaaac
     1921 agctacaaaa acgaaatgat caactcgaag aaaatttaat tctaaaaaag cgattgccat
     1981 attcacgcct cgctcgacga actattaaag gtcaagattt acctgaagat catccttttt
     2041 aggaaattga agctttttat gttgcacaat gcatttataa tactacaatg atgttttcac
     2101 cagatattct tctagggtgc ggtgtaatga aacagataca cttgcaaaag aaaattcacc
     2161 gcgaatttac taaaattatg aataattatg ttaatcttcc gaaatttttt tccaaaatta
     2221 agggatcaag ctggtgttat agattgttta aggttggcaa aaaaataact tctttttaaa
     2281 caattataga aaaccgatac tctgttaagt tggttgacac ggtgtcgatt tttatgactt
     2341 tcttattctg aaacttcact aacggacagt acctaaaaag tctatagtat ggacgtttac
     2401 gagtactatt ttatcaaaaa tgctgctcat ttcaacttat atgttttagt gaactacccc
     2461 cacttagctt ggataggcta caattaacta gacagaaaaa ttaaggtgtg tagactagaa
     2521 gaaaacatac caggaggaat ttttatgtct aagagaacac gaagaacttt ttcacaagaa
     2581 ttcaagcaac aaatcgtcaa tctttactta gctggaaagc cacgtgtaga aatcattcga
     2641 gaatatgaac taac
//
LOCUS       DARBDN010000178         2417 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000178 DARBDN010000000
VERSION     DARBDN010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.183"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            113..2266
                     /locus_tag="SCH06_002820"
     CDS             113..2266
                     /locus_tag="SCH06_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEG1079334.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          824 a          425 c          535 g          633 t
ORIGIN      
        1 attttatctt gaaattaggt aaagaatttc ttgctccgcc cattttttct tttttattaa
       61 gaagtttttg ggtacaatga agcatgaatg taaataggcg gaaggatagg aaatgatgaa
      121 agattttatg aaaaaaatat taaatacttc ttggttagaa aaaataagaa aaggtgcaca
      181 agaacctaag aacaaaacgt ttcgccggtc ccatgttcct tttcgcttaa attttctttt
      241 tttcattata tttacgttat ttgttgcgtt gattgctaga ttgggttatt tgcagatcgt
      301 gaacggcgaa gagatggagg cgcgagtgaa gtctacttct acgattacgg tccaagaaag
      361 tactcctcgc ggaatgatct acgactccac aggaaaagct ttagttacga ataaagcgaa
      421 tcaggccatc acatatacga gaggaacaca agttacggct aaagatttgc ttgaaatcgc
      481 aacgaagctg aactcgctga tcgatgttcc ggtagatgaa aatctgacag atagagataa
      541 aaaagatttt tggctggctg atcccaaaca tttgaaagaa gccacaaaaa gactttcggc
      601 aaaagaaaag caattaggga acagcgaaca atatagtgcg atggtcaata aagtcacagc
      661 tgatgagatt aatttaaacg aggagcaatt aaaaattgct accatcttta aacggatgaa
      721 tagtgcatat gaattaaaca ctgtctatat caaaaactct ggtgttactg atcaagagtt
      781 agctgttgtg gcagaacgcg cttctgaact tccaggagtt tcgactggca cagactggac
      841 acgagaatat aatgcagcaa gttcactgaa aagtattctt ggcagtgtga cgactgaaaa
      901 gcaaggactt ccagcagatg aagcagagaa atacctagca aaaggttatt ctcggaatga
      961 ccgtgtagga caaagttatt tggaaaaaca atatgaagat gtcctgcaag gaaccaaaac
     1021 ccaatatgaa gtttcccttg ataatgaagg aaatgtttcg aatcaaaaag aaatcttctc
     1081 tggggaaaaa ggttctaatt taatgttatc tatgaatgca gaattccaat caaaagtaga
     1141 agaaattttg aaaaggaatt atcaaacatt gatcaacaac ggcaaagcac agtattcgcc
     1201 tggtgcttat gcagtggcta tgaatcctca gacaggagaa gtgctagcaa tgactggttt
     1261 cagtcatgaa caaggttcca aagaaatcac cgagaatgct ttaggcacga ttactagcgc
     1321 ctttgatcca gggtctgtag tcaaggctgg tactttgaca gcaggctggg caagtaacgc
     1381 gatcagcgga aatcaagttt tgattgatga gccgattcgt ctgcaaggtg cttcagaaaa
     1441 aagctctgtc tttaatcgaa gcggacaagt tgctcttgat gcagtcaaag catcggaatt
     1501 gtcttctaat acgtatatga tcaaagtggc gttaaagatg ttaggactag actatacacc
     1561 tggaatggga ctacctagtt tagatgaaga agctaaagct tatcagcaat tgagagactc
     1621 tttcaaagag tttggtcttg gtacaacgac tgggatcgat ttgccgaatg aatctcctgg
     1681 gatctcacgt tctgttgatt atatgaagaa gttcaatgcg gataatggca aagaatggta
     1741 tgctccaggt aactttaccg atttggcatt tggacagttt gacacatata caccaatcca
     1801 attagctcaa tatgcttcaa cagtcgctaa tggcgggaaa cgagtacagc cgcacctagt
     1861 caaagcgatc tatggcaatg acgaaaatgg aaacttgggt gaagtgaaga aagaaattgg
     1921 cacaacagta gaaaatacgg tcaatatttc tgcagaaaat atggcgatcc tccgtgaagg
     1981 attccaccaa gttgtccatg gtaccgatcc ttacacaaca gccaaaccat tagccagtgc
     2041 gaaaatggac ctttccgcaa aaacagggac tgcagaaacg gttgcggaag gtcatccaga
     2101 tattgcgaca gtcaatagta atatcgtggc atacggacca acagacaatc cggaaattgc
     2161 catcagtgtt gtcttgccga acttattaga cgaacaagac cacataaact tgacgattgc
     2221 taaagaaata atggacgcgt attatgatat gttcatggca aaataaaaaa gaggtcgtga
     2281 aaaagccgct tagtttcgag tatgaagaaa aattttgtga aaatagcttc tcacattttt
     2341 gcttaaattt gacttcatac cgagaaactg gcttttgaac accgtttact cggcaaaaaa
     2401 ggttgtgaca aaaattg
//
LOCUS       DARBDN010000179         2407 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000179 DARBDN010000000
VERSION     DARBDN010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.184"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            5..1150
                     /locus_tag="SCH06_002821"
     CDS             5..1150
                     /locus_tag="SCH06_002821"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEG1079335.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="SCH06_002822"
     CDS             1321..1779
                     /locus_tag="SCH06_002822"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEG1079336.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..>2407
                     /locus_tag="SCH06_002823"
     CDS             1938..>2407
                     /locus_tag="SCH06_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEG1079337.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          802 a          452 c          455 g          698 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgttagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttcttta
//
LOCUS       DARBDN010000180         2400 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000180 DARBDN010000000
VERSION     DARBDN010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.185"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            207..2069
                     /locus_tag="SCH06_002824"
     CDS             207..2069
                     /locus_tag="SCH06_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1079338.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="SCH06_002825"
     CDS             2069..>2400
                     /locus_tag="SCH06_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEG1079339.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DARBDN010000181         2351 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000181 DARBDN010000000
VERSION     DARBDN010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.186"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..333
                     /locus_tag="SCH06_002826"
     CDS             <1..333
                     /locus_tag="SCH06_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HEG1079340.1"
                     /translation="YLTILKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKN
                     IINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIK
                     WIQKQIAY"
     gene            306..983
                     /locus_tag="SCH06_002827"
     CDS             306..983
                     /locus_tag="SCH06_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEG1079341.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            973..2115
                     /locus_tag="SCH06_002828"
     CDS             973..2115
                     /locus_tag="SCH06_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEG1079342.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2128..>2351
                     /locus_tag="SCH06_002829"
     CDS             2128..>2351
                     /locus_tag="SCH06_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1079343.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITH"
BASE COUNT          867 a          310 c          471 g          703 t
ORIGIN      
        1 tacctgacta tattaaaaga gtgcaaattt atgatcggaa attcttcttc tgggataatt
       61 gaagctgcat cattcaaaat accagtaata aatttaggaa ccagacaaaa tggacgagaa
      121 caatctaaaa atattataaa tgcaaatcta aatgaaaatg aaattgaaac tgctttgaat
      181 aaaatacaag atcctcagtt tataaaaagc ttgaaaaatg ttaagaacat ctacggtgac
      241 ggcaacagtt ctagaagaat aacaaaaaca ttgaatcaaa tattgaatga tggggaagat
      301 attaagtgga ttcaaaaaca aatagcttat taaaatatac tagtgatcca tacattatta
      361 ttggggctgg cggacacgca aaagtcatta ttgaaacctt aagattagaa aataagttaa
      421 tatatggatt ttttgatgat aagcaaaata aaatgcaaga tctgaaatat cttgggaaaa
      481 taaacgaatt gaatagctgg gcggatagca aaaaaaaaat ctataaattt attgtagcta
      541 ttggtgactg tgtagtaaga aaaaagatta taaaaaaatt gaatatgcca agtgagcaat
      601 atggaatagc tgttcatcca agtgctatag tggcaaaaga aatttcaatt ggttatggaa
      661 ctgttatttt tgcgaatgct gtaattaacc cagatgctgt aattggagag catgctataa
      721 taaacacagg tagcattgtt gagcatgatt gtagaattaa taactatgtt catttatctc
      781 caggtgtatg cttagcgggt ggagtacatg taggtgtagg aactcaaata ggaattggtt
      841 ctcaatgtat ccagatgaag aaaattggat cttggtgtat gataggcgca gggagcacta
      901 ttgttaagga tattccctca cattccttag cttatggcaa tccagctaaa attaagaaag
      961 aaggaattaa ttttgaattc tagaatttta ttatcaagtc ctcatatggg aggaacagaa
     1021 gaaaaatatg ttgctaaggc ttttaaagat aattggatag cgccattagg tgaaaatgtg
     1081 gataaatttg aagaaagtat tacaaaatat actggttcta agggcggagc ttctgcgtta
     1141 agttcaggta cagctgccat acatcttgcc ttaagactgc ttaatgttgg aaaaaacgat
     1201 attgtctttg ctccttcatt tacttttata gctacagtaa atcctatttt atatcaaggg
     1261 gctgtaccag tgttcattga ctcagaacct aatacatgga atatgagccc tgttgcacta
     1321 gagagcgcat tagaagaagc tgaaagaaac aaccaattac ctaaggcaat catcgtagtg
     1381 aatttatatg gtcaaatggc tgattatgaa cgaattttag ctattgcaaa ccaatttaat
     1441 gttccagtga tagaagatgc agcggaatcg ttaggttcta cttataaggg aatttcgtca
     1501 ggcttatttg ggacaattgg gatctattca tttaacggta ataagatcat cacaacctca
     1561 ggtggaggag ctctagtgtc tagtgataaa aaatatgttg agcattcaag atttttagca
     1621 acacaagcaa gagatcaagc accgtattat caacatagcg aaataggtta taattaccgt
     1681 ctaagcaata tttctgccgg tatcggacgt ggacaaatgg aagtattgaa tgatagagta
     1741 gctaaacgaa gagaaatttt caatcgatat aaggaagctt tttctggaat tgatagaatt
     1801 gaaatgatgc cagaagtgga tggcatggtg ccaaatcgtt ggttgtctac tttaacgatc
     1861 aatgattata attctattga tcaagtagtt aacgtaataa ataaactaaa tgaaaaaaac
     1921 attgaaacaa gagctttgtg gaaaccacta catttgcaac cagtatttca aggggtaaaa
     1981 atgtattacc atgataataa tcttagtgtg tcagaaaagt tatttaatag cggcttatgc
     2041 ttaccttctg gaagtaatat gacagatagt gaacaagaat ttgttattga tgagtttaaa
     2101 aaaatattca agtaggtgtg atattttatg aacataggaa ttattggttt aggttccatg
     2161 gggaaaagaa gacttagact cattcaagaa cactttaatg atattttact atgtggtgtt
     2221 gatactaatg aggcgagacg aaaggaagtt gaaaaggaat ttggaatacc aacttataat
     2281 agtctaacag aggcaaaaaa tttgtttgaa ataaattcag tttttgtttg tacatcccct
     2341 ataacccatg a
//
LOCUS       DARBDN010000182         2288 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000182 DARBDN010000000
VERSION     DARBDN010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.187"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            202..1077
                     /locus_tag="SCH06_002830"
     CDS             202..1077
                     /locus_tag="SCH06_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079344.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1222..1374)
                     /locus_tag="SCH06_002831"
                     /pseudo
     CDS             complement(1222..1374)
                     /locus_tag="SCH06_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1642..>2288)
                     /locus_tag="SCH06_002832"
     CDS             complement(1642..>2288)
                     /locus_tag="SCH06_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEG1079345.1"
                     /translation="VTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFL
                     IQNMQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFA
                     KLSVTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQI
                     PWTTPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
BASE COUNT          817 a          409 c          359 g          703 t
ORIGIN      
        1 ataaataaaa aacaaaaaaa gttccatctt taaaacacgc tattctttta ctttttctca
       61 cattctctaa gaaaagaaaa ggagaatgaa tttttgacaa ttcgagcaaa agtgattatc
      121 aaatatgtaa aatcagctac ttttttctta aacgtttctt tatactaaat ataaataagt
      181 gtttcatgaa aggagaacta gatgaataat tggcttgagt attttcctga aaacgttttg
      241 gaacgcggtt acagctatca tctgcacggt tttgtccgtc atttgaacta tacaagcaag
      301 tacttgtccg caacagtttc tggcacggaa gattataagg tagtgatcac ttgggatgaa
      361 aagaccaaca tgacttgtga ttgtctatat gccatagaag gaaaaaaatg caaacacatg
      421 gctgctgtct tattcgctta cgaagaacgt ccaataaaaa aatccaacta ctcactttcc
      481 gaactctcgt cccttgtttc ctccgctagt tcctctcttg tacgggagct tttaacagag
      541 attcttatag aacatccgca atttatcgaa cgcttcaaag ttaagatgcc atttcatgca
      601 ataaattatt cagataaatt aacaactatc atccataaat acgatcatat tatcaagaaa
      661 aacaaaaaca ggaaaacagc gaagttcatc atggagatgc gaaagttcat ccaagaagca
      721 gttgaatcgc tcattcagca aaatgcctat cttcccgcat tcgaattgat caatgaagtg
      781 attgctactc tcgaaacatt ctattgggag cctgaggatg aacgaaccct tcttctgata
      841 gaggactgtt attatttatg gaaagaatta ttagcagaag cacctcatgc agaaaaaagg
      901 caaatgttct cttggttcgt ctgccaagtc gatcatactg acgcctctta ttcaaaacgc
      961 tactccataa aaatcctgaa agaagacttt cgggaaaaag aattttctaa ccaaaagaaa
     1021 aaaatagata aaaaaactaa agaaacggta aagaaagacg atttcaatga aaaatagcaa
     1081 gtaaacgata acaaccatcc taaatccaca agaaatacag cagaccttgc tttaaaaaca
     1141 cgaatcatgc aaaggatgaa gtaaagaaga cttaacgcgt acccaatatt agtcatttga
     1201 ctattaggta cgcgttttgt tttataagtc atgacaaatt tccttcgttg ctgggtagat
     1261 tttccggcat tgttgataga ttttatgata cttttctaca ttttgtaaga gaggttccac
     1321 tgcatctgta tattggataa aattctgaca acaactttca ggtgtgtcga accactctaa
     1381 tctttaaaga taaatattaa aataacgatt aataatatta acagtcttta tttttcacca
     1441 ccaaaaacct atctttgcat atactaaata gacgtatata cacagatagg tttgtcttgt
     1501 gaaaaataat gattatcctt accaaaaaat gtttgttttt ctacatgttc gtacttatca
     1561 aaaaatatga tccttattga aattactggc tatttatatt ccaacgactt cttgtgttaa
     1621 tttttgttat ctcatagtaa attatgtttc attttcactt aatttagttg tcacgtgttc
     1681 gtcaattcgt aaaaacggta aatatataaa cacacttgcg gctataatta atatttgtaa
     1741 aacagctgct cgccagtctc cggctgttgc taaaaatccc gatataactg gtggcgtagt
     1801 ccaaggaatt tgcactacta catgattaat taatcccaca gcagttgcaa aatatgctac
     1861 tgtcaaagaa aaaatcggtg caagcacaaa gggaataatc agactgatat taaatacaat
     1921 aggcaatcca aaaataatag gttcgcttat attgaatata gcgggagtta ccgataattt
     1981 agcaaagtcc ttataatctt ttctacgact gaagataaat attgcaatca ataaagcaat
     2041 cgtatttccc gatccaccca ttaccgcaaa ggtatcttta aaggccatat tgataatatg
     2101 tggaatttgc tctttgtttg cataagctgc catattttct tgcatattct gaatcaaaaa
     2161 cggatctaac aatgaacctg atattactgc ttgatggata ccaaatccaa aaaatagatt
     2221 agcaatagat gtaattaaca aaaatcctgg taaaccagtt gtaattttac ttaatggctc
     2281 tgtaacta
//
LOCUS       DARBDN010000183         2287 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000183 DARBDN010000000
VERSION     DARBDN010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.188"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..934
                     /locus_tag="SCH06_002833"
     CDS             <1..934
                     /locus_tag="SCH06_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEG1079346.1"
                     /translation="ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVD
                     VSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASE
                     GIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNK
                     PQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIV
                     TATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPK
                     TGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1068..>2287
                     /locus_tag="SCH06_002834"
     CDS             1068..>2287
                     /locus_tag="SCH06_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEG1079347.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSL"
BASE COUNT          905 a          289 c          438 g          655 t
ORIGIN      
        1 tgcagataaa tacaatcctg aaggacaaaa agtgactaca gacttaaata aagagccaga
       61 tgcatctgag ggaattaaga acaaagaaga tttaccaaaa ggaactactt atgcttggaa
      121 agagaaagta gatgttagca cagctggaaa taaaaaaggt actattgtag tgacatatcc
      181 agatggatca tctgatgaag ttgaagtaga cgttacagtg acagatactc gttccgatgc
      241 agataaatat aatcctgaag gacaaaaagt gactacagac ttaaataaag agccagatgc
      301 atctgaggga attaagaaca aagaagatct accaaaagga actacttata cttggaaaga
      361 aaaagtagat gttagtacag ctggaaacaa aaaaggtact gtagtagtaa catatccaga
      421 tggatctaaa gaagaagtag aagttactat ttctgtagta gataaaaaag caccgaataa
      481 acctcaagtt gatcctatta cagagggtga ccaaattgtt actggtaaaa ctgaaccaaa
      541 tgcagaggtg acagttacat taccagacgg aagtcaacac catgggacag ctgataaaaa
      601 tggtaatttt acagttaaag ttcctaaatt agaggcaggg acaaaagtga tagtaactgc
      661 aactgatgaa tctggtaata ctagtgaacc tactaatgta gttgtttctt ccaacaaaaa
      721 agacagtgga aaaaacggta gtaaaggtag taagactgac aatcaaggta gcaacagcaa
      781 tcaagacaaa aatagaggca aaagccagtc ctcaaaagtt tttcctaaga cgggagagag
      841 tgacagtaat atctttacta ttagcggtgg tttaatactg ttaggaacgt taggattatt
      901 agggtataaa aatcgaaaaa aagagaatga atagaaaatc aatttcttaa gtcttctctg
      961 agaagaggaa gaatcttttt cttcctcttt ttgctttttt atgatgggaa ataagtgtta
     1021 gttaaagatg aatatacttt ttatagaaag gaaaagaatg taattaagtg gaaaaaatag
     1081 taattattgg ttcaaaccat tcagggctag ccgcagctcg atttctaaac ttaagcgatt
     1141 caaattatga agttattcta atcgataaaa aatcagaaat tagttacttg gaatgtggga
     1201 catcgttatt tataaaagga gaagtaagta atttagaaga tcttttttat caaaatagaa
     1261 tgacactaaa ttctgagata aaaaagttat ttctagagac agaagttgac aaaattgata
     1321 ttcaaaataa aaagattagt tgtgtaaaaa aagatggtac aagattctct caagaatatg
     1381 acaaagttat attagctaca ggttcaaagc aaattatgct agatataccg gggaataatt
     1441 tagctaatat tttttcgata aagaattttc caaatgcaaa agagattttt aaagctttgg
     1501 atgatagtac tattaaaaaa gtaggaatta ttggagcagg atatattgga gttgaaattg
     1561 ctgaagccat aagaaaaaga gggaaagaag tatatctttt cgatgttgca gatagagtgt
     1621 tgtcgactta ttacgaccgt agtttttcag ataaagttga agaaatacta tcaaaaaatg
     1681 gaatacatct ttgtctatca gaaagtccta aaaaatattt aggaagaaaa aagattgaaa
     1741 aaatagtcac tacaagtggt acccaatact ctatggatat ggtcgtacaa gctataggat
     1801 ttctatctaa tagtccaatt ggggaaaagg aactcttgag agatgttagt ggagcatatc
     1861 taactaatga ataccagcaa acaaatataa aagatatata tgctattggg gattgtgcta
     1921 caactttttt tacgtccatt aatagaagta gtgttgattt ttctatttct aatgctctaa
     1981 gaacagctta tattgcaact caacatatta acaatcaaga ttttacacct tctggttccc
     2041 aatttacaaa tggcttttct atatttaatt acaattttta cgcagcaggt ttgaatttaa
     2101 aaacagcacg attattaagt gagtctatag attatataga aatagaagat ttcattagac
     2161 ctgctttttt gagaaaaaat agtcgtgtaa aattaagaat tagctttgaa aaaaatacaa
     2221 agagaatagt aggtgtacaa ctttgtagtc aagaagattt atctggacta ttatcaatgt
     2281 tttctct
//
LOCUS       DARBDN010000184         2270 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000184 DARBDN010000000
VERSION     DARBDN010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.189"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            155..>2270
                     /gene="acm"
                     /locus_tag="SCH06_002835"
     CDS             155..>2270
                     /gene="acm"
                     /locus_tag="SCH06_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HEG1079348.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLL"
BASE COUNT          889 a          346 c          444 g          591 t
ORIGIN      
        1 ttttggcata tttatttttt ataaatattt gtaaaataac tatcaatttt ttagttaaaa
       61 gattggaaat gagtggggga ggaattgaag aaaggatttt tgagagatga tatagtaggt
      121 tttattttta gttaaaatag gggagataga aaaaatgaaa aagtgtagaa atattatttt
      181 atcaatgtta tttattatta ctaatataac atcactgatt cctgttcatg tctatgcgga
      241 tgcaggcaga gatatcagca gtaatgtcac ttcgttgacc gtggacccaa cgaatattac
      301 agatggagga aacataaaag taaaattctc gtttgacgaa aaaaaacaaa atatccaacc
      361 aggtgattat ctttggatca attggccaag tgaaggaaat attcgcggtg aaggattcca
      421 aaaagaaatc ccattaatga ttgaaaataa aaatgttgga actttaacgg tcagaaaaga
      481 ttctgcgcag gttgtgttta atgaaaatat taaaaaccta gactcagtag aaggttgggg
      541 gcaatttgag atacaggcca gaaacgtaac cgataccggt gaagaaaata cgggaccatt
      601 caccgtgacg agcggtgata aaacagctac tgtaaatgtg acaaagccag cttctggttc
      661 ttcttctagc gttttttatt ataaaacagg agacatgcta cctgaagata ctaagcacat
      721 tcgatggttt ttgaatatta acaataacgg cacttatgtt gaacaaccag ttaaaatcag
      781 tgatgaaatc caaagtggac aaagattaga tccaagtacg tttgaaatta atcaaataca
      841 cttaggtgaa cagaaggttt atagaggaga agagggaatc caacaatttt tacaagattt
      901 ccccagcgct acatttaatt tttcagtaac tgataattac attgaaataa ctataccaaa
      961 aaactttgtc aatcttagga aaataatggt gagttataag acgatcatag aaaacccaga
     1021 acaaataaat tttgagaatc attcggaagc ttggtttaaa gaatttaata aacctgctgt
     1081 tgatggagaa agtttcaatc atacagttaa aaatatttca gcttctggtg gagtcaacgg
     1141 tacagttaga ggcgaattga agattttcaa atatatcaat gacacagaga ttggtatccc
     1201 aaatgtgact ttcgaattaa gacgagcaga tgaacagcct attcaaggac agtctagtat
     1261 cctgttgact tcgaatgaac agggagaagc tagtatcaaa ggcctgcaag taggagacta
     1321 tgttgtaaaa gaaaaagaag cacccaattg gattgatttt gatccactaa gttcaaatga
     1381 actcaaattc tccataaacg aaaatgatac agagggagtc agtttaccta tttataacaa
     1441 gaaaaaggtt acgaacatca cagcaactaa aatttggaac ggtggaacca ctccaagacc
     1501 gagtatttat tttaaattat tcagagcaag tacaaacaat tgggaaccag ttcctgatgc
     1561 agaaacaaaa cgattagaca atggaataac ttcagtgact tgggaagata tccaacagta
     1621 tgatgatagt ggaaacgaat atacgtttaa agtgcaagaa gtagatcaaa acggaaatga
     1681 ttatgtccct tcaggttatc aaaaaattga aaacgggcta gtcgttacaa atgagaataa
     1741 agaagtcatt tcagtctcag gacaaaaaac atgggaagac aatgagaacc aagacggcaa
     1801 acgaccgacg acgatcacag taaatctatt agccgacggt caaccgatcc aacacaaaga
     1861 agtaagtgaa aaagatgatt ggcgctatcg tttcacaaat ctgccaaaat acagagacgg
     1921 gcaagaaatc atctatactg taacggaaga caacgtgccc gaatacagta cgacgattga
     1981 cgggtataac atcaaaaaca gttatacacc ggaaaaaaca aatatatcta taccaggtag
     2041 ccatataaca ccgtggaaaa attttccaga gaagacagag agagagaaaa ttagaaatct
     2101 attctctcaa aaattgcaaa tatttgctca tacaggagaa tccagcgaac aaagaagcaa
     2161 ttatattagt aagagagctg tacctaaaca gataacaaat aaatcaaaaa gcattcttcc
     2221 taaaacaagt agtaaaaaat ctagttttgc tgtaatcatt ggtttattga
//
LOCUS       DARBDN010000185         2242 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000185 DARBDN010000000
VERSION     DARBDN010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.190"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..750
                     /locus_tag="SCH06_002836"
     CDS             <1..750
                     /locus_tag="SCH06_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079349.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTIIEHLWKYF"
BASE COUNT          812 a          295 c          453 g          682 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      661 attcaatctg tcgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaacg
      721 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
      781 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      841 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      901 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      961 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
     1021 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
     1081 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
     1141 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
     1201 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
     1261 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
     1321 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
     1381 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
     1441 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
     1501 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
     1561 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
     1621 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
     1681 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1741 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1801 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1861 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1921 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1981 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     2041 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     2101 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     2161 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     2221 agttagaaaa ataaaaaggc at
//
LOCUS       DARBDN010000186         2233 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000186 DARBDN010000000
VERSION     DARBDN010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.191"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..544
                     /locus_tag="SCH06_002837"
     CDS             <1..544
                     /locus_tag="SCH06_002837"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEG1079350.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(900..1472)
                     /locus_tag="SCH06_002838"
     CDS             complement(900..1472)
                     /locus_tag="SCH06_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079351.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1488..2093)
                     /locus_tag="SCH06_002839"
     CDS             complement(1488..2093)
                     /locus_tag="SCH06_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HEG1079352.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          701 a          454 c          338 g          740 t
ORIGIN      
        1 catttcaaaa gagaatctct taaatcagga cttttctact gaaacgatct gtgagaaatg
       61 ggcagctgac attacgtaca ttcctactaa gaaaaatggt tggtgttact tatcttcaat
      121 catggattta cacacgaaaa gaattattag ttatacattt tcaaaacgaa tgactgtgga
      181 ttgtgtcatt caaacattga ataaagcaaa aatacattat cacattccag aaggaatgat
      241 tctacacact gacttgggca gccaatacac agcaagagaa gtggaacaat ggcttaaaac
      301 caacaaaata aggcattctt atagtagaaa aggaacacct tatgataatg ctggaatcga
      361 atctttccat gcctcattga aaaaagaaga agtctacacg actagctact cagattttga
      421 agaagcaaat cgagcgctat ttagctacat tgaaggattt tataaccgaa atcgaatcca
      481 tagctcgatt cactatctaa ccccacagga atttgaagaa ttagcaaaag aaaaaatggc
      541 ttaaccgtct ctactaaaga caatcaacac cgtagggata tggagataaa atcaatagag
      601 tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac gtgacttacg
      661 ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata tatgatggta
      721 tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta cagttaccat
      781 acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac aacatgctaa
      841 tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag acttcttttt
      901 taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa accggttata
      961 gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg cctcttcttc
     1021 ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt tcttgcaaac
     1081 atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc tacactcaac
     1141 aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag attcaaaacc
     1201 ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc tctcgtgtta
     1261 cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag accagccaac
     1321 agctgattga attttggccg atcccgtttt gtacccgtaa atttttctga aaaaatattc
     1381 ttcttctcta cgcagttctc aagcaactgt tgaatttgtt cttttgtact ttgagaagcg
     1441 gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta caaatcatct
     1501 atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt catatataac
     1561 tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat ttccaaatcg
     1621 tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa gttccaatct
     1681 acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt acttcggcca
     1741 tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat aatctcttca
     1801 aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata cataactggt
     1861 gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc aaaatcgtaa
     1921 atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc aacttcgatt
     1981 tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag tttttcttca
     2041 accttagcca actcaacttg attggttaat cccaatttat tctctaaaat catgcgaaat
     2101 ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata tcgcgatttt
     2161 gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa gtgtctctat
     2221 tttgcacagt cta
//
LOCUS       DARBDN010000187         2206 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000187 DARBDN010000000
VERSION     DARBDN010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.192"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..914)
                     /locus_tag="SCH06_002840"
     CDS             complement(<1..914)
                     /locus_tag="SCH06_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HEG1079353.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="SCH06_002841"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="SCH06_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEG1079354.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="SCH06_002842"
     CDS             2006..2176
                     /locus_tag="SCH06_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079355.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT          747 a          384 c          422 g          653 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaagaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataa
//
LOCUS       DARBDN010000188         2205 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000188 DARBDN010000000
VERSION     DARBDN010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.193"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(149..619)
                     /locus_tag="SCH06_002843"
     CDS             complement(149..619)
                     /locus_tag="SCH06_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079356.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            706..1404
                     /locus_tag="SCH06_002844"
     CDS             706..1404
                     /locus_tag="SCH06_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HEG1079357.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            1582..1923
                     /locus_tag="SCH06_002845"
     CDS             1582..1923
                     /locus_tag="SCH06_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079358.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            1916..>2205
                     /locus_tag="SCH06_002846"
     CDS             1916..>2205
                     /locus_tag="SCH06_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEG1079359.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTET"
BASE COUNT          805 a          315 c          445 g          640 t
ORIGIN      
        1 gcaagcgttg ataggaacga ttgtttacat ggtttggatt tttatggggc ttgatgaagc
       61 tgaagctgag tacagagcga aaaagccaac cgagggggct gactaaaaat gaatagaaaa
      121 gagaaactag aatgtatatt actattactc agtttaattc tttcactaat ttctctattg
      181 ggaagtttgt atttttgata tcaacaattt tgtggatttg ggttctattt agagtaaata
      241 tcatttttgt ttggtgatta aggagtttat taaaattaat tttccctact tcaaatgcaa
      301 ggtaacaaga tatagcactt ttaggaggaa tatttagcgg tacagcttca gagtatattc
      361 tattatcatc gactgatcct cctttagcaa ttaatttctt aaatggagta gctgaccatc
      421 tgcggtttaa gttagcggat gaaagttcta aattaactaa catagctggt tctgttgaat
      481 agttagaaat gattactttt gtataaatca tatctgcagc gaagtaagaa gcattaagtt
      541 caacttctag ttgagggcgc attcctttta tttttatccc tgttaaaaac gtactcaata
      601 taaaacttat tattgacatc cattgaaaaa ttgttaagtg aaaaaaattc aaaataaaca
      661 ccaccagttt ttaactaaat tataccaaaa aggagagaag aaataatgca agaattagta
      721 attttgaaaa ataaagaagc tgtgactacg agcttacaag tggcagaaag cttcgagaaa
      781 aaacatcaac atgttttaag agatattgat gcactaaaaa aagatgtgtc caattttgga
      841 cagatgtttg tagaaggtaa tgaaccagat tcatatggca gaaatcgacg agttttcttc
      901 attagtagag atggattttt cttgctggct atggggttta caggaaagaa agctatctac
      961 ttcaaacaaa aatacattga agcattcaac gaaatggaag atgttattcg caagaatact
     1021 gttcctcaaa caattgaaga tatgatgatc tatcaattag aagaaatgaa agatgttaaa
     1081 aaagatgttt ccatgcttaa agatactatg cgaattagcg gacaacaaga gtttgaaatt
     1141 aagcaaaaag gaaatatgaa agttatggga gttctagggg gaaaagaaag ccgagcttat
     1201 gaagaaatca gcaaaaaagt attctcaaaa ttttggtctg aatttaaacg taccttttca
     1261 atcccaagat atggcgagtt acctcgtaag agattcgatg atgctgtttc atttattgaa
     1321 atgtggttgc cagaaactgc gatccgtatg gaaattgatc aactgaacag acaacagaga
     1381 ctttttggtg atgacaatga atagagctga agcgctaaga atagggacgg caattgctaa
     1441 ttgctggtgg aaatactata aaccaatcat cctaagccaa caacatattg acaagcaaaa
     1501 agcatggcaa caaataaaaa agtgactccg ccggcaagca aagagtcaca aagaaaacac
     1561 atcataagga gattttagca tatggaaaaa gaactttcca ctctagatca atatttgatt
     1621 gatcctgatt ggggcaagcc gaaaattgag gaaacaagtg gtcgaaaaat cagacgaaat
     1681 cttttgacga atgaagaact agcttgggat caagatgatt taggcaacca tgtaactatt
     1741 tgggatcatg tttatcttat ccatctatcg aagcattcga ataaacctga atatatttac
     1801 gtcatcgaag atggcttgat tgatgcgcta gaagagtacg acagagataa cttgattgat
     1861 atctcttatt acggaccagg taagaaatac attgctgaaa tggaggcaga atttgatgag
     1921 tgaaatcaaa gggacaacga actttgaaaa actttttagt cgtaagttaa ataaaattct
     1981 caagaaaaaa ggaaattttg attatttatc ttgggctcac gcgtgggaga ttatgaaaaa
     2041 gaatgatcca caggcaacgg taactattaa tgagtacaaa cactacaggg ttgtttctgg
     2101 aactcatcaa gactttcttg ttgaggaata taaacctttt cttatggatg aaactgggac
     2161 ttatgtatct gtctcagtaa cggttaaagg acacacggaa accga
//
LOCUS       DARBDN010000189         2143 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000189 DARBDN010000000
VERSION     DARBDN010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.195"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(326..547)
                     /locus_tag="SCH06_002847"
     CDS             complement(326..547)
                     /locus_tag="SCH06_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079360.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(645..890)
                     /locus_tag="SCH06_002848"
     CDS             complement(645..890)
                     /locus_tag="SCH06_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079361.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1130..1744
                     /locus_tag="SCH06_002849"
                     /pseudo
     CDS             1130..1744
                     /locus_tag="SCH06_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          722 a          375 c          302 g          744 t
ORIGIN      
        1 tcattactct gtcctctctg tcttttttct caattttaca ctaaaataga ttttttggaa
       61 aactttgcaa cagaaccgtt tttactatat acttcttccc agaacttgtc cgtctccttc
      121 aaattatctc tacctctcga gttcattggg tggtttgccc atttattaaa catggaatca
      181 cctttctcat actcatatat ttatgtccta tttcaattat atttatatat gcttaaataa
      241 atttgtatcc tgaaatttat tgtaatatga agctgtattt tacatatagt aaccaaagag
      301 ttaataaaat aaaaagagcg aaccattata gatcagctct tttttcattg ctgtttttaa
      361 tcttatctag aatcacttca aatgtttcaa aggtatttac atctaactga cataaccaaa
      421 gcaagtactt cttttctttg taagtccaat caatattacg gtaagaggac attagattat
      481 ggtaccttgc tctttgttca actgaagcca attcccagcg tttttcaaat attttttctt
      541 cttccattat tgatccctcg caagacgcta cctcaaactt aaataatggg cagcgaaagt
      601 ctaattcctt agatctaagt atagcaaaca aatatgaaaa aaacttagaa ggtagtaaaa
      661 gttcttccgt cttttgcttt gcttctattc ttaatgtgtt tcgttatcgg tgccctacaa
      721 agattttcat taattacaca ctcatttatt gttgtgtatt ttctgacatt tctctcttga
      781 tcaattattt taattccatg ggcatcctga tagttcatag gagaggagcg gctatcagaa
      841 atagttgcac ctatctcttg aacttctttt acaacttctg gaaaatccat ccatcctgct
      901 tcagctgtca aaagtaataa tctataatat ttatctttcc ttttcaatct aagaaatcgt
      961 caccccattc tttttcttct attataaact atttaacttt tagaattcaa aaaccgtttg
     1021 tctatttaga gtttacccta aatagacaaa aatataacat tgaaaaattt agagttctaa
     1081 cgtatgatta gggtgtatta taaacgttat agaaaagtag ggaataaatt tgaaaattgc
     1141 ttatattaga gtttcatcca tcgatcaaaa tgaacaacgt caaattgaag aaatgaaaaa
     1201 gtttggcgct gaaaaaattt ttatcgaaaa acaatctgga gcgacgatta gtcatcggcc
     1261 gattttccag gaagctttag attttgtcag agagcaagat atttttattg tagaagccat
     1321 tgatcgactt ggacgcaatt atgacgagat tatcgattca gtgaattatc taaagaagaa
     1381 gaatgtgcga cttattatca ccagtttacc gatcatggct gaagcaattg gaaatcctct
     1441 cctagataaa ttcatcaaag acttaatcat ttaaatctca gccatgattg ctgaacaaga
     1501 acgtactgaa tcgaaacgac gccaggcaca aggaattaaa atcgctaaag caaacggcgt
     1561 ctataaaggt cgtcctaagt tatacagtgc agacaccaaa gatcctcaac gtcgccttgt
     1621 ctataggagt atcgttcagg atcttgagaa tggggttgct atctcaaaga ttgcaacaga
     1681 ctacaatgtg actaggcaaa caatttaccg aataaaaaaa gaaatcgacc aactaattgt
     1741 atgatttctt ttttgaatca cgtaattatt aattagcttt gtcatcaata cagacaatca
     1801 ttttagattc atctagctaa gttgattaca tttatgttaa aaagaattta gttaacataa
     1861 atataattga tgcataaatc gtccttattt aaaggcattt aacattgaca acttagtata
     1921 atgtatctta tgtaaactaa taagatttga attttatttt atacacactc gataatagat
     1981 caattttatg gtcccccgca tttacgattg cacaagagaa acataaagtc gacctattag
     2041 catttctttt caattcaaac attaaaaaag tttatacctc tgctactaaa aaatgaaatt
     2101 atctatttaa aatttaaaac ggtaaatctg attcatccaa att
//
LOCUS       DARBDN010000190         2105 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000190 DARBDN010000000
VERSION     DARBDN010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.196"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..538
                     /locus_tag="SCH06_002850"
     CDS             <1..538
                     /locus_tag="SCH06_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEG1079362.1"
                     /translation="QTFVMGHIGRISYSKNHRFLIEIFKEFHAIKNNSVLLIIGTGDM
                     EEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLFEGVPLVGIEAQFADLP
                     CFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRDSERSILIKADYNIQTA
                     YKILESKYYELFELIQRG"
     gene            544..1566
                     /locus_tag="SCH06_002851"
     CDS             544..1566
                     /locus_tag="SCH06_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HEG1079363.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            1588..>2105
                     /locus_tag="SCH06_002852"
     CDS             1588..>2105
                     /locus_tag="SCH06_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1079364.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMS"
BASE COUNT          824 a          227 c          408 g          646 t
ORIGIN      
        1 tcagacgttt gtaatgggac atattggaag aatttcatat tctaaaaatc atcgtttttt
       61 gattgaaatt tttaaagaat ttcacgctat taagaataat tccgtattat taattattgg
      121 aactggtgat atggaagaag aaataaaaaa ttatgcaaag aaaagtggca tagatgatga
      181 tattaaattt ttaggaaata gaaatgatat agaaaaattt tatcaagcat ttgacgtatt
      241 aatgttgcca tcattatttg aaggggttcc gttagtgggt attgaagctc aatttgcaga
      301 tttaccgtgt ttcttttcgg agaaagttcc tacagaagtt gctttcagtg ataagaccaa
      361 tttcataagt ttaaatcaat cggcaaaaga atgggcgaga gagattgcaa atgtagatat
      421 ctctcatcga gattcagaac gttcgatttt aataaaggca gattataata ttcaaacagc
      481 atacaaaatc ttagaatcaa aatattatga gttatttgaa ttaatacaaa gaggttaaag
      541 aatatgacac agaaacattc aagtataaaa agaattatac atcgcatatc cgaagaattg
      601 aatgcaacaa gacgaattgc aaagataaca tcttggaagg aagcatttgc cacgttacaa
      661 gctaaaattg atattcaagt catgaatcgt aatggatata atgaaagtaa aaaacagaag
      721 gaacatttat taaaaaaaca tgaggtaatg ctgaagtatt atgaaaagac tttttcagat
      781 tttttgaaaa catatgatta tagtcaaaat caaataatta atcaatcaaa atcaccatat
      841 tctaactgca tttgggtttg ttggtggcag ggattggatc aatcgccgga aattgtaaaa
      901 gcttgtgtaa aatcaataaa acgaaatgca gggaaacata ctgttataat tttaacagaa
      961 gataattata gacaatatgt tgatatacca aaatgggtgg aagaaaagaa aaacaaagga
     1021 atcattacga gaacaaatta ttctgattta ttaagattat ctttgctagc aaaacatgga
     1081 ggtttgtggt tagacgccac attttattgt acaaaaccaa taccagatga gtattttgat
     1141 atcgatattt ggtctattag gaggcctgat tatgctcacg catccgtagc atcaggatat
     1201 tttgcgggtt attcattagc atgtaatcaa gagtctagat ggatgtttgc tataattaga
     1261 gacttttttt taaattattg gaaaaataat gatatgatgg tggattattt gatgatagat
     1321 tatatgattg ttttagcaca gagaataaat catgaaatag cacagacatt tgataaaata
     1381 cctagtaaca atccattatg tgacgaattg attaaaaatt taaataatat atatgatgaa
     1441 aaagtatgga acttattaaa gaaagatact ttactgttta agttgacatg gaaacaatct
     1501 tttaaaaagc aaaaagatga taaagttact ttttatggga tgttggtaga aaacaaatta
     1561 ttataaatat tagaggtata aaaagttatg aaacacaagg taagtgtgat agtaccaatt
     1621 tacaatgttg aaaaatattt aagaaaatgt gtggatagtt tattgagtca gacattaaaa
     1681 gagatagaaa tcgtattagt tgatgatggt tcgccagatg cttcggggga aatagcagat
     1741 gagtatcaaa aaaaatattc taatgtaaaa acaatacata gagaaaatgg ggggttagga
     1801 ccggcaagaa atacaggaat tgagaatgcg acaggagaat atgtggcttt tcttgattca
     1861 gatgattggg tagaaagtga tatgtatgaa aaattatact tagttgcgtc caaagaaaat
     1921 gctgatatag tagttagtgg acattgtgat tttgcgaatg acaaagctat ggtgaaaaag
     1981 caacatcctt tgagtgggaa tgtatatgat acgcctaata gtattaaaaa tgtacgaaaa
     2041 aatttatttg gacatagtcc aaaagatcaa gaagtagagg ccttcccgat gtcagtatgt
     2101 atgtc
//
LOCUS       DARBDN010000191         2065 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000191 DARBDN010000000
VERSION     DARBDN010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.197"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1008
                     /locus_tag="SCH06_002853"
     CDS             <1..1008
                     /locus_tag="SCH06_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079365.1"
                     /translation="LLDAPYYLSKVALGENLIKPESQQPVTNSNYLINTYNIKPMVKG
                     KKYTITLEGTKPATQVFRPFFTRATGDAWEVGDLQPVEGLTDVWSGTFTAAADPHPTS
                     PQVQICQVPSTSLGNCTIKWLKLEEGDTRTPNIEQYKYRGIGMRDSNNPKDYVWDLAP
                     EYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANAT
                     AIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGRSSGGNDST
                     ILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYT
                     I"
     gene            1025..1174
                     /locus_tag="SCH06_002854"
     CDS             1025..1174
                     /locus_tag="SCH06_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079366.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            1171..1617
                     /locus_tag="SCH06_002855"
     CDS             1171..1617
                     /locus_tag="SCH06_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079367.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            1619..1756
                     /locus_tag="SCH06_002856"
     CDS             1619..1756
                     /locus_tag="SCH06_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEG1079368.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            1794..>2065
                     /locus_tag="SCH06_002857"
     CDS             1794..>2065
                     /locus_tag="SCH06_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079369.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKT"
BASE COUNT          753 a          358 c          425 g          529 t
ORIGIN      
        1 ctacttgatg caccgtatta tttgagtaag gtggctttgg gtgagaatct aattaaacca
       61 gaatcacaac aaccagttac taatagtaac tatcttatta acacctataa cattaaacca
      121 atggtaaaag gtaagaagta taccatcaca cttgaaggaa ctaagccagc aacacaggtt
      181 tttagaccat ttttcacacg agcaacagga gatgcatggg aggttggtga cttacaacca
      241 gtagaagggt taactgatgt ttggtctgga acatttacag cagcagctga cccacaccct
      301 accagcccac aagttcagat ttgtcaggta ccaagcacaa gtttaggaaa ctgtacaatt
      361 aaatggttaa aactagagga aggcgacaca cgaaccccga atattgagca atataaatac
      421 cgaggaatcg gcatgcgaga ctcaaacaat ccaaaagatt acgtctggga tctagcacca
      481 gaatatgtcg aagacaatct ggccacagat attaaaattt ctgaaattac tggtaaagca
      541 aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc ttcaattaat
      601 gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc gactgctata
      661 gatgaattag acaataagat cgatgaacgc attaatgata cagctactac cacattaaca
      721 gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac agtttctata
      781 tattttgtgg ctttaaacgg aagaagcagt ggtggaaatg attcaacgat actaacaatt
      841 ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat agaccgttct
      901 actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg gcgaagaaac
      961 tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa aagcgtgaat
     1021 cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa tcattgtgaa
     1081 tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc caaattggaa
     1141 accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata tggacgtact
     1201 ggcggagagt acgcaggaaa agtattggac gacatgcttg tatccgttcc ttacacagat
     1261 cagccaccgc ttgaaggaat tcgtgctgat ggcgaaccgt taacaatcgc tgatcaaatg
     1321 tttgatccta aattgaatca atggattatt ttagcgaacg cactagatca caacgattta
     1381 aacaatctca aagcaatgta tgagtcgtta gaaaatgaga acggcgattt aaaacagatc
     1441 aatgccaaac tcatgctaag cgatgtagca attaaacagg aaaatactgc attgaaagaa
     1501 aaagcggata gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt acaaaatagc
     1561 aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg tgagtagtat
     1621 gtttagtttt agcgatgtga aaatgatgta tgattggggc tgtttcacta acgaacaagt
     1681 aatggttttc gttccgttgt gcattactga agaaaaagca gataaaatca ttagcaaaga
     1741 agagagcgca tcttaattga tgtgcttttt attttgattc aaggagttgt cacatgatta
     1801 atttagggga atggggagcg atagcaggat caataaccgc tatcgtttct ttgattttat
     1861 tagtaataaa accaattact gcatctttct cgaagattac tgagactctt tcaaaagtaa
     1921 gtcacaattt agatttgctg actaaagatt tagaatcgag caaatcagat cgattgatga
     1981 ttcatgaaga actaaagaaa cacgatgaaa gattagatac acatgcagaa aaattggtag
     2041 aacacacgca acaaattaaa acttt
//
LOCUS       DARBDN010000192         2060 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000192 DARBDN010000000
VERSION     DARBDN010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.198"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..268
                     /locus_tag="SCH06_002858"
     CDS             <1..268
                     /locus_tag="SCH06_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEG1079370.1"
                     /translation="KIIEIHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVK
                     EMPESANDMYEKELKYFFENVVTGKENWNDLYHANEVLKIAEEK"
     gene            269..1021
                     /locus_tag="SCH06_002859"
     CDS             269..1021
                     /locus_tag="SCH06_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEG1079371.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            1026..1973
                     /locus_tag="SCH06_002860"
     CDS             1026..1973
                     /locus_tag="SCH06_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEG1079372.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          725 a          271 c          403 g          661 t
ORIGIN      
        1 taaaattata gaaattcatt tagattattt tggaagagtt cctacaagaa aatttcaatt
       61 gtttacttta gatgaatgta tcaatgttga cttattaaat aataaaataa gttttgaaga
      121 aaacattgtt aaagaaatgc ctgaatctgc taatgatatg tatgagaagg agttgaaata
      181 tttctttgaa aacgtagtaa caggcaaaga aaactggaat gatttatatc atgcaaacga
      241 agtattgaaa atagctgagg agaaataaat ggaaatttta tttactattt gtggtagagc
      301 tgggtctaag gggtttaaaa ataaaaattt gaaatatttg gcaggaaagc ccctagtcca
      361 tttcgcttta gcaatgatag atatctatca acaaaaacat cctgaacata attgcacgac
      421 ttgtttgaat acggacagta atgagttagt agaattgacg actaagttaa atccgtctgt
      481 gaaaattgta gaacgtaaac ctgaattagc tacagatact gtagggaaaa ttgaagtgat
      541 acgtgattca ttcttacaac tagaaagaga agataatata tttgatttaa ttatagattt
      601 agatttgact tcacctttac gtgaagtttc taatcttgaa gaattaatag atgaacatct
      661 aaaaaattta gataaagacg tctacttttc agttgtttct gcaagacgta atccctattt
      721 taatatggta aaaagaattg aaaatgaagt tactatagtt aataaatcaa gatacacatc
      781 taggcaacag acacctgaag tttttgaaat gaatgcctca atgtattctt ttaaacctga
      841 atttctaaaa aaaagtaatt atatttttga tgggcaatgt gggataataa aaatgagaga
      901 ttatctaatt ttagatattg atagtgaaga agattttaaa tggttagaat ttttgtttcc
      961 taaattttta gaagattctt cggagcttca agatatctat aattatttat atcggaggta
     1021 aaaggatgag ctgttatctt atcaccggtg gggctggctt cattggttct accttagcca
     1081 atcatttagg agaagaacat gtggtaatcg tcgtcgatga cttatcaatg ggaaaagtag
     1141 aaaatcttga tatgacgaaa aatatcactt ttattgaggg agatgtcgct gagaaatcct
     1201 tgatggaaga gatcatgaaa gctaataaat ttgattatat ctttcattta gcagcagttg
     1261 ctagtgtggc agattcagtt gcccgaccag tagaaacaca tcgtgtgaat tttgaaagtg
     1321 tattaatgat tttagaattg atccgcaagt atcaacctga tttaaaacgg atcgtgttta
     1381 gttcttcagc ggctgtttat ggggatgaac cgactttacc aaaaaaagaa gagtccgtga
     1441 ttcgcccatt gacgccttat gcggttgata aattcgctgc agaacaatat gtgctagatt
     1501 attgtcattt atatgatgta cccggtagcg cagttcgttt tttcaatgtc tatggtccaa
     1561 atcaaaatcc gaattctcca tacagtggtg tgatttctat tctcgtagat cgctataaga
     1621 aacaaatcgt aggagaagca acttcattta cattatttgg tgatggaagc cagtctagag
     1681 actttgttta tatagatgat gtaatccaag cattactttt agttgcgaat gaggaagctg
     1741 cactggggaa acaattcaat gttggaacgg gtaaagcaac cacacttttg gaattgattc
     1801 atgcaatcaa tgaaattctc ggtgtagaat tgacacttga atacaaagaa gagcgttcgg
     1861 gtgatatcca tgactctcta gcagatatta ctaagatcca gtcaattggc tatcaaccga
     1921 aatatggtat tttaagtgga atgactaatt atttgaaaac tgaaatcaat taaaacatac
     1981 taagataaga ttagagggta aattcaggct ctttgtcaat aaggactgat gagttttgta
     2041 aaatcaaatc tgggatagaa
//
LOCUS       DARBDN010000193         2057 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000193 DARBDN010000000
VERSION     DARBDN010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.199"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..338)
                     /locus_tag="SCH06_002861"
     CDS             complement(<1..338)
                     /locus_tag="SCH06_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEG1079373.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAK"
     gene            complement(405..560)
                     /locus_tag="SCH06_002862"
     CDS             complement(405..560)
                     /locus_tag="SCH06_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEG1079374.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
     gene            1177..1398
                     /locus_tag="SCH06_002863"
     CDS             1177..1398
                     /locus_tag="SCH06_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079375.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            1399..1656
                     /locus_tag="SCH06_002864"
     CDS             1399..1656
                     /locus_tag="SCH06_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079376.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1792..>2057)
                     /locus_tag="SCH06_002865"
     CDS             complement(1792..>2057)
                     /locus_tag="SCH06_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEG1079377.1"
                     /translation="DIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLI
                     DYAMSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
BASE COUNT          678 a          463 c          314 g          602 t
ORIGIN      
        1 cttttagcat attgaaattt ttctggatta tccatatgag caaaatatcg caccatacct
       61 tttgcattag cacatttttg cgggtttgga gaccgaagct tttgagttat ctcacgtatt
      121 tgatcatacg tctttttacc gctaaacatt atcaaaacat gccaatgagg ctttttcaat
      181 tcaccgtcag gattcacatc tttatcatga agtggactct caacccaagg aacatgtaac
      241 tcatctaaaa actccctcca attttcagga gccgattcag gatagactac aaacgtccaa
      301 ttccttgtgc gttcatcttt agtttttcta ctcgtcatgc tataattacc ttaattgaac
      361 aacagtctaa cagcaaaagc agtgcgccaa cactaatgct tttgctattt tttttgctca
      421 ttttcctttc cgttagcatt aacccaaatt gtaataagac cagacttact aagacccatt
      481 tgtttcgcaa ttttatcaag attatctgcc acttccttag taagcgttac aacgactctc
      541 tttttttcat tactgatcat aattcgtatc ctccaacgac tttttcttaa aaaccatagt
      601 aacaaaaaag taactaaggt gcaacagttt agatactaat tagcgaataa taggccttaa
      661 acccttggca ttactgattt tgtcaaaaaa aaacgctgaa acccttggga gagtaaggct
      721 aaacagctat cgaccaatga ccaatgacca ataagggggg tgtcgtagtc cccccctcct
      781 ccgcccaatt cataaacacc aaaaccaaaa aacaaacctc agggctccgc cccgaacccc
      841 gacctccttc taccgaaata tatgcaggcg ccacgcttac tatttcgttc agctatcggc
      901 ttttgcaatc taacacgacc gtttcgctac cagtcgcctt acaggctcca ttctcgcttc
      961 tcttacgtgt tttaacgatt gcgccgataa ctaaacgaaa tagacgctaa atcgcttaaa
     1021 acgcaaaata gacccttttt agagcattga ttttttctac tagtcatttc gataatataa
     1081 aattgaccac aacacagaaa acttatatta taagcttatg tcgtaagtcc gacgtactca
     1141 cgtaatatag acggacgtta aatggaagga gcataaatga gagtgataaa atcagaaaaa
     1201 ttcactttgg ccgaaattat gacgaccagc gaacttgcac aagaacttga ttacaaccaa
     1261 gcttacgttt tgcgcttagc gaaagaacat ctgactgaag gaaaagaata tcgctctgcc
     1321 ggtagaagaa actatctttt cagcccagaa gcccttaaaa aactagaaaa agtcataacc
     1381 accaaagaag gtgagtaaat gcctaaagaa acaactatca acgttgaaca actagaaaaa
     1441 ttgctagaat catattccaa tgattttatc gaattgaccg gcggaaaagt cgaagaaacc
     1501 accgacctct ttgacctact tctcacaaat attctggaat taaactctga agaacaaaaa
     1561 gagcataagg gaaaactgat agcaccttcc tacaggaagg tggctaagtc ggctgtgcca
     1621 actggttttc ttacaaaaca accttatatt ttttgatatc acaaaaaaat ccattttgga
     1681 cctattttcg gtcataatat agtacctact tttggtcata gtttcgtccg tagttttggt
     1741 catagtgact aagactttca cgcacaaaaa aagagctgaa attaacagct cttatccttt
     1801 atttattttt gaatttacac ttccaccatg acgattcgat tttatatatt gcccgataat
     1861 ataagctgaa ttatcacaaa gaagcggaaa ccaatcatca aatctttctg acattgcata
     1921 gtcaattaaa tctttgattt cagtgatatt cttagaatca acaaacgaca tcatctctct
     1981 aatcaactca tatcgttctg cactcgttac tgacaaataa ctagcaattt ctgcaccacc
     2041 atgagcgata atatcac
//
LOCUS       DARBDN010000194         2011 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000194 DARBDN010000000
VERSION     DARBDN010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.200"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            581..1549
                     /locus_tag="SCH06_002866"
     CDS             581..1549
                     /locus_tag="SCH06_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1079378.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1560..>2011
                     /locus_tag="SCH06_002867"
     CDS             1560..>2011
                     /locus_tag="SCH06_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HEG1079379.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFT"
BASE COUNT          669 a          299 c          392 g          651 t
ORIGIN      
        1 tttctgaata taactactgt atcaaaaaca atcgattatg agacaaaaca aaatgacctc
       61 ttttatttaa gaaaggaggt cattttttgt atcataaatt gtattaaaat caatgtatca
      121 ctttttaatc agttttaaga ccataaattg cgtactaaaa gaaattctgc aattcaaaat
      181 aaagcatttt aagccatttt caaatttaag tgcacccatc tacccgtcaa atcactttat
      241 tttccactcc agtagtttcc taattcaact gtgtgcaaaa acgatttctt ctaaacaaat
      301 caagacaaac ttataaacct tcatcccagc accataatta tttaaatcat aggcattttt
      361 cgaaattagt atatgtactc aagtttcact gcagattatt tatatttttt agagaaataa
      421 atttttccta ttgacaaaca caaagaaagc ggatacaatg caattatgtc acatgacgtt
      481 atatgacgtt atatgacgtt atgtaatatc tttacattta atcagttact tttattttgg
      541 ataaaattaa catttttaaa attttaagga ggaaatgttg atggatgtag caaaaacggt
      601 taacgcaatt gtagaaaaaa atgatggaga gatttctgga atttatttgg tggcttgtgg
      661 cggttcgctg gtagatatgt atgtctcaga ttattttctt aaagccgaag catcgaagtg
      721 tattacaggc ttatatacag cgaacgaatt taaccatgta accccaaagc aattagatga
      781 taaatctgtt gtcattctat gttctcatgg aggaaataca gcagaaacgg taaaagcagg
      841 agaagtcgct caagctagag gagctgtgac tgttggtctg actcataata aaactgcgga
      901 tttattaaag gtttctgatc atagtttcct ttacgaatgg ggagatgatg caaaaatagt
      961 caataatcct atggccatca ttcttgattt aactgtatct ttggtcaatg ttaccgaaac
     1021 atttgaacat tacggtaaat tcagagaagg catgaaggtt atcgataccg taattgaaaa
     1081 tggcattaag caggtgcagg atcgtattaa agtgtttgct gataagtaca aagatgaaac
     1141 aatgttttat atcttaggta gtggaccatc atatggacat gcttatggtt tttcaatttg
     1201 ctctttgatg gaaatgcaat ggcttgattc aacttctgtt cattctggag aattcttcca
     1261 tggacctttt gaagtaacag acaaagatac gaattttatt ctcttgatga gcattggacg
     1321 cactcgtgct ttagatgaac gggcaaaacg attccttgat aaatatgcag aaagagtaga
     1381 aatcgttgat gcaaaggaac taggattgga tatgatatca gatgaagttt ctgaattctt
     1441 caatcccatt ttattctaca gtattctttc agaatatcgt tcagctttag cagatgtacg
     1501 caatcatgat ttagatgttc gtcgctatat ggggaaagtg gagtactagg aggattaaaa
     1561 tgaaggtatt aggcttaggt gataacgtcg tcgataaata tgaaaatctg ggaattatgt
     1621 atcctggagg aaattcattg aattttgcag tttttgcaaa aaaactggga catgaaagta
     1681 gctttatggg agtttttggc tcagatgagg aggcagctca tgttttatca gcaataaaag
     1741 aaataggact ggacaacagt cactctcgct ttgaaaaagg cgagaatggc tgtgccagag
     1801 tgaagattga tgagggcgac cggattttcc ttggcagcaa ttcgggaggt gttactcgtg
     1861 aatacccgat tcagcttact gaagaagaca gagaatattt aaaccagttt gaattgattc
     1921 atatgggatt atatagccat gtcaatcatc tattagaaga gttacaaaat gtttctggaa
     1981 agatttctta tgatttttct gacgacttta c
//
LOCUS       DARBDN010000195         1992 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000195 DARBDN010000000
VERSION     DARBDN010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.201"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            274..840
                     /gene="amaP"
                     /locus_tag="SCH06_002868"
     CDS             274..840
                     /gene="amaP"
                     /locus_tag="SCH06_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEG1079380.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            853..1041
                     /locus_tag="SCH06_002869"
     CDS             853..1041
                     /locus_tag="SCH06_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEG1079381.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1054..1611
                     /locus_tag="SCH06_002870"
     CDS             1054..1611
                     /locus_tag="SCH06_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEG1079382.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1643..1885
                     /locus_tag="SCH06_002871"
     CDS             1643..1885
                     /locus_tag="SCH06_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEG1079383.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          725 a          308 c          406 g          553 t
ORIGIN      
        1 aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt aatcttgaat
       61 aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa gcaattgtta
      121 tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg gtagcgcttt
      181 atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt agagttattt
      241 acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa aataatcggt
      301 gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat caatgcgccg
      361 tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa ttactacatg
      421 caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat catcttgcta
      481 gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga agatggcaaa
      541 ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca cgaagaagag
      601 ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca tatccatgtc
      661 aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt gatgcaagat
      721 atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt ggcagtcaca
      781 tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg agtggaatag
      841 gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat ctttgggggt
      901 cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac attgttgatc
      961 ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc aggaatagtt
     1021 gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat gaatacaaca
     1081 aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg tgaattgact
     1141 tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt agatggtcta
     1201 ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa cacagataac
     1261 gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga tctagatgtg
     1321 atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga attgatcagt
     1381 actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa tgttgcagac
     1441 atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa agtaacagaa
     1501 gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa atctgctgta
     1561 ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata agaagtaaga
     1621 agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg gcggtatcat
     1681 tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca tcgcaaacat
     1741 cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt ggggaccaac
     1801 aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag tattagtcgt
     1861 ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg aaatgaagaa
     1921 caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt tatatgaagt
     1981 attctttatt cc
//
LOCUS       DARBDN010000196         1962 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000196 DARBDN010000000
VERSION     DARBDN010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.202"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..272)
                     /locus_tag="SCH06_002872"
     CDS             complement(<1..272)
                     /locus_tag="SCH06_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079384.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
     gene            complement(309..446)
                     /locus_tag="SCH06_002873"
     CDS             complement(309..446)
                     /locus_tag="SCH06_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEG1079385.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(448..894)
                     /locus_tag="SCH06_002874"
     CDS             complement(448..894)
                     /locus_tag="SCH06_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079386.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGVRSDGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYEALEHENGNLKQLNAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(891..1040)
                     /locus_tag="SCH06_002875"
     CDS             complement(891..1040)
                     /locus_tag="SCH06_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079387.1"
                     /translation="MKVVYKSIKPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            complement(1054..1386)
                     /locus_tag="SCH06_002876"
                     /pseudo
     CDS             complement(1054..1386)
                     /locus_tag="SCH06_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2479 domain-containing protein"
BASE COUNT          509 a          407 c          342 g          704 t
ORIGIN      
        1 aaagttttga tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa
      181 gatgcagcaa tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcattc cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa
      301 cgcatcaatt aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta
      361 atgcatagtg gaacgaatag tcgaacttga tcgtcagtaa aacagcccca atcatacatc
      421 attttcacat cgctaaaact aaacatacta ctcacctcct tttgaagctg gatttagttg
      481 ctctttaatt tctgaaatgt ctttgctatt ttgtaacgaa gcaagcatca tttttgaatt
      541 gatttgtgct aaactgtcag ctttttcttt caatgcagta ttttcctgtt taatcgctac
      601 atcgcttagc atgagtttgg catttagctg ttttaggttg ccgttttcat gttcaagagc
      661 ctcgtacatc gctttgagat tgtttaaatc gttgtgatct aacgcgttcg ctaaaataat
      721 ccattggttc aatttaggat caaacatctg atcagcaatc gttagcggtt cgccatctga
      781 acgaacccct tcgagcggtg gctgatctgt gtaaggaacg gatacaagca tgtcgtccaa
      841 tacttttcct gcatactctc cgccagtacg gccatatttc caaatgtttt tcatttattt
      901 ccctcccagt aattgaattt cggtttccaa tttggaatcg gtggttcgac ttctgtgcat
      961 tcttccggta aatgttcttc gtcattcaca atgatttgct cgaatccgta aggcttgatt
     1021 gatttgtaaa ctactttcat tagatttcct cccttaaatt gaataagtga taacaaatga
     1081 ataagctgat ccataacttg agtttcttcg ccatttaatg gctccatctg caccaataga
     1141 taactgagca ctgttcaaag tagaacggtc tatcgagcca accagttgct caaaactaat
     1201 tggtggccga tagccttctg gaattgttag tatcgttgaa tcatttccac cactgctttt
     1261 cccattcaac gcaaaaaaat aaatagtgac ggtttttcct tcacgataaa gctttgctga
     1321 tccggtattc ccgtttgtaa ctgttaaggt tacgacttca tatttgttgt cgtctgatgt
     1381 caatacagat tttccttttg attgaatacc atcttcgaaa tttttcaatc cttcgatgga
     1441 ttgcggttca gtcaaactaa ccgtatcatt caagcctttt tcagtatatt caggcgtgat
     1501 gtcccagctg tagtcgttcg gattgttgct atctttcaat ccttcaccaa agtatttaaa
     1561 ctgactaata ttcggggttc gggtgtcgcc tttttcaatt ttgagccagt caatttggca
     1621 tgcgccggcc gtttctttag gcaactgaaa aatgcgaagg tctttaggca aacccggttc
     1681 aagtttcgtt ggtgtgaatg ttagagacca tacgtctgtc aatccctcaa ctggttttag
     1741 ttctccaaaa ttaacgttcc aataattata tgctacaaag gtttgacttg cgggttttgt
     1801 tcctttaagc gtgatagtat acgtttgacc tattataagc tcttcttccg tgttaccttt
     1861 atatatttcg tacgcgctag atttaattgg gaacgtcgta cctttatttg caatattctc
     1921 acccaacgat gttttaccta cccagtaagg gtcatctagt aa
//
LOCUS       DARBDN010000197         1843 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000197 DARBDN010000000
VERSION     DARBDN010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.203"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(1..608)
                     /locus_tag="SCH06_002877"
                     /pseudo
     CDS             complement(1..608)
                     /locus_tag="SCH06_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            629..1795
                     /locus_tag="SCH06_002878"
                     /pseudo
     CDS             629..1795
                     /locus_tag="SCH06_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
BASE COUNT          635 a          288 c          356 g          564 t
ORIGIN      
        1 tagcgatgga agatcgtgaa tttcttttta aacgactgag gtaacgtaga tgaaattgtt
       61 ttaagggttt cttgaaagcc taccgtatct cgtttaacga aataatagcg taataattga
      121 caaaaatgat acgcagttcg caattcttcg ttgtagctta acagctcatt aacgatttct
      181 gtttgactaa ttggtcgttt aaacagtcga tgataatgcc gtttgagtgc ctcccatgtc
      241 gtggaatctt tgagtaagag tttccaatat cgcttgagcc gacggtactt cttctgattt
      301 tcagagtgtg aggttcgaaa acgattcatg atctggacac gtaattgatt gaagctgcga
      361 ttgatgtgtt ggacaatatg aaagcggtca gttacgatct ccgcatttgg aaagaccgtt
      421 ttaagcaact gacaatagct ggcattcatg tccatcacta ggtacttgac ctttaaacgg
      481 gcctttctag gaaagcgcag gaagtattga gttagtttgt aaagtctgcg atcttcaagg
      541 gtcgtaaata gctgattggt tgtcccatca acacaaataa aactcatgga accagaagtg
      601 gcaacattgt gtacttttct ttgcaatctt gtgtacaaaa ctattgcaaa acacagcgca
      661 taagaatcct tacaaaacag tagatgaagc aacccaatta gatcttgtta tagttgttaa
      721 tcagctctta acgggttacg attcaaaatg ggtcaacacc ctatacttag ataagtcact
      781 tgaatatcag aacataattc aggctttttc acgcacaaat cgtcttaatg gtcctgaaaa
      841 accgttcgga accattcgtt attatcgtaa agcacatacg atggaacaga acattgaaga
      901 ggctattgag ttatactcag gcaaacaagc aaaagggtta tttgttgaaa aattatataa
      961 taacttagaa aagttgaacg atatattcga agaaattaag tccgtattta atatttctgg
     1021 catagaaaac ttcagtcatt taccggaggt tccaggggaa attaagcaat ttgtaaatct
     1081 ttataatcaa ctaatccatt gttatgaatc agcgatgata cagggattca catgggcaaa
     1141 atcgacttat gaaatccagg attatgaacc tataacagta gtaatcacag aatatgaatt
     1201 taatatcttg gcacaacgtt acagcgagat agagagaacc tagagacgga aatgatagta
     1261 tagcgtatga cattgattac caattacctg aaggtagtcg tagtcgtatt aattatgagt
     1321 atttaaacac aaacttcaaa aaatacatga atataaaaga agaacgtgat tcgaatttaa
     1381 ttcaatcatt gttaaacgac ttacatcgca catttgcgca attaccagtg gagttacagc
     1441 catatgctga gatgattcta aatgatgtaa ataatgggga attagttatc aaagaaggat
     1501 gggaatttac tgattacctc aatgaatttt agtggattca accaatatta atgaggcatt
     1561 attacgtgag atgttggatt tacgcttaac cgaggtaaac attaatgaat atagtcgatt
     1621 tgataaatta aaatcaagtg ttaacgtagg tcatttcagt ggatatatcg agaaaaattt
     1681 aggtaaaatg gtaataccaa tcaaggtaaa tatgctaatt gacagattat tgcgtgcatt
     1741 tttattagaa gatgtattcg atgttacaga gtacataaag aattacttta actagagtac
     1801 acctacatct tatagtacat aaaaaaattc atctttttta gtt
//
LOCUS       DARBDN010000198         1796 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000198 DARBDN010000000
VERSION     DARBDN010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.204"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            29..1381
                     /gene="brnQ"
                     /locus_tag="SCH06_002879"
     CDS             29..1381
                     /gene="brnQ"
                     /locus_tag="SCH06_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEG1079388.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT          503 a          309 c          353 g          631 t
ORIGIN      
        1 ttttaaaaaa accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct
       61 ttttataggc tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt
      121 tcatttgggt caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac
      181 cggtatcggt cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt
      241 atatgaatta gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta
      301 cttagttatc ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg
      361 tttagcacca tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt
      421 attttttgtg ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg
      481 aaagttcctg aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt
      541 gaatccacta ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt
      601 tttcacaggg tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg
      661 gatcatcatt gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa
      721 agacacgatc aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct
      781 cgcttattta ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac
      841 gctggctcag attgctgatc attatttagg tacttatggc agtatcttat tagcatttat
      901 cgttatatta gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt
      961 cacagatttg tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc
     1021 ttgtttagcg gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat
     1081 gttcatctat ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa
     1141 gcagcgtacg gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga
     1201 tgggttgaac gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata
     1261 tgttgcggaa agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt
     1321 tatcggtttt gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg
     1381 ataaaagagg ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat
     1441 ggcttctcac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     1501 tttattgaga ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa
     1561 atggcttctc acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac
     1621 cgtttattga gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct
     1681 ccatatactt tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt
     1741 tcttttataa tatagatttt agacatatat atgatataaa aatagttttc gcaaaa
//
LOCUS       DARBDN010000199         1793 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000199 DARBDN010000000
VERSION     DARBDN010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.205"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            25..657
                     /locus_tag="SCH06_002880"
     CDS             25..657
                     /locus_tag="SCH06_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1079389.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            862..1089
                     /locus_tag="SCH06_002881"
     CDS             862..1089
                     /locus_tag="SCH06_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEG1079390.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            1158..1424
                     /locus_tag="SCH06_002882"
     CDS             1158..1424
                     /locus_tag="SCH06_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEG1079391.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            1414..1683
                     /locus_tag="SCH06_002883"
     CDS             1414..1683
                     /locus_tag="SCH06_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEG1079392.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT          635 a          279 c          376 g          503 t
ORIGIN      
        1 gttcaaggat aggagtgaat tcgaatgaca atgggagtaa tttttgatat ggatggggta
       61 ctcatagata gcgagacatt ttattttgag agaagaatga acttctttca agaactggag
      121 atagatccag gatcaaacca gattgatgat tatgtgggga aaacagaagc tgcaatatgg
      181 gaaacattag ttcctgagga caaatcatta agagaggaac tttatccgaa atatgtagat
      241 tatcgaaaaa cgcatccaat tgatttcgct aaagctttac gaaaagaagt gaaaccgtta
      301 cttgacttcc tcaagaagcg ggatatacca ttggcactgg catcttcttc tccagctgtc
      361 gagatagaga gtatgctcat tcaatgtgaa cttactgaat atttttcctt tgttataagt
      421 ggtgagtcat taaaacaaag caaaccacat cccgaaatat atttaaaagc gaaacagcaa
      481 ttagactgtg acttctttat tgcagtagag gattcaacga ttggtattaa atcagcaaag
      541 gcagcaaata tctatacggc ggcactaaaa caaccaatgc aaatcgatca gagtgaagca
      601 gacatacaaa ttgaaagtct acaagaactg gaacaaattg ttttagaaaa aggttagtga
      661 attaatggaa ataaggctat atatctgtgc tagctatttt gactaaccaa aaaaacttgc
      721 tataattcag gtgtagtaaa aggtgctggt aacacctttt acgaaaatgc ttcggcagtg
      781 ataatgggat tggcttttta agttttttat tttgttcgca atccctaagg tcatgtgaat
      841 gatcctaggg attgctagaa tattttgcaa cagaaccaaa atacgaatag ttatcaagca
      901 gccatattga ctgcggtcaa tttaggaggg gatactgata ctactgctgc cgtaactggt
      961 gctcttgcgg gtattcttta cgggggtgaa gtgatccctg aaaattggag aaaatcgctt
     1021 caaaatgacc agcttcttaa aacgatcagt cagagatttt gcgataccgt gctatctcaa
     1081 agaatttgaa taatggatat gatgcaaatc ttgtttgtac taacgttgta ttgacaaaaa
     1141 ggattttatt tagtacaatg ttagtacaaa tgatgaacgg aggtagaatc atgtctcaat
     1201 caaccattac atttaggatt cccgacgatg aaaaagaact ggtattagaa tatgcaaaag
     1261 cacacaattc ttcattgacc gaactttatc gaaatgctgt actggataaa atcgaagatg
     1321 aaatcgatct acggacttta cggagtgcaa ttgaagtttc caaagagaaa aaagagagtg
     1381 gtatttctca agaggaaatg gagaaactgc taaatgaatt ataaagtcat ctacatgccg
     1441 caagcccaga agcaattaaa aaaaatggac agaaaccaag ctaaaataat tgtcgcctgg
     1501 atcagaaaga atttagaaaa cacgactgac ccgcgtcagc acggaaaagg tttgactgga
     1561 aataagagtg gggaatggcg ctatcgaatt ggaaactatc gaatattggc taatatttgt
     1621 gattctgaaa ttgaaatcca gatattctca attggacata gaagtacaat atataaaaga
     1681 taaccgtttt tggaacgaag tagagtttcg aaagtcaatg tataatcttt tgaattttgc
     1741 ataataccac aggtagaaac tacccgatac tatcggttgg tttctgcttt ttt
//
LOCUS       DARBDN010000200         1708 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000200 DARBDN010000000
VERSION     DARBDN010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.206"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(27..1508)
                     /locus_tag="SCH06_002884"
     CDS             complement(27..1508)
                     /locus_tag="SCH06_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079393.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT          529 a          232 c          297 g          650 t
ORIGIN      
        1 aataagagga tgtgacaaga attttgtcac atcctctttg ttttgttctc ataacctttt
       61 ttcatataca gttcatgaac cgcttttatt aacttgccaa ataacactgt attgtgcgtt
      121 gtatccagat agaaagtctc cgtttcatct gaaattttct catgctgatc tgtaatgatc
      181 aaatcagcat gttctgaata tgcggtaatt ttaacagcat ctttgcgaaa taactgctgc
      241 aaatggcttt gaagatgata atttcctgta aactgtttgg ttatctgcaa atggatgagt
      301 aactgctctt tcgtttctgt ttgtagtaag tgttggatca attgactaag gtattgactg
      361 atttggtttc tttccccatt ttttgaaaaa attgtatcga ttttttctct taatttcttt
      421 tcctgtataa aagaactaga atgattggac gtggcttctg gaaagcaaag tgtagaaaaa
      481 ctactgctgg attcacccaa cagttcgaaa aaaacaactg ccaacacaag aaaataaaaa
      541 taaattggta ttttattttc taaatggttg agaggaaact gttgagttaa gtaagtcatc
      601 aattgaccga cttgtcgaca aataaggttt ttgcttgtgg aaaataaaaa accaatctcc
      661 tgtttttgtc gaaaagagat ttgatttgga aaaaaacaat agaaaaaata attaaagtag
      721 gctctctctg tttctgtctc ttcacaaggg cgactcactg aaaaagaagt aaagtattct
      781 gaataatcat gtgtatgctg caataagtcc atcaattcag tgatttcaga agaagttttt
      841 ggaaaatatg cctgttgttt gtttcgtaat atgaataaag ttaacagcaa gtagatattt
      901 ttttcttgtt ttgaaatttt ttctatttgc tcatctgtac tgttcatttt tagtgcattt
      961 aattcaagtg aggaaaatgg ccaatcgtta cctccaaatg tatctgaaag aaaaaagtaa
     1021 agatagagac ggatagataa ctcatttcct tcaagagtac agcaattttt tacagatagg
     1081 atccgtaaat ggaatttttt taaggaatga ttgagctgtt ttgtcagttt ttcgagatag
     1141 gagggcgata tataaagttg ttcaagtaaa tatttttttg gtacagcagt ttgtggataa
     1201 ttgattagta acatcaaata gttaaaacga ttggattctt ttaggtagca taattttaac
     1261 ttagaaaaaa cagctaactt tttagtttga tcggtttctt tggtttggat ctctccttta
     1321 tgattagaat aaataaattc atcaatcaat aaaaattgct tgagtgatac atttattttt
     1381 cggatcagtt ctttgattgt ccgttttgga atatgtaagt cattggataa ttcttgtaaa
     1441 gaacaattat ttttttgaat gaccatttgt agaacaagta actctttttt tcttgcttca
     1501 attagcataa atacctcctt tttattctgt ttttgtatat agttagacaa aaactgtgag
     1561 tggaaagtca tttcagtctg tgttattctc acagagtgtc gccttctttt ttatataacg
     1621 ttatttaatt tttttgttac cttgtttatt ctattgttta tttcctaggg tattttgtca
     1681 agatattctt gtttttaagg cggaaaaa
//
LOCUS       DARBDN010000201         1702 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000201 DARBDN010000000
VERSION     DARBDN010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.207"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(139..516)
                     /locus_tag="SCH06_002885"
     CDS             complement(139..516)
                     /locus_tag="SCH06_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079394.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(816..1697)
                     /gene="galU"
                     /locus_tag="SCH06_002886"
     CDS             complement(816..1697)
                     /gene="galU"
                     /locus_tag="SCH06_002886"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEG1079395.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          477 a          379 c          248 g          598 t
ORIGIN      
        1 atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga aaaaagcttt
       61 tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt atcttttttt
      121 gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt cgagagaatc
      181 tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact ttcttttcat
      241 atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata cgcaagcttc
      301 ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg ctgcatacca
      361 gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa atagactaat
      421 aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact tgagtatatc
      481 aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc tttttttata
      541 attaaaaaat tcgccttttt attctactat gaatcttctg gcttggcttt catttctctt
      601 atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca taatattttc
      661 tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa ctgatctaga
      721 gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt taataacaaa
      781 tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct tagcttttta
      841 ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg aagtccatat
      901 tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt tcctttaaac
      961 tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt tagctgtatc
     1021 tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg agtcagtaga
     1081 taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt ttctacaaac
     1141 ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat tccgtattta
     1201 gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt ttcttcataa
     1261 tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc ccccagcatg
     1321 acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc ccccagtcct
     1381 cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc aactaaagcg
     1441 agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt tgcatcaaag
     1501 tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc gattcccgaa
     1561 tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg aagcatttct
     1621 tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc aggaatgact
     1681 gcttttttga ccttcacttg ct
//
LOCUS       DARBDN010000202         1664 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000202 DARBDN010000000
VERSION     DARBDN010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.208"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(45..1511)
                     /locus_tag="SCH06_002887"
     CDS             complement(45..1511)
                     /locus_tag="SCH06_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HEG1079396.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          562 a          337 c          300 g          465 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatt
//
LOCUS       DARBDN010000203         1656 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000203 DARBDN010000000
VERSION     DARBDN010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.209"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            16..1044
                     /locus_tag="SCH06_002888"
     CDS             16..1044
                     /locus_tag="SCH06_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEG1079397.1"
                     /translation="MNSKKLQMGEIVRGPSQISIDVTYKCNFRCKHCYNASGGDNCFM
                     DNELTDDELLELTKDICNLKPYNICFCGGETLLRKKIVLSCATLLKEAGIPNIAIVTN
                     GSLVTQDVAKELFKAGINRFQVSLDGKNASSHEALRLYPNSFEKAINAIKLFRELSEE
                     VDVAFCPTSFNYNQLREVYQLVNTLKVKSLRIQPFMLSGRGMQNREIVPTVSQYRKLV
                     SDINYIKRNEDYTKIDWGDPIDHIIRHRTLLKDFSNFVSIRSDGGLMASPYLPIQVGN
                     IKCHSLSKYWRAGLYKVFSLDLVQDIATQVSSIQDMSKELKKGHIKWLNEDIEIDILD
                     EYKHDILI"
     gene            1100..1318
                     /locus_tag="SCH06_002889"
     CDS             1100..1318
                     /locus_tag="SCH06_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079398.1"
                     /translation="MISEPQMNNMYESPTIMGAGEAAPRACSAIMVCVLLASAGVGIQ
                     AGAVYTYAVVATVAVAAAAVWKTVGLVG"
     gene            1389..>1656
                     /locus_tag="SCH06_002890"
     CDS             1389..>1656
                     /locus_tag="SCH06_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079399.1"
                     /translation="MKYNNLKPKLLNENIEYIREENYGYLTIVPKNGTESKDNVFNPT
                     VRYILANCTGKNSVKKIANGLKKKFPSLEYEKFYQDVVGTIKFFK"
BASE COUNT          623 a          194 c          315 g          524 t
ORIGIN      
        1 aggagtatga taataatgaa tagcaaaaaa cttcagatgg gtgaaattgt tagaggtcct
       61 agtcaaatat ctattgatgt tacatataaa tgtaatttta gatgtaaaca ttgttacaat
      121 gcgagtggtg gagacaattg ttttatggat aatgagttga ctgatgatga actgttagaa
      181 cttacaaaag atatatgtaa tttaaagcca tataatattt gtttctgtgg aggagaaact
      241 ttactgagaa aaaaaatagt tttatcttgt gccactttat taaaagaggc aggtattcct
      301 aatattgcta ttgttactaa tggatcatta gtaactcagg atgttgcaaa agaattattc
      361 aaagcaggta ttaatcgatt tcaagtaagt ttagatggaa aaaatgctag tagccatgaa
      421 gcacttagat tatatccaaa cagttttgaa aaggcaatta atgctatcaa attatttaga
      481 gaattgtccg aagaagtgga tgttgctttt tgtcctacta gttttaatta caatcaatta
      541 cgagaagtat atcaactagt aaatactctt aaagtgaagt ctttaagaat tcaaccattt
      601 atgcttagtg gtaggggaat gcaaaatagg gaaatagtgc caactgtttc tcaatataga
      661 aaactagttt ctgatattaa ctatattaaa agaaatgaag attataccaa gatagattgg
      721 ggagatccaa ttgatcatat catccgacac agaactttat tgaaagattt ttcgaatttt
      781 gtttctatta ggtcagacgg aggattaatg gcatcacctt acttgccaat tcaagttgga
      841 aatattaaat gtcacagtct ttctaaatat tggcgagcag gactttataa agttttttct
      901 ttagatttag ttcaagatat agctactcaa gtttcttcaa tacaagatat gagtaaagaa
      961 ttaaaaaaag gacatattaa atggcttaat gaagatatag aaattgatat tctcgatgaa
     1021 tacaaacatg atattttaat ttaggtttat cattggaaag tttagataaa caaagtactt
     1081 ttagaaagga gggaaaaaaa tgatttctga acctcaaatg aataatatgt atgaaagccc
     1141 aactataatg ggagctggtg aagctgcgcc aagagcttgt tcagcaatta tggtgtgtgt
     1201 gttattagca tctgcaggag taggtatcca agcaggagcg gtgtatactt atgctgtagt
     1261 tgctacagta gctgtagctg cagccgcagt ttggaaaaca gtaggattag ttggttagga
     1321 attaatagga gactaactgt ctcctattga ttccaatgat taagctaagg aggaatttta
     1381 agaaaataat gaaatacaat aatttaaaac cgaaattact taatgagaac atagaatata
     1441 taagagaaga aaattatgga tatttaacca tagttcccaa aaatggaact gaatcgaaag
     1501 ataacgtttt caatccaaca gtaagatata tattggctaa ctgtactgga aaaaacagtg
     1561 taaaaaaaat agcgaatggt ttaaaaaaga agtttcctag tttagaatat gaaaaattct
     1621 atcaagatgt tgtaggaact attaaatttt tcaaac
//
LOCUS       DARBDN010000204         1647 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000204 DARBDN010000000
VERSION     DARBDN010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.210"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(20..91)
                     /locus_tag="SCH06_002891"
     tRNA            complement(20..91)
                     /locus_tag="SCH06_002891"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="SCH06_002892"
     tRNA            complement(113..200)
                     /locus_tag="SCH06_002892"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="SCH06_002893"
     tRNA            complement(225..298)
                     /locus_tag="SCH06_002893"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="SCH06_002894"
     tRNA            complement(312..382)
                     /locus_tag="SCH06_002894"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="SCH06_002895"
     tRNA            complement(384..459)
                     /locus_tag="SCH06_002895"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
     gene            complement(478..551)
                     /locus_tag="SCH06_002896"
     tRNA            complement(478..551)
                     /locus_tag="SCH06_002896"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(515..517),aa:Met,seq:cat)
     gene            complement(564..653)
                     /locus_tag="SCH06_002897"
     tRNA            complement(564..653)
                     /locus_tag="SCH06_002897"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(615..617),aa:Ser,seq:tga)
     gene            complement(677..750)
                     /locus_tag="SCH06_002898"
     tRNA            complement(677..750)
                     /locus_tag="SCH06_002898"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(714..716),aa:Ile,seq:cat)
     gene            complement(764..837)
                     /locus_tag="SCH06_002899"
     tRNA            complement(764..837)
                     /locus_tag="SCH06_002899"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(801..803),aa:Met,seq:cat)
     gene            complement(865..937)
                     /locus_tag="SCH06_002900"
     tRNA            complement(865..937)
                     /locus_tag="SCH06_002900"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(902..904),aa:Ala,seq:tgc)
     gene            complement(957..1030)
                     /locus_tag="SCH06_002901"
     tRNA            complement(957..1030)
                     /locus_tag="SCH06_002901"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(994..996),aa:Pro,seq:tgg)
     gene            complement(1040..1113)
                     /locus_tag="SCH06_002902"
     tRNA            complement(1040..1113)
                     /locus_tag="SCH06_002902"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1077..1079),aa:Arg,seq:acg)
     gene            complement(1124..1209)
                     /locus_tag="SCH06_002903"
     tRNA            complement(1124..1209)
                     /locus_tag="SCH06_002903"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1173..1175),aa:Leu,seq:taa)
     gene            complement(1226..1297)
                     /locus_tag="SCH06_002904"
     tRNA            complement(1226..1297)
                     /locus_tag="SCH06_002904"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1263..1265),aa:Gly,seq:gcc)
     gene            complement(1309..1381)
                     /locus_tag="SCH06_002905"
     tRNA            complement(1309..1381)
                     /locus_tag="SCH06_002905"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1346..1348),aa:Thr,seq:tgt)
     gene            complement(1399..1480)
                     /locus_tag="SCH06_002906"
     tRNA            complement(1399..1480)
                     /locus_tag="SCH06_002906"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1444..1446),aa:Leu,seq:tag)
     gene            complement(1488..1560)
                     /locus_tag="SCH06_002907"
     tRNA            complement(1488..1560)
                     /locus_tag="SCH06_002907"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1525..1527),aa:Lys,seq:ttt)
     gene            complement(1564..1636)
                     /locus_tag="SCH06_002908"
     tRNA            complement(1564..1636)
                     /locus_tag="SCH06_002908"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1601..1603),aa:Val,seq:tac)
BASE COUNT          438 a          460 c          391 g          358 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca gtgtttttag tttttaattg
      481 cgggagcagg atttgaacct acgaccttcg ggttatgagc ccgacgagct accagactgc
      541 tccatcccgc gataatatga aaaaggagga taagggattc gaacccttgc acggttttac
      601 ccgcctgacg gttttcaaga ccgttccctt cagccggact tgggtaatcc tccatatgaa
      661 acttacaacg ccacaatgga ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
      721 gtctgctcta accaactgag ctaaaggtcc aggctcttaa aaatcgcggc ggaggggatc
      781 gaacccccga cctcccgggt atgaaccgga cgctctagcc agctgagcta caccgcgaaa
      841 aagatattca ttatttaaat gaaatggagc ctagcgggat cgaaccgctg acctcctgcg
      901 tgcaaagcag gcgctctccc agctgagcta aggccccgtg tttaaattta taattatcgg
      961 gaagacagga ttcgaacctg cgaccccttg gtcccaaacc aagtgctcta ccaagctgag
     1021 ctacttcccg tttaattaac gcgcccaaga ggagtcgaac ccctaacctt ttgatccgta
     1081 gtcaaacact ctatccagtt gagctatggg cgcatatttg aaatgccgag gaccggaatc
     1141 gaaccggtac ggtgatcact caccgcagga ttttaagtcc tgtgcgtctg ccagttccgc
     1201 caccccggcg cgattgcttt ggcaaagcgg aaaacggggt tcgaacccgc gacccccacc
     1261 ttggcaaggt ggtgctctac cactgagcta tttccgcgtg tttaaagatg ccggctaaag
     1321 gacttgaacc ctcgaccctc tgattacaaa tcagatgctc taccaactga gctaagccgg
     1381 catgtaaaac ttaaattatg cgggtgaagg gacttgaacc cccacgccgt aaggcgctag
     1441 atcctaaatc tagtgcgtct gccaattccg ccacacccgc aaaaatatga gccgtacagg
     1501 gctcgaacct gtgaccctct gattaaaagt cagatgctct accaactgag ctaacggctc
     1561 atatggaggt taacgggatc gaaccgctga ccctctgctt gtaaggcaga tgctctccca
     1621 gctgagctaa acctccatgg ataactt
//
LOCUS       DARBDN010000205         1610 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000205 DARBDN010000000
VERSION     DARBDN010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.211"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            191..445
                     /locus_tag="SCH06_002909"
     CDS             191..445
                     /locus_tag="SCH06_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEG1079400.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="SCH06_002910"
     CDS             446..763
                     /locus_tag="SCH06_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEG1079401.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..>1610
                     /locus_tag="SCH06_002911"
     CDS             1322..>1610
                     /locus_tag="SCH06_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079402.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSR"
BASE COUNT          577 a          225 c          303 g          505 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaagacaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga aacgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa
//
LOCUS       DARBDN010000206         1586 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000206 DARBDN010000000
VERSION     DARBDN010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.212"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            4..963
                     /locus_tag="SCH06_002912"
     CDS             4..963
                     /locus_tag="SCH06_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HEG1079403.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLSDGTNHSHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1152..1225
                     /locus_tag="SCH06_002913"
     tRNA            1152..1225
                     /locus_tag="SCH06_002913"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Ile,seq:cat)
BASE COUNT          530 a          283 c          310 g          463 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttaccaa gtcggacaac ctggttatgt acagtacggt
      241 gctggttcat atgctaatgc caatagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaactt ttgaaaaaaa ctataaagca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac attagacacg ccttataacc aaccaggaat caaatcacat
      421 ttatgggtaa ctcaaaacat ttggggcgat cacactgatc cgtatggata cttatcagaa
      481 atgggtgtaa gtaaggaaaa actggcttac gatttagctc atggatttac agacgaaaac
      541 ccaacgactt ctgagaacaa gcctgtcatt gatccaaccc gagcaggtgc agcaaatcca
      601 actttatcag atggaacgaa ccattctcac attgatcagt ttggagaaat cgaaaatgcg
      661 aacttacacg tcgctggatg gcacatcgct aactataagt acgagtatat tttcattatg
      721 gactacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagaccggat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc cataatagtc acactccaag
     1081 ctatgcgata acaggtttgt tgccacacat tctactggtt gattgtttat ggctttatgt
     1141 ggcaacaacc agtaccctta gctcagttgg tcagagcaga cggctcataa ccgtccggtc
     1201 gtaggttcga gtcctacagg gtacattaac gtagccattt gaatcgttct gtgttagaat
     1261 tttttgaaga gtattataca agctaaagct tttcttcatt gccactcaaa tgagtggctt
     1321 ttttatgtat ccttttatgg attaatgaaa ggatgtttca catagttata tttctgtata
     1381 tttgaaaagt tttactttga tttttaaata gaaagacatt tgggttatat tgtgagataa
     1441 taataaagaa gagtttaaag cgttccccaa aaaccactgc cccataagtg tgttacgctt
     1501 taaactcttt tatatttgaa gccattaaaa agcataccat atttttgaaa aaaagtgaga
     1561 aaaaaggctt ataattggag tggtag
//
LOCUS       DARBDN010000207         1568 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000207 DARBDN010000000
VERSION     DARBDN010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.213"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            44..1156
                     /locus_tag="SCH06_002914"
     CDS             44..1156
                     /locus_tag="SCH06_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEG1079404.1"
                     /translation="MLFSLSAFSTGTILGWQFYNNEHSQIVAHAQSAQKKLILTTNEQ
                     QLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKLTQQPNDPSLYYQIGSVQKA
                     LTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDLLYMRSGLHRTASPTIPMTD
                     EEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQPYEKLLTDDIIEPLGLQHT
                     KFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNELGTGNISMSVYDLNTLFTQV
                     LSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQGNIDSFDTSAIFSKDSQDAI
                     IMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT          555 a          277 c          249 g          487 t
ORIGIN      
        1 acatgctaaa aaaagaaaat attcattttt aatgatcgtt gtcgtgttgt ttagccttag
       61 tgcgttctct acaggaacta ttcttggatg gcaattttac aataatgaac actctcagat
      121 agttgcccat gctcaatcag ctcaaaaaaa gttgatactg actaccaatg aacaacagct
      181 cgttgaaaaa atcgatcaac tattaagaaa aaatgattat attggctcaa tttacgtaaa
      241 gaaaaataat cgcatcatca tggaaaaagg ctatggctat gcgaataaac tcacgcaaca
      301 accaaatgat ccttctcttt attatcagat tggttcggtt caaaaagcat tgactactct
      361 tttgatttta aaacaagtcg agcgtgggca cctttcttta gatactaagc tggctcaatt
      421 ctatccacaa attgctggca gccagcaaat tactatccgt gacttgctgt atatgcgctc
      481 aggcttgcac cgaactgctt ctccaaccat accgatgact gatgaagaag tcgttcaatt
      541 tgcgattcag cacttaaaat ttacagatta tcagacctct cattatgatt cattgaactt
      601 taccatattg actggaattt tgatcaaatt aacaaatcaa ccgtatgaaa aattattgac
      661 cgatgatatc atcgaacctt taggattaca gcatacaaaa ttttatgacc aagtcaaaaa
      721 ttcatccaat catgcactat cctatcaaat gtctaaagag gatgattact ttaaaccact
      781 gacagaatct gaaacagaga tccataacga attagggact ggtaatatca gtatgtccgt
      841 ctatgattta aatacgctgt ttacacaagt tttatctgga aaactagttt ccaaagactt
      901 actcttctca ttatggcgtg aaaatgcgaa tggacatcca tatagtggtg gggtatatag
      961 cggagataat tatatcctgt cgcaaggaaa tatcgactct tttgatacat ctgctatatt
     1021 tagcaaagat tcacaggatg ctatcatcat ggaaagcaat ataaaagctg acaaaactat
     1081 caaactgcct actgctgatc taagaaacca aatctatgac ctgatggaag gaactactaa
     1141 gttggcaaat agctgatatg atgaaaagat agcaaatact acttctttga atagcatttg
     1201 cttaaaaaaa gtactcgact aaacgtagga aagagtgtgg gacaaatcta aaaatcaatt
     1261 tttgctacag actttaattc caaataaaca gaacagaaag aggtgttctt ctttctgttc
     1321 tgtccaaatt attctaagat ttctctttac caacattatt tgacaaaggg cctattaaat
     1381 ctaaaatagt atctttagat tgctaaaata tgtgctagca aatcattcat ggcttgttct
     1441 tatttttaat tttatgcaat aaaaaagaag aacaattagc gtgattatag aaataaataa
     1501 tgagatttta gaaaaaaatg tgtatgaata cctgattgtt actttattta ttccactttc
     1561 acttttta
//
LOCUS       DARBDN010000208         1509 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000208 DARBDN010000000
VERSION     DARBDN010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.214"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            101..868
                     /locus_tag="SCH06_002915"
     CDS             101..868
                     /locus_tag="SCH06_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEG1079405.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            1060..1458
                     /locus_tag="SCH06_002916"
     CDS             1060..1458
                     /locus_tag="SCH06_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEG1079406.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT          561 a          189 c          282 g          477 t
ORIGIN      
        1 aatactgtta aatatctcga aaaatcaatt acgagttatt tgccttatgt gaacctttat
       61 gattaacaac tgaaaaaatg cgtgaaggaa ggaaaaactt ttgaaaaaag atgaactgac
      121 aaagtacaat gaggagttct tagcaacaat tgacatgaaa atggatttaa agtcgtatga
      181 actttatcaa ttgctgttca gttatatctc acccacaaag ctaaagaaaa caggcgtagt
      241 agatttacct gttaaagcga ttattaatta catggatgtt gatcaaaatc ttgaaacgga
      301 actaaaaacc atagttaaca ctttgcaaag acaagcagtt tatgaaattt cgaatctaga
      361 caaaaaatat aagacgtata ctactgtatc tgctattgat cggattcatt gggatttaga
      421 agagcatagt gtatctttca gtttttcaga agatgtaatt cccttaattg tctcaatcaa
      481 aaagaagtat ccgttctttg tttttgaaga cttagcatct tttcaaaaaa aatatagcat
      541 cgtgttatac aaatatttgg cgatgtatta taaaaaatat cttatcgcca aaaataaagg
      601 agattttgag aaagctgaaa tatataagaa tcccctgatt gaaatagtta aaattcgtga
      661 gattacgaaa acagaaaatg agtataaaac aatatcgaat tttgatagac gtgttttaag
      721 ggaatcagtt gaggaaatta atgaaaaatc aatgctgaat attgattttg ctaaagttag
      781 aaaaggcaga aattacaatt ttgctgtcca gtttaatatt tctagtgagt ttgatgaaaa
      841 aacttataga gaaaaaaaat taggttaatg caaaatatat cttactcgtt tgaagatgct
      901 tcagacgtat gctaagatat atagtgcctt gggagcaagg tattaatctc ctttagaggt
      961 taattagctt gtgatcgcct atcaattttt ttggtaggcg attctttttt ttgaaacaaa
     1021 aaagcaaaaa ttatttttta attagagagg tgcaatgcga tgaaatactt tttttgtgca
     1081 gtattcgaat ggaaaggaaa tgaatatgca gttaaattcc cagattttcc agacttatat
     1141 acacatggtg aaactttaga agatgctttt gagatggcgc aagaagtatt ggaaggatac
     1201 ttggtgcttt tagagttgca agaaaaagaa attccatcgc ctacgcctgt tcaagagtta
     1261 aatgcaagaa tcaagcgatc tgagaatgtt aatttatttg tcgtaaaagc taatacgaaa
     1321 gttgctaaag ctcgaaacaa gcaaaattat gatcgaaaat cagtgactgt ggaacactat
     1381 ttaaatgttt tagcggctga agagaatatt aatctgtcga aagctttgaa tgatttgttg
     1441 agagaaaagt tgatttgatg tctctcagat gatcatatta agcaaaaaca gcttgtttta
     1501 ggacgtatg
//
LOCUS       DARBDN010000209         1479 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000209 DARBDN010000000
VERSION     DARBDN010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.216"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            2..400
                     /locus_tag="SCH06_002917"
     CDS             2..400
                     /locus_tag="SCH06_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEG1079407.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="SCH06_002918"
     CDS             384..1079
                     /locus_tag="SCH06_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEG1079408.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
BASE COUNT          554 a          214 c          301 g          410 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattactt atttctcatt taaacgatgt
     1201 attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt gaataaattt
     1261 cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct agtataacag
     1321 aataagagga acaagtccag aagggatatt tttagtcttt tttaaaataa cttttcagtc
     1381 gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa atagggaagc
     1441 atgaaagaat ctacttaatg gcgcattgat tcatgtgat
//
LOCUS       DARBDN010000210         1454 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000210 DARBDN010000000
VERSION     DARBDN010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.217"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..625)
                     /locus_tag="SCH06_002919"
     CDS             complement(<1..625)
                     /locus_tag="SCH06_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HEG1079409.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFD"
     gene            complement(784..1050)
                     /locus_tag="SCH06_002920"
     CDS             complement(784..1050)
                     /locus_tag="SCH06_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1079410.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(1040..1396)
                     /locus_tag="SCH06_002921"
     CDS             complement(1040..1396)
                     /locus_tag="SCH06_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEG1079411.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          406 a          279 c          181 g          588 t
ORIGIN      
        1 gatcaaaaat atctaagttg tcatcaaaat ctttatcagt tccggtaact tttttgttaa
       61 ttactgaagg tgtcttgtaa gaaatagaat ctaaatcaaa gcgttttgat tctaaattat
      121 tttgtgcttt ctcaattaaa taattcactt tttttgtgag aaaccttctg atattgtctt
      181 tgctatatgt tccataaaaa cccttatctt ctaaagagtc cctgtacttc ttaacttcta
      241 tatactcttc agccaaaact tgtggaactg gttcatctaa gaaaaaaacc cctacctcgc
      301 ctttgctatt tttataaaag taatcaattt ctgctatagt tcccgatcta taattatcaa
      361 ctggagaacc caacttatgg ccaaaaatcg ctaataatat atcactattt tctacaattt
      421 gtttattaat aacactttgc ccagagctat tatttatata agtaggaatc gcattcgttt
      481 cccatcgaat tggcatcaaa attacttttg tattatctgt attttctata ttccatctat
      541 atatggtttc ttctacttca ttcctctttg ctgctatatc acctggtgat gctataaata
      601 cttttattag atttatggtt ttcatttatt gtacctttct ctttatgtct ctttaaagta
      661 atttttgtat aaaatttatt gacttttaca ctataggaca acttttatct atttagtaca
      721 aaaaggccca ctaaactaat tgattagtta ggagcctatt acaggtatat tttcaactcg
      781 cttttaagca aattctacta ccagcttttt gcctaatgcc ctagcgatat catcaagttt
      841 atcgaaagat acgttatccc ctctctcaat tcgagcaata gtagattgag ttgtatgtgc
      901 tttttgtgca agctccgctt gagttaggcc tgcttcctcc cgtgcatgat aaagagcaac
      961 cgcagtttcg agttttcttc cttcacggtc atatgcttct gcaaaatctt tgtctttttg
     1021 cttttcttca atcaattttt taatcatcat ttgtgaacca ctcctctcta agttcttttg
     1081 catgtttaag ttcacttatt ggtgttttct ccgttttttt agtaaatcca tgggtaatga
     1141 cataccttcc attgaccaca tggaaataga tagctctttg gatgtttgat cctaccttac
     1201 ttcttaattc gtacaaatta gtgtctaatt ttttcaccca tttcaaccgt tgagctacta
     1261 gcatcccatt cttttctgtt tcttctattg tacgtaaaag cttcgcacta tctttttttg
     1321 gtaatgtttc caaccattct aaaaattcat catgaccatt aggtctttta aatgtttcaa
     1381 aagatatttt ttccataccc aattatatca tatattgatt ttatattata gtatataaca
     1441 taaaaattcg aatt
//
LOCUS       DARBDN010000211         1440 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000211 DARBDN010000000
VERSION     DARBDN010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.218"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            105..1406
                     /locus_tag="SCH06_002922"
     CDS             105..1406
                     /locus_tag="SCH06_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEG1079412.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          474 a          288 c          264 g          414 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DARBDN010000212         1424 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000212 DARBDN010000000
VERSION     DARBDN010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.219"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(150..1337)
                     /locus_tag="SCH06_002923"
     CDS             complement(150..1337)
                     /locus_tag="SCH06_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HEG1079413.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DARBDN010000213         1409 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000213 DARBDN010000000
VERSION     DARBDN010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.220"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..294
                     /locus_tag="SCH06_002924"
     CDS             <1..294
                     /locus_tag="SCH06_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEG1079414.1"
                     /translation="ECQIRAKRMAIDYCRLYVGLVDDANLGIKEKRKYIKKFIEDEGL
                     IQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSRIRKIIKNMTRKKLFIIL"
     gene            912..>1409
                     /locus_tag="SCH06_002925"
     CDS             912..>1409
                     /locus_tag="SCH06_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079415.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTANFA"
BASE COUNT          530 a          130 c          233 g          516 t
ORIGIN      
        1 gaatgtcaaa tcagagcaaa acgtatggca attgattatt gtaggcttta tgtgggctta
       61 gttgatgatg caaatttggg aattaaagag aaaagaaagt atataaaaaa atttattgaa
      121 gatgagggat taattcaatg ttggaaggga tatcctacaa atacgctacc atttcaacaa
      181 aaattttttc ataaaatgct tgaatgtaag tgttatacaa tattgttgtt gttaagtaga
      241 attagaaaga taattaaaaa tatgaccaga aaaaaattgt ttataatatt ataaactaaa
      301 agtatatcaa ataatagaaa ttaacaagtt acaaaaaaat attataaaga ataatatttt
      361 ctaaaaagta aactatagta atgtggatta tcaccttcca acagtatata aaatgagcgt
      421 aaaaacggct atttttgcct taacaacgat ttttttgtat acaaatacga tatgctcatt
      481 aattattgga atttgtagtg ctgtttaaat taatgaaggt gtaattatat gagtgatcat
      541 tttgaaaaag tttgttgaga agatgtgctt ctagtcatgt gatgggagaa aataatttaa
      601 ctgttagagt gaatagttaa attattctgg ttatatgaaa aaagtagttt ctaaaataat
      661 cttgcaggga ttaacttaaa gaaattgaga gaatagtttc tttgaaattt ctatatacaa
      721 tgagaagctg aaatttactt ttatttgatg actggaaata gaaattaaat atattgtatt
      781 gttacattaa agaaaacttg tatggaaaaa tcagtacaat accattattt aatgttcttc
      841 acttaaagcg caaaaaatat cagtttatta aactcgtata tagaacaaat atatgtagac
      901 ggggcgaaac gatgagtgta aaaaaaatgc tatttatggt aagtacaata attgtattaa
      961 catcccgatt ttggggaatt aatactagtt tatctatgcg atattttatt atggcaatat
     1021 gggatttata ttttatgtta agctattttt cttatcgtga gaaaacatat aaaaaatacg
     1081 ttatcaagaa taacttttgg ttgactataa tgccgtttgt gatattttct atctatactc
     1141 taataatatg gggaattggt tcaaatgcag aatttgaaaa ttttataaag ttatgttcca
     1201 cgttgcttta tttaattctt gcatatggtt acgcatgtac agcattttac ttatttaagg
     1261 cagaaggaat tgattttatt ttttggtcag gtgttatttc atatatgagt ggttcagttt
     1321 tttatttaat tgtatcttat ggtttaaatg gtttaatttc ttatataaaa agtcttataa
     1381 caggtgaaac aaatactgca aattttgct
//
LOCUS       DARBDN010000214         1399 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000214 DARBDN010000000
VERSION     DARBDN010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.221"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..198)
                     /locus_tag="SCH06_002926"
     CDS             complement(<1..198)
                     /locus_tag="SCH06_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079416.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALECFEQYKENKRRCG"
     gene            complement(494..1366)
                     /locus_tag="SCH06_002927"
     CDS             complement(494..1366)
                     /locus_tag="SCH06_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEG1079417.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          377 a          323 c          272 g          427 t
ORIGIN      
        1 cccacaacgt cgcttatttt ctttgtattg ttcaaagcat tcaagtgctg ttccaccaca
       61 tttgagaaag ttatagacat tgtaaattgt ttggcgtcca cgtttaagct gcttcgcaac
      121 gatagcaacc ggagtttctt gatgaaaata tgcttctatc attacaagct cgtttggtgt
      181 aagatgggta taagtcattt atgttcactc tccttgtatg ctttagcggg tattacgatt
      241 tgagtgtaac ataaatggct tttttatttg tctcgcttaa ttatacaaac ggcgtgtaaa
      301 aaactattgc acaatacaag tggcctacgg ctatcgaaat ttccataact ttcgagcaag
      361 aatttatctc attcaaggct tgatcttcca agtaaaacaa aaaccagtta agcactctgc
      421 ctaactggtt atgactaaat tttcagttgt atctttctct accaacacta aatgtcgaag
      481 agcctttttt cgtttatgaa tgtaagaccg cttctcgagc caatgccaaa caaccgagcg
      541 ttccagcgtt gtcttctaat gctggggtca cgatatattt gcttaactca ggtgtttcga
      601 catacccatt gaccaatttt gcaaatgcgt cgtggacgtt ttgcagcata tggcgttgtt
      661 tcatcacacc accgccaaaa atgatcacat ctggagaaaa catcaaggtt gtattgtagg
      721 cacattgagc aatataggag gcttcgattt cccaataagg atcatcttct gcaacctctt
      781 gtcctttttt ccctaagcgt ttttcgatgg cgggtccagc ggccatccct tctaaacagt
      841 tgccatgaaa tggacagctg ccagcaaagt catcttttgg atgagggacg acgagcatat
      901 gccccatttc tggatgacta aacccttcga taaagcgccc ttcttgtaag gcaccgccgc
      961 caacacccgt accgatcgta tagtaaacga cactgctcaa tcctttgcca ctgccgaaga
     1021 catactcacc ataggcagcc gcattgacat ctgttgtcca agaaatcggg atcggaaatt
     1081 cttttttcat ggtaccgatg aaatcaaaat tttgccatgc caatttcggg gtcgaggtaa
     1141 tgtacccata agtggcggaa tcgcgatgga tatcgatagg cccaaatgag ccaatcccaa
     1201 tccctgctaa atctgcttgg tattgtttga agaagtcaat gactaaaggc attgtttcct
     1261 caggtgtcgt tgtcggaaag ctcactcttt ccttgatcgt catttcttca tcgccaatgg
     1321 cacacacaaa ttttgtgccg cctgcttcaa ttgcaccgta tagcatagac atttctccct
     1381 ttattttaga atgaaatca
//
LOCUS       DARBDN010000215         1395 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000215 DARBDN010000000
VERSION     DARBDN010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.222"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(361..975)
                     /locus_tag="SCH06_002928"
     CDS             complement(361..975)
                     /locus_tag="SCH06_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEG1079418.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          455 a          271 c          232 g          437 t
ORIGIN      
        1 tgataacaaa tgtactataa ttactttgta aagagttttg gggaagactc tttcatcaac
       61 gtgtattaag agacaagaaa gaatccatat ggattctttc ttgtctcttt ttccactact
      121 ttttattttt ctgacactac atattcttat aactcatttc tcataactgt gaaacaactt
      181 ataaaaataa caaactttaa acaaaacaag cttaaaatca aagatgatcc atcttaaaat
      241 aactaaaaca aaaaaagtag tcgttgttaa tcctcattaa taatcgtttt ctttttttca
      301 aacgctccat ttttatgtgg aacattattt ttttaaggaa ctttgtcaac atgtggataa
      361 ctattttcca cttgtgtcct ggactagctg ttttgctgta aaatacaaaa cttgctgcag
      421 caaaaagatc gttgcaagag aggctgttcc gcagatcgct ggatctagat ttggcaaagt
      481 caagactgca tcatgtaaat tggcgtggtt gtccaaaacc aaatcagcaa attcaaataa
      541 tcgcaaacca ctgctatgtt gcgatttgat acttcgtgac aaatcaaatc cagtaacaat
      601 gattaatgga tgaccatttt ctttgatcca ctgagctagt tcgatgattg ccgggtttct
      661 tccttcattc gaaagaagaa gaaaaatgtc ttctgatttg acagaaagct gatcaataat
      721 tgcctgtcct gcaccttcta gcgtttcata gacacctccg gctggatttt caatcaatat
      781 acttggtaca agatccgggg tttgatccca aaattcaaat gctacaccac ttagtgtgcg
      841 gctagcatat atctgcaatc taccaccttg attaatttgt ttcgcgatcc aagtgccagc
      901 ttgaagcatc agcggctctt ctatccttaa tttctcttcc aattggtgat aatagtcaaa
      961 ataacataaa ctcatttatc tctcccgcct agctatactt gacatgaata gaaacagctg
     1021 cctaatctaa ggaagtacat aaaaaaacag tagttagaca gtaacacatg tggtctttgc
     1081 tgtttcaaac acaaaaaagg cattgaacga atacgcccaa taccttgaca tagcaaataa
     1141 aacaacgtgc agaccatgga aaatatctac ataggggtag aattttcacc ctagattagg
     1201 tacaataaat taggtcgatg cactgcattg actatggcaa aatgatcggt cagggtgtat
     1261 gtgtgtgact ggtcattccc tgattcttag cgccaactaa gggtcaggga gccttttttt
     1321 attcagctgt ttctatctga atttattgta agtaatctct tatccaagtg caagcaagaa
     1381 aatacaaaaa aacat
//
LOCUS       DARBDN010000216         1384 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000216 DARBDN010000000
VERSION     DARBDN010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.223"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(105..404)
                     /locus_tag="SCH06_002929"
     CDS             complement(105..404)
                     /locus_tag="SCH06_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEG1079419.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            755..>1384
                     /locus_tag="SCH06_002930"
     CDS             755..>1384
                     /locus_tag="SCH06_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEG1079420.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT          465 a          222 c          197 g          500 t
ORIGIN      
        1 tttatttaga ataaaaaaat acagactctg ttcaaataaa tgaacctagc ctgcattatg
       61 agattgacta tactttttaa ttcattgaga tgaataactc gtttttataa atgcccaaaa
      121 gtaatcggtg ccgaagccat tcctcgacct aattcttttt caaattttcc tattgttgat
      181 atctccatat aaaacggtga tactggttta gacaattctc ccctgattgc taacggacgt
      241 aaactacgtt ccaaattatt tatgacttta ggataatact gacctttttc taagcctgtc
      301 tttgcgtcta tcaaaagtat acgttccttt tctttgatct ctggatttaa aacgagatca
      361 tataatttta gtaccatgtt ttctatttct tcacttttag acatcacgat ttcctcccaa
      421 aaatatattt cttcccacta cattctataa acaaagtata cgctacatct agattttttt
      481 aaatcattac tggattgtta aaacctttca atacactgtt atggcaacga tttttatttt
      541 aaaaacattc taaattaaat cagtaaaaat ttttattcta agatttttat tagaattacg
      601 cctaatttgt gtctctcagg gcaattctaa gaacgtttca agagatagcg acactatcgt
      661 tatcgaaaaa ggcgaaaacc tatctcattt tctgctaatg taagttggtt tagcttttgt
      721 taatatgact ttatgaaaat ggaggtaatt aaatatgatt tttcctaaag ttaatgaagc
      781 aagcttgaat aaaggatcct tttttcatat ctatgaaaac gaagattttg aactgtataa
      841 tatcctttca caaaaagagg tcatcgaaaa ccaaataatc tgccatccaa ttatttacaa
      901 atctattttc aagtatgcat tttttgcttc caatgatttt caaagaatgg agattaccga
      961 ctgtatattc gaaaactgtg atttttcagg ctgtatattg acaaaaagca tgttgcatcg
     1021 cgtgaaattt gtcaattgta aattaacagg tactaaattg atggaaagtt atattgggaa
     1081 cacgttattc gagaattgta aaatggacta tgtaaattta tctggttcaa acataaaaga
     1141 aagtaccttt gagcactctg tcttatcaag cgcagatttt gtagactgtt ccctcactaa
     1201 aataatgttt tctactaatg atttagaaaa tgctagcttt tttgatactg atttaaaaaa
     1261 tatcgattta agtagcaact cctttgaaat gattgaagta cgctcggaac atctaaaaaa
     1321 ttgtacgctt aatcagttgc aagcacttgg ttttgctaga aaatttttac aaataaaagt
     1381 agta
//
LOCUS       DARBDN010000217         1374 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000217 DARBDN010000000
VERSION     DARBDN010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.224"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            33..1372
                     /locus_tag="SCH06_002931"
     CDS             join(33..474,474..1372)
                     /locus_tag="SCH06_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HEG1079421.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DARBDN010000218         1355 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000218 DARBDN010000000
VERSION     DARBDN010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.226"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1355
                     /locus_tag="SCH06_002932"
     rRNA            <1..1355
                     /locus_tag="SCH06_002932"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DARBDN010000219         1354 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000219 DARBDN010000000
VERSION     DARBDN010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.227"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            44..>1354
                     /locus_tag="SCH06_002933"
     CDS             44..>1354
                     /locus_tag="SCH06_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079422.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVT"
BASE COUNT          460 a          173 c          181 g          540 t
ORIGIN      
        1 tgttttaaaa aaataaatga tactatatgt aatataaaaa aacatgaggt ggtatatgaa
       61 tttgaaaaaa attttttctg taaaaatatt tatagtttat gcatttgtta gtttattata
      121 tttatttcca gcatttaaaa acatggaaat atttggcttt tatgatacgg catttcacat
      181 taatcgtgcg ttaagtttag aatctatttt tagctcccct attaattttg aaacgtttag
      241 atcatatggc atgcaagtaa ataattttta cccatggtta actctatatc ctttattttt
      301 attgatcaag tttactaatt tagcaatagg ctataacctt tttctttata ttgttacgct
      361 cattactcta tttatatgtc attatgtaat gtatgaaatt accaaaaaac atgttactag
      421 ctcctttttc gctattatat atacaacatc ttcttttagg agtgtagaaa tatttcttcg
      481 aggggcaatg ggggaattac tcgcaatgtc aatacttcct cttattttac tcgggtttat
      541 aaagctttac gactcaaaaa aagaatcttg ggttatgttg gcgattagca tgactttatt
      601 aatttacact catgttcttt ctgtagctat gactatggta atgattataa ttgctttaat
      661 tattcaattt tatcggaaaa agaaaataga aatcttctta attattaaat taataaaagc
      721 tgctatagtt actttacttc tttcactagc gtttataggt cctatgattg agcagacatt
      781 gtatcaagat ctgaatagac cttatgtgga tatattacaa aaaagagcaa tttatctggg
      841 taaagagttt ttgattggaa gtatagattc agaattacta tcatttggta ttggcttaac
      901 tttgcttatt tgtttaatta tactaacatt taactttaaa aaattaggaa tcttatctaa
      961 aatcacttat ataatgggta taatatctat tctactttgt acaaaaatat ttccatggtt
     1021 tgccttacaa aatactcctt taaatattat tcaagctcct tggcgtttta tgatattttc
     1081 aacattgttc atatcttttt cagtatctct atttatttct ccacagttgg aaaaattttc
     1141 ttatacaagg agaagaaatt ttatactatt attaatatta gctatttcaa ttttaaatta
     1201 ttcatcagta gttaacatgg tgaaagaaat gaattttcaa ggaacttatt ctaatgaaca
     1261 aatggaaaat aaacttgaag aatttgagaa ttttgattat gtacctatag gctataaaaa
     1321 agatcaattg cttttgaaaa accatcaagt taca
//
LOCUS       DARBDN010000220         1354 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000220 DARBDN010000000
VERSION     DARBDN010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.228"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            553..1086
                     /locus_tag="SCH06_002934"
     CDS             553..1086
                     /locus_tag="SCH06_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HEG1079423.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          430 a          249 c          254 g          421 t
ORIGIN      
        1 ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag
       61 gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa tagttcctca
      121 tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattga
      181 gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca aaatagttcc
      241 tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg
      301 gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg aaaatggttc
      361 ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca tctaactcca
      421 aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat aaaaaattct
      481 atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat ttcccaagga
      541 ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca tcagccttat
      601 agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga tgaattctat
      661 acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca cggaatccat
      721 caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat ccaaccatat
      781 tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa ggtcttagcg
      841 ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg tacagtgaaa
      901 agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt gtgcgaaaat
      961 ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc atgtgcggaa
     1021 atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact tgtgactata
     1081 aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt tcactccgag
     1141 tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt gactggtgac
     1201 cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct gttctgcatc
     1261 aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg ttggacttat
     1321 taccgcagat gcaagctttt ggacaccgtt tacc
//
LOCUS       DARBDN010000221         1306 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000221 DARBDN010000000
VERSION     DARBDN010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.230"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            24..>1306
                     /locus_tag="SCH06_002935"
     CDS             24..>1306
                     /locus_tag="SCH06_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEG1079424.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTK"
BASE COUNT          407 a          285 c          261 g          353 t
ORIGIN      
        1 accattcaaa ggagtgtttc aagatgtcct attcagagtt taccaaagag ttactagata
       61 ttctagacct aaatcttacc tttcatgaag atgcctttcg caaagagcgc attaatgacg
      121 aaacatgttt tgtttttgat ggcacattga cctatcaacc agaggaatgc ttccattgcc
      181 actatcaaaa taagcaaacg atcattaaat ggggctggaa aaaagtatcc atcttattga
      241 atgatgtcag taactacaag accattgtgc ggattaacaa acagcgcttc aaatgtaaac
      301 actgtggaaa gactttttta gcagaagatt cagttagcga tcgtcgctgc tccattgccc
      361 gcagagtcaa acaagccatt cttgagctat taagtgagcc tatttctatg tctttgattg
      421 cacgtatgaa gcacatttct ccgaccactg tcattcgaat acttcgcagc cttcggccta
      481 aaaccgtttc tttgaaccag ccgttaccag aagtggtgtg tttcgatgaa ttcaaatcgg
      541 tgaaaaacgt ctcgggagcc atgagctttg tcatgatgga cggcaagacc catcaactga
      601 ttgatattgt ggaaaatcgg caactcaatc ctttacgcga ctatttcttg cgctacccta
      661 gaaaagtccg tgaacaagta cgtctagtgg tttcagattt ctatacaccc tatcgcacat
      721 tggtgaaaga gtgttttccg aatgcccgaa tcgtcgccga tcgctttcat attagccaac
      781 acatcggtcg ggcctttacc aaccaccgaa ttcaagtaat gaagaccttt aaaaaagggg
      841 atcgtcggtc gaagcactta aagaaatact ggagactact tcaaaagaat gcgtgggaat
      901 tgaatggtca gcatcgctac tggcgtccgt catttcgaga tcatctgaca gaagcggaga
      961 tagtcgatcg gctattatat tatgatgact ccttaaagcg aggctacgaa gtctaccagg
     1021 tttttctttc cgctatcaga agacaagatg ttcctgaatt cgtcgcgctc ctaaaagaag
     1081 actacaagga gttgccagag cactatcaac cagtgttcac gaccttcaag aaatatcgaa
     1141 cagaaatcaa acgagcgttg cgagttccct attccaacgg ccctatagaa tgtttgaaca
     1201 accatatcaa agtactaaaa cgaattgcct atggctttag aaactttcaa aactaccgag
     1261 aacgaatctt tttatatcga ggaaaatatt tcaagaaaac taagaa
//
LOCUS       DARBDN010000222         1299 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000222 DARBDN010000000
VERSION     DARBDN010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.231"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..396
                     /locus_tag="SCH06_002936"
     CDS             <1..396
                     /locus_tag="SCH06_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEG1079425.1"
                     /translation="FAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKK
                     KKVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLT
                     TEQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            356..634
                     /locus_tag="SCH06_002937"
     CDS             356..634
                     /locus_tag="SCH06_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079426.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            641..>1299
                     /locus_tag="SCH06_002938"
     CDS             641..>1299
                     /locus_tag="SCH06_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079427.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     V"
BASE COUNT          523 a          224 c          233 g          319 t
ORIGIN      
        1 tttgcgattg atcaaacaat gaaaaacaaa aaaactcgaa cgtataacca attttgtgat
       61 tctcttaaaa cattcggcat tcattgcttg aatcgtggga aaaattttac ttacgaattg
      121 atccacaaaa agaaaaaagt acgatccaac aaactaggaa aggattacga aaaggagacg
      181 attttacatg agctggacag acgagaacga gcctacaatc aacaacgaac caacgagcta
      241 cgaagagctc gagctagcat tcgcgaaact gcaaaagaag tacgaagaga acaacgaact
      301 cttacgactg aacaaccgga aattagaccg actcgaagaa accatgacca acacgttgaa
      361 agaggagcag actaccaaca agaattatcg ttctaaaacg ttacaagaca tagaaaatga
      421 aataaagaaa caacgtgctt ttcttgcacc ttataccaaa gaaagaatac aaactacaat
      481 tgattcacaa gtcaaaaaat tccaccatgc gctattaaac cagcgaaata aagaacagaa
      541 aaaagtaatt atgcagcgat caatggatat tcttgccccc ttatgttgct taatcatgac
      601 actgttagcc ttttggctgg tatggggaga ataaatagaa atggcattct atttacccta
      661 tctactcatt tttgccagta ttttaggaat tatttggctt agctataagg cttatcaaac
      721 aagatattca ttaaaaggct ctaaaattcg atttaagagg tttttgttgc caggggttat
      781 atttacatta tcaatcgttt taagtggttt attcggcgtt ttagagggaa ataaacgtat
      841 ttcaagaagt attttattag gggatatcac tcaaaagtat gaagcagcat gtgataaaaa
      901 gaaaaaggag caagtgttaa cacaaaaaat ggaagagttt accacttgtt atgaggaaat
      961 gaacgatatt tttgtgaatc aagaaaaacg tttgacggat aaaaacatgg aaaaactcac
     1021 tcgtctttat caaaacttgc cagaaaaaca gcaaaaagag gttcaagaca actatgagcg
     1081 aaccaaaaaa gacgtgcaat attttaaaga tacgcagaca gaagaagctt gttataattt
     1141 attcagtgat acaatccctt tttcaactag tgaacaggaa cgaaaagaac ggcaacaatc
     1201 agttacctac gaacgttata aagcactgct tcagcaagca acgaacatac aaaatccaac
     1261 gaaaaaagaa acggcattaa attatctaaa aagtgtcaa
//
LOCUS       DARBDN010000223         1294 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000223 DARBDN010000000
VERSION     DARBDN010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.232"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1244
                     /locus_tag="SCH06_002939"
     CDS             <1..1244
                     /locus_tag="SCH06_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEG1079428.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DARBDN010000224         1293 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000224 DARBDN010000000
VERSION     DARBDN010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.233"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(61..279)
                     /locus_tag="SCH06_002940"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="SCH06_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="SCH06_002941"
     CDS             complement(545..739)
                     /locus_tag="SCH06_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079429.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(839..925)
                     /locus_tag="SCH06_002942"
                     /pseudo
     CDS             complement(839..925)
                     /locus_tag="SCH06_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          459 a          217 c          175 g          442 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattgtac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta ttacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaa
//
LOCUS       DARBDN010000225         1257 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000225 DARBDN010000000
VERSION     DARBDN010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.234"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..603)
                     /locus_tag="SCH06_002943"
     CDS             complement(<1..603)
                     /locus_tag="SCH06_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEG1079430.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEIN"
     gene            complement(603..>1257)
                     /locus_tag="SCH06_002944"
     CDS             complement(603..>1257)
                     /locus_tag="SCH06_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEG1079431.1"
                     /translation="KDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWH
                     PWEDYRNFFVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFT
                     LIIEHETGIVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQ
                     LYDEVMHDNNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT          430 a          214 c          141 g          472 t
ORIGIN      
        1 gttaatttca agattcgaat atttaccaaa ctgttttttt actgatttag ggaaaccaaa
       61 taggtttata atataatcca attcatgtat acagtctaat tctactcctc cccccataga
      121 tttaaaggca gaataattat ttctataatc agtacctttt ctccaatcag gaagataagt
      181 agaacaaata gctcttacag aatatacttt tttactttga atactattac gaacaacttc
      241 catgatattt ttatacctca gtggagcagc aacataaata tttttgtaat cataattata
      301 ttgagtaaga tcaatactct cagaaaaagc aggtttttct aaaaatatgt aatcaacttt
      361 ttcaacaatt acatttagtg tttccagatg cttaaaagtc ggatttgtaa taaaagctat
      421 atcataatgt gtatccaaat cgtctctatt ttgaatatac gttatttctt caaactcttt
      481 ttttccactg ctactataag ctgttatatc aaaattaata gaattctttt ttccatagct
      541 tattagattt tttagatgtc tctttccaat tgaccctaac ccaaaaaaaa ttactttcat
      601 cattaattta cctcaatgtc gttaattaag ttaataatat acttatcttt ttcaaaagta
      661 tattggggtt ccattttctt ttccaaaagc gtgaaaaatt ctttaatctc ctctaaatat
      721 gcatcttcaa taatagtatg tgaataatta ttatcatgca taacctcatc gtacaattga
      781 atatctgtca tactagaagt ttcttcattc catgaaaata gagaatccgg gttaccttcc
      841 cattctatta aaatcttttc accaattata gttaaatttc ttttagctac tcttgaaaca
      901 acatctacac ttaaagttcc aactatacca gtttcatgct caataataag agtgaaactg
      961 tccgaataat caatatcaag attggataat ttctgggtca ttacagtaaa cgatttaact
     1021 ttcccaaatg tatctataat ccaaggtaat tcaatagcga atatttctct acacccatta
     1081 gtttttttgt ttgaaacaaa aaaattgcga taatcttccc aaggatgcca gtcgggtaaa
     1141 tactgtccta catggtattg ataagaaatt tttttattat gcgtcacttt agacttaata
     1201 tattgaattt cttttctctt caaaaatgta gaagatagat aaagtaatct atctttc
//
LOCUS       DARBDN010000226         1249 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000226 DARBDN010000000
VERSION     DARBDN010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.235"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..626)
                     /locus_tag="SCH06_002945"
     CDS             complement(<1..626)
                     /locus_tag="SCH06_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079432.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
     gene            914..>1249
                     /locus_tag="SCH06_002946"
     CDS             914..>1249
                     /locus_tag="SCH06_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEG1079433.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDS"
BASE COUNT          412 a          200 c          238 g          399 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattagaa aaaagaaaaa gtattggcaa cagaaggtgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattct
//
LOCUS       DARBDN010000227         1246 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000227 DARBDN010000000
VERSION     DARBDN010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.236"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            200..742
                     /locus_tag="SCH06_002947"
     CDS             200..742
                     /locus_tag="SCH06_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079434.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="SCH06_002948"
     CDS             898..>1246
                     /locus_tag="SCH06_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEG1079435.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DARBDN010000228         1226 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.237, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000228 DARBDN010000000
VERSION     DARBDN010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.237"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(76..1170)
                     /locus_tag="SCH06_002949"
     CDS             complement(76..1170)
                     /locus_tag="SCH06_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEG1079436.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT          359 a          263 c          193 g          411 t
ORIGIN      
        1 cctataaaaa aacaaaataa aaaagcagaa ataactggct atttctagcg gattatttct
       61 gcaataacta attatctatt ttttattttc aattaattta aagcttgacc atggtttcaa
      121 aaagtcaagg aggaataatt cgtcatcgga gattcttcct acaacattga cacgtccgtc
      181 gtttttcata tccttcaagg cgatttgtgt ttctcctttg tattgaccgt acccttcatt
      241 gtcaatcagt acatccccat gatgcatatc tcgcgtatta tgaggcggga aatctttatc
      301 tttgtagtat acacgagtca tcgttgaacg aaggatatat tctgagcgat cccctcgata
      361 actatgaagg ttatcaaaca agcagattcg ttcgttttct gtaatacctt cttccgtatc
      421 tactttcaat gttggataat ccgcgttaaa tgcttctgcc atttctttca attcttcttc
      481 acttgcgtac gcatttccaa tagaaatatc atcaatcaat cctgtaagga ttaaatgctt
      541 cacttgtgtc gcaatttcaa gatctcggtg gtcttccagc gtgcacaagc catcttgcgt
      601 aggccaaggg ccaaactcag cagattgcga attgacgaat gccatcgtat tcaaattata
      661 ttttctgaat ttttctgaac aaaaaacaaa gtgttcgtat cctaaaccag agtatcgatg
      721 aggataaaaa ttatgagaac ctaataaatt atccgtgttt ggcgaataac tcatgatgtt
      781 gtcaacgtaa ttcgtgcccg aactcatatt gatctcgatt ttgataccaa aaggattgcg
      841 cgtcattttt gcttcttctg ctcctgtgaa tccgatatct aagcggaccc cgtaggcacc
      901 catcttatgg aaaaaagata agtcatcgta agaaatctcc aactgttcaa ataacgctgg
      961 attgatatca accattactt ccatgcctag gctattcgcg taatcaacta cttctttaaa
     1021 ttctgaaaga actttttctt tatcatcatt gatctgcagc aaactggtaa aaacccgttt
     1081 atacccatac ttatgagcta aatccaagta cgctttgtcc ttttcaaatg ttgaccgttc
     1141 tggataaatc gagattccta attttcccat attaccattt cctcctgcat cttttcgttt
     1201 ttgtatccac ttacattata gcaaac
//
LOCUS       DARBDN010000229         1211 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000229 DARBDN010000000
VERSION     DARBDN010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.238"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>1211
                     /locus_tag="SCH06_002950"
     CDS             <1..>1211
                     /locus_tag="SCH06_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HEG1079437.1"
                     /translation="QKKKTLIVDAVFSPAPHTCRNCGSTVVDGNGKVIVVKNGKKETI
                     VRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSYFVQPRHSIANHVRYKIASLLTEKV
                     SLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRSHASIEDKMSFIC
                     ADGETGQLIDVLPTRKLPRLTSYFLGCANPEEVKFLVTDMNAAYFQLTKRILPNAKVV
                     IDRFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLLKNRANINHYEYKT
                     WKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDKDPDLFFSLLAELP
                     ETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMKRVSYGFKSFENMR
                     IRIFLINQLIK"
BASE COUNT          403 a          235 c          232 g          341 t
ORIGIN      
        1 ttcagaagaa aaagacgttg atcgtcgatg ctgttttctc acctgctccc catacctgta
       61 gaaattgtgg ttctactgtg gtagatggaa acgggaaagt aattgtagtg aaaaatggga
      121 agaaggaaac gattgtccgc tttgaacaat acaatcacat gcctttggtt atgcgcttaa
      181 aaaagcagcg ctatacctgt aaaaactgtc gaacccattg gacggctcaa agttattttg
      241 ttcaacccag acattcaatc gcgaatcatg tcagatataa aattgcttct ttactgactg
      301 aaaaagtatc tttatctttt attgcgaaaa attgtcaggt atctttgacc accgttattc
      361 gtacgttgaa agagtttaaa agctacttac caaagcaatc taagaggatt ctccccagag
      421 tattgatggt tgatgaattt cgttcgcacg cttccataga agataaaatg agctttattt
      481 gcgcagatgg cgaaacagga caattaattg atgtcttgcc tacgcgtaaa ttgcctcgat
      541 taacaagcta tttcttaggc tgcgctaatc ctgaagaagt aaaattttta gtcacagaca
      601 tgaacgccgc ctacttccag cttaccaaac gtattctgcc aaatgcgaaa gtagtgattg
      661 atcggtttca tattatcaaa cacatgaatc aagcctttaa tgagttgcgt atccgtgaaa
      721 tgaatgaact tcgtaaagta ggacagaaaa gtcaggcaga aaaactgaaa aagaactggc
      781 gctttttgct aaaaaatcgt gcaaacatca accattatga atacaaaaca tggaaaagtt
      841 ttcgagcacc aaaataccca tttcttacgg aagcgatgat gattgatcga ttgcttggct
      901 tttctacgtc cctgaaggag gcgtatccct attttcatga attagttgaa gcctttcgag
      961 acaaagaccc tgacttattt ttctccttat tggcagaact tcccgaaacg ttagatgacg
     1021 gctttcggga aaagctccaa aaccttctga cctatgaaga aggcatcacc aacgcgatga
     1081 tctatcctta caccaatgga aaaatagaag cgaagaatac ccatataaag acaatgaaac
     1141 gagtatccta cggatttaaa tcatttgaga acatgagaat tagaatcttt ttgatcaatc
     1201 aattaatcaa a
//
LOCUS       DARBDN010000230         1193 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000230 DARBDN010000000
VERSION     DARBDN010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.239"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1076
                     /locus_tag="SCH06_002951"
     CDS             <1..1076
                     /locus_tag="SCH06_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEG1079438.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DARBDN010000231         1190 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000231 DARBDN010000000
VERSION     DARBDN010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.240"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..855)
                     /locus_tag="SCH06_002952"
     CDS             complement(<1..855)
                     /locus_tag="SCH06_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079439.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGT"
BASE COUNT          391 a          214 c          120 g          465 t
ORIGIN      
        1 tgttcctata aaatcaagtc ctctacattt taaaggttca cttaaactat taatatagtt
       61 aataatgttg tctatccttt tctctttatc ttcaccttca atctggggag catatagtcc
      121 aatttcctcc caataatatg aatctctttc aattcccatg atggtagctt tggctaattt
      181 caaatcaaat aacgatttta gaattcttag tgtctcaata aagtcttctc tcttcaactc
      241 tttaatccat tgtgaatttt ctggattatc taaaatttca agttcatctt cattataagt
      301 atatttcaaa tttgacttgc ttaactcata gataaatgaa gtttcttgac tcataattct
      361 tttaagtact tgactataag tttcgtttga ctttgcccat ttcgctaatt ctaccactgt
      421 attcactaat aaatcgaaat aatgatgttc tcgttcaata gtctcagcat tttgaaaatg
      481 aaaatcacct ttataaactc cattcttttc cactgtttta ttaatatttt ttaaaaacca
      541 gaatgagttt gcaaatttag tcgtactttt tcgattaact aagttaataa ctcttccatg
      601 taataataag acaaaaatac ataaattttt agcttcctta ttattagata ctaattgatc
      661 aatcataggg agccattttt tgattttcac taattgattg ctcataaatc tttcactgga
      721 cttttgttca atcttaaatt gcaaaacttc taactcataa ttcccatctt ctgatttatt
      781 tttgggaaca actatcaaac ttttataaag tttatccaca tcaaaattta tcttttttgc
      841 ataatttgta gccattaata catctcctta ttcataataa atttcatatg acgctcctct
      901 caaaatttac cggtagacta gaaaaaagaa taaaagatac gtcaattcac actttattct
      961 taaaaaaaaa ctggtctctc taccggtaat atcgattgag tccgccttta tcgactttat
     1021 ccttttttta tattaaattt tttcaccggt agacagggag agaaagaata aactaaaaag
     1081 cccttaattc ttaatgtttt cacctcctta ccgttcctac cgctaaaatt taatataact
     1141 aaattctata acattagaag aaattttaaa tacctttgat aaaaaatatt
//
LOCUS       DARBDN010000232         1167 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000232 DARBDN010000000
VERSION     DARBDN010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.241"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>1167
                     /locus_tag="SCH06_002953"
     CDS             <1..>1167
                     /locus_tag="SCH06_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HEG1079440.1"
                     /translation="QKKKTLVVDAVLSPTPRACRSCGSTVVDGNGKAIIVKNGKKETI
                     VRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSYFVQPRHSIANHVRYKIASLLTEKV
                     SLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKILPRVLMVDEFRSHASIEDKMSFIC
                     ADGETGKLIDVLPTRKLPRLTSYFLGCTNPEEVEFLVTDMNAAYFQLTKRVLPNAKVV
                     IDRFHIVKHMNQAFNELRIREMNELRKAGQKSQAEKLKKNWRFLLKNRANINHYEYKT
                     WKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHELVEAFRDKDPDLFFSLLAELP
                     ETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSF"
BASE COUNT          383 a          234 c          226 g          324 t
ORIGIN      
        1 ttcagaagaa aaagacgttg gtcgtcgatg ctgttctctc gcctactcct cgtgcttgta
       61 gaagttgtgg ttctactgtg gtagatggaa acgggaaagc aattatagtg aaaaatggaa
      121 aaaaggaaac gattgtccgt tttgaacaat acaatcatat gcctttggtt atgcgcctaa
      181 aaaagcaacg ctatacctgt aaaaactgtc gcacccattg gacggctcaa agttattttg
      241 tccaacccag acattcaatc gcaaatcatg ttagatataa aattgcttct ttactgactg
      301 aaaaagtatc tttatctttt attgcgaaaa gctgtcaggt atctttgacc accgttattc
      361 gtacattgaa agagtttaaa agctatttac caaagcaatc taagaagatc ctccccagag
      421 tattgatggt tgacgaattt cgttcgcatg cttccataga agataagatg agctttattt
      481 gcgcggatgg cgaaacagga aaattaatag atgttttgcc tacgcgtaaa ttacctcgat
      541 taacaagcta tttcttaggt tgtaccaatc cagaagaagt agaattcttg gtgacagaca
      601 tgaacgccgc ctacttccag ctcaccaaac gtgttctgcc aaatgcgaaa gtcgtgattg
      661 atcggtttca tattgtcaaa cacatgaatc aagcgttcaa tgagttgcgt atccgtgaaa
      721 tgaatgaact tcgtaaagcc ggacagaaaa gccaggcaga aaaactgaaa aagaactggc
      781 gctttttgct aaaaaatcgt gcaaacatca accattatga atacaaaaca tggaaaagtt
      841 tccgagcacc aaaataccca tttcttactg aagcaatgat gattgatcga ttgcttgagt
      901 tttctccgcc cctaaaggag gcgtatccct tttttcatga attagttgaa gcctttcgag
      961 acaaagaccc tgacttattt ttctccttat tggcagaact tcccgaaacg ttagatgaca
     1021 gctttcggga aaagcttcaa aaccttctga cctatgaaga aggcatcacc aacgcaatga
     1081 tctatcctta ttccaatgga aaaatagaag cgaagaatac ccacataaag acaatgaaac
     1141 gagtatccta cggatttaaa tcatttg
//
LOCUS       DARBDN010000233         1165 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000233 DARBDN010000000
VERSION     DARBDN010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.242"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            81..491
                     /gene="spx"
                     /locus_tag="SCH06_002954"
     CDS             81..491
                     /gene="spx"
                     /locus_tag="SCH06_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEG1079441.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            505..861
                     /locus_tag="SCH06_002955"
     CDS             505..861
                     /locus_tag="SCH06_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HEG1079442.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          412 a          165 c          219 g          369 t
ORIGIN      
        1 tttatatatt attagctaat aattggtatt ttaaaagaaa ttactgtaga attggattat
       61 aattaaaaat gagtgagaaa atgataaaag tatatacttc gcctagctgt acttcctgta
      121 gaaaagcaag agcatggttg caagcgaatc aacttgaatt tgaagagaag aatatttttg
      181 ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc agcgactgaa ggaggagttc
      241 aagatattat ttccactcgg tcgaaaattt acgaaaagct gggcatagat tttaacgaat
      301 taactttaaa gcaaatgatc gtcttattca aagaatatcc ttcattattg agacgaccta
      361 ttttgattga tgaaaaaaga atactaatcg gatttaatga agatgagatc cggtcatttg
      421 tccctcgtga aattcgatgt gttgccagaa atctgatcta tttacaaaac aataacatct
      481 taaattcata gggagggagc cttcgtggaa gtgaaagtct atggatcagc gcactgtgta
      541 acaagtctga aggcgaaaca atggttagaa caccatcaat tgccttatca atttgttgac
      601 ttagaagaac gcgatctaag tacagaagaa gcagaagaat tatgcagttt tgaagaagtg
      661 caagcagaac agctatttgc gacttggtct gaggcttttc acaacattgc gattgacctt
      721 tcctgtgtag gaaaaaaaca actgattttt ttatgcacac aacataccaa tctcctcaga
      781 cgtcctttga ttattatcga tgaagttcta tttattggat acaatgagca gttgatggaa
      841 cagcttatct taaataaata gactttaact gttttaatca agtcactgag catttcatac
      901 agttgtaaca gtcgaacact tagcatcaag cgtgttatgt gttctttttt tgactttatt
      961 tttctactat agagacatgc tcaatttatg tggtcaaaat tcaaatctag gtggggatat
     1021 agagttaaaa atatattgac atgtgtaaat ttacatgata tattcatttc tgttgtttta
     1081 agtagcaaag caataaaata gtattttaaa aaacatataa aatagttgtt gacatgttag
     1141 aaatgacatg ataagataac tgagt
//
LOCUS       DARBDN010000234         1143 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000234 DARBDN010000000
VERSION     DARBDN010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.244"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(18..923)
                     /gene="xerC"
                     /locus_tag="SCH06_002956"
     CDS             complement(18..923)
                     /gene="xerC"
                     /locus_tag="SCH06_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HEG1079443.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
BASE COUNT          338 a          232 c          194 g          379 t
ORIGIN      
        1 tgttcttttc cttattttta cgctcttgga tggaaagaac gatagttttt ttgtaaactt
       61 tcttttgtta catgggcata gatctgggta gtcgataaat tggcatgtcc tagcaattct
      121 tggactgtcc gcaaatctgc cccattattt aataaatgag tagcaaatgt atggcgcagc
      181 atgtgaggat ggatatcact atccaaactg ctttttttga tcatttgatt caagacatat
      241 tcaattccag taggcgtgat tggttttcca tgatgattca caaaaacgat atcatgctct
      301 tcgtgatatt ttgtcatcaa tacctggcgg ccttccctga aatattcttg cagagcatct
      361 tgagcaaaag aacctagagg agcatatctc tctttgttcc ctttaccatg gatcaacatg
      421 acctctgaat caaaatcaat gtctgatacc gacaaactgc tacactcact taaacggatg
      481 cctgacccgt aaaggacttc cagtaaagcg cggttcctca aatccaaagg actatctcct
      541 gctacgctgt caaaaagtgc ttgcatttca ttttcataaa aaaaacgtgg cagtctcaaa
      601 tttttctttt tgagatgaac gtaagaaaat ggattttctt ttatcacttc ttctttgaga
      661 agatactgat aaaacgaacg taggctggct atcttgcgac tgatagaatt tctgctatag
      721 ctaggacgat gatcagctaa tgcactcaaa tagacacgaa ccgtaaaata ttccgccttc
      781 agcagatcag cgtctccaga ttcctccaaa aaatgtttga aatggagaat gtcttcttca
      841 tatgcttctt tcgttttttc tgaatatcct ctttcgacaa tcaaataacg caaaaatttt
      901 tgttcccacg tggcttctgt cattttctca ccttcctttt gtcccagaga ataatttagc
      961 acagcgttta taaaaagaca aataaattgt cagaatttaa ccaatatttc taagtttgtt
     1021 cacaattggc gcaattcctc acattttgtt tgagaaattc ttaagaaaaa cgcaagaaaa
     1081 agggctctat aatttatggg actgatgaat cagaattgat tcttcagccc cattttcatt
     1141 tta
//
LOCUS       DARBDN010000235         1139 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000235 DARBDN010000000
VERSION     DARBDN010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.245"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..784
                     /locus_tag="SCH06_002957"
     CDS             <1..784
                     /locus_tag="SCH06_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEG1079444.1"
                     /translation="VQIFYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPV
                     KIKWMVSILLVLLVYFSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVIL
                     QHSSDNSEISAGRFTIWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNE
                     LKRAHGNMHNGFLQVLVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIF
                     ILSIFIDEMVEAHVLFNKRDVISIVFWYYLGSISYLYLKKEN"
     gene            786..>1139
                     /locus_tag="SCH06_002958"
     CDS             786..>1139
                     /locus_tag="SCH06_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079445.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLN"
BASE COUNT          380 a          140 c          189 g          430 t
ORIGIN      
        1 cgtacaaata ttttatatta cactttcttc gtctagaggt gcccaggtag taatttgttc
       61 ttttttagta ttatttcttt tgttgtttgc caattcaaaa tttagaaaga gcattagaga
      121 agtactacct gtaaaaatca aatggatggt aagcatatta ttagttctat tggtatattt
      181 ttcttttggt actaattatg ctaaggattt tttagcaaca attcctgtat cgattgatag
      241 aaaagtagaa gttatagagt caaatgaatc agataaaact ccacttccag aaaaagaagt
      301 aatattacag cattctagtg ataactccga aatttcagct ggtcgtttta cgatttggaa
      361 agctgcgctt aaagttataa gaccaacttt gttatttggt tatggagaga ccgatttcta
      421 tgggaatagc gatgcaaaat ttttgaaaaa agtagatctt gatactacag atgtgaatga
      481 actaaaaaga gcacatggaa acatgcataa tggatttctt caagtacttg tatcaagtgg
      541 tataattgct tttatatgta tctatgcttt ctatgtgtta aatatcttta gtttactcaa
      601 aacatttttt agaagtaaag tgaattatgc gtttcttggt attgttttaa tttttatact
      661 atctattttt atagatgaaa tggtggaggc tcatgtactt ttcaataagc gcgatgtcat
      721 ttcaattgtt ttctggtatt atttgggaag catttcttac ttgtatttaa aaaaggagaa
      781 ttaatatgaa gacagctttc attgcttgga ctcctttaca tttgattaat atattaaatg
      841 tttatcaaaa tttttaccga gaatcaaaag gagatttatt tatttattct gaatttgaaa
      901 acgctagaag atatagtgag cgtataaaag aattagggct atttaatgat gttgtttttg
      961 tgaatcaccg gaaaatcggt tcttccttta aacgtaaaat taacttgtta actaaccata
     1021 atcaattttt ctcggatgat ttatccgttt atgatgaaat ttttatacag ggggaaaatt
     1081 atttcacaaa aatacttttc tccaatgttt acaaaaaaaa tccagatgta aaactaaat
//
LOCUS       DARBDN010000236         1121 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000236 DARBDN010000000
VERSION     DARBDN010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.246"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            115..807
                     /locus_tag="SCH06_002959"
     CDS             115..807
                     /locus_tag="SCH06_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEG1079446.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
BASE COUNT          495 a          126 c          165 g          335 t
ORIGIN      
        1 atccttttta aataattttt tagacaaaaa acagaaagtg tctaaagaaa gcttgacgaa
       61 gaaaataatt tttaataact tatttaagga aattttttga aggagaagat aaaagtgaga
      121 aaaaagatta ttattaatgc tggagtaatt ataggattga tgttagtaat tttctccgga
      181 aagcaatatg ctgataatat tttattatgg ggaggggaag ataatattga aaagatcaac
      241 aacaatttaa ctatattaga cacagctcta gaaaataaag agcaaaaaat tagtatttta
      301 aattcacaat tgtcttcaaa caaccaaact cttgaacaac taagaactaa tattgaagtt
      361 tccaaacaaa aagtggcatc tttagaaaac gacaagaatc aattagtatc agagaaaact
      421 aatttagaaa atcaattgtc agcaaaagac tctgaattgc aaggaaaaca aaatgaaatt
      481 aatgcgaaaa tagacgaaat taaccaaaaa gtagctgaaa taaatcgatt aaatagcgat
      541 tggaataatc gtttacaaaa tgaaaagaac aaatttaatg aagaacaatc tactattaat
      601 agtttaaacc agcaaattaa tcaaatgttg agtgaaaaaa ataacattca aaatcaactg
      661 caagctactc agcaaaagct agaagaagaa aagtcaaaaa atagtagttt gaataattac
      721 attgaaaagc ttcaaaaagc taaaaatgat gtagaggata ccgcaaataa agcacaacaa
      781 attgtaaatg aacatacaat ccaatagata tagttttaat ttaacaaatg gtatgtttgg
      841 agataatgag atagaatata aatgtcataa tattatacaa tctaaacacc gtttcctttt
      901 ctatttttga tgacatcagt atatagctac tcgaaagagt agtcttttta ttattctcgc
      961 ttattattga tatgaaaatt tcgatttgac aaaaggtacc gaataatttt gtaatatgaa
     1021 ttattatcaa gaagtaatta tgatgataac atatggaaac tagttagtaa taataacagg
     1081 tgattaaact tttgaacgac ttgtaattct atattttttc t
//
LOCUS       DARBDN010000237         1116 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000237 DARBDN010000000
VERSION     DARBDN010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.247"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..899)
                     /gene="vanY"
                     /locus_tag="SCH06_002960"
     CDS             complement(<1..899)
                     /gene="vanY"
                     /locus_tag="SCH06_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEG1079447.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHT"
BASE COUNT          328 a          228 c          159 g          401 t
ORIGIN      
        1 ttagtatgtg ttgatccggg aaacactgtc acaattacac cgtctatatt gtttcctgat
       61 atctcataac gaagattagt cggcacatga atggtggtat ttttagtaac aggataataa
      121 aagatctcat atttttcccc atttacacta acagaaatgg ttttttcttc ttttaggtaa
      181 tccatatatt cctcgagaac gaaattcttt tctttcataa tcgcactatg tggtaaacca
      241 acatagcgaa tatgccatgg ttcatattga attcctgtta actctgtttt gtcctctgga
      301 taacgtaaaa tgaacccgta tttccaagca ttttcttcta tccactttcc ttcaggggct
      361 cgttccattt tcgtcaagct tgatcctaca tctagtgata aacctgaatt atgctcacta
      421 taacctgctg gtaaggcata ctcagccccc atttcttggt aaagcacact ttgctcatca
      481 aagtctcgat agccactatt aataataaaa tgactaacgc caccctttac agcatcattg
      541 accatctctg aaaatttttg tgctatttct tttgacatat aaatattact atcaagcaac
      601 ccgtatccat ttattaattc gtcatgttta gataaattca cgatatctga cttcacactt
      661 tcttggcgaa caggatattt actattgatt aatagcagat ttccttgata aacctgttct
      721 tctgtaattg ttttctcttg ggtattttca gaagtcccac tattttctaa atgttctttg
      781 ggattttgat cataattttg aaattcgact ttttcctgag aaaacagtgc ttcattaacg
      841 tagtcataac ctaagtatat taagaataac aataacaata aaaaaaacaa cttcttcatt
      901 ttcagtctcc tccttaacta tatagttgga agtatgaaat atttctagaa tcttcccctt
      961 aaacggcaca atctcgtttg agattgtgcc gttttgcccc gtaaattaca gtcaattatt
     1021 tcgccctact ggatttacta ttatcaccaa tgtagatgaa ttttcataag tgatacccat
     1081 gctgaattta acgaggctga actgcctgtt gacaat
//
LOCUS       DARBDN010000238         1105 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000238 DARBDN010000000
VERSION     DARBDN010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.248"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..1087
                     /locus_tag="SCH06_002961"
     CDS             <1..1087
                     /locus_tag="SCH06_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEG1079448.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          402 a          192 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaa
//
LOCUS       DARBDN010000239         1085 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000239 DARBDN010000000
VERSION     DARBDN010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.249"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            256..>1085
                     /locus_tag="SCH06_002962"
     CDS             256..>1085
                     /locus_tag="SCH06_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEG1079449.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          382 a          152 c          185 g          366 t
ORIGIN      
        1 aaggtaataa gttattcttt tattactatg tttgggtttt atagcaaaga aagtttaata
       61 agagtttgga cctagcaaac aatattaatg aggtcattaa atcttattat ctttagtgat
      121 ataacgaaat atctacacag acaaaatgat agcgtaaaat attttgtgta aatagatatt
      181 tagggtagaa aaaaagaaag tccattctgt aaaattaaag ttaccacaac cgaaatttta
      241 taggaggact ttctcatgcc caattttact acagaaatta tggaaacact aatcaataaa
      301 ggtgatttag atgaattatt tcgatgtcat ttagaattag ctgttaattc attattgcag
      361 gctgaattaa cagcttttct tgattatgaa aaatatgatc gtgctgggtt caattcaggt
      421 aattcccgta atgggaatta ttcacgttca ttcagaacag agtatggaga attaaatttg
      481 gtaattccta gagatagaaa tggtaagttt tctcaacaaa ctttacctgc ttataaaaga
      541 accaatgact ctttagaaac cactattatt cagctatttc aaaaaggaat tactatgtct
      601 gaaatctctg aattgattga aaaaatgtac gggcatcact atacgccaca aaccatttca
      661 aatatgacta aaatagtttc tgaagatatt attgccttta aagaaaggtc cttagaatcc
      721 agatactctg tcatttttat ggatgctact cacattcctt taaaaagaca aactgtttca
      781 aaagaagcag tttatattgt aattggcatt cgattagatg gaaccaaaga ggttcttggg
      841 tttagtcttg ctccaactga atctgcttat gtttggaaag agattcttca agacctaaaa
      901 gaccgtggtt taaaagaggt tttattagtc gtaactgatg gtttaagtgg cattaacgat
      961 agtattcata gtgtttatcc aaatgctcaa tttcaacaat gttgtgtcca tatatctaga
     1021 aatatcgctc ataaggttcg tgttagtgat cgacaagaaa tctgtagcga tttcaaatta
     1081 gttta
//
LOCUS       DARBDN010000240         1069 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000240 DARBDN010000000
VERSION     DARBDN010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.250"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..969
                     /locus_tag="SCH06_002963"
     CDS             <1..969
                     /locus_tag="SCH06_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEG1079450.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DARBDN010000241         1062 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000241 DARBDN010000000
VERSION     DARBDN010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.251"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(37..993)
                     /locus_tag="SCH06_002964"
     CDS             complement(37..993)
                     /locus_tag="SCH06_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079451.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DARBDN010000242         1051 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000242 DARBDN010000000
VERSION     DARBDN010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.252"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="SCH06_002965"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="SCH06_002965"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEG1079452.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          132 c          182 g          360 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt t
//
LOCUS       DARBDN010000243         1045 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000243 DARBDN010000000
VERSION     DARBDN010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.253"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>1045
                     /locus_tag="SCH06_002966"
     CDS             <1..>1045
                     /locus_tag="SCH06_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEG1079453.1"
                     /translation="IVINEGIIEKVENNWNYSDLLNENTELIAYDDQFVMPAIHDNHV
                     FFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKADEPIYAHGWDAALWKTDPSEEL
                     LNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKETSAESRVLLIKEMLANKKLLAE
                     VYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKILSNLYVQAVQEPLQHELLYEYK
                     EKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVASPEIDYEAIKAEVAAFNEVEI
                     PCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDLEMVTQKTAEKMNEGQVVAEVY
                     PQILGLNQTLEEAY"
BASE COUNT          357 a          159 c          237 g          292 t
ORIGIN      
        1 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
       61 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
      121 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
      181 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
      241 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
      301 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
      361 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
      421 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
      481 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
      541 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
      601 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
      661 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
      721 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
      781 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
      841 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
      901 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
      961 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     1021 aatcaaacgt tagaagaggc ttaca
//
LOCUS       DARBDN010000244         1019 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000244 DARBDN010000000
VERSION     DARBDN010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.254"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..573)
                     /locus_tag="SCH06_002967"
     CDS             complement(<1..573)
                     /locus_tag="SCH06_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HEG1079454.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSII"
     gene            complement(566..>1019)
                     /locus_tag="SCH06_002968"
     CDS             complement(566..>1019)
                     /locus_tag="SCH06_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEG1079455.1"
                     /translation="KLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNF
                     KIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPS
                     MNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
BASE COUNT          377 a          159 c          123 g          360 t
ORIGIN      
        1 aataatagaa gtatatccaa acatagctcc aacatttgga cttgtataga caccaaataa
       61 ccgatgttca ataaaacctt gtcttgcaag taatcctggc gttcctgttg ggacatgata
      121 agaaatcaaa aaaataaatt gatagataga tattagcgca gctaaaaaaa ttatgataat
      181 gaaaacatta ttaaaataca ccattttttt ctttttttcc tcttcacttt gtgaaaagtc
      241 tgcaggaaaa attactatca aagtaatcag caaatatcca aaattataaa tagatggaat
      301 taaaaaattt tctctgttaa tgattatagt taagataaaa ctaatcattg ctccaatcag
      361 tagccaagaa aaacgcattt taaaaaaatt tttctttata aaaacctcat acaaaactat
      421 aattccaccc caagcaaaag ctattttcat cgggatatta gttacattaa aagtactagg
      481 cataaaataa agcagacaaa tgattaaatt tattactcga aacgcatctc gacttaataa
      541 actcttctct aaaacaggta ctattctatt catctatatt tccaactttc aaaatttctt
      601 tatcaattct atttaatagt ttatcagagt aatccgattt aacttttctt acaaataatt
      661 tttcactttc ttttatttga tctatatccc tttcatcaaa ccatttgttc atggaaggat
      721 caataatatg aatatttgct aatttcgaag tttgtaaagt agtttcttca atatttttca
      781 attcaagtgg taaatctggt cctccaataa catttttatt tttgaacgag gaattaaaaa
      841 aaagtgtatg aaaaaatttt tcatctgggg caaacatacc tattttaaaa ttcaggtagt
      901 cttgttgatt ttgttcatac atttgtatta attctgttag gcattctttc gacaaagccc
      961 accattgaga accatgatac aaatcaaatt tatggtgtct aatttttggg ggaagttta
//
LOCUS       DARBDN010000245          995 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.256, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000245 DARBDN010000000
VERSION     DARBDN010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.256"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(26..913)
                     /locus_tag="SCH06_002969"
     CDS             complement(26..913)
                     /locus_tag="SCH06_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEG1079456.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          288 a          207 c          179 g          321 t
ORIGIN      
        1 taatttcttt gcctttttat ctaaatcaaa cgtttagttc ttgaccaact aataaagaat
       61 aactggacat agacatgcca tttttcgcca ttagatcatc aacagacatg ccaaattttt
      121 gtgcaatatc ccatagcgta tcacctgaca cgactgtata tgtctgacca ttatttgtat
      181 ttacatctgt tgttgaagat gatgacgttg aagtcgtcgt agtagtcgtt gttgttgtac
      241 ttgtggttgt tgtagccgaa cctgttgatg gcgtatcaaa acgggttaaa ttataagtat
      301 taatcaatga gttcaatttg gccccataat ttggatcggt agcataacga cctgtcaagt
      361 acgctgttgc atcataaaaa cttgttgtat tgcttttcca cacgccagca taatgataat
      421 cgcccgtgga aaaactggtt gaacgaagaa cattcgcatg gtcttggaag gattcccaat
      481 aagaagaata ttttcggaat ggctcattca tcgttaccca ttgtccgttt acatattctt
      541 tggttgccat ataaacgacc tgtccgttat agcttccttt cacaccgaat agattataat
      601 ttggcgcact agctaatccg gaagtgccat atgcactttc caacaacgct tgagcgatca
      661 tgactgaagc atacaagtca ttacttgcag caacttctga cgcagaccag ccgatttgat
      721 cgataaacgc ttgaggatca gcgactgttt gagatccttg ttcatctgca tgaacatgtt
      781 gcggtaccgc tgtaaccatc atcggcccaa ctaaaagact cgttccaatt aaaggagcaa
      841 tcgctttttt attgatcacc atttttcttt taggtctatg gtgccgggca ctgcgggtct
      901 tcagctcttg cattcaaatt cctcctcaaa ataaaaaaac ttaataaaaa gttctcttct
      961 taaaacaaac ttaattaatt aaattatact tttaa
//
LOCUS       DARBDN010000246          994 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000246 DARBDN010000000
VERSION     DARBDN010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.257"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..>994)
                     /locus_tag="SCH06_002970"
     rRNA            complement(<1..>994)
                     /locus_tag="SCH06_002970"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DARBDN010000247          986 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000247 DARBDN010000000
VERSION     DARBDN010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.258"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..704
                     /locus_tag="SCH06_002971"
     CDS             <1..704
                     /locus_tag="SCH06_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEG1079457.1"
                     /translation="YSVIFMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAP
                     TESAYIWKEVLQDLRKRGLEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIA
                     HKVRVRGRKEICEDFKLVYQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFY
                     NFPHAIRRTIYSTNLIEGFNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRI
                     HKGFKEIQDTLESMI"
BASE COUNT          333 a          161 c          163 g          329 t
ORIGIN      
        1 attattccgt tatatttatg gatgcgacgc atatccctgt gaagcgacag actgtttcga
       61 aggaagcagt gtatattacg attggtattc gtttggatgg aaccaaagaa gttcttgggt
      121 ttactattgc cccaactgag tctgcttata tttggaaaga agttcttcaa gatcttagaa
      181 aacgtgggtt agaagaagtt ttattagtag tgacagacgg attaagctgt attgaagaaa
      241 gtatccatag tgtgtatccg aatgcccaat ttcaacaatg ttgtgtgcat gtatctagaa
      301 atatcgctca taaagttcgt gttcgaggtc gaaaagaaat ttgtgaggat ttcaaattgg
      361 tttaccaagc gaattcaaaa gaagaggcat tggatcacat cgactttatg actaggaaat
      421 ggaaaaagca gtatccaaga gtcgtcaatt tactcttgaa tcctgcccta ttaacctttt
      481 ataatttccc tcacgccatc agacgaacaa tttattcgac gaacctgatt gaaggcttta
      541 ataagcagct aaaacgatat actcgaagaa aagaacaatt ccctaatgaa gaatctctag
      601 agagattctt catttctcaa tttaatcaat ataaccaaaa atttttaggt agaattcaca
      661 agggatttaa agaaattcag gatacattag agtcgatgat ttaactgtaa ttaacagaat
      721 ggattttcca tttacatata attcttgacg ctaccataat ctaaataacc atcatattca
      781 tctactactt atataattga gttttattaa actttttaag tttctattct atcaaatatt
      841 taaacaatct ctgcatccga aaagactacc tcgtatagtt ttactaacaa tatttttatt
      901 agcgtgttca aatcctgatt tcttgtatca attattttct gttcactttc aataagaaaa
      961 aagtctttac ttccatggat aataat
//
LOCUS       DARBDN010000248          986 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000248 DARBDN010000000
VERSION     DARBDN010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.259"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(200..748)
                     /gene="aac(6')"
                     /locus_tag="SCH06_002972"
     CDS             complement(200..748)
                     /gene="aac(6')"
                     /locus_tag="SCH06_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEG1079458.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          288 a          207 c          145 g          346 t
ORIGIN      
        1 caaaaatgta gaaagccatt ttcacaaaat ttttcttact actcgaaact aagcgacttt
       61 ttcacaacct ctggtacacg gtgttccaaa agtagcttct tcggaaataa gttggaattt
      121 cacaaaaatt caagaagtaa ttttcgtaaa ttccttctta tttcttgaag ctgattactt
      181 ctgtcacaac ctctttttat tattgagaat ttggtcgagg aataatcgtt tttgccatcc
      241 aaatatccgg tttgtcccag ccatttgcat ttggtaagac acctacgatt ttataaccta
      301 atttttcata gaattcatac ggatgttcac gaaggttctg gatggaagcc actttatcaa
      361 atgtatgctc atacaggtcc gtttgactta acgttgttcc atggtctaaa tcatccgtac
      421 ctaaataaat cgtgattcct cctctggaag ctacttcttt ttctaagtaa ttgactaatc
      481 gagtacctat ttggttcttt cgtcgggagc tttctacaac taatggatgc aattcccaac
      541 ctgtgatacc gtattgaggg attgcaccaa taaatcctac taactcatct tggtctaccg
      601 ctgctaccgc gattcgttct ggattcatca tttcttctac ttcttctgcc gagctgtctc
      661 catattcttc cggccaagtc agtctcagta aatcagaaag ctgatctttc aatactggat
      721 tattacggtc aaattcactg attatcatac gtcttccccc ttgttcttgc ttattctaac
      781 agtccttttg aaaaaacgaa atgttctcgc tcaaaaatct ttagctacca atcagtatct
      841 ctattctttc attatttatc ttacttataa aataaaaaaa ttatacagaa acactttatt
      901 caaaatagga aagatcagga aagccatcaa ttggaggaaa aaactctgtt tgttcatcat
      961 gatatagatt atcttttgct ttaaaa
//
LOCUS       DARBDN010000249          951 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000249 DARBDN010000000
VERSION     DARBDN010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.261"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            86..355
                     /locus_tag="SCH06_002973"
     CDS             86..355
                     /locus_tag="SCH06_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEG1079459.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            348..605
                     /locus_tag="SCH06_002974"
     CDS             348..605
                     /locus_tag="SCH06_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEG1079460.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          361 a          101 c          177 g          312 t
ORIGIN      
        1 ataagaagtt agaatattaa tcatttgctt aattgtacaa tataatgtac aattgtttta
       61 tagaaataaa taaggggtga aaggaatgga agcagtagct tattcaaatt tccgccaaaa
      121 tttacgtagt tatatgaaac aagttaatga ggatgctgaa acacttattg taacaagtaa
      181 agatgtagaa gatacagttg ttgtattatc aaaaagagat tatgattcta tgcaagaaac
      241 gttgagaaca ctttctaata attacgtcat ggaaaaaatt cgtcgaggag atgaacaatt
      301 ctccaaaggt gcatttaaaa cacatgactt aatcgaggtt gaatctgatg attaaggctt
      361 ggtctgatga tgcttgggat gattatcttt attggcatga gcaaggaaac aaaagcaata
      421 taaaaaagat taacaagtta ataaaagata tcgatcgttc cccctttgct ggattaggaa
      481 aacctgagcc attaaagcat gatttatctg gaaaatggtc cagaagaatt acagatgaac
      541 atagactgat atatagagtt gaaaatgaaa cgatatttat ttattctgca aaagatcact
      601 attaaccaat cggaagtaag gaaagggtca gaaacttaaa agtttttgat ccttatttta
      661 tttaccctag tcatttaaaa agctaatata gcttagtgtt gattgttatt aatgaatgtg
      721 tttgttacgc gtattacgga tataaggtta gtaaaatcat ttctaaagtt gaggaaaagt
      781 aaatataaat ggcttaaatt tcaacaattt gaagttgaat agatatgtta taatactatt
      841 gtagtgtggg atgttagtta ctaaaggatg acgcttatat atatgactga atagaataag
      901 caataggttt aataatctat tttaaatttt ttgtactagt tttagttaat t
//
LOCUS       DARBDN010000250          949 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000250 DARBDN010000000
VERSION     DARBDN010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.262"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>949
                     /locus_tag="SCH06_002975"
     CDS             <1..>949
                     /locus_tag="SCH06_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEG1079461.1"
                     /translation="FLIQFAKGLEKVKAMGIAGIISTIVTIIANIFFLLILKWGLIGF
                     FIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPLIATVVGWWINSTA
                     DRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKEYGDNETAKFYGNT
                     FVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIANVLNCASGLLGPIL
                     SAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSYVIYVVRKRAVGKD
                     IFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIMIIL"
BASE COUNT          306 a          114 c          179 g          350 t
ORIGIN      
        1 aatttctaat acaatttgct aaagggttag aaaaagttaa agctatgggc atagcaggta
       61 ttatcagcac aattgtaaca ataattgcca atattttctt cttgcttatt ctgaaatggg
      121 gattaattgg ttttttcatt gcaaatattt tatcacagat tatttcagct acttatctgt
      181 cagtattagt gagaatatgg gaatatatcg attttgaggc taaagatcct cagctaaaga
      241 gagaaatgct aaattactcg attccattaa ttgcaactgt tgttggatgg tggattaata
      301 gtacagctga taggtatgtg gtttccttta tagtaggtgt ctcggcgaat ggcttattgt
      361 ctgtggcata taaaatacct caaataatta atactttgca gggaatattt atacaggcct
      421 ggcaaatttc tgcaattaaa gaatatggag ataatgagac tgcaaaattt tatggaaata
      481 catttgttat gattaatttg ttaatgtgca taacctgttc aagtcttatc atattaacta
      541 gaccgttttc acatattctt tatgcgaaag acttttatga agcgtggaaa tatgttccat
      601 ttttattaat agctaatgtt ttaaattgtg catcaggtct gttaggacct atcttatcag
      661 caaaaaaaga ttctaaatcc atgatgtggt ctgcaatcat aggggcatta gttaatgtga
      721 ttatgagtgt agtccttgtt tataagatag gggttcaagg tgccacaata gccactgtta
      781 tatgttcata tgtaatatat gttgttcgta aacgagctgt gggaaaagat atttttataa
      841 agcattatca tattgttgtg gaatcttggg gattattgtt tgttcaggca atcatagaaa
      901 tatattttaa aaattatgta atagaaatta taattatgat tattttaat
//
LOCUS       DARBDN010000251          948 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000251 DARBDN010000000
VERSION     DARBDN010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.263"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..948
                     /locus_tag="SCH06_002976"
                     /pseudo
     CDS             1..948
                     /locus_tag="SCH06_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          351 a          162 c          180 g          255 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataaagatg ccgttctagt aaaaaaagca tttagccgta
      661 tcaaacaacc tctgacagag gttgagattt ttcatactga tcgtggaaaa gagtttgata
      721 accaagctat tgatgaatta ttaacaactt ttgacatcaa tcgatcattg agtcataaag
      781 gctgtccttt tgataatgcc gtagctgaat caacttataa gtcgttgaaa gtagaatttg
      841 tctatcaata cacatttgaa accttacaac aattggattt ggagttattt gactatgtca
      901 attggtggaa ccaccttcgg ttgcacggta cacttggcta cgagacac
//
LOCUS       DARBDN010000252          939 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.264, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000252 DARBDN010000000
VERSION     DARBDN010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.264"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            306..939
                     /locus_tag="SCH06_002977"
                     /pseudo
     CDS             306..939
                     /locus_tag="SCH06_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          314 a          177 c          174 g          274 t
ORIGIN      
        1 cttcaattat ctaaatctcg aaaatggtta gatgtaatca tcaggaaaaa caatcttaaa
       61 cgaattacta ttcatggtct tagacacaca catgctagct tgcttttagc aagctagtgc
      121 aaatattaaa gatgtgcaag agcgtttagg ccactcttct attcaaatca ttatggatct
      181 atatattcat attacagaca aaagaaaaga agaaaccgta gcgcaattcg caaaatatag
      241 gctctataat ttatgggact gatgaatcaa aattgattct tcagtcccat tgttatttta
      301 ggtatatgat tcgtacattg aaagagttga aaaactatct tccgaagccg tcaaaaagga
      361 ccctgccaaa agtattgatg gtggatgaat ttcgttcgca cgcttcaatt gtggataaaa
      421 tgagctttat ttgtgcggat ggcgagactg gaaaactcat tgatattttg cctacacgaa
      481 aattgtctcg attaacacac tattttagtc gctgtgcaaa tcctgaagcg gtggaatatt
      541 tagtgacaga tatgaacgcc gcctacttcc aactgacaaa acgtgtctta ccaaatgcga
      601 aagtcgtcat tgattgtttt catatcatca aacatttgaa tcaggcgttc aatgattttc
      661 gtgtacaaga aatgaaaaga ttacaccagt tagggcaacg acgggaagcc gagaaagtga
      721 aaaagaactg gcgctttctt ctaaaaaacc gtcaaaaaat caatcactat gattacaaaa
      781 catggcgcag ttttcgtgca cctaaatacc cgctactcac tgaagcaatg atgattgatc
      841 gattgctggc attttcaacg cctttaaagg acgcctatac ttttttccat gagctgaccg
      901 aagcctttag agacaaggaa tcagacttat tttttacct
//
LOCUS       DARBDN010000253          927 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.265, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000253 DARBDN010000000
VERSION     DARBDN010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.265"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..788
                     /locus_tag="SCH06_002978"
     CDS             <1..788
                     /locus_tag="SCH06_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079462.1"
                     /translation="ALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKYYI
                     SLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLSR
                     RALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHK
                     DGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          341 a          146 c          168 g          272 t
ORIGIN      
        1 ttgctttgat tgatagtaaa ttcatcaaag ttcctaaatt gaagtcatta gtaagaatta
       61 agcttcatag acaaccaaaa gggattatca aatccgctac aatatcacgt cattctagcg
      121 gtaaatacta tatttctttg ttgtgtaaag aagaaattat cgaattacct aaaactaatt
      181 ccacaattgg tattgactta ggtattatgg actttgcgat tctttctgat ggacaaaaaa
      241 ttgataataa taaattcacg tccaaaatgg aaaagaaact aaagcgtgaa caacgcaaat
      301 tgtctaggcg tgctttattg gctaaaaata aaggtaccaa tctatttgaa gctaaaaatt
      361 atcaaaaaca aaaacgcaaa gtagctagat tgcatgaaaa agtaatgaat caacgtactg
      421 attttctgaa taagttgagt acagaaatga tcaaaaatca cgatattatc tgtattgaag
      481 acttaaacac aaaaggtatg ttgcgaaatc ataaattagc taaaagtatt tctgatgttt
      541 cttggtcaaa gtttgtgact aaattacaat acaaggctga ctggtatgga cgaaaaatca
      601 tcaaagtaga taaatggttt ccgtctagtc agatttgttc agagtgcgga cataaagatg
      661 gcaagaaatc tcttgaaatt cgagaatgga cttgtcctgt ttgtcatact catcatgatc
      721 gtgatatcaa tgctagtatc aatattctga ccgaaggtct aagactacat tctatgggat
      781 tggcttagat ccaatcatca agaaccgtag gaactacggg gatagcttgg taaataagag
      841 acaccgctgt tagtaaagaa atacgctatc aagtatgctc tattcccaag aagctcccac
      901 ttcaagcgtt aagaaccgtc aggttta
//
LOCUS       DARBDN010000254          903 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.266, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000254 DARBDN010000000
VERSION     DARBDN010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.266"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            263..886
                     /locus_tag="SCH06_002979"
     CDS             263..886
                     /locus_tag="SCH06_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEG1079463.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          333 a          129 c          167 g          274 t
ORIGIN      
        1 gttttaaaat aaactaatgt ccttattttt gtgttcacat ttctgttacc taagaaatac
       61 ttaaaggagg tgatgtagcc agcaacgact acaacttgaa cccgctatct acagtttatt
      121 tgttgtttct tttgggtata ctctaatggt acaaatccat atttgcttaa agcgttgatt
      181 tttcagcggt ttttctttat tgcaaagtgt accctaagac ctgtatacta atagtaaata
      241 gattggatag gaatgatggc aaatgtattt agcttattta agagtttctt ccgacgatca
      301 aagtttagct cggcaacata agctaattga aaattggtca gtcaaaaata atattgctga
      361 agacgattta aaaattttcg aggaaaaagt ctctggaaaa aatattgaaa acagaccaga
      421 gctgcaagag cttatttctt tcatacgtga acgagatacg attattattc ctagtcttga
      481 tcgattagca agaaatagta aagatacaaa agacttactt caattgtttc gtagtaaagg
      541 tgcttctatt gaaatattag acctaccgtc gtttaatggg gtaactgacc ctgcattaag
      601 agacttgcta acaaatttag tcatagaagt gtttagctat gttgctgaaa acgaacggaa
      661 aaaaatcaaa gagcgtcaaa aacaaggcat tgaaattgca aagaaaaatg gtcgttatac
      721 tggtaaaaag attcaatacc atgccaatgc aacaggaaaa aacaaattga tttacgatga
      781 aattgttgat ggtctgaaga aaaaagaaac tatttctaaa atagcaaaga acgcaggagt
      841 tacaagaaaa accgtttatc gagtaaaaag agatttagga atgtaatatg ttccagttag
      901 aaa
//
LOCUS       DARBDN010000255          897 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.267, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000255 DARBDN010000000
VERSION     DARBDN010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.267"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(91..>897)
                     /locus_tag="SCH06_002980"
     CDS             complement(91..>897)
                     /locus_tag="SCH06_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HEG1079464.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIVTDL
                     TYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          236 a          211 c          173 g          277 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggtttgg ttatcaaatt cctttccccg
      421 gtctgtatga aaaagcttga cgtctgttaa agaatacggt atccgtccaa aggcttcttt
      481 taccaatgag gcatctttct tctcaccaca ggaataacca ataatttctc gattaaacaa
      541 atcaagtatt aagcagatat aatgccactt tttccccacg cgaacataag taagatccgt
      601 aacgatggct tccaatggct gttcttgtgt aaaggtccga tctaatacat tcgctgtttt
      661 cgcttcatta caagctgttc gttgcccttt aaaatgagcg atcgtatagg tagatgtcaa
      721 tccgcggcgt ttcatgattc gaccgattcg gcgccgactg agttgaagcc cacgctttgc
      781 taaacacttc ttcaattttc gggtaccgta agcctttcgg tttcgaataa actcttcctg
      841 aacgatctct tctaagtcgg actcattttc gatcggtttc gcttgataat agtaggt
//
LOCUS       DARBDN010000256          888 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.268, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000256 DARBDN010000000
VERSION     DARBDN010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.268"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..358
                     /locus_tag="SCH06_002981"
     CDS             <1..358
                     /locus_tag="SCH06_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEG1079465.1"
                     /translation="FFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRRFPEGEE
                     VWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDDWQKVMA
                     AEVIATYLDGDLVYKK"
     gene            406..>888
                     /locus_tag="SCH06_002982"
     CDS             406..>888
                     /locus_tag="SCH06_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEG1079466.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     D"
BASE COUNT          260 a          148 c          206 g          274 t
ORIGIN      
        1 cttctttaat tattgtcgat tagaggaaag tggtgtaaca gtcactagcg gtacagattt
       61 accgctgttt attactgata ttcctgaatc gattataaga gcagtattcc gtcgttttcc
      121 tgaaggagaa gaagtctggg agaaagaaac aagcttcacg acaaccgagc tgctgaaaag
      181 ttttacaagc aacagcttca aagtaaatgg tttatcggag tacggagaaa taaaagtagg
      241 gaaaagcgcc agcttagctg ttttcagcga ggacctctgt actgatgact ggcaaaaagt
      301 gatggctgcg gaagttatcg ctacctatct tgatggtgac ttagtttaca agaaataatg
      361 cttttcgata taacgttata agacgaatta aagagaggtt aaaaaatgga aacaatgaaa
      421 agaaaattca ccttcccaca tagttataca ttgattttta tcttaattat tttggctgca
      481 attttaactt ggataattcc tagtggtcag tttgagacag ttgttgaaaa cgtcgcaggt
      541 atggaaaaaa caacggttgt tccgggaacc tatcaccaaa tcgataaggc agattatgga
      601 caaggttttt cctctatact aatggcacca gctgaaggga ttatttcagc tgttgaggtt
      661 gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta tcctaaaaac gggagccatc
      721 gatcgagggc tgtttacctt agcaaaagtt ctgggagaca aggggatctt agttattccg
      781 atgtcgatga ttctattcag cttaggagga tcaacctttg gcatgagcga ggaagtcatt
      841 cccttatttg cggtgtttat ttctctgatg ttttctcttg gctatgat
//
LOCUS       DARBDN010000257          818 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.269, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000257 DARBDN010000000
VERSION     DARBDN010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.269"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            136..309
                     /locus_tag="SCH06_002983"
     CDS             136..309
                     /locus_tag="SCH06_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079467.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
BASE COUNT          275 a          131 c          103 g          309 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaat
//
LOCUS       DARBDN010000258          813 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.270, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000258 DARBDN010000000
VERSION     DARBDN010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.270"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            389..787
                     /gene="spxA"
                     /locus_tag="SCH06_002984"
     CDS             389..787
                     /gene="spxA"
                     /locus_tag="SCH06_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEG1079468.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          310 a          110 c          143 g          250 t
ORIGIN      
        1 taacagagaa aataagcgtt ataataaaga acagtattat ttaaaatgac agaaaacatt
       61 actattaaag aaataaaaaa cataaaaaat cttaagaaat cggtttcatt tagcttttga
      121 gataaaataa tagtacagtt ttatacgctg tttcatatgt ttagaaaatt tgaattagat
      181 ttgaaaactc taatttttaa atgataaaaa aagcgagaat gctggtttta ctgtatatta
      241 accttagata actttcattt ttttaaaaaa attatgaaaa aaaggtagct atttaaaagt
      301 tgattatgta taatagaaac agatgggaga ttattatgat cttctgttac aaaaaagtga
      361 ttcttatcac gaaaaggagt ggtgcacgtt gttaacatta tatacttccc caagttgtac
      421 ttcctgcaga aaggctcgtg cgtggttgca agaacatcag attccatttg ttgaacgtaa
      481 tattttttca gaaccattga acagttctga attaaaagcg attttacaaa tgacagaaga
      541 cggaacagaa gaaatcatct cgacacgttc caaagtattc caaaaactga acatggattt
      601 agatgatctg ccgttacaag aattattgga acttgtgcaa aacaatcctg gattgcttcg
      661 ccgtccaatc atgattgatg ataaacgtct gcaagttggt tttaatgaag atgaaattcg
      721 tcggttccta ccgcgcgatg tacgacaatt agaattacgt caagcacaat tgatggctgg
      781 attatagaag gataatacga aacttggaaa aga
//
LOCUS       DARBDN010000259          803 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.271, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000259 DARBDN010000000
VERSION     DARBDN010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.271"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            129..>803
                     /locus_tag="SCH06_002985"
     CDS             129..>803
                     /locus_tag="SCH06_002985"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079469.1"
                     /translation="MSMNHFIKQLFTIKDSNIQIQSFEETFYKSRKSIVIEGTLIRTY
                     RRCPCCKDSTKQIVKNGKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLV
                     TPFCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPR
                     CLLFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHY
                     IVTDMNA"
BASE COUNT          240 a          155 c          147 g          261 t
ORIGIN      
        1 gctctataat ttctaggact gatggaaatt ttctatctgt cctagttttt ttgtaaaaaa
       61 acaaaaagac atacaaaatt tccggtagaa tagagtctcc tacaacatca ttctggggga
      121 attcttgtat gtccatgaat cattttatca aacaactctt tactattaaa gactcaaata
      181 tccaaattca atcctttgaa gaaacttttt ataaaagcag aaaaagtatc gttattgagg
      241 gaactctgat ccgtacctac agacgttgtc cgtgttgtaa agattctaca aagcaaatcg
      301 ttaaaaatgg caagaagatc tctatgattc tcctgaatcg tagcggtaat aaacggacct
      361 atcttcggtt gaagaaacag cgatacctct gccgagcatg taaaaaatat tttaccgctc
      421 ggacgtatct cgttacccca ttctgcttta tttctaagca gattcattac aagatcttag
      481 aagaattgac agagcgtcaa tctataaaag caattggtaa acattgcgat gtttctgtga
      541 caactgttca gcggacattg tccgccttgt catcagatat ccgtcagaat cttgagtatt
      601 tacctcggtg tctattattc gatgagtttc gttctctttc tacatggcac ggtaaatttt
      661 ctttttcttg tatggacggt gagaccggga aactgtttga gatcttacct agccgccgta
      721 aaaaagatct cgttgctttt ttcatgcgtt tttctctcaa agcgaggttg ggtgtacatt
      781 acatcgtaac ggatatgaac gct
//
LOCUS       DARBDN010000260          790 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.272, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000260 DARBDN010000000
VERSION     DARBDN010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.272"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..395
                     /locus_tag="SCH06_002986"
     CDS             <1..395
                     /locus_tag="SCH06_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079470.1"
                     /translation="ISLKDESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQE
                     YYFYKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKI
                     GVINFKNKYQIKGIKLNQKTIKKLNIGG"
     gene            398..>790
                     /locus_tag="SCH06_002987"
     CDS             398..>790
                     /locus_tag="SCH06_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079471.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIREL"
BASE COUNT          319 a          128 c          146 g          197 t
ORIGIN      
        1 aaataagcct caaagacgaa tcgaatacaa ccgtgagtga tgccaatatc ttagcgaata
       61 tcatcctaga tttcatcttt gaacatcata ttcctttcaa agaaggatat gagattttac
      121 cagcgaatca agagtattac ttctacaaat gcattacaaa aagagtctgc tgcatctgtg
      181 gcaaaacagg agctgacatc gatcactttg acaaagcgct aggaagacga aagcgcaaag
      241 aagttgatca tgcagagtac acatttgcag cactctgcag aatccatcac acagagaagc
      301 acaaaatagg tgtgattaat ttcaaaaata aatatcaaat caaagggatc aaattaaacc
      361 agaaaacaat caaaaagtta aatattggag ggtaaaaatg acagaacatc gaagttatta
      421 tgcgattata ccagccaacg taaggtacga caaaagactt aaaccaaata ctaagttgtt
      481 atacggagag ataacggcct tgtgtaatga aagaggcttt tgttgggcag gcaatgagta
      541 ctttgcagat ttatatggtg tgaataaaga gaccatatcg cgatgggtaa gtgatttgat
      601 taagtttgga tacttgaatc gggaaatcat ttacaaagag ggtaccaatc aaataatcaa
      661 taggtaccta cgaattaatc aataccctat tgacgaaaaa cgcaataccc ctattgacga
      721 aaaagtcaaa gataataata catctattaa taatacattt aataatacaa aagaatatat
      781 aagagagtta
//
LOCUS       DARBDN010000261          746 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.273, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000261 DARBDN010000000
VERSION     DARBDN010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.273"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            129..515
                     /locus_tag="SCH06_002988"
     CDS             129..515
                     /locus_tag="SCH06_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079472.1"
                     /translation="MKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRFEVLKIQKNE
                     LLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYV
                     EDEDIIKYMKPVIKLVNKNKGTRGAS"
     gene            609..>746
                     /locus_tag="SCH06_002989"
     CDS             609..>746
                     /locus_tag="SCH06_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEG1079473.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT          301 a           95 c          135 g          215 t
ORIGIN      
        1 aaggaaatat gaatattaca agtaacaaaa cgtcacgtgt gctattggcg ttgatgggtt
       61 acggaattct ttatagagat gaccaaaatg gccagattct aataactcgg gctgggcgtt
      121 cattattaat gaaatataga aaatttatac cggaagattt tcaaaactta cagttagaaa
      181 acatgcgttt agaagattta tttagattag cagaagatga taagtataga tttgaagttt
      241 tgaaaattca aaagaatgaa ctattgaata agttatatcc tgagaatgcg ataaaagcac
      301 attttggtga tgctaatcat atgtatagtt ggttcattcc taaaagattt agagggaaaa
      361 tcaatgctgg agatcaagtg aaagtactca atcgaaatag tacagatgtc gtaatgataa
      421 cagatatcta tgtagaagat gaagatataa tcaaatatat gaagcctgtg ataaaacttg
      481 ttaataaaaa taaaggaacc cgtggtgcta gttaattttt tcctagagga aaatgtctaa
      541 acatgttagt aaatcaacaa aaaaacgcat atagtagtct caaaactccc aagaaatgag
      601 gactacatat gcgttcatca aaatatactg aacattatac agatactttt ataacattca
      661 aggaaattat gagaactgtt tctaacatat accacaattg tgtaccagat aagattaaaa
      721 accgaagaaa tactgatcaa ctgaag
//
LOCUS       DARBDN010000262          733 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.274, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000262 DARBDN010000000
VERSION     DARBDN010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.274"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>733
                     /locus_tag="SCH06_002990"
     rRNA            <1..>733
                     /locus_tag="SCH06_002990"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          226 a          146 c          216 g          145 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga att
//
LOCUS       DARBDN010000263          722 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.275, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000263 DARBDN010000000
VERSION     DARBDN010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.275"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(47..406)
                     /locus_tag="SCH06_002991"
                     /pseudo
     CDS             complement(47..406)
                     /locus_tag="SCH06_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          208 a          132 c          148 g          234 t
ORIGIN      
        1 ggagtggaga aatccactct ttttttcatg ctctaaaatg atatttttac acaaccgtaa
       61 cggttgtttt acgaaattgg acgggacttt gccagtttaa tttctgtttt atccgttcat
      121 tattgtagta atagatatag ctatcgatgg ctgattttaa ttcctcgaaa cagttataaa
      181 ctttcccgtg aaaaatctct tgttttaata agccaaaaaa attctccata agtgaattat
      241 ctaagcagtt ccctttccga gacatgcttt gaaagatttt gtactccttc aatttgtttc
      301 tataagcttt catttgatac gaccaacctt gatctgagtg aaacgtacga cgatagggac
      361 aatcgttagt ggtctggata gcttcctcca aaccttccat taccgcacgt gtttctgaat
      421 ggtggtagcg accgatttga acggctaggg cggaaatacg gtgcaaatgc acggtggttt
      481 catgcaatgc ttacagggcg tattttgtaa gggtatgtaa cggagataat cccgacggta
      541 atggatgtga gaggccaagc cgacgctgac ggtagggcaa acaaacatag ttgcactcta
      601 gcgatcgtta tttattttta acggtcaaac tagggtacaa ctatgcttaa aacacttcgc
      661 ctcaacttct ggtagcaaaa gtgattttga aagtcaaaat attttttatg agttatttat
      721 aa
//
LOCUS       DARBDN010000264          712 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.276, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000264 DARBDN010000000
VERSION     DARBDN010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.276"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..446)
                     /locus_tag="SCH06_002992"
     CDS             complement(<1..446)
                     /locus_tag="SCH06_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079474.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          216 a          123 c           95 g          278 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttatta ataaaatggt atattttata ttgttataaa aagagcccaa cc
//
LOCUS       DARBDN010000265          710 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.277, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000265 DARBDN010000000
VERSION     DARBDN010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.277"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            13..486
                     /locus_tag="SCH06_002993"
     CDS             13..486
                     /locus_tag="SCH06_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HEG1079475.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            495..>710
                     /locus_tag="SCH06_002994"
     CDS             495..>710
                     /locus_tag="SCH06_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1079476.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTI"
BASE COUNT          226 a          114 c          132 g          238 t
ORIGIN      
        1 agagggataa aaatgaaatt taaaacattg ctattaaaat ttgtcgtttt aggtataagt
       61 gccgtattta ttttgttcgg cgtacttttt tatactcaga tcgctacaag cgaaaaagga
      121 ttcaattttg attggcagac cacattattt gtttctgtca tttactttgc ccttctccta
      181 gggatcgtta ttgcttattt cttattgaaa ctattgaaaa aaatcgaaga taaccaagct
      241 ttttccactc aaagcttaaa catactaaaa aaaatcgaac gaaccatttt gtttattggt
      301 ttcgcctttt ttggcttact tcctaaattt atgaaagtag cggatttaga cgatgctcca
      361 ggtttgatgt tggtaggaat cgctgtcgta ttcattcctt ttgcagtata cacattaaca
      421 agcgtgctgg aaaaactgct tgaacatgcg attttactta agacagatca tgatttgaca
      481 gtgtgaggtg cgacatggca attatcgtta atttagatgt agtattagct caaaaaaaaa
      541 tgagtgtgac tgaattgagt gagaaagtgg gcattacgat ggcaaacatc tctattctaa
      601 aaaatggaaa agcaaaagcc atccgttttt ccactctcga aaaaatctgc caagttttgg
      661 agtgtcaacc aggtgatttg ttgacctata aaaatgactc gaatactata
//
LOCUS       DARBDN010000266          703 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.278, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000266 DARBDN010000000
VERSION     DARBDN010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.278"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          297 a          106 c          122 g          178 t
ORIGIN      
        1 attccttagg cagcttttgc tgtgtagaaa ggaataaata ataacgaaag ttcaaaagct
       61 aatgccgact attctagaca ttaaagaaga cgaaaacgaa cgataaagaa agaaaagtta
      121 tgaataatcg tttattgaaa aaaacttgaa aaaatacaaa aaattcgttg accaagctaa
      181 atttagttgg tatattatta cttgtccaaa agacagaaga aaatatttat tcaaaaacat
      241 aacaaaaaag ttattgacat gttactaacg acatgataag ataactgagt cgttaaaaaa
      301 gaaccacttg cgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa
      361 caaacgataa gttatgataa atgagttgcc gaaagatttc gaaaaacgaa atcgaaaaaa
      421 acttttaaaa aagagttgac aatcgcttgt ctctctgata tgatataaaa gttgctacgg
      481 cagccaaaaa tgaatcggga aacactctcg atgaagtaga cctttgaaaa ctgaacaaag
      541 taagacaaac caaatgtgta gggcgtcttg attcaattca agacaacaaa catttttaac
      601 aagcaagcaa tatgctagca aacaaattga gcttaacaat cgcaagattg ttcgaacttt
      661 ttatgagagt ttgatcctgg ctcaggacga acgctggcgg cgt
//
LOCUS       DARBDN010000267          694 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.279, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000267 DARBDN010000000
VERSION     DARBDN010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.279"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..303
                     /locus_tag="SCH06_002995"
     CDS             <1..303
                     /locus_tag="SCH06_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEG1079477.1"
                     /translation="FRVSESEFAKLKQSAEALQMSVPAFVKAKAQNARLVTPKVAPDI
                     AQAIARDLAKAGGNINQIAKWCNTHQHDVDPGDAQRLSENLKIMQKELQKIWQQLK"
     gene            285..>694
                     /locus_tag="SCH06_002996"
     CDS             285..>694
                     /locus_tag="SCH06_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEG1079478.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICL"
BASE COUNT          241 a          164 c          147 g          142 t
ORIGIN      
        1 tttcgagtga gcgaatccga atttgcaaag ctgaagcagt cagctgaagc tttgcaaatg
       61 agtgtgccgg ctttcgtgaa agccaaggca caaaacgcgc gtctggtgac accgaaagtg
      121 gcgccagaca ttgctcaggc aatcgcgcgc gatttagcca aagctggcgg gaatatcaat
      181 caaattgcca agtggtgcaa cacacaccaa cacgacgttg atcctggcga cgcccaacgc
      241 ttatccgaaa acctaaaaat catgcaaaag gagctacaaa agatatggca acagttaaag
      301 taagccgaac cacttcttgt agccgagcga tcaattacgc cgaaccacga gcaaccgtca
      361 aaacagggat aaactgtgac attgattatg ccaaaagcga aatgaaacaa attcgcatgc
      421 tgtatggaaa agacgatcgt gtacaagcac acttattgat ccagtctttt cgaccaggag
      481 aaattaccgc tgaaaaagcc aatcaactag gggcagagta tgcgaaaaaa atagcccctg
      541 accaccaaat cgcgatttac acacatacag acaaagacca tattcataac cacattgtca
      601 ttaactccgt caatctggaa actgggaaca aatttcaagc ccatggtcaa gcatttttaa
      661 acaaatgtta tgacctaaat gacgagattt gtct
//
LOCUS       DARBDN010000268          691 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.280, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000268 DARBDN010000000
VERSION     DARBDN010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.280"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..419)
                     /locus_tag="SCH06_002997"
     CDS             complement(<1..419)
                     /locus_tag="SCH06_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1079479.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDL"
     gene            complement(416..>691)
                     /locus_tag="SCH06_002998"
     CDS             complement(416..>691)
                     /locus_tag="SCH06_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEG1079480.1"
                     /translation="KDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLDNNGQVLTRMQ
                     IIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          209 a          108 c           53 g          321 t
ORIGIN      
        1 cttaaatctt tcgcatcttt ttgcatatca gctgtagaaa caaattgtag atttgttttt
       61 ttaccatcat taagctttat ttctctttct tcaattatca aagaattact atcactttct
      121 aaattaacat ttatattatc tttgatttgt atttcattct tattattttt ttcttttatg
      181 aatactttta tttcactact cttggaataa aactccaaag tttgttctat atattttatt
      241 tcttttccat tcatattact agaaatttca tttgccatat tatgaatctt ttcttttctc
      301 gtctccaaat atgttttagg aaagataaaa aaaattaatg aatgaactaa tataattatt
      361 attccaagaa cagaaaatat ttgtatgaac atttttggaa atatctttaa ttttttcatt
      421 ttctctccaa tttatatcct acatttctta tagtagttat acagtctaat tgtaattttt
      481 ttctaagttc ttttatatat acatctatta ctcgatcata aggagtttct tcgctatctt
      541 tccatacata atcaataatt tgcattcttg ttaacacttg tccattatta tccaataaac
      601 attttaatac ttctagttct tttgcattta catctatttc ttcaccattt attttagctg
      661 tatagctatt aaaattaacc gatagatcct t
//
LOCUS       DARBDN010000269          690 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.281, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000269 DARBDN010000000
VERSION     DARBDN010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.281"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            132..344
                     /locus_tag="SCH06_002999"
     CDS             132..344
                     /locus_tag="SCH06_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079481.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..>690
                     /locus_tag="SCH06_003000"
     CDS             506..>690
                     /locus_tag="SCH06_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HEG1079482.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVL"
BASE COUNT          245 a          103 c          121 g          221 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct
//
LOCUS       DARBDN010000270          651 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.282, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000270 DARBDN010000000
VERSION     DARBDN010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.282"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..575
                     /locus_tag="SCH06_003001"
                     /pseudo
     CDS             1..575
                     /locus_tag="SCH06_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347576.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT          265 a           73 c          102 g          211 t
ORIGIN      
        1 gctgtttggc acaggttatt ttccaattat ggattggagg aatatttctt attgatgtta
       61 ttttattagc taaaggaaca ataagtatta ctaattttgt aatagtattt atgtacgcta
      121 acatggtccc tactttatgg actactttaa ttagtattat ttggaaatgg caagactatt
      181 cagtgtcatt aaatagatat tacgaatatt attcaaataa caacaaagtg gctggcacaa
      241 aaaaaataaa taaaataaat tctattactg gtcaatcatt aaatttttca tataacaaaa
      301 gaaaggtatt aagcaatata agtttttcaa ctgaaatgaa taaactattc atgatatcag
      361 gagaaaatgg aacagggaaa acaacactga tgaaattatt tactaaacag ttgccggtta
      421 gtaataatca attattcgtc aacgggatag atattaatat gattgataac gaatcattaa
      481 gaaggttaat ttcaatcgca acacaaatac catatataat taatagctcc gtgaaggaga
      541 atattttaat ggggactaaa aactatgata aaaaaaaatt cagtaaatta atagaactat
      601 tgggaataag taaatttatg acgaaattag gtattacttt ggacgacaat a
//
LOCUS       DARBDN010000271          638 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.283, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000271 DARBDN010000000
VERSION     DARBDN010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.283"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          221 a           98 c          103 g          216 t
ORIGIN      
        1 gaagagtatt atacaagcta aagcttttct tcattgccac tcaaatgagt ggctttttta
       61 tgtatccttt tatggattaa tgaaaggatg tttcacatag ttatacttct gtatatttga
      121 aaagttttac tttgattttt aaatagaaag acatttgggt taaattgtga gataataata
      181 aagaagagtt taaagcgcac cccaaaccac ttccccataa gtgtgttacg ctttaaactc
      241 ttttatattt gaagccatta aaaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttacaattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
      361 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatctccttt
      421 cacaagtatg gtgataaaat tcgttccggg ctaccttttt aggtagccta ctttaatctt
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
      541 gtgcgtccgg cacgtcagtc atgaatcggc tacactagac tagacagaaa aaataaggtg
      601 tgtagaataa taaaaaacac actggaggat ttttcatg
//
LOCUS       DARBDN010000272          619 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.284, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000272 DARBDN010000000
VERSION     DARBDN010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.284"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..321
                     /locus_tag="SCH06_003002"
     CDS             <1..321
                     /locus_tag="SCH06_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HEG1079483.1"
                     /translation="FFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKF
                     YEVNPVLEEPVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFG
                     IHYD"
     gene            389..>619
                     /locus_tag="SCH06_003003"
     CDS             389..>619
                     /locus_tag="SCH06_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEG1079484.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHK"
BASE COUNT          216 a           93 c          143 g          167 t
ORIGIN      
        1 ttcttttcta tagaagactt ttccgatgaa gaagtaaagc agtttttgat gaagcatttt
       61 tgtgagcgaa atgatgtatt gattgcaacc cgaggagaaa aaacggctat tggttatgat
      121 ggagcaaagt tttatgaagt gaaccccgtg ctagaagaac cagttgatac aatggcagcg
      181 ggagattctt tcttaacagc tttcctactt tattttctcg aaggggacga tatagtcacc
      241 gcgatgaaaa aggggaatga atttgctggg aagtcttgtc tggttgacgg ttcgttcggc
      301 tttggtattc attacgattg agcttgtttt aaattcctgc atttgataac ctaaagaaag
      361 aaatcccggt aaagtggagg ttaaaaaaat gctggataca aatgcacaat taccattgta
      421 cttacaatta aaagaaatat taaaaaataa aatcaataca ggggagtatc ccgagaatac
      481 gaaaattccc gctgaatcag agctgataga aagttatgag gtcagccgaa tcacagtgag
      541 aaaagcagta gaagaactgg tagaagaagg gtacctactt aaaaaacaag ggaaaggaac
      601 ttttgtcaac cggcataaa
//
LOCUS       DARBDN010000273          606 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.285, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000273 DARBDN010000000
VERSION     DARBDN010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.285"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            7..>606
                     /locus_tag="SCH06_003004"
     CDS             7..>606
                     /locus_tag="SCH06_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079485.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCG"
BASE COUNT          218 a           83 c          115 g          190 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggt
//
LOCUS       DARBDN010000274          606 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.286, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000274 DARBDN010000000
VERSION     DARBDN010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.286"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          236 a           78 c           77 g          215 t
ORIGIN      
        1 gaaaatacat tagcaatata taaaagaagg tatcaagagt cacagtgaat ttattccgaa
       61 aagtgaaaag agcaaatata aaatttaatg aaaatataga actaaatagg aaaacgtaga
      121 cgtaattttc tacgttttcc ttttcatata tattaaatat tacggaaaat tatataaact
      181 aatttagtgt tttgtttgta attcctaatt ttgctccact tttagataat ttttaggtct
      241 atttaactca tcagacattc tatgctcatt tttctccaaa tttgtttcaa ctctttcgta
      301 cttaattttg cgtatttgaa aattcttctt ttagagtact tttattacga tactagtatg
      361 atatatatct atagcaaaca gttaaaatct tcctaaaata agcgaatagc attcctaaaa
      421 cctataaaat ttttagatga agcgacaagt ggacaattaa taaactactt gaacatgaaa
      481 ttatggatca cctttcaaat ttagaaaatg gaattcttat acttattgcg caacatttat
      541 tgattgcaaa attatgtgac aaaaaaaact agtagaagaa agaataatgg cttgataata
      601 aagtac
//
LOCUS       DARBDN010000275          554 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.287, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000275 DARBDN010000000
VERSION     DARBDN010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.287"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>554
                     /locus_tag="SCH06_003005"
     CDS             <1..>554
                     /locus_tag="SCH06_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079486.1"
                     /translation="CFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKK
                     YIFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNS
                     SIPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNA
                     YDIERLLKQKTMKNILKNVKIAES"
BASE COUNT          213 a           68 c          104 g          169 t
ORIGIN      
        1 ttgttttttt cctaatatat atacaggaag agagaataca atacaaattc cattagttac
       61 agctgggtca agaaccgcat tgcaactttc ggatattttt aaccctatga tagatattta
      121 taaagaaaaa aaatatatat tttttacgtc tgtttatgat tttgagggcg gagaacctgt
      181 cggagaatat gaattagtat gcaaaatagc agacttagta ggaaaagata atctaattgt
      241 taagacgcat cctagagatg taagaacaat ttataaagat aatggattta tcgaggataa
      301 aaattcatca ataccttggg aggcgattca attgtcaggc gattttaacg ataaaatatt
      361 tatgacaatt aattcaggaa gtgttatttc aggtagtaca atgtctgcaa aacctgtacg
      421 cacgtattat atgtataaat tgtgtaacat agaaggaaat ccgtcttgca aaaagaatgc
      481 gtatgatatt gagcgattgc ttaagcaaaa aacgatgaaa aacattttaa agaatgtgaa
      541 aatagcagaa agct
//
LOCUS       DARBDN010000276          549 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.288, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000276 DARBDN010000000
VERSION     DARBDN010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.288"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            53..>549
                     /locus_tag="SCH06_003006"
     CDS             53..>549
                     /locus_tag="SCH06_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HEG1079487.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          202 a          100 c           90 g          157 t
ORIGIN      
        1 ttctgtagaa taaagttaac gacaaccaat tcacagaaaa gaggacttcc ctatgaatga
       61 ttttactaca gaaattgtgc aaactctagt cactaaaggc gatttaaatg aattattccg
      121 ttcgcactta gaaaaagcga taaacacact cctacggact gaattaacgg cttttttaga
      181 ttacgaaaaa tatgatcgca ctggttttaa ttcaggtaat tcgagaaacg gttcttactt
      241 tcgatcaatc aaaaccgaat atggtgaatt aacattggaa atacctagag atcgtaatgg
      301 tgagtttaaa caacaaactt taccagccta caaaagaaca aacgatacat tggaaaccac
      361 tattatccat ttattcgaaa aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa
      421 aatgtacggt catcactata ctccacaaac catgtccaac atgactaaag ttctgactga
      481 agaagtaaat gcctttaaat ccagagcctt aaatgataag tatgtcgcta tttttatgga
      541 cgctactta
//
LOCUS       DARBDN010000277          544 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.289, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000277 DARBDN010000000
VERSION     DARBDN010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.289"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..360
                     /locus_tag="SCH06_003007"
     CDS             <1..360
                     /locus_tag="SCH06_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEG1079488.1"
                     /translation="RNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPP
                     RIDTKKLNMLETILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQC
                     ALMERAIAAKRKELDKK"
     gene            366..>544
                     /locus_tag="SCH06_003008"
     CDS             366..>544
                     /locus_tag="SCH06_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079489.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTV"
BASE COUNT          202 a           89 c          116 g          137 t
ORIGIN      
        1 cgaaaccaac cagttgttaa accaaatgca atgcaaatca ataactcatt gaagcgatgc
       61 tttgtgaaag cattggctct acacggactg ggattatatg tatttcaagg ggaagatatt
      121 ccaacaccac ctagaatcga tacaaagaaa ttaaacatgc tagagacgat tctagaagct
      181 ttcaatgagc agatgggtaa agatatgacc aaaaccttaa tcgaatatgt taatgagcag
      241 acagataaat tagggctctt agctgataac gttgaaacta ttgaacagtt aagctatgag
      301 caatgtgcct tgatggagcg agcaatagca gctaagagaa aagaattaga taagaagtga
      361 tatgagtgtt taaaccatta atcgattcat attcagcggt tctgaaaaag ttcaaaggaa
      421 aagacataag cgcaaccatc aatgaggaag tgaacattga tcgactaaag acgatgtatg
      481 acggctacga tggtgatcga gtcattgaaa ttcgttttat tgatcctaga cgtttcaccg
      541 taca
//
LOCUS       DARBDN010000278          528 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.291, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000278 DARBDN010000000
VERSION     DARBDN010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.291"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(107..>528)
                     /locus_tag="SCH06_003009"
     CDS             complement(107..>528)
                     /locus_tag="SCH06_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HEG1079490.1"
                     /translation="DAPNGTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATF
                     TKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYR
                     TYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          166 a          105 c           83 g          174 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaa
//
LOCUS       DARBDN010000279          526 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.292, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000279 DARBDN010000000
VERSION     DARBDN010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.292"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(6..359)
                     /gene="tnpB"
                     /locus_tag="SCH06_003010"
     CDS             complement(6..359)
                     /gene="tnpB"
                     /locus_tag="SCH06_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEG1079491.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(349..>526)
                     /locus_tag="SCH06_003011"
     CDS             complement(349..>526)
                     /locus_tag="SCH06_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079492.1"
                     /translation="IVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNY
                     ILQAILKELLSNAL"
BASE COUNT          153 a          116 c           90 g          167 t
ORIGIN      
        1 ccagcttaaa aaactccttt ttttcctggc aaaatagctc gaggttgatc gatacttaat
       61 ccttctaaca accatcgaac ctgttggttc gttaaggttc gaacttcgtc tttcgtccga
      121 ggccatttta acttgccgtt ttctatccgc ttataacaga gaagaaaacc atcaccgtcc
      181 caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa ataaaaaaac ggcatcttcg
      241 taaagctcga gttgatactc ttgttgaata agactggcaa gaccatcaat tccttttcgc
      301 aaatctgttt ttccgcacac aatataaata tgtttggttt gaagtaaatc ataaagcatt
      361 ggacaacagt tctttcaaaa tagcttgaag aatataattg ttaataccgt tatagatcaa
      421 aacttcagaa ccattctctc ttttgatgcg catcgctaac ttggcagccg cgggtttacc
      481 tttttctggt gcactctttt cgtttcctaa ttggacagga acaatc
//
LOCUS       DARBDN010000280          514 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.293, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000280 DARBDN010000000
VERSION     DARBDN010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.293"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..132)
                     /locus_tag="SCH06_003012"
     CDS             complement(<1..132)
                     /locus_tag="SCH06_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEG1079493.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DARBDN010000281          513 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.294, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000281 DARBDN010000000
VERSION     DARBDN010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.294"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..437
                     /locus_tag="SCH06_003013"
     CDS             <1..437
                     /locus_tag="SCH06_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HEG1079494.1"
                     /translation="KSNGFTPTSIVLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMA
                     DNIPIMLENNYFSYERYSFLMEEELTDSLYEVLKVQGTLAINPGETALEIVTADDQIA
                     KIMEVAVGTPFFFMDTLINDQNNIPIHVGNQYYLGEVYRFYL"
BASE COUNT          169 a           80 c          102 g          162 t
ORIGIN      
        1 gtaaatctaa tggttttaca ccgactagca ttgttttgga acgcaagatc attccagcaa
       61 ctgaagggat ggcaaaaaaa ctcgatatcg ctcaaggtga tgatgtttta tatatccaga
      121 gaaagcgaat ggcggataac atccccatta tgttagaaaa caattatttt tcttatgaaa
      181 gatatagttt cttaatggag gaagagctga ctgattcttt gtatgaagta cttaaagtcc
      241 aaggtacctt agccatcaat cctggggaaa ctgcacttga aattgtcaca gctgatgacc
      301 aaattgccaa aataatggaa gtagctgttg ggacgccctt tttctttatg gatactttaa
      361 tcaacgatca aaacaacata ccaattcatg taggtaatca atattacctg ggagaagtat
      421 atcgttttta cttatgattt cctgtttgga tttcaaggag tagattttat ttatgaagca
      481 aatattgcgg tcaaaaatga tttttgatgg aga
//
LOCUS       DARBDN010000282          503 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.295, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000282 DARBDN010000000
VERSION     DARBDN010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.295"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            10..375
                     /locus_tag="SCH06_003014"
     CDS             10..375
                     /locus_tag="SCH06_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1079495.1"
                     /translation="MVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPDGKT
                     MFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEKLGG
                     KNDYKDEIVYVYDYEKGDK"
BASE COUNT          201 a           35 c           86 g          181 t
ORIGIN      
        1 gatgataata tggtttttga tattgataat ttaaaaggat ttcttaatga taccagttca
       61 tttgggttta tagctaaaga aaataataaa attataggat ttgcatattg ctatacactt
      121 ttaagacctg atggaaaaac aatgttttat ttacactcaa taggaatgtt acctaactat
      181 caagacaaag gttatggttc aaaattatta tcttttatta aggaatattc taaagagatt
      241 ggttgttctg aaatgttttt aataactgat aaaggtaatc ctagagcttg ccatgtatat
      301 gaaaaattag gtggtaaaaa tgattataaa gatgaaatag tatatgtata tgattatgaa
      361 aaaggtgata aataaatgaa tatagttgaa aatgaaatat gtataagaac tttaatagat
      421 gatgattttc ctttgatgtt aaaatggtta actgatgaaa gagtattaga attttatgat
      481 ggtagagata aaaaatatac att
//
LOCUS       DARBDN010000283          502 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.296, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000283 DARBDN010000000
VERSION     DARBDN010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.296"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            338..>502
                     /locus_tag="SCH06_003015"
     CDS             338..>502
                     /locus_tag="SCH06_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEG1079496.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIAC"
BASE COUNT          177 a           89 c           74 g          162 t
ORIGIN      
        1 tctgtactga aatcaaggta ttattgggaa tcccagctta aatcatagat accgtaaggg
       61 attttattct ttatttaaaa ctttgcaaca gaaccttttg ccatatctac tccccctcta
      121 atttatatct ccattctaac gtacttaatt aagtacgtaa attcgattgt tttgtttaaa
      181 ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc ctttataccc gtggtgctag
      241 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
      301 gagtagtctc aaaactccca agaaatgagg actacatatg cgttcatcaa aatatactga
      361 acattataca gatactttta taacattcaa ggaaattatg agaactgttt ctaacatata
      421 ccacaattgt gtaccagata agattaaaaa ccgaagaaat actgatcaac tgaagcaacg
      481 cgatacagtg attattgctt gt
//
LOCUS       DARBDN010000284          463 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.297, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000284 DARBDN010000000
VERSION     DARBDN010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.297"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..147
                     /locus_tag="SCH06_003016"
     CDS             <1..147
                     /locus_tag="SCH06_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEG1079497.1"
                     /translation="RKRRMTFKELAALIGISGAYLSDILNGNRDGKKAQQHIETVKKI
                     LDIR"
     gene            159..407
                     /locus_tag="SCH06_003017"
     CDS             159..407
                     /locus_tag="SCH06_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079498.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKVTPKEFIEKHLVDL"
BASE COUNT          185 a           69 c           91 g          118 t
ORIGIN      
        1 agaaaaagaa gaatgacttt caaagaacta gctgcgctta tcggtatttc aggagcttat
       61 ttatcagata ttctaaacgg caatcgtgat ggaaagaaag cacaacagca tatcgaaaca
      121 gtgaaaaaaa tattggacat ccgatagggg ggtaggcgat gacaaaacta aaaaaacaag
      181 attttgtaaa aaaatacaat tattctccat ctacttatca acgtcgaatg tcggaactaa
      241 aaaatacagc aattttctca gcggcgtatg aacgggtcac aggacaagaa gtttggatca
      301 atacagaatt atacgataaa tttttgtctt tcaaatccta taacaggtta cgcacaagaa
      361 aggtaacacc taaagaattt atcgagaagc atttagttga tttataaaaa acagaacatt
      421 ttgagaggtg aaggttaatg ggtaaattca acagagcatt ggt
//
LOCUS       DARBDN010000285          453 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.298, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000285 DARBDN010000000
VERSION     DARBDN010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.298"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            28..>453
                     /locus_tag="SCH06_003018"
     CDS             28..>453
                     /locus_tag="SCH06_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HEG1079499.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAF"
BASE COUNT          156 a           71 c           95 g          131 t
ORIGIN      
        1 tagaaaaaga tagcaggagg aatgacgatg aatcatttta aaggaaagca atttcagcag
       61 gatgtgatta ttgtagccgt gggctactat cttcgttata accttagcta tcgtgaagtt
      121 caagaaatct tatatgatcg tggcattaac gtttctcata cgacgattta tcgttgggtg
      181 caagaatatg gcaaactact ctatcaaatt tggaaaaaga aaaataaaaa atccttttat
      241 tcatggaaaa tggatgaaac gtacatcaaa attaaaggaa aatggcatta tttgtatcga
      301 gccatcgatg cagatggttt aaccttggat atttggttac gtaaaaaacg ggacacacaa
      361 gcagcctatg cttttcttaa gcggttagtg aagcagtttg atgaaccgaa ggttgtagtc
      421 acagataaag ccccctctat tacaagtgcc ttt
//
LOCUS       DARBDN010000286          452 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.299, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000286 DARBDN010000000
VERSION     DARBDN010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.299"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>452
                     /locus_tag="SCH06_003019"
     CDS             <1..>452
                     /locus_tag="SCH06_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079500.1"
                     /translation="GKPNLMSKLKSSDFNVGYHGSLTSDNEKLHFTSDGTGSIIMFTR
                     INTPQLASGKTYTLSAKVRFDEGTTGAIDKLRLVYRTSPGEKILLEANSTNITTDDVG
                     KEITIKGTANVNYQITNLDRFYMSISFVDRDKINGGFKLYDIKIEEGST"
BASE COUNT          165 a           68 c           92 g          127 t
ORIGIN      
        1 ggtaagccga atttaatgtc caaactaaaa tcgagcgatt ttaacgttgg ttaccacggg
       61 tcactaactt cggataacga aaagctacat tttacttctg atggtacagg aagcattatt
      121 atgtttacgc gtattaatac acctcagctt gctagtggga aaacctatac tctgagtgcg
      181 aaagttcgat ttgatgaagg aactacagga gctattgata aattacgttt ggtgtatcgt
      241 acatcaccag gagaaaagat attattggaa gcaaatagta caaatattac aacagatgat
      301 gtagggaaag aaataacaat caaaggtaca gctaacgtta attatcaaat cacaaattta
      361 gatcgatttt atatgagtat tagctttgtt gacagggata aaataaatgg cggatttaag
      421 ttgtacgaca tcaaaatcga agaaggctca ac
//
LOCUS       DARBDN010000287          449 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.300, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000287 DARBDN010000000
VERSION     DARBDN010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.300"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          152 a           73 c           95 g          129 t
ORIGIN      
        1 tcattgcaat aattgcaaca aagaaatttc atcgggggaa gaggtttgga caaaaatgga
       61 aatttccgcc aaaagtaact gctcctcaac tgaaatcaat taaagaacta gaatttgaga
      121 atgcactggt aatttgtatg acatgtactg atgaagtatt tcgaaaacat ttttaaaggt
      181 tgagatgtat atagatttaa ccaatcattt atctctctcg gaaaaggaat attaactaac
      241 cagcgggtta tcaaaaatag gtaggaaaac tgtacttaat ggcttatttc gcgctgatta
      301 tgagaatatc agtctgtttg attaattttt agggttcaaa atacagagac aaactccagg
      361 tcgggtttcg ccacaagcga attacccgat ctggagtttt gtctattgca ggaaggcgta
      421 gccggactgc aggaataaag cccccggtt
//
LOCUS       DARBDN010000288          442 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.301, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000288 DARBDN010000000
VERSION     DARBDN010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.301"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..442
                     /locus_tag="SCH06_003020"
                     /pseudo
     CDS             1..442
                     /locus_tag="SCH06_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
BASE COUNT          163 a           81 c           78 g          120 t
ORIGIN      
        1 gaactagtcg gaattataga tagttttcct agtccattat gtaaaccagt tagaaataga
       61 caagcaaaac tattgaatca aatagccaaa gttggctata actcaacaaa aaaatcttat
      121 ttttatggtc ttaaaattca tatgatcgtt actaagactg gctttccgat tacttactca
      181 atcgcgaatc caggtgtccc tgacgtgaaa gtgttagaga ctttatcgga agaagcgaat
      241 cttcccaata tcctagggga caaaggatat attagccata aaatccatga aaagcttgcc
      301 cttaagggca ttactatatc cgttccgcca cgtaaaaaca tggataaatc agaaaaacta
      361 gaccacagct tacttggaaa acaaagaaaa attaggttgt caaaatttca actcacgttc
      421 tgttaaaggg ctagagagta ga
//
LOCUS       DARBDN010000289          440 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.302, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000289 DARBDN010000000
VERSION     DARBDN010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.302"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            17..220
                     /locus_tag="SCH06_003021"
     CDS             17..220
                     /locus_tag="SCH06_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HEG1079501.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            220..>440
                     /locus_tag="SCH06_003022"
     CDS             220..>440
                     /locus_tag="SCH06_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEG1079502.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFI"
BASE COUNT          167 a           48 c           85 g          140 t
ORIGIN      
        1 aaagaaaaag aaagtattga aacattgtgt tattctagga atattaggaa cttgtctagc
       61 tggcattggt acaggaatag acgttgacgc agctacttac tatggaaatg gtctttattg
      121 taacaaagaa aaatgttggg taaattgggg acaatcatgg tcagaagggt taaaacgttg
      181 gggagataat ctttttggta gttttagtgg aggacgataa tgacttcaat aaacattgat
      241 cacacaaaaa aagtcataca tgaattatac aatagtttaa tgacacgacc taatcagacg
      301 aaagcattat tagatattac tgatgtttta tttcaggtat ataaaaaaat tgatacagca
      361 aaatatcctg aaattcttgt aaataaatta gttaattata tttacatcgt gggttttgat
      421 aataaaatac gctttattga
//
LOCUS       DARBDN010000290          429 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.303, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000290 DARBDN010000000
VERSION     DARBDN010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.303"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>429
                     /locus_tag="SCH06_003023"
     CDS             <1..>429
                     /locus_tag="SCH06_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079503.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGFILST"
BASE COUNT          157 a           75 c           88 g          109 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgagaaa aacaatttgc ttattctgcc catacttcat gcgacgacaa tggatttatt
      421 cttagcaca
//
LOCUS       DARBDN010000291          423 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.304, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000291 DARBDN010000000
VERSION     DARBDN010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.304"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>423
                     /locus_tag="SCH06_003024"
     CDS             <1..>423
                     /locus_tag="SCH06_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079504.1"
                     /translation="YYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALSGAILVYY
                     VLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGARLSFYLYS
                     SKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIA"
BASE COUNT          135 a           42 c           79 g          167 t
ORIGIN      
        1 tttattacgt attttttgaa aataaaaata caaaaaaaca taagataaaa attatcgtat
       61 ctttaatttt aattttcatg ggattgaaga gaattgaact gttagcttta agtggtgcaa
      121 ttctagtgta ttatgtttta ttaaagtggg gaaaaaagat tcaaatccgt gcattagtgt
      181 gtactatttg tgcaactgtt atttcgttag tgtttattta cattatagat acaggaattt
      241 tggcattgct tatgtcaaat ttgggcatta cagatgacgg tgcgaggctt tcattttatc
      301 tatattcatc taaattttat gaacttggtt taggatatgt aggaacagga tggacatggt
      361 tttcaaaata cttttttaat ctttatttat cgcactttag gttaaatggt ggaagaattg
      421 cag
//
LOCUS       DARBDN010000292          415 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.305, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000292 DARBDN010000000
VERSION     DARBDN010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.305"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..339)
                     /locus_tag="SCH06_003025"
     CDS             complement(<1..339)
                     /locus_tag="SCH06_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079505.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DARBDN010000293          365 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.307, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000293 DARBDN010000000
VERSION     DARBDN010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.307"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>365
                     /locus_tag="SCH06_003026"
     CDS             <1..>365
                     /locus_tag="SCH06_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079506.1"
                     /translation="NTKEIAKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISC
                     GKSNRYAYYLKNCKSEYFDEFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYG
                     VDIIPTARTKAIAVLNYLK"
BASE COUNT          142 a           36 c           67 g          120 t
ORIGIN      
        1 aaaacactaa agaaattgcg aaaaaaatag aagaaaaaaa agtgtttgat ggctgtcatt
       61 atttagaaag caaatctttt gatgataata ttgggtattt tcaaaagatt aaggactgtc
      121 ttcagatttc ttgtggtaaa tcaaatcgat atgcctatta tttgaaaaac tgtaaaagtg
      181 aatattttga tgaatttatt tgtttttcaa tgggagaggt ttggttggaa ggaatatatg
      241 cttgcttata tcgaaataat aaaaatgtac aggtatcaat tttagaagaa ggtattttaa
      301 gctatggagt tgacattatt ccaacagcaa gaacaaaagc tatcgcagta ctcaattact
      361 taaaa
//
LOCUS       DARBDN010000294          342 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.308, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000294 DARBDN010000000
VERSION     DARBDN010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.308"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          125 a           30 c           59 g          128 t
ORIGIN      
        1 atgtatagtt tttattatat ggatgttttg gttatttttt gtgaaaccga taagactaac
       61 taaaaaattt ggattgaaaa caggggagtg tgtattatta ttaactatat atatgtttat
      121 attatatttg acggataata cgctcactta tccagacact caaatgattt ttctcttagt
      181 acctatgata gtttcgtggg ttgataatca acaacgaata tcggaataga tagctaaagt
      241 atattttaat tatgaattta taattagttg taaaagttaa tatttaacgg acaggaagta
      301 gggtgaaaaa atttgaaaaa aattttagtg ttagcaaata ca
//
LOCUS       DARBDN010000295          341 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.309, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000295 DARBDN010000000
VERSION     DARBDN010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.309"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>341
                     /locus_tag="SCH06_003027"
     CDS             <1..>341
                     /locus_tag="SCH06_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079507.1"
                     /translation="EATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEP
                     DAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNR
                     SDADKYEPTVEG"
BASE COUNT          141 a           50 c           76 g           74 t
ORIGIN      
        1 gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc aacaaaactg
       61 gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac tacagaattg
      121 aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc aaaagatact
      181 aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa agggactgtt
      241 gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac agtgacagac
      301 aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DARBDN010000296          339 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.310, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000296 DARBDN010000000
VERSION     DARBDN010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.310"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
BASE COUNT          137 a           34 c           58 g          110 t
ORIGIN      
        1 aaaataggga attttctatt gcaattttat aaagagattg ctatattatt atttgttcta
       61 aatgattcct ttaaggtgtc actaaaaatt ataaaaaata gtgttgacgc acttttgatg
      121 tcatgttata ataacgaagt cgtttggatg agatagctaa taaagcttga ttttatcgaa
      181 aaaaacttcg aaaaagttat tgacaaataa caataaagat ggtatgataa tcaagtcgct
      241 gctaatgagt ggcaaagacg tttagaaaaa ataaacaaag aagttgttga cattctcttc
      301 tgaatctgat aagattaaag agttgttaaa acaaaaaga
//
LOCUS       DARBDN010000297          329 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.312, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000297 DARBDN010000000
VERSION     DARBDN010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.312"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>329
                     /locus_tag="SCH06_003028"
     CDS             <1..>329
                     /locus_tag="SCH06_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEG1079508.1"
                     /translation="YVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIVFT
                     MLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIWGI
                     ISKGWYM"
BASE COUNT           91 a           54 c           72 g          112 t
ORIGIN      
        1 gatatgttgg gtcgacgatt aatcccttca acgttttaat cgcacaggga gtagctggcg
       61 tttacggaaa tcccctgctt tggtttcgga tgctatcctg gattgtcatt actgggattt
      121 caattgtttt caccatgctt tatgctagca gagtcaaaaa gaatccactg tcctctattg
      181 tttatgagag tgatttaaag gttaagcata agtttcaaaa ttttgacact gaaaaagagt
      241 tttcaacaca agataaacta attatcgccg gttttatcgt aggtttagga atcatgattt
      301 ggggtatcat ttccaaggga tggtatatg
//
LOCUS       DARBDN010000298          321 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.313, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000298 DARBDN010000000
VERSION     DARBDN010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.313"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>321
                     /locus_tag="SCH06_003029"
     CDS             <1..>321
                     /locus_tag="SCH06_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEG1079509.1"
                     /translation="AIISLIYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGE
                     LKQQINDLYSTLLRTIDDLEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENM
                     KYNIG"
BASE COUNT          146 a           31 c           40 g          104 t
ORIGIN      
        1 gctattattt ctttaattta tgcaaaatca ataaaaaata atatacaaga aataaaaatt
       61 gttactgata aaatgatgaa acttgataaa aaaatgagtt taaaagttag ctctaatgat
      121 gaagttggag aattaaaaca acaaattaat gatttgtatt ctactttatt aagaacaatt
      181 gacgatttgg aatttaaaaa taaagaaatt ttaaaattag aaaagttaaa atatgacttt
      241 tttaaaggtg catcccatga acttaaaacc cctcttgcta gtcttaaaat aatactggaa
      301 aacatgaaat acaatattgg a
//
LOCUS       DARBDN010000299          321 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.314, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000299 DARBDN010000000
VERSION     DARBDN010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.314"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(69..321)
                     /locus_tag="SCH06_003030"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="SCH06_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DARBDN010000300          317 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.315, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000300 DARBDN010000000
VERSION     DARBDN010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.315"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="SCH06_003031"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="SCH06_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HEG1079510.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          100 a           48 c           50 g          119 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcat
//
LOCUS       DARBDN010000301          315 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.316, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000301 DARBDN010000000
VERSION     DARBDN010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.316"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>315
                     /locus_tag="SCH06_003032"
     CDS             <1..>315
                     /locus_tag="SCH06_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HEG1079511.1"
                     /translation="PIEFDNDERLLLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRS
                     YLSDRVFDVLEKLSKSGILKEEYDSSFDEYPSRYILISEDYKKFKRYFLKNEKKISVI
                     MEK"
BASE COUNT          124 a           28 c           57 g          106 t
ORIGIN      
        1 ccaatagaat ttgacaatga tgaaagattg ctgctaatat atgcgtttat ggatgaaaat
       61 tctatctttt caactgataa ttcaacttat agaaaagtag ttcaatggga aagtgataac
      121 aatttaagga gttacttgag tgatagagta tttgatgtac tagaaaaatt aagtaaatcg
      181 ggaattttaa aggaagaata cgattcttct tttgatgagt atccatcacg ctatattttg
      241 atttcagagg actataagaa atttaaaagg tattttttaa aaaatgaaaa aaagatatct
      301 gttattatgg agaaa
//
LOCUS       DARBDN010000302          308 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.317, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000302 DARBDN010000000
VERSION     DARBDN010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.317"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(76..>308)
                     /locus_tag="SCH06_003033"
     CDS             complement(76..>308)
                     /locus_tag="SCH06_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079512.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           94 a           46 c           56 g          112 t
ORIGIN      
        1 atgttggtga agttcaccaa catcaaaaag tatagagccg atagaaggac tgaccttctg
       61 tctcagattt ttttgttatt tcacttgaat caattgattg atcaaaaaaa tcctgatttt
      121 catgttctca aatgatttaa atccataaga taatcgtttc agtgtcttga tatggggaat
      181 cttggcctct attttgccat tagaatacgg gtaaatcata gcattgtaaa taccttcttc
      241 atacgttaaa aggttttgaa gtttcgtgcg aagttgtgca tcaagtgttt caggaagatt
      301 ttttaata
//
LOCUS       DARBDN010000303          300 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.318, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000303 DARBDN010000000
VERSION     DARBDN010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.318"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>300
                     /locus_tag="SCH06_003034"
     CDS             <1..>300
                     /locus_tag="SCH06_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079513.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSI"
BASE COUNT          117 a           57 c           48 g           78 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
//
LOCUS       DARBDN010000304          299 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.denovo.319, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000304 DARBDN010000000
VERSION     DARBDN010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.denovo.319"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..>299
                     /locus_tag="SCH06_003035"
     CDS             <1..>299
                     /locus_tag="SCH06_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEG1079514.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DARBDN010000305        12691 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.076, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000305 DARBDN010000000
VERSION     DARBDN010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.076"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(55..198)
                     /locus_tag="SCH06_003036"
                     /pseudo
     CDS             complement(55..198)
                     /locus_tag="SCH06_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(433..1095)
                     /locus_tag="SCH06_003037"
     CDS             complement(433..1095)
                     /locus_tag="SCH06_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEG1079515.1"
                     /translation="MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGC
                     GSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIV
                     SRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCF
                     KFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVW
                     TK"
     gene            1487..1546
                     /locus_tag="SCH06_003038"
     CDS             1487..1546
                     /locus_tag="SCH06_003038"
                     /inference="COORDINATES: protein motif:HMM:NF033690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythromycin resistance leader peptide"
                     /protein_id="HEG1079516.1"
                     /translation="MGTFSIFVINKVRYQPNQN"
     gene            1604..2335
                     /gene="erm(A)"
                     /locus_tag="SCH06_003039"
     CDS             1604..2335
                     /gene="erm(A)"
                     /locus_tag="SCH06_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(A)"
                     /protein_id="HEG1079517.1"
                     /translation="MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHF
                     TKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNI
                     PYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
                     LYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKH
                     ANVTNINKLSKEQFLSIFNSYKLFH"
     gene            complement(2461..3243)
                     /locus_tag="SCH06_003040"
     CDS             complement(2461..3243)
                     /locus_tag="SCH06_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(9)-Ia"
                     /protein_id="HEG1079518.1"
                     /translation="MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRI
                     NSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYP
                     PKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLT
                     DIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEH
                     VTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN"
     gene            complement(3397..3774)
                     /locus_tag="SCH06_003041"
     CDS             complement(3397..3774)
                     /locus_tag="SCH06_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEG1079519.1"
                     /translation="MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNS
                     IAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVME
                     LEKENKKLQNQIQKLYGDLYNKE"
     gene            complement(3781..5673)
                     /locus_tag="SCH06_003042"
     CDS             complement(3781..5673)
                     /locus_tag="SCH06_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1079520.1"
                     /translation="MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPS
                     AIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKM
                     LDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSY
                     YVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYF
                     KQLVKRYCKLRLNMDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSE
                     LNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEF
                     VLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKM
                     KKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQ
                     NIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETL
                     KNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGC
                     PHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQI
                     IGSLTG"
     gene            complement(5670..6755)
                     /locus_tag="SCH06_003043"
     CDS             complement(5670..6755)
                     /locus_tag="SCH06_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEG1079521.1"
                     /translation="MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPN
                     TIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREE
                     TTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRV
                     KKKQIRTLRSEEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIH
                     LTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFG
                     KPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTT
                     LNTYVHLSDQDMKNEFNKYLERKEHKK"
     gene            complement(6886..7437)
                     /gene="radC"
                     /locus_tag="SCH06_003044"
                     /pseudo
     CDS             complement(6886..7437)
                     /gene="radC"
                     /locus_tag="SCH06_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
     gene            complement(7492..8145)
                     /locus_tag="SCH06_003045"
     CDS             complement(7492..8145)
                     /locus_tag="SCH06_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEG1079522.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            complement(8135..9448)
                     /locus_tag="SCH06_003046"
     CDS             complement(8135..9448)
                     /locus_tag="SCH06_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEG1079523.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            complement(9758..12403)
                     /locus_tag="SCH06_003047"
     CDS             complement(9758..12403)
                     /locus_tag="SCH06_003047"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEG1079524.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     misc_binding    complement(12451..12667)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         3778 a         2624 c         1908 g         4381 t
ORIGIN      
        1 acaaaattac aatataattg tacacttgct tcattttttt tgcaagaaag caacttactt
       61 ctcttccatc attccttctt ctctcaaact aaaatatcgt ttgcgtccga tgatcaagtg
      121 gtccagtaca gtgatcccca tcatttctcc acacttttgt atccttttgg taaaattcat
      181 atcctgctgc gatggaattt catattatca agagtaaatt acaaaagaat catttaaatc
      241 aatactttca ctttgaatac atgtatttga agtggaaggt acttatttca aaaatagtaa
      301 aacctgtatc ttaaattact taatagtaac ataagataca ggctgatttt ttattcattg
      361 ttatttatac taaagcaccc gatagctctg aaaacaatca caaattcaac ttttcaaagc
      421 cacagcttta agttattttg tccagacaac ccccattgcc caacccattt tatggaattg
      481 gcatccaggc aacaactttt catataaatc gtaataattt tgttcagata ggtacttatc
      541 tgaagctaaa tgctcaagcc atgatttaga tgtgttgtga ttataaattc taatcgcatt
      601 ttttattcca aatttgaaac aatgcggtaa aaactcttgg attgccccta atttataaac
      661 ataggtaggc ggtgtctcga cttcagatac attatcaaga ataactattc ttccttcctc
      721 attcaacagt tccttcattt gctgtattac gctggctata tcatccaaat gatgaaaggt
      781 tgttcggctt acaataaaat caaacttctc attaaaatta agttgttctg cattcatatt
      841 cagatagacc gtatttgtta gttgacgttt agatttggca agatcgagca tttgattaga
      901 aatatcaatc cctaccactt catcataata acttgctaat ttctccacta acaaacccga
      961 gccacatccg atatctaatg ctctgccttt ctttggagac atattagaca caaagaatga
     1021 ataatcattc aaaagctcat tcacgaaatc gtaatcttct gcaaccttat caaactgtga
     1081 ttctattgta ttcaaaaaga tcccccattc ctactttatc gacattcttt cattacttac
     1141 cactttagat gttttttcgt tggggataaa acttcccttt agacaatttt atccaaagac
     1201 aatacaacag tgcaacttta ttaaagtcac tgtcctttat cgcagccttt actttttagt
     1261 aaagacagtg gcttctctta tcaagtttca aaacatatta ttttgaagaa aacgtccatc
     1321 tgaagtgtca agtgcaaaat tacatataaa ggtttattct aaaatgaaaa gatgatacaa
     1381 tcatattcag ttacataagg aggtttcaat tatgtgcacc agtatcgcag tagtagaaat
     1441 tactttatct cattcataat gaaaaaaatg gaaaggagat aaaagtatgg gtactttttc
     1501 tatatttgtt attaataaag ttcgttatca accaaatcaa aattaattgg ttataatgaa
     1561 cgcttaatgt cagttcatta taaccagtaa ggagaaggtt ataatgaacc agaaaaaccc
     1621 taaagacacg caaaatttta ttacttctaa aaagcatgta aaagaaatat tgaatcacac
     1681 gaatatcagt aaacaagaca acgtaataga aatcggatca ggaaaaggac attttaccaa
     1741 agagctagtc aaaatgagtc gatcagttac tgctatagaa attgatggag gcttatgtca
     1801 agtgactaaa gaagcggtaa acccctctga gaatataaaa gtgattcaaa cggatattct
     1861 aaaattttcc ttcccaaaac atataaacta taagatatat ggtaatattc cttataacat
     1921 cagtacggat attgtcaaaa gaattacctt tgaaagtcag gctaaatata gctatcttat
     1981 cgttgagaag ggatttgcga aaagattgca aaatctgcaa cgagctttgg gtttactatt
     2041 aatggtggag atggatataa aaatgctcaa aaaagtacca ccactatatt ttcatcctaa
     2101 gccaagtgta gactctgtat tgattgttct tgaacgacat caaccattga tttcaaagaa
     2161 ggactacaaa aagtatcgat cttttgttta taagtgggta aaccgtgaat atcgtgttct
     2221 tttcactaaa aaccaattcc gacaggcttt gaagcatgca aatgtcacta atattaataa
     2281 actatcgaag gaacaatttc tttctatttt caatagttac aaattgtttc actaaattaa
     2341 agtaataaag cgttctctaa tttcacaaga ggacgcttta ttcttcccaa aaattgttca
     2401 atatttatca ataaatcagt agttttaaaa gtaagcacct gttattgcaa taaaattagc
     2461 ctaattgaga gaagtttcta tagaattttt catatactta acgagtgctt tcacctttga
     2521 atatagtcct tcccacttat catcacactc tccccgatag ccttttctag ctatatccag
     2581 taaagttaca tgctctttag gtaaaagagg tatagcccat tctgcagcga catctttcga
     2641 ggtaatttca ccagtagtca ctgtttgcca cattcgagct agggttaaaa ttacattacg
     2701 ctcatcacct tttatcccct caattagttc tggcaaagaa tccttaattg ctcttcgaat
     2761 atctgtcaaa ggtacggaga caagtatact tgaagaatca ggaccaaata gagaaatact
     2821 attctttctt gcttgtgcta aaacaatagc caaatcagga tcatagcttg gttcctgaat
     2881 ttgtccattc tcaaattcac ccctgagcca ctcaccgtat ataaattctc tttttggagg
     2941 atattgccaa gggacaactt cactcctatt tataaccgta acttcaagtg gtctaacaga
     3001 atccgtattt ccaatctttc ctgatatagt cattagtctt tctgttagtt tttttcgagt
     3061 taattgaggt aaactatgat tcacgacgac tagaacatct acatcgctgt taatgcgtaa
     3121 accaccattt actgctgaac caaatagata tactccaact attgaacttc caaataaatc
     3181 ttttacgatt tttaatgttt gaatcgcttg atttggtatt tttccgttaa tcaaattgct
     3241 catgatttca cctcgtaact gattatgttc atataaagtt tatattgata ctcaatttac
     3301 ttaccctaga ttggacatat acctaaatga ctgttcaata aagctgaccg ttagcgttta
     3361 agtacatcct ttcacaattt gtctacagat taataattat tctttattat acagatctcc
     3421 atataatttt tgaatttggt tctgtaattt tttattttct ttttctaatt ccattactct
     3481 tctttttaag gttttaataa ggatttcctc cgaacgagaa cttttcttgg gttttgagac
     3541 tacatttgct gttatttgac gctcacgaag ggattcgatt ctttgcctaa tatcgtgttc
     3601 cttataaagc catgatttag aaacattagc ttcctttgct attgaattaa aattaataac
     3661 tttaccttca atcgaaaatt tagaaatcgc tttgtctact ttttcccttg tcttttttga
     3721 tttctgcttc gccaaacgta caatttctgt tgtatttcta acttgtttat ccattgataa
     3781 ttaccccgtc aaacttccaa tgatttgttc taaacgctct ttaacacggc tattagtctc
     3841 tacttgtctt tgccattgtt tatccttagc tatggctaat aactcttctg tacgctctaa
     3901 ctgttcttcg tgctgtggta agaattgctt actggtacag aagtgagtgc aatctaagca
     3961 tgcattcgca tgtggacaac cacctgctac tactggcaat ctacaataac catttggaag
     4021 cacttgtgca tttatatttt tcttgaacca ttgaagctct acatcatcga cttcattatc
     4081 ttcatctaga tcaagcacat ctccattatt ggtaaccagt ttttcctgaa atttagtaaa
     4141 ttcatttttt agagtttcat caaagatatg agcgtatctg cttgtcattt ctgggctttc
     4201 atgccccaaa aatttctgca caatatgctg gggcatcccg ttgttaatca ttcttgttcc
     4261 tactgtatgg cgaaaggcat gggcatggaa tctataaatc tcacctgatt tatccactat
     4321 attttgctca taagctaatt tatttaactc acctctaaat gtttcttgtt ttaatggcga
     4381 tccatctttt cttggaaaga ggtattcact atctggaaat tcctctgaaa ctttatcttc
     4441 ccgaacttta ataagtaaag ctacctcttt agatattgga actatatgct cctttttcat
     4501 tttccattga taatacttta aaaagaaatc tccatctttg tcctctaata gacagccttt
     4561 tttcaaggtg cacaattcac ttatcctcat tccacattct tgaacaatca tagtcatcgt
     4621 agctatatat tcgggtaatt tatcaagatg actgttcaat tgctctagga cgaattcatc
     4681 tataaagcgt ggttttgctc ttggtatttt cggatagtcc tcagaataaa ttaatatttt
     4741 ggaaggaaca tcatcccatt ctagcctaag aagggtacta aatagtcctt ccaatataga
     4801 gatcctccca gttattgtac taggttttat tcccatcatg tttagttcac ttaaatatgc
     4861 ttcaatttcc actctcgtta attggtgtac tctctgaact tgtttaaatt tcatgtccag
     4921 aaaattaaag aactctttaa gtctttgggc aatatcactt acataggaaa agctatccat
     4981 gttcaatctc aacttacaat atctttttac aagttgttta aaatatgtat tccgaaaccc
     5041 tttaaagtta attgtatatt catattgtgt tgggttaacc ttatcatctg gcaaaggtaa
     5101 gttacgtcta tcccaaacgt ctttatccca ctcctctcca tcaaaataaa agttctcata
     5161 aaactccata aattgtttta gattagtaac atagtaggaa ttagctttta caggtgtttt
     5221 ttcttgatta gcagtaatct tataattagt agtggtaatt ctaacacccc gttttgtcaa
     5281 ataagttcta tactccgtca ttgctttttc aataggaact tcagtaattg aagtaatgct
     5341 aggatacttt aaatctaaga aatctaacat tttattaatt actgttcctt ttctaatcca
     5401 gacagttttt gcattccata ttccattgtt taaatggtaa aaataaaaat atttcaattc
     5461 tgttcttaac cacagatttt taacacgttc aaaacgaacc caacgattcc ttaaagcagg
     5521 attcttactt aattctatgg cagaaggatg tggacatttt cttatatccc aactattatt
     5581 agcccaaaac ccctgcattt cttcattcat tacagctatt tttttgctaa tctcactctg
     5641 actaataatt ttccttttac tagaagcatt catttcttat gctcctttct ctcgaggtat
     5701 ttattaaact catttttcat atcctgatct gaaagatgaa cataggtatt taacgttgtc
     5761 tgaacatgtg cgtgacctaa tctcttttga acgaacgcaa catcccatcc ttccctaatt
     5821 agctgcgttg cgtgagtgtg gcgaagcata tgtgatgtaa attctattcc agtcctttta
     5881 actattcttc taactagatc aagaacactt tggtacttta gtggtttccc aaaatagcct
     5941 tcttttaagg aaataaaaac ataatcatgc tccaattcct cactatactc atatatcaag
     6001 taatctgtat aaagtgacat aagttcttta ctcacatgta ttgttctttc cttccttaat
     6061 ttaatataag cttcattaac attaacatct ctaggtgtta aatggatttg attgtcccaa
     6121 gtgacaatat cttcaagcct aagcgataac acttcaccga ttcttaaacc accctcatac
     6181 ataagcatta aaattaattt atctcttttc gtatgacaag catcaataat ttgcttaact
     6241 tcctctgatc tcaatgttct tatctgtttc tttttaaccc ttaactttaa gacattcttt
     6301 tggtatctac ccttattaac atgatgtaaa aatcctttga aatttcttcc ctttgcttgt
     6361 ttaaatacat caattgattt aaattctcct aatctactta aataatcaag aaaactcata
     6421 actacattta aaattgtatt cactgtcgtt tcttctctta tggctttttt tgactgaaga
     6481 tcaattacat ttgatgctga aggatatctc aaccaaccta cgaagtctgc taacaactca
     6541 aagttaatat cattaagaat aacacctctc tgttccatga actcgtacag caactttaaa
     6601 tgatagcagt atgctttaat ggtattagga gacttaccag tattatctaa gtatttaata
     6661 aatttcatta ctggttctat tagctggtat tctttatcta gtaataaata caatggatac
     6721 ggcttattct ccacttctat cctttgaacc ttcacatgtt cccacctctt taaatacttt
     6781 aactactaca aattataaac cttgttaatt tttatttaaa gtaaaatatc cctttaatat
     6841 ctcctcttaa actactttaa ctactattat ttattatact atggttaaaa cattaccaga
     6901 aggatgatta tgcgctaaaa cgatccttgc tgcacaataa cgtacagcat aatggaaaat
     6961 ttctctagga tgagcgactg actgattcag cgaaccgatg aacactgttt tttttaagat
     7021 cacttgattc ttcgtgtcca aataaataca aaccaaatgt tcttgtttgt gatctttcat
     7081 ttccagaatc aattgctggg ccaattcgta gctggtacga accggtggag ccgctctttc
     7141 atgatccgtc tgaattcgtc gacctaattc gatcaaggct ttgatttcga ttgctttcac
     7201 gcgtcctatc cctcgaatct cttctaactc atgcaaagta gcctgtcgta aagaggccag
     7261 tcctccaaac gtttttaaca gatttccagc aatcgacatc acactataag ggtgttgacc
     7321 ggtacgcagt aagattgcca aaagctcctg atccgataaa gcttccgcgc cataaatttc
     7381 catacgttcc cttggtaaag agctagtagg tacttctttg atcaatcgtt ttcccaaaaa
     7441 aacatctcct ttctatctta tctaaaataa gatacgaaaa gagatggatt tttattttaa
     7501 caatgcaggg atttcatgta aagaagaaac aaccccagct gtttttttga tcaattcttg
     7561 ggatggtgga agcagatctg gtaccatgac taccgggatc tcagccgcag aagctgctaa
     7621 aataccattt tgtgaatctt ctaaaatcaa tgtttctttc ttcgctgtac ctagcttctg
     7681 attagctaac aagaaaattt ctgggtctgg ttttgctcgt tgaacatttt ctgcagaaac
     7741 aatcgtctca aatcgttcaa acagattgtt cttcttcaat aaaagttcaa tgactgctcg
     7801 ttggttactg gaagcgacaa ctttgggaat ctgatgttct tctaaaaaag agaggagttc
     7861 caacacaccg ggcttcattt gtaccgctcc ttgcgaaaaa cgttcaagcg tttcctggta
     7921 tgaatcatct atgaatcttt gtacacttgt tttgccaaat tccgagaaaa tcatatgata
     7981 attcgcccat acttcttcat ctgaaacacc taagaatttt aaatacaggt ctttatcata
     8041 aggaaaaccc atcttgtctg ctactacttg tgtggcttcg taatacacta actctgtgtc
     8101 gaacagcaaa ccatccatgt caaaaatcac tgcattatac ttcatgatct cctcctaatt
     8161 gtattaataa atggcgaact tctgaaatga aataaagtga accggtcaca actaatacgt
     8221 cttcatttgt catcttttcc aatatatctg ctaatccgaa ttgccacaat gaaacgattg
     8281 atactctctc acttgctaaa tctgatactt cacttaattc gatggctttt ggatgttcaa
     8341 aggtcgtcaa ataaatatgg acatttggta cttgctgcaa tcgttctagc atttctctaa
     8401 catttttagt tcgtaaggcg gaaaacaaaa tgttgatttg atatcctttg aattcttttt
     8461 tcaaattctc aacaagccgg ttcattgcat gcgtattatg ggcaccatct aaaacaacta
     8521 atggctcgtt actcaaacgc tccattcttc ctggccatcg agatttcttc aatcccttca
     8581 aaacatcttt ttctcggaaa ggcagctttt ccaattgaca gtaaacaaaa tacaattcga
     8641 tggctactcc tgcattttca gcttgatgtt gccctaaaag cggagtggtt aattgaggga
     8701 tctttcctat ttcattaaaa aattcaaata cttctcccca catctcatca ggatgcagat
     8761 agtttatttt ataattttcc ccgtatacat aaagcggtgc attttttgct ttagctgttt
     8821 gttggatgac agtaaaagct tctggggcaa tatttcctgt tactactgga acgccttgtt
     8881 tgatgattcc agctttttgt gcagcgattt cttcaattgt atctccaagt atttcggtat
     8941 gatcaagtcc aatcgttgtt attcccgtca gcattggtac agctacattg gtagaatcca
     9001 ataagccgcc taagccaact tcgataatcg ctacgtccac tttcttcatc aaaaaataat
     9061 caaatgccat tgctgttaat gtctcgaatt cagtaatacc agctactgct tcaaattgat
     9121 caagttgttt gatcagtggc tgatattttt ttacaagctg gatcaaatca ttgtctggaa
     9181 tgcttttgcc attgattgcg atccgttcat tgaacgtttc gatataaggt gaagtaaatg
     9241 tacctactgt cagcccagcc tcttctaata ggcttctcaa ataagctaca gtagaacctt
     9301 ttccgtttgt tccagcgata tggatcgttt ttacttttct ctctggatgc cctaccactt
     9361 ctaataaagc ttcgactcgg tcaaggccag gacgtgaacc aaatggtaat cgactatgga
     9421 tccattctat tgcttcttca atcgtcatca acaattcccc catttctctt ttattataac
     9481 aaatagaaca cataagaaaa ataaaagtat gacaaagaga aaagaaacag agagaggaac
     9541 gattttatca actactttat tgactcttga tacatgatcc acctccctcc ttctcctaca
     9601 taataagagt agactaaaaa agagatgcga caaaatttat gtcacatctc cttatgaatc
     9661 gaagctaaga gtgaggctca aactctttcc tgtaacgatg ttcaatcagc tagcttttag
     9721 taatagctag ctgatttcac actctctttt tctattctta ttgaatagta cgcaaacttt
     9781 cgattcgttc tttgacagcc gtttgcttct ctaaataatc tttttctttt gcacgctctg
     9841 cctctactac ttcttccggc gcgttagaaa caaaacgttc attagaaagt tttccttgga
     9901 cacgttttac ttcgcttgtc cacttttcca gttctttttc taatcgtttg atttcttctt
     9961 caatattgat caatcctgct aacggcaaga agatttctgc acctgtcaga acagctgaca
    10021 tcgctagatc tggcgcagtg atctcacttg atatcgtcaa ctcttcggga ttacagaagc
    10081 gttcgatata gcttgtattt tcaactaaaa attgatcgat tttagcatcg tttgttttaa
    10141 ttagcaacgt aattggttta gacaatggtg tattcacttc tgaacgaata tttcgaacgg
    10201 ctcgaatcaa ttctttcaat acttccatcc ctttagaagc tgtttcatca tcaaactctg
    10261 gacgtacaac aggatattct gccactacta gagaatttcc ctgatgagga atatgttccc
    10321 atatttcttc tgtaacgaat ggcatgattg gatgcaataa acgtaggatc tgatcaagtg
    10381 tatggactaa gatgctacgg gtggtttgtt ttgaaacagc atcatctcca taaagtactt
    10441 ctttactcat ttcgatgtac cagtcacaaa aatcatccca gataaagtta tacagttgtc
    10501 gacctgcttc accaaattca aaacgatcaa atagctcagt tactcgttcg atcgtttcat
    10561 tcaaacgagt aaggatccac cggtcagcca ctgatttttc tccagataaa tcgatctctt
    10621 ctacggtcat tccttcgata ttcatgataa cgaaacgtga agcattccag attttgttga
    10681 taaagttcca agaagcatcc attttttcat agctgaagcg gacatcttgt cctggtgcag
    10741 aaccattcga taagaaccag cggagagcat ctgctccata cttttcgatt acttccatcg
    10801 gatcgattcc attacctaat gatttactca tcttccgccc ttgttcgtca cgaatcaatc
    10861 catgaatcaa gacattctca aatggacgtt cgccagtaaa ttccaagctt tggaaaatca
    10921 ttctgcttac ccagaagaaa atgatgtcat aaccggttac taaagtgcta gtagggaagt
    10981 atcgcttata atcttcgctt tccgtatctg gccagcccat tgttgagaaa ggccacaaag
    11041 ctgaactaaa ccaagtgtct aaaacatcag gatcttgtac ccagttttca ctatccgctg
    11101 gtgcttccat ccctacatac atttcacctg tttctttgtg ataccatgca ggaatttgat
    11161 gtccccacca taattgtcgt gagattaccc aatcatggac attttccatc caacgtaaaa
    11221 acgtttgatt gaatcttgga gggaagaatt ccactgcttg atctgtttct tggttatcaa
    11281 tggctttttt cgctaacggc gccattttta caaaccattg agtagacagc cgaggttcaa
    11341 caacgacacc tgtccgctcg gaatgaccca cactgtggat catcgtatcg attttaatca
    11401 atcgaccgat ttctttcaga tcttgcacga ttgctttacg agcagcaaaa cgttccattc
    11461 cagcatattt tcctgctagt tcattcatcg taccatcatc atccataaca tttacgcgtg
    11521 gaagatcatg acgattacct acctcaaagt cgtttggatc atgtgctgga gtgattttta
    11581 ctacacctgt cccgaattcc atatctacat attcatctgc aatgattggg atttgtttat
    11641 tgactaaagg tagaatcact tttttgccga tgagcgcttg ataacgctcg tcttctggat
    11701 gaacagcaat cgccgtatct cccaacatcg tttctggacg ggttgtcgca atttctacta
    11761 cgcctgatcc atctgctagt tcatagctca tatgataaaa ggcgccttcg atatctttat
    11821 gaataacttc gatatcagat agagctgttc gtgcttgagg atcccagttg atgatatatt
    11881 caccacgata aatcaaacct ttttcgtata aggtaacaaa aactttacgt actgcttcag
    11941 ataatccatc atctaatgta aaacgttccc tactgtaatc taaagataag cccattttag
    12001 cccactgttc gcggatgtgg ctcgcatact cttctttcca ttcccacact tgatcgatga
    12061 acttttcacg acctagatca taacgagaaa tcccttgctc tctaagcttc gcttctactt
    12121 ttgcttgtgt cgcgattcct gcatggtcca taccaggcag ccataaagta tcatatcctt
    12181 gcattctctt ttgacgaatc agcatatctt gcaaggtcgt atcccaagca tgccctaaat
    12241 gaagttttcc agtaacattt gggggcggga ttacgattga ataaggtttt gcttttttat
    12301 ctccgctcgg tttaaacaaa tcttgttcta accaatgctg ataacgtcca gcttcaactt
    12361 cttgcggatt atattttgtt gataggttat tttcttccgt catgctgttt tcctccttta
    12421 aactaaaaaa cgtcctaaaa tactttcgta ttctaggacg tatgatttac gcggtaccac
    12481 ctaaattgca ataatcaatc attattgcct ctcaagtgag ttaacgatca cgactcgtct
    12541 atctctactc cattcaagac agaaactccc aagctacctt cactggttgt cattgagaac
    12601 ctttcagcag atagttctct ctctaagaat gaatgtgcca gttactcctc ttgttcagcg
    12661 ttatgcttca ttctacaatg gttttttttt t
//
LOCUS       DARBDN010000306         8383 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.105, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000306 DARBDN010000000
VERSION     DARBDN010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.105"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            34..150
                     /locus_tag="SCH06_003048"
     CDS             34..150
                     /locus_tag="SCH06_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEG1079525.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            166..969
                     /locus_tag="SCH06_003049"
     CDS             166..969
                     /locus_tag="SCH06_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEG1079526.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAY"
     gene            1204..1440
                     /locus_tag="SCH06_003050"
     CDS             1204..1440
                     /locus_tag="SCH06_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079527.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1447..3399
                     /locus_tag="SCH06_003051"
     CDS             1447..3399
                     /locus_tag="SCH06_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HEG1079528.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3471..3968)
                     /gene="dfrG"
                     /locus_tag="SCH06_003052"
     CDS             complement(3471..3968)
                     /gene="dfrG"
                     /locus_tag="SCH06_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HEG1079529.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            4330..5370
                     /locus_tag="SCH06_003053"
     CDS             4330..5370
                     /locus_tag="SCH06_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEG1079530.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            5468..5656
                     /locus_tag="SCH06_003054"
     CDS             5468..5656
                     /locus_tag="SCH06_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEG1079531.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(5714..6067)
                     /locus_tag="SCH06_003055"
     CDS             complement(5714..6067)
                     /locus_tag="SCH06_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079532.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            6598..7020
                     /locus_tag="SCH06_003056"
     CDS             6598..7020
                     /locus_tag="SCH06_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEG1079533.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            7017..7247
                     /locus_tag="SCH06_003057"
     CDS             7017..7247
                     /locus_tag="SCH06_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEG1079534.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            7745..7945
                     /locus_tag="SCH06_003058"
     CDS             7745..7945
                     /locus_tag="SCH06_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEG1079535.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7972..>8383
                     /locus_tag="SCH06_003059"
     CDS             7972..>8383
                     /locus_tag="SCH06_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HEG1079536.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLF"
BASE COUNT         2902 a         1345 c         1527 g         2609 t
ORIGIN      
        1 tttttgtacc cagtttaaga atacctttat catgtgattc taaagtatcc agagaatatc
       61 tgtatgcttt gtatacctat ggttatgcat aaaaatccca gtgataaaag tatttatcac
      121 tgggattttt atgccctttt gggtttttga atggaggaaa atcacatgaa aattattaat
      181 attggagttt tagctcatgt tgatgcagga aaaactacct taacagaaag cttattatat
      241 aacagtggag cgattacaga attaggaagc gtggacaaag gtacaacgag gacggataat
      301 acgcttttag aacgtcagag aggaattaca attcagacag gaataacctc ttttcagtgg
      361 gaaaatacga aggtgaacat catagacacg ccaggacata tggatttctt agcagaagta
      421 tatcgttcat tatcagtttt agatggggca attctactga tttctgcaaa agatggcgta
      481 caagcacaaa ctcgtatatt atttcatgca cttaggaaaa tggggattcc cacaatcttt
      541 tttatcaata agattgacca aaatggaatt gatttatcaa cggtttatca ggatattaaa
      601 gagaaacttt ctgccgaaat tgtaatcaaa cagaaggtag aactgtatcc taatatgtgt
      661 gtgacgaact ttaccgaatc tgaacaatgg gatacggtaa tagagggaaa cgatgacctt
      721 ttagagaaat atatgtccgg taaatcatta gaagcattgg aactcgaaca agaggaaagc
      781 ataagatttc agaattgttc tctgttccct ctttatcatg gaagtgcaaa aagtaatata
      841 gggattgata accttataga agttattact aataaatttt attcatcaac acatcgaggt
      901 ccgtctgaac tttgcggaaa tgttttcaaa attgaatata caaaaaaaag acaacgtctt
      961 gcatattaag tagttcagtt ttggagtaca aaaagtgaaa atgtaaacct aaatgagtat
     1021 caaattgcaa ctgaatttga tactcgtttt ttattgttaa atcaacgttt gttgttaatt
     1081 tacaccacaa aatgtaagtt aaaatgtata taaaaatgcg aacgtgaaat aattattgta
     1141 ggaatgcaaa ttggtgtgtt aaaatggtta caatttacta agcaaaaagg ggtgcatttt
     1201 cctatgcaat ttcttgagcc aaaaaataag aacgctaagt ctgtggattg ggaaatatca
     1261 gagcaagtaa gggtgatagt taagcaatac gctgaatatg cagagcgtac tgaaagcgaa
     1321 gcagtggatg aattcttatt gaacatttta gacgataaga agtttattga atggattgcc
     1381 aacaagcgaa gtaataagcg gattgttgaa aaaatgggta tcaaagatag agtgggttga
     1441 tagacaatga ccaagcttaa aagattagcc acgaaggaag atgaaattgt agatgttaaa
     1501 attccgattt caaacgaaga attaaaagat agggctaaac aatatgattt attaactcca
     1561 aaacgatttg caacaaggta taacaaaatg ttgttcttgc caacgtcttt taaatggaac
     1621 ggttctgaat atcccattca atataattac tgcatcaatc cgttttgttg taattttggg
     1681 aaagaacagc acaaattcaa agatgtaaaa gggaaaccaa gtcgatataa aatgactggt
     1741 agttccaaag ataaaggtca taaaggtatg tactgcaatg acaatcctat tggcagaggt
     1801 gtatcgcaaa actgtacagt aaccccttta tctaattggt ctgttgttga agaaattaaa
     1861 cgccttatag aaatcaatag catccaagat gttgagccag attatcaatt tcataaagaa
     1921 ggctgctcgg aagaagaatc aaccccattc aatgagccga agcaatttta caaaaggggg
     1981 aaaagtaggg gcaaatctca acgctatcaa tgtaaggcgt gtaagaagtt cactaatgtt
     2041 ctaccaaaaa gagaagaaac cactacttat caccaacaaa agaacaccat tcttccaatg
     2101 ttcgctaaga tggttgttgg aagggtttca gtcagtcgta cttgtgatat tttaggaatt
     2161 ggagttggaa cctactatca taagctggag tggctgtata ggcgttgttt ggagttttta
     2221 gaacgatatg agacacaacc ccttcaaaca aagaaattta acgagatgtg gcttaatacg
     2281 gacaagatgc actactacct aaataacgtc cgtaagaaag gacaaggttc aaagaaatat
     2341 acggggtttg aagaccttaa tatgcaaacg tatatagttg tatctgctga ggtcttatca
     2401 agatatgtgt tccgttctga tgttgcctat gattggaata tttcaatgga tgaattaaat
     2461 gaagatacaa gaaaattcaa agaagaccat ctcaatactt ttagtcgtaa aaatgatagg
     2521 ttagattggt cttattatcc acaagaacca tccgctaacg atagcgaaaa taggaatgct
     2581 tatcttcacg aattagggaa aattactaat aggagtagat ttgtcgatgg tttaaatgtt
     2641 gatgctcctt atactacaac tgctcactat tggttaatta aacaaatggt taatgccgac
     2701 gaatggcgaa tgattagtga tgatgacttc tctattagaa acgcctttta tagagtattc
     2761 acgaaagaat taaggttgag cgatgcacat cattttattt gccaagttaa caagacgaaa
     2821 agcagaaaac aatgcttaaa agaattcgga caagcaaaag cagaactgct cgattgggga
     2881 gatatcagag gattcaaaac aaagtttcta cggactttgg catctcatta tctaactgaa
     2941 ttactaacaa gtcatcaatt ccacgaagag gctattagta aagatggaga aagatatcgc
     3001 aaatatgccg ataaccctat caaacatcca ttagccacta aggataaagg attttattca
     3061 gttgattgta gaacggattt atctgctctg gaaccaaacg aaatcgcaaa gatgctatta
     3121 aatgttaatg accattcgac caatagcttt attcaacaga taagacgtta tatatcatct
     3181 cttgaaagac cattaacaac agctcgtggt gataagaaga gctatattta cgctaacttc
     3241 aatccgaagt atgctcaatt tgcgattaca attctaagaa cttactacaa cttttgtcgc
     3301 ccttttaaat cagcggataa aaaggttttg acacctgctc aaagattagg gattacagat
     3361 aaacaatttg attggaaaga tataatttat ttcaaatgac aaaaagagct tggagtaatc
     3421 ccaagctctt gtgctttatc tttactgttc ttcttcaatt aacgcacccg ttaactcaat
     3481 aagttttttc tttcatatac atgaaaatag tagttatacg gatttttatc attctttatc
     3541 cctttttggg caaatacctc attccattcc tcataattca cttctggaaa aaaagtatct
     3601 ccttcgaatt catgatgtat ttttgtgatg tacattttct caacataagg gaaaaacaaa
     3661 ttataaatct gttctcctcc gaaaataaaa atttcttctt cgtttttaca taactcaaaa
     3721 acatcttcta ttgaatgaac aatttcacaa ccattaaagg taaacccctt atctctcgtc
     3781 agaataatat ttcttctgtc aggtaaggct cttccgattg attcaaggtt cttcctacct
     3841 aatattatcg gatgtccctt tgtagtattt ttaacatatt cccagtcctt gggaatcctc
     3901 caaggaatgt cattctcttt gccaatcact ctattcttat ccatcgcagc aatcaaagaa
     3961 actttcattt ataacacagc ctttttaact aatttaccat ctaatttctt atttctatca
     4021 aaaaaccttt tctcattatc ctgcccgtta gttgaataag caattttttc tataagttat
     4081 attatcataa taccacaaaa tcacaaattt tcattcaatt atcattttca attgcatttt
     4141 ataaatcatt ttgtatgtaa tttggtatgt aagttaaaat gaaaaaagta gtccattttg
     4201 aagtacattt tgtcattttg tactccaaaa ctgaactact tacttgcata tatacgcctt
     4261 tatagtggag tactacattt acgagattcg gttagagtat cagaaaaaga aaaaataaaa
     4321 gttacagaaa tgtatacttc aataaatggt gaattatgta agattgatag agcttattct
     4381 ggagaaattg ttattttgca aaatgagttt ttgaagttaa atagtgttct tggagataca
     4441 aaactattgc cacagagaaa aaagattgaa aatccgcacc ctctactaca aacaactgtt
     4501 gaaccgagta aacctgaaca gagagaaatg ttgcttgatg cccttttgga aatctcagat
     4561 agtgatccgc ttctacgata ttacgtggat tctacgacac atgaaattat actttctttc
     4621 ttagggaaag tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag
     4681 atagaactaa aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat
     4741 accattcaca tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca
     4801 ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat
     4861 caatcatttc aaaatgcagt tatggaaggg atacgctatg gttgcgaaca aggattatat
     4921 ggttggaatg tgacggattg taaaatctgt tttaagtacg gtttatacta tagccctgtt
     4981 agtactccag cagattttcg gatgcttact cctattgtac tggagcaagc ctttagaaaa
     5041 gctggaacag aattgttaga gccatatctt agttttaaag tttatgcacc acaggaatat
     5101 ctttcacggg catataacga tgctcccaaa tattgtgcaa atatcgtaaa tactcaactg
     5161 aaaaataatg aggtcattat tattggagaa attcctgctc gatgtattca agattatcgc
     5221 aatgatttaa ctttttttac aaatgggctt agtgtttgtt tagcagagct aaaaggatat
     5281 caggttacca ctggcgaacc tgtttgccag acccgtcgtc taaatagtcg gatagataaa
     5341 gtaagatata tgttcaataa aataacttag tgcgttttat gttgttatat aaatatggtt
     5401 tcttattaaa taagatgaaa tattctttaa tatagatttg aattaaagtg gaaaggagga
     5461 gattgttatt ataaactaca agtggatatt gtgtcctatt tgtggaaata aaacaagact
     5521 acgaatacga gtggatacta tacttaaaaa tttcccttta tactgcccca aatgtaagaa
     5581 cgaaacttta attaatgttc aaaaaatgaa tataataaca atcaaagagc cagacgccaa
     5641 gacgcagagc cgataatttg agaaatgaaa ctctcatctt atcggctctt tttgtttatc
     5701 tgaattttac tgactagcct tcaatatttc ttgcttcatt gatacctttt gctagtgctt
     5761 ccattaagga tagttctttg tctgtaaagc tatccatgta tttttctacc tgtaaccttc
     5821 gagtgctttt aatcaaatta tctgtaggta agaaaaattc atcaatagat acatggagta
     5881 atgatacaag atcatacagc acttgtgtac ttgggtgttg tcctttgttt tctatatttg
     5941 ttaaataacg tgggtcaatt tcaatcattg ttcccacttg ttcacgagtg agaccccgtt
     6001 tcattcgagc ctctttaatc gctaaaccaa cggctctaaa atcgtattta tcttcttttt
     6061 tacgcatact aaatcacctc tatacatttt actgttccta tataaccata aacaggtata
     6121 gaaaaacatg ttatatagtt tatgagttcc tatagaacac tgtggaattt attaatgcga
     6181 tgaatccaat ttcaaataga aaggtcgctg attttattta cctatacaac tttataaaat
     6241 ttagtcatac tcctagaaag tagataaaat tggcgactta atggagggaa aagtcgccat
     6301 gagaaagata atctgtcatc tagttctctt aattaagttc ttatcaaaaa aacttatcca
     6361 cctgtactgg atagatatga ccatcaatgt ggttttgcag attacataga tagaaaaatc
     6421 aaagcatatg aacagagaaa acaatctgtt tatgtgcttt tttggtcact taataaatat
     6481 cttttaggat ttctcttcat ttatgcaaca aatcccccgt tcgtgtcggg gtttagtatg
     6541 aagggagata aagaagcaca tgccactccc tttcacgaca gaaagggggt gaaaagcatg
     6601 aaaccatctt cttttcaaga aaccatagaa aatcagtttg actatatctg caaacaagtt
     6661 attgaagatg aacgaaaaga ttacttcaaa catctagaca gactatcagc aaaagaagtc
     6721 tcgttttctg atatagataa ctaccttgtc aactcttttt ctactgttga tacgtacgtc
     6781 actgatttcc aactatttaa attatttgga ttaagaatca atgttgaaag tgatttatta
     6841 agtgaagccc tgcgtcatct ttcagagaaa aaacggaaca ttattttact tcattacttt
     6901 atggatatga gtgatgtgga gattgcggag ttactaaatt tgaatcgttc gactgtttat
     6961 cgtcatcgaa taagtggact agccatgatt aaagaattca tgaaggagtg taaagaatga
     7021 aaacagctta tccaagggtt cccttccccc tcattgtaaa ggcgacagat ggcgacgtgg
     7081 aagcaattaa tcagattgtt aaacattatc gagggtatac ctcaaaacgt tcattacgtc
     7141 gcatgacaga cgaatatgga aattctcata tggttattga tgaaacccta cgtggcagaa
     7201 tggaaacgaa actcatctct aagattttat cgttcgaaat taaatagtcc cattttttcg
     7261 tggaagcgtg tcgaatcgta tccacgcttc ccgatttggg aggtttgtta ttccatcaaa
     7321 gcatattgtg tgttcagtag gttttgatag gctaacaagc caaacgttct ttgacaacca
     7381 aataaaggca atcgaatacg tttcggtaag aaaagagctg atgaactaac acgccatgac
     7441 ctacaaaatt agtgagcgat tcatgttagt aattcgaaag taatctttag caggattgct
     7501 gccatgactt tcttatcgtg ataatgatac tcccgtatag ccatagtccg agcgttagaa
     7561 gcgtcacagg caatgggtac ggctacatga gaaccatgca gaagtgaaat tcctgtgagc
     7621 tttgctagag ctgttcgatt gctaagatat tcttctcttg tcagtgtatt attataaaac
     7681 tatttgatat aattataggt gaatattgga gttttcctag cctataattg ggaaaggagt
     7741 aataatgata acggtcacaa aaaaggattt agttgagcta ggatatggaa cttctttttc
     7801 agcagacatc ataaaaaaag caaaagaatt gatgattaca aaagggcata tctactatca
     7861 atctcgaaag ctagatagag tccctcgtga agctgttgaa gaaattctag gaattcggtt
     7921 ttcaaatgaa aacaggtctg agtagttttt gcacagtaag gagtaaaaac tatggttaaa
     7981 gacccaataa aaaaagcaaa gaatggaacc tattattttc gtgcaaatct aggttatgat
     8041 tctaaaggga aaaaaattca aaaatatcgt agtggattca ctactaaaaa agaagcaaga
     8101 gaagaatatt cgaaactgct attgatgaaa ccagaagaat taagtgagaa taaggataaa
     8161 atgacgttta aacattatat ctttgaaatt ttccttccat ggtataagac acaggtaaag
     8221 ctcagaacat atgaaaatcg cttaccaact attaagaagc atttctctta ttttgataaa
     8281 atggctgttt ccgatattga gcctattgat gtgcaaaatt ggcaactaaa attatcaaag
     8341 aagtgtaagt cttcttatgt aagagctgtt caaggactat ttt
//
LOCUS       DARBDN010000307         8158 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.106, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000307 DARBDN010000000
VERSION     DARBDN010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.106"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(134..577)
                     /locus_tag="SCH06_003060"
     CDS             complement(134..577)
                     /locus_tag="SCH06_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEG1079537.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="SCH06_003061"
     CDS             complement(795..2135)
                     /locus_tag="SCH06_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEG1079538.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="SCH06_003062"
     CDS             2404..3300
                     /locus_tag="SCH06_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEG1079539.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="SCH06_003063"
     CDS             complement(3450..4391)
                     /locus_tag="SCH06_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEG1079540.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="SCH06_003064"
     CDS             4517..5638
                     /locus_tag="SCH06_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEG1079541.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="SCH06_003065"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="SCH06_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEG1079542.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="SCH06_003066"
     CDS             7426..7992
                     /locus_tag="SCH06_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEG1079543.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
BASE COUNT         2709 a         1513 c         1605 g         2331 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatac
//
LOCUS       DARBDN010000308         5613 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.131, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000308 DARBDN010000000
VERSION     DARBDN010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.131"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(40..1026)
                     /locus_tag="SCH06_003067"
                     /pseudo
     CDS             complement(40..1026)
                     /locus_tag="SCH06_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
     gene            1178..1873
                     /gene="vanR"
                     /locus_tag="SCH06_003068"
     CDS             1178..1873
                     /gene="vanR"
                     /locus_tag="SCH06_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEG1079544.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1851..3005
                     /locus_tag="SCH06_003069"
     CDS             1851..3005
                     /locus_tag="SCH06_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEG1079545.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            3220..4188
                     /locus_tag="SCH06_003070"
     CDS             3220..4188
                     /locus_tag="SCH06_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEG1079546.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            4181..5212
                     /gene="vanA"
                     /locus_tag="SCH06_003071"
     CDS             4181..5212
                     /gene="vanA"
                     /locus_tag="SCH06_003071"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEG1079547.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            5218..5583
                     /locus_tag="SCH06_003072"
                     /pseudo
     CDS             5218..5583
                     /locus_tag="SCH06_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX"
BASE COUNT         1697 a         1091 c         1262 g         1563 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaacccta tttccgataa ccgtgtattg
       61 aaaggcatct tcgaagccat tatccaatat ttcgcaggct tttgtatatt taggctggtc
      121 gatatattca ccgactaagg cattcttagc tgttcgagcg agttcaatat ccgtaaactt
      181 aaagatcgct tttactgctt ctctaaacgg ttttgaattc ttttttggaa tggaactgaa
      241 gatgtttctt aaaaaatgga cctggcatct ctgccaactt gcgttggtaa atgacttacg
      301 aatcgcagac actaggcctt tatgggcatc agaaatgatg agttctgtcc cctttaggcc
      361 gcgttctttt aagtattcaa agaagatgga ccatgtgtca tcactttctt cattttgaat
      421 catgaagcca atgatttcac ggtcgccacc ttctgttatc ccgatcgcaa tatggcagct
      481 tttagaaagc actcgatggt cctcacggac ttttatgtag agaacatcag tcatcagata
      541 aggataattc gtacctgaga gtgaacggtt ctgccattcg ttgaccatcg ggtctaactg
      601 ctcagtcagg ctagaaacaa aagatttcga tacagatttt ccacatagct cttcaacaat
      661 ctttgaaact ttacgtgtcg aaacgcccga aacatacatc tcaagcattg aagcgagcag
      721 tgccttttca tttcgctgat aacgctcaaa caccgtcggt gaaaattcac catcacgtgt
      781 tctaggcact tttaattcga gtgtacccac acgagtcgta aagtctcgct cataatagcc
      841 atttctttga ctctgacgac tttctgaacg ttcatagtca tcggcttgaa tatattctgt
      901 tcgttgattt tccatcaatt ggttgaaaac agtggttaaa atatttttag aaacatcatc
      961 ttttaccgaa tgttcaataa tactttgaac ctcttcgttg ttcagtgtaa aatgtacttg
     1021 ggtcatgtaa cgtcctcctg ggtatgtttt tgtggttaaa aacattgtac cgtaaaaggg
     1081 ctgttacatg gccttttatc ttttacacaa ttatatggac tttatcctat aatctgataa
     1141 attattaagg gcaaacttat gtgaaagggt gataactatg agcgataaaa tacttattgt
     1201 ggatgatgaa catgaaattg ccgatttggt tgaattatac ttaaaaaacg agaattatac
     1261 ggttttcaaa tactataccg ccaaagaagc attggaatgt atagacaagt ctgagattga
     1321 ccttgccata ttggacatca tgcttcccgg cacaagcggc cttactatct gtcaaaaaat
     1381 aagggacaag cacacctatc cgattatcat gctgaccggg aaagatacag aggtagataa
     1441 aattacaggg ttaacaatcg gcgcggatga ttatataacg aagccctttc gcccactgga
     1501 gttaattgct cgggtaaagg cccagttgcg ccgatacaaa aaattcagtg gagtaaagga
     1561 gcagaacgaa aatgttatcg tccactccgg ccttgtcatt aatgttaaca cccatgagtg
     1621 ttatctgaac gagaagcagt tatcccttac tcccaccgag ttttcaatac tgcgaatcct
     1681 ctgtgaaaac aaggggaatg tggttagctc cgagctgcta tttcatgaga tatggggcga
     1741 cgaatatttc agcaagagca acaacaccat caccgtgcat atccggcatt tgcgcgaaaa
     1801 aatgaacgac accattgata atccgaaata tataaaaacg gtatgggggg ttggttataa
     1861 aattgaaaaa taaaaaaaac gactattcca aactagaacg aaaactttac atgtatatcg
     1921 ttgcaattgt tgtggtagca attgtattcg tgttgtatat tcgttcaatg atccgaggga
     1981 aacttgggga ttggatctta agtattttgg aaaacaaata tgacttaaat cacctggacg
     2041 cgatgaaatt atatcaatat tccatacgga acaatataga tatctttatt tatgtggcga
     2101 ttgtcattag tattcttatt ctatgtcgcg tcatgctttc aaaattcgca aaatactttg
     2161 acgagataaa taccggcatt gatgtactta ttcagaacga agataaacaa attgagcttt
     2221 ctgcggaaat ggatgttatg gaacaaaagc tcaacacatt aaaacggact ctggaaaagc
     2281 gagagcagga tgcaaagctg gccgaacaaa gaaaaaatga cgttgttatg tacttggcgc
     2341 acgatattaa aacgcccctt acatccatta tcggttattt gagcctgctt gacgaggctc
     2401 cagacatgcc ggtagatcaa aaggcaaagt atgtgcatat cacgttggac aaagcgtatc
     2461 gactcgaaca gctaatcgac gagttttttg agattacacg gtataaccta caaacgataa
     2521 cgctaacaaa aacgcacata gacctatact atatgctggt gcagatgacc gatgaatttt
     2581 atcctcagct ttccgcacat ggaaaacagg cggttattca cgcccccgag gatctgaccg
     2641 tgtccggcga ccctgataaa ctcgcgagag tctttaacaa cattttgaaa aacgccgctg
     2701 catacagtga ggataacagc atcattgaca ttaccgcggg cctctccggg gatgtggtgt
     2761 caatcgaatt caagaacact ggaagcatcc caaaagataa gctagctgcc atatttgaaa
     2821 agttctatag gctggacaat gctcgttctt ccgatacggg tggcgcggga cttggattgg
     2881 cgattgcaaa agaaattatt gttcagcatg gagggcagat ttacgcggaa agcaatgata
     2941 actatacgac gtttagggta gagcttccag cgatgccaga cttggttgat aaaaggaggt
     3001 cctaagagat gtatataatt ttttaggaaa atctcaaggt tatctttact ttttcttagg
     3061 aaattaacaa tttaatatta agaaacggct cgttcttaca cggtagactt aataccgtaa
     3121 gaacgagccg ttttcgttct tcagagaaag atttgacaag attaccattg gcatccccgt
     3181 tttatttggt gcctttcaca gaaagggttg gtcttaatta tgaataacat cggcattact
     3241 gtttatggat gtgagcagga tgaggcagat gcattccatg ctctttcgcc tcgctttggc
     3301 gttatggcaa cgataattaa cgccaacgtg tcggaatcca acgccaaatc cgcgcctttc
     3361 aatcaatgta tcagtgtggg acataaatca gagatttccg cctctattct tcttgcgctg
     3421 aagagagccg gtgtgaaata tatttctacc cgaagcatcg gctgcaatca tatagataca
     3481 actgctgcta agagaatggg catcactgtc gacaatgtgg cgtactcgcc ggatagcgtt
     3541 gccgattata ctatgatgct aattcttatg gcagtacgca acgtaaaatc gattgtgcgc
     3601 tctgtggaaa aacatgattt caggttggac agcgaccgtg gcaaggtact cagcgacatg
     3661 acagttggtg tggtgggaac gggccagata ggcaaagcgg ttattgagcg gctgcgagga
     3721 tttggatgta aagtgttggc ttatagtcgc agccgaagta tagaggtaaa ctatgtaccg
     3781 tttgatgagt tgctgcaaaa tagcgatatc gttacgcttc atgtgccgct caatacggat
     3841 acgcactata ttatcagcca cgaacaaata cagagaatga agcaaggagc atttcttatc
     3901 aatactgggc gcggtccact tgtagatacc tatgagttgg ttaaagcatt agaaaacggg
     3961 aaactgggcg gtgccgcatt ggatgtattg gaaggagagg aagagttttt ctactctgat
     4021 tgcacccaaa aaccaattga taatcaattt ttacttaaac ttcaaagaat gcctaacgtg
     4081 ataatcacac cgcatacggc ctattatacc gagcaagcgt tgcgtgatac cgttgaaaaa
     4141 accattaaaa actgtttgga ttttgaaagg agacaggagc atgaatagaa taaaagttgc
     4201 aatactgttt gggggttgct cagaggagca tgacgtatcg gtaaaatctg caatagagat
     4261 agccgctaac attaataaag aaaaatacga gccgttatac attggaatta cgaaatctgg
     4321 tgtatggaaa atgtgcgaaa aaccttgcgc ggaatgggaa aacgacaatt gctattcagc
     4381 tgtactctcg ccggataaaa aaatgcacgg attacttgtt aaaaagaacc atgaatatga
     4441 aatcaaccat gttgatgtag cattttcagc tttgcatggc aagtcaggtg aagatggatc
     4501 catacaaggt ctgtttgaat tgtccggtat cccttttgta ggctgcgata ttcaaagctc
     4561 agcaatttgt atggacaaat cgttgacata catcgttgcg aaaaatgctg ggatagctac
     4621 tcccgccttt tgggttatta ataaagatga taggccggtg gcagctacgt ttacctatcc
     4681 tgtttttgtt aagccggcgc gttcaggctc atccttcggt gtgaaaaaag tcaatagcgc
     4741 ggacgaattg gactacgcaa ttgaatcggc aagacaatat gacagcaaaa tcttaattga
     4801 gcaggctgtt tcgggctgtg aggtcggttg tgcggtattg ggaaacagtg ccgcgttagt
     4861 tgttggcgag gtggaccaaa tcaggctgca gtacggaatc tttcgtattc atcaggaagt
     4921 cgagccggaa aaaggctctg aaaacgcagt tataaccgtt cccgcagacc tttcagcaga
     4981 ggagcgagga cggatacagg aaacggcaaa aaaaatatat aaagcgctcg gctgtagagg
     5041 tctagcccgt gtggatatgt ttttacaaga taacggccgc attgtactga acgaagtcaa
     5101 tactctgccc ggtttcacgt catacagtcg ttatccccgt atgatggccg ctgcaggtat
     5161 tgcacttccc gaactgattg accgcttgat cgtattagcg ttaaaggggt gataagcatg
     5221 gaaataggat ttactttttt agatgaaata gtacacggtg ttcgttggga cgctaaatat
     5281 gccacttggg ataatttcac cggaaaaccg gttgacggtt atgaagtaaa tcgcattgta
     5341 gggacatacg agttggctga atcgcttttg aaggcaaaag aactggctgc tacccaaggg
     5401 tacggattgc ttctatggga cggttaccgt cctaagcgtg ctgtaaactg ttttatgcaa
     5461 tgggctgcac agccggaaaa taacctgaca aaggaaagtt attatcccaa tattgaccga
     5521 actgagatga tttcaaaagg atacgtggct tcaaaatcaa gccatagccg cggcggttct
     5581 gttgcaaagt tttaaataaa gaataaaatc cct
//
LOCUS       DARBDN010000309         4338 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.157, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000309 DARBDN010000000
VERSION     DARBDN010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.157"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            288..1766
                     /gene="msr(C)"
                     /locus_tag="SCH06_003073"
     CDS             288..1766
                     /gene="msr(C)"
                     /locus_tag="SCH06_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEG1079548.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1813..2259
                     /locus_tag="SCH06_003074"
     CDS             1813..2259
                     /locus_tag="SCH06_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEG1079549.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2458..2973)
                     /locus_tag="SCH06_003075"
     CDS             complement(2458..2973)
                     /locus_tag="SCH06_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEG1079550.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3090..4292
                     /locus_tag="SCH06_003076"
     CDS             3090..4292
                     /locus_tag="SCH06_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEG1079551.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1304 a          728 c          941 g         1365 t
ORIGIN      
        1 aggaggtcgg aaaaatgact gcatcgatga aattacgttt cgaacttttg aataacaact
       61 aaataaattc aaaagacatg tataaacaac aatttcatgg atggagtatg tccatttttt
      121 cgaacgacag tagaataggt gaaagctatg acagatttgg tgatttagtc atagttattt
      181 cgttcagagt aggaaaagat gtgatgcagt ttttttgcaa acagattttt ctgctctttt
      241 ttagtatcga taattgttgt tttacatgaa ataggagtgt aaaacatatg gaaaatttag
      301 cagtaaatat aacaaatcta caagtcagct ttggcaacca gctagaacta tctattgatt
      361 ctcttcgtgt ctatcagcaa gatcgtatag ggatcatagg agaaaatggt gtcggtaaat
      421 cgactttgct caaactaata gccggtgaac tttttcccga tcatgggaaa atccaaacag
      481 agatcacctt caactacctg cctcaattaa cctatctcgc tgaagcaaag gacctaaatt
      541 tggaattagc cagtcatttc cagttaagac tggaagaaac ttcagagcgg aaatggagcg
      601 gaggggaaga acgaaagatc gagttgatac gtcttctttc ttcttatgaa caagggatgc
      661 ttctagacga gccaacaacc catctagata gaaaaagtat tgatcgactg attgaagagc
      721 ttcgttatta ttatggtacg ctggtttttg ttagtcatga tcgctatttt ctagatgagc
      781 tagcatcgaa aatctgggaa gtaaaagacg gagaaatccg agagttttcg gggaattata
      841 gtgcctatct cactcaaaag gaattggaga aaaagactca gctacgagaa gcagagtcga
      901 tcatgaaaga gaaaaaacga ttggaaaaat cgatccaaga aaagaaaaaa caagcggaaa
      961 agttggaaaa agtgtccagt aaaaagaaaa agcaacaaat cagactggat cggttgtctt
     1021 cctctaaaca aaaagacagt gtacaaaaag ccatccaaaa gaatgcgaaa acattagaga
     1081 gaagactcca aaaaatagga gaaacaacca agccgcagca gatgaaacaa atccgttttc
     1141 cagtaccaaa atctcttgaa ctccacagcc gctatcccat catgggacaa aatgtccaat
     1201 tggaaagaag tgggagaaca ttactggtaa atggtgattt tcagttttct ttaggtaaaa
     1261 aaatcgcgat tgtcggtgaa aatggttcag gtaagacaac cttattagaa catatccgca
     1321 aacaaggaga aggaatcctt ctctctccga aagtaagctt tcaagtatat cagcaaaagg
     1381 gttatcaaat gacatctgaa gaatccatca ttcgttttgt catgagacaa acagagtttt
     1441 cagaatcgct tgtccgtagt ttgctgaatc acttagggtt tgctcaggaa actttgacga
     1501 aaccgttatg tacattaagt gggggagaag cgacccgtct gacgattgct ttgcttttta
     1561 ctaagccaag taatgtgttg ctgttagatg aaccgactaa ttttattgat atggcaacga
     1621 tcgaagcttt agagaagcta atgcaaatat atccgggaac gattttgttt acttctcatg
     1681 attcttactt tgtcgagcgt acggctgatg aagtttatga aataaaaggg cagaaaataa
     1741 aaaaagtact tacgagaaat ttttaaatgt gctacgatga ttttcgtgac aaatttaaag
     1801 gagtggtaca gattgcctac aaataaaaaa gaaggaataa tttttacaac aatgatgtgt
     1861 tttttgatgg tcttggggat gagcgcgtat aatttatggc tgcatcaaga tcttcattta
     1921 tcaagtttgt tgattggtct agtgcctgga ttcgtggtgg ctttcatttt ggatgtcttc
     1981 atcatcggtg tgctggcgaa aaaaattgcc tttaaactac cagtaaatcc agaaagcaag
     2041 gtccaaatga tcttaactat ttcatgcttg atggttttag gaatggtgac atgtatgtct
     2101 ttattcggtg tgatcatgga acaaggaata cctgatcaat tattctctgc ttatatgaat
     2161 gcttggaaaa tgaatgtgat tgccgcttta ccgttgcagt tgatcatcgt tggcccgctt
     2221 tcaagaagtg tgctaaaagc aattcaaagt aatgaatgat ggaacactgt tatttgaaaa
     2281 aaggccttgg catgcttttt gtcatagtct cttgaatgca gttctagaaa aatagtgatc
     2341 cgaacgatag gttttggcct gtcgttcgga tcgctttttc ttttccaact gtattgctct
     2401 tttattgaag ataatttgct cttcaataga tatttctaga aaggttctgt ttatccctta
     2461 ctcaaaaaac tgctgcattt gttctcttac ttgctgacac cattggagtt cctgctgaca
     2521 aagcataatt ctgcgctgga tcacaacata acgtccaaat tcttgtttct tgtctagcga
     2581 gaggtcattc aatttttttt gatttttttg catgattttg ttcagctgtt gttctctagt
     2641 gaatagcagt ccagtagctg ttgttttatc gagcgtcgaa aaagcataga tttttgctag
     2701 aaattcatct ttttgcgtag gagcgggagt ttcctctttg atccattcct ctacaagagc
     2761 acgtccttca tcagtcaagt ggtagatctt tttttgagag tgctcgtctt tgtccaaaac
     2821 ggtcacataa ccctgctggt ctaacttggc aagcgttgta tagatctgac tgtgatgggc
     2881 ttcccaaaaa attgtgatca gctgcttcaa ttcataccca gaacgtggtt tggataaaag
     2941 cacgcataat aatatatagg ctaaagtatt cataaaaatc ctacctctcg tcttattttc
     3001 tttattatat cacagtaaag tttccacgtt ttacatgtgc atattgacat gtaaaataaa
     3061 tcatgtatga tgctaataga gagaaaggga tggaaatatt ggagaatcaa atagatatac
     3121 aagaacaaac aaatgaagaa acaaagggga aaagttcagc gctagttgta gcagctacct
     3181 gtatgatcgc ttttatggga gtgggtctag tagacccaat cttaaaaacg attgctgcac
     3241 agttaaacgc tacgccagct gaaacgaccc tgttatttac tagttacatg ttagtcactg
     3301 gtgtggtgat gctatttaca ggtttcttat ctagtcggat cggtttgaaa aaaacattga
     3361 tgacaggatt gtttatcatc gttgtattcg ctggtcttgg cggattatct gggaatatcg
     3421 gaatgctgat tgggttacgt gccggctggg gtgtcgggaa tgctttattt gtctctactg
     3481 ctttagcaac gatcgtcagt attttagttg gtaacacaga aaaagcaatc atgatgtatg
     3541 aagcagcact tggctgcgga atggctgttg gccctctagt cggtggggtc ttgggcagtg
     3601 gttcatggcg ttatccattt tttggggtag catttttgat gttttgcggt tttatagccc
     3661 tagcggtact tttacctgaa actgagaaac caaagagaaa agtaggcctt tgggaaggtg
     3721 tcaaagcgtt aagcaatcat aaacttcgtt cagttggact aatcgcattg ttatataatt
     3781 tcggattctt tactttactt gcgtatgcgc catttttatt gattggctat tctgaattag
     3841 aagtcggttt tgtatttttt ggctggggtg tgcttctggc tattgcttcg attttcgttg
     3901 caccggctct tgagcggaag tttacgactt atcggacaat tttagcagca tttgtcttat
     3961 tcattatttg tttgctgtta ttaggagctg gaacttctat gccagtcctt gtaccgatca
     4021 gcattgtgtt agcaggattt ttccaaggaa ttatcaatac actgttgacg acgattgcta
     4081 tggaaatacc aggtctgcaa cgaaacgttg cttcgtccag ctatagtttt gtccgctttt
     4141 tcggtggagc tttagcacca tttattgcag gtgtgattgg tgaacatatt ggtgaaagct
     4201 atgcgtttta ttttgcaggt gccattgttc ttatcagtgt atgttgtatc atttatcacc
     4261 gtaattattt tgctacaaat gaagaagaat aagaaatcag aggttgtgaa aaagctgtcc
     4321 tgcatcaagt cataagaa
//
LOCUS       DARBDN010000310         2193 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.194, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000310 DARBDN010000000
VERSION     DARBDN010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.194"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            complement(137..1507)
                     /locus_tag="SCH06_003077"
     CDS             complement(137..1507)
                     /locus_tag="SCH06_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEG1079552.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKYVF
                     EKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEI
                     NRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELI
                     FSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLI
                     FLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLF
                     TELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLI
                     MGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFI
                     ITVINR"
BASE COUNT          794 a          386 c          303 g          710 t
ORIGIN      
        1 atcatgtaaa cagcctgagg tgagtatatg aaggtcggaa acaagctact cgtagaaact
       61 tgcaagtgtt aaaacaatta atcgaaaaac gagtaaaatc cctcacctaa tactaaagcg
      121 agggattttt tgtatattat ctgtttatca ccgttattat aaaggtacaa ataccaagca
      181 cggttaatcc aaattgcata aattcatttt tttgtacact catgcttttc attagctctt
      241 taactgccat tagtactaag atggcgataa caacataaag tatatagtac gtccgcattc
      301 cggaagccca tactgtggga gaaaatccca taattaacct tgaacaaaat cccattatca
      361 tcaaaataac taaaaaaata gaagttttct tattgtcaaa acttaaataa attccaacaa
      421 ttaaacatag taataatgcc aagactacta aagtagctat ccaagtacct ggataaaaaa
      481 gtgacagttt cgttcctaac tctgtaaaga gattattcag gttactacta ctccaaatca
      541 ttgccctttt atttccattg acgtaagtaa agctttgacc cattgtatta ccaaaataaa
      601 taatcaggtt taagaaaaac ggtaatgcag tcaatatacg cacataatag ttttgacatt
      661 tcctatatgt tagaaggaaa attaagaaaa atagcaataa aaataagata ttcatgtcta
      721 aaaaaaacgg ctttccaaat gatgaaatac ctaaatctaa cttattaaga aagttgaaat
      781 ttttatattc aggaaaccat ttattaattt catgtgcagc acgtaatgca ttccctggag
      841 ttgtcaaaga gaaaattaat tctgctaagc ttattattga aaatactgat aacttataat
      901 tatatcgtcc attgacaatc aaatataaac taactatact tgttagaaca aaaaaacagg
      961 cgttgacttg ttcttgatta gttaaaaata tcaataaagg aatacttacc caatatattt
     1021 ttctatttat ttcttctcct cttaagagtt gaaaaaacgg ataaaaagtt agtaaactaa
     1081 atgctactgg ccactgatag ttcaaggtgg ttgctctcca accggtttcc cccattactg
     1141 tcaatggtat taaacagtat atagagcaaa ccaataataa atttttaaca tttattttct
     1201 caaaaacata cttgcaaagt aatactacaa ttcctaacat aatcgtagaa tttaataatt
     1261 tccatagcat aaagtgttta gaaaagaaca ttaagaatag ttctataata attcttgaac
     1321 tccatgtctt ataatgttct atcgaagcac ccaaatagcc aagttcatct aatctacttg
     1381 cataaactac gtcatccgct ctcatagtcg gcatatacat attaaagagt aaaaagatac
     1441 cccaaatccc tattagtaac aagatcagtt ctttgttatt cgttattttt ctattatgtt
     1501 tgttcatttt tatactcctt cttatatttc ctaatagagt ataacatagc tttaagcatt
     1561 acttaaagat aacttaaaag ttatctttta aatacttaat tgttaaatac cttatttgat
     1621 gcaaaagaaa tctacgatag tcaacaaaaa aattttcatt atatccagaa aaatttttct
     1681 tagttaagga cctatggatt gcagtaatgc agaattcgtc gaataaactg ccaaagacat
     1741 acaatcatat tgcttttaaa attgacgaac aagatataga ttcgtttgtc tcaaaaatcc
     1801 aaatgttagg tttaactgtc gaaccaggac gttctcgtgt gaaaggcgag gcttcttcaa
     1861 tttactttta cgactatgat aatcacctct tcgagttaca taccggtact ctccaggaac
     1921 gtttaaaatc ctacaattcc actacctgag actagtaatg actagtctct ttttatggcc
     1981 tctgatcccc ccattgagcg aatactaata gggcttcgaa ttgatctgtt caatctttaa
     2041 gcaatatccc tcaaatgagt ttggaaagtt tagtgattca tcacaaatac ttaaatacat
     2101 gtagttatat atagattgag gttcttgtga gcgtatgctc gtgtgggttc aaatcccatc
     2161 gtctgcatcc atctttccaa aacaagcggc tag
//
LOCUS       DARBDN010000311         1504 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.215, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000311 DARBDN010000000
VERSION     DARBDN010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.215"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            262..345
                     /locus_tag="SCH06_003078"
                     /pseudo
     CDS             262..345
                     /locus_tag="SCH06_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="SCH06_003079"
     CDS             394..477
                     /locus_tag="SCH06_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HEG1079553.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="SCH06_003080"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="SCH06_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEG1079554.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DARBDN010000312         1369 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.225, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000312 DARBDN010000000
VERSION     DARBDN010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.225"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            <1..152
                     /locus_tag="SCH06_003081"
     CDS             <1..152
                     /locus_tag="SCH06_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEG1079555.1"
                     /translation="YSKEIGCSEMFLITDKGNPRACHVYEKLGGKNDYKDEIVYVYDY
                     EKGDK"
     gene            153..>1369
                     /gene="aac(6')-Ie"
                     /locus_tag="SCH06_003082"
     CDS             153..>1369
                     /gene="aac(6')-Ie"
                     /locus_tag="SCH06_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HEG1079556.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCD"
BASE COUNT          567 a          103 c          237 g          462 t
ORIGIN      
        1 aatattctaa agagattggt tgttctgaaa tgtttttaat aactgataaa ggtaatccta
       61 gagcttgcca tgtatatgaa aaattaggtg gtaaaaatga ttataaagat gaaatagtat
      121 atgtatatga ttatgaaaaa ggtgataaat aaatgaatat agttgaaaat gaaatatgta
      181 taagaacttt aatagatgat gattttcctt tgatgttaaa atggttaact gatgaaagag
      241 tattagaatt ttatgatggt agagataaaa aatatacatt agaatcatta aaaaaacatt
      301 atacagagcc ttgggaagat gaagttttta gagtaattat tgaatataac aatgttccta
      361 ttggatatgg acaaatatat aaaatgtatg atgagttata tactgattat cattatccaa
      421 aaactgatga gatagtctat ggtatggatc aatttatagg agagccaaat tattggagta
      481 aaggaattgg tacaagatat attaaattga tttttgaatt tttgaaaaaa gaaagaaatg
      541 ctaatgcagt tattttagac cctcataaaa ataatccaag agcaataagg gcataccaaa
      601 aatctggttt tagaattatt gaagatttgc cagaacatga attacacgag ggcaaaaaag
      661 aagattgtta tttaatggaa tatagatatg atgataatgc cacaaatgtt aaggcaatga
      721 aatatttaat tgagcattac tttgataatt tcaaagtaga tagtattgaa ataatcggta
      781 gtggttatga tagtgtggca tatttagtta ataatgaata catttttaaa acaaaattta
      841 gtactaataa gaaaaaaggt tatgcaaaag aaaaagcaat atataatttt ttaaatacaa
      901 atttagaaac taatgtaaaa attcctaata ttgaatattc gtatattagt gatgaattat
      961 ctatactagg ttataaagaa attaaaggaa cttttttaac accagaaatt tattctacta
     1021 tgtcagaaga agaacaaaat ttgttaaaac gagatattgc cagtttttta agacaaatgc
     1081 acggtttaga ttatacagat attagtgaat gtactattga taataaacaa aatgtattag
     1141 aagagtatat attgttgcgt gaaactattt ataatgattt aactgatata gaaaaagatt
     1201 atatagaaag ttttatggaa agactaaatg caacaacagt ttttgagggt aaaaagtgtt
     1261 tatgccataa tgattttagt tgtaatcatc tattgttaga tggcaataat agattaactg
     1321 gaataattga ttttggagat tctggaatta tagatgaata ttgtgattt
//
LOCUS       DARBDN010000313         1350 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.229, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000313 DARBDN010000000
VERSION     DARBDN010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.229"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            47..298
                     /locus_tag="SCH06_003083"
                     /pseudo
     CDS             47..298
                     /locus_tag="SCH06_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            391..1185
                     /locus_tag="SCH06_003084"
                     /note="aph(3')-IIIa"
     CDS             391..1185
                     /locus_tag="SCH06_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEG1079557.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          425 a          234 c          322 g          369 t
ORIGIN      
        1 acattttcct ctaggaaaaa attaactagc accacgggtt atcttttata tagaagatat
       61 cgccgtatgt aaggatttca gggggcaagg cataggcagc gcgcttatca atatatctat
      121 agaatgggca aagcataaaa acttgcatgg actaatgctt gaaacccagg acaataacct
      181 tatagcttgt aaattctatc ataattgtgg tttcaaaatc ggctccgtcg atactatgtt
      241 atacgccaac tttgaaaaca actttgaaaa agctgttttc tggtatttaa ggttttagaa
      301 tgcaaggaac agtgaattgg agttcgtctt gttataatta gcttcttggg gtatctttaa
      361 atactgtaga aaagaggaag gaaataataa atggctaaaa tgagaatatc accggaattg
      421 aaaaaactga tcgaaaaata ccgctgcgta aaagatacgg aaggaatgtc tcctgctaag
      481 gtatataagc tggtgggaga aaatgaaaac ctatatttaa aaatgacgga cagccggtat
      541 aaagggacca cctatgatgt ggaacgggaa aaggacatga tgctatggct ggaaggaaag
      601 ctgcctgttc caaaggtcct gcactttgaa cggcatgatg gctggagcaa tctgctcatg
      661 agtgaggccg atggcgtcct ttgctcggaa gagtatgaag atgaacaaag ccctgaaaag
      721 attatcgagc tgtatgcgga gtgcatcagg ctctttcact ccatcgacat atcggattgt
      781 ccctatacga atagcttaga cagccgctta gccgaattgg attacttact gaataacgat
      841 ctggccgatg tggattgcga aaactgggaa gaagacactc catttaaaga tccgcgcgag
      901 ctgtatgatt ttttaaagac ggaaaagccc gaagaggaac ttgtcttttc ccacggcgac
      961 ctgggagaca gcaacatctt tgtgaaagat ggcaaagtaa gtggctttat tgatcttggg
     1021 agaagcggca gggcggacaa gtggtatgac attgccttct gcgtccggtc gatcagggag
     1081 gatatcgggg aagaacagta tgtcgagcta ttttttgact tactggggat caagcctgat
     1141 tgggagaaaa taaaatatta tattttactg gatgaattgt tttagtacct agatttagat
     1201 gtctaaaaag ctttaactac aagcttttta gacatctaat cttttctgaa gtacatccgc
     1261 aactgtccat actctgatgt tttatatctt ttctaaaagt tcgctagata ggggtcccga
     1321 gcgcctacga ggaatttgta tcgataagaa
//
LOCUS       DARBDN010000314         1153 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.243, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000314 DARBDN010000000
VERSION     DARBDN010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.243"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            1..176
                     /locus_tag="SCH06_003085"
                     /pseudo
     CDS             1..176
                     /locus_tag="SCH06_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            207..1082
                     /locus_tag="SCH06_003086"
                     /note="aph(2'')-Ia"
     CDS             207..1082
                     /locus_tag="SCH06_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HEG1079558.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          491 a           89 c          191 g          382 t
ORIGIN      
        1 tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt tattttagac cctcataaaa
       61 ataatccaag agcaataagg gcataccaaa aatctggttt tagaattatt gaagatttgc
      121 cagaacatga attacacgag ggcaaaaaag aagattgtta tttaatggaa tatagatatg
      181 atgataatgc cacaaatgtt aaggcaatga aatatttaat tgagcattac tttgataatt
      241 tcaaagtaga tagtattgaa ataatcggta gtggttatga tagtgtggca tatttagtta
      301 ataatgaata catttttaaa acaaaattta gtactaataa gaaaaaaggt tatgcaaaag
      361 aaaaagcaat atataatttt ttaaatacaa atttagaaac taatgtaaaa attcctaata
      421 ttgaatattc gtatattagt gatgaattat ctatactagg ttataaagaa attaaaggaa
      481 cttttttaac accagaaatt tattctacta tgtcagaaga agaacaaaat ttgttaaaac
      541 gagatattgc cagtttttta agacaaatgc acggtttaga ttatacagat attagtgaat
      601 gtactattga taataaacaa aatgtattag aagagtatat attgttgcgt gaaactattt
      661 ataatgattt aactgatata gaaaaagatt atatagaaag ttttatggaa agactaaatg
      721 caacaacagt ttttgagggt aaaaagtgtt tatgccataa tgattttagt tgtaatcatc
      781 tattgttaga tggcaataat agattaactg gaataattga ttttggagat tctggaatta
      841 tagatgaata ttgtgatttt atatacttac ttgaagatag tgaagaagaa ataggaacaa
      901 attttggaga agatatatta agaatgtatg gaaatataga tattgagaaa gcaaaagaat
      961 atcaagatat agttgaagaa tattatccta ttgaaactat tgtttatgga attaaaaata
     1021 ttaaacagga atttatcgaa aatggtagaa aagaaattta taaaaggact tataaagatt
     1081 gattatataa tatatgaaaa gctattataa aagacggttc tgttgcaaag ttttaaatct
     1141 actatcaaat aag
//
LOCUS       DARBDN010000315          996 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.255, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000315 DARBDN010000000
VERSION     DARBDN010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.255"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            61..>996
                     /gene="vanY"
                     /locus_tag="SCH06_003087"
     CDS             61..>996
                     /gene="vanY"
                     /locus_tag="SCH06_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEG1079559.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNWFCCKVLNLLSN"
BASE COUNT          360 a          136 c          200 g          300 t
ORIGIN      
        1 aggggaagat tctagaaata tttcatactt ccaactatat agttaaggag gagactgaaa
       61 atgaagaagt tgtttttttt attgttattg ttattcttaa tatacttagg ttatgactac
      121 gttaatgaag cactgttttc tcaggaaaaa gtcgaatttc aaaattatga tcaaaatccc
      181 aaagaacatt tagaaaatag tgggacttct gaaaataccc aagagaaaac aattacagaa
      241 gaacaggttt atcaaggaaa tctgctatta atcaatagta aatatcctgt tcgccaagaa
      301 agtgtgaagt cagatatcgt gaatttatct aaacatgacg aattaataaa tggatacggg
      361 ttgcttgata gtaatattta tatgtcaaaa gaaatagcac aaaaattttc agagatggtc
      421 aatgatgctg taaagggtgg cgttagtcat tttattatta atagtggcta tcgagacttt
      481 gatgagcaaa gtgtgcttta ccaagaaatg ggggctgagt atgccttacc agcaggttat
      541 agtgagcata attcaggttt atcactagat gtaggatcaa gcttgacgaa aatggaacga
      601 gcccctgaag gaaagtggat agaagaaaat gcttggaaat acgggttcat tttacgttat
      661 ccagaggaca aaacagagtt aacaggaatt caatatgaac catggcatat tcgctatgtt
      721 ggtttaccac atagtgcgat tatgaaagaa aagaatttcg ttctcgagga atatatggat
      781 tacctaaaag aagaaaaaac catttctgtt agtgtaaatg gggaaaaata tgagatcttt
      841 tattatcctg ttactaaaaa taccaccatt catgtgccga ctaatcttcg ttatgagata
      901 tcaggaaaca atatagacgg tgtaattgtg acagtgtttc ccggatcaac acatactaat
      961 tggttctgtt gcaaagtttt aaatctacta tcaaat
//
LOCUS       DARBDN010000316          985 bp    DNA     linear   BCT 07-NOV-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3821
            SAMEA114569774-rid20111213.guided.260, whole genome shotgun
            sequence.
ACCESSION   DARBDN010000316 DARBDN010000000
VERSION     DARBDN010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA114569774
            Sequence Read Archive: ERR12203598
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 07-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001972528.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001972528.1
            Genome Coverage       :: 135x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2023 12:18:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,088
            CDSs (total)                      :: 3,026
            Genes (coding)                    :: 2,948
            CDSs (with protein)               :: 2,948
            Genes (RNA)                       :: 62
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 23 of 78
            Pseudo Genes (incomplete)         :: 41 of 78
            Pseudo Genes (internal stop)      :: 19 of 78
            Pseudo Genes (multiple problems)  :: 4 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA114569774-rid20111213.guided.260"
                     /isolate="VRE3821"
                     /db_xref="taxon:1352"
                     /country="Denmark"
     gene            270..818
                     /gene="aac(6')"
                     /locus_tag="SCH06_003088"
     CDS             270..818
                     /gene="aac(6')"
                     /locus_tag="SCH06_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEG1079560.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          344 a          144 c          207 g          290 t
ORIGIN      
        1 aggttttatt tgtcaattca taattggttt tttttaaagc aaaagataat ctatatcatg
       61 atgaacaaac agagtttttt cctccaattg atggctttcc tgatctttcc tattttgaat
      121 aaagtgtttc tgtataattt ttttatttta taagtaagat aaataatgaa agaatagaga
      181 tactgattgg tagctaaaga tttttgagcg agaacatttc gttttttcaa aaggactgtt
      241 agaataagca agaacaaggg ggaagacgta tgataatcag tgaatttgac cgtaataatc
      301 cagtattgaa agatcagctt tctgatttac tgagactgac ttggccggaa gaatatggag
      361 acagctcggc agaagaagta gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg
      421 tagaccaaga tgagttagta ggatttattg gtgcaatccc tcaatacggt atcacaggtt
      481 gggaattgca tccattagtt gtagaaagct cccgacgaaa gaaccaaata ggtactcgat
      541 tagtcaatta cttagaaaaa gaagtagctt ccagaggagg aatcacgatt tatttaggta
      601 cggatgattt agaccatgga acaacgttaa gtcaaacgga cctgtatgag catacatttg
      661 ataaagtggc ttccatccag aaccttcgtg aacatccgta tgaattctat gaaaaattag
      721 gttataaaat cgtaggtgtc ttaccaaatg caaatggctg ggacaaaccg gatatttgga
      781 tggcaaaaac gattattcct cgaccaaatt ctcaataata aaaagaggtt gtgacagaag
      841 taatcagctt caagaaataa gaaggaattt acgaaaatta cttcttgaat ttttgtgaaa
      901 ttccaactta tttccgaaga agctactttt ggaacaccgt gtaccagagg ttgtgaaaaa
      961 gtcgcttagt ttcgagtagt aagaa
//
